title: Seroprevalence and incidence of rubella in and around Delhi (1988-2002).
abstract: National Institute of Communicable Diseases (NICD) has been engaged in rubella testing for serodiagnosis of the infection and screening for immunity status. The compiled and evaluated data of the work done on rubella testing for the past fifteen years has been presented here to show the trend and changing scenario of the disease in Delhi. Blood samples were from 7424 patients referred to NICD, Delhi for serodiagnosis of congenital Rubella syndrome (CRS) in malformed babies, in utero rubella infection in women and immunity status of pregnant women and women with bad obstetric history. They were tested for rubella IgG and/or rubella IgM antibodies using commercially available reagents and kits. The data from the 15 years of testing was then compiled and evaluated. From the available data it was seen that immunity status against rubella in childbearing age group of women increased steadily from 49% in 1988 to 87% in 2002. Reported cases of CRS at NICD are also on the decline over the time period. There is periodic indication of high incidence of rubella in the year 1988; 1991 and 1998 as the reported cases of acute rubella infection in childbearing age group is high during these years.
authors.affiliation: Microbiology Division, National Institute of Communicable Diseases, New Delhi - 110 054, India.
authors.forename: I
authors.initials: I
authors.lastname: Gandhoke
authors.forename: R
authors.initials: R
authors.lastname: Aggarwal
authors.forename: S
authors.initials: S
authors.lastname: Lal
authors.forename: S
authors.initials: S
authors.lastname: Khare
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007194:India / Q000453:epidemiology; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000821:virology*; D012189:Retrospective Studies; D012409:Rubella / Q000453:epidemiology* / Q000821:virology; D012412:Rubella virus / Q000302:isolation & purification*; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; C040901:rubella antibodies