title: Haploinsufficiency in multiploid colorectal cancer.
authors.forename: Minoru
authors.initials: M
authors.lastname: Toyota
authors.forename: Kohzoh
authors.initials: K
authors.lastname: Imai
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Shinomura
mesh_terms: D022981:Allelic Imbalance; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D019175:DNA Methylation; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D018450:Disease Progression; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D019656:Loss of Heterozygosity; D008297:Male; D009154:Mutation; D011003:Ploidies; D011379:Prognosis; D012680:Sensitivity and Specificity; D051901:Smad4 Protein; D015534:Trans-Activators / Q000235:genetics* / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; C497796:SMAD4 protein, human; D051901:Smad4 Protein; D015534:Trans-Activators