title: Typical ECG changes unmasked by ajmaline in a patient with Brugada syndrome and left bundle branch block.
abstract: Brugada syndrome is a channelopathy associated with right bundle branch block and ST segment elevation in the right precordial leads. These electrocardiographic signs may not be apparent most of the time but can be unmasked by certain antiarrhythmic agents. Until now, all of the reports on this syndrome have focused on patients with no significant intraventricular conduction delay at baseline electrograms. In this report, we describe a patient with Brugada syndrome with left bundle branch block at baseline ECG. After intravenous ajmaline, the patient developed right bundle branch block and ST segment elevations in the right precordial leads.
authors: Department of Cardiology, School of Medicine, Bakent University, Ankara, Turkey. bozin@tr.net
authors: Bülent
authors: B
authors: Ozin
authors: Ilyas
authors: I
authors: Atar
authors: Bülent
authors: B
authors: Altunkeser
authors: Cağatay
authors: C
authors: Ertan
authors: Aylin
authors: A
authors: Yildirir
authors: Haldun
authors: H
authors: Müderrisoğlu
mesh_terms: D000328:Adult; D000404:Ajmaline / Q000494:pharmacology*; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D002037:Bundle-Branch Block / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D005260:Female; D006801:Humans; D013577:Syndrome; D014693:Ventricular Fibrillation / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D000404:Ajmaline