title: Polymorphism of doxazosin mesylate.
abstract: Nine polymorphic modifications of doxazosin mesylate have been obtained by recrystallization in organic solvents under variable conditions. Different polymorphs of doxazosin mesylate were characterized by powder X-ray crystallography diffractometry (PXRD), differential scanning calorimetry (DSC), and thermogravimetric analysis (TG). Transformation of Form 1 and Form 2 was not occurred in three relative humidities (0%, 51%, and 99%) at 20 +/- 0.5 for 30 days.
authors.affiliation: Young-Taek Sohn, College of Pharmacy, Duksung Women's University, 419 Ssangmun-Dong, Dobong-Gu, 132-714 Seoul, Korea. ytsohn@duksung.ac.kr
authors.forename: Young-Taek
authors.initials: YT
authors.lastname: Sohn
authors.forename: Yoon-Hee
authors.initials: YH
authors.lastname: Lee
mesh_terms: D002152:Calorimetry, Differential Scanning; D003460:Crystallization; D018360:Crystallography, X-Ray; D017292:Doxazosin / Q000737:chemistry*; D015394:Molecular Structure; D013818:Thermogravimetry
chemical_list: D017292:Doxazosin