Nuances of new anti-Aspergillus antifungals.
Invasive aspergillosis (IA) is a serious complication of immunosuppression, and has become more widespread as the immunocompromised population has increased as a result of new treatment strategies and diseases. This paper identifies and discusses seven issues for managing IA and combating drug resistance. Management of IA requires a multifactorial approach with the host as a major contributor to management strategies and outcome. However, significant progress has been made, and with careful use of the clinical tools available it is possible to make a successful impact on infection outcomes.
Perfect
J R
JR
Duke University Medical Center, Durham, NC 27710, USA. perfe001@mc.duke.edu
D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology / Q000601:surgery; D001230:Aspergillus / Q000187:drug effects*; D025141:Drug Resistance, Fungal; D006801:Humans
D000935:Antifungal Agents