title: [The lactobacilli-protection system of pregnant women--efficient prevention of premature births by early detection of disturbances].
abstract: BACKGROUND
  The most frequent cause of preventable early premature births (< 32 + 0 gestational weeks) is urogenital tract infection (UTI). Screening for UTI and Chlamydia are now standard examinations. Detection of ascending genital infections, especially bacterial vaginosis, plays an ever-increasing role. Lactobacilli, which produce, e. g., lactic acid, H2O2, biosurfactants and coaggregation molecules, are particularly important for the vaginal biosystem. Some evaluations suggest that early diagnosis and therapy within this "lactobacilli-protection system" apparently leads to better results in the prevention of prematurity. Our screening recommendations for the pregnant patient comprise vaginal pH measurements both at the regular prenatal care visits and particularly the self measurement within the framework of our Self-Care Program.
  
  
  METHODS
  140 participating women were questioned for a second time. The data were compiled by the patients themselves.
  
  
  RESULTS
  Due to elevated pH values, 21% of the women consulted their physician earlier than foreseen. Diagnoses: In 46% there was a disturbance of the vaginal milieu, in 4% bacterial vaginosis, in 33% Candida infection and in 21% "everything was OK". In spite of self-measured normal pH values in 25% of the patients the physician diagnosed the following: 25% disturbance of the vaginal milieu, 7% bacterial vaginosis, 32% infection with other bacteria (mainly Streptococci) and 50% Candida infection.
  
  
  CONCLUSIONS
  Elevated pH values (measured by the patient) seem to indicate much more often a disturbance of vaginal milieu rather than an already existing bacterial vaginosis. Further investigations are necessary. The chances to treat vaginal disturbances--before a concrete infection is diagnosed--seem to be better for participants in the Self-Care Program.
authors.affiliation: Universitätsmedizin Berlin. info@saling-institut.de
authors.forename: E
authors.initials: E
authors.lastname: Saling
authors.forename: M
authors.initials: M
authors.lastname: Schreiber
mesh_terms: D002181:Candidiasis, Vulvovaginal / Q000382:microbiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007778:Lactobacillus / Q000502:physiology*; D007752:Obstetric Labor, Premature / Q000382:microbiology / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology / Q000517:prevention & control*; D011296:Prenatal Diagnosis; D011933:Reagent Kits, Diagnostic; D012307:Risk Factors; D012648:Self Care; D014621:Vagina / Q000382:microbiology; D014627:Vaginitis / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D011933:Reagent Kits, Diagnostic