title: Reliability of individual functional MRI brain mapping of language.
abstract: The use of individual brain mapping for a single case study implicitly assumes that the pattern of activation obtained in a single session represents the subject's functional neuroanatomy. It is therefore essential to estimate the potential variability of brain activation in individuals. To this purpose, the authors compared the pattern of activation determined by statistical parametric mapping (SPM 99) in 9 subjects who repeated 3 verbal tasks in 3 separate sessions. In each subject for each task, the authors examined the intersession variability of the volume of activation in a set of regions classically implicated in language processing. Their results show that reproducibility of functional MRI brain mapping for language within subject varies as a function of the activation task and the region of interest for language.
authors.affiliation: Laboratoire de Neuroimagerie in Vivo, Faculté de Médecine, Unité Mixte de Recherche, Strasbourg, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Otzenberger
authors.forename: Daniel
authors.initials: D
authors.lastname: Gounot
authors.forename: Corinne
authors.initials: C
authors.lastname: Marrer
authors.forename: Izzie Jacques
authors.initials: IJ
authors.lastname: Namer
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: Metz-Lutz
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007802:Language; D007807:Language Tests; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D014706:Verbal Learning