title: [The effects of hyperventilation upon spinal dorsal horn neuronal single-unit activities under nitrous oxide anesthesia].
abstract: BACKGROUND
  The purpose of this study is to investigate the effects of hyperventilation upon spinal dorsal horn neuronal single-unit activities under nitrous oxide anesthesia.
  
  
  METHODS
  Eight decerebrated spinal cats with laminectomy were maintained with oxygen and pancuronium bromide. Following the control period of normocapnia, 50% nitrous oxide was administered for 30 minutes after a hypocapnia period of 20-25 mmHg for 20 minutes. The recoveries of activities followed with normocapnia and pure oxygen administration. The changes of spontaneous and evoked activities by the pinching were investigated every 5 minutes after control study.
  
  
  RESULTS
  Inhalation of 50% nitrous oxide suppressed the WDR neuronal activities and with hyperventilation the suppressions significantly increased.
  
  
  CONCLUSIONS
  These results were compatible with clinical reports on the effectiveness of hyperventilation as a maintenance method under N2O anesthesia.
authors: Department of Anesthesiology, Toho University Sakura Hospital, Sakura.
authors: Yasuo
authors: Y
authors: Ide
authors: Megumu
authors: M
authors: Tagami
authors: Toshinobu
authors: T
authors: Sumida
authors: Kazuo
authors: K
authors: Hanaoka
mesh_terms: D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D005260:Female; D006985:Hyperventilation / Q000503:physiopathology*; D008297:Male; D009609:Nitrous Oxide / Q000494:pharmacology*; D020671:Posterior Horn Cells / Q000503:physiopathology*
chemical_list: D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide