title: Clinical features and diagnosis of primary central nervous system lymphoma.
abstract: This article reviews the clinical features of primary central nervous system lymphoma (PCNSL) in immunocompetent and immunocompromised patients. Clinical presentation, differential diagnosis, diagnostic testing, and staging evaluation in both immunocompetent and AIDS patients who have PCNSL are discussed. The differing role of biopsy in these two populations also is addressed.
authors.affiliation: Stephen E. and Catherine Pappas Center for Neuro-Oncology, Yawkey 9E, Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: April
authors.initials: A
authors.lastname: Fitzsimmons
authors.forename: Kristen
authors.initials: K
authors.lastname: Upchurch
authors.forename: Tracy
authors.initials: T
authors.lastname: Batchelor
mesh_terms: D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000628:therapy; D009367:Neoplasm Staging