Impact of lifestyle on prevalence of kidney disease in Pima Indians in Mexico and the United States.
Pima Indians in the United States and Mexico share a common genetic background but have very different lifestyles. Comparisons were made of the frequency of obesity, diabetes, hypertension, and kidney disease in these geographically separated but susceptible populations. Mexican Pimas had higher levels of physical activity, less obesity, and a lower prevalence of diabetes than their US Pima counterparts. Mean blood pressure rose with worsening glucose tolerance, and the prevalence of elevated urinary albumin excretion was higher in patients with diabetes than in those without, regardless of whether they lived in the United States or Mexico. These findings illustrate the importance of lifestyle in the development of diabetes and in the subsequent occurrence of diabetic kidney disease.
Valencia
Mauro E
ME
Centro de Investigación en Alimentación y Desarrollo, AC Hermosillo, Sonora, Mexico. mauro@cascabel.ciad.mx
Weil
E Jennifer
EJ
Nelson
Robert G
RG
Esparza
Julian
J
Schulz
Leslie O
LO
Ravussin
Eric
E
Bennett
Peter H
PH
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000453:epidemiology; D003928:Diabetic Nephropathies / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007198:Indians, North American; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000453:epidemiology* / Q000473:pathology; D008019:Life Style; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors; D014481:United States / Q000453:epidemiology
D001786:Blood Glucose