Prolonged QT interval in an infant of a fluoxetine treated mother.
Fluoxetine is an antidepressant drug, only recently discovered to be a QT interval prolonging agent. The first case is presented of an infant of a mother treated with fluoxetine during pregnancy who had a transiently prolonged QTc interval, concluded to be drug induced. Clinical and electrocardiographic monitoring of newborns of antidepressant treated mothers is needed.
Dubnov
G
G
Department of Neonatology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel. gald@clalit.org.il
Fogelman
R
R
Merlob
P
P
D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D003866:Depressive Disorder / Q000188:drug therapy; D004562:Electrocardiography; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D008133:Long QT Syndrome / Q000139:chemically induced*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011297:Prenatal Exposure Delayed Effects
D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine