title: Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum.
abstract: A small but significant excess of deaths for tumors of the digestive system has been described in Crohn's disease. In a study analyzing all cancers of the small intestine within a defined population, Crohn's disease was the major underlying factor for cancer of the small intestine. Areas of the small intestine containing strictures are unusually prone to malignant transformation. We report the rare case of a patient in whom surgery for intestinal occlusion disclosed Crohn's disease of the distal ileum complicated by two adenocarcinomas arising within distinct areas of the inflamed bowel.
authors.affiliation: Dipartimento di Chirurgia P. Valdoni, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185, Rome, Italy. paolo.sammartino@uniroma1.it
authors.forename: P
authors.initials: P
authors.lastname: Sammartino
authors.forename: S
authors.initials: S
authors.lastname: Sibio
authors.forename: A
authors.initials: A
authors.lastname: Di Giorgio
authors.forename: R
authors.initials: R
authors.lastname: Caronna
authors.forename: A
authors.initials: A
authors.lastname: Viscido
authors.forename: M
authors.initials: M
authors.lastname: Zippi
authors.forename: D
authors.initials: D
authors.lastname: Biacchi
authors.forename: F
authors.initials: F
authors.lastname: Accarpio
authors.forename: P
authors.initials: P
authors.lastname: Mingazzini
authors.forename: R
authors.initials: R
authors.lastname: Caprilli
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D003424:Crohn Disease / Q000175:diagnosis*; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D033162:Incidental Findings; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery; D008297:Male