title: Patent foramen ovale and left atrial appendage: new devices and methods for closure.
abstract: Transcatheter closure of atrial septal defects (ASDs) has become a routine procedure in many countries of the world. It spares many patients cardiac surgery and has proven efficacy in long-term studies. Device improvements have resulted in a continuous reduction of complications and of residual shunt frequency. ASD closure devices are also used for transcatheter closure of patent foramen ovale (PFO) for prevention of paradoxical embolism. In the past few years, there has been increasing interest in developing devices specifically designed for PFO closure. Although transcatheter closure of ASDs is well established, interventional closure of the left atrial appendage is in its development stage. Closure of the left atrial appendage is designed to reduce the risk of stroke in patients with atrial fibrillation in whom anticoagulation with Warfarin-type drugs is contraindicated. This article describes the latest developments in catheter closure of PFO and the left atrial appendage.
authors.affiliation: CardioVascular Center Frankfurt, Sankt Katharinen, Frankfurt, 60389, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Hein
authors.forename: Y
authors.initials: Y
authors.lastname: Bayard
authors.forename: M
authors.initials: M
authors.lastname: Taaffe
authors.forename: F
authors.initials: F
authors.lastname: Büscheck
authors.forename: S
authors.initials: S
authors.lastname: Ostermayer
authors.forename: K
authors.initials: K
authors.lastname: Billinger
authors.forename: M
authors.initials: M
authors.lastname: Reschke
authors.forename: T
authors.initials: T
authors.lastname: Trepels
authors.forename: H
authors.initials: H
authors.lastname: Lissmann-Jensen
authors.forename: K
authors.initials: K
authors.lastname: Lang
authors.forename: A
authors.initials: A
authors.lastname: Römer
authors.forename: N
authors.initials: N
authors.lastname: Wilson
authors.forename: H
authors.initials: H
authors.lastname: Sievert
mesh_terms: D020517:Atrial Appendage / Q000473:pathology; D021721:Balloon Occlusion / Q000295:instrumentation*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D006348:Cardiac Surgical Procedures / Q000295:instrumentation; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004867:Equipment Design / Q000295:instrumentation; D006344:Heart Septal Defects, Atrial / Q000628:therapy*; D006801:Humans