title: Stupor and coma: pathophysiology of hypoxia--ontogenetic aspects.
abstract: There are several levels of O2 deprivation with different possibilities of adaptation and compensation. All of them appear to be highly conservative in phylogenesis and are active early in ontogenetic development. The coordinated structural and functional responses to systemic and/or local hypoxia form the basis for individual adaptation to environmental requirements and pathological threat.
authors.affiliation: Institute for Pathophysiology and Pathobiochemistry, Universitätsklinikum, Friedrich Schiller University, D-07740 Jena, Germany. Reinhard.Bauer@mti.uni-jena.de
authors.forename: Reinhard
authors.initials: R
authors.lastname: Bauer
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D003128:Coma / Q000209:etiology*; D006801:Humans; D000860:Hypoxia / Q000150:complications / Q000503:physiopathology*; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism*; D012039:Regional Blood Flow / Q000502:physiology; D013997:Time Factors
chemical_list: D010100:Oxygen