title: Glutathione-S-transferase polymorphism and clinical features of acute drug poisoning in children.
abstract: We studied the association of GSTM1 and GSTT1 and GSTP1 Ile105-Val105 polymorphism with the duration of intoxication, polyorgan failure, and severity of drug poisoning in children. The combination of GSTM1 and GSTT1 zero genotypes is a favorable sign for the duration of intoxication and severity of the disease.
authors: Institute of Molecular Biology and Biophysics, Siberian Division of Russian Academy of Medical Sciences, Russia. drugsmet@soramn.ru
authors: V A
authors: VA
authors: Vavilin
authors: O G
authors: OG
authors: Safronova
authors: N A
authors: NA
authors: Manankin
authors: L F
authors: LF
authors: Kaznacheeva
authors: V V
authors: VV
authors: Lyakhovich
mesh_terms: D002648:Child; D016001:Confidence Intervals; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D016017:Odds Ratio; D011041:Poisoning / Q000201:enzymology / Q000235:genetics*; D011110:Polymorphism, Genetic
chemical_list: D005982:Glutathione Transferase