title: Pt-catalyzed pentannulations from in situ generated metallo-carbenoids utilizing propargylic esters.
abstract: A highly selective and efficient Pt-catalyzed pentannulation reaction beginning from propargylic esters is described. The key to this reaction is the use of a PtCl2(PPh3)2/PhIO catalyst combination that allows the in situ generation of Pt-carbenoid intermediates, which lead to good yields (61-84%) of the desired pentannulated compounds.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California 94720, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Bhanu Prasad
authors.forename: Francis K
authors.initials: FK
authors.lastname: Yoshimoto
authors.forename: Richmond
authors.initials: R
authors.lastname: Sarpong
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009944:Organoplatinum Compounds / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004952:Esters; D009944:Organoplatinum Compounds; D010984:Platinum