[Biochemical analysis of the vitreous body of the eye in post-mortem diagnosis of diabetic coma].
The biochemical test of the vitreous body (VB) may be used in post-mortem diagnosis of diabetes mellitus and diabetic coma. Concentrations of glucose, lactate, keton bodies in the VB of the eye do not depend on duration of post-mortem period. Methods of diagnosis of hyperglycemic, hypoglycemic and ketoacidotic comas in the postmortem period are proposed. VB glucose over 17 mmol/l is a specific marker indicating death due to diabetic coma with hyperglycemia. Blood lactate under 16 mmol/l and glucose absence in the VB specifically mark death of hypoglycemic coma. In death of diabetic coma with ketoacidosis, a sharp rise in the level of VB ketonic bodies was observed.
Terekhina
N A
NA
Akimov
P A
PA
D001671:Biochemistry / Q000379:methods*; D001786:Blood Glucose / Q000032:analysis; D003926:Diabetic Coma / Q000175:diagnosis / Q000473:pathology*; D005947:Glucose / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006029:Glycosuria / Q000175:diagnosis; D006801:Humans; D007773:Lactates / Q000032:analysis / Q000097:blood; D011180:Postmortem Changes; D014822:Vitreous Body / Q000737:chemistry*
D001786:Blood Glucose; D005947:Glucose; D006442:Glycated Hemoglobin; D007773:Lactates