title: Encapsulating peritoneal sclerosis is a separate entity: Con.
abstract: There is controversy with respect to the issue that encapsulating peritoneal sclerosis (EPS) is a separate entity from simple sclerosis (SS), which is the uniform change of the peritoneum on peritoneal dialysis. These following ideas support the notion that the development of EPS is connected with pathology that is not the same as that responsible for SS: (1) EPS is a rare disorder, (2) certain factors are involved with the etiology, (3) the clinical background of the patients is not uniform, and (4) the histopathological findings of EPS are different from those of SS. There are pitfalls in these concepts and they need be revised. This paper discusses the issue against the idea that EPS is a separate entity, supporting the idea that it has a strong connection with SS in its primary pathophysiology.
authors.affiliation: Division of Kidney and Hypertension, Tokyo Jikei University School of Medicine, Tokyo, Japan. mnakayama@jikei.ac.jp
authors.forename: Masaaki
authors.initials: M
authors.lastname: Nakayama
authors.forename: Yukio
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Miwako
authors.initials: M
authors.lastname: Numata
mesh_terms: D006801:Humans; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010532:Peritoneal Diseases / Q000209:etiology / Q000473:pathology*; D010537:Peritoneum / Q000473:pathology; D012598:Sclerosis