[Bovine leukemia virus as a model for studying human leukemias].
Bovine leukemia virus (BLV) is a retrovirus responsible for lymphoproliferative disorders in ruminants. The comprehensive study of this model system permitted the identification of genetic determinants required for leukemogenesis, the quantification of the dynamic parameters responsible for cell accumulation and the elaboration of novel therapeutic approaches in human.
Willems
L
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Fonds National de la Recherche Scientifique, Biologie cellulaire et moléculaire, Faculté Universitaire des Sciences Agronomiques de Gembloux.
D000818:Animals; D002417:Cattle; D016583:Enzootic Bovine Leukosis / Q000235:genetics; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D001909:Leukemia Virus, Bovine; D008954:Models, Biological