Proteins and polymers.
Proteins, chain molecules of amino acids, behave in ways which are similar to each other yet quite distinct from standard compact polymers. We demonstrate that the Flory theorem, derived for polymer melts, holds for compact protein native state structures and is not incompatible with the existence of structured building blocks such as alpha helices and beta strands. We present a discussion on how the notion of the thickness of a polymer chain, besides being useful in describing a chain molecule in the continuum limit, plays a vital role in interpolating between conventional polymer physics and the phase of matter associated with protein structures.
Banavar
Jayanth R
JR
Department of Physics, 104 Davey Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802, USA. banavar@psu.edu
Hoang
Trinh Xuan
TX
Maritan
Amos
A
D000465:Algorithms; D003198:Computer Simulation; D008956:Models, Chemical; D008958:Models, Molecular; D008968:Molecular Conformation; D044367:Phase Transition; D011108:Polymers / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry* / Q000648:ultrastructure*
D011108:Polymers; D011506:Proteins