title: [Influence of basic fibroblast growth factors on the migration, proiferation of osteoblasts and periodontal ligament fibroblasts].
abstract: OBJECTIVE
  In order to determine the influence of bFGF on the biological characteristics of osteoblasts and periodontal ligament cells, the author investigate the influence of bFGF on the migration, proliferation of osteoblasts and periodontal ligament fibroblasts between osteoblasts and fibroblasts.
  
  
  METHODS
  The forth generation of osteoblasts and periodontal ligament fibroblast were obtained and the wounding model in vitro of them was founded. The cells were cultured in mediums with or without bFGF. Their migration and proliferation were observed and measured.
  
  
  RESULTS
  Osteoblasts migrated faster than fibroblasts in common culture medium without bFGF and the periodontal ligament fibroblasts in culture medium with bFGF had higher migration rate than other groups. bFGF promoted the proliferation of both two kinds of cells.
  
  
  CONCLUSIONS
  bFGF could accelerate periodontal fibroblasts' proliferation and migration.
authors.affiliation: Key Laboratory of Oral Biomedical Engineering Ministry of Education, Sichuan University, Chengdu 610041, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Tan
authors.forename: Ping
authors.initials: P
authors.lastname: Gong
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhao
mesh_terms: D049109:Cell Proliferation; D002478:Cells, Cultured; D016222:Fibroblast Growth Factor 2; D005347:Fibroblasts; D010006:Osteoblasts; D010513:Periodontal Ligament
chemical_list: D016222:Fibroblast Growth Factor 2