Thermal stability of hepatitis E virus.
The thermal stability of virulent hepatitis E virus (HEV) and hepatitis A virus (HAV) was compared. Fecal suspensions of virus were heated to temperatures between 45 degrees C and 70 degrees C, and residual infectivity was determined in a cell culture system that was permissive for both viruses. Although HEV was less stable than was HAV, some HEV would most likely survive the internal temperatures of rare-cooked meat.
Emerson
Suzanne U
SU
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8009, USA. semerson@niaid.nih.gov
Arankalle
Vidya A
VA
Purcell
Robert H
RH
D002460:Cell Line; D005243:Feces / Q000821:virology; D005516:Food Microbiology; D006506:Hepatitis A / Q000635:transmission / Q000821:virology; D030041:Hepatitis A virus / Q000254:growth & development*; D016751:Hepatitis E / Q000635:transmission / Q000821:virology; D016752:Hepatitis E virus / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D008856:Microscopy, Fluorescence