title: The Leptospira interrogans lexA gene is not autoregulated.
abstract: Footprinting and mutagenesis experiments demonstrated that Leptospira interrogans LexA binds the palindrome TTTGN(5)CAAA found in the recA promoter but not in the lexA promoter. In silico analysis revealed that none of the other canonical SOS genes is under direct control of LexA, making the leptospiral lexA gene the first described which is not autoregulated.
authors.affiliation: Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Cuñé
authors.forename: Paul
authors.initials: P
authors.lastname: Cullen
authors.forename: Gerard
authors.initials: G
authors.lastname: Mazon
authors.forename: Susana
authors.initials: S
authors.lastname: Campoy
authors.forename: Ben
authors.initials: B
authors.lastname: Adler
authors.forename: Jordi
authors.initials: J
authors.lastname: Barbe
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D018983:DNA Footprinting; D004260:DNA Repair / Q000502:physiology; D006706:Homeostasis / Q000235:genetics*; D007921:Leptospira interrogans / Q000235:genetics*; D008969:Molecular Sequence Data; D016296:Mutagenesis; D012697:Serine Endopeptidases / Q000235:genetics*; D014158:Transcription, Genetic / Q000502:physiology; D000099160:LexA Repressor Protein
chemical_list: D001426:Bacterial Proteins; D012697:Serine Endopeptidases; D000099160:LexA Repressor Protein