Central nervous system paracoccidioidomycosis: an overview.
Paracoccidioidomycosis (PCM) is an infectious disease, endemic to subtropical areas of Central and South America, caused by the dimorphic fungus Paracoccidioides brasiliensis. It is a chronic disease, mostly affecting adult males, with a mean patient age of 44 years. Central nervous system involvement (CNS PCM) has been found in 13% of the patients with systemic disease. We reviewed the clinical presentation, diagnosis techniques and treatments for CNS PCM.
de Almeida
Sérgio Monteiro
SM
Hospital de Clínicas--UFPR, Especialidade de Neurologia. Rua General Carneiro, PR-Brazil. sdealmeida@popmail.ucsd.edu
D000328:Adult; D000818:Animals; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D010228:Paracoccidioides; D010229:Paracoccidioidomycosis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy