C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions.
Cumpstey
Ian
I
Organic Chemistry, Lund University, Box 124, 221 00 Lund, Sweden.
Sundin
Anders
A
Leffler
Hakon
H
Nilsson
Ulf J
UJ
D001120:Arginine / Q000737:chemistry*; D001549:Benzamides / Q000737:chemistry*; D003198:Computer Simulation; D037502:Galectin 3 / Q000037:antagonists & inhibitors*; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013862:Thiogalactosides / Q000737:chemistry*
D001549:Benzamides; D037502:Galectin 3; D013862:Thiogalactosides; D001120:Arginine