title: Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata.
abstract: Investigation of the aerial parts of Ouratea sulcata led to the isolation of a biflavonoid named sulcatone A, together with the known compounds, 3-hydroxy-2,3-dihydroapigenyl-[I-4',O,II-3']-dihydrokaempferol, amentoflavone, lophirone A, agathisflavone, stigmasterol and stigmasteryl-3-O-beta-D-glucopyranoside. The structure of the compound was assigned as apigenyl-[I-4',O,II-3']-dihydrokaempferol, by means of spectroscopic analysis. Sulcatone A and 3-hydroxy-2,3-dihydroapigenyl-[I-4',O,II-3']-dihydrokaempferol exhibited significant in vitro antimicrobial activities against a range of microorganisms.
authors.affiliation: Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon. epegny@uycdc.uninet.cm
authors.forename: Dieudonné Emmanuel
authors.initials: DE
authors.lastname: Pegnyemb
authors.forename: Josephine Ngo
authors.initials: JN
authors.lastname: Mbing
authors.forename: Alex
authors.initials: A
authors.lastname: de Théodore Atchadé
authors.forename: Raphael Ghogomu
authors.initials: RG
authors.lastname: Tih
authors.forename: Beiban Lucas
authors.initials: BL
authors.lastname: Sondengam
authors.forename: Alain
authors.initials: A
authors.lastname: Blond
authors.forename: Bernard
authors.initials: B
authors.lastname: Bodo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D044946:Biflavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D044949:Kaempferols / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D043842:Ochnaceae / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry*
chemical_list: C506798:3-hydroxy-2,3-dihydroapigenyl-(I-4',O,II-3')-dihydrokaempferol; D000900:Anti-Bacterial Agents; D044946:Biflavonoids; D044949:Kaempferols; C506797:sulcatone A