Motion-onset VEPs reflect long maturation and early aging of visual motion-processing system.
Pattern-reversal and motion-onset visual evoked potentials (VEPs) were simultaneously tested in a group of 70 healthy subjects between the ages of 6-60 years to verify suspected differences in maturation and aging dynamics of the pattern and motion processing subsystems of the visual pathway. The motion-onset VEPs displayed dramatic configuration development and shortening of latencies up to 18 years of age (correl. coeff. -0.85; p < 0.001) and systematic prolongation from about 20 years of age (correl. coeff. 0.70; p < 0.001). This confirms long-lasting maturation of the magnocellular system and/or motion processing cortex and their early age related changes. Less significant changes of pattern-reversal VEPs in the tested age range can be interpreted as a sign of early maturation of the parvocellular system and its enhanced functional endurance in the elderly.
Langrová
J
J
Department of Pathophysiology, Charles University-Faculty of Medicine, Simkova 870, 500 38 Hradec Králové, Czech Republic. langrovaJ@lfhk.cuni.cz
Kuba
M
M
Kremlácek
J
J
Kubová
Z
Z
Vít
F
F
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology* / Q000523:psychology; D002648:Child; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology*