[Features of subjects purchasing Sildenafil at community pharmacies in Concepción, Chile].
BACKGROUND
Erectile dysfunction is a public health problem. Millions of men worldwide experience this condition, affecting their quality of life. Sildenafil, a phosphodiesterase type 5 inhibitor, is the treatment of choice for erectile dysfunction.


OBJECTIVE
To study the characteristics of Sildenafil use among costumers of community pharmacies in Concepcion Chile.


METHODS
A structured interview about Sildenafil use was applied to subjects purchasing the drug in community pharmacies and that consented to participate.


RESULTS
One hundred thirty eight males were studied. Forty six percent of patients were fifty years old or older. Most (47.1%) used Sildenafil for one year or more and 60.5% had no adverse events. Among those experiencing side effects, headache was experienced by 38.9%, flushing by 16.6% and gastrointestinal effects by 16.7%. Ninety percent of patients had a good evaluation of the drug in terms of benefits and tolerance. Thirty two percent of the subjects, had diseases associated to erectile dysfunction. Among these, 45% had diabetes mellitus, 29.5% had hypertension, and 18.2% had prostatic diseases. In 54% of cases, the drug was prescribed by a physician. Twenty two percent of patients experienced changes in the effect of the drug when it was simultaneously used with other drugs or meals. Thirty four percent of patients used other drugs. Among these, 43.3% were using antihypertensives, and 26.7% were using antidiabetic drugs.


CONCLUSIONS
Considering the elevated age and the number of associated disease of patients using Sildenafil, the use of the drug under medical prescription must be emphasized to avoid untoward effects.
Mennickent
Sigrid
S
Departamento de Bromatología, Nutrición y Dietética, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile. smennick@udec.cl
Zurita
Libna
L
Vega
Mario
M
Villegas
Guiljardy
G
D000328:Adult; D000367:Age Factors; D002677:Chile; D003157:Community Pharmacy Services; D004347:Drug Interactions; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use*; D019338:Polypharmacy; D011687:Purines; D012307:Risk Factors; D000068677:Sildenafil Citrate; D013450:Sulfones; D014665:Vasodilator Agents / Q000009:adverse effects / Q000627:therapeutic use*
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate