title: Fatal sepsis and necrotizing pneumonia in a child due to community-acquired methicillin-resistant Staphylococcus aureus: case report and literature review.
abstract: Pediatric deaths due to community-acquired methicillin-resistant Staphylococcus aureus are rare. We describe the case of 2-y-old boy with fever and cough followed by comatose state with deteriorated respiration; the boy died of severe sepsis and necrotizing pneumonia. The etiological agent was community-acquired methicillin-resistant Staphylococcus aureus, carrying a type IV staphylococcal mecA gene cassette and the Panton-Valentine Leukocidin gene.
authors: Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Neihu, Taipei, Taiwan.
authors: Min-Hua
authors: MH
authors: Tseng
authors: Bo-Huang
authors: BH
authors: Wei
authors: Wei-Jen
authors: WJ
authors: Lin
authors: Jang-Jih
authors: JJ
authors: Lu
authors: Shih-Yi
authors: SY
authors: Lee
authors: Sheng-Ru
authors: SR
authors: Wang
authors: Shyi-Jou
authors: SJ
authors: Chen
authors: Chih-Chien
authors: CC
authors: Wang
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D005098:Exotoxins; D017809:Fatal Outcome; D006801:Humans; D007956:Leukocidins / Q000235:genetics; D008297:Male; D016106:Methicillin Resistance; D009336:Necrosis; D046915:Penicillin-Binding Proteins; D011023:Pneumonia, Staphylococcal / Q000188:drug therapy / Q000382:microbiology*; D018805:Sepsis / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus