Radiation protection of DNA and membrane in vitro by extract of Hemidesmus indicus.
Radioprotective effect of H. indicus root extract on lipid peroxidation in rat liver microsomes and plasmid DNA was examined. Hemidesmus indicus (HI) root extract was found to protect microsomal membranes as evident from reduction in lipid peroxidation values. The extract could also protect DNA from radiation induced strand breaks.
Shetty
T K
TK
Radiation Biology Division, Bhabha Atomic Research Centre, Mumbai, India.
Satav
J G
JG
Nair
C K K
CK
D000818:Animals; D004249:DNA Damage / Q000187:drug effects* / Q000528:radiation effects; D005720:Gamma Rays; D031102:Hemidesmus; D007425:Intracellular Membranes / Q000187:drug effects / Q000528:radiation effects; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000528:radiation effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D010957:Plasmids / Q000187:drug effects / Q000528:radiation effects; D011837:Radiation-Protective Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar
D010936:Plant Extracts; D011837:Radiation-Protective Agents