title: Pseudomonas aeruginosa rhamnolipids disperse Bordetella bronchiseptica biofilms.
abstract: We have previously reported that the respiratory pathogen Bordetella bronchiseptica can form biofilms in vitro. In this report, we demonstrate the disruption of B. bronchiseptica biofilms by rhamnolipids secreted from Pseudomonas aeruginosa. This suggests that biosurfactants such as rhamnolipids may be utilized as antimicrobial agents for removing Bordetella biofilms.
authors.affiliation: Department of Microbiology, University of Pennsylvania School of Medicine, 201C Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6084, USA.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Irie
authors.forename: George A
authors.initials: GA
authors.lastname: O'toole
authors.forename: Ming H
authors.initials: MH
authors.lastname: Yuk
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D016950:Bordetella bronchiseptica / Q000187:drug effects* / Q000254:growth & development; D015169:Colony Count, Microbial; D006017:Glycolipids / Q000302:isolation & purification / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000737:chemistry*; D013194:Staining and Labeling; D013501:Surface-Active Agents / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D006017:Glycolipids; D013501:Surface-Active Agents; C418382:rhamnolipid