Modulatory effect of fenugreek seed mucilage and spent turmeric on intestinal and renal disaccharidases in streptozotocin induced diabetic rats.
To elucidate the effect of feeding fenugreek seed mucilage and spent turmeric (10%) on disaccharidases activities, the specific activities of intestinal and renal disaccharidases viz., sucrase, maltase and lactase were measured in streptozotocin induced diabetic rats. Specific activities of intestinal disaccharidases were increased significantly during diabetes and amelioration of these activities during diabetes was clearly visible by supplementing fenugreek seed mucilage and spent turmeric in the diet. However during diabetes renal disaccharidases activities were significantly lower than those in the control rats. Fenugreek seed mucilage and spent turmeric supplementations were beneficial in alleviating the reduction in maltase activity during diabetes, however not much change in the activities of sucrase and lactase was observed upon feeding. This positive influence of feeding fenugreek seed mucilage and spent turmeric on intestinal and renal disaccharidases clearly indicates their beneficial role in the management of diabetes.
Kumar
G Suresh
GS
Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore-570 020, India. paramahans1954@yahoo.com
Shetty
A K
AK
Salimath
P V
PV
D000818:Animals; D001786:Blood Glucose; D030024:Curcuma / Q000737:chemistry*; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D004186:Disaccharidases / Q000187:drug effects / Q000378:metabolism*; D007422:Intestines / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology*; D043322:Lactase / Q000378:metabolism; D008297:Male; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013393:Sucrase / Q000378:metabolism; D029910:Trigonella / Q000737:chemistry*
D001786:Blood Glucose; D004186:Disaccharidases; D043322:Lactase; D013393:Sucrase