title: [Isolated Richter's syndrome in central nervous system: case report].
abstract: Diffuse large cell non Hodgkin's lymphoma associated with chronic lymphoid leukemia (CLL), or Richter's syndrome, is a rare and serious complication. Isolated Richter's syndrome in the central nervous system is very rare; only 12 cases have been reported. We describe a 74-year-old patient with diffuse large cell non Hodgkin's lymphoma in the right frontal region with the appearance of multiform glioblastoma.
authors.affiliation: Clinical Department of Hematology Service, Botucatu Medical School, Sao Paulo State University, Botucatu, Brazil. luan_resende@uol.com.br
authors.forename: Lucilene S R
authors.initials: LS
authors.lastname: Resende
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Bacchi
authors.forename: Luiz Augusto L
authors.initials: LA
authors.lastname: Resende
authors.forename: Roberto Colichio
authors.initials: RC
authors.lastname: Gabarra
authors.forename: Ligia
authors.initials: L
authors.lastname: Niéro-Melo
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005625:Frontal Lobe / Q000473:pathology; D005909:Glioblastoma / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis* / Q000188:drug therapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D013577:Syndrome