Synthesis and cellular uptake of porphyrin decorated iron oxide nanoparticles-a potential candidate for bimodal anticancer therapy.
This paper reports the synthesis, characterization, and cellular uptake of the conjugate of porphyrin and iron oxide nanoparticles, which may lead to a bimodal anticancer agent that can be used in the combinational treatment of photodynamic therapy (PDT) and hyperthermia therapy (HT).
Gu
Hongwei
H
Department of Chemistry, Hong Kong University of Science & Technology, Clear Water Bay, Hong Kong, China.
Xu
Keming
K
Yang
Zhimou
Z
Chang
Chi K
CK
Xu
Bing
B
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000493:pharmacokinetics*; D005290:Ferric Compounds / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006979:Hyperthermia, Induced; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles; D010316:Particle Size; D010778:Photochemotherapy; D011166:Porphyrins / Q000138:chemical synthesis* / Q000493:pharmacokinetics*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D000970:Antineoplastic Agents; D005290:Ferric Compounds; D011166:Porphyrins; C000499:ferric oxide