Progressive neuropsychiatric problems following institution of highly active antiretroviral therapy.
A 31 year old HIV infected woman developed neuropsychiatric problems soon after starting highly active antiretroviral therapy (HAART). Despite modifying and subsequently stopping HAART her condition progressively worsened. Cranial magnetic resonance imaging revealed multiple areas of abnormal signal suggestive of either a vasculitis or demyelination.
Miller
R F
RF
Patrick Manson Unit, University College London Hospital, and Mortimer Market Centre, London WC1E 6AU, UK. rmiller@gum.ucl.ac.uk
Dave
S S
SS
Tang
J W
JW
Shaw
P J
PJ
Jäger
H R
HR
Wilkins
E G L
EG
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D001523:Mental Disorders / Q000139:chemically induced*; D014385:Tuberculosis, Gastrointestinal / Q000175:diagnosis / Q000188:drug therapy; D020293:Vasculitis, Central Nervous System / Q000139:chemically induced* / Q000175:diagnosis