Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates.
Fifty-eight enterohemorrhagic Escherichia coli O26:H11 or O26:NM (nonmotile) strains and 44 atypical enteropathogenic E. coli O26:H11 or O26:NM strains isolated from patients in 11 countries during 52 years share a common pool of non-stx virulence genes, fitness loci, and genotypic and phenotypic diagnostic markers. These findings indicate close relatedness between these pathotypes and provide a basis for their clinical laboratory diagnosis.
Bielaszewska
Martina
M
Institute for Hygiene and the National Consulting Laboratory on Hemolytic Uremic Syndrome, University Hospital Münster, Robert Koch Str. 41, 48149 Münster, Germany. mbiela@uni-muenster.de
Zhang
Wenlan
W
Tarr
Phillip I
PI
Sonntag
Anne-Katharina
AK
Karch
Helge
H
D004926:Escherichia coli / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D005243:Feces / Q000382:microbiology; D005838:Genotype; D006801:Humans; D010641:Phenotype; D014774:Virulence