Immunization of mice with concentrated liquor from male zooid of Antheraea pernyi.
OBJECTIVE
To study the effects of concentrated liquor from male zooid of Antheraea pernyi on immunological mice.


METHODS
For each experiment, 40 mice were randomly divided into normal saline group (control group) and three tested groups that were administered different dosages of concentrated liquor from male zooid of A. pernyi and food for 15 d. The typical FSR and HC(50) value, monocyte-phagocytic exponent K and emendated monocyte-phagocytic exponent alpha were determined and calculated respectively.


RESULTS
After 24 and 48 h, the FSR values of the three tested groups improved significantly in comparison to the control group by variance analysis. The HC(50) values showed a significant difference between the high dosage group and the control group, as well as between the high dosage group and other two tested groups. The monocyte-phagocytic exponent K and emendated exponent alpha showed rising tendencies, but no significant differences were found by variance analysis.


CONCLUSIONS
The concentrated liquor from male zooid of A. pernyi can significantly enhance cellular and humoral immune function in mice, but has no distinct influence on the monocyte-phagocytic system in mice.
Li
Sheng
S
Shandong Tumor Hospital, Jinan 250117, Shandong Province, China.
Zhang
Bo
B
Zhang
Wei-Dong
WD
Ma
Ting-Hang
TH
Huang
Yong
Y
Yi
Long-Hai
LH
Yu
Jin-Ming
JM
D000818:Animals; D007107:Immune System / Q000187:drug effects*; D007114:Immunization; D019476:Insect Proteins / Q000276:immunology / Q000494:pharmacology*; D008297:Male; D008516:Medicine, Chinese Traditional; D051379:Mice; D008815:Mice, Inbred Strains; D009036:Moths
D019476:Insect Proteins