title: Successful lung transplantation from a donor with a saddle pulmonary embolus.
abstract: Pulmonary embolus has received scant attention as a contraindication to lung donation. Reported is a case of a saddle pulmonary embolus successfully treated with thrombolytics in a donor whose lung was ultimately successfully transplanted. Discussed are the theoretical likelihood of thromboembolus in potential lung donors and the possible implications of pulmonary embolism on donor selection and lung physiology around the time of transplantation.
authors.affiliation: Walter Reed Army Medical Center, Washington, DC 20307, USA. dsfrenia@comcast.net
authors.forename: Douglas
authors.initials: D
authors.lastname: Frenia
authors.forename: Steven D
authors.initials: SD
authors.lastname: Nathan
authors.forename: Shahzad
authors.initials: S
authors.lastname: Ahmad
authors.forename: Melanie
authors.initials: M
authors.lastname: Guerrero
authors.forename: David
authors.initials: D
authors.lastname: Distefano
authors.forename: Paul
authors.initials: P
authors.lastname: Massamiano
authors.forename: Edward
authors.initials: E
authors.lastname: Lefrak
authors.forename: Nelson
authors.initials: N
authors.lastname: Burton
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D020521:Stroke / Q000175:diagnosis* / Q000628:therapy; D015912:Thrombolytic Therapy / Q000379:methods; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome