Synthesis and total assignment of 1H and 13C NMR spectra of new oxoisoaporphines by long-range heteronuclear correlations.
The new oxoisoaporphines 7H-dibenzo[de,h]quinolin-7-one, 5-methoxy-7H-dibenzo[de,h]quinolin-7-one, 5-methoxy-6-hydroxy-7H-dibenzo[de,h]quinolin-7-one, 5-hydroxy-7H-dibenzo[de,h]quinolin-7-one and 5-methoxy-6H-dibenzo[de,h]quinolin-6-one were prepared either by oxidation of their 2,3-dihydro derivatives or by heating (2'-(3,4-dihydro-6,7-dimethoxyisoquinolin-1'-yl)phenyl)methylbenzoate with an acetic acid/sulfuric acid mixture at 100 degrees C. The structures were confirmed and 1H and 13C NMR spectra were completely assigned using two-dimensional NMR techniques.
Sobarzo-Sánchez
Eduardo
E
Department of Organic Chemistry and C.S.I.C. Associated Unit, Faculty of Chemistry, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain. esobarzo@usc.es
De la Fuente
Julio
J
Castedo
Luis
L
D001060:Aporphines / Q000737:chemistry*; D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011522:Protons
D001060:Aporphines; D002247:Carbon Isotopes; D011522:Protons