title: Prevalence and severity of liver disease in patients with b thalassemia major. A single-institution fifteen-year experience.
abstract: During the last years, liver disease has emerged as a major cause of mortality in patients with b thalassemia major (TM). In spite of its clinical relevance, TM-associated liver damage has been insufficiently characterized. We therefore retrospectively analyzed all TM patients of our Department who underwent liver biopsy since 1990.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Perifanis
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Tziomalos
authors.forename: Ioanna
authors.initials: I
authors.lastname: Tsatra
authors.forename: Stavroula
authors.initials: S
authors.lastname: Karyda
authors.forename: Kalliopi
authors.initials: K
authors.lastname: Patsiaoura
authors.forename: Miranda
authors.initials: M
authors.lastname: Athanassiou-Metaxa
mesh_terms: D005091:Exons; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics*; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology / Q000235:genetics / Q000503:physiopathology*; D009154:Mutation; D015995:Prevalence; D015183:Restriction Mapping; D012189:Retrospective Studies; D017086:beta-Thalassemia / Q000150:complications* / Q000235:genetics
chemical_list: D005954:Glucosephosphate Dehydrogenase