title: Neural modeling and imaging of the cortical interactions underlying syllable production.
abstract: This paper describes a neural model of speech acquisition and production that accounts for a wide range of acoustic, kinematic, and neuroimaging data concerning the control of speech movements. The model is a neural network whose components correspond to regions of the cerebral cortex and cerebellum, including premotor, motor, auditory, and somatosensory cortical areas. Computer simulations of the model verify its ability to account for compensation to lip and jaw perturbations during speech. Specific anatomical locations of the model's components are estimated, and these estimates are used to simulate fMRI experiments of simple syllable production.
authors.affiliation: Department of Cognitive and Neural Systems, Boston University, 677 Beacon Street Boston, MA 02215, USA. guenther@cns.bu.edu
authors.forename: Frank H
authors.initials: FH
authors.lastname: Guenther
authors.forename: Satrajit S
authors.initials: SS
authors.lastname: Ghosh
authors.forename: Jason A
authors.initials: JA
authors.lastname: Tourville
mesh_terms: D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology; D003198:Computer Simulation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology; D013060:Speech / Q000502:physiology*; D009435:Synaptic Transmission