Ultrasound promoted synthesis of 5-hydroxy-5-trihalomethyl-4,5-dihydroisoxazoles and beta-enamino trihalomethyl ketones in water.
A convenient method for the preparation of 5-hydroxy-5-trihalo-4,5-dihydroisoxazoles and beta-enamino trihalomethyl ketones, from the reaction of 1,1,1-trihalo-4-alkoxy-3-alken-2-ones with hydroxylamine and anilines, respectively, using water as solvent and under ultrasound irradiation is reported.
Martins
Marcos A P
MA
Departamento de Química, Núcleo de Química de Heterociclos, NUQUIMHE, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil. mmartins@base.ufsm.br
Pereira
Claudio M P
CM
Cunico
Wilson
W
Moura
Sidnei
S
Rosa
Fernanda A
FA
Peres
Rodrigo L
RL
Machado
Pablo
P
Zanatta
Nilo
N
Bonacorso
Helio G
HG