title: Detection and assessment of coronary artery anomalies by three-dimensional magnetic resonance coronary angiography.
abstract: BACKGROUND
  Coronary artery anomalies (CAAs) are a relatively rare condition usually diagnosed in vivo by conventional angiography. In the past few years Magnetic resonance coronary angiography (MRCA) has been used to detect CAAs and found to be highly accurate. No data is available regarding the ability of MRCA to detect previously not suspected anomalies.
  
  
  METHODS
  We prospectively analyzed the origin and course of 336 patients undergoing a diagnostic Cardiovascular magnetic resonance (CMR) study. After the completion of a standard examination a navigator-echo 3D-MRCA low-quality scan was used in all the cases to rule out CAAs. The high-quality MRCA was applied only if an abnormal coronary arterial tree was seen.
  
  
  RESULTS
  Nineteen patients with CAAs (12 men, 7 women; mean age, 53+/-18 years) were identified by MRCA. Six out of the 19 CAAs subjects had already been detected by other means (coronary angiography in 5, and transesophageal echocardiography in 1 case). However in none of them a complete anatomical assessment was achieved. In 13 patients CAAs were an unexpected and new finding. MRCA was able to assess the origin and proximal course of the anomalous artery in all the cases.
  
  
  CONCLUSIONS
  MRCA is able to detect the presence and anomalous course of CAAs. Besides offering precise information about already suspected CAAs, MRCA can identify anomalies previously not suspected. This study suggests a potential role for MRCA as a screening tool for CAAs in young patients with angina, ventricular arrhythmias, or unexplained syncope as well as in highly competitive athletes.
authors.affiliation: Clinica Medica e Cardiologia, Azienda Universitaria Ospedaliera Careggi, Viale Morgagni 85, 50123 Florence, Italy. Casolo@Virgilio.it
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Casolo
authors.forename: Jacopo
authors.initials: J
authors.lastname: Del Meglio
authors.forename: Luigi
authors.initials: L
authors.lastname: Rega
authors.forename: Rosanna
authors.initials: R
authors.lastname: Manta
authors.forename: Massimo
authors.initials: M
authors.lastname: Margheri
authors.forename: Natale
authors.initials: N
authors.lastname: Villari
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Gensini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003330:Coronary Vessel Anomalies / Q000175:diagnosis*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies