title: [Acute nonalcoholic nonbiliary pancreatitis. Difficulties in diagnosis and possibility of nicotine toxicity].
abstract: BACKGROUND
  The possibility of nicotine toxicity, although rare, should be considered in cases of acute edematous pancreatitis.
  
  
  METHODS
  A 30-year-old woman was hospitalized to identify the cause of an initial episode of acute edematous pancreatitis. The observation of native anti-DNA and antiphospholipid antibodies suggested lupus pancreatitis and/or an antiphospholipid syndrome, both subsequently ruled out. The final diagnosis was nicotine poisoning induced by the combination of a nicotine patch and tobacco smoking.
  
  
  CONCLUSIONS
  Although a nicotine patch has never been reported in connection with an episode of acute pancreatitis before, this case suggests that such an event might be a rare complication of an overdose of nicotine.
authors.affiliation: Service de médecine interne et immunologie clinique, Hôpital Le Bocage, Bd de Lattre de Tassigny, 21000 Dijon. sabine.berthier@chu-dijon.fr
authors.forename: S
authors.initials: S
authors.lastname: Berthier
authors.forename: C
authors.initials: C
authors.lastname: Michiels
authors.forename: C
authors.initials: C
authors.lastname: Sgro
authors.forename: B
authors.initials: B
authors.lastname: Bonnotte
authors.forename: B
authors.initials: B
authors.lastname: Lorcerie
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D009538:Nicotine / Q000633:toxicity*; D018722:Nicotinic Agonists / Q000633:toxicity*; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis*
chemical_list: D018722:Nicotinic Agonists; D009538:Nicotine