Focal nodular hyperplasia of the liver: a sequela of tumor therapy.
Focal nodular hyperplasia (FNH) of the liver occurs with increased frequency in oncology patients after completion of tumor therapy. Its development may be related to the vascular damage induced by such therapy. We present three children who developed FNH after undergoing antineoplastic therapy for non-hepatic primary tumors. Recognition of this association in the appropriate patient population might obviate the need for biopsy.
Joyner
Benny L
BL
Department of Pediatrics, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
Levin
Terry L
TL
Goyal
Rakesh K
RK
Newman
Beverley
B
D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000209:etiology / Q000473:pathology; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008099:Liver / Q000000981:diagnostic imaging / Q000187:drug effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional
D000970:Antineoplastic Agents