92nd AACR. Anti-angiogenic agents.
This year's meeting covered a vast number of subjects of which a few warrant specific discussion due to current interest. Research activities are expanding in the potential use of anti-angiogenic and antivascular targeting agents for treatment of cancer. Studies on the mechanisms of action of this wide variety of agents remain the focus of attention. A large series of abstracts was dedicated to apoptosis and approaches to stimulate tumor cells to enter the apoptotic death pathway. Insight into DNA damage and repair is increasing, as well as measures to circumvent cellular drug resistance. Another subject to mention is the generation of dendritic cells for immunotherapy. And last, but not least, presentations concerning the state-of-the-art of microarray technology not only included encouraging data, but also reviewed the problems encountered when using patient's tumor samples for analysis.
Boven
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Vrije Universiteit Medical Centre, Department of Medical Oncology, De Boelelaan 1117, NL-1081 HV, Amsterdam, The Netherlands. e.boven@azvu.nl