[Study on the effects of cool and hot ethanol extracts from qinglongyi on the biochemical function of tumor membrane in H22 mice].
OBJECTIVE
To study the effects of cool and hot ethanol extracts from Qinglongyi on tumor membrane protein content, lipid fluidity, and membrane close capability in H22 mice.


METHODS
The membrane protein content, by, lipid fluidity and membrane close capability were measured by means of SDS-PAGE, skinitzky assay and Zamudio method respectively.


RESULTS
The cool and hot ethanol extracts from Qinglongyi decreased the content of tumor membrane protein, the lipid fluidity and membrane close capability.


CONCLUSIONS
The cool and hot ethanol extracts from Qinglongyi can change the biochemical substance and biochemical function to cause disaggregation and death of the tumor cell, which may be one of the mechanisms underlying the anti-tumor of Qinglongyi.
Ji
Yu-bin
YB
Postdoctal Research of the Institute of Materia Medica, Harbin University of Commerce, Harbin 150076, China. JYB@hrbcu.edu.cn
Ji
Chen-feng
CF
Ma
Hong-tu
HT
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D000431:Ethanol; D006358:Hot Temperature; D031324:Juglans / Q000737:chemistry; D008114:Liver Neoplasms, Experimental / Q000378:metabolism / Q000473:pathology; D008560:Membrane Fluidity / Q000187:drug effects; D008565:Membrane Proteins / Q000378:metabolism*; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D008565:Membrane Proteins; D000431:Ethanol