title: Microbial transformation of mestranol by Cunninghamella elegans.
abstract: The microbial transformation of an oral contraceptive, mestranol (1) by Cunninghamella elegans yielded two hydroxylated metabolites, 6beta-hydroxymestranol (2) and 6beta,12beta-dihydroxymestranol (3). Metabolite 3 was found to be a new compound. These metabolites were structurally characterized on the basis of spectroscopic techniques.
authors.affiliation: International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. hej@cyber.net.pk
authors.forename: Muhammad Iqbal
authors.initials: MI
authors.lastname: Choudhary
authors.forename: Syed Ghulam
authors.initials: SG
authors.lastname: Musharraf
authors.forename: Zafar Ali
authors.initials: ZA
authors.lastname: Siddiqui
authors.forename: Naik Tameen
authors.initials: NT
authors.lastname: Khan
authors.forename: Rahat Azhar
authors.initials: RA
authors.lastname: Ali
authors.forename: Atta
authors.initials: A
authors.lastname: Ur-Rahman
mesh_terms: D001711:Biotransformation; D020093:Cunninghamella / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008656:Mestranol / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D008656:Mestranol