title: Mass, EPR, IR and electronic spectroscopic studies on newly synthesized macrocyclic ligand and its transition metal complexes.
abstract: Manganese(II), cobalt(II), nickel(II) and copper(II) complexes have been synthesized with a new tetradentate ligand viz. 1,3,7,9-tetraaza-2,4,8,10-tetraketo-6,12-diphenyl-cyclododecane (L) and characterized by the elemental analysis, molar conductance measurements, magnetic susceptibility measurements, mass, 1H NMR, IR, electronic and EPR spectral studies. The molar conductance measurements of the complexes in DMF correspond to be nonelectrolytic nature for Mn(II), Co(II) and Cu(II) while 1:2 electrolytes for Ni(II) complexes. Thus, these complexes may be formulated as [M(L)X2] and [Ni(L)]X2 (where M=Mn(II), Co(II) and Cu(II) and X=Cl- and NO3-). On the basis of IR, electronic and EPR spectral studies an octahedral geometry has been assigned for Mn(II) and Co(II) complexes, square-planar for Ni(II) whereas tetragonal for Cu(II) complexes. The ligand and its complexes were also evaluated against the growth of bacteria and pathogenic fungi in vitro.
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, JLN-Marg, New Delhi 110002, India. schandra_00@yahoo.com
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.forename: Lokesh Kumar
authors.initials: LK
authors.lastname: Gupta
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D008024:Ligands; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D008280:Magnetics; D008345:Manganese / Q000737:chemistry; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D028561:Transition Elements / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D008024:Ligands; D047028:Macrocyclic Compounds; D028561:Transition Elements; D003035:Cobalt; D008345:Manganese; D003300:Copper; D009532:Nickel