Left frontotemporal hyperperfusion in a patient with post-stroke mania.
A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania.
Mimura
Masaru
M
Department of Neuropsychiatry, Showa University School of Medicine, 1-5-8 Hatanodai, Tokyo 142-8666, Japan. mimura@med.showa-u.ac.jp
Nakagome
Kazuyuki
K
Hirashima
Natsuko
N
Ishiwata
Hiroshi
H
Kamijima
Kunitoshi
K
Shinozuka
Akira
A
Matsuda
Hiroshi
H
D000368:Aged; D001714:Bipolar Disorder / Q000209:etiology*; D002560:Cerebrovascular Circulation / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply* / Q000473:pathology / Q000503:physiopathology*; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications* / Q000473:pathology; D013702:Temporal Lobe / Q000098:blood supply* / Q000473:pathology / Q000503:physiopathology*; D015899:Tomography, Emission-Computed, Single-Photon