title: Temporomandibular joint destruction in mucolipidosis type III necessitating gastrostomy insertion.
abstract: Mucolipidosis III is a genetically heterogeneous lysosomal disorder characterised by progressive symptoms and signs, the commonest being skeletal pain due to bony destruction. We describe a patient who developed severe destruction of the temporomandibular joints leading to difficulties with speech and feeding, necessitating gastrostomy insertion.
  
  
  CONCLUSIONS
  Temporomandibular joint involvement has not been previously reported in mucolipidosis III.
authors.affiliation: Metabolic Unit, Great Ormond Street Hospital, London, UK.
authors.forename: Zarzuela
authors.initials: Z
authors.lastname: Zolkipli
authors.forename: Lee
authors.initials: L
authors.lastname: Noimark
authors.forename: Maureen A
authors.initials: MA
authors.lastname: Cleary
authors.forename: Cathy
authors.initials: C
authors.lastname: Owens
authors.forename: Ashok
authors.initials: A
authors.lastname: Vellodi
mesh_terms: D000293:Adolescent; D005260:Female; D005774:Gastrostomy; D006801:Humans; D009081:Mucolipidoses / Q000150:complications*; D013705:Temporomandibular Joint Disorders / Q000209:etiology* / Q000503:physiopathology