Important role for methionine sulfoxide reductase in the oxidative stress response of Xanthomonas campestris pv. phaseoli.
A methionine sulfoxide reductase gene (msrA) from Xanthomonas campestris pv. phaseoli has unique expression patterns and physiological function. msrA expression is growth dependent and is highly induced by exposure to oxidants and N-ethylmaleimide in an OxyR- and OhrR-independent manner. An msrA mutant showed increased sensitivity to oxidants but only during stationary phase.
Vattanaviboon
Paiboon
P
Laboratory of Biotechnology, Chulabhorn Research Institute, Lak Si, Bangkok 10210, Thailand. paiboon@cri.or.th
Seeanukun
Chotirote
C
Whangsuk
Wirongrong
W
Utamapongchai
Supa
S
Mongkolsuk
Skorn
S
D003001:Cloning, Molecular; D015964:Gene Expression Regulation, Bacterial; D015971:Gene Expression Regulation, Enzymologic; D051150:Methionine Sulfoxide Reductases; D016877:Oxidants / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology*; D010088:Oxidoreductases / Q000235:genetics* / Q000378:metabolism*; D016959:Xanthomonas campestris / Q000201:enzymology* / Q000235:genetics* / Q000254:growth & development
D016877:Oxidants; D010088:Oxidoreductases; D051150:Methionine Sulfoxide Reductases; C027219:methionine sulfoxide reductase