title: Standard anesthetic technique for middle ear surgical procedures: a comparison of desflurane and sevoflurane.
abstract: OBJECTIVE
  This study was designed to compare desflurane and sevoflurane anesthesia for middle ear microsurgery.
  
  
  METHODS
  One hundred healthy adults undergoing middle ear surgery were assigned to receive either desflurane or sevoflurane as their anesthetic. Intraoperative hemodynamics and BIS numbers were recorded. Hemodynamics, pain, nausea/vomiting, discharge readiness, and other parameters were compared postoperatively and 24 hours later.
  
  
  RESULTS
  No intraoperative differences were noted except in BIS scores which trended lower with desflurane. PACU blood pressures were higher after desflurane but pain scores, nausea/vomiting, rescue anti-emetics, recovery scores, and discharge times were similar. A significant difference was noted in anesthetic costs (desflurane > sevoflurane), and in patients with the lowest BIS scores associated with more nausea/vomiting.
  
  
  CONCLUSIONS
  Both anesthetics may be used for ototic surgery but propofol anesthesia should still be considered in patients with a history of emetic sequelae.
  
  
  CONCLUSIONS
  Short-acting inhalational anesthetics produce excellent operating conditions and reduce costs for otologic surgery.
authors.affiliation: Department of Anesthesiology, Loyola University Medical Center, Maywood, IL 60153, USA. wjellis@lumc.edu
authors.forename: W Scott
authors.initials: WS
authors.lastname: Jellish
authors.forename: Kevin
authors.initials: K
authors.lastname: Owen
authors.forename: Steven
authors.initials: S
authors.lastname: Edelstein
authors.forename: Elaine
authors.initials: E
authors.lastname: Fluder
authors.forename: John P
authors.initials: JP
authors.lastname: Leonetti
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000592:standards*; D000762:Anesthesia Recovery Period; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D000077335:Desflurane; D004432:Ear, Middle / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000031:analogs & derivatives*; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D008875:Middle Aged; D010036:Otolaryngology / Q000379:methods; D011336:Probability; D011446:Prospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D000077335:Desflurane; D007530:Isoflurane