The use of an insuflon device for the administration of G-CSF in pediatric cancer patients.
In pediatric oncology, granulocyte colony-stimulating factor (G-CSF) is applied with the aim of shortening neutropenic periods after chemotherapy and for mobilization of peripheral blood stem cells for apheresis procedures. G-CSF is administered, subcutaneously or intravenously, on a daily basis. An insuflon device for the administration of G-CSF was used in 29 patients for 93 G-CSF periods. Retrospective evaluation shows that this administration route is feasible, safe and preferred by young children rather than by teenagers with cancer.
de Jong
M E A
ME
Department of Pediatric Oncology/Hematology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Carbière
T
T
van den Heuvel-Eibrink
M M
MM
D000293:Adolescent; D000741:Anemia, Aplastic / Q000139:chemically induced / Q000517:prevention & control*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004867:Equipment Design; D004869:Equipment Safety; D005240:Feasibility Studies; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007275:Injections, Intravenous / Q000295:instrumentation; D007279:Injections, Subcutaneous / Q000295:instrumentation; D009369:Neoplasms / Q000188:drug therapy*; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D016179:Granulocyte Colony-Stimulating Factor