Analysis of key steps in the catalytic cross-coupling of alkyl electrophiles under Negishi-like conditions.
The use of tpy'(tpy'= 4,4',4''-tri-tert-butyl-terpyridine) as a ligand for nickel allows for the isolation of a Ni(I)-alkyl complex and a Ni(II)-alkyl halide complex, both of which can be used as mechanistic probes of key steps in alkyl cross-coupling reactions.
Jones
Gavin D
GD
Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
McFarland
Chris
C
Anderson
Thomas J
TJ
Vicic
David A
DA
D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D011725:Pyridines / Q000737:chemistry*
D003432:Cross-Linking Reagents; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D011725:Pyridines; D009532:Nickel