[Experimental study on antidiabetic effect of the total flavonoids in Leucaena seeds].
OBJECTIVE
To study the hypoglycemic effect of the total flavonoids in Leucaena seeds(TF).


METHODS
Experimental observation was performed by using various diabetic mice induced by alloxan, adrenalin, etc.


RESULTS
TF could significantly lower the blood glucose levels in Alloxan model mice, adrenalin model mice and hyperglycemic mice, while had no hypoglycemic effect on the normal mice.


CONCLUSIONS
The total flavonoids in Leucaena seeds has hypoglycemic effect in diabetic model mice.
Li
Xue-Jian
XJ
Pharmaceutical Factory of Guangxi Traditional Chinese Medical University, Nanning 530023, China.
Deng
Jia-Gang
JG
Qin
Zhen-Lin
ZL
Huang
Hai-Bin
HB
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D004837:Epinephrine; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D006943:Hyperglycemia / Q000097:blood / Q000139:chemically induced; D007004:Hypoglycemic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D012639:Seeds / Q000737:chemistry
D001786:Blood Glucose; D005419:Flavonoids; D007004:Hypoglycemic Agents; D004837:Epinephrine