The "zoom lens" of focal attention in visual search: changes in aging and Alzheimer's disease.
Visual search for a target in an array of distractors relies upon flexible shifts between global and local modes of attentional processing. Visual search is slowed in patients with Alzheimer's disease (AD), in part due to an increase in the number and duration of eye fixations made en route to a target (Rösler et al., 2000). This phenomenon may represent a compensatory adaptation to a narrowing of the zone of focal attention, necessitating more shifts of gaze in order to attend to the global workspace. Eye fixations were analyzed in two regions of interest (ROIs, central fixation and peripheral target locations) in 9 patients with mild AD, 9 cognitively intact age-matched control subjects, and 9 young controls, while they searched for a target object in a radial array that contained from 1 to 6 stimuli. Contrasted with young subjects, the search strategy of older controls and, to a greater extent, AD patients showed an increase in the average number and duration of peripheral fixations. Reduced efficiency of visual search in AD may be contributed to by reduced ability to dynamically adjust the attentional zoom, coupled with the inability to disengage attention from peripheral targets.
Rösler
Alexander
A
Cognitives Neurology and Alzheimer's Disease Center, Northwestern University Medical School, Chicago, IL, USA. Alexander.Roesler@kgu.de
Mapstone
Mark
M
Hays-Wicklund
Alissa
A
Gitelman
Darren R
DR
Weintraub
Sandra
S
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D000544:Alzheimer Disease / Q000503:physiopathology*; D001288:Attention / Q000502:physiology*; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology; D006801:Humans; D008297:Male; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*