title: Sweet syndrome (acute febrile neutrophilic dermatosis) associated with pulmonary coccidioidomycosis.
abstract: BACKGROUND
  Sweet syndrome (acute febrile neutrophilic dermatosis) may arise in association with a variety of underlying systemic diseases. Only 1 case of coccidioidomycosis-associated Sweet syndrome has previously been reported.
  
  
  METHODS
  We describe 2 patients who developed Sweet syndrome during the onset of acute pulmonary coccidioidomycosis. Systemic antifungal therapy was given in both cases. Respiratory symptoms and skin lesions resolved within 5 weeks.
  
  
  CONCLUSIONS
  Sweet syndrome may be a presenting feature of coccidioidomycosis. Recognition of the underlying pulmonary infection is important so that inappropriate treatment with systemic corticosteroids can be avoided.
authors: Department of Dermatology, Mayo Clinic, Scottsdale, AZ 85259, USA. dicaudo.david@mayo.edu
authors: David J
authors: DJ
authors: DiCaudo
authors: Karel Jill
authors: KJ
authors: Ortiz
authors: Stephanie J
authors: SJ
authors: Mengden
authors: Katherine K
authors: KK
authors: Lim
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000368:Aged; D001707:Biopsy, Needle; D002990:Clobetasol / Q000627:therapeutic use; D003047:Coccidioidomycosis; D004359:Drug Therapy, Combination; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D018570:Risk Assessment; D012720:Severity of Illness Index; D016463:Sweet Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D015725:Fluconazole; D002990:Clobetasol