title: Reversible metastatic visceral calcification detected by 99mTc-methylene diphosphonate bone scanning in breast cancer.
abstract: Diffuse metastatic visceral calcification is rare in breast cancer. We report on a 57-year-old woman with breast cancer and hypercalcemia who had diffuse metastatic visceral calcifications on lungs, myocardium, stomach, and thyroid on a (99m)Tc-methylene diphosphonate bone scan. Visceral calcifications were completely resolved 6 months after successful anticancer and zoledronic acid treatments. Bone scanning offers a useful diagnostic tool for both identifying visceral calcification and assessing the response to therapy in chemosensitive malignities with hypercalcemia such as breast cancer.
authors.affiliation: Department of Nuclear Medicine, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Erdogan
authors.forename: Sabri
authors.initials: S
authors.lastname: Barutca
authors.forename: Yakup
authors.initials: Y
authors.lastname: Yurekli
authors.forename: Nezih
authors.initials: N
authors.lastname: Meydan
authors.forename: Kutsi
authors.initials: K
authors.lastname: Koseoglu
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001842:Bone and Bones / Q000378:metabolism*; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology*; D002113:Calcification, Physiologic; D002118:Calcium / Q000737:chemistry / Q000378:metabolism*; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D006338:Heart Neoplasms / Q000556:secondary; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000556:secondary; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000556:secondary; D013669:Technetium Tc 99m Medronate / Q000494:pharmacology*; D013964:Thyroid Neoplasms / Q000556:secondary; D013997:Time Factors; D000077211:Zoledronic Acid
chemical_list: D000970:Antineoplastic Agents; D004164:Diphosphonates; D007093:Imidazoles; D000077211:Zoledronic Acid; D002118:Calcium; D013669:Technetium Tc 99m Medronate