title: Acute renal failure due to cast nephropathy in nonsecretory myeloma: a case report and review of the literature.
abstract: Multiple myeloma is characterized by marrow plamacytsois, M spike in serum or urine electrophoresis and skeletal lytic lesions. The M spike may be absent in rare instances. We describe a case of myeloma cast nephropathy with acute renal failure who did not exhibit an M spike. lambda-chain staining was documented on immunoperoxidase, suggesting paraprotein-related tubular damage.
authors.affiliation: Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: S Karthik
authors.initials: SK
authors.lastname: Kumar
authors.forename: Preet M
authors.initials: PM
authors.lastname: Sohal
authors.forename: Harbir S
authors.initials: HS
authors.lastname: Kohli
authors.forename: Kamal
authors.initials: K
authors.lastname: Sud
authors.forename: Krishan L
authors.initials: KL
authors.lastname: Gupta
authors.forename: Kusum
authors.initials: K
authors.lastname: Joshi
authors.forename: Vinay
authors.initials: V
authors.lastname: Sakhuja
authors.forename: Vivekanand
authors.initials: V
authors.lastname: Jha
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D007684:Kidney Tubules / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D010265:Paraproteinemias / Q000150:complications