[Subacute ischemia of the lower limb revealing hyperhomocysteinemia in a young woman].
A 51-year-old woman had no known cardiovascular risk factor. She presented with bilateral calf intermittent claudication from February. She was hospitalized in August for acute right leg ischemia without loss of sensorymotor functions, following angiography by one week. She had an occlusion of both superficial femoral arteries and abdominal aorta thrombus, plausible source for embolism. Her condition quickly improved with heparin and iloprost infusion. Since the aortic thrombus was removed on ultrasound, aortic surgery was not performed at this time. Investigations showed hyperhomocysteinemia (25 microg/L after overnight fasting and 115 after methionin load) and decrease in folic acid. This report highlights the occurrence of severe arterial disease in young women with high serum homocysteine levels.
Litalien
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Service de Médecine Interne et Médecine Vasculaire, Hôpital Saint-André, 1 rue Jean Burguet, 33075 Bordeaux. joel.constans@chu-bordeaux.fr
Constans
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J
Riche
A
A
Barcat
D
D
Conri
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C
D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000175:diagnosis*; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology*; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D011859:Radiography