title: [The changes of gastric diseases during the past twenty five years].
abstract: OBJECTIVE
  To study the changes of duodenal ulcer, gastric ulcer, gastric cancer and Helicobacter pylori (Hp) infectious status, according to the clinical data of endoscopy in our hospital during the past 25 years.
  
  
  METHODS
  The patients with duodenal ulcer, gastric ulcer and gastric cancer diagnosed by endoscopy and pathology had been selected, 104 987 general endoscope cases during the period from Jan. 1980 to Dec. 2004. The general cases were divided into 8 age groups as follows: 10-< 20 years old, 20-< 30 years old, 30-< 40 years old, 40-< 50 years old, 50-< 60 years old, 60-< 70 years old, 70-< 80 years old and > or = 80 years old.
  
  
  RESULTS
  The average detected rate of duodenal ulcer, gastric ulcer, and gastric cancer are 13.03%, 4.19% and 1.68% respectively. The detected rate of gastric ulcer was decreased after 1996. The detected rate of duodenal ulcer was decreased after 1999. The gastric cancer detected rate fluctuate between 1.02% and 2.36%. The average ages of duodenal ulcer, gastric ulcer and gastric cancer are 41.8, 50.7 and 59.4 respectively. The tendency of average age shows ascendant. In all patients, the detected rate of Hp showed slightly descendent after 1999.
  
  
  CONCLUSIONS
  The diagnostic age of duodenal ulcer, gastric ulcer and gastric cancer shows ascendant tendency; The detected rates of duodenal ulcer, gastric ulcer show descendent tendency; There is no apparent change in the detected rate of gastric cancer. The Hp detected rate shows descendent tendency slightly.
authors: Department of Gastroenterology, Peking University Third Hospital, Beijing 100083, China. liyazhou@medmail.com.cn
authors: Li-ya
authors: LY
authors: Zhou
authors: Yan
authors: Y
authors: Xue
authors: San-ren
authors: SR
authors: Lin
authors: Ling-mei
authors: LM
authors: Meng
authors: Chuan-feng
authors: CF
authors: Li
authors: Xiu-E
authors: XE
authors: Yan
authors: Na
authors: N
authors: Gao
authors: Kun
authors: K
authors: Wang
authors: Zhuo-yang
authors: ZY
authors: Duan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002681:China / Q000453:epidemiology; D004381:Duodenal Ulcer / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D013276:Stomach Ulcer / Q000175:diagnosis / Q000453:epidemiology*