Patient sex and success of peripheral percutaneous transluminal arterial angioplasty.
OBJECTIVE
Female sex negatively affects the durability of percutaneous angioplasty of native arteries supplying the lower extremity.


METHODS
Outcome analysis of the results of percutaneous angioplasty of lower extremity arteries in a single vascular surgery practice.


METHODS
University-affiliated community hospital.


METHODS
All patients undergoing percutaneous intervention on lower extremity arteries during 10 years.


METHODS
Indication for intervention, anatomic site of intervention, placement of percutaneous stents, and length of lesion undergoing angioplasty were noted. Patient demographics and risk factors were identified.


METHODS
Results were analyzed by sex. Kaplan-Meier life tables were plotted and differences between groups tested by the log-rank method. A Cox proportional hazards regression model was used to perform the multivariate analysis.


RESULTS
During 10 years, 351 angioplasties were performed in 248 patients, 173 in women and 178 in men. There was no difference between men and women in indication for intervention, length and type of lesion treated, or quality of distal runoff. Univariate survival analysis identified a difference in duration of patency between men and women (P = .047). However, multivariate analysis demonstrated no significant difference in duration of patency between men and women (P = .18). Iliac angioplasty and adequate distal runoff were positive predictors of long-term patency (P<.001 for both).


CONCLUSIONS
There appears to be no significant difference in the durability of angioplasty between men and women. However, location of angioplasty and adequacy of distal runoff may be useful in determining when to use angioplasty.
Abando
Alan
A
Division of Vascular Surgery, Department of Surgery, Keck School of Medicine of University of Southern California, Huntington Hospital, 100 West California Boulevard, Pasadena, CA 91105, USA.
Akopian
Gabriel
G
Katz
Steven G
SG
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000800:Angioplasty, Balloon / Q000379:methods*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D002140:California; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D011336:Probability; D016016:Proportional Hazards Models; D011788:Quality of Life; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D018709:Statistics, Nonparametric; D016896:Treatment Outcome