title: [Research on hemostatic effect of total saponins of yinfenglun].
abstract: OBJECTIVE
  To research the hemostatic effect of total saponins of Yinfenglun.
  
  
  METHODS
  Bleeding time and volume were deteminded in mice after tails being cut. Clotting times were researched on mice, rats and dogs. Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, PT, KPTT and ELT.
  
  
  RESULTS
  TSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system,and had no effect of antifibrinolysis.
  
  
  CONCLUSIONS
  There were obvious hemostatic effect of total saponins of Yinfenglun.
authors.affiliation: Anhui College of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Dai-Yin
authors.initials: DY
authors.lastname: Peng
authors.forename: Qing-Yun
authors.initials: QY
authors.lastname: Liu
authors.forename: Min
authors.initials: M
authors.lastname: Dai
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Zi
authors.forename: Xian-Xiang
authors.initials: XX
authors.lastname: Xu
mesh_terms: D000818:Animals; D001760:Bleeding Time; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006490:Hemostatics / Q000494:pharmacology*; D019686:Lamiaceae / Q000737:chemistry; D008297:Male; D051379:Mice; D010314:Partial Thromboplastin Time; D035261:Plant Components, Aerial / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011517:Prothrombin Time; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D014914:Whole Blood Coagulation Time
chemical_list: D004365:Drugs, Chinese Herbal; D006490:Hemostatics; D012503:Saponins