New oleanene glycosides from the leaves of Acanthopanax japonicus.
The structures of 6 new oleanene glycosides (1--6) isolated from the leaves of Acanthopanax japonicus FRANCH et. SAVART (Araliaceae) were elucidated by mass, 1D, and 2D NMR spectroscopy. The structures of 1--6 were established as 28-O-[alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl] ester of 3beta,23-dihydroxy-olean-12-en-28,29-dioic acid, 3beta,30-dihydroxy-olean-12-en-23,28-dioic acid, 3beta,29-dihydroxy-olean-12-en-23,28-dioic acid (=dianic aicd), 3beta-dihydroxy-olean-12-en-23,28-dioic acid (=gypsogenic acid), 3beta,29-dihydroxy-23-oxo-olean-12-en-28-oic acid, and 3beta-hydroxy-23-oxo-olean-12-en-28,29-dioic acid, designated acanjaposide D (1), E (2), F (3), G (4), H (5), and I (6), respectively.
Park
Sang-Yong
SY
Department of Pharmacognosy, College of Pharmacy, KyungHee University;1 Hoegidong, Dondaemungu, Seoul 130-702, Korea. dragonpsy@khu.ac.jp
Yook
Chang-Soo
CS
Nohara
Toshihiro
T
D002236:Carbohydrate Conformation; D002241:Carbohydrates / Q000737:chemistry; D028001:Eleutherococcus / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment
D002241:Carbohydrates; D006027:Glycosides; C505015:acanjaposide; D009828:Oleanolic Acid