Is it time to prescribe statins to patients with calcified aortic stenosis?
Aortic stenosis (AS) is a common disease especially in the older population. It is associated with high mortality and morbidity. Recent data suggest that coronary artery disease and AS share common risk factors. Retrospective studies suggest that statins might slow the progression of AS but there are no randomized clinical trial data available. It would seem that statins can be considered for medical treatment of AS; however, this needs to be investigated in future randomized clinical trials.
Rashidi
Arash
A
Fairview Hospital, Cleveland Clinic Health System, Cleveland, Ohio 44111, USA. arashrashidi@sbcglobal.net
Adler
Dale S
DS
Casscells
Ward
W
Madjid
Mohammad
M
D001018:Aortic Diseases / Q000150:complications / Q000188:drug therapy; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000188:drug therapy*; D002114:Calcinosis / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D012307:Risk Factors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors