First clinical implant of the VentrAssist left ventricular assist system as destination therapy for end-stage heart failure.
The VentrAssist device left ventricular assist system, designed for permanent implantation, is a novel centrifugal pump with a hydrodynamically suspended rotor. The first human implant was into a 72-year-old man with New York Heart Association (NYHA) class IV heart failure due to idiopathic dilated cardiomyopathy. The implant and recovery were uneventful, and the patient survives at 17 months, is NYHA class II, and lives at home. This device shows promise in end-stage heart failure for permanent implantation and bridge to transplantation.
Esmore
Donald S
DS
Department of Cardiothoracic Surgery, Alfred Hospital, Prahran, Victoria, Australia.
Kaye
David
D
Salamonsen
Robert
R
Buckland
Mark
M
Rowland
Michael
M
Negri
Justin
J
Rowley
Yvonne
Y
Woodard
John
J
Begg
John R
JR
Ayre
Peter
P
Rosenfeldt
Franklin L
FL
D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000601:surgery*; D004867:Equipment Design; D004869:Equipment Safety; D005500:Follow-Up Studies; D006333:Heart Failure / Q000175:diagnosis / Q000601:surgery*; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000601:surgery*