Dendrite development: a surprising origin.
Neurons extend elaborate dendrites studded with spines. Unexpectedly, this cellular sculpting is regulated by the origin recognition complex -- the core machinery for initiating DNA replication.
Ehlers
Michael D
MD
Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA. ehlers@neuro.duke.edu
D000199:Actins / Q000378:metabolism; D000818:Animals; D003599:Cytoskeleton / Q000378:metabolism; D004261:DNA Replication; D003712:Dendrites / Q000378:metabolism*; D004331:Drosophila melanogaster; D006801:Humans; D051738:Origin Recognition Complex / Q000378:metabolism*
D000199:Actins; D051738:Origin Recognition Complex