title: Paraesophageal lymph node metastasis from prostatic adenocarcinoma in a patient with esophageal squamous carcinoma.
abstract: SUMMARY. Esophageal squamous carcinomas induce regional immune suppression in the domain of the tumor while the global immune system remains intact. We report a patient with a squamous esophageal carcinoma, who was discovered at esophagectomy to have paraesophageal lymph node metastases from a prostatic adenocarcinoma. No other sites of metastatic disease were identified. This supports the concept that regional immune suppression by esophageal squamous cancers facilitates growth of metastases in the local lymph nodes.
authors.affiliation: Cork Cancer Research Centre and Department of Surgery, Mercy University Hospital, Cork, Ireland.
authors.forename: J O
authors.initials: JO
authors.lastname: Larkin
authors.forename: C G
authors.initials: CG
authors.lastname: Collins
authors.forename: S T
authors.initials: ST
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Kalimuthu
authors.forename: J
authors.initials: J
authors.lastname: Fitzgibbon
authors.forename: G
authors.initials: G
authors.lastname: Lee
authors.forename: G C
authors.initials: GC
authors.lastname: O'Sullivan
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D016629:Esophagectomy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D009378:Neoplasms, Multiple Primary; D011471:Prostatic Neoplasms / Q000556:secondary* / Q000601:surgery; D020728:Transurethral Resection of Prostate