title: Management, risk factors, and outcomes in recurrent pericarditis.
abstract: Fifty-five of 294 consecutive patients with acute pericarditis had first attacks of recurrent pericarditis and were evaluated and treated according to a management protocol. Corticosteroids were restricted to aspirin contraindication or failure. Colchicine was added in cases of aspirin and prednisone failure and was the treatment of choice for the second and subsequent recurrences. After logistic regression multivariate analysis, only the previous use of corticosteroids (odds ratio 10.35, 95% confidence interval 4.46 to 23.99, p <0.001) was associated with an increased risk for recurrence. After a mean follow-up of 72 months (range 48 to 108), a similar rate of complications was found in patients with or without recurrences.
authors.affiliation: Cardiology Department, Maria Vittoria Hospital, Torino, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Imazio
authors.forename: Brunella
authors.initials: B
authors.lastname: Demichelis
authors.forename: Iris
authors.initials: I
authors.lastname: Parrini
authors.forename: Enrico
authors.initials: E
authors.lastname: Cecchi
authors.forename: Daniela
authors.initials: D
authors.lastname: Demarie
authors.forename: Aldo
authors.initials: A
authors.lastname: Ghisio
authors.forename: Riccardo
authors.initials: R
authors.lastname: Belli
authors.forename: Marco
authors.initials: M
authors.lastname: Bobbio
authors.forename: Rita
authors.initials: R
authors.lastname: Trinchero
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use*; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D010493:Pericarditis / Q000175:diagnosis / Q000188:drug therapy*; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D006074:Gout Suppressants