[Pathogenetical features of the first period of trauma disease with acute respiratory insufficiency].
The pathogenetical features of acute respiratory insufficiency (ARI) were studied as a clinical form of the first period of the trauma disease (TD)--the period of acute impairments of the important for life functions (the first 8-12 h after trauma). In 17 casualties with a severe combined trauma the severity of the first period of the disease depended on the ARI caused by a serious injury of the chest not accompanied by a direct injury of the heart. It was shown that ARI is an independent clinical form of the first period of TD. The indices of the systemic hemodynamics in ARI are within the limits of the normal values. ARI resulting from the "primary" injury of the lungs results in a decreased delivery of oxygen to the tissues and of its consumption. When ARI takes place during the first period of TD the metabolic function of the lungs is sharply suppressed and pronounced endotoxemia is observed.
Gumanenko
E K
EK
Nemchenko
N S
NS
Goncharov
A V
AV
Pashkovskiĭ
E V
EV
D000208:Acute Disease; D000328:Adult; D001784:Blood Gas Analysis; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology*; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood; D010992:Plethysmography, Impedance; D012131:Respiratory Insufficiency / Q000453:epidemiology* / Q000378:metabolism / Q000503:physiopathology*; D013997:Time Factors; D014947:Wounds and Injuries / Q000453:epidemiology*
D010100:Oxygen