title: [Otolith function tests--a differentiated, quality-assured screening system].
abstract: BACKGROUND
  More than 30% of all otogenic vestibular disorders are related to isolated macular dysfunction. Videooculographic examination techniques for the otolith-ocular reflex, e. g. by means of eccentric rotation tests, are not widely used in clinical routine as these put a considerable strain on technical and staff resources. Thus, there is a considerable risk of "false negative" classification of vertigo disorders being labelled as "non-otogenic". By means of vestibular-evoked myogenic potentials (VEMPs) and caloric irrigation in prone and supine position, several examination techniques for a side-related investigation of macula-induced vestibulo-ocular reflexes are available. The objective of this study is to compare and evaluate these techniques as screening tests.
  
  
  METHODS
  In 32 patients with vestibular disorders we performed investigations for VEMPs, eccentric rotation tests, as well as caloric irrigation for macular reaction in prone and supine position. In addition, we performed other audiologic and vestibular function tests which were complemented by the clinical course in order to differentiate each case between otogenic and non-otogenic vertigo with or without macular affection.
  
  
  RESULTS
  The technical feasibility as well as patients' acceptance for VEMP testing is better than for eccentric rotation tests. The sensitivity index for VEMPs (89%) as well as for caloric irrigation in prone and supine position for macular examination (71%) is satisfactory. However, the specificity of VEMPs is inferior (53%) to eccentric rotation (100%).
  
  
  CONCLUSIONS
  Both the examination for VEMPs as well as caloric macular testing in prone and supine position carry features which make them feasible for screening, even though these two procedures test for two different parts of the otolith system. However, to confirm a diagnosis and to set up a therapeutic concept for macular function disorders, eccentric rotation should be added.
authors.affiliation: Klinik für Hals-, Nasen- und Ohrenheilkunde und Plastische Kopf- und Halschirurgie des Universitätsklinikum Aachen. pduewel@ukaachen.de
authors.forename: P
authors.initials: P
authors.lastname: Düwel
authors.forename: L E
authors.initials: LE
authors.lastname: Walther
authors.forename: M
authors.initials: M
authors.lastname: Sanders
authors.forename: J
authors.initials: J
authors.lastname: Ilgner
authors.forename: M
authors.initials: M
authors.lastname: Westhofen
mesh_terms: D002150:Caloric Tests; D003937:Diagnosis, Differential; D005072:Evoked Potentials, Auditory; D005240:Feasibility Studies; D006801:Humans; D017120:Nystagmus, Optokinetic; D010037:Otolithic Membrane / Q000502:physiology* / Q000503:physiopathology; D016684:Prone Position; D011785:Quality Assurance, Health Care; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016683:Supine Position; D014717:Vertigo / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D015837:Vestibular Diseases / Q000175:diagnosis*; D014724:Vestibular Function Tests; D014741:Video Recording