title: Directed ortho lithiation of N-alkylphenylaziridines.
abstract: The ortho lithiation-trapping sequence of phenylaziridines is described. This methodology, which counts on the ability of the aziridino group to act as a directed metalation group (DMG), provides an easy access to functionalized arylaziridines as well as to phthalans and phthalides. The importance of the aziridine N-substituent in this DoM reaction is stressed as well. [reaction: see text]
authors.affiliation: Dipartimento Farmaco-Chimico, University of Bari, Via E. Orabona 4, I-70126 Bari, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Capriati
authors.forename: Saverio
authors.initials: S
authors.lastname: Florio
authors.forename: Renzo
authors.initials: R
authors.lastname: Luisi
authors.forename: Biagia
authors.initials: B
authors.lastname: Musio