Impact of finasteride treatment on perioperative bleeding before transurethral resection of the prostate: a prospective randomized study.
In this preliminary, randomized study, 35 men were pretreated for 3 months with finasteride or placebo before transurethral resection of the prostate. The study was inconclusive because it did not show any benefit in terms of reducing perioperative bleeding during or after the resection but there is a need for a large, prospective, randomized study.
Lund
Lars
L
Department of Urology, Viborg Hospital, Viborg, Denmark. Dr.LL@Dadlnet.dk
Møller Ernst-Jensen
Klaus
K
Tørring
Niels
N
Erik Nielsen
Jens
J
D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D018120:Finasteride / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects*; D011470:Prostatic Hyperplasia / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
D004791:Enzyme Inhibitors; D018120:Finasteride