Meiosis: organizing microtubule organizers.
During meiosis in fission yeast, the zygote nucleus undergoes microtubule-driven oscillatory movements that ultimately serve to promote genetic recombination. An essential component of this is a meiosis-specific consolidation of microtubule-organizing activity to the the spindle pole body, driven by the novel coiled-coil protein mcp6/hrs1p.
Sawin
Kenneth E
KE
Wellcome Trust Centre for Cell Biology, Edinburgh University, Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK. ken.sawin@ed.ac.uk
D018797:Cell Cycle Proteins / Q000378:metabolism*; D002467:Cell Nucleus / Q000502:physiology; D015966:Gene Expression Regulation, Fungal / Q000502:physiology*; D008540:Meiosis / Q000502:physiology*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D022101:Microtubule-Organizing Center / Q000378:metabolism*; D008954:Models, Biological; D011995:Recombination, Genetic / Q000502:physiology; D012568:Schizosaccharomyces; D008941:Spindle Apparatus / Q000378:metabolism*
D018797:Cell Cycle Proteins; D008869:Microtubule-Associated Proteins