title: MR imaging of CNS leiomyosarcoma in AIDS patients.
abstract: Leiomyosarcomas of the central nervous system are extremely rare; however they are becoming more prevalent in immunocompromised patients. The authors present MRI (Magnetic Resonance Imaging) of six cases of pathological proved leiomyosarcomas of the central nervous system in patients infected with human immunodeficiency virus. MR images of 4 cases of intraspinal leiomyosarcoma showed lobulated masses expanding multilevel of neural foramina with extradural and intradural extension, giving dumbbell appearance which mimic neurofibroma. Two cases of intracranial leiomyosarcoma revealed a mass at the left cavernous sinus involving prepontine cistern in one case and two lesions in the other case showing masses with dural based appearance at the region of the planum sphenoidale and the posterior aspect of the falx cerebri which mimiced a meningioma. The leiomyosarcoma should be included in the differential diagnosis of extra-axial CNS lesions in HIV-infected patients.
authors.affiliation: Department of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Sukalaya
authors.initials: S
authors.lastname: Lerdlum
authors.forename: Siriporn
authors.initials: S
authors.lastname: Lalitanantpong
authors.forename: Numphung
authors.initials: N
authors.lastname: Numkarunarunrote
authors.forename: Pattraporn
authors.initials: P
authors.lastname: Chaowanapanja
authors.forename: Chusana
authors.initials: C
authors.lastname: Suankratay
authors.forename: Shanop
authors.initials: S
authors.lastname: Shuangshoti
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000328:Adult; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000453:epidemiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000601:surgery