Asymmetric Carroll rearrangement of allyl alpha-acetamido-beta-ketocarboxylates catalysed by a chiral palladium complex.
Asymmetric decarboxylative rearrangement (Carroll rearrangement) of allyl alpha-acetamido-beta-ketocarboxylates was catalysed by a palladium complex modified with a chiral phosphine ligand, giving optically active gamma,delta-unsaturated alpha-aminoketones with up to 90% ee.
Kuwano
Ryoichi
R
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, Japan.
Ishida
Naoki
N
Murakami
Masahiro
M