title: Neurotransmission: emerging roles of endocannabinoids.
abstract: Postsynaptic release of endocannabinoids can inhibit presynaptic neurotransmitter release on short and long timescales. This retrograde inhibition occurs at both excitatory and inhibitory synapses and may provide a mechanism for synaptic gain control, short-term associative plasticity, reduction of synaptic crosstalk, and metaplasticity.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305, USA.
authors.forename: Anatol C
authors.initials: AC
authors.lastname: Kreitzer
mesh_terms: D001921:Brain / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism; D063385:Cannabinoid Receptor Modulators / Q000378:metabolism*; D063388:Endocannabinoids; D006801:Humans; D009433:Neural Inhibition / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D013569:Synapses / Q000378:metabolism / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
chemical_list: D063385:Cannabinoid Receptor Modulators; D063388:Endocannabinoids; D018377:Neurotransmitter Agents; D002118:Calcium