Two-photon absorption and self-phase modulation measurements with shaped femtosecond laser pulses.
We show that phase-sensitive detection of spectral hole refilling can yield information about self-phase modulation and two-photon absorption coefficients. We expect that, when applied to tissue microscopy, this technique will allow the study of endogenous molecular markers beneath the surface, even if those markers are nonfluorescent.
Fischer
Martin C
MC
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Ye
Tong
T
Yurtsever
Gunay
G
Miller
Anthony
A
Ciocca
Maria
M
Wagner
Wolfgang
W
Warren
Warren S
WS
D000465:Algorithms; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007834:Lasers; D036641:Microscopy, Fluorescence, Multiphoton / Q000379:methods*; D012235:Rhodamines / Q000032:analysis*
D012235:Rhodamines