title: Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence.
abstract: Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence.
authors.affiliation: College of Life Science and Technology, Guangxi University, 100 Daxue Road, Nanning, Guangxi 530004, People's Republic of China.
authors.forename: Dong-Jie
authors.initials: DJ
authors.lastname: Tang
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: He
authors.forename: Jia-Xun
authors.initials: JX
authors.lastname: Feng
authors.forename: Bao-Ren
authors.initials: BR
authors.lastname: He
authors.forename: Bo-Le
authors.initials: BL
authors.lastname: Jiang
authors.forename: Guang-Tao
authors.initials: GT
authors.lastname: Lu
authors.forename: Baoshan
authors.initials: B
authors.lastname: Chen
authors.forename: Ji-Liang
authors.initials: JL
authors.lastname: Tang
mesh_terms: D001483:Base Sequence; D017931:DNA Primers; D003998:Dicarboxylic Acids / Q000378:metabolism; D005943:Gluconeogenesis / Q000235:genetics*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010935:Plant Diseases / Q000382:microbiology; D018515:Plant Leaves / Q000382:microbiology; D011773:Pyruvates / Q000378:metabolism; D017384:Sequence Deletion; D014774:Virulence; D016959:Xanthomonas campestris / Q000235:genetics / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity*
chemical_list: D017931:DNA Primers; D003998:Dicarboxylic Acids; D011773:Pyruvates