Stress-inducing effect of hypoxia of different origin and its correction with Inula Helenium L. tincture.
In order to evaluate the severity of stress, the effects of single and repeated exposure to hypoxia of different origin (hemic, tissue, and circulatory) on the classical parameters of the Selye triad, cytological characteristics of lymphoid organs, and karyometric parameters (nucleus diameters) were studied in all adrenal zones, and analysis of correlations was carried out. The corrective effect of Inula helenium L. tincture manifested in prolongation of the life-span and normalization of somatic and morphological parameters.
Zelenskaya
K L
KL
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia. ilz@pharm.tsu.ru
Povet'eva
T N
TN
Pashinskii
V G
VG
Fomina
T N
TN
Timina
E A
EA
Perova
A V
AV
D000818:Animals; D005260:Female; D000860:Hypoxia / Q000150:complications*; D038143:Inula / Q000737:chemistry*; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use*; D013312:Stress, Physiological / Q000188:drug therapy* / Q000209:etiology
D010936:Plant Extracts