title: Familial arachnoid cysts.
abstract: Arachnoid cysts are a relatively common incidental finding on neuroimaging studies of the brain. Although most cases are sporadic, there have been some reports of arachnoid cysts in several members of the same family. This report describes two additional families with three members affected in each one. Both families had members with arachnoid cysts in two consecutive generations. In one of the families, arachnoid cysts were associated with a deletion in the long arm of chromosome 16, an association not described previously. These descriptions suggest that in some cases arachnoid cysts may have a genetic basis.
authors.affiliation: Pediatric Neurology Section, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Arriola
authors.forename: Pedro
authors.initials: P
authors.lastname: de Castro
authors.forename: Alfonso
authors.initials: A
authors.lastname: Verdú
mesh_terms: D016080:Arachnoid Cysts / Q000235:genetics* / Q000473:pathology*; D002675:Child, Preschool; D002872:Chromosome Deletion; D002885:Chromosomes, Human, Pair 16; D005192:Family Health; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male