Absolute and relative dose-surface and dose-volume histograms of the bladder: which one is the most representative for the actual treatment?
The purpose of this study was to quantify to what extent relative and absolute bladder dose-volume and dose-surface histograms of the planning CT scan were representative for the actual treatment. We used data of 17 patients, who each received 11 repeat CT scans and a planning CT scan. The repeat CT scans were matched on the planning CT scan by the bony anatomy. Clinical treatment plans were used to evaluate the impact of bladder filling changes on the four histogram types. The impact was quantified by calculating for this patient group the correlation coefficient between the planning histogram and the treatment histogram. We found that the absolute dose-surface histogram was the most representative one for the actual treatment.
Hoogeman
Mischa S
MS
Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Peeters
Stephanie T H
ST
de Bois
Josien
J
Lebesque
Joos V
JV
D001822:Body Burden; D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008297:Male; D008954:Models, Biological; D009928:Organ Specificity; D011471:Prostatic Neoplasms / Q000150:complications / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D011835:Radiation Protection / Q000379:methods*; D011874:Radiometry / Q000379:methods; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods*; D012680:Sensitivity and Specificity; D001743:Urinary Bladder / Q000293:injuries / Q000503:physiopathology* / Q000528:radiation effects*