Derivatives of 2-mercaptobenzenesulphonamide. X. Synthesis of 1-dialkylaminoalkyl-2-(2-mercaptobenzenesulphonyl)guanidines with potential pharmacological activity.
Synthesis of 2-(4-R(1)-5-R(2)-2-mercaptobenzenesulphonyl)derivatives of 1-(dialkylaminoalkyl)-3-isobutylguanidine (III b-l) and 1,3-di(2-dialkylaminoethyl)guanidine (IV-V) as well as subsequent S-2-aminoethylation reaction VI a-h, VII a-b have been described.
Brzozowski
Z
Z
Department of Drug Technology, School of Medicine, 107 J. Hallera Str., 80-416 Gdańsk, Poland.
Sławiński
J
J
D006146:Guanidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000494:pharmacology*
D006146:Guanidines; D013449:Sulfonamides