[The effect of Bu Yang Huan Wu soup and Tong Mai soup on D-Di, PLC and Pagt of traumatic fracture].
OBJECTIVE
To research the effect of Bu Yang Huan Wu Soup (BYHWS) and Tong Mai Soup (TMS) within varieties on D-Di, PLC, Pagt of traumatic fracture.


METHODS
48 cases are choosen, those are femoral-fractured, age between 18 to 45-year-old and in level I - II of ASA. The cases were randomly arranged into 3 groups, 16 cases are in each group. Group I is the controlled one, it isn't used any medicine which affects cruor. Group II is used BYHWS. Group III is used TMS. Group II and III are used medicine for 7 days from the first day in hospital. All patients in 3 groups are checked D-Di, PLC, Pagt in blood in the first day and the seventh day,and their results are compared with the healthy adult's.


RESULTS
(1) Comparing the D-Di of all 3 groups with the healthy adult's on the second day, P <0.01. The D-Di value of group I and group III grows up in 7 days, group I's is higher than group III's, but both of them P > 0.01. Value of group II is decreased in 7 days, P < 0.05. (2)PLC of all 3 groups is compared with healthy adult's, P > 0.01. On the seventh day, PLC of group I and group III increase obviously, P < 0.01. Group II's increases to P <0.05. (3) Pagt of 1st day of 3 groups is compared with the healthy adult's, P <0.05. On the 7th day, Pagt increases,in group I P < 0.01, in group II P < 0. 05. in group III P > 0.01.


CONCLUSIONS
Pagt rises after traumatic fracture, the blood is in high-agglomerate situation. Chinese traditional medicine BYHWS and TMS can decrease the blood platelet assemble after trauma a certain extent.
Wu
Zhengjie
Z
Foshan Hospital of TCM, Guangdong Foshan.
Ou
Jinyan
J
Luo
Furong
F
Liao
Rongzong
R
Zhou
Shu
S
D000293:Adolescent; D000328:Adult; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D005264:Femoral Fractures / Q000188:drug therapy* / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D010976:Platelet Count; D013997:Time Factors
D004365:Drugs, Chinese Herbal; D005338:Fibrin Fibrinogen Degradation Products; D010975:Platelet Aggregation Inhibitors