title: [The efficiency of the use of cerebrolysin in optic nerve diseases in children of different age].
abstract: The purpose of the study was to evaluate the efficiency of cerebrolysin used in partial atrophies of the optic nerve in relation to the method of drug injection and to whether treatment was used in combination with percutaneous electrostimulation of the optic nerve. The study was based on the results of clinical and electrophysiological studies of 646 children (810 eyes) aged 8 weeks to 18 years. All the examinees were divided into 4 groups: 1) patients in whom cerebrolysin was administered as retrobulbar injections made once daily; 2) those in whom cerebrolysion was injected in combination with microcirculation-improving agents through the irrigation system into the retrobulbar and Tenon space; 3) patients who received cerebrolysin only through the irrigation system; 4) those in whom the agents affecting the microcirculatory bed in the optic nerve system were administered through the irrigation system. Cerobrolysin has turned out to be highly effective as a drug that improved the outcomes of percutaneous stimulation of the optic nerve due to the use of two-stage treatment of children with partial atrophy of the optic nerve of various genesis, involving irrigation therapy supplemented by cerebrolysin and vascular agents at the first stage and percutaneous stimulation of the optic nerve at the second one.
authors.forename: M R
authors.initials: MR
authors.lastname: Guseva
authors.forename: L A
authors.initials: LA
authors.lastname: Dubovsakia
mesh_terms: D000293:Adolescent; D000596:Amino Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004333:Drug Administration Routes; D004569:Electroencephalography; D004596:Electroretinography; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D009900:Optic Nerve / Q000187:drug effects / Q000503:physiopathology; D009901:Optic Nerve Diseases / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000596:Amino Acids; D018696:Neuroprotective Agents; C006952:cerebrolysin