title: Acoustic radiation force impulse imaging of myocardial radiofrequency ablation: initial in vivo results.
abstract: Acoustic radiation force impulse (ARFI) imaging techniques were used to monitor radiofrequency (RF) ablation of ovine cardiac tissue in vivo. Additionally, ARFI M-mode imaging methods were used to interrogate both healthy and ablated regions of myocardial tissue. Although induced cardiac lesions were not visualized well in conventional B-mode images, ARFI images of ablation procedures allowed determination of lesion location, shape, and relative size through time. The ARFI M-mode images were capable of distinguishing differences in behavior through the cardiac cycle between healthy and damaged tissue regions. As conventional sonography is often used to guide ablation catheters, ARFI imaging, which requires no additional equipment, may be a convenient modality for monitoring lesion formation in vivo.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC, USA. brian.fahey@duke.edu
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Fahey
authors.forename: Kathryn R
authors.initials: KR
authors.lastname: Nightingale
authors.forename: Stephen A
authors.initials: SA
authors.lastname: McAleavey
authors.forename: Mark L
authors.initials: ML
authors.lastname: Palmeri
authors.forename: Patrick D
authors.initials: PD
authors.lastname: Wolf
authors.forename: Gregg E
authors.initials: GE
authors.lastname: Trahey
mesh_terms: D000818:Animals; D017115:Catheter Ablation / Q000379:methods*; D004452:Echocardiography / Q000379:methods*; D005240:Feasibility Studies; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000601:surgery*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D010865:Pilot Projects; D012756:Sheep; D013314:Stress, Mechanical; D025321:Surgery, Computer-Assisted / Q000379:methods*