title: [Influence of melatonin, serotonin and gastrin on streaming of chronic gastritis at elderly patients].
abstract: In development of chronic gastritis of elderly persons there has been increased the functional activity of diffuse neuroendocrine systems, especially EC-cells. It results in decreasing of the indexes of proliferationand increasing of apoptosis index. At patients with chronic gastritis in elderly, we found diffuse lesion of gastric mucous, combination with intestinal methaplasy and atrophy of stomach mucous more often. The further studying of processes of cellular updating and mechanisms of regulation of apoptosis and proliferation will allow stopping the development of chronic gastritis and occurrence of its irreversible complications at early stage.
mesh_terms: D000368:Aged; D017209:Apoptosis; D002908:Chronic Disease; D018450:Disease Progression; D004759:Enterochromaffin Cells / Q000276:immunology / Q000378:metabolism*; D005753:Gastric Mucosa / Q000473:pathology; D005755:Gastrins / Q000032:analysis / Q000378:metabolism*; D005756:Gastritis / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008550:Melatonin / Q000032:analysis / Q000378:metabolism*; D012701:Serotonin / Q000032:analysis / Q000378:metabolism*
chemical_list: D005755:Gastrins; D012701:Serotonin; D008550:Melatonin