title: Staphylococcus cohnii as a cause of multiple brain abscesses in Weber-Christian disease.
abstract: We report a patient with multiple brain abscesses due to Staphylococcus cohnii. While these brain abscesses markedly responded to the antibiotics, this patient was subsequently suffered from subcutaneous inflammatory nodules in the adipose tissue, which diagnosed him as having Weber-Christian disease (WCD). This is the first report that subcutaneous inflammatory nodules in the adipose tissue, which lead the diagnosis of WCD, followed multiple brain abscesses. To our knowledge, S. cohnii has not yet been reported to cause multiple brain abscesses in humans. Although the etiology of WCD is unknown, an immune mechanism has been implicated in the pathogenesis. Therefore, we should notice that patients with WCD could be immunocompromised hosts with a higher risk to suffer from severe opportunistic infections.
authors.affiliation: Department of Neurology, Kumamoto Medical Center, National Hospital Organization, 1-5 Ninomaru, Kumamoto 860-0008, Japan. y-stsh@pg8.so-net.ne.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamashita
authors.forename: Kiminobu
authors.initials: K
authors.lastname: Yonemura
authors.forename: Ryoko
authors.initials: R
authors.lastname: Sugimoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Tokunaga
authors.forename: Makoto
authors.initials: M
authors.lastname: Uchino
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging; D001921:Brain / Q000473:pathology; D001922:Brain Abscess / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010201:Panniculitis, Nodular Nonsuppurative / Q000150:complications*; D013203:Staphylococcal Infections / Q000382:microbiology*; D014057:Tomography, X-Ray Computed