Higher mortality risk of lungs carcinoma in vineyard sprayers.
This study investigated mortality rate of lungs carcinoma in professional vineyard sprayers. Clinical investigation was performed in 187 professional vineyard sprayers who had been exposed to the inhalation of the particles of Bordeaux mixture for 24 years on average. Bordeaux Mixture is used for prevention against mildew attacking vineyards. The control group was composed of 187 inhabitants of the same area who did not have any contact with the mentioned substance. A cytological investigation of the sputum specimens obtained from 104 tested inhabitants was performed. The sputum specimens were stained with standard haematoxylin-eosin method and also with special method (rubeanic acid) to prove the incidence of copper granules in macrophages. The findings show a considerable statistical difference in the frequency of occurrence of lungs carcinoma between the group of vineyard sprayers smokers and the control group (X2=4.77,p<0.01). The risk of lungs carcinoma in the vineyard sprayers was three times higher compared to the risk of smokers in the control group, with a statistical probability of 95% in the scope from 1.16<RR<7.78. Mortality risk of lungs carcinoma in the professional vineyard sprayers is significantly higher (p<0.01) compared to the risk in the control group.
Santić
Zarko
Z
Institute of Internal Medicine, Faculty of Medicine, University of Mostar, Bijeli brijeg b.b., 88000 Mostar, Bosnia and Herzegovina.
Puvacić
Zlatko
Z
Radović
Svjetlana
S
Puvacić
Sandra
S
D000395:Air Pollutants, Occupational / Q000506:poisoning*; D017522:Bosnia and Herzegovina / Q000453:epidemiology; D002277:Carcinoma / Q000139:chemically induced / Q000401:mortality* / Q000473:pathology; D003300:Copper / Q000506:poisoning*; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced / Q000401:mortality* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D012307:Risk Factors; D013183:Sputum / Q000166:cytology; D015996:Survival Rate / Q000639:trends
D000395:Air Pollutants, Occupational; D003300:Copper; C006788:Bordeaux mixture