Bone metastasis of Wilms' tumor with monophasic epithelial histology in a young adult.
A unique case of Wilms' tumor with monophasic epithelial histology in the bone metastasis at initial presentation in an 18-year-old Taiwanese girl is presented. Histologically, a purely differentiated epithelial component in the L1-3 vertebrae was noted, which is consistent with the epithelial component in primary Wilms' tumor of the kidney by both microscopy and immunohistochemistry. Hence, Wilms' tumor should be included in the differential diagnosis of a metastatic lesion presenting a purely epithelial histology in a young adult or a child.
Lu
Sheng-Yun
SY
Department of Pathology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan.
Eng
Hock-Liew
HL
Chen
Wei-Jen
WJ
Chen
Tai-Yi
TY
Wang
Hua-Pin
HP
Huang
Chao-Cheng
CC
D000293:Adolescent; D001859:Bone Neoplasms / Q000473:pathology* / Q000556:secondary*; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D009396:Wilms Tumor / Q000473:pathology*