title: Antimicrobial activity of isopteropodine.
abstract: Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.
authors.affiliation: Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile. rgarciam@uchile.cl
authors.forename: Rubén
authors.initials: R
authors.lastname: García
authors.forename: Cesia
authors.initials: C
authors.lastname: Cayunao
authors.forename: Ronny
authors.initials: R
authors.lastname: Bocic
authors.forename: Nadine
authors.initials: N
authors.lastname: Backhouse
authors.forename: Carle
authors.initials: C
authors.lastname: Delporte
authors.forename: Mercedes
authors.initials: M
authors.lastname: Zaldivar
authors.forename: Silvia
authors.initials: S
authors.lastname: Erazo
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts; D018547:Plant Stems / Q000737:chemistry; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D032070:Uncaria / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts