title: Adenosquamous carcinoma of the uterine cervix--adjuvant chemotherapeutic treatment with paclitaxel and carboplatin; a case report.
abstract: Adenosquamous carcinoma of the uterine cervix is a rare mixture of malignant glandular and squamous epithelial elements. We present a case of a 56-year-old woman with Stage IV cervical carcinoma treated with paclitaxel and carboplatin chemotherapy after cytoreductive surgery. Solitary liver metastases were treated by ultrasound guided percutaneous sclerotherapy with 95% ethanol. For ten months the patient showed an objective response to the treatment with a good quality of life during that time. A year after the first, the second cytoreductive operation was performed and chemotherapy (paclitaxel, carboplatin, and epirubicin) followed. The patient died 20 months after establishing the diagnosis. Paclitaxel in combination with carboplatin as adjuvant chemotherapeutic treatment could be another promising agent for patients with advanced metastatic cervical adenocarcinoma.
authors.affiliation: Merkur University Hospital, Zagreb, Croatia.
authors.forename: V
authors.initials: V
authors.lastname: Radić
authors.forename: V
authors.initials: V
authors.lastname: Kukura
authors.forename: S
authors.initials: S
authors.lastname: Ciglar
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D018196:Carcinoma, Adenosquamous / Q000556:secondary / Q000628:therapy*; D015251:Epirubicin / Q000008:administration & dosage; D000431:Ethanol / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D015552:Injections, Intralesional; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy*; D008875:Middle Aged; D009367:Neoplasm Staging; D017239:Paclitaxel / Q000008:administration & dosage; D012597:Sclerosing Solutions / Q000008:administration & dosage; D015911:Sclerotherapy / Q000379:methods; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000628:therapy*
chemical_list: D012597:Sclerosing Solutions; D000431:Ethanol; D015251:Epirubicin; D016190:Carboplatin; D017239:Paclitaxel