Lewis base catalyzed ring opening of aziridines with silylated nucleophiles.
The ring opening of N-tosylaziridines with trimethylsilylated nucleophiles, catalyzed by N,N,N',N'-tetramethylethylenediamine, led to the production of beta-functionalized sulfonamides in good to excellent yields with high regioselectivity. [reaction: see text]
Minakata
Satoshi
S
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan.
Okada
Yuriko
Y
Oderaotoshi
Yoji
Y
Komatsu
Mitsuo
M