Influence of apical patency and filling material on healing process of dogs' teeth with vital pulp after root canal therapy.
The purpose of this study was to investigate the periapical healing process of dogs' teeth with or without apical patency and after root canal filling with two types of sealers. Forty roots of premolars and incisors were utilized. The root canals were over-instrumented and dressed with a corticosteroid-antibiotic solution for 7 days to obtain ingrowth of periapical connective tissue into the canals. After this period, the tissue was removed in half of the specimens (groups with patency) and preserved in the other half (groups without patency). Canals were filled by lateral condensation technique with gutta-percha points and either a calcium hydroxide-based sealer (Sealer Plus) or a Grossman's cement (Fill Canal). The animals were killed by anesthetic overdose 60 days after the endodontic treatment and anatomic pieces were obtained and prepared for histologic examination. Data were evaluated in a blind analysis on the basis of several histomorphologic parameters. The groups without patency had better results (p=0.01) than those in which the ingrown connective tissue was removed. Comparing the sealers, Sealer Plus had significantly better results (p=0.01) than Fill Canal. In conclusion, both the apical patency (presence or absence) and the type of root canal filling material influenced the periapical healing process in dogs' teeth with vital pulp after root canal treatment. The use of a calcium hydroxide-based sealer in teeth without apical patency yielded the best results among the experimental conditions proposed.
Holland
Roberto
R
Department of Restorative Dentistry, Faculty of Dentistry of Araçatuba, UNESP, Araçatuba, SP, Brazil. rholland@foa.unesp.br
Sant'Anna Júnior
Arnaldo
A
Souza
Valdir de
Vd
Dezan Junior
Eloi
E
Otoboni Filho
José Arlindo
JA
Bernabé
Pedro Felício Estrada
PF
Nery
Mauro Juvenal
MJ
Murata
Sueli Satomi
SS
D000704:Analysis of Variance; D000818:Animals; D001466:Barium Sulfate / Q000494:pharmacology; D001729:Bismuth / Q000494:pharmacology; D001881:Borates / Q000494:pharmacology; D002126:Calcium Hydroxide / Q000494:pharmacology; D003739:Dental Cementum / Q000187:drug effects; D003782:Dental Pulp / Q000502:physiology; D004285:Dogs; D004338:Drug Combinations; D005054:Eugenol / Q000494:pharmacology; D010513:Periodontal Ligament / Q000187:drug effects; D012117:Resins, Synthetic / Q000494:pharmacology; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012389:Root Canal Obturation / Q000379:methods*; D018709:Statistics, Nonparametric; D019227:Tooth Apex / Q000502:physiology*; D014945:Wound Healing / Q000187:drug effects; D015034:Zinc Oxide / Q000494:pharmacology
D001881:Borates; D004338:Drug Combinations; D012117:Resins, Synthetic; D012387:Root Canal Filling Materials; C505571:Sealer Plus; D001466:Barium Sulfate; D005054:Eugenol; C038425:Fillcanal; D002126:Calcium Hydroxide; D015034:Zinc Oxide; D001729:Bismuth