[A case of portal vein thrombosis associated with acute pancreatitis and cholangitis].
Portal vein thrombosis is a rare complication accompanied with acute pancreatitis or cholangitis/cholecystitis. The main pathogenesis of portal vein thrombosis in pancreatitis or cholangitis/cholecystitis are suggested to be venous compression by pseudocyst and an imbalance between the blood coagulation and fibrinolysis. In this case report, we experienced a 63 year old male who developed portal vein thrombosis later in the course of the treatment of acute gallstone pancreatitis with cholangitis/cholecystitis without any symptom or sign. The diagnosis of portal vein thrombosis was given on follow up CT scan and serum protein S activity was decreased to 27% in laboratory study. Immediate anticoagulation therapy with heparin and thrombolytic therapy with urokinase and balloon dilatation were performed. Despite the aggressive treatment, complete reperfusion could not be obtained. With oral warfarin anticoagulation, the patient showed no disease progression and was discharged. We report a case of portal vein thrombosis as a complication of acute pancreatitis and cholangitis/cholecystitis with a review of literatures.
Cheung
Dae Young
DY
Division of Gastroenterology, Department of Internal Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Yeongdeungpo-gu, Seoul, Korea.
Kim
Jae Kwang
JK
Jo
Don Hyoun
DH
Oh
Hyun Jong
HJ
Kim
Tae Ho
TH
Lee
So Yeon
SY
Park
Soo Heon
SH
Han
Joon Yeol
JY
Chung
Kyu Won
KW
Sun
Hee Sik
HS
D000208:Acute Disease; D002761:Cholangitis / Q000150:complications* / Q000175:diagnosis; D002764:Cholecystitis / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications* / Q000175:diagnosis; D011169:Portal Vein; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology*