title: Gaudichanolides A and B, clerodane diterpenes from Baccharis gaudichaudiana.
abstract: Two new clerodane diterpenoids, gaudichanolides A (1) and B (2), were isolated from the dried twigs of Baccharis gaudichaudiana, together with 7-oxo-16,19-dihydroxy-3,4-dehydroclerodan-15,20-diacid dilactone, spathulenol, 4,10-aromadendranediol, kobusone, trans-cosanyl ferulate, and defuscin. The structures and relative stereochemistry of 1 and 2 were elucidated by detailed 2D NMR spectroscopic experiments, and the absolute stereochemistry of 1 was determined by X-ray crystallographic analysis.
authors.affiliation: Department of Biochemistry, Okayama University of Science, 1-1 Ridai-cho, Okayama City, 700-0005 Japan.
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Hayashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanamori
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yamazoe
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nozaki
mesh_terms: D031175:Baccharis / Q000737:chemistry*; D001938:Brazil; D018360:Crystallography, X-Ray; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D045785:Diterpenes, Clerodane; C503033:gaudichanolide A; C503034:gaudichanolide B