title: Ventricular septal rupture following myocardial infarction. Long-term survival of patients who did not undergo surgery. Single-centre experience.
abstract: Long-term survival is rare in patients not undergoing surgery after post-myocardial infarction ventricular septal rupture. We report our experience of seven patients out of 27, who did not undergo surgery and were followed up for a mean period of 2.8 years. They were evaluated after a mean period of 2.2 months after infarction in our centre. The septal defects measured 9.8 mms on average and the mean left-to-right shunt ratio was 1.98: 1. The mean pulmonary artery, right atrial and left ventricular end diastolic pressures were 28.3 +/- 10.6, 4 +/- 3 and 15.8 +/- 4.8 mm Hg, respectively. Only three out of seven patients had LV aneurysm and all patients had single-vessel disease. Smaller defect size, minimal left-to-right shunt and preserved right ventricular function may be the factors responsible for long-term survival.
authors.affiliation: Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala, India. drharikrishnan@hotmail.com
authors.forename: Harikrishnan
authors.initials: H
authors.lastname: Sivadasan Pillai
authors.forename: Jaganmohan
authors.initials: J
authors.lastname: Tharakan
authors.forename: Thomas
authors.initials: T
authors.lastname: Titus
authors.forename: Ajith
authors.initials: A
authors.lastname: Kumar
authors.forename: Sivasankaran
authors.initials: S
authors.lastname: Sivasubramonian
authors.forename: Kavassery Mahadevan
authors.initials: KM
authors.lastname: Krishnamoorthy
authors.forename: Krishnamoorthy
authors.initials: K
authors.lastname: Kavassery Mahadevan
authors.forename: Santhosh
authors.initials: S
authors.lastname: Dora
authors.forename: Krishnakumar
authors.initials: K
authors.lastname: Nair
authors.forename: Narayanan
authors.initials: N
authors.lastname: Namboodiri
mesh_terms: D000368:Aged; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D016019:Survival Analysis; D017741:Survivors; D018658:Ventricular Septal Rupture / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology