[Evaluation of the influence of the bacterial vaccines Pneumo-23 and Act-HIB on the course of the chronic inflammatory process of the respiratory organs in children].
The effectiveness and safety of vaccination of children having chronic inflammatory lung diseses with Pneumo-23 and Act-HIB were evaluated. The group under study included 38 children having chronic pneumonia, congenital defects of lung development, Kartagener's syndrome, mucoviscidosis; of these children, 25 were vaccinated with Pneumo-23 and 13--with Act-HIB. For comparison a group of 40 children with the same pathology, but not vaccinated, was used. A favorable course of the postvaccinal period was noted. Prior to vaccination Streptococcus pneumoniae in association with Haemophilus influenzae were isolated from all patients; in a year after vaccination with Pneumo-23 these microorganisms were isolated only in monoculture: S. pneumoniae in 3 out of 25 cases (88% elimination) and H. influenzae in 10 out of 25 cases (60% elimination).
Ryzhov
A A
AA
Katosova
L K
LK
Kostinov
M P
MP
Volkov
I K
IK
Magarshak
O O
OO
D000293:Adolescent; D016667:Bacterial Capsules; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006192:Haemophilus Infections / Q000382:microbiology / Q000517:prevention & control*; D018073:Haemophilus Vaccines / Q000008:administration & dosage*; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D011008:Pneumococcal Infections / Q000382:microbiology / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D018410:Pneumonia, Bacterial / Q000382:microbiology / Q000517:prevention & control*; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage*; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000517:prevention & control*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D022282:Vaccines, Acellular / Q000008:administration & dosage; D018074:Vaccines, Conjugate / Q000008:administration & dosage
C414006:23-valent pneumococcal capsular polysaccharide vaccine; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D022242:Pneumococcal Vaccines; D011135:Polysaccharides, Bacterial; D022282:Vaccines, Acellular; D018074:Vaccines, Conjugate