title: Indium triflate-catalyzed vinylation of beta-ketoesters with acetylene gas.
abstract: [reaction: see text]. An In(OTf)(3)-catalyzed addition of a beta-ketoester to acetylene in the presence of molecular sieves produces a alpha-vinylated ketoester in good to excellent yield. The vinylation reaction proceeds without any loss of elements in starting molecules under solvent-free conditions and allows the use of welding-grade acetylene, providing a practical method for synthetic utilization of acetylene gas.
authors: Department of Chemistry, The University of Tokyo, Hongo, Bunkyo-ku, Japan.
authors: Masaharu
authors: M
authors: Nakamura
authors: Kohei
authors: K
authors: Endo
authors: Eiichi
authors: E
authors: Nakamura