title: Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.
abstract: OBJECTIVE
  Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight.
  
  
  METHODS
  In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined.
  
  
  RESULTS
  As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly.
  
  
  CONCLUSIONS
  Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.
authors.affiliation: Department of Genetics, Institute of Biology, Swietokrzyska Academy, Kielce, Poland. b.witek@pu.kielce.pl
authors.forename: Bozena
authors.initials: B
authors.lastname: Witek
authors.forename: Ewa
authors.initials: E
authors.lastname: Ochwanowska
authors.forename: Jan
authors.initials: J
authors.lastname: Rafay
authors.forename: Adam
authors.initials: A
authors.lastname: Kolataj
authors.forename: Peter
authors.initials: P
authors.lastname: Chrenek
authors.forename: Karin
authors.initials: K
authors.lastname: Suvegova
authors.forename: Rastislav
authors.initials: R
authors.lastname: Jurcik
authors.forename: Alexander
authors.initials: A
authors.lastname: Sirotkin
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Darlak
mesh_terms: D000135:Acid Phosphatase / Q000097:blood; D000818:Animals; D018826:CD13 Antigens / Q000097:blood; D002402:Cathepsin D / Q000097:blood; D056668:Cathepsin L; D002403:Cathepsins / Q000097:blood; D003546:Cysteine Endopeptidases / Q000097:blood; D004950:Esterases / Q000097:blood; D005260:Female; D054439:Ghrelin; D006706:Homeostasis / Q000187:drug effects / Q000502:physiology; D006867:Hydrolases / Q000097:blood*; D008049:Lipase / Q000097:blood; D008247:Lysosomes / Q000201:enzymology*; D036361:Peptide Hormones / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D054439:Ghrelin; D036361:Peptide Hormones; D006867:Hydrolases; D004950:Esterases; D008049:Lipase; D000135:Acid Phosphatase; D002403:Cathepsins; D018826:CD13 Antigens; D003546:Cysteine Endopeptidases; D056668:Cathepsin L; D002402:Cathepsin D