title: Interventional radiology strategies in the treatment of pseudomyxoma peritonei.
abstract: OBJECTIVE
  To describe percutaneous maneuvers to treat the unusual entity symptomatic pseudomyxoma peritonei (PMP).
  
  
  METHODS
  Four patients with PMP were treated by interventional radiology techniques that included large catheters (20-30 Fr) alone (n = 3), multiple catheters (n = 4), and dextran sulfate as a catalytic agent through smaller catheters (n = 1). The causes of the PMP were tumors in the ovary (2 patients), appendix (1 patient), and colon (1 patient). Each patient previously had undergone at least two operations to remove the PMP, and all patients had symptomatic recurrence. An in vitro analysis of catalytic agents also was performed.
  
  
  RESULTS
  All four patients improved symptomatically. Follow-up CT scans demonstrated marked reduction of PMP material in all cases. One patient underwent another interventional radiology session 5 months after the first; the other three patients had no recurrence of symptoms. One patient had reversible hypotension 2 hr after the procedure. The amount of material removed varied from 3 to 6 L.
  
  
  CONCLUSIONS
  These interventional radiology techniques were effective and safe for PMP and suggest options for this difficult medical and surgical problem.
authors: Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA. ericvansonnenberg@yahoo.com
authors: Eric
authors: E
authors: vanSonnenberg
authors: Brian W
authors: BW
authors: Goodacre
authors: Gerhard R
authors: GR
authors: Wittich
authors: Seham
authors: S
authors: Ali
authors: Stuart G
authors: SG
authors: Silverman
authors: Sridhar
authors: S
authors: Shankar
authors: Kemal
authors: K
authors: Tuncali
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D011553:Pseudomyxoma Peritonei / Q000000981:diagnostic imaging / Q000628:therapy*; D015641:Radiography, Interventional / Q000379:methods*; D016896:Treatment Outcome