title: Selective azetidine and tetrahydropyridine formation via Pd-catalyzed cyclizations of allene-substituted amines and amino acids.
abstract: [reaction: see text] By choosing the right substituents either highly functionalized unusual four-membered ring amino acids or the isomeric pipecolic acid derivatives are obtained in enantiomerically pure form. Starting material is a linear allene-containing amino acid that has been resolved via biocatalysis.
authors.affiliation: Institute of Molecular Chemistry, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands. florisr@org.chem.uva.nl
authors.forename: F P
authors.initials: FP
authors.lastname: Rutjes
authors.forename: K C
authors.initials: KC
authors.lastname: Tjen
authors.forename: L B
authors.initials: LB
authors.lastname: Wolf
authors.forename: W F
authors.initials: WF
authors.lastname: Karstens
authors.forename: H E
authors.initials: HE
authors.lastname: Schoemaker
authors.forename: H
authors.initials: H
authors.lastname: Hiemstra