[Motor cortex by real-time imaging process functional MRI during finger movements].
OBJECTIVE
To explore the techniques of RTIP-fMRI scanning and the correspondence between structure and functional changes of motor cortex during self-paced finger movements by RTIP-fMRI in normal volunteers.


METHODS
The 15 healthy volunteers were studied by RTIP-fMRI, and the activation tasks consisted of self-paced finger movements performed with the right and the left hands. Image postprocessing was done on the workstation by "correlation coefficient" algorithm analysis method, IAC and SPM software.


RESULTS
There was a good correspondence between the anatomical landmarks of the somatotopical organization of primary motor areas in the 15 volunteers; during the finger tasks, the functional changes occurred in the contralateral primary motor-somatosensory cortex (M1/S1), the supplementary motor area (SMA), and the ipsilateral primary motor cortex.


CONCLUSIONS
RTIP, a promising new technique, can localize the motor cortex accurately. It is superior to any other fMRI techniques, and may be used widely in the function research of the brain.
Tan
Chang-Lian
CL
Department of Radiology, Second Xiangya Hospital, Central South University, Changsha 410011, China. tan-changlianxy@yahoo.com.cn
Wu
Da-Xing
DX
Liu
Ya-Dong
YD
Yan
Li-Rong
LR
Yuan
Shu-Wen
SW
Zuo
Shang-Pi
SP
He
Zhong
Z
Du
Wan-Ping
WP
Situ
Wei-Jun
WJ
D000328:Adult; D001931:Brain Mapping; D003199:Computer Systems; D005260:Female; D005385:Fingers / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology; D013003:Somatosensory Cortex / Q000502:physiology*