Hereditary skeletal muscle diseases in the horse. A review.
Since riders nowadays are expecting the highest level of performance from their horses, muscular disorders therefore represent a major problem for the equine athlete. A lot of research has been done to identify muscular disorders and their etiopathogenesis. Both acquired and inherited forms of muscle diseases have been described. In this review only the latter forms will be mentioned. Major signs of all muscle disorders are muscular stiffness, cramping or pain, muscular fasciculations, muscular atrophy and exercise intolerance. Muscle biopsies can help to identify the cause of rhabdomyolysis or muscular atrophy. However, especially in hereditary muscular diseases, a lot of questions are still to be answered. Increasing knowledge of the etiopathogenesis and newer diagnostic tests may lead to a more accurate diagnosis of the individual diseases in future.
Nollet
H
H
Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium. Heidi.Nollet@UGent.be
Deprez
P
P
D000818:Animals; D006008:Glycogen Storage Disease / Q000503:physiopathology / Q000662:veterinary; D006734:Horse Diseases / Q000235:genetics* / Q000503:physiopathology; D006736:Horses; D017240:Mitochondrial Myopathies / Q000503:physiopathology / Q000662:veterinary; D009135:Muscular Diseases / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*; D009224:Myotonia Congenita / Q000503:physiopathology / Q000662:veterinary; D020513:Paralysis, Hyperkalemic Periodic / Q000503:physiopathology / Q000662:veterinary; D012206:Rhabdomyolysis / Q000503:physiopathology / Q000662:veterinary