[Validation of the Brazilian version of mini-test CASI-S].
OBJECTIVE
To determine CASI-S accuracy in the diagnosis of dementia.


METHODS
The Cognitive Abilities Screening Instrument - Short Form (CASI-S) was applied in 43 Alzheimer's disease (AD) patients and 74 normal controls. AD diagnosis was based on DSM-IV, NINCDS-ADRDA, and CAMDEX. CASI-S includes: registration, temporal orientation, verbal fluency (4-legged animals in 30s), and recall (3 words). Its maximum score is 33 points. A copy of 2 pentagons was added.


RESULTS
ROC curve showed an accuracy of 0.87, with standard error of 0.032, and 95% confidence intervall between 0.795 and 0.925. The cut-off score for cognitive deficit was 23, with sensitivity of 76.7%, specificity 86.5%, positive likelihood ratio (LR) 5.68, and negative LR 0.27. The cut-off score for subjects 70 years or older was 20, with sensitivity of 71.4% and specificity 97.1%.


CONCLUSIONS
CASI-S is a practical test, with high specificity, particularly in individuals above 70 years of age. The adding of the drawing test did not improve its accuracy.
Damasceno
Alfredo
A
Unit of Neuropsychology and Neurolinguistics, Department of Neurology, Medical School, State University of Campinas, São Paulo, SP, Brazil. damascen@unicamp.br
Delicio
Adriane M
AM
Mazo
Daniel F C
DF
Zullo
João F D
JF
Scherer
Patricia
P
Ng
Ronny T Y
RT
Damasceno
Benito P
BP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis*; D001938:Brazil; D003072:Cognition Disorders / Q000175:diagnosis*; D004522:Educational Status; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012372:ROC Curve; D012680:Sensitivity and Specificity