title: Rosai-Dorfman disease: unusual cause of diffuse and massive retroperitoneal lymphadenopathy.
abstract: Rosai-Dorfman disease (RDD), originally described as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Patients usually present with massive cervical lymphadenopathy. However other nodal sites (mediastinal and inguinal) are also frequently involved. The retro-peritoneum is an infrequent site of involvement. This uncommon entity should also be included in the list of differential diagnoses of diffuse and massive lymphadenopathy, which includes includes infectious/granulomatous conditions, lymphomatous and metastatic disease.
authors.affiliation: Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (P.G.I.M.E.R.), Chandigarh, 160012 India.
authors.forename: K S
authors.initials: KS
authors.lastname: Sodhi
authors.forename: S
authors.initials: S
authors.lastname: Suri
authors.forename: R
authors.initials: R
authors.lastname: Nijhawan
authors.forename: M
authors.initials: M
authors.lastname: Kang
authors.forename: V
authors.initials: V
authors.lastname: Gautam
mesh_terms: D000328:Adult; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D012187:Retroperitoneal Space; D014057:Tomography, X-Ray Computed