title: [The effect of preparation method on the quality of shen-mai injection].
abstract: OBJECTIVE
  To investigate the effect of different preparation method on the quality of Shen-mai injection.
  
  
  METHODS
  The Shen-mai injection samples were prepared using three different methods. Fingerprints of Shen-mai extracts red ginseng, and its intermediates were obtained using an HPLC analytical procedure. The contents of ginsenoside Rg1, Rc and Rb1, and the gross saponins of Shen-mai extract were quantitatively mensured with HPLC procedures.
  
  
  RESULTS
  There was significant difference in fingerprints and chemical contents of the injections prepared by the three different methods.
  
  
  CONCLUSIONS
  The quality of Shen-mai injection was greatly influenced by the preparation method. HPLC fingerprinting method can be applied for the determination of the Shen-mai preparations.
authors.affiliation: Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
authors.forename: Yong-jiang
authors.initials: YJ
authors.lastname: Wu
authors.forename: Qin-min
authors.initials: QM
authors.lastname: Cui
authors.forename: Yi-yu
authors.initials: YY
authors.lastname: Cheng
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D036145:Ginsenosides / Q000032:analysis; D007267:Injections; D031441:Ophiopogon / Q000737:chemistry; D005894:Panax / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011786:Quality Control; D012503:Saponins / Q000032:analysis; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D012503:Saponins; C044462:ginsenoside Rc; C442759:ginsenoside Rb1; C035054:ginsenoside Rg1