Changes in ultraweak photon emission and heart rate variability of epinephrine-injected rats.
Ultraweak photons which are spontaneously emitted from a living body may be applicable as a non-invasive tool to characterize the physiological state of the living body. We investigated changes in the intensity of ultraweak photon emission, body temperature and the cardiovascular autonomic activity induced by epinephrine injection to rats. A high dose of epinephrine can make changes to the cardiovascular autonomic activity or body temperature. Photon emission of the dorsal part, rectal temperature and heart rate variability (HRV) were measured from eight Sprague-Dawley rats. The intensities of photon emissions for saline injections, which were used as a control, decreased from 13042+/-71 counts/min at the start of measurements to 8709+/-915 counts/min at 1 h after the injections. In the case with epinephrine injections, the intensity of photon emission reduced slowly from 13361+/-354 counts/min to 11040+/-433 counts/min. Rectal temperature increased in both saline- and epinephrine-injected rats, but one hour after the injections the temperature in the epinephrine case was slightly higher than that in the saline case. The standard deviation of the QRS wave complex interval (RR interval) increased from 1 to 4 (p<0.05) and the spectral ratio of the low frequency component to the high frequency component in the HRV data LF (0.19 approximately 0.74 Hz) / HF (0.78 approximately 2.50 Hz) decreased from 0.81 to 0.26 (p<0.05) in the case of epinephrine injection while no change was found in the case of saline injection. Thus, ultraweak photon emission was closely related to the cardiovascular autonomic activity.
Yoon
Y Z
YZ
Biomedical Physics Laboratory 25-414, School of Physics, Seoul National University, Seoul 151-747, Republic of Korea. dr94@mulli.snu.ac.kr
Kim
J
J
Lee
B C
BC
Kim
Y U
YU
Lee
S K
SK
Soh
K S
KS
D000818:Animals; D004837:Epinephrine / Q000008:administration & dosage*; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology*; D007274:Injections, Intraperitoneal; D008297:Male; D017785:Photons; D051381:Rats; D017207:Rats, Sprague-Dawley; D014915:Whole-Body Counting / Q000379:methods*
D004837:Epinephrine