title: Autoimmune chronic pancreatitis relapsing despite the maintenance dose of steroid.
abstract: Autoimmune chronic pancreatitis is a disease characterized by diffuse swelling of the pancreas, irregular narrowing of the main pancreatic duct and elevated levels of serum IgG, and lymphoplasmacytic infiltration is observed on histologic examination. Steroid therapy can dramatically reverse the clinical symptoms and the histologic and radiologic findings. It is known that recurrence is very rare after successful steroid treatment. Furthermore, there have not yet been any reports about a case that relapsed during maintenance therapy with low dose steroid. We experienced a rare case of autoimmune chronic pancreatitis that relapsed despite maintenance therapy with low-dose steroid, and the patient again responded to high-dose steroid.
authors.affiliation: Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Dae Keun
authors.initials: DK
authors.lastname: Pyun
authors.forename: Won Beom
authors.initials: WB
authors.lastname: Choi
authors.forename: Myung Hwan
authors.initials: MH
authors.lastname: Kim
authors.forename: Jae Pil
authors.initials: JP
authors.lastname: Yun
authors.forename: Sang Su
authors.initials: SS
authors.lastname: Lee
authors.forename: Dong Wan
authors.initials: DW
authors.lastname: Seo
authors.forename: Sung Koo
authors.initials: SK
authors.lastname: Lee
mesh_terms: D000284:Administration, Oral; D001327:Autoimmune Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone