[Randomized controlled study of S (+) -ismer of ibuprofen supporsitory].
OBJECTIVE
To evaluate the efficacy and safety of S (+) - ismer of ibuprofen supporsitory.


METHODS
One hundred and three cases of postopterative pain and 60 cases of fever, altogether 163 patients were randomly divided into 2 groups: S (+) -ismer of ibuprofen supporsitory treatment group (one supporsitory per day for 3 days) and ibuprofen supporsitory treatment group (one supporsitory per day for 3 days). The therapeutic effect was assessed and the side-effects were observed between the 2 groups.


RESULTS
After being given medicine in the first 4 hours, pain intensity difference, pain remission degree and the dropped level of fever in S (+) -ismer of ibuprofen were all bigger than those of the ibuprofen supporsitory treatment group. There was no difference in side-effects between the 2 groups.


CONCLUSIONS
Therapeutic effect of S (+) -ismer of ibuprofen supporsitory is definite, whose action appears more quickly and stronger and it has fewer side-effects than those of ibuprofen supporsitory.
You
Yun-Hui
YH
Department of Rheumatology, Xiangya Hospital, Central South University Changsha, China.
Wu
Cai-Ling
CL
Gao
Jie-Sheng
JS
Huang
An-Lan
AL
Luo
Hui
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005334:Fever / Q000188:drug therapy*; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D013237:Stereoisomerism; D013488:Suppositories
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013488:Suppositories; D007052:Ibuprofen