Subanesthetic ketamine: how it alters physiology and behavior in humans.
Ketamine is a drug that is commonly used for anesthesia and analgesia worldwide. Although it has an excellent safety profile, cognitive and psychotomimetic adverse effects are commonly associated with its administration. This review describes the clinical applications, potential adverse events, neurobiological, and behavioral effects of ketamine used at subanesthetic doses in humans.
Rowland
Laura M
LM
Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA. lrowland@mprc.umaryland.edu
D001519:Behavior / Q000187:drug effects*; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D003071:Cognition / Q000187:drug effects*; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D007858:Learning / Q000187:drug effects; D008568:Memory / Q000187:drug effects
D018691:Excitatory Amino Acid Antagonists; D007649:Ketamine