title: Chondrodystrophy in calves associated with manganese deficiency.
abstract: A severe congenital chondrodystrophy in Charolais calves is described. Thirty-two calves were born on the same farm with shortened limbs and enlarged joints. Histologically, there was poor cartilage maturation with excessive amounts of rarefied cartilage matrix. There were degenerative changes in the chondrocytes and a severe reduction in the mucopolysaccharide content of all body hyaline cartilage. The cartilage matrix, when examined ultrastructurally, showed loose, disorganised fibres in a rarefied matrix, and extensive vacuolation of the chondrocytes. A low level of manganese was found in the liver of an affected calf. The pregnant cows were fed on apple pulp and corn silage, both of which are low in manganese.
authors: Departamento de Fisiopatologia, CENID-Microbiologia INIFAP-SARH, Km 15.5 carretera Mexico-Toluca, Mexico D.F. 05100, Mexico.
authors: G
authors: G
authors: Valero
authors: M R
authors: MR
authors: Alley
authors: L M
authors: LM
authors: Badcoe
authors: B W
authors: BW
authors: Manktelow
authors: M
authors: M
authors: Merrall
authors: G S
authors: GS
authors: Lawes