Development and biological evaluation of acyl protein thioesterase 1 (APT1) inhibitors.
Deck
Patrick
P
Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Pendzialek
Dirk
D
Biel
Markus
M
Wagner
Melanie
M
Popkirova
Boriana
B
Ludolph
Björn
B
Kragol
Goran
G
Kuhlmann
Jürgen
J
Giannis
Athanassios
A
Waldmann
Herbert
H
D000818:Animals; D001570:Benzodiazepinones / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D002454:Cell Differentiation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D015394:Molecular Structure; D016716:PC12 Cells; D051381:Rats; D013329:Structure-Activity Relationship; D013869:Thiolester Hydrolases / Q000037:antagonists & inhibitors* / Q000737:chemistry; D013997:Time Factors; D018631:ras Proteins / Q000138:chemical synthesis / Q000737:chemistry / Q000187:drug effects
D001570:Benzodiazepinones; D004791:Enzyme Inhibitors; C402226:LYPLA1 protein, human; D013869:Thiolester Hydrolases; D018631:ras Proteins