Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge.
The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.
Rodriguez
Marcela C
MC
Department of Chemical and Material Engineering, Biodesign Institute, Arizona State University, Tempe, AZ 85287-5801, USA.
Kawde
Abdel-Nasser
AN
Wang
Joseph
J
D015374:Biosensing Techniques; D001710:Biotin / Q000737:chemistry; D017097:Electric Impedance; D004563:Electrochemistry; D004566:Electrodes; D009113:Muramidase / Q000737:chemistry; D011506:Proteins / Q000737:chemistry*; D012996:Solutions; D013053:Spectrophotometry; D013499:Surface Properties
D011506:Proteins; D012996:Solutions; D001710:Biotin; D009113:Muramidase