Therapeutic HIV vaccines: an update.
The goal of therapeutic immunization in HIV infection is to induce strong and sustained immune responses against HIV. Several arguments suggest that the immune system may contain HIV replication in the long term before declining. The potency on new antiviral regimens in clinic has provided an opportunity to improve the control of the virus replication by the immune system. In clinical terms, this might allow patients to delay or to stop antiviral therapy and to minimize the duration of the exposition to antiviral drugs.
Lévy
Yves
Y
Service d'immunologie Clinique, Hopital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France. yves.levy@hmn.aphp.fr
D016915:AIDS Vaccines / Q000276:immunology*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D018791:CD4 Lymphocyte Count; D006678:HIV / Q000502:physiology*; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D014779:Virus Replication / Q000187:drug effects*
D016915:AIDS Vaccines