[Study on direct electrochemical behaviors and the electroanalytical method of matrine type alkaloids at glassy carbon electrode].
OBJECTIVE
To investigate the direct electrochemical behaviors of matrine (MT), oxymatrine (OMT), sophoridine (SR) and oxysophoridine (OSR) at a glassy carbon electrode in a physiological medium, and to determine the contents of commercial MT and SR pharmaceutical products were determined.


METHODS
Their electrochemical behaviors and contents in 0.15 mol x L(-1) NaCl aqueous solutions were obtained by cyclic voltammetry (CV) and square wave voltammetry (SWV) methods.


RESULTS
The electrochemical experimental results show that the two totally irreversible oxidation peaks for both MT and SR were observed, which potential values are 0.81 V and 0.92 V, and the electrode reaction processes were diffusion-controlled. But for both OMT and OSR, they have no oxidation peaks observed in the same condition as well. The linear range of the concentration of MT and SR and the contents in their products were obtained by SWV.


CONCLUSIONS
The research results can be applied in determination of the contents of commercial MT and SR pharmaceutical products.
Yao
Hui-qin
HQ
Key Lab of Energy Sources and Chemical Engineering, College of Chemistry and Chemical Engineering, Ningxia University, Yinchuan 750021, China.
Gao
Zuo-ning
ZN
Han
Xiao-xia
XX
Yu
Jian-qiang
JQ
Du
Yan-ping
YP
D000470:Alkaloids / Q000032:analysis* / Q000737:chemistry; D002244:Carbon; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D010084:Oxidation-Reduction; D010946:Plants, Medicinal / Q000737:chemistry*; D011807:Quinolizines / Q000032:analysis* / Q000737:chemistry; D015203:Reproducibility of Results; D029909:Sophora / Q000737:chemistry*; D000093842:Matrines
D000470:Alkaloids; D011807:Quinolizines; C406983:oxysophoridine; D002244:Carbon; C037573:oxymatrine; D000093842:Matrines