title: Trends of HIV-1 seroincidence among HIV-1 sentinel surveillance groups in Cambodia, 1999-2002.
abstract: This study reports trends in HIV-1 incidence in Cambodia among different target groups in the HIV-1 Sentinel Surveillance Program in 1999, 2000, and 2002, using the newly developed IgG capture BED-enzyme (HIV subtypes B, E and D) immunoassay (BED-CEIA). HIV-1-positive specimens (n=3599) from 4 sentinel groups in the HIV-1 Sentinel Surveillance Program from 1999 to 2002-brothel-based commercial sex workers (CSWs), indirect commercial sex workers (IDSWs), police, and women attending antenatal clinics (ANCs)-were tested using the BED-CEIA. Annualized incidence rates were calculated for each group and each geographic region. Between 1999 and 2002, incidence rates declined among CSWs from 13.9% to 6.45%, among IDSWs from 5.92% to 2.87%, and among police from 1.58% to 0.26%. In the ANC group, the incidence remained stable, 0.64% in 1999, 1.11% in 2000, and 0.59% in 2002. However, there was an increasing trend among ANCs in rural areas, from 0.12 to 0.89%. In conclusion, HIV-1 incidence among CSWs, IDSWs, and police has declined between 1999 and 2002; however, the incidence has not declined in the ANC group.
authors.affiliation: National Center for HIV/AIDS, Dermatology and STDs, Phnom Penh, Cambodia and the Department of Epidemiology, University of California School of Public Health, Los Angeles, CA 90095-1772, USA.
authors.forename: Vonthanak
authors.initials: V
authors.lastname: Saphonn
authors.forename: Bharat S
authors.initials: BS
authors.lastname: Parekh
authors.forename: Trudy
authors.initials: T
authors.lastname: Dobbs
authors.forename: ChiVun
authors.initials: C
authors.lastname: Mean
authors.forename: Leng Hor
authors.initials: LH
authors.lastname: Bun
authors.forename: Sun Penh
authors.initials: SP
authors.lastname: Ly
authors.forename: Sopheab
authors.initials: S
authors.lastname: Heng
authors.forename: Roger
authors.initials: R
authors.lastname: Detels
mesh_terms: D000293:Adolescent; D000328:Adult; D002160:Cambodia / Q000453:epidemiology; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016495:Police; D011247:Pregnancy; D018571:Sentinel Surveillance; D011477:Sex Work