The TaqIA polymorphism linked to the DRD2 gene is related to lower attention and less inhibitory control in alcoholic patients.
The TaqIA polymorphism linked to the DRD2 gene has been associated with alcoholism. The aim of this work is to study attention and inhibitory control as per the continuous performance test and the stop task in a sample of 50 Spanish male alcoholic patients split into two groups according to the presence of the TaqIA1 allele in their genotype. Our results show that alcoholics carrying the TaqIA1 allele present lower sustained attention and less inhibitory control than those patients without such allele.
Rodríguez-Jiménez
R
R
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041 Madrid, Spain. mjimenez.hdoc@salud.madrid.org
Avila
C
C
Ponce
G
G
Ibáñez
M I
MI
Rubio
G
G
Jiménez-Arriero
M A
MA
Ampuero
I
I
Ramos
J A
JA
Hoenicka
J
J
Palomo
T
T
D000328:Adult; D000437:Alcoholism / Q000235:genetics*; D000483:Alleles; D001288:Attention; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D013030:Spain; D000095383:Trace Amine-Associated Receptors
D017448:Receptors, Dopamine D2; D043562:Receptors, G-Protein-Coupled; D000095383:Trace Amine-Associated Receptors