The relationship of clinical response, oocyte number, and success in oocyte donor cycles.
OBJECTIVE
The purpose of the study was to determine if there is a threshold of clinical response to ovarian stimulation below which pregnancy rates diminish in oocyte donation cycles.


METHODS
Two hundred and seventy-six oocyte donor cycles were reviewed. Data were stratified by number of oocytes retrieved and divided into pregnant versus non-pregnant outcomes.


RESULTS
There were no differences in fertilization rates or clinical pregnancy rates regardless of the number of oocytes retrieved ranging from 3 to > 25. There was no difference in the mean age of the donors in pregnant versus non-pregnant cycles.


CONCLUSIONS
These data suggest that a lower threshold below which cycle cancellation should be considered donation cycles is different than standard IVF.
Letterie
Gerard
G
Center for Fertility and Reproductive Endocrinology, Virginia Mason Medical Center, Seattle, Washington, USA. chowletterie@comcast.com
Marshall
Lorna
L
Angle
Marlane
M
D000328:Adult; D005260:Female; D006801:Humans; D018587:Oocyte Donation; D009865:Oocytes / Q000254:growth & development*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies