title: Effects of high intensity resistance training on arterial stiffness and wave reflection in women.
abstract: BACKGROUND
  Cross-sectional studies reported that chronic resistance training is associated with arterial stiffening in men. These findings are in marked contrast to those found with aerobic exercise and may have important clinical relevance with regard to cardiovascular disease risk. However, the effect of resistance training on arterial stiffness has not been confirmed by interventional studies nor has this relation been investigated in women.
  
  
  METHODS
  To determine whether a strength training program increases regional and central arterial stiffness in women, 23 healthy young women (29+/-1 years; mean+/-SD) participated in a high-intensity strength and power training program for 11 weeks. Ten other women (27+/-2 years) served as time controls.
  
  
  RESULTS
  In the intervention group, one repetition maximal strength increased 12% to 17% (P<.0001), and leg fat-free mass (via DEXA) increased significantly. Brachial blood pressure (BP) and fasting plasma lipid and lipoprotein concentrations did not change across the 11 weeks. Carotid augmentation index, a measure of arterial wave reflection and arterial stiffness, increased from -8%+/-13% to 1%+/-18% (P<.05), and carotid-femoral pulse wave velocity increased (791+/-88 v 833+/-96 cm/sec; P<.05). There were no changes in femoral-ankle pulse wave velocity, a segmental measure of peripheral arterial stiffness.
  
  
  CONCLUSIONS
  We concluded that a high-intensity resistance training program increases arterial stiffness and wave reflection in young healthy women. Our present interventional results are consistent with the previous cross-sectional studies in men in which high-intensity strength training is associated with arterial stiffening.
authors.affiliation: Department of Kinesiology and Health Education, University of Texas at Austin, Austin, Texas, USA.
authors.forename: Miriam Y
authors.initials: MY
authors.lastname: Cortez-Cooper
authors.forename: Allison E
authors.initials: AE
authors.lastname: DeVan
authors.forename: Maria M
authors.initials: MM
authors.lastname: Anton
authors.forename: Roger P
authors.initials: RP
authors.lastname: Farrar
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Beckwith
authors.forename: Janice S
authors.initials: JS
authors.lastname: Todd
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001158:Arteries / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D001823:Body Composition / Q000502:physiology; D015992:Body Mass Index; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D018482:Muscle, Skeletal / Q000502:physiology; D010701:Phonocardiography; D010809:Physical Fitness / Q000502:physiology*; D014891:Weight Lifting / Q000502:physiology*
chemical_list: D008055:Lipids; D008074:Lipoproteins