title: Helicobacter pylori associated with glossitis and halitosis.
abstract: BACKGROUND
  Helicobacter pylori is a curved microaerophilic Gram-negative bacterium considered as a risk factor for gastric cancer. The aim of this study was to find an association between burning sensations, acid taste, halitosis, and lingual hyperplasia with the effect of H. pylori on the mouth.
  
  
  METHODS
  A total of 124 subjects with different gastric diseases were studied: 46 patients with burning, halitosis and lingual dorsum hyperplasia and 78 patients with other diseases.
  
  
  RESULTS
  The detection of H. pylori in the oral cavity by histopathologic diagnosis and molecular biology was confirmed in 40/46 (87%) patients with burning, halitosis, and lingual hyperplasia, and in 2/78 (2.6%) subjects with other diseases. Chi2: 91.26 (p < .001) Mantel-Haenszel.
  
  
  CONCLUSIONS
  This trial showed an association between H. pylori and burning, halitosis, and lingual hyperplasia, and further considered this bacterium a risk factor for gastric infection.
authors.affiliation: Service of Stomatology, Center for Medical Education and Clinical Research (CEMIC), Buenos Aires, Argentina. liadler@intramed.net.ar
authors.forename: Isabel
authors.initials: I
authors.lastname: Adler
authors.forename: Valeria Cecilia
authors.initials: VC
authors.lastname: Denninghoff
authors.forename: Maria Inés
authors.initials: MI
authors.lastname: Alvarez
authors.forename: Alejandra
authors.initials: A
authors.lastname: Avagnina
authors.forename: Ricardo
authors.initials: R
authors.lastname: Yoshida
authors.forename: Boris
authors.initials: B
authors.lastname: Elsner
mesh_terms: D000328:Adult; D000368:Aged; D002054:Burning Mouth Syndrome / Q000382:microbiology*; D005260:Female; D005928:Glossitis / Q000382:microbiology*; D006209:Halitosis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D006965:Hyperplasia / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D014059:Tongue / Q000473:pathology*