title: [A case of cutaneous vasculitis in a patient with systemic lupus erythematosus].
abstract: We present case of 55 years old female with systemic lupus erythematosus (SLE) and necrotic ulcerations in lower limbs. Etiology of this lesions was complex. In the presented case, vasculitis (microvasculitis) accompanying systemic inflammatory connective tissue disease coincides with deficiency of protein S and venous insufficiency lower limbs. It could determine necrotic type of ulcerations and location of lesions. In this case vasculitis was crucial importance and ulcerations were healed after immunosuppressive therapy. In similar cases it is often difficult to find factors responsible for development of ulcerations and it need different investigations. But detailed determine of etiopathogenesis gives guarantee therapeutic success.
authors.affiliation: Katedra i Klinika Angiologii, Nadciśnienia Tetniczego i Diabetologii AM we Wrocławiu.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Mastej
authors.forename: Maria
authors.initials: M
authors.lastname: Knapik-Kordecka
authors.forename: Rajmund
authors.initials: R
authors.lastname: Adamiec
mesh_terms: D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D017445:Skin Diseases, Vascular / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013997:Time Factors; D016896:Treatment Outcome; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D007166:Immunosuppressive Agents; D003520:Cyclophosphamide