title: Sealing of esophageal perforation or ruptures with expandable metallic stents: a prospective controlled study on treatment efficacy and limitations.
abstract: Esophageal perforations are surgical emergencies with high mortality rates. A variety of treatment strategies have been advocated. No single strategy has however, been fully applicable to deal with most situations. The aim of this study was to investigate if treatment with covered expandable metallic stents could offer a feasible option for the management of a leaking esophagus regardless of cause. Twenty-two consecutive patients with perforation or leakage from the intrathoracic esophagus were endoscopically treated with placement of a covered expandable metallic stent. Nine patients had esophageal cancer and 13 had benign underlying disease of whom two had a leakage from a surgical anastomosis. The leakage could be sealed in all but one patient. This patient died after an open esophageal diversion procedure. Twelve patients had an uneventful recovery, whereas three patients needed percutaneous drainage of abscesses and one drainage of the pleural cavity through a small thoracotomy. One patient required a conventional thoracotomy to drain the mediastinum. In total five (23%) patients died from the perforation within 30 days. Two of the deaths were unrelated and three (14%) related to the perforation. In patients with benign disease stents were removed or replaced after 3 weeks. In total 17 stents were successfully removed. Leakage from a damage esophagus can be effectively covered by expandable metallic stents seemingly regardless of the underlying cause and is likely to offer a good chance of survival even in severely ill patients.
authors.affiliation: Department of Surgery and Transplantation, Sahlgrenska University Hospital/Sahlgrenska, Göteborg, Sweden. erik.johnsson@vgregion.se
authors.forename: E
authors.initials: E
authors.lastname: Johnsson
authors.forename: L
authors.initials: L
authors.lastname: Lundell
authors.forename: B
authors.initials: B
authors.lastname: Liedman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D000714:Anastomosis, Surgical / Q000009:adverse effects; D002423:Cause of Death; D020878:Device Removal; D004322:Drainage; D004935:Esophageal Diseases / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000150:complications; D004939:Esophageal Perforation / Q000628:therapy*; D004945:Esophagoscopy; D004947:Esophagus / Q000601:surgery; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012422:Rupture, Spontaneous; D015607:Stents; D013908:Thoracotomy; D016896:Treatment Outcome
chemical_list: D000497:Alloys