title: Latent period best predicts acetabular cup failure after total hip arthroplasties in radiated hips.
abstract: We retrospectively analyzed the prognostic factors related to the failure of acetabular components after total hip arthroplasties in radiated hips. Eighteen hips from 12 patients who had primary arthroplasties were followed up for a mean of 58 months (range, 20-139 months). The patients' age, total radiation dose, latent period, presence of infection, and the type of the acetabular component were examined as possible predictors of failure using the Cox proportional hazard regression. Multivariate analyses showed that a longer latent period was the most important risk factor for failure, increasing 1.72 times when the latent period was greater than 1 year, after adjusting for other predictors. The latent period might be helpful for clinicians in choosing a treatment method for patients.
  
  
  METHODS
  Prognostic study, Level IV (case series). See the Guidelines for Authors for a complete description of levels of evidence.
authors.affiliation: Department of Orthopaedic Surgery, School of Medicine, Daegu Catholic University Hospital, Daegu, Korea. cmr0426@lycos.co.kr
authors.forename: Myung-Rae
authors.initials: MR
authors.lastname: Cho
authors.forename: Koing-Woo
authors.initials: KW
authors.lastname: Kwun
authors.forename: Duk-Hee
authors.initials: DH
authors.lastname: Lee
authors.forename: Shin-Yoon
authors.initials: SY
authors.lastname: Kim
authors.forename: Jae-Do
authors.initials: JD
authors.lastname: Kim
mesh_terms: D000077:Acetabulum / Q000528:radiation effects; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D019544:Equipment Failure Analysis / Q000379:methods; D019317:Evidence-Based Medicine; D005260:Female; D005270:Femur Head / Q000528:radiation effects; D006622:Hip Prosthesis; D006801:Humans; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000601:surgery*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012189:Retrospective Studies; D013997:Time Factors