[Corneal combined amniotic membrane transplantation for early severe alkali chemical injury of the eye].
OBJECTIVE
To investigate the effect of lamella corneal transplantation combined amniotic membrane transplantation for the early severe alkali burns of eyes.


METHODS
Twenty-three eyes with an over second-degree acute corneal alkali injury in 2 weeks were treated by lamella corneal transplantation combined amniotic membrane transplantation. After the operation the patients were treated with an intense and prolonged regimen of topical steroids and topical and systemic vitamin C. All patients were followed up for 6-12 months.


RESULTS
Seven eyes were cornea transparent, 10 semi-transparent, and 6 opaque in the 23 eyes, respectively. The visual acuity of 3 eyes was better than 0.3, that of 5 eyes was between 0.25 to 0.1, and that of the other 15 eyes was below 0.1. No eye was enucleated due to the corneoscleral melting.


CONCLUSIONS
Lamella corneal transplantation combined amniotic membrane transplantation may clear away the necrotic tissues and cells of corneal or conjunctiva, prevent and reduce the complication, and improve the prognosis of the patients.
Xi
Xing-Hu
XH
Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha 410011, China. xhx96@yahoo.com.cn
Cao
Yan-na
YN
Tang
Luo-sheng
LS
Qin
Bo
B
Jiang
De-yong
DY
D000293:Adolescent; D000328:Adult; D000650:Amnion / Q000637:transplantation*; D002057:Burns, Chemical / Q000601:surgery*; D002675:Child, Preschool; D016039:Corneal Transplantation / Q000379:methods; D005126:Eye Burns / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged