title: F-statistics of clonal diploids structured in numerous demes.
abstract: Abstract The expected apportionment of genetic diversity in diploid clonal organisms structured in numerous subpopulations is explored. Under the specific assumptions considered, corresponding, for instance, to clonal pathogens infecting a large number of hosts, the co-ancestry between individuals within subpopulations is the only nontrivial quantity. Thus the population structure can be fully described either by F(ST) or F(IS), as F(ST) = -F(IS)/(1 - F(IS)). We show that, for most of the parameter space considered, including simulations where equilibrium is not reached and/or where homoplasy is high, the number of effective migrants is most accurately estimated as Nm = -(1 + F(IS))/4F(IS). We further propose a criterion to test for the absence of cryptic sexual reproduction based on the F-statistics F(IS) and F(ST), which is applied to three previously published empirical data sets.
authors: Génétique et Evolution des Maladies Infectieuses, Equipe Evolution des Systèmes Symbiotiques, BP 64501, 34394 Montpellier cedex 5, France. demeeus@mpl.ird.fr
authors: Thierry
authors: T
authors: De Meeûs
authors: François
authors: F
authors: Balloux
mesh_terms: D003198:Computer Simulation; D014644:Genetic Variation; D005828:Genetics, Population; D008957:Models, Genetic; D012098:Reproduction / Q000235:genetics*