title: A new concept for esophageal resection--prevascularization: an experimental study.
abstract: We aim to elaborate upon a basically new animal model for esophageal resection. A total of 17 operations on 10 dogs were performed in order to develop a model in which resection of the cervical part of the esophagus involves two steps. The first step comprises omental flap transplantation from the abdomen to the cervical region by a microsurgical method, this omental flap improving the blood supply to the organ (prevascularization). The second step is segmental resection of the esophagus 14 days later. Of the five transplanted grafts, four still survived one week after the operation; for technical reasons, one flap had thrombotized. In the two long-term survival cases with esophageal resection after prevascularizastion, there were no major complications: the resections were successful, and the omental flap 'grew into' the tissue structure of the esophagus, assisting the healing of the anastomosis. Segmental resection of the cervical part of the esophagus was performed successfully via a new type of operation on dogs.
authors.affiliation: Bacs-Kiskun County Teaching Hospital Kecskemet, Department of Surgery, Kecskemet, Hungary. papszekeres@kmk.hu
authors.forename: J
authors.initials: J
authors.lastname: Pap-Szekeres
authors.forename: G
authors.initials: G
authors.lastname: Cserni
authors.forename: I
authors.initials: I
authors.lastname: Furka
authors.forename: M
authors.initials: M
authors.lastname: Svebis
authors.forename: T
authors.initials: T
authors.lastname: Cserni
authors.forename: E
authors.initials: E
authors.lastname: Brath
authors.forename: N
authors.initials: N
authors.lastname: Nemeth
authors.forename: I
authors.initials: I
authors.lastname: Miko
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D002196:Capillaries / Q000473:pathology; D004396:Coloring Agents; D004285:Dogs; D004730:Endothelium, Vascular / Q000473:pathology; D016629:Esophagectomy / Q000379:methods*; D004947:Esophagus / Q000098:blood supply*; D006085:Graft Survival / Q000502:physiology; D007150:Immunohistochemistry; D008866:Microsurgery; D023421:Models, Animal; D018919:Neovascularization, Physiologic / Q000502:physiology; D009852:Omentum / Q000098:blood supply / Q000637:transplantation*; D013524:Surgical Flaps; D013997:Time Factors; D014945:Wound Healing / Q000502:physiology
chemical_list: D004396:Coloring Agents