title: Molecular virology of the hepatitis C virus: implication for novel therapies.
abstract: The study of hepatitis C virus (HCV) molecular virology is helping to shape the future of our anti-HCV strategies by identifying new antiviral targets. With the advent of agents that specifically target individual HCV proteins, HCV-specific therapy has arrived. Key to these efforts is the development of high-efficiency HCV replicons. The future effective pharmacologic control of HCV will likely consist of a cocktail of simultaneously administered virus-specific agents with independent targets. This should minimize the emergence of resistance against any single agent. The way we treat HCV should change dramatically over the next few years.
authors: Division of Gastroenterology and Hepatology, Stanford University School of Medicine and Palo Alto Veterans Administration Medical Center, CCSR Building, Room 3115, 269 Campus Drive, Palo Alto, CA 94305-5187, USA. jeffrey.glenn@stanford.edu
authors: Jeffrey S
authors: JS
authors: Glenn
mesh_terms: D016174:Hepacivirus / Q000235:genetics* / Q000254:growth & development; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D012093:Replicon / Q000502:physiology; D014764:Viral Proteins / Q000502:physiology
chemical_list: D014764:Viral Proteins