Trends of HIV-1 seroincidence among HIV-1 sentinel surveillance groups in Cambodia, 1999-2002.
This study reports trends in HIV-1 incidence in Cambodia among different target groups in the HIV-1 Sentinel Surveillance Program in 1999, 2000, and 2002, using the newly developed IgG capture BED-enzyme (HIV subtypes B, E and D) immunoassay (BED-CEIA). HIV-1-positive specimens (n=3599) from 4 sentinel groups in the HIV-1 Sentinel Surveillance Program from 1999 to 2002-brothel-based commercial sex workers (CSWs), indirect commercial sex workers (IDSWs), police, and women attending antenatal clinics (ANCs)-were tested using the BED-CEIA. Annualized incidence rates were calculated for each group and each geographic region. Between 1999 and 2002, incidence rates declined among CSWs from 13.9% to 6.45%, among IDSWs from 5.92% to 2.87%, and among police from 1.58% to 0.26%. In the ANC group, the incidence remained stable, 0.64% in 1999, 1.11% in 2000, and 0.59% in 2002. However, there was an increasing trend among ANCs in rural areas, from 0.12 to 0.89%. In conclusion, HIV-1 incidence among CSWs, IDSWs, and police has declined between 1999 and 2002; however, the incidence has not declined in the ANC group.
Saphonn
Vonthanak
V
National Center for HIV/AIDS, Dermatology and STDs, Phnom Penh, Cambodia and the Department of Epidemiology, University of California School of Public Health, Los Angeles, CA 90095-1772, USA.
Parekh
Bharat S
BS
Dobbs
Trudy
T
Mean
ChiVun
C
Bun
Leng Hor
LH
Ly
Sun Penh
SP
Heng
Sopheab
S
Detels
Roger
R
D000293:Adolescent; D000328:Adult; D002160:Cambodia / Q000453:epidemiology; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016495:Police; D011247:Pregnancy; D018571:Sentinel Surveillance; D011477:Sex Work