Ipsidirectional impairment of prism adaptation after unilateral lesion of anterior cerebellum.
In a patient with damage of the left cerebellar cortex (SCA territory), the authors tested four combinations of exposure to optical shift (leftward prisms, right hand; rightward prisms, right hand; leftward prisms, left (ataxic) hand; rightward prisms, left (ataxic) hand). He adapted to rightward but not leftward prisms, independent of which hand was used during exposure. This suggests a role of anterior cerebellar cortex in the computation or compensation of ipsidirectional visual error.
Pisella
L
L
Espace et Action, INSERM, Université Claude Bernard Lyon I, Institut Fédératif des Neurosciences de Lyon, Mouvement et Handicap, Lyon, France. pisella@lyon.inserm.fr
Rossetti
Y
Y
Michel
C
C
Rode
G
G
Boisson
D
D
Pélisson
D
D
Tilikete
C
C
D000222:Adaptation, Physiological / Q000502:physiology; D000328:Adult; D001132:Arm / Q000294:innervation / Q000503:physiopathology; D001488:Basilar Artery / Q000473:pathology / Q000503:physiopathology; D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D002531:Cerebellum / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D010468:Perceptual Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology; D013028:Space Perception / Q000502:physiology; D020521:Stroke / Q000175:diagnosis / Q000503:physiopathology*