title: A degenerative encephalomyelopathy in 7 Kuvasz puppies.
abstract: Seven Kuvasz puppies from 2 same-parentage litters developed weakness and ataxia. Six necropsied dogs had lesions in caudate nucleus, cerebellar nuclei and folia, and spinal cord. Lesions seen were felt to be familial or due to the effects of an amprolium-induced thiamine deficiency on the developing brains of these puppies.
authors: Animal Health Laboratory, University of Guelph, Guelph, Ontario. mhazlett@uoguelph.ca
authors: Murray J
authors: MJ
authors: Hazlett
authors: Laura L
authors: LL
authors: Smith-Maxie
authors: Alexander
authors: A
authors: de Lahunta
mesh_terms: D000670:Amprolium / Q000633:toxicity*; D000818:Animals; D000831:Animals, Newborn; D000981:Antiprotozoal Agents / Q000633:toxicity*; D001259:Ataxia / Q000209:etiology / Q000662:veterinary; D001921:Brain / Q000473:pathology; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D008297:Male; D013116:Spinal Cord / Q000473:pathology; D013832:Thiamine Deficiency / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000981:Antiprotozoal Agents; D000670:Amprolium