Erythropoietin and IL-3 receptor cell surface expression is decreased under conditions that model some aspects of microgravity.
Xu
Kun
K
Laboratory for Cell and Molecular Biology, Division of Hematology and Oncology, Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.
Feldman
Laurie
L
Davis
Kerry L
KL
Sytkowski
Arthur J
AJ
D019149:Bioreactors; D002468:Cell Physiological Phenomena; D002478:Cells, Cultured / Q000187:drug effects; D003470:Culture Media; D004921:Erythropoietin / Q000494:pharmacology*; D006801:Humans; D007457:Iodine Radioisotopes; D011869:Radioligand Assay; D011956:Receptors, Cell Surface / Q000032:analysis*; D017467:Receptors, Erythropoietin; D016185:Receptors, Interleukin-3 / Q000378:metabolism*; D012399:Rotation; D018474:Weightlessness Simulation
D003470:Culture Media; D007457:Iodine Radioisotopes; D011956:Receptors, Cell Surface; D017467:Receptors, Erythropoietin; D016185:Receptors, Interleukin-3; D004921:Erythropoietin