title: The "third eye"-- a new concept of trans-differentiation of pineal gland into median eye in amphibian tadpoles of Bufo melanostictus.
abstract: Median third eye was found to develop from transplanted pineal gland of external gill stage tadpoles in the recipient 5 toe stage tadpoles of Bufo melanostictus. Pineal gland along with a bit part of brain tissue of the donor external gill stage tadpole was cut out and transplanted into a pit made between two lateral eyes of 5 toe stage recipient tadpoles. Half of the operated tadpoles were treated with vitamin A (15 IU/ml.) for 15 days. Median "third eye" was found to develop in the both untreated and vitamin A treated tadpoles. However, vitamin A increased the percentage of the development of median eyes. Morphological and histological study revealed that newly transformed median eyes were similar to that of normal functional eyes. A stalk like structure developed which connects the median eye to the brain. The median third eye could not develop when pineal gland of 5 toe stage mature tadpole was transplanted into the tadpole of the same age.
authors.affiliation: Department of Zoology, Dungar College, Bikaner 334001, India. op_jangir2003@yahoo.com
authors.forename: O P
authors.initials: OP
authors.lastname: Jangir
authors.forename: P
authors.initials: P
authors.lastname: Suthar
authors.forename: D V S
authors.initials: DV
authors.lastname: Shekhawat
authors.forename: P
authors.initials: P
authors.lastname: Acharya
authors.forename: K K
authors.initials: KK
authors.lastname: Swami
authors.forename: Manshi
authors.initials: M
authors.lastname: Sharma
mesh_terms: D000818:Animals; D002025:Bufonidae / Q000254:growth & development*; D005123:Eye / Q000187:drug effects / Q000196:embryology; D007814:Larva / Q000254:growth & development; D009024:Morphogenesis / Q000187:drug effects; D010870:Pineal Gland / Q000187:drug effects / Q000196:embryology; D014801:Vitamin A / Q000494:pharmacology
chemical_list: D014801:Vitamin A