Micro-synthesis and electron ionization mass spectral analysis of O-alkyl N,N-dialkylphosphoramidocyanidates.
This communication describes microsynthesis and GC/MS analysis of O-alkyl N,N-dialkylphosphoramidocyanidates (ADAPCs), which are analogues of chemical warfare agent, Tabun. The study was undertaken with a view to develop spectral data base of ADAPCs for verification purpose of Chemical Weapons Convention (CWC). Reported microsynthetic approach has advantages over traditional synthesis in terms of efficiency, synthetic waste, and exposure to toxic chemicals. GC/MS analysis of variety of these compounds (ADAPCs) was performed. Based on the obtained mass spectra of structurally diverse ADAPCs, the fragmentation routes are proposed, which explains most of the characteristic ions.
Gupta
Arvind K
AK
Vertox Laboratory, Defence Research and Development Establishment, Gwalior, India.
Palit
Meehir
M
Pardasani
Deepak
D
Shakya
Purushottam
P
Srivastava
Rejendra K
RK
Dubey
Devendra K
DK
D002618:Chemical Warfare; D002619:Chemical Warfare Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D002800:Cholinesterase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D010755:Organophosphates / Q000737:chemistry*; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization
D002619:Chemical Warfare Agents; D002800:Cholinesterase Inhibitors; D010755:Organophosphates; C009374:tabun