Familial arachnoid cysts.
Arachnoid cysts are a relatively common incidental finding on neuroimaging studies of the brain. Although most cases are sporadic, there have been some reports of arachnoid cysts in several members of the same family. This report describes two additional families with three members affected in each one. Both families had members with arachnoid cysts in two consecutive generations. In one of the families, arachnoid cysts were associated with a deletion in the long arm of chromosome 16, an association not described previously. These descriptions suggest that in some cases arachnoid cysts may have a genetic basis.
Arriola
Gema
G
Pediatric Neurology Section, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
de Castro
Pedro
P
Verdú
Alfonso
A
D016080:Arachnoid Cysts / Q000235:genetics* / Q000473:pathology*; D002675:Child, Preschool; D002872:Chromosome Deletion; D002885:Chromosomes, Human, Pair 16; D005192:Family Health; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male