Kinetic isotope effects on thio-substituted biological phosphoryl transfer reactions from density-functional theory.
Primary and secondary kinetic and equilibrium isotope effects are calculated with density-functional methods for the dianionic methanolysis of the native (unsubstituted) and thio-substituted ethylene phosphates.
Liu
Yun
Y
Department of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN 55455, USA.
Lopez
Xabier
X
York
Darrin M
DM
D007554:Isotopes / Q000737:chemistry*; D007700:Kinetics; D017553:Phosphorus Compounds / Q000737:chemistry*; D013816:Thermodynamics
D007554:Isotopes; D017553:Phosphorus Compounds