title: No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females.
abstract: Monoamine oxidase A (MAO-A) is an enzyme involved in the metabolism of monoamine neurotransmitters such as dopamine, serotonin, and noradrenaline in the brain. Previous studies have demonstrated a significant association between MAO-A gene polymorphism and personality traits in males. The purpose of the present study was to examine this association in females. The subjects were 219 healthy Japanese females. We genotyped a variable number of tandem repeats located upstream of the MAO-A gene. Personality traits were assessed using the Temperament and Character Inventory (TCI). There was no association between any personality trait and MAO-A genotype. The present results do not support the hypothesis that MAO-A gene polymorphism is related to certain personality traits in females.
authors.affiliation: Department of Psychology and Human Developmental Sciences, Nagoya University, Graduate School of Education and Human Development, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Hakamata
authors.forename: Nagahide
authors.initials: N
authors.lastname: Takahashi
authors.forename: Ryoko
authors.initials: R
authors.lastname: Ishihara
authors.forename: Shinichi
authors.initials: S
authors.lastname: Saito
authors.forename: Norio
authors.initials: N
authors.lastname: Ozaki
authors.forename: Shuji
authors.initials: S
authors.lastname: Honjo
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ono
authors.forename: Toshiya
authors.initials: T
authors.lastname: Inada
mesh_terms: D000293:Adolescent; D000328:Adult; D004252:DNA Mutational Analysis / Q000379:methods; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008175:Lung Neoplasms / Q000201:enzymology* / Q000453:epidemiology* / Q000235:genetics; D008297:Male; D008995:Monoamine Oxidase / Q000235:genetics*; D010551:Personality / Q000235:genetics*; D010555:Personality Inventory; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics; D019655:Quantitative Trait, Heritable; D013223:Statistics as Topic
chemical_list: D008995:Monoamine Oxidase