title: A case of severe Pierre Robin sequence with failure to thrive and tachycardia resolved after redo-fundoplication and hiatoplasty.
abstract: We report an infant suffering from Pierre Robin sequence complicated by gastro-oesophageal reflux and failure to thrive, which were resistant to conservative therapy and a hemifundoplication. Gastro-oesophageal reflux was accompanied by supraventricular tachycardia, treated with propafenone. Tachycardia may be present in Pierre Robin sequence as a consequence of cardiac parasympathetic imbalance. The patient recovered completely from the gastro-oesophageal reflux and tachycardia after redo-fundoplication (Nissen) and a hiatoplasty were performed.
  
  
  CONCLUSIONS
  This case shows that a thorough search for gastro-oesophageal reflux is indicated in each case of Pierre Robin sequence with failure to thrive.
authors.affiliation: Chirurgische Universitätsklinik, Fakultät für Klinische Medizin Mannheim der Universität Heidelberg, Mannheim, Germany .
authors.forename: Konrad
authors.initials: K
authors.lastname: Reinshagen
authors.forename: Jörn
authors.initials: J
authors.lastname: Schellscheidt
authors.forename: Klaus-Peter
authors.initials: KP
authors.lastname: Zimmer
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D005183:Failure to Thrive / Q000150:complications / Q000209:etiology* / Q000601:surgery; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000150:complications / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007228:Infant Nutrition Disorders / Q000209:etiology / Q000601:surgery; D010855:Pierre Robin Syndrome / Q000150:complications / Q000601:surgery*; D012086:Reoperation; D012720:Severity of Illness Index; D013617:Tachycardia, Supraventricular / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D000889:Anti-Arrhythmia Agents