[Anal squamous cell carcinoma synchronous with rectal adenocarcinoma].
Most often colorectal carcinoma occurs single; synchronous multiple carcinomas usually develop at widely disparate sites. We report the case of a 75-year-old male, accusing rectal bleeding, disturbances in bowel transit and weight loss. The rectoscopy examination revealed a fungating, bleeding tumor located 5 cm from anal verge. Pathological diagnostic of the endo-biopsy was ulcerated moderate differentiated adenocarcinoma. Patient underwent surgical amputation of the rectum with lymphadenectomy. Microscopical examination of the surgical specimens confirmed the presence of the adenocarcinoma adjacent to a squamous cell carcinoma, moderate differentiated, with reduced keratinization, infiltrative. Also, 2 from the 7 lymph nodes presented squamous cell carcinoma metastases. The most important differential diagnostic is a rectal adenosquamous carcinoma. Prognostic depends on stage of the disease, generally being worse than of the corresponding adenocarcinoma, and can be improved by radio- and chemotherapy.
Danciu
M
M
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi Facultatea de Medicină, Disciplina Morfopatologie, Spitalul Clinic Judeţean de Urgenţă Sf. Spiridon Iaşi.
Ferariu
D
D
Teleman
S
S
Mihailovici
Maria-Sultana
MS
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000368:Aged; D001005:Anus Neoplasms / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery