title: Medianecrosis of the aorta (MNA)--Gsell-Erdheim syndrome: main histopathological features.
abstract: Twenty four cases of Gsell-Erdheim syndrome observed in 1999-2001 have been examined. There were 20 men (83.4%) and 4 women (16.6%). The age ranged from 22 to 69 years but 6 men (25%) died at age under 50. The following variants of aortic lesions were revealed in autopsy material: intimal tear with the following dissection which extends along the aorta to variable distances--in most cases into iliac arteries. The morphologic changes, associated with were: anuclear zones, elastolysis, thinning, dyschromia and fragmentation of elastic fibers, focal hyperelastosis. Such changes were revealed in all parts of the aortic wall, independently of the site of rupture.
authors.affiliation: Institute of Clinical Pathology, Danylo Halytsky Lviv State Medical University, Lviv, Ukraine. zerbino@meduniv.lviv.ua
authors.forename: Dmytrij
authors.initials: D
authors.lastname: Zerbino
authors.forename: Julia
authors.initials: J
authors.lastname: Kusik
authors.forename: Elena
authors.initials: E
authors.lastname: Havrilyuk
mesh_terms: D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000209:etiology* / Q000473:pathology; D001011:Aorta / Q000473:pathology*; D001014:Aortic Aneurysm / Q000209:etiology* / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000150:complications* / Q000473:pathology; D017540:Tunica Media / Q000473:pathology*