Risks and benefits of azathioprine therapy.
The risk of lymphoma may be increased by about fourfold in patients with inflammatory bowel disease treated with thiopurines. The increased risk could be a result of the medications, the severity of the underlying disease, or a combination of the two.
McGovern
D P B
DP
The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford OX3 7BN, UK. dermot@well.ox.ac.uk
Jewell
D P
DP
D000963:Antimetabolites / Q000009:adverse effects*; D001379:Azathioprine / Q000009:adverse effects*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D008223:Lymphoma / Q000139:chemically induced*; D012307:Risk Factors; D012720:Severity of Illness Index
D000963:Antimetabolites; D001379:Azathioprine