title: Successful long-term deep brain stimulation for hemichorea-hemiballism in a patient with diabetes. Case report.
abstract: The authors report a case of hemichorea-hemiballism (HC-HB) that was successfully treated using deep brain stimulation (DBS). A 65-year-old right-handed man exhibited a sudden onset of right HC-HB without a diabetic coma. At admission T1-weighted magnetic resonance (MR) images revealed a high-intensity signal in the left striatum, contralateral to the patient's involuntary movements. The HC-HB continued for 5 months after onset of the condition despite medical treatment and a decreased intensity of the signal on T1-weighted MR images. The patient underwent placement of a quadripolar DBS electrode in the left thalamus, including the left ventral oralis (VO) anterior and posterior nuclei (the VO complex). Postoperatively, the right-sided HC-HB disappeared rapidly during electrical stimulation and there were no neurological deficits. The authors demonstrate that DBS can be an effective treatment for medically refractory HC-HB. This is the first case of HC-HB that has been successfully treated with DBS.
authors: Department of Neurosurgery, Kinki University, School of Medicine, Osaka-sayama, Osaka, Japan. nakano@neuro-s.med.kindai.ac.jp
authors: Naoki
authors: N
authors: Nakano
authors: Takuya
authors: T
authors: Uchiyama
authors: Takeshi
authors: T
authors: Okuda
authors: Masahiko
authors: M
authors: Kitano
authors: Mamoru
authors: M
authors: Taneda
mesh_terms: D000368:Aged; D002819:Chorea / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D046690:Deep Brain Stimulation; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D020820:Dyskinesias / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed