title: [Acute myocardial infarction complicating primary antiphospholipid syndrome after aspirin and steroids withdrawal].
abstract: A 24-year-old woman, with known antiphospholid antibodies (APS), presented with an acute myocardial infarction (AMI) that occurred three months after delivery. No risk factors for arteriosclerosis and no past history of arterial/venous thrombosis were noted. During pregnancy, aspirin prophylaxis was prescribed and followed by steroids after caesarian section. Steroids withdrawal was followed by AMI. Immediate coronary angiography revealed thrombotic occlusion of the left descending coronary artery; PTCA was successfully performed. She was discharged with an antiplatelet and anticoagulant regimen. No recurrent coronary event occurred during follow-up.
authors.affiliation: Service de cardiologie, hôpital Cochin, université René-Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. karim.wahbi@cch.ap-hop-paris.fr
authors.forename: K
authors.initials: K
authors.lastname: Wahbi
authors.forename: E
authors.initials: E
authors.lastname: Salengro
authors.forename: L
authors.initials: L
authors.lastname: Galicier
authors.forename: L
authors.initials: L
authors.lastname: Guillevin
authors.forename: C
authors.initials: C
authors.lastname: Spaulding
authors.forename: S
authors.initials: S
authors.lastname: Weber
authors.forename: C
authors.initials: C
authors.lastname: Meune
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D016736:Antiphospholipid Syndrome / Q000150:complications*; D001241:Aspirin / Q000627:therapeutic use*; D003328:Coronary Thrombosis / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000517:prevention & control
chemical_list: D000305:Adrenal Cortex Hormones; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin