title: Pigment epithelial detachments with retinal vascular anomalous complex in age-related macular degeneration.
abstract: OBJECTIVE
  To analyze and compare the angiographic features of retinal vascular anomalous complex (RVAC) in patients with a vascularized pigment epithelial detachment (PED) secondary to age-related macular degeneration.
  
  
  METHODS
  Retrospective evaluation of fluorescein and indocyanine green angiographies of 180 patients with occult choroidal neovascularization and PED.
  
  
  RESULTS
  On indocyanine green angiography (ICGA), RVAC demonstrated as a focal hyperfluorescence in connection with retinal choroidal anastomosis was identified in 12 of the 180 eyes (6.7%) with a vascularized PED. In comparison, fluorescein angiography revealed RVAC in 6 of the 12 eyes. Associated clinical and angiographic features were intraretinal hemorrhage in all 12 eyes, cystoid macular edema in 6 eyes and preretinal hemorrhage in 4 eyes.
  
  
  CONCLUSIONS
  RVAC is better delineated on ICGA than on fluorescein angiography. In clinically suspected cases with a vascularized PED in connection with intraretinal hemorrhage and/or cystoid macular edema, ICGA should be performed to enhance management considerations.
authors.affiliation: University Eye Clinic Tübingen, Tübingen, Germany. ulrike.schneider@med.uni-tuebingen.de
authors.forename: Ulrike
authors.initials: U
authors.lastname: Schneider
authors.forename: Faik
authors.initials: F
authors.lastname: Gelisken
authors.forename: Werner
authors.initials: W
authors.lastname: Inhoffen
authors.forename: Karl Ulrich
authors.initials: KU
authors.lastname: Bartz-Schmidt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001164:Arteriovenous Fistula / Q000175:diagnosis / Q000209:etiology*; D002829:Choroid / Q000098:blood supply*; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008268:Macular Degeneration / Q000150:complications*; D008269:Macular Edema; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D012166:Retinal Hemorrhage; D012171:Retinal Vessels / Q000002:abnormalities*; D012189:Retrospective Studies
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green