title: [Anti-thrombotic therapy of acute coronary syndromes without ST elevation].
abstract: Unstable angina is the most frequent acute coronary syndrome. Risk stratification to predict coronary morbidity and mortality and the risk of major hemorrhage is the key element of the medical approach. Combined antithrombotic therapy (including aspirin, clopidogrel, low-molecular-weight heparin and, possibly, glycoprotein IIb/IIIa receptor antagonists) has led to a substantial reduction in major coronary events; tolerance is good because the treatment is brief and aggressive. Combined antithrombotic therapy also increases the benefit of early invasive strategies including coronary angiogram with stent-based percutaneous coronary angioplasty.
authors.affiliation: Institut de Cardiologie, Groupe Hospitalier Pitié-Salpétrière, AP-HP, 47, boulevard de l'Hôpital, 75013 Paris. gilles.montalescot@psl.ap-hop-paris.fr
authors.forename: Gilles
authors.initials: G
authors.lastname: Montalescot
authors.forename: Laurent
authors.initials: L
authors.lastname: Payot
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Collet
authors.forename: Rémi
authors.initials: R
authors.lastname: Choussat
authors.forename: Farzin
authors.initials: F
authors.lastname: Beygui
mesh_terms: D000789:Angina, Unstable / Q000628:therapy*; D000800:Angioplasty, Balloon; D000925:Anticoagulants / Q000627:therapeutic use*; D003328:Coronary Thrombosis / Q000517:prevention & control*; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000628:therapy*; D015607:Stents
chemical_list: D000925:Anticoagulants