Facile construction of the benzofuran and chromene ring systems via PdII-catalyzed oxidative cyclization.
[reaction: see text]. We herein report the development of one-pot procedures for the conversion of allyl aryl ethers to 2-methylbenzofurans (via sequential Claisen rearrangement and oxidative cyclization) and for the conversion of aryl homoallyl ethers to chromenes (via direct oxidative cyclization). It is likely that both reactions proceed via a common Pd-catalyzed pathway involving olefin activation, nucleophilic attack, and beta-hydride elimination.
Youn
So Won
SW
Department of Chemistry, Pukyong National University, Busan, Korea. sowony@pknu.ac.kr
Eom
Jeong Im
JI