title: Ethnic differences in acetylcholinesterase inhibitor use for Alzheimer disease.
abstract: Acetylcholinesterase inhibitors (AChIs) have been demonstrated to improve Alzheimer disease symptoms. Whether the use of AChIs varies by ethnicity is unknown. More than 2500 ethnically diverse patients (6% African American, 14% Latino, and 7% Asian patients) from the Alzheimer's Disease Research Centers in California were studied. Compared with white patients with AD, minority patients had 40% lower odds of AChI use (odds ratio 0.6, 95% confidence interval: 0.5 to 0.7).
authors: Division of Geriatrics, Department of Medicine, University of California, San Francisco, CA, USA. kala@itsa.ucsf.edu
authors: Kala M
authors: KM
authors: Mehta
authors: Maggie
authors: M
authors: Yin
authors: Cynthia
authors: C
authors: Resendez
authors: Kristine
authors: K
authors: Yaffe
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000110:Acetylcholinesterase / Q000378:metabolism; D001741:Black or African American / Q000235:genetics; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000208:ethnology* / Q000235:genetics; D044466:Asian People / Q000235:genetics; D001921:Brain / Q000187:drug effects* / Q000201:enzymology / Q000503:physiopathology; D001923:Brain Chemistry / Q000235:genetics*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D006630:Hispanic or Latino / Q000235:genetics; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D044465:White People / Q000235:genetics
chemical_list: D002800:Cholinesterase Inhibitors; D000110:Acetylcholinesterase; D000109:Acetylcholine