title: Comparison of a 1,064 nm laser and a 1,320 nm laser for the nonablative treatment of acne scars.
abstract: BACKGROUND
  There have been many reports of the use of nonablative lasers for the treatment of acne scars.
  
  
  OBJECTIVE
  To evaluate the ability of the 1,064 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser to treat acne scars and compare it with that of the 1,320 nm Nd:YAG laser.
  
  
  METHODS
  Twelve patients with Fitzpatrick skin types I to III were randomly selected to have half of the face or back treated with the Lyra 1,064 nm Nd:YAG laser (Laserscope Corporation, San Jose, CA, USA) and the other half with the CoolTouch II 1,320 nm Nd:YAG laser (ICN Pharmaceuticals, Inc., Costa Mesa, CA, USA). Three treatments at 4-week intervals were performed. Patients were evaluated by photographic and profilometric methods before and 6 months after the last treatment.
  
  
  RESULTS
  Immediate changes included mild erythema with the 1,064 nm Nd:YAG laser and mild edema and erythema with the 1,320 nm Nd:YAG laser. No long-term adverse changes were seen with either laser system. Using the 1,320 nm system, 42% of the patients had 30 to 40% clinical improvement, 42% had 11 to 29%, and 16% had 10% or less. With the 1,064 nm system, 58% had 30 to 40% clinical improvement and 42% had 11 to 29%. Average improvement in acne scars evaluated by three independent observers was 22% with the 1,320 nm laser compared with 28% with the 1,064 nm laser. The subjects' own grading was 39% with the 1,320 nm laser compared with 37% for the 1,064 nm laser. Prolifometric studies demonstrated comparable improvement, with no statistical difference using either laser.
  
  
  CONCLUSIONS
  These data indicate that both the 1,064 nm laser and the 1,320 nm Nd:YAG laser are safe and effective systems for the nonablative treatment of acne scars, achieving similar improvement. There appears to be a greater response with the 1,064 nm laser system as assessed by the clinical investigators.
authors.affiliation: Department of Dermatology, Northwestern University, Chicago, IL 60611, USA. d-yaghmai@northwestern.edu
authors.forename: Dina
authors.initials: D
authors.lastname: Yaghmai
authors.forename: Jerome M
authors.initials: JM
authors.lastname: Garden
authors.forename: Abnoeal D
authors.initials: AD
authors.lastname: Bakus
authors.forename: Mary C
authors.initials: MC
authors.lastname: Massa
mesh_terms: D000152:Acne Vulgaris / Q000473:pathology / Q000532:radiotherapy*; D000328:Adult; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D016896:Treatment Outcome