PISA method for assessment of mitral regurgitation in children.
OBJECTIVE
The purpose of this study was to determine the feasibility and significance of the proximal isovelocity surface area (PISA) method in children with rheumatic mitral regurgitation (MR).


METHODS
Thirty-one children (mean age 12.3+/-3.1 years), with chronic MR, were evaluated by semiquantitative and quantitative Doppler, quantitative two-dimensional echocardiography and the PISA methods. Also, we compared the effective regurgitant orifice area, regurgitation volume and systolic left ventricular functions in mild-moderate and severe MR.


RESULTS
There were no statistically significant differences in the regurgitant orifice area and regurgitant volume values obtained by the PISA method and the quantitative Doppler (p>0.05) but they were different from the same values obtained by two dimensional echocardiography (p<0.05). There were excellent correlations between the regurgitant orifice area, regurgitant volume and the radius of the proximal flow convergence hemisphere (r=0.882, r=0.925, r=0.880; p<0.05). We found a very good correlation between the regurgitant orifice area obtained by the PISA and left ventricular end-diastolic diameters, the ratio of the jet/left atrial area, grading with color Doppler imaging (r=0.763, r=0.745, r=0.618; p<0.05).


CONCLUSIONS
It is concluded that MR can be accurately predicted in children by using the PISA method as like as the Doppler method.
Başpinar
Osman
O
Department of Pediatric Cardiology, Gaziantep University Faculty of Medicine, 27310 Gaziantep, Turkey. osmanbaspinar@hotmail.com
Karaaslan
Sevim
S
Oran
Bülent
B
D000293:Adolescent; D002648:Child; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012720:Severity of Illness Index