[COX-2 expression and ovarian cancer].
The aim of the present review is to study the significance of the COX-2 expression for unfavourable prognosis and aggressive clinicopathological parameters in certain malignancies. The main directions for future research on COX-2 as a prognostic factor of decreased survival and predictive factor of chemotherapy resistance in ovarian cancer are discussed.
Uzunova
E
E
Kornovski
Ia
Ia
Tsvetkov
Ts
Ts
Ianeva
R
R
D051546:Cyclooxygenase 2; D005260:Female; D006801:Humans; D008565:Membrane Proteins; D010051:Ovarian Neoplasms / Q000201:enzymology* / Q000473:pathology; D011379:Prognosis; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis*
D008565:Membrane Proteins; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases