Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces griseus strain from Antarctica.
A new angucyclinone antibiotic, frigocyclinone, was isolated from Streptomyces griseus strain NTK 97, consisting of a tetrangomycin moiety attached through a C-glycosidic linkage with the aminodeoxysugar ossamine. Frigocyclinone showed antibacterial activities against Gram-positive bacteria.
Bruntner
Christina
C
Mikrobiologisches Institut, Universität Tübingen, au der Morgenstelle 28, D-72076 Tübingen, Germany.
Binder
Tatiana
T
Pathom-aree
Wasu
W
Goodfellow
Michael
M
Bull
Alan T
AT
Potterat
Olivier
O
Puder
Carsten
C
Hörer
Stefan
S
Schmid
Angela
A
Bolek
Walter
W
Wagner
Klaus
K
Mihm
Gerhard
G
Fiedler
Hans-Peter
HP
D000864:Antarctic Regions; D000880:Anthraquinones / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002851:Chromatography, High Pressure Liquid; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D013056:Spectrophotometry, Ultraviolet; D013305:Streptomyces griseus / Q000378:metabolism*
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; C502980:frigocyclinone