title: Global fibrinolytic capacity in patients with subclinical hypothyroidism.
abstract: Subclinical hypothyroidism (SH) represents the earliest stages of hypothyroidism but the benefits of detecting and treating SH are not well known. The aim of this study was to evaluate the alterations in global fibrinolytic capacity (GFC), which indicates the overall fibrinolytic activity, in patients with SH. The study group comprised of 15 patients with SH and 15 healthy controls. The GFC was significantly lower in patients with SH than in control group (p<0.002). This result suggests a relative hypercoagulable state in SH.
authors: Department of Endocrinology and Metabolism, Faculty of Medicine, Trakya University, Edirne, Turkey.
authors: Sibel
authors: S
authors: Guldiken
authors: Muzaffer
authors: M
authors: Demir
authors: Burhan
authors: B
authors: Turgut
authors: Betul Ugur
authors: BU
authors: Altun
authors: Ender
authors: E
authors: Arikan
authors: Mujdat
authors: M
authors: Kara
mesh_terms: D000328:Adult; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D005342:Fibrinolysis; D006801:Humans; D007037:Hypothyroidism / Q000097:blood*; D018709:Statistics, Nonparametric; D013972:Thyrotropin; D013974:Thyroxine / Q000097:blood; D010959:Tissue Plasminogen Activator / Q000494:pharmacology; D014284:Triiodothyronine / Q000097:blood
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D014284:Triiodothyronine; D005337:Fibrin; D013972:Thyrotropin; D010959:Tissue Plasminogen Activator; D013974:Thyroxine