Single-amino-acid difference in the sequence of alpha6 subunit dramatically increases the ethanol sensitivity of recombinant GABAA receptors.
Valenzuela
C Fernando
CF
Mameli
Manuel
M
Carta
Mario
M
D000437:Alcoholism / Q000235:genetics*; D000595:Amino Acid Sequence / Q000235:genetics*; D000818:Animals; D002531:Cerebellum / Q000187:drug effects / Q000503:physiopathology; D005838:Genotype; D006801:Humans; D009865:Oocytes; D051381:Rats; D017207:Rats, Sprague-Dawley; D011963:Receptors, GABA-A / Q000235:genetics*; D011994:Recombinant Proteins / Q000235:genetics; D012641:Selection, Genetic; D014981:Xenopus
C546171:GABRA6 protein, human; D011963:Receptors, GABA-A; D011994:Recombinant Proteins