The problems of indeterminate HIV results in blood transfusion services in Nigeria.
Five hundred sera samples were collected from individuals whose age range was 16-40 years, analysed using Murex 1 and 2 and Capillus HIV kit (Cambridge Biotechnology, Cambridge, UK), and confirmed with Western Blot technique (Biorad). Of these, 186 (37.2%) were repeatedly reactive, 90 (48.4%) were confirmed positive, 55 (29.6%) indeterminate (20 [10.7%] from blood donors) and 44 (22.0%) were negative. The data reveal a significant correlation between indeterminate results and confirmed positive sera (P < 0.05). This demonstrates the high incidence of indeterminate HIV results encountered in blood transfusion services.
Elemuwa
C O
CO
Federal Vaccine Production Laboratories, Federal Ministry of Health, Yaba, Lagos, Nigeria.
Bassey
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BE
Olaleye
D O
DO
D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D019937:Diagnostic Techniques and Procedures; D015658:HIV Infections / Q000175:diagnosis*; D006679:HIV Seropositivity / Q000175:diagnosis*; D006801:Humans; D008403:Mass Screening; D009549:Nigeria