title: Current role of image-guided ablative therapies in lung cancer.
abstract: Lung cancer is the leading cause of cancer-related mortality in the USA. Until recently, lung cancer treatment options (dependent upon the tumor grading and staging at presentation, and patient comorbidities) included surgical resection (lobar or sublobar), chemotherapy and external-beam radiation therapy. While these options are still viewed as the primary standard of care, newer minimally invasive percutaneous ablative techniques such as radiofrequency ablation, microwave ablation and cryoablation are currently being examined as treatment alternatives, especially in the setting of the nonsurgical candidate. This review will focus on these three distinct thermoablative techniques in the percutaneous setting of lung cancer treatment.
authors.affiliation: Department of Diagnostic Imaging, Brown Medical School, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. csimon2@lifespan.org
authors.forename: Caroline J
authors.initials: CJ
authors.lastname: Simon
authors.forename: Damian E
authors.initials: DE
authors.lastname: Dupuy
mesh_terms: D017115:Catheter Ablation / Q000379:methods*; D003452:Cryosurgery / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008872:Microwaves / Q000627:therapeutic use*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D014057:Tomography, X-Ray Computed