Relaxation dynamics of a single DNA molecule.
The relaxation of a single DNA molecule is studied. The experimental system consists of optical tweezers and a micron-sized bead that is tethered to the bottom of the sample by a single double-stranded DNA molecule. The bead slows down the DNA relaxation from a strongly stretched configuration such that it is passing through stretched equilibrium states. This allows for a theoretical description of the relaxation trajectory, which is in good agreement with experiment.
Goshen
E
E
Department of Physics and The Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel.
Zhao
W Z
WZ
Carmon
G
G
Rosen
S
S
Granek
R
R
Feingold
M
M
D003198:Computer Simulation; D004247:DNA / Q000032:analysis / Q000737:chemistry* / Q000648:ultrastructure*; D004548:Elasticity; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007700:Kinetics; D008846:Micromanipulation / Q000379:methods*; D008956:Models, Chemical; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010812:Physical Stimulation / Q000379:methods; D013314:Stress, Mechanical
D004247:DNA