title: Signaling and endocytosis: a team effort for cell migration.
abstract: Cellular movement from one place to another is regulated by various guidance cues. The precise perception of these signals in the three-dimensional environment of a multicellular organism is remarkably complex. Recent work is now revealing that guided cell movement also requires spatial control of signaling events by endocytic dynamics.
authors.affiliation: Center for Systems Biology, Department of Medical Genetics and Microbiology, University of Toronto, Canada
authors.forename: Christine
authors.initials: C
authors.lastname: Le Roy
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Wrana
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D034281:Dynamins / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D006801:Humans; D020794:Receptor Protein-Tyrosine Kinases / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D020794:Receptor Protein-Tyrosine Kinases; D034281:Dynamins