Acute hypoxia during organogenesis affects cardiac autonomic balance in pregnant rats.
Changes in ECG parameters were studied in pregnant rats exposed to acute hypobaric hypoxia during the period of organogenesis (gestation days 9 to 10). Rats with low, medium, and high tolerance to hypoxia exhibited pronounced autonomic nervous system imbalance, which become apparent as a loss of correlation between various parameters of ECG signals recorded at rest and during exposure to some stress factors existing under normal conditions.
Maslova
M V
MV
Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University. maslova_masha@mail.ru
Graf
A V
AV
Maklakova
A S
AS
Krushinskaya
Ya V
YV
Sokolova
N A
NA
Koshelev
V B
VB
D000818:Animals; D001341:Autonomic Nervous System / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000294:innervation*; D000860:Hypoxia / Q000503:physiopathology*; D038081:Organogenesis; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000503:physiopathology