Non-invasive measurement of intraocular pressure by near-infrared spectroscopy.
OBJECTIVE
To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy.


METHODS
Experimental study.


METHODS
Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in diffuse reflectance out of the anterior chamber by near-infrared spectroscopy, IOP was determined and compared with the height of the water column which was varied between 0 cm and 100 cm.


RESULTS
In total, 363 near-infrared spectrometric measurement values were obtained. Correlating the near-infrared spectrometric measurements with the height of the water column showed a relationship with a correlation coefficient of r(2) = .858 and a steepness of the regression line of .96.


CONCLUSIONS
The results of the present pilot study suggest that near-infrared spectrometric tonometry may present a new technology for non-invasive and non-contact IOP measurement.
Weissbrodt
David
D
Mannheim University of Applied Sciences, Institute for Instrumental Analysis, Mannheim, Germany.
Müeller
Ralf
R
Backhaus
Juergen
J
Jonas
Jost B
JB
D000818:Animals; D007429:Intraocular Pressure; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013552:Swine; D014065:Tonometry, Ocular / Q000379:methods*