[Pathophysiology of Barrett's esophagus--motility disorder of esophagus].
Barrett's esophagus is a premalignant condition of reflux esophagitis and the prevalence is increasing in western countries. Although pathogenesis of Barrett's esophagus is still unknown, several studies have indicated that Barrett's esophagus is related to increased acid reflux through decreased lower esophageal sphincter tone and reduced esophageal contractions. In this article recent studies of Barrett's esophagus on pathophysiology of esophageal motility is reviewed.
Haruma
Ken
K
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School.
Honda
Keisuke
K
Kamata
Tomoari
T
Kusunoki
Hiroaki
H
Sugiu
Kuniaki
K
Tanaka
Aki
A
Hata
Jiro
J
D001471:Barrett Esophagus / Q000209:etiology / Q000503:physiopathology*; D049630:Esophageal Sphincter, Lower / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000209:etiology; D005769:Gastrointestinal Motility; D006801:Humans; D009119:Muscle Contraction; D009129:Muscle Tonus; D009130:Muscle, Smooth / Q000503:physiopathology