title: Central venous catheter-related infection due to Candida membranaefaciens, a new opportunistic azole-resistant yeast in a cancer patient: a case report and a review of literature.
abstract: An unusual central venous catheter (CVC)-related infection caused by Candida membranaefaciens in a patient with non-Hodgkin's lymphoma is described. Clinical signs and microbiological results observed in this case may support the hypothesis of an emerging CVC-related fungaemia, because of new azole-resistant yeast, successfully treated with liposomal amphotericin B. To date C. membranaefaciens (the teleomorph of Pichia membranaefaciens) has traditionally been considered non-pathogenic and this report seems to be the first case of systemic fungal infection. We believe that another fungus can be added to the list of opportunistic strains.
authors.affiliation: Department of Hematology, University of Florence, Florence, Italy. r.fanci@dac.unifi.it
authors.forename: Rosa
authors.initials: R
authors.lastname: Fanci
authors.forename: Patrizia
authors.initials: P
authors.lastname: Pecile
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000517:prevention & control; D002405:Catheterization, Central Venous; D025141:Drug Resistance, Fungal; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D009894:Opportunistic Infections / Q000382:microbiology* / Q000517:prevention & control; D016459:Prosthesis-Related Infections / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B