Reversal of laser in situ keratomileusis-induced ectasia with intraocular pressure reduction.
A 40 year-old woman had laser in situ keratomileusis for --7.75 --0.75 x 20 in the right eye. Preoperative examinations, including topography, pachymetry, and intraocular pressures (IOPs), were normal, and best spectacle-corrected visual acuity (BSCVA) was 20/20 in each eye. By 4 months postoperatively, the uncorrected visual acuity and BSCVA in the right eye had decreased to 20/40. Corneal topography of that eye was consistent with ectasia. One drop per day of timolol 0.5% (Timoptic XE) was prescribed. Five months postoperatively, the IOP had decreased and BSCVA and topography had improved. At 11 months, BSCVA returned to 20/20 and corneal topography normalized. Topographic difference maps were used to monitor corneal shape changes. In this case, early reduction in IOP completely reversed the ectasia.
Hiatt
James Andrew
JA
Boxer Wachler Vision Institute, Beverly Hills, California 90210, USA.
Wachler
Brian S Boxer
BS
Grant
Colin
C
D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D003316:Corneal Diseases / Q000209:etiology / Q000503:physiopathology*; D019781:Corneal Topography; D004108:Dilatation, Pathologic / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D009216:Myopia / Q000601:surgery; D013999:Timolol / Q000008:administration & dosage*; D014792:Visual Acuity
D000959:Antihypertensive Agents; D013999:Timolol