[The role of serum amyloid A in the early diagnosis of acute coronary syndrome].
The aim of this study was to evaluate diagnostic usefulness of serum amyloid A (SAA) in diagnosis of acute myocardial infarction (AMI) in group of patients with stenocardia. The study was carried out in group of 62 patients admitted to Emergency Unit of 5-th Military Hospital in Krakow. The study group consisted of 24 (38.7%) patients with unstable angina pectoris and 38 (61.3%) with acute myocardial infarction. It was found that SAA concentration significantly increases in patients with AMI: 136.0 +/- 220.6 mg/L versus 7.38 +/- 8.8 mg/L in unstable angina pectoris (p < or = 0.009). Studies of mutual relations between SAA levels and cardiac markers have shown a remarkably positive correlation between SAA and troponin I (r = 0.39; p < or = 0.01) and negative correlation between SAA concentrations and platelet count decrease (r = -0.55; p < or = 0.01).
Cabala
Marcin
M
Szpitalny Oddział Ratunkowy, 5 Wojskowy Szpital Kliniczny z PoliklinikaSP ZOZ, Wrocławska 1-3. marcin10@autocom.pl
Gajdosz
Ryszard
R
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000097:blood* / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis*; D000685:Serum Amyloid A Protein / Q000378:metabolism*
D015415:Biomarkers; D000685:Serum Amyloid A Protein