title: Risk factors for mortality in children with candidemia.
abstract: We performed a retrospective cohort study of hospitalized children with positive blood cultures for Candida species. Independent risk factors for mortality by multivariable analysis were location in the pediatric intensive care unit at the time of infection (hazard ratio, 6.3; 95% confidence interval, 1.6-24.3) and the presence of an arterial catheter (hazard ratio, 2.4; 95% confidence interval, 1.1-5.8). Our findings help identify a group of pediatric patients that should be targeted for future interventions to prevent and treat candidemia.
authors.affiliation: Division of Infectious Diseases, The Children's Hospital of Philadelphia, PA 19104, USA. zaoutis@email.chop.edu
authors.forename: Theoklis E
authors.initials: TE
authors.lastname: Zaoutis
authors.forename: Susan E
authors.initials: SE
authors.lastname: Coffin
authors.forename: Jaclyn H
authors.initials: JH
authors.lastname: Chu
authors.forename: Kateri
authors.initials: K
authors.lastname: Heydon
authors.forename: Huaqing
authors.initials: H
authors.lastname: Zhao
authors.forename: H Mollie
authors.initials: HM
authors.lastname: Greves
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Walsh
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000401:mortality*; D002648:Child; D015331:Cohort Studies; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000401:mortality*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000935:Antifungal Agents