title: [Conformal radiation therapy with or without intensity modulation in the treatment of localized prostate cancer].
abstract: Conformal radiation therapy has now to be considered as a standard treatment of localized prostatic adenocarcinomas. Using conformational methods and intensity modulated radiation therapy requires a rigorous approach for their implementation in routine, focused on the reproducibility of the treatment, target volume definitions, dosimetry, quality control, setup positioning. In order to offer to the largest number of patients high-dose treatment, the clinicians must integrate as prognostic factors accurate definition of microscopic extension as well as the tolerance threshold of critical organs. High-dose delivery is expected to be most efficient in intermediary risks and locally advanced diseases. Intensity modulated radiation therapy is specifically dedicated to dose escalation. Perfect knowledge of classical constraints of conformal radiation therapy is required. Using such an approach in routine needs a learning curve including the physicists and a specific quality assurance program.
authors.affiliation: Département de radiothérapie, centre Georges-François-Leclerc, 1, rue du Professeur-Marion, 21079 Dijon cedex, France. mcperrin@dijon.fnclcc.fr
authors.forename: P
authors.initials: P
authors.lastname: Maingon
authors.forename: M
authors.initials: M
authors.lastname: Bolla
authors.forename: G
authors.initials: G
authors.lastname: Truc
authors.forename: M
authors.initials: M
authors.lastname: Bosset
authors.forename: K
authors.initials: K
authors.lastname: Peignaux
authors.forename: A
authors.initials: A
authors.lastname: Ammor
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D020266:Radiotherapy, Conformal / Q000379:methods*