Case reports: mitozantrone-induced onycholysis associated with subungual abscesses, paronychia, and pyogenic granuloma.
Chemotherapeutic agents may induce a wide variety of adverse mucocutaneous effects, including nail changes. We present a case of atypical onycholysis, associated with subungual abscess formation, paronychia and pyogenic granuloma resulting from the use of mitozantrone, an antineoplastic cytotoxic agent, in the treatment of metastatic prostate cancer.
Freiman
Anatoli
A
Division of Dermatology, McGill University, Montreal, Canada. anatoli.freiman@sympatico.ca
Bouganim
Nathaniel
N
O'Brien
Elizabeth A
EA
D000038:Abscess / Q000139:chemically induced* / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D017789:Granuloma, Pyogenic / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008297:Male; D008942:Mitoxantrone / Q000009:adverse effects*; D009260:Nail Diseases / Q000139:chemically induced* / Q000473:pathology; D009262:Nails / Q000473:pathology; D010304:Paronychia / Q000139:chemically induced* / Q000473:pathology
D008942:Mitoxantrone