Maternal care and development of stress responses in baboons.
The ability to mount a successful response to threats is critical for an organism's survival. A key element of the stress response is its nonspecificity toward the stress source, with similar endocrine and behavioral changes expected under a variety of stressors. In this project we utilized an experimental design that accounts for multiple sources of variation to further understand the nature of stress responsivity and its relationship to the early rearing environment. A sample of baboons (n=73) was observed during the early phase of life in their social group, and then tested as juveniles in a challenging situation. Maternal cortisol levels were measured during the peripartum period. The challenging situation (individuals were isolated for a few minutes in a single cage) was designed to be a moderate source of psychological stress. Patterns in individual differences during the stress test were "mapped" by means of multidimensional scaling (MDS). After the observation was made, the subject was sedated and a blood sample was taken to measure cortisol levels. Our results indicate that when juvenile baboons are confronted with a source of psychological stress, they show a multidimensional behavioral response, probably mediated by the activation and synergic interaction among different neurohormonal systems that, ultimately, act on the hypothalamus-pituitary-adrenal (HPA) axis. Different components of the multidimensional, or nonspecific, behavioral response are associated with the quality and quantity of interactions with their mothers during early life. Juveniles whose mothers displayed higher levels of positive interaction were characterized by vigilant but less active reactions to the stress test, whereas juveniles of mothers that displayed high levels of stress-related behaviors had higher cortisol and locomotion levels.
Bardi
Massimo
M
Department of Comparative Medicine, Southwest Foundation for Biomedical Research, PO Box 760549, San Antonio, TX 78245, USA. mbardi@icarus.sfbr.org
Bode
Anne E
AE
Ramirez
Stephanie M
SM
Brent
Linda Y
LY
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D005260:Female; D006608:Hierarchy, Social; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008425:Maternal Behavior / Q000502:physiology*; D019370:Observation; D010215:Papio / Q000502:physiology*; D011863:Radioimmunoassay; D012044:Regression Analysis; D013312:Stress, Physiological / Q000523:psychology*
D006854:Hydrocortisone