title: Hydroxyl radical generation via photoreduction of a simple pyridine N-oxide by an NADH analogue.
abstract: Photoreduction of pyridine N-oxide, which has a key structure of antitumor agents for hypoxic solid tumors, by 1-benzyl-1,4-dihydronicotinamide in deaerated aprotic media resulted in generation of hydroxyl radical, leading to the oxidation of salicylic acid to 2,3- and 2,5-dihydroxybenzoic acids, and catechol.
authors.affiliation: Redox Regulation Research Group, Research Center for Radiation Safety, National Institute of Radiological Sciences (NIRS), Inage-ku, Chiba, 263-8555, Japan. nakanis@nirs.go.jp
authors.forename: Ikuo
authors.initials: I
authors.lastname: Nakanishi
authors.forename: Chiho
authors.initials: C
authors.lastname: Nishizawa
authors.forename: Kei
authors.initials: K
authors.lastname: Ohkubo
authors.forename: Keizo
authors.initials: K
authors.lastname: Takeshita
authors.forename: Kazuo T
authors.initials: KT
authors.lastname: Suzuki
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Ozawa
authors.forename: Sidney M
authors.initials: SM
authors.lastname: Hecht
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tanno
authors.forename: Shoko
authors.initials: S
authors.lastname: Sueyoshi
authors.forename: Naoki
authors.initials: N
authors.lastname: Miyata
authors.forename: Haruhiro
authors.initials: H
authors.lastname: Okuda
authors.forename: Shunichi
authors.initials: S
authors.lastname: Fukuzumi
authors.forename: Nobuo
authors.initials: N
authors.lastname: Ikota
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Fukuhara