Asymmetric synthesis of cyclopropanes from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes.
A diastereo- and enantiospecific formation of tetrasubstituted cyclopropane carbene complexes and cyclopropanecarboxylates from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes is described.
Capriati
Vito
V
Dipartimento Farmaco-Chimico, Università di Bari, Via E. Orabona 4, I-70126 Bari, Italy.
Florio
Saverio
S
Luisi
Renzo
R
Perna
Filippo Maria
FM
Barluenga
José
J
D002264:Carboxylic Acids / Q000737:chemistry*; D003521:Cyclopropanes / Q000138:chemical synthesis*; D005027:Ethylene Oxide / Q000737:chemistry*; D006838:Hydrocarbons; D006844:Hydrocarbons, Cyclic / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D002264:Carboxylic Acids; D003521:Cyclopropanes; D006838:Hydrocarbons; D006844:Hydrocarbons, Cyclic; C030011:carbene; D008094:Lithium; D005027:Ethylene Oxide; D008697:Methane