title: [Frontal seizures recorded by magnetoencephalography. Case report].
abstract: BACKGROUND
  This paper reports the usefulness of magnetoencephalography (MEG) in the anatomical localization of the onset and spread of seizures.
  
  
  METHODS
  In a 34-year-old male patient who suffered from drug-resistant complex partial seizures (sometimes generalized) with loss of awareness, magnetic resonance imaging revealed a probable left frontobasal cortical dysplasia. Ictal scalp electroencephalogram showed left frontotemporal theta waves. Electrocorticography (ECoG) registered interictal polyspike discharges and located the seizure onset in the lateral orbital side of the left frontal lobe. Three seizures were registered by MEG, clinically similar to the ones usually experienced by the patient. MEG ictal spike dipole location showed seizure onset coming from the left inferior frontal gyrus (as the ECoG), spreading on to other frontal areas, insula and temporal lobe, all in the left hemisphere.
  
  
  CONCLUSIONS
  MEG may be considered as a useful diagnosis modality in the study of partial seizure physiopathology as well as in its presurgical evaluation.
authors: Centro de Magnetoencefalografía, Universidad Complutense de Madrid, Madrid, Spain.
authors: C
authors: C
authors: Amo
authors: J
authors: J
authors: Prieto-Montalvo
authors: A
authors: A
authors: Esteban-García
authors: F
authors: F
authors: Maestú
authors: A
authors: A
authors: Fernández-Lucas
authors: M
authors: M
authors: Santiuste-Díaz
authors: J A
authors: JA
authors: Periáñez
authors: M
authors: M
authors: Galiano
authors: M
authors: M
authors: Martín-Moro
authors: T
authors: T
authors: Ortiz
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000503:physiopathology; D003131:Combined Modality Therapy; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D005625:Frontal Lobe / Q000002:abnormalities / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D012086:Reoperation; D013702:Temporal Lobe / Q000503:physiopathology; D000267:Tissue Adhesions / Q000503:physiopathology / Q000601:surgery
chemical_list: D000927:Anticonvulsants