title: Documented cases of post-transfusion malaria occurring in England: a review in relation to current and proposed donor-selection guidelines.
abstract: OBJECTIVE
  Although uncommon, five cases of transfusion-transmitted malaria have been documented in England over the last 20 years. With the reappearance onto the market of high-quality malaria antibody assays, and by utilizing the results of analysis of these five cases, it has been possible to review the donor malaria-deferral guidelines.
  
  
  METHODS
  Details of the five cases of post-transfusion malaria were reviewed against the proposed new donor-deferral guidelines for malaria.
  
  
  RESULTS
  Three of the five cases of post-transfusion malaria were directly attributable to the deferral guidelines, allowing infectious donors to be bled.
  
  
  CONCLUSIONS
  The proposed new guidelines will prevent further cases of transmission from semi-immune individuals.
authors.affiliation: National Transfusion Microbiology Laboratories, National Blood Service, London, UK. alan.kitchen@nbs.nhs.uk
authors.forename: A D
authors.initials: AD
authors.lastname: Kitchen
authors.forename: J A J
authors.initials: JA
authors.lastname: Barbara
authors.forename: P E
authors.initials: PE
authors.lastname: Hewitt
mesh_terms: D000953:Antigens, Protozoan; D001771:Blood Banks; D001782:Blood Donors; D017848:Blood-Borne Pathogens; D018562:Disease Transmission, Infectious; D046148:Donor Selection; D004739:England; D005260:Female; D006801:Humans; D008288:Malaria / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D012306:Risk; D065227:Transfusion Reaction; D014195:Travel; D014330:Tropical Medicine
chemical_list: D000953:Antigens, Protozoan