Renal transplantation in the elderly--the Irish experience.
BACKGROUND
The aim of this paper was to evaluate patient and kidney graft survival rates in renal transplant recipients and compare the outcomes between the different patient age groups.


METHODS
A retrospective review of all adult renal transplants performed at Beaumont Hospital between the years 1986-2001 was carried out. Patients were defined as 'elderly' if they were 65 years of age or older and 'younger' if less than 65 years at the time of transplantation. Patient and transplant graft survival rates were analysed for each age group.


RESULTS
Data were analysed on 1462 'younger' patients and 105 'elderly' renal transplant recipients. Estimated patient survival at 1, 5 and 10 years were 96%, 87% and 74% in the younger patient group compared to 85%, 59% and 33% in the elderly group. The adjusted graft survival rates (adjusted for death due to other causes and with a functioning graft in situ) for the younger group were 89%, 77% and 64% at one, five and ten years respectively, while for the elderly group, adjusted one, five and ten year survival rates were 89%, 83% and 70% respectively.


CONCLUSIONS
Although the elderly have a shorter life expectancy than the younger population they do benefit from renal transplantation similar to the younger recipients.
Giblin
L
L
Irish Renal Transplant Registry, Department of Nephrology, Beaumont Hospital, Beaumont Road, Dublin 9.
Hollander
M
M
Little
D
D
Hickey
D
D
Donohoe
J
J
Walshe
J J
JJ
Dorman
A
A
O'Kelly
P
P
Conlon
P J
PJ
D000367:Age Factors; D000368:Aged; D005260:Female; D006085:Graft Survival; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D016030:Kidney Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D014180:Transplantation / Q000401:mortality*; D016896:Treatment Outcome