Diastereoselective addition of 2H-2-oxo-1,4,2-oxazaphosphinanes to aldehydes and imines.
[reaction: see text] Diastereoselective additions of 2-hydrogeno-2-oxo-1,4,2-oxazaphosphinanes to aldehydes and imines are described. alpha,alpha'-Diaminophosphinic and alpha-amino-alpha'-hydroxyphosphinic derivatives were obtained with de's ranging from 24 to 90%.
Pirat
Jean-Luc
JL
Laboratoire de Chimie Organique, UMR5076-ENSCM, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex 5, France. pirat@cit.enscm.fr
Monbrun
Jérôme
J
Virieux
David
D
Volle
Jean-Noël
JN
Tillard
Monique
M
Cristau
Henri-Jean
HJ
D000447:Aldehydes / Q000138:chemical synthesis; D007097:Imines / Q000138:chemical synthesis; D008968:Molecular Conformation; D010721:Phosphinic Acids / Q000138:chemical synthesis*
D000447:Aldehydes; D007097:Imines; D010721:Phosphinic Acids