title: Case of symptomatic propriospinal myoclonus evolving toward acute "myoclonic status".
abstract: Propriospinal myoclonus is a rare motor disorder consisting of involuntary spinal-generated muscular jerks. Here, we report a severe and uncommon case of propriospinal myoclonus that appeared after a vertebral fracture of T11. In this patient, the polysomnographic investigation showed continuing focal myoclonic activity in axial muscles during stable sleep and an acute progression into a myoclonic "status" associated with respiratory failure and loss of consciousness. It is necessary to consider this severe progression and support it with prompt emergency maneuvers and adequate pharmacotherapy.
authors.affiliation: Department of Neurology, Vita-Salute University, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele-Turro, Milan, Italy. manconi.mauro@hsr.it
authors.forename: Mauro
authors.initials: M
authors.lastname: Manconi
authors.forename: Barbara
authors.initials: B
authors.lastname: Sferrazza
authors.forename: Sandro
authors.initials: S
authors.lastname: Iannaccone
authors.forename: Antonio
authors.initials: A
authors.lastname: Massimo
authors.forename: Marco
authors.initials: M
authors.lastname: Zucconi
authors.forename: Luigi
authors.initials: L
authors.lastname: Ferini-Strambi
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D002998:Clonazepam / Q000627:therapeutic use; D018450:Disease Progression; D004576:Electromyography / Q000379:methods; D004831:Epilepsies, Myoclonic / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology / Q000528:radiation effects; D005133:Eye Movements / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000187:drug effects / Q000503:physiopathology / Q000528:radiation effects; D009431:Neural Conduction / Q000528:radiation effects; D016103:Spinal Fractures / Q000150:complications / Q000473:pathology; D013127:Spinal Nerves / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology*; D050781:Transcranial Magnetic Stimulation / Q000379:methods
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam