Capillary electrophoresis of the electrochemical oxidation products of Ng-hydroxy-l-arginine at physiological pH.
Ng-hydroxy-l-arginine has been described as an intermediate in the nitric oxide pathway. Its electrochemical oxidation was studied by capillary electrophoresis using either electrospray ionisation mass spectrometry or diode array detection. Three stable end products and unstable intermediates were found using these techniques. These results permitted to propose an electrochemical oxidation scheme of this molecule.
Meulemans
Alain
A
Faculté de Médecine Xavier Bichat, Laboratoire de Biophysique, 46 rue Henri Huchard, Paris 75018, France. alain.meulemans@voila.fr
D001120:Arginine / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D015538:Nitrosation; D010084:Oxidation-Reduction; D015203:Reproducibility of Results
C068309:N(omega)-hydroxyarginine; D001120:Arginine