[Prevalence of anti-Chlamydophila pneumoniae antibodies in patients with intrinsic asthma].
Chlamydophila pneumoniae is a respiratory pathogen which has been involved in the pathogenesis of a number of chronic diseases. We studied the association between IgG antibodies against C. pneumoniae and intrinsic asthma in adults. C. pneumoniae IgG serum titers were determined by enzymatic immunoassay in 55 adult patients and 87 healthy controls. A significant association was found between anti-C. pneumoniae antibodies and intrinsic asthma, as compared to the control group (23.6% vs. 10.3%, p <0.05). C. pneumoniae may therefore be involved in the origin or in exacerbations of intrinsic asthma.
Rodríguez Polo
J A
JA
Departamento de Microbiología, Hospital Universitario de Salamanca, Salamanca, Spain.
Muñoz
F J
FJ
Muñoz Bellido
J L
JL
García Rodríguez
J A
JA
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D001249:Asthma / Q000276:immunology / Q000382:microbiology*; D023521:Chlamydophila Infections / Q000503:physiopathology*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D015995:Prevalence
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G