The biology and genetics of obesity and obstructive sleep apnea.
This article reviews current knowledge about a genetic approach to the causes and risk factors for sleep apnea. Recent evidence suggests that genetic variability may play a significant causal role in the pathogenesis of obstructive sleep apnea. The data supporting a genetic influence on sleep apnea, and the perioperative management of patients with sleep apnea are examined.
Tung
Avery
A
Department of Anesthesia and Critical Care, University of Chicago, 5841 South Maryland Avenue, MC4028, Chicago, IL 60637, USA. atung@dacc.uchicago.edu
D006801:Humans; D009765:Obesity / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D012307:Risk Factors; D012737:Sex Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000235:genetics* / Q000503:physiopathology