[Hepatosplenic and kidneys candidasis complicating an acute myeloblastic leukemia. A case treated with voriconazole and caspofungin].
We report the observation of hepato-splenic and kidneys candidiasis complicating the chemotherapy of a myeloblastic leukemia (LAM5b). Following the lack of effectiveness of a first line treatement, using amphotericine B liposomale and 5-fluorocytosine, implementation of an association of new molecules, a triazole of second generation (voriconazole) and an echinocandine (caspofungine) has allowed a successful result.
Elouennass
M
M
Service de biologie médicale, hôpital d'instruction des armées Percy, Clamart. elouennassm@yahoo.fr
Doghmi
K
K
Fagot
T
T
Soler
C
C
Mac Nab
C
C
Foissaud
V
V
De Revel
T
T
Hervé
V
V
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000077336:Caspofungin; D054714:Echinocandins; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000382:microbiology*; D015470:Leukemia, Myeloid, Acute / Q000382:microbiology*; D055666:Lipopeptides; D008107:Liver Diseases / Q000382:microbiology*; D010456:Peptides, Cyclic / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D013158:Splenic Diseases / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D011743:Pyrimidines; D014230:Triazoles; D000077336:Caspofungin; D065819:Voriconazole