Colon perforation in an adolescent after short-term diclofenac intake.
Chronic intake of non-steroidal anti-inflammatory drugs (NSAIDs) has been reported to cause side-effects distal to the duodenum. These include strictures, diaphragm-like lesions and perforations of the small and large intestines. This is the first case report on colon perforation occurring in an adolescent (16-year-old girl) after short-term diclofenac intake.
Schiffmann
L
L
Department of General, Vascular and Thoracic Surgery, Charite, University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany. leif@gmx.de
Kahrau
S
S
Berger
G
G
Buhr
H J
HJ
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003108:Colonic Diseases / Q000139:chemically induced* / Q000473:pathology; D004008:Diclofenac / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000139:chemically induced* / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac