A highly efficient palladacycle catalyst for hydrophenylation of C-, N-, and O-substituted bicyclic alkenes under aerobic condition.
A new phosphine-free palladacycle catalyst 4 was prepared from benzyl oxazoline in high yield and fully characterized. With it as catalyst, hydrophenylation reactions of a wide range of bicyclic alkenes, not only norbornene and norbornadiene but also oxa- and aza-bicyclic alkenes, with iodobenzene proceeded smoothly under aerobic condition without exclusion of water. Up to 1.7 x 10(6) TON as well as 1.2 x 10(5) TOF were achieved.
Yuan
Ke
K
State Key Laboratory of Organometallic Chemistry and Shanghai Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Zhang
Ting Ke
TK
Hou
Xue Long
XL