Highly diastereoselective alkylation of aziridine-2-carboxylate esters: enantioselective synthesis of LFA-1 antagonist BIRT-377.
Patwardhan
Aniruddha P
AP
Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Pulgam
V Reddy
VR
Zhang
Yu
Y
Wulff
William D
WD
D000478:Alkylation; D001388:Aziridines / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D048289:Imidazolidines / Q000138:chemical synthesis* / Q000737:chemistry; D016169:Lymphocyte Function-Associated Antigen-1 / Q000737:chemistry*; D015394:Molecular Structure
D001388:Aziridines; C400461:BIRT 377; D004952:Esters; D048289:Imidazolidines; D016169:Lymphocyte Function-Associated Antigen-1; C073440:aziridine-2-carboxylic acid