The prognosis of hearing impairment complicating HIV-negative cryptococcal meningitis.
Eight patients who had sensorineural hearing loss (SNHL) associated with cryptococcal meningitis were studied. After a minimum 3-year follow-up, one had died. Among the seven survivors, three had improved, two stabilized, and two progressed. Predictive factors included visual disturbance, meningeal enhancements on MRI, and a CSF cryptococcal antigen titer of >1:1,024. SNHL accounted for 30.8% (8/26) of cryptococcal meningitis patients in our study.
Wang
H-C
HC
Department of Neurology, Chang Gung Memorial Hospital, 123, Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan.
Chang
W-N
WN
Lui
C-C
CC
Peng
J-P
JP
Huang
C-R
CR
Chang
H-W
HW
Liliang
P-C
PC
Lu
C-H
CH
D000328:Adult; D000368:Aged; D000946:Antigens, Fungal / Q000134:cerebrospinal fluid; D001100:Arachnoiditis / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D001299:Audiometry; D003051:Cochlea / Q000473:pathology / Q000503:physiopathology*; D003056:Cochlear Nerve / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D018023:HIV Seronegativity; D006319:Hearing Loss, Sensorineural / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000175:diagnosis*; D008875:Middle Aged; D009900:Optic Nerve / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D011237:Predictive Value of Tests; D011379:Prognosis; D015996:Survival Rate; D014786:Vision Disorders / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology
D000946:Antigens, Fungal