Paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma and good response to prednisone.
Paraneoplastic pemphigus is a life-threatening autoimmune bullous disease associated with neoplasia, generally of lymphoid origin. Immunosuppressive therapy is often disappointing and there are only a few reports of patients surviving more than 2 years. These cases were generally associated with benign neoplasms. We report here the case of a patient with paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma who had a surprisingly good response to systemic corticosteroids and remains free of lesions more than 3 years later despite progression of her neoplasm.
Martínez De Pablo
María Isabel
MI
Servicio de Dermatologia, Hospital Clinic, C/Villaroel 170, ES-08036 Barcelona, Spain. 34199mmd@comb.es
Iranzo
Pilar
P
Mascaró
José Manuel
JM
Llambrich
Alex
A
Baradad
Manel
M
Herrero
Carmen
C
D000368:Aged; D003937:Diagnosis, Differential; D004334:Drug Administration Schedule; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D019226:Oral Ulcer / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010392:Pemphigus / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000008:administration & dosage
D005938:Glucocorticoids; D011241:Prednisone