title: Heritable diseases of the blood vessels.
abstract: Four inherited disorders known to effect major arteries will be discussed, including Marfan syndrome (MS), Ehlers-Danlos syndrome (EDS), bicuspid aortic valve (BAV) and nonsyndromic familial aortic dissection. Recent advances in understanding their pathophysiology are presented, and how this knowledge impacts on diagnosis, prevention and treatment is discussed.
authors: University of Nebraska Medical Center, Omaha, NE 68132, USA. btbaxter@unmc.edu
authors: B Timothy
authors: BT
authors: Baxter
mesh_terms: D000784:Aortic Dissection / Q000235:genetics*; D000818:Animals; D001014:Aortic Aneurysm / Q000235:genetics*; D017545:Aortic Aneurysm, Thoracic / Q000235:genetics; D001018:Aortic Diseases / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D001022:Aortic Valve Insufficiency / Q000235:genetics; D003094:Collagen / Q000235:genetics / Q000378:metabolism; D004535:Ehlers-Danlos Syndrome / Q000235:genetics* / Q000628:therapy; D000071837:Fibrillins; D020022:Genetic Predisposition to Disease; D006801:Humans; D008382:Marfan Syndrome / Q000235:genetics* / Q000628:therapy; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism; D010641:Phenotype
chemical_list: D000071837:Fibrillins; D008840:Microfilament Proteins; D003094:Collagen