title: Trends of prevalence and pathological spectrum of head and neck cancers in North India.
abstract: BACKGROUND
  Head and neck neoplasia constitute one of the commonest cancers in India. Use of smokeless tobacco (Pan masala, Zarda etc.) is on the increase in North India, especially in Uttar Pradesh, and is responsible for the large majority of these tumours.
  
  
  OBJECTIVE
  To assess the patients' characteristics, yearly prevalence and histopathological subtypes of the head and neck neoplasia (excluding oral cavity) in Allahabad and surrounding regions.
  
  
  METHODS
  A retrospective study of 11 years from 1990 to 2000 was designed. Data was collected year-wise using the tumor registry data.
  
  
  METHODS
  All biopsies submitted for histopathology to the Pathology department were reviewed and analyzed for demographic data, site and diagnosis.
  
  
  METHODS
  The Kolmogorov-Smirnov Two-Sample Test was utilized to determine whether two distributions are the same.
  
  
  RESULTS
  A total of 40559 biopsies were examined in the department, of which, lesions of the head and neck region, excluding the oral cavity, constituted 694 biopsies (409 males and 285 females). One hundred and forty-four malignant lesions were reported, 114 being males and 30 females. A comparison of the age-specific prevalence rates of cancer during the study period showed that the prevalence was highest in patients belonging to the 50-59 years age group and squamous cell carcinoma Grade II was the most prevalent type. On an average, 58 new biopsies per annum were received.
  
  
  CONCLUSIONS
  Properly structured site-specific data like this can augment the National Cancer Registry Programme and is an essential indicator for the magnitude and the pattern of the cancer problem in India.
authors.affiliation: Department of Pathology, Moti Lal Nehru Medical College, Allahabad, India.
authors.forename: Ravi
authors.initials: R
authors.lastname: Mehrotra
authors.forename: Mamata
authors.initials: M
authors.lastname: Singh
authors.forename: Raj Kishore
authors.initials: RK
authors.lastname: Gupta
authors.forename: Manish
authors.initials: M
authors.lastname: Singh
authors.forename: Anil K
authors.initials: AK
authors.lastname: Kapoor
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006258:Head and Neck Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012042:Registries; D012189:Retrospective Studies