title: 17-beta-estradiol eluting stent versus phosphorylcholine-coated stent for the treatment of native coronary artery disease.
abstract: In this study we randomly compared the estradiol eluting stent (17-beta-E) with phosphorylcholine (PC)-coated stents in native coronary arteries. The incidence of angiographic restenosis was 23% in the 17-beta-E group and 31% in the PC group (p = 0.34). The major adverse cardiovascular event rates were also similar in the 2 groups (17% in the 17-beta-E group vs 22% in the PC group, p = 0.47). The mid-term clinical and angiographic outcomes did not indicate superiority of the 17-beta-E eluting stent over the control PC stent.
authors.affiliation: Interventional Cardiology Unit, San Raffaele Hospital, Milan, Italy.
authors.forename: Flavio
authors.initials: F
authors.lastname: Airoldi
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Mario
authors.forename: Flavio
authors.initials: F
authors.lastname: Ribichini
authors.forename: Patrizia
authors.initials: P
authors.lastname: Presbitero
authors.forename: Paolo
authors.initials: P
authors.lastname: Sganzerla
authors.forename: Valeria
authors.initials: V
authors.lastname: Ferrero
authors.forename: Corrado
authors.initials: C
authors.lastname: Vassanelli
authors.forename: Carlo
authors.initials: C
authors.lastname: Briguori
authors.forename: Mauro
authors.initials: M
authors.lastname: Carlino
authors.forename: Matteo
authors.initials: M
authors.lastname: Montorfano
authors.forename: Giuseppe G L
authors.initials: GG
authors.lastname: Biondi-Zoccai
authors.forename: Alaide
authors.initials: A
authors.lastname: Chieffo
authors.forename: Angela
authors.initials: A
authors.lastname: Ferrari
authors.forename: Antonio
authors.initials: A
authors.lastname: Colombo
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control; D004958:Estradiol / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010767:Phosphorylcholine / Q000627:therapeutic use*; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible; D010767:Phosphorylcholine; D004958:Estradiol