Performance of community-based glaucoma screening using Frequency Doubling Technology and Heidelberg Retinal Tomography.
OBJECTIVE
To assess the performance of a community-based glaucoma screening algorithm in the general population.


METHODS
A total of 659 individuals aged 50-90 years were screened for glaucoma. Presenting visual acuity, family history of glaucoma, FDT perimetry, and HRT tests were assessed. Additional samples of participants served as control groups. Participants identified as glaucoma positive received a full ophthalmic examination. Based on this exam a consensus diagnosis was made which served as the gold standard.


RESULTS
The optimal screening strategy combining visual acuity and family history with FDT and HRT had sensitivities, specificities, positive predictive values and negative predictive values of 96.8%, 89.7%, 31.9%, and 99.8% respectively for detecting glaucoma.


CONCLUSIONS
By combining assessments of presenting visual acuity and family history of glaucoma with Frequency Doubling Technology perimetry and Heidelberg Retina Tomography, we devised a community glaucoma-screening algorithm that showed a high sensitivity and specificity for detecting glaucoma in the general population.
Robin
Todd A
TA
Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, East Melbourne, Victoria 3002, Australia.
Müller
Andreas
A
Rait
Julian
J
Keeffe
Jill E
JE
Taylor
Hugh R
HR
Mukesh
Bickol N
BN
D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D002908:Chronic Disease; D003941:Diagnostic Techniques, Ophthalmological; D016021:Epidemiologic Studies; D005189:False Positive Reactions; D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D018511:Systems Integration; D014054:Tomography; D014786:Vision Disorders / Q000175:diagnosis*; D014792:Visual Acuity; D014794:Visual Fields