title: Continuous, intra-articular infusion of bupivacaine after total-knee arthroplasty may lead to potentially toxic serum levels of local anesthetic.
authors: Mark A
authors: MA
authors: Hoeft
authors: James P
authors: JP
authors: Rathmell
authors: Michael R
authors: MR
authors: Dayton
authors: Peter
authors: P
authors: Lee
authors: James G
authors: JG
authors: Howe
authors: Stephen J
authors: SJ
authors: Incavo
authors: John F
authors: JF
authors: Lawlis
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage*; D019645:Arthroplasty, Replacement, Knee; D002045:Bupivacaine / Q000008:administration & dosage* / Q000009:adverse effects / Q000097:blood; D006801:Humans; D007270:Injections, Intra-Articular; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine