title: Adhesion of polymer vesicles.
abstract: The adhesion and bending modulus of polybutadiene-poly(ethylene oxide) block copolymer vesicles made from a bidisperse mixture of polymers is measured using micropipette aspiration. The adhesion energy between biotinylated vesicles and avidin beads is modeled by incorporating the extension of the adhesive ligands above the surface brush of the vesicle according to the blob model of bidisperse polymer mixtures of Komura and Safran assuming the polymer brush at the surface of the vesicle is compact. The same model accurately reproduces the scaling of the bending modulus with polymer composition.
authors.affiliation: Department of Chemical and Biomolecular Engineering and the Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: John J
authors.initials: JJ
authors.lastname: Lin
authors.forename: Frank S
authors.initials: FS
authors.lastname: Bates
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Hammer
authors.forename: James A
authors.initials: JA
authors.lastname: Silas
mesh_terms: D001360:Avidin / Q000737:chemistry*; D001710:Biotin / Q000737:chemistry*; D002070:Butadienes / Q000737:chemistry*; D020724:Elastomers; D008956:Models, Chemical; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties; D000267:Tissue Adhesions
chemical_list: D002070:Butadienes; D020724:Elastomers; D011108:Polymers; D001360:Avidin; D011092:Polyethylene Glycols; D001710:Biotin; C028834:polybutadiene