title: Efficacy of MR mammography (MRM) in providing preoperative locoregional information on breast cancer: correlation between MRM and histological findings.
abstract: OBJECTIVE
  To assess the efficacy of MRM in providing preoperative locoregional information on patients with breast cancer.
  
  
  METHODS
  MRI was performed on 62 female breast cancer patients. A 1.5T MR-system was used to acquire fat-suppressed T(1)WI, T(2)WI and dynamic-contrast-enhanced images with an SPGR pulse sequence. The extent of the cancer measured with MRM was confirmed histologically in all patients.
  
  
  RESULTS
  The size obtained from MRM correlated well with the size obtained histologically, including intraductal spread of cancer (R: 0.853). As for shape, the round/oval type evident from MRM correlated more accurately (R: 0.934) than the ill-defined type associated with a linear and/or clumped enhanced area (R: 0.744). The difference between the size obtained from MRM and the size obtained histologically, including IDS, was less than 15 mm in the majority of patients (93.5%).
  
  
  CONCLUSIONS
  MRM accurately reveals the extent of cancer, including IDS, and is effective at providing preoperative locoregional information for breast-conserving therapy for breast cancer.
authors.affiliation: Diagnostic Radiology, Diagnostic Oncology Divisions, National Cancer Center Hospital East 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan. ykuroki@tcc.pref.tochigi.jp
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kuroki
authors.forename: Shigeru
authors.initials: S
authors.lastname: Nawano
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hasebe
authors.forename: Shigeru
authors.initials: S
authors.lastname: Imoto
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Nasu
authors.forename: Koji
authors.initials: K
authors.lastname: Murakami
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Satake
authors.forename: Ryuzo
authors.initials: R
authors.lastname: Sekiguchi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D003287:Contrast Media; D005260:Female; D006801:Humans; D016014:Linear Models; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008327:Mammography; D015411:Mastectomy, Modified Radical; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging
chemical_list: D003287:Contrast Media