Prorocentin, a new polyketide from the marine dinoflagellate Prorocentrum lima.
Prorocentin (1), isolated from an okadaic acid-producing organism, Prorocentrum lima, possessed all-trans trienes, an epoxide, as well as the 6/6/6-trans-fused/spiro-linked polyether ring moieties. The unique structure supports the proposed cyclization mechanism, polyene formation, epoxidation, and cyclization, of marine polyether toxins. The relative stereostructure was determined on the basis of spectral data. [structure: see text]
Lu
Chung-Kuang
CK
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan. cklu@nmmba.gov.tw
Chou
Hong-Nong
HN
Lee
Ching-Kuo
CK
Lee
Tzong-Huei
TH
D000818:Animals; D003500:Cyclization; D004141:Dinoflagellida / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019319:Okadaic Acid / Q000378:metabolism
D005663:Furans; D018942:Macrolides; C511474:prorocentin; D019319:Okadaic Acid