title: Hypertrophic lupus erythematosus treated successfully with acitretin as monotherapy.
abstract: Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of chronic cutaneous lupus erythematosus characterized by verrucous lesions which are chronic in course and resistant to treatment (1). We describe the successful use of acitretin in a patient with HLE who had multiple hyperkeratotic verrucous plaques over the dorsa of his hands, feet, and legs and who failed to respond to local steroids and antimalarials.
authors.affiliation: Department of Dermatology, Farwaniya Hospital, State of Kuwait.
authors.forename: Nawaf
authors.initials: N
authors.lastname: Al-Mutairi
authors.forename: Manish
authors.initials: M
authors.lastname: Rijhwani
authors.forename: Osama
authors.initials: O
authors.lastname: Nour-Eldin
mesh_terms: D017255:Acitretin / Q000627:therapeutic use*; D000328:Adult; D001707:Biopsy, Needle; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy / Q000188:drug therapy / Q000473:pathology; D007150:Immunohistochemistry; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin