[Effect of oxytocin on the activity of neurons in posterior hypothalamic regions of stressed rats].
The dynamics of pulse activity in the cells of posterior hypothalamic regions was studied in acute experiments on white rats treated with oxytocin. Intravenous injections of the drug induced dose-dependent reorganization of the neuron discharge both in intact rats and in animals with obvious emotional sexual stress. The dose-dependent effect was observed in various latent periods of the neuron response and was manifested by changes in the character of pulsation. The higher the background frequency of cell pulses, the less pronounced was the neuron response to the drug. In some cases, the drug intensified the burst activity and produced regulation of the discharge rhythm.
Mukhitdinova
Kh N
KhN
Stamova
L G
LG
Rasulov
M M
MM
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D007034:Hypothalamus, Posterior / Q000166:cytology*; D008297:Male; D009474:Neurons / Q000187:drug effects*; D010121:Oxytocin / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000503:physiopathology*
D014151:Anti-Anxiety Agents; D010121:Oxytocin