title: [Abnormal metabolism of triglycerides fractions in chronic pancreatitis and results after the operation treatment].
abstract: This study was undertaken to determine how fats digestion processes were damaged due to chronic pancreatitis, and identify, whether lipid metabolism improved after surgical treatment the patients with chronic pancreatitis. Total lipids, triglycerides, diglycerides and free fatty acids levels in serum and stool were analysed, using chemical tests, thin-layer chromatography and electrophoresis of serum lipoproteins. The patients before the operations showed higher total lipids and triglycerides concentrations, and lower concentrations of diglycerides and free fatty acids in stool. These patients had high triglycerides, chylomicrons, VLDL, LDL-CH concentrations, and low-diglycerides, free fatty acids, HDL-CH concentrations in serum. These data were statistically significant. After the operations and substitution therapy it was observed normalization of the total lipids and lipids fractions levels in stool and in serum. Concentrations of LDL-CH and HDL-CH fractions were irregular. We conclude, that these lipids parameters could be used in diagnosing and monitoring the results of chronic pancreatitis surgical treatment.
authors.affiliation: Klinika Chirurgii Przewodu Pokarmowego i Chirurgii Ogólnej AM we Wrocławiu.
authors.forename: Dorota
authors.initials: D
authors.lastname: Diakowska
authors.forename: Witold
authors.initials: W
authors.lastname: Knast
authors.forename: Witold
authors.initials: W
authors.lastname: Diakowski
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Grabowski
authors.forename: Piotr
authors.initials: P
authors.lastname: Szelachowski
authors.forename: Piotr
authors.initials: P
authors.lastname: Pelczar
mesh_terms: D000328:Adult; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D002908:Chronic Disease; D002914:Chylomicrons / Q000097:blood; D004075:Diglycerides / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood / Q000378:metabolism* / Q000601:surgery*; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D002914:Chylomicrons; D004075:Diglycerides; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides