title: Fiber-optic-bundle-based optical coherence tomography.
abstract: A fiber-optic-bundle-based optical coherence tomography (OCT) probe method is presented. The experimental results demonstrate this multimode optical fiber-bundle-based OCT system can achieve a lateral resolution of 12 microm and an axial resolution of 10 microm with a superluminescent diode source. This novel OCT imaging approach eliminates any moving parts in the probe and has a primary advantage for use in extremely compact and safe OCT endoscopes for imaging internal organs and great potential to be combined with confocal endoscopic microscopy.
authors.affiliation: Beckman Laser Institute, Department of Biomedical Engineering, Pulmonary and Critical Care Division, UC Irvine Medical Center, University of California, Irvine, Irvine, California 92612, USA. txie@uci.edu
authors.forename: Tuqiang
authors.initials: T
authors.lastname: Xie
authors.forename: David
authors.initials: D
authors.lastname: Mukai
authors.forename: Shuguang
authors.initials: S
authors.lastname: Guo
authors.forename: Matthew
authors.initials: M
authors.lastname: Brenner
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000818:Animals; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D007089:Image Enhancement / Q000295:instrumentation* / Q000379:methods; D055100:Optical Fibers; D011817:Rabbits; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods; D014132:Trachea / Q000166:cytology*