title: [Diagnostic value of the second prostate biopsies in males of risk. Study stratified by value of PSA].
abstract: OBJECTIVE
  [corrected] To value the diagnostic yield of the second prostate biopsy (BP).
  
  
  METHODS
  To 116 males with BP previous to kindliness surrendered to 2 or more BP for sextants guided with ultrasounds (US). The criteria of inclusion were: BP previous suspicious (PIN), high PSA, TR or suspicious US.
  
  
  RESULTS
  The average time passed between the first and following biopsy was 13 +/- 11 months. 35 malignant and 4 premalignant ones were obtained in the second realized biopsies, which gives a diagnostic global yield of 33.6%. When we stratify for value of PSA, we obtain that with PSA <4 ng/ml the yield was 23%, for PSA 4-10 ng/ml the yield was 32% and for PSA >10 ng/ml of 34.6%.
  
  
  CONCLUSIONS
  The repetition of the serial biopsy of prostate in patients of risk, improves the diagnostic yield and eliminates the false negatives of prostate carcinoma.
authors.affiliation: Fundación Instituto Valenciano de Oncologia, Valencia.
authors.forename: J
authors.initials: J
authors.lastname: Cervera Deval
authors.forename: F J
authors.initials: FJ
authors.lastname: Morales Olaya
authors.forename: J
authors.initials: J
authors.lastname: Jornet Fayos
authors.forename: M
authors.initials: M
authors.lastname: González Añón
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology*; D012307:Risk Factors
chemical_list: D017430:Prostate-Specific Antigen