[Effect of angong niuhuang pill as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic Encephalopathy].
OBJECTIVE
To evaluate the clinical efficacy and safety of angong niuhuang pill (ANP) as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic encephalopathy (NHIE).


METHODS
Thirty-nine neonates with NHIE in the control group were treated with conventional treatment, and 58 in the treated group were administered orally ANP additionally, and relative indexes were observed.


RESULTS
The improvement of aspects such as recovery of consciousness, muscular tension, and primitive reflex and disappearance of convulsion, in the treated group was better than that in the control group (P < 0.01).


CONCLUSIONS
ANP as an adjuvant treatment has a definite effect on NHIE, it can promote the recovery of patients, decrease the occurrence of sequelae and with high safety, therefore, is a drug feasible for clinical application.
Su
Wei-dong
WD
Department of Pediatrics, The Second People's Hospital of Wenzhou, Zhejiang. suweidongwz@163.com
Huang
Yu-dan
YD
Qu
Er-li
EL
Zhang
Yu
Y
Ye
Wen
W
Bao
Manhua
M
D001238:Asphyxia Neonatorum / Q000150:complications / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000188:drug therapy* / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D008517:Phytotherapy
D004365:Drugs, Chinese Herbal