title: Determination of mono- to octachlorobiphenyls in fish oil using florisil adsorption followed by headspace solid-phase microextraction and gas chromatography with time-of-flight mass spectrometric detection.
abstract: A simple and reliable method for the determination of polychlorinated biphenyls (PCBs) from mono- to octachlorobiphenyls in fish oil for dietary supplement is described. The method combines Florisil clean up and headspace solid-phase microextraction on 65 microm polydimethylsiloxane-divinylbenzene (PDMS-DVB). Analyte detection was carried out using GC-time-of-flight mass spectrometry (GC-TOF-MS). Fifty three PCB congeners including the seven indicator PCBs (IUPAC Nos. 28, 52, 101, 118, 138, 153 and 180) were analyzed. Under optimal conditions, the method detection limit (MDL) of each congener in the range from 0.8 to 31 ng/g was found. A certified reference material (BCR-349) was analyzed and it showed good agreement with the certified data.
authors.affiliation: Advanced Analysis Center, Korea Institute of Science and Technology, P.O. Box 131 Cheongryangri, Seoul 130-650, South Korea.
authors.forename: Mary Rose R
authors.initials: MR
authors.lastname: Agustin
authors.forename: Hyun-Mee
authors.initials: HM
authors.lastname: Park
authors.forename: Soon-Min
authors.initials: SM
authors.lastname: Hong
authors.forename: Jae-Chun
authors.initials: JC
authors.lastname: Ryu
authors.forename: Kang-Bong
authors.initials: KB
authors.lastname: Lee
mesh_terms: D000327:Adsorption; D005395:Fish Oils / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D017633:Magnesium Silicates / Q000737:chemistry*; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D015203:Reproducibility of Results
chemical_list: D005395:Fish Oils; D017633:Magnesium Silicates; C005013:Florisil; D011078:Polychlorinated Biphenyls