Feasibility and outcome of HCV treatment in a Canadian federal prison population.
We assessed feasibility and outcome of hepatitis C virus (HCV) treatment in male correctional inmates in British Columbia, Canada. We reviewed the medical charts of 114 treated inmates; 80 had complete data for treatment outcome. Approximately 4 of 5 inmates completed treatment (78.8%); 66.3% achieved sustained virological response. Those who completed treatment, those with injection drug use as a risk factor, and those with genotypes 2 and 3 were significantly more likely to achieve sustained virological response. HCV treatment in correctional inmates is feasible and effective.
Farley
John
J
University of British Columbia, Vancouver, BC, Canada.
Vasdev
Shawn
S
Fischer
Benedikt
B
Haydon
Emma
E
Rehm
Jürgen
J
Farley
Theresa A
TA
D000328:Adult; D001955:British Columbia / Q000453:epidemiology; D004279:DNA, Viral / Q000235:genetics; D004338:Drug Combinations; D005240:Feasibility Studies; D035082:Federal Government; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics; D006526:Hepatitis C / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D008875:Middle Aged; D015999:Multivariate Analysis; D009294:Narcotics / Q000627:therapeutic use; D015995:Prevalence; D011330:Prisons / Q000458:organization & administration*; D015397:Program Evaluation; D012189:Retrospective Studies; D012254:Ribavirin / Q000627:therapeutic use*; D012307:Risk Factors; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000188:drug therapy; D016896:Treatment Outcome
D004279:DNA, Viral; D004338:Drug Combinations; D016898:Interferon-alpha; D009294:Narcotics; C118689:Rebetron; D012254:Ribavirin; D008691:Methadone