MPO-ANCA-associated pseudovasculitis in cardiac myxoma.
We describe a case of cardiac myxoma whose clinical presentation mimicked that of polyarteritis nodosa. The serum levels of MPO-ANCA and IL-6 were elevated on laboratory investigation and normalized after the removal of the tumor. We suggest that a 'true' vasculitic mechanism contributes to the pathogenesis of pseudovasculitis in cardiac myxoma.
Nishio
Y
Y
Department of Neurology, Jikei University Kashiwa Hospital, Kashiwa, Japan. nishiou@mail.tains.tohoku.ac.jp
Ito
Y
Y
Iguchi
Y
Y
Sato
H
H
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000378:metabolism*; D001323:Autoantibodies / Q000032:analysis; D016179:Granulocyte Colony-Stimulating Factor; D006338:Heart Neoplasms / Q000276:immunology* / Q000503:physiopathology; D016298:Hematopoietic Cell Growth Factors / Q000378:metabolism*; D006801:Humans; D007377:Interleukin-3; D015850:Interleukin-6 / Q000378:metabolism*; D008297:Male; D009000:Monocytes / Q000473:pathology; D009232:Myxoma / Q000276:immunology* / Q000503:physiopathology; D009504:Neutrophils / Q000473:pathology; D009195:Peroxidase / Q000276:immunology*; D011993:Recombinant Fusion Proteins / Q000378:metabolism*; D011994:Recombinant Proteins; D014657:Vasculitis / Q000175:diagnosis* / Q000209:etiology
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D016298:Hematopoietic Cell Growth Factors; D007377:Interleukin-3; D015850:Interleukin-6; D011993:Recombinant Fusion Proteins; D011994:Recombinant Proteins; C404145:myelopoietin; D016179:Granulocyte Colony-Stimulating Factor; D009195:Peroxidase