title: [Herbal supplements in sports: use and abuse].
abstract: The use of natural supplements, included herbal supplements, by athletes has become an habit which often lacks any valid scientific rationale. It appears evident that this habit may entail health risks (including more or less serious adverse effects), consequent either: 1) to the pharmacodynamic effects of the drugs at high doses; or 2) to the occurrence of accumulation especially when their administration is not justified by a reduced synthesis or an increased demand; or 3) to the occurrence of intolerance; or, finally, 4) to the presence of unlabelled ingredients. The abuse of this kind of products always entails risks to the consumer, not only to the elite athlete, that can incur an adverse analytical finding on the occasion of anti-doping tests, but also to the amateur sportsman, for the possible occurrence of adverse drug reactions (ADR).
authors.affiliation: Dipartimento di Fisiologia Umana e Farmacologia Vittorio Erspamer, Universita degli Studi La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy. luciano.caprino@uniroma1.it
authors.forename: Luciano
authors.initials: L
authors.lastname: Caprino
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Braganò
authors.forename: Francesco
authors.initials: F
authors.lastname: Botrè
mesh_terms: D000222:Adaptation, Physiological; D024803:Biomedical Enhancement / Q000592:standards; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D019587:Dietary Supplements / Q000009:adverse effects; D004300:Doping in Sports / Q000331:legislation & jurisprudence; D062787:Drug Overdose; D029001:Herbal Medicine / Q000331:legislation & jurisprudence / Q000592:standards; D006706:Homeostasis; D006801:Humans; D007558:Italy; D028321:Plant Preparations / Q000009:adverse effects* / Q000494:pharmacology / Q000592:standards / Q000627:therapeutic use; D013178:Sports Medicine / Q000331:legislation & jurisprudence / Q000592:standards; D013312:Stress, Physiological / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000697:Central Nervous System Stimulants; D028321:Plant Preparations