Enantioselective allylation of ketones catalyzed by chiral In(III)-PYBOX complexes.
In the presence of 20 mol% of chiral catalytic complex prepared from In(OTf)3 and chiral PYBOX, allyltributylstannane reacted with achiral ketones to afford the corresponding homoallylic alcohols in moderate to high enantioselectivities (54-95% ee), which constitutes the first example of enantioselective allylation of ketones catalyzed by the chiral In(III)-PYBOX complex.
Lu
Jun
J
Key Lab. of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering of Suzhou University, Suzhou 215006, China.
Hong
Mei-Ling
ML
Ji
Shun-Jun
SJ
Teo
Yong-Chua
YC
Loh
Teck-Peng
TP