Bitter and sweet/umami taste receptors with differently evolutionary pathways.
In this study,we investigated the evolutionary pathways of bitter, sweet and umami receptors using bioinformatic and phylogenetic analyses. Our results showed that the distantly evolutionary relationship between bitter and sweet/umami receptors. Our results also showed that bitter and sweet/umami receptors have differently evolutionary pathways,suggesting that the different evolutionary pathways may resulte in the differences of these three receptors in function.
Shi
Peng
P
Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Huang
Jing-Fei
JF
Zhang
Ya-Ping
YP
D000595:Amino Acid Sequence; D002630:Chemotactic Factors / Q000235:genetics*; D019143:Evolution, Molecular; D006801:Humans; D008957:Models, Genetic; D008969:Molecular Sequence Data; D010802:Phylogeny; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D013649:Taste; D000098706:Taste Receptors, Type 2
D002630:Chemotactic Factors; D043562:Receptors, G-Protein-Coupled; C414724:VN1R1 protein, human; C431926:taste receptors, type 1; D000098706:Taste Receptors, Type 2