title: The first total synthesis of alpha-D-glucopyranosyl-(1-->2)-beta-D-galactopyranosyl-O-pyridinoline, an important hallmark of human joint diseases.
abstract: The first total synthesis of alpha-D-glucopyranosyl-(1-->2)-beta-D-galactopyranosyl-O-pyridinoline using a short "one-pot" assembly of its 1,4,5-trisubstituted 3-hydroxypyridinium ring is reported.
authors: Dipartimento di Chimica, Biochimica e Biotecnologie per la Medicina, Università di Milano, via Saldini 50, I-20133 Milano, Italy. pietro.allevi@unimi.it
authors: Pietro
authors: P
authors: Allevi
authors: Riccardo
authors: R
authors: Cribiù
authors: Elios
authors: E
authors: Giannini
authors: Mario
authors: M
authors: Anastasia
mesh_terms: D004187:Disaccharides / Q000138:chemical synthesis* / Q000378:metabolism; D006801:Humans; D007592:Joint Diseases / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D011725:Pyridines / Q000138:chemical synthesis* / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004187:Disaccharides; D011725:Pyridines; C505635:alpha-D-glucopyranosyl-(1-2)-beta-D-galactopyranosyl-O-pyridinoline