title: High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments.
abstract: HRMAS NMR of tau paired helical fragments assembled with heparin show an intensity decrease for those amino acids that are incorporated into the rigid core region, whereas the N-terminal amino acids maintain their full mobility.
authors: CNRS - Université de Lille 2 UMR 8525 and Inserm IFR17, Institut Pasteur de Lille, BP 245 - F-59019 Lille Cedex, France.
authors: Alain
authors: A
authors: Sillen
authors: Jean-Michel
authors: JM
authors: Wieruszeski
authors: Arnaud
authors: A
authors: Leroy
authors: Amena Ben
authors: AB
authors: Younes
authors: Isabelle
authors: I
authors: Landrieu
authors: Guy
authors: G
authors: Lippens
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism; D007382:Intermediate Filaments / Q000737:chemistry* / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D016875:tau Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D016875:tau Proteins