title: Chemokine control of lymphocyte trafficking: a general overview.
abstract: Chemokines are a large family of small, generally secreted polypeptides which guide lymphocyte movement throughout the body by controlling integrin avidity and inducing migration. Here, we look at recent, exciting findings on chemokine function throughout lymphocyte development and co-ordinated T and B cell migration during immune responses. Finally, we will review data on the regional control of immunity by tissue-specific chemokine receptors on effector/memory lymphocytes.
authors.affiliation: Theodor Kocher Institute, University of Bern, Freiestr. 1, 3012 Bern, Switzerland. jstein@tki.unibe.ch
authors.forename: Jens V
authors.initials: JV
authors.lastname: Stein
authors.forename: César
authors.initials: C
authors.lastname: Nombela-Arrieta
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D018925:Chemokines / Q000276:immunology*; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D006801:Humans; D008211:Lymphocyte Cooperation / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D018925:Chemokines