title: HLA genes in Mexican Teeneks: HLA genetic relationship with other worldwide populations.
abstract: The HLA allele frequency distribution of the Mexican Teenek Indians has been studied and compared with those of other First American Natives and worldwide populations (a total of 15694 chromosomes from 73 different populations were analyzed). This study corroborate the restricted HLA polymorphism in the Amerindian populations and demonstrate how the Amerindians show a relatively homogeneity as opposed to other First Native American groups. Finally, the present data support previous ones that state the lack of complete correlation between language and genetics in micro-environmental studies; Teenek Mayan language does not correspond with a close Mayan (Guatemala) relatedness.
authors.affiliation: Department of Physiology and Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiología Ignacio Chávez, 14080 Mexico City, Mexico. gvargas63@yahoo.com
authors.forename: Gilberto
authors.initials: G
authors.lastname: Vargas-Alarcón
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Hernández-Pacheco
authors.forename: Juan
authors.initials: J
authors.lastname: Moscoso
authors.forename: Nonanzit
authors.initials: N
authors.lastname: Pérez-Hernández
authors.forename: Luis Enrique
authors.initials: LE
authors.lastname: Murguía
authors.forename: Almudena
authors.initials: A
authors.lastname: Moreno
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: Serrano-Vela
authors.forename: Julio
authors.initials: J
authors.lastname: Granados
authors.forename: Antonio
authors.initials: A
authors.lastname: Arnaiz-Villena
mesh_terms: D000483:Alleles; D002877:Chromosomes, Human / Q000235:genetics*; D005787:Gene Frequency; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D007199:Indians, South American / Q000145:classification / Q000235:genetics*; D010802:Phylogeny; D011153:Population / Q000235:genetics*
chemical_list: D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II