Structural Aspects of Plant Ferredoxin : NADP(+) Oxidoreductases.
Ferredoxin reductase (FNR) is ubiquitous among photosynthetic organisms as the enzyme directly responsible for the generation of NADPH. Structural studies over the last 15 years have generated over 30 crystal structures of wild-type and mutant FNRs that have yielded a great deal of insight into its structure-function relations. These insights are summarized and combined to propose a structurally informed cycle for FNR catalysis in vivo.
Karplus
P Andrew
PA
Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA, karplusp@science.oregonstate.edu.
Faber
H Richard
HR