A total synthesis of (+/-)-trans-kumausyne.
A short total synthesis of (+/-)-trans-kumausyne is reported. Key steps include a tandem ring-opening-ring-closing metathesis and the effective introduction of the pentenyl side chain by allylation-cross metathesis. [reaction: see text]
Chandler
Carley L
CL
Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, CO 80309-0215, USA.
Phillips
Andrew J
AJ
D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D044722:Laurencia / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D005663:Furans; C510440:kumausyne