title: Gastrointestinal involvement in POEMS syndrome: a novel clinical manifestation.
abstract: POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is characterised by a rare multisystem disorder of unknown pathogenesis. Although its pathophysiology is not well understood, overexpression of proinflammatory cytokines has been implicated. Gastrointestinal system disorders have not been reported among the components of the syndrome. A case is reported of POEMS syndrome with gastrointestinal involvement shown by gastrointestinal endoscopy.
authors.affiliation: Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Dogan
authors.forename: Y
authors.initials: Y
authors.lastname: Beyazit
authors.forename: A
authors.initials: A
authors.lastname: Shorbagi
authors.forename: S
authors.initials: S
authors.lastname: Köklü
authors.forename: S
authors.initials: S
authors.lastname: Ustunel
authors.forename: N
authors.initials: N
authors.lastname: Guler
authors.forename: A
authors.initials: A
authors.lastname: Uner
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D016878:POEMS Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone