A guideline for analyzing circadian wheel-running behavior in rodents under different lighting conditions.
Most behavioral experiments within circadian research are based on the analysis of locomotor activity. This paper introduces scientists to chronobiology by explaining the basic terminology used within the field. Furthermore, it aims to assist in designing, carrying out, and evaluating wheel-running experiments with rodents, particularly mice. Since light is an easily applicable stimulus that provokes strong effects on clock phase, the paper focuses on the application of different lighting conditions.
Jud
Corinne
C
Division of Biochemistry, Department of Medicine, University of Fribourg, 1700 Fribourg, Switzerland.
Schmutz
Isabelle
I
Hampp
Gabriele
G
Oster
Henrik
H
Albrecht
Urs
U