title: Fatigue at long-term follow-up in young adults with cerebral infarction.
abstract: BACKGROUND
  To study the impact of fatigue in young ischaemic stroke patients.
  
  
  METHODS
  The Fatigue Severity Scale score was obtained in 192 patients (mean time 6.0 years after the stroke) and 212 controls.
  
  
  RESULTS
  Fatigue was associated with cerebral infarction in a multivariate analysis of patients and controls (p = 0.002). Fatigue was independently associated with unfavourable functional outcome (p = 0.001), depression (p < 0.001), and basilar artery infarction through interaction with the modified Rankin Scale score (p = 0.047) in patients.
  
  
  CONCLUSIONS
  Fatigue is frequent in young adults with cerebral infarction. Stroke-related factors independently associated with fatigue include functional outcome. Stroke location may influence fatigue.
authors.affiliation: Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway. halvor.naess@haukeland.no
authors.forename: Halvor
authors.initials: H
authors.lastname: Naess
authors.forename: Harald I
authors.initials: HI
authors.lastname: Nyland
authors.forename: Lars
authors.initials: L
authors.lastname: Thomassen
authors.forename: Jan
authors.initials: J
authors.lastname: Aarseth
authors.forename: Kjell-Morten
authors.initials: KM
authors.lastname: Myhr
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D002544:Cerebral Infarction / Q000150:complications* / Q000523:psychology; D003863:Depression / Q000209:etiology / Q000523:psychology; D004185:Disability Evaluation; D005221:Fatigue / Q000209:etiology* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011584:Psychology; D014715:Vertebrobasilar Insufficiency / Q000150:complications / Q000523:psychology