title: Proptosis and decreased vision secondary to prostate cancer orbital wall metastasis.
abstract: The case of a 66-year-old gentleman who presented with unilateral proptosis, eye pain and partial loss of vision seven years after his original prostate cancer diagnosis is reported. MRI of the orbits revealed a 2-cm lesion in the posterolateral right orbital wall near the optic foramen with compression of the optic nerve. Metastatic orbital lesions are relatively uncommon in prostate cancer. Treatment is palliative and varies according to the time of presentation in the course of the disease. This patient's symptoms resolved after reinitiation of combined androgen blockade.
authors.affiliation: Sinai Grace Hospital, Detroit Medical Center/Wayne State University, 6071 W. Outer Dr., Detroit, MI 48235, USA.
authors.forename: Asmita R
authors.initials: AR
authors.lastname: Patel
authors.forename: Karin B
authors.initials: KB
authors.lastname: Olson
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Pienta
mesh_terms: D000368:Aged; D000813:Anilides / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005094:Exophthalmos / Q000209:etiology*; D006801:Humans; D016729:Leuprolide / Q000008:administration & dosage; D008297:Male; D009570:Nitriles; D009918:Orbital Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary*; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D014105:Tosyl Compounds; D014786:Vision Disorders / Q000209:etiology*
chemical_list: D000813:Anilides; D009570:Nitriles; D014105:Tosyl Compounds; C053541:bicalutamide; D016729:Leuprolide