title: Indole-5-phenylcarbamate derivatives as human non-pancreatic secretory phospholipase A2 inhibitor.
abstract: The synthesis of the human non-pancreatic secretory phospholipase A2 inhibitor (IC(50)=1.81+/-0.59 microM) is reported.
authors.affiliation: State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Physical Chemistry and College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. liuying@pku.edu.cn
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Han
authors.forename: Chang-kang
authors.initials: CK
authors.lastname: Huang
authors.forename: Xin
authors.initials: X
authors.lastname: Hao
authors.forename: Lu-Hua
authors.initials: LH
authors.lastname: Lai
mesh_terms: D054501:Group II Phospholipases A2; D006801:Humans; D007700:Kinetics; D008958:Models, Molecular; D048448:Phenylcarbamates / Q000737:chemistry / Q000494:pharmacology*; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D054467:Phospholipases A2; D013050:Spectrometry, Fluorescence
chemical_list: D048448:Phenylcarbamates; D010741:Phospholipases A; D054501:Group II Phospholipases A2; D054467:Phospholipases A2