title: Antifungal activities of propolis collected by different races of honeybees against yeasts isolated from patients with superficial mycoses.
abstract: Yeasts isolated from patients with superficial mycoses were tested against propolis samples collected from different regions and honeybee races. The minimum inhibitory concentration (MIC) values obtained using the agar dilution methods were compared to the diameters of growth inhibition zones by using the disk diffusion method. The results showed that Candida albicans, C. glabrata, Trichosporon spp., and Rhodotorula sp. were susceptible to low concentrations of propolis, the latter showing a higher susceptibility. Relative to the other propolis tested, the propolis sample collected by Apis mellifera caucasica possessed the highest antifungal activity against all of the superficial mycoses. In contrast, the propolis samples collected by A.m. carnica and A.m. anatolica were the least active samples. Also, the propolis sample from the Adana region is more active than samples from other regions. An increase of MIC values was accompanied by a decrease of growth inhibition zone diameters.
authors.affiliation: Erciyes University, Safiye Cikrikcioglu Vocational College, Department of Animal Science, Kayseri, Turkey. silicis@erciyes.edu.tr
authors.forename: Sibel
authors.initials: S
authors.lastname: Silici
authors.forename: Nedret A
authors.initials: NA
authors.lastname: Koç
authors.forename: Demet
authors.initials: D
authors.lastname: Ayangil
authors.forename: Soner
authors.initials: S
authors.lastname: Cankaya
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001516:Bees / Q000235:genetics / Q000502:physiology; D002176:Candida albicans / Q000187:drug effects* / Q000302:isolation & purification; D003881:Dermatomycoses / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D011429:Propolis / Q000302:isolation & purification / Q000494:pharmacology*; D012248:Rhodotorula / Q000187:drug effects* / Q000302:isolation & purification; D013045:Species Specificity; D014250:Trichosporon / Q000187:drug effects* / Q000302:isolation & purification; D014421:Turkey
chemical_list: D000935:Antifungal Agents; D011429:Propolis