Adie's pupils in paraneoplastic ganglionopathy with ANNA-1.
Autonomic disturbances are common in patients with paraneoplastic syndromes associated with type-1 antineuronal nuclear autoantibodies (ANNA-1), although pupillary disturbances are infrequent. The authors describe a patient with ANNA-1 associated paraneoplastic sensory neuronopathy and bilateral Adie's pupils.
Campellone
Joseph V
JV
Department of Medicine, Division of Neurology, Cooper University Hospital, 3 Cooper Plaza, Suite 320, Camden, NJ 08103, USA. campellone-joseph@cooperhealth.edu
Hageboutros
Alexandre
A
D000368:Aged; D000912:Antibodies, Neoplasm / Q000276:immunology*; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology*; D001379:Azathioprine / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000276:immunology; D020233:Gait Disorders, Neurologic / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology; D005726:Ganglia, Parasympathetic / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007498:Iris / Q000294:innervation / Q000503:physiopathology; D008175:Lung Neoplasms / Q000150:complications* / Q000276:immunology; D008297:Male; D009802:Oculomotor Nerve / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology; D020361:Paraneoplastic Syndromes, Nervous System / Q000175:diagnosis / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology; D011680:Pupil; D012678:Sensation Disorders / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology; D015845:Tonic Pupil / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology*; D016896:Treatment Outcome
D000912:Antibodies, Neoplasm; D007166:Immunosuppressive Agents; D001379:Azathioprine