title: Radical-mediated diastereoselective construction of a chiral synthon for synthesis of dolabellanes.
abstract: [reaction: see text] A useful trans-substituted multifunctional cyclopentane with a chiral quaternary center was selectively synthesized by free radical Michael addition to the (Z)-propionate or -malonate derivatives. The stereoselectivity could be reversed by changing the configuration of the double bond.
authors.affiliation: State Key Laboratory of Bio-organic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Zhu
authors.forename: K Y
authors.initials: KY
authors.lastname: Fan
authors.forename: H W
authors.initials: HW
authors.lastname: Ma
authors.forename: L X
authors.initials: LX
authors.lastname: Qiao
authors.forename: Y L
authors.initials: YL
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Wu