Comb-shaped poly(ethylene glycol)-modified subtilisin Carlsberg is soluble and highly active in ionic liquids.
Subtilisin Carlsberg conjugated with comb-shaped poly(ethylene glycol) was solubilized in common ionic liquids without adding water, and exhibited higher transesterification activity in an ionic liquid, [Emim][Tf2N], than in organic solvents commonly used for enzymatic biotransformation.
Nakashima
Kazunori
K
Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka 812-8581, Japan.
Maruyama
Tatsuo
T
Kamiya
Noriho
N
Goto
Masahiro
M