Fatal sepsis and necrotizing pneumonia in a child due to community-acquired methicillin-resistant Staphylococcus aureus: case report and literature review.
Pediatric deaths due to community-acquired methicillin-resistant Staphylococcus aureus are rare. We describe the case of 2-y-old boy with fever and cough followed by comatose state with deteriorated respiration; the boy died of severe sepsis and necrotizing pneumonia. The etiological agent was community-acquired methicillin-resistant Staphylococcus aureus, carrying a type IV staphylococcal mecA gene cassette and the Panton-Valentine Leukocidin gene.
Tseng
Min-Hua
MH
Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Neihu, Taipei, Taiwan.
Wei
Bo-Huang
BH
Lin
Wei-Jen
WJ
Lu
Jang-Jih
JJ
Lee
Shih-Yi
SY
Wang
Sheng-Ru
SR
Chen
Shyi-Jou
SJ
Wang
Chih-Chien
CC
D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D005098:Exotoxins; D017809:Fatal Outcome; D006801:Humans; D007956:Leukocidins / Q000235:genetics; D008297:Male; D016106:Methicillin Resistance; D009336:Necrosis; D046915:Penicillin-Binding Proteins; D011023:Pneumonia, Staphylococcal / Q000188:drug therapy / Q000382:microbiology*; D018805:Sepsis / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus