title: Isolated uncontrolled hypertension at home and in the office among treated hypertensive patients from the J-HOME study.
abstract: OBJECTIVE
  To evaluate the current status of blood pressure (BP) control as measured at home and in the office, as well as to clarify and compare the prevalence and characteristics of isolated uncontrolled hypertension as measured at home (home hypertension) and in the office (office hypertension).
  
  
  METHODS
  A cross-sectional study.
  
  
  METHODS
  Primary care offices in Japan.
  
  
  METHODS
  A sample of 3400 patients with essential hypertension (mean age, 66 years; males, 45%) receiving antihypertensive treatment.
  
  
  RESULTS
  Overall, the mean home systolic BP (SBP)/diastolic BP (DBP) was 140/82 mmHg, and the mean office SBP/DBP was 143/81 mmHg. Of the 3400 subjects, 19% had controlled hypertension (home SBP/DBP < 135/85 mmHg and office SBP/DBP < 140/90 mmHg), 23% had isolated uncontrolled home hypertension (home SBP/DBP >/= 135/85 mmHg and office SBP/DBP < 140/90 mmHg), 15% had isolated uncontrolled office hypertension (home SBP/DBP < 135/85 mmHg and office SBP/DBP < 140/90 mmHg), and 43% had uncontrolled hypertension (home SBP/DBP >/= 135/85 mmHg and office SBP/DBP >/= 140/90 mmHg). Compared to controlled hypertension, factors associated with isolated uncontrolled home hypertension included obesity, relatively higher office SBP, habitual drinking, and the use of two or more prescribed antihypertensive drugs. Compared to uncontrolled hypertension, factors associated with isolated uncontrolled office hypertension included female gender, lower body mass index, and relatively lower office SBP.
  
  
  CONCLUSIONS
  The use of all four, three of four, or all three predictive factors might be useful for the clinician to suspect isolated uncontrolled home or office hypertension.
authors.affiliation: Department of Clinical Pharmacology and Therapeutics, Graduate School of Pharmaceutical Science and Medicine, Tohoku University, 980-8574 Sendai, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Obara
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Ohkubo
authors.forename: Jin
authors.initials: J
authors.lastname: Funahashi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuya
authors.forename: Kei
authors.initials: K
authors.lastname: Asayama
authors.forename: Hirohito
authors.initials: H
authors.lastname: Metoki
authors.forename: Takuya
authors.initials: T
authors.lastname: Oikawa
authors.forename: Junichiro
authors.initials: J
authors.lastname: Hashimoto
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Totsune
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imai
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods / Q000592:standards; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology* / Q000503:physiopathology; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009819:Office Visits; D010820:Physicians / Q000706:statistics & numerical data; D015995:Prevalence
chemical_list: D000959:Antihypertensive Agents