title: Shortcut to fmoc-protected phosphinic pseudodipeptidic blocks.
abstract: A three-component condensation reaction of Fmoc-carbamate, aldehydes, and alkylphosphinic acids provides a new, direct, and efficient method for synthesizing Fmoc-protected phosphinic pseudodipeptidic blocks, directly usable for solid-phase peptide synthesis. [reaction: see text]
authors.affiliation: Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece.
authors.forename: Magdalini
authors.initials: M
authors.lastname: Matziari
authors.forename: Athanasios
authors.initials: A
authors.lastname: Yiotakis
mesh_terms: D020650:Combinatorial Chemistry Techniques; D005449:Fluorenes / Q000737:chemistry*; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis*; D010721:Phosphinic Acids / Q000737:chemistry*
chemical_list: D005449:Fluorenes; D010455:Peptides; D010721:Phosphinic Acids