[Pathophysiology of interstitial lung disease].
Chronic interstitial lung disease (ILD) groups a number of diseases with the common feature of radiological pulmonary infiltration, typical functional syndrome, and diffuse involvement of the deep pulmonary parenchyma identified histologically. Correlations between histological and radiological findings have enabled progress in both fields, leading to better interpretation of the radiological findings and optimizing the etiological diagnosis. Besides the signs themselves, their distribution in relation to the normal lung structures is highly contributive. Function tests can be used to quantify the impact on the respiratory system and assess the effect of treatment. Evidence-based criteria will progressively replace the consensual criteria enabling more effective evaluation of treatment in difficult pathological conditions such as idiopathic pulmonary fibrosis.
Duperron
Florence
F
Service de Pneumologie, Hôpital Avicenne, 125, route de Stalingrad, 93009 Bobigny, et UFR SMBH, Université Paris 13, Bobigny.
Velea
Valeria
V
Ioos
Vincent
V
Brauner
Michel
M
Lamberto
Christine
C
Valeyre
Dominique
D
D006801:Humans; D017563:Lung Diseases, Interstitial / Q000209:etiology / Q000503:physiopathology*