title: A prospective, randomized trial of Acticoat versus silver sulfadiazine in the treatment of partial-thickness burns: which method is less painful?
abstract: Despite recent improvements in analgesia, pain control during dressing changes continues to be a major challenge in patients with burns. We investigated two different dressing modalities to compare how much pain the patient experienced during and after the dressing change. Patients with partial-thickness burns that required only topical wound care were assigned randomly to treatment with Acticoat (Smith and Nephew USA, Largo, FL) or silver sulfadiazine (AgSD). The outcome variable was pain during wound care, which was measured using visual analog pain scores. The mean visual analog pain scores for the wounds treated with Acticoat or AgSD wounds were 3.2 and 7.9, respectively (P < .0001; paired Student's t-test). In 41 of the 47 paired pain score observations, the pain in the wound treated with AgSD was perceived as greater than in the wound treated with Acticoat. Burn wound care with Acticoat is less painful than burn wound care with AgSD in patients with selected partial-thickness burns.
authors: DeWitt Daughtry Family Department of Surgery, University of Miami/Jackson Memorial Burn Center, Miami, FL 33101, USA.
authors: Robin Prater
authors: RP
authors: Varas
authors: Terence
authors: T
authors: O'Keeffe
authors: Nicholas
authors: N
authors: Namias
authors: Louis R
authors: LR
authors: Pizano
authors: Olga Delia
authors: OD
authors: Quintana
authors: Marlene
authors: M
authors: Herrero Tellachea
authors: Qammar
authors: Q
authors: Rashid
authors: C Gillon
authors: CG
authors: Ward
mesh_terms: D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects; D001458:Bandages / Q000009:adverse effects; D002056:Burns / Q000150:complications* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis / Q000209:etiology*; D010147:Pain Measurement; D017060:Patient Satisfaction; D011091:Polyesters / Q000008:administration & dosage* / Q000009:adverse effects; D011095:Polyethylenes / Q000008:administration & dosage* / Q000009:adverse effects; D011446:Prospective Studies; D012837:Silver Sulfadiazine / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
chemical_list: C117408:Acticoat; D000891:Anti-Infective Agents, Local; D011091:Polyesters; D011095:Polyethylenes; D012837:Silver Sulfadiazine