title: Biotransformation of racemic diisophorone by Cephalosporium aphidicola and Neurospora crassa.
abstract: Racemic diisophorone (500 mg) was converted by Cephalosporium aphidicola and Neurospora crassa over 10 days at 25 degrees C to 8beta-hydroxydiisophorone in yields of 10% (52 mg) and 20% (103 mg), respectively. The structure was established by IR, specific rotation, mass spectral, 1D and 2D-NMR studies.
authors.affiliation: Department of Chemistry, Osmangazi University, 26480, Eskinşehir, Turkey. ikiran@ogu.edu.tr
authors.forename: Ismail
authors.initials: I
authors.lastname: Kiran
authors.forename: Tamer
authors.initials: T
authors.lastname: Akar
authors.forename: Asli
authors.initials: A
authors.lastname: Gorgulu
authors.forename: Cavit
authors.initials: C
authors.lastname: Kazaz
mesh_terms: D000164:Acremonium / Q000254:growth & development*; D001711:Biotransformation; D003512:Cyclohexanones / Q000378:metabolism*; D009492:Neurospora crassa / Q000254:growth & development*; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; C005940:isophorone