title: Infectious adult rhinosinusitis: etiology, diagnosis, and management principles.
abstract: Rhinosinusitis represents a complicated and multifaceted group of diseases that is generally classified into the categories of acute and chronic. Although many instances of acute rhinosinusitis lasting longer than 7 days are thought to be of bacterial origin, most are thought to be inflammatory rather than infectious. The contribution of infectious organisms to the pathogenesis of chronic rhinosinusitis is an area of controversy and active investigation. Examples of these areas of investigation include biofilms, osteitis, and bacterial superantigens. This review discusses the role of infectious organisms in both acute and chronic sinusitis, with special focus on the etiology and diagnosis of these conditions, and includes a discussion of principles of their management.
authors.affiliation: Department of Otolaryngology, University of Western Ontario, London, ON.
authors.forename: Erin D
authors.initials: ED
authors.lastname: Wright
authors.forename: Saul
authors.initials: S
authors.lastname: Frenkiel
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D018441:Biofilms; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D006801:Humans; D017410:Practice Guidelines as Topic; D012220:Rhinitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012852:Sinusitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents