title: Diagnostic value of gadolinium-enhanced 3D magnetic resonance angiography in patients with suspected hepatic arterial complications after liver transplantation.
abstract: OBJECTIVE
  To evaluate the accuracy and clinical role of gadolinium-enhanced 3D magnetic resonance angiography (MRA) in patients with suspected hepatic arterial complications after liver transplantation.
  
  
  METHODS
  Thirty-six consecutive MRA studies were performed in 33 liver transplant recipients after transplantation. MRA image quality was assessed subjectively. Thirty-two MRA studies were retrospectively reviewed and correlated with surgery (n = 2), conventional angiography (n = 18), or clinical follow-up (n = 12). MRA findings were also correlated with those of Doppler sonography in 30 of the cases. In 20 cases, concordance between MRA and surgery or conventional angiography was evaluated for each grade of hepatic artery stenosis (normal, mild [<50%], moderate [50-75%], severe [>75%], or occluded).
  
  
  RESULTS
  MRA image quality was degraded 13 of 36 cases (36.1%) studies. The sensitivity, specificity, and accuracy of MRA by consensus reading for more than 50% of hepatic artery stenosis or occlusion were 67%, 90%, and 81.3%, respectively. Of the 19 cases in which Doppler sonography was abnormal, MRA correctly characterized hepatic artery stenosis in 16 (84.2%). MRA also correctly identified all 5 occurrences of celiac artery stenosis. However, MRA overestimated the severity of hepatic arterial stenosis in 3 (15%) of 20 cases and underestimated 5 (25%) of 20 cases.
  
  
  CONCLUSIONS
  MRA complements Doppler ultrasound to exclude significant hepatic artery stenosis. However, a substantial number of MRA studies were technically inadequate, and MRA demonstrated limited efficacy for correctly grading the severity of hepatic artery stenosis.
authors: Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, IA, USA. ishigamikousei@aol.com
authors: Kousei
authors: K
authors: Ishigami
authors: Alan H
authors: AH
authors: Stolpen
authors: Faraj M Hanna
authors: FM
authors: Al-Kass
authors: Yan
authors: Y
authors: Zhang
authors: Stephen C
authors: SC
authors: Rayhill
authors: Daniel A
authors: DA
authors: Katz
authors: Monzer
authors: M
authors: Abu-Yousef
mesh_terms: D000328:Adult; D003251:Constriction, Pathologic / Q000175:diagnosis; D005260:Female; D005682:Gadolinium; D006499:Hepatic Artery / Q000473:pathology*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013927:Thrombosis / Q000175:diagnosis*; D018608:Ultrasonography, Doppler; D014652:Vascular Diseases / Q000175:diagnosis*
chemical_list: D005682:Gadolinium