title: [Accumulation of genetic and epigenetic alterations: a key causal process between the environment and diseases of complex etiology].
authors.forename: Miquel
authors.initials: M
authors.lastname: Porta
authors.forename: Marta
authors.initials: M
authors.lastname: Crous
mesh_terms: D000483:Alleles; D000818:Animals; D030801:Animals, Genetically Modified; D004260:DNA Repair; D004777:Environment; D044127:Epigenesis, Genetic; D005260:Female; D015870:Gene Expression; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005826:Genetics, Medical; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D017720:Molecular Epidemiology; D009154:Mutation; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D012307:Risk Factors