[Pancreas transplantation in the management of diabetes].
Pancreas transplantation has now become an established option in the treatment of diabetic complications. It normalizes glucose metabolism, prevents, stabilizes and improves the evolution of diabetes-associated lesions. Improvements in surgical procedure and in immunosuppression have better defined its indications. Combined kidney-pancreas transplantation appears today as the best treatment for the diabetic patient with end stage renal disease. Isolated pancreas transplantation is reserved to non-uremic patients with severe diabetic complications or with hyperlabile glycaemic control and severe impairment of quality of life.
De Roover
A
A
Service de Chirurgie abdominale, endocrine et transplantation, Nutrition et Maladies métaboliques, CHU Sart Tilman, Liège.
Detry
O
O
Coimbra
C
C
Bonvoisin
C
C
Beaujean
M A
MA
Krzesinski
J M
JM
Paquot
N
N
Scheen
A J
AJ
Honoré
P
P
Meurisse
M
M
D003920:Diabetes Mellitus / Q000628:therapy*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation; D016035:Pancreas Transplantation; D018579:Patient Selection; D011788:Quality of Life; D012720:Severity of Illness Index
D007166:Immunosuppressive Agents; D005947:Glucose