title: [Neurological late sequelae in twins born after in vitro fertilisation--secondary publication. A national cohort study].
abstract: Currently 4% of the Danish national birth cohort is born after in vitro fertilisation techniques and almost 40% of these children are twins. In this register-based national cohort study, twins from assisted conception (n = 3393) had a similar risk of neurological sequelae and cerebral palsy as their naturally conceived peers (n = 10.239) and assisted conceived singletons (n = 5130). Further children born after intracytoplasmic sperm injection (ICSI) had the same risk of neurological sequelae as children born after conventional IVF.
authors.affiliation: H:S Rigshospitalet, Fertilitetsklinikken og Neonatalklinikken, Københavns Universitet, Institut for Folkesundhedsvidenskab, ogSundhedsstyrelsen, Afdeling for Sundhedsstatistik. apinborg@rh.hosp.dk
authors.forename: Anja
authors.initials: A
authors.lastname: Pinborg
authors.forename: Anne
authors.initials: A
authors.lastname: Loft
authors.forename: Lone
authors.initials: L
authors.lastname: Schmidt
authors.forename: Gorm
authors.initials: G
authors.lastname: Greisen
authors.forename: Steen
authors.initials: S
authors.lastname: Rasmussen
authors.forename: Anders Nyboe
authors.initials: AN
authors.lastname: Andersen
mesh_terms: D000328:Adult; D002547:Cerebral Palsy / Q000453:epidemiology / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004200:Diseases in Twins / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008607:Intellectual Disability / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008423:Maternal Age; D009422:Nervous System Diseases / Q000453:epidemiology / Q000209:etiology*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011596:Psychomotor Disorders / Q000453:epidemiology / Q000209:etiology; D012042:Registries; D012307:Risk Factors; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects*; D014427:Twins