Intermolecular rhodium-catalyzed [2+2+2] carbocyclization reactions of 1,6-enynes with symmetrical and unsymmetrical alkynes.
The crossed intermolecular rhodium-catalyzed [2+2+2] carbocyclization of carbon and heteroatom tethered 1,6-enynes can be accomplished with symmetrical and unsymmetrical alkynes, to afford the corresponding bicyclohexadienes in an efficient and highly selective manner.
Evans
P Andrew
PA
Department of Chemistry, Indiana University, Bloomington, IN 47405, USA. paevans@indiana.edu
Sawyer
James R
JR
Lai
Kwong Wah
KW
Huffman
John C
JC
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D012238:Rhodium / Q000737:chemistry*
D000480:Alkynes; D012238:Rhodium