[Diagnostic difficulties in identification of Haemophilus influenzae colonising the nasopharynx of children].
The frequency of capsulated or non-capsulated Haemophilus influenzae strains colonisation among children attending day-care centres or orphanages has been studied. Detection of capsulated or non-capsulated H. influenzae strains has been compared for agglutination test and PCR. Misdiagnosing of H. influenzae serotype with agglutination found in the study suggest that the frequency of Hib strains colonizing the nasopharynx might be lower that previously evaluated. Due to perspectives of the wider use of Hib Immunisation in the future, more efficient diagnosis scheme for identification/differentiation of capsulated and non-capsulated H. influenzae strain should be undertaken.
Augustynowicz
Ewa
E
Zakład Badania Surowic i Szczepionek PZH w Warszawie.
Szenborn
Leszek
L
Banyś
Dorota
D
Nowaczek
Aneta
A
Gzyl
Anna
A
Slusarczyk
Janusz
J
D002353:Carrier State / Q000453:epidemiology*; D002648:Child; D002656:Child Day Care Centers / Q000706:statistics & numerical data; D003937:Diagnosis, Differential; D006192:Haemophilus Infections / Q000382:microbiology*; D018073:Haemophilus Vaccines / Q000627:therapeutic use; D006193:Haemophilus influenzae / Q000145:classification* / Q000302:isolation & purification*; D006801:Humans; D009305:Nasopharynx / Q000382:microbiology*; D019372:Orphanages / Q000706:statistics & numerical data; D011044:Poland / Q000453:epidemiology; D016133:Polymerase Chain Reaction
D018073:Haemophilus Vaccines