Flat-panel volumetric computed tomography: a new method for visualizing fine bone detail in living mice.
In this report, we present a new noninvasive 3-dimensional (3D) imaging technology for in vivo monitoring of the skeletal development of mice: flat-panel volumetric Computed Tomography (fpvCT). Long-term investigations of 4 mice are presented, with up to 14 scans of each mouse from postnatal day 0 to 86. Examinations of a newborn and an adult mouse, performed with fpvCT and clinical multislice CT (MSCT), demonstrate the superior image quality of high-resolution fpvCT.
Obert
Martin
M
Universitätsklinikum Giessen, Abteilung Neuroradiologie, D-35385 Giessen, Germany. martin.obert@radiol.med.uni-giessen.de
Ahlemeyer
Barbara
B
Baumgart-Vogt
Eveline
E
Traupe
Horst
H
D000818:Animals; D001846:Bone Development; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D004867:Equipment Design; D021621:Imaging, Three-Dimensional / Q000295:instrumentation* / Q000379:methods / Q000662:veterinary; D051379:Mice; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods / Q000662:veterinary