title: [Outcomes of transplantation from living renal donor].
abstract: Living donors represent 30% of our kidneys for renal transplantation. Laparoscopic nephrectomy is the best surgical procedure to obtain them due to its clear advantages such as low morbidity, less blood supply and donor time in hospital. From March 2002 to August 2004 we performed 50 laparoscopic nephrectomies for renal transplantation. Kidneys were transplanted to recipients receiving tacrolimus 0.1 mg/kg/bid, mycophenolate mofetil 1 g/bid and prednisone 0.5-1 mg/kg/day p.o 48 hours before transplantation. Mean time for surgery was 170 minutes (120-260), warm ischaemia time 3.1 minutes (1.5-10) and cold ischaemia time 1.27 hours (0.85-4). Mean bleeding was 270 cc (100-900) and donor time in hospital 5.5 days (3-9). Four cases required conversion of the laparoscopic procedure to open surgery because of bleeding. 72 hours post-transplant mean plasmatic creatinine was 170 micromol/l. None of the patients suffered delayed graft function. 18% presented acute rejection. Survival of donor and recipient was 100% at 1 year and graft survival was 94% at 1 year (kidney losses were due to acute rejection, severe acute pancreatitis and surgical problem).
authors.affiliation: Unidad de Trasplante Renal, Servicio de Nefrología, Fundació Puigvert, Barcelona. iguirado@fundacio-puigvert.es
authors.forename: Ll
authors.initials: L
authors.lastname: Guirado
authors.forename: J M
authors.initials: JM
authors.lastname: Díaz
authors.forename: C
authors.initials: C
authors.lastname: Facundo
authors.forename: A
authors.initials: A
authors.lastname: Alcaraz
authors.forename: A
authors.initials: A
authors.lastname: Rosales
authors.forename: R
authors.initials: R
authors.lastname: Solà
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D002102:Cadaver; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016030:Kidney Transplantation; D010535:Laparoscopy; D007902:Length of Stay; D019520:Living Donors; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D009392:Nephrectomy; D011241:Prednisone / Q000008:administration & dosage; D016019:Survival Analysis; D016559:Tacrolimus / Q000008:administration & dosage; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D011241:Prednisone; D016559:Tacrolimus