Temporomandibular joint destruction in mucolipidosis type III necessitating gastrostomy insertion.
Mucolipidosis III is a genetically heterogeneous lysosomal disorder characterised by progressive symptoms and signs, the commonest being skeletal pain due to bony destruction. We describe a patient who developed severe destruction of the temporomandibular joints leading to difficulties with speech and feeding, necessitating gastrostomy insertion.


CONCLUSIONS
Temporomandibular joint involvement has not been previously reported in mucolipidosis III.
Zolkipli
Zarzuela
Z
Metabolic Unit, Great Ormond Street Hospital, London, UK.
Noimark
Lee
L
Cleary
Maureen A
MA
Owens
Cathy
C
Vellodi
Ashok
A
D000293:Adolescent; D005260:Female; D005774:Gastrostomy; D006801:Humans; D009081:Mucolipidoses / Q000150:complications*; D013705:Temporomandibular Joint Disorders / Q000209:etiology* / Q000503:physiopathology