Revision of the structure assigned to the antibiotic BU-4664L from Micromonopora.
The structure assigned to the antitumor antibiotic BU-4664L from Micromonospora sp. was revised to 5,10-dihydro-4,6,8-trihydroxy-10-(3,7,11-trimethyl-trans-2,trans-6,10-dodecatrienyl)-11H-dibenzo[b,e] [1,4]-diazepin-11-one based on the NMR analysis.
Igarashi
Yasuhiro
Y
Biotechnology Research Center, Toyama Prefectural University, 5180 Kurokawa, Kosugi, Toyama 939-0398, Japan. yas@pu-toyama.ac.jp
Miyanaga
Satoshi
S
Onaka
Hiroyasu
H
Takeshita
Michinori
M
Furumai
Tamotsu
T
D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000737:chemistry*; D003984:Dibenzazepines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008847:Micromonospora / Q000378:metabolism*; D008968:Molecular Conformation; D012717:Sesquiterpenes / Q000737:chemistry*
C502981:5,10-dihydro-4,6,8-trihydroxy-10-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-11H-dibenzo(b,e)(1,4)diazepin-11-one; D000903:Antibiotics, Antineoplastic; D003984:Dibenzazepines; D012717:Sesquiterpenes