Daturacin, a new withanolide from Datura innoxia.
The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments.
Siddiqui
Bina S
BS
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, and Dr. Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Karachi-75270 Pakistan. bina@khi.comsats.net.pk
Arfeen
Shamsul
S
Begum
Sabira
S
Sattar
Fouzia A
FA
D032302:Datura / Q000737:chemistry*; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D012997:Solvents / Q000737:chemistry
D012997:Solvents; C504178:daturacin; D000432:Methanol; D004875:Ergosterol