title: Acral pseudolymphomatous angiokeratoma of children (APACHE).
abstract: 13-year-old girl presented with a 10-year history of multiple discrete red firm papules situated on her right upper arm. The histopathology examination revealed a massive subepidermal lymphohistiocytic infiltrate, consistent with acral pseudolymphomatous angiokeratoma of children. Treatment with topical application of mometasone furoate 0.1% cream once daily for 6 months improved the lesions partially. However, these papules returned to their pretreatment appearance and consistency within 6 months after the cessation of the topical corticosteroid. The authors prefer the term 'papular angiolymphoid hyperplasia' for this entity, based on the absence of histological angiokeratomatous features, the benign nature of the lesion and the previously reported cases from adults and non-acral sites.
authors: Department of Dermatology, Concord Hospital, University of Sydney, Sydney, New South Wales, Australia. kimabel@hanmail.net
authors: Youngjin
authors: Y
authors: Kim
authors: Elizabeth
authors: E
authors: Dawes-Higgs
authors: Stephen
authors: S
authors: Mann
authors: David K
authors: DK
authors: Cook
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000794:Angiokeratoma / Q000175:diagnosis* / Q000188:drug therapy; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001132:Arm; D005260:Female; D006801:Humans; D000068656:Mometasone Furoate; D011244:Pregnadienediols / Q000008:administration & dosage; D019310:Pseudolymphoma / Q000175:diagnosis* / Q000188:drug therapy; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011244:Pregnadienediols; D000068656:Mometasone Furoate