title: Reversible CSF cyst related to a functioning ventriculo-peritoneal shunt.
abstract: Although the occurrence of CSF oedema and cyst has been described in presence of a blocked ventriculoperitoneal shunt, especially distal end block, its occurrence in presence of a well functioning shunt has not been described so far. We report a case where a 51-year old lady developed an insidious onset and gradually progressive CSF cyst without any clinical or radiological feature of shunt block over a period of about 2 years. The changes started about 6 months after a course of radiation therapy for an extensive residual supra and infratentorial meningioma. Following surgery, where the cyst was punctured and a new ventricular catheter was inserted, despite well functioning upper and lower end, the cyst gradually disappeared. We review the literature and hypothesize that the radiation-induced changes were responsible for initiation and progression of the cyst.
authors.affiliation: Department of Neurosurgery, Wessex Neurological Centre, Southampton General Hospital, UK.
authors.forename: G V
authors.initials: GV
authors.lastname: Vajramani
authors.forename: K
authors.initials: K
authors.lastname: Fugleholm
mesh_terms: D002555:Cerebrospinal Fluid / Q000502:physiology; D003560:Cysts / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D004388:Dura Mater / Q000473:pathology / Q000503:physiopathology / Q000528:radiation effects; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000532:radiotherapy*; D008579:Meningioma / Q000532:radiotherapy*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D011878:Radiotherapy / Q000009:adverse effects*; D019292:Skull Base Neoplasms / Q000532:radiotherapy; D013687:Telencephalon / Q000473:pathology / Q000503:physiopathology; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*