title: Constituents of leaves of Phellodendron japonicum MAXIM. and their antioxidant activity.
abstract: Three new flavonoid derivatives, 6'''-O-acetyl amurensin (1), 6'''-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.
authors.affiliation: Department of Chemistry, National Cheng Kung University, Tainan 701,Taiwan, R.O.C.
authors.forename: Chih-Yang
authors.initials: CY
authors.lastname: Chiu
authors.forename: Chia-Ying
authors.initials: CY
authors.lastname: Li
authors.forename: Chao-Chen
authors.initials: CC
authors.lastname: Chiu
authors.forename: Masatake
authors.initials: M
authors.lastname: Niwa
authors.forename: Susumu
authors.initials: S
authors.lastname: Kitanaka
authors.forename: Amooru Gangaiah
authors.initials: AG
authors.lastname: Damu
authors.forename: E-Jian
authors.initials: EJ
authors.lastname: Lee
authors.forename: Tian-Shung
authors.initials: TS
authors.lastname: Wu
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry; D002855:Chromatography, Thin Layer; D006834:Hydrazines / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D032102:Phellodendron / Q000737:chemistry*; D010851:Picrates; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D006834:Hydrazines; D007202:Indicators and Reagents; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl