A mild and environmentally friendly scandium(III) trifluoromethanesulfonate-catalyzed synthesis of bis(3'-indolyl)alkanes and bis(3'-indolyl)-1-deoxyalditols.
Bis(3'-indolyl)alkanes and bis(3'-indolyl) derivatives containing a 1-deoxyalditol moiety were synthesized in the presence of 5 mol% of scandium(III) trifluoromethanesulfonate [Sc(OTf)3] in CH3CN or EtOH-H2O mixture as a solvent from room temperature to 70 degrees C in good yields (78-97%).
Sato
Shingo
S
Faculty of Engineering, Yamagata University, 4-3-16 Jonan, Yonezawa-shi, Yamagata 992-8510, Japan. shingo-s@yz.yamagata-u.ac.jp
Sato
Toshihiro
T
D000473:Alkanes / Q000138:chemical synthesis*; D002384:Catalysis; D008698:Mesylates; D012538:Scandium; D013402:Sugar Alcohols / Q000138:chemical synthesis*
D000473:Alkanes; D008698:Mesylates; D013402:Sugar Alcohols; C012077:trifluoromethanesulfonic acid; D012538:Scandium