title: [Pulmonary cryptococcosis: analysis of nine cases].
abstract: OBJECTIVE
  To investigate the diagnosis and treatment of pulmonary cryptococcosis.
  
  
  METHODS
  A total of 9 cases of pulmonary cryptococcosis, diagnosed at Sir Run Run Shaw Hospital of Zhejiang University from January 2002 to August 2004, identified by pathological examinations, were retrospectively studied.
  
  
  RESULTS
  The patients consisted of 7 males and 2 females aged from 28 to 69 years. Pulmonary nodules, either solitary or multiple, present in 8 of the 9 cases, were the most common CT finding. The diagnosis was confirmed in all cases by pathological study. The lung specimens of 5 cases were obtained by CT guided transthoracic needle aspiration lung biopsy, and these 5 cases were treated with fluconazole, after 0.5 - 1 year of follow-up, the pulmonary lesion essentially vanished. The other 4 cases were confirmed after surgery.
  
  
  CONCLUSIONS
  Most pulmonary cryptococcosis presented as pulmonary nodules or masses on CT, either solitary or multiple. Pathology was essential to the diagnosis. Fluconazole is active against cryptococcus neoformans, and appears to be effective in the treatment.
authors.affiliation: Department of Respiratory Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China.
authors.forename: Ke-jing
authors.initials: KJ
authors.lastname: Ying
authors.forename: Li-bin
authors.initials: LB
authors.lastname: Jiang
authors.forename: En-guo
authors.initials: EG
authors.lastname: Chen
authors.forename: Wu-jun
authors.initials: WJ
authors.lastname: Hong
authors.forename: Mei
authors.initials: M
authors.lastname: Jin
mesh_terms: D000328:Adult; D000368:Aged; D003453:Cryptococcosis / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies