title: Emergence of metallo-beta-lactamase producing Pseudomonas aeruginosa in Pakistan.
abstract: We report a case of urinary tract infection due to metallo-beta-lactamase producing Pseudomonas aeruginosa resistant to carbapenems. This report signals an ominous development. Unless curbed by judicious use of antibiotics and early detection by screening tests, spread of this plasmid-mediated resistance can render the carbapenems ineffective.
authors.affiliation: Microbiology Department, Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: Tariq
authors.initials: T
authors.lastname: Butt
authors.forename: Muhammad
authors.initials: M
authors.lastname: Usman
authors.forename: Rifat Nadeem
authors.initials: RN
authors.lastname: Ahmad
authors.forename: Imran
authors.initials: I
authors.lastname: Saif
mesh_terms: D015780:Carbapenems / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000201:enzymology; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000201:enzymology*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D015780:Carbapenems; D001618:beta-Lactamases