title: Photodynamic therapy in the treatment of rosacea.
abstract: BACKGROUND
  Rosacea is a common disease, with an estimated prevalence of 5-10%. Established systemic and topical treatment is often effective but requires continuous medication.
  
  
  OBJECTIVE
  We report the outcome of photodynamic therapy (PDT) in 4 patients with rosacea.
  
  
  METHODS
  Prior treatment consisted of standard treatment with tetracycline and metronidazole. The treatment was however either ineffective or the patients were dissatisfied with the need for continuous treatment. The patients all received standard treatment with PDT.
  
  
  RESULTS
  The treated skin cleared in 3 of the 4 patients. Treatment with light alone did not appear to have any effect. In one of the patients there has been no relapse during a 9-month follow-up. In 2 patients, remissions lasted 3 months, during which time no additional or supplementary treatment was used.
  
  
  CONCLUSIONS
  Our observation suggests that PDT may play a role in the future treatment of selected cases of rosacea.
authors.affiliation: Division of Dermatology, Department of Medicine, Roskilde Hospital, Roskilde, Denmark.
authors.forename: Hanne
authors.initials: H
authors.lastname: Nybaek
authors.forename: Gregor B E
authors.initials: GB
authors.lastname: Jemec
mesh_terms: D000328:Adult; D000368:Aged; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use; D012008:Recurrence; D018570:Risk Assessment; D012393:Rosacea / Q000175:diagnosis* / Q000188:drug therapy*; D012494:Sampling Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D017319:Photosensitizing Agents