[Revealing dacryoadenitis inflammation as Wegener's granulomatosis].
BACKGROUND
Wegener's granulomatosis is a necrotizing granulomatous vasculitis characterized by the involvement of the upper airways, lungs and kidneys.


METHODS
A 39-year-old man presented with a 8-month history of proptosis of left eye. He had a history of recuring sinusitis and dyspnea. The diagnosis of Wegener's granulomotosis was confirmed by the nasal biopsy. A complete remission was achieved after treatment with corticosteroids, cyclophosphamide and trimethoprine sulfamethoxazole.


CONCLUSIONS
Wegener's granulomatosis is a multisystemic inflammatory disease of unknown origin. The classic diagnostic triad of this disease is necrotizing granuloma of the upper or lower respiratory tract, vasculitis and nephritis. The disease is usually fatal if untreated. However, early diagnosis and immunosuppressives such as cyclophosphamide can induce long term remission.
Tachfouti
S
S
Service d'Ophtalmologie A, Hôpital des Spécialités, Rabat, Maroc. s_tachfouti@hotmail.com
Boutimzine
N
N
Cherkaoui
O
O
Bencherif
Z
Z
Dahreddine Mohcine
Z
Z
D000328:Adult; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003607:Dacryocystitis / Q000209:etiology*; D004338:Drug Combinations; D005094:Exophthalmos / Q000209:etiology*; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000473:pathology*; D013411:Sulfadiazine / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use; D000096926:Benzenesulfonamides
D003520:Cyclophosphamide; D004338:Drug Combinations; D013411:Sulfadiazine; D014295:Trimethoprim; C024873:sulfadiazine, trimethoprim drug combination; D000096926:Benzenesulfonamides