title: Type 2 diabetes in children and youth.
abstract: The number of children and youth diagnosed with type 2 diabetes has increased dramatically over the last decade. Much still needs to be learned about why this epidemic is occurring presently with regard to other environmental factors that might promote insulin resistance and beta-cell failure. The TODAY trial will help to determine the best treatment strategies to improve glycemia, reduce complications, and ameliorate insulin resistance and beta-cell failure. As type 2 diabetes emerges as a worldwide public health problem, improved care for affected youth must be coupled with a focus on prevention.
authors.affiliation: Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. fkaufman@chla.usc.edu
authors.forename: Francine Ratner
authors.initials: FR
authors.lastname: Kaufman
mesh_terms: D000293:Adolescent; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000453:epidemiology; D011236:Prediabetic State / Q000453:epidemiology; D015995:Prevalence