title: Clinical application of 11-deoxycortisol in visualizing prolapsed vitreous body after posterior capsule rupture in cataract surgery.
abstract: OBJECTIVE
  To evaluate the clinical usefulness of 11-deoxycortisol, a precursor of cortisol in steroid metabolism, in visualizing the vitreous body in the anterior chamber after posterior capsule rupture during cataract surgery.
  
  
  METHODS
  Department of Ophthalmology, Tsukuba University Hospital, Ibaraki, Japan.
  
  
  METHODS
  Eight eyes had anterior vitrectomy during cataract surgery using this new technique. A suspension of 11-deoxycortisol was prepared by dilution in balanced salt solution without preservatives or emulsifying agents. After a posterior capsule rupture, the suspension was injected into the anterior chamber. The visual and anatomical outcomes of surgery were evaluated during a follow-up of 7 to 9 months.
  
  
  RESULTS
  After the 11-deoxycortisol injection, the vitreous body that had prolapsed through the torn posterior capsule, with white particles entrapped on its surface, became clearly visible. Complete removal of the prolapsed vitreous body was achieved easily and safely using an anterior vitrectomy system. No postoperative complications related to the use of 11-deoxycortisol were observed.
  
  
  CONCLUSIONS
  Injection of 11-deoxycortisol helped visualize the vitreous body in the anterior chamber after posterior capsule rupture. The technique minimized intraoperative and postoperative complications related to posterior capsule rupture and vitreous loss during cataract surgery [corrected]
authors.affiliation: Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Tennoudai, Tsukuba 305-8575, Ibaraki, Japan. sanken-tky@umin.ac.jp
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kaji
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hiraoka
authors.forename: Fumiki
authors.initials: F
authors.lastname: Okamoto
authors.forename: Masaki
authors.initials: M
authors.lastname: Sato
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Oshika
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D003350:Cortodoxone; D005128:Eye Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D018918:Phacoemulsification / Q000009:adverse effects* / Q000295:instrumentation; D057851:Posterior Capsular Rupture, Ocular / Q000175:diagnosis* / Q000209:etiology; D011391:Prolapse; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology*
chemical_list: D003350:Cortodoxone