New signaling routes for an old drug: lipoxin A4 might mediate heme oxygenase-1 induction by aspirin. Focus on "Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells".
Schröder
Henning
H
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D042783:Endothelial Cells / Q000187:drug effects* / Q000378:metabolism; D006419:Heme Oxygenase (Decyclizing) / Q000378:metabolism*; D051547:Heme Oxygenase-1; D006801:Humans; D044045:Lipoxins / Q000378:metabolism / Q000494:pharmacology*; D008565:Membrane Proteins; D015398:Signal Transduction / Q000187:drug effects
C447621:16-(4-fluorophenoxy)lipoxin A4; D016861:Cyclooxygenase Inhibitors; D044045:Lipoxins; D008565:Membrane Proteins; C040527:lipoxin A4; C496541:HMOX1 protein, human; D006419:Heme Oxygenase (Decyclizing); D051547:Heme Oxygenase-1; D001241:Aspirin