Effectiveness of chemotherapy in melanotic neurectodermal tumor of infancy.
MNTI is an uncommon tumor mainly of infants. Surgery is the primary modality of treatment. Chemotherapy has been tried for recurrent/residual tumors. The chemotherapeutic response of 3 infants treated at a center is discussed here. All 3 infants showed good response to chemotherapy. In 2 of them complete residual tumor resection became possible; 2 of them are alive and tumor regression continues. One child had local recurrence later and was lost for follow-up.
Kumari
T Priya
TP
Division of Paediatric Oncology, Department of Imageology, Regional Cancer Centre, Thriuvananthapuram 695 011, Kerala State, India. rcctvm@md2.vsnl.net.in
Venugopal
M
M
Mathews
Anitha
A
Kusumakumary
P
P
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local; D018365:Neoplasm, Residual / Q000188:drug therapy* / Q000601:surgery; D017600:Neuroectodermal Tumor, Melanotic / Q000188:drug therapy* / Q000601:surgery; D009918:Orbital Neoplasms / Q000188:drug therapy* / Q000601:surgery; D010858:Pigmentation; D012888:Skull Neoplasms / Q000188:drug therapy* / Q000601:surgery; D013701:Temporal Bone / Q000473:pathology*; D016896:Treatment Outcome