[Preoperative care of microcirculatory vessels in patients with lower limb arteriosclerosis obliterans].
The paper analyses diagnosis and treatment outcomes for 20 men aged from 55 to 76 with lower limb arteriosclerosis obliterans. Based on exhaustive laboratory and instrumental diagnostic data the authors conclude that 10-days course of Vazaprostan (20 mkg per day) for patients with IIb stage of chronic lower limb arterial insufficiency yields not only improvement in tissue metabolism, but a reduction of peripheral vascular resistance as well. Thus such therapy can be used for preoperative care before reconstructive vascular interventions in order to reduce the risk of implant thrombosis in early postoperative period.
Kuznetsov
M R
MR
Koshkin
V M
VM
Karalkin
A V
AV
Boldin
B V
BV
Rodionov
S V
SV
Sergeeva
N A
NA
Petukhov
E B
EB
Golosnitskiĭ
P Iu
PIu
D000368:Aged; D000527:Alprostadil / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001162:Arteriosclerosis Obliterans / Q000188:drug therapy* / Q000601:surgery*; D001809:Blood Viscosity / Q000187:drug effects; D003131:Combined Modality Therapy; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply* / Q000601:surgery; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011300:Preoperative Care; D012212:Rheology; D012720:Severity of Illness Index
D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D000527:Alprostadil