title: Diagnosis of pelvic endometriosis with use of macroscopic versus histologic findings.
abstract: OBJECTIVE
  To obtain histologic confirmation of lesions suspected of endometriosis at laparoscopy.
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  Patients in an academic hospital.
  
  
  METHODS
  Women of reproductive age who complained of chronic pelvic pain.
  
  
  METHODS
  A total of 122 biopsies were obtained from 54 patients undergoing laparoscopy, after exclusion of other potential causes of pelvic pain.
  
  
  METHODS
  Lack of consistency between laparoscopic and histologic diagnosis of endometriosis, in particular for minimal/mild stages.
  
  
  RESULTS
  Endometriosis was confirmed by histology in 54% of the excised lesions. Diagnosis was more often confirmed among classic lesions than for all atypical lesions considered together. The histologic diagnosis of fibrosis was the most common among those biopsies, which lacked the presence of endometriosis. The revised American Fertility Association (AFS) scores before and after histologic confirmation differed significantly. In particular, 20 patients in either revised AFS class I or II were down-graded to stage 0. No single anatomical site turned out to be particularly prone to misdiagnosis at laparoscopy, in comparison to the other sites.
  
  
  CONCLUSIONS
  These results confirm the need of histologic confirmation to obtain a diagnosis of endometriosis. However, the clinical impact of such findings remains a matter of debate.
authors: Department of Obstetrics and Gynecology, S. Anna Hospital, University of Torino, Turin, Italy. gianluigi.marchino@unito.it
authors: Gian Luigi
authors: GL
authors: Marchino
authors: Gianluca
authors: G
authors: Gennarelli
authors: Raffaella
authors: R
authors: Enria
authors: Francesca
authors: F
authors: Bongioanni
authors: Giovanni
authors: G
authors: Lipari
authors: Marco
authors: M
authors: Massobrio
mesh_terms: D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D004715:Endometriosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods* / Q000706:statistics & numerical data; D017699:Pelvic Pain / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D018709:Statistics, Nonparametric