title: Investigation of vacuum pumping on the dose response of the MAGAS normoxic polymer gel dosimeter.
abstract: The effect of vacuum pumping on the dose response of the MAGAS polymer gel dosimeter has been investigated. A delay of several days post-manufacture before irradiation was previously necessary due to the slow oxygen scavenging of ascorbic acid. The MAGAS polymer gel dosimeter was vacuum pumped before gelation to remove dissolved oxygen. The MAGAS polymer gel dosimeter was poured into glass screw-top vials, which were irradiated at various times, post-manufacture to a range of doses. Magnetic resonance imaging techniques were used to determine the R2-dose response and R2-dose sensitivity of the MAGAS polymer gel. The results were compared with a control batch of MAGAS polymer gel that was not vacuum pumped. It was shown that vacuum pumping on the MAGAS polymer gel solution immediately prior to sealing in glass screw-top vials initially increases the R2-dose response and R2-dose sensitivity of the dosimeter. An increase in the R2-dose response and R2-dose sensitivity was observed with increasing time between manufacture and irradiation. Over the range of post-manufacture irradiation times investigated, the greatest R2-dose response and R2-dose sensitivity occurred at 96 hours.
authors.affiliation: School of Physical and Chemical Sciences, Queensland University of Technology, Brisbane, Australia.
authors.forename: A J
authors.initials: AJ
authors.lastname: Venning
authors.forename: M L
authors.initials: ML
authors.lastname: Mather
authors.forename: C
authors.initials: C
authors.lastname: Baldock
mesh_terms: D004307:Dose-Response Relationship, Radiation; D019544:Equipment Failure Analysis; D005782:Gels / Q000737:chemistry / Q000528:radiation effects; D008689:Methacrylates / Q000737:chemistry* / Q000528:radiation effects*; D010100:Oxygen / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry / Q000528:radiation effects; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014618:Vacuum
chemical_list: D005782:Gels; D008689:Methacrylates; D011108:Polymers; C008384:methacrylic acid; D010100:Oxygen