Metastasized angiosarcoma of the spleen in a 2-year-old girl.
Primary angiosarcoma of the spleen is rare and the prognosis is very poor. The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma. At diagnosis there were liver metastases. After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection. She remained in complete remission over 2 years from diagnosis.
den Hoed
Irma D M
ID
Department of Paediatric Surgery, Paediatrics, and Pathology, University Hospital, Maastricht, The Netherlands.
Granzen
B
B
Granzen
B
B
Aronson
Daniel C
DC
Pauwels
Patrick
P
de Kraker
J
J
van Heurn
L W Ernest
LW
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D009362:Neoplasm Metastasis; D011379:Prognosis; D012074:Remission Induction; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy