title: [Results of a morphological study of the experimental use of polyglycolide fiber explants in the surgery of retinal detachment].
abstract: The paper presents the results of experimental use of a polyglycolide material-based filling for temporary episcleral filling in retinal detachment. Thorough comparative morphological and biomechanical studies of 120 experimental eyes in different periods after scleroplasty, by using an inflatable balloon catheter, homoscleral and polyglycolide fillings, have indicated that the polyglycolide filling material is completely lysed by ocular tissues within 60-90 days, which rules out a repeated surgical intervention for removal of temporary filling (for example, an inflatable balloon catheter), by preserving the constancy of the depth of scleral pressing-in. The short existence of a chemically indifferent polyglycolide filling in the ocular tissues excludes its negative effect on the surrounding structures of the eye, minimizes the likelihood of the occurrence of early postoperative complications, but thereby leading to a substantial increase in the biochemical stability of the scleral-and-chorioretinal complex in the early postoperative periods and ensuring increased resistance to dynamic loads, by forming a stable scleral-and-chorioretinal adhesion 3 months after surgery. The findings suggest that the designed polyglycolide explant has advantages and that it is expedient to introduce the new Russian resolving polyglycolide fiber explants into clinical practice (for scleroplastic operations).
authors.forename: O A
authors.initials: OA
authors.lastname: Kiseleva
authors.forename: G G
authors.initials: GG
authors.lastname: Ziangirova
authors.forename: E N
authors.initials: EN
authors.lastname: Iomdina
authors.forename: T I
authors.initials: TI
authors.lastname: Aliev
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D004195:Disease Models, Animal; D005500:Follow-Up Studies; D011100:Polyglycolic Acid; D011183:Postoperative Complications / Q000517:prevention & control; D011817:Rabbits; D015203:Reproducibility of Results; D012163:Retinal Detachment / Q000473:pathology / Q000601:surgery*; D012591:Scleral Buckling / Q000295:instrumentation*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D011100:Polyglycolic Acid