title: Ischaemic colitis mimicking inflammatory bowel disease in a young adult receiving oral anticoagulation.
abstract: Ischaemic colitis (IC) is the most frequent form of gastrointestinal ischaemia. Discrepancy between non-specific symptoms and objective findings is a hallmark of IC. Thus delay of diagnosis is common due to its often subtle and unpredictable presentation. In particular, the clinical symptoms and signs of IC can overlap with those of inflammatory bowel disease. We present a case of a young man with known factor-V-Leiden mutation in whom IC developed during effective therapy with oral anticoagulants, presenting with symptoms and endoscopic findings suggestive of inflammatory bowel disease.
authors.affiliation: Department of Medicine B, Muenster University Hospital, Germany. willeke.peter@uni-muenster.de
authors.forename: Peter
authors.initials: P
authors.lastname: Willeke
authors.forename: Dirk
authors.initials: D
authors.lastname: Domagk
authors.forename: Martin
authors.initials: M
authors.lastname: Floer
authors.forename: Matthias
authors.initials: M
authors.lastname: Brüwer
authors.forename: Michael
authors.initials: M
authors.lastname: Kreuter
authors.forename: Markus
authors.initials: M
authors.lastname: Gaubitz
authors.forename: Wolfram
authors.initials: W
authors.lastname: Domschke
authors.forename: Torsten
authors.initials: T
authors.lastname: Kucharzik
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis / Q000209:etiology; D000284:Administration, Oral; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D025861:Blood Coagulation Disorders, Inherited / Q000175:diagnosis / Q000188:drug therapy*; D017091:Colitis, Ischemic / Q000175:diagnosis* / Q000628:therapy; D003113:Colonoscopy; D003937:Diagnosis, Differential; D005165:Factor V / Q000032:analysis* / Q000235:genetics; D005500:Follow-Up Studies; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index
chemical_list: D000925:Anticoagulants; D005165:Factor V