title: Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass.
abstract: OBJECTIVE
  We investigated the diagnostic value of a new system, the Innotrac Aio! immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays.
  
  
  RESULTS
  The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays.
  
  
  CONCLUSIONS
  There is strong evidence that the Innotrac Aio! system for cTnI measurement can be used reliably.
authors.affiliation: Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany. M.Weber@kerckhoff-klinik.de
authors.forename: Michael
authors.initials: M
authors.lastname: Weber
authors.forename: Matthias
authors.initials: M
authors.lastname: Rau
authors.forename: Katharina
authors.initials: K
authors.lastname: Madlener
authors.forename: Albrecht
authors.initials: A
authors.lastname: Elsaesser
authors.forename: Dragic
authors.initials: D
authors.lastname: Bankovic
authors.forename: Veselin
authors.initials: V
authors.lastname: Mitrovic
authors.forename: Christian
authors.initials: C
authors.lastname: Hamm
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood*; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000097:blood*; D052279:Creatine Kinase, MB Form / Q000032:analysis*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D009211:Myoglobin / Q000032:analysis*; D011933:Reagent Kits, Diagnostic; D020107:Troponin T / Q000032:analysis*
chemical_list: D015415:Biomarkers; D009211:Myoglobin; D011933:Reagent Kits, Diagnostic; D020107:Troponin T; D052279:Creatine Kinase, MB Form