APE-type non-LTR retrotransposons: determinants involved in target site recognition.
Non-long terminal repeat (Non-LTR) retrotransposons represent a diverse and widely distributed group of transposable elements and an almost ubiquitous component of eukaryotic genomes that has a major impact on evolution. Their copy number can range from a few to several million and they often make up a significant fraction of the genomes. The members of the dominating subtype of non-LTR retrotransposons code for an endonuclease with homology to apurinic/apyrimidinic endonucleases (APE), and are thus termed APE-type non-LTR retrotransposons. In the last decade both the number of identified non-LTR retrotransposons and our knowledge of biology and evolution of APE-type non-LTR retrotransposons has increased tremendously.
Zingler
N
N
Paul-Ehrlich-Institut, Langen, Germany.
Weichenrieder
O
O
Schumann
G G
GG
D018626:Retroelements; D020079:Terminal Repeat Sequences
D018626:Retroelements