title: Incidence of carbapenem resistant nonfermenting gram negative bacilli from patients with respiratory infections in the intensive care units.
abstract: Resistance to carbapenems is commonly seen in nonfermenting gram negative bacilli (NFGNB). We document herein the prevalence of carbapenem resistance in NFGNB isolated from patients with respiratory tract infections in the intensive care units (ICUs). A total of 460 NFGNB were isolated from 606 endotracheal aspirate specimens during January through December 2003, of which 56 (12.2%) were found to be resistant to imipenem and meropenem. Of these, 24 (42.8%) were Pseudomonas aeruginosa , 8 (14.2%) were Acinetobacter spp. and 24 (42.8%) were other NFGNB. Stringent protocols such as antibiotic policies and resistance surveillance programs are mandatory to curb these bacteria in ICU settings
authors.affiliation: Department of Clinical Microbiology, Christian Medical College, Vellore - 632 004, Tamil Nadu, India.
authors.forename: P
authors.initials: P
authors.lastname: Gladstone
authors.forename: P
authors.initials: P
authors.lastname: Rajendran
authors.forename: K N
authors.initials: KN
authors.lastname: Brahmadathan
mesh_terms: D015780:Carbapenems / Q000494:pharmacology* / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007362:Intensive Care Units; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D018440:beta-Lactam Resistance
chemical_list: D015780:Carbapenems