title: Transforming growth factor beta(2) increases in subretinal fluid in rhegmatogenous retinal detachment with subretinal strands.
abstract: OBJECTIVE
  To compare transforming growth factor (TGF) beta(2) levels in subretinal fluid of rhegmatogenous retinal detachment with or without subretinal strand formation.
  
  
  METHODS
  We assessed total and mature TGF-beta(2) levels in subretinal fluid obtained from 24 eyes with rhegmatogenous retinal detachment using an enzyme-linked immunosorbent assay. Group I comprised 18 specimens from eyes without subretinal strands, while group II comprised 6 specimens from eyes with subretinal strands.
  
  
  RESULTS
  Total and mature TGF-beta(2) levels were higher in group II than in group I (p=0.01 and p=0.07, respectively).
  
  
  CONCLUSIONS
  The concentrations of total and mature TGF-beta(2) were higher in cases of rhegmatogenous retinal detachment associated with subretinal strand formation compared to those without subretinal strand formation.
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hirase
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Ikeda
authors.forename: Chie
authors.initials: C
authors.lastname: Sotozono
authors.forename: Toru
authors.initials: T
authors.lastname: Yasuhara
authors.forename: Kan
authors.initials: K
authors.lastname: Koizumi
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
mesh_terms: D001826:Body Fluids / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005122:Exudates and Transudates / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000378:metabolism*; D053781:Transforming Growth Factor beta2
chemical_list: C509041:TGFB2 protein, human; D016212:Transforming Growth Factor beta; D053781:Transforming Growth Factor beta2