title: The chemical constituents of Ligularia pleurocaulis.
abstract: OBJECTIVE
  To study the chemical constituents of the underground part of Ligularia pleurocaulis (Franch.) Hand-Mazz.
  
  
  METHODS
  The dried roots and rhizomes of L. pleurocaulis were extracted with methanol. Isolation and purification were performed by silica gel column chromatography and recrystallization etc. Structures of the pure compounds were established on basis of spectral analysis.
  
  
  RESULTS
  Twelve compounds were obtained from L. pleurocaulis, they were 6-angeloyloxy-furanoligularenone (1), 2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide (2), tiglic acid (3), oleanolic acid (4), lupeol (5), beta-sitosterol (6), daucosterol (7), caffeic acid (8), emodin (9), 7-methoxy-coumarin (10), ferulic acid (11) and 4-hydroxy-2,5-dimethoxy-benzaldehyde (12).
  
  
  CONCLUSIONS
  Compound 1 is a new eremophilane and compound 2 is a new natural compound. All above compounds were obtained for the first time from L. pleurocaulis.
authors.affiliation: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. mianzhang@hotmail.com
authors.forename: Mian
authors.initials: M
authors.lastname: Zhang
authors.forename: Chao-Feng
authors.initials: CF
authors.lastname: Zhang
authors.forename: Zheng-Tao
authors.initials: ZT
authors.lastname: Wang
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D003437:Crotonates / Q000737:chemistry / Q000302:isolation & purification; D045782:Hemiterpenes; D008968:Molecular Conformation; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C522385:2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide; C522384:6-angeloyloxy-furanoligularenone; D003437:Crotonates; D045782:Hemiterpenes; D012717:Sesquiterpenes; D009828:Oleanolic Acid; C009489:tiglic acid