Respiratory and general health impairments of workers employed in a municipal solid waste disposal at an open landfill site in Delhi.
The objective of this study was to examine the respiratory and general health of workers employed in a municipal solid waste (MSW) disposal at an open landfill site in India. Ninety-six landfill workers of Okhla landfill site, Delhi, and 90 controls matched for age, sex, and socioeconomic conditions were enrolled. Health data was obtained from questionnaire surveys, clinical examination and laboratory investigations. Lung function was evaluated by spirometry. Compared with matched controls, landfill workers had significantly higher prevalences of both upper and lower respiratory symptoms, and they suffered more often from diarrhea, fungal infection and ulceration of the skin, burning sensation in the extremities, tingling or numbness, transient loss of memory, and depression. Spirometry revealed impairment of lung function in 62% of the landfill workers compared to 27% of the controls. Sputum cytology showed squamous metaplasia, abundance of inflammatory cells, alveolar macrophages (AM) and siderophages (macrophages with iron deposits), and high elastase enzyme activity in neutrophils and AM of a majority of landfill workers, indicating adverse cellular lung reaction. Hematological profiles of these workers depicted low hemoglobin and erythrocyte levels with high total leukocyte, eosinophil and monocyte counts. Erythrocytes with target cell morphology were abundant in 42% of the landfill workers compared to 10% of the controls. Toxic granulation in neutrophils, an indication of infection and inflammation, was recorded in 94% of the landfill workers and in 49% of the controls. The results demonstrated higher prevalence of respiratory symptoms, inflammation of the airways, lung function decrement and a wide range of general health problems in MSW disposal workers.
Ray
Manas Ranjan
MR
Experimental Hematology Unit, Chittaranjan National Cancer Institute, Kolkata, India. manasrray@rediffmail.com
Roychoudhury
Sanghita
S
Mukherjee
Gopeshwar
G
Roy
Senjuti
S
Lahiri
Twisha
T
D000328:Adult; D000395:Air Pollutants, Occupational; D016022:Case-Control Studies; D002947:Cities; D004912:Erythrocytes / Q000473:pathology; D006304:Health Status; D006306:Health Surveys; D006403:Hematologic Tests; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D012037:Refuse Disposal; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000209:etiology*; D013147:Spirometry; D013183:Sputum / Q000166:cytology
D000395:Air Pollutants, Occupational