Chronic renal failure in young Old English Sheepdogs.
Chronic renal failure was diagnosed in three young Old English Sheepdogs. Clinical signs were characterised by ill-thrift, polydipsia, polyuria, nervous signs and behavioural changes. Laboratory findings showed azotaemia, non-regenerative anaemia, hyperphosphataemia and isosthenuria. The kidneys were characterised histologically by interstitial fibrosis, and thickening and calcification of the tubular and glomerular basement membrane. A familial incidence could not be confirmed in these cases.
Jones
B R
BR
Department of Veterinary Clinical Sciences, Massey University, Palmerston North.
Jones
J M
JM
Chen
W
W
Cayzer
J
J