Meningiomas after radiation-therapy for benign astrocytomas.
A 4.5 year-old-girl was submitted to subtotal removal of a benign astrocytoma of the left temporal lobe with basal ganglia extension and given radiotherapy. At age 27, she was found to harbor a right posterior frontal meningioma that was totally removed. A recurrence of the right convexity meningioma was again excised after a 4-year interval. The authors report this case to illustrate the possibility of the appearance of radiation-induced meningiomas after an interval of 22 years and briefly discuss 16 previous reports on this occurrence in benign astrocytomas.
Martínez-Lage
J
J
Servicio Regional de Neurocirugía, Hospital Universitario Virgen de la Arrixaca, Murcia.
Ros de San Pedro
J
J
Martínez-Pérez
M
M
Poza
M
M
D001037:Aphasia / Q000209:etiology; D001254:Astrocytoma / Q000532:radiotherapy* / Q000601:surgery; D001479:Basal Ganglia / Q000601:surgery; D002675:Child, Preschool; D003399:Craniotomy; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000209:etiology* / Q000601:surgery; D008579:Meningioma / Q000209:etiology* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000601:surgery; D010291:Paresis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology; D018714:Radiotherapy, Adjuvant; D012640:Seizures / Q000209:etiology; D015173:Supratentorial Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D013702:Temporal Lobe / Q000601:surgery; D013997:Time Factors