title: Subcutaneous ivermectin as a safe salvage therapy in Strongyloides stercoralis hyperinfection syndrome: a case report.
abstract: Strongyloides stercoralis hyperinfection syndrome due to the acceleration of the autoinfective cycle of the nematode is a life-threatening form of the infection occurring in immunocompromised hosts. Intestinal ileus, which is commonly encountered in this form, may reduce the bioavailability and thus the efficacy of oral anthelminthic drugs used in the treatment of the S. stercoralis hyperinfection syndrome. We report the efficacy and safety of subcutaneous administration of ivermectin in a patient infected with human T cell lymphotropic virus type I with S. stercoralis hyperinfection syndrome who was unresponsive to an oral combination of ivermectin and albendazole.
authors: Départements de Microbiologie, Soins Intensifs de Pneumologie, et d'Oncologie Médicale, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, Pairs, France.
authors: Jerome
authors: J
authors: Pacanowski
authors: Marie Dos
authors: MD
authors: Santos
authors: Antoine
authors: A
authors: Roux
authors: Christine
authors: C
authors: LE Maignan
authors: Jacques
authors: J
authors: Guillot
authors: Veronique
authors: V
authors: Lavarde
authors: Muriel
authors: M
authors: Cornet
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D007560:Cote d'Ivoire / Q000208:ethnology; D017809:Fatal Outcome; D005602:France; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use*; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications*; D008297:Male; D017171:Strongyloides stercoralis; D013322:Strongyloidiasis / Q000150:complications / Q000188:drug therapy*
chemical_list: D000871:Anthelmintics; D007559:Ivermectin