Leukemic infiltration of the orbit: report of three cases and literature review.
Orbital infiltration by acute lymphoblastic leukemia is rare. The authors present 3 patients, 2 with optic nerve involvement and 1 with anterior chamber infiltration, treated by chemotherapy and radiotherapy. Two are in continuous remission at 64 and 59 months and 1 relapsed in the central nervous system 35 months after ocular relapse. Visual deterioration was prevented in two. Early diagnosis and treatment are important for preservation of vision.
Taylor
C W
CW
Cookridge Hospital, Leeds, United Kingdom. Roger.Taylor@Leedsth.nhs.uk
Taylor
R E
RE
Kinsey
S E
SE
D002675:Child, Preschool; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D017254:Leukemic Infiltration / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008297:Male; D009364:Neoplasm Recurrence, Local; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed