title: Relative output factor measurements of a 5 mm diameter radiosurgical photon beam using polymer gel dosimetry.
abstract: Besides the fine spatial resolution inherent in polymer gel-magnetic resonance imaging (MRI) dosimetry, the method also features the potential for multiple measurements of varying sensitive volume in a single experiment by integrating results in MRI voxels of finite dimensions (i.e., in plane resolution by slice thickness). This work exploits this feature of polymer gel dosimetry to propose an experimental technique for relative output factor (OF) measurements of small radiosurgical beams. Two gel vials were irradiated with a 5 and 30 mm diameter 6 MV radiosurgery beam and MR scanned with the same slice thickness and three different in plane resolutions. Using this experimental data set, 5 mm OF measurements with the PinPoint ion chamber are simulated by integrating results over a sensitive volume equal to that of the chamber. Results are found in agreement within experimental uncertainties with actual PinPoint measurements verifying the validity of the proposed experimental procedure. The polymer gel data set is subsequently utilized for OF measurements of the 5 mm beam with varying sensitive volume to discuss the magnitude of detector volume averaging effects. Seeking to correct for volume averaging, results are extrapolated to zero sensitive volume yielding a 5 mm OF measurement of (0.66+/-5%). This result compares reasonably with corresponding ionometric and radiographic film measurements of this work and corresponding, limited, data in the literature. Overall, results suggest that polymer gel dosimetry coupled with the proposed experimental procedure helps overcome not only tissue-equivalence and beam perturbation implications but also volume averaging and positioning uncertainties which constitute the main drawback in small radiosurgical beam dosimetry.
authors: Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens, Greece. epappas@cc.uoa.gr
authors: E
authors: E
authors: Pappas
authors: L
authors: L
authors: Petrokokkinos
authors: A
authors: A
authors: Angelopoulos
authors: T G
authors: TG
authors: Maris
authors: M
authors: M
authors: Kozicki
authors: I
authors: I
authors: Dalezios
authors: V
authors: V
authors: Kouloulias
mesh_terms: D002138:Calibration; D005782:Gels / Q000737:chemistry*; D007477:Ions; D008279:Magnetic Resonance Imaging; D010315:Particle Accelerators; D019047:Phantoms, Imaging; D017785:Photons; D011108:Polymers / Q000737:chemistry*; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods*; D016634:Radiosurgery; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy
chemical_list: D005782:Gels; D007477:Ions; D011108:Polymers