title: Induction and memory of chirality in porphyrin hetero-aggregates: the role of the central metal ion.
abstract: The anionic H2TPPS porphyrin and its copper derivative, CuTPPS, form in aqueous solution hetero-aggregates with the cationic H2T4 porphyrin and its copper derivative, CuT4. In the presence of poly-L-glutamate, at pH 4.0, a CD signal appears in the Soret region of the spectrum, indicating that the polypeptide has induced chirality into the structure of the aggregates. These species exhibit remarkable inertness due to the strength and number of the coulombic interactions between the anionic and the cationic porphyrins. This property allows them to preserve the chiral structure, even when the matrix changes or loses its chiral conformation, demonstrating that these aggregates are capable of memorizing the chiral information. The remarkable properties of the title systems may find various applications (chiral amplification, discrimination, and separation) that, on the other hand, require a more strict control of the aggregate dimension. Here, we show that the central copper of these macrocycles is crucial for determining the aggregate dimension.
authors: Dipartimento di Scienze Chimiche, Viale A. Doria 6, Catania 95125, Italy.
authors: Angela
authors: A
authors: Mammana
authors: Massimo
authors: M
authors: De Napoli
authors: Rosaria
authors: R
authors: Lauceri
authors: Roberto
authors: R
authors: Purrello
mesh_terms: D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011166:Porphyrins; D003300:Copper