Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.
Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
Gardimalla
Hari M R
HM
Department of Chemistry and Biochemistry, Mailcode 4409, Southern Illinois University, Carbondale, IL 62901-4409, USA.
Mandal
Deendayal
D
Stevens
Philip D
PD
Yen
Max
M
Gao
Yong
Y
D002175:Candida / Q000201:enzymology*; D002264:Carboxylic Acids / Q000737:chemistry*; D004800:Enzymes, Immobilized / Q000737:chemistry*; D005290:Ferric Compounds; D007700:Kinetics; D008049:Lipase / Q000737:chemistry*; D049329:Nanostructures; D011422:Propionates / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism
D002264:Carboxylic Acids; D004800:Enzymes, Immobilized; D005290:Ferric Compounds; D011422:Propionates; C000499:ferric oxide; D008049:Lipase; C035775:2-bromopropionic acid