title: [Pathophysiology of Barrett's esophagus--motility disorder of esophagus].
abstract: Barrett's esophagus is a premalignant condition of reflux esophagitis and the prevalence is increasing in western countries. Although pathogenesis of Barrett's esophagus is still unknown, several studies have indicated that Barrett's esophagus is related to increased acid reflux through decreased lower esophageal sphincter tone and reduced esophageal contractions. In this article recent studies of Barrett's esophagus on pathophysiology of esophageal motility is reviewed.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School.
authors.forename: Ken
authors.initials: K
authors.lastname: Haruma
authors.forename: Keisuke
authors.initials: K
authors.lastname: Honda
authors.forename: Tomoari
authors.initials: T
authors.lastname: Kamata
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kusunoki
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Sugiu
authors.forename: Aki
authors.initials: A
authors.lastname: Tanaka
authors.forename: Jiro
authors.initials: J
authors.lastname: Hata
mesh_terms: D001471:Barrett Esophagus / Q000209:etiology / Q000503:physiopathology*; D049630:Esophageal Sphincter, Lower / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000209:etiology; D005769:Gastrointestinal Motility; D006801:Humans; D009119:Muscle Contraction; D009129:Muscle Tonus; D009130:Muscle, Smooth / Q000503:physiopathology