[Beta-radiation as adjuvant treatment of in-stent restenosis in coronary vessels].
BACKGROUND
The purpose of this study was to describe our initial "real-world" experience with vascular b-radiation for in-stent restenosis using a simple angioplasty approach without stent implantation.


METHODS
Thirty-five consecutive patients with in-stent restenosis were treated with balloon angioplasty (n = 28), cutting balloon angioplasty (n = 3), or angioplasty plus stent implantation (only in case of significant dissection: n = 4), followed by catheter-based beta-radiation. Angiographic follow-up was performed after 6 to 10 months.


RESULTS
One patient experienced a left main stem occlusion immediately after beta-radiation, which necessitated an acute coronary bypass operation. No other complications related to the radiation procedure were observed. In-stent restenosis recurred in 6 of the 34 patients (18%).


CONCLUSIONS
Our results indicate that catheter-based radiation can be safely introduced at centres without previous experience with this treatment modality. Furthermore, the in-stent restenosis recurrence rates after catheter-based radiation which have been obtained in randomised trials can be reproduced in consecutive patients.
Maeng
Michael
M
Arhus Universitetshospital, Skejby Sygehus, Hjertemedicinsk Afdeling B, Arhus N. maeng@dadlnet.dk
Tanderup
Kari
K
Jessen
Karl Arne
KA
Krusell
Lars Romer
LR
Thuesen
Leif
L
D015906:Angioplasty, Balloon, Coronary; D001610:Beta Particles / Q000009:adverse effects / Q000627:therapeutic use*; D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000532:radiotherapy* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018714:Radiotherapy, Adjuvant; D015607:Stents / Q000009:adverse effects