title: Topical antiseptics in healthcare.
abstract: Topical antiseptics are essential for infection control. Antiseptic formulations employ a variety of mechanisms, act at various rates and persistence intervals, demonstrate various levels of toxicity, and are more or less likely to trigger resistance. The desired characteristics are considered when selecting antiseptics for hand washing, surgical scrubbing, and patient preoperative skin preparation. The selection process requires evidence of product safety and efficacy. This article explores currently available topical antimicrobial agents used in medical settings.
authors.affiliation: Food and Drug Administration, Rockville, MD, USA. jacksonm@cder.fda.gov
authors.forename: Michelle M
authors.initials: MM
authors.lastname: Jackson
mesh_terms: D000891:Anti-Infective Agents, Local / Q000145:classification; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006262:Health; D006801:Humans; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000891:Anti-Infective Agents, Local