title: [The effect of tofisopam and tinctura leonuri on the color-discrimination function in young humans].
abstract: Enhanced anxiety state is accompanied by limitation of the color-discrimination function of retina in young humans. Chronic administration of tofisopam (grandaxin) or tinctura leonuri decreased anxiety and significantly improved the color discrimination function of retina with respect to all four colors studied. It is suggested that this improvement is related to the drug action upon the GABAergic processes both in the retina and in the related cerebral structures.
authors.forename: K B
authors.initials: KB
authors.lastname: Ovanesov
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001007:Anxiety / Q000503:physiopathology*; D001569:Benzodiazepines / Q000494:pharmacology*; D003118:Color Perception / Q000187:drug effects*; D005260:Female; D006801:Humans; D031332:Leonurus / Q000737:chemistry*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D012160:Retina / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D014151:Anti-Anxiety Agents; D010936:Plant Extracts; D001569:Benzodiazepines; C012582:tofisopam