Imaging and other biomarkers in early clinical studies: one step at a time or re-engineering drug development?
Collins
Jerry M
JM
D000284:Administration, Oral; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000077784:Axitinib; D014408:Biomarkers, Tumor / Q000032:analysis*; D002986:Clinical Trials as Topic; D003952:Diagnostic Imaging; D015195:Drug Design; D015507:Drugs, Investigational / Q000627:therapeutic use*; D006801:Humans; D007093:Imidazoles; D007191:Indazoles / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*; D009389:Neovascularization, Pathologic / Q000188:drug therapy*
D020533:Angiogenesis Inhibitors; D014408:Biomarkers, Tumor; D015507:Drugs, Investigational; D007093:Imidazoles; D007191:Indazoles; D000077784:Axitinib