title: The lung at maximal exercise: insights from comparative physiology.
abstract: Horses are bred selectively for aerobic performance and have extraordinarily high maximal oxygen consumption, approximately double the mass-specific value for human athletes. Pulmonary limitations to exercise performance are well described in these animals, including exercise-induced arterial hypoxemia and exercise-induced pulmonary hemorrhage. In human athletes, pulmonary limitations are recognized increasingly as affecting athletic performance. Potential pulmonary limitations during maximal exercise are compared in human and equine athletes.
authors.affiliation: Division of Physiology, Department of Medicine, University of California--San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. shopkins@ucsd.edu
authors.forename: Susan R
authors.initials: SR
authors.lastname: Hopkins
mesh_terms: D015444:Exercise / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000502:physiology* / Q000503:physiopathology; D012143:Respiratory Physiological Phenomena