title: Semaphorin5A expression in the developing chick telencephalon.
abstract: In the present study, we analyzed the expression of Semaphorin5A (Sema5A), a gene implicated in axon guidance and many other processes of neuronal development, in the developing chick telencephalon. By using a heterologous mouse probe and in situ hybridization techniques, we showed distinct patterns of Sema5A expression within the chick telencephalon. In early development, Sema5A was present in pallial regions, mainly in the neuroepithelium and in the deep mantle of ventral and lateral pallia, and in the subpallium. As development proceeds, some ventral pallial derivatives maintained a moderate to strong Sema5A expression, whereas other lateral or dorsal pallial derivatives showed low to moderate expression of Sema5A. The overall expression of Sema5A during development in the chick telencephalon was similar to that reported in mouse. Moreover, the expression of Sema5A in mesencephalic, diencephalic, and telencephalic centers related to the tectofugal system suggests an important role of this gene in the development.
authors.affiliation: Department of Cell Biology, Genetics and Physiology, Faculty of Biology, University of Málaga, Campus de Teatinos, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Pineda
authors.forename: Beatriz
authors.initials: B
authors.lastname: García
authors.forename: José Luis
authors.initials: JL
authors.lastname: Olmos
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Dávila
authors.forename: María Angeles
authors.initials: MA
authors.lastname: Real
authors.forename: Salvador
authors.initials: S
authors.lastname: Guirado
mesh_terms: D000367:Age Factors; D000818:Animals; D002642:Chick Embryo; D047108:Embryonic Development; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D017403:In Situ Hybridization / Q000379:methods; D008562:Membrane Glycoproteins / Q000378:metabolism*; D039961:Semaphorins / Q000378:metabolism*; D013687:Telencephalon / Q000196:embryology / Q000378:metabolism*
chemical_list: D008562:Membrane Glycoproteins; D039961:Semaphorins