Effects of Ginkgo biloba on haemostatic factors and inflammation in chronic peritoneal dialysis patients.
Ginkgo biloba extract decreased plasma D-dimer concentration, a marker of intravascular coagulation, in chronic peritoneal dialysis patients. Blood levels of fibrinogen, von Willebrand factor, hs-CRP, albumin and liver enzyme levels were not significantly changed. No bleeding episode was reported. These results suggest that Ginkgo biloba extract was effective in partially reversing the thrombogenic coagulation profile without increasing the risk of bleeding.
Kim
Su Hee
SH
Department of Internal Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Lee
Eun Kyoung
EK
Chang
Jai Won
JW
Min
Won Ki
WK
Chi
Hyun Sook
HS
Kim
Soon Bae
SB
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000925:Anticoagulants / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001779:Blood Coagulation Factors / Q000187:drug effects; D005260:Female; D020441:Ginkgo biloba; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D001779:Blood Coagulation Factors; D010936:Plant Extracts