Highly chemoselective addition of amines to epoxides in water.
Aminolysis of a variety of epoxides by aliphatic and aromatic amines in water, in the absence of any catalyst with high yields, is reported. Beta-amino alcohols were formed under mild conditions with high selectivity and in excellent yields. [reaction: see text]
Azizi
Najmodin
N
Department of Chemistry, Sharif University of Technology, P.O. Box 11465-9516, Tehran, Iran.
Saidi
Mohammad R
MR