title: The impact of a new CPR assist device on rate of return of spontaneous circulation in out-of-hospital cardiac arrest.
abstract: OBJECTIVE
  The San Francisco Fire Department deployed an automated, load-distributing-band chest compression device (AutoPulse, Revivant Corporation) to evaluate its function in a large urban emergency medical services (EMS) service. A retrospective chart review was undertaken to determine whether the AutoPulse had altered short-term patient outcome, specifically, return of spontaneous circulation (ROSC).
  
  
  METHODS
  AutoPulse cardiopulmonary resuscitation (A-CPR) was used by paramedic captains responding to adult cardiac arrests with an average +/-SD response time of 15 +/- 5 minutes. The primary endpoint was patient arrival to an emergency department with measurable spontaneous pulses. The manual CPR comparison group was case-matched for age, gender, initial presenting electrocardiogram rhythm, and the number of doses of Advanced Cardiac Life Support medications as a proxy for treatment time. Matching was performed by an investigator blinded to outcome and treatment group.
  
  
  RESULTS
  Sixty-nine AutoPulse uses were matched to 93 manual-CPR-only cases. A-CPR showed improvement in the primary outcome when compared with manual CPR with any presenting rhythm (A-CPR 39%, manual 29%, p = 0.003). When patients were classified by first presenting rhythm, shockable rhythms showed no difference in outcome (A-CPR 44%, manual 50%, p = 0.340). Outcome was improved with A-CPR in initial presenting asystole and approached significance with pulseless electrical activity (PEA)(asystole: A-CPR 37%, manual 22%, p = 0.008; PEA: A-CPR 38%, manual 23%, p = 0.079).
  
  
  CONCLUSIONS
  The AutoPulse may improve the overall likelihood of sustained ROSC and may particularly benefit patients with nonshockable rhythms. A prospective randomized trial comparing the AutoPulse with manual CPR in the setting of out-of-hospital sudden cardiac arrest is under way.
authors.affiliation: San Francisco Fire Department, San Francisco, California 94107, USA. michael.casner@sfgov.org
authors.forename: Michael
authors.initials: M
authors.lastname: Casner
authors.forename: David
authors.initials: D
authors.lastname: Andersen
authors.forename: S Marshal
authors.initials: SM
authors.lastname: Isaacs
mesh_terms: D000328:Adult; D022561:Advanced Cardiac Life Support / Q000295:instrumentation* / Q000379:methods; D000368:Aged; D000369:Aged, 80 and over; D016887:Cardiopulmonary Resuscitation / Q000295:instrumentation* / Q000379:methods; D016022:Case-Control Studies; D004632:Emergency Medical Services / Q000379:methods*; D004869:Equipment Safety; D005260:Female; D006323:Heart Arrest / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy*; D006336:Heart Massage / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D012189:Retrospective Studies; D018570:Risk Assessment; D012495:San Francisco; D012680:Sensitivity and Specificity; D015996:Survival Rate; D016896:Treatment Outcome