Hydrogen peroxide mouth rinse: an analgesic post-tonsillectomy.
OBJECTIVE
To compare the analgesic efficacy of hydrogen peroxide (H2O2) mouth rinse with control for post-tonsillectomy pain management.


METHODS
Double-blinded, prospective, randomized, controlled clinical trial.


METHODS
Thirty-seven patients from 5 to 14 years old undergoing electrocautery tonsillectomy were randomized to either the H2O2 mouth rinse or the water rinse (control) group. For 14 days, patients recorded pain levels twice daily using a visual analogue scale. Analgesic uses, as well as any complications, were also noted by the patients.


RESULTS
Thirty-seven patients completed the study, 21 in the treatment group and 16 in the control group. Mean postoperative days of pain were 10.3 and 8.3, respectively, and differed significantly (p = .008). Mean postoperative days of analgesic use were 9.0 and 6.7, respectively, and differed significantly (p = .005). Only one incidence of postoperative hemorrhage occurred in the study group.


CONCLUSIONS
In our study, the H2O2 mouth rinse does not provide a better analgesic effect than the water rinse for post-tonsillectomy pain relief.
Chacra
Zahi Abou
ZA
Division of Otolaryngology, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec.
Manoukian
John J
JJ
Al-Qahtani
Khaled
K
Al-Eisa
Mohamed
M
Balys
Rick
R
Hagr
Abderrahman
A
Tewfik
Ted L
TL
Schloss
Melvin D
MD
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use*; D008297:Male; D009067:Mouthwashes; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D014068:Tonsillectomy
D000891:Anti-Infective Agents, Local; D009067:Mouthwashes; D006861:Hydrogen Peroxide