3D CT protocol in the assessment of the esophageal neoplastic lesions: can it improve TNM staging?
The purpose of this prospective observational study was the evaluation of the usefulness of MPR reconstructions and virtual endoscopy in the study of the esophageal carcinoma. Thirty-nine patients with esophageal cancer proved by means of endoscopy, underwent preoperative TNM staging with dynamic CT of the chest and abdomen with the aid of 3D rendering. Twenty-six patients underwent surgery, and the CT results were compared with histopathologic findings. In staging the T parameter, the CT with 3D reconstructions and virtual endoscopy, showed a sensitivity of 92% and an accuracy of 88%. In staging lymph nodes, the sensitivity in our study was 85%, the specificity 58%, and the accuracy 69%. Our protocol of the study of the esophageal cancer with 3D CT and virtual endoscopy, demonstrated a high concordance with the surgical and pathologic findings. The 3D reconstructed images were very helpful to the surgeons regarding preoperative planning. We performed an observational enquiry, and although this was a small study, it has, however, confirmed that the 3D imaging of the esophagus represents a valuable advantage to conventional imaging. Further studies with a larger number of patients are needed to prove its superiority to traditional CT imaging of the esophagus.
Panebianco
V
V
Department of Radiological Sciences, University of Rome La Sapienza, Viale del Policlinico 155, 00161, Rome, Italy. valeria.panebianco@uniroma1.it
Grazhdani
H
H
Iafrate
F
F
Petroni
M
M
Anzidei
M
M
Laghi
A
A
Passariello
R
R
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D003287:Contrast Media / Q000008:administration & dosage; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D004940:Esophageal Stenosis / Q000473:pathology / Q000601:surgery; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007479:Iopamidol / Q000031:analogs & derivatives; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000379:methods*; D014584:User-Computer Interface
D003287:Contrast Media; C057937:iomeprol; D007479:Iopamidol