[5C + 1N] annulation: a novel synthetic strategy for functionalized 2,3-dihydro-4-pyridones.
A novel and facile route to functionalized mono/bicyclic 2,3-dihydro-4-pyridones has been developed via formal [5C + 1N] annulation of readily available alpha-alkenoyl ketene-(S,S)-acetals with various aliphatic primary amines.
Dong
Dewen
D
Department of Chemistry, Northeast Normal University, Changchun 130024, PR China. dongdw663@nenu.edu.cn
Bi
Xihe
X
Liu
Qun
Q
Cong
Fangdi
F