title: Relation of anemia at discharge to survival after acute coronary syndromes.
abstract: Two-year survival rate was assessed among 1,038 patients who had acute coronary syndromes that were classified by discharge hematocrit values as normal (>39%, n = 360, 34.7%), mildly anemic (33.1% to 39%, n = 430, 41.4%), or moderately/severely anemic (< or = 33%, n = 248, 23.9%). Worsening anemia was associated with a decreased 2-year survival rate (normal 95.8%, mild anemia 91.2%, moderate/severe anemia 81.5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia.
authors.affiliation: Mid America Heart Institute of Saint Luke's Hospital, Missouri, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Vaglio
authors.forename: David M
authors.initials: DM
authors.lastname: Safley
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rahman
authors.forename: Mikhail
authors.initials: M
authors.lastname: Kosiborod
authors.forename: Philip
authors.initials: P
authors.lastname: Jones
authors.forename: Randall
authors.initials: R
authors.lastname: Thompson
authors.forename: Harlan M
authors.initials: HM
authors.lastname: Krumholz
authors.forename: John A
authors.initials: JA
authors.lastname: Spertus
mesh_terms: D000368:Aged; D000740:Anemia / Q000503:physiopathology*; D000789:Angina, Unstable / Q000097:blood / Q000401:mortality* / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D002423:Cause of Death / Q000639:trends; D017023:Coronary Angiography; D018450:Disease Progression; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006400:Hematocrit / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D009203:Myocardial Infarction / Q000097:blood / Q000401:mortality* / Q000503:physiopathology; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors; D014336:Troponin / Q000097:blood
chemical_list: D015415:Biomarkers; D014336:Troponin