title: The enigma of coproporphyrinogen oxidase: how does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups?
abstract: A new mechanism is proposed to explain how coproporphyrinogen oxidase performs two oxidative decarboxylations on a porphyrinogen substrate without the aid of cofactors or metal ions in the presence of molecular oxygen.
authors.affiliation: Department of Chemistry, Illinois State University, Normal, IL 61790-4160, USA. tdlash@ilstu.edu
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Lash
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry; D003304:Coproporphyrinogen Oxidase / Q000378:metabolism*; D008958:Models, Molecular; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D013379:Substrate Specificity
chemical_list: D002264:Carboxylic Acids; D003304:Coproporphyrinogen Oxidase; D010100:Oxygen