title: Hydrolytic degradation behavior of biodegradable polyetheresteramide-based polyurethane copolymers.
abstract: In this article, a new kind of biodegradable polyetheresteramide-based polyurethane (PEEA-U) copolymers were prepared by the melt polycondensation method from epsilon-caprolactone, 6-aminocaproic acid, poly(ethylene glycol), and toluene diisocyanate. The water absorption of PEEA-U was affected strongly by the reaction time and the content of chain extender; and the hydrolytic degradation behavior of the copolymers was mainly determined by the reaction time, chain extender content, and the pH value of the degradation medium. Also, DSC, (1)H-NMR, and inherent viscosity were used to characterize the degradation behavior of the copolymers.
authors.affiliation: College of Material Science and Engineering, Sichuan University, Chengdu, 610065, People's Republic of China.
authors.forename: Caibing
authors.initials: C
authors.lastname: Liu
authors.forename: Yingchun
authors.initials: Y
authors.lastname: Gu
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qian
authors.forename: Linyu
authors.initials: L
authors.lastname: Fan
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Guotao
authors.initials: G
authors.lastname: Chao
authors.forename: Mingjing
authors.initials: M
authors.lastname: Tu
authors.forename: Wenjuan
authors.initials: W
authors.lastname: Jia
mesh_terms: D020341:Absorbable Implants; D000577:Amides / Q000737:chemistry / Q000378:metabolism; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D001673:Biodegradation, Environmental; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry / Q000378:metabolism; D011140:Polyurethanes / Q000737:chemistry / Q000378:metabolism; D014867:Water / Q000378:metabolism
chemical_list: D000577:Amides; D001672:Biocompatible Materials; D011108:Polymers; D011140:Polyurethanes; D014867:Water