Blackwater fever in children, Burundi.
Blackwater fever is characterized by acute intravascular hemolysis with hemoglobinuria in patients with Plasmodium falciparum malaria. Its pathogenesis and management are still debated. Nine cases of this syndrome occurred in 2003 at Kiremba Hospital in Burundi in children receiving multiple quinine treatments.
Gobbi
Federico
F
Clinica Universitaria Malattie Infettive, Ospedale Amedeo di Savoia, Turin, Italy. fedgobbi@tin.it
Audagnotto
Sabrina
S
Trentini
Laura
L
Nkurunziza
Innocent
I
Corachan
Manuel
M
Di Perri
Giovanni
G
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000962:Antimalarials / Q000008:administration & dosage / Q000009:adverse effects*; D000077549:Artemether; D037621:Artemisinins / Q000008:administration & dosage; D001742:Blackwater Fever / Q000188:drug therapy / Q000453:epidemiology*; D002063:Burundi / Q000453:epidemiology; D002648:Child; D006801:Humans; D007223:Infant; D008297:Male; D011803:Quinine / Q000008:administration & dosage / Q000009:adverse effects*; D012717:Sesquiterpenes / Q000008:administration & dosage
D000305:Adrenal Cortex Hormones; D000962:Antimalarials; D037621:Artemisinins; D012717:Sesquiterpenes; D011803:Quinine; D000077549:Artemether