title: Effect of alendronate on bone mineral density in Puerto Rican males with osteoporosis.
abstract: Osteoporosis in men was not recognized as a major health problem until recently, and increased research in this area resulted in the approval of alendronate for the treatment of osteoporosis in men at the beginning of this decade. Low bone mineral density (BMD) has been demonstrated to be a strong predictor of fracture in men as it is in women. The causes of osteoporosis in men are variable and can be classified as primary or secondary. The aim of these report is to present the response of BMD in 10 Puerto Rican men with secondary causes of osteoporosis treated with alendronate. A significant increase of BMD in spine, total hip, trochanter and intertrochanteric regions were noted. A non-significant increase in femoral neck was observed.
authors.affiliation: Endocrinology and Metabolism Section, Department of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Martinó
authors.forename: Jessica
authors.initials: J
authors.lastname: Rosa
authors.forename: Josué
authors.initials: J
authors.lastname: Guzmán
authors.forename: Margarita
authors.initials: M
authors.lastname: Ramírez
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D019386:Alendronate / Q000627:therapeutic use*; D015519:Bone Density / Q000187:drug effects*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis / Q000188:drug therapy* / Q000208:ethnology; D011647:Puerto Rico / Q000208:ethnology; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D019386:Alendronate