title: [Gestational trophoblastic diseases: a retrospective study from 1997 to 2003].
abstract: BACKGROUND
  Trophoblastic diseases correspond to a very heterogeneous group of rare pathology in young women which fertility should be preserved.
  
  
  METHODS
  We conducted a retrospective study from 1997 to 2003, including all patients with molar pregnancy or trophoblatic tumor in our department of Obstetrics and Gynecology.
  
  
  RESULTS
  Fifteen patients were identified with 9 molar pregnancies, 5 trophoblastic tumors and 1 placental tumor of implantation site. The outcome was favorable for 14, and one patient died from her metastatic disease. For 4 patients we asked our university colleague for the optimal approach.
  
  
  CONCLUSIONS
  Management of molar pregnancies is well established. Persistent gestational disease is more rare and problematic with potential metastatic dissemination. Multidisciplinary care is often needed.
  
  
  CONCLUSIONS
  Persistent gestational disease should be managed in a highly specialized centre, as developed in the Lyon University Hospital.
authors.affiliation: Service de Gynécologie-Obstétrique, Centre Hospitalier, 46, avenue du General-de-Gaulle, 02200 Soissons. p.abboud@ch-soissons.fr
authors.forename: P
authors.initials: P
authors.lastname: Abboud
authors.forename: A
authors.initials: A
authors.lastname: Brohet
authors.forename: G
authors.initials: G
authors.lastname: Mansour
authors.forename: J
authors.initials: J
authors.lastname: Kraiem
authors.forename: L G
authors.initials: LG
authors.lastname: Houareau
authors.forename: M
authors.initials: M
authors.lastname: Lorenzato
authors.forename: P
authors.initials: P
authors.lastname: Birembaut
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D012189:Retrospective Studies