title: Influence of mimic cardiac rate on hydrodynamics of different mechanical prosthetic cardiac valves in vitro.
abstract: OBJECTIVE
  To assess the influence of mimic cardiac rate on hydrodynamics of different mechanical prosthetic cardiac valves.
  
  
  METHODS
  US-made CarboMedics bileaflet valve, China-made Jiuling bileaflet valve and C-L tilting disc valve were tested via a pulsatile flow simulator in the aortic position. Testing conditions were set at mimic cardiac rates of 55 bpm, 75 bpm, 100 bpm with a constant mimic cardiac output of 4 L/min. The mean pressure differences (deltaP), leakage volumes (L(E)V) and closing volumes (C(L)V) across each valve, and effective orifice areas (EOA) were analyzed.
  
  
  RESULTS
  Within physiological range, deltaP, L(E)V, and C(L)V decreased as mimic cardiac rate increased, with a large extent of variance. EOA increased along with an increase in mimic cardiac rate. It was a different response in terms of cardiac rate alteration for different types of mechanical prosthetic cardiac valves.
  
  
  CONCLUSIONS
  Mimic cardiac rate change affects hydrodynamics of mechanical prosthetic cardiac valves. Within physiological range, the hydrodynamic of prosthetic bileaflet valve is better than that of tilting disc valve.
authors.affiliation: Department of Thoracic & Cardiovascular Surgery, Second Affiliated Hospital, Shanxi Medical University, Taiyuan. cypcardio@163.com
authors.forename: Yin-ping
authors.initials: YP
authors.lastname: Chu
authors.forename: Jin-lian
authors.initials: JL
authors.lastname: Cheng
authors.forename: Ru-kun
authors.initials: RK
authors.lastname: Chen
authors.forename: Yu-bo
authors.initials: YB
authors.lastname: Fan
authors.forename: Fang
authors.initials: F
authors.lastname: Pu
mesh_terms: D001696:Biomechanical Phenomena; D002302:Cardiac Output; D002306:Cardiac Volume; D006339:Heart Rate; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D066298:In Vitro Techniques; D011474:Prosthesis Design; D011673:Pulsatile Flow