Photodynamic therapy for choroidal neovascularization on late-onset fundus flavimaculatus.
OBJECTIVE
To report the features of three consecutive cases of patients affected with late-onset fundus flavimaculatus (FFM) complicated with choroidal new vessels (CNV) and treated with photodynamic therapy (PDT).


METHODS
Retrospective interventional case series.


METHODS
Three unrelated women (70- to 74-year-old) presented with unilateral decrease of central vision. Diagnosis of FFM and unilateral CNV was made after fundus examination and fluorescein angiography (FA). PDT was performed on the basis of FA features.


RESULTS
One to three PDTs were needed for the treatment of CNV. At the end of follow-up (15-24 months), no leakage was present and visual acuity was improved in these three cases.


CONCLUSIONS
Occurrence of CNV is a rare event in FFM. In these three eyes, PDT successfully stopped the progression of CNV and blocked leakage. We suggest considering PDT as a treatment for CNV in patients affected with FFM.
Souied
Eric H
EH
Clinique Ophtalmologique Universitaire de Créteil, Créteil, France. eric.souied@chicreteil.fr
Pawlak
Dominique
D
Algan
Michel
M
Sayag
David
D
Coscas
Gabriel
G
Soubrane
Gisele
G
D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D012164:Retinal Diseases / Q000150:complications / Q000188:drug therapy*; D012189:Retrospective Studies
D017319:Photosensitizing Agents