The clinico-radiologic properties of deep small basal ganglia infarction: lacune or small striatocapsular infarction?
OBJECTIVE
Deep small basal ganglia infarction (DSBI) cannot be clearly classified as either lacune or striatocapsular infarction by their sizes only. We tried to elucidate clinical and other properties of DSBI to understand better in pathophysiology of ischemic lesion of basal ganglia.


METHODS
We analyzed 36 patients with acute ischemic lesion of basal ganglia with the size varying from 1.5 to 3 cm in maximal diameters. We assessed clinical features, laboratory data, risk factors of stroke, and radiologic findings such as MRI and MR angiography.


RESULTS
Patients with DSBI could be largely divided into two distinctive groups, small infarction with cortical sign (SICS) and lacunar syndrome (LS) according to their presence of cortical manifestations. Total of 11 patients were in SICS group and they showed cortical manifestations such as eyeball deviation, visual field defect, aphasia and neglect. They also showed severer non-cortical neurologic deficit compared with LS group. Whereas LS group showed various MRA patterns, 7 patients of SICS group (63.6%) showed proximal MCA stenosis in MRA.


CONCLUSIONS
We found that many patients with DSBI could have the features of either lacune or striatocapsular infarction. Although they have similar morphologic characteristics but they are presumed to have different pathophysiologic mechanism.
Jung
San
S
Department of Neurology, Hallym University College of Medicine, Seoul, South Korea. neurojs@hallym.ac.kr
Hwang
Sung-Hee
SH
Kwon
Seok-Beom
SB
Yu
Kyung-Ho
KH
Lee
Byung-Chul
BC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001037:Aphasia / Q000503:physiopathology; D020144:Basal Ganglia Cerebrovascular Disease / Q000000981:diagnostic imaging* / Q000473:pathology*; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000209:etiology; D010468:Perceptual Disorders / Q000503:physiopathology; D011859:Radiography; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000000981:diagnostic imaging / Q000473:pathology; D014794:Visual Fields / Q000502:physiology