MDMA (ecstasy) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers.
de la Torre
Rafael
R
Pharmacology Unit, Institut Municipal d'Investigació Mèdica (IMIM), Doctor Aiguader 80, 08003 Barcelona, Spain. rtorre@imim.es
Farré
Magí
M
Mathúna
Brian O
BO
Roset
Pere N
PN
Pizarro
Neus
N
Segura
Mireia
M
Torrens
Marta
M
Ortuño
Jordi
J
Pujadas
Mitona
M
Camí
Jordi
J
D019540:Area Under Curve; D018592:Cross-Over Studies; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism*; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000493:pharmacokinetics*; D010919:Placebos
D010919:Placebos; D019389:Cytochrome P-450 CYP2D6; D018817:N-Methyl-3,4-methylenedioxyamphetamine