Rosai-Dorfman disease: unusual cause of diffuse and massive retroperitoneal lymphadenopathy.
Rosai-Dorfman disease (RDD), originally described as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Patients usually present with massive cervical lymphadenopathy. However other nodal sites (mediastinal and inguinal) are also frequently involved. The retro-peritoneum is an infrequent site of involvement. This uncommon entity should also be included in the list of differential diagnoses of diffuse and massive lymphadenopathy, which includes includes infectious/granulomatous conditions, lymphomatous and metastatic disease.
Sodhi
K S
KS
Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (P.G.I.M.E.R.), Chandigarh, 160012 India.
Suri
S
S
Nijhawan
R
R
Kang
M
M
Gautam
V
V
D000328:Adult; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D012187:Retroperitoneal Space; D014057:Tomography, X-Ray Computed