title: A convenient preparation of xanthene dyes.
abstract: A facile synthetic route utilizing readily available reagents affords a series of regioisomerically pure xanthene dye derivatives. Advantages include relatively mild conditions and good to excellent yields. Nonpolar, highly crystalline intermediates are isolable by standard chromatographic techniques. The intermediates are in the requisite xanthene oxidation state, thus avoiding the need for relatively inefficient oxidation chemistry and/or harsh conditions. During the course of this work, a new boron-mediated 1,2-aryl migration reaction was discovered.
authors.affiliation: Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, USA.
authors.forename: Youjun
authors.initials: Y
authors.lastname: Yang
authors.forename: Jorge O
authors.initials: JO
authors.lastname: Escobedo
authors.forename: Alexander
authors.initials: A
authors.lastname: Wong
authors.forename: Corin M
authors.initials: CM
authors.lastname: Schowalter
authors.forename: Michael C
authors.initials: MC
authors.lastname: Touchy
authors.forename: Lijuan
authors.initials: L
authors.lastname: Jiao
authors.forename: William E
authors.initials: WE
authors.lastname: Crowe
authors.forename: Frank R
authors.initials: FR
authors.lastname: Fronczek
authors.forename: Robert M
authors.initials: RM
authors.lastname: Strongin
mesh_terms: D004396:Coloring Agents / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014966:Xanthenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004396:Coloring Agents; D014966:Xanthenes