Effect of various antibacterial preparations on the pathogenic oral flora in elderly patients fed via nasogastric tube.
Oropharyngeal colonization by pathogenic gram-negative bacilli (GNB) and Staphylococcus aureus is associated with aspiration pneumonia. Decolonization in high-risk populations may be important. We prospectively evaluated six antiseptic compounds in nasogastric tube-fed frail elderly patients; only polymixine reduced oropharyngeal colonization with GNB. None had an effect on S. aureus colonization.
Leibovitz
Arthur
A
Shmuel-Harofeh Hospital, Geriatric Medical Center, POB 2, Be'er-Ya'akov, 70350, Israel.
Carmeli
Yehuda
Y
Segal
Refael
R
D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D015169:Colony Count, Microbial; D004750:Enteral Nutrition; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006801:Humans; D007441:Intubation, Gastrointestinal; D008297:Male; D008875:Middle Aged; D009960:Oropharynx / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity
D000900:Anti-Bacterial Agents