Pregnancy outcome after exposure to injectable ribavirin during embryogenesis.
We describe normal pregnancy outcome in a case of first trimester exposure to injectable ribavirin in a 36-year-old pregnant woman who received three intramuscular injections of ribavirin for suspected SARS. She delivered at 40 weeks of gestation a healthy baby girl. In pediatric follow up at 8 month of age, physical examination and neurodevelopmental milestones were normal.
Rezvani
Massoud
M
The Hospital for Sick Children, Division of Clinical Pharmacology, The Motherisk Program, 555 University Avenue, Toronto, Ont., Canada M5G 1X8.
Koren
Gideon
G
D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D047108:Embryonic Development / Q000187:drug effects*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D011247:Pregnancy; D011256:Pregnancy Outcome; D012254:Ribavirin / Q000008:administration & dosage / Q000627:therapeutic use*; D045169:Severe Acute Respiratory Syndrome / Q000188:drug therapy*
D000998:Antiviral Agents; D012254:Ribavirin