title: Esophagobronchial fistula in a patient with Behçet's disease: report of a case.
abstract: Esophageal involvement in Behçet's disease is generally considered to be very uncommon. So far, six cases of esophageal ulcers associated with perforation, penetration, or fistula in Behçet's disease have been described in the English literature. This report describes esophagobronchial fistula in a patient with intestinal Behçet's disease. A 62-year-old man was transferred to our hospital for peritonitis due to a small intestinal perforation after an appendectomy. At the age of 14 years he had had recurrent oral ulcers. Ulcerations of the ileum and epididymitis were found, and a pathological examination revealed nonspecific inflammation. Furthermore, an esophageal ulcer with esophagobronchial fistula was diagnosed. The fistula required not only endoscopic treatment but also surgical intervention. The patient's clinical features were consistent with the active phase of intestinal Behçet's disease. The symptoms gradually resolved without any treatment. Four years after remission, however, the symptoms recurred with gastrointestinal hemorrhage and polyarthritis. In the ileocolic region, punch-out ulcerations were noted. The clinical history and features led to a diagnosis of Behçet's disease associated with recurrent gastrointestinal ulcerations. Steroid therapy (prednisolone, 20 mg daily) was started, and led to a rapid resolution of the symptoms. The patient is now being followed up as an outpatient while receiving prednisolone (10 mg per day), without complaint of any gastrointestinal symptoms.
authors: Department of Surgery, Osaka General Medical Center, Sumiyoshi-ku, Osaka 558-8558, Japan.
authors: Yoshikazu
authors: Y
authors: Morimoto
authors: Yasuhiro
authors: Y
authors: Tanaka
authors: Toshinori
authors: T
authors: Itoh
authors: Shigetaka
authors: S
authors: Yamamoto
authors: Youjiro
authors: Y
authors: Kurihara
authors: Kazuhiro
authors: K
authors: Nishikawa
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications*; D001983:Bronchial Fistula / Q000209:etiology / Q000628:therapy*; D013505:Digestive System Surgical Procedures / Q000379:methods; D004937:Esophageal Fistula / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D011239:Prednisolone