[The clinical and immunological manifestations of infiltrative pulmonary tuberculosis under natural zinc deficiency].
Patients with infiltrative pulmonary tuberculosis who lived in zinc-deficient areas (the level of mobile zinc in the soil is < 0.1 mg/kg, and its dietary level is 9.1 mg/day) were found to have a significant depression of the T-cell link of the immunity system along with enhanced activation apoptosis and decreased phagocytic activity of neutrophils. The detected immunological disorders determine a sluggish and asymptomatic onset and an unfavorable course of the disease with a predominance of destructive and bacillary forms.
Karzakova
L M
LM
Mokhireva
L V
LV
Elenkina
Zh B
ZhB
Suslikov
V L
VL
D000328:Adult; D015703:Antigens, CD / Q000097:blood* / Q000276:immunology; D005260:Female; D006684:HLA-DR Antigens / Q000097:blood* / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D017254:Leukemic Infiltration; D008297:Male; D020556:Neutrophil Infiltration / Q000502:physiology*; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000276:immunology*; D015032:Zinc / Q000172:deficiency
D015703:Antigens, CD; D006684:HLA-DR Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D015032:Zinc