title: [Hepatitis A seroprevalence in HIV-infected patients].
abstract: OBJECTIVE
  The authors had for aim to prospectively study the hepatitis A seroprevalence of an HIV-infected population, followed-up in an outpatient clinic (CISIH Strasbourg).
  
  
  METHODS
  Blood tests were performed on all patients from September 2003 to March 2004 to screen for hepatitis A (total antibodies with Elisa).
  
  
  RESULTS
  The overall seroprevalence was 219/514 (56.6%), similar in male and female patients. It increased with age, especially in European patients (P = 0.003). The seroprevalence was lower in European subjects: 46.3% (while it reached 100% in sub-Saharan Africans), the prevalence was similar whatever the HIV risk group (46% in homosexual as well as in heterosexual patients, 44% in intravenous drug users). Hepatitis B or C co-infection did not increase the seroprevalence of hepatitis A. The hepatitis A seroprevalence was similar in various CD4 T cell count categories.
  
  
  CONCLUSIONS
  Our results stress the utility of hepatitis A serology in HIV-infected patients (more than 50% of European patients are non immune), and the importance of assessing hepatitis A vaccination.
authors.affiliation: Centre d'information et de soins de l'immunodéficience humaine, clinique médicale A, hôpitaux universitaires, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. david.rey@chru-strasbourg.fr
authors.forename: D
authors.initials: D
authors.lastname: Rey
authors.forename: E
authors.initials: E
authors.lastname: Frick-Michot
authors.forename: M
authors.initials: M
authors.lastname: Partisani
authors.forename: G
authors.initials: G
authors.lastname: Hess-Kempf
authors.forename: C
authors.initials: C
authors.lastname: Cheneau
authors.forename: M
authors.initials: M
authors.lastname: Priester
authors.forename: C
authors.initials: C
authors.lastname: Bernard-Henry
authors.forename: E
authors.initials: E
authors.lastname: de Mautort
authors.forename: M J
authors.initials: MJ
authors.lastname: Wendling
authors.forename: P
authors.initials: P
authors.lastname: Meyer
authors.forename: J M
authors.initials: JM
authors.lastname: Lang
mesh_terms: D000328:Adult; D017954:Africa South of the Sahara / Q000208:ethnology; D001208:Asia / Q000208:ethnology; D018791:CD4 Lymphocyte Count; D015897:Comorbidity; D005060:Europe / Q000208:ethnology; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006506:Hepatitis A / Q000453:epidemiology*; D035922:Hepatitis A Antibodies / Q000097:blood; D020010:Heterosexuality / Q000706:statistics & numerical data; D006716:Homosexuality / Q000706:statistics & numerical data; D006801:Humans; D016867:Immunocompromised Host; D007843:Latin America / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D065227:Transfusion Reaction
chemical_list: D035922:Hepatitis A Antibodies