title: Pulmonary alveolar proteinosis and end-stage pulmonary fibrosis: a rare association.
abstract: We present the high resolution CT features of marked pulmonary fibrosis in a patient known to have pulmonary alveolar proteinosis (PAP) confirmed on open lung biopsy. Significant fibrosis in PAP is an extremely rare occurrence with only a few case reports. Our case demonstrated a predominantly central distribution, which has not been described previously.
authors.affiliation: Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, Ontario, Canada.
authors.forename: Prachi P
authors.initials: PP
authors.lastname: Agarwal
authors.forename: Jean M
authors.initials: JM
authors.lastname: Seely
authors.forename: D Garth
authors.initials: DG
authors.lastname: Perkins
authors.forename: Fred R
authors.initials: FR
authors.lastname: Matzinger
authors.forename: Qasim
authors.initials: Q
authors.lastname: Alikhan
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D010784:Photomicrography; D011649:Pulmonary Alveolar Proteinosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed