Dengue 2 genotypes in the state of Oaxaca, Mexico.
To genetically characterize dengue 2 (DEN-2) viruses in Oaxaca, Mexico, the C protein, and a portion of the prM protein genes of 8 isolates from the 2001 DEN epidemic were sequenced. The sequences were compared to those of prototype DEN-2 viruses from various parts of the world. Phylogenetic analysis suggested that the 2001 isolates of DEN-2 were of the American/Asian genotype and were most similar to the Jamaica and Venezuelan isolates MARA3, LARD1996 and LARD1910. Molecular analyses confirmed the origin of the isolates. This study indicates that DEN-2 strains of American/Asian genotype probably from Southeast Asian are circulating in Oaxaca.
Cisneros
A
A
Sección de Estudios de Postrado e Investigación de la Escuela Nacional de Medicina y Homeopatía del IPN, México.
Díaz-Badillo
A
A
Cruz-Martínez
G
G
Tovar
R
R
Ramírez-Palacios
L R
LR
Jiménez-Rojas
F
F
Beaty
B
B
Black
W C
WC
de Lourdes Muñoz
M
M
D000818:Animals; D002460:Cell Line; D003715:Dengue / Q000453:epidemiology / Q000821:virology; D003716:Dengue Virus / Q000235:genetics* / Q000302:isolation & purification; D005838:Genotype; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D010802:Phylogeny; D012367:RNA, Viral / Q000302:isolation & purification; D017386:Sequence Homology, Amino Acid; D014764:Viral Proteins / Q000235:genetics
D012367:RNA, Viral; D014764:Viral Proteins