Regulatory functions of the lambda repressor reside in the amino-terminal domain.
The repressor of bacteriophage lambda is a protein containing two domains of approximately equal size. Fragments containing the amino-terminal domain of repressor bind specifically to lambda operator DNA and mediate positive and negative control of lambda transcription both in vitro and in vivo.
Sauer
R T
RT
Pabo
C O
CO
Meyer
B J
BJ
Ptashne
M
M
Backman
K C
KC