Selected rare, noninfectious syndromes associated with HIV infection.
Infrequent and sometimes treatable noninfectious syndromes associated with HIV disease include tenofovir-associated Fanconi syndrome, a proximal renal tubular disorder; pulmonary hypertension that appears to be due to HIV-driven inflammation resulting in endothelial proliferation; thrombotic thrombocytopenic purpura, characterized by intravascular coagulopathy; diffuse infiltrative lymphocytosis syndrome, which can affect multiple organs; and Castleman's disease, a lymphoproliferative disorder that usually occurs in a multicentric form with poor prognosis in HIV-infected patients. This article summarizes a presentation on the characteristics, diagnosis, treatment, and prognosis of these disorders by Molly E. Eaton, MD, at the International AIDS Society-USA course in Atlanta in March 2005.
Eaton
Molly E
ME
Emory University School of Medicine, Atlanta, GA, USA.
D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives; D019380:Anti-HIV Agents / Q000009:adverse effects; D005871:Castleman Disease / Q000821:virology; D005198:Fanconi Syndrome / Q000139:chemically induced; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000821:virology; D008218:Lymphocytosis / Q000821:virology; D063065:Organophosphonates / Q000009:adverse effects; D011696:Purpura, Thrombocytopenic / Q000821:virology; D000068698:Tenofovir
D019380:Anti-HIV Agents; D063065:Organophosphonates; D000068698:Tenofovir; D000225:Adenine