Synthesis of a new chiral N,N,N-tridentate pyridinebisimidazoline ligand library and its application in Ru-catalyzed asymmetric epoxidation.
A small ligand library of chiral tridentate N,N,N-pyridinebisimidazolines have been synthesized for the first time. This new class of ligands can be easily tuned and synthesized on multi g-scale. The usefulness of the ligands is shown in the ruthenium-catalyzed asymmetric epoxidation with hydrogen peroxide as oxidant. Excellent yields (>99%) and good enantioselectivities (up to 71% ee) have been obtained for the epoxidation of aromatic olefins. [reaction: see text]
Bhor
Santosh
S
Leibniz-Institut für Organische Katalyse (IfOK) an der Universität Rostock e.V., Albert-Einstein-Strasse 29A, D-18059 Rostock, Germany.
Anilkumar
Gopinathan
G
Tse
Man Kin
MK
Klawonn
Markus
M
Döbler
Christian
C
Bitterlich
Bianca
B
Grotevendt
Anne
A
Beller
Matthias
M