title: Statics and dynamics of single DNA molecules confined in nanochannels.
abstract: The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.
authors.affiliation: Physics Department, Princeton University, New Jersey 08544, USA.
authors.forename: Walter
authors.initials: W
authors.lastname: Reisner
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Morton
authors.forename: Robert
authors.initials: R
authors.lastname: Riehn
authors.forename: Yan Mei
authors.initials: YM
authors.lastname: Wang
authors.forename: Zhaoning
authors.initials: Z
authors.lastname: Yu
authors.forename: Michael
authors.initials: M
authors.lastname: Rosen
authors.forename: James C
authors.initials: JC
authors.lastname: Sturm
authors.forename: Stephen Y
authors.initials: SY
authors.lastname: Chou
authors.forename: Erwin
authors.initials: E
authors.lastname: Frey
authors.forename: Robert H
authors.initials: RH
authors.lastname: Austin
mesh_terms: D010582:Bacteriophage lambda / Q000737:chemistry / Q000235:genetics; D004279:DNA, Viral / Q000737:chemistry* / Q000276:immunology; D036103:Nanotechnology / Q000379:methods; D043942:Nanotubes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D004279:DNA, Viral; D012822:Silicon Dioxide