Short-course use of recombinant factor VIIa in a haemophilia patient with inhibitor undergoing cataract surgeries.
A 36 year-old patient with severe haemophilia A and high-titre inhibitor underwent cataract surgery under topical anaesthesia. Recombinant factor VIIa was used only three times, once before and twice following surgery. Tranexamic acid was given concomitantly. One month after the first successful procedure on the right eye, a second operation was performed on the left eye in the same manner. Both procedures were uneventful. Neither bleeding complications nor any other side effects occurred.
Pekçelen
Yüksel
Y
Division of Haematology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Turkey. ypekcelen@superonline.com
Yavuz
Akif S
AS
Namli
Sule
S
Gücükoglu
Ahmet
A
D000328:Adult; D019774:Blood Coagulation Factor Inhibitors / Q000097:blood*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002386:Cataract / Q000150:complications; D002387:Cataract Extraction; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D015942:Factor VIIa / Q000008:administration & dosage*; D006467:Hemophilia A / Q000097:blood / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male
D019774:Blood Coagulation Factor Inhibitors; D005169:Factor VIII; D015942:Factor VIIa