title: Multidisciplinary management of head and neck sarcomas.
abstract: BACKGROUND
  Head and neck sarcomas are extremely rare. This article reviews the management and outcomes in a multidisciplinary clinic.
  
  
  METHODS
  The records of 41 male and 19 female patients (mean age, 50 years) were reviewed. Forty percent underwent surgical resection only, 35% underwent surgery and adjuvant therapy, and 25% underwent radiotherapy and/or chemotherapy without surgery. Seventy-one percent had complete histologic clearance.
  
  
  RESULTS
  The mean follow-up was 3 years and 10 months, with an overall 5-year survival rate of 60%. Completeness of surgical excision was highly significant in determining 5-year local control (p < .025), and the addition of adjuvant radiotherapy had a major effect on local control, but only if complete surgical clearance had been achieved (p < .025). As expected, patients with more aggressive tumors had a significantly poorer overall prognosis, and achieving local control led to an enhanced 5-year survival (p < .025).
  
  
  CONCLUSIONS
  These tumors are best managed in multidisciplinary clinics, and the mainstay of treatment is wide local excision and planned postoperative adjuvant radiotherapy.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, United Kingdom. jcolville@cmki.org
authors.forename: R James
authors.initials: RJ
authors.lastname: Colville
authors.forename: Fraser
authors.initials: F
authors.lastname: Charlton
authors.forename: Charles G
authors.initials: CG
authors.lastname: Kelly
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Nicoll
authors.forename: Neil R
authors.initials: NR
authors.lastname: McLean
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality; D010348:Patient Care Team; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012509:Sarcoma / Q000401:mortality* / Q000628:therapy*; D015996:Survival Rate; D006113:United Kingdom / Q000453:epidemiology