Adherence to antidepressant medications in black and Latino elderly patients.
OBJECTIVE
The purpose of this pilot study was to identify ethnic group differences in nonadherence and to determine predictors of nonadherence to antidepressant medications in older minority-group members.


METHODS
Participants were 49 black and 52 Latino subjects over the age of 55 who had been prescribed antidepressant medications within the past 12 months.


RESULTS
We found a distinction between intentional nonadherence (e.g., alteration of medication regimen to fit one's needs) and unintentional nonadherence (e.g., forgetfulness/difficulties keeping track of medication regimen). Results suggested that older Latino subjects reported significantly more unintentional nonadherence than older black subjects. However, once other predictors were entered into the model, ethnicity did not remain a significant predictor. No ethnic group differences in intentional nonadherence were suggested. After controlling for ethnicity and medication type, intentional nonadherence was associated with concerns about the side effects of antidepressant medications, the stigma associated with antidepressant medications, and the attribution of lesser importance to antidepressant medications than other medications. Unintentional nonadherence was associated with greater cognitive impairment.


CONCLUSIONS
Results suggest that the two ethnic minority groups face similar barriers to adherence to antidepressant medications. Interventions to increase adherence should target the specific type of nonadherence presented by the elderly patients. Some may benefit from memory aids and the assistance of family and friends, others from specific educational interventions about the nature of depression and antidepressant medications.
Ayalon
Liat
L
Univ. of California, San Francisco, 401 Parnassus Ave., CPT, San Francisco, CA 94143, USA. liata@lppi.ucsf.edu
Areán
Patricia A
PA
Alvidrez
Jennifer
J
D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D044383:Black People / Q000523:psychology / Q000706:statistics & numerical data*; D003710:Demography; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000208:ethnology* / Q000523:psychology; D005260:Female; D006630:Hispanic or Latino / Q000523:psychology / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D010817:Physician-Patient Relations
D000928:Antidepressive Agents