Extent of myocardial non-compaction: comparison between MRI and echocardiographic evaluation.
BACKGROUND
Non-compaction of the left ventricular myocardium is an important cause of cardiomyopathy. There is no clear consensus about its diagnostic criteria or the diagnostic test of choice. MRI is increasingly used in the pediatric cardiac field because of its superior and objective image quality.


OBJECTIVE
To compare the echocardiographic and MRI findings in four patients with recently diagnosed ventricular non-compaction.


METHODS
We compared the extent of myocardial involvement shown at MRI and echocardiography in four individuals, two patients with echocardiographic diagnosis of left ventricular non-compaction, and two family members of one of the patients.


RESULTS
In all patients, MRI showed wider area of involvement than echocardiography. A definite diagnosis was entertained in only two patients by echocardiography but in all by MRI. Cine imaging was diagnostic of the disease in all patients. Black-blood pool imaging with double-inversion recovery sequence also helped to visualize the abnormal areas by showing slow flow artifacts in the four- and two-chamber images.


CONCLUSIONS
MRI provided better delineation of the extent of the abnormal trabeculation in patients with non-compaction of the left ventricular myocardium. It was particularly useful when the myocardial involvement was subtle, as in the asymptomatic family members.
Alhabshan
Fahad
F
Department of Pediatrics, Division of Cardiology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Smallhorn
Jeffrey F
JF
Golding
Fraser
F
Musewe
Norman
N
Freedom
Robert M
RM
Yoo
Shi-Joon
SJ
D000293:Adolescent; D002312:Cardiomyopathy, Hypertrophic / Q000151:congenital* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D018487:Ventricular Dysfunction, Left / Q000151:congenital* / Q000175:diagnosis*