[Cytokine-producing activity of peripheral mononuclear leukocytes in patients with pulmonary tuberculosis before and during chemotherapy].
The paper presents the results of a study of spontaneous and stimulated production of TNF-alpha, INF-gamma, INF-alpha, IL-2 by peripheral mononuclear leukocytes in patients with disseminated destructive drug-resistant pulmonary tuberculosis. It also shows marked changes in the levels the studied cytokines in relation to the type of a stimulant (lipopolysaccharide, phytohemagglutinin, tuberculin) and during antituberculous chemotherapy.
Novitskiĭ
V V
VV
Sinitsyna
V A
VA
Voronkova
O V
OV
Strelis
A K
AK
Urazova
O I
OI
Filiniuk
O V
OV
Zemlianaia
N A
NA
Luk'ianova
T A
TA
Esimova
I E
IE
D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D016207:Cytokines / Q000187:drug effects* / Q000378:metabolism*; D005260:Female; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000187:drug effects* / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology
D000995:Antitubercular Agents; D016207:Cytokines