Chorea associated with thyroxine replacement therapy.
Chorea is an uncommonly reported manifestation of hyperthyroidism. We report the first description of generalized chorea due to iatrogenic thyrotoxicosis and propose that the movement disorder is due to a direct effect of thyroxine on the basal ganglia rather than being an autoimmune phenomenon.
Isaacs
Jeremy D
JD
Department of Medicine, Hammersmith Hospital, London, UK. j.isaacs@prion.ucl.ac.uk
Rakshi
James
J
Baker
Richard
R
Brooks
David J
DJ
Warrens
Anthony N
AN
D000368:Aged; D002819:Chorea / Q000209:etiology*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000601:surgery; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000009:adverse effects*
D013974:Thyroxine