Activity of disaccharidases in arctic populations: evolutionary aspects disaccharidases in arctic populations.
Disorders of dietary sugar assimilation occur more often among native people of the Arctic then in temperate climate inhabitants. It is hypothesized that the limited variety of natural exogenous sugars in the Arctic, and their low content in the traditional diets of native northerners in accordance with a "protein-lipid" type of metabolism weakened selection, favoring diversity of disaccharidase enzymes.
Kozlov
Andrew
A
Institute of Developmental Physiology, Russian Academy of Education, Moscow, Russia. aikozlov@narod.ru
Vershubsky
Galina
G
Borinskaya
Svetlana
S
Sokolova
Maria
M
Nuvano
Vladislav
V
D000222:Adaptation, Physiological; D000367:Age Factors; D001110:Arctic Regions / Q000453:epidemiology; D005075:Biological Evolution; D001786:Blood Glucose; D002239:Carbohydrate Metabolism, Inborn Errors / Q000201:enzymology* / Q000453:epidemiology*; D004032:Diet; D004186:Disaccharidases / Q000172:deficiency / Q000378:metabolism*; D005006:Ethnicity / Q000706:statistics & numerical data; D006801:Humans
D001786:Blood Glucose; D004186:Disaccharidases