Pharmacokinetics, bioequivalence, and spray weight reproducibility of intranasal butorphanol after administration with 2 different nasal spray pumps.
Wermeling
Daniel P
DP
College of Pharmacy, University of Kentucky, 725 Rose Street, Lexington, KY 40536-0082, USA.
Miller
Jodi L
JL
Archer
Sanford M
SM
Rayens
Mary K
MK
Rudy
Anita C
AC
D000281:Administration, Intranasal; D000328:Adult; D000336:Aerosols; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D019540:Area Under Curve; D002077:Butorphanol / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D016503:Drug Delivery Systems / Q000295:instrumentation; D005260:Female; D006207:Half-Life; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D013810:Therapeutic Equivalency
D000336:Aerosols; D000701:Analgesics, Opioid; D002077:Butorphanol