Catalytic asymmetric desymmetrization of cyclic meso-1,3- and 1,4-diols by a phosphinite derivative of quinidine.
Asymmetric monobenzoylation reactions of cyclic meso-1,3- and 1,4-diols were catalyzed by a phosphinite derivative of quinidine to afford the corresponding monobenzoylated diol with good yield and enantioselectivity. [reaction: see text]
Mizuta
Shinya
S
Department of Functional Polymer Science, Shinshu University, Tokida Ueda 386-8567, Japan.
Tsuzuki
Takeo
T
Fujimoto
Tetsuya
T
Yamamoto
Iwao
I