Elevated plantar pressures in neuropathic diabetic patients with claw/hammer toe deformity.
Elevated plantar foot pressures during gait in diabetic patients with neuropathy have been suggested to result, among other factors, from the distal displacement of sub-metatarsal head (MTH) fat-pad cushions caused by to claw/hammer toe deformity. The purpose of this study was to quantitatively assess these associations. Thirteen neuropathic diabetic subjects with claw/hammer toe deformity, and 13 age- and gender-matched neuropathic diabetic controls without deformity, were examined. Dynamic barefoot plantar pressures were measured with an EMED pressure platform. Peak pressure and force-time integral for each of 11 foot regions were calculated. Degree of toe deformity and the ratio of sub-MTH to sub-phalangeal fat-pad thickness (indicating fat-pad displacement) were measured from sagittal plane magnetic resonance images of the foot. Peak pressures at the MTHs were significantly higher in the patients with toe deformity (mean 626 (SD 260)kPa) when compared with controls (mean 363 (SD 115) kPa, P<0.005). MTH peak pressure was significantly correlated with degree of toe deformity (r=-0.74) and with fat-pad displacement (r=-0.71) (P<0.001). The ratio of force-time integral in the toes and the MTHs (toe-loading index) was significantly lower in the group with deformity. These results show that claw/hammer toe deformity is associated with a distal-to-proximal transfer of load in the forefoot and elevated plantar pressures at the MTHs in neuropathic diabetic patients. Distal displacement of the plantar fat pad is suggested to be the underlying mechanism in this association. These conditions increase the risk for plantar ulceration in these patients.
Bus
Sicco A
SA
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, P.O.Box 22700, 1100DE, Amsterdam, The Netherlands. s.a.bus@amc.uva.nl
Maas
Mario
M
de Lange
Antony
A
Michels
Robert P J
RP
Levi
Marcel
M
D017719:Diabetic Foot / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005528:Foot / Q000503:physiopathology*; D005684:Gait; D037801:Hammer Toe Syndrome / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011312:Pressure