Novel Pd(II)-catalysed N,O-bicyclisation as an efficient route to the 6-oxa-2-azabicyclo[3.2.1]octane skeleton.
1-(Benzyloxycarbonylamino)-hex-5-en-3-ol undergoes a novel Pd(II)/CuCl2-catalysed bicyclisation to furnish the corresponding 6-oxa-2-azabicyclo[3.2.1]octane in good yield.
Szolcsányi
Peter
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Department of Organic Chemistry, Slovak University of Technology, Radlinského 9, 812 37, Bratislava, Slovakia. peter.szolcsanyi@stuba.sk
Gracza
Tibor
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D001643:Bridged Bicyclo Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D010165:Palladium / Q000737:chemistry*
D001643:Bridged Bicyclo Compounds; D010165:Palladium