title: Renal dysfunction after oral acyclovir treatment in a geriatric woman: a case report.
abstract: Oral acylovir treatment rarely results in renal dysfunction. In reported cases concerning renal failure due to oral acyclovir, baseline creatinine levels were unknown or impaired or a predisposing factor for nephrotoxicity was present. We report a 78-y-old female with documented normal baseline renal function and no contributing possible nephrotoxic factor, who developed irreversible renal dysfunction after oral acyclovir treatment. We suggest that in geriatric age groups chronic renal insufficiency should be taken into consideration during oral acyclovir therapy.
authors.affiliation: Department of Internal Medicine, Division of Geriatric Medicine, Hacettepe University, Ankara, Turkey. bbdogu@yahoo.com
authors.forename: Burcu Balam
authors.initials: BB
authors.lastname: Yavuz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cankurtaran
authors.forename: Meltem
authors.initials: M
authors.lastname: Halil
authors.forename: Neslihan
authors.initials: N
authors.lastname: Dagli
authors.forename: Alper
authors.initials: A
authors.lastname: Kirkpantur
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000009:adverse effects*; D000284:Administration, Oral; D000368:Aged; D005260:Female; D005853:Geriatrics; D006801:Humans; D051437:Renal Insufficiency / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D000212:Acyclovir