Catalytic coupling of C-H and C-I bonds using pyridine as a directing group.
A method for the palladium-catalyzed arylation of pyridines and pyrazoles has been developed. Both aliphatic and aromatic C-H bonds may be functionalized using this method. A bromo substituent is tolerated on the aryl iodide coupling component. [reaction: see text]
Shabashov
Dmitry
D
Department of Chemistry, University of Houston, Houston, TX 77204, USA.
Daugulis
Olafs
O