The stages of type 1A diabetes.
We can now predict the development of type 1 diabetes in man because it is a chronic autoimmune disorder with defined stages of disease. We can also readily prevent the disorder in animal models. A major goal is safe prevention in man, and for this we will almost certainly need a better understanding of pathogenesis, coupled with rigorous clinical trials.
Babaya
Naru
N
Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, 12801 East 17th Avenue, Aurora, CO 80010-1763, USA.
Nakayama
Maki
M
Eisenbarth
George S
GS
D000818:Animals; D015551:Autoimmunity; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D004777:Environment; D020022:Genetic Predisposition to Disease; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D051379:Mice; D016688:Mice, Inbred NOD
D007328:Insulin