title: Bitter and sweet/umami taste receptors with differently evolutionary pathways.
abstract: In this study,we investigated the evolutionary pathways of bitter, sweet and umami receptors using bioinformatic and phylogenetic analyses. Our results showed that the distantly evolutionary relationship between bitter and sweet/umami receptors. Our results also showed that bitter and sweet/umami receptors have differently evolutionary pathways,suggesting that the different evolutionary pathways may resulte in the differences of these three receptors in function.
authors: Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
authors: Peng
authors: P
authors: Shi
authors: Jing-Fei
authors: JF
authors: Huang
authors: Ya-Ping
authors: YP
authors: Zhang
mesh_terms: D000595:Amino Acid Sequence; D002630:Chemotactic Factors / Q000235:genetics*; D019143:Evolution, Molecular; D006801:Humans; D008957:Models, Genetic; D008969:Molecular Sequence Data; D010802:Phylogeny; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D013649:Taste; D000098706:Taste Receptors, Type 2
chemical_list: D002630:Chemotactic Factors; D043562:Receptors, G-Protein-Coupled; C414724:VN1R1 protein, human; C431926:taste receptors, type 1; D000098706:Taste Receptors, Type 2