American Association for Cancer Research--90th annual meeting. 10-14 April 1999, Philadelphia, PA, USA.
A major focus of this year's American Association for Cancer Research (AACR) meeting was the microenvironment of the tumor and tumor angiogenesis, as well as the development of drugs that affect tumor growth by use of extratumoral targets. Other areas of interest were advances in chemoprevention, cancer vaccines, gene therapy approaches and drug-resistance features. As before, many novel compounds affecting tumor cells were introduced, either being analogs of standard cytostatic agents or directed against new cellular targets. Mechanisms of action were further unraveled and emphasis was put on the various signals within a tumor cell to enter cell death through apoptosis. Molecular biology technology was dedicated to the development of tests to measure gene expression in small tissue samples.
Boven
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Department of Medical Oncology, Academic Hospital, Vrije Universiteit, De Boelelaan 1117, NL-1081 HV Amsterdam, The Netherlands. e.boven.oncol@med.vu.nl