title: Cemented cup stability during lever-out testing after acetabular bone impaction grafting with bone graft substitutes mixes containing morselized cancellous bone and tricalcium phosphate--hydroxyapatite granules.
abstract: Bone defects after failed total hip arthroplasty can be reconstructed with impacted morselized bone grafts and a cemented cup. In the near future the amount of bone grafts available for surgical purposes will be insufficient. Ceramic calcium phosphates [tricalcium phosphate (TCP) and hydroxyapatite (HA)] have been widely considered as potential bone graft substitutes or bone graft extenders. In the past, mechanical experiments have been performed to determine implant stability of bone grafts and ceramic TCP-HA granules mixes under a compressive load. However, in-vivo migration studies suggest that shear loading may be equally important. This in-vitro study investigated the initial stability of cups reconstructed with various mixes of bone grafts and ceramic TCP-HA granules in a lever-out situation, where shearing is the predominant loading mode. It was found that the cups reconstructed with mixes of bone graft and TCP-HA granules exhibited greater mechanical stability than the cups reconstructed with bone grafts only. It is concluded that from a mechanical standpoint, when considering shear force resistance, 50-50 per cent volume mix and 25-75 per cent volume mix of morselized cancellous bone graft and TCP-HA granules both provide adequate initial cup stability and can be used for acetabular reconstructions with the bone impaction grafting technique.
authors.affiliation: Radboud University Nijmegen Medical Centre, Orthopaedic Research Laboratory, Nijmegen, The Netherlands.
authors.forename: J J C
authors.initials: JJ
authors.lastname: Arts
authors.forename: B W
authors.initials: BW
authors.lastname: Schreurs
authors.forename: P
authors.initials: P
authors.lastname: Buma
authors.forename: N
authors.initials: N
authors.lastname: Verdonschot
mesh_terms: D000077:Acetabulum / Q000737:chemistry* / Q000503:physiopathology*; D000268:Adhesiveness; D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry; D001843:Bone Cements / Q000032:analysis / Q000737:chemistry*; D018786:Bone Substitutes / Q000032:analysis / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D010316:Particle Size
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; D017886:Durapatite; C018392:tricalcium phosphate