title: Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction.
abstract: Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed Huisgen [3 + 2] dipolar cycloaddition reaction.
authors.affiliation: Institute for Molecules and Materials, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.
authors.forename: A J Ton
authors.initials: AJ
authors.lastname: Dirks
authors.forename: Sander S
authors.initials: SS
authors.lastname: van Berkel
authors.forename: Nikos S
authors.initials: NS
authors.lastname: Hatzakis
authors.forename: Joost A
authors.initials: JA
authors.lastname: Opsteen
authors.forename: Floris L
authors.initials: FL
authors.lastname: van Delft
authors.forename: Jeroen J L M
authors.initials: JJ
authors.lastname: Cornelissen
authors.forename: Alan E
authors.initials: AE
authors.lastname: Rowan
authors.forename: Jan C M
authors.initials: JC
authors.lastname: van Hest
authors.forename: Floris P J T
authors.initials: FP
authors.lastname: Rutjes
authors.forename: Roeland J M
authors.initials: RJ
authors.lastname: Nolte
mesh_terms: D001386:Azides / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D049329:Nanostructures; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry; D011137:Polystyrenes / Q000737:chemistry; D011506:Proteins / Q000138:chemical synthesis / Q000737:chemistry; D013499:Surface Properties; D013501:Surface-Active Agents / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D001386:Azides; D010455:Peptides; D011137:Polystyrenes; D011506:Proteins; D013501:Surface-Active Agents; D003300:Copper