[A case of meningeal carcinomatosis due to the ethmoid sinus mucoepidermoid carcinoma].
We report here a 65-year-old man with ptosis, diplopia, and progressive lower limb muscle weakness without nasal symptoms. CA19-9 and CEA were elevated in the serum and cerebrospinal fluid (CSF), but Squamous Cell Carcinoma Antigen (SCC) was not. CA19-9-positive atypical cells were found in the CSF. A right ethmoidal tumor was discovered by paranasal CT and 18F-Deoxyglucose Positron Emission Tomography (FDG-PET) studies. The ethmoidal tumor invaded to the orbits and disseminated into the CSF space through the cribriform plate. Biopsy demonstrated that the paranasal tumor consisted of mucoepidermoid carcinoma. We report here the first case of meningeal carcinomatosis due to mucoepidermoid carcinoma in the ethmoid sinus.
Hayashi
Yuichi
Y
Department of Neurology and Geriatrics, Division of Neuroscience, Gifu University Graduate School of Medicine.
Matsuyama
Zenjiro
Z
Murai
Michinori
M
Shimokawa
Kuniyasu
K
Amano
Yuhei
Y
Hashizume
Tatsuma
T
Nishida
Hiroshi
H
Hozumi
Isao
I
Inuzuka
Takashi
T
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D018395:CA-19-9 Antigen / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D018277:Carcinoma, Mucoepidermoid / Q000150:complications / Q000175:diagnosis*; D005005:Ethmoid Sinus; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000209:etiology*; D010255:Paranasal Sinus Neoplasms / Q000150:complications / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18