Transplantation of yeast-infected cardiac allografts: a report of 2 cases.
For the first time in the literature to date, we report 2 cases of transplantation of yeast-infected cardiac allografts. In both cases, endocardial vegetations were observed before graft implantation. Microbiologic samples grew yeasts: Rhodotorula glutinis was found close to the left atrial appendage in the first case and Candida parapsilosis was identified in a vegetation located at the base of the tricuspid valve in the second case. We discuss the possible routes of donor organ infection and management of these 2 unusual cases.
Gamma
Reto
R
Department of Cardiology, Swiss Cardiovascular Center Bern.
Carrel
Thierry
T
Schmidli
Jürg
J
Zimmerli
Stefan
S
Tanner
Hildegard
H
Hullin
Roger
R
Mohacsi
Paul J
PJ
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy; D015725:Fluconazole / Q000627:therapeutic use; D005500:Follow-Up Studies; D006085:Graft Survival; D006333:Heart Failure / Q000175:diagnosis / Q000601:surgery*; D016027:Heart Transplantation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D014019:Tissue Donors; D014184:Transplantation, Homologous; D019737:Transplants / Q000382:microbiology*; D016896:Treatment Outcome; D015003:Yeasts / Q000302:isolation & purification*
D000666:Amphotericin B; D015725:Fluconazole