[Clinical pharmacology of analgesics: outlook and risks].
Despite that many drugs are available for pain treatment, many patients are still suffering because of wrong choice or wrong use of analgesics. Both are determined by the degree and the nature of pain to be treated. Non-opioid drugs, especially COX-2-inhibitors are extensively evaluated. If treatment with these drugs is not sufficient, opioids have to be used. Their efficiency is outstanding and their side effects are appropriate. However, doctors and nurses are still reluctant to use opioids because of overestimation of respiratory depression and addiction.
Beubler
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Institut für experimentelle und klinische Pharmakologie, Universität Graz, Osterreich. eckhard.beubler@meduni-graz.at
D000700:Analgesics / Q000009:adverse effects* / Q000145:classification / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects / Q000145:classification / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000145:classification / Q000627:therapeutic use; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000639:trends; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid