Inhibition effect of honey on the adherence of Salmonella to intestinal epithelial cells in vitro.
The aim of the study was to evaluate the antimicrobial effect and the ability of honey to prevent Salmonella interitidis adhering to intestinal epithelial cells in vitro. Antimicrobial activity was demonstrated. Bacterial adherence was assayed using S. interitidis cells that had been incubated first with honey and then with the intestinal epithelial cells. Results showed that honey at dilutions of up to 1:8 reduced bacterial adherence from 25.6+/-6.5 (control) to 6.7+/-3.3 bacteria per epithelial cell (P<0.001).
Alnaqdy
Adel
A
Department of Microbiology and Immunology, College of Medicine and Health Sciences, Sultan Qaboos University, P.O. 35, Al-Khod 123, Oman. aalwan@squ.edu.om
Al-Jabri
Ali
A
Al Mahrooqi
Zahra
Z
Nzeako
Basil
B
Nsanze
Herbert
H
D001422:Bacterial Adhesion / Q000187:drug effects*; D002478:Cells, Cultured; D015169:Colony Count, Microbial; D004847:Epithelial Cells / Q000382:microbiology*; D006722:Honey / Q000032:analysis; D006801:Humans; D012475:Salmonella / Q000254:growth & development / Q000502:physiology*; D012480:Salmonella Infections / Q000517:prevention & control*