Primary viscocanalostomy for juvenile open-angle glaucoma.
OBJECTIVE
To evaluate the efficacy and safety of primary viscocanalostomy for medically uncontrolled juvenile open-angle glaucoma (JOAG).


METHODS
Prospective, noncomparative, interventional case-series study.


METHODS
The study included 20 eyes of 20 consecutive patients with medically uncontrolled JOAG who were treated by viscocanalostomy at one institution. No surgical or laser procedure preceded viscocanalostomy. Surgical outcome was defined as an overall success by the following criteria: no visual field deterioration, no optic-neuropathy progression, postoperative intraocular pressure IOP < or =20 mm Hg, and IOP reduction > or =30% compared with baseline values with or without medication. When medications were not required, success was defined as complete. Cases that did not fulfill the aforementioned criteria and cases in which a surgical revision or further goniopuncture was performed were defined as a failure.


RESULTS
Gender distribution was similar. Fourteen eyes belonged to the white race; five eyes belonged to the black race, and one eye belonged to Arab ethnicity. Mean age (+/-SD) at operation was 33.77 +/- 6.16 years, with the mean preoperative IOP (+/-SD) at 22.9 +/- 4.77 mm Hg. Thirty-six months after operation, 16 cases (80%) were considered an overall success. In 11 cases (55%), success was complete. Four cases (20%) were considered failures. No serious complications were documented either during or after operation. In two cases (10%), we documented a spontaneously reabsorbed microhyphema. Trabeculo-Descemet-membrane microperforation occurred in two cases (10%). In two other cases (10%), Trabeculo-Descemet-membrane perforation occurred and was accompanied by iris prolapse that needed peripheral iridectomy.


CONCLUSIONS
Primary viscocanalostomy can efficiently and safely reduce intraocular pressure in cases of medically uncontrolled JOAG and provide a rational alternative to conventional surgical modalities.
Stangos
Alexandros N
AN
Department of Clinical Neurosciences, Division of Ophthalmology, University Hospitals of Geneva, 16 Plateau de Champel, 1206 Geneva, Switzerland.
Whatham
Andrew R
AR
Sunaric-Megevand
Gordana
G
D000293:Adolescent; D000328:Adult; D002648:Child; D003886:Descemet Membrane / Q000601:surgery*; D005260:Female; D018463:Filtering Surgery / Q000379:methods*; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D007431:Intraoperative Complications; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D012449:Safety; D014129:Trabecular Meshwork / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity; D014794:Visual Fields