Hospital-based study of the economic burden associated with rotavirus diarrhea in Hong Kong.
BACKGROUND
Rotavirus infection is the most common cause of severe diarrhea in both developed and developing countries.


METHODS
To estimate the economic burden associated with rotavirus infection in Hong Kong, we combined data on the disease burden of rotavirus-associated hospital admissions with detailed cost data for a subsample of 471 children with diarrhea admitted to hospitals.


RESULTS
The annual total social cost and total direct medical cost for rotavirus-associated admissions were calculated as 4.3 US dollars and 4 million US dollars, respectively, by use of data collected during March 2001 to March 2003. The estimate of the direct medical costs was approximately 4-fold higher than a previous estimate; this difference largely reflects the greater disease burden identified through active disease surveillance conducted under the auspices of the Asian Rotavirus Surveillance Network. On average, families spent 120 US dollars when their child's admission was associated with rotavirus infection; this cost represents approximately 10% of the monthly salary of an unskilled or service worker.


CONCLUSIONS
These data emphasize the potential for a safe and effective rotavirus vaccine to reduce the economic burden associated with rotavirus disease.
Nelson
E Anthony S
EA
Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region. tony-nelson@cuhk.edu.hk
Tam
John S
JS
Yu
Ly-Mee
LM
Ng
Ying-Chu
YC
Bresee
Joseph S
JS
Poon
Kin-Hung
KH
Ng
Chi-Hang
CH
Ip
Kin-Sing
KS
Mast
T Christopher
TC
Chan
Paul K-S
PK
Parashar
Umesh D
UD
Fok
Tai-Fai
TF
Glass
Roger I
RI
D002675:Child, Preschool; D003365:Costs and Cost Analysis; D003967:Diarrhea / Q000191:economics* / Q000821:virology; D006723:Hong Kong; D006761:Hospitals; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012400:Rotavirus Infections / Q000191:economics*