title: Selective ovarian vein sampling to localize a Leydig cell tumor.
abstract: OBJECTIVE
  To describe a patient with recent onset of rapidly progressive virilization who was diagnosed with an androgen-secreting tumor of the left ovary, localized by selective ovarian vein catheterization and hormonal sampling (SOVHS).
  
  
  METHODS
  Case report.
  
  
  METHODS
  Tertiary community-based medical center.
  
  
  METHODS
  A 32-year-old woman presenting with progressive virilization over a period of 4 months was found to have a Leydig cell tumor of the left ovary.
  
  
  METHODS
  Transvaginal ultrasound of the pelvis, followed by contrast-enhanced computerized tomography of the abdomen and the pelvis. Selective ovarian vein sampling was performed to localize the tumor. Laparoscopic left salpingo-oophorectomy and washings were also performed.
  
  
  METHODS
  Initial serum total T levels were 1,505 ng/dL, and the free serum T levels were 234 ng/dL. After SOVHS, the total serum T levels in the left ovarian vein is reported to be 20,967 ng/dL, and in the right ovarian vein, they were reported to be 1,351 ng/dL. Three months after laparoscopic left oophorectomy, the serum total T levels were 11 ng/dL. Institutional review board approval was obtained.
  
  
  RESULTS
  Patient's ovarian tumor removed laparoscopically was reported to be a Leydig cell tumor. Rapid decreases in free and total T followed tumor removal.
  
  
  CONCLUSIONS
  Selective ovarian vein catheterization and hormonal sampling is an effective diagnostic modality that can help localize small ovarian tumors.
authors: Department of Obstetrics and Gynecology, Dallas, Texas, USA.
authors: Ryan D
authors: RD
authors: Dickerson
authors: Michael J
authors: MJ
authors: Putman
authors: Michael E
authors: ME
authors: Black
authors: Karen R
authors: KR
authors: Pinto
authors: Norman G
authors: NG
authors: Diamond
authors: Samuel
authors: S
authors: Marynick
authors: Anil B
authors: AB
authors: Pinto
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000097:blood / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis*; D010053:Ovary / Q000098:blood supply*; D014680:Veins