Gender- and age-related differences in treatment and control of cardiovascular risk factors among high-risk patients with angina.
Dyslipidemic, hypertensive patients (N = 48,863) were stratified by gender, age, and angina (n = 2502) vs. nonangina (n = 46,358) status. Comparing 95% confidence intervals yielded significant differences in treatment and cardiovascular risk factor control between subgroups. More men than women had low-density lipoprotein cholesterol (LDL-C) <100 mg/dL (angina, 43.94-43.96 vs. 34.42-34.50; nonangina, 32.43-32.43 vs. 17.25-17.25) and 100-129 mg/dL (angina, 32.12-32.14 vs. 35.10-35.18; nonangina, 53.86-53.86 vs. 32.44-32.44). More women than men had LDL-C > or = 130 mg/dL (angina, 27.68-27.72 vs. 23.91-23.93; nonangina, 38.70-38.70 vs. 35.38-35.39). Women were less likely than men to receive statins (angina, 69.95-69.99 vs. 82.11-82.13; nonangina, 59.80-59.80 vs. 63.72-63.72), any antilipidemic medication at all (angina, 25.93-25.97 vs. 13.48-13.48; nonangina, 36.73-36.73 vs. 30.73-30.73), or to have current cholesterol measurements (angina, 56.82-56.88 vs. 34.54-34.56; nonangina, 45.77-45.77 vs. 39.75-39.75). Primary care providers treat high-risk patients relatively aggressively; however, opportunities to forestall cardiovascular disease may be missed in hypertensive, dyslipidemic women whose LDL-C is often not measured and controlled.
Hendrix
Katherine H
KH
Department of Medicine, Hypertension Section, Medical University of South Carolina, Charleston, 29425, USA. hendrikh@musc.edu
Mayhan
Susan
S
Egan
Brent M
BM
D000367:Age Factors; D000368:Aged; D000787:Angina Pectoris / Q000150:complications* / Q000188:drug therapy / Q000517:prevention & control; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D050171:Dyslipidemias / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors
D000959:Antihypertensive Agents; D000960:Hypolipidemic Agents