Hypertrophic lupus erythematosus treated successfully with acitretin as monotherapy.
Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of chronic cutaneous lupus erythematosus characterized by verrucous lesions which are chronic in course and resistant to treatment (1). We describe the successful use of acitretin in a patient with HLE who had multiple hyperkeratotic verrucous plaques over the dorsa of his hands, feet, and legs and who failed to respond to local steroids and antimalarials.
Al-Mutairi
Nawaf
N
Department of Dermatology, Farwaniya Hospital, State of Kuwait.
Rijhwani
Manish
M
Nour-Eldin
Osama
O
D017255:Acitretin / Q000627:therapeutic use*; D000328:Adult; D001707:Biopsy, Needle; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy / Q000188:drug therapy / Q000473:pathology; D007150:Immunohistochemistry; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D012720:Severity of Illness Index; D016896:Treatment Outcome
D007641:Keratolytic Agents; D017255:Acitretin