title: Bacterial chromatin.
abstract: Recent studies have revealed that the bacterial nucleoid is a dynamic entity that alters its overall structure in response to changes in both growth rate and growth phase. These structural changes are correlated with, and might be driven by, changes in the distribution and utilization of DNA supercoiling. In turn, these parameters in addition to the delimitation of topological domains are dependent both on the relative proportions of the abundant nucleoid-associated proteins and on transcriptional activity. The domain structure itself is dynamic.
authors.affiliation: MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK. aat@mrc-lmb.cam.ac.uk
authors.forename: Andrew
authors.initials: A
authors.lastname: Travers
authors.forename: Georgi
authors.initials: G
authors.lastname: Muskhelishvili
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D002843:Chromatin / Q000378:metabolism*; D002876:Chromosomes, Bacterial; D015870:Gene Expression
chemical_list: D001426:Bacterial Proteins; D002843:Chromatin