[Effects of Qilan Tangzhining capsule on glucose and lipid metabolism in rats with diabetes mellitus and hyperlipemia].
OBJECTIVE
To study the effects of Qilan Tangzhining capsule on glucose and lipid metabolism in diabetes mellitus and hyperlipemia.


METHODS
Rats were fed with high sugar and fat food for 2 months, then 2% streptozocin (STZ, 30 mg kg(-1)) was injected intraperitoneally to induce hyperglycemia and hyperlipemia. After the model rats were administrated drugs, the blood glucose, the serum lipids, and the histopathology of the liver and pancreas were observed.


RESULTS
Qilan Tangzhining capsule could decrease the FBG and the serum TC, TG, LDL-C, increase HDL-C, and improve the histopathologic injury of the liver and pancreas.


CONCLUSIONS
Qilan Tangzhining capsule can not only adjust the blood glucose and lipid, but also improve the histopathology injury of the liver and pancreas.
Zhang
De-qin
DQ
Beijing University of Chinese Medicine, Beijing 100029, China.
Zhang
Jian-jun
JJ
Wang
Jing-xia
JX
Hu
Su-min
SM
Li
Wei
W
Ou
Li-na
LN
Chen
Shao-hong
SH
Gao
Xue-min
XM
D000818:Animals; D027885:Astragalus propinquus / Q000737:chemistry; D001786:Blood Glucose / Q000378:metabolism*; D002214:Capsules; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000139:chemically induced / Q000150:complications; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D029774:Gynostemma / Q000737:chemistry; D006949:Hyperlipidemias / Q000097:blood* / Q000150:complications; D008055:Lipids / Q000097:blood*; D008297:Male; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008055:Lipids