title: [Comparison of clinical efficacy between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia].
abstract: OBJECTIVE
  To compare the clinical efficacy and safety between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia.
  
  
  METHODS
  86 patients with oligoasthenospermia were received at our clinic of andrology. They were randomly divided into group A and B. The patients in group A received Huorongbushen 48 g daily for 3 months, and the other patients in group B were given indomethacin 50 mg daily for 3 months. The sperm parameters of the patients were analyzed by computer-assisted sperm analysis system before and after treatment.
  
  
  RESULTS
  Patients of group A were significantly improved in sperm concentration, forward sperm motility, total sperm motility, straight line velocity and average path velocity. Patients of group B remained unimproved in sperm concentration and were significantly improved in other sperm parameters. The patients in group A reported a significantly higher sperm concentration than that in group B. There was no significant difference between group A and B in other sperm parameters.
  
  
  CONCLUSIONS
  Compared with indomethacin, Huorongbushen is efficacious for oligoasthenospermia with lower side effects.
authors.affiliation: Department of Andrology, Nanjing General Hospital of Nanjing Command, Nanjing, Jiangsu 21002, China.
authors.forename: Shao-Peng
authors.initials: SP
authors.lastname: Sun
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Shang
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Huang
mesh_terms: D000328:Adult; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D008517:Phytotherapy; D013076:Sperm Count; D013081:Sperm Motility
chemical_list: D016861:Cyclooxygenase Inhibitors; D004365:Drugs, Chinese Herbal; D007213:Indomethacin