Antibacterial 4-amino-N-(5-methylisoxazol-3-yl)-N-[(4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl]benzenesulfonamide.
In the molecule of the title compound, C26H21N3O5S, a new type of sulfonamide derivative with potential antibacterial activity, the flavone moiety is almost planar. The isoxazole and aminophenyl rings are also planar and make dihedral angles of 77.0 (2) and 81.4 (1) degrees , respectively, with the best plane of the flavone ring system. The crystal structure is stabilized by intra- and intermolecular hydrogen bonds.
Ozbey
Süheyla
S
Department of Engineering Physics, Faculty of Engineering, Hacettepe University, Beytepe 06800, Ankara, Turkey. sozbey@hacettepe.edu.tr
Akbaş
Arzu
A
Ayhan-Kilcigil
Gülgün
G
Ertan
Rahmiye
R
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001578:Benzopyrans / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D013449:Sulfonamides / Q000737:chemistry*; D000096926:Benzenesulfonamides
D000900:Anti-Bacterial Agents; D001578:Benzopyrans; D013449:Sulfonamides; C515418:4-amino-N-(5-methylisoxazol-3-yl)-N-((4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl)benzenesulfonamide; D000096926:Benzenesulfonamides