A simple spectrophotometric method for determination of sodium diclofenac in pharmaceutical formulations.
A new, simple, rapid and accurate spectrophotometric method is proposed for determination of sodium diclofenac (SD) in pharmaceutical preparations based on its reaction with concentrated nitric acid (63% w/v). The reaction product is a yellowish compound with maximum absorbance at 380 nm. The corresponding calibration curve is linear over the range of 1-30 mg l(-1), while the limit of detection is 0.46 mg l(-1).
Matin
A A
AA
Food and Chemical Analyses Research Center, Jahad-e-Daneshgahi, Urmia, Iran.
Farajzadeh
M A
MA
Jouyban
A
A
D004008:Diclofenac / Q000032:analysis* / Q000737:chemistry; D017942:Nitric Acid / Q000737:chemistry; D012996:Solutions; D013053:Spectrophotometry; D013488:Suppositories; D013607:Tablets
D012996:Solutions; D013488:Suppositories; D013607:Tablets; D004008:Diclofenac; D017942:Nitric Acid