title: Pfropfschizophrenia in the age of deinstitutionalization: whose problem?
abstract: BACKGROUND
  The Kraepelinian concept of pfropfschizophrenia refers to the intertwined coexistence of mental retardation and schizophrenia. Patients with this syndrome are relatively treatment resistant and are often harmed by diverging policies and cost cuts within the framework of mental health care services. Thus, a better understanding of this syndrome has important practical implications. The multiple problems that these patients encounter in various educational and health care agencies and what questions need to be asked to better elucidate these patients' needs are assessed.
  
  
  METHODS
  Three case reports of adult long-term inpatients fulfilling the criteria for pfropfschizophrenia are presented. Their current mental status and illness histories are discussed in relation to hypothesized pathophysiological processes and current needs.
  
  
  CONCLUSIONS
  Small cohort, naturalistic study.
  
  
  CONCLUSIONS
  Pfropfschizophrenia is a phenotypically heterogeneous syndrome. The chronology of the appearance of cognitive deficits and psychotic symptoms during the course of this disorder should be carefully assessed because it may reflect diverse pathophysiological processes, necessitating differentiated, specific treatment interventions.
authors: Research Department, Ezrath Nashim-Herzog Memorial Hospital, Jerusalem, Israel. saradoc@mailworks.org
authors: Sara
authors: S
authors: Catinari
authors: Agnes
authors: A
authors: Vass
authors: Marina
authors: M
authors: Ermilov
authors: Uriel
authors: U
authors: Heresco-Levy
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003072:Cognition Disorders / Q000209:etiology; D003688:Deinstitutionalization; D005260:Female; D006304:Health Status; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D011582:Psychological Theory; D011618:Psychotic Disorders / Q000209:etiology; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology* / Q000628:therapy*
chemical_list: D014150:Antipsychotic Agents