Facile synthesis of beta-organotellurobutenolides via electrophilic tellurolactonization of alpha-allenoic acids.
We report a convenient and highly efficient method for the synthesis of beta-organotellurobutenolides by the aryltellurenyl halides-induced electrophilic tellurolactonization of alpha-allenoic acids under mild conditions. The resulting beta-organotellurobutenolides can be utilized as precursors for versatile butenolide derivatives through a substitution reaction with organocuprate reagent or Pd/Cu(I)-catalyzed cross-coupling with terminal alkyne.
Xu
Qing
Q
Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou 310028, P. R. China.
Huang
Xian
X
Yuan
Jingqi
J