Physical activity and stress resistance: sympathetic nervous system adaptations prevent stress-induced immunosuppression.
A physically active lifestyle incurs many health benefits. One recently recognized benefit of regular moderate exercise is stress reduction. The current review develops the hypothesis that physical activity may prevent stress-induced suppression of the immune system and suggests an immunophysiological mechanism (sympathetic nervous system constraint) for this effect.
Fleshner
Monika
M
Department of Integrative Physiology and The Center for Neuroscience, University of Colorado at Boulder, CO 80309, USA. Fleshner@colorado.edu
D000222:Adaptation, Physiological / Q000276:immunology*; D000818:Animals; D004195:Disease Models, Animal; D015444:Exercise / Q000502:physiology; D006433:Hemocyanins / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology*; D007137:Immunoglobulin alpha-Chains / Q000276:immunology; D008019:Life Style; D009043:Motor Activity / Q000276:immunology*; D010805:Physical Conditioning, Animal / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013312:Stress, Physiological / Q000276:immunology*; D013564:Sympathetic Nervous System / Q000276:immunology*
D007137:Immunoglobulin alpha-Chains; D006433:Hemocyanins; C032808:keyhole-limpet hemocyanin