title: Ongoing queries: Interpretation of serology in asymptomatic or atypical chronic Q fever.
abstract: Chronic Q fever, predominantly associated with endocarditis, can develop insidiously. Although the diagnosis may be straightforward with a typical clinical presentation, incidental discovery of positive Coxiella burnetii serology poses a difficult clinical challenge. We describe the cases of two such patients and review the literature on the serological diagnosis of chronic Q fever.
authors.affiliation: Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Sheffield, UK. thushandesilva@hotmail.com
authors.forename: T
authors.initials: T
authors.lastname: de Silva
authors.forename: A
authors.initials: A
authors.lastname: Chapman
authors.forename: G
authors.initials: G
authors.lastname: Kudesia
authors.forename: M
authors.initials: M
authors.lastname: McKendrick
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood*; D013956:Antithyroid Agents / Q000627:therapeutic use; D002231:Carbimazole / Q000627:therapeutic use; D002908:Chronic Disease; D016997:Coxiella burnetii / Q000276:immunology* / Q000302:isolation & purification; D004318:Doxycycline / Q000627:therapeutic use; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D011778:Q Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D012008:Recurrence; D013971:Thyrotoxicosis / Q000150:complications / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D013956:Antithyroid Agents; D007074:Immunoglobulin G; D002231:Carbimazole; D004318:Doxycycline