[Age features of haemostasis in human].
In article the items of information of the literature and own data of the authors on changes haemostasis in humans, since the moment of birth and finishing old age are resulted. It is shown, that platelet aggregation enhances, ability of lymphocytes to form the co-aggregates with platelets decreases, blood coagulation increases, fibrinolysis depresses in elderly and old people. The received data are explained by increase with age of the contents pro-inflammatory cytokines, resulting to the amplified synthesis of inductors of aggregation, tissue factor and inhibitors of fibrinolysis by monocytes, macrophages and endothelium of vessel wall.
Kuznik
B I
BI
Vitkovskiĭ
Iu A
IuA
Liul'kina
E V
EV
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000276:immunology*; D001792:Blood Platelets / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D016207:Cytokines / Q000378:metabolism*; D005260:Female; D005342:Fibrinolysis / Q000502:physiology; D006487:Hemostasis / Q000276:immunology*; D006801:Humans; D007223:Infant; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology; D012307:Risk Factors; D013927:Thrombosis / Q000503:physiopathology
D016207:Cytokines