title: Age dependence of diffusion-weighted magnetic resonance imaging findings in maple syrup urine disease encephalopathy.
abstract: A patient with maple syrup urine disease (MSUD) who developed encephalopathy twice and underwent magnetic resonance examinations, including diffusion-weighted (DW) imaging, is presented. Areas of abnormal intensity on DW images dramatically differed between the initial and second attacks, apparently attributable to the difference in myelination. Our observation demonstrates the age dependence of DW imaging findings in MSUD encephalopathy attributable to progression of myelination and would help in the proper diagnosis of MSUD encephalopathy at any age.
authors: Department of Radiology, Osaka National Hospital, Osaka 540-0006, Japan. s-mio@onh.go.jp
authors: Mio
authors: M
authors: Sakai
authors: Yusuke
authors: Y
authors: Inoue
authors: Hiroshi
authors: H
authors: Oba
authors: Akira
authors: A
authors: Ishiguro
authors: Kyoko
authors: K
authors: Sekiguchi
authors: Yoshihiko
authors: Y
authors: Tsukune
authors: Masanori
authors: M
authors: Mitomo
authors: Hironobu
authors: H
authors: Nakamura
mesh_terms: D000367:Age Factors; D001927:Brain Diseases / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008375:Maple Syrup Urine Disease / Q000175:diagnosis / Q000473:pathology*