title: [Minimal prostatic adenocarcinomas in the biopsy treated with radical prostatectomy].
abstract: OBJECTIVE
  Valuation about clinical pathologyc facts of patients having undergone a radical prostatectomy due to a minimal prostate adenocarcinoma shown at the biopsy.
  
  
  METHODS
  Retrospective analysis of patients having undergone a radical prostatectomy due to a minimal prostate adenocarcinoma shown at the biopsy in front of the remaining radical prostatectomies.
  
  
  RESULTS
  In 20 patients (7.6%) out of the 260 having undergone a radical prostatectomy between 1992 and 2004 the biopsy was informed as "minimal adenocarcinoma". These patients ranged 58 to 73 years with PSA levels from 5.2 to 17.1 ng/ml. Everyone except one were clinically T1c. At the definitive pathological study the Gleason was 6, 4, 3 and 2 in 3, 3, 8 and 4 patients respectively, with one having a minimal adenocarcinoma not graded and another one with a PIN ?. 3 showed only 1 focus with a tumoral volume less than 5% of the tissue (84.2% with significant tumor or multifocal). The final staging was 1 pT0 (PIN ?), 7 pT2a, 11 pT2b and 1 pT3a (62.5% bilaterals). Relating to the remaining patients under prostatectomy, patients with minimal adenocarcinoma presented significative differences in Gleason sum (p < 0.029) and staging (p = 0.02); no in PSA mean (p = 0.243).
  
  
  CONCLUSIONS
  Minimal adenocarcinomas of the prostate at the biopsy are significant but do present lower staging and grading in relation with the rest of patients.
authors: Servicio de Urología, Hospital Virgen del Camino, Pamplona. mmontes@cfnavarra.es
authors: M
authors: M
authors: Montesino Semper
authors: J
authors: J
authors: Jiménez Aristu
authors: P
authors: P
authors: Fernández Seara
authors: C
authors: C
authors: Sarmiento Gómez
authors: L
authors: L
authors: Ripa Saldías
authors: A
authors: A
authors: Rivas Alonso
authors: M
authors: M
authors: Pinós Paul
authors: A
authors: A
authors: de Pablo Cárdenas
authors: I
authors: I
authors: Villanueva Pérez
authors: A
authors: A
authors: Santiago González de Garibay
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011467:Prostate / Q000473:pathology* / Q000601:surgery; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies