[Ocular toxicity caused by chloroquine: case report].
To report a case of ocular toxicity due to chloroquine. The best visual acuity was measured in both eyes with the Snellen chart. Slit-lamp examination of anterior segment, refraction, dilated fundus examination, fluorescein angiography and retinography was done in a 53-year-old patient, female, with rheumatoid arthritis. She had used chloroquine during 6 years and had stopped for 1 year when she came to our service. She had best corrected visual acuity of 20/200 and 20/40. Slit-lamp examination showed intraocular lens in right eye and nuclear cataract (1+/4) in the other, and bilateral corneal subepithelial opacity inferior to the visual axis. Fundus examination showed macular area with retinal pigment epithelium atrophy. Fluorescein angiography showed a bull's eye maculopathy. Report of a typical keratopathy and maculopathy caused by chloroquine.
Inada
Eliane Terumi
ET
Faculdade de Medicina, São José do Rio Preto, Brazil. T_inada@ig.com.br
Watanabe
Karina Paula
KP
Tanaka
Sérgio Gustavo
SG
Sakakisbara
Luís Antônio
LA
D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D002738:Chloroquine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000139:chemically induced*; D008875:Middle Aged; D012164:Retinal Diseases / Q000139:chemically induced*; D014792:Visual Acuity / Q000187:drug effects
D018501:Antirheumatic Agents; D002738:Chloroquine