A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine.
A novel ANRORC mechanism in the reaction of 1-(2,4-dinitrobenzenesulfonyl)inosines with amines has allowed the preparation of 1-alkyladenosines and [1-15N]adenosines in a straightforward way from inosines.
Terrazas
Montserrat
M
Departament de Química Orgànica, Universitat de Barcelona, Av. Diagonal 647, 08028, Barcelona, Spain.
Ariza
Xavier
X
Farràs
Jaume
J
Vilarrasa
Jaume
J
D000241:Adenosine / Q000138:chemical synthesis*; D007288:Inosine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009587:Nitrogen Isotopes
D009587:Nitrogen Isotopes; D007288:Inosine; D000241:Adenosine