title: Mortality and morbidity from moderate to severe traumatic brain injury in Argentina.
abstract: After adopting the Guidelines for the Management of Severe Head Injury, critical care physicians in Argentina reduced the mortality rate of patients with traumatic brain injury (TBI). However, there is no in-hospital or postdischarge rehabilitation services for persons with TBI in Argentina. Thus, severely disabled survivors were being discharged to home without follow-up or long-term care.
  
  
  OBJECTIVE
  The objectives of this project were to establish a structure for conducting research about TBI in Argentina, and to conduct a prospective, observational study of outcomes from TBI in hospitals that had adopted the acute care guidelines. The goal was to document outcomes for people treated in a medical system that does not provide TBI rehabilitation. The focus of this report is mortality and morbidity during the acute care and hospital ward treatment of TBI in Argentina.
  
  
  METHODS
  We established a data-collection system in 5 hospitals in Argentina, using instruments and protocols developed by the NIDRR-funded TBI Model System program. Data-collection intervals were established to be comparable with intervals used in the TBI Model System program. The Argentine team consists of 11 neurocritical care physicians and 1 project manager/translator. All patient evaluation, data collection and entry, quality control, and local administration were conducted by this group.
  
  
  RESULTS
  Over 31 months, 278 patients were entered into the study. Approximately 61% were discharged from acute care directly to home. The in-hospital mortality rate was 31%. Seventy-six percent of expired patients died from secondary complications such as sepsis and pneumonia, and 93% while in the hospital.
  
  
  CONCLUSIONS
  TBI is a major public health concern in Argentina. However, rehabilitation for TBI is not a part of this country's medical system. The greatest proportion of expired patients in the Argentine sample died of secondary complications such as pneumonia or sepsis, which may have been avoided employing basic medical rehabilitation. The next research questions to be addressed in this population should be designed to identify solutions to the immediate need for rehabilitation, including treatment efficacy questions as well as questions about systems for delivering treatments.
authors: Hospital de Emergencias "Dr. Clemente Alvarez", Rosario, Argentina.
authors: Carlos
authors: C
authors: Rondina
authors: Walter
authors: W
authors: Videtta
authors: Gustavo
authors: G
authors: Petroni
authors: Silvia
authors: S
authors: Lujan
authors: Pablo
authors: P
authors: Schoon
authors: Lilian Benito
authors: LB
authors: Mori
authors: Javier
authors: J
authors: Matkovich
authors: Nancy
authors: N
authors: Carney
authors: Randall
authors: R
authors: Chesnut
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D001930:Brain Injuries / Q000150:complications* / Q000401:mortality* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009922:Oregon / Q000453:epidemiology; D011446:Prospective Studies; D016896:Treatment Outcome