title: [Usefulness of branched-chain amino acid (BCAA)-enriched nutrient mixture for nutritional treatment undergoing endoscopic treatment for esophageal varices].
abstract: We investigated the alteration of nutritional status in 144 patients who were treated for the first time with endoscopic sclerotherapy or endoscopic variceal ligation during their therapies. The serum levels of albumin, cholinesterase and total cholesterol were compared before and after treatment. The serum level of cholinesterase declined significantly. To investigate the impact of aging on the changes of nutritional status we divided all patients into two groups: (1) under 65 years, and (2) over 65 years. The decline of serum albumin of elderly patients (n=65) was significantly greater than that of younger patients (n=79). A branched-chain amino acid (BCAA)-enriched nutrient mixture for nutritional treatment significantly suppressed the decline of serum albumin in elderly patients. Nutritional treatment with a BCAA-enriched nutrient mixture should be considered during endoscopic therapy for esophageal varices, especially in elderly patients.
authors.affiliation: The Third Department of Internal Medicine, Ehime University School of Medicine.
authors.forename: Naozumi
authors.initials: N
authors.lastname: Shibata
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Matsui
authors.forename: Eiji
authors.initials: E
authors.lastname: Takeshita
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yokota
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Higaki
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Murakami
authors.forename: Yoshiou
authors.initials: Y
authors.lastname: Ikeda
authors.forename: Hisaka
authors.initials: H
authors.lastname: Minami
authors.forename: Bunzo
authors.initials: B
authors.lastname: Matsuura
authors.forename: Morikazu
authors.initials: M
authors.lastname: Onji
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage*; D002784:Cholesterol / Q000097:blood; D002802:Cholinesterases / Q000097:blood; D004932:Esophageal and Gastric Varices / Q000378:metabolism / Q000628:therapy*; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D015911:Sclerotherapy; D012709:Serum Albumin / Q000032:analysis
chemical_list: D000597:Amino Acids, Branched-Chain; D012709:Serum Albumin; D002784:Cholesterol; D002802:Cholinesterases