One-carbon homologation of N-sulfonylaziridines to allylic amines using dimethylsulfonium methylide.
[reaction: see text]. Regio- and stereodefined allylic N-sulfonylamines are synthesized in high yields and under experimentally straightforward conditions by reaction of N-sulfonylaziridines with excess dimethylsulfonium methylide.
Hodgson
David M
DM
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, UK. david.hodgson@chem.ox.ac.uk
Fleming
Matthew J
MJ
Stanway
Steven J
SJ