Nature and correlates of SF-12 physical and mental quality of life components among low-income HIV adults using an HIV service center.
OBJECTIVE
This study describes health-related quality of life (HRQOL) among low-income HIV adults using an HIV service center, compares participants' scores to US published norms for the general population and persons with chronic conditions, and examines relationships between patient characteristics, nonadherence, and HRQOL.


METHODS
A cross-sectional survey of individuals on antiretroviral therapy was conducted. The Medical Outcomes Study SF-12 was used to assess HRQOL. Medication nonadherence was assessed using the 9-item Morisky Adherence Scale. Data also were collected on social support, CD4 cell count, and time since diagnosis.


RESULTS
Approximately 84% of the 86 participants were male, 50% were white, and 39% were black. The mean +/- SD Physical component summary (PCS-12) score of 41.0 +/- 12.5 and Mental component summary (MCS-12) score of 41.9 +/- 11.0 were lower than US general population norms (p < 0.001). PCS-12 scores were similar to those of patients with other chronic conditions. Respondents reported lower MCS-12 scores than patients with hypertension and diabetes (p < 0.006). Employment and higher social support had positive associations with PCS-12 scores and nonadherence had a negative association with MCS-12 scores (p < 0.05).


CONCLUSIONS
HRQOL in this sample of low-income HIV adults was comparable to other HIV populations. Identifying strategies for increasing social support and medication adherence for economically disadvantaged persons with HIV/ AIDS may improve their HRQOL.
Viswanathan
Hema
H
School of Pharmacy and Pharmacal Sciences, Department of Pharmacy Practice, Purdue University, West Lafayette, IN 47907-2091, USA.
Anderson
Rodney
R
Thomas
Joseph
J
D000293:Adolescent; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology*; D006801:Humans; D007196:Indiana; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011203:Poverty; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires