A QSAR review on melanoma toxicity.
Melanoma is one of the most aggressive forms of skin cancer and is currently attracting our attention particularly in the area of quantitative structure-activity relationships (QSAR). In the present review, an attempt has been made to collect the data for different sets of compounds and to discuss their toxicities toward melanoma cells by the formulation of a total number of 36 QSAR.
Verma
Rajeshwar P
RP
Department of Chemistry, Pomona College, Claremont, CA 91711, USA.
Mekapati
Suresh B
SB
Kurup
Alka
A
Hansch
Corwin
C
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008545:Melanoma / Q000188:drug therapy* / Q000378:metabolism*; D015394:Molecular Structure; D009930:Organic Chemicals / Q000494:pharmacology*; D021281:Quantitative Structure-Activity Relationship
D009930:Organic Chemicals