Radical-carbanion cyclo-coupling in armed aromatics: overriding steric hindrance to ring closure.
Omega-(2-Halophenyl)alkyl-2-oxazolines were prepared and reacted via base promoted intramolecular coupling of radical with carbanionic centres to yield 1-phenyl-1-oxazolino-indan and -tetralin derivatives containing quaternary C-atoms.
Roydhouse
Mark D
MD
University of St. Andrews, School of Chemistry, EaStCHEM, St. Andrews, Fife, KY16 9ST, UK.
Walton
John C
JC