A prospective, randomized trial of Acticoat versus silver sulfadiazine in the treatment of partial-thickness burns: which method is less painful?
Despite recent improvements in analgesia, pain control during dressing changes continues to be a major challenge in patients with burns. We investigated two different dressing modalities to compare how much pain the patient experienced during and after the dressing change. Patients with partial-thickness burns that required only topical wound care were assigned randomly to treatment with Acticoat (Smith and Nephew USA, Largo, FL) or silver sulfadiazine (AgSD). The outcome variable was pain during wound care, which was measured using visual analog pain scores. The mean visual analog pain scores for the wounds treated with Acticoat or AgSD wounds were 3.2 and 7.9, respectively (P < .0001; paired Student's t-test). In 41 of the 47 paired pain score observations, the pain in the wound treated with AgSD was perceived as greater than in the wound treated with Acticoat. Burn wound care with Acticoat is less painful than burn wound care with AgSD in patients with selected partial-thickness burns.
Varas
Robin Prater
RP
DeWitt Daughtry Family Department of Surgery, University of Miami/Jackson Memorial Burn Center, Miami, FL 33101, USA.
O'Keeffe
Terence
T
Namias
Nicholas
N
Pizano
Louis R
LR
Quintana
Olga Delia
OD
Herrero Tellachea
Marlene
M
Rashid
Qammar
Q
Ward
C Gillon
CG
D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects; D001458:Bandages / Q000009:adverse effects; D002056:Burns / Q000150:complications* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis / Q000209:etiology*; D010147:Pain Measurement; D017060:Patient Satisfaction; D011091:Polyesters / Q000008:administration & dosage* / Q000009:adverse effects; D011095:Polyethylenes / Q000008:administration & dosage* / Q000009:adverse effects; D011446:Prospective Studies; D012837:Silver Sulfadiazine / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
C117408:Acticoat; D000891:Anti-Infective Agents, Local; D011091:Polyesters; D011095:Polyethylenes; D012837:Silver Sulfadiazine