title: Efficient stereochemical controllers in biaryl Suzuki coupling reactions: benzylic carbinols bearing in beta-position thioether, dimethylamino, or sulfoxide groups.
abstract: Highly atropo-diastereoselective Suzuki coupling between aryl halides bearing stereogenic benzylic carbinols with sulfoxide, thioether, or dimethylamino groups as efficient internal chelating ligands and 2-methoxy-1-naphthylboronic acid were performed with high yields; a palladacycle is proposed as a potential transition state. [reaction: see text]
authors.affiliation: Laboratoire de stéréochimie associé au CNRS, UMR 7509 Université Louis Pasteur, ECPM, 25 rue Becquerel, 67087 Strasbourg Cedex 2, France.
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Broutin
authors.forename: Françoise
authors.initials: F
authors.lastname: Colobert