[Imaging of CNS manifestations of tuberous sclerosis in children].
Tuberous sclerosis (TS) is a frequent phakomatosis, with autosomal dominant transmission. The diagnosis relies on a list of criteria (2 major criteria or 1 major criterion and 2 minor criteria). Brain MRI is very important for diagnosis, already showing the major signs during fetal life: subependymal nodules, tubers and giant cell astrocytomas. In childhood, FLAIR sequences are the more interesting while in fetuses, neonates and infants T1 sequences are required because of the myelination process.
Adamsbaum
C
C
Service de Radiopédiatrie, Hôpital St Vincent de Paul, 82 avenue Denfert Rochereau, 75674 Paris 14.
Merzoug
V
V
Kalifa
G
G
D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000175:diagnosis* / Q000209:etiology; D005315:Fetal Diseases / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007223:Infant; D011296:Prenatal Diagnosis; D011859:Radiography; D014402:Tuberous Sclerosis / Q000150:complications / Q000175:diagnosis* / Q000523:psychology