Synthesis and biological evaluation of lipophilic iron chelators as protective agents from oxidative stress.
Lipophilic Fe(III) chelators were synthesized and shown to protect oligodendrial cells from oxidative damage induced by Fe(III) and hydrogen peroxide.
Yavin
Eylon
E
Department of Organic Chemistry, Weizmann Institute of Science, Rehovot, Israel.
Kikkiri
Raghavendra
R
Gil
Shosh
S
Arad-Yellin
Rina
R
Yavin
Ephraim
E
Shanzer
Abraham
A
D007502:Iron Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D008055:Lipids / Q000737:chemistry*; D018384:Oxidative Stress / Q000187:drug effects*
D007502:Iron Chelating Agents; D008055:Lipids