title: [Morphogenesis of unstable atherosclerotic plaque and its role in development of acute coronary syndrome (ACS)].
abstract: There is a combination of inflammation inside unstable atherosclerotic plaque and reparation of its fibrous cover. Increase of the inflammation activity with production of various proteases results in thinning of fibrous cover and loss of normal intercellular and matrix-cell interactions. Later rupture of the plaque takes place with development of a variant of ACS.
authors.forename: L O
authors.initials: LO
authors.lastname: Severgin
mesh_terms: D000789:Angina, Unstable / Q000209:etiology*; D003324:Coronary Artery Disease / Q000150:complications* / Q000201:enzymology / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology*; D010447:Peptide Hydrolases / Q000378:metabolism; D013577:Syndrome
chemical_list: D010447:Peptide Hydrolases