Effect of a low protein diet on the resistance of Churra sheep to Teladorsagia circumcincta.
SUMMARY The aim of this study was to understand the influence of a low protein diet on the resistance of the Churra breed sheep to infection with Teladorsagia circumcincta. A previous experiment in our department demonstrated significant differences between resistant and susceptible sheep infected with T. circumcincta, in eggs per gram of faeces, serum pepsinogen, serum IgA and peripheral eosinophilia (unpublished). The sheep were fed with a balanced protein diet. In the current assay there were significant differences between the resistant and susceptible groups in egg output, serum pepsinogen and worm burden. The optical densities (OD) of the IgA in blood samples, nasal secretions and saliva were tested throughout the study and the differences between groups were not significant. At necropsy adult worm length, the number of eggs in utero in adult females, the number of fourth stage larvae and the OD of gastric mucus IgA did not differ between groups either. Moreover, due to diet there was a loss of weight in both groups but this was not significant. Our results support the view that low protein diets could influence immune function and as a result resistant genotypes do not show any superiority in comparison with susceptible ones.
Martínez-Valladares
M
M
Departamento Sanidad Animal, Parasitología, Facultad de Veterinaria, Universidad de León, León, Spain.
Vara-Del Río
M P
MP
Cruz-Rojo
M A
MA
Rojo-Vázquez
F A
FA
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D004044:Dietary Proteins / Q000276:immunology / Q000494:pharmacology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D004802:Eosinophilia / Q000469:parasitology / Q000662:veterinary; D005243:Feces / Q000469:parasitology; D005260:Female; D005767:Gastrointestinal Diseases / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D007113:Immunity, Innate / Q000502:physiology; D007070:Immunoglobulin A / Q000097:blood; D009297:Nasal Mucosa / Q000469:parasitology; D009752:Nutritional Status / Q000502:physiology; D010270:Parasite Egg Count / Q000662:veterinary; D020116:Pepsinogen A / Q000097:blood; D012463:Saliva / Q000469:parasitology; D012756:Sheep / Q000276:immunology*; D012757:Sheep Diseases / Q000276:immunology* / Q000469:parasitology*; D014251:Trichostrongyloidea / Q000276:immunology*; D014252:Trichostrongyloidiasis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*
D000909:Antibodies, Helminth; D004044:Dietary Proteins; D007070:Immunoglobulin A; D020116:Pepsinogen A