title: [Cytokine-producing activity of peripheral mononuclear leukocytes in patients with pulmonary tuberculosis before and during chemotherapy].
abstract: The paper presents the results of a study of spontaneous and stimulated production of TNF-alpha, INF-gamma, INF-alpha, IL-2 by peripheral mononuclear leukocytes in patients with disseminated destructive drug-resistant pulmonary tuberculosis. It also shows marked changes in the levels the studied cytokines in relation to the type of a stimulant (lipopolysaccharide, phytohemagglutinin, tuberculin) and during antituberculous chemotherapy.
authors.forename: V V
authors.initials: VV
authors.lastname: Novitskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Sinitsyna
authors.forename: O V
authors.initials: OV
authors.lastname: Voronkova
authors.forename: A K
authors.initials: AK
authors.lastname: Strelis
authors.forename: O I
authors.initials: OI
authors.lastname: Urazova
authors.forename: O V
authors.initials: OV
authors.lastname: Filiniuk
authors.forename: N A
authors.initials: NA
authors.lastname: Zemlianaia
authors.forename: T A
authors.initials: TA
authors.lastname: Luk'ianova
authors.forename: I E
authors.initials: IE
authors.lastname: Esimova
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D016207:Cytokines / Q000187:drug effects* / Q000378:metabolism*; D005260:Female; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000187:drug effects* / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents; D016207:Cytokines