title: [Effect of puerarin on the expression of Hsp70 in the rats with cerebral injury induced by acute local ischemia].
abstract: OBJECTIVE
  To study the effect of puerarin on the expression of Hsp (heat shock protein) 70 in the rats with cerebral injury induced by acute local ischemia.
  
  
  METHODS
  Rat model of acute local cerebral ischemia was made by ligating middle cerebral artery. The Hsp70 expression in brain tissue was detected by SP method of immunohistochemistry.
  
  
  RESULTS
  The expression of Hsp70 was significantly higher in puerarintreated rats than those in the rats with cerebral ischemia.
  
  
  CONCLUSIONS
  Puerarin can enhance the level of Hsp70 expression in the rats with cerebral injury induced by acute local ischemia.
authors: People's Hospital of Guangxi Autonomous Region, Nanning 530021, China. php1968@126.com
authors: Hong-ping
authors: HP
authors: Pan
authors: Xiang-lan
authors: XL
authors: Mo
authors: Jia-zhen
authors: JZ
authors: Yang
authors: Lu-li
authors: LL
authors: Li
authors: Zhen-lu
authors: ZL
authors: Huang
authors: Jin
authors: J
authors: Ye
authors: Jin
authors: J
authors: Huang
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D005260:Female; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D020244:Infarction, Middle Cerebral Artery / Q000150:complications; D007529:Isoflavones / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D009474:Neurons / Q000378:metabolism; D018696:Neuroprotective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D029908:Pueraria / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
chemical_list: D018840:HSP70 Heat-Shock Proteins; D007529:Isoflavones; D018696:Neuroprotective Agents; C033607:puerarin