title: [Ester derivatives of nucleoside inhibitors of reverse transcriptase: I. Molecular transport systems for 3'-azido-3'-deoxythymidine and 2',3'-didehydro-3'-deoxythymidine].
abstract: The methods of synthesis of the derivatives of nucleoside analogues esterified with various aliphatic, aromatic, and heteroaromatic acids and the construction from them of molecular transport systems that involve lipids, carbohydrates, peptides, and amino acids are discussed. The characteristics of the biological activity of a number of such systems are described.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Berezovskaia
authors.forename: M V
authors.initials: MV
authors.lastname: Chudinov
mesh_terms: D001692:Biological Transport; D004952:Esters; D006801:Humans; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D011355:Prodrugs / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D018119:Stavudine / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D015215:Zidovudine / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology
chemical_list: D004952:Esters; D009705:Nucleosides; D011355:Prodrugs; D018894:Reverse Transcriptase Inhibitors; D015215:Zidovudine; D018119:Stavudine