Study of the surface morphology of a cholesteryl tethering system for lipidic bilayers.
The immobilization of functional molecules embedded in lipidic membranes onto inorganic substrates is of great interest for numerous applications in the fields of biosensors and biomaterials. We report on the preparation and the morphological characterization of a tethering system for lipidic bilayers, which is based on cholesteryl derivatives deposited on hydrophilic surfaces by self-assembling and microcontact printing techniques. The investigation of the structural properties of the realized films by atomic, lateral, and surface potential microscopy allowed us to assess the high quality of the realized cholesteryl layers.
Blasi
L
L
NNL, National Nanotechnology Laboratory of Istituto Nazionale di Fisica della Materia (INFM), c/o Dipartimento di Ingegneria dell'Innovazione, Università di Lecce, via Arnesano, 73100 Lecce, Italy. laura.blasi@unile.it
Pisignano
D
D
Di Benedetto
F
F
Maruccio
G
G
Ciccarella
G
G
Maffei
A
A
Vasapollo
G
G
Cingolani
R
R
Rinaldi
R
R
D002784:Cholesterol / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D020527:Microscopy, Scanning Probe; D013499:Surface Properties
D008051:Lipid Bilayers; D002784:Cholesterol