title: Oral lichen planus in childhood.
abstract: Oral lichen planus is rare in childhood, and only a few reports on this subject have appeared in the literature. Our objective was to report individual cases of oral lichen planus in childhood from our practice and to review the literature on this subject. We recruited patients younger than 18 years with oral lichen planus and documented several clinical aspects, the histopathology, patch tests, and blood examination findings. Three patients from about 10,000 dermatology patients younger than 18 years seen from 1994 to 2003 were included. Of these three, an Asian girl aged 11 years had an asymptomatic, hyperkeratotic variant of oral lichen planus, which disappeared without any treatment after 1 year. An Asian boy aged 16 years had an erosive oral lichen planus with severe pain, which healed after intensive local and systemic treatment in 2 years. A Caucasian girl aged 14 years had a hyperkeratotic variant with a little soreness, which disappeared with local treatment after 3 months. Our findings indicated that oral lichen planus in childhood is rare and therefore at present it is not possible to draw firm conclusions considering its nature and etiology. Oral lichen planus in childhood seems to occur preferentially in those of Asian race. The clinical features resemble those of oral lichen planus in adults. However, generally the prognosis of oral lichen planus in childhood seems to be more favorable than in adults.
authors.affiliation: Department of Dermatology, Albert Schweitzer Hospital, Albert, Schweitzerplaats, The Netherlands. r.laeijendecker@asz.nl
authors.forename: Ronald
authors.initials: R
authors.lastname: Laeijendecker
authors.forename: Theodoor
authors.initials: T
authors.lastname: Van Joost
authors.forename: Bhupendra
authors.initials: B
authors.lastname: Tank
authors.forename: Arnold P
authors.initials: AP
authors.lastname: Oranje
authors.forename: H A Martino
authors.initials: HA
authors.lastname: Neumann
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D044466:Asian People; D016572:Cyclosporine / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017676:Lichen Planus, Oral / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D009426:Netherlands; D018704:Orthodontic Retainers; D012189:Retrospective Studies; D014212:Tretinoin / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D003879:Dermatologic Agents; D014212:Tretinoin; D016572:Cyclosporine