title: Pattern-reversal visual evoked potentials in patients with newly diagnosed epilepsy.
abstract: OBJECTIVE
  The possible occurrence of evoked potential (EP) abnormalities in patients with newly diagnosed epilepsy has been little investigated. The main purpose of the present study was to investigate possible changes in pattern-reversal visual evoked potential (P-VEP) responses in newly diagnosed epilepsy patients.
  
  
  METHODS
  By using P-VEPs, latency values of the N75 and P100 together with amplitude values of P100 were recorded in newly diagnosed idiopathic epilepsy patients. The patients comprised two groups; nonphotosensitive (non-PS), and photosensitive (PS) patients.
  
  
  RESULTS
  Shortened N75 and normal P100 latencies of the P-VEP with higher than normal P100 amplitudes were detected in PS patients. In non-PS patients, N75 latencies of the P-VEPs were unaffected; however, P100 latencies were prolonged, and P100 amplitudes were unchanged.
  
  
  CONCLUSIONS
  P-VEPs are different from those of controls in previously untreated idiopathic epilepsy patients. Results also indicate different P-VEP features in patients with and without photoparoxysmal responses. The changes might be the result of a disorder of one or more neurotransmitters or subtle morphologic damage such as microdysgenesis.
authors.affiliation: Department of Neurology, Meram Faculty of Medicine, Selçuk University, Konya, Turkey. bogenc@mynet.com.tr
authors.forename: Bülent O
authors.initials: BO
authors.lastname: Genç
authors.forename: Emine
authors.initials: E
authors.lastname: Genç
authors.forename: Figen
authors.initials: F
authors.lastname: Güney
authors.forename: Nurhan
authors.initials: N
authors.lastname: Ilhan
mesh_terms: D000293:Adolescent; D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D020195:Epilepsy, Reflex / Q000175:diagnosis / Q000503:physiopathology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology / Q000503:physiopathology