Antimicrobial activity of isopteropodine.
Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.
García
Rubén
R
Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile. rgarciam@uchile.cl
Cayunao
Cesia
C
Bocic
Ronny
R
Backhouse
Nadine
N
Delporte
Carle
C
Zaldivar
Mercedes
M
Erazo
Silvia
S
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts; D018547:Plant Stems / Q000737:chemistry; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D032070:Uncaria / Q000737:chemistry*
D000890:Anti-Infective Agents; D010936:Plant Extracts