title: Influence of a fat layer on the near infrared spectra of human muscle: quantitative analysis based on two-layered Monte Carlo simulations and phantom experiments.
abstract: The influence of fat thickness on the diffuse reflectance spectra of muscle in the near infrared (NIR) region is studied by Monte Carlo simulations of a two-layer structure and with phantom experiments. A polynomial relationship was established between the fat thickness and the detected diffuse reflectance. The influence of a range of optical coefficients (absorption and reduced scattering) for fat and muscle over the known range of human physiological values was also investigated. Subject-to-subject variation in the fat optical coefficients and thickness can be ignored if the fat thickness is less than 5 mm. A method was proposed to correct the fat thickness influence.
authors.affiliation: Department of Anesthesiology, University of Massachusetts Medical School, Worcester, MA 01655, USA. ye.yang@umassmed.edu
authors.forename: Ye
authors.initials: Y
authors.lastname: Yang
authors.forename: Olusola O
authors.initials: OO
authors.lastname: Soyemi
authors.forename: Michelle R
authors.initials: MR
authors.lastname: Landry
authors.forename: Babs R
authors.initials: BR
authors.lastname: Soller
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D007259:Infrared Rays; D008954:Models, Biological; D009010:Monte Carlo Method; D009132:Muscles / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D011859:Radiography; D013055:Spectrophotometry, Infrared; D041622:Tomography, Optical / Q000379:methods