A preliminary study of the patterns of Sin Nombre viral infection and shedding in naturally infected deer mice (Peromyscus maniculatus).
Deer mice (Peromyscus maniculatus) were trapped in southern Manitoba, Canada and tested for evidence of Sin Nombre virus infection. Viral genome was amplified from tissues as well as saliva/oropharyngeal fluid, and urine samples were collected from seropositive animals. Detection of viral RNA in tissue samples and excreta/secreta from mice suggest that differences may exist between naturally infected rodents with respect to viral shedding.
Safronetz
David
D
Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.
Lindsay
Robbin
R
Dibernardo
Antonia
A
Hjelle
Brian
B
Xiao
Ruobing
R
Artsob
Harvey
H
Drebot
Michael A
MA
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D005784:Gene Amplification; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D008297:Male; D008350:Manitoba / Q000453:epidemiology; D009960:Oropharynx / Q000821:virology; D010542:Peromyscus / Q000821:virology*; D012367:RNA, Viral / Q000032:analysis / Q000097:blood / Q000652:urine; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D012376:Rodent Diseases / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D029261:Sin Nombre virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D017201:Virus Shedding
D000914:Antibodies, Viral; D012367:RNA, Viral