[The clinical and pharmacokinetic features of lymphotropic therapy in patients with new-onset pulmonary tuberculosis].
Regional lymphotropic therapy used in complex treatment of patients with new-onset pulmonary tuberculosis enhances its efficiency. It is well tolerated by patients and easy-to-use. The pharmacokinetic feature of isoniazid during its lymphotropic administration is its shorter elimination half-life, decreased total clearance, and a larger area under the pharmacokinetic curve.
Priakhina
V N
VN
Kolpakov
M A
MA
Kolpakov
A R
AR
Zyrianova
T V
TV
Mokhina
O G
OG
D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D008198:Lymph Nodes / Q000378:metabolism*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents; D007538:Isoniazid