title: Functional near-infrared neuroimaging.
abstract: Functional near-infrared spectroscopy (fNIR) is a neroimaging modality that enables continuous, noninvasive, and portable monitoring of changes in blood oxygenation and blood volume related to human brain function. Over the last decade, studies in the laboratory have established that fNIR spectroscopy provides a veridical measure of oxygenation and blood flow in the brain. Our recent findings indicate that fNIR can effectively monitor cognitive tasks such as attention, working memory, target categorization, and problem solving. These experimental outcomes compare favorably with functional magnetic resonance imaging (fMRI) studies, and in particular, with the blood oxygenation level dependent signal. Since fNIR can be implemented in the form of a wearable and minimally intrusive device, it has the capacity to monitor brain activity under real life conditions and in everyday environments. Moreover, the fNIR system is amenable to integration with other established physiological and neurobehavioral measures, including electroencephalogram, eye tracking, pupil reflex, heart rate variability, respiration, and electrodermal activity.
authors: School of Biomedical Engineering, System and Health Systems, Drexel University, Philadelphia, PA 19104, USA. meltem@cbis.ece.drexel.edu
authors: Meltem
authors: M
authors: Izzetoglu
authors: Kurtulus
authors: K
authors: Izzetoglu
authors: Scott
authors: S
authors: Bunce
authors: Hasan
authors: H
authors: Ayaz
authors: Ajit
authors: A
authors: Devaraj
authors: Banu
authors: B
authors: Onaral
authors: Kambiz
authors: K
authors: Pourrezaei
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D006801:Humans; D009474:Neurons / Q000502:physiology*; D010100:Oxygen / Q000378:metabolism*; D013055:Spectrophotometry, Infrared / Q000295:instrumentation / Q000379:methods*
chemical_list: D010100:Oxygen