The effects of oxytocin on the activity of cells in the anterior hypothalamus in experimental stress.
Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin. The results showed that oxytocin evoked different types of rearrangement of neuron activity both in intact and in stressed animals. The dose-related effects of oxytocin affected the latent periods of neuron responses and the nature of rearrangements in spike activity. The greater the frequency of the baseline activity of the cells, the less marked was the response of the neurons to administration of oxytocin.
Mukhitdinova
Kh N
KhN
Department of Medical-Biological Disciplines, Lipetsk State Pedagogical University.
Stamova
L G
LG
Rasulov
M M
MM
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D007031:Hypothalamus / Q000166:cytology*; D009474:Neurons / Q000187:drug effects*; D017711:Nonlinear Dynamics; D010121:Oxytocin / Q000494:pharmacology*; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D013312:Stress, Physiological / Q000503:physiopathology*
D010121:Oxytocin