title: Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites.
authors: Department of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06511, USA.
authors: Matthew P
authors: MP
authors: Glenn
authors: Sung-Youn
authors: SY
authors: Chang
authors: Oliver
authors: O
authors: Hucke
authors: Christophe L M J
authors: CL
authors: Verlinde
authors: Kasey
authors: K
authors: Rivas
authors: Carrie
authors: C
authors: Hornéy
authors: Kohei
authors: K
authors: Yokoyama
authors: Frederick S
authors: FS
authors: Buckner
authors: Prakash R
authors: PR
authors: Pendyala
authors: Debopam
authors: D
authors: Chakrabarti
authors: Michael
authors: M
authors: Gelb
authors: Wesley C
authors: WC
authors: Van Voorhis
authors: Saïd M
authors: SM
authors: Sebti
authors: Andrew D
authors: AD
authors: Hamilton
mesh_terms: D000284:Administration, Oral; D000813:Anilides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D000962:Antimalarials / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D001665:Binding Sites; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D051231:Farnesyltranstransferase / Q000037:antagonists & inhibitors*; D008099:Liver / Q000187:drug effects; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism; D008958:Models, Molecular; D015394:Molecular Structure; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000254:growth & development*; D051381:Rats; D013329:Structure-Activity Relationship; D013997:Time Factors
chemical_list: D000813:Anilides; D000962:Antimalarials; D004791:Enzyme Inhibitors; D051231:Farnesyltranstransferase