title: Photoselective vaporization (PVP) versus transurethral resection of the prostate (TURP): a prospective bi-centre study of perioperative morbidity and early functional outcome.
abstract: OBJECTIVE
  To compare the early follow-up and perioperative morbidity of photoselective vaporization (PVP) and transurethral resection of the prostate (TURP) in patients (pts.) suffering from lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).
  
  
  METHODS
  101 pts. underwent PVP (n = 64) and TURP (n = 37) in a prospective, non-randomized bi-centre trial. Inclusion criteria were identical at both centres. Primary outcome parameters were maximum urinary flow rate (Q(max)), post-void residual volume (V(res)), International Prostate Symptom Score (IPSS). Secondary outcomes included intraoperative surgical parameters and perioperative and post-discharge morbidity.
  
  
  RESULTS
  Baseline characteristics of both groups were similar. Operating time was slightly shorter in the TURP group (p = 0.047). During TURP significant more irrigation solution was used (p < 0.001). Decrease of serum haemoglobin (p = 0.027) and serum sodium (p = 0.013) was larger after TURP. Catheter drainage was removed significant earlier after PVP than after TURP (p < 0.001). Outcome of Q(max), and IPSS were similar in both groups within 6 months. The sort of perioperative complications was different in both groups, however overall cumulative perioperative morbidity was comparable (PVP 39.1% versus TURP 43.2.1%; ns).
  
  
  CONCLUSIONS
  PVP provides excellent intraoperative safety, instant tissue removal, and immediate relief from obstructive voiding symptoms, similar to TURP. Early outcomes 6-months after PVP and TURP are comparable.
authors.affiliation: Department of Urology, University of Basel, Switzerland. bachmanna@uhbs.ch
authors.forename: Alexander
authors.initials: A
authors.lastname: Bachmann
authors.forename: Leander
authors.initials: L
authors.lastname: Schürch
authors.forename: Robin
authors.initials: R
authors.lastname: Ruszat
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Wyler
authors.forename: Hans-Helge
authors.initials: HH
authors.lastname: Seifert
authors.forename: Alexander
authors.initials: A
authors.lastname: Müller
authors.forename: Kurt
authors.initials: K
authors.lastname: Lehmann
authors.forename: Tullio
authors.initials: T
authors.lastname: Sulser
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003558:Cystoscopy / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D010149:Postoperative Pain / Q000175:diagnosis; D011300:Preoperative Care / Q000379:methods; D011336:Probability; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D018570:Risk Assessment; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D020728:Transurethral Resection of Prostate / Q000379:methods*; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology* / Q000601:surgery; D016055:Urinary Retention / Q000209:etiology / Q000503:physiopathology