Brain apparent diffusion coefficient decrease during correction of severe hypernatremic dehydration.
We report on the brain diffusion MR imaging findings in a neonate with severe hypernatremic dehydration, which resulted in cerebral edema (osmotic edema) and in apparent diffusion coefficient decrease, despite a careful and slow rehydration. This report provides in vivo insight into nervous cell response to osmotic challenge.
Righini
Andrea
A
Department of Radiology and Neuroradiology, Istituti Clinici di Perfezionamento, Milan, Italy. neurorad@icp.mi.it
Ramenghi
Luca
L
Zirpoli
Salvatore
S
Mosca
Fabio
F
Triulzi
Fabio
F
D001921:Brain / Q000473:pathology*; D001929:Brain Edema / Q000209:etiology; D003681:Dehydration / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D038524:Diffusion Magnetic Resonance Imaging; D017352:Echo-Planar Imaging; D005440:Fluid Therapy; D006801:Humans; D006955:Hypernatremia / Q000150:complications*; D007231:Infant, Newborn; D008297:Male