title: A case of Riedel's thyroiditis treated with tamoxifen: another successful outcome.
abstract: OBJECTIVE
  To report a case of Riedel's thyroiditis, which was successfully treated with tamoxifen.
  
  
  METHODS
  We present the clinical, laboratory, and imaging findings and describe the clinical course of a patient with Riedel's thyroiditis.
  
  
  RESULTS
  A 40-year-old woman presented with hypothyroidism and a large goiter, which was unresponsive to hormone replacement therapy. Magnetic resonance imaging confirmed the presence of an enlarged thyroid gland, more pronounced on the right than on the left. The patient had progressive discomfort attributable to compressive symptoms in the neck. Surgical exploration of the neck disclosed a hard, immobile thyroid mass, which could not be resected because of adherence to surrounding structures. Biopsy of the thyroid and of the muscles of the neck revealed Riedel's thyroiditis. Treatment with tamoxifen, in a dosage of 20 mg twice a day for more than 1(1/2) years, completely resolved the neck mass (substantiated by follow-up magnetic resonance imaging) and relieved the signs and symptoms of compression of the neck.
  
  
  CONCLUSIONS
  Tamoxifen treatment is effective in resolving the mass and compression in Riedel's thyroiditis.
authors: Northeastern Ohio Universities College of Medicine, Rootstown, USA.
authors: Yiechul J
authors: YJ
authors: Jung
authors: Carl R
authors: CR
authors: Schaub
authors: Ronald
authors: R
authors: Rhodes
authors: Frank A
authors: FA
authors: Rich
authors: Stephen J
authors: SJ
authors: Muehlenbein
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D005260:Female; D006042:Goiter / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D013629:Tamoxifen / Q000008:administration & dosage*; D013966:Thyroiditis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen