title: Estimated dietary exposure to principal food mycotoxins from the first French Total Diet Study.
abstract: This study reports estimates on dietary exposure from the first French Total Diet Study (FTDS) and compares these estimates with both existing tolerable daily intakes for these toxins and the intakes calculated during previous French studies. To estimate the dietary exposure of the French population to the principal mycotoxins in the French diet (as consumed), 456 composite samples were prepared from 2280 individual samples and analysed for aflatoxins, ochratoxin A, trichothecenes, zearalenone, fumonisins and patulin. Average and high percentile intakes were calculated taking account of different eating patterns for adults, children and vegetarians. The results showed that contaminant levels observed in the foods examined 'as consumed' complied fully with current European legislation. However, particular attention needs to be paid to the exposure of specific population groups, such as children and vegans/macrobiotics, who could be exposed to certain mycotoxins in quantities that exceed the tolerable or weekly daily intake levels. This observation is particularly relevant with respect to ochratoxin A, deoxynivalenol and zearalenone. For these mycotoxins, cereals and cereal products were the main contributors to high exposure.
authors: Institut National de Recherche Agronomique, Mét@risk, Unité de méthodologie d'analyse du risque alimentaire, INA-PG, 16 rue Claude Bernard, F-75005 Paris, France. jleblanc@inapg.inra.fr
authors: J-C
authors: JC
authors: Leblanc
authors: A
authors: A
authors: Tard
authors: J-L
authors: JL
authors: Volatier
authors: P
authors: P
authors: Verger
mesh_terms: D000328:Adult; D000348:Aflatoxins / Q000032:analysis; D002648:Child; D004032:Diet; D014676:Diet, Vegetarian; D004781:Environmental Exposure; D005247:Feeding Behavior; D005506:Food Contamination; D005516:Food Microbiology; D005602:France; D037341:Fumonisins / Q000032:analysis; D006801:Humans; D009183:Mycotoxins / Q000008:administration & dosage / Q000032:analysis*; D009793:Ochratoxins / Q000032:analysis; D010365:Patulin / Q000032:analysis; D014255:Trichothecenes / Q000032:analysis; D015025:Zearalenone / Q000032:analysis
chemical_list: D000348:Aflatoxins; D037341:Fumonisins; D009183:Mycotoxins; D009793:Ochratoxins; D014255:Trichothecenes; C025589:ochratoxin A; D015025:Zearalenone; C038405:nivalenol; D010365:Patulin; C007262:deoxynivalenol