title: Understanding velocity of sound in trabecular bone via computer simulations.
abstract: Osteoporosis is a condition characterized by low bone mass and micro-architectural deterioration leading to non-traumatic fractures of the skeleton. It is a potentially debilitating condition especially for senior citizens. There is growing interest for quantitative ultrasound to measure bone mineral density. However, understanding of ultrasound-bone interaction is limited. Simulating ultrasound propagation of bone can help us better understand ultrasound-bone interaction and provide insight into bone architecture. In this study a mathematical model for the propagation of sound in bone is presented. Results demonstrate the suitability of the proposed modeling approach and the model's capability to reproduce conditions in the lab.
authors.affiliation: Department of Decision Sciences and MIS, John Molson School of Business, Concordia University, 1455 De Maisonneuve Building, Montreal, Queb., Canada H3G 1M8. rsinfo@sympatico.ca
authors.forename: Raafat George
authors.initials: RG
authors.lastname: Saadé
authors.forename: George
authors.initials: G
authors.lastname: Tsoukas
authors.forename: John
authors.initials: J
authors.lastname: Caminis
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D005269:Femur / Q000033:anatomy & histology* / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008953:Models, Anatomic; D008962:Models, Theoretical; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D012756:Sheep; D012984:Software; D013016:Sound; D014465:Ultrasonics; D014463:Ultrasonography