title: Granular cell tumor of the neurohypophysis: report of a case with unusual age presentation.
abstract: Granular cell tumor (GCT) usually occurs as a solitary, small, nodular tumor and rarely grows to a sufficient size to present symptoms. The tumor is more prevalent in female adults. The authors report a case of an 8-year-old boy with GCT of the neurohypophysis presenting with central precocious puberty. Few cases of symptomatic GCT have been reported in the literature, none of them in a patient in the first decade of life. Clinical picture, histopathological features, and histogenesis of GCT of neurohypophysis are discussed.
authors.affiliation: Department of Pathology, Hospital de Clinicas, Universidade Federal do Paraná (UFPR), 80060-900 Curitiba, Paraná, Brazil.
authors.forename: Paulo R
authors.initials: PR
authors.lastname: Benites Filho
authors.forename: Daniele
authors.initials: D
authors.lastname: Sakamoto
authors.forename: Tiago Noguchi
authors.initials: TN
authors.lastname: Machuca
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Serapião
authors.forename: Leo
authors.initials: L
authors.lastname: Ditzel
authors.forename: Luiz F
authors.initials: LF
authors.lastname: Bleggi Torres
mesh_terms: D002648:Child; D016586:Granular Cell Tumor / Q000150:complications / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D011629:Puberty, Precocious / Q000209:etiology; D014057:Tomography, X-Ray Computed