title: Age-dependent increases of calcium and phosphorus in human epiglottal cartilage.
abstract: To elucidate compositional changes of the elastic cartilage with aging, the authors investigated age-related changes of elements in the epiglottal cartilages by inductively coupled plasma-atomic emission spectrometry. After the ordinary dissection by medical students at Chiang Mai University was finished, the epiglottises were resected from the subjects. The epiglottal cartilages were isolated and the element contents were determined. The subjects consisted of 11 men and 14 women, ranging in age from 39 to 92 yr old. It was found that although the extent of accumulation of calcium and phosphorus was slight, calcium and phosphorus increased progressively in the epiglottal cartilages with aging. In contrast, sulfur, magnesium, zinc, iron, and sodium did not change significantly in them. Regarding the relationships among elements, it was found that there were significant correlations among calcium, phosphorus, magnesium, and sodium in the epiglottal cartilages, with one exception between calcium and sodium contents. In comparison between men and women, no significant differences were found in the predominant elements such as calcium, sulfur, and phosphorus in the epiglottal cartilages.
authors: Laboratory of Cell Biology, Department of Anatomy, School of Medicine, Nara Medical University, Kashihara, Nara 634-8521, Japan.
authors: Cho
authors: C
authors: Azuma
authors: Setsuko
authors: S
authors: Tohno
authors: Pasuk
authors: P
authors: Mahakkanukrauh
authors: Yoshiyuki
authors: Y
authors: Tohno
authors: Nutcharin
authors: N
authors: Ongkana
authors: Takeshi
authors: T
authors: Minami
authors: Yumi
authors: Y
authors: Moriwake
authors: Tsukasa
authors: T
authors: Kumai
authors: Pidhyasak
authors: P
authors: Vaidhayakarn
authors: Masa-oki
authors: MO
authors: Yamada
authors: Hirohisa
authors: H
authors: Maruyama
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D002118:Calcium / Q000378:metabolism*; D002356:Cartilage / Q000378:metabolism*; D004825:Epiglottis / Q000378:metabolism*; D005260:Female; D006801:Humans; D007501:Iron / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism*; D012737:Sex Factors; D012964:Sodium / Q000378:metabolism; D013054:Spectrophotometry, Atomic; D013455:Sulfur / Q000378:metabolism; D015032:Zinc / Q000378:metabolism
chemical_list: D010758:Phosphorus; D013455:Sulfur; D012964:Sodium; D007501:Iron; D008274:Magnesium; D015032:Zinc; D002118:Calcium