title: Effect of imidazobenzoimidazole derivatives RU-353, RU-563, and lidocaine on cerebral circulation in rats.
abstract: We demonstrated a dose-dependent inhibitory effect of novel imidazobenzoimidazole derivatives RU-353 and RU-563 on cerebral blood flow and systemic blood pressure in narcotized rats. The effects of RU-353 increased, while the effect of RU-563 decreased with increasing the dose.
authors: Kuban State Medical Academy, Krasnodar; Krasnodar Regional Research Medical Center, Russia.
authors: A P
authors: AP
authors: Galenko-Yaroshevskii
authors: A Yu
authors: AY
authors: Turovaya
authors: A V
authors: AV
authors: Uvarov
authors: A K
authors: AK
authors: Prikhod'ko
authors: M N
authors: MN
authors: Ivashev
authors: A V
authors: AV
authors: Arl't
authors: V A
authors: VA
authors: Anisimova
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008012:Lidocaine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001562:Benzimidazoles; C507880:RU 353; C507881:RU 563; D008012:Lidocaine