[Treatment of recurrent vulvovaginal candidosis with mycosyst (fluconazole)].
The authors treat 15 women with recurrent vulvovaginal candidosis with 3 sequential oral 150-mg doses of fluconazole (Mycosys, Gedeon Richter), each dose administered 72 hours after the first dose. Candida albicans was isolated in 14 women and Candida glabrata--in one. 14 days later all women had no clinical signs of vulvovaginal candidosis. Three months after the treatment only 11 women consulted for a checking exam--and all of them without clinical complaints, though in three of them (73.3%) C. albicans was isolated from the vaginal discharge. The authors discuss the difficulties in the treatment of recurrent vulvovaginal candidosis and the advantages of the sequential type of therapy with fluconazole.
Pekhlivanov
B
B
Amaliev
I
I
Ivancheva
Kh
Kh
Zisova
L
L
D000282:Administration, Intravaginal; D000284:Administration, Oral; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002176:Candida albicans / Q000302:isolation & purification; D041221:Candida glabrata / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D004334:Drug Administration Schedule; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D055502:Secondary Prevention; D016896:Treatment Outcome
D000935:Antifungal Agents; D015725:Fluconazole