Women's preferences for misoprostol in case of early pregnancy failure.
OBJECTIVE
The aim of this study was to assess the preference of women with early pregnancy failure for treatment with misoprostol as compared to curettage.


METHODS
Women with early pregnancy failure were interviewed and asked whether they were motivated to trade a non-invasive but potentially less effective treatment with misoprostol at the virtually 100% guarantee of complete evacuation after curettage. All women had a structured interview, in which they were informed about both treatment options. The women were asked for a treatment preference in case the complete evacuation rate after misoprostol was set at 100%. In case the women preferred misoprostol, the complete evacuation rate was subsequently decreased to 10% using steps of 5%.


RESULTS
The study group consisted of 64 women with early pregnancy failure. Seven women (11%) did not opt for misoprostol at all, because of fear of pain or bleeding using misoprostol. Fifty percent of the women would prefer misoprostol if its complete evacuation rate exceeds 65%.


CONCLUSIONS
A majority of women would prefer misoprostol over curettage if its complete evacuation rate exceeds 65%.
Graziosi
Giuseppe C
GC
Department of Obstetrics and Gynecology, St. Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands. p.graziosi@Antonius.net
Bruinse
Hein W
HW
Reuwer
Paul J
PJ
Mol
Ben W
BW
D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000328:Adult; D003475:Curettage; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D016595:Misoprostol / Q000008:administration & dosage / Q000627:therapeutic use*; D017060:Patient Satisfaction; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000601:surgery*; D012044:Regression Analysis
D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol