Indocyanine green angiography of juvenile X-linked retinoschisis.
OBJECTIVE
In juvenile X-linked retinoschisis (XLRS), fluorescein angiography is usually unremarkable and contributes poorly to the diagnosis. However, indocyanine green (ICG) angiography features in eyes that are affected with XLRS were not yet described.


METHODS
Retrospective observational case series.


METHODS
A complete ophthalmologic examination that included ICG angiography was performed on three unrelated male patients (six eyes) who were 15, 22, and 48 years old.


RESULTS
A distinct hyperfluorescent stellate pattern in the macular area that was associated with radial lines of hypofluorescence that were centered on the foveola was observed on the early phase of ICG examination (six of six eyes). This feature disappeared on the late phase of ICG examination.


CONCLUSIONS
On these six XLRS eyes, early phases of ICG examination revealed an unusual radial aspect on the macula. This finding suggests that ICG angiography may be useful for the diagnosis of XLRS.
Souied
Eric H
EH
Clinique Ophtalmologique Universitaire de Créteil, 40 Avenue de Verdun, 94010 Créteil, France. eric.souied@chicreteil.fr
Goritsa
Anna
A
Querques
Giuseppe
G
Coscas
Gabriel
G
Soubrane
Gisele
G
D000293:Adolescent; D000328:Adult; D004396:Coloring Agents; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D041441:Retinoschisis / Q000175:diagnosis*; D012189:Retrospective Studies
D004396:Coloring Agents; D007208:Indocyanine Green