title: Sexual dysfunction in female subjects with fibromyalgia.
abstract: OBJECTIVE
  We investigated sexual function in females with fibromyalgia (FM) and evaluate whether coexistent major depression (MD) has an additional negative effect on sexual function.
  
  
  METHODS
  A total of 100 female subjects were enrolled in the study, including 40 with FM only, 27 with FM plus MD and 33 healthy volunteers as a control group. The diagnosis of MD was made according to Structured Clinical Interview for Diagnostic and Statistical Manual-IV interview and the Hamilton Depression Rate Scale was used to grade depression. Widespread pain and quality of life were assessed with the Lattinen Pain Scale and Fibromyalgia Impact Questionnaire, respectively. The Female Sexual Function Index (FSFI) was used to assess sexual dysfunction.
  
  
  RESULTS
  All subjects were comparable in age, occupation and education. Mean FSFI total score +/- SD was significantly decreased in the FM and FM plus MD groups compared with that in healthy controls (21.83 +/- 5.84 and 22.43 +/- 7.0 vs 28.10 +/- 6.52, respectively, p = 0.001). However, the FSFI score was not significantly different between patients with FM only and FM plus MD (p >0.05). Correlation analysis revealed a negative moderate correlation between total Lattinen pain score and FSFI score in the FM only and FM plus MD groups (r = -0.366, p = 0.047 and r = -0.403, p = 0.018, respectively). FSFI score did not correlate with FIQ and HDRS scores (p >0.05).
  
  
  CONCLUSIONS
  This study demonstrates that female patients with FM have distinct sexual dysfunction compared with healthy controls and coexistent MD has no additional negative effect on sexual function. Thus, female subjects with FM should be evaluated in terms of sexual function to provide better quality of life.
authors: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Celal Bayar University, Manisa, Turkey. canan.tikiz@bayar.edu.tr
authors: Canan
authors: C
authors: Tikiz
authors: Talha
authors: T
authors: Muezzinoglu
authors: Timur
authors: T
authors: Pirildar
authors: E Oryal
authors: EO
authors: Taskn
authors: Altinay
authors: A
authors: Frat
authors: Cigdem
authors: C
authors: Tuzun
mesh_terms: D000328:Adult; D001143:Arousal; D015897:Comorbidity; D003866:Depressive Disorder / Q000453:epidemiology; D005260:Female; D005356:Fibromyalgia / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009948:Orgasm; D011788:Quality of Life; D012720:Severity of Illness Index; D020018:Sexual Dysfunctions, Psychological / Q000453:epidemiology*; D011795:Surveys and Questionnaires