A rare association: Castleman's disease and pemphigus vulgaris.
Castleman disease is a reactive lymph node hyperplasia of unknown origin that often involving the thorax although it may involve all parts of the body. It is usually seen in young adults and presents an asymptomatic course. It is usually located to anterior and middle mediastinum. Pemphigus vulgaris is a bullous skin disease in which immune mechanisms take place in the pathogenesis. Mouth and oropharynx are the most commonly involved structures. IgG antibodies against the epidermal intracellular structures are essential in the diagnosis. We have wanted to discuss a 28 years old female with the literature review since the association between pemphigus vulgaris and Castleman's disease is rare.
Uskül
Bahadir
B
Süreyyapaşa Training Hospital for Chest and Cardiovascular Diseases, Department of Chest Diseases, Istanbul, Turkey. tbuskul@hotmail.com
Ertuğrul
Müyesser
M
Selvi
Ahmet
A
Mihmanli
Aydanur
A
Zindanci
Ilkin
I
Türker
Hatice
H
D000328:Adult; D005871:Castleman Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010392:Pemphigus / Q000175:diagnosis / Q000473:pathology; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed