title: Antimicrobial activity of some Ganoderma species from Nigeria.
abstract: The crude n-hexane:diethyl ether, chloroform:acetone and methanol extracts of four species of Ganoderma (Ganoderma colossum (Fr.) C. F. Baker, G. resinaceum Boud., G. lucidum (cf.) (Curtis) P. Karst. and G. boninense (cf.) Pat.), from Nigeria, were tested for antimicrobial activity. The three solvent extracts of all the species of Ganoderma were active against Pseudomonas syringae and Bacillus subtilis, whereas none of the extracts were active against Cladosporium herbarum. Preliminary thin layer chromatography chemical tests on these extracts of Ganoderma showed that they contained compounds that stained blue-violet and blue or green when sprayed with anisaldehyde-sulphuric acid or Dragendorff, respectively. The profile of compounds in the extracts showed some variation among the four species.
authors.affiliation: Department of Biological Sciences, Yaba College of Technology, P. M. B 2011, Yaba, Lagos, Nigeria.
authors.forename: L N
authors.initials: LN
authors.lastname: Ofodile
authors.forename: N U
authors.initials: NU
authors.lastname: Uma
authors.forename: T
authors.initials: T
authors.lastname: Kokubun
authors.forename: R J
authors.initials: RJ
authors.lastname: Grayer
authors.forename: O T
authors.initials: OT
authors.lastname: Ogundipe
authors.forename: M S J
authors.initials: MS
authors.lastname: Simmonds
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001407:Bacillus / Q000187:drug effects; D032902:Ganoderma; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D044224:Pseudomonas syringae / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts