title: Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury.
abstract: Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared to dose related optic neuritis.
authors.affiliation: Section of Neurology, Department of Medicine, Aga Khan University, Karachi.
authors.forename: Sajjad
authors.initials: S
authors.lastname: Ali
authors.forename: Uzma
authors.initials: U
authors.lastname: Usman
authors.forename: Mohammad
authors.initials: M
authors.lastname: Wasay
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D018450:Disease Progression; D004977:Ethambutol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009902:Optic Neuritis / Q000139:chemically induced* / Q000175:diagnosis; D013997:Time Factors
chemical_list: D000995:Antitubercular Agents; D004977:Ethambutol