title: CAR: three new models for a problem child.
abstract: By comparison with its older and better-behaved cousins in the nuclear receptor superfamily, CAR (NR1I3) has always been an oddball. Three new crystal structures recently described in Molecular Cell reveal the molecular basis for some of its bad habits (Xu et al., 2004; Suino et al., 2004; Shan et al., 2004).
authors.affiliation: Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: David D
authors.initials: DD
authors.lastname: Moore
mesh_terms: D020816:Amino Acid Motifs; D000818:Animals; D000090702:Constitutive Androstane Receptor; D006801:Humans; D008024:Ligands; D011485:Protein Binding; D011487:Protein Conformation; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry* / Q000502:physiology*; D014157:Transcription Factors / Q000737:chemistry* / Q000502:physiology*; D015533:Transcriptional Activation
chemical_list: D000090702:Constitutive Androstane Receptor; D008024:Ligands; C000716327:NR1I3 protein, human; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors