[Expression of galectin-3 in invasive prolactinomas].
OBJECTIVE
To investigate the expression of galectin-3 (Gal-3) in prolactinomas.


METHODS
Expressions of Gal-3 were evaluated by immunohistochemistry using polyclonal antibody in 16 invasive prolactinomas and 16 prolactinomas.


RESULTS
Gal-3 was expressed both in invasive prolactinomas and noninvasive prolactinomas while significantly higher expression seen in the invasive prolactinomas (P < 0.05).


CONCLUSIONS
Gal-3 expression may be used as a useful indicator to determine the invasiveness and prognosis of prolactinomas.
Wang
Hong
H
Department of Neurosurgery, Affiliated Hospital of Hebei Medical College for Continuous Education, Baoding 071000, China.
Wang
Ming-dong
MD
Ma
Wen-bin
WB
Yang
Di
D
Shi
Yan-Fang
YF
Kong
Yan-guo
YG
Li
Shi-fang
SF
Li
Zhi-hong
ZH
Wang
Ren-zhi
RZ
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D037502:Galectin 3 / Q000096:biosynthesis* / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000473:pathology; D011379:Prognosis; D015175:Prolactinoma / Q000378:metabolism* / Q000473:pathology
D037502:Galectin 3