title: An autopsy case of imipramine poisoning.
abstract: We present a fatal imipramine poisoning. Quantitative analysis of imipramine and its metabolite, desipramine, was performed by high-performance liquid chromatography. The concentrations of imipramine and desipramine were 18.67 microg/mL and 6.21 microg/mL in heart blood and 6.90 microg/mL and 1.77 microg/mL in the femoral venous blood, respectively. We concluded that the cause of death was due to imipramine poisoning.
authors.affiliation: Department of Legal Medicine, Hyogo College of Medicine, Hyogo, Japan. kinochin@hyo-med.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Tadaaki
authors.initials: T
authors.lastname: Taniguchi
authors.forename: Akira
authors.initials: A
authors.lastname: Kubota
authors.forename: Minori
authors.initials: M
authors.lastname: Nishiguchi
authors.forename: Harumi
authors.initials: H
authors.lastname: Ouchi
authors.forename: Takako
authors.initials: T
authors.lastname: Minami
authors.forename: Takao
authors.initials: T
authors.lastname: Utsumi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Motomura
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nagasaki
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Ameno
authors.forename: Shigeru
authors.initials: S
authors.lastname: Hishida
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000097:blood / Q000506:poisoning*; D001344:Autopsy; D002423:Cause of Death; D002851:Chromatography, High Pressure Liquid; D003891:Desipramine / Q000097:blood / Q000378:metabolism; D062787:Drug Overdose / Q000401:mortality; D005260:Female; D005554:Forensic Medicine; D049429:Forensic Pathology; D006801:Humans; D007099:Imipramine / Q000097:blood / Q000378:metabolism / Q000506:poisoning*; D007564:Japan; D007684:Kidney Tubules / Q000473:pathology; D008875:Middle Aged
chemical_list: D000929:Antidepressive Agents, Tricyclic; D007099:Imipramine; D003891:Desipramine