Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination.
Atypical lymphoid infiltrations arose within the influenza inoculation sites of two adult female patients. One patient developed a low-grade cutaneous marginal zone B-cell lymphoma (MZL) that was responsive to local excision and radiation therapy despite spread to a distant cutaneous site. The second patient's clinical course was characterized by a locally aggressive, histologically reactive inflammatory reaction responsive only to radiation therapy after multiple failed attempts at surgical resection.
May
Steve A
SA
Department of Pathology, Baylor University Medical Center, Dallas, Texas, USA.
Netto
George
G
Domiati-Saad
Rana
R
Kasper
Candace
C
D000368:Aged; D049109:Cell Proliferation; D005260:Female; D006801:Humans; D007252:Influenza Vaccines; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D014611:Vaccination / Q000009:adverse effects*
D007252:Influenza Vaccines