title: A comparative study of superoxide dismutase, catalase, and glutathione peroxidase activities and nitrate levels in vitiligo patients.
abstract: BACKGROUND
  Several groups have shown the involvement of oxidative stress in the pathophysiology of vitiligo.
  
  
  METHODS
  In this study, we examined the erythrocyte and plasma activities of glutathione peroxidase and Cu/Zn superoxide dismutase, plasma nitrite/nitrate levels, and erythrocyte catalase activity in 23 vitiligo patients and 25 controls.
  
  
  RESULTS
  The results show that erythrocyte superoxide dismutase activity and plasma nitrite/nitrate levels are high in vitiligo patients.
  
  
  CONCLUSIONS
  Our study confirms that oxidative stress is involved in the pathophysiology of vitiligo, as indicated by the high levels of erythrocyte superoxide dismutase activity and plasma nitrite/nitrate.
authors.affiliation: Department of Dermatology, University of Inonu, Malatya, Turkey. hazneci@hotmail.com
authors.forename: Ersoy
authors.initials: E
authors.lastname: Hazneci
authors.forename: Aysun Bay
authors.initials: AB
authors.lastname: Karabulut
authors.forename: Cetin
authors.initials: C
authors.lastname: Oztürk
authors.forename: Kadir
authors.initials: K
authors.lastname: Batçioğlu
authors.forename: Gürsoy
authors.initials: G
authors.lastname: Doğan
authors.forename: Semsettin
authors.initials: S
authors.lastname: Karaca
authors.forename: Muammer
authors.initials: M
authors.lastname: Eşrefoğlu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002374:Catalase / Q000097:blood; D004798:Enzymes / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000097:blood*; D009569:Nitric Oxide / Q000097:blood; D009573:Nitrites / Q000097:blood; D013482:Superoxide Dismutase / Q000097:blood; D014820:Vitiligo / Q000097:blood* / Q000201:enzymology
chemical_list: D004798:Enzymes; D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase