[The role of ceruloplasmin in neoplastic processes].
Ceruloplasmin (CP) is a copper containing oxidase of human plasma alpha 2-globulin fraction. The review summarizes literature data on biological role of CP under normal conditions and during development of malignant tumor. This protein may be involved both into antitumor deference and also into metastasizing process. Although CP has already been employed into intensive therapy of oncologic patients all mechanisms underlying its biological activity remain to be clarified.
Vavilova
T P
TP
Gusarova
Iu N
IuN
Koroleva
O V
OV
Medvedev
A E
AE
D000906:Antibodies / Q000097:blood; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D002570:Ceruloplasmin / Q000276:immunology / Q000502:physiology* / Q000627:therapeutic use*; D002614:Chelating Agents / Q000737:chemistry / Q000627:therapeutic use*; D003300:Copper / Q000737:chemistry; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology
D000906:Antibodies; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D002614:Chelating Agents; D003300:Copper; D002570:Ceruloplasmin