title: Antibody-based approaches to diagnosis and characterization of oxidative phosphorylation diseases.
abstract: Mitochondrial disorders caused by defects in oxidative phosphorylation function are difficult to diagnose. Here we review the emerging use of antibody-based approaches for this diagnosis. Novel methods involving immunohistochemistry and immunocapture of defective enzymes for characterization are described that add to the arsenal of approaches available.
authors.affiliation: Institute of Molecular Biology, University of Oregon, Eugene, OR 97403 1229, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Hanson
authors.forename: M F
authors.initials: MF
authors.lastname: Marusich
authors.forename: R A
authors.initials: RA
authors.lastname: Capaldi