title: Efficient copper-catalyzed N-arylation of sulfoximines with aryl iodides and aryl bromides.
abstract: Two simple and inexpensive systems for copper-catalyzed N-arylations of sulfoximines with aryl bromides and aryl iodides have been developed. Using 10 mol % of a copper(I) salt in combination with 20 mol % of a 1,2-diamine and Cs2CO3 provides N-arylated sulfoximines in high yields. Various functional groups and heteroatoms are tolerated. The method is complementary to the known protocols for N-arylations of sulfoximines, which require stoichiometric quantities of copper salts or cost-intensive palladium/BINAP catalysts.
authors.affiliation: Institute of Organic Chemistry, RWTH-Aachen University, Landoltweg 1, D-52056 Aachen, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Sedelmeier
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm