title: APE-type non-LTR retrotransposons: determinants involved in target site recognition.
abstract: Non-long terminal repeat (Non-LTR) retrotransposons represent a diverse and widely distributed group of transposable elements and an almost ubiquitous component of eukaryotic genomes that has a major impact on evolution. Their copy number can range from a few to several million and they often make up a significant fraction of the genomes. The members of the dominating subtype of non-LTR retrotransposons code for an endonuclease with homology to apurinic/apyrimidinic endonucleases (APE), and are thus termed APE-type non-LTR retrotransposons. In the last decade both the number of identified non-LTR retrotransposons and our knowledge of biology and evolution of APE-type non-LTR retrotransposons has increased tremendously.
authors.affiliation: Paul-Ehrlich-Institut, Langen, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Zingler
authors.forename: O
authors.initials: O
authors.lastname: Weichenrieder
authors.forename: G G
authors.initials: GG
authors.lastname: Schumann
mesh_terms: D018626:Retroelements; D020079:Terminal Repeat Sequences
chemical_list: D018626:Retroelements