Chronic tick-borne encephalitis virus antigenemia: possible pathogenesis pathways.
Study of the proliferative potential and immunophenotype of lymphocytes and cytokine-producing capacity of mononuclear cells in patients with chronic tick-borne encephalitis virus antigenemia showed changes in T cell lymphoproliferative response, relative content of T cells and T helper inductors, immunoregulatory index, and imbalance in the production of immunoregulatory Th1 and Th2 cytokines.
Naslednikova
I O
IO
Department of Pathophysiology, Department of Fundamentals of Clinical Medicine, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. ira_naslednikova@mail.ru
Ryazantseva
N V
NV
Novitskii
V V
VV
Lepekhin
A V
AV
Antoshina
M A
MA
Belokon
V V
VV
Tomson
Yu V
YV
D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000097:blood*; D002908:Chronic Disease; D004675:Encephalitis, Tick-Borne / Q000276:immunology*; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D008297:Male; D008875:Middle Aged
D000956:Antigens, Viral