title: Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients.
abstract: The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p<0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70+/-6.0 vs. 82+/-19 beats/min, p<0.01), in W1 (n=11), compared to W0 (n=13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n=8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Chung Shan Medical University, Taichung, Taiwan.
authors.forename: Hua
authors.initials: H
authors.lastname: Ting
authors.forename: Shin-Da
authors.initials: SD
authors.lastname: Lee
authors.forename: Ai-Hui
authors.initials: AH
authors.lastname: Chung
authors.forename: Ming-Lung
authors.initials: ML
authors.lastname: Chuang
authors.forename: Gin-Den
authors.initials: GD
authors.lastname: Chen
authors.forename: Jiuan-Miaw
authors.initials: JM
authors.lastname: Liao
authors.forename: Chen-Lurng
authors.initials: CL
authors.lastname: Chang
authors.forename: Thomas S M
authors.initials: TS
authors.lastname: Chiou
authors.forename: Tzer-Bin
authors.initials: TB
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006945:Hyperhidrosis / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D011659:Pulmonary Gas Exchange / Q000502:physiology; D013562:Sympathectomy / Q000379:methods*; D013997:Time Factors