A total synthesis of guanacastepene C.
A total synthesis of the structure corresponding to the novel tricyclic diterpene guanacastepene C has been realized in which a Knoevenagel cyclization serves as a key step to annulate the six-membered C-ring on a stereochemically secured bicyclic hydroazulene precursor.
Mehta
Goverdhan
G
Department of Organic Chemistry, Indian Institute of Science, Bangalore, India. gm@orgchem.iisc.ernet.in
Pallavi
Kotapalli
K
Umarye
Jayant D
JD
D001643:Bridged Bicyclo Compounds / Q000737:chemistry; D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis; D005658:Fungi / Q000737:chemistry; D007202:Indicators and Reagents
D001643:Bridged Bicyclo Compounds; D004224:Diterpenes; D007202:Indicators and Reagents; C409194:guanacastepene