title: Modified percutaneous ethanol injection in the treatment of viscous cystic thyroid nodules.
abstract: Here we describe a prospective 2-year evaluation of the efficiency of a new procedure of percutaneous ethanol injection (PEI) treatment of viscous thyroid cystic nodules (VTCN). Three patients with VCTN were selected from a group of 22 patients with solitary thyroid cystic nodules. A modified two-stage ethanol injection procedure was planned for these patients. Stage 1 was performed through the injection of a small dose of ethanol into the nodule. The viscosity of the content was reduced within 2 weeks after the injection. In the second stage the nodule was decompressed and an established dose of sterile 95% ethanol was injected. Patients were followed up for 2 years. In all cases a reduction in nodule volume was found. In the following 18 months further reduction was observed, with an average of 91.7%. The effect was stable throughout the follow-up period. No complications were observed. Therefore, our new two-stage PEI procedure appears all efficient alternative approach for the treatment of VCTNs even if further investigations on a larger series are required.
authors.affiliation: Center for Laser Diagnostics and Therapy Chair and Clinic of Internal Diseases and Physical Medicine, Silesian Medical University, Bytom, Poland. wzieleznik@2com.pl
authors.forename: Witold
authors.initials: W
authors.lastname: Zieleźnik
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Kawczyk-Krupka
authors.forename: Marta Peszel
authors.initials: MP
authors.lastname: Barlik
authors.forename: Wojciech
authors.initials: W
authors.lastname: Cebula
authors.forename: Aleksander
authors.initials: A
authors.lastname: Sieroń
mesh_terms: D000328:Adult; D000368:Aged; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012997:Solvents / Q000008:administration & dosage*; D016606:Thyroid Nodule / Q000188:drug therapy*; D016896:Treatment Outcome; D014783:Viscosity
chemical_list: D012997:Solvents; D000431:Ethanol