title: PoInTree: a polar and interactive phylogenetic tree.
abstract: PoInTree (Polar and Interactive Tree) is an application that allows to build, visualize and customize phylogenetic trees in a polar interactive and highly flexible view. It takes as input a FASTA file or multiple alignment formats. Phylogenetic tree calculation is based on a sequence distance method and utilizes the Neighbor Joining (NJ) algorithm. It also allows displaying precalculated trees of the major protein families based on Pfam classification. In PoInTree, nodes can be dynamically opened and closed and distances between genes are graphically represented. Tree root can be centered on a selected leaf. Text search mechanism, color-coding and labeling display are integrated. The visualizer can be connected to an Oracle database containing information on sequences and other biological data, helping to guide their interpretation within a given protein family across multiple species. The application is written in Borland Delphi and based on VCL Teechart Pro 6 graphical component (Steema software).
authors.affiliation: Nerviano Medical Sciences srl, 20014 Nerviano (MI), Italy. roberta.bosotti@nervianoms.com
authors.forename: Marco
authors.initials: M
authors.lastname: Carreras
authors.forename: Cerreras
authors.initials: C
authors.lastname: Marco
authors.forename: Eleonora
authors.initials: E
authors.lastname: Gianti
authors.forename: Gianti
authors.initials: G
authors.lastname: Eleonora
authors.forename: Luca
authors.initials: L
authors.lastname: Sartori
authors.forename: Sartori
authors.initials: S
authors.lastname: Luca
authors.forename: Simon Edward
authors.initials: SE
authors.lastname: Plyte
authors.forename: Plyte Simon
authors.initials: PS
authors.lastname: Edward
authors.forename: Antonella
authors.initials: A
authors.lastname: Isacchi
authors.forename: Isacchi
authors.initials: I
authors.lastname: Antonella
authors.forename: Roberta
authors.initials: R
authors.lastname: Bosotti
authors.forename: Bosotti
authors.initials: B
authors.lastname: Roberta
mesh_terms: D000465:Algorithms; D030562:Databases, Protein; D019143:Evolution, Molecular; D010802:Phylogeny; D011506:Proteins / Q000737:chemistry / Q000145:classification* / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins