[Evaluation of the efficacy of miconazole nitrate shampoo for prevention against T. tonsurans infection].
We report the efficacy of miconazole nitrate shampoo (Furfur Shampoo) to prevent T. tonsurans infection.


METHODS
Experimental models were made from stratum corneum of healthy human heel or guinea pig skin. Before and/or after T. tonsurans was applied, samples were washed with miconazole nitrate shampoo, then inoculated on a Sabouraud culture plate.


RESULTS
Though miconazole nitrate shampoo did not eliminate T. tonsurans on the sample completely, the time required to develop the colony (9.9 days) was obviously extended (7.7 days by control).


CONCLUSIONS
We concluded that miconazole nitrate shampoo is a useful method of preventing T. tonsurans infection, and should be used every day (before/after the chance to infect).
Ninomiya
Junya
J
Department of Dermatology, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.
Ito
Yayoi
Y
Takiuchi
Iwao
I
D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage*; D006168:Guinea Pigs; D006801:Humans; D066298:In Vitro Techniques; D008825:Miconazole / Q000008:administration & dosage*; D014005:Tinea / Q000188:drug therapy / Q000517:prevention & control*
D000935:Antifungal Agents; D008825:Miconazole