title: [Argon plasma coagulation in Barrett's esophagus].
abstract: Argon plasma coagulation (APC) is noncontact electrocoagulation technique that creates tissue damage. Recently, it has been reported that Barrett's esophagus and Barrett's adenocarcinoma in situ could be successfully managed by APC. The aims of this treatment are to prevent the developing of adenocarcinoma and to promote the restitution of normal squamous epithelium. Combined antireflux surgery or proton pump inhibitor therapy are indispensable to this treatment. Shorter length of Barrett's epithelium and normalization in pH with PPI treatment were the independent predictors of sustained long-term restitution of squamous epithelium. In patient with Barrett's esophagus, APC offers an effective, minimally invasive alternative to other treatments previously performed.
authors.affiliation: Surgery for Organ Function and Biological Regulation, Nippon Medical School.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nomura
authors.forename: Kiyohiko
authors.initials: K
authors.lastname: Yamashita
authors.forename: Masao
authors.initials: M
authors.lastname: Miyashita
authors.forename: Takashi
authors.initials: T
authors.lastname: Tajiri
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology / Q000517:prevention & control; D001128:Argon / Q000627:therapeutic use*; D001471:Barrett Esophagus / Q000150:complications / Q000601:surgery*; D003131:Combined Modality Therapy; D004564:Electrocoagulation / Q000379:methods*; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D004938:Esophageal Neoplasms / Q000209:etiology / Q000517:prevention & control; D005764:Gastroesophageal Reflux / Q000150:complications / Q000601:surgery; D006801:Humans; D054328:Proton Pump Inhibitors
chemical_list: D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D001128:Argon