title: Synthesis and antiproliferative activity of 2,6-dibenzylamino-3,5-dicyanopyridines on human cancer cell lines.
abstract: A new series of 2,6-dibenzylamino-3,5-dicyanopyridines were synthesized and evaluated for their in vitro anticancer activity toward cell lines of nine different types of human cancer. Some of newly prepared compounds demonstrated remarkable anticancer activity against most of the tested subpanel tumor cell lines.
authors.affiliation: Dipartimento di Tossicologia, Università degli Studi di Cagliari, Via Ospedale 72-09124 Cagliari, Italy. tcocco@unica.it
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Cocco
authors.forename: Cenzo
authors.initials: C
authors.lastname: Congiu
authors.forename: Valentina
authors.initials: V
authors.lastname: Lilliu
authors.forename: Valentina
authors.initials: V
authors.lastname: Onnis
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D011725:Pyridines