No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females.
Monoamine oxidase A (MAO-A) is an enzyme involved in the metabolism of monoamine neurotransmitters such as dopamine, serotonin, and noradrenaline in the brain. Previous studies have demonstrated a significant association between MAO-A gene polymorphism and personality traits in males. The purpose of the present study was to examine this association in females. The subjects were 219 healthy Japanese females. We genotyped a variable number of tandem repeats located upstream of the MAO-A gene. Personality traits were assessed using the Temperament and Character Inventory (TCI). There was no association between any personality trait and MAO-A genotype. The present results do not support the hypothesis that MAO-A gene polymorphism is related to certain personality traits in females.
Hakamata
Yuko
Y
Department of Psychology and Human Developmental Sciences, Nagoya University, Graduate School of Education and Human Development, Japan.
Takahashi
Nagahide
N
Ishihara
Ryoko
R
Saito
Shinichi
S
Ozaki
Norio
N
Honjo
Shuji
S
Ono
Yutaka
Y
Inada
Toshiya
T
D000293:Adolescent; D000328:Adult; D004252:DNA Mutational Analysis / Q000379:methods; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008175:Lung Neoplasms / Q000201:enzymology* / Q000453:epidemiology* / Q000235:genetics; D008297:Male; D008995:Monoamine Oxidase / Q000235:genetics*; D010551:Personality / Q000235:genetics*; D010555:Personality Inventory; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics; D019655:Quantitative Trait, Heritable; D013223:Statistics as Topic
D008995:Monoamine Oxidase