Solution conformation of d(C(4)ACAC(4)TGT)(2); an intramolecularly folded i-motif from the insulin minisatellite.
A 28-mer sequence taken from the insulin minisatellite is shown, through NMR and UV thermal melting studies, to form an intramolecular i-motif with two ACA and one TGT loop that persists to near neutral pH and room temperature.
Jolad
Vandana V
VV
School of Chemistry, University of Leeds, Leeds, UK LS2 9JT.
Murad
Fatima K
FK
Arnold
John R P
JR
Fisher
Julie
J
D007328:Insulin / Q000737:chemistry* / Q000235:genetics; D018598:Minisatellite Repeats / Q000235:genetics*; D019906:Nuclear Magnetic Resonance, Biomolecular; D013056:Spectrophotometry, Ultraviolet
D007328:Insulin