title: Comparative overview of brain perfusion imaging techniques.
abstract: OBJECTIVE
  Numerous imaging techniques have been developed and applied to evaluate brain hemodynamics. Among these are positron emission tomography, single photon emission computed tomography, Xenon-enhanced computed tomography, dynamic perfusion computed tomography, MRI dynamic susceptibility contrast, arterial spin labeling, and Doppler ultrasound. These techniques give similar information about brain hemodynamics in the form of parameters such as cerebral blood flow or cerebral blood volume. All of them are used to characterize the same types of pathological conditions. However, each technique has its own advantages and drawbacks.
  
  
  RESULTS
  This article addresses the main imaging techniques dedicated to brain hemodynamics. It represents a comparative overview established by consensus among specialists of the various techniques.
  
  
  CONCLUSIONS
  For clinicians, this article should offer a clearer picture of the pros and cons of currently available brain perfusion imaging techniques and assist them in choosing the proper method for every specific clinical setting.
authors.affiliation: Department of Radiology, University of California, 505 Parnassus Ave, San Francisco, CA 94143-0628, USA. Max.Wintermark@radiology.ucsf.edu
authors.forename: Max
authors.initials: M
authors.lastname: Wintermark
authors.forename: Musa
authors.initials: M
authors.lastname: Sesay
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Barbier
authors.forename: Katalin
authors.initials: K
authors.lastname: Borbély
authors.forename: William P
authors.initials: WP
authors.lastname: Dillon
authors.forename: James D
authors.initials: JD
authors.lastname: Eastwood
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Glenn
authors.forename: Cécile B
authors.initials: CB
authors.lastname: Grandin
authors.forename: Salvador
authors.initials: S
authors.lastname: Pedraza
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Soustiel
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nariai
authors.forename: Greg
authors.initials: G
authors.lastname: Zaharchuk
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Caillé
authors.forename: Vincent
authors.initials: V
authors.lastname: Dousset
authors.forename: Howard
authors.initials: H
authors.lastname: Yonas
mesh_terms: D000368:Aged; D001921:Brain / Q000098:blood supply / Q000473:pathology*; D002138:Calibration; D002560:Cerebrovascular Circulation; D003287:Contrast Media / Q000494:pharmacology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000295:instrumentation / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000295:instrumentation / Q000379:methods*; D013113:Spin Labels; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*; D018608:Ultrasonography, Doppler / Q000295:instrumentation / Q000379:methods*; D014978:Xenon / Q000494:pharmacology
chemical_list: D003287:Contrast Media; D013113:Spin Labels; D014978:Xenon