title: [Quality assessment of Coptis chinensis in China].
abstract: OBJECTIVE
  To study the dynamic change of the ingredients of Coptis chinensis and evaluate the quality of the crude drugs from main producing areas.
  
  
  METHODS
  The ingredients of samples from Shizhu and Wuxi counties in Chongqing, Hongya and Dayi counties in Sichuan, Zhenping county in Shanxi, Lichuan county in Hubei were analyzed for berberine, coptisine, jatrorrhizine, palmatine and the total alkaloids by HPLC and UV methods.
  
  
  CONCLUSIONS
  The contents of measured indexes were mostly highest in 5-years-old C. chinensis. Considering factors such as the yield, it is reasonable to harvest the 5-years-old C. chinensis. There are minor differences in condents of C. chinensis from different areas, all tested samples met the pharmacopoeial standards. It is concluded that the general quality of C. chinensis was good and acceptable.
authors: Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China. zgy@cqacmm.com
authors: Guo-yue
authors: GY
authors: Zhong
authors: Xiao-ping
authors: XP
authors: Huang
authors: Kai-sen
authors: KS
authors: Ma
authors: Shi-jiang
authors: SJ
authors: Chen
authors: Song-yun
authors: SY
authors: Qin
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D001599:Berberine / Q000031:analogs & derivatives / Q000032:analysis; D001600:Berberine Alkaloids / Q000032:analysis; D002681:China; D002851:Chromatography, High Pressure Liquid; D039323:Coptis / Q000737:chemistry* / Q000145:classification; D017753:Ecosystem; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000470:Alkaloids; D001600:Berberine Alkaloids; C055785:jatrorrhizine; C034384:coptisine; D001599:Berberine; C005413:palmatine