Less is more: how reduced activity reflects stronger recognition.
The mechanisms of recognition involve reductions of activity in the medial temporal lobe. This preview discusses recent fMRI and MEG data from Gonsalves et al. (this issue of Neuron) that provide some of the strongest evidence to date demonstrating that reduced medial temporal activity is correlated with stronger recognition of items in humans. This result provides an important test of theories of recognition memory function based on previous neuroimaging and unit recording data.
Stern
Chantal E
CE
Department of Psychology, Center for Memory and Brain, Program in Neuroscience, Boston University, Boston, Massachusetts 02215, USA.
Hasselmo
Michael E
ME
D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008568:Memory / Q000502:physiology*; D008959:Models, Neurological; D021641:Recognition, Psychology / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*