[Oxygen saturation in blood during bronchial histamine challenge].
The aim of the study was to evaluate whether significant bronchial constriction which is consequence of histamine administration during the bronchial challenge is accompanied by drop in oxygen saturation in blood (SaO2). A practical aim was to answer the question whether monitoring of saturation by pulsoximetry during the bronchial challenge could improve its method. A study was performed in a group of 25 females and males with non-specific bronchial hyperreactivity. Results of this study revealed a statistically significant association between drop in FEV1 caused by administration of histamine and drop in oxygen saturation, and no association between drop in MEF50 and drop in SaO2. Drop in saturation in blood was not high which does not justify supplementary using of pulsoximetry during the bronchial challenge test.
Złotkowska
Renata
R
Zakład Epidemiologii, Instytut Medycyny Pracy i Zdrowia Srodowiskowego w Sosnowcu.
D000328:Adult; D001985:Bronchial Provocation Tests / Q000379:methods; D016084:Bronchoconstriction / Q000187:drug effects*; D016085:Bronchoconstrictor Agents; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006632:Histamine; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*
D016085:Bronchoconstrictor Agents; D006632:Histamine; D010100:Oxygen