Diastereoselective reductive imino-aldol reaction of alpha-imino esters promoted by titanium tetraiodide: synthesis of alpha,beta-diamino esters.
Under the influence of titanium tetraiodide reductive imino-aldol reaction of the N-tosylimine derived from ethyl glyoxylate proceeded with aldimines to give alpha,beta-diamino esters in good yields in a highly diastereoselective manner.
Shimizu
Makoto
M
Department of Chemistry for Materials, Mie University, Tsu, Mie 514-8507, Japan. mshimizu@chem.mie-u.ac.jp
Inayoshi
Koji
K
Sahara
Tetsuya
T