title: Multi-focal gliosarcoma: a case report and review of the literature.
abstract: Gliosarcoma (GS) is an uncommon malignant brain tumor with biphasic tissue pattern consisted of both glial and sarcomatous components. It usually occurs in adult population of middle age. We report a rare case of multi-focal GS that was initially interpreted as metastases of extra-cranial tumor. The histological examination revealed the biphasic pattern of a GS. The patient was treated with postoperative external radiation therapy and had poor prognosis. To our knowledge this is the second published case of GS with multi-focal presentation. In this study we also review the literature on clinicopathological aspects of GS.
authors.affiliation: Department of Radiation Therapy, University Hospital of Ioannina, University of Ioannina, Greece. epakos@yahoo.gr
authors.forename: E E
authors.initials: EE
authors.lastname: Pakos
authors.forename: A C
authors.initials: AC
authors.lastname: Goussia
authors.forename: V P
authors.initials: VP
authors.lastname: Zina
authors.forename: E J
authors.initials: EJ
authors.lastname: Pitouli
authors.forename: P G
authors.initials: PG
authors.lastname: Tsekeris
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology* / Q000628:therapy; D017809:Fatal Outcome; D018316:Gliosarcoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged