title: Perinatal outcomes of polyhydramnios without associated congenital fetal anomalies after the gestational age of 20 weeks.
abstract: BACKGROUND
  Polyhydramnios carries a high rate of complications during pregnancy and adverse perinatal outcomes. We could find no studies of this condition in a large Asian population. The aim of this investigation was to evaluate the risks of adverse perinatal outcomes in a large study population with polyhydramnios without associated fetal anomalies after the gestational age of 20 weeks in Taiwan.
  
  
  METHODS
  We retrospectively reviewed the computerized records of women who had babies without associated fetal anomalies after the gestational age of 20 weeks at Chang Gung Memorial Hospital from July 1990 to December 2001. Possible confounding factors that could affect the occurrence of polyhydramnios were analyzed. We then investigated the relative risks of these events to adverse perinatal outcome by adjusting the variants.
  
  
  RESULTS
  Significantly higher incidences of preeclampsia, placental abruption, placenta accreta, past history of fetal death or preterm delivery, multiple pregnancy, bodyweight gain > or = 20kg during pregnancy and primiparity were noted in patients with polyhydramnios than in patients without this condition. The presence of polyhydramnios significantly increased the rate of preterm delivery, low birth weight or very low birth weight, low one- and five-minute Apgar scores, fetal death, large for gestational age babies, meconium-stained amniotic fluid, Cesarean section, fetal distress in labor, NICU transfer and neonatal death.
  
  
  CONCLUSIONS
  Polyhydramnios carried a higher incidence of adverse perinatal outcomes, such as low Apgar scores, fetal death, fetal distress in labor, NICU transfer and neonatal death, despite exclusion of congenital anomalies from the study population. Detailed antepartum fetal well-being surveillance, intensive intrapartum monitoring and further attention postpartum are warranted in patients with this condition.
authors: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital. 199, Duenhua N. Road, Sungshan Chiu, Taipei, Taiwan 105, ROC. kib56684@yahoo.com
authors: Kuang-Chao
authors: KC
authors: Chen
authors: Jui-Der
authors: JD
authors: Liou
authors: Tai-Ho
authors: TH
authors: Hung
authors: Dong-Ming
authors: DM
authors: Kuo
authors: Jenn-Jeih
authors: JJ
authors: Hsu
authors: Ching-Chang
authors: CC
authors: Hsieh
authors: Tsang-Tang
authors: TT
authors: Hsieh
mesh_terms: D001034:Apgar Score; D001724:Birth Weight; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D007752:Obstetric Labor, Premature / Q000209:etiology; D006831:Polyhydramnios / Q000150:complications*; D011247:Pregnancy; D012189:Retrospective Studies