[Assisting protective effect of Yiyuan oral solution on mice from irradiation injury].
OBJECTIVE
To study the protective effect of Yiyuan oral solution against radiation injury in mice.


METHODS
Yiyuan oral solution was administered in mice at 10.00, 3.33 and 1.67 ml/kg for 30 days. The mice were then exposed to (60)Co-gamma irradiation at 3 Gy once and the effect of the irradiation on the WBC, bone marrow polychromatic erythrocytes (PEC) micronuclei and serum hemolysin antibody against sheep red cells.


CONCLUSIONS
Yiyuan oral solution at 10 ml/kg significantly increased WBC counts, decreased bone marrow PEC micronucleus rate and enhanced serum hemolysin antibody in mice, suggesting the protective effect of this preparation against radiation injury.
Luo
Su-fang
SF
Institute of Health Food, Southern Medical University, Guangzhou 510515, China.
Liu
Guo-zhang
GZ
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008517:Phytotherapy; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*
D004365:Drugs, Chinese Herbal; D011837:Radiation-Protective Agents