title: From bedside to bench: research agenda for frailty.
abstract: The American Geriatrics Society sponsored a working conference in January 2004, funded by the National Institute on Aging, to establish the state of the art in frailty research and to set a research agenda for the future. The invited participants included senior basic biologists, epidemiologists, geneticists, and clinical investigators who study aging-related issues. This article summarizes the central theoretical observations on frailty and research needs and opportunities presented and discussed at this conference, and lays out an agenda for future research on frailty.
authors.affiliation: Center on Aging and Health and Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. lfried@jhmi.edu [corrected]
authors.forename: Linda P
authors.initials: LP
authors.lastname: Fried
authors.forename: Evan C
authors.initials: EC
authors.lastname: Hadley
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Walston
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.forename: Anne
authors.initials: A
authors.lastname: Newman
authors.forename: Jack M
authors.initials: JM
authors.lastname: Guralnik
authors.forename: Stephanie
authors.initials: S
authors.lastname: Studenski
authors.forename: Tamara B
authors.initials: TB
authors.lastname: Harris
authors.forename: William B
authors.initials: WB
authors.lastname: Ershler
authors.forename: Luigi
authors.initials: L
authors.lastname: Ferrucci
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D016330:Frail Elderly; D006801:Humans; D009316:National Institutes of Health (U.S.); D012106:Research / Q000639:trends; D014481:United States