title: Usefulness of magnetic resonance sialography in patients with juvenile Sjögren's syndrome.
abstract: OBJECTIVE
  Sialography is an important means for evaluating parotid gland damage in patients with Sjögren's syndrome (SS). However, 'conventional' X-ray sialography is invasive and sometimes difficult to perform and repeat, especially for young patients. Recently, magnetic resonance (MR) sialography has been used in adult SS patients. In this study, we investigated the usefulness of MR sialography for evaluating parotid gland damage in juvenile SS.
  
  
  METHODS
  Eight young patients suffering from SS were studied. MR sialography and X-ray sialography were performed simultaneously in the same patients. The images obtained by both methods were assessed with Rubin-Holt staging.
  
  
  RESULTS
  MR sialography detected ductal dilatation in 5 of 8 patients, while it was detected in 7 of 8 patients by X-ray sialography. The stages were the same in 4 patients by both methods. In 3 patients, the stages on X-ray sialography were higher than those on MR sialography; in 1 patient, the stage on MR sialography was higher. The correlation between the stages determined by the 2 methods was 0.85. There were no side effects in MR sialography, whereas 3 patients complained of pain during X-ray sialography.
  
  
  CONCLUSIONS
  MR sialography can evaluate Stage II approximately III parotid gland damage in juvenile SS. Although MR sialography cannot detect subtle changes in the duct, it has no side effects and can be performed repeatedly in young patients. We propose that MR sialography be chosen as the first tool for diagnosing and during follow-up of the status of the glands in juvenile SS.
authors.affiliation: Department of Pediatrics, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tomiita
authors.forename: T
authors.initials: T
authors.lastname: Ueda
authors.forename: H
authors.initials: H
authors.lastname: Nagata
authors.forename: E
authors.initials: E
authors.lastname: Tanabe
authors.forename: N
authors.initials: N
authors.lastname: Shimojo
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Motoori
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Kohno
mesh_terms: D000293:Adolescent; D000328:Adult; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010306:Parotid Gland / Q000000981:diagnostic imaging* / Q000473:pathology*; D011379:Prognosis; D015203:Reproducibility of Results; D018987:Salivary Ducts / Q000473:pathology; D012796:Sialography / Q000379:methods; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology*