title: Self-expanding metal stents in the palliation of malignant dysphagia: outcome analysis in 100 consecutive patients.
abstract: SUMMARY. Patients with inoperable esophageal malignancy often undergo palliative self-expanding metal stent insertion. This analysis of cases shows that although such stents provide good palliation of dysphagia, complications frequently occur. Complications reported were pain after insertion, bleeding, food bolus impaction, stent migration and increased gastroesophageal reflux. Furthermore, in patients with esophageal adenocarcinoma, survival was less if the distal end of the stent entered the stomach, rather than lying entirely within the esophagus. Reduced survival, in this group with gastroesophageal junction tumors, may be a result of increased gastroesophageal reflux leading to pulmonary aspiration. Stents incorporating an antireflux valve have been shown to reduce symptomatic gastroesophageal reflux. It may be that such valves offer a survival advantage where stent insertion ablates the function of the lower esophageal sphincter. Further studies are needed to assess the role of antireflux stents on survival in patients with gastroesophageal junction tumors.
authors.affiliation: Department of Gastroenterology, Northern General Hospital, Herries Road, Sheffield, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Elphick
authors.forename: B A
authors.initials: BA
authors.lastname: Smith
authors.forename: J
authors.initials: J
authors.lastname: Bagshaw
authors.forename: S A
authors.initials: SA
authors.lastname: Riley
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D003680:Deglutition Disorders / Q000209:etiology / Q000628:therapy*; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000150:complications*; D004943:Esophagogastric Junction; D005260:Female; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D008670:Metals