title: [Primary lung cancer incidentally diagnosed in lung biopsy for diffuse pulmonary disease].
abstract: We here presented 2 cases of interstitial pneumonia with lung adenocarcinoma incidentally diagnosed by partially resected lung for diffuse pulmonary disease. CASE 1: A 78-year-old female was admitted to the hospital complaining of productive cough and general fatigue. The chest computed tomography (CT) revealed diffuse honey comb pattern in bilateral lung field especially in the right lower lung. Video-assisted thoracoscopic lung biopsy was performed and was diagnosed as diffuse spreading well differentiated adenocarcinoma. CASE 2: A 59-year-old male was admitted to the hospital complaining of dyspnea and general fatigue. The chest X-ray revealed right pneumothorax and chest CT revealed diffuse honey comb pattern and bullae in bilateral lung field and fibrous tumor-like lesion in the right middle lung. Video-assisted thoracoscopic lung biopsy was performed and was diagnosed as pulmonary fibrosis with papillary adenocarcinoma.
  
  
  CONCLUSIONS
  It is important to examine carefully the specimen obtained from thoracoscopic lung biopsy even if interstitial pneumonia is strongly suspected.
authors.affiliation: Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ishibashi
authors.forename: H
authors.initials: H
authors.lastname: Niikawa
authors.forename: I
authors.initials: I
authors.lastname: Ishida
authors.forename: Y
authors.initials: Y
authors.lastname: Hosaka
authors.forename: M
authors.initials: M
authors.lastname: Minowa
authors.forename: T
authors.initials: T
authors.lastname: Sado
authors.forename: T
authors.initials: T
authors.lastname: Tabata
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumura
authors.forename: T
authors.initials: T
authors.lastname: Kondo
authors.forename: S
authors.initials: S
authors.lastname: Ono
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D001706:Biopsy / Q000379:methods; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000473:pathology*; D008175:Lung Neoplasms / Q000175:diagnosis*; D008875:Middle Aged; D013902:Radiography, Thoracic; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed