title: [Clinical study on effect of quyu xiaoban capsule on regression of atherosclerosis].
abstract: OBJECTIVE
  To study the effect of Quyu Xiaoban capsule (QXC) on regression and stabilization of atherosclerotic plaque with high-frequency ultrasound technique.
  
  
  METHODS
  Eighty patients with atherosclerosis (AS) were randomly divided into the treated group and the control group, level of blood lipids was measured, and intima-media thickness (IMT) and corrected value of image average echo intensity (AIIc%) were determined by ultrasound technique at the beginning of experiment and after being treated for six months.
  
  
  RESULTS
  The levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) were significantly decreased in the treated group after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37, P<0.05). The AIIc% of fatty atherosclerotic plaque was significantly increased after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37), and the change rate of AIIc% in the treated group was significantly different to that in the control group (10.9 +/- 5.1% vs 2.5 +/- 5.5%, P < 0.05).
  
  
  CONCLUSIONS
  QXC can significantly lower the blood lipids level, delay the progress and enhance the stability of atherosclerotic plaque.
authors: Institute of Diagnostics, Medical College, Shandong University, Jinan 250012. liuyf@sdu.edu.cn
authors: Yun-fang
authors: YF
authors: Liu
authors: Yu-xia
authors: YX
authors: Zhao
authors: Hui-ming
authors: HM
authors: Yu
mesh_terms: D000328:Adult; D000368:Aged; D050197:Atherosclerosis / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000473:pathology; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D014463:Ultrasonography
chemical_list: D008078:Cholesterol, LDL; D004365:Drugs, Chinese Herbal; D002784:Cholesterol