A brief overview of the clinical pharmacology of "club drugs".
Four different "club drugs" are reviewed: MDMA (methylenedioxymethamphetamine, "Ecstasy"), GHB (gamma-hydroxybutyrate), ketamine, and Rohypnol (flunitrazepam). The neurobiology, clinical pharmacology, and treatment issues for each are discussed.
Britt
Gena Covell
GC
Division of Addiction Psychiatry, Virginia Commonwealth University, Richmond, Virginia 23219, USA. gcbritt@vcu.edu
McCance-Katz
Elinore F
EF
D000759:Adjuvants, Anesthesia / Q000009:adverse effects* / Q000494:pharmacology*; D000778:Anesthetics, Dissociative / Q000009:adverse effects* / Q000494:pharmacology*; D003615:Dancing; D005445:Flunitrazepam; D018757:GABA Modulators / Q000009:adverse effects* / Q000494:pharmacology*; D006213:Hallucinogens / Q000009:adverse effects* / Q000494:pharmacology*; D006801:Humans; D013287:Illicit Drugs; D007649:Ketamine / Q000009:adverse effects*; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects* / Q000494:pharmacology*; D011998:Recreation; D012978:Sodium Oxybate / Q000009:adverse effects* / Q000494:pharmacology*; D019966:Substance-Related Disorders / Q000628:therapy
D000759:Adjuvants, Anesthesia; D000778:Anesthetics, Dissociative; D018757:GABA Modulators; D006213:Hallucinogens; D013287:Illicit Drugs; D005445:Flunitrazepam; D007649:Ketamine; D012978:Sodium Oxybate; D018817:N-Methyl-3,4-methylenedioxyamphetamine