[Physical activity and type 2 diabetes].
Muscular exercise promotes glucose utilisation by the skeletal muscle, independently of insulin action, by activating the AMP-activated protein kinase (AMPK). This process is not altered in patients with obesity and/or type 2 diabetes, despite the presence of insulin resistance. Thus, exercise should play a key role in the management of type 2 diabetic patients. Regular physical activity enhances insulin sensitivity, improves glucose control and corrects some cardiovascular risk factors. This paper briefly presents some practical recommendations about physical activity in obese and/or type 2 diabetic patients.
Gautier
J F
JF
Service de Diabétologie et d'Endocrinologie, Hôpital Saint-Louis, INSERM U671, Institut de Recherches biomédicales des Cordeliers, Paris, France. jean-francois.gautier@sls.aphp.fr
D001786:Blood Glucose / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000534:rehabilitation*; D015444:Exercise; D006801:Humans; D007333:Insulin Resistance; D009765:Obesity / Q000150:complications / Q000628:therapy; D012307:Risk Factors
D001786:Blood Glucose