title: The use of an insuflon device for the administration of G-CSF in pediatric cancer patients.
abstract: In pediatric oncology, granulocyte colony-stimulating factor (G-CSF) is applied with the aim of shortening neutropenic periods after chemotherapy and for mobilization of peripheral blood stem cells for apheresis procedures. G-CSF is administered, subcutaneously or intravenously, on a daily basis. An insuflon device for the administration of G-CSF was used in 29 patients for 93 G-CSF periods. Retrospective evaluation shows that this administration route is feasible, safe and preferred by young children rather than by teenagers with cancer.
authors.affiliation: Department of Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: M E A
authors.initials: ME
authors.lastname: de Jong
authors.forename: T
authors.initials: T
authors.lastname: Carbière
authors.forename: M M
authors.initials: MM
authors.lastname: van den Heuvel-Eibrink
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000139:chemically induced / Q000517:prevention & control*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004867:Equipment Design; D004869:Equipment Safety; D005240:Feasibility Studies; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007275:Injections, Intravenous / Q000295:instrumentation; D007279:Injections, Subcutaneous / Q000295:instrumentation; D009369:Neoplasms / Q000188:drug therapy*; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D016179:Granulocyte Colony-Stimulating Factor