High-throughput LC/MS methodology for a(1-->3)Gal determination of recombinant monoclonal antibodies: a case study.
Huang
Lihua
L
Bioproduct Research and Development, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
Mitchell
Charles E
CE
D000911:Antibodies, Monoclonal / Q000737:chemistry* / Q000302:isolation & purification; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid / Q000379:methods*; D005690:Galactose / Q000032:analysis* / Q000737:chemistry*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D011994:Recombinant Proteins / Q000737:chemistry* / Q000302:isolation & purification
D000911:Antibodies, Monoclonal; D011994:Recombinant Proteins; D005690:Galactose