title: [Expression of extracellular matrix metalloproteinase inducer during normal pregnancy].
abstract: OBJECTIVE
  To study the expression of extracellular matrix metalloproteinase inducer (EMMPRIN) during normal pregnancy.
  
  
  METHODS
  The expression of EMMPRIN was studied with immunohistochemistry in normal pregnancy.
  
  
  RESULTS
  The expression of EMMPRIN was obvious, and appeared mainly on membrane of cytotrophoblast, syncytiotrophoblast, cytotrophoblast column of the villi of gestational weeks 6 to 9, mid-term and term placenta and extravillous cytotrophoblast of deciduas of mid-term and term placenta. The expression reached a peak level at gestational week 6 and gradually decreased from week 7 and stabilized to a low level at mid-term and term placenta when the expression of extravillous cytotrophoblast of deciduas was increased.
  
  
  CONCLUSIONS
  EMMPRIN may be an important factor for implantation during early pregnancy and participate in maintaining gestation during mid-term and term pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, the Second Hospital of China Medical University, Shenyang 110003, China.
authors.forename: Yong-qing
authors.initials: YQ
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Shang
authors.forename: Yan-ling
authors.initials: YL
authors.lastname: Wang
mesh_terms: D051926:Basigin / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy / Q000378:metabolism*
chemical_list: C497886:BSG protein, human; D051926:Basigin