Mirtazapine in drug-induced excessive sweating.
Excessive sweating is a well-known side effect of a selective serotonin reuptake inhibitor treatment, but little is known about the impact of sweating on treatment discontinuation or the general quality of life of patients. In this case report, we present a patient suffering from excessive sweating induced by escitalopram. When mirtazapine was administered as an additional treatment, a dose-dependent reduction of drug-induced excessive sweating was observed. Taking into account the particular serotonin antagonistic properties of mirtazapine, its eventual influence on the regulation of body temperature and diaphoresis in the central nervous system is discussed.
Buecking
Ansgar
A
University Department for Adult Psychiatrie, Lausanne, Switzerland. Ansgar.Buecking@chur.ch
Vandeleur
Caroline Louise
CL
Khazaal
Yasser
Y
Zullino
Daniele Fabio
DF
D015283:Citalopram / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives* / Q000494:pharmacology; D008875:Middle Aged; D000078785:Mirtazapine; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects*; D013546:Sweating / Q000187:drug effects*
D015283:Citalopram; D008803:Mianserin; D000078785:Mirtazapine; D017367:Selective Serotonin Reuptake Inhibitors