title: [Effects of Qilan Tangzhining capsule on glucose and lipid metabolism in rats with diabetes mellitus and hyperlipemia].
abstract: OBJECTIVE
  To study the effects of Qilan Tangzhining capsule on glucose and lipid metabolism in diabetes mellitus and hyperlipemia.
  
  
  METHODS
  Rats were fed with high sugar and fat food for 2 months, then 2% streptozocin (STZ, 30 mg kg(-1)) was injected intraperitoneally to induce hyperglycemia and hyperlipemia. After the model rats were administrated drugs, the blood glucose, the serum lipids, and the histopathology of the liver and pancreas were observed.
  
  
  RESULTS
  Qilan Tangzhining capsule could decrease the FBG and the serum TC, TG, LDL-C, increase HDL-C, and improve the histopathologic injury of the liver and pancreas.
  
  
  CONCLUSIONS
  Qilan Tangzhining capsule can not only adjust the blood glucose and lipid, but also improve the histopathology injury of the liver and pancreas.
authors.affiliation: Beijing University of Chinese Medicine, Beijing 100029, China.
authors.forename: De-qin
authors.initials: DQ
authors.lastname: Zhang
authors.forename: Jian-jun
authors.initials: JJ
authors.lastname: Zhang
authors.forename: Jing-xia
authors.initials: JX
authors.lastname: Wang
authors.forename: Su-min
authors.initials: SM
authors.lastname: Hu
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Li-na
authors.initials: LN
authors.lastname: Ou
authors.forename: Shao-hong
authors.initials: SH
authors.lastname: Chen
authors.forename: Xue-min
authors.initials: XM
authors.lastname: Gao
mesh_terms: D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry; D001786:Blood Glucose / Q000378:metabolism*; D002214:Capsules; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000139:chemically induced / Q000150:complications; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D029774:Gynostemma / Q000737:chemistry; D006949:Hyperlipidemias / Q000097:blood* / Q000150:complications; D008055:Lipids / Q000097:blood*; D008297:Male; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001786:Blood Glucose; D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008055:Lipids