Hormonal therapy for acne using oral contraceptive pills.
The etiology of acne vulgaris is multifactorial and complex. The four key factors involved in the development of acne include follicular plugging, inflammation, the presence and activity of Propionibacterium acnes, and sebum. Androgen hormones stimulate the sebaceous gland and promote sebum excretion. Therefore, therapies that have an overall antiandrogen effect, like combination oral contraceptive pills, may be useful in the management of acne vulgaris. Numerous combination oral contraceptive pills have been evaluated in the treatment of acne vulgaris and have been found to be effective. With a thorough understanding of their proper use and potential associated risks, these hormonal treatments may be prescribed safely and effectively to women with acne.
Harper
Julie C
JC
Department of Dermatology, University of Alabama at Birmingham, Eye Foundation Hospital, 35294-0009, USA. jcharper@uab.edu
D000152:Acne Vulgaris / Q000188:drug therapy* / Q000503:physiopathology; D003277:Contraceptives, Oral, Combined / Q000627:therapeutic use; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016896:Treatment Outcome
D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal