[Pyogenic spondylitis by methicillin-resistant Staphylococcus aureus (MRSA) during M-VAC therapy: a case report].
We report a case of bacteremic Staphylococcus aureus spondylitis (C6-Thl) during adjuvant M-VAC chemotherapy in a 69-year-old woman. During chemotherapy, low-grade fever persisted and methicillin-resistant Staphylococcus aureus (MRSA) was detected in IVH catheter culture. The patient complained of back pain and numbness of hands; however we kept her under observation. Subsequently sensory disturbance of the lower limbs and total urinary retention were observed. We diagnosed spondylitis by MRI and performed surgical debridement and spinal stabilization. Neurological complications improved after the treatment. The physician should be aware of the possibility of pyogenic spondylitis during chemotherapy.
Danno
Shozo
S
The Department of Urology, Kansai Medical University.
Chizaki
Ryusuke
R
Fukui
Shoichi
S
Matsuda
Tadashi
T
Matsuya
Hiroki
H
Iida
Hirokazu
H
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000601:surgery; D007682:Kidney Pelvis; D008197:Lymph Node Excision; D016106:Methicillin Resistance; D008727:Methotrexate / Q000008:administration & dosage; D009392:Nephrectomy; D011183:Postoperative Complications; D013166:Spondylitis / Q000209:etiology*; D013203:Staphylococcal Infections / Q000209:etiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D001743:Urinary Bladder / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000601:surgery; D014747:Vinblastine / Q000008:administration & dosage
D014747:Vinblastine; D004317:Doxorubicin; D002945:Cisplatin; D008727:Methotrexate