[Subacute uveomeningoencephalitis as the presenting symptom of acute infection by the human immunodeficiency virus].
BACKGROUND
The uveo-meningitic syndrome, or the combination of chronic or recurrent meningitis and acute uveitis, has a specific differential diagnosis. This syndrome can be the clinical debut of systemic disorders, vasculophathies, connective tissue disorders and inmuno-mediated diseases. In patients with AIDS, the syndrome often appears in relation with an opportunist concomitant infection of the central nervous system (CNS).


METHODS
We present one case of subacute uveo-meningitic syndrome as symptomatic presentation of a early infection of HIV. The patient was a man, 37 years-old. He was inmunocompetent and did not know his seropositivity for HIV type 1. We relate the results of the neurologic examination and complementary tests. Only serologic test for HIV type 1 and detection of IgG anti-HIV in cerebrospinal fluid were positives.


CONCLUSIONS
In patients HIV-positive the ocular infection, usually a posterior uveitis, appears together with systemic disorders or central nervous infections. In other hand, the cause of meningitic infection depends on grade of immunocompromise. Aseptic meningitis, for early stages of the disease, is usually no symptomatic. After, opportunist infections or neoplasic infiltration of CNS can be cause of meningoencephalitis. In this patient, the early infection of HIV causes an subacute uveomeningoencephalitis. Early infection of HIV increases the possibilities of aetiological diagnosis of uveomeningitic syndrome.
Pascual-Lozano
A M
AM
Servicio de Neurología, Hospital Clínico Universitario de Valencia, Valencia, Spain. med004201@saludalia.com
Salvador-Aliaga
A
A
Coret-Ferrer
F
F
Láinez-Andrés
J M
JM
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000328:Adult; D015483:HIV Antibodies / Q000134:cerebrospinal fluid; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006679:HIV Seropositivity; D015497:HIV-1; D006801:Humans; D008297:Male; D013577:Syndrome; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis / Q000209:etiology*
D015483:HIV Antibodies