Benzothieno and benzofurano annelated estranes.
The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.
Watanabe
Masataka
M
Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Japan.
Mataka
Shuntaro
S
Thiemann
Thies
T
D001391:Azo Compounds / Q000737:chemistry; D001572:Benzofurans / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D004962:Estranes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D001391:Azo Compounds; D001572:Benzofurans; D004962:Estranes; C105430:benzofuran