New histopathological classification of actinic keratosis (incipient intraepidermal squamous cell carcinoma).
Actinic keratoses are common, sun-induced lesions that have historically been regarded as "premalignant." Evidence supports their inclusion along a continuum with squamous cell carcinoma. We propose a classification analogous to that used for cervical intraepithelial neoplasia.
Cockerell
Clay J
CJ
Dermatology and Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Wharton
James R
JR
D002294:Carcinoma, Squamous Cell / Q000145:classification* / Q000473:pathology*; D006801:Humans; D007642:Keratosis / Q000145:classification* / Q000473:pathology*; D012878:Skin Neoplasms / Q000145:classification* / Q000473:pathology*