title: Transcriptional regulation at the chromatin level in the cardiovasculature through protein-protein interactions and chemical modifications.
abstract: Transcriptional regulation in eukaryotes requires an understanding of the regulation of the chromatin structure. Chromatin is the eukaryotic-specific packaging/compaction of DNA with nucleosomal histones. This present review discusses recent advancements made in the field of chromatin-associated transcriptional regulation and their implications to the cardiovasculature.
authors.affiliation: Department of Cardiovascular Medicine, Graduate School of medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. torusuzu-tky@umin.ac.jp
authors.forename: Toru
authors.initials: T
authors.lastname: Suzuki
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Matsumura
authors.forename: Ryozo
authors.initials: R
authors.lastname: Nagai
mesh_terms: D002320:Cardiovascular Physiological Phenomena; D002843:Chromatin / Q000502:physiology*; D006801:Humans; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*; D014158:Transcription, Genetic / Q000502:physiology*
chemical_list: D002843:Chromatin; D011506:Proteins