title: Nitrite mitigates lipid peroxidation in rat gastric mucosa.
abstract: Sodium nitrite, a nitric oxide (NO) donor in the acid pH, has been found to mitigate lipid peroxidation in rat gastric mucosa, and it elevated both Cu, Zn- and Mn-forms of the superoxide dismutase in this tissue. Putrescine, a simple polyamine of anti-oxidant properties has been shown to normalize lipid peroxidation levels in nitrite-treated animals.
authors.affiliation: Department of Applied Physiology, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.
authors.forename: Ireneusz P
authors.initials: IP
authors.lastname: Grudziński
authors.forename: Anna
authors.initials: A
authors.lastname: Frankiewicz-Jóźko
authors.forename: Ewa
authors.initials: E
authors.lastname: Szarska
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology; D005753:Gastric Mucosa / Q000187:drug effects / Q000201:enzymology*; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D011700:Putrescine / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012977:Sodium Nitrite / Q000633:toxicity*; D013482:Superoxide Dismutase / Q000187:drug effects / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D013482:Superoxide Dismutase; D012977:Sodium Nitrite; D011700:Putrescine