title: Metastasized angiosarcoma of the spleen in a 2-year-old girl.
abstract: Primary angiosarcoma of the spleen is rare and the prognosis is very poor. The authors present a 2-year-old girl with spontaneous rupture of splenic angiosarcoma. At diagnosis there were liver metastases. After splenectomy she received chemotherapy with ifosfamide, vincristine, and actinomycine D combined with a partial liver resection. She remained in complete remission over 2 years from diagnosis.
authors: Department of Paediatric Surgery, Paediatrics, and Pathology, University Hospital, Maastricht, The Netherlands.
authors: Irma D M
authors: ID
authors: den Hoed
authors: B
authors: B
authors: Granzen
authors: B
authors: B
authors: Granzen
authors: Daniel C
authors: DC
authors: Aronson
authors: Patrick
authors: P
authors: Pauwels
authors: J
authors: J
authors: de Kraker
authors: L W Ernest
authors: LW
authors: van Heurn
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D009362:Neoplasm Metastasis; D011379:Prognosis; D012074:Remission Induction; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy