title: [Randomized controlled study of S (+) -ismer of ibuprofen supporsitory].
abstract: OBJECTIVE
  To evaluate the efficacy and safety of S (+) - ismer of ibuprofen supporsitory.
  
  
  METHODS
  One hundred and three cases of postopterative pain and 60 cases of fever, altogether 163 patients were randomly divided into 2 groups: S (+) -ismer of ibuprofen supporsitory treatment group (one supporsitory per day for 3 days) and ibuprofen supporsitory treatment group (one supporsitory per day for 3 days). The therapeutic effect was assessed and the side-effects were observed between the 2 groups.
  
  
  RESULTS
  After being given medicine in the first 4 hours, pain intensity difference, pain remission degree and the dropped level of fever in S (+) -ismer of ibuprofen were all bigger than those of the ibuprofen supporsitory treatment group. There was no difference in side-effects between the 2 groups.
  
  
  CONCLUSIONS
  Therapeutic effect of S (+) -ismer of ibuprofen supporsitory is definite, whose action appears more quickly and stronger and it has fewer side-effects than those of ibuprofen supporsitory.
authors.affiliation: Department of Rheumatology, Xiangya Hospital, Central South University Changsha, China.
authors.forename: Yun-Hui
authors.initials: YH
authors.lastname: You
authors.forename: Cai-Ling
authors.initials: CL
authors.lastname: Wu
authors.forename: Jie-Sheng
authors.initials: JS
authors.lastname: Gao
authors.forename: An-Lan
authors.initials: AL
authors.lastname: Huang
authors.forename: Hui
authors.initials: H
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005334:Fever / Q000188:drug therapy*; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D013237:Stereoisomerism; D013488:Suppositories
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013488:Suppositories; D007052:Ibuprofen