Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies.
Broillet
A
A
Bracco Research, Geneva, Switzerland. anne.broillet@brg.bracco.com
Hantson
J
J
Ruegg
C
C
Messager
T
T
Schneider
M
M
D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage*; D000068338:Everolimus; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000000981:diagnostic imaging*; D008833:Microcirculation / Q000187:drug effects; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D010743:Phospholipids / Q000008:administration & dosage*; D051381:Rats; D011916:Rats, Inbred F344; D020123:Sirolimus / Q000031:analogs & derivatives / Q000494:pharmacology; D013459:Sulfur Hexafluoride / Q000008:administration & dosage*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology; D016217:Ultrasonography, Mammary / Q000379:methods*
D003287:Contrast Media; D010743:Phospholipids; D014409:Tumor Necrosis Factor-alpha; C420843:contrast agent BR1; D000068338:Everolimus; D020123:Sirolimus; D013459:Sulfur Hexafluoride