title: Occupational exposures and risk of adenocarcinoma of the lung in Uruguay.
abstract: OBJECTIVE
  To investigate occupational risks of lung adenocarcinoma in Uruguay and to confirm a previously reported increased risk among butchers.
  
  
  METHODS
  We conducted a case-control study among men in four major hospitals in Montevideo, based on interviews to 338 cases of lung adenocarcinoma and 1014 hospital-based controls. We calculated odds ratios (ORs) of lung adenocarcinoma for employment in 22 jobs, after adjustment for tobacco smoking and other potential confounders.
  
  
  RESULTS
  The OR was increased for employment as farmer, tractor driver, painter and medical worker, but no trend was suggested for duration of employment. Long-term employment as mason, glass worker or textile worker resulted in an increased OR. The OR for employment as butcher was 1.2 (95% confidence interval 0.7-2.1). The OR increased with increasing duration of self-reported exposure to formaldehyde.
  
  
  CONCLUSIONS
  Occupational exposures seem to play a limited role in causing lung adenocarcinoma among men in Uruguay. Employment as butcher was not confirmed as an important risk factor.
authors.affiliation: Departamento de Patología, Instituto Nacional de Oncología, Montevideo, Uruguay.
authors.forename: Eduardo
authors.initials: E
authors.lastname: De Stefani
authors.forename: Paolo
authors.initials: P
authors.lastname: Boffetta
authors.forename: Paul
authors.initials: P
authors.lastname: Brennan
authors.forename: Hugo
authors.initials: H
authors.lastname: Deneo-Pellegrini
authors.forename: Alvaro
authors.initials: A
authors.lastname: Ronco
authors.forename: Luis Piñeyro
authors.initials: LP
authors.lastname: Gutiérrez
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology* / Q000209:etiology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000009:adverse effects; D002273:Carcinogens; D016022:Case-Control Studies; D004391:Dust; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008460:Meat / Q000009:adverse effects; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000145:classification; D016017:Odds Ratio; D012307:Risk Factors; D012822:Silicon Dioxide / Q000009:adverse effects; D012907:Smoking / Q000009:adverse effects; D013784:Textiles / Q000009:adverse effects; D014583:Uruguay / Q000453:epidemiology
chemical_list: D002273:Carcinogens; D004391:Dust; D001194:Asbestos; D012822:Silicon Dioxide