Severe aplastic anemia associated with paroxysmal nocturnal hemoglobinuria and lymphoplasmacytic lymphoma.
An unusual case of aplastic anemia presenting in association with lymphoplasmacytic lymphoma and paroxysmal nocturnal hemoglobinuria is discussed. An insult to the hematological stem cell compartment may result in multiple pathological entities, potentially influencing our approach to the treatment of hematological clonal disorders.
Veidt
Robin G
RG
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, Maryland 21205, USA.
Ansari-Lari
Ali
A
Brodsky
Robert A
RA
D000368:Aged; D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000961:Antilymphocyte Serum / Q000008:administration & dosage / Q000627:therapeutic use; D019046:Bone Marrow Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D013997:Time Factors; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000188:drug therapy
D000961:Antilymphocyte Serum; D016572:Cyclosporine