[Modified sanjiasan decoction in regulating intelligence state of patients with vascular dementia].
OBJECTIVE
To investigate the therapeutic effects of modified Sanjiasan decoction (MSD) on vascular dementia (VD).


METHODS
Thirty-seven patients in the treated group were given MSD, one dosage each day, and 31 patients in the control group were administered orally Naofukang 0.8 g three times a day. The treatment course for both groups was three months. The indices as Hasegawa dementia scale (HDS), mini mental state examination (MMSE) and its subentries, intelligence quotient (IQ) and memory quotient (MQ) were examined.


RESULTS
MSD could improve the scores of HDS, MMSE and its subentries (P<0.05 or P<0.01), ameliorate dementia state and enhance IQ (P<0.05) and MQ (P<0.01) in patients with VD.


CONCLUSIONS
MSD has a certain effect on intelligence benefiting and dementia antagonizing.
Liu
Tao
T
Nanjing University of Traditional Chinese Medicine, Nanjing. liutao@njutcm.edu
Wang
Can-hui
CH
Yang
Jin
J
D000368:Aged; D015140:Dementia, Vascular / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007360:Intelligence / Q000187:drug effects*; D007361:Intelligence Tests; D008297:Male; D008419:Materia Medica / Q000627:therapeutic use; D008875:Middle Aged; D018697:Nootropic Agents / Q000627:therapeutic use; D008517:Phytotherapy
D008419:Materia Medica; D018697:Nootropic Agents