title: Performance of a rapid immunochromatographic screening test for detection of antibodies to human immunodeficiency virus type 1 (HIV-1) and HIV-2: experience at a tertiary care hospital in South India.
abstract: The performance characteristics of a rapid immunochromatographic-screening test, SD Bioline HIV-1/2 3.0 (Standard Diagnostics Inc., Kyonggi-do, South Korea) on 23,754 sera and 30 plasma samples are reported. The sensitivity and specificity for the assay on serum samples are 100% and 99.4%, respectively. The assay detected antibodies in individuals infected with human immunodeficiency virus type 1 (HIV-1) genotypes A and C and HIV-2. This straightforward assay is a reliable diagnostic tool for screening HIV in resource-poor settings.
authors.affiliation: Department of Clinical Virology, Christian Medical College, Vellore, Tamil Nadu PIN 632004, India.
authors.forename: Theophilus-Sunder
authors.initials: TS
authors.lastname: Vijayakumar
authors.forename: Shoba
authors.initials: S
authors.lastname: David
authors.forename: Kavitha
authors.initials: K
authors.lastname: Selvaraj
authors.forename: Thiruppavai
authors.initials: T
authors.lastname: Viswanathan
authors.forename: Rajesh
authors.initials: R
authors.lastname: Kannangai
authors.forename: Gopalan
authors.initials: G
authors.lastname: Sridharan
mesh_terms: D002845:Chromatography / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D015483:HIV Antibodies / Q000097:blood*; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D011933:Reagent Kits, Diagnostic
chemical_list: D015483:HIV Antibodies; D011933:Reagent Kits, Diagnostic