title: Contrast-enhanced power Doppler sonography of malignant ovarian tumors using harmonic flash-echo imaging: preliminary experience.
abstract: To investigate the potential usefulness of contrast-enhanced intermittent harmonic sonography in the diagnosis of ovarian cancer, we evaluated 4 patients with complex adnexal masses suspected of malignancy using intermittent harmonic sonography after injection of a contrast agent. Tumor and/or mural nodule tissue enhancement was detected in all cases of ovarian malignancy. Contrast-enhanced, intermittent harmonic sonography provides a satisfactory visualization of blood flow in the solid portion of the tumor tissue and may support a diagnosis of ovarian malignancy. Depiction of blood vessels using low MI techniques may be possible with other vascular ultrasonographic contrast agents.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Osaka University, 2-2, Yamadaoka, Suita, Osaka 5650871, Japan.
authors.forename: Masatomo
authors.initials: M
authors.lastname: Kohzuki
authors.forename: Toru
authors.initials: T
authors.lastname: Kanzaki
authors.forename: Yuji
authors.initials: Y
authors.lastname: Murata
mesh_terms: D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011134:Polysaccharides; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler; D018615:Ultrasonography, Doppler, Color
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508