title: Labeling studies on the formation pathway of Nepsilon-carboxymethyllysine in maillard-type reactions.
abstract: Nepsilon-carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon-13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.
authors.affiliation: Department of Chemistry, Technical University of Munich, Lichtenbergstrasse 4, D-85748 Garching, Germany.
authors.forename: Martina
authors.initials: M
authors.lastname: Kasper
authors.forename: Peter
authors.initials: P
authors.lastname: Schieberle
mesh_terms: D002247:Carbon Isotopes; D017127:Glycation End Products, Advanced; D008239:Lysine / Q000031:analogs & derivatives* / Q000737:chemistry; D015416:Maillard Reaction; D008958:Models, Molecular
chemical_list: D002247:Carbon Isotopes; D017127:Glycation End Products, Advanced; C048496:N(6)-carboxymethyllysine; D008239:Lysine