title: [Premature separation of the placenta--etiology and risk factors].
abstract: OBJECTIVE
  Placental abruption complicates approximately 1% of all pregnancies and remains a significant cause of both maternal and fetal morbidity and mortality. Several risk factors are associated with this complications, but a clear causal relation is diffucult to establish.
  
  
  OBJECTIVE
  The aim of the study was to determine and identify risk factors for placental abruption.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Dept. of Obstetrics and Gynaecology, Medical Faculty of Palacký University, Olomouc.
  
  
  METHODS
  Retrospectively gathered cohort of 180 women was compared to 198 healthy women. We have focused on anthropometric, sociodemographic, behavioral, obstetric and fetal parameters. Statistical evaluation was done by Statsoft, Inc. (2001) Statistika CZ (Software system data analysis), version 6.
  
  
  RESULTS
  The incidence of the placental abruption was 0.89%. We have confirmed the following risk factors as statistically significant (p values are given): Low-degree education (0.00002), prepregnancy weight of the mother (0.00), weight gain in pregnancy (0.00), higher parity (0.0272), smoking (0.03847), preeclampsia (0.00889), chorioamnionitis (0.00), premature rupture of membranes (0.00), recurrent spontaneous abortions (0.00), positive family history of deep venous thrombosis (0.0007) and intrauterine growth retardation (0.0386).
  
  
  CONCLUSIONS
  Placental abruption has a large number of potential risk factors. The true biological cause and its etiopathogenic role is still to be elucidated.
authors.affiliation: Porodnicko-gynekologická klinika LF UP, Olomouc. martinprochazka@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Procházka
authors.forename: M
authors.initials: M
authors.lastname: Kudela
authors.forename: M
authors.initials: M
authors.lastname: Lubuský
authors.forename: M
authors.initials: M
authors.lastname: Vĕtr
authors.forename: P
authors.initials: P
authors.lastname: Hrachovec
authors.forename: P
authors.initials: P
authors.lastname: Zielina
mesh_terms: D000037:Abruptio Placentae / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D012307:Risk Factors