Controlled spacing of cationic gold nanoparticles by nanocrown RNA.
Using atomic force microscopy, we describe the linear arrangement of cationic gold nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the regular spacing of nanoparticles is controlled by the RNA architecture acting as nanocrown scaffoldings. Thus, precise positioning of molecular components can be accomplished with RNA not only through electrostatic but also via size and shape recognitions.
Koyfman
Alexey Y
AY
Department of Chemistry and Biochemistry, University of California - Santa Barbara, 93106-9510, USA.
Braun
Gary
G
Magonov
Sergei
S
Chworos
Arkadiusz
A
Reich
Norbert O
NO
Jaeger
Luc
L
D002412:Cations; D047248:Crown Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D008956:Models, Chemical; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size; D011506:Proteins / Q000737:chemistry; D012313:RNA / Q000737:chemistry*; D013860:Thiocholine / Q000737:chemistry
D002412:Cations; D047248:Crown Compounds; D011506:Proteins; D013860:Thiocholine; D012313:RNA; D006046:Gold