Effect of hip hemiarthroplasty on articular cartilage and bone in a canine model.
The purpose of this study was to determine if acetabular articular cartilage damage occurs in the presence or absence of changes in subchondral plate thickness or porosity and trabecular bone architecture after hip hemiarthroplasty. Eight canines were sacrificed 6 months after receiving unilateral hemiarthroplasties in which a cobalt chrome alloy femoral head was used. The acetabular cartilage, subchondral plate, and trabecular bone were quantitatively evaluated. Although the articular cartilage in the treated hip showed gross and histologic degenerative changes, there were no differences in the treated and contralateral hips in any of the trabecular bone parameters or subchondral plate thickness. However, the subchondral plate porosity was increased 2.6-fold in the treated hip. Therefore, degradation of cartilage can occur in the absence of thickening of the subchondral plate or alterations in the supporting trabecular bone architecture. These observations provide a better understanding of the role that periarticular bone has in the degenerative process after hemiarthoplasty.
Minihane
Keith P
KP
Department of Orthopedic Surgery, Rush Medical College, Chicago, IL 60612, USA.
Turner
Thomas M
TM
Urban
Robert M
RM
Williams
James M
JM
Thonar
Eugene J-Ma
EJ
Sumner
Dale R
DR
D000077:Acetabulum / Q000000981:diagnostic imaging / Q000648:ultrastructure*; D000818:Animals; D019644:Arthroplasty, Replacement, Hip / Q000379:methods; D001672:Biocompatible Materials; D001861:Bone Regeneration / Q000502:physiology; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000648:ultrastructure*; D002858:Chromium Alloys; D004195:Disease Models, Animal; D004285:Dogs; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D008297:Male; D008855:Microscopy, Electron, Scanning; D016062:Porosity; D011474:Prosthesis Design; D011859:Radiography
D001672:Biocompatible Materials; D002858:Chromium Alloys