Anaesthesia induced neuroprotection.
Anaesthetic agents display remarkable neuroprotective potential; here, we describe the evidence supporting its use and highlight areas for future development of the field. In particular the application of isoflurane and/or xenon as inhalational neuroprotectants is advocated and evidence for the neuroprotection provided by barbiturates and suppression of cerebral metabolic rate is discussed.
Sanders
Robert D
RD
Department of Anaesthetics and Intensive Care Medicine, Imperial College London, Chelsea and Westminster Hospital, 369 Fulham Rd, London SW10 9NH, UK. robert.sanders@ic.ac.uk
Ma
Daqing
D
Maze
Mervyn
M
D000758:Anesthesia; D018685:Anesthetics, Inhalation / Q000494:pharmacology; D000818:Animals; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology; D009422:Nervous System Diseases / Q000139:chemically induced / Q000517:prevention & control*; D019636:Neurodegenerative Diseases / Q000139:chemically induced / Q000517:prevention & control; D018696:Neuroprotective Agents
D018685:Anesthetics, Inhalation; D018696:Neuroprotective Agents; D007530:Isoflurane