Acute dystonia induced by lamivudine.
Lamivudine is the most widely prescribed drug of choice for chronic hepatitis B infection, which is a common health problem in China. Generally, the administration of lamivudine has been well tolerated. The authors report two cases of acute dystonic reactions (ADRs) as a side effect of lamivudine. ADR induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs; however, there have been no reports of lamivudine-induced ADR in the English literature. The authors think that although lamivudine is widely used and well tolerated, it can cause ADRs, which are reversible after drug withdrawal.
Song
Xingwang
X
Department of Neurology, Second Xiangya Hospital, Central South University, Changsha, China. sxwlyq@hotmail.com
Hu
Zhiping
Z
Zhang
Hainan
H
D000208:Acute Disease; D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D001415:Back; D004421:Dystonia / Q000139:chemically induced* / Q000503:physiopathology; D019416:Head Movements; D019694:Hepatitis B, Chronic / Q000150:complications / Q000188:drug therapy; D006801:Humans; D019259:Lamivudine / Q000009:adverse effects*; D008297:Male; D009334:Neck Muscles / Q000503:physiopathology
D019380:Anti-HIV Agents; D019259:Lamivudine