title: Universal leukocyte reduction: Is it appropriate medical practice or not?
abstract: This article discusses the evidence for the generally accepted uses of leukocyte-reduced blood and the controversy over leukocyte reduction and transfusion-related immunomodulation. A perspective is provided on the continued need for leukocyte reduction on the part of all patients in the United States.
authors.affiliation: Cell Therapy at Pall Medical, East Hills, NY 11548, USA. Judy_angelbeck@pall.com
authors.forename: Judy H
authors.initials: JH
authors.lastname: Angelbeck
authors.forename: Girolamo A
authors.initials: GA
authors.lastname: Ortolano
mesh_terms: D001803:Blood Transfusion / Q000379:methods / Q000592:standards; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000517:prevention & control / Q000635:transmission; D019317:Evidence-Based Medicine; D005334:Fever / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods / Q000592:standards; D007518:Isoantibodies / Q000276:immunology; D007937:Leukapheresis / Q000379:methods / Q000592:standards; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology / Q000821:virology; D009026:Mortality; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D065227:Transfusion Reaction
chemical_list: D007518:Isoantibodies