title: Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima.
abstract: Prorocentin (1), isolated from an okadaic acid-producing organism, Prorocentrum lima, possessed all-trans trienes, an epoxide, as well as the 6/6/6-trans-fused/spiro-linked polyether ring moieties. The unique structure supports the proposed cyclization mechanism, polyene formation, epoxidation, and cyclization, of marine polyether toxins. The relative stereostructure was determined on the basis of spectral data. [structure: see text]
authors.affiliation: National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan. cklu@nmmba.gov.tw
authors.forename: Chung-Kuang
authors.initials: CK
authors.lastname: Lu
authors.forename: Hong-Nong
authors.initials: HN
authors.lastname: Chou
authors.forename: Ching-Kuo
authors.initials: CK
authors.lastname: Lee
authors.forename: Tzong-Huei
authors.initials: TH
authors.lastname: Lee
mesh_terms: D000818:Animals; D003500:Cyclization; D004141:Dinoflagellida / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019319:Okadaic Acid / Q000378:metabolism
chemical_list: D005663:Furans; D018942:Macrolides; C511474:prorocentin; D019319:Okadaic Acid