title: [Transmission of Haemophilus influenzae type b strains among children attending day-care centers and orphanages].
abstract: Goal of the work was to evaluate the differences level among H. influenzae strains of b serotype isolated from children attending day-care centres and orphanages and among strains isolated from invasive infections. In the work PFGE in Hib strains transmission examination and for epidemiological studies among three sources of invasive infection was applied. Among 35 Hib strains tested and control strain 8 different pulsotyped were found. Among 21 strains colonising the nasopharynx of healthy children, and among 13 Hib strains isolated from cerebrospinal fluid, 6 and 1 pulsotypes were found, respectively. Results obtained show that healthy children might be colonizing with genotypes characteristic for Hib strains isolated from invasive infections. In this view wider Hib vaccination seems be expected, as Hib circulation is common.
authors.affiliation: Zakład Badania Surowic i Szczepionek PZH w Warszawie.
authors.forename: Ewa
authors.initials: E
authors.lastname: Augustynowicz
authors.forename: Aneta
authors.initials: A
authors.lastname: Nowaczek
authors.forename: Leszek
authors.initials: L
authors.lastname: Szenborn
authors.forename: Dorota
authors.initials: D
authors.lastname: Banyś
authors.forename: Anna
authors.initials: A
authors.lastname: Gzyl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Dabrowski
authors.forename: Alfred
authors.initials: A
authors.lastname: Samet
authors.forename: Janusz
authors.initials: J
authors.lastname: Slusarczyk
mesh_terms: D002353:Carrier State; D003631:Day Care, Medical; D018562:Disease Transmission, Infectious; D006192:Haemophilus Infections / Q000517:prevention & control / Q000635:transmission*; D018073:Haemophilus Vaccines / Q000008:administration & dosage; D019741:Haemophilus influenzae type b / Q000145:classification* / Q000302:isolation & purification*; D006801:Humans; D019372:Orphanages; D011044:Poland
chemical_list: D018073:Haemophilus Vaccines