Dye-sensitized photooxygenation of furanosyl furans: synthesis of a new pyridazine C-nucleoside.
The dye-sensitized photooxygenation of furanosyl furans easily affords C- or O-glycosides with cis-alpha,beta-unsaturated 1,4-dioxo aglycones. The reaction, performed on a ribofuranosyl furan, provides a useful new entry to a novel pyridazine C-nucleoside that can be achieved through a simple one-pot procedure.
Cermola
Flavio
F
Dipartimento di Chimica Organica e Biochimica, Università di Napoli Federico II, Complesso Universitario di M. Sant'Angelo, Via Cinthia 4, 80126 Napoli, Italy. cermola@unina.it
Iesce
M Rosaria
MR
Buonerba
Gianluca
G
D004396:Coloring Agents / Q000737:chemistry*; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010777:Photochemistry; D011724:Pyridazines / Q000737:chemistry*
D004396:Coloring Agents; D005663:Furans; D009705:Nucleosides; D011724:Pyridazines; C062482:pyridazine; D010100:Oxygen