title: Ultrasonographic assessment of gastric motility in diabetic gastroparesis before and after attaining glycemic control.
abstract: BACKGROUND
  Glycemic control is important for maintaining gastric motility in diabetic patients, but gastric motility has not yet been studied ultrasonographically in relation to glycemic control.
  
  
  METHODS
  We made such observations before and after establishing glycemic control in diabetic patients with gastroparesis. We studied 30 diabetic patients with upper abdominal digestive symptoms who were hospitalized for correction of poor blood sugar control and who underwent upper digestive tract endoscopy to rule out structural causes such as gastric/duodenal lesions. Gastric motility was evaluated by transabdominal ultrasonography, using a test meal, before and after attainment of glycemic control (within 3 days after admission and 3 days before discharge). Also, upper abdominal digestive symptoms present on admission and at discharge were compared.
  
  
  RESULTS
  After glycemic control was established, contractions of the antral region were more frequent than before the attainment of control (8.93 +/- 1.17/3 min vs 7.63 +/- 2.22/3 min, respectively; P < 0.001). Glycemic control also significantly improved gastric emptying (before glycemic control, 49.2 +/- 14.8%; after, 67.1 +/- 11.5%; P < 0.001). This was also true for the motility index, concerning antral gastric contractility (before control, 2.97 +/- 1.57; after, 3.75 +/- 1.09; P < 0.05). Upper abdominal symptom scores were also significantly lower after attainment of control than before (0.47 +/- 0.78 vs 3.17 +/- 2.00, respectively; P < 0.001).
  
  
  CONCLUSIONS
  These findings suggest that attaining glycemic control improves gastric motility and attainments upper abdominal symptoms in diabetic patients with gastroparesis.
authors: The University of Tokushima Graduate School, Institute of Health Biosciences, Department of Digestive and Cardiovascular Medicine, Tokushima, Japan.
authors: Masahiro
authors: M
authors: Sogabe
authors: Toshiya
authors: T
authors: Okahisa
authors: Koji
authors: K
authors: Tsujigami
authors: Yoshio
authors: Y
authors: Okita
authors: Hiroshige
authors: H
authors: Hayashi
authors: Toshikatsu
authors: T
authors: Taniki
authors: Hiroshi
authors: H
authors: Hukuno
authors: Masahiko
authors: M
authors: Nakasono
authors: Naoki
authors: N
authors: Muguruma
authors: Seisuke
authors: S
authors: Okamura
authors: Susumu
authors: S
authors: Ito
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D005746:Gastric Emptying / Q000502:physiology*; D018589:Gastroparesis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D014463:Ultrasonography
chemical_list: D001786:Blood Glucose