title: [The threatening influenza pandemic: a national store ofoseltamivir is a waste of money].
abstract: In the treatment of confirmed influenza, neuraminidase inhibitors yield only a limited reduction in the duration of disease and are neither efficacious nor cost-effective. Neuraminidase inhibitors would be cost-effective if a deadly influenza virus that is highly sensitive to oseltamivir causes a pandemic soon. If not, then the money invested in establishing a store of oseltamivir is wasted and lost to the health-care sector.
authors.affiliation: Federaal Kenniscentrum voor de Gezondheidszorg (KCE), Residence Palace Ioe verdieping, Wetstraat 155, B-1040 Brussel, België. luc.bonneux@kenniscentrum.fgov.be
authors.forename: L
authors.initials: L
authors.lastname: Bonneux
mesh_terms: D000081:Acetamides / Q000191:economics / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000191:economics / Q000627:therapeutic use*; D004189:Disaster Planning; D004196:Disease Outbreaks / Q000517:prevention & control; D016527:Drug Costs; D024882:Drug Resistance, Viral; D004791:Enzyme Inhibitors / Q000191:economics / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy* / Q000453:epidemiology; D009426:Netherlands / Q000453:epidemiology; D053139:Oseltamivir; D011634:Public Health
chemical_list: D000081:Acetamides; D000998:Antiviral Agents; D004791:Enzyme Inhibitors; D053139:Oseltamivir