title: Isolated pineal region metastasis of small cell lung cancer.
abstract: The pineal region is an unusual site for brain metastasis and most metastatic pineal lesions are asymptomatic. Rarely the symptoms of metastatic involvement of the pineal gland precede those of the primary tumor or other metastatic sites. An 83 year-old man presented with gait disturbance and limitation of upward gaze. Brain MRI showed homogeneous enhancement of a solitary mass in the pineal region with obstructive hydrocephalus. A stereotactic biopsy was performed, and small cell carcinoma was diagnosed. A systemic investigation for the primary lesion subsequently revealed small cell carcinoma of the lung. The patient was referred for radiotherapy and chemotherapy. Although rare, metastatic tumor should be considered in the differential diagnosis of pineal region tumors, particularly in elderly patients.
authors.affiliation: Department of Neurosurgery, Pundang CHA Hospital, Pochon CHA University, Sungnam, South Korea. jyahn@cha.ac.kr
authors.forename: Jung Yong
authors.initials: JY
authors.lastname: Ahn
authors.forename: Young Sun
authors.initials: YS
authors.lastname: Chung
authors.forename: Seong Oh
authors.initials: SO
authors.lastname: Kwon
authors.forename: Ryoong
authors.initials: R
authors.lastname: Huh
authors.forename: Sang Sup
authors.initials: SS
authors.lastname: Chung
mesh_terms: D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000556:secondary*; D018288:Carcinoma, Small Cell / Q000473:pathology*; D004358:Drug Therapy / Q000379:methods; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010871:Pinealoma / Q000556:secondary*; D011878:Radiotherapy / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods