title: [The research progress in the disease model of knock-out mouse].
abstract: The knock-out technology is an effective means in studying the gene function of organism. The disease model of gene knock-out mouse is of significance in understanding the gene function and pathogenesis of human disease. The available models of gene knock-out mouse are classified and summarized to promote the development of related research.
authors.affiliation: National Laboratory of Agrobiotechnology, China Agricultural University, Beijing100094, China.
authors.forename: Hai-fang
authors.initials: HF
authors.lastname: Yin
authors.forename: Qiu-ju
authors.initials: QJ
authors.lastname: Wang
authors.forename: Ning
authors.initials: N
authors.lastname: Li