title: Skin cancer as a contraindication to organ transplantation.
abstract: Skin cancer is the most common malignancy worldwide. When patients with a history of skin cancer present for organ transplantation, the vast majority are appropriate candidates. However, there is little guidance in the literature regarding the advisability of transplantation in patients with a history of high-risk skin cancer. With limited allograft resources, it is important to allocate organs to patients who will derive the most benefit. Adverse outcomes that may be associated with prior skin cancer include recurrence, metastasis, or death from relapse or decreased quality of life from numerous new primary skin cancers. This review provides prognostic guidance to transplant physicians evaluating transplantation candidates who have a history of skin cancer.
authors.affiliation: Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota, USA. Otley.clark@mayo.edu
authors.forename: Clark C
authors.initials: CC
authors.lastname: Otley
authors.forename: Ryutaro
authors.initials: R
authors.lastname: Hirose
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Salasche
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008545:Melanoma / Q000150:complications; D016377:Organ Transplantation / Q000379:methods*; D011379:Prognosis; D012306:Risk; D012878:Skin Neoplasms / Q000150:complications*; D009927:Tissue and Organ Procurement / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents