title: Ahmed valve implantation for uncontrolled pediatric uveitic glaucoma.
abstract: OBJECTIVE
  We sought to evaluate the safety and efficacy of Ahmed valve implantation for the management of glaucoma associated with chronic uveitis in pediatric patients.
  
  
  METHODS
  A retrospective chart review was conducted of 6 pediatric patients (7 eyes) who underwent Ahmed valve implantation because of refractory uveitic glaucoma. Intraocular pressure (IOP) reduction, preoperative and postoperative visual acuities, the number of hypotensive medications required, and complications associated with the operation were evaluated.
  
  
  RESULTS
  Mean follow-up was 36.8 months (range, 6-60). At the last visit, all 7 eyes had IOPs between 9 and 18 mm Hg (average, 12.1). IOP reduction averaged 69.6% (P = 0.0005, paired t-test). The number of hypotensive agents was reduced from an average of 3 to an average of 0.71 medicines per eye (P = 0.001). The only complication was hemorrhagic choroidal detachment postoperatively in two eyes; both resolved within one month.
  
  
  CONCLUSIONS
  For children with good immunomodulatory control of their inflammation and appropriate follow-up, Ahmed valve implantation can be an effective and safe procedure for treating pediatric uveitic glaucoma.
authors.affiliation: Massachusetts Eye Research and Surgery Institute and Ocular Immunology and Uveitis Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Chrysanthi
authors.initials: C
authors.lastname: Kafkala
authors.forename: Alla
authors.initials: A
authors.lastname: Hynes
authors.forename: John
authors.initials: J
authors.lastname: Choi
authors.forename: Aysen
authors.initials: A
authors.lastname: Topalkara
authors.forename: C Stephen
authors.initials: CS
authors.lastname: Foster
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005901:Glaucoma / Q000209:etiology / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007429:Intraocular Pressure; D008297:Male; D011183:Postoperative Complications; D019919:Prosthesis Implantation / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000150:complications; D014792:Visual Acuity
chemical_list: D007166:Immunosuppressive Agents