title: The effect of esophageal myotomy and myectomy on the lower esophageal sphincter pressure profile: intraoperative computerized manometry study.
abstract: The surgical treatment of achalasia, based on Heller's myotomy is the procedure of choice to reduce the sphincterial high pressure zone, either by laparotomy or, most recently, by laparoscopy. What is the right length of the myotomy? Many authors have reported 10-15% postoperative residual dysphagia, due to the incomplete gastric myotomy and not to esophageal pouring. The aim of this study is to experimentally determine the modifications induced by Heller's myotomy and myectomy of the esophago-gastric junction on lower esophageal sphincter (LES) pressure profile, using a computerized manometric system. Myotomy of the esophageal portion of the LES (i.e. without dissection of the gastric fibers) has not modified the parameters considered, while the dissection of gastric fibers for at least 2-3 cm on the anterior gastric wall has created a significant modification of the LES pressure profile. Our observations seem to confirm and more clearly demonstrate the important role played by gastric fibers in sustaining the sphincteric HPZ. Moreover, analysis of our data, showed the need to always perform a complete myotomy. This was objectively shown during the intervention by means of intraoperative manometry, in order to significantly reduce the possibility of a dysphagic relapse, caused by inadequate treatment.
authors.affiliation: Second University of Naples, School of Medicine, Naples, Italy. natale.dimartino@unina2.it
authors.forename: N
authors.initials: N
authors.lastname: Di Martino
authors.forename: L
authors.initials: L
authors.lastname: Monaco
authors.forename: G
authors.initials: G
authors.lastname: Izzo
authors.forename: A
authors.initials: A
authors.lastname: Cosenza
authors.forename: F
authors.initials: F
authors.lastname: Torelli
authors.forename: A
authors.initials: A
authors.lastname: Basciotti
authors.forename: A
authors.initials: A
authors.lastname: Brillantino
mesh_terms: D000818:Animals; D013505:Digestive System Surgical Procedures; D049630:Esophageal Sphincter, Lower / Q000502:physiology* / Q000601:surgery*; D004947:Esophagus / Q000502:physiology* / Q000601:surgery*; D008365:Manometry; D023421:Models, Animal; D011312:Pressure; D013552:Swine