The Ni-mediated cyclocarbonylation of allyl halides and alkynes made catalytic. Evidence supporting the involvement of pseudoradical Ni(i) species in the mechanism.
We report here on a highly efficient catalytic method to synthesize intermolecularly the cyclopentane skeleton from starting products as simple as allyl halides, alkynes, and carbon monoxide under very mild reaction conditions by means of a substoichiometric amount of iron, acetone, and a catalytic amount of Ni(II) iodide.
Nadal
M Lluïsa
ML
Laboratori de Catálisi Homogenea, Institut de Ciència de Materials de Barcelona, (CSIC) Campus de la UAB, 08193 Bellaterra, Spain.
Bosch
Julia
J
Vila
Josep M
JM
Klein
Günter
G
Ricart
Susagna
S
Moretó
Josep M
JM