Systems biology in malaria research.
A recent publication of genome and expression analyses of the murine parasites Plasmodium chabaudi chabaudi and Plasmodium berghei presents the state of the art in Plasmodium systems biology. By integrating genomics, transcriptomics and proteomics, the authors can classify and annotate genes by their expression profiles and can even detect evidence of posttranscriptional gene silencing in the murine malaria species.
Fraunholz
Martin J
MJ
Junior Group Applied Bioinformatics and Cell Biology, Institute of Microbiology, Ernst Moritz Arndt University, Friedrich-Ludwig-Jahn Strasse 15, D-17487 Greifswald, Germany. martin.fraunholz@uni-greifswald.de
D000818:Animals; D020869:Gene Expression Profiling; D017125:Genes, Protozoan; D018503:Genome, Protozoan; D006801:Humans; D008288:Malaria / Q000469:parasitology*; D010962:Plasmodium berghei / Q000235:genetics*; D016788:Plasmodium chabaudi / Q000235:genetics*; D034622:RNA Interference; D012106:Research