title: Experimental evaluation of the Corneal Concept 360 intraocular lens with the Miyake-Apple view.
abstract: OBJECTIVE
  To evaluate a new single-piece, hydrophilic acrylic intraocular lens (IOL) designed to keep the anterior capsule away from the IOL optic, create the effect of a capsular tension ring, and prevent posterior capsule opacification (PCO).
  
  
  METHODS
  John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
  
  
  METHODS
  Four Concept 360 IOLs (Corneal Laboratoire) were implanted in 4 human cadaver eyes of various sizes (Miyake-Apple technique). Lens centration, ovalization of the capsular bag and capsulorhexis opening, distance between the anterior optic surface and the anterior capsule and between the posterior optic surface and the posterior capsule, as well as presence of capsular striae were evaluated. The capsular bag was stained with trypan blue, and the ophthalmic viscosurgical device (OVD) was stained with fluorescein to enhance visualization.
  
  
  RESULTS
  In each eye, the lens conformed to the capsular bag with precise centration. No ovalization or distortion of the capsular bag or the capsulorhexis and no posterior capsule striae were observed. Measurements of the capsulorhexis diameter before and after IOL implantation were the same. The anterior capsule remained at distance from the anterior optic surface for 360 degrees, and tight contact between the posterior optic edge and the posterior capsule was observed.
  
  
  CONCLUSIONS
  Use of the Miyake-Apple technique is useful in the evaluation of new IOL designs in experimental studies. Design features of the Concept 360 IOL are likely to decrease the outcome of postoperative capsular bag opacification. Long-term clinical studies are necessary to confirm these findings.
authors.affiliation: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. liliana.werner@hsc.utah.edu
authors.forename: Liliana
authors.initials: L
authors.lastname: Werner
authors.forename: M Scott
authors.initials: MS
authors.lastname: Hickman
authors.forename: Russell M
authors.initials: RM
authors.lastname: LeBoyer
authors.forename: Nick
authors.initials: N
authors.lastname: Mamalis
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D058442:Capsule Opacification / Q000517:prevention & control*; D019923:Capsulorhexis; D005125:Eye Banks; D005260:Female; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007903:Lens Capsule, Crystalline / Q000473:pathology; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011474:Prosthesis Design; D014019:Tissue Donors
chemical_list: D000180:Acrylic Resins