Treatment of chromoblastomycosis with terbinafine: a report of four cases.
This report is about four cases of chromoblastomycosis confirmed by direct examination, histopathology and cultures. The duration of disease infection varied from 5 to 12 years. By culture, Cladosporium carrionii was isolated in two cases and Fonsecaea pedrosoi in the other two cases. Terbinafine 0.25 g twice daily for 1 month and 0.25 g once daily for maintenance therapy were given to three patients. Terbinafine 0.25 g once daily was given to one patient. After 4-8 months of therapy, all cases were cured without relapse when followed up for 6 months. The total dosage of terbinafine was 37.5-60 g. No relevant side effects showed during treatment.
Xibao
Z
Z
Guangzhou Institute of Dermatology, Guangzhou, PR of China. lilichangxing@sina.com
Changxing
L
L
Quan
L
L
Yuqing
H
H
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D002862:Chromoblastomycosis / Q000188:drug therapy* / Q000382:microbiology; D002963:Cladosporium; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D000077291:Terbinafine
D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine