Bone reactions to longstanding functional load at implants: an experimental study in dogs.
OBJECTIVE
The aims of the present investigation were (i) to study marginal bone level alterations following implant installation, abutment connection and functional loading and (ii) to analyse bone tissue reactions to functional load.


METHODS
Six beagle dogs, about 1-year old, were used. All mandibular pre-molars were extracted. Three months later four implants of the Astra Tech Implants Dental System were installed in one side of the mandible and four standard fixtures of the Brånemark System were placed in the contralateral side of the mandible. Abutment connection was performed 3 months later and a plaque control programme was initiated. Three months after abutment connection fixed partial dentures (FPDs) made in gold were cemented to the maxillary canines and pre-molars. FPDs were also connected to the three posterior implants in each side of the mandible, while the mesial implant in each side was used as an unloaded control. Radiographs were obtained from all implant sites following implant installation, abutment connection and FPD placement. Ten months after the FPD placement the radiographic examination was repeated. The animals were sacrificed and biopsies from all implant sites were obtained and prepared for histological analysis.


RESULTS
The radiographic analysis revealed that largest amount of bone loss occurred following implant installation and abutment connection and that this loss was more pronounced at Brånemark than at Astra implants. The bone level alterations that were observed at implants exposed to 10 months of functional load in both implant systems were small and did not differ from control sites. The histological analysis revealed that implants exposed to functional load exhibited a higher degree of bone-to-implant contact than control implants in both implant systems.


CONCLUSIONS
It is suggested that functional load at implants may enhance osseointegration and does not result in marginal bone loss.
Berglundh
T
T
Department of Periodontology, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden. berglundh@odontologi.gu.se
Abrahamsson
I
I
Lindhe
J
J
D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D000818:Animals; D000044:Dental Abutments / Q000009:adverse effects; D003758:Dental Implantation, Endosseous / Q000009:adverse effects* / Q000379:methods; D015921:Dental Implants / Q000009:adverse effects*; D019094:Dental Prosthesis, Implant-Supported / Q000009:adverse effects; D003830:Denture, Partial, Fixed / Q000009:adverse effects; D004285:Dogs; D008334:Mandible / Q000000981:diagnostic imaging / Q000601:surgery; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011859:Radiography; D013997:Time Factors; D016474:Weight-Bearing
D015921:Dental Implants