[The inherent liability to infection of various tissue for urethra reconstruction].
OBJECTIVE
Observing the long-term results of reconstructed urethra to reduce the postop infection rate of hypospadias. To explore the standard of selecting tissue for urethra reconstruction by comparing the different inherent liability to infection in use of different kinds of tissue for urethra reconstruction.


METHODS
Neo-urethra inner wall and normal urethra were observed through urography and urethroscope. The tissue section of neo-urethra, normal urethra and tissue for urethra reconstruction were observed through light microscope, scanning electron microscope and transmission electron microscope.


RESULTS
The structure and liability to infection of neo-urethra made of bladder mucosa, buccal mucosa or skin never changed after long time. Metaplasia never took place in neo-urethra.


CONCLUSIONS
The structure and liability to infection of neo-urethra were the same as those of the congeneric tissue. Bladder or buccal mucosa is the best tissue for urethra reconstruction considering urethra microenvironment. Neo-urethra made of skin is more liable to infection by nature. The best opportunity of hypospadias operation should be before puberty.
Fan
Ju-Feng
JF
Plastic Surgery Hospital of CAMS, Beijing 100041, China.
Li
Yang-Qun
YQ
Liu
Li-Qiang
LQ
Li
Qiang
Q
Wang
Yong-Qian
YQ
Xu
Jia-Jie
JJ
Chen
Wen
W
Li
Sen-Kai
SK
D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007021:Hypospadias / Q000601:surgery*; D007223:Infant; D007239:Infections / Q000209:etiology*; D008297:Male; D009061:Mouth Mucosa / Q000637:transplantation; D016038:Skin Transplantation; D016896:Treatment Outcome; D014521:Urethra / Q000601:surgery*; D055815:Young Adult
D001672:Biocompatible Materials