Rapid method for diagnosis of abnormal activity of butyrylcholinesterase.
We present the results of spectral studies of the interactions between butyrylcholinesterase and ethidium bromide fluorophore inhibitor. The ethidium bromide fluorescence selectively increased in the presence of butyrylcholinesterase. A rapid method for evaluation of serum butyrylcholinesterase activity is developed.
Vlaskin
D N
DN
Physical Faculty, M. V. Lomonosov Moscow State University.
Gainullina
E T
ET
Ryzhikov
S B
SB
Taranchenko
V F
VF
D002091:Butyrylcholinesterase / Q000097:blood* / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D003933:Diagnosis; D004996:Ethidium / Q000737:chemistry / Q000494:pharmacology; D005456:Fluorescent Dyes / Q000494:pharmacology; D006801:Humans; D013050:Spectrometry, Fluorescence / Q000379:methods*
D002800:Cholinesterase Inhibitors; D005456:Fluorescent Dyes; D002091:Butyrylcholinesterase; D004996:Ethidium