X-ray powder diffraction patterns for certain beta-lactam, tetracycline and macrolide antibiotic drugs.
X-ray powder diffraction (XRD) data for eight beta-lactam viz., ampicillin sodium, ampicillin trihydrate, penicillin G procaine, benzathine penicillin, benzyl penicillin sodium, cefalexin, cefotaxime sodium and ceftriaxone sodium; three tetracyclines viz., doxycycline hydrochloride, oxytetracycline dihydrate and tetracycline hydrochloride; and two macrolide viz., azithromycin and erythromycin estolate antibiotic drugs were obtained using a powder diffractometer. The drugs were scanned from Bragg angles (2theta) of 10 degrees to 70 degrees. The obtained data were tabulated in terms of the lattice spacing (A) and relative line intensities (I/I(I)). This new information may be useful for identifying these drugs from confiscated materials, which has been frequently encountered in forensic laboratories.
Thangadurai
S
S
Department of Geology and Mining, Guindy, Chennai-32, India. kalankathanga@hotmail.com/gmail.com
Abraham
J T
JT
Srivastava
A K
AK
Moorthy
M Nataraja
MN
Shukla
S K
SK
Anjaneyulu
Y
Y
D000900:Anti-Bacterial Agents / Q000737:chemistry; D018942:Macrolides / Q000737:chemistry*; D015394:Molecular Structure; D033362:Powder Diffraction / Q000379:methods*; D013752:Tetracycline / Q000737:chemistry*; D014965:X-Rays; D047090:beta-Lactams / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D018942:Macrolides; D047090:beta-Lactams; D013752:Tetracycline