title: Triple coronary bypass in a child with homozygous familial hypercholesterolemia.
abstract: Here we report triple coronary bypass procedure in a 12-year-old girl with familial homozygous hypercholesterolemia and extensive coronary atherosclerosis. She had successful cardiopulmonary resuscitation at home by her father 4 months before the operation. Total cholesterol level was 1300 mg/dL initially without antilipidemic treatment. Extensive three vessel disease with right coronary proximal stenosis and left coronary ostial stenoses was determined by angiography. Left internal thoracic artery, left radial artery, and saphenous vein grafts were used for coronary revascularization. Saphenous vein graft to right posterior descending artery, radial artery graft to obtuse marginal artery, and LITA to left anterior descending artery anastomoses were performed consecutively. Ten months after the operation, she is in good condition under intensive antilipidemic therapy and weekly lipid apheresis.
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. mehmetkaplan@superonline.com
authors.forename: Mehmet Salih
authors.initials: MS
authors.lastname: Bilal
authors.forename: Numan Ali
authors.initials: NA
authors.lastname: Aydemir
authors.forename: Nihat
authors.initials: N
authors.lastname: Cine
authors.forename: Ahmet
authors.initials: A
authors.lastname: Celebi
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kaplan
mesh_terms: D002648:Child; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D005260:Female; D006720:Homozygote; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications* / Q000235:genetics*; D016896:Treatment Outcome