The effect of the range of interaction on the phase diagram of a globular protein.
Thermodynamic perturbation theory is applied to the model of globular proteins studied by ten Wolde and Frenkel [P. R. ten Wolde and D. Frenkel Science 77, 1975 (1997)] using computer simulation. It is found that the reported phase diagrams are accurately reproduced. The calculations show how the phase diagram can be tuned as a function of the length scale of the potential.
Lutsko
James F
JF
Center for Nonlinear Phenomena and Complex Systems, Université Libre de Bruxelles, Belgium. jlutsko@ulb.ac.be
Nicolis
Grégoire
G
D000465:Algorithms; D003198:Computer Simulation; D005914:Globins / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry; D017510:Protein Folding; D013816:Thermodynamics
D010455:Peptides; D005914:Globins