title: Conformational diastereoisomerism in a chiral pretzelane.
abstract: The introduction of a stereogenic center by a stereospecific synthesis into an optically active, donor-acceptor pretzelane, that exhibits helicity as well as fixed chirality, leads to a marked preference for one conformational diastereoisomer over the other in both acetone and dimethylsulfoxide that can be understood from computational models.
authors.affiliation: California NanoSystems Institute and the Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, CA 90095, USA.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Scott A
authors.initials: SA
authors.lastname: Vignon
authors.forename: Xiyun
authors.initials: X
authors.lastname: Zhang
authors.forename: K N
authors.initials: KN
authors.lastname: Houk
authors.forename: J Fraser
authors.initials: JF
authors.lastname: Stoddart