The genetics of shared autoimmunity.
Researchers have long suspected that genetic susceptibility is shared among autoimmune diseases. With the increased understanding of genetic risks and disease etiology, we are beginning to comprehend the nature of shared autoimmunity. This article briefly describes the most recent advances in the genetics of autoimmunity and the novel genes discovered.
Alarcón-Riquelme
Marta E
ME
Department of Medical Genetics, Uppsala University, Sweden. marta.alarcon@genpat.uu.se
D000818:Animals; D015703:Antigens, CD; D000954:Antigens, Surface / Q000235:genetics / Q000276:immunology; D051017:Apoptosis Regulatory Proteins; D015551:Autoimmunity / Q000235:genetics* / Q000276:immunology; D006801:Humans; D026901:Membrane Transport Proteins / Q000235:genetics / Q000276:immunology; D051379:Mice; D009154:Mutation / Q000276:immunology; D027701:Organic Cation Transport Proteins; D011110:Polymorphism, Genetic / Q000276:immunology; D061026:Programmed Cell Death 1 Receptor; D054596:Protein Tyrosine Phosphatase, Non-Receptor Type 22; D017027:Protein Tyrosine Phosphatases / Q000235:genetics / Q000276:immunology; D027981:Symporters
D015703:Antigens, CD; D000954:Antigens, Surface; D051017:Apoptosis Regulatory Proteins; D026901:Membrane Transport Proteins; D027701:Organic Cation Transport Proteins; C105992:PDCD1 protein, human; C491383:Pdcd1 protein, mouse; D061026:Programmed Cell Death 1 Receptor; C109807:SLC22A4 protein, human; D027981:Symporters; C516765:PTPN22 protein, human; D054596:Protein Tyrosine Phosphatase, Non-Receptor Type 22; D017027:Protein Tyrosine Phosphatases; C516766:Ptpn22 protein, mouse