Paraneoplastic cerebellar degeneration with fallopian tube adenocarcinoma.
BACKGROUND
Paraneoplastic cerebellar degeneration (PCD) is rarely caused by fallopian tube adenocarcinoma.


METHODS
We present a patient with PCD and fallopian tube cancer. Anti-Yo antibody, one of an anti-neuronal antibody, was positive in serum and cerebrospinal fluid. She was also positive for HLA A24, which is common in patients with PCD. Radical surgery did not significantly ameliorate her neurological impairment, although the dysarthria improved slightly.


CONCLUSIONS
This case highlights the importance of detecting the underlying malignancy in patients with subacute neurological impairment and shows that fallopian tube cancer can potentially cause PCD.
Tanaka
Yudai
Y
Department of Obstetrics and Gynecology, Yamato Municipal Hospital, Kanagawa, Japan.
Suzuki
Nao
N
Takao
Masaki
M
Ichikawa
Akiko
A
Susumu
Nobuyuki
N
Aoki
Daisuke
D
D000230:Adenocarcinoma / Q000150:complications* / Q000276:immunology / Q000601:surgery; D005185:Fallopian Tube Neoplasms / Q000150:complications* / Q000276:immunology / Q000601:surgery; D005260:Female; D015234:HLA-A Antigens / Q000097:blood; D059871:HLA-A24 Antigen; D006801:Humans; D008875:Middle Aged; D020362:Paraneoplastic Cerebellar Degeneration / Q000209:etiology* / Q000276:immunology
D015234:HLA-A Antigens; D059871:HLA-A24 Antigen