[Genetic aspects of idiopatic inflammatory bowel disease].
Idiopatic bowel disease, Crohn' s disease and ulcerative colitis, are grave illneses of gastrointestinal tract. Mechanisms that lead to the development of inflammatory bowel disease are not well understood, but genetic play an important role. The main arguments gathered are ethnic/racial difference in disease frequency, positive family history, increased concordance rate in monozygotic twins relative to dizygotic and genes associated with Crohn's disease and ulcerative colitis. The enviromental factors play also an important role.
Pintér
Michal
M
Fakultní nemocnice v Hradci Králové, II. interní klinika. michalpinter@volny.cz
Kolesárová
Martina
M
D002874:Chromosome Mapping; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000208:ethnology / Q000235:genetics*