title: Synthesis of 2,3-di- and 2,3,4-trisubstituted furans from 1,2-dioxines generated by an enyne-RCM/Diels-Alder reaction sequence.
abstract: An efficient method for the synthesis of 2,3- and 2,3,4-substituted furans starting from acyclic enynes was developed using an enyne-RCM/Diels-Alder reaction sequence. The reaction conditions for the transformation of 1,2-dioxines having an adjacent 1,2-oxazine ring into furans and the cleavage of N-O bonds are discussed.
authors.affiliation: Center for Bioactive Molecular Hybrids (CBMH) and Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Young-Keun
authors.initials: YK
authors.lastname: Yang
authors.forename: Jung-Hoon
authors.initials: JH
authors.lastname: Choi
authors.forename: Jinsung
authors.initials: J
authors.lastname: Tae
mesh_terms: D005663:Furans / Q000138:chemical synthesis*
chemical_list: D005663:Furans