Two patients with different features of congenital optic disc anomalies in the two eyes.
OBJECTIVE
Description of two patients, each with different features of congenital optic disc anomalies in the two eyes.


METHODS
Case report


RESULTS
Patient 1, a 3-month-old girl, showed retinochoroidal coloboma involving the optic nerve in the right eye and optic nerve hypoplasia in the left eye. Patient 2, a 5-month-old boy, showed retinal fold extending inferiorly in the right eye and optic disc coloboma in the left eye.


CONCLUSIONS
Since in both cases coloboma was seen in one eye, the optic nerve hypoplasia or retinal fold in the fellow eye of these two patients may have been related to the timing of embryonic fissure opening or closing.
Suzuki
Yumi
Y
Department of Ophthalmology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Kawase
Eriko
E
Nishina
Sachiko
S
Azuma
Noriyuki
N
D002829:Choroid / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology; D003103:Coloboma / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007223:Infant; D008297:Male; D009898:Optic Disk / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D012160:Retina / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology; D014463:Ultrasonography