The prepared mind of the worm.
In C. elegans, dauer pheromone is an indicator of population density and influences pathways that regulate metabolism, development, and aging. In a recent publication in Nature, Paik and coworkers (Jeong at al., 2005) show the purified substance to be a pyran ring conjugated to heptanoic acid, setting the stage for dissecting downstream signaling pathways.
Antebi
Adam
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Huffinton Center an Aging and Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Room M-320, Houston, Texas 77030, USA.
D000222:Adaptation, Physiological; D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry* / Q000502:physiology*; D010675:Pheromones / Q000737:chemistry / Q000502:physiology; D015398:Signal Transduction
D010675:Pheromones