On the effects of a chronic deoxynivalenol intoxication on performance, haematological and serum parameters of pigs when diets are offered either for ad libitum consumption or fed restrictively.
Wheat infected naturally with Fusarium, contaminated mainly with deoxynivalenol (DON) (16.6 mg DON/kg), was added to a total constant wheat content of 400 g/kg diet. To distinguish between differences in feed intake and specific effects of the DON contaminated diet, control and DON contaminated feed was administered for 11 weeks under ad libitum and restrictive feeding conditions to 48 pigs of both sexes, which were randomly divided into four groups (n = 12 per group). Feed intake was 2.90 kg/day, live weight gain 987 g/day and feed to gain ratio 2.77 kg/kg for the ad libitum fed control group. The group fed DON contaminated wheat ad libitum significantly consumed 15% less feed and gained 13% less live weight, while the feed to gain ratio was unaffected. Moreover, it was concluded that the lower growth performance by DON contaminated feed resulted mainly from the lower voluntary feed intake, because there were no differences in live weight gain between the groups with the restrictive feeding regimen. On the contrary, metabolizable energy, nitrogen retention digestibility of organic matter, crude protein, crude fat and crude fibre were significantly increased by 3, 10, 3, 6, 9 and 20% in the DON group respectively. Animals fed DON contaminated diets needed more time to consume the restrictive ration than the control group. For example in the first hour after feeding 85% of the control pigs had consumed all feed, but only 39% of the DON group had. There were only few differences in haematological and serum parameters, which were characterized by a high variation between individuals. DON and IgA concentrations in serum were significantly influenced by DON exposure.
Goyarts
T
T
Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Braunschweig, Germany. tanja.goyarts@fal.de
Dänicke
S
S
Rothkötter
H-J
HJ
Spilke
J
J
Tiemann
U
U
Schollenberger
M
M
D000821:Animal Feed / Q000382:microbiology / Q000633:toxicity; D000818:Animals; D005260:Female; D005506:Food Contamination; D005670:Fusarium / Q000737:chemistry / Q000378:metabolism; D008297:Male; D011897:Random Allocation; D013552:Swine / Q000097:blood / Q000502:physiology*; D014255:Trichothecenes / Q000378:metabolism / Q000633:toxicity*; D014908:Triticum / Q000737:chemistry* / Q000382:microbiology*; D015430:Weight Gain
D014255:Trichothecenes; C007262:deoxynivalenol