title: Photodynamic therapy for choroidal neovascularization on late-onset fundus flavimaculatus.
abstract: OBJECTIVE
  To report the features of three consecutive cases of patients affected with late-onset fundus flavimaculatus (FFM) complicated with choroidal new vessels (CNV) and treated with photodynamic therapy (PDT).
  
  
  METHODS
  Retrospective interventional case series.
  
  
  METHODS
  Three unrelated women (70- to 74-year-old) presented with unilateral decrease of central vision. Diagnosis of FFM and unilateral CNV was made after fundus examination and fluorescein angiography (FA). PDT was performed on the basis of FA features.
  
  
  RESULTS
  One to three PDTs were needed for the treatment of CNV. At the end of follow-up (15-24 months), no leakage was present and visual acuity was improved in these three cases.
  
  
  CONCLUSIONS
  Occurrence of CNV is a rare event in FFM. In these three eyes, PDT successfully stopped the progression of CNV and blocked leakage. We suggest considering PDT as a treatment for CNV in patients affected with FFM.
authors.affiliation: Clinique Ophtalmologique Universitaire de Créteil, Créteil, France. eric.souied@chicreteil.fr
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
authors.forename: Dominique
authors.initials: D
authors.lastname: Pawlak
authors.forename: Michel
authors.initials: M
authors.lastname: Algan
authors.forename: David
authors.initials: D
authors.lastname: Sayag
authors.forename: Gabriel
authors.initials: G
authors.lastname: Coscas
authors.forename: Gisele
authors.initials: G
authors.lastname: Soubrane
mesh_terms: D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012164:Retinal Diseases / Q000150:complications / Q000188:drug therapy*; D012189:Retrospective Studies
chemical_list: D017319:Photosensitizing Agents