Moving primate genomics beyond the chimpanzee genome.
The comparative DNA sequence data that already exist on individual genomic loci depict the phylogenetic relationships of nearly all extant primate genera. Such a phylogenetic representation of the primates, validated by many sequenced primate genomes, and encompassing the full adaptive diversity of the order, is a prerequisite for identifying the genetic basis of humankind, and for testing the proposed human uniqueness of these traits. Some of these traits have been discovered recently, particularly in genes encoding proteins that are important for brain function.
Goodman
Morris
M
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. mgoodwayne@aol.com
Grossman
Lawrence I
LI
Wildman
Derek E
DE
D000818:Animals; D019295:Computational Biology; D019143:Evolution, Molecular; D014644:Genetic Variation; D016678:Genome; D006801:Humans; D002679:Pan troglodytes / Q000235:genetics; D010802:Phylogeny; D011323:Primates / Q000145:classification / Q000235:genetics*