[1-amino-2-butanols derivates with antiarrhythmic effect].
R(-), R, S, S(+)-1-N-theophylline-7-acetyl or ethyl/-amino-2-butanols were obtained in the reaction of 7-methoxycarbonylmethyltheophylline or 7-beta-chloroethyltheophylline with R(-), R, S, S(+) 1-amino-2-butanols. Compounds I and II tested for antiarrhythmic and hypotensive activity were inactive.
Gajewczyk
L
L
Zakład Technologii Chemicznej Srodków Leczniczych, Akademia Medyczna, ul. Skałeczna 10, 31-065 Kraków.
Zejc
A
A
D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000959:Antihypertensive Agents / Q000737:chemistry / Q000494:pharmacology; D000440:Butanols / Q000138:chemical synthesis* / Q000494:pharmacology*; D002626:Chemistry, Pharmaceutical
D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D000440:Butanols