title: Successful surgical correction of anal atresia in a transgenic cloned piglet.
abstract: Inbred strains of pig become indispensable for a wide range of biological studies. In biomedical science, it is generally accepted that somatic cell nuclear transfer (SCNT) technology with inbreed strain of pig is essential for xenotransplantation. In this study, we observed the anal atresia in a cloned pig which was derived from fetal fibroblast of inbreed miniature pig. A presumptive anal site of the cloned pig was excised and the rectum was sutured to apposed skin for treatment. This cloned piglet seemed to be normal with healthy status after surgery. This report can be useful for the treatment of anal atresia of cloned piglets.
authors.affiliation: Department of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Korea.
authors.forename: Gab Sang
authors.initials: GS
authors.lastname: Lee
authors.forename: Hye Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: So Hyun
authors.initials: SH
authors.lastname: Lee
authors.forename: Dae Yong
authors.initials: DY
authors.lastname: Kim
authors.forename: Kang Moon
authors.initials: KM
authors.lastname: Seo
authors.forename: Sang Hwan
authors.initials: SH
authors.lastname: Hyun
authors.forename: Sung Keun
authors.initials: SK
authors.lastname: Kang
authors.forename: Byeong Chun
authors.initials: BC
authors.lastname: Lee
authors.forename: Woo Suk
authors.initials: WS
authors.lastname: Hwang
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified / Q000601:surgery*; D001006:Anus, Imperforate / Q000235:genetics / Q000601:surgery / Q000662:veterinary*; D019976:Cloning, Organism; D005260:Female; D020022:Genetic Predisposition to Disease; D013552:Swine / Q000002:abnormalities* / Q000235:genetics / Q000601:surgery*