Highly selective palladium-catalyzed Heck reactions of aryl bromides with cycloalkenes.
[reaction: see text] The influence of palladium catalysts and reaction conditions on the selectivity of Heck reactions of aryl bromides with cyclohexene and cyclopentene has been investigated. It is shown that the addition of DMSO as a cosolvent leads to improved selectivities of nonconjugated aryl olefins. On the other hand, high selectivities for conjugated arylcyclopentenes have been obtained with the catalytic system DMA/Na2CO3/Pd2(dba)3 x dba/PCy3.
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Anorganisch-chemisches Institut, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching, Germany.
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Beller
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