title: Neurosurgical approach to treating pituitary adenomas.
abstract: The transsphenoidal route remains the dominant surgical approach to the management of pituitary adenomas. These tumors may present clinically with signs or symptoms related to hypersecretion, hypopituitarism, or mass effect; or they may be identified incidentally during neuroimaging for management of other disorders. Diagnostic and treatment strategies for pituitary adenomas are reviewed. In addition, we present outcomes data from a large number of patients treated over a 30-year period by a single neurosurgeon. In our experience, transsphenoidal surgery for pituitary adenomas is associated with low rates of morbidity, mortality, and disease recurrence.
authors.affiliation: Department of Neurosurgery, University of Virginia, UVA Medical Center, PO Box 800212, Charlottesville, VA 22908, USA. el5g@virginia.edu
authors.forename: Edward R
authors.initials: ER
authors.lastname: Laws
authors.forename: John A
authors.initials: JA
authors.lastname: Jane
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D019635:Neurosurgical Procedures; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery*