title: Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae).
abstract: Products made from Herba Santa (Eriodictyon californicum (H. & A.) Torr.) have been used as bitter remedies for some pharmaceutical applications for many years, but they are actually too aromatic to be useful for many food or pharmaceutical applications. In sensory studies flavanones homoeriodictyol (1), its sodium salt (1-Na), sterubin (2), and eriodictyol (4) could significantly decrease the bitter taste of caffeine without exhibiting intrinsic strong flavors or taste characteristics. Further investigations on 1-Na elicited a broad masking activity between 10 and 40% toward different chemical classes of bitter molecules (e.g. salicin, amarogentin, paracetamol, quinine) but not toward bitter linoleic acid emulsions. For caffeine and amarogentin, dose-response studies were performed; the masking activity toward bitter taste for both compounds reached a plateau at higher concentrations of 1-Na. Due to these facts, homoeriodictyol sodium salt (1-Na) seems to be a very interesting new taste modifier for food applications and pharmaceuticals.
authors: Research and Development, Symrise GmbH & Company, KG, P.O. Box 1253, 37601 Holzminden, Germany. jakob.ley@symrise.com
authors: Jakob P
authors: JP
authors: Ley
authors: Gerhard
authors: G
authors: Krammer
authors: Gerald
authors: G
authors: Reinders
authors: Ian L
authors: IL
authors: Gatfield
authors: Heinz-Jürgen
authors: HJ
authors: Bertram
mesh_terms: D031322:Eriodictyon / Q000737:chemistry*; D044950:Flavanones / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology*; D047309:Flavones / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology; D004364:Pharmaceutical Preparations; D013649:Taste / Q000187:drug effects*
chemical_list: D044950:Flavanones; D047309:Flavones; D004364:Pharmaceutical Preparations; C503231:homoeriodictyol