title: Wavefront-guided laser in situ keratomileusis using the WaveScan system for correction of low to moderate myopia with astigmatism: 6-month results in 277 eyes.
abstract: OBJECTIVE
  To assess the safety and effectiveness of wavefront guided LASIK surgery using the Visx WaveScan system for correction of low to moderate myopia with astigmatism.
  
  
  METHODS
  Multicenter study at 6 sites in the United States.
  
  
  METHODS
  In this prospective nonrandomized clinical trial, treatments were performed at 6 sites in the United States using the WaveScan (CustomVue) guided excimer laser. A total of 351 eyes were enrolled, and 277 eyes were analyzed at 6 months.
  
  
  RESULTS
  At 6 months, 94% of eyes achieved an uncorrected visual acuity (UCVA) of 20/20 or better and 74% achieved a UCVA of 20/16 or better. Sixty-nine percent of eyes had the same or better postoperative UCVA than their preoperative best spectacle-corrected visual acuity (BSCVA). Ninety percent of eyes were within +/-0.5 diopter of intended correction. No eye lost more than 1 line of BSCVA. Total higher-order root-mean square (RMS), coma, and spherical aberration values were stable (P<.05).
  
  
  CONCLUSIONS
  The data support the safety and effectiveness of the WaveScan-guided customized laser ablation using the Visx Star S4 system for correction of low to moderate myopia with astigmatism.
authors.affiliation: Refractive Surgery Center, The Wilmer Eye Institute, The Johns Hopkins University (Jabbur), Baltimore, Maryland, USA. nsjabbur@jhmi.edu
authors.forename: Nada S
authors.initials: NS
authors.lastname: Jabbur
authors.forename: Colman
authors.initials: C
authors.lastname: Kraff
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D015350:Contrast Sensitivity; D003319:Corneal Stroma / Q000601:surgery; D019781:Corneal Topography / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D017060:Patient Satisfaction; D011446:Prospective Studies; D012029:Refraction, Ocular; D012449:Safety; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity