Endocrine manifestations of craniopharyngioma.
BACKGROUND
Due to the proximity of craniopharyngiomas to the hypothalamus and pituitary gland, most children and adolescents presenting with these tumors will exhibit significant endocrine dysfunction. After treatment, these impairments can become a major cause of morbidity and mortality.


METHODS
The postoperative course of children undergoing surgery for craniopharyngioma is reviewed.


CONCLUSIONS
Even if hormone levels seem to be adequate in the short term after treatment, deficiencies may develop over years and need to be monitored closely.
Halac
Isil
I
Division of Endocrinology, Children's Memorial Hospital, 2300 Children's Plaza, P.O. Box # 54, Chicago, IL 60614, USA.
Zimmerman
Donald
D
D000324:Adrenocorticotropic Hormone / Q000172:deficiency; D001835:Body Weight / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000503:physiopathology* / Q000601:surgery; D004703:Endocrine System / Q000503:physiopathology*; D004700:Endocrine System Diseases / Q000209:etiology*; D005640:Follicle Stimulating Hormone / Q000172:deficiency; D006801:Humans; D007986:Luteinizing Hormone / Q000172:deficiency; D009481:Neurophysins / Q000378:metabolism; D010911:Pituitary Neoplasms / Q000503:physiopathology* / Q000601:surgery; D011183:Postoperative Complications; D011498:Protein Precursors / Q000378:metabolism; D013972:Thyrotropin / Q000378:metabolism; D014667:Vasopressins / Q000378:metabolism
C438657:AVP protein, human; D009481:Neurophysins; D011498:Protein Precursors; D014667:Vasopressins; D000324:Adrenocorticotropic Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin