title: Fatty degeneration of myocardial cells as a sign of death due to hypothermia versus degenerative deposition of lipofuscin.
abstract: Lipid-deposits in internal organs, e.g. nephrons, are discussed as reliable marker to determine hypothermia as cause of death. While investigations concerning lipid vacuoles in the epithelium of the renal tubules are already published, there is no systematic information available about hypothermia and lipid deposits in cardiomyocytes. Therefore, this retrospective study presents the first results of lipid-stainings of myocardial samples taken by autopsies in hypothermia-cases in comparison to samples from a control group. It was the aim of the study to clarify the conceivable causal relationship between death due to hypothermia and lipid-deposits apart from lipofuscin and fatty degeneration, respectively, in cardiomyocytes.
authors.affiliation: Institute of Legal Medicine, University of Bonn, Stiftsplatz 12, D-53111 Bonn, Germany. johanna.preuss@ukb.uni-bonn.de
authors.forename: J
authors.initials: J
authors.lastname: Preuss
authors.forename: R
authors.initials: R
authors.lastname: Dettmeyer
authors.forename: E
authors.initials: E
authors.lastname: Lignitz
authors.forename: B
authors.initials: B
authors.lastname: Madea
mesh_terms: D000273:Adipose Tissue / Q000473:pathology*; D001344:Autopsy; D016022:Case-Control Studies; D002423:Cause of Death; D049429:Forensic Pathology; D006801:Humans; D007035:Hypothermia / Q000473:pathology*; D008062:Lipofuscin / Q000502:physiology*; D009206:Myocardium / Q000166:cytology / Q000473:pathology*; D032383:Myocytes, Cardiac / Q000473:pathology; D011237:Predictive Value of Tests
chemical_list: D008062:Lipofuscin