DNA as a matrix of collagen fibrils.
In this paper we demonstrate that DNA binds to collagen directly to form DNA-collagen complex. Our model suggests that DNA, containing well-arranged phosphate groups, helps the collagen to make ordered aggregates-fibrils. During this process hydration shell of collagen triple helix destroys and stabilizes hydration shell of ds-DNA.
Mrevlishvili
George M
GM
Department of Physics, Tbilisi State University, Chavchavadze av. 3, Tbilisi 0128, Georgia. gmrevli@ictsu.tsu.edu.ge
Svintradze
David V
DV
D055592:Biophysical Phenomena; D001703:Biophysics; D003094:Collagen / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008962:Models, Theoretical; D008968:Molecular Conformation; D009690:Nucleic Acid Conformation; D010710:Phosphates / Q000737:chemistry
D010710:Phosphates; D003094:Collagen; D004247:DNA