[Appropriate dose of isobaric bupivacaine with fentanyl in spinal anesthesia for cesarean section].
BACKGROUND
Spinal anesthesia combined with fentanyl is commonly used for cesarean section. We studied the appropriate dose of isobaric bupivacaine for spinal anesthesia when combined with a fixed dose of 20 microg fentanyl.


METHODS
Forty-seven women scheduled for cesarean section were allocated into four-groups according to the dose of 0.5% isobaric bupivacaine with 20 microg fentanyl; 1.0 ml (n=5), 1.5 ml (n=11), 2.0 ml (n=11), and 2.5 ml (n=20).


RESULTS
The requirement of epidural anesthesia for pain relief or muscle relaxant was less in the 2.0 ml and 2.5 ml groups than the other groups. However, dyspnea due to high spinal anesthesia developed in 3 subjects out of 20 in the 2.5 ml group.


CONCLUSIONS
Two ml of 0.5% isobaric bupivacaine was the most appropriate dose for cesarean section, when combined with 20 microg of fentanyl.
Kimoto
Michiyo
M
Department of Anesthesiology, Kansai Medical University Hospital, Moriguchi 570-8506.
Murao
Kouhei
K
Shirane
Atsuko
A
Sakamoto
Sachiyo
S
Yamada
Makiko
M
Nakao
Shin-ichi
S
Shingu
Koh
K
D000328:Adult; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical / Q000009:adverse effects; D000775:Anesthesia, Spinal / Q000009:adverse effects; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D002585:Cesarean Section; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D011247:Pregnancy
D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D005283:Fentanyl; D002045:Bupivacaine