Perpetuation of immunological memory: role of serum antibodies and accessory cells.
A self-sustaining mechanism for perpetuation of immunological memory is proposed which requires the involvement of idiotypic-anti-idiotypic antibody immune-complexes, antigen-presenting cells and follicular dendritic cells, but not long-lived memory cells or persisting antigens.
Nayak
Rabindranath
R
Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. nayak@mcbl.iisc.ernet.in
Lal
Girdhari
G
Shaila
M S
MS
D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology / Q000502:physiology*; D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology / Q000502:physiology*; D007156:Immunologic Memory / Q000276:immunology / Q000502:physiology*
D007136:Immunoglobulins