[Familial small-vessel vasculitis of the kidney].
BACKGROUND
Familial forms of small-vessel vasculitis has been reported in 14 families (including this one).


METHODS
A father and son were both diagnosed with renal vasculitis (pauci-immune crescentic glomerulonephritis). Both had antimyeloperoxidase autoantibodies, and there was no evidence of a common environmental factor.


CONCLUSIONS
These cases suggest the role of constitutional factors in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.
Devaux
J P
JP
Service de Medecine Internenéphrologie, Centre Hospitalier de Valenciennes.
Kyndt
X
X
Binaut
R
R
Lemaitre
V
V
Noël
L H
LH
Vanhille
P
P
D000368:Aged; D006801:Humans; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D014657:Vasculitis / Q000235:genetics*