Pro-neural factors and neurogenesis.
The role of pro-neural factors in specifying neuronal progenitors and in promoting neuronal differentiation is conserved from Drosophila to vertebrates. This primer discusses the basic functions of pro-neural factors in neurogenesis, mechanisms of pro-neural factor function, and models for how pro-neural factors generate neuronal subtypes. The primer also features a dialog about current topics and future directions in the field between two experts in neurogenesis: Andrew Jarman, Ph.D., and Jane Johnson, Ph.D.
Kiefer
Julie C
JC
Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA. julie.kiefer@hci.utah.edu
Jarman
Andrew
A
Johnson
Jane
J
D000818:Animals; D002454:Cell Differentiation; D018507:Gene Expression Regulation, Developmental; D009420:Nervous System / Q000166:cytology* / Q000196:embryology* / Q000378:metabolism; D009474:Neurons / Q000166:cytology* / Q000378:metabolism*