title: [The clinical and pharmacokinetic features of lymphotropic therapy in patients with new-onset pulmonary tuberculosis].
abstract: Regional lymphotropic therapy used in complex treatment of patients with new-onset pulmonary tuberculosis enhances its efficiency. It is well tolerated by patients and easy-to-use. The pharmacokinetic feature of isoniazid during its lymphotropic administration is its shorter elimination half-life, decreased total clearance, and a larger area under the pharmacokinetic curve.
authors.forename: V N
authors.initials: VN
authors.lastname: Priakhina
authors.forename: M A
authors.initials: MA
authors.lastname: Kolpakov
authors.forename: A R
authors.initials: AR
authors.lastname: Kolpakov
authors.forename: T V
authors.initials: TV
authors.lastname: Zyrianova
authors.forename: O G
authors.initials: OG
authors.lastname: Mokhina
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D008198:Lymph Nodes / Q000378:metabolism*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid