Long-term survival of Parkinson's disease: a population-based study.
In a set of a population- based study, long-term survival of 59 prevalent PD patients was compared with that of individuals free of neurological diseases matched 1:2 by sex and age of enrolment. PD individuals, compared with reference subjects, showed a two-fold increased risk of death (OR 2.1; 95 % CI 1.4, 3.1). Among causes of death, pneumonia and cachexia were significantly more frequent among PD patients than among individuals free of neurological diseases. We confirmed in a long-term follow-up study an increased mortality among PD individuals compared with that of the general population.
D'Amelio
M
M
Dipartimento di Neurologia, Oftalmologia Otorinolaringoiatria e Psichiatria, Università Degli Studi di Palermo, Via Gaetano La Loggia 1, 90129, Palermo, Italy.
Ragonese
P
P
Morgante
L
L
Reggio
A
A
Callari
G
G
Salemi
G
G
Savettieri
G
G
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D018672:Community Health Planning; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000453:epidemiology* / Q000401:mortality*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012306:Risk; D012307:Risk Factors; D012737:Sex Factors; D016019:Survival Analysis; D015996:Survival Rate