title: [Simultaneous determination of cimaterol, clenbuterol and salbutamol in feeds by capillary zone electrophoresis].
abstract: A method for simultaneous determination of cimaterol, clenbuterol and salbutamol in feeds was developed by capillary zone electrophoresis. The effects of the experimental conditions on the separation and determination of cimaterol, clenbuterol and salbutamol have been examined. Under the optimum conditions, all three compounds were completely separated in 8 min. The linear range of cimaterol, clenbuterol and salbutamol was 0.1-1.0 mg/L, and the detection limits (S/N = 3) were 0.02, 0.03 and 0.02 mg/L, respectively. The developed method has been used for the determination of spiked feed samples. The recoveries of cimaterol, clenbuterol and salbutamol were 89%-103%, 86%-91% and 83%-87%, respectively. The relative standard deviations for cimaterol, clenbuterol and salbutamol were 3.8%-4.3%, 3.6%-5.0% and 4.0%-5.6%, respectively. The proposed method is a sensitive, fast and simple method for the determination of cimaterol, clenbuterol and salbutamol in feeds.
authors.affiliation: Center Laboratory of Fuzhou University, Fuzhou 350002, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Duan
authors.forename: Hongqing
authors.initials: H
authors.lastname: Chen
authors.forename: Ying
authors.initials: Y
authors.lastname: Chen
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D000420:Albuterol / Q000032:analysis* / Q000302:isolation & purification; D000821:Animal Feed / Q000032:analysis*; D002976:Clenbuterol / Q000032:analysis* / Q000302:isolation & purification; D019075:Electrophoresis, Capillary; D004983:Ethanolamines / Q000032:analysis* / Q000302:isolation & purification; D012680:Sensitivity and Specificity
chemical_list: D004983:Ethanolamines; D000420:Albuterol; D002976:Clenbuterol; C047411:cimaterol