Prevalence and severity of liver disease in patients with b thalassemia major. A single-institution fifteen-year experience.
During the last years, liver disease has emerged as a major cause of mortality in patients with b thalassemia major (TM). In spite of its clinical relevance, TM-associated liver damage has been insufficiently characterized. We therefore retrospectively analyzed all TM patients of our Department who underwent liver biopsy since 1990.
Perifanis
Vassilios
V
Tziomalos
Konstantinos
K
Tsatra
Ioanna
I
Karyda
Stavroula
S
Patsiaoura
Kalliopi
K
Athanassiou-Metaxa
Miranda
M
D005091:Exons; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics*; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology / Q000235:genetics / Q000503:physiopathology*; D009154:Mutation; D015995:Prevalence; D015183:Restriction Mapping; D012189:Retrospective Studies; D017086:beta-Thalassemia / Q000150:complications* / Q000235:genetics
D005954:Glucosephosphate Dehydrogenase