Effect of oil loading on microspheres produced by spray drying.
Oil-loaded microspheres were produced by spray drying emulsions consisting of fish oil and modified starch suspensions with different oil loadings. The emulsion stability was assessed by oil droplet size analysis. Microspheres were characterized in terms of size, morphology, yield and microencapsulation efficiency. It was found that an increase in oil loading resulted in emulsions containing larger oil droplets. This corresponded with larger mean microsphere diameters and rounder microspheres. However, high oil loadings produced lower yields and affected microencapsulation efficiencies.
Tan
L H
LH
National University of Singapore, Singapore.
Chan
L W
LW
Heng
P W S
PW
D003890:Desiccation; D004339:Drug Compounding / Q000379:methods*; D004655:Emulsions; D005395:Fish Oils; D010316:Particle Size; D013213:Starch
D004655:Emulsions; D005395:Fish Oils; D013213:Starch