title: [The polymorphism of Y chromosome and mtDNA distribution among two Bai populations].
abstract: In the same ethnic group, people residing at different places may have genetic difference. The difference can be the results of migration and admixture events happened in history. To clarify the genetic relationship and micro-evolution of two Bai ethnic populations residing in Yunnan and Hunan province respectively,we investigated their genetic difference from paternal and maternal genealogy with six other ethnic groups as outgroups. Fourteen loci from mtDNA and thirteen loci from Y chromosome were selected for genotyping using PCR-RFLP methods. Result showed that H6 and H8 are the same dominant Y chromosome haplotypes in two Bai groups. However,the distribution of mtDNA haplogroups showed difference between two Bai populations. D, B, M8 are the predominant haplogroups in Hunan Bai ethnic population, whereas M, G, F are dominant in Yunnan Bai ethnic population. Principal Component (PC) analysis based on the Y chromosome haplotypes showed that two Bai ethic populations cluster together. It shows a close paternal genetic relationship between two Bai ethnic populations. From the mtDNA PC plot, it is clear that Hunan Bai is close to Hunan Han and Tujia, whereas Yunnan Bai is close to ethnic groups living in Yunnan province. The difference of mtDNA haplogroup distribution in two Bai people may reflect the maternal gene flow between ethnic groups living in Hunan province after the ancestors of Hunan Bai migrated from Yunnan province to Hunan province 800 years ago.
authors: Human Genetics Center of Yunnan University, Kunming 650091, China.
authors: Yong-Li
authors: YL
authors: Dong
authors: Lu
authors: L
authors: Gao
authors: Xiao-Xia
authors: XX
authors: Yang
authors: Bo
authors: B
authors: Wen
authors: Zhi-Li
authors: ZL
authors: Yang
authors: Wen-Ru
authors: WR
authors: Tang
authors: Bao-Wen
authors: BW
authors: Cheng
authors: Bing-Rong
authors: BR
authors: Zheng
authors: Kai-Yuan
authors: KY
authors: Li
authors: Chun-Jie
authors: CJ
authors: Xiao
mesh_terms: D044466:Asian People / Q000208:ethnology / Q000235:genetics; D002681:China; D041322:Chromosomes, Human, Y / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D025341:Principal Component Analysis
chemical_list: D004272:DNA, Mitochondrial