title: Identification of unique B/C recombinant strains of HIV-1 in the southern state of Karnataka, India.
abstract: We characterized the molecular nature of a large number of primary HIV-1 isolates in the four southern states of India. In addition to confirming a predominance of subtype C infection, for the first time we identified three B/C recombinant viruses in a subset of 115 samples. Unexpectedly, env sequences of two of the three B/C recombinants phylogenetically clustered with subtype B strains of the USA. The determination of the real incidence of the recombinant viruses is of importance.
authors.affiliation: Molecular Virology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560 064, India.
authors.forename: Nagadenahalli Byrareddy
authors.initials: NB
authors.lastname: Siddappa
authors.forename: Prashanta Kumar
authors.initials: PK
authors.lastname: Dash
authors.forename: Anita
authors.initials: A
authors.lastname: Mahadevan
authors.forename: Anita
authors.initials: A
authors.lastname: Desai
authors.forename: Narayana
authors.initials: N
authors.lastname: Jayasuryan
authors.forename: Vasanthapuram
authors.initials: V
authors.lastname: Ravi
authors.forename: Parthasarathy
authors.initials: P
authors.lastname: Satishchandra
authors.forename: Susarla K
authors.initials: SK
authors.lastname: Shankar
authors.forename: Udaykumar
authors.initials: U
authors.lastname: Ranga
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D011995:Recombination, Genetic