title: Design, synthesis, and evaluation of novelly substituted benzimidazole compounds as angiotensin II receptor antagonists.
abstract: 5-Nitrobenzimidazole derivatives with varying substituents at 2-position have been designed, synthesized, and evaluated for angiotensin II antagonistic activity. A drug-receptor interaction model has been proposed.
authors.affiliation: University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh, India.
authors.forename: Alka
authors.initials: A
authors.lastname: Bali
authors.forename: Yogita
authors.initials: Y
authors.lastname: Bansal
authors.forename: M
authors.initials: M
authors.lastname: Sugumaran
authors.forename: Jatinder Singh
authors.initials: JS
authors.lastname: Saggu
authors.forename: P
authors.initials: P
authors.lastname: Balakumar
authors.forename: Gurpreet
authors.initials: G
authors.lastname: Kaur
authors.forename: Gulshan
authors.initials: G
authors.lastname: Bansal
authors.forename: Ajay
authors.initials: A
authors.lastname: Sharma
authors.forename: Manjeet
authors.initials: M
authors.lastname: Singh
mesh_terms: D057911:Angiotensin Receptor Antagonists; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D015195:Drug Design; D008958:Models, Molecular; D011485:Protein Binding; D013329:Structure-Activity Relationship
chemical_list: D057911:Angiotensin Receptor Antagonists; D001562:Benzimidazoles