Pseudoporphyria induced by voriconazole.
Pseudoporphyria is an uncommon blistering disorder with clinical and histologic similarities to porphyria cutanea tarda but which lacks urine and serum porphyrin elevations. Pseudoporphyria has been linked with numerous causes including chronic renal failure, ultraviolet radiation, and numerous medications. We report a case of pseudoporphyria attributed to the relatively new triazole antifungal agent voriconazole. This medication has not been previously identified as a cause of pseudoporphyria.
Sharp
Misty T
MT
Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Horn
Thomas D
TD
D000935:Antifungal Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011164:Porphyrias / Q000139:chemically induced*; D011743:Pyrimidines / Q000009:adverse effects*; D014230:Triazoles / Q000009:adverse effects*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole