title: [Effect of angong niuhuang pill as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic Encephalopathy].
abstract: OBJECTIVE
  To evaluate the clinical efficacy and safety of angong niuhuang pill (ANP) as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic encephalopathy (NHIE).
  
  
  METHODS
  Thirty-nine neonates with NHIE in the control group were treated with conventional treatment, and 58 in the treated group were administered orally ANP additionally, and relative indexes were observed.
  
  
  RESULTS
  The improvement of aspects such as recovery of consciousness, muscular tension, and primitive reflex and disappearance of convulsion, in the treated group was better than that in the control group (P < 0.01).
  
  
  CONCLUSIONS
  ANP as an adjuvant treatment has a definite effect on NHIE, it can promote the recovery of patients, decrease the occurrence of sequelae and with high safety, therefore, is a drug feasible for clinical application.
authors.affiliation: Department of Pediatrics, The Second People's Hospital of Wenzhou, Zhejiang. suweidongwz@163.com
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Su
authors.forename: Yu-dan
authors.initials: YD
authors.lastname: Huang
authors.forename: Er-li
authors.initials: EL
authors.lastname: Qu
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Ye
authors.forename: Manhua
authors.initials: M
authors.lastname: Bao
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000188:drug therapy* / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal