Directionality of F-actin cables changes during the fission yeast cell cycle.
Longitudinal F-actin cables are thought to be important for transporting materials for polarized cell growth in fission yeast. We show that most F-actin in the cables is oriented such that the barbed end faces the nearest cell tip during interphase; however, this directionality is reversed during mitosis. These orientations of F-actin ensure proper transport of materials to growing sites during these cell-cycle stages.
Kamasaki
Tomoko
T
Division of Biology, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, 153-8902, Japan.
Arai
Ritsuko
R
Osumi
Masako
M
Mabuchi
Issei
I
D008841:Actin Cytoskeleton / Q000378:metabolism / Q000648:ultrastructure; D000199:Actins / Q000378:metabolism* / Q000648:ultrastructure; D002453:Cell Cycle / Q000502:physiology*; D049108:Cell Enlargement; D016764:Cell Polarity / Q000502:physiology*; D046529:Microscopy, Electron, Transmission; D008938:Mitosis / Q000502:physiology*; D009218:Myosins / Q000378:metabolism; D017434:Protein Structure, Tertiary / Q000502:physiology; D021381:Protein Transport / Q000502:physiology; D012568:Schizosaccharomyces / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure
D000199:Actins; D009218:Myosins