2-Methyl-(1Z,3E)-butadiene-1,3,4-tricarboxylic acid, "isoprenetricarboxylic acid".
[reaction: see text] The synthesis of the title compound 7 from ethyl glyoxylate and dimethyl and diethyl beta-methylglutaconate is described along with its physical properties that suggest its inability to assume a cis-dienoid structure due to steric hindrance between the methyl and carboxyl groups.
Goren
Mayer B
MB
Laboratory of Applied Mass Spectrometry, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892, USA.
Sokoloski
Edward A
EA
Fales
Henry M
HM
D014233:Tricarboxylic Acids / Q000138:chemical synthesis*
D014233:Tricarboxylic Acids