title: Brief report: a quality of life instrument for adolescents with growth disorders.
abstract: This study assessed the psychometric properties of a recently developed health-related quality of life (HRQOL) instrument (Vécu et Santé Perçue de l'Adolescent -Malade, VSP-AM) in 172 adolescents receiving growth hormone. The VSP-AM was cross-culturally adapted into English and tested for internal consistency (alpha=0.78-0.89 subscales, 0.74 Summary Score), construct and criterion validity, and responsiveness. Correlations with other scales demonstrated convergent validity. Adolescents who reported HRQOL as high or low had significantly different scores (all p<0.001). Adolescents receiving growth hormone therapy differed significantly from adolescents with medical, surgical or psychiatric disorders. The VSP-AM shows reliability and validity for HRQOL measurement in adolescents with growth disorders.
authors: Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. joyce.cramer@yale.edu
authors: Joyce A
authors: JA
authors: Cramer
authors: Marie
authors: M
authors: Claude Simeoni
authors: Pascal
authors: P
authors: Auquier
authors: Stéphane
authors: S
authors: Robitail
authors: Pascale
authors: P
authors: Brasseur
authors: Ariel
authors: A
authors: Beresniak
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D006304:Health Status; D019382:Human Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D012649:Self Concept; D013514:Surgical Procedures, Operative / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires
chemical_list: D019382:Human Growth Hormone