title: Perinatal outcome of blastocyst transfer with vitrification using cryoloop: a 4-year follow-up study.
abstract: OBJECTIVE
  To evaluate perinatal outcome of ultrarapid vitrified blastocyst transfer.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Private IVF clinics.
  
  
  METHODS
  One hundred eight women, who delivered 147 babies.
  
  
  METHODS
  Supernumerary blastocysts were vitrified using cryoloop method and transferred after warming.
  
  
  METHODS
  Survival rate of blastocyst after vitrification, implantation and pregnancy rates, neonatal outcome and congenital birth defects.
  
  
  RESULTS
  A total of 1,129 vitrified blastocysts from 435 cycles were warmed and 967 survived (85.7%). In 413 cycles of transfer, the pregnancy, implantation, and abortion rates were 44.1%, 29.0%, and 22.0%, respectively. Of 108 deliveries, 34 (32.9%) were multiple pregnancies and 20 were preterm (18.5%). Out of 147 children born, 50.3% were male and congenital birth defects were observed in 1.4%. These results were similar with those of fresh blastocyst transfer program.
  
  
  CONCLUSIONS
  The vitrification of blastocyst using cryoloop is a simple, easy, and quick method. This technique yields the same high pregnancy and implantation rates as fresh blastocyst transfer. Congenital defect rate in this study was similar to fresh blastocyst transfer, proving the method to be safe.
authors: Hiroshima HART Clinic, Nakaku, Hiroshima, Japan. hart@enjoy.ne.jp
authors: Katsuhiko
authors: K
authors: Takahashi
authors: Tetsunori
authors: T
authors: Mukaida
authors: Tetsuya
authors: T
authors: Goto
authors: Chikahiro
authors: C
authors: Oka
mesh_terms: D000328:Adult; D001755:Blastocyst / Q000502:physiology; D016009:Chi-Square Distribution; D015925:Cryopreservation / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data*; D004624:Embryo Transfer / Q000295:instrumentation / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018743:Perinatal Care / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies