Characterization of interferon a2B pegylated via carboxyalkylation: a case study.
Wylie
David C
DC
Biotechnology Development, Schering Plough Research Institute, Union, NJ, USA.
Voloch
Marcio
M
Lee
Seoju
S
Liu
Yan-Hui
YH
Cutler
Collette
C
Larkin
Brittany
B
Cannon-Carlson
Susan
S
D000478:Alkylation; D002264:Carboxylic Acids / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D007536:Isomerism; D010446:Peptide Fragments / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D010449:Peptide Mapping; D011092:Polyethylene Glycols / Q000737:chemistry*; D011994:Recombinant Proteins; D017421:Sequence Analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D002264:Carboxylic Acids; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D010446:Peptide Fragments; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; C417083:peginterferon alfa-2b