title: Genetic evidence for the Mongolian ancestry of Kalmyks.
abstract: The Kalmyks are an ethnic group along the lower Volga River in Russia who are thought to have migrated there from Mongolia about 300 years ago. To investigate their origins, we studied mtDNA and Y-chromosome variation in 99 Kalmyks. Both mtDNA HV1 sequences and Y-chromosome SNP haplogroups indicate a close relationship of Kalmyks with Mongolians. In addition, genetic diversity for both mtDNA and the Y chromosome are comparable in Kalmyks, Mongolians, and other Central Asian groups, indicating that the Kalmyk migration was not associated with a substantial bottleneck. The so-called "Genghis Khan" Y-chromosome short tandem repeat (STR) haplotype was found in high frequency (31.3%) among Kalmyks, further supporting a strong genetic connection between Kalmyks and Mongolians. Genetic analyses of even recent, relatively well-documented migrations such as of the Kalmyks can therefore lead to new insights concerning such migrations.
authors: Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D-04103 Leipzig, Germany. nasidze@eva.mpg.de
authors: Ivan
authors: I
authors: Nasidze
authors: Dominique
authors: D
authors: Quinque
authors: Isabelle
authors: I
authors: Dupanloup
authors: Richard
authors: R
authors: Cordaux
authors: Lyudmila
authors: L
authors: Kokshunova
authors: Mark
authors: M
authors: Stoneking
mesh_terms: D044466:Asian People / Q000208:ethnology / Q000235:genetics* / Q000266:history*; D041322:Chromosomes, Human, Y / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics; D004641:Emigration and Immigration / Q000266:history*; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population / Q000379:methods; D006239:Haplotypes / Q000235:genetics; D049669:History, 16th Century; D049670:History, 17th Century; D006801:Humans; D008297:Male; D008986:Mongolia / Q000208:ethnology; D012426:Russia / Q000453:epidemiology
chemical_list: D004272:DNA, Mitochondrial