The T348M mutated form of cryopyrin is associated with defective lipopolysaccharide-induced interleukin 10 production in CINCA syndrome.
Bihl
T
T
Vassina
E
E
Boettger
M K
MK
Goldbach-Mansky
R
R
Seitz
M
M
Villiger
P M
PM
Simon
H U
HU
D000328:Adult; D001327:Autoimmune Diseases / Q000235:genetics*; D002352:Carrier Proteins / Q000235:genetics*; D006801:Humans; D007249:Inflammation / Q000235:genetics*; D016753:Interleukin-10 / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000276:immunology; D008297:Male; D009154:Mutation; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D013577:Syndrome
D002352:Carrier Proteins; D008070:Lipopolysaccharides; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human; D016753:Interleukin-10