title: No evidence of plasticity in hair follicles of recipients after allogeneic hematopoietic stem cell transplantation.
abstract: Here we show in a prospective quantitative study of 115 patients after allogeneic hematopoietic stem cell transplantation that hair follicles remain exclusively of recipient type despite full whole blood donor-type chimerism. Our data indicate that unmanipulated hematopoietic donor stem cells do not contribute directly to reconstitution even in an organ at highest need for repair.
authors.affiliation: Division of Hematology, University Hospital Basel, Basel, Switzerland. aliciarovo@bluewin.ch
authors.forename: Alicia
authors.initials: A
authors.lastname: Rovó
authors.forename: Sandrine
authors.initials: S
authors.lastname: Meyer-Monard
authors.forename: Dominik
authors.initials: D
authors.lastname: Heim
authors.forename: Caroline
authors.initials: C
authors.lastname: Arber
authors.forename: Jakob R
authors.initials: JR
authors.lastname: Passweg
authors.forename: Alois
authors.initials: A
authors.lastname: Gratwohl
authors.forename: André
authors.initials: A
authors.lastname: Tichelli
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D018859:Hair Follicle / Q000166:cytology / Q000502:physiology*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012038:Regeneration / Q000502:physiology*; D018183:Transplantation Chimera / Q000502:physiology*