Noonan syndrome in a premature infant with hypertrophic cardiomyopathy and death in infancy.
We report an extremely premature infant with Noonan syndrome who developed rapidly progressive obstructive hypertrophic cardiomyopathy, which contributed to the death of the infant. The complications of prematurity combined with progressive, severe hypertrophic cardiomyopathy associated with Noonan syndrome lead to a poor prognosis.
Gibson
William
W
Department of Medical Genetics, Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada.
Trevenen
Cynthia
C
Giuffre
Michael
M
Leung
Alexander K C
AK
D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases; D008297:Male; D009634:Noonan Syndrome / Q000150:complications*