title: Environmental reduplicative paramnesia in a case of atypical Alzheimer's disease.
abstract: A 79-year-old patient with neuropathologically confirmed Alzheimer's disease (AD) presented with a selective environmental reduplicative paramnesia (RP), the belief that one or more environments exist simultaneously in two or more physical locations. Clinical presentation and neuropathological examination revealed an atypical form of AD. High neurofibrillary tangle densities were observed in the frontal and temporal association cortex, whereas the parietal and entorhinal cortex, as well as the hippocampus, were nearly spared. These findings are compared to those reported in frontal and frontotemporal variants of AD and discussed in the light of current anatomoclinical models for environmental RP.
authors: Service Universitaire de Psychiatrie de l' Age Avancé, Centre Hospitalier Universitaire Vandois, Lausanne, Switzerland. armin.von-gunten@inst.hospvd.ch
authors: Armin
authors: A
authors: von Gunten
authors: Judit
authors: J
authors: Miklossy
authors: Mario-Luca
authors: ML
authors: Suvà
authors: Patrick R
authors: PR
authors: Hof
authors: Panteleimon
authors: P
authors: Glannakopoulos
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D000647:Amnesia / Q000209:etiology*; D001288:Attention / Q000502:physiology; D002540:Cerebral Cortex / Q000473:pathology; D003071:Cognition / Q000502:physiology; D004644:Emotions; D004777:Environment; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D007360:Intelligence / Q000502:physiology; D007802:Language; D008297:Male; D016874:Neurofibrillary Tangles / Q000473:pathology; D009949:Orientation / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D012563:Schizophrenia, Paranoid / Q000209:etiology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D014796:Visual Perception / Q000502:physiology