title: [Regulation of tumor malignancy by inhibitors of posttranslational modification of Ras and Rho family proteins].
authors: Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
authors: Masaya
authors: M
authors: Imoto
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors; D000970:Antineoplastic Agents / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004164:Diphosphonates / Q000494:pharmacology; D015195:Drug Design; D004987:Ethers / Q000494:pharmacology; D051231:Farnesyltranstransferase; D006801:Humans; D015335:Molecular Probes; D005810:Multigene Family; D009369:Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors; D017368:Protein Prenylation / Q000187:drug effects; D018631:ras Proteins / Q000378:metabolism / Q000502:physiology*; D020741:rho GTP-Binding Proteins / Q000378:metabolism / Q000502:physiology*
chemical_list: C477902:4-carboxy-5,5'-dihydroxy-3,3'-dimethyl-diphenylether; D000970:Antineoplastic Agents; D001713:Biphenyl Compounds; D004164:Diphosphonates; D004987:Ethers; D015335:Molecular Probes; D019883:Alkyl and Aryl Transferases; C083291:geranylgeranyltransferase type-I; D051231:Farnesyltranstransferase; D010744:Phosphoric Monoester Hydrolases; C438007:prenyl-pyrophosphatase; D018631:ras Proteins; D020741:rho GTP-Binding Proteins