Spectral characterization of two bioaccumulated methoxylated polybrominated diphenyl ethers.
Two methoxylated polybrominated diphenyl ethers (MeO-PBDEs) were isolated from a True's beaked whale (Mesoplodon mirus) and identified by NMR (1H, 1H-1H and 1H-13C) and high resolution mass spectrometry as 2-(2',4'-dibromophenoxy)-3,5-dibromoanisole (6-MeO-BDE47) and 2-(2',4'-dibromophenoxy)-4,6-dibromoanisole (2'-MeO-BDE68). Previously the structures of these bioaccumulated compounds have been determined by comparison of their mass spectra and gas chromatographic (GC) retention times with those of authentic standards. While this method is accepted and generally successful, NMR of the isolated compounds allows us to definitively identify the congeners. Our characterizations are consistent with those made for MeO-PBDEs in other organisms, identified by chromatographic methods.
Teuten
Emma L
EL
Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. eteuten@whoi.edu
Johnson
Carl G
CG
Mandalakis
Manolis
M
Asplund
Lillemor
L
Gustafsson
Orjan
O
Unger
Maria
M
Marsh
Göran
G
Reddy
Christopher M
CM
D000273:Adipose Tissue / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D001711:Biotransformation; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D010647:Phenyl Ethers / Q000302:isolation & purification* / Q000493:pharmacokinetics; D011075:Polybrominated Biphenyls / Q000302:isolation & purification* / Q000493:pharmacokinetics; D014874:Water Pollutants, Chemical / Q000302:isolation & purification* / Q000493:pharmacokinetics; D014907:Whales / Q000378:metabolism*
D010647:Phenyl Ethers; D011075:Polybrominated Biphenyls; D014874:Water Pollutants, Chemical