[Comparison of clinical efficacy between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia].
OBJECTIVE
To compare the clinical efficacy and safety between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia.


METHODS
86 patients with oligoasthenospermia were received at our clinic of andrology. They were randomly divided into group A and B. The patients in group A received Huorongbushen 48 g daily for 3 months, and the other patients in group B were given indomethacin 50 mg daily for 3 months. The sperm parameters of the patients were analyzed by computer-assisted sperm analysis system before and after treatment.


RESULTS
Patients of group A were significantly improved in sperm concentration, forward sperm motility, total sperm motility, straight line velocity and average path velocity. Patients of group B remained unimproved in sperm concentration and were significantly improved in other sperm parameters. The patients in group A reported a significantly higher sperm concentration than that in group B. There was no significant difference between group A and B in other sperm parameters.


CONCLUSIONS
Compared with indomethacin, Huorongbushen is efficacious for oligoasthenospermia with lower side effects.
Sun
Shao-Peng
SP
Department of Andrology, Nanjing General Hospital of Nanjing Command, Nanjing, Jiangsu 21002, China.
Shang
Xue-Jun
XJ
Huang
Yu-Feng
YF
D000328:Adult; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D008517:Phytotherapy; D013076:Sperm Count; D013081:Sperm Motility
D016861:Cyclooxygenase Inhibitors; D004365:Drugs, Chinese Herbal; D007213:Indomethacin