Milk amyloid A: correlation with cellular indices of mammary inflammation in cows with normal and raised serum amyloid A.
This study compared concentrations of amyloid A in bovine milk with the cell-based indicators of intramammary inflammation, somatic cell count and California Mastitis Test. Mammary quarter data pertaining to 180 cows were categorised according to concentrations of serum amyloid A in the cow of origin. Ranked correlation, ranked regression and receiver operator characteristics all demonstrated acceptable agreement between milk amyloid A concentrations and cell-based indices. There were some indications of reduction in this agreement, in cows with raised concentrations of serum amyloid A. However, there were also indications that serum amyloid A did not significantly influence milk amyloid A. The results of the current study indicate that milk amyloid A exhibits good correlation with established cell-based indicators of intramammary inflammation.
O'Mahony
M C
MC
Department of Large Animal Clinical Studies, Faculty of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland. Michael.OMahony@ucd.ie
Healy
A M
AM
Harte
D
D
Walshe
K G
KG
Torgerson
P R
PR
Doherty
M L
ML
D000818:Animals; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D002417:Cattle; D005260:Female; D007249:Inflammation / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D008321:Mammary Glands, Animal / Q000473:pathology*; D008414:Mastitis, Bovine / Q000097:blood* / Q000175:diagnosis / Q000473:pathology*; D008892:Milk / Q000737:chemistry*; D012680:Sensitivity and Specificity; D000685:Serum Amyloid A Protein / Q000032:analysis*
D015415:Biomarkers; D000685:Serum Amyloid A Protein