Social circuits: peptidergic regulation of mammalian social behavior.
Mammals have developed patterns of social relationships that enhance the survival of individuals and maximize the reproductive success of species. Although social stimuli and social responses are highly complex, recent studies are providing substantial insights into their neural substrates. Neural pathways employing the nonapeptides vasopressin and oxytocin play a particularly prominent role both in social recognition and the expression of appropriate social responses. New insights into social neuroscience are discussed, along with the relevance of this rapidly developing field to human relationships and disease processes.
Storm
Elaine E
EE
Department of Psychiatry, Center for Neurobiology and Psychiatry, Insitute for Neurodegenerative Diseases, University of California, San Francisco School of Medicine, San Francisco, CA 94143, USA.
Tecott
Laurence H
LH
D000818:Animals; D001921:Brain / Q000502:physiology*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D009479:Neuropeptides / Q000378:metabolism*; D010121:Oxytocin / Q000378:metabolism; D012919:Social Behavior; D014667:Vasopressins / Q000378:metabolism
D009479:Neuropeptides; D014667:Vasopressins; D010121:Oxytocin