title: Invasive aspergillosis involving multiple paranasal sinuses--a case report.
abstract: A case of invasive multiple paranasal sinus aspergillosis with bony involvement is reported. A young immunocompetent lady presented with bilateral nasal obstruction due to polyps. Radiologically and histopathologically a fungal cause was kept a possibility, and the diagnosis of Aspegillus fumigatus was established by demonstration of acute angle branching septate hyphae on direct wet mount and repeated isolation in culture. Patient responded favourably to surgical excision of polyps and oral itraconazole post operatively.
authors.affiliation: Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh - 171 001, India.
authors.forename: S
authors.initials: S
authors.lastname: Agarwal
authors.forename: A
authors.initials: A
authors.lastname: Kanga
authors.forename: V
authors.initials: V
authors.lastname: Sharma
authors.forename: D R
authors.initials: DR
authors.lastname: Sharma
authors.forename: M L
authors.initials: ML
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D001232:Aspergillus fumigatus / Q000254:growth & development*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D009298:Nasal Polyps / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D010254:Paranasal Sinus Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology / Q000601:surgery
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole