title: [Myelodysplastic syndrome / acute myeloid leukemia with t(8; 21) and bundle of Auer rods in neutrophils: an unusual hemopathy].
abstract: We report the case of a 8-year-old girl diagnosed with myelodysplastic syndrome. This case was morphologically characterized by the presence of bundle of Auer rods in the neutrophils. The evolution of the disease was marked by a quick transformation in a acute myeloid leukaemia with t(8;21) refractory to treatment. We reviewed the literature for clinical, biological and therapeutic features of this rare childhood hemopathy.
authors.affiliation: laboratoire d'hématologie CHU Bourguiba, Sfax, Tunisie. kallelc@viola.fr
authors.forename: C
authors.initials: C
authors.lastname: Kallel
authors.forename: F
authors.initials: F
authors.lastname: Makni
authors.forename: H
authors.initials: H
authors.lastname: Bouzidi
authors.forename: S
authors.initials: S
authors.lastname: Hdiji
authors.forename: M
authors.initials: M
authors.lastname: Elloumi
authors.forename: T
authors.initials: T
authors.lastname: Souissi
authors.forename: F
authors.initials: F
authors.lastname: Ellouz
mesh_terms: D000208:Acute Disease; D000328:Adult; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D007951:Leukemia, Myeloid / Q000097:blood / Q000235:genetics* / Q000473:pathology; D009190:Myelodysplastic Syndromes / Q000097:blood / Q000235:genetics* / Q000473:pathology; D009504:Neutrophils / Q000473:pathology*; D014178:Translocation, Genetic