Nonspecific granulomatous prostatitis with calculous ductal ectasia and extensive Paneth cell-like epithelial metaplasia. Case report.
We present a case of nonspecific granulomatous prostatitis in combination with calculous ductal ectasia and extensive epithelial Paneth cell-like metaplasia in a TURP-specimen. Our report highlights the importance of calculous ductal obstruction and stasis of secretions in the etiopathogenesis of this type of prostatitis. The observed extensive Paneth cell-like metaplastic change in adjacent epithelial cells most likely represents a phenotypic adaptive mechanism directed against foreign antigens and nondegradable lipids in the stagnant intraluminal debris.
Dikov
Dorian
D
Service d'Anatomie Pathologique, Centre Hospitalier de Lagny-Marne-La-Vallée, Lagny-sur-Marne, France. ddikov@ch-lagny77.fr
Vassilev
Ivan
I
Dimitrakov
Jordan
J
D000368:Aged; D002137:Calculi / Q000473:pathology; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D008679:Metaplasia; D019879:Paneth Cells / Q000473:pathology; D011472:Prostatitis / Q000473:pathology*