Dendritic supramolecular assemblies for drug delivery.
Dendritic supramolecular assemblies were formed in water with Reichardt's dye or the anticancer drug 10-hydroxycamptothecin and the dendritic macromolecule, ([G4]-PGLSA-OH)2-PEG3400.
Morgan
Meredith T
MT
Duke University Medical Center, Durham, NC 27710, USA.
Carnahan
Michael A
MA
Finkelstein
Stella
S
Prata
Carla A H
CA
Degoricija
Lovorka
L
Lee
Stephen J
SJ
Grinstaff
Mark W
MW
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D050091:Dendrimers / Q000138:chemical synthesis*; D016503:Drug Delivery Systems; D005079:Excipients / Q000737:chemistry*; D019073:HT29 Cells; D006801:Humans; D000077146:Irinotecan; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011092:Polyethylene Glycols / Q000737:chemistry; D013386:Succinates / Q000737:chemistry
C518192:((G4)-PGLSA-OH)2-PEG3400 dendrimer; D000972:Antineoplastic Agents, Phytogenic; D050091:Dendrimers; D005079:Excipients; D013386:Succinates; D011092:Polyethylene Glycols; D000077146:Irinotecan; D002166:Camptothecin