[Chromosome localization and genomic organization of five novel human genes related to cell growth control].
Five novel human genes related to cell growth control were newly isolated and identified by high-throughput functional screening. In this paper, the chromosomal localization of these five genes is reported. Radiation hybrid mapping and in silico mapping,and their genomic organization were analyzed respectively. PP3898 and PP1158 were assigned to chromosome 19p13.3, SP260 and PP753 to chromosome 1q21.1, and HC56 to chromosome 17p13.3. PP3898 contains nineteen exons and eighteen introns, PP1158 seven exons and six introns, SP260 ten exons and nine introns, and HC56 only one exon. The implications of chromosomal localization are discussed.
He
Xiang-Huo
XH
National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032,China. xhhe@mailcity.com
Tan
Wen-Xin
WX
Wang
Jun-Ru
JR
Hu
Jian
J
Zhu
Hong-Xin
HX
Wan
Da-Fang
DF
Gu
Jian-Ren
JR