[Sentinel lymph dissection in cervical cancer--prognostic factors].
BACKGROUND
The concept for the sentinel lymph nodes is one of the most significant and interesting achievements in clinical oncology in the last 10 years. It is possible according to it, by dissection and studing of one or a small number of lymph nodes, the status of the regional lymphatic network drainage to be foreseen.


OBJECTIVE
To study the application of sentinel lymph nodes detection by applying Patent blue V marker in patients with invasive cervical cancer who had undergone radical hysterectomy and pelvic and/or paraaortic lymph detection.


METHODS
In a prospective study in the period from January 2001- December 2003 the mapping technique for detection of the sentinel lymph nodes was utilized in 129 patients with cervical cancer. Preoperativly 2 ml. Patent blue V was injected into the cervix. Intraoperativly it was looked for blue coloured lymph flows going to the first (sentinel) lymph nodes in the pelvic lymphatic network drainage and the paraaortic area. All patients had a radical surgical intervention on the uterus and the lymph nodes but in a different degree.


CONCLUSIONS
The method was successful in 67 (51.94%) of the patients included in the study. The factors influencing the success of the method were recorded.


CONCLUSIONS
The mapping method of detection of the sentinel lymph nodes could be utilized for patients with early stage of cervical cancer.
Khinkova
N
N
Gorchev
G
G
Tsvetkov
Ch
Ch
Tomov
S
S
D000328:Adult; D000368:Aged; D004396:Coloring Agents; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D011446:Prospective Studies; D012394:Rosaniline Dyes; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013194:Staining and Labeling; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery
D004396:Coloring Agents; D012394:Rosaniline Dyes; C008769:sulfan blue