title: "Bicellar" lipid mixtures as used in biochemical and biophysical studies.
abstract: Over the past decade "bicellar" lipid mixtures composed of the long-chain dimyristoyl phosphatidylcholine (DMPC) and the short-chain dihexanoyl PC (DHPC) molecules have emerged as a powerful medium for studying membrane associated, biologically relevant macromolecules and assemblies. Depending on temperature, lipid concentration and composition these lipid mixtures can assume a variety of morphologies, some of them alignable in the presence of a magnetic field. This article will examine the biophysical studies that have elucidated the various morphologies assumed by these lipid mixtures, and their use in the biochemical studies of biomolecules.
authors: National Research Council, Chalk River Laboratories, Chalk River, Ontario, Canada. john.katsaras@nrc-cnrc.gc.ca
authors: John
authors: J
authors: Katsaras
authors: Thad A
authors: TA
authors: Harroun
authors: Jeremy
authors: J
authors: Pencer
authors: Mu-Ping
authors: MP
authors: Nieh
mesh_terms: D001669:Biochemical Phenomena; D001671:Biochemistry; D055592:Biophysical Phenomena; D001703:Biophysics; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D008567:Membranes, Artificial; D008958:Models, Molecular; D010742:Phospholipid Ethers / Q000737:chemistry
chemical_list: C052298:1,2-dihexadecyl-sn-glycero-3-phosphocholine; D008081:Liposomes; D008567:Membranes, Artificial; D010742:Phospholipid Ethers; D004134:Dimyristoylphosphatidylcholine