Cobalt-catalyzed efficient aziridination of alkenes.
[reaction: see text]. Cobalt porphyrins are capable of catalyzing the aziridination of alkenes with bromamine-T as the nitrene source. Among cobalt complexes of different porphyrins, Co(TDClPP) is an effective catalyst that can aziridinate a wide variety of alkenes. The catalytic system can operate at room temperature in a one-pot fashion with alkenes as limiting reagents, forming the desired N-sulfonylated aziridine derivatives in high to excellent yields with NaBr as the byproduct.
Gao
Guang-Yao
GY
Department of Chemistry, University of Tennessee, Knoxville, 37996-1600, USA.
Harden
Jeremiah D
JD
Zhang
X Peter
XP