title: Techniques of SNP genotyping and remote sensing applied for elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype.
abstract: We present a conceptual framework for applying techniques of SNP genotyping as a molecular biological approach and remote sensing as an ecological approach to elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype. Additionally, we discuss the obstacles that frustrate our efforts to identify how the human genome encodes the complex phenotype and suggest the use of computational methods designed for knowledge discovery within hereditary database.
authors.affiliation: Department of Engineering, Shibaura Institute of Technology, Tokyo, Japan. annou@sic.shibaura-it.ac.jp
authors.forename: Sumiko
authors.initials: S
authors.lastname: Anno
authors.forename: Susumu
authors.initials: S
authors.lastname: Kudo
authors.forename: Keita
authors.initials: K
authors.lastname: Hamasaki
authors.forename: Kazunari
authors.initials: K
authors.lastname: Matsumura
authors.forename: Takushi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Koretsugu
authors.initials: K
authors.lastname: Ogata
mesh_terms: D001272:Atmosphere / Q000032:analysis; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D004777:Environment; D014644:Genetic Variation; D015894:Genome, Human; D005838:Genotype; D006801:Humans; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012880:Skin Pigmentation / Q000235:genetics*; D013053:Spectrophotometry / Q000379:methods; D013686:Telemetry / Q000379:methods