An alternative agglutination assay to measure antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes.
Agglutination assays detect antibodies to variant parasite antigens expressed on the surface of Plasmodium falciparum-infected erythrocytes. Standard techniques require immediate analysis limiting the number of samples that can be processed simultaneously and preclude re-examination of slides. Fixed Giemsa-stained smears allow long-term storage and re-examination, without fluorescence microscopy.
Mann
E J
EJ
Department of Medicine, University of Melbourne, 4th Floor Clinical Sciences Building, Parkville, Victoria 3050, Australia. e.mann@pgrad.unimelb.edu.au
Rogerson
S J
SJ
Beeson
J G
JG
D000372:Agglutination Tests / Q000379:methods*; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000954:Antigens, Surface / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology* / Q000469:parasitology; D005260:Female; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis*; D008297:Male; D010963:Plasmodium falciparum / Q000276:immunology*; D011247:Pregnancy / Q000276:immunology
D000913:Antibodies, Protozoan; D000954:Antigens, Surface