Structural characterization of a series of 10-carbon sugar derivatives by electrospray-ionization MSn mass spectrometry.
Electrospray-ionization MSn mass spectrometry (ESI-MSn) with low-energy, collision-induced dissociation (CID) was used to establish the fragmentation behavior of sodium ion adducts of higher-carbon amino spiro-sugar derivatives. Their fragmentation pathways are proposed on the basis of the MSn studies and deuteration experiments. Some of the rings of these derivatives opened under the conditions of electrospray ionization. Novel fragmentations were observed and their mechanisms are proposed. This study demonstrates the power of modern mass spectrometry for rapid elucidation of the structure of higher-carbon sugar derivatives.
Zou
Da-Peng
DP
Department of Chemistry, Zhengzhou University, Zhengzhou 450052, PR China.
Cao
Shu-Xia
SX
Xu
Wei-Chao
WC
Liu
Hong-Min
HM
D000606:Amino Sugars / Q000737:chemistry*; D003903:Deuterium; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013141:Spiro Compounds / Q000737:chemistry*
D000606:Amino Sugars; D013141:Spiro Compounds; D003903:Deuterium