title: Activating AMP-activated protein kinase without AMP.
abstract: Though once believed to be regulated exclusively by the cellular energy state, AMPK has now been shown to be activated by a calcium-dependent signaling pathway.
authors.affiliation: Howard Hughes Medical Institute and The Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Morris J
authors.initials: MJ
authors.lastname: Birnbaum
mesh_terms: D000091162:AMP-Activated Protein Kinase Kinases; D055372:AMP-Activated Protein Kinases; D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D020013:Calcium Signaling / Q000502:physiology; D054737:Calcium-Calmodulin-Dependent Protein Kinase Kinase; D002490:Central Nervous System / Q000378:metabolism / Q000502:physiology; D004789:Enzyme Activation; D006801:Humans; D008954:Models, Biological; D009097:Multienzyme Complexes / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*
chemical_list: D009097:Multienzyme Complexes; D000249:Adenosine Monophosphate; D017346:Protein Serine-Threonine Kinases; C109790:STK11 protein, human; D054737:Calcium-Calmodulin-Dependent Protein Kinase Kinase; D000091162:AMP-Activated Protein Kinase Kinases; D055372:AMP-Activated Protein Kinases