Rotenoids and isoflavones from Sarcolobus globosus.
Sarcolobus globosus is a medicinal plant growing in mangrove forests in Asia. No constituents from this plant have been reported previously. From the diethyl ether extract of S. globosus a new rotenoid sarcolobin and a new isoflavone sarcolobone, as well as the previously known rotenoids tephrosin, 12aalpha-hydroxydeguelin, 11-hydroxytephrosin, 12a-hydroxyrotenone, 12aalpha-hydroxyrotenone, 6aalpha,12aalpha-12a-hydroxyelliptone, 6a,12a-dehydrodeguelin, 13- homo-13-oxa-6a,12a-dehydrodeguelin, the isoflavone barbigerone and a chromone 6,7-dimethoxy-2,3-dihydrochromone were identified. 6,7-Dimethoxy-2,3-dihydrochromone has not previously been reported as a natural product.
Wangensteen
Helle
H
Department of Pharmacognosy, School of Pharmacy, University of Oslo, Blindern, Oslo, Norway. helle.wangensteen@farmasi.uio.no
Alamgir
Mahiuddin
M
Rajia
Sultana
S
Samuelsen
Anne Berit
AB
Malterud
Karl Egil
KE
D029062:Apocynaceae; D006801:Humans; D007529:Isoflavones / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018547:Plant Stems; D012402:Rotenone / Q000737:chemistry
D007529:Isoflavones; D010936:Plant Extracts; D012402:Rotenone