title: Adrenalectomy for solitary adrenal metastases from non-small cell lung cancer.
abstract: BACKGROUND
  The treatment of patients with adrenal metastases from lung cancer (non-small cell lung cancer, NSCLC) remains controversial. Several studies of adrenalectomy in cases of isolated adrenal metastases from NSCLC suggest that these patients could have improved survival. Our aim is to define the history of patients after resection of solitary metastases to the adrenal gland and to identify characteristics of patients who achieved prolonged survival.
  
  
  METHODS
  Between January 1997 and July 2000, 11 patients underwent curative resection for metastatic NSCLC of the adrenal gland in our institution. In all patients who were accepted for curative adrenalectomy, the primary NSCLC had been treated by complete resection.
  
  
  RESULTS
  Eleven patients (seven men and four women) with unilateral adrenal metastases of NSCLC entered the study. Median age was 59 years (range 47-67 years). There was no perioperative death. The overall median survival after metastasectomy was 12.6 months (CI: 9.2-16.1 months). Patients with curative resection and metachronous disease (n=6) had a median survival of 30.9 months and tended to do better than patients with synchronous adrenal metastases (n=5) (median survival: 10.3 months).
  
  
  CONCLUSIONS
  We conclude that adrenalectomy for clinically solitary, resectable metastases can be performed safely. It appears reasonable that such selected patients should be considered surgical candidates.
authors: Department of Thoracic Surgery, Thoraxklinik Heidelberg, Amalienstr. 5, D-69126 Heidelberg, Germany. joachim.pfannschmidt@thoraxklinik-heidelberg.de
authors: Joachim
authors: J
authors: Pfannschmidt
authors: Bettina
authors: B
authors: Schlolaut
authors: Thomas
authors: T
authors: Muley
authors: Hans
authors: H
authors: Hoffmann
authors: Hendrik
authors: H
authors: Dienemann
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary* / Q000601:surgery*; D000315:Adrenalectomy; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary* / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies