title: Distinguishing acute-onset CIDP from Guillain-Barré syndrome with treatment related fluctuations.
abstract: Guillain-Barré syndrome (GBS) patients may worsen after initial treatment (treatment-related fluctuation [TRF]). It is difficult to distinguish GBS-TRF from chronic inflammatory demyelinating polyneuropathy with acute onset (A-CIDP). The authors compared 13 patients with A-CIDP with 11 patients with GBS-TRF and concluded that A-CIDP should be suspected when a patient with GBS deteriorates after 9 weeks from onset or when deterioration occurs three times or more. Maintenance treatment should then be considered.
authors: Department of Neurology, Erasmus MC, Rotterdam, The Netherlands. l.ruts@erasmusmc.nl
authors: Liselotte
authors: L
authors: Ruts
authors: Rinske
authors: R
authors: van Koningsveld
authors: Pieter A
authors: PA
authors: van Doorn
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D009460:Neurologic Examination; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000503:physiopathology; D011237:Predictive Value of Tests; D011379:Prognosis; D012008:Recurrence; D013997:Time Factors