Antioxidative phenols and phenolic glycosides from Curculigo orchioides.
A new orcinol glucoside, orcinol-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (3), was isolated from the rhizomes of Curculigo orchioides GAERTN., together with seven known compounds: orcinol glucoside (1), orcinol-1-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (2), curculigoside (4), curculigoside B (5), curculigoside C (6), 2,6-dimethoxyl benzoic acid (7), and syringic acid (8). The structures of these compounds were elucidated using spectroscopic methods. The antioxidant activities of these isolated compounds were evaluated by colorimetric methods based on their scavenging effects on hydroxyl radicals and superoxide anion radicals, respectively. All the compounds showed potent antioxidative activities and the structure-activity relationship is discussed.
Wu
Qiong
Q
Research Center of Natural Medicines, Fudan University, Shanghai 200433, PR China.
Fu
Da-Xu
DX
Hou
Ai-Jun
AJ
Lei
Guang-Qing
GQ
Liu
Zhi-Jun
ZJ
Chen
Jia-Kuan
JK
Zhou
Tong-Shui
TS
D000975:Antioxidants / Q000302:isolation & purification*; D031408:Curculigo / Q000737:chemistry*; D006027:Glycosides / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013329:Structure-Activity Relationship
D000975:Antioxidants; D006027:Glycosides; D010636:Phenols