Relation of anemia at discharge to survival after acute coronary syndromes.
Two-year survival rate was assessed among 1,038 patients who had acute coronary syndromes that were classified by discharge hematocrit values as normal (>39%, n = 360, 34.7%), mildly anemic (33.1% to 39%, n = 430, 41.4%), or moderately/severely anemic (< or = 33%, n = 248, 23.9%). Worsening anemia was associated with a decreased 2-year survival rate (normal 95.8%, mild anemia 91.2%, moderate/severe anemia 81.5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia.
Vaglio
Joseph
J
Mid America Heart Institute of Saint Luke's Hospital, Missouri, USA.
Safley
David M
DM
Rahman
Mohamed
M
Kosiborod
Mikhail
M
Jones
Philip
P
Thompson
Randall
R
Krumholz
Harlan M
HM
Spertus
John A
JA
D000368:Aged; D000740:Anemia / Q000503:physiopathology*; D000789:Angina, Unstable / Q000097:blood / Q000401:mortality* / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D002423:Cause of Death / Q000639:trends; D017023:Coronary Angiography; D018450:Disease Progression; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006400:Hematocrit / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D009203:Myocardial Infarction / Q000097:blood / Q000401:mortality* / Q000503:physiopathology; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors; D014336:Troponin / Q000097:blood
D015415:Biomarkers; D014336:Troponin