title: [Pathogens and drug resistance of nosocomial pneumonia after intracranial surgery].
abstract: OBJECTIVE
  To determine the antimicrobial resistance and bacterial distribution of nosocomial pneumonia in neurosurgical patients.
  
  
  METHODS
  We analyzed and counted the result of sputum culture, drug sensibilities test, and the rate of nosocomial pneumonia after intracranial surgery of all the patients in the Department of in Neurosurgery our hospital in 2002.
  
  
  RESULTS
  The rate of nosocomial pneumonia after intracranial surgery was 6.2%. The first 5 strains were pseudomonas aeruginosa, acinetobacter, enterobacteriaceae, klebsiella, and staphylococcus epidermidis. Statistics of drug sensibility test suggested:the rate of ampicillin and cefuroxime resistance was over 83%. Gram-negative bacterium was the first sensitive to sulperazon and imipenem. Gram-positive bacterium was the first sensitive to vancomycin, ampicillin/sulbactam and rifampicin.
  
  
  CONCLUSIONS
  The rate of neurosurgical infection was high. The most common pathogens were gram-negative bacteria. Drug resistance was serious.
authors.affiliation: Department of Respiration Xiangya Hospital, Central South Unversity, Changsha 410078, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Meng
authors.forename: Wei
authors.initials: W
authors.lastname: Xie
authors.forename: An-Hua
authors.initials: AH
authors.lastname: Wu
authors.forename: Cheng-Ping
authors.initials: CP
authors.lastname: Hu
authors.forename: Yan-Jin
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000668:Ampicillin Resistance; D001921:Brain / Q000601:surgery*; D002444:Cefuroxime / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects
chemical_list: D002444:Cefuroxime