Drug-resistant diarrheogenic Escherichia coli, Mexico.
Diarrheogenic Escherichia coli isolates from 45 (73%) of 62 hospitalized patients were resistant to common antimicrobial drugs. Sixty-two percent were multidrug resistant, and >70% were resistant to trimethoprim-sulfamethoxazole and ampicillin. Ciprofloxacin and cefotaxime were uniformly active. Effective and safe oral agents are needed to treat children with bacterial diarrhea.
Estrada-García
Teresa
T
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Distrito Federal, Mexico. testrada@cinvestav.mx
Cerna
Jorge F
JF
Paheco-Gil
Leova
L
Velázquez
Raúl F
RF
Ochoa
Theresa J
TJ
Torres
Javier
J
DuPont
Herbert L
HL
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D003967:Diarrhea / Q000188:drug therapy / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008800:Mexico; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial