An information-driven approach to pharmacogenomics.
Effective information management of the pharmacogenomics discipline presents many unique challenges. Genetic and genomic data generated via high-throughput methods need to be integrated with phenotypic data which are defined at multiscale levels, ranging from the molecular to the clinical level. Repositories storing these data are distributed and vary in terms of syntax and semantics which result in issues concerning data exchange and integration. The application of the emerging semantic web offers a promising solution to these interoperability issues.
Vyas
Hiten
H
Loughborough University, Health Informatics Research Group,Research School of Informatics, LE11 3TU, UK.
Summers
Ron
R
D000818:Animals; D019295:Computational Biology; D003195:Computer Communication Networks; D003628:Database Management Systems; D030541:Databases, Genetic; D023281:Genomics; D006801:Humans; D019451:Information Management; D016247:Information Storage and Retrieval; D020407:Internet; D010597:Pharmacogenetics; D018511:Systems Integration