title: Skeletal muscle lipid and its association with insulin resistance: what is the role for exercise?
abstract: Skeletal muscle lipid content has been associated with insulin resistance and type 2 diabetes. However, intramuscular triglycerides can also be a fuel source for healthy muscle during exercise. The balance between storage and use of muscle triglycerides is likely a key to the interaction between dysregulated fat and glucose metabolism by healthy and insulin resistant muscle.
authors: Division of Endocrinology and Metabolism, University of Pittsburgh Department of Medicine, Montefiore Hospital, Pittsburgh, PA 15213, USA. bgood@pitt.edu
authors: Bret H
authors: BH
authors: Goodpaster
authors: Nicholas F
authors: NF
authors: Brown
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D001823:Body Composition; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism / Q000517:prevention & control; D015444:Exercise; D006801:Humans; D007333:Insulin Resistance; D018482:Muscle, Skeletal / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D014280:Triglycerides