title: Bowen disease of the eyelid successfully treated with imiquimod.
abstract: We present a case of Bowen disease affecting the eyelid that was successfully treated with imiquimod. The clinical presentation, histopathology, and treatment of this case are presented. The tumor was treated with imiquimod for 3 months, leading to complete resolution of the disease both clinically and histopathologically. There was no evidence of recurrence 5 months after treatment cessation. Imiquimod was safely used on the eyelid in this case and may avoid extensive periocular tumor excision and reconstruction in Bowen disease.
authors.affiliation: University of Cincinnati, Department of Ophthalmology, Cincinnati Eye Institute, Ohio 45242, USA. paulbrannan@hotmail.com
authors.forename: Paul A
authors.initials: PA
authors.lastname: Brannan
authors.forename: Heidi K
authors.initials: HK
authors.lastname: Anderson
authors.forename: Robert C
authors.initials: RC
authors.lastname: Kersten
authors.forename: Dwight R
authors.initials: DR
authors.lastname: Kulwin
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001913:Bowen's Disease / Q000188:drug therapy* / Q000473:pathology; D005142:Eyelid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D008297:Male; D009824:Ointments; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D009824:Ointments; D000077271:Imiquimod