title: Chorea associated with thyroxine replacement therapy.
abstract: Chorea is an uncommonly reported manifestation of hyperthyroidism. We report the first description of generalized chorea due to iatrogenic thyrotoxicosis and propose that the movement disorder is due to a direct effect of thyroxine on the basal ganglia rather than being an autoimmune phenomenon.
authors.affiliation: Department of Medicine, Hammersmith Hospital, London, UK. j.isaacs@prion.ucl.ac.uk
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Isaacs
authors.forename: James
authors.initials: J
authors.lastname: Rakshi
authors.forename: Richard
authors.initials: R
authors.lastname: Baker
authors.forename: David J
authors.initials: DJ
authors.lastname: Brooks
authors.forename: Anthony N
authors.initials: AN
authors.lastname: Warrens
mesh_terms: D000368:Aged; D002819:Chorea / Q000209:etiology*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000601:surgery; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000009:adverse effects*
chemical_list: D013974:Thyroxine