title: The SET-domain protein superfamily: protein lysine methyltransferases.
abstract: The SET-domain protein methyltransferase superfamily includes all but one of the proteins known to methylate histones on lysine. Histone methylation is important in the regulation of chromatin and gene expression.
authors.affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. scd@sanger.ac.uk
authors.forename: Shane C
authors.initials: SC
authors.lastname: Dillon
authors.forename: Xing
authors.initials: X
authors.lastname: Zhang
authors.forename: Raymond C
authors.initials: RC
authors.lastname: Trievel
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Cheng
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D011495:Histone-Lysine N-Methyltransferase / Q000737:chemistry* / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008745:Methylation; D008958:Models, Molecular; D005810:Multigene Family; D017434:Protein Structure, Tertiary
chemical_list: D011495:Histone-Lysine N-Methyltransferase