G 6 PD deficiency induced hemolysis in diabetic twins.
We report hemolysis due to glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in two Egyptian monozygotic brothers, at the onset of diabetes type 1. Hemolysis occurred following the treatment of hyperglycemia and ketoacidosis (one twin). It was related to unknown G-6-PD deficiency. The fall in glucose availability after the treatment of hyper glycemia is proposed as a possible etiology for hemolysis.
Haroun
Medhat
M
Department of Biotechnology, IGSR,Alexandria University, Alexandria, Egypt. mharounag@yahoo.com
D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy; D004200:Diseases in Twins; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D014430:Twins, Monozygotic
D007004:Hypoglycemic Agents; D007328:Insulin