Identification of unique B/C recombinant strains of HIV-1 in the southern state of Karnataka, India.
We characterized the molecular nature of a large number of primary HIV-1 isolates in the four southern states of India. In addition to confirming a predominance of subtype C infection, for the first time we identified three B/C recombinant viruses in a subset of 115 samples. Unexpectedly, env sequences of two of the three B/C recombinants phylogenetically clustered with subtype B strains of the USA. The determination of the real incidence of the recombinant viruses is of importance.
Siddappa
Nagadenahalli Byrareddy
NB
Molecular Virology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560 064, India.
Dash
Prashanta Kumar
PK
Mahadevan
Anita
A
Desai
Anita
A
Jayasuryan
Narayana
N
Ravi
Vasanthapuram
V
Satishchandra
Parthasarathy
P
Shankar
Susarla K
SK
Ranga
Udaykumar
U
D000293:Adolescent; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D011995:Recombination, Genetic