Prevalence of ultrasonography proved polycystic ovaries in North Indian women with type 2 diabetes mellitus.
BACKGROUND
Polycystic ovaries (PCO) and their clinical expression (the polycystic ovary syndrome [PCOS]) as well as type 2 diabetes mellitus (T2DM) are common medical conditions linked through insulin resistance. We studied the prevalence of PCO and PCOS in women with diet and/or oral hypoglycemic treated T2DM and non-diabetic control women.


METHODS
Prospective study.


METHODS
One hundred and five reproductive age group women with diet and /or oral hypoglycemic treated T2DM were the subjects of the study. Sixty age-matched non-diabetic women served as controls. Transabdominal ultrasonographic assessment of the ovaries was used to diagnose PCO. Clinical, biochemical and hormonal parameters were also noted.


RESULTS
Ultrasonographic prevalence of PCO was higher in women with diabetes than in non-diabetic subjects (61.0% vs. 36.7%, P < 0.003) whereas that of PCOS was 37.1% in diabetic subjects and 25% in non-diabetic controls (P > 0.1). Diabetic women with PCO had diabetes of significantly longer duration than those without PCO (4.19+/-2.0 versus 2.9+/-1.6 yrs; p < 0.05). Among both diabetic and non-diabetic women, those with PCO had significantly higher plasma LH, LH/FSH ratio, total testosterone and androstenedione levels.


CONCLUSIONS
This study demonstrates a higher prevalence of PCO in women with T2DM as compared to non-diabetic subjects.
Zargar
Abdul H
AH
Department of Endocrinology, Sheri-Kashmir Institute of Medical Sciences Srinagar, J&K, India. abdulhamidz@vsnl.com
Gupta
Vipin K
VK
Wani
Arshad I
AI
Masoodi
Shariq R
SR
Bashir
Mir I
MI
Laway
Bashir A
BA
Ganie
Mohammad A
MA
Salahuddin
Mohammad
M
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015995:Prevalence; D011446:Prospective Studies; D014463:Ultrasonography
D001786:Blood Glucose; D008078:Cholesterol, LDL; D002784:Cholesterol