Reversible posterior leukoencephalopathy associated with postpartum HELLP syndrome.
We describe a case of a severe, immediate postpartum HELLP syndrome (hemolysis, elevated liver enzyme levels, low platelet count) with reversible posterior leukoencephalopathy (RPLS) characterized by generalized seizure, altered mental status, and visual loss in a 37-year-old primigravid woman. Magnetic resonance brain imaging showed diffuse subcortical edema, which resolved completely after 2 weeks along with complete symptom regression. The pathogenesis of RPLS is discussed and the importance of a prompt diagnosis is emphasized, as is the crucial role of rapid blood pressure reduction.
Negro
Aurelio
A
Second Division of Internal Medicine and Hypertension Unit, Arcispedale S. Maria Nuova, Reggio Emilia, Italy. negro.aurelio@asmn.re.it
Zuccoli
Giulio
G
Regolisti
Giuseppe
G
Mastrangeli
Sandro
S
Rossi
Ermanno
E