title: [The role of ceruloplasmin in neoplastic processes].
abstract: Ceruloplasmin (CP) is a copper containing oxidase of human plasma alpha 2-globulin fraction. The review summarizes literature data on biological role of CP under normal conditions and during development of malignant tumor. This protein may be involved both into antitumor deference and also into metastasizing process. Although CP has already been employed into intensive therapy of oncologic patients all mechanisms underlying its biological activity remain to be clarified.
authors.forename: T P
authors.initials: TP
authors.lastname: Vavilova
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Gusarova
authors.forename: O V
authors.initials: OV
authors.lastname: Koroleva
authors.forename: A E
authors.initials: AE
authors.lastname: Medvedev
mesh_terms: D000906:Antibodies / Q000097:blood; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D002570:Ceruloplasmin / Q000276:immunology / Q000502:physiology* / Q000627:therapeutic use*; D002614:Chelating Agents / Q000737:chemistry / Q000627:therapeutic use*; D003300:Copper / Q000737:chemistry; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology
chemical_list: D000906:Antibodies; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D002614:Chelating Agents; D003300:Copper; D002570:Ceruloplasmin