title: Preterm premature rupture of the membranes: current approaches to evaluation and management.
abstract: Preterm premature rupture of the membranes (PROM) complicates 3% of pregnancies and is responsible for approximately one third of all preterm births. Because preterm PROM presents a clinical situation where early delivery is to be anticipated and prenatal and neonatal complications are common, the physician caring for women with this common obstetric complication has an opportunity to intervene in a manner that can improve perinatal outcome. This article addresses clinically relevant questions regarding the evaluation and management of preterm PROM.
authors.affiliation: Department of Reproductive Biology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH 44109, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Mercer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001510:Bed Rest; D005260:Female; D005315:Fetal Diseases / Q000517:prevention & control; D005322:Premature Rupture of Fetal Membranes / Q000175:diagnosis* / Q000628:therapy*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control; D047928:Premature Birth / Q000517:prevention & control*; D018570:Risk Assessment
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents