Yolk sac tumor in a young girl: a case report.
BACKGROUND
Yolk sac tumor is a rare neoplasm characterized by high malignancy given its premature metastasis, that is frequent in adolescence.


METHODS
A 21-year-old woman came to our observation for an ovarian cyst (13 cm in diameter). Following salpingo-oophorectomy, it was revealed as a yolk sac tumor by histological diagnosis. The patient exhibited a highly elevated level of alpha1-fetoprotein (AFP) (1156 UI/ml). She is now undergoing chemotherapy treatment.


CONCLUSIONS
This is an interesting case of yolk sac tumor in a young girl, at an age typical for germ cell tumor. AFP represents a valid marker resulting in a useful diagnostic tool.
Razzi
Sandro
S
Department of Pediatric, Obstetric and Reproductive Medicine, University of Siena, Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy.
Luisi
Stefano
S
Gabbanini
Massimo
M
Lazzeri
Lucia
L
Mazzini
Massimo
M
Petraglia
Felice
F
D000328:Adult; D000970:Antineoplastic Agents; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D010052:Ovariectomy
D000970:Antineoplastic Agents