title: A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis.
abstract: A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.
authors: Institute of Legal Medicine, University of Santiago de Compostela, San Francisco s/n, 15782 Santiago de Compostela, Spain. brioniml@usc.es
authors: María
authors: M
authors: Brion
authors: Berit M
authors: BM
authors: Dupuy
authors: Marielle
authors: M
authors: Heinrich
authors: Carsten
authors: C
authors: Hohoff
authors: Bernardette
authors: B
authors: Hoste
authors: Bertrand
authors: B
authors: Ludes
authors: Bente
authors: B
authors: Mevag
authors: Niels
authors: N
authors: Morling
authors: Harald
authors: H
authors: Niederstätter
authors: Walther
authors: W
authors: Parson
authors: Juan
authors: J
authors: Sanchez
authors: Klaus
authors: K
authors: Bender
authors: Nathalie
authors: N
authors: Siebert
authors: Catherine
authors: C
authors: Thacker
authors: Conceiçao
authors: C
authors: Vide
authors: Angel
authors: A
authors: Carracedo
mesh_terms: D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005060:Europe; D005819:Genetic Markers; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D015203:Reproducibility of Results
chemical_list: D005819:Genetic Markers