Integration of cell adhesion reactions--a balance of forces?
The rearrangement of receptors by oligomeric adhesion molecules constitutes a configurational mechanism able to sculpture membranes and dislocate receptors from cytoplasmic anchorage. This provides a conceptual framework for complex cellular processes in mechanical terms, as a dynamic balance between extracellular and intracellular driving forces.
Schmidt
Otto
O
University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia. otto.schmidt@adelaide.edu.au
Schreiber
Andreas
A
D000818:Animals; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules / Q000378:metabolism; D002468:Cell Physiological Phenomena; D004705:Endocytosis; D008024:Ligands; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000502:physiology*
D015815:Cell Adhesion Molecules; D008024:Ligands; D011956:Receptors, Cell Surface