Septic knee arthritis after intra-articular hyaluronate injection. Two case reports.
Intraarticular sodium hyaluronate injection to treat osteoarthritis is associated with minor side effects. Infections seem uncommon. We report two cases of septic knee arthritis. One patient was an 80-year-old woman who was admitted for Staphylococcus aureus knee arthritis after several intraarticular injections of sodium hyaluronate and corticosteroids. In the other patient, a 78-year-old woman, Neisseria mucosa knee arthritis occurred after a single sodium hyaluronate injection. Faultless aseptic technique is essential when administering hyaluronate viscosupplementation. Patients should be informed of the risk of septic arthritis.
Albert
Christine
C
Rheumatology Department, Archet 1 Teaching Hospital, CHU de Nice, 151 Rte St Antoine de Ginestière, BP 3079, 06202 Nice cedex 3, France. albert-sabonnadiere.c@chu-nice.fr
Brocq
Olivier
O
Gerard
Delphine
D
Roux
Christian
C
Euller-Ziegler
Liana
L
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D007270:Injections, Intra-Articular; D007719:Knee Joint / Q000187:drug effects / Q000473:pathology; D042807:Neisseria mucosa / Q000302:isolation & purification / Q000502:physiology; D016870:Neisseriaceae Infections / Q000209:etiology* / Q000473:pathology; D020370:Osteoarthritis, Knee / Q000150:complications / Q000188:drug therapy*; D010068:Oxacillin / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000209:etiology* / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000502:physiology
D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D006820:Hyaluronic Acid; D010068:Oxacillin