Epidemiology, risk factors, and genetics of high-altitude-related pulmonary disease.
High-altitude-related pulmonary disease is a spectrum of acute and chronic illnesses with a well-described epidemiology. The risk for these illnesses is related to well-known environmental risk factors and lesser-known but important genetic factors. Prevention of acute high-altitude illness is possible in most visitors from lower elevations. Chronic high-altitude illnesses have an important worldwide impact.
Maloney
James P
JP
Division of Pulmonary and Critical Medicine, University of Colorado Health Sciences Center, 4220 East 9th Avenue, C-272, Denver, CO 80262, USA. james.maloney@uchsc.edu
Broeckel
Ulrich
U
D000222:Adaptation, Physiological / Q000502:physiology; D000532:Altitude Sickness / Q000150:complications*; D001274:Atmospheric Pressure; D006801:Humans; D000860:Hypoxia / Q000150:complications; D008171:Lung Diseases / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics*; D012307:Risk Factors