A new minor triterpene saponin from kaixin-san prescription.
A new minor oleanane-type saponin, ginsenoside-R(OA) (1), has been isolated from the extract of Kaixin-San, a prescription composed of Panax ginseng and other medicinal herbs, together with 15 known ginsenosides. The structure of 1 was established as 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl oleanolic acid 28-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside by chemical and spectroscopic evidence. In addition, the presence of ginsenoside-R(OA) in ginseng was confirmed by HPLC-ESI-MS.
Liu
Jiang-Yun
JY
Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
Xiao
Sheng-Yuan
SY
Shang
Wei-Fen
WF
Xu
Li-Zhen
LZ
Yang
Shi-Lin
SL
D002851:Chromatography, High Pressure Liquid; D013058:Mass Spectrometry; D005894:Panax / Q000737:chemistry*; D010940:Plant Proteins / Q000737:chemistry* / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry
D010940:Plant Proteins; C104839:ginseng pentadecapeptide, Panax ginseng