Gastric outlet obstruction and cutaneous metastasis in adenocarcinoid tumor of stomach - unusual presentations with cytologic and ultra structural findings.
Neuroendocrine tumors, including carcinoids account for less than 1% of gastric tumors. Various subtypes of gastric carcinoids have been reported earlier. The present case deals with two unusual presentations, diagnosis and course of a gastric neuroendocrine tumor in an adult patient. A 35-years-old male initially presented with gastric outlet obstruction for an antral growth in the emergency ward. He underwent radical gastrectomy and was diagnosed with a gastric carcinoid tumor, on histopathology. After 6 months, he developed hepatic along with nodular cutaneous lesions over the scalp. Aspiration cytology (FNAC) from these metastatic lesions showed two distinct cell types with rosette formation. Ultrastructural findings showed neurosecretory granules in some cells. Subsequently, he underwent 2 cycles of chemotherapy. After a total duration of 9 months, he finally succumbed to the disease. We present a case of a gastric adenocarcinoid tumor, with 2 rare presentations. The metastatic lesions exhibited neuroendocrine features on cytology and electron microscopy.
Rekhi
Bharat
B
Institute of Pathology, ICMR and Safdarjung Hospital, New Delhi, India. rekhib@hotmail.com
Saxena
Sunita
S
D000328:Adult; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D017219:Gastric Outlet Obstruction / Q000209:etiology; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary; D008297:Male; D008854:Microscopy, Electron; D009362:Neoplasm Metastasis; D018358:Neuroendocrine Tumors / Q000150:complications / Q000175:diagnosis* / Q000556:secondary / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000648:ultrastructure; D013274:Stomach Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure