title: Correlation of reactive oxygen species levels with the fertilization rate after in vitro fertilization: a qualified meta-analysis.
abstract: Our meta-analysis analyzed the relationship between levels of reactive oxygen species (ROS) and fertilization rate after in vitro fertilization (IVF), and showed a statistically significant correlation between the ROS levels and the IVF fertilization rate (estimated overall correlation -0.374 [95% CI, -0.520, -0.205]). We conclude that ROS has a statistically significant effect on the fertilization rate after IVF, and that the measurement of ROS levels in semen specimens before IVF may be useful in predicting the IVF outcome and in counseling patients.
authors: Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute, Department of Obstetrics-Gynecology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA. agarwaa@ccf.org
authors: Ashok
authors: A
authors: Agarwal
authors: Shyam S R
authors: SS
authors: Allamaneni
authors: Kiran P
authors: KP
authors: Nallella
authors: Amanda T
authors: AT
authors: George
authors: Edward
authors: E
authors: Mascha
mesh_terms: D016001:Confidence Intervals; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D007246:Infertility / Q000378:metabolism*; D008297:Male; D017382:Reactive Oxygen Species / Q000032:analysis / Q000378:metabolism*; D012044:Regression Analysis
chemical_list: D017382:Reactive Oxygen Species