Ibuprofen extrudate, a novel, rapidly dissolving ibuprofen formulation: relative bioavailability compared to ibuprofen lysinate and regular ibuprofen, and food effect on all formulations.
Klueglich
Matthias
M
Human Pharmacology Centre Ingelheim, Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Ring
Arne
A
Scheuerer
Stefan
S
Trommeshauser
Dirk
D
Schuijt
Chris
C
Liepold
Bernd
B
Berndl
Gunther
G
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000493:pharmacokinetics*; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D005260:Female; D018565:Food-Drug Interactions; D006801:Humans; D007052:Ibuprofen / Q000031:analogs & derivatives* / Q000737:chemistry / Q000493:pharmacokinetics*; D007408:Intestinal Absorption; D008239:Lysine / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D010592:Pharmaceutic Aids; D011205:Povidone; D012995:Solubility; D013607:Tablets; D013810:Therapeutic Equivalency
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010592:Pharmaceutic Aids; D013607:Tablets; D011205:Povidone; D008239:Lysine; C016106:solufenum; D007052:Ibuprofen