title: [The importance of hemorheological examinations in experimental limb ischemia-reperfusion injuries].
abstract: Rheological properties of the blood are determined by several factors and if they change it may be diagnostic for many diseases. It is well-known that during ischemia and reperfusion different free-radical liberating pathways are inducted besides the local physical and metabolical changes. These processes may harm red blood cells by increasing their rigidity and impairing their deformability. In ischemia-reperfusion models measurements of erythrocyte deformability is important. Characteristic alterations were observed in both rat and dog hind limb ischemia-reperfusion with vascular clamping on femoral vessels for 1 or 3 hours. Erythrocyte deformability was significantly impaired on the postoperative 1st-3rd days. The acute limb ischemia-reperfusion experimental models seem suitable for further in vivo rheological studies.
authors: Debreceni Egyetem Orvos- és Egészségtudományi Centrum, Sebészeti Mutéttani Tanszék, Debrecen. nemeth@jaguar.unideb.hu
authors: Norbert
authors: N
authors: Németh
authors: Tamás
authors: T
authors: Lesznyák
authors: Miklós
authors: M
authors: Szokoly
authors: Endre
authors: E
authors: Bráth
authors: Katalin
authors: K
authors: Peto
authors: Györgyi
authors: G
authors: Szabó
authors: Adrienn
authors: A
authors: Gulyás
authors: Ferenc
authors: F
authors: Kiss
authors: Sándor
authors: S
authors: Imre
authors: István
authors: I
authors: Furka
authors: Irén
authors: I
authors: Mikó
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004907:Erythrocyte Deformability; D005121:Extremities / Q000098:blood supply*; D018056:Hemorheology; D051381:Rats; D015427:Reperfusion Injury / Q000503:physiopathology*; D013997:Time Factors