Clinical observation on 96 cases of primary osteoporosis treated with kidney-tonifying and bone-strengthening mixture.
OBJECTIVE
To objectively evaluate the therapeutic effect and safety of Mixture for Nourishing Kidney and Strengthening Bone.


METHODS
Among 160 cases of osteoporosis under clinical observation, 96 patients in the treatment group were treated with Mixture for Nourishing Kidney and Strengthening Bone, 32 patients in the control group were given Shen Gu Capsule and 32 patients in the blank group were given no drug in half a year. Observation and determination were conducted on bone mineral density (BMD), clinical symptoms, bone gla protein (BGP), pyridinoline (PYD), estradiol (E2), testosterone (T), blood urea nitrogen (BUN), transaminase and routine test on blood and urine.


RESULTS
The comprehensive effect in the treatment group was remarkably superior to that in the control group.


CONCLUSIONS
The safe and reliable Chinese drug can enhance BMD, promote osteogenesis and inhibit bone absorption, hence treating osteoporosis with marked effect.
Mingyue
Wang
W
Xuanwu Hospital Affiliated to Capital Medical University, Beijing 100053, China.
Ling
Gong
G
Bei
Xia
X
Junqing
Cao
C
Peiqing
Zhou
Z
Jie
Hu
H
D000368:Aged; D000596:Amino Acids / Q000097:blood; D015519:Bone Density; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood; D010024:Osteoporosis / Q000188:drug therapy*; D008517:Phytotherapy
D000596:Amino Acids; D004365:Drugs, Chinese Herbal; D015675:Osteocalcin; C015484:pyridinoline