[A case of high FDG-uptake into the myocardium after radiotherapy for esophageal cancer].
Radiation-induced cardiac disease has been observed in patients who have been irradiated to the mediastinum. A 68-year-old man who had been treated with chemoradiotherapy for esophageal cancer showed high FDG-uptake in his myocardium six months after the radiotherapy. The area of high FDG-uptake closely matched the irradiation field. This area also showed low 123I-BMIPP-uptake and delayed enhancement on Gd-MRI. These findings suggested the likelihood of radiation cardiomyopathy. There have been several studies on the detection of radiation cardiomyopathy by perfusion imaging, but few on detection by metabolic imaging or MRI. Early visualization and quantification of the degree of radiation cardiomyopathy might be possible by FDG-PET and 123I-BMIPP Gd-MRI.
Jingu
Keiichi
K
Department of Radiation Oncology, Tohoku University, Graduate School of Medicine.
Nemoto
Kenji
K
Kaneta
Tomohiro
T
Takai
Yoshihiro
Y
Ichinose
Azusa
A
Ogawa
Yoshihiro
Y
Yamada
Shogo
S
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D009202:Cardiomyopathies / Q000209:etiology; D004938:Esophageal Neoplasms / Q000532:radiotherapy*; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D049268:Positron-Emission Tomography; D011832:Radiation Injuries / Q000209:etiology
D019788:Fluorodeoxyglucose F18