title: Dendrimeric micelles for controlled drug release and targeted delivery.
abstract: This review highlights the developments in dendrimer-based micelles for drug delivery. Dendrimers, the perfectly branched monodisperse macromolecules, have certain structural advantages that make them attractive candidates as drug carriers for controlled release or targeted delivery. As polymeric micelle-based approaches precede the work in dendrimers, these are also discussed briefly. The review concludes with a perspective on possible applications of biaryl-based dendrimeric micelles that exhibit environment-dependent conformations, in drug delivery.
authors.affiliation: Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
authors.forename: Ashootosh V
authors.initials: AV
authors.lastname: Ambade
authors.forename: Elamprakash N
authors.initials: EN
authors.lastname: Savariar
authors.forename: S
authors.initials: S
authors.lastname: Thayumanavan
mesh_terms: D000666:Amphotericin B / Q000737:chemistry; D004337:Drug Carriers; D016503:Drug Delivery Systems / Q000379:methods*; D046911:Macromolecular Substances; D008823:Micelles; D015394:Molecular Structure; D011073:Polyamines; D011092:Polyethylene Glycols
chemical_list: D004337:Drug Carriers; D046911:Macromolecular Substances; D008823:Micelles; D011073:Polyamines; D011092:Polyethylene Glycols; D000666:Amphotericin B