[Influence of combined spinal-epidural analgesia and epidural analgesia on the progress of labor].
OBJECTIVE
To investigate the influence of combined spinal-epidural analgesia (CSEA) and epidural analgesia (EA) and patient-controlled epidural analgesia (PCEA) on labor progress.


METHODS
The partograms of 722 healthy vaginal delivery nulliparas were retrospectively analyzed in Department of Obstetric and Gynecology, First Hospital of Peking University. Three groups were divided among all subjects: CSEA group (259 cases) receiving CSEA + PCEA, EA group (215 cases) receiving EA + PCEA and control group (248 cases) without any analgesia method.


RESULTS
The duration of active phase in the first stage and the second stage in the CSEA group [(272 +/- 127) min and (57 +/- 36) min] and in the EA group [(305 +/- 133) min and (59 +/- 39) min] were significantly longer than that of control group [(188 +/- 110) min and (45 +/- 32) min]. No significant difference was found in the three groups in the duration of the third stage [CSEA: (9 +/- 6) min; EA: (8 +/- 6) min;


METHODS
(9 +/- 6) min. P > 0.05]. The dilatation curve of the cervix in CSEA group and EA group was plotted on the right side of the Friedman curve while that of the control group on the left, reflecting a slower progress in the former two groups than the control during the active phase. The average speed of cervical dilatation in CSEA and EA groups (1.5 cm and 1.4 cm) was significantly slower than that of the control (1.8 cm) in the active phase (P < 0.01).


CONCLUSIONS
CSEA + PCEA or EA + PCEA during labor might slow down the progress of the active phase and lead to a prolonged labor in the end. Therefore, the management of these parturients may vary based on Friedman partogram.
Zhang
Miao
M
Department of Obstetric and Gynecology, First Hospital of Peking University, Beijing 100034, China.
Yang
Hui-xia
HX
Li
Hai-yan
HY
Shi
Hui-xing
HX
Qu
Yuan
Y
D000328:Adult; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000700:Analgesics / Q000008:administration & dosage*; D000775:Anesthesia, Spinal; D005260:Female; D006801:Humans; D048949:Labor Pain / Q000188:drug therapy*; D007743:Labor, Obstetric / Q000187:drug effects*; D011247:Pregnancy; D012189:Retrospective Studies; D055815:Young Adult
D000700:Analgesics