Pulmonary involvement in systemic sclerosis due to therapy and as a complication.
Lung involvement frequently occurs in systemic sclerosis (SS), similar to other connective tissue diseases. Sometimes lung disease may be a side effect of antirheumathic drugs. We report a case of a patient affected by SS, with isolated pulmonary hypertension, who developed bronchiolitis secondary to penicillamine. The latter was treated by withdraw of the drug without increasing the steroids. After one month, the patient's clinical conditions appeared improved.
Chiappini
F
F
Divisione di Pneumologia, Università Cattolica del Sacro Cuore, Roma, Italy. fabrizio.chiappini@fastwebnet.it
Zoli
A
A
Maugeri
L
L
D018501:Antirheumatic Agents / Q000009:adverse effects*; D001987:Bronchiectasis / Q000209:etiology; D001988:Bronchiolitis / Q000139:chemically induced*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D008875:Middle Aged; D010396:Penicillamine / Q000009:adverse effects*; D012595:Scleroderma, Systemic / Q000150:complications / Q000188:drug therapy*
D018501:Antirheumatic Agents; D010396:Penicillamine