Sturge-Weber syndrome: diffusion magnetic resonance imaging and proton magnetic resonance spectroscopy findings.
We report on the diffusion magnetic resonance imaging (MRI) and proton MR spectroscopy findings of a 26-year-old female patient with Sturge-Weber syndrome. Echo-planar trace diffusion MRI revealed mildly high signal intensity changes at parieto-occipital lobes on b = 1000 s/mm2 images, suggesting restricted diffusion. On corresponding apparent diffusion coefficient maps, those areas had moderately high signal intensity and high apparent diffusion coefficient values (around 0.9 x 10(-3) mm2/s) compared with the contralateral symmetrical normal side of the brain (0.776 x 10(-3) mm2/s). This finding was consistent with increased motion of water molecules (disintegration of the neural tissue) in these regions. Proton MR spectroscopy revealed decreased N-acetyl aspartate and increased choline peaks, indicating disintegration of neural tissue associated with neuronal loss as well.
Cakirer
S
S
Department of Radiology, Neuroradiology Section, Istanbul Sisli Etfal Hospital, Istanbul, Turkey. scakirer@yahoo.com
Yagmurlu
B
B
Savas
M R
MR
D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D002794:Choline / Q000378:metabolism; D003287:Contrast Media / Q000008:administration & dosage; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods; D005260:Female; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013341:Sturge-Weber Syndrome / Q000175:diagnosis* / Q000378:metabolism; D014057:Tomography, X-Ray Computed / Q000379:methods
D003287:Contrast Media; D001224:Aspartic Acid; C000179:N-acetylaspartate; D005682:Gadolinium; D002794:Choline