title: [Interventricular management of patients over the age of 75 with acute coronary syndromes without persistent ST elevation].
abstract: The aim ot tnis study was to assess the results of interventional strategy in patients over 75 years of age admitted to hospital with acute coronary syndromes (ACS) without persistent ST elevation. Over three months, patients over the age of 75 undergoing coronary angiography for ACS were included in a multicentre register and followed up for 6 months. A total of 126 patients with an average age of 79 were included: 70% had at least one poor prognostic factor. The treatment on admission included: Aspirin (84%), Clopidogrel (60%), anti GpIIb-IIIa (12%) and Heparin (81%, of which 3/4 of cases were low molecular weight heparins). Coronary angiography (average delay 80 hours) showed single, double and triple vessel disease in 21, 29 and 35% of cases respectively. Coronary angioplasty was proposed in 83 patients and carried out in 82. Eleven patients underwent coronary artery bypass grafting and 31 were treated medically. During the hospital phase, there were 3 major cardiovascular complications: 1 death during coronary angiography, 1 intra-stent thrombosis and 1 death in the group undergoing bypass grafting, with no major bleeding complications. At 6 months, there were 8 (6.5%) major cardiovascular adverse events with 6 in the "angioplasty" group; 5 deaths (3 cardiac deaths), 3 myocardial infarcts. Two thirds of patients were asymptomatic. The authors conclude that interventional strategy in ACS of elderly patients is associated with a low rate of major adverse events. The benefits of this strategy should be confirmed by randomised trial.
authors: Département de cardiologie, centre cardiopneumologique CHU Rennes.
authors: A
authors: A
authors: Géhanne
authors: A
authors: A
authors: Shayne
authors: H
authors: H
authors: Eltchaninoff
authors: M
authors: M
authors: Gilard
authors: P
authors: P
authors: Richard
authors: G
authors: G
authors: Range
authors: J P
authors: JP
authors: Hacot
authors: E
authors: E
authors: Lefebvre
authors: R
authors: R
authors: Douillet
authors: A
authors: A
authors: Tirouvanziam
authors: H
authors: H
authors: Le Breton
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000009:adverse effects / Q000379:methods*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D011379:Prognosis; D015607:Stents; D013577:Syndrome; D016896:Treatment Outcome