title: False-positive fluorine-18 fluorodeoxy-D-glucose positron emission tomography imaging caused by retained gauze in a woman with recurrent ovarian cancer: a case report.
abstract: We report a case of a 47-year-old woman with a false-positive [18F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) result caused by retained gauze during resection of liver metastasis for a Stage IV ovarian cancer at primary cytoreductive surgery. She achieved complete remission and remained free of progression for seven years. Owing to elevation of CA-125, computed tomography and PET studies were performed, and both showed two potentially resectable lesions. One was located ventral to the diaphragmatic surface of the left hepatic lobe and the other was around the gauze at the right hepatorenal fossa. During surgical intervention, the left supraheptic tumor was excised and the gauze with surrounding granulation was removed. However, the former proved to be recurrent ovarian cancer with the latter proven false-positive. This case demonstrates that PET results should be interpreted with caution in differentiating a benign inflammatory process from malignant abnormalities, especially in regions with a high probability of granulomatous lesions.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
authors.forename: M Y
authors.initials: MY
authors.lastname: Chen
authors.forename: K K
authors.initials: KK
authors.lastname: Ng
authors.forename: S Y
authors.initials: SY
authors.lastname: Ma
authors.forename: T I
authors.initials: TI
authors.lastname: Wu
authors.forename: T C
authors.initials: TC
authors.lastname: Chang
authors.forename: C H
authors.initials: CH
authors.lastname: Lai
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000000981:diagnostic imaging* / Q000601:surgery / Q000628:therapy; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery / Q000628:therapy; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013514:Surgical Procedures, Operative; D015503:Surgical Sponges
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18