title: Thoracoabdominal aortic aneurysm repair: interplay of spinal cord protecting modalities.
abstract: BACKGROUND
  The purpose of this study was to assess the complementary use of different methods of measuring spinal cord perfusion during thoracoabdominal aortic surgery.
  
  
  METHODS
  The spinal cords of 28 patients undergoing surgery on the thoracoabdominal aorta were monitored with transcranial electrical stimulation (tcMEP) and somatosensory-evoked potentials (SSEP). Available approaches of spinal cord-protection included: Moderate systemic hypothermia, constant cerebrospinal fluid (CSF) drainage and pressure monitoring, reimplantation of segmental arteries, cardiopulmonary bypass (CPB), and staged clamping.
  
  
  RESULTS
  Fourteen of 19 patients (75%) undergoing open surgical treatment (Group I) exhibited loss of tcMEP after proximal aortic clamping. In nine cases (47%), we observed recovery of tcMEP after intraoperative interventions, while two patients subsequently developed paraplegia and three died. Seventeen of 19 patients showed loss of SSEP, with recovery in 12 cases (63%). During stent-graft implantation (Group II), one of nine patients (11%) demonstrated tcMEP loss with intraoperative, intervention-related recovery. The SSEP-recording course remained stable.
  
  
  CONCLUSIONS
  tcMEP/SSEP monitoring has proved to be an excellent means of detecting spinal cord ischaemia during surgery on thoracoabdominal aortic aneurysms. The prognostic value of tcMEP monitoring should be considered superior to that of SSEP measurements, because of its direct and rapid response to spinal malperfusion. Through combined neurophysiological monitoring, vital parameter balancing and intraoperative interventions, spinal cord perfusion improves and recovery of tcMEP and SSEP is achievable, reducing the prevalence of postoperative paraplegia.
authors: Department of Cardiovascular Surgery, University Hospital, Freiburg, Germany. weigang@ch11.ukl.uni-freiburg.de
authors: E
authors: E
authors: Weigang
authors: M
authors: M
authors: Hartert
authors: P
authors: P
authors: von Samson
authors: R
authors: R
authors: Sircar
authors: K
authors: K
authors: Pitzer
authors: J
authors: J
authors: Genstorfer
authors: J
authors: J
authors: Zentner
authors: F
authors: F
authors: Beyersdorf
mesh_terms: D000328:Adult; D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D004558:Electric Stimulation / Q000379:methods; D004569:Electroencephalography; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D010477:Perfusion / Q000379:methods*; D013116:Spinal Cord / Q000098:blood supply / Q000503:physiopathology; D020760:Spinal Cord Ischemia / Q000503:physiopathology / Q000517:prevention & control*; D016896:Treatment Outcome