title: Intracavitary cardiac metastasis and pulmonary tumor emboli of choriocarcinoma: the first case diagnosed and treated without surgical intervention.
abstract: BACKGROUND
  Choriocarcinoma mostly metastasizes to lung parenchyma. Its pulmonary tumor embolism and cardiac metastasis are very rarely encountered, of which antemortem diagnosis is even more rare.
  
  
  METHODS
  To our knowledge, we present the first case of intracavitary cardiac metastasis and pulmonary tumor emboli of choriocarcinoma diagnosed and treated without any surgical intervention. Multi-agent chemotherapy led to almost complete regression of cardiac and pulmonary lesions and normalization of beta-hCG levels.
  
  
  CONCLUSIONS
  Cardiac metastasis of choriocarcinoma must be kept in mind for cases of cardiac mass in reproductive age women, especially when history and clinical presentation are suggestive for gestational trophoblastic disease. As the tumor is highly sensitive, chemotherapy together with biochemical and radiological monitoring constitutes an effective treatment modality if cardiopulmonary functions are not deteriorating.
authors.affiliation: Ankara University, Medical Faculty Department of Obstetrics and Gynecology, Gezegen S. No: 7/4, Büyükesat, Ankara, Turkey. eclamptic2000@yahoo.com
authors.forename: Elif Aylin
authors.initials: EA
authors.lastname: Bozaci
authors.forename: Salih
authors.initials: S
authors.lastname: Taşkin
authors.forename: Ozlem
authors.initials: O
authors.lastname: Gürkan
authors.forename: Cetin
authors.initials: C
authors.lastname: Atasoy
authors.forename: Zinet Gül
authors.initials: ZG
authors.lastname: Ersoy
authors.forename: Selim
authors.initials: S
authors.lastname: Erekul
authors.forename: Numan
authors.initials: N
authors.lastname: Numanoğlu
authors.forename: Firat
authors.initials: F
authors.lastname: Ortaç
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002822:Choriocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D005260:Female; D006338:Heart Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008875:Middle Aged