Multimodal imaging of somatosensory evoked cortical activity.
Somatosensory evoked cortical activity is well investigated in both fMRI and MEG/EEG. Investigation with functional magnetic resonance spectroscopic (fMRS) imaging is relatively new and provides a means to image the metabolic activity of the brain. We for the first time combined fMRS, fMRI, MEG and EEG. This provides information about the metabolic, hemodynamic and electrical activity of the brain and also the verification of one imaging modality with the other. The dipolar source localized from the EEG/MEG data is in the vicinity of the fMRI activation site and also in the same area where lactate consumption is high as measured with fMRS imaging.
Ramon
C
C
Department of Electrical Engineering, University of Washington, Seattle, WA 98195, USA. ceon@u.washington.edu
Haueisen
J
J
Richards
T
T
Maravilla
K
K
D004569:Electroencephalography / Q000187:drug effects / Q000379:methods*; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D019344:Lactic Acid / Q000494:pharmacology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015225:Magnetoencephalography / Q000187:drug effects / Q000379:methods*; D013003:Somatosensory Cortex / Q000187:drug effects / Q000502:physiology
D019344:Lactic Acid