[Membrane microparticles and their roles in the regulation of hematopoiesis - review].
Membrane microparticles are shed from the plasma membrane of most eukaryotic cells when these cells were undergone activation or apoptosis, and released into the extracellular environment. Their composition depends on the cellular origin and processes triggering their formation. Several lines of evidence suggest that membrane microparticles might be able to facilitate cell-cell cross-talk and play an important roles in the regulation of survival, proliferation, differentiation, adhesion and chemotaxis of hematopoietic cells. Here, the components, mechanism of formation and the regulatory roles of membrane microparticles in hematopoiesis were reviewed.
Meng
Er-Hong
EH
Department of Experimental Hematology, Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China.
Wu
Chu-Tse
CT
Wang
Li-Sheng
LS
D021941:Caveolae / Q000378:metabolism / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism / Q000502:physiology*; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D050683:R-SNARE Proteins / Q000378:metabolism / Q000502:physiology*
D050683:R-SNARE Proteins