Characterization of prolyl iminopeptidase-deficient Neisseria gonorrhoeae.
Prolyl iminopeptidase (PIP) is an enzyme produced by Neisseria gonorrhoeae, the detection of which is incorporated into several commercial test panels. In this report we describe two distinct mutations in the pip gene which account for the loss of PIP activity.
Blackmore
T
T
Laboratories, Wellington Hospital, Riddiford St., Private Bag 7902, Wellington South, New Zealand. timothy.blackmore@ccdhb.org.nz
Hererra
G
G
Shi
S
S
Bridgewater
P
P
Wheeler
L
L
Byrne
J
J
D000626:Aminopeptidases / Q000032:analysis / Q000235:genetics*; D016521:Electrophoresis, Gel, Pulsed-Field; D006069:Gonorrhea / Q000175:diagnosis*; D006801:Humans; D009154:Mutation; D009344:Neisseria gonorrhoeae / Q000201:enzymology* / Q000235:genetics
D000626:Aminopeptidases; C022450:prolyl aminopeptidase