[Therapeutic strategy in children with Henoch-Schönlein purpura].
Henoch-Schönlein Purpura (HSP) is the most frequent childhood primary immune vasculitis which affected skin, joints, gastro-intestinal tract and kidney. Renal involvement signs the future disease prognosis. The HSP don't have etiologic treatment but its immuno-histological aspects, leukocytoclastic vasculitis with immune complexes, imposed the including in the therapeutic equation, immunosuppressive and/or cytotoxic drugs, plasmapheresis, kidney transplant (severe renal deficiency resistant to medical treatment) and surgical treatment (in severe gastro-intestinal complications). Identifications of serum and/or urinary markers for the therapeutic answer contribute to appreciate long prognosis disease and precocious and individualized treatment.
Murgu
Alina
A
Universitatea de Mediciná şi Farmacie Gr.T. Popa Iaşi Facultatea de Medicină, Clinica a II-a Pediatrie.
D002648:Child; D002675:Child, Preschool; D006801:Humans; D011695:IgA Vasculitis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation; D010956:Plasmapheresis
D007166:Immunosuppressive Agents