title: [Cardiac amyloidosis revealing multiple myeloma].
abstract: BACKGROUND
  Amyloidosis is a rare disease characterized by an extracellular accumulation of a protein polysaccharid complex (Amyloid). Cardiac involvement is considered as a major prognostic factor.
  
  
  METHODS
  We report the case of two women, hospitalized for heart failure. The diagnosis of cardiac amyloidosis was suggested by echocardiography: Left ventricular concentric hypertrophy and typical amyeloid infiltration with hyperechoic, shiny and granite-like aspect of the interventricular septum. The histological confirmation was obtained by gastric biopsy in the first case and biopsy of the salivary glands in the second revealing an amyloidosis AL. This cardiac amyloidosis was secondary to multiple myeloma: monoclonal Gammopathy with immunoglobulin Lambda in the first and Kappa in the second, and the presence of a plasmocyte infiltration in the sternal puncture.
  
  
  CONCLUSIONS
  Amyloidosis is a rare pathology, the cardiac involvement is frequent in the type AL and can occur with or without clinical manifestations. Echocardiography should be systematic in patients with confirmed amyloidosis.
authors.affiliation: Service de cardiologie du CHU de Monastir.
authors.forename: Hichem
authors.initials: H
authors.lastname: Denguir
authors.forename: Khaldoun
authors.initials: K
authors.lastname: Ben-Hamda
authors.forename: Mostari
authors.initials: M
authors.lastname: Gharbi
authors.forename: Faouzi
authors.initials: F
authors.lastname: Addad
authors.forename: Sonia
authors.initials: S
authors.lastname: Hammami
authors.forename: Azmi
authors.initials: A
authors.lastname: Mlika
authors.forename: Fehmi
authors.initials: F
authors.lastname: Abbes
authors.forename: Adnene
authors.initials: A
authors.lastname: Moussa
authors.forename: Fethi
authors.initials: F
authors.lastname: Betbout
authors.forename: Habib
authors.initials: H
authors.lastname: Gamra
authors.forename: Faouzi
authors.initials: F
authors.lastname: Maatouk
authors.forename: Zohra
authors.initials: Z
authors.lastname: Dridi
authors.forename: Abdelfettah
authors.initials: A
authors.lastname: Zakhama
authors.forename: Sylvia
authors.initials: S
authors.lastname: Mahjoub
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ben-Farhat
mesh_terms: D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000209:etiology*; D001706:Biopsy; D004452:Echocardiography; D005260:Female; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis*; D011379:Prognosis