Mechanistic approaches to chemoprevention of mutation and cancer.
This is the eighth special issue of 'Mutation Research' to focus on antimutagenesis and anticarcinogenesis. It covers a wide range of mechanisms from prevention of cancer initiation by antimutagens through to inhibition of tumour angiogenesis and selective estrogen receptor modulators. New screening methods and new biomarkers are also elucidated. There is increasing reason to believe that the long-term use of a combination of anticarcinogens, over an extended time span, may provide a realistic prospect of reducing the current burden of human cancers.
Ferguson
Lynnette R
LR
The University of Auckland, School of Medical Sciences, Faculty of Medical and Health Sciences, Discipline of Nutrition/ACSRC, Private Bag 92019, Auckland 1000, New Zealand.
Bronzetti
Giorgio
G
De Flora
Silvio
S
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology / Q000627:therapeutic use; D016587:Antimutagenic Agents / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D016296:Mutagenesis; D009369:Neoplasms / Q000235:genetics / Q000517:prevention & control*
D016588:Anticarcinogenic Agents; D016587:Antimutagenic Agents