Effect of granulocyte colony-stimulating factor on myocardium recovery in postinfarction period.
The effect of Neutrostim (preparation of granulocytic colony-stimulating factor) on recovery of myocardial tissue after acute myocardial infarction was studied in rats. A course of Neutrostim after ligation of the left coronary artery led to normalization of electrocardiographic and morphological parameters of the myocardium after one month.
Gol'dberg
E D
ED
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk.
Dygai
A M
AM
Zhdanov
V V
VV
Stavrova
L A
LA
Fomina
T I
TI
Plotnikov
M B
MB
Aliev
O I
OI
Chernyshova
G A
GA
Masycheva
V I
VI
Sotnikova
N V
NV
D000818:Animals; D003331:Coronary Vessels; D004562:Electrocardiography; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology / Q000627:therapeutic use*; D008026:Ligation; D008297:Male; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D009206:Myocardium / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D016179:Granulocyte Colony-Stimulating Factor