Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence.
Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence.
Tang
Dong-Jie
DJ
College of Life Science and Technology, Guangxi University, 100 Daxue Road, Nanning, Guangxi 530004, People's Republic of China.
He
Yong-Qiang
YQ
Feng
Jia-Xun
JX
He
Bao-Ren
BR
Jiang
Bo-Le
BL
Lu
Guang-Tao
GT
Chen
Baoshan
B
Tang
Ji-Liang
JL
D001483:Base Sequence; D017931:DNA Primers; D003998:Dicarboxylic Acids / Q000378:metabolism; D005943:Gluconeogenesis / Q000235:genetics*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010935:Plant Diseases / Q000382:microbiology; D018515:Plant Leaves / Q000382:microbiology; D011773:Pyruvates / Q000378:metabolism; D017384:Sequence Deletion; D014774:Virulence; D016959:Xanthomonas campestris / Q000235:genetics / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity*
D017931:DNA Primers; D003998:Dicarboxylic Acids; D011773:Pyruvates