title: A model of the pacemaking neuron of the respiratory central pattern generator.
abstract: We have developed a model of the mammalian respiratory central pattern generator (rCPG) to mimic the salient characteristics of its constituent medullary neurons. This model is designed as a network of Hodgkin-Huxley-type medullary neurons driven by a pacemaking neuron from the pre-Bötzinger complex. Here, we present the results of our model of this pacemaking neuron, based on available voltage clamp data. Implications for the behavior of the rCPG are discussed.
authors: Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Behrang.Amini@uth.tmc.edu
authors: Behrang
authors: B
authors: Amini
authors: Akhil
authors: A
authors: Bidani
authors: Joseph B
authors: JB
authors: Zwischenberger
authors: John W
authors: JW
authors: Clark
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D005246:Feedback / Q000502:physiology; D006801:Humans; D008168:Lung / Q000294:innervation* / Q000502:physiology*; D008526:Medulla Oblongata / Q000502:physiology; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D015656:Respiratory Mechanics / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology