title: Comparison of eight different digital chest radiography systems: variation in detection of simulated chest disease.
abstract: OBJECTIVE
  In a short period, a variety of technically different digital radiography chest systems have become available for clinical use. Our purpose was to assess the diagnostic performance of eight different digital radiography chest systems for detection of simulated chest disease under clinical conditions.
  
  
  METHODS
  Assessed were four different flat-panel detector systems, two different charge-coupled device systems, one selenium-coated drum, and one storage phosphor system. For each system, 10 chest images of an anthropomorphic chest phantom were obtained. Each image contained one to 12 simulated chest lesions. Eight radiologists performed soft-copy interpretations. Entrance dose was measured and effective dose calculated. A semi-parametric logistic regression model was used for statistical analysis.
  
  
  RESULTS
  Statistically significant differences were found in the diagnostic performance of the eight digital chest systems (p = 0.01). Best performance was observed with the charge-coupled device system with slot-scan technology, yielding a sensitivity of 46% (132 of 288) lesions detected. The performance of three flat-panel detectors and the selenium-drum system was not significantly different from the slot-scan charge-coupled device system. Fewer lesions were detected with the storage phosphor system than with all other digital technologies, with a sensitivity of 34% (99 of 288) lesions detected, slot-scan charge-coupled device system versus storage phosphor system, p < 0.001. The effective dose varied among the digital systems.
  
  
  CONCLUSIONS
  We found differences in diagnostic performance among the eight different digital chest systems. Differences in detection rates are predominantly explained by detector design.
authors.affiliation: Department of Radiology, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands 2333 ZA. l.j.m.kroft@lumc.nl
authors.forename: Lucia J M
authors.initials: LJ
authors.lastname: Kroft
authors.forename: Wouter J H
authors.initials: WJ
authors.lastname: Veldkamp
authors.forename: Bart J A
authors.initials: BJ
authors.lastname: Mertens
authors.forename: Mireille V
authors.initials: MV
authors.lastname: Boot
authors.forename: Jacob
authors.initials: J
authors.lastname: Geleijns
mesh_terms: D003951:Diagnostic Errors; D006801:Humans; D015588:Observer Variation; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000295:instrumentation*; D013902:Radiography, Thoracic / Q000295:instrumentation*; D013896:Thoracic Diseases / Q000000981:diagnostic imaging*