Simple iron-amine catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing beta-hydrogens.
Mixtures of iron(III) chloride and appropriate amine ligands are active catalysts for the coupling of aryl Grignard reagents with primary and secondary alkyl halide substrates bearing beta-hydrogens, under mild and simple reaction conditions.
Bedford
Robin B
RB
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK. r.bedford@bristol.ac.uk
Bruce
Duncan W
DW
Frost
Robert M
RM
Hird
Michael
M