Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses.
We demonstrate that frequency-swept pulses can be used for the selective and enhanced detection of quadrupolar nuclei located in anisotropic environments. The primary driving force for this technique development is the field of sodium-MRI, where sodium signals from locally ordered environments are known to be diagnostic of cartilage defects. We demonstrate here simple one-dimensional images of model systems, in which the signals from free sodium ions are suppressed, while ordered sodium is detected via the narrow central transition signal.
Ling
Wen
W
Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, USA.
Jerschow
Alexej
A
D000465:Algorithms; D003287:Contrast Media; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D019047:Phantoms, Imaging; D011846:Radio Waves; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D012964:Sodium / Q000032:analysis* / Q000737:chemistry; D013113:Spin Labels
D003287:Contrast Media; D013113:Spin Labels; D012964:Sodium