[Effect of melatonin and radiation on pro- and antioxidant state of the liver and blood of rats].
The pro- and antioxidant state of the liver and blood of rats under the effect of melatonin and radiation in the total dose of 20 Gy has been studied. Irradiation by the broad fields intensifies the processes of lipoperoxidation and oxidative modification of proteins with simultaneous inhibition of the antioxidant protection. Melatonin administered against a background of radiation caused a distinctly expressed antioxidant effect.
Oliĭnyk
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Meshchyshen
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D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001769:Blood / Q000187:drug effects / Q000528:radiation effects; D002570:Ceruloplasmin / Q000378:metabolism; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D005720:Gamma Rays; D005954:Glucosephosphate Dehydrogenase / Q000097:blood / Q000378:metabolism; D005978:Glutathione / Q000097:blood / Q000378:metabolism; D005980:Glutathione Reductase / Q000097:blood / Q000378:metabolism; D008054:Lipid Peroxides / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects / Q000528:radiation effects; D051381:Rats; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism
D000975:Antioxidants; D008054:Lipid Peroxides; D005954:Glucosephosphate Dehydrogenase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin; D005980:Glutathione Reductase; D005978:Glutathione; D008550:Melatonin