Association of socioeconomic position with insulin resistance among children from Denmark, Estonia, and Portugal: cross sectional study.
OBJECTIVE
To examine the association between socioeconomic position and insulin resistance in children from three countries in northern Europe (Denmark), eastern Europe (Estonia), and southern Europe (Portugal) that have different physical, economic, and cultural environments.


METHODS
Cross sectional study.


METHODS
3189 randomly selected schoolchildren aged 9 and 15 years from Denmark (n = 933), Estonia (n = 1103), and Portugal (n = 1153).


METHODS
Insulin resistance (homoeostasis model assessment).


RESULTS
Family income and parental education were inversely associated with insulin resistance in Danish children but were positively associated with insulin resistance in Estonian and Portuguese children. Among Danish children, insulin resistance was 24% lower (95% confidence interval -38% to -10%) in those whose fathers had the most education compared with those with the least education. The equivalent results were 15% (2% to 28%) higher for Estonia and 19% (2% to 36%) higher for Portugal. These associations remained after adjustment for a range of covariates: -20% (-36% to -5%) for Denmark, 10% (-4% to 24%) for Estonia, and 18% (-1% to 31%) for Portugal. Strong statistical evidence supported differences between the associations in Denmark and those in the other two countries in both unadjusted and adjusted models (all P < 0.03).


CONCLUSIONS
Among Danish children, those with the most educated and highest earning parents had least insulin resistance, whereas the opposite was true for children from Estonia and Portugal.
Lawlor
Debbie A
DA
Department of Social Medicine, University of Bristol, Bristol BS8 2PR. d.a.lawlor@bristol.ac.uk
Harro
Maarike
M
Wedderkopp
Niels
N
Andersen
Lars Bo
LB
Sardinha
Luis B
LB
Riddoch
Chris J
CJ
Page
Angie S
AS
Anderssen
Sigmund A
SA
Froberg
Karsten
K
Stansbie
David
D
Davey Smith
George
G
D000293:Adolescent; D002648:Child; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D003718:Denmark; D004522:Educational Status; D004957:Estonia; D005260:Female; D006801:Humans; D007182:Income / Q000706:statistics & numerical data; D007333:Insulin Resistance; D008297:Male; D011174:Portugal; D012307:Risk Factors; D012923:Social Class