title: Does posterior fossa decompression improve oculomotor and vestibulo-ocular manifestations in Chiari 1 malformation?
abstract: BACKGROUND
  Oculomotor and vestibulo-ocular manifestations are associated with Chiari 1 malformation. Reports of the results of decompression of CM1 in resolution of these manifestations are limited.
  
  
  METHODS
  A retrospective review of case notes were undertaken from Jan 1998 to March 2003 of all the cases undergoing posterior fossa decompressions by the senior author. Forty patients were identified of which 12 had oculomotor and vestibulo-ocular manifestations.
  
  
  RESULTS
  Oculomotor and vestibulo-ocular symptoms were present in seven patients and eleven patients had clinical signs. There were only 2 patients who had symptoms and no objective findings. There was complete resolution of oculomotor and vestibulo-ocular manifestations in 8/12 patients and partial improvement in another one, leading to improvement in 9/12 patients. The mean time span to complete resolution was 15.5 months (range 3-71 months).
  
  
  CONCLUSIONS
  Posterior fossa decompression appears to be highly effective in causing complete resolution of disabling oculomotor and vestibule-ocular manifestations in most cases of CM1.
authors.affiliation: Hurstwood Park Neurological Centre, Haywards Heath, West Sussex, UK. lizettelieb@gmail.com
authors.forename: W A
authors.initials: WA
authors.lastname: Liebenberg
authors.forename: H
authors.initials: H
authors.lastname: Georges
authors.forename: A K
authors.initials: AK
authors.lastname: Demetriades
authors.forename: C
authors.initials: C
authors.lastname: Hardwidge
mesh_terms: D000293:Adolescent; D000328:Adult; D001139:Arnold-Chiari Malformation / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D001933:Brain Stem / Q000473:pathology / Q000503:physiopathology; D002531:Cerebellum / Q000473:pathology / Q000503:physiopathology; D003388:Cranial Fossa, Posterior / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D019299:Decompression, Surgical / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000706:statistics & numerical data*; D009759:Nystagmus, Pathologic / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D015835:Ocular Motility Disorders / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D015837:Vestibular Diseases / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*