title: Post-transplant multiple myeloma in a pediatric renal transplant patient.
abstract: Post-transplant lymphoproliferative disease (PTLD) is a well-recognized complication of the intense immunosuppression required in solid organ and bone marrow transplant recipients. The clinical presentation is varied and can range from a benign infectious mononucleosis-like syndrome to malignant lymphoma. PTLD manifesting as multiple myeloma occurs rarely. We report the unique occurrence of Epstein-Barr virus (EBV)-associated post-transplant multiple myeloma in a 16-year-old male. In contrast to previously described cases of PTLD-myeloma type, this patient was very young, had a clear association with EBV, and an indolent clinical course.
authors.affiliation: Gwynne Hazen Cherry Memorial Laboratories, Division of Pediatric Hematology-Oncology, UCLA, Los Angeles, California, USA. wtcheng@labiomed.org
authors.forename: Wendy Y
authors.initials: WY
authors.lastname: Tcheng
authors.forename: Jonathan
authors.initials: J
authors.lastname: Said
authors.forename: Theodore
authors.initials: T
authors.lastname: Hall
authors.forename: Samhar
authors.initials: S
authors.lastname: Al-Akash
authors.forename: Marcio
authors.initials: M
authors.lastname: Malogolowkin
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Feig
mesh_terms: D000293:Adolescent; D016027:Heart Transplantation / Q000009:adverse effects; D004854:Herpesvirus 4, Human; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009101:Multiple Myeloma / Q000209:etiology* / Q000473:pathology / Q000821:virology