title: Catalytic enantioselective Diels-Alder reaction by self-assembly of the components on a Lewis acid template.
abstract: Thermal Diels-Alder reaction of 2,4-hexadienol with methyl acrylate is unselective. By simultaneous coordination of diene and dienophile to a chiral bimetallic Lewis acid catalyst, a LACASA-DA reaction occurs with complete control of regio-, diastereo-, and enantioselectivity to give a single adduct. [reaction: see text]
authors.affiliation: Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK, S7N 5C9 Canada. Dale.Ward@usask.ca
authors.forename: Dale E
authors.initials: DE
authors.lastname: Ward
authors.forename: Michael Santos
authors.initials: MS
authors.lastname: Souweha