[Role of clinical chemistry in the assessment and follow up of a diabetic patient].
Clinical chemistry is essential in the management of a patient with diabetes mellitus. It plays a major role in the diagnosis by measuring plasma glucose levels, in the fasting state or two hours after an oral glucose load. It helps in the definition of the type of diabetes by measuring plasma C-peptide concentration, a marker of residual endogenous insulin secretion, or by detecting islet cell antibodies, a marker of autoimmune disease. Finally, clinical chemistry is essential in assessing the quality of overall blood glucose control thanks to the dosage of glycated haemoglobin (HbA1c) and in demonstrating the adequate control of cardiovascular risk factors associated to the metabolic syndrome, especially dyslipidaemia.
Luyckx
F H
FH
Département de Biologie clinique, CHU Sart Tilman.
Castillo
M J
MJ
D015415:Biomarkers / Q000032:analysis; D001786:Blood Glucose / Q000032:analysis*; D002096:C-Peptide / Q000097:blood; D019963:Clinical Chemistry Tests; D048909:Diabetes Complications / Q000175:diagnosis; D003920:Diabetes Mellitus / Q000473:pathology*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans
D015415:Biomarkers; D001786:Blood Glucose; D002096:C-Peptide; D006442:Glycated Hemoglobin