Gamma irradiation does not affect 7-day storage of platelet concentrates.
OBJECTIVE
Extension of storage of leucocyte-reduced platelet concentrates (LR-PCs) to 7 days has recently been introduced, but the effect of gamma irradiation on in vitro parameters was unknown.


METHODS
A paired experiment was carried out, with gamma irradiation on day 1 or day 5 with 25 Gy, and no irradiation served as a reference.


RESULTS
Measurements during storage up to 8 days after blood collection showed no significant differences of irradiated LR-PCs vs. the control.


CONCLUSIONS
Irradiation, either on day 1 or day 5, had no effect on platelet quality during a 7-day storage period.
van der Meer
P F
PF
Sanquin Blood Bank North West region, Amsterdam, the Netherlands. p.vandermeer@sanquin.nl
Pietersz
R N I
RN
D001792:Blood Platelets / Q000166:cytology* / Q000528:radiation effects; D001793:Blood Preservation / Q000379:methods*; D005720:Gamma Rays; D006801:Humans; D047589:Leukocyte Reduction Procedures; D017713:Platelet Transfusion / Q000295:instrumentation / Q000379:methods; D013048:Specimen Handling; D013997:Time Factors