Cytokine profile and immune status of patients with chronic glomerulonephritis concomitant with chronic opisthorchiasis.
Decrease in the absolute count of T lymphocytes in the peripheral blood (mainly CD4+ cells), activation of humoral immunity with accumulation of immune complexes, and suppression of the neutrophil metabolic activity were detected in patients with chronic glomerulonephritis in the presence of opisthorchis invasion. Imbalance in the serum concentrations of cytokines produced by T-helper subpopulations (predominance of Th products) was detected.
Kalyuzhina
E V
EV
Siberian State Medical University, Tomsk.
Kalyuzhin
O V
OV
D000293:Adolescent; D000328:Adult; D015703:Antigens, CD / Q000097:blood; D016022:Case-Control Studies; D002908:Chronic Disease; D016207:Cytokines / Q000097:blood*; D005921:Glomerulonephritis / Q000097:blood / Q000150:complications / Q000276:immunology*; D006801:Humans; D009889:Opisthorchiasis / Q000097:blood / Q000150:complications / Q000276:immunology*
D015703:Antigens, CD; D016207:Cytokines