[Myelodysplastic syndrome / acute myeloid leukemia with t(8; 21) and bundle of Auer rods in neutrophils: an unusual hemopathy].
We report the case of a 8-year-old girl diagnosed with myelodysplastic syndrome. This case was morphologically characterized by the presence of bundle of Auer rods in the neutrophils. The evolution of the disease was marked by a quick transformation in a acute myeloid leukaemia with t(8;21) refractory to treatment. We reviewed the literature for clinical, biological and therapeutic features of this rare childhood hemopathy.
Kallel
C
C
laboratoire d'hématologie CHU Bourguiba, Sfax, Tunisie. kallelc@viola.fr
Makni
F
F
Bouzidi
H
H
Hdiji
S
S
Elloumi
M
M
Souissi
T
T
Ellouz
F
F
D000208:Acute Disease; D000328:Adult; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D007951:Leukemia, Myeloid / Q000097:blood / Q000235:genetics* / Q000473:pathology; D009190:Myelodysplastic Syndromes / Q000097:blood / Q000235:genetics* / Q000473:pathology; D009504:Neutrophils / Q000473:pathology*; D014178:Translocation, Genetic