[Diagnostic role of organ-specific isoforms of lactate dehydrogenase in blood plasma].
Changes in plasm isoenzymic spectrum of lactate dehydrogenase (LDG), a glycolytic enzyme, were studied in death of cardiovascular diseases, ethanol poisoning and a mechanical injury. The tests used electrophoresis in 1% solution of agarose. Isoenzymic composition differed between the groups with acute coronary failure, chronic coronary heart disease, alcohol cardiomyopathy and a mechanical injury. Ethanol poisoning caused two types of characteristic shifts in LDG isoenzymic spectrum. Nomograms were designed for practical application in forensic medical expertise of sudden death.
Vasil'eva
E V
EV
Lopatkin
O N
ON
Kopylov
A V
AV
Morozov
Iu E
IuE
D000208:Acute Disease; D002908:Chronic Disease; D003645:Death, Sudden / Q000473:pathology; D003937:Diagnosis, Differential; D000431:Ethanol / Q000506:poisoning*; D049429:Forensic Pathology; D006331:Heart Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D009928:Organ Specificity; D011041:Poisoning / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D014947:Wounds and Injuries / Q000097:blood / Q000175:diagnosis / Q000473:pathology
D007527:Isoenzymes; D000431:Ethanol; D007770:L-Lactate Dehydrogenase