[Synthesis of 1-N-aryloacetamidobutanol derivatives with anti-seizure effect].
New derivatives of 1-N-aryloacetamidobutanols were obtained in the reaction of arylalkylcarboxylic acid chlorides with R, S, R(-), S(+) 1-amino-2-butanols. Structures of the obtained compounds have been confirmed by elemental analysis and IR-spectrometry. Results of pharmacological studies will be published elsewhere.
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Zakład Technologii Chemicznej Srodków Leczniczych, Akademia Medyczna, ul. Skałeczna 10, 31-065 Kraków.
Zejc
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D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology*; D000440:Butanols / Q000138:chemical synthesis* / Q000494:pharmacology*; D002626:Chemistry, Pharmaceutical; D012640:Seizures / Q000188:drug therapy; D013050:Spectrometry, Fluorescence
D000927:Anticonvulsants; D000440:Butanols