Olanzapine versus risperidone in the treatment of post-psychotic depression in schizophrenic patients.
OBJECTIVE
To compare the efficacy of two atypical antipsychotic drugs, olanzapine and risperidone, in schizophrenic patients with post-psychotic depression.


RESULTS
A clinically significant decrease of MADRS scores occurred in patients treated with both drugs for 8 weeks.


CONCLUSIONS
Atypical antipsychotic drugs may be particularly appropriate when treating schizophrenic patients with depression.
Dollfus
Sonia
S
Department of psychiatry, Centre Esquirol, Centre Hospitalier et Universitaire, avenue de la Côte de Nacre, Caen, 14000, France. dollfus-s@chu-caen.fr
Olivier
Véronique
V
Chabot
Benoît
B
Déal
Cécile
C
Perrin
Elena
E
D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use; D003863:Depression / Q000175:diagnosis* / Q000209:etiology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D011618:Psychotic Disorders / Q000523:psychology*; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D012720:Severity of Illness Index
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D018967:Risperidone; D000077152:Olanzapine