Identification of a novel human DRB1*13 allele by sequence-based DRB typing.
Herein, we report on a novel DRB1 allele (DRB1*1368) identified during sequence-based HLA-DRB typing. This new DRB1 allele is identical to DRB1*1301 at exon 2 except for a single-nucleotide substitution at codon 37, changing the amino acid Asn to Asp.
Caggiari
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Division of Experimental Oncology I, IRCCS, Centro di Riferimento Oncologico, Aviano (PN), Italy.
Simula
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MP
Marzotto
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A
Caragnano
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A
Luchetti
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M
Gabrielli
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A
De Re
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D000483:Alleles; D001483:Base Sequence; D005091:Exons; D005260:Female; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C506473:HLA-DRB1*13 antigen