title: HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication.
abstract: We identified a total 15 patients who have maintained undetectable plasma HIV RNA loads without antiretroviral treatment for >10 years from cohorts of 1300 and 1551 patients infected with human immunodeficiency virus (HIV). These 15 patients, whom we have referred to as "HIV controllers," are characterized by a low HIV DNA load in peripheral blood mononuclear cells and by a strong HIV-specific immune response.
authors.affiliation: INSERM E-0109, Faculté de Médecine Paris-Sud, Université Paris XI, Service de Santé Publique, Bicêtre, France. olivier.lambotte@bct.ap-hop-paris.fr
authors.forename: Olivier
authors.initials: O
authors.lastname: Lambotte
authors.forename: Faroudy
authors.initials: F
authors.lastname: Boufassa
authors.forename: Yoann
authors.initials: Y
authors.lastname: Madec
authors.forename: Ahn
authors.initials: A
authors.lastname: Nguyen
authors.forename: Cécile
authors.initials: C
authors.lastname: Goujard
authors.forename: Laurence
authors.initials: L
authors.lastname: Meyer
authors.forename: Christine
authors.initials: C
authors.lastname: Rouzioux
authors.forename: Alain
authors.initials: A
authors.lastname: Venet
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Delfraissy
mesh_terms: D000328:Adult; D000368:Aged; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000276:immunology / Q000821:virology*; D015497:HIV-1 / Q000276:immunology / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood; D013997:Time Factors; D019562:Viral Load; D014779:Virus Replication / Q000502:physiology*
chemical_list: D012367:RNA, Viral