The mean platelet volume in patients with obesity.
Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [body mass index (BMI) > or =30 kg/m(2)] matched for age and gender. The MPV was significantly higher in obese group than in non-obese control group (10.3 +/- 1.2 vs. 9.0 +/- 0.8 fl, p < 0.01). MPV was positively correlated with BMI in obese group (p < 0.05). Increased MPV may be a possible cause for increased cardiovascular risk in patients with obesity.
Coban
E
E
Department of Internal Medicine, Akdeniz University Faculty of Medicine, 07070 Antalya, Turkey. ecoban@akdeniz.edu.tr
Ozdogan
M
M
Yazicioglu
G
G
Akcit
F
F
D000328:Adult; D001792:Blood Platelets / Q000473:pathology*; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D015539:Platelet Activation; D010976:Platelet Count; D012307:Risk Factors; D013923:Thromboembolism / Q000097:blood