[The relationship between microalbuminuria and plasma high sensitivity C reactive protein].
OBJECTIVE
To investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).


METHODS
The plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.


RESULTS
The hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).


CONCLUSIONS
Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.
Yan
Jiang-tao
JT
Department of Internal Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ye
Hui
H
Wang
Dao-wen
DW
D000368:Aged; D000419:Albuminuria / Q000652:urine*; D044466:Asian People; D002097:C-Reactive Protein / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged
D002097:C-Reactive Protein