[A charge-deficient analogue of spermine with chelating properties].
1,12-Diamino-3,6,9-triazadodecane, a new isosteric and charge-deficient analogue of spermine, is synthesized. Unlike spermine, the new analogue is an excellent chelator of Cu2+ ions. Possible applications of this compound for studying enzymes of polyamine metabolism and cellular functions of spermine are discussed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 3; see also http://www.maik.ru.
Khomutov
A R
AR
Grigorenko
N A
NA
Demin
A V
AV
Vepsalainen
J
J
Casero
R A
RA
Woster
P M
PM
D002614:Chelating Agents / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D013096:Spermine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
C502960:1,12-diamino-3,6,9-triazadodecane; D002614:Chelating Agents; D013096:Spermine; D003300:Copper