title: Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia.
abstract: Hyperlipemia rabbit models established with high cholesterol and fat diet were treated with direct moxibustion and medicinal cake-separated moxibustion. The post-treatment plasma 6-keto-prostaglandin F1alpha (6-keto-PGF1alpha) and thromboxane B2 (TXB2) contents were determined by radioimmunoassay. Results indicated that the plasma 6-keto-PGF1alpha content significantly increased, the TXB2 level decreased (P < 0.05) and the TXB2 /6-keto-PGF1alpha ratio also decreased (P < 0.01) in the medicinal cake-separated moxibustion group as compared with those in the model group respectively, but there was no significant difference between the medicinal cake-separated moxibustion group and the direct moxibustion group (P > 0.05), suggesting that both the medicinal cake-separated moxibustion and direct moxibustion can regulate the plasma 6-keto-PGF1alpha and TXB2 contents, and the TXB2/6-keto-PGF1alpha ratio with similar actions, and have a certain protective action on endothelial cells of the aorta in the rabbit of hyperlipemia.
authors.affiliation: Department of Acupuncture & Massage, Hunan College of TCM, Changsha 410007, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Xiaorong
authors.forename: Yan
authors.initials: Y
authors.lastname: Jie
authors.forename: Yue
authors.initials: Y
authors.lastname: Zenghui
authors.forename: Shen
authors.initials: S
authors.lastname: Jing
authors.forename: Lin
authors.initials: L
authors.lastname: Yaping
authors.forename: Yi
authors.initials: Y
authors.lastname: Shouxiang
authors.forename: Cao
authors.initials: C
authors.lastname: Xiangping
mesh_terms: D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood*; D000818:Animals; D005260:Female; D006949:Hyperlipidemias / Q000097:blood / Q000628:therapy*; D008297:Male; D009071:Moxibustion / Q000379:methods; D011817:Rabbits; D011863:Radioimmunoassay; D013929:Thromboxane B2 / Q000097:blood*
chemical_list: D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha