title: What makes MUC1 a tumor antigen?
abstract: The epithelial mucin 1 (MUC1) is an accepted serum tumor marker and cellular tumor antigen. We discuss recent views on the difference(s) between normal and tumor MUC1, and its implication for the development of cancer vaccines and antibody therapies, with special emphasis on the role of glycosylation.
authors: Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany. uwe.karsten@glycotope.com
authors: Uwe
authors: U
authors: Karsten
authors: Silvia
authors: S
authors: von Mensdorff-Pouilly
authors: Steffen
authors: S
authors: Goletz
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000502:physiology*; D014408:Biomarkers, Tumor; D019496:Cancer Vaccines; D006801:Humans; D018396:Mucin-1 / Q000502:physiology*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D019496:Cancer Vaccines; D018396:Mucin-1