title: Acitretin-induced enthesitis in a patient with psoriatic arthritis.
abstract: A patient with psoriatic arthritis and cutaneous psoriasis took acitretin for 10 years to treat his skin lesions. Radiographs disclosed exuberant ossifications in several entheses. Their features were not typical for psoriatic arthritis but were consistent with acitretin-induced hyperostosis. Retinoids are known to induce hyperostosis, most notably when they are used in high dosages and over long periods. The concomitant presence of two conditions affecting the entheses may explain the exuberant nature of the ossifications in our patient.
authors.affiliation: Rheumatology Department, CHU Purpan Teaching Hospital, place du Docteur Baylac, 31059 Toulouse, France. fournie.b@chu-toulouse.fr
authors.forename: Véronique
authors.initials: V
authors.lastname: Vincent
authors.forename: Laurent
authors.initials: L
authors.lastname: Zabraniecki
authors.forename: Olivier
authors.initials: O
authors.lastname: Loustau
authors.forename: Bertrand
authors.initials: B
authors.lastname: Godfrin
authors.forename: Frédérique Bertrand
authors.initials: FB
authors.lastname: Latour
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Railhac
authors.forename: Bernard
authors.initials: B
authors.lastname: Fournié
mesh_terms: D017255:Acitretin / Q000009:adverse effects* / Q000627:therapeutic use; D000843:Ankle Joint / Q000000981:diagnostic imaging; D015535:Arthritis, Psoriatic / Q000000981:diagnostic imaging / Q000188:drug therapy*; D001175:Arthrography; D005500:Follow-Up Studies; D006801:Humans; D007641:Keratolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008023:Ligaments, Articular / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin