Fixed drug eruption with interferon-beta-1b.
A 32-year-old woman with multiple sclerosis who developed non-injection-site-related fixed drug eruption with interferon-beta-1b. Erythematous plaques started appearing 1 month after the drug was introduced, and increased in number following each administration. The histopathology of a skin biopsy was consistent with fixed drug eruption. The drug was subsequently ceased, with resolution of the rash 6 weeks later.
Tai
Yee J
YJ
Department of Dermatology, St. Vincent's Hospital, Melbourne, Victoria, Australia. yeejentai@yahoo.com
Tam
Mei
M
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D016899:Interferon-beta / Q000008:administration & dosage / Q000009:adverse effects*; D009103:Multiple Sclerosis / Q000188:drug therapy
D000276:Adjuvants, Immunologic; D016899:Interferon-beta