title: Changing trends in antimicrobial-resistant pneumococci: it's not all bad news.
abstract: In the early 1990s, we witnessed a dramatic and relentless increase in multidrug-resistant pneumococci worldwide. However, there is now evidence of decreasing resistance to some antimicrobials in some regions of the world. This may well be a result of several initiatives to promote the judicious use of antimicrobials, as well as the introduction of the pneumococcal conjugate vaccine, suggesting that the fight against resistance is maybe not futile.
authors: Department of Microbiology, University Health Network/Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada. dlow@mtsinai.on.ca
authors: Donald E
authors: DE
authors: Low
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D014943:Global Health; D006801:Humans; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000188:drug therapy* / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D022242:Pneumococcal Vaccines; D015995:Prevalence; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents; D022242:Pneumococcal Vaccines