title: Genetic toxicity in surface water from Guaíba Hydrographic Region under the influence of industrial, urban and agricultural sewage in the Drosophila wing-spot test.
abstract: Mutagenic and recombinagenic activity of surface waters in the Guaíba Hydrographic Region (RS, Brazil) was investigated using the SMART in Drosophila melanogaster. Two positive results in Caí River (September 2000 and August 2001) and in Taquari River (August 2001 and February 2002)--linked to direct recombinagenic toxicants were observed. In Jacuí samples, an indirect mutagenic and recombinagenic action was detected in a September 2000 collection and a direct recombinational activity was observed in February 2002. Also in February 2002--samples from Dilúvio Brook and Guaíba Lake (GPC) were able to induce wing spots by mitotic recombinagenesis. The former sampling site showed toxicants to have a direct action, and the latter an increment in mitotic recombination that depended on metabolic action. The SMART wing test shows that all positive responses were mainly related to homologous mitotic recombination.
authors.affiliation: Laboratório de Mutagênese, Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Viviane Souza
authors.initials: VS
authors.lastname: do Amaral
authors.forename: Marialva
authors.initials: M
authors.lastname: Sinigaglia
authors.forename: Maria Luiza
authors.initials: ML
authors.lastname: Reguly
authors.forename: Heloisa Helena Rodrigues
authors.initials: HH
authors.lastname: de Andrade
mesh_terms: D000383:Agriculture; D000818:Animals; D001938:Brazil; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002947:Cities; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000235:genetics; D006863:Hydrogen-Ion Concentration; D007220:Industrial Waste / Q000009:adverse effects; D009152:Mutagenicity Tests / Q000379:methods; D009153:Mutagens / Q000633:toxicity*; D011995:Recombination, Genetic / Q000187:drug effects; D012722:Sewage; D013696:Temperature; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D014921:Wings, Animal / Q000187:drug effects
chemical_list: D007220:Industrial Waste; D009153:Mutagens; D012722:Sewage; D014874:Water Pollutants, Chemical