title: Ubiquitin at Fox Chase.
abstract: My interest in protein breakdown as a research problem began in 1955. In 1963, when we relocated from Yale to the Institute for Cancer Research of Fox Chase, Philadelphia, nothing new was being reported. Here, I review how we get the ubiquitin proteasome system all together.
authors.affiliation: Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA. irose@uci.edu
authors.forename: I
authors.initials: I
authors.lastname: Rose
mesh_terms: D000818:Animals; D001671:Biochemistry / Q000266:history*; D049673:History, 20th Century; D006801:Humans; D008954:Models, Biological; D008956:Models, Chemical; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D025801:Ubiquitin / Q000378:metabolism*; D014481:United States
chemical_list: D025801:Ubiquitin; D046988:Proteasome Endopeptidase Complex