[Paraneoplastic nephrotic syndrome associated with broncho-pulmonary cancer].
BACKGROUND
Paraneoplastic nephrotic syndrome associated with malignant broncho-pulmonary tumors. Three cases and literature review. Malignant broncho-pulmonary tumours are the principal cause of a paraneoplastic nephrotic syndrome. These tumours are most often small cell or squamous bronchial carcinomas. In 75% of cases the nephrotic syndrome is due to a membranous glomerulonephritis and it usually precedes the discovery of the causative tumour.


METHODS
Three cases of paraneoploastic nephrotic syndrome associated with bronchial carcinoma are described. The first is of a bronchial carcinoid tumour associated with a membrano-proliferative glomerulonephritis. In the second a bronchial adenocarcinoma was revealed by a membranous glomerulonephritis. The last case concerns a squamous carcinoma associated with a nephrotic syndrome in which the histological lesions were not documented on account of progression to rapidly fatal acute renal failure.


CONCLUSIONS
A revue of the literature describes the associations between paraneoplastic nephrotic syndrome and bronchial carcinoma.
Menivale
F
F
Service de Pneumologie, Hôpital Maison Blanche, CHU de Reims, France.
Deslée
G
G
Garcia
V
V
Sartelet
H
H
Wynckel
A
A
Lebargy
F
F
D000328:Adult; D000368:Aged; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000209:etiology*