Vertebral osteomyelitis due to Fusobacterium species: report of three cases and review of the literature.
We describe three cases of Fusobacterium spp. diskitis and review with attention to risk factors, clinical features, diagnosis, treatment and outcome. In most of the reported cases, a ear-nose-throat infection was found. Clinical manifestations were similar to those of classic bacterial vertebral osteomyelitis. Clindamycin is the most appropriate antibiotic. The outcome seems to be very good without relapse with appropriate treatment compared to pyogenic vertebral osteomyelitis.
Le Moal
G
G
Service de Maladies Infectieuses, CHU La Milétrie, rue la milétrie, 86021 Poitiers, France. g.lemoal@chu-poitiers.fr
Juhel
L
L
Grollier
G
G
Godet
C
C
Azais
I
I
Roblot
F
F
D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D015299:Discitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D004359:Drug Therapy, Combination; D005260:Female; D005674:Fusobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005675:Fusobacterium necrophorum / Q000302:isolation & purification; D016967:Fusobacterium nucleatum / Q000302:isolation & purification; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D010406:Penicillins / Q000008:administration & dosage; D013122:Spinal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D013904:Thoracic Vertebrae; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D010406:Penicillins; D002981:Clindamycin