Gadobenate dimeglumine (MultiHance) in MR imaging of the CNS: studies to assess the benefits of a high relaxivity contrast agent.
The use of Gd-BOPTA as a contrast agent for morphological and functional MR imaging allows improved detection and delineation of CNS lesions compared to conventional gadolinium agents. This results not only to more confident diagnosis, but also to a substantially improved differential diagnosis process. The higher relaxivity of Gd-BOPTA also helps to optimize functional MR imaging studies e.g. perfusion MRI and dynamic MR angiographic protocols.
Essig
Marco
M
German Cancer Research Center, Heidelberg, Germany.
D016543:Central Nervous System Neoplasms / Q000175:diagnosis*; D002560:Cerebrovascular Circulation; D017322:Clinical Trials, Phase II as Topic; D003287:Contrast Media / Q000008:administration & dosage*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008536:Meglumine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D009942:Organometallic Compounds / Q000008:administration & dosage*; D012680:Sensitivity and Specificity
D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine