title: Age as a prognostic factor for complications of major head and neck surgery.
abstract: OBJECTIVE
  To determine if age alone is a prognostic indicator of surgical outcomes for major head and neck procedures.
  
  
  METHODS
  Retrospective cohort study over a 4-year period.
  
  
  METHODS
  Academic referral center, institutional practice, hospitalized care.
  
  
  METHODS
  Included in this study were patients who had undergone ablative, reconstructive, and other major surgical procedures of the head and neck, including neck dissection, laryngectomy, maxillectomy, thyroidectomy with lymphadenectomy, and composite resection of the oral cavity with reconstruction, for both malignant and benign disease.
  
  
  METHODS
  Patient data and intraoperative and postoperative course factors were recorded. Comorbidity was graded using an Adult Comorbidity Evaluation 27 test, Charlson Comorbidity Index, and American Society of Anesthesiology score. Postoperative complications were dichotomized, and multiple logistic regression was used for data analysis.
  
  
  RESULTS
  Medical chart review identified 157 cases. Analysis of data revealed that time under general anesthesia was the only factor consistently related to complications (P<.006), and it was the only factor consistently related to length of stay (P<.001). Analysis of major complications (6% incidence) as an outcome using univariate analysis resulted in a strong positive correlation with both comorbidity indexes: Adult Comorbidity Evaluation 27 (P = .002) and Charlson Comorbidity Index (P = .005). Multiple logistic regression showed no significant relationship between age 70 years or older (20% of patients) and either complications or hospital length of stay.
  
  
  CONCLUSIONS
  Patient's age alone is not a prognostic indicator of surgical outcome for major head and neck procedures. However, comorbidity is an important predictive factor for postoperative complications in any age group. Time under general anesthesia showed a statistically significant relationship with complication rate and hospital length of stay in multivariate analyses. Consequently, prevention of complications should focus on optimizing preoperative comorbid conditions.
authors: State University of New York Downstate Medical Center, Brooklyn, NY, USA. b_marina@excite.com
authors: Marina
authors: M
authors: Boruk
authors: Boris
authors: B
authors: Chernobilsky
authors: Richard M
authors: RM
authors: Rosenfeld
authors: Gady
authors: G
authors: Har-El
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D002648:Child; D005260:Female; D006257:Head / Q000601:surgery*; D006801:Humans; D007825:Laryngectomy; D007902:Length of Stay; D008297:Male; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D009333:Neck / Q000601:surgery*; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D013965:Thyroidectomy; D013997:Time Factors; D016896:Treatment Outcome