title: Diagnosis of central venous catheter related infection in adult patients.
abstract: Intravascular catheters are one of the main causes of bacteraemia and septicaemia in hospitalised patients and continue to be associated with a significant morbidity and mortality. Two main types of infections occur, they can be either localised at the catheter insertion site of systemic with a septicaemia. The clinical parameters related to these infections are presented. The laboratory diagnosis of these infections is also extensively reviewed and recommendations are made as to the most appropriate diagnostic method to be used.
authors.affiliation: Department of Pharmaceutical and Biological Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
authors.forename: Tony
authors.initials: T
authors.lastname: Worthington
authors.forename: Tom S J
authors.initials: TS
authors.lastname: Elliott
mesh_terms: D000165:Acridine Orange; D000465:Algorithms; D000907:Antibodies, Bacterial / Q000097:blood; D016470:Bacteremia / Q000382:microbiology; D001424:Bacterial Infections / Q000097:blood / Q000175:diagnosis*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000145:classification / Q000295:instrumentation; D002408:Catheters, Indwelling / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005456:Fluorescent Dyes; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood
chemical_list: D000907:Antibodies, Bacterial; D005456:Fluorescent Dyes; D007074:Immunoglobulin G; D000165:Acridine Orange