[Tubulointerstitial nephritis with uveitis (TINU) syndrome].
Authors present an 11-year old girl with non-specific clinical symptoms with increase of inflammatory indices and acute non-oliguric renal failure: creatinine clearance - 55 ml/min/1.73 m2. An anterior uveitis was observed after 7 weeks of illness. Diagnosis of tubulointerstitial nephritis with uveitis (TINU) was confirmed by interstitial infiltrate (lymphocytes, neutrophils, eosinophils) and interstitial fibrosis in renal biopsy. Steroid therapy was given for 7 months. Uveitis without kidney involvement relapsed 1 month after discontinuation of steroid therapy. The full recovery of uveitis was achieved after the treatment with topical steroids. After 3 years, the illness remains still in remission.
Szymanik-Grzelak
Hanna
H
Z Katedry i Kliniki Pediatrii i Nefrologii Akademii Medycznej w Warszawie.
Roszkowska-Blaim
Maria
M
Sekowska
Renata
R
Kamińska
Anna
A
Weglarska
Jolanta
J
D058186:Acute Kidney Injury / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D002648:Child; D005260:Female; D006801:Humans; D009395:Nephritis, Interstitial / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D013577:Syndrome; D013997:Time Factors; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000150:complications / Q000175:diagnosis / Q000628:therapy
D000305:Adrenal Cortex Hormones