title: Lack of response to systemic corticosteroids in patients with lymphangioma.
abstract: Lymphangioma is a benign nonencapsulated orbital tumor that is difficult to treat. Recently, systemic corticosteroids were advocated as a safe and effective alternative to surgical drainage of the cysts. We describe our experience with 3 cases in which proptosis progressed or did not improve despite the exclusive use of systemic steroids for 1 week, necessitating urgent surgical intervention. These three cases demonstrate that at least in some cases, steroids alone may be ineffective, and alternative interventions must be undertaken.
authors.affiliation: Department of Ophthalmology, Ain-Shams University, Cairo, Egypt. hatem35@yahoo.com
authors.forename: Hatem A
authors.initials: HA
authors.lastname: Tawfik
authors.forename: Hamida
authors.initials: H
authors.lastname: Budin
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Dutton
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008202:Lymphangioma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone