title: Novel copper(II) homobinuclear macrocyclic complexes: cyclic voltammetry, biological properties and spectral studies.
abstract: A series of five new copper(II) macrocyclic complexes have been synthesized by template condensation. The bonding and stereochemistry of the complexes have been characterized by elemental analysis, molar conductance, magnetic susceptibility, IR, UV-visible, EPR spectral studies and electrochemical properties. g-Values are calculated for all of the complexes in polycrystalline form as well as in DMSO solution. The magnetic and spectral data indicate square planar geometry for all the complexes. Cyclic voltammograms for all the complexes are similar and involve two quasi-reversible redox processes. Cu(II)Cu(II)<=>Cu(II)Cu(I)<=>Cu(I)Cu(I). Their biological properties have also been studied. The macrocyclic complexes show more anti-bacterial than controlled one. The anti-bacterial activities of the compounds were tested against Streptococcus fecalis and Escherichia coli with different concentrations.
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, J.L. Nehru Marg, New Delhi 110002, India. schandra_00@yahoo.com
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.forename: Nidhi
authors.initials: N
authors.lastname: Gupta
authors.forename: Rachna
authors.initials: R
authors.lastname: Gupta
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D013293:Enterococcus faecalis / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D008024:Ligands; D047028:Macrocyclic Compounds; D008280:Magnetics; D019216:Metals, Heavy; D008956:Models, Chemical; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011199:Potentiometry; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014466:Ultraviolet Rays
chemical_list: D000900:Anti-Bacterial Agents; D008024:Ligands; D047028:Macrocyclic Compounds; D019216:Metals, Heavy; D003300:Copper