Vasopressin infusion in children with catecholamine-resistant septic shock.
OBJECTIVE
To describe use of vasopressin infusion for catecholamine-refractory septic shock in children.


METHODS
We report successful use of vasopressin infusion in three children with septic shock, in whom hypotension and poor perfusion persisted despite use of multiple infusions of vasopressors and inotropes.


RESULTS
All three had a rapid improvement in hypotension and perfusion after starting vasopressin infusion, allowing tapering of other infusions. Two children recovered completely.


CONCLUSIONS
Vasopressin appears to be useful in treatment of catecholamine-refractory septic shock in children.
Vasudevan
A
A
Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Lodha
R
R
Kabra
S K
SK
D000293:Adolescent; D002395:Catecholamines / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D012772:Shock, Septic / Q000503:physiopathology; D017211:Treatment Failure; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014667:Vasopressins / Q000627:therapeutic use*
D002395:Catecholamines; D014662:Vasoconstrictor Agents; D014667:Vasopressins