title: Hemispheric integrative therapy in Landau-Kleffner syndrome: applications for rehabilitation sciences.
abstract: A case study is presented of a 14-year-old right-handed Caucasian female diagnosed with the Landau-Kleffner Syndrome (LKS) at the age 3 1/2 years. Her LKS symptoms presented with abrupt disruption in language after normal development, electroencephalogram (EEG) brain-wave abnormality, seizure activity, inability to read, and impairment in her motor skills. After 11 years of pharmacological and special education interventions with no significant improvement in any measurable area of function, a multimodal approach using techniques purportedly aimed at facilitating inter-hemispheric communication was provided. At completion of the program, EEG was controlled, reading, language, and auditory processing improved and objective behavioral-social measures improved significantly.
authors.affiliation: Department of Clinical Sciences, University of Bridgeport, CT, USA.
authors.forename: Victor M
authors.initials: VM
authors.lastname: Pedro
authors.forename: Gerry
authors.initials: G
authors.lastname: Leisman
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000473:pathology / Q000503:physiopathology*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D004569:Electroencephalography; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation*; D007806:Language Disorders / Q000175:diagnosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008774:Methylphenidate / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D014635:Valproic Acid / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D000697:Central Nervous System Stimulants; D008774:Methylphenidate; D014635:Valproic Acid