Evolutionary history of the greater white-toothed shrew (Crocidura russula) inferred from analysis of mtDNA, Y, and X chromosome markers.
We investigate the evolutionary history of the greater white-toothed shrew across its distribution in northern Africa and mainland Europe using sex-specific (mtDNA and Y chromosome) and biparental (X chromosome) markers. All three loci confirm a large divergence between eastern (Tunisia and Sardinia) and western (Morocco and mainland Europe) lineages, and application of a molecular clock to mtDNA divergence estimates indicates a more ancient separation (2.25 M yr ago) than described by some previous studies, supporting claims for taxonomic revision. Moroccan ancestry for the mainland European population is inconclusive from phylogenetic trees, but is supported by greater nucleotide diversity and a more ancient population expansion in Morocco than in Europe. Signatures of rapid population expansion in mtDNA, combined with low X and Y chromosome diversity, suggest a single colonization of mainland Europe by a small number of Moroccan shrews >38 K yr ago. This study illustrates that multilocus genetic analyses can facilitate the interpretation of species' evolutionary history but that phylogeographic inference using X and Y chromosomes is restricted by low levels of observed polymorphism.
Brändli
Laura
L
Department of Ecology and Evolution, University of Lausanne, Biology Building, CH-1015 Lausanne, Switzerland. Laura.Braendli@unil.ch
Handley
Lori-Jayne Lawson
LJ
Vogel
Peter
P
Perrin
Nicolas
N
D000352:Africa, Northern; D000818:Animals; D001483:Base Sequence; D001499:Bayes Theorem; D016000:Cluster Analysis; D017931:DNA Primers; D004272:DNA, Mitochondrial / Q000235:genetics; D003710:Demography; D005060:Europe; D019143:Evolution, Molecular; D014644:Genetic Variation; D005843:Geography; D008957:Models, Genetic; D008969:Molecular Sequence Data; D010802:Phylogeny; D011157:Population Dynamics; D017422:Sequence Analysis, DNA; D012788:Shrews / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics; D014998:Y Chromosome / Q000235:genetics
D017931:DNA Primers; D004272:DNA, Mitochondrial