Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin.
Ratliff
Timothy L
TL
D018830:Adhesins, Escherichia coli; D000818:Animals; D001422:Bacterial Adhesion / Q000502:physiology*; D004187:Disaccharides / Q000378:metabolism / Q000494:pharmacology; D004926:Escherichia coli / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology*; D036781:Fimbriae Proteins / Q000037:antagonists & inhibitors*; D005632:Fructose / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D037241:Mannose-Binding Lectins / Q000502:physiology*; D008362:Mannosides / Q000378:metabolism / Q000494:pharmacology*; D009005:Monosaccharides / Q000378:metabolism / Q000494:pharmacology; D011971:Receptors, Immunologic / Q000502:physiology*; D014552:Urinary Tract Infections / Q000382:microbiology*; D019459:Urothelium / Q000382:microbiology; D037521:Virulence Factors / Q000037:antagonists & inhibitors*
D018830:Adhesins, Escherichia coli; D004187:Disaccharides; D037241:Mannose-Binding Lectins; D008362:Mannosides; D009005:Monosaccharides; D011971:Receptors, Immunologic; D037521:Virulence Factors; C058769:fimH protein, E coli; C037872:pili, bacterial receptor; D036781:Fimbriae Proteins; D005632:Fructose