title: Lasers and light therapy for acne vulgaris.
abstract: Acne vulgaris remains an emotionally and debilitating dermatologic disease, and is conventionally treated with a variety of oral and topical therapies with a number of significant side effects. An evolving understanding of laser-tissue interactions involving Propionibacterium acnes-produced porphyrins, and the development of infrared nonablative lasers to target sebaceous glands, has lead to the development of an escalating number of laser, light and radiofrequency devices for acne. Used as monotherapy or in combination, these devices are showing promise as a method to clear acne in a convenient, non-invasive manner, though there remains a clear need for long-term data and randomized, blinded studies.
authors.affiliation: Department of Dermatology, University of Minnesota, USA.
authors.forename: Sachin S
authors.initials: SS
authors.lastname: Bhardwaj
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Rohrer
authors.forename: Kenneth
authors.initials: K
authors.lastname: Arndt
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy / Q000628:therapy*; D016908:Gram-Positive Bacterial Infections / Q000628:therapy*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D028022:Low-Level Light Therapy / Q000379:methods; D010778:Photochemotherapy / Q000379:methods; D010789:Phototherapy / Q000379:methods*; D011425:Propionibacterium acnes / Q000187:drug effects / Q000528:radiation effects*; D012627:Sebaceous Glands / Q000187:drug effects / Q000528:radiation effects*