title: Prevention of neonatal sepsis.
abstract: Neonatal sepsis is a leading infectious cause of infant mortality. While use of intrapartum antibiotic prophylaxis in the United States has led to dramatic declines in perinatal sepsis caused by the bacteria group B streptococcus, interventions to prevent perinatal sepsis due to other causes have not yet been clearly defined. This article synthesizes information on neonatal sepsis disease burden, trends, and risk factors and reviews current and potential approaches to neonatal sepsis prevention.
authors.affiliation: Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Mailstop, C-23 Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Schrag
authors.forename: Anne
authors.initials: A
authors.lastname: Schuchat
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D005260:Female; D006801:Humans; D015994:Incidence; D007226:Infant Mortality / Q000639:trends; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D018743:Perinatal Care / Q000379:methods; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D013292:Streptococcus agalactiae; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents