title: [Study on preparation of refined Xiong-gui sustained release pills].
abstract: OBJECTIVE
  To optimize the molding formula of refined Xiong-gui sustained release pills, types and assorted dosages of water-soluble and non water-soluble drug carrier were studied.
  
  
  METHODS
  An orthogonal design was performed to sift the pill formulation. The processing conditions were determining in terms of roundness, hardness, viscosity, fluidity, easily drop.
  
  
  CONCLUSIONS
  According to the final optimal formula, the amount of drug release can be detected instantly, while remaining over 80% at 10 h.
authors.affiliation: Institute of Chinese Material Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China. lihuiyiren@sina.com
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Bao-lin
authors.initials: BL
authors.lastname: Bian
authors.forename: Fan-yun
authors.initials: FY
authors.lastname: Meng
authors.forename: Yi-tao
authors.initials: YT
authors.lastname: Wang
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000032:analysis; D029971:Angelica sinensis / Q000737:chemistry*; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000737:chemistry / Q000302:isolation & purification; D030004:Ligusticum / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D003692:Delayed-Action Preparations; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C027820:ligustilide; D015107:4-Butyrolactone