title: [Protective effect of purariae isoflavone on apoptosis cells of nasal mocosas in ovariectomized rats].
abstract: OBJECTIVE
  To study the protective effect of purariae isoflavone on apoptosis cells of atrophic nasal mucosas in ovariectomized rats.
  
  
  METHODS
  60 rats were divided into four groups as control, ovariectomized, ovariectomized + nylestriol (O + N) and ovariectomized + purariae isoflavone (O + P), each with 15 rats. Earlier apotosis cells of mucosas taken from nasal septum were measured with flow cytometry.
  
  
  RESULTS
  Compared with control group, and the number of apoptosis cells of mucosas increased after being ovariectomized,and the number of apoptosis cells of mucosas in O + N and O + D group didn't change.
  
  
  CONCLUSIONS
  Nylestriol and purariae isoflavone might have effects on protecting cells of mucosas from lacking of estrogen by decreasing apoptosis cells in ovariectomized rats.
authors.affiliation: The First People's Hospital of Yunnan Province, Kunming 650001, China. qibenming@21cn.com
authors.forename: Ben-Ming
authors.initials: BM
authors.lastname: Qi
authors.forename: Chun-Chun
authors.initials: CC
authors.lastname: Cai
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Deng
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D004847:Epithelial Cells / Q000473:pathology*; D045166:Estradiol Congeners / Q000494:pharmacology; D005260:Female; D007529:Isoflavones / Q000302:isolation & purification / Q000494:pharmacology*; D009297:Nasal Mucosa / Q000473:pathology*; D010052:Ovariectomy; D010946:Plants, Medicinal / Q000737:chemistry; D020011:Protective Agents / Q000302:isolation & purification / Q000494:pharmacology; D029908:Pueraria / Q000737:chemistry; D011800:Quinestrol / Q000031:analogs & derivatives / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D045166:Estradiol Congeners; D007529:Isoflavones; D020011:Protective Agents; C010722:nylestriol; D011800:Quinestrol