title: Diffusion of published cost-utility analyses in the field of health policy and practice.
abstract: OBJECTIVE
  The diffusion of cost-utility analyses (CUAs) through the medical literature was examined, documenting visible patterns and determining how they correspond with expectations about the diffusion of process innovations.
  
  
  METHODS
  This study used 539 CUAs from a registry. It includes data elements comprising year of publication, the research center in which the study was performed, the clinical area covered by the CUA, and the specific journal. Finally, each paper was assigned to a journal type that could be one of the three categories: health services research, general medicine, or clinical specialty.
  
  
  RESULTS
  When the average number of publications is plotted against time, the plot reveals an S-shaped curve. It appears that, whereas CUAs initially were published more frequently in general medical or health services research journals, there was a clear increase in the diffusion of CUA into subspecialty journals over time. The concentration ratio for research centers as measured by the Herfindhal-Hirschman Index decreased over time.
  
  
  CONCLUSIONS
  The spread of CUA through the medical literature follows patterns identified for the diffusion of other new technologies and processes. Future research should focus on what impact this spread has had on the practice of medicine and formulation of health policy.
authors.affiliation: Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283, USA. seema.sonnad@uphs.upenn.edu
authors.forename: Seema S
authors.initials: SS
authors.lastname: Sonnad
authors.forename: Dan
authors.initials: D
authors.lastname: Greenberg
authors.forename: Allison B
authors.initials: AB
authors.lastname: Rosen
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Neumann
mesh_terms: D003362:Cost-Benefit Analysis; D004470:Economics, Medical; D006291:Health Policy / Q000191:economics* / Q000639:trends; D006302:Health Services Research / Q000191:economics* / Q000639:trends; D006801:Humans; D033181:Information Dissemination; D008511:Medicine / Q000639:trends; D010506:Periodicals as Topic / Q000191:economics / Q000639:trends; D013038:Specialization