title: Primary osteogenic sarcoma of the ethmoid sinus: a case report.
abstract: Primary osteogenic sarcoma arising from the ethmoid sinus is an extremely rare condition. We report herein a 50-year-old female presenting with lacrimation. Computed tomography (CT) scan showed tumor calcification, which is a common feature of osteogenic sarcoma. Exploratory ethmoidectomy was performed, and histological examination confirmed the diagnosis of osteogenic sarcoma. Radiation therapy and chemotherapy failed to reduce the tumor size. The patient was finally treated by anterior craniofacial resection and orbital exenteration. Although primary osteogenic sarcoma of the ethmoid sinus is uncommon, the authors emphasize that osteogenic sarcoma should be suspected when tumor calcification was observed on CT scan and that adequate surgical resection with negative surgical margins remains the mainstay of treatment of this lesion.
authors.affiliation: Department of Otolaryngology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
authors.forename: Rika
authors.initials: R
authors.lastname: Kohanawa
authors.forename: Keiji
authors.initials: K
authors.lastname: Tabuchi
authors.forename: Hideki
authors.initials: H
authors.lastname: Okubo
authors.forename: Michio
authors.initials: M
authors.lastname: Nagata
authors.forename: Akira
authors.initials: A
authors.lastname: Hara
mesh_terms: D005004:Ethmoid Bone / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005005:Ethmoid Sinus / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012516:Osteosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012888:Skull Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D014057:Tomography, X-Ray Computed