[A case of drug-induced pneumonitis associated with chinese herbal drugs and valsartan].
A 70-year-old man was admitted with a chief complaint of dyspnea. Chest X-ray images showed diffuse infiltrative shadows in both lungs. A chest CT scan showed diffuse non-segmental consolidation with an air bronchogram, ground-glass opacity, and possible traction bronchiectasis. The number of lymphocytes was abnormally high in the bronchoalveolar lavage fluid (BALF), and examination of a transbronchial lung biopsy specimen revealed Masson's body and bronchiolitis. Microorganisms were not present in the BALF. Drug-induced pneumonitis, caused by the Chinese herbal drug saiko-ka-ryukotsu-borei-to or valsartan or both, which he had been taking for about 3 months, was diagnosed. The patient's symptoms and the pulmonary infiltrates seen on chest radiograph diminished after these drugs were discontinued and oral prednisolone was administered.
Tokunaga
Takanari
T
Department of Medicine, Hanyu General Hospital.
D000368:Aged; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic; D013777:Tetrazoles / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D014633:Valine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D000068756:Valsartan
D004365:Drugs, Chinese Herbal; D013777:Tetrazoles; C095444:saiko-ka-ryukotsu-borei-to; D000068756:Valsartan; D014633:Valine