Expression of leptin receptor and suppressor of cytokine signaling-3 genes in adenohypophysis of normal-fed and fasted cows.
Expression of leptin receptor (LR) and suppressor of cytokine signaling (SOCS)-3 genes was investigated in normal-fed and fasted cows. Fasting did not affect LR mRNA, but increased SOCS-3 mRNA in the adenohypophysis, suggesting that heightened responsiveness of fasted cows to leptin is not dependent upon alterations in LR or SOCS-3 mRNA in the adenohypophysis.
Amstalden
Marcel
M
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati, Cincinnati, Ohio, USA.
Spencer
Thomas E
TE
Harms
Paul G
PG
Williams
Gary L
GL
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D005215:Fasting; D005260:Female; D005502:Food; D015870:Gene Expression; D010052:Ovariectomy; D010903:Pituitary Gland, Anterior / Q000737:chemistry*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000032:analysis; D011956:Receptors, Cell Surface / Q000235:genetics*; D054411:Receptors, Leptin; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins / Q000235:genetics*
C515448:LEPR protein, human; D012333:RNA, Messenger; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin; C106644:SOCS3 protein, human; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins