Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form.
OBJECTIVE
Compliance with our local hospital policy for gentamicin administration and monitoring was found to be inadequate on audit. A gentamicin monitoring form was introduced with the aim of improving staff compliance with the policy thus minimizing the risks of toxicity while ensuring adequate dosing.


METHODS
The initial audit examined the prescribing, administration and monitoring of intravenous gentamicin given to 20 patients. The introduction of a gentamicin monitoring form was prompted by unsatisfactory initial dosing and subsequent monitoring and adjustment of gentamicin doses.


RESULTS
Following introduction of the monitoring form, the proportion of appropriate starting doses had increased from 13 out of 20 to 18 out of 20 prescriptions. The timing of initial serum levels was significantly better: 18 timed correctly, compared with 12 in initial audit. Subsequent administration and monitoring appeared more compliant with fewer doses inappropriately omitted and more levels checked appropriately. No improvement was seen in the quality of dose adjustment.


CONCLUSIONS
In conjunction with the support and advice of the pharmacy and microbiology departments, the use of a gentamicin monitoring form can improve the quality of intravenous gentamicin use in the hospital setting.
Rogers
Matthew S
MS
Department of Microbiology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry & Warwickshire Hospital, Stoney Stanton Road, Coventry CV1 4FH, UK.
Cullen
Mairi M
MM
Boxall
Emma M
EM
Chadwick
Paul R
PR
D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016903:Drug Monitoring / Q000379:methods*; D011307:Drug Prescriptions; D004363:Drug Utilization; D017723:Drug Utilization Review; D005839:Gentamicins / Q000009:adverse effects / Q000627:therapeutic use*; D019983:Guideline Adherence / Q000458:organization & administration; D006761:Hospitals; D006801:Humans; D007239:Infections / Q000188:drug therapy; D007668:Kidney / Q000187:drug effects; D007674:Kidney Diseases / Q000139:chemically induced / Q000503:physiopathology
D000900:Anti-Bacterial Agents; D005839:Gentamicins