Antibacterial agents: patent highlights January 2005 to June 2005.
This review summarizes patents claiming novel antibacterial agents published between January and June 2005. A total of 50 patents covering beta-lactam antibiotics, beta-lactamase inhibitors, macrolide, oxazolidinone, quinolone and quinoline derivatives, and miscellaneous agents such as peptide deformylase inhibitors are selected for review. The majority of the patents disclosed the syntheses and biological activities of novel agents, and novel uses, improved chemical processes and formulations of known antibiotics. Details of a novel 2,3-dihydro-6-nitro-imidazo[2,1-b]oxazole derivative with excellent activity against Mycobacterium tuberculosis, among others, are also presented.
Phillips
Oludotun A
OA
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, Safat, Kuwait. dphillips@hsc.edu.kw
D000818:Animals; D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D007769:Lactams / Q000494:pharmacology; D018942:Macrolides / Q000494:pharmacology; D010080:Oxazoles / Q000494:pharmacology; D015363:Quinolones / Q000494:pharmacology; D065093:beta-Lactamase Inhibitors
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D007769:Lactams; D018942:Macrolides; D010080:Oxazoles; D015363:Quinolones; D065093:beta-Lactamase Inhibitors