Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: implications for gene identification.
A rapid route to gene molecular identification involves using recombination frequencies in locating mutational sequence changes. We describe a case where the recombination frequency is deceptively low, probably reflecting centromere proximity. Recombination frequencies are greatly reduced near the centromeres on the right arms of chromosomes III and IV of Aspergillus nidulans.
Espeso
Eduardo A
EA
Departamento de Microbiologia Molecular, Centro de Investigaciones Biologicas, CSIC, Madrid, Spain.
Cobeño
Laura
L
Arst
Herbert N
HN
D001233:Aspergillus nidulans / Q000235:genetics*; D001483:Base Sequence; D002503:Centromere / Q000235:genetics; D015825:Chromosomes, Fungal / Q000235:genetics*; D005800:Genes, Fungal / Q000235:genetics*; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D020161:Physical Chromosome Mapping; D011995:Recombination, Genetic / Q000235:genetics*; D017422:Sequence Analysis, DNA