title: Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism.
abstract: 1. Strong etiological association exists between dysfunctional metabolism of brain lipids, age-related changes in the cerebral vasculature and neurodegenerative features characteristic of Alzheimer's disease (AD) brain. 2. In this short review, recent experimental evidence for these associations is further discussed below.
authors.affiliation: LSU Neuroscience Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite 8D, New Orleans, Louisiana, 70112-2272, USA. wlukiw@lsuhsc.edu
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Lukiw
authors.forename: Miguel
authors.initials: M
authors.lastname: Pappolla
authors.forename: Ricardo Palacios
authors.initials: RP
authors.lastname: Pelaez
authors.forename: Nicolas G
authors.initials: NG
authors.lastname: Bazan
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D001928:Brain Diseases, Metabolic / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*; D010084:Oxidation-Reduction
chemical_list: D008074:Lipoproteins; D002784:Cholesterol