title: Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis.
abstract: Quality Control is a fundamental aspect of successful microarray data analysis. Simpleaffy is a BioConductor package that provides access to a variety of QC metrics for assessing the quality of RNA samples and of the intermediate stages of sample preparation and hybridization. Simpleaffy also offers fast implementations of popular algorithms for generating expression summaries and detection calls.
  
  
  BACKGROUND
  Simpleaffy can be downloaded from http://www.bioconductor.org.
  
  
  BACKGROUND
  Additional information can be found on the supplementary website located at http://bioinformatics.picr.man.ac.uk.
authors.affiliation: Paterson Institute for Cancer Research, Manchester M20 4BX, UK.
authors.forename: Claire L
authors.initials: CL
authors.lastname: Wilson
authors.forename: Crispin J
authors.initials: CJ
authors.lastname: Miller
mesh_terms: D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D003198:Computer Simulation; D003628:Database Management Systems; D020869:Gene Expression Profiling; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods*; D011786:Quality Control; D012313:RNA / Q000737:chemistry; D017422:Sequence Analysis, DNA; D012984:Software; D013223:Statistics as Topic / Q000379:methods; D014584:User-Computer Interface
chemical_list: D012313:RNA