Constituents of leaves of Phellodendron japonicum MAXIM. and their antioxidant activity.
Three new flavonoid derivatives, 6'''-O-acetyl amurensin (1), 6'''-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.
Chiu
Chih-Yang
CY
Department of Chemistry, National Cheng Kung University, Tainan 701,Taiwan, R.O.C.
Li
Chia-Ying
CY
Chiu
Chao-Chen
CC
Niwa
Masatake
M
Kitanaka
Susumu
S
Damu
Amooru Gangaiah
AG
Lee
E-Jian
EJ
Wu
Tian-Shung
TS
D000975:Antioxidants / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry; D002855:Chromatography, Thin Layer; D006834:Hydrazines / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D032102:Phellodendron / Q000737:chemistry*; D010851:Picrates; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
D000975:Antioxidants; D001713:Biphenyl Compounds; D006834:Hydrazines; D007202:Indicators and Reagents; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl