[Reversible brain damage following acute poisoning with an organic solvent determined by magnetic resonance].
BACKGROUND
Acute exposure to the effects of volatile solvents is characterized by the abrupt onset of symptoms and signs of poisoning, and relatively fast recovery in the majority of cases.


METHODS
We report a 24-year-old patient with an acute, accidental poisoning with a mixture of volatile organic solvents (most probably toluene, styrene and xylene), which led to the development of upward gaze paresis, diplopia, hemiparesis, ataxic gate, and the late onset truncal ataxia episodes. After 6 weeks, he recovered completely, while his extensive brain MRI lesions in the caudate nuclei, laterobasal putaminal regions, bilateral anterior insular cortex, central midbrain tegmental area) withdrew completely after 4 months.


CONCLUSIONS
Acute toxic encephalopathy should be a part of the differential diagnosis in any patient with acute neurobehavioral and neurological deficit.
Dujmović
Irena
I
Klinicki centar Srbije, Institut za neurologiju, Beograd, Srbija i Crna Gora. marinas@imi.bg.ac.yu
Svetel
Marina
M
Petrović
Igor
I
Stefanova
Elka
E
Koprivsek
Katarina
K
Kozić
Dusko
D
Kostić
Vladimir
V
D000208:Acute Disease; D000328:Adult; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012997:Solvents / Q000506:poisoning*
D012997:Solvents