title: Follow-up of children and adolescents with short stature: the importance of the growth rate.
abstract: OBJECTIVE
  Short stature is defined as a height of more than two standard deviations below the average for a given age and sex in a reference population. The objective was to describe follow-up conducted among short-stature children and adolescents.
  
  
  METHODS
  Descriptive study, at the Growth outpatient clinic, Department of Pediatrics, Universidade Federal de São Paulo.
  
  
  METHODS
  The study included 152 patients aged 2 to 15 years who had height for age of less than P5, on the National Center for Health Statistics curve. The children underwent nutritional evaluation, and several variables relating to height and growth rate were calculated to establish etiological diagnosis. Bone age was evaluated by X-ray.
  
  
  RESULTS
  The majority (63.2%) were male. In 77.8%, the stature observed was within the family pattern. Among the 99 patients followed up for more than 6 months, 17.2% presented inadequate growth rates. The preponderant etiological diagnosis for short stature was familial/constitutional in 58.6% of the cases; 27 patients (34.2%) with adequate growth rate presented bone age alterations. Even with inadequate growth rates, 75% of such patients had a normal result from growth hormone stimulation testing. Close to 90% of patients with a diagnosis of short stature of familial/constitutional origin and intrauterine growth retardation presented adequate growth rate. The genetic etiology was significantly characteristic of patients with inadequate growth rate.
  
  
  CONCLUSIONS
  Growth rate assessment must form part of the investigation and follow-up of short-stature cases. However, its utilization and validity should form part of an overall view of each patient.
authors: Department of Pediatrics, Universidade Federal de São Paulo, São Paulo, Brazil. rostrufaldi@directnet.com.br
authors: Maria Wany Louzada
authors: MW
authors: Strufaldi
authors: Edina Mariko Koga da
authors: EM
authors: Silva
authors: Rosana Fiorini
authors: RF
authors: Puccini
mesh_terms: D000293:Adolescent; D000365:Age Determination by Skeleton; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D009752:Nutritional Status; D010348:Patient Care Team