title: An integrated database of the ascidian, Ciona intestinalis: towards functional genomics.
abstract: An integrated genome database is essential for future studies of functional genomics. In this study, we update cDNA and genomic resources of the ascidian, Ciona intestinalis, and provide an integrated database of the genomic and cDNA data by extending a database published previously. The updated resources include over 190,000 ESTs (672,396 in total together with the previous ESTs) and over 1,000 full-insert sequences (6,773 in total). In addition, results of mapping information of the determined scaffolds onto chromosomes, ESTs from a full-length enriched cDNA library for indication of precise 5'-ends of genes, and comparisons of SNPs and indels among different individuals are integrated into this database, all of these results being reported recently. These advances continue to increase the utility of Ciona intestinalis as a model organism whilst the integrated database will be useful for researchers in comparative and evolutionary genomics.
authors.affiliation: Department of Zoology, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan. yutaka@ascidian.zool.kyoto-u.ac.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Satou
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawashima
authors.forename: Eiichi
authors.initials: E
authors.lastname: Shoguchi
authors.forename: Akie
authors.initials: A
authors.lastname: Nakayama
authors.forename: Nori
authors.initials: N
authors.lastname: Satoh
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002938:Ciona intestinalis / Q000235:genetics*; D018076:DNA, Complementary / Q000235:genetics; D030541:Databases, Genetic; D020224:Expressed Sequence Tags; D016678:Genome; D023281:Genomics / Q000379:methods*; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
chemical_list: D018076:DNA, Complementary