[Research on hemostatic effect of total saponins of yinfenglun].
OBJECTIVE
To research the hemostatic effect of total saponins of Yinfenglun.


METHODS
Bleeding time and volume were deteminded in mice after tails being cut. Clotting times were researched on mice, rats and dogs. Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, PT, KPTT and ELT.


RESULTS
TSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system,and had no effect of antifibrinolysis.


CONCLUSIONS
There were obvious hemostatic effect of total saponins of Yinfenglun.
Peng
Dai-Yin
DY
Anhui College of Traditional Chinese Medicine, Hefei 230038, China.
Liu
Qing-Yun
QY
Dai
Min
M
Zi
Xiao-Mei
XM
Xu
Xian-Xiang
XX
D000818:Animals; D001760:Bleeding Time; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006490:Hemostatics / Q000494:pharmacology*; D019686:Lamiaceae / Q000737:chemistry; D008297:Male; D051379:Mice; D010314:Partial Thromboplastin Time; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011517:Prothrombin Time; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D014914:Whole Blood Coagulation Time
D004365:Drugs, Chinese Herbal; D006490:Hemostatics; D012503:Saponins