Occupational eosinophilic bronchitis without asthma due to chloramine exposure.
A case is discussed of eosinophilic bronchial inflammation without asthma due to chloramine T (CLT) exposure in a nurse. She reported a non-productive chronic cough on contact with CLT during workshifts. She had negative results of skin prick testing to CLT. However, sensitisation to CLT was confirmed by the presence of specific anti-chloramine IgE. Airway responsiveness to histamine was normal before and after CLT challenge. Eosinophil proportion in sputum was increased at 6 and 24 h after CLT challenge.
Krakowiak
Anna M
AM
Department of Occupational Diseases, Nofer Institute of Occupational Medicine, Łódź, Poland. annakrak@imp.lodz.pl
Dudek
Wojtek
W
Ruta
Urszula
U
Palczynski
Cezary
C
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001991:Bronchitis / Q000139:chemically induced* / Q000188:drug therapy; D019819:Budesonide / Q000627:therapeutic use; D002700:Chloramines / Q000633:toxicity*; D002908:Chronic Disease; D003371:Cough / Q000139:chemically induced / Q000188:drug therapy; D004202:Disinfectants / Q000633:toxicity*; D004802:Eosinophilia / Q000139:chemically induced* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D014105:Tosyl Compounds / Q000633:toxicity*
D000893:Anti-Inflammatory Agents; D002700:Chloramines; D004202:Disinfectants; D014105:Tosyl Compounds; C016300:chloramine-T; D019819:Budesonide