Usefulness of prophylactic transcatheter arterial infusion of anticancer agents with lipiodol to prevent recurrence of hepatocellular carcinoma after hepatic resection.
To improve the prognosis after hepatectomy for HCC, repeated postoperative transcatheter arterial infusions of anticancer drugs and lipiodol (TAI) were given. TAI may be effective as an adjuvant therapy for prevention of residual liver recurrence after hepatectomy, probably by suppression of the development of intrahepatic micrometastases rather than of multicentric carcinogenesis.
Togo
Shinji
S
Department of Surgery II, Yokohama City University School of Medicine, Yokohama, Japan. togo@med.yokohama-cu.ac.jp
Tanaka
Kuniya
K
Masui
Hidenobu
H
Matsuo
Kenichi
K
Morioka
Daisuke
D
Kurosawa
Haruki
H
Miura
Yasuhiko
Y
Endo
Itaru
I
Sekido
Hitoshi
H
Shimada
Hiroshi
H
D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D018890:Chemoprevention; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects*; D006801:Humans; D007261:Infusions, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology / Q000517:prevention & control*
D000970:Antineoplastic Agents; D003287:Contrast Media; D007459:Iodized Oil