Acute renal failure due to cast nephropathy in nonsecretory myeloma: a case report and review of the literature.
Multiple myeloma is characterized by marrow plamacytsois, M spike in serum or urine electrophoresis and skeletal lytic lesions. The M spike may be absent in rare instances. We describe a case of myeloma cast nephropathy with acute renal failure who did not exhibit an M spike. lambda-chain staining was documented on immunoperoxidase, suggesting paraprotein-related tubular damage.
Kumar
S Karthik
SK
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sohal
Preet M
PM
Kohli
Harbir S
HS
Sud
Kamal
K
Gupta
Krishan L
KL
Joshi
Kusum
K
Sakhuja
Vinay
V
Jha
Vivekanand
V
D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D007684:Kidney Tubules / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D010265:Paraproteinemias / Q000150:complications