title: Synthesis of sterically hindered peptide analogs using diphenyl phosphite as the coupling reagent.
abstract: Some model sterically hindered peptide analogs were synthesized with various yields using diphenyl phosphite as the coupling reagent under mild conditions. The experimental procedure is straightforward and the products are easily isolated. This method may be convenient and efficient for the synthesis of hindered peptides.
authors: Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, PR China.
authors: Ting
authors: T
authors: Yang
authors: Changxue
authors: C
authors: Lin
authors: Hua
authors: H
authors: Fu
authors: Yuyang
authors: Y
authors: Jiang
authors: Yufen
authors: Y
authors: Zhao
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D063065:Organophosphonates; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D007202:Indicators and Reagents; D063065:Organophosphonates; D010455:Peptides; C507805:diphenyl phosphite