Structure of a cognitive ability battery among HIV+ intravenous drug users evaluated in a study of medication adherence.
Several cognitive domains are important determinants of medication adherence in individuals treated for HIV infection. This study investigated via confirmatory factor analysis the structure of cognitive abilities in a group of HIV+ intravenous drug users administered a battery of neuropsychological measures. It also investigated the relation of dimensions of cognition to demographic, mood, and immune system status measures. The hypothesized model of cognitive abilities fit the data well. Path analyses showed that demographic variables, mood, and measures of immune status were related to cognitive ability dimensions. This model may be useful in guiding selection of assessment instruments in future studies.
Ownby
Raymond L
RL
Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine Miami, FL 33140, USA. rownby@med.miami.edu
Kumar
Mahendra
M
Waldrop-Valverde
Drenna
D
D000293:Adolescent; D000328:Adult; D044966:Anti-Retroviral Agents / Q000008:administration & dosage; D018791:CD4 Lymphocyte Count; D003072:Cognition Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D004185:Disability Evaluation; D018450:Disease Progression; D004522:Educational Status; D005163:Factor Analysis, Statistical; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000523:psychology*; D006304:Health Status; D006801:Humans; D007107:Immune System / Q000503:physiopathology; D015233:Models, Statistical; D009483:Neuropsychological Tests; D010349:Patient Compliance / Q000523:psychology*; D011597:Psychomotor Performance / Q000502:physiology; D019966:Substance-Related Disorders / Q000150:complications* / Q000523:psychology*; D014705:Verbal Behavior / Q000502:physiology; D019562:Viral Load
D044966:Anti-Retroviral Agents