Diastereoselective Ni(0)-catalyzed carbocyclization to chiral vinylic sulfoxide.
Diastereoselective Ni(0)-catalyzed carbocyclization of enone to chiral vinylic sulfoxide has been accomplished, wherein two stereogenic centers were constructed simultaneously to give cis- and trans-disubstituted cyclopentanes from (E)- and (Z)-vinylic sulfoxides, respectively.
Maezaki
Naoyoshi
N
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
Sawamoto
Hiroaki
H
Ishihara
Hiroyuki
H
Tanaka
Tetsuaki
T
D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D009532:Nickel / Q000737:chemistry*; D013237:Stereoisomerism; D013454:Sulfoxides / Q000737:chemistry*
C519113:8-phenyl-1,6-octadienyl tolyl sulfide S-oxide; D013454:Sulfoxides; D009532:Nickel