Association study of polymorphisms within matrix metalloproteinase 9 with bronchial asthma.
Matrix metalloproteinase 9 plays an important role in the development of bronchial asthma. We were interested in whether the polymorphisms -T1702A, -C1562T, R279Q and +C6T within the matrix metalloproteinase 9 (MMP-9) gene were associated with asthma in a population of 231 asthmatic children. However, we found no association. Thus MMP-9 might not be a major gene for asthma.
Ganter
K
K
University Children's Hospital, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany.
Deichmann
K A
KA
Heinzmann
A
A
D000293:Adolescent; D001249:Asthma / Q000201:enzymology / Q000235:genetics* / Q000503:physiopathology; D016022:Case-Control Studies; D002648:Child; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D020780:Matrix Metalloproteinase 9 / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*
D020780:Matrix Metalloproteinase 9