title: Uveitis in Gaucher disease.
abstract: OBJECTIVE
  Chronic uveitis has been previously reported in a patient with Gaucher's disease and improved with enzyme replacement therapy. This report describes the course of uveitis in two other patients with type I Gaucher's disease.
  
  
  METHODS
  Observational case reports.
  
  
  METHODS
  Review of all patients in a large referral clinic for Gaucher's disease for incidence of uveitis.
  
  
  RESULTS
  Two patients with uveitis among 527 patients (0.4%) were found. Each had a different clinical outcome from the other and from the patient cited in the literature.
  
  
  CONCLUSIONS
  Both patients have mild Gaucher's disease, but one patient has uveitis well controlled for 10 years solely by local corticosteroids, whereas the other has suffered progression of uveitis despite enzyme replacement therapy.
authors.affiliation: Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel. gaucher@szmc.org.il
authors.forename: Altoon
authors.initials: A
authors.lastname: Dweck
authors.forename: Jaacov
authors.initials: J
authors.lastname: Rozenman
authors.forename: Suzy
authors.initials: S
authors.lastname: Ronen
authors.forename: Ari
authors.initials: A
authors.lastname: Zimran
authors.forename: Deborah
authors.initials: D
authors.lastname: Elstein
mesh_terms: D000328:Adult; D005260:Female; D005776:Gaucher Disease / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D005938:Glucocorticoids / Q000627:therapeutic use; D005962:Glucosylceramidase / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D014605:Uveitis / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D005938:Glucocorticoids; D005962:Glucosylceramidase