The significance of folic acid for epilepsy patients.
The following is a comprehensive review of the current understanding of the many important roles of folic acid in the health of patients with epilepsy. A review of past and current literature reveals that folic acid plays important roles in the areas of hematology, neurology, development, and reproduction. Also highlighted are new areas for exploration.
Moore
James Layne
JL
Department of Neurology, Ohio State University College of Medicine, 1654 Upham Drive, 4th Floor, Columbus, OH 43210, USA. moore.537@osu.edu
D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D005492:Folic Acid / Q000737:chemistry / Q000266:history / Q000378:metabolism* / Q000627:therapeutic use*; D049673:History, 20th Century; D006710:Homocysteine / Q000378:metabolism; D006801:Humans; D008297:Male; D008715:Methionine / Q000378:metabolism; D008954:Models, Biological; D009436:Neural Tube Defects / Q000188:drug therapy / Q000503:physiopathology; D011247:Pregnancy; D014652:Vascular Diseases / Q000188:drug therapy
D000927:Anticonvulsants; D006710:Homocysteine; D005492:Folic Acid; D008715:Methionine