title: [Fetal supraventricular tachyarrhythmias refractory to initial therapy].
abstract: Fetal arrhythmia is an unusual cause of admission in critical care unit. We report three cases of pregnant patients with gestational age of 27 to 32 weeks, with diagnosis of fetal sustained supraventricular tachyarrhymias; which were resistant to digoxin as first line therapy. Two fetuses had supraventricular tachycardia and were converted with flecainide in association with digoxin. A remaining hydropic fetus suffering atrial flutter with 2:1 auriculo-ventricular conduction, failed to restore sinus rhythm with digoxin alone or in association with flecainide nor amiodarone, and required premature c-section at 30a week of gestation. Due to amiodarone administration the neonate suffered transient neonatal hypothyroidism.
authors.affiliation: División Cuidados Intensivos, Clínica y Maternidad Suizo Argentina, Buenos Aires. criticalobstetric@hotmail.com
authors.forename: Eduardo
authors.initials: E
authors.lastname: Malvino
authors.forename: Maria C
authors.initials: MC
authors.lastname: Bruno
authors.forename: Juan P
authors.initials: JP
authors.lastname: Gallo
authors.forename: Juan C
authors.initials: JC
authors.lastname: Medrano
authors.forename: Daniel
authors.initials: D
authors.lastname: Ferrante
mesh_terms: D000328:Adult; D000638:Amiodarone / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004077:Digoxin / Q000627:therapeutic use; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005424:Flecainide / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011247:Pregnancy; D013617:Tachycardia, Supraventricular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D005424:Flecainide; D000638:Amiodarone