Adult onset tubulointerstitial nephritis and uveitis syndrome.
A Turkish woman aged 44 years who presented with a 1 month history of abdominal pain, fatigue and weight loss of 10 kg was diagnosed as having acute tubulointerstitial nephritis. Opthalmological evaluation revealed unilateral uveitis and contralateral chorioretinal scarring. X-ray films of the pelvis revealed unilateral sacroileitis. An elevated erythrocyte sedimentation rate, C-reactive protein, tubular proteinuria and renal glucosuria returned to normal 2 weeks after treatment was started. It is important to be aware of tubulointerstitial nephritis and uveitis syndrome in order to achieve a quick diagnosis in patients with renal impairment and tubular dysfunction with minor symptoms so that appropriate management can be started early.
Kaynar
Kubra
K
Department of Nephrology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey. kkaynar@yahoo.com
Ersoz
Safak
S
Akyol
Nurettin
N
Ersoz
Onder
O
Unlu
Ozge
O
Ozbay
Tulin
T
Ulusoy
Sukru
S
D000328:Adult; D000483:Alleles; D005260:Female; D006684:HLA-DR Antigens / Q000235:genetics; D059811:HLA-DRB1 Chains; D006801:Humans; D009395:Nephritis, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D013577:Syndrome; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis / Q000235:genetics
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains