[Glomerular disease and living donor kidney transplantation].
Glomerular diseases are an important and frequent cause of renal transplant graft loss in the mid-long term, mainly due to primary renal disease recurrence. Glomerular diseases have particular connotations in living donor kidney transplantation, due to the risk of primary disease recurrence and subsequent graft loss, and also the risk of development of glomerular disease related donors have for their genetic similitude. The incidence of glomerular disease recurrence after transplantation varies with type, being especially frequent in IgA nephropathy and type II membranous proliferative glomerulopathy. The difference between histological and clinical recurrence should always be established, being much more frequent the first. Renal biopsy is the essential diagnostic test to detect and confirm the existence of glomerular disease after transplant, with immunofluorescence study being necessary to determine the type of glomerular disease.
Guerra
Rita
R
Servicio de Neurología, Hospital Universitario Insular de Las Palmas de Gran Canaria, España.
Rodríguez
Alejandra
A
Campistol
Josep M
JM
D005921:Glomerulonephritis / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D012008:Recurrence