title: High prevalence of viral genomes and inflammation in peripartum cardiomyopathy.
abstract: Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy.
authors.affiliation: Institute of Pathology, University Hospital of Tübingen, Germany. bdbueltm@med.uni-tuebingen.de
authors.forename: Burkhard D
authors.initials: BD
authors.lastname: Bültmann
authors.forename: Karin
authors.initials: K
authors.lastname: Klingel
authors.forename: Michael
authors.initials: M
authors.lastname: Näbauer
authors.forename: Diethelm
authors.initials: D
authors.lastname: Wallwiener
authors.forename: Reinhard
authors.initials: R
authors.lastname: Kandolf
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000821:virology*; D003587:Cytomegalovirus / Q000235:genetics; D004699:Endocardium / Q000821:virology; D005260:Female; D016679:Genome, Viral; D006321:Heart / Q000821:virology; D004854:Herpesvirus 4, Human / Q000235:genetics; D015654:Herpesvirus 6, Human / Q000235:genetics; D006801:Humans; D009205:Myocarditis / Q000821:virology; D016732:Parvovirus B19, Human / Q000235:genetics; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000821:virology*; D011644:Puerperal Disorders / Q000821:virology*