title: Radio-guided localization of clinically occult breast lesions (ROLL): a DGH experience.
abstract: OBJECTIVE
  Wire-guided localization (WGL) of clinically occult breast lesions is a well established technique. The aim of this study was to evaluate radio-guided localization (ROLL) within the breast screening service of a district general hospital.
  
  
  METHODS
  The study group comprised 70 women who underwent ROLL under US and stereotaxis. This required an injection of Technetium-labelled colloidal albumen into the impalpable breast lesion. The women then proceeded to theatre, where localization was achieved with the use of a gamma probe. The lesion was identified by the presence of a high signal, caused by the injected isotope. The results of 70 consecutive cases in which a breast lesion was localized using ROLL were compared with the results of the latest 70 WGLs.
  
  
  RESULTS
  All 140 lesions were successfully localized. However, the change in technique from WGL to ROLL offered significant benefits to patients.
  
  
  CONCLUSIONS
  Our study demonstrated that ROLL is a practical and reliable localization technique. It can be implemented in hospital units without using valuable gamma camera time. The cost compares well with WGL. There is an improved cosmetic outcome for patients, and the very small quantity of radioactivity used is safe for both patients and staff.
authors.affiliation: St Helens and Knowsley Hospitals, Prescot, UK. thindr@aol.com
authors.forename: C R
authors.initials: CR
authors.lastname: Thind
authors.forename: S
authors.initials: S
authors.lastname: Desmond
authors.forename: O
authors.initials: O
authors.lastname: Harris
authors.forename: R
authors.initials: R
authors.lastname: Nadeem
authors.forename: L S
authors.initials: LS
authors.lastname: Chagla
authors.forename: R A
authors.initials: RA
authors.lastname: Audisio
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D005240:Feasibility Studies; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D013668:Technetium Tc 99m Aggregated Albumin; D014463:Ultrasonography
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin