A method for the obtaining of increased viscosity eye drops containing amikacin.
A method for the obtaining of increased viscosity (3.6-52.5 cP) eye drops, containing amikacin-aminoglycoside antibiotic and as increasing viscosity agents: polivinyl alkohol, hydroxyethylcellulose or sodium hyaluronate was elaborated. Physicochemical and biological properties of these eye drops were determined.
Sikora
Adam
A
Institute of Biotechnology and Antibiotics, 5 Starościńska Str., 02-516 Warsaw.
Oszczapowicz
Irena
I
Tejchman
Bozena
B
Grzechnik
Małgorzata
M
D000583:Amikacin / Q000008:administration & dosage* / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000737:chemistry; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004339:Drug Compounding; D004355:Drug Stability; D007202:Indicators and Reagents; D009883:Ophthalmic Solutions; D011310:Preservatives, Pharmaceutical; D014783:Viscosity
D000900:Anti-Bacterial Agents; D007202:Indicators and Reagents; D009883:Ophthalmic Solutions; D011310:Preservatives, Pharmaceutical; D000583:Amikacin