Relationship between newborn size and mother's blood cadmium levels, Toyama, Japan.
The effect of blood cadmium (Cd), which reflects not only Cd body burden but also recent Cd exposure and communicates with fetal blood in the placenta, on newborn size at birth was investigated. Blood Cd of 55 mothers from Toyama, Japan, at 30-32 gestational weeks was measured using a flameless atomic absorption spectrophotometer. The relationship between blood Cd and newborn size was analyzed after adjustment for gestational age and maternal build. A significant inverse correlation was found between infant height and maternal blood Cd. After adjustment for gestational age and maternal weight at 30-32 gestational weeks, the significant inverse relationship between maternal blood Cd and infant height was shown using the multiple regression analysis. Newborn size might be influenced by maternal blood Cd levels to which infants may be exposed during gestation.
Nishijo
Muneko
M
Department of Public Health, Kanazawa Medical University, Uchinada, Ishikawa, Japan. ni-koei@kanazawa-med.ac.jp
Tawara
Kenji
K
Honda
Ryumon
R
Nakagawa
Hideaki
H
Tanebe
Kyoko
K
Saito
Shigeru
S
D000328:Adult; D000886:Anthropometry; D001822:Body Burden; D002104:Cadmium / Q000097:blood*; D005260:Female; D005317:Fetal Growth Retardation / Q000139:chemically induced*; D005865:Gestational Age; D006801:Humans; D007230:Infant, Low Birth Weight / Q000097:blood*; D007231:Infant, Newborn; D007564:Japan; D018811:Maternal Exposure / Q000009:adverse effects*; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D011247:Pregnancy; D012307:Risk Factors; D013054:Spectrophotometry, Atomic
D002104:Cadmium