title: [Prevention of post-operative pain and haemorrhage in PPH (Procedure for Prolapse and Hemorrhoids) and STARR (Stapled Trans-Anal Rectal Resection). Preliminary results in 261 cases].
abstract: Intra- and early (first week) post-operative haemorrhages are the most common complications in stapled hemorrhoidectomy PPH (Procedure for Prolapse and Hemorrhoids) and in circumferential resection of the rectal prolapse STARR (Stapled Trans Anal Rectal Resection). Performing PPH and STARR we employed a gelatin based haemostatic sealant with thrombin component (FloSeal) to control intra-operative bleeding and to reduce post-operative bleeding avoiding haemostatic stitches on suture line. We report the preliminary results on 197 PPH and 64 STARR; 44 PPH (22.4%) and 27 STARR (42.2%) were treated by FloSeal. No major post-operative bleeding was observed in all patients treated by FloSeal, compared to 1.3% and 2.7% of hemorrhage respectively in PPH and STARR patients treated without sealant. Post-operative pain was less severe in patients treated by FloSeal, without a difference statistically significant. The data are preliminary and must be confirmed in prospective randomized trials in larger series.
authors: Prima Facoltà di Medicina e Chirurgia, Dipartimento di Scienze Chirurgiche, UOC Chirurgia Generale L, Università degli Studi "La Sapienza", Roma.
authors: M
authors: M
authors: Mongardini
authors: F
authors: F
authors: Custureri
authors: F
authors: F
authors: Schillaci
authors: A
authors: A
authors: Cola
authors: A
authors: A
authors: Maturo
authors: G
authors: G
authors: Fanello
authors: S
authors: S
authors: Corelli
authors: G
authors: G
authors: Pappalardo
mesh_terms: D000328:Adult; D000368:Aged; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006484:Hemorrhoids / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control*; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D012005:Rectal Prolapse / Q000601:surgery*; D012189:Retrospective Studies; D017792:Surgical Stapling / Q000379:methods; D016896:Treatment Outcome