title: [Interest of lung scintigraphy for the follow-up of cystic fibrosis (CF) and other chronic obstructive pulmonary disease (COPD). Two case reports in children].
abstract: BACKGROUND
  Lung scintigraphy provides a regional, functional test of pulmonary ventilation and perfusion. It allows an early detection of pulmonary damage or dysfonction, in particular in cystic fibrosis (CF) and other chronic obstructive pulmonary disease (COPD) in childhood.
  
  
  METHODS
  We report two cases in children suffering from CF and COPD (of undefined aetiology), who had a major localized ventilation disorder. They have been detected by lung scintigraphy before the development of clinical or radiological symptoms. An obstructive bronchial cast in the corresponding lobar bronchus was then revealed and withdrawn by bronchial fiberscopy.
  
  
  CONCLUSIONS
  Lung scintigraphy allows early detection of local pulmonary abnormalities, sometimes undetectable with a chest X-ray or even with a chest tomodensitometry. It can reveal bronchial obstructive plugs, avoiding thus the development of bronchectasies thanks to a quick suitable treatment.
authors: Service de pneumologie pédiatrique et allergologique, Assistance-publique-Hôpitaux de Paris, CHU Armand-Trousseau, 75012 Paris, France. emeric.goudard@wanadoo.fr
authors: E
authors: E
authors: Goudard
authors: G
authors: G
authors: Fauveau-Robine
authors: A
authors: A
authors: Grimfeld
mesh_terms: D003550:Cystic Fibrosis / Q000150:complications / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012120:Respiration Disorders / Q000209:etiology; D012129:Respiratory Function Tests