title: Incompatibility of oxalate desensitizers with acidic, fluoride-containing total-etch adhesives.
abstract: The use of oxalate desensitizers on acid-etched dentin prior to adhesive application can result in subsurface tubular occlusion by calcium oxalate crystals. However, the solubility of calcium oxalate increases in acidic solution. We hypothesized that total-etch adhesives can, depending upon their pH, interact with oxalate-desensitizer-treated dentin in an adverse manner. Acid-etched human dentin treated with 2 oxalate desensitizers (BisBlock and Super Seal) was bonded with 4 simplified total-etch adhesives: One-Step (OS), Single Bond (SB), OptiBond Solo Plus (OB), and Prime&Bond NT (PB). Composite-dentin beams were examined by SEM and TEM, both of which revealed numerous spherical globules on OB- and PB-bonded, desensitizer-treated dentin, but not in OS or SB samples. Bond strengths produced by OB and PB were significantly lower in oxalate-treated specimens than those produced by OS or SB. These surface globules may have interfered with hybridization of demineralized dentin with OB and PB resins and caused compromised bond strengths.
authors.affiliation: Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, 34 Hospital Road, Hong Kong SAR, China.
authors.forename: C K Y
authors.initials: CK
authors.lastname: Yiu
authors.forename: N M
authors.initials: NM
authors.lastname: King
authors.forename: B I
authors.initials: BI
authors.lastname: Suh
authors.forename: L J
authors.initials: LJ
authors.lastname: Sharp
authors.forename: R M
authors.initials: RM
authors.lastname: Carvalho
authors.forename: D H
authors.initials: DH
authors.lastname: Pashley
authors.forename: F R
authors.initials: FR
authors.lastname: Tay
mesh_terms: D000704:Analysis of Variance; D001840:Dental Bonding; D003799:Dental Stress Analysis; D003804:Dentin / Q000187:drug effects* / Q000648:ultrastructure; D003806:Dentin Permeability / Q000187:drug effects; D003807:Dentin Sensitivity; D017220:Dentin-Bonding Agents / Q000737:chemistry* / Q000494:pharmacology; D004344:Drug Incompatibility; D005459:Fluorides / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008422:Materials Testing; D008854:Microscopy, Electron; D010070:Oxalates / Q000737:chemistry* / Q000494:pharmacology; D019815:Oxalic Acid / Q000737:chemistry / Q000494:pharmacology; D019279:Resin Cements / Q000737:chemistry* / Q000494:pharmacology; D018709:Statistics, Nonparametric; D013718:Tensile Strength
chemical_list: C514542:BisBlock; D017220:Dentin-Bonding Agents; D010070:Oxalates; D019279:Resin Cements; C474198:SuperSeal; D019815:Oxalic Acid; D005459:Fluorides