Hydrolytic degradation behavior of biodegradable polyetheresteramide-based polyurethane copolymers.
In this article, a new kind of biodegradable polyetheresteramide-based polyurethane (PEEA-U) copolymers were prepared by the melt polycondensation method from epsilon-caprolactone, 6-aminocaproic acid, poly(ethylene glycol), and toluene diisocyanate. The water absorption of PEEA-U was affected strongly by the reaction time and the content of chain extender; and the hydrolytic degradation behavior of the copolymers was mainly determined by the reaction time, chain extender content, and the pH value of the degradation medium. Also, DSC, (1)H-NMR, and inherent viscosity were used to characterize the degradation behavior of the copolymers.
Liu
Caibing
C
College of Material Science and Engineering, Sichuan University, Chengdu, 610065, People's Republic of China.
Gu
Yingchun
Y
Qian
Zhiyong
Z
Fan
Linyu
L
Li
Jun
J
Chao
Guotao
G
Tu
Mingjing
M
Jia
Wenjuan
W
D020341:Absorbable Implants; D000577:Amides / Q000737:chemistry / Q000378:metabolism; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D001673:Biodegradation, Environmental; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry / Q000378:metabolism; D011140:Polyurethanes / Q000737:chemistry / Q000378:metabolism; D014867:Water / Q000378:metabolism
D000577:Amides; D001672:Biocompatible Materials; D011108:Polymers; D011140:Polyurethanes; D014867:Water