title: A review of selenium deficiency in grazing ruminants. Part 1: new roles for selenium in ruminant metabolism.
abstract: SELENIUM AVAILABILITY: Selenium deficiency has been an important source of loss to the pastoral industries of New Zealand. About 30% of farmed land in New Zealand is considered to be selenium-deficient and continued development of soils and pasture will tend to further decrease the concentration of selenium in pasture.
  Formerly it was believed that all biological functions of selenium in animals could be attributed to the antioxidant activity of the enzyme glutathione peroxidase. More recently, it has been shown that selenoproteins have roles in immune function and thyroid hormone metabolism.
  Following supplementation of ruminants grazing pastures deficient in selenium, milk production and growth responses are likely to occur in cattle, while in sheep improvements in growth and fertility are most likely. Reproductive dysfunction may not be as important as previously thought in cattle grazing pasture moderately deficient in selenium. The relationship between selenium intake and disease resistance deserves further study.
  
  
  CONCLUSIONS
  Management of selenium deficiency will continue to be important in grazing ruminants. Veterinarians should be aware that many selenoenzymes exist, some with functions quite distinct from the antioxidant role of glutathione peroxidase.
authors: Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada C1A 4P4. jwichtel@upei.ca
authors: J J
authors: JJ
authors: Wichtel