title: Effects of cholinergic receptor agonists and antagonists on miniature stimulatory postsynaptic ionic currents in somatic muscle cells of lumbricus terrestris.
abstract: Miniature stimulating postsynaptic currents of Lumbricus terrestris somatic muscle cells were recorded. Atropine, d-tubocurarin, alpha-bungarotoxin, carbacholine, and proserin did not modify the amplitude and temporal parameters of miniature stimulatory postsynaptic currents, while carbacholine and nicotine depolarized the muscle membrane. Presumably, Lumbricus terrestris muscle cells contain acetylcholine-sensitive channel-receptor complexes not belonging to classical nicotinic or muscarinic acetylcholine receptors.
authors: Kazan State Medical University. emvolkov@kzn.ru
authors: E M
authors: EM
authors: Volkov
authors: L F
authors: LF
authors: Nurullin
mesh_terms: D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002038:Bungarotoxins / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology; D018679:Cholinergic Agonists / Q000494:pharmacology*; D018680:Cholinergic Antagonists / Q000494:pharmacology*; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D032342:Muscle Cells / Q000502:physiology*; D009388:Neostigmine / Q000494:pharmacology; D009538:Nicotine / Q000494:pharmacology; D009835:Oligochaeta / Q000166:cytology / Q000502:physiology*; D011950:Receptors, Cholinergic / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology
chemical_list: D002038:Bungarotoxins; D018679:Cholinergic Agonists; D018680:Cholinergic Antagonists; D007473:Ion Channels; D011950:Receptors, Cholinergic; D009388:Neostigmine; D009538:Nicotine; D001285:Atropine; D002217:Carbachol; D014403:Tubocurarine