In vivo characterization of titanium implants coated with synthetic hydroxyapatite by electrophoresis.
This study compared in vivo the performances of commercially pure titanium (cp Ti) screw dental implants either uncoated or coated with synthetic hydroxyapatite (HA) by electrophoresis. The HA coating was characterized by scanning electron microscopy, energy dispersive spectroscopy (EDS) and Fourier-transform infrared (FT-IR) spectroscopy. Well-adhered carbonated-hydroxyapatite layers (4- to-8-microm-thick) were obtained. In vivo tests were carried out by insertion of both uncoated and HA-coated implants into rabbit tibiae for 8 or 12 weeks. Histomorphometric analysis was performed by scanning electron microscopy with the aid of image-processing software. Results showed significantly greater bone-implant contact for HA-coated implants (p<0.05) than cp Ti implants. Comparison of bone content inside the screw implants showed no significant differences (p>0.05) between both types of implants, although cp Ti had numerically higher percentage of bone content than HA-coated implants. In conclusion, the HA-coated implants had better performance regarding the bone-implant contact area than the uncoated implants; coating by electrophoresis proved to be a valuable process to coat metallic implants with an osteoconductive material such as hydroxyapatite.
Costa
Cristina de Almeida
Cde A
Department of Metallurgical and Materials Engineering, COPPE, UFRJ, Rio de Janeiro, RJ, Brazil.
Sena
Lídia Agata
LA
Pinto
Marcelo
M
Muller
Carlos Alberto
CA
Cavalcanti
José Henrique Lima
JH
Soares
Glória de Almeida
Gde A
D000818:Animals; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D017886:Durapatite; D004586:Electrophoresis; D005260:Female; D020007:Implants, Experimental; D008297:Male; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration; D011817:Rabbits; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D018709:Statistics, Nonparametric; D013977:Tibia; D014025:Titanium
D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D017886:Durapatite; D014025:Titanium