Immunogenicity and tolerability of hepatitis A vaccine in HIV-infected children.
The immunogenicity and tolerability of hepatitis A virus vaccine was evaluated in a group of 32 children with human immunodeficiency virus (HIV) infection and 27 children with seroreversion. After 2 doses of vaccine, 100% of children experienced seroconversion with good toleration of the vaccine. There were no differences in variation of virus load between immunized HIV-positive children and a group of 31 nonimmunized HIV-positive children with similar characteristics.
Gouvea
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Division of Pediatric Infectious Diseases, Federal University of São Paulo, São Paulo, Brazil.
De Moraes-Pinto
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Ono
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Dinelli
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Machado
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DM
Weckx
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Succi
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D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology*; D035922:Hepatitis A Antibodies / Q000096:biosynthesis* / Q000097:blood; D022362:Hepatitis A Vaccines / Q000008:administration & dosage / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance
D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines