Eosinophilic meningomyelitis in toxocariasis: case report and review of the literature.
Toxocariasis is a worldwide-occurring parasitic infection leading to tissue damage in various organs due to wandering Toxocara larvae (visceral larva migrans). More than 40 cases of CNS involvement in children and immunocompetent adults have been documented in detail to date. Here, we present evidence of eosinophilic meningomyelitis in an adult without known risk factors and with positive Toxocara antibody response in CSF, but not in blood. Toxocariasis has to remain among the differential diagnosis in patients with eosinophilic CNS infection even if serological tests in blood are negative. Adult cases seem to be more frequent than previously thought (about 60%).
Eberhardt
O
O
Department of Neurology, University of Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, Germany. oeberhardt@excite.com
Bialek
R
R
Nägele
T
T
Dichgans
J
J
D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000134:cerebrospinal fluid; D004802:Eosinophilia / Q000134:cerebrospinal fluid / Q000469:parasitology*; D006801:Humans; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000469:parasitology*; D009187:Myelitis / Q000134:cerebrospinal fluid / Q000469:parasitology*; D017166:Toxocara canis / Q000276:immunology; D014120:Toxocariasis / Q000175:diagnosis*
D000909:Antibodies, Helminth