title: Health-related quality of life predicts mortality in older but not younger patients following cardiac surgery.
abstract: The investigators assessed preoperative health-related quality of life as a predictor of 6-month mortality after cardiac surgery in older (65 years of age and older) vs. younger patients. Multivariable regression, stratified by age groups, was used to compare the association between preoperative Physical Component Summary and Mental Component Summary scores from the Short Form-36 health status survey and mortality. In multivariable analyses of older patients, lower preoperative Physical Component Summary (odds ratio, 1.54; 95% confidence interval, 1.19-2.00; p=0.01) and Mental Component Summary (odds ratio, 1.26; 95% confidence interval, 1.06-1.49; p=0.03) scores were independently associated with mortality. In contrast, neither Physical Component Summary (p=0.82) nor Mental Component Summary (p=0.79) scores were associated with mortality in the younger subgroup. This study demonstrated that preoperative health status is an independent predictor of mortality following cardiac surgery in older but not younger patients. Preoperative patient self-report of health status may be particularly useful in refining risk stratification and informing decision-making before and following cardiac surgery in older patients.
authors: Cardiology and Cardiovascular Outcomes Research, Denver VA Medical Center, Denver, CO 80220, USA. michael.ho@uchsc.edu
authors: P Michael
authors: PM
authors: Ho
authors: Frederick A
authors: FA
authors: Masoudi
authors: Pamela N
authors: PN
authors: Peterson
authors: A Laurie
authors: AL
authors: Shroyer
authors: Martin
authors: M
authors: McCarthy
authors: Frederick L
authors: FL
authors: Grover
authors: Karl E
authors: KE
authors: Hammermeister
authors: John S
authors: JS
authors: Rumsfeld
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D006348:Cardiac Surgical Procedures / Q000401:mortality* / Q000706:statistics & numerical data*; D003657:Decision Making; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017063:Outcome Assessment, Health Care; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires