[Dermatomyositis/polymyositis associated with head and neck malignancy].
OBJECTIVE
To observe the relation between dermatomyositis/polymyositis and head-neck malignancy.


METHODS
All 136 cases of dermatomyositis/polymyositis admitted to PUMCH during 10 years (1994-2003) were studied. The clinical features of 6 patients with an associated head-neck malignancy were analyzed.


RESULTS
There were 17 cases of malignancy in 136 patients with dermatomyositis/polymyositis, of which, 6 cases (6/17, 35.29%) were found to have head-neck malignancy: 4 cases of nasopharyngeal carcinoma, 1 case of non-Hodgkin lymphoma and 1 case of hypopharynx carcinoma.


CONCLUSIONS
Nasopharyngeal carcinoma represents the first neoplasm among head-neck malignancy associated with dermatomyositis/polymyositis. Nasal endoscopic and/or fibrolaryngoscopic search for potential head-neck malignancy should be performed in every patient with dermatomyositis/polymyositis.
Liu
Wen
W
Department of Otorhinolaryngology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. liuwen1972@163.com
Gao
Zhiqiang
Z
Ni
Daofeng
D
Li
Wuyi
W
Li
Yulu
Y
Wang
Hui
H
D000328:Adult; D000368:Aged; D003882:Dermatomyositis / Q000150:complications*; D004724:Endoscopy; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000150:complications* / Q000175:diagnosis; D017285:Polymyositis / Q000150:complications*; D012189:Retrospective Studies