title: Two patients with different features of congenital optic disc anomalies in the two eyes.
abstract: OBJECTIVE
  Description of two patients, each with different features of congenital optic disc anomalies in the two eyes.
  
  
  METHODS
  Case report
  
  
  RESULTS
  Patient 1, a 3-month-old girl, showed retinochoroidal coloboma involving the optic nerve in the right eye and optic nerve hypoplasia in the left eye. Patient 2, a 5-month-old boy, showed retinal fold extending inferiorly in the right eye and optic disc coloboma in the left eye.
  
  
  CONCLUSIONS
  Since in both cases coloboma was seen in one eye, the optic nerve hypoplasia or retinal fold in the fellow eye of these two patients may have been related to the timing of embryonic fissure opening or closing.
authors: Department of Ophthalmology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
authors: Yumi
authors: Y
authors: Suzuki
authors: Eriko
authors: E
authors: Kawase
authors: Sachiko
authors: S
authors: Nishina
authors: Noriyuki
authors: N
authors: Azuma
mesh_terms: D002829:Choroid / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology; D003103:Coloboma / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007223:Infant; D008297:Male; D009898:Optic Disk / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D012160:Retina / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology; D014463:Ultrasonography