A phytochemical study of the quinolizidine alkaloids from Genista tenera by gas chromatography-mass spectrometry.
Gas chromatography coupled with mass spectrometry has been used to analyse the alkaloids present in the aerial parts of Genista tenera. Anagyrine, cytisine, N-formylcytisine, N-methylcytisine and lupanine were the major compounds, the last two alkaloids being known for their hypoglycaemic activity. Dehydrocytisine, 5,6-dehydrolupanine, rhombifoline, aphylline and thermopsine were the minor alkaloids. The characterisation of the constituents was based on comparison of their Kovats retention indexes and electron impact-mass spectrometric data recorded on-line with those of reference compounds and literature data.
Martins
Alice
A
Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Ed. C8, 5 piso, Campo Grande, 1749-016 Lisboa, Portugal.
Wink
Michael
M
Tei
Andreas
A
Brum-Bousquet
Michèle
M
Tillequin
François
F
Rauter
Amélia-Pilar
AP
D000470:Alkaloids / Q000302:isolation & purification*; D007887:Fabaceae / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D007004:Hypoglycemic Agents / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D011174:Portugal; D011807:Quinolizines / Q000302:isolation & purification*
D000470:Alkaloids; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D011807:Quinolizines