Regulatory oversight of the iron trade: posttranscriptional regulation in yeast.
Though a required element, iron is toxic in high concentration. New evidence reveals pathways for controlling the abundance of mRNAs encoded by iron utilization and distribution genes. These studies demonstrate sophisticated systems that limit iron uptake under conditions of abundance and lead to metabolic remodeling when iron is limited.
Kaplan
Craig D
CD
Department of Structural Biology, Stanford University, Palo Alto, CA 94305, USA.
Kaplan
Jerry
J
D015966:Gene Expression Regulation, Fungal; D007501:Iron / Q000378:metabolism*; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism*
D007501:Iron