Extranodal Rosai-Dorfman disease of bone, subcutaneous tissue and paranasal sinus mucosa with a review of its pathogenesis.
We report an unusual case of extranodal Rosai-Dorfman disease presenting in a 36-year-old man with lesions of bone, subcutaneous tissue of the arm and maxillary sinus mucosa unassociated with lymphadenopathy or systemic symptoms. These lesions appeared metachronously within a 6-month period. The diagnostic light microscopic and immunohistochemical findings and pathogenesis of this interesting disease are discussed.
Yoon
Angela J
AJ
Department of Pathology, Division of Surgical Pathology, College of Physicians and Surgeons, Columbia University Medical Center, 630 West 168th Street 1574, New York, NY 10032, USA. mp11@columbia.edu
Parisien
May
M
Feldman
Frieda
F
Young-In Lee
Francis
F
D000328:Adult; D001132:Arm; D005360:Fibula; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008443:Maxillary Sinus; D011859:Radiography; D020545:Respiratory Mucosa; D040521:Subcutaneous Tissue