Autoimmune chronic pancreatitis relapsing despite the maintenance dose of steroid.
Autoimmune chronic pancreatitis is a disease characterized by diffuse swelling of the pancreas, irregular narrowing of the main pancreatic duct and elevated levels of serum IgG, and lymphoplasmacytic infiltration is observed on histologic examination. Steroid therapy can dramatically reverse the clinical symptoms and the histologic and radiologic findings. It is known that recurrence is very rare after successful steroid treatment. Furthermore, there have not yet been any reports about a case that relapsed during maintenance therapy with low dose steroid. We experienced a rare case of autoimmune chronic pancreatitis that relapsed despite maintenance therapy with low-dose steroid, and the patient again responded to high-dose steroid.
Pyun
Dae Keun
DK
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Choi
Won Beom
WB
Kim
Myung Hwan
MH
Yun
Jae Pil
JP
Lee
Sang Su
SS
Seo
Dong Wan
DW
Lee
Sung Koo
SK
D000284:Administration, Oral; D001327:Autoimmune Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D011239:Prednisolone