title: [Relationship between fibrinogen content and the protracted inflammation of secretory otitis media].
abstract: OBJECTIVE
  To study the relationship between fibrinogen content and the protracted inflammation of secretory otitis media(SOM).
  
  
  METHODS
  The fibrinogen content of 98 patients with SOM was monitored with von-clauss technique at different stages.
  
  
  RESULTS
  Sixty-two patients of 98 patients with SOM experiences were not cured after the treatment by myringopuncture. The positive rate and the concentration of fibrinogen in the protracted group were 72.58% and (0.568 +/- 0.206) g/L respectively, higher than those in the cured group, 30. 56% and (0.350 +/- 0.124) g/L ( P < 0.05 in all ); fifty-two of sixty-two patients in protracted group were not cured after the second treatment of myringopuncture, the concentration of fibrinogen in the second protracted group were (1.241 +/- 0.146) g/L, higher than that in the first protracted group,(0.685 +/- 0.251) g/L (P < 0.01).
  
  
  CONCLUSIONS
  Fibrinogen content has significant relationship with the protracted inflammation of SOM. It might play an important role in the pathological course of middle ear adhesions.
authors.affiliation: Department of Otolaryngology, the First Affiliated Hospital, Sun-Yat-Sen University, Guangzhou, 510080, China. wuxuan2005@21cn.com
authors.forename: Xuan
authors.initials: X
authors.lastname: Wu
authors.forename: Xihui
authors.initials: X
authors.lastname: Chen
authors.forename: Bin
authors.initials: B
authors.lastname: Huang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000378:metabolism*
chemical_list: D005340:Fibrinogen