Controlling sialorrhoea: a review of available treatment options.
Sialorrhoea (drooling or excessive salivation) is a common symptom of many neurological diseases (e.g., amyotropic lateral sclerosis, cerebral palsy and Parkinson's disease) and otolaryngologic diseases (tumours of upper aerodigestive tract). It is mostly caused by poor oral and facial muscle control in patients with swallowing dysfunction (secondary sialorrhoea). However, some cases of sialorrhoea are due to hypersecretion of saliva. These cases represent so-called primary sialorrhoea.
Potulska
Anna
A
Medical University, Warsaw, Department of Neurology, Poland.
Friedman
Andrzej
A
D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D015259:Dopamine Agents / Q000627:therapeutic use*; D006024:Glycopyrrolate / Q000627:therapeutic use; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D012472:Salivation / Q000187:drug effects; D012798:Sialorrhea / Q000188:drug therapy* / Q000209:etiology / Q000532:radiotherapy / Q000601:surgery
D018680:Cholinergic Antagonists; D015259:Dopamine Agents; D007980:Levodopa; D019274:Botulinum Toxins, Type A; D006024:Glycopyrrolate