Best evidence topic report. Nebulised furosemide in acute adult asthma.
A short cut review was carried out to establish whether the addition of nebulised furosemide to beta-agonist therapy improves outcomes in acute asthma. Altogether 87 papers were found using the reported search, of which two presented the best evidence to answer the clinical question. A further relevant paper was found on scanning the references of these papers. The author, date and country of origin, patient group studied, study type, relevant outcome, results, and study weaknesses of the best papers are tabulated. There is currently insufficient evidence to support the routine addition of nebulised furosemide to standard beta agonist therapy in acute asthma in adults.
Yen
Zui-Shen
ZS
Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Chen
Shyr-Chyr
SC
D000208:Acute Disease; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004630:Emergencies; D019317:Evidence-Based Medicine; D005665:Furosemide / Q000627:therapeutic use*; D006801:Humans; D009330:Nebulizers and Vaporizers
D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D005665:Furosemide