2nd FY Khoo Memorial Lecture. Brachytherapy--one man's meat, a personal journey in radiation oncology.
The Lecture covers the author's personal experience in brachytherapy in radiation oncology, beginning with low-dose rate (LDR) treatments using 226Ra "hot" sources, in the 1960s and early 1970s, through manual afterloading for treating gynaecological cancers with the same sources in the 1970s and 1980s, to high-dose rate (HDR) remote afterloading on a microSelectron HDR machine, from 1989 on. This progression in brachytherapy is discussed, and specific applications to various tumour sites are presented, including long-term results of a personal series of 106 patients with cancer of the uterine cervix, treated with radiotherapy incorporating HDR brachytherapy. The Lecture rounds off with an unusual case of equine sarcoid, treated with a postoperative implant, using 192Ir LDR brachytherapy.
Khor
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Mount Elizabeth Oncology Centre, 3 Mount Elizabeth, Singapore 228510.
D000818:Animals; D001918:Brachytherapy / Q000009:adverse effects; D005142:Eyelid Neoplasms / Q000532:radiotherapy / Q000662:veterinary; D005260:Female; D005354:Fibrosarcoma / Q000532:radiotherapy / Q000662:veterinary; D005770:Gastrointestinal Neoplasms / Q000532:radiotherapy; D005833:Genital Neoplasms, Female / Q000401:mortality / Q000532:radiotherapy; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006734:Horse Diseases / Q000532:radiotherapy; D006736:Horses; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage