Superparamagnetic gadonanotubes are high-performance MRI contrast agents.
We report the nanoscale loading and confinement of aquated Gd3+n-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes); these Gd3+n@US-tube species are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd3+-based contrast agent (CA) in current clinical use.
Sitharaman
B
B
Department of Chemistry, the Center for Nanoscale Science and Technology, and the Center for Biological and Environmental Nanotechnology MS 60, Rice University, Houston, Texas 77251-1892, USA.
Kissell
K R
KR
Hartman
K B
KB
Tran
L A
LA
Baikalov
A
A
Rusakova
I
I
Sun
Y
Y
Khant
H A
HA
Ludtke
S J
SJ
Chiu
W
W
Laus
S
S
Tóth
E
E
Helm
L
L
Merbach
A E
AE
Wilson
L J
LJ
D003287:Contrast Media; D005682:Gadolinium / Q000737:chemistry*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D043942:Nanotubes
D003287:Contrast Media; D005682:Gadolinium