Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor.
A new system for the colorimetric detection of oligonucleotides was developed using polydiacetylene vesicles, which play the dual role of an indicator of color transition and an amplification tag. The results are of significance in understanding the mechanism of color transition of biological recognition in polydiacetylene systems and in designing new biosensors.
Wang
Chungang
C
Chemistry Department, Northeast Normal University, Changchun 130024, P. R. China.
Ma
Zhanfang
Z
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D003124:Colorimetry; D003432:Cross-Linking Reagents / Q000737:chemistry*; D018076:DNA, Complementary / Q000032:analysis; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry; D005231:Fatty Acids, Unsaturated / Q000737:chemistry; D009841:Oligonucleotides / Q000032:analysis*; D000078789:Polyacetylene Polymer; D011108:Polymers / Q000737:chemistry*; D053279:Polyynes / Q000737:chemistry*
C434762:10,12-tricosadiynoic acid; D003432:Cross-Linking Reagents; D018076:DNA, Complementary; D005231:Fatty Acids, Unsaturated; D009841:Oligonucleotides; D000078789:Polyacetylene Polymer; D011108:Polymers; D053279:Polyynes; C082361:polydiacetylene; D004134:Dimyristoylphosphatidylcholine