HLA genes in Mexican Teeneks: HLA genetic relationship with other worldwide populations.
The HLA allele frequency distribution of the Mexican Teenek Indians has been studied and compared with those of other First American Natives and worldwide populations (a total of 15694 chromosomes from 73 different populations were analyzed). This study corroborate the restricted HLA polymorphism in the Amerindian populations and demonstrate how the Amerindians show a relatively homogeneity as opposed to other First Native American groups. Finally, the present data support previous ones that state the lack of complete correlation between language and genetics in micro-environmental studies; Teenek Mayan language does not correspond with a close Mayan (Guatemala) relatedness.
Vargas-Alarcón
Gilberto
G
Department of Physiology and Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiología Ignacio Chávez, 14080 Mexico City, Mexico. gvargas63@yahoo.com
Hernández-Pacheco
Guadalupe
G
Moscoso
Juan
J
Pérez-Hernández
Nonanzit
N
Murguía
Luis Enrique
LE
Moreno
Almudena
A
Serrano-Vela
Juan Ignacio
JI
Granados
Julio
J
Arnaiz-Villena
Antonio
A
D000483:Alleles; D002877:Chromosomes, Human / Q000235:genetics*; D005787:Gene Frequency; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D007199:Indians, South American / Q000145:classification / Q000235:genetics*; D010802:Phylogeny; D011153:Population / Q000235:genetics*
D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II