Droplet fusion by alternating current (AC) field electrocoalescence in microchannels.
We present a system for the electrocoalescence of microfluidic droplets immersed in an immiscible solvent, where the undeformed droplet diameters are comparable to the channel diameter. The electrodes are not in direct contact with the carrier liquid or the droplets, thereby minimizing the risk of cross-contamination between different coalescence events. Results are presented for the coalescence of buffered aqueous droplets in both quiescent and flowing fluorocarbon streams, and on-flight coalescence is demonstrated. The capillary-based system presented here is readily amenable to further miniaturization to any lab-on-a-chip application where the conductivity of the droplets is much greater than the conductivity of the stream containing them, and should aid in the further application of droplet microreactors to biological analyses.
Chabert
Max
M
Laboratoire Physicochimie-Curie, CNRS/UMR 168, Institut Curie, Paris, France.
Dorfman
Kevin D
KD
Viovy
Jean-Louis
JL
D004560:Electricity; D004566:Electrodes; D046210:Microfluidic Analytical Techniques; D044085:Microfluidics / Q000379:methods*; D012997:Solvents / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D012997:Solvents; D014867:Water