title: DNA quantification as prognostic factor in a case of acinar cell carcinoma of the parotid gland, diagnosed by FNA.
abstract: Hereby we present a case of a 43-years-old male who complained of a three years history preauricular painful mass. Fine needle aspiration cytology was performed, diagnosing of compatible with acinar cell carcinoma, thus DNA quantification by image cytometry was carried out. Biological parameters studied (ploidy, S-phase, 5-c exceeding rate) showed that it is a low grade of malignancy lesion. Total parotidectomy conservative of facial nerve was recommended, without regional lymphadenectomy. Patient remains, one year later, asymptomatic and free of disease.
authors.affiliation: Departamento de Anatomía e Histología, Universidad de Zaragoza, Instituto Aragonés de Ciencias de la Salud. javierazua@hotmail.com
authors.forename: Javier
authors.initials: J
authors.lastname: Azúa-Romeo
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Sánchez-Garnica
authors.forename: Javier
authors.initials: J
authors.lastname: Azúa-Blanco
authors.forename: Mayte
authors.initials: M
authors.lastname: Tovar-Lázaro
mesh_terms: D000328:Adult; D000782:Aneuploidy; D044963:Biopsy, Fine-Needle; D018267:Carcinoma, Acinar Cell / Q000235:genetics* / Q000473:pathology; D004261:DNA Replication; D004273:DNA, Neoplasm / Q000032:analysis; D006801:Humans; D019044:Image Cytometry; D008297:Male; D009361:Neoplasm Invasiveness; D010307:Parotid Neoplasms / Q000235:genetics* / Q000473:pathology; D011379:Prognosis
chemical_list: D004273:DNA, Neoplasm