title: [Sudden death after 125I brachytherapy in prostate cancer patient: a case report].
abstract: A management of 125I isotope is defined by medical guideline from Ministry of Health, Labour and Welfare in Japan. According to this, when the patient died within one year after 125I interstitial permanent prostate brachytherapy, we have to do autopsy and collect all implanted isotopes as soon as possible. We report here, a 70-year-old man who underwent 125I interstitial permanent prostate brachytherapy for localized prostate cancer and one month after brachytherapy the patient died of acute cerebral hemorrhage, which was unrelated to the 125I brachytherapy. Autopsy was performed and collection of migrated isotopes was extremely difficult in technically. In addition, the cost of autopsy and distance from our hospital were also problems in this case. Treatment of prostate cancer with brachytherapy has increased in Japan, and we should establish management manual for sudden death case after 125I brachytherapy.
authors.affiliation: Departments of Urology, Kitasato University School of Medicine.
authors.forename: Masaki
authors.initials: M
authors.lastname: Kimura
authors.forename: Takefumi
authors.initials: T
authors.lastname: Satoh
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Fujita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okusa
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Iwamura
authors.forename: Masashi
authors.initials: M
authors.lastname: Kitano
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Ishiyama
authors.forename: Kazushige
authors.initials: K
authors.lastname: Hayakawa
authors.forename: Isao
authors.initials: I
authors.lastname: Okayasu
authors.forename: Shiro
authors.initials: S
authors.lastname: Baba
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D000368:Aged; D001344:Autopsy / Q000331:legislation & jurisprudence; D001918:Brachytherapy; D002543:Cerebral Hemorrhage / Q000209:etiology; D003645:Death, Sudden / Q000209:etiology*; D017408:Guidelines as Topic; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage
chemical_list: D007457:Iodine Radioisotopes