title: [Perinatological aspects of mutual relationships between asthma and pregnancy].
abstract: We have researched influence of asthma on pregnancy, fetus and delivery. We have verified asthmatic pregnant women on the basis of the relevant medical documentation (N=42). Control group is made of healthy pregnant women selected under the FIGO criteria (K=100). We followed up influence of asthma on pregnancy by evaluation of 6 variables which are determinants of pregnancy quality (spontanious abortion, missed abortion, hyperemesis gravidarum, EPH gestoses, prematurity and over-carried pregnancy. Authors didn't find any statistical significance in influence of asthma on pregnancy quality although the level of pathological situations in all researched variables was about 25% higher than in control group. In over-carried pregnancy variable statistically significant low level of cases was found in researched group. Influence of asthma on fetus was monitored with the methods of clinical measurements of fetuses biophysical profile, cardiotocographic index and amnioscopy. Significantly higher participation of pathological situations was found in all three monitored variables within researched group of pregnancies (p<0.01). We have monitored influence of asthma on delivery with the methods of clinical measurement ABS pregnant-asthmatic woman, ABS of the new-born baby, body mass of new-born baby and the kind of delivery. A statistically significant fall of pp O2 (p<0.01) was found as well as declination of actual pH of pregnant-asthmatic woman toward acidosis (p<0.01) during the second delivery stage. Kind of delivery is showing statistically high level of participation of surgical termination of delivery in researched group (SC and vacuum extraction)--(p<0.001).
authors.affiliation: Zavod za ginekologiju, perinatologiju i neplodnost Mehmedbasić.
authors.forename: Senad
authors.initials: S
authors.lastname: Mehmedbasić
authors.forename: Idriz
authors.initials: I
authors.lastname: Bukvić
mesh_terms: D000328:Adult; D001249:Asthma / Q000503:physiopathology; D036861:Delivery, Obstetric; D005260:Female; D047109:Fetal Development; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology; D011256:Pregnancy Outcome