Pratical aspects of testosterone substitution.
Until more data on the efficacy and risks of testosterone (T) treatment of hypogonadal older men become available, the use of T substitution in men in this age group should be carefully considered and benefits vs risks should be discussed with the patient. Generally symptoms of hypogonadism together with low serum T levels are considered indications for treatment. For aging men, short acting preparations may be preferred and levels of serum T are maintained with in the mid adult range. Careful assessment for improvement of symptoms is the essential goal of treatment. Monitoring for manifestations of prostate disease, erythrocytosis and other adverse events of androgen treatment is critical in the management of older men with androgen replacement therapy.
Wang
C
C
Division of Endocrinology, Department of Medicine Harbor-UCLA Medical Center and Los Angeles Biomedical Research Center, Torrance, USA. wang@labiomed.org
Swerdloff
R S
RS
D000368:Aged; D000375:Aging; D000075202:Contraindications; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy; D008297:Male; D013739:Testosterone / Q000008:administration & dosage* / Q000009:adverse effects / Q000172:deficiency; D016896:Treatment Outcome
D013739:Testosterone