title: Human and nonhuman primate lentiviral infection and autoimmunity.
abstract: The goal of this communication is to summarize the following-the types of autoimmune responses that have been characterized in human HIV-1 infection; the potential mechanisms that were initially thought to be the basis for such autoimmune responses; the prevalence and incidence of conventional autoimmune diseases with HIV-1 infection; the spectrum of autoimmune disorders following the institution of HAART and its associated mechanisms; the role of such autoimmunity in SIV-infected nonhuman primates; and the molecular basis for autoimmune responses, such as the role of exosomes in lentiviral disease.
authors: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors: Nattawat
authors: N
authors: Onlamoon
authors: Kovit
authors: K
authors: Pattanapanyasat
authors: Aftab A
authors: AA
authors: Ansari
mesh_terms: D000818:Animals; D015551:Autoimmunity; D015658:HIV Infections; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008253:Macaca mulatta; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology*; D015302:Simian Immunodeficiency Virus / Q000276:immunology*