ROCPLOT: a generic software tool for ROC analysis and the validation of predictive methods.
Receiver operating characteristic (ROC) analysis is a powerful and widely used technique for assessing predictive methods, yet there are no generic, open-source software tools for this that are freely available. Our ROCPLOT program performs ROC analysis on one or more files of search results (hits) and generates the following: (i) ROC values, giving a convenient numerical measure of method sensitivity and specificity; (ii) ROC plots graphically displaying sensitivity and specificity; (iii) classification plots to aid interpretation of the ROC plots and values; and (iv) a bar chart of the distribution of ROC values. ROCPLOT is generic and flexible: data in multiple hits files can be processed in series or parallel, allowing the results of multiple predictions to be viewed side-by-side or combined.


BACKGROUND
ROCPLOT is freely available for download as part of the European Molecular Biology Open Software Suite, EMBOSS (http://emboss.sourceforge.net/apps/rocplot.html).
Ison
Jon C
JC
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK. jison@rfcgr.mrc.ac.uk
Blades
Matthew J
MJ
D003196:Computer Graphics; D003627:Data Interpretation, Statistical; D008954:Models, Biological; D015233:Models, Statistical; D012372:ROC Curve; D012984:Software; D014584:User-Computer Interface