2-Pyrone natural products and mimetics: isolation, characterisation and biological activity.
The review summarises natural products containing the 2-pyrone moiety. An emphasis has been placed upon the biological activity associated with 2-pyrones, particularly with respect to potential therapeutic or anti-microbial agents. Where appropriate, non-natural 2-pyrone analogues are discussed, particularly those derived from natural product lead compounds.
McGlacken
Gerard P
GP
Department of Chemistry, University of York, Heslington, York, UK YO10 5DD.
Fairlamb
Ian J S
IJ
D000544:Alzheimer Disease / Q000188:drug therapy; D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000924:Anticholesteremic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018716:Molecular Mimicry; D015394:Molecular Structure; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D019380:Anti-HIV Agents; D000924:Anticholesteremic Agents; D000970:Antineoplastic Agents; D001688:Biological Products; D011753:Pyrones