title: Chloroplast outer membrane protein targeting and insertion.
abstract: Proteins in the chloroplast outer envelope membrane are nuclear encoded and post-translationally targeted to the chloroplast. The targeting and membrane insertion of these proteins is not well understood. Although early work suggested otherwise, the best-studied outer membrane proteins (OMPs) use both proteins within the chloroplast and NTPs for insertion. There have been conflicting reports in the field regarding protein targeting and insertion, which have probably arisen because of differences in experimental methodology and different interpretations of reduction (versus abolition) of integration. This review summarizes what is known to date about the mechanism of chloroplast OMP targeting.
authors.affiliation: Section of Plant Biology, University of California - Davis, Davis, CA 95616, USA.
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Hofmann
authors.forename: Steven M
authors.initials: SM
authors.lastname: Theg
mesh_terms: D000595:Amino Acid Sequence; D002736:Chloroplasts / Q000378:metabolism*; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism*; D008969:Molecular Sequence Data; D021382:Protein Sorting Signals; D017386:Sequence Homology, Amino Acid
chemical_list: D008565:Membrane Proteins; D021382:Protein Sorting Signals