Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia.
Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.
Dungerwalla
M
M
Section of Haemato-Oncology, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.
Osuji
N
N
Waldman
A D
AD
Al Jehani
F
F
Mehta
A
A
Tailor
R
R
Taylor
R
R
Wotherspoon
A
A
Cogill
G
G
Matutes
E
E
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D018450:Disease Progression; D005625:Frontal Lobe / Q000601:surgery; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D010166:Palliative Care; D014057:Tomography, X-Ray Computed
D000998:Antiviral Agents; D007372:Interferons