Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi.
A highly oxygenated phenolic spiroketone, limnophilaspiroketone (1), was isolated from the aerial parts of Limnophila geoffrayi collected in Thailand. The structure of 1 was determined based on spectroscopic data interpretation. This novel isolate, obtained as a major secondary metabolite constituent, was verified as a racemate using the Mosher ester method.
Jang
Dae Sik
DS
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Su
Bao-Ning
BN
Pawlus
Alison D
AD
Jones
William P
WP
Kleps
Robert A
RA
Bunyapraphatsara
Nuntavan
N
Fong
Harry H S
HH
Pezzuto
John M
JM
Kinghorn
A Douglas
AD
D000818:Animals; D051379:Mice; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D028083:Scrophulariaceae / Q000737:chemistry*; D013785:Thailand; D014407:Tumor Cells, Cultured
D010636:Phenols; C503040:limnophilaspiroketone