title: Neurofibromatosis type 1: spinal manifestations of a systemic disease.
abstract: Neurofibromatosis type 1 (NF1) is an autosomal dominant congenital dysplasia of the neural crest cells that affects the development of tissue and structures arising from the 3 germinal layers. Affected patients may present with spinal deformities or with bone or soft tissue abnormalities. Imaging plays an important role in the evaluation of these patients. In this article, a working diagnosis approach is proposed and the spectrum of spinal imaging findings in the NF1 patient is reviewed.
authors: Department of Radiology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
authors: Carlos S
authors: CS
authors: Restrepo
authors: Roy F
authors: RF
authors: Riascos
authors: Ami A
authors: AA
authors: Hatta
authors: Rafael
authors: R
authors: Rojas
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000000981:diagnostic imaging*; D013122:Spinal Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography