[Effects of UV-radiation on metabolism and structural-functional status of the rat's erythrocyte membranes].
In-vitro analysis of venous blood taken from rats irradiated by 300 and 5,000 J/m2 of UV showed no effect on metabolism and, therefore, energy and recovery systems of erythrocytes. Concentrations of 2,3-diphosphoglycerate and reduced glutathione were increased after irradiation by 5,000 J/m2. UV-irradiation at 10,000 J/m2 decreased adenosine triphosphate and phospholipids in blood and impaired the functional stability of erythrocyte membranes. Recovery of the membrane structure in 24 hrs. after irradiation suggests extended photochemical processes in cells and is consistent with the literary data about indirect effects of plasma proteins on the red cell function.
Iarlykova
Iu V
IuV
Ivanova
S M
SM
Labetskaia
O I
OI
D000222:Adaptation, Physiological / Q000502:physiology; D000251:Adenosine Triphosphatases / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D004163:Diphosphoglyceric Acids / Q000378:metabolism / Q000528:radiation effects; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000528:radiation effects*; D005978:Glutathione / Q000378:metabolism / Q000528:radiation effects; D066298:In Vitro Techniques; D010743:Phospholipids / Q000378:metabolism / Q000528:radiation effects; D011829:Radiation Dosage; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014466:Ultraviolet Rays
D004163:Diphosphoglyceric Acids; D010743:Phospholipids; D000251:Adenosine Triphosphatases; D005978:Glutathione