title: Lipoprotein retention--and clues for atheroma regression.
abstract: Subendothelial retention of apoB-lipoproteins is the key initiating event in atherosclerosis, provoking a cascade of pathogenic responses. Dissection of the molecular participants provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids derived from retained lipoproteins may be crucial in promoting beneficial remodeling of lesions.
authors.forename: Kevin Jon
authors.initials: KJ
authors.lastname: Williams
authors.forename: Ira
authors.initials: I
authors.lastname: Tabas
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000378:metabolism* / Q000473:pathology*; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*
chemical_list: D008074:Lipoproteins