Synthesis and cross-coupling reactions of substituted 5-triflyloxyindoles.
N-arylsulfonyl quinone monoimines undergo smooth cycloadditions in a [4+2] sense to yield the expected cycloadducts. The crude cycloadducts, when subjected to a short series of simple transformations, produce synthetically useful quantities of 5-triflyloxyindoles in excellent overall yields. Such compounds are excellent participants in cross-coupling chemistry.
England
Dylan B
DB
Department of Chemistry, The University of Western Ontario, London, Ontario, Canada, N6A 5B7.
Kerr
Michael A
MA