Pictet-Spengler reactions in multiphasic supercritical carbon dioxide/CO2-expanded liquid media. In situ generation of carbamates as a strategy for reactions of amines in supercritical carbon dioxide.
Acyl-Pictet-Spengler cyclizations can be achieved in scCO2/CO2-expanded liquid media via the in situ formation of carbamate derivatives of beta-arylethylamines.
Dunetz
Joshua R
JR
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Ciccolini
Rocco P
RP
Fröling
Morgan
M
Paap
Scott M
SM
Allen
Andrew J
AJ
Holmes
Andrew B
AB
Tester
Jefferson W
JW
Danheiser
Rick L
RL