title: A prospective study on trypan blue capsule staining under air vs under viscoelastic.
abstract: OBJECTIVE
  To compare the safety and effectiveness of trypan blue capsule staining under air vs under viscoelastic.
  
  
  METHODS
  A total of 52 consecutive patients planned for phacoemulsification of white mature cataract were randomly assigned to trypan blue staining under air or under viscoelastic. Perioperative changes in best-corrected visual acuity (BCVA), central corneal thickness (CCT), and endothelial cell density (ECD) were compared between the two groups. The differences in operating and phacoemulsification times, staining pattern, and complications between the two groups were also recorded.
  
  
  RESULTS
  Phacoemulsification of white mature cataract was performed in 50 (96%) eyes. The median preoperative BCVA was hand movement. No significant differences in the baseline characteristics were found between the two groups. At 3 months after phacoemulsification, the median BCVA improved to 0.8. The mean CCT returned to preoperative level by 1 month postoperatively and the mean ECD loss was 11.9% 3 months postoperatively. No significant differences in median BCVA, mean phacoemulsification and operation times, mean CCT, and mean ECD were found between the two groups.
  
  
  CONCLUSIONS
  Trypan blue staining of the anterior lens capsule under air or under viscoelastic were similarly effective and safe methods for the phacoemulsification of white mature cataract.
authors.affiliation: Department of Ophthalmology and Visual Science, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
authors.forename: V W Y
authors.initials: VW
authors.lastname: Wong
authors.forename: T Y Y
authors.initials: TY
authors.lastname: Lai
authors.forename: G K Y
authors.initials: GK
authors.lastname: Lee
authors.forename: P T H
authors.initials: PT
authors.lastname: Lam
authors.forename: D S C
authors.initials: DS
authors.lastname: Lam
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000388:Air; D002807:Chondroitin; D002809:Chondroitin Sulfates; D004396:Coloring Agents; D003315:Cornea / Q000166:cytology / Q000000981:diagnostic imaging; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid; D007903:Lens Capsule, Crystalline / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods; D011446:Prospective Studies; D013194:Staining and Labeling / Q000379:methods; D016896:Treatment Outcome; D014343:Trypan Blue; D014463:Ultrasonography; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D004338:Drug Combinations; C501944:chondroitin sulfate, sodium hyaluronate drug combination; D006820:Hyaluronic Acid; D002807:Chondroitin; D002809:Chondroitin Sulfates; D014343:Trypan Blue