title: Analysis of recombination in Campylobacter jejuni from MLST population data.
abstract: We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225-750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.
authors.affiliation: Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, UK. p.fearnhead@lancs.ac.uk
authors.forename: Paul
authors.initials: P
authors.lastname: Fearnhead
authors.forename: Nick G C
authors.initials: NG
authors.lastname: Smith
authors.forename: Mishele
authors.initials: M
authors.lastname: Barrigas
authors.forename: Andrew
authors.initials: A
authors.lastname: Fox
authors.forename: Nigel
authors.initials: N
authors.lastname: French
mesh_terms: D000818:Animals; D016123:Campylobacter jejuni / Q000235:genetics* / Q000302:isolation & purification*; D020869:Gene Expression Profiling; D006239:Haplotypes; D016296:Mutagenesis / Q000235:genetics; D011995:Recombination, Genetic / Q000235:genetics*; D014871:Water Microbiology