title: [Silicone occlusive sheeting vs silicone cushion for the treatment of hypertrophic and keloid scars. A prospective-randomized study].
abstract: BACKGROUND
  Silicone gel and silicone occlusive sheeting are widely used at present for the treatment of hypertrophic and keloid scars. In recent studies the possibility was raised that static electricity generated by friction activated silicone sheeting could be the reason for this effect, and that it can, with time, cause involution of hypertrophic and keloid scars. Objective of this study was to test this hypothesis and to observe weather a continuous and also an increased negatively charged static electric field will shorten the treatment period. A silicone cushion was developed with the purpose of increasing a negative static-electric charge to accelerate the regression process.
  
  
  METHODS
  From November 2001 to June 2002 we studied in a prospective randomized study, 72 patients with hypertrophic an keloid scars. The trial extended over a 8-month period. 37 patients underwent silicone occlusive sheeting, the remaining 35 patients underwent silicone cushion (Clinicel).
  
  
  RESULTS
  Treatment with the silicone cushions yielded 74,2% cessation of itching and burning followed by pallor and flattening of the scar, some markedly so, over a few weeks to 5 months period. Additional 25,7% had their scars resolved in up to 8 months of treatment. Four patients (11,4%) who add recalcitrant scars with little response to the use of the silicone cushion were given intralesional corticosteroid injections, in addiction to the use of the cushion, resulting in a fairly rayed resolution of these scars over a period of 2 months. Treatment with the silicone occlusive sheeting yielded 52,3% itching and burning cessation followed by pallor and flattening of the scar, some markedly so, over a few weeks to 5 months period. Additional 22,1% had their scars resolved in up to 8 months of treatment. In conclusion by comparing the results of this trial using silicone cushions for the treatment of hypertrophic and keloid scars with those obtained using silicone gel or occlusive sheeting, a much faster response was demonstrated.
authors: Dipartimento di Scienze Chirurgiche Università degli Studi di L'Aquila.
authors: G
authors: G
authors: Amicucci
authors: M
authors: M
authors: Schietroma
authors: M
authors: M
authors: Rossi
authors: C
authors: C
authors: Mazzotta
mesh_terms: D017439:Cicatrix, Hypertrophic / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D007627:Keloid / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D011446:Prospective Studies; D020034:Silicone Gels / Q000627:therapeutic use; D012827:Silicone Oils / Q000627:therapeutic use*
chemical_list: D020034:Silicone Gels; D012827:Silicone Oils