title: Toward rapid, "green", predictable microwave-assisted synthesis.
abstract: Continuous and batch microwave reactors were constructed for efficient, "green" synthesis with low-boiling solvents at high temperature in closed vessels. Capabilities for rapid heating and cooling, concurrent heating and cooling, and differential heating facilitated novel chemical reactions and processes. Commercial microwave systems based on these developments are available. Times required for conventional reactions typically are decreased by 2-3 orders of magnitude. Green processes also have resulted through use of less or no catalyst, readily recyclable solvents, or media and yields that are often higher than normal. Complementary interactive software for calculating optimal conditions was developed.
authors.affiliation: ARC Special Research Centre for Green Chemistry, Monash University, Clayton, Victoria 3800, Australia.
authors.forename: Brett A
authors.initials: BA
authors.lastname: Roberts
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Strauss
mesh_terms: D002384:Catalysis; D003080:Cold Temperature; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006358:Hot Temperature; D008872:Microwaves; D009930:Organic Chemicals / Q000138:chemical synthesis*; D004364:Pharmaceutical Preparations; D012984:Software; D012997:Solvents / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
chemical_list: D009930:Organic Chemicals; D004364:Pharmaceutical Preparations; D012997:Solvents