title: Thymic carcinoma in children.
abstract: Thymic epithelial neoplasms consist of thymomas, thymic carcinoids, and thymic carcinomas. Carcinomas are malignant tumors of the thymus characterized by obvious cytological anaplasia. They constitute only 4%-14% of thymic epithelial neoplams. Thymic carcinoma rarely occurs in children. Research in the English literature carried out for the present study revealed only 14 cases younger than 18 years-of-age. Here we have reported a 16-year old girl who presented with respiratory distress due to huge anterior mediastinal mass. Histological and immunohistochemical studies confirmed lymphoepithelioma-like thymic carcinoma. She received systemic chemotherapy and radiotherapy. However, she died within 15 months due to progressive disease.
authors: Department of Pediatric Oncology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey. nyaris@meds.ktu.edu.tr
authors: Nilgün
authors: N
authors: Yaris
authors: Yunus
authors: Y
authors: Nas
authors: Umit
authors: U
authors: Cobanoglu
authors: Melek N
authors: MN
authors: Yavuz
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D013945:Thymoma / Q000188:drug therapy / Q000473:pathology / Q000556:secondary; D013953:Thymus Neoplasms / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed