title: Dependence of Mini-Nutritional Assessment scores with age and some hematological variables in elderly institutionalized patients.
abstract: BACKGROUND
  Nutritional imbalance is a serious problem in developing countries, especially for the older population, which makes simple and rapid instruments for nutritional evaluation very necessary in order to have a detailed picture of the undernutrition epidemiology in those places.
  
  
  OBJECTIVE
  This work aimed to evaluate the nutritional status of elderly institutionalized patients by use of the Mini-Nutritional Assessment (MNA) test and compare the MNA scores with some hematological variables.
  
  
  METHODS
  We performed a cross-sectional study in elderly institutionalized patients (153) of all nursing homes in the Brazilian city of Uberlândia, using the MNA questionnaire and quantitative analysis of erythrocytes, hematocrit, hemoglobin, serum iron and transferrin. The subjects were classified by gender, nutritional state and age range. The nutritional categories were compared by analysis of variance and the dependence between the considered variables was tested with the Spearman correlation analysis.
  
  
  RESULTS
  60% of the subjects were female. The average age was 74.6 +/- 9.5 and 78.5 +/- 9.5 years for male and female individuals, respectively. 18.3% of the patients presented undernutrition, 45.7% presented risk of undernutrition, and 36.0% were well nourished. These three nutritional categories showed statistically significant differences among the MNA scores, age and all the hematological parameters, for the sum of both genders, but not for the age, iron and transferrin values of the male individuals and hematocrit and hemoglobin values of the female patients. Significant differences between genders were not observed only for the MNA and transferrin values. MNA values presented positive correlations with erythrocytes, hematocrit, hemoglobin, and serum iron levels, and also a negative correlation with age, which was attributed to a worsening of the nutritional state with age.
  
  
  CONCLUSIONS
  Based on the MNA, 64% of the elderly institutionalized patients of Uberlândia presented risk of undernutrition and undernutrition, and their nutritional state is aggravating with the age increase, which is consistent with the age-dependent decrease observed in some hematological variables. Since the low MNA scores were not necessarily associated to subnormal mean values of the hematological variables, we can conclude that the low MNA values are predicting situations that still did not manifest pathologically in those variables.
authors.affiliation: Faculty of Medicine and Institute of Genetics and Biochemistry, Federal University of Uberlândia, Uberlândia, Brazil.
authors.forename: Carlos Henrique
authors.initials: CH
authors.lastname: Alves de Rezende
authors.forename: Thúlio
authors.initials: T
authors.lastname: Marquez Cunha
authors.forename: Valter
authors.initials: V
authors.lastname: Alvarenga Júnior
authors.forename: Nilson
authors.initials: N
authors.lastname: Penha-Silva
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D003430:Cross-Sectional Studies; D004906:Erythrocyte Count; D005260:Female; D015577:Geriatric Assessment / Q000379:methods / Q000706:statistics & numerical data; D006400:Hematocrit; D006454:Hemoglobins; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data; D007501:Iron / Q000097:blood; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D009748:Nutrition Disorders / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology*; D012307:Risk Factors; D014168:Transferrin / Q000378:metabolism
chemical_list: D006454:Hemoglobins; D014168:Transferrin; D007501:Iron