title: Identification of a new HLA-B variant, HLA-B*5615.
abstract: A new HLA-B allele, B*5615, has been identified in a Caucasian individual by sequence-based typing. This allele shows a sequence identical to that of HLA-B*5601 except for two nucleotide substitutions that cause a change from TTA to TAC at codon 116 and an amino acidic change from Leucine to Tyrosine in the mature protein.
authors.affiliation: Dipartimento Trasfusionale e di Riferimento per i Trapianti di Organi, Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena-Fondazione IRCCS di Natura Pubblica, Milano, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Frison
authors.forename: E
authors.initials: E
authors.lastname: Longhi
authors.forename: A E
authors.initials: AE
authors.lastname: de Arias
authors.forename: E
authors.initials: E
authors.lastname: Andreini
authors.forename: M
authors.initials: M
authors.lastname: Scalamogna
authors.forename: F
authors.initials: F
authors.lastname: Poli
mesh_terms: D000483:Alleles; D001483:Base Sequence; D003062:Codon; D005091:Exons; D005260:Female; D015235:HLA-B Antigens / Q000235:genetics*; D006650:Histocompatibility Testing; D006720:Homozygote; D006801:Humans; D007930:Leucine / Q000235:genetics; D008969:Molecular Sequence Data; D017354:Point Mutation; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D014443:Tyrosine / Q000235:genetics
chemical_list: D003062:Codon; D015235:HLA-B Antigens; C506471:HLA-B*56:15 antigen; D014443:Tyrosine; D007930:Leucine