Incidence of pneumococcal endocarditis: a regional health register-based study in Denmark 1981-1996.
The aim of this study was to determine the incidence of pneumococcal endocarditis in 3 Danish counties. By linking the National Hospital Discharge Registry to regional blood culture registries maintained by the Department of Clinical Microbiology and autopsy registries from the Department of Pathology, a total of 31 cases of pneumococcal endocarditis was identified in the 3 counties during a period of 16 y (1981-1996). One patient experienced 2 independent episodes as determined by serotyping. The annual incidence increased approximately 4-fold during the study period, giving an overall incidence rate of 0.15 per 100,000 inhabitants. Pneumococcal endocarditis was diagnosed in 1.2% of cases of pneumococcal bacteraemia. Some cases may have remained undetected, and this underlines the need for clinical attention to this diagnosis. The study confirms that linkage of health registries is a valid method of conducting surveys of uncommon diseases.
Lindberg
Jens
J
Department of Internal Medicine, Herning Hospital, Herning, Denmark.
Schønheyder
Henrik C
HC
Møller
Jens K
JK
Prag
Jørgen
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000453:epidemiology*; D003718:Denmark / Q000453:epidemiology; D004697:Endocarditis, Bacterial / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000453:epidemiology*; D012042:Registries