Post-transplantation growth among pediatric recipients of liver transplantation.
Improving a patient's quality-of-life (QOL) post-liver transplantation is of great importance. An aspect of improved QOL is the restoration of normal growth patterns in pediatric patients. To describe the post-transplantation growth patterns of 72 children included in the National Institute of Diabetes and Digestive and Kidney Diseases - Liver Transplantation Database (NIDDK-LTD), multilevel models were used, according to which children who waited more than a year for transplantation were smaller, compared with age and sex matched peers, at transplantation than children who waited less than a year while children who were growth retarded at transplantation experienced a larger yearly comparison height increase than children who were not growth retarded. The analysis also showed that boys older than 2 yr and younger than 13 yr at transplantation and girls older than 2 yr and younger than 11 yr at transplantation were significantly less growth retarded at transplantation than boys and girls under the age of 2 yr at transplantation.
Evans
Idris V R
IV
University of Pittsburgh, Graduate School of Public Health, PA 15261, USA. evansi@edc.pitt.edu
Belle
Steven H
SH
Wei
Yuling
Y
Penovich
Carol
C
Ruppert
Kris
K
Detre
Katherine M
KM
D000293:Adolescent; D001827:Body Height; D016009:Chi-Square Distribution; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007165:Immunosuppression Therapy; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D012307:Risk Factors; D018709:Statistics, Nonparametric; D014850:Waiting Lists