title: Synthesis of 5/7-, 5/8- and 5/9-bicyclic lactam templates as constraints for external beta-turns.
abstract: The 5/7-, 5/8- and 5/9-bicyclic lactams 3, 17, 5 and 6 have been synthesised as single diastereoisomers by a route involving ring closing olefin metathesis. The X-ray crystal structure of the amino acid hydrochloride has been carried out and compared to that of the saturated external beta-turn constraint 18.
authors: Department of Chemistry, University of Sussex, Falmer, Brighton, UK BN1 9QJ.
authors: Heather M E
authors: HM
authors: Duggan
authors: Peter B
authors: PB
authors: Hitchcock
authors: Douglas W
authors: DW
authors: Young