Repetitive transcranial magnetic stimulation: a possible novel therapeutic approach to eating disorders.
The two most common eating disorders, anorexia nervosa and bulimia nervosa, are characterized by aberrant eating patterns and disturbances in body image. Treatment involves combining individual, behavioural, group, and family therapies, possibly with medications. Studies have found that medication, chiefly antidepressants, could be of help in bulimia nervosa but the evidence is weaker for use in anorexia nervosa. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique that briefly stimulates or depresses cortical areas within the brain. It has been used in the treatment of various psychiatric disorders, especially major depression, which is a condition that patients with eating disorders often experience as a significant comorbidity. Given that both disorders may share a common pathogenesis, this report proposes that rTMS may represent an alternative strategy for the treatment of eating disorders. Other evidence that supports this notion comes from animal studies that show that rTMS can change feeding behaviours and central neurotransmitters related to the regulation of eating behaviours. Further investigation into the dose, duration and type of rTMS stimulus is needed to verify the efficacy of this intervention in eating disorders.
Tsai
Shih-Jen
SJ
Department of Psychiatry, Taipei Veterans General Hospital, Taiwan Division of Psychiatry, School of Medicine, National Yang-Ming University, No. 201 Shih-Pai Road, Sec. 2, 11217 Taipei, Taiwan. sjtsai@vghtpe.gov.tw
D000818:Animals; D001921:Brain / Q000503:physiopathology*; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D005247:Feeding Behavior; D001068:Feeding and Eating Disorders / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008954:Models, Biological; D050781:Transcranial Magnetic Stimulation / Q000379:methods*