Oral Candida isolates colonizing or infecting human immunodeficiency virus-infected and healthy persons in Mexico.
Oral yeast carriage was studied in 312 Mexican subjects. Candida albicans was the most frequent species, but other Candida spp. were isolated from 16.5 to 38.5% of patients. Colonization did not correlate with CD4+ number or viral load, but highly active antiretroviral therapy reduced the frequency of candidiasis. Most isolates were susceptible to fluconazole, but 10.8% were resistant to one or more azoles.
Sánchez-Vargas
Luis Octavio
LO
Laboratorio de Micología Médica, Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain.
Ortiz-López
Natalia Guadalupe
NG
Villar
María
M
Moragues
María Dolores
MD
Aguirre
José Manuel
JM
Cashat-Cruz
Miguel
M
Lopez-Ribot
Jose Luis
JL
Gaitán-Cepeda
Luis Alberto
LA
Quindós
Guillermo
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D023241:Antiretroviral Therapy, Highly Active; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification*; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology; D015658:HIV Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*
D015725:Fluconazole