title: First clinical implant of the VentrAssist left ventricular assist system as destination therapy for end-stage heart failure.
abstract: The VentrAssist device left ventricular assist system, designed for permanent implantation, is a novel centrifugal pump with a hydrodynamically suspended rotor. The first human implant was into a 72-year-old man with New York Heart Association (NYHA) class IV heart failure due to idiopathic dilated cardiomyopathy. The implant and recovery were uneventful, and the patient survives at 17 months, is NYHA class II, and lives at home. This device shows promise in end-stage heart failure for permanent implantation and bridge to transplantation.
authors.affiliation: Department of Cardiothoracic Surgery, Alfred Hospital, Prahran, Victoria, Australia.
authors.forename: Donald S
authors.initials: DS
authors.lastname: Esmore
authors.forename: David
authors.initials: D
authors.lastname: Kaye
authors.forename: Robert
authors.initials: R
authors.lastname: Salamonsen
authors.forename: Mark
authors.initials: M
authors.lastname: Buckland
authors.forename: Michael
authors.initials: M
authors.lastname: Rowland
authors.forename: Justin
authors.initials: J
authors.lastname: Negri
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Rowley
authors.forename: John
authors.initials: J
authors.lastname: Woodard
authors.forename: John R
authors.initials: JR
authors.lastname: Begg
authors.forename: Peter
authors.initials: P
authors.lastname: Ayre
authors.forename: Franklin L
authors.initials: FL
authors.lastname: Rosenfeldt
mesh_terms: D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000601:surgery*; D004867:Equipment Design; D004869:Equipment Safety; D005500:Follow-Up Studies; D006333:Heart Failure / Q000175:diagnosis / Q000601:surgery*; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000601:surgery*