title: Deep sea mining for unique biocatalysts.
abstract: In this issue of Chemistry and Biology, Ferrer and coworkers describe the discovery of five esterases from a distinct deep sea hypersaline biotope. Interestingly, one enzyme has two unique features-it contains three active centers mediating distinct esterolytic activities, and its tertiary/quaternary structure can be modulated by environmental changes.
authors.affiliation: Institute of Chemistry and Biochemistry, Department of Technical Chemistry and Biotechnology, Greifswald University, 17487 Greifswald, Germany. uwe.bornscheuer@uni-greifswald.de
authors.forename: Uwe T
authors.initials: UT
authors.lastname: Bornscheuer
mesh_terms: D001426:Bacterial Proteins; D001665:Binding Sites; D002384:Catalysis; D017753:Ecosystem; D004950:Esterases / Q000737:chemistry / Q000378:metabolism*; D008386:Marine Biology / Q000379:methods*; D011487:Protein Conformation
chemical_list: D001426:Bacterial Proteins; D004950:Esterases