Factor Xa inhibitors--a review of the recent patent literature.
This review covers the patent literature and related scientific reports in the field of factor Xa inhibitors published between January 1999 and June 2000. During this time, the amount of scientific information as well as the number of newly published patent applications has continuously increased. It is the aim of this review to give an overview of the different structural types of factor Xa inhibitors, to clarify the relationship between newly claimed and previously known inhibitors, and assess the clinical potential of the different factor Xa inhibitors.
Ries
U J
UJ
Department of Chemical Research, Boehringer Ingelheim Pharma KG, D-88397, Biberach/RiSS, Germany. uwe.ries@bc.boehringer-ingelheim.com
Priepke
H W
HW