Fatigue at long-term follow-up in young adults with cerebral infarction.
BACKGROUND
To study the impact of fatigue in young ischaemic stroke patients.


METHODS
The Fatigue Severity Scale score was obtained in 192 patients (mean time 6.0 years after the stroke) and 212 controls.


RESULTS
Fatigue was associated with cerebral infarction in a multivariate analysis of patients and controls (p = 0.002). Fatigue was independently associated with unfavourable functional outcome (p = 0.001), depression (p < 0.001), and basilar artery infarction through interaction with the modified Rankin Scale score (p = 0.047) in patients.


CONCLUSIONS
Fatigue is frequent in young adults with cerebral infarction. Stroke-related factors independently associated with fatigue include functional outcome. Stroke location may influence fatigue.
Naess
Halvor
H
Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway. halvor.naess@haukeland.no
Nyland
Harald I
HI
Thomassen
Lars
L
Aarseth
Jan
J
Myhr
Kjell-Morten
KM
D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D002544:Cerebral Infarction / Q000150:complications* / Q000523:psychology; D003863:Depression / Q000209:etiology / Q000523:psychology; D004185:Disability Evaluation; D005221:Fatigue / Q000209:etiology* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011584:Psychology; D014715:Vertebrobasilar Insufficiency / Q000150:complications / Q000523:psychology