Factors influencing early virological response in children with chronic hepatitis C treated with pegylated interferon and ribavirin.
Combined therapy with pegylated IFN-alpha and ribavirin enables to achieve EVR in 8/10 treated children with CHC infected with genotype 1. Lower ALT activity, lower HCV viral load and small progression of fibrosis in the histopathological evaluation have positive influence on EVR.
Kowala-Piaskowska
Arleta
A
Department of Infectious Diseases and Child Neurology, Karol Marcinkowski University of Medical Sciences, Szpitalna 27/33, 60-572 Poznan, Poland.
Słuzewski
Wojciech
W
Figlerowicz
Magdalena
M
Mozer-Lisewska
Iwona
I