title: Anthraquinone derivatives as a new family of protein photocleavers.
abstract: Certain anthraquinones, which are present in many biologically important natural products, effectively and randomly cleaved proteins (BSA or Lyso) during photoirradiation using a long wavelength UV light without any further additives. It was also found that this ability could be improved by the attachment of a suitable substituent into the anthraquinone core skeleton.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
authors.forename: Akane
authors.initials: A
authors.lastname: Suzuki
authors.forename: Masashi
authors.initials: M
authors.lastname: Hasegawa
authors.forename: Maiko
authors.initials: M
authors.lastname: Ishii
authors.forename: Shuichi
authors.initials: S
authors.lastname: Matsumura
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Toshima
mesh_terms: D000880:Anthraquinones / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D010777:Photochemistry; D011506:Proteins / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014466:Ultraviolet Rays
chemical_list: D000880:Anthraquinones; D011506:Proteins