title: Ibuprofen extrudate, a novel, rapidly dissolving ibuprofen formulation: relative bioavailability compared to ibuprofen lysinate and regular ibuprofen, and food effect on all formulations.
authors.affiliation: Human Pharmacology Centre Ingelheim, Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Klueglich
authors.forename: Arne
authors.initials: A
authors.lastname: Ring
authors.forename: Stefan
authors.initials: S
authors.lastname: Scheuerer
authors.forename: Dirk
authors.initials: D
authors.lastname: Trommeshauser
authors.forename: Chris
authors.initials: C
authors.lastname: Schuijt
authors.forename: Bernd
authors.initials: B
authors.lastname: Liepold
authors.forename: Gunther
authors.initials: G
authors.lastname: Berndl
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000493:pharmacokinetics*; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D005260:Female; D018565:Food-Drug Interactions; D006801:Humans; D007052:Ibuprofen / Q000031:analogs & derivatives* / Q000737:chemistry / Q000493:pharmacokinetics*; D007408:Intestinal Absorption; D008239:Lysine / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D010592:Pharmaceutic Aids; D011205:Povidone; D012995:Solubility; D013607:Tablets; D013810:Therapeutic Equivalency
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010592:Pharmaceutic Aids; D013607:Tablets; D011205:Povidone; D008239:Lysine; C016106:solufenum; D007052:Ibuprofen