title: [Recovery of sickle cell disease ischemic maculopathy after erythropheresis: a clinical case study].
abstract: The authors report a case of a young patient with a recent decrease in unilateral vision. He had homozygote sickle cell disease with multiple general complications. Fundus examination was normal apart from a mild alteration of the macular reflect in the left eye, but fluorescein angiography showed multiple arteriolar macular occlusions, explaining the decrease in vision in the left eye. After erythropheresis, vision acuity improved and fluorescein angiography showed reperfusion. This case suggests that transfusional exchange may improve acute macular ischemia secondary to sickle cell disease.
authors.affiliation: Service d'Ophtalmologie, CHU du Kremlin-Bicêtre, Le Kremlin-Bicêtre, Paris.
authors.forename: N
authors.initials: N
authors.lastname: Leveziel
authors.forename: O
authors.initials: O
authors.lastname: Kirsch
authors.forename: M
authors.initials: M
authors.lastname: Lautier-Frau
authors.forename: F
authors.initials: F
authors.lastname: Driss
authors.forename: H
authors.initials: H
authors.lastname: Offret
authors.forename: M
authors.initials: M
authors.lastname: Labetoulle
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D001803:Blood Transfusion; D004920:Erythropoiesis; D005451:Fluorescein Angiography; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D015349:Vision, Monocular