title: Assessment of papillary muscle function in patients with inferior wall myocardial infarction using Doppler tissue imaging.
abstract: OBJECTIVE
  We sought to assess the relationship between infarct status and systolic contractile function of papillary muscle (PM) for patients with inferior wall myocardial infarction (MI).
  
  
  METHODS
  Peak systolic velocity (V) of posteromedial PM, systolic strain (epsilon) of posteromedial PM (epsilonPM), V of adjacent inferior wall, and of adjacent inferior wall (epsilonW) were calculated from color Doppler tissue imaging images obtained at apical views in 25 patients with inferior MI and in 13 healthy control subjects. All 25 patients with MI underwent magnetic resonance imaging to assess the infarct status of PM.
  
  
  RESULTS
  Compared with the control subjects, patients with MI had significantly lower V of adjacent inferior wall (5.0 +/- 0.8 vs 4.4 +/- 1.1 cm/s, P = .049) and V of posteromedial PM (4.9 +/- 0.8 vs 4.0 +/- 1.2 cm/s, P = .005), and less systolic deformation, as demonstrated by epsilonW (-17 +/- 3 vs -6 +/- 5%, P < .001) and epsilonPM (-24 +/- 5 vs -11 +/- 6%, P < .001). There was a weak positive correlation between epsilonW and epsilonPM (r = 0.393, P = .052) for patients with MI. Magnetic resonance imaging showed total infarct of PM in 14 patients (group A), with the remaining 11 revealing either normal perfusion or partial infarct of PM (group B). Although epsilonW was similar in groups A and B (-5 +/- 5% vs -8 +/- 6%, P = .20), epsilonPM was significantly lower in group B (-7 +/- 4% vs -16 +/- 4%, P = .004).
  
  
  CONCLUSIONS
  In patients with inferior wall MI, infarct status of the PM is variable and determines its systolic contractile function, which can be quantified by epsilon measurement using Doppler tissue imaging.
authors.affiliation: Division of Cardiology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, South Korea.
authors.forename: Soo-Jin
authors.initials: SJ
authors.lastname: Kang
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Lee
authors.forename: Jae-Kwan
authors.initials: JK
authors.lastname: Song
authors.forename: Kyung-Hyun
authors.initials: KH
authors.lastname: Do
authors.forename: Joon Beom
authors.initials: JB
authors.lastname: Seo
authors.forename: Tae-Hwan
authors.initials: TH
authors.lastname: Lim
authors.forename: Jong-Min
authors.initials: JM
authors.lastname: Song
authors.forename: Duk-Hyun
authors.initials: DH
authors.lastname: Kang
authors.forename: Young-Hak
authors.initials: YH
authors.lastname: Kim
authors.forename: Cheol Whan
authors.initials: CW
authors.lastname: Lee
authors.forename: Myeong-Ki
authors.initials: MK
authors.lastname: Hong
authors.forename: Seong-Wook
authors.initials: SW
authors.lastname: Park
authors.forename: Seung-Jung
authors.initials: SJ
authors.lastname: Park
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000503:physiopathology*; D018618:Echocardiography, Doppler, Color; D006801:Humans; D008279:Magnetic Resonance Imaging; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D010210:Papillary Muscles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D013599:Systole / Q000502:physiology*