Bone mineral content in calcium renal stone formers.
Idiopathic renal calcium stone disease often presents with reduced bone mineral content. Investigations using non-invasive methods for the measurement of bone mineral content (single and dual-photon absorptiometry, dual-energy x-ray absorptiometry, quantitative computed tomodensitometry) show a slight decrease in skeletal mineral content of idiopathic renal stone formers (RSFs). The alterations in bone mineral content in RSFs have different explanations: prostaglandin-mediated bone resorption, subtle metabolic acidosis and 1-25 vitamin D disorders. Bone mineral content is worsened by insufficient dietary calcium leading to a negative calcium balance.
Trinchieri
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Urology Unit, Ospedale A. Manzoni, Via dell'Eremo 9/11, 23800 Lecco, Italy. a.trinchieri@ospedale.lecco.it
D000818:Animals; D015519:Bone Density; D002118:Calcium / Q000378:metabolism*; D002136:Calcium, Dietary / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000378:metabolism; D007669:Kidney Calculi / Q000378:metabolism*; D014807:Vitamin D / Q000378:metabolism
D002136:Calcium, Dietary; D004044:Dietary Proteins; D014807:Vitamin D; D002118:Calcium