Relapse with transformation of lupus nephritis in a transplant kidney.
Lupus nephritis is a constellation of different renal histologies, characterized by an immune complex mediated glomerular disease. Histological transformation in lupus nephritis usually occurs from a mild mesangial proliferative glomerulonephritis to a more aggressive diffuse proliferative lesion. We present a case of relapsed systemic lupus erythematosus (SLE) in a renal transplant recipient in which there was a histological transformation from the original diffuse proliferative lupus nephritis in the native kidneys to a membranous lupus nephritis in the renal transplant.
Thomas
M
M
Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Blennerhassett
J
J
Walker
R
R
D000328:Adult; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008181:Lupus Nephritis / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D011183:Postoperative Complications; D012008:Recurrence; D019737:Transplants