CNS regeneration: a morphogen's tale.
Tissue regeneration will soon become an avenue for repair of damaged or diseased tissues as stem cell niches have been found in almost every organ of the vertebrate body including the CNS. In addition, different animals display an array of regenerative capabilities that are currently being researched to dissect the molecular mechanisms involved. This review concentrates on the different ways in which CNS tissues such as brain, spinal cord and retina can regenerate or display neurogenic potential and how these abilities are modulated by morphogens.
Vergara
M Natalia
MN
Department of Zoology, Miami University, Oxford, Ohio 45056, USA. delriok@muohio.edu
Arsenijevic
Yvan
Y
Del Rio-Tsonis
Katia
K
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000502:physiology; D002490:Central Nervous System / Q000502:physiology*; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000502:physiology*; D009416:Nerve Regeneration / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D014212:Tretinoin / Q000502:physiology
D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D047908:Intracellular Signaling Peptides and Proteins; D014212:Tretinoin