title: ACTH response to LPS in the first stages of development of the fish Dicentrarchus labrax L.
abstract: ACTH and ACTH receptor-like molecules were found at the examined stages of development (2, 4, 8, 12, 18, and 24 days post-hatching) in yolk sac, pronephros tubules, interrenal tissue, thymus, liver, spleen, cardinal veins, and skin of the teleost fish Dicentrarchus labrax. ACTH and the related receptor-like molecules show a similar distribution. LPS treatment at two different stages (8 and 24 days post-hatching) provoked both a release and an induction of ACTH-like molecules, suggesting an important role of this peptide to control the modifications in body homeostasis during the first period of the sea bass' life, i.e., 30 days post-hatching, before the lymphoid cells have reached complete maturation.
authors.affiliation: Department of Animal Biology, University of Modena and Reggio Emilia, via Campi 213/D, I-41100 Modena, Italy.
authors.forename: Lucrezia
authors.initials: L
authors.lastname: Mola
authors.forename: Andrea
authors.initials: A
authors.lastname: Gambarelli
authors.forename: Aurora
authors.initials: A
authors.lastname: Pederzoli
authors.forename: Enzo
authors.initials: E
authors.lastname: Ottaviani
mesh_terms: D000222:Adaptation, Physiological / Q000276:immunology; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D001492:Bass / Q000196:embryology / Q000276:immunology* / Q000378:metabolism; D006706:Homeostasis / Q000276:immunology; D007107:Immune System / Q000196:embryology / Q000276:immunology / Q000378:metabolism; D007150:Immunohistochemistry; D007401:Interrenal Gland / Q000196:embryology / Q000276:immunology* / Q000378:metabolism; D007668:Kidney / Q000196:embryology / Q000276:immunology* / Q000378:metabolism; D008070:Lipopolysaccharides / Q000276:immunology*; D008099:Liver / Q000196:embryology / Q000276:immunology / Q000378:metabolism; D009490:Neurosecretory Systems / Q000196:embryology / Q000276:immunology / Q000378:metabolism; D018043:Receptors, Corticotropin / Q000378:metabolism*; D015398:Signal Transduction / Q000276:immunology; D013950:Thymus Gland / Q000196:embryology / Q000276:immunology / Q000378:metabolism; D014018:Tissue Distribution; D015017:Yolk Sac / Q000276:immunology / Q000378:metabolism
chemical_list: D008070:Lipopolysaccharides; D018043:Receptors, Corticotropin; D000324:Adrenocorticotropic Hormone