Human herpesvirus 8--a novel human pathogen.
In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8). This novel herpesvirus has and continues to present challenges to define its scope of involvement in human disease. In this review, aspects of HHV-8 infection are discussed, such as, the human immune response, viral pathogenesis and transmission, viral disease entities, and the virus's epidemiology with an emphasis on HHV-8 diagnostics.
Edelman
Daniel C
DC
Department of Pathology, University of Maryland Baltimore, School of Medicine, Baltimore, Maryland 21201, USA. dedelman@umaryland.edu
D000917:Antibody Formation; D005814:Genes, Viral; D016679:Genome, Viral; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000821:virology*; D019288:Herpesvirus 8, Human / Q000276:immunology / Q000472:pathogenicity* / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular; D007113:Immunity, Innate; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000821:virology