title: Interventional endovascular treatment for Budd-Chiari syndrome with long-term follow-up.
abstract: OBJECTIVE
  To present results of a 9 year followup of percutaneous transluminal angioplasty (PTA) and stents placement in patients with Budd-Chiari Syndrome (BCS) and to evaluate the clinical value and applicability of this approach.
  
  
  METHODS
  44 consecutive patients with BCS (25 male and 19 female; average age, 42.6 years; age range, 19-77 years) were treated with PTA and stents during a 9-year period. The mean duration of symptoms was 46 months. Underlying active malignancy was the cause of occlusion in 5 patients. 3 patients had a history of taking oral contraceptives. The obstructed inferior vena cava (IVC) or hepatic vein (HV) were first dilated by a percutaneous transluminal balloon, and then a self-expanding stent was placed. Clinical patency was defined as absence or improvement of symptoms. Clinical follow-up was supplemented with colour Doppler sonography, CT scan, or both.
  
  
  RESULTS
  Technical success was achieved in 97.2% (35/36) IVC and 83% (10/12) HV PTA and stents. Significantly, the IVC pressure decreased from 2.7 kPa (SD = 0.3) to 1.5 kPa (SD = 0.4) and HV pressure dropped from 2.3 kPa (SD = 0.4) to 1.3 kPa (SD = 0.2). The symptoms and signs disappeared or were relieved after operation in most of the patients. A few serious related complications including one stent migration and one pulmonary emboli occurred and were resolved in time. Patients were followed for a mean of 44 months (range 3-102). Short- and long-term results were satisfactory except for 3 patients (9.4%, 1 IVC, 2 HV) who presented with a restenosis or thrombosis and underwent additional therapy. There were 5 deaths owing to underlying malignant disease 3-17 months after the procedures.
  
  
  CONCLUSIONS
  PTA and stent placements proved a safe and effective treatment in BCS and had a good long-term outcome and should be considered in patients who have symptoms or have no adequate alternative therapy.
authors: Department of Vascular Surgery, the Affiliated Drum Tower Hospital of Nanning University Medical College, China.
authors: Tong
authors: T
authors: Qiao
authors: Chang-jian
authors: CJ
authors: Liu
authors: Chen
authors: C
authors: Liu
authors: Kang
authors: K
authors: Chen
authors: Xue-bin
authors: XB
authors: Zhang
authors: Mao-heng
authors: MH
authors: Zu
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon; D006502:Budd-Chiari Syndrome / Q000601:surgery*; D002681:China; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome