Malignant fibrous histiocytoma of the vulva: a case report.
BACKGROUND
Primary sarcomas of the vulva are rare tumors that account for 1.8-3% of all vulvar malignancies. Malignant fibrous histiocytoma occurs infrequently on the vulva but nonetheless is the second most frequent sarcoma of this region. The purpose of this report is to review the diagnosis and therapy of this exceedingly rare tumor.


METHODS
A 72-year-old woman was presented with a vulvar mass that was ultimately found to be a vulvar malignant fibrous histiocytoma. After surgical excision and 9 months of initial diagnosis, she returned with rapid localized progression and pulmonary metastases.


CONCLUSIONS
Malignant fibrous histiocytoma arising in the vulva represents an example of vulvar sarcomas. Since the diagnostic criteria and natural history of this tumor still remain poorly defined, further case studies may be helpful to elucidate these issues as well as the optimal therapeutic approach of this heterogeneous group of malignancies.
Vural
Birol
B
Department of Obstetrics and Gynecology, At Kocaeli University School of Medicine, Tüpraş Sitesi, Güney Mahallesi, 7. Sokak, No.: 20, Kat:2, Körfez, Kocaeli, Turkey.
Ozkan
Sebiha
S
Yildiz
Kürşat
K
Corakçi
Aydin
A
Gürbüz
Yeşim
Y
D000368:Aged; D005260:Female; D051677:Histiocytoma, Malignant Fibrous / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D014846:Vulvar Neoplasms / Q000473:pathology*