title: Controlled spacing of cationic gold nanoparticles by nanocrown RNA.
abstract: Using atomic force microscopy, we describe the linear arrangement of cationic gold nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the regular spacing of nanoparticles is controlled by the RNA architecture acting as nanocrown scaffoldings. Thus, precise positioning of molecular components can be accomplished with RNA not only through electrostatic but also via size and shape recognitions.
authors.affiliation: Department of Chemistry and Biochemistry, University of California - Santa Barbara, 93106-9510, USA.
authors.forename: Alexey Y
authors.initials: AY
authors.lastname: Koyfman
authors.forename: Gary
authors.initials: G
authors.lastname: Braun
authors.forename: Sergei
authors.initials: S
authors.lastname: Magonov
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Chworos
authors.forename: Norbert O
authors.initials: NO
authors.lastname: Reich
authors.forename: Luc
authors.initials: L
authors.lastname: Jaeger
mesh_terms: D002412:Cations; D047248:Crown Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D008956:Models, Chemical; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size; D011506:Proteins / Q000737:chemistry; D012313:RNA / Q000737:chemistry*; D013860:Thiocholine / Q000737:chemistry
chemical_list: D002412:Cations; D047248:Crown Compounds; D011506:Proteins; D013860:Thiocholine; D012313:RNA; D006046:Gold