Partial cloning and localisation of leptin and its receptor in the one-humped camel (Camelus dromedarius).
Based on the studies and results presented here, leptin and its receptor were expressed by adipose tissue, mammary alveolar epithelial cells, liver hepatocytes, and the lining epithelium of the bile duct of the one-humped camel (Camelus dromedarius). Our observations support the biological importance of leptin in the mammary gland as well as the likely local effect of leptin on the peripheral tissues. We suggest that there may be an association between hepatic leptin and the lipogenic activity of the liver in the dromedary camel.
Sayed-Ahmed
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A
Department of Physiology and Biochemistry, Faculty of Veterinary Science, Szent István University, P.O. Box 2, 1400 Budapest, Hungary.
Rudas
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P
Bartha
T
T
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001652:Bile Ducts / Q000166:cytology; D002162:Camelus; D003001:Cloning, Molecular; D004847:Epithelial Cells / Q000378:metabolism; D015870:Gene Expression; D022781:Hepatocytes / Q000378:metabolism; D020738:Leptin / Q000737:chemistry* / Q000378:metabolism; D008321:Mammary Glands, Animal / Q000166:cytology; D011956:Receptors, Cell Surface / Q000737:chemistry* / Q000378:metabolism; D054411:Receptors, Leptin; D014018:Tissue Distribution
D020738:Leptin; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin