title: Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases.
abstract: Myxofibrosarcoma or myxoid malignant fibrous histiocytoma is one of the most common fibroblastic sarcomas in older patients. It is characterized by a tendency for predominantly subcutaneous, multinodular, diffusely infiltrative growth, which may extend to the overlying dermis and present as a cutaneous lesion. Histologically, it comprises a spectrum ranging from hypocellular low-grade myxoid to high-grade pleomorphic sarcoma. Because the dermal presentation usually appears relatively banal, accurate diagnosis is sometimes challenging. In this report, we present two cases of myxofibrosarcoma with dermal involvement.
authors: Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan. fujimura@gonryo.med.tohoku.ac.jp
authors: Taku
authors: T
authors: Fujimura
authors: Ryuhei
authors: R
authors: Okuyama
authors: Tadashi
authors: T
authors: Terui
authors: Kousei
authors: K
authors: Okuno
authors: Akiko
authors: A
authors: Masu
authors: Takashi
authors: T
authors: Masu
authors: Shuko
authors: S
authors: Chiba
authors: Takahide
authors: T
authors: Kunii
authors: Hachiro
authors: H
authors: Tagami
authors: Setsuya
authors: S
authors: Aiba
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D009077:Mucins / Q000032:analysis; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D009077:Mucins