Medianecrosis of the aorta (MNA)--Gsell-Erdheim syndrome: main histopathological features.
Twenty four cases of Gsell-Erdheim syndrome observed in 1999-2001 have been examined. There were 20 men (83.4%) and 4 women (16.6%). The age ranged from 22 to 69 years but 6 men (25%) died at age under 50. The following variants of aortic lesions were revealed in autopsy material: intimal tear with the following dissection which extends along the aorta to variable distances--in most cases into iliac arteries. The morphologic changes, associated with were: anuclear zones, elastolysis, thinning, dyschromia and fragmentation of elastic fibers, focal hyperelastosis. Such changes were revealed in all parts of the aortic wall, independently of the site of rupture.
Zerbino
Dmytrij
D
Institute of Clinical Pathology, Danylo Halytsky Lviv State Medical University, Lviv, Ukraine. zerbino@meduniv.lviv.ua
Kusik
Julia
J
Havrilyuk
Elena
E
D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000209:etiology* / Q000473:pathology; D001011:Aorta / Q000473:pathology*; D001014:Aortic Aneurysm / Q000209:etiology* / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000150:complications* / Q000473:pathology; D017540:Tunica Media / Q000473:pathology*