title: Changing patterns of colorectal cancer in China over a period of 20 years.
abstract: OBJECTIVE
  To determine whether any changes have occurred on the patterns of colorectal cancer in China.
  
  
  METHODS
  Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology.
  
  
  RESULTS
  From 1980s to 1990s, the mean age of the colorectal cancer patients has increased. The percentage of the female patients rose. The distribution of colorectal carcinoma shows a predominance of rectal cancer. However, the proportion of proximal colon cancer (including transverse and ascending colon) increased significantly accompanied by a decline in the percentage of rectal cancer. Similarity in the percentage of distal colon cancer between two decades was revealed. In the 1990s, statistically more Stage B patients were found than those in 1980s. In addition, databases show a significant decrease in the Stage D cases. The proportion of adenocarcinoma increased, but the mucinous adenocarcinoma decreased during two decades.
  
  
  CONCLUSIONS
  These findings indicate that the pattern of colorectal cancer in China has been changing. Especially, a proximal shift due to the increasing proportion of ascending and transverse colon cancer has occurred in China.
authors.affiliation: Department of Surgery, Beijing Cancer Hospital, Peking University School of Oncology, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Gu
mesh_terms: D002681:China / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000453:epidemiology; D017678:Sex Distribution; D013997:Time Factors