title: [Study on extracting oil of radix Angelica sinensis with supercritical CO2].
abstract: OBJECTIVE
  To study the extraction of angelica oil by SFE-CO2 (CO2 Supercritical Fluid Extraction).
  
  
  METHODS
  Investigating the influence of the granule size of medical material, extraction temperature, extraction pressure, extraction time, releasing and separating condition on the extraction of angelica oil by the orthogonal design and other methods.
  
  
  RESULTS
  The optimum extraction is as follows: the granule size of medical material, 40 mu; extraction temperature, 40 degrees C; extraction pressure, 25Mpa; extraction time, 2 hours; flow of CO2, 20 L/h; pressure of separation pot I, 8Mpa; temperature of separation pot I, 50 degrees C; pressure of separation pot II, 6Mpa; temperature of separation pot II, 50 degrees C.
  
  
  CONCLUSIONS
  The optimum extraction has high extraction ratio of angelica oil. The optimum extraction is reasonable and practicable.
authors.affiliation: Pharmaceutical Aademy, Hubei College of TCM, Wuhan.
authors.forename: Shiming
authors.initials: S
authors.lastname: Nie
authors.forename: Guizhi
authors.initials: G
authors.lastname: Zhang
authors.forename: Pengtao
authors.initials: P
authors.lastname: Zhang
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry*; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods; D009822:Oils, Volatile / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors
chemical_list: D009822:Oils, Volatile; D002245:Carbon Dioxide