title: Pulmonary involvement in brucellosis.
abstract: OBJECTIVE
  Pulmonary involvement is a rare manifestation of brucellosis. The aim of this study was to determine the incidence and forms of pulmonary involvement in the course of brucellosis.
  
  
  METHODS
  A prospective study was carried out in 110 patients with brucellosis. All the patients were evaluated with their pulmonary symptoms, physical examination and chest radiography. If pulmonary pathologic findings were present, patients underwent additional diagnostic evaluations including computerized tomography of the thorax and pulmonary function tests.
  
  
  RESULTS
  From 110 patients, 11 (six females and five males) were diagnosed as pulmonary brucellosis. Eight of 11 patients had pulmonary symptoms including cough, sputum and dyspnoea. Radiologic findings were parenchymal nodules, lobar pneumonia, paratracheal lymphadenopathy and pleural effusion. At the end of the treatment of brucellosis, clinical findings of pulmonary involvement were recovered in all patients except four dyspnoeic patients who had coexisting COPD. Radiological findings were normal in three and improved in four patients after 6 months of the treatment.
  
  
  CONCLUSIONS
  Pulmonary involvement is a rare event in the course of brucellosis. But especially in endemic regions, brucellosis should never be forgotten as a causative agent in patients with pulmonary symptoms.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ankara Training and Research Hospital, Dikimevi, Ankara 06340, Turkey. cigdemhatip@yahoo.com
authors.forename: Ciğdem Ataman
authors.initials: CA
authors.lastname: Hatipoglu
authors.forename: Gülden
authors.initials: G
authors.lastname: Bilgin
authors.forename: Necla
authors.initials: N
authors.lastname: Tulek
authors.forename: Uğur
authors.initials: U
authors.lastname: Kosar
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002002:Brucella / Q000302:isolation & purification; D002006:Brucellosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D004318:Doxycycline / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015994:Incidence; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D012293:Rifampin / Q000008:administration & dosage; D013307:Streptomycin / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline; D012293:Rifampin; D013307:Streptomycin