title: Allele-specific genotyping by using guanine and gold electrochemical oxidation signals.
abstract: Electrochemical DNA biosensors have become strong candidates for DNA based analysis. Allele-specific genotyping is also one of the important research areas, where electrochemical approaches provide promising advances. Recently reported two methods based on electrochemical guanine and colloidal gold (Au) nanoparticle oxidation signals are reviewed and compared with the existing genotyping methods in this report.
authors.affiliation: Ege University, Faculty of Pharmacy, Analytical Chemistry Department, 35100 Bornova, Izmir, Turkey. ozsozs@pharm.ege.edu.tr
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozsoz
authors.forename: Arzum
authors.initials: A
authors.lastname: Erdem
authors.forename: Dilsat
authors.initials: D
authors.lastname: Ozkan
authors.forename: Pinar
authors.initials: P
authors.lastname: Kara
authors.forename: Hakan
authors.initials: H
authors.lastname: Karadeniz
authors.forename: Burcu
authors.initials: B
authors.lastname: Meric
authors.forename: Kagan
authors.initials: K
authors.lastname: Kerman
authors.forename: Stella
authors.initials: S
authors.lastname: Girousi
mesh_terms: D000483:Alleles; D015374:Biosensing Techniques; D004247:DNA / Q000032:analysis / Q000235:genetics; D004252:DNA Mutational Analysis / Q000379:methods*; D004563:Electrochemistry / Q000379:methods*; D005838:Genotype; D006046:Gold / Q000737:chemistry*; D006147:Guanine / Q000737:chemistry*; D009154:Mutation; D049329:Nanostructures / Q000737:chemistry; D010084:Oxidation-Reduction
chemical_list: D006147:Guanine; D006046:Gold; D004247:DNA