title: Clinical observation on 96 cases of primary osteoporosis treated with kidney-tonifying and bone-strengthening mixture.
abstract: OBJECTIVE
  To objectively evaluate the therapeutic effect and safety of Mixture for Nourishing Kidney and Strengthening Bone.
  
  
  METHODS
  Among 160 cases of osteoporosis under clinical observation, 96 patients in the treatment group were treated with Mixture for Nourishing Kidney and Strengthening Bone, 32 patients in the control group were given Shen Gu Capsule and 32 patients in the blank group were given no drug in half a year. Observation and determination were conducted on bone mineral density (BMD), clinical symptoms, bone gla protein (BGP), pyridinoline (PYD), estradiol (E2), testosterone (T), blood urea nitrogen (BUN), transaminase and routine test on blood and urine.
  
  
  RESULTS
  The comprehensive effect in the treatment group was remarkably superior to that in the control group.
  
  
  CONCLUSIONS
  The safe and reliable Chinese drug can enhance BMD, promote osteogenesis and inhibit bone absorption, hence treating osteoporosis with marked effect.
authors.affiliation: Xuanwu Hospital Affiliated to Capital Medical University, Beijing 100053, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Mingyue
authors.forename: Gong
authors.initials: G
authors.lastname: Ling
authors.forename: Xia
authors.initials: X
authors.lastname: Bei
authors.forename: Cao
authors.initials: C
authors.lastname: Junqing
authors.forename: Zhou
authors.initials: Z
authors.lastname: Peiqing
authors.forename: Hu
authors.initials: H
authors.lastname: Jie
mesh_terms: D000368:Aged; D000596:Amino Acids / Q000097:blood; D015519:Bone Density; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood; D010024:Osteoporosis / Q000188:drug therapy*; D008517:Phytotherapy
chemical_list: D000596:Amino Acids; D004365:Drugs, Chinese Herbal; D015675:Osteocalcin; C015484:pyridinoline