In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers.
Nesterov
Evgueni E
EE
Department of Chemistry and Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Skoch
Jesse
J
Hyman
Bradley T
BT
Klunk
William E
WE
Bacskai
Brian J
BJ
Swager
Timothy M
TM
D000544:Alzheimer Disease / Q000175:diagnosis*; D000682:Amyloid / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D003952:Diagnostic Imaging / Q000379:methods; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D051379:Mice; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D013050:Spectrometry, Fluorescence; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics
D000682:Amyloid; D005456:Fluorescent Dyes; C514194:NIAD-4 dye; D009570:Nitriles; D013876:Thiophenes