[Interferon-gamma, idiotypic and anti-idiotypic autoantibodies in pyodermias of various etiology].
Sera of 80 patients with pyodermias of varius etiology were analysed for interferon-gamma (IF-gamma), antiinterferon autoantibodies (IF-a-AB), corresponding antiidiotypic antibodies (IF-AIAB) and the ratio IF-a-AB/IF-AIAB using ELISA assay. There was no correlation between serum IF-gamma and IF-a-AB. Progression of this disease was characterized by an increase of serum IF-a-AB and a decrease of IF-AIAB. Prolonged duration of this disease also caused the decrease of serum anti IF-a-AB and IF-AIAB. The ratio of IF-a-AB/IF-AIAB increased with severity and duration of this disease.
Morozov
S G
SG
Volkova
E N
EN
Gnedenko
B B
BB
Protsenko
B B
BB
Fediukin
V S
VS
D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D001323:Autoantibodies / Q000097:blood*; D002846:Chromatography, Affinity; D006801:Humans; D007124:Immunoenzyme Techniques; D007371:Interferon-gamma / Q000097:blood*; D011711:Pyoderma / Q000097:blood / Q000209:etiology / Q000276:immunology*; D012720:Severity of Illness Index
D000888:Antibodies, Anti-Idiotypic; D001323:Autoantibodies; D007371:Interferon-gamma