The association between prenatal and or post natal growth disorder and lipid profile in adolescents aged 12 - 15 years old in Tanjungsari Subdistrict, Sumedang, West Java.
OBJECTIVE
to investigate association between growth disorders in pre and post natal period and abnormal lipid profile in adolescents aged 12 -15 years old in Tanjungsari population.


METHODS
a cohort study was conducted in 3350 children who were born in 1988-1990 in Tanjungsari Subdistrict, Sumedang, West Java. A complete anthropometric data since their birth were collected from October 2002-February 2003.


METHODS
Children who had birth weight in the range of +/- 3 of standard deviation (SD). Post natal growth disorder based on Z score of height according to age group and height changes at the age of 0-12 months and 12-36 months. SGA criteria were determined based on cross tabulation between weight and birth length at birth. Study subjects were divided into control group, groups of pre natal, post natal and pre-postnatal growth disorder. All subjects were checked for lipid profiles. Statistical calculation used analysis of variance, t test and logistic regression. 312 subjects were included in this study, 73 were in control group, 90 subjects in postnatal, 96 subjects were in pre natal and 53 subjects were in pre-post natal growth disorder group.


RESULTS
this study has not shown significant difference in risk factor of having abnormal lipid profile between normal control group and growth disorder group except for those in prenatal growth disorder group with RR = 2.375 (p = 0.014).


CONCLUSIONS
the post natal growth disorder had not influenced lipid profile in adolescents with SGA. Recent BMI was an additional risk factor for pre-post natal growth disorder group.
Sukesi
Lilik
L
Cardio-Cerebrovascular Diseases Working Group Unit, Frontier For Health Foundation, Department of Internal Medicine, Faculty of Medicine, Padjajaran University / Hasan Sadikin Hospital, Bandung.
Sjukrudin
E Suardi
ES
Purnomowati
A
A
Widjaja
G
G
Fadlyana
E
E
Alisjahbana
B
B
Alisjahbana
A
A
D000293:Adolescent; D001724:Birth Weight; D015992:Body Mass Index; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D047109:Fetal Development; D006130:Growth Disorders / Q000150:complications*; D006801:Humans; D007214:Indonesia; D007223:Infant; D007231:Infant, Newborn; D008055:Lipids / Q000097:blood*; D008297:Male; D012307:Risk Factors
D008055:Lipids