title: [Structural and ultrastructural changes in thrombocytes of patients with measles before admittance to the hospital and after discharge].
abstract: Thrombocytes have been studied at the admittance to the hospital of patients with measles and after their discharge using light and electron microscopy. Response of thrombocytes to antigen penetrated into the organism has been shown, however, it appears to be absolutely different before and after the treatment. Structural indices of thrombocytes were studied in their functional aspect. Obtained parameters of thrombocytes at the admittance of patients to the hospital indicate that giant forms of thrombocytes are prevailed and "biological net" is absent, while before discharge of patients the number of mature thrombocytes increases, and amount of giant forms decrease to the minimum. There appears a "biological net", playing an important role in the adsorption of the antigen. Proceeding from this, functional possibilities of thrombocytes, first of all, are directed to defense of the macroorganism from viral antigen. In its turn, measles virus having an influence on the thrombocytes can induce relieve of granules from their body, which also can seem to be the defensive reaction against the antigen.
authors.affiliation: Department of Infectious Diseases, Georgian State Medical Academy.
authors.forename: Kh N
authors.initials: KhN
authors.lastname: Bakuzanashvili
authors.forename: M V
authors.initials: MV
authors.lastname: Dzhavakhadze
mesh_terms: D000293:Adolescent; D000328:Adult; D001792:Blood Platelets / Q000648:ultrastructure*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008457:Measles / Q000097:blood* / Q000503:physiopathology*; D010343:Patient Admission; D010351:Patient Discharge; D013997:Time Factors