[Understanding in treating gliomas: an adequate experimental model for each question].
Malignant glioma are especially difficult to model in vivo. Here we review the most recent strategies for designing relevant models of glioma. These should greatly contribute to identification of new tumor regulating molecules and facilitate testing of inhibitors to be used in therapeutical trials as well as the drug resistance that they might confer.
Javerzat
Sophie
S
Inserm EMI113, avenue des Facultés, 33405 Talence.
Bikfalvi
Andréas
A
Hagedorn
Martin
M
D000818:Animals; D001932:Brain Neoplasms / Q000235:genetics / Q000473:pathology; D002642:Chick Embryo; D049033:Chorioallantoic Membrane; D004195:Disease Models, Animal; D005910:Glioma / Q000235:genetics / Q000473:pathology; D006801:Humans; D051379:Mice; D046228:Microarray Analysis / Q000379:methods; D009368:Neoplasm Transplantation / Q000379:methods; D051381:Rats