title: Oral androstenedione-induced impotence and severe oligospermia.
abstract: OBJECTIVE
  To report a case of androstenedione (A)-induced impotence and severe oligospermia.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Multispecialty tertiary referral center.
  
  
  METHODS
  A 29-year-old married male recreational bodybuilder using the legal dietary supplement A in an attempt to enhance athletic performance.
  
  
  METHODS
  Immediate cessation of oral A, Depo-T regimen with a taper, administered during 3 months, to alleviate loss of libido and impotence.
  
  
  METHODS
  Resolution of symptoms and normalization of semen parameters.
  
  
  RESULTS
  Resolution of symptoms and normalization of semen parameters at 6 months, and successful intrauterine pregnancy achieved 1 year after initial presentation.
  
  
  CONCLUSIONS
  Oral A has a previously unrecognized side effect, which is the potential to suppress the hypothalamic pituitary gonadal axis.
authors: Division of Urology, Scott and White Memorial Hospital and Clinic, Scott, Sherwood & Brindley Foundation, The Texas A&M University System Health Science Center College of Medicine, Temple, Texas, USA.
authors: Robert H
authors: RH
authors: Ritter
authors: Anthony K
authors: AK
authors: Cryar
authors: Michael R
authors: MR
authors: Hermans
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000735:Androstenedione / Q000008:administration & dosage* / Q000009:adverse effects*; D007172:Erectile Dysfunction / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000735:Androstenedione