title: [Massive haemorrhage after dorsal decompressive laminectomy].
abstract: We describe a case of a massive haemorrhage after dorsal decompressive laminectomy. The biological syndrome was at first a disseminated intravascular coagulation (DIC), rapidly complicated by a secondary fibrinolysis. The usual treatment of DIC with plasma and platelet transfusion failed to control bleeding and the patient underwent four repeat operations for relapsing rapidly evolving paraplegia. Aprotinine treatment stopped the haemorrhage. The vertebral metastasis causing spinal compression proved to be of prostatic origin.
authors: Département d'anesthésie-réanimation, CHU Charles-Nicolle, rue de Germont, 76031 Rouen, France. Luc-Marie.Joly@chu.rouen.fr
authors: L-M
authors: LM
authors: Joly
authors: A
authors: A
authors: Sermet
authors: B
authors: B
authors: Turak
authors: C M
authors: CM
authors: Samama
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery*; D007611:Aprotinin / Q000627:therapeutic use; D019299:Decompression, Surgical / Q000009:adverse effects*; D004211:Disseminated Intravascular Coagulation; D005342:Fibrinolysis; D006470:Hemorrhage / Q000209:etiology* / Q000628:therapy*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D007796:Laminectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology / Q000517:prevention & control; D010949:Plasma; D017713:Platelet Transfusion; D011183:Postoperative Complications / Q000628:therapy*; D011471:Prostatic Neoplasms / Q000473:pathology; D012086:Reoperation; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*
chemical_list: D006490:Hemostatics; D007611:Aprotinin