title: The egogram is a potent, independent risk factor for hypertension in pregnancy.
abstract: To assess the association between the egogram and hypertension in pregnancy (HP), a case-control study was carried out. Seventy-one HP cases, primiparous aged 20 to 34 years, and 109 controls, were enrolled among pregnant women who visited our hospitals for obstetrical care. Data from a self-administered questionnaire containing a Self Grow-Up Egogram (SGE) were subjected to univariate and multivariate analyses with prepregnancy body mass index (BMI) and angiotensinogen (AGT) genotype. The mean +/- standard error of total scores for the critical parent (CP) scale were 9.7 +/- 0.5 for cases and 8.3 +/- 0.3 for controls, those for the nurturing parent (NP) scale were 13.6 +/- 0.4 for cases and 13.4 +/- 0.3 for controls, those for the adult (A) scale were 11.3 +/- 0.5 for cases and 10.9 +/- 0.3 for controls, those for the free child (FC) scale were 12.3 +/- 0.3 for cases and 13.8 +/- 0.3 for controls, and those for the adapted child (AC) scale were 10.2 +/- 0.4 for cases and 8.5 +/- 0.4 for controls. A low FC scale score (FC < or = 10) and a high AC scale score (AC > 10) were significantly associated with HP ( p < 0.05; p < 0.01, respectively). In the multivariate analysis, FC < or = 10, AC > 10, prepregnancy BMI > or = 24, and homozygosity of the T235 allele genotype of the AGT gene were detected as the potent independent risk factors for HP. The odds ratios were 2.2, 2.8, 4.0, and 2.5, respectively. The present results suggest that a low FC score and a high AC score may be potent, independent risk factors for HP.
authors.affiliation: Assistant Professor, Hokkaido University School of Medicine, Sapporo, Japan. genkoba@med.hokudai.ac.jp
authors.forename: Gen
authors.initials: G
authors.lastname: Kobashi
authors.forename: Kaori
authors.initials: K
authors.lastname: Ohta
authors.forename: Koichi
authors.initials: K
authors.lastname: Shido
authors.forename: Akira
authors.initials: A
authors.lastname: Hata
authors.forename: Hideto
authors.initials: H
authors.lastname: Yamada
authors.forename: Hisanori
authors.initials: H
authors.lastname: Minakami
authors.forename: Hiko
authors.initials: H
authors.lastname: Tamashiro
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Fujimoto
authors.forename: Kiyotaro
authors.initials: K
authors.lastname: Kondo
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000808:Angiotensinogen / Q000235:genetics; D015992:Body Mass Index; D016022:Case-Control Studies; D004532:Ego; D005260:Female; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000523:psychology*; D016017:Odds Ratio; D010287:Parent-Child Relations; D010552:Personality Assessment; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000209:etiology / Q000523:psychology*; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D000808:Angiotensinogen