Development of pemphigus vulgaris in a patient with vitiligo and Hashimoto's thyroiditis.
Pemphigus vulgaris is an autoimmune blistering disease. An association of pemphigus vulgaris with vitiligo or Hashimoto's thyroiditis has not been reported before. We reported a 38 yr-old female patient with Hashimoto's thyroiditis and vitiligo who eventually developed pemphigus vulgaris on vitiliginous lesions. A genetic predisposition or a local event on vitiliginous skin may be responsible for the development of pemphigus in this patient.
Yalçin
B
B
Ankara Numune Educational and Research Hospital, Dermatology Clinic, Ankara, Turkey. yalcinbasak@yahoo.com
Tamer
E
E
Toy
G G
GG
Oztas
P
P
Alli
N
N
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001379:Azathioprine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007453:Iodide Peroxidase / Q000276:immunology; D010392:Pemphigus / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D016884:Polyendocrinopathies, Autoimmune; D011239:Prednisolone / Q000627:therapeutic use; D013961:Thyroid Gland / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D014820:Vitiligo / Q000150:complications*
D001323:Autoantibodies; C006606:anti-thyroglobulin; D011239:Prednisolone; D007453:Iodide Peroxidase; D001379:Azathioprine