title: Synthesis, characterisation and biological evaluation of lanthanide(III) complexes with 3-acetylcoumarin-o-aminobenzoylhydrazone (ACAB).
abstract: Lanthanide(III) complexes of the general formula [Ln(ACAB)(2)(NO(3))(2)(H(2)O)(2)].NO(3).H(2)O where Ln=La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III) and Y(III), ACAB=3-acetylcoumarin-o-aminobenzoylhydrazone have been isolated and characterised based on elemental analyses, molar conductance, IR, (1)H- and (13)C-NMR, UV, TG/DTA and EPR spectral studies. The ligand behaves in bidentate fashion coordinating through hydrazide >C=O and nitrogen of >C=N. A coordination number of ten is assigned to the complexes. Antibacterial and Antifungal studies indicate an enhancement of activity of the ligand on complexation.
authors.affiliation: Department of Chemistry, Karnatak University; Dharwad-580 003, India. kbgudasi@rediffmail.com
authors.forename: Kalagouda B
authors.initials: KB
authors.lastname: Gudasi
authors.forename: Rashmi V
authors.initials: RV
authors.lastname: Shenoy
authors.forename: Ramesh S
authors.initials: RS
authors.lastname: Vadavi
authors.forename: Manjula S
authors.initials: MS
authors.lastname: Patil
authors.forename: Siddappa A
authors.initials: SA
authors.lastname: Patil
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D003374:Coumarins / Q000737:chemistry* / Q000494:pharmacology*; D004055:Differential Thermal Analysis; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D005658:Fungi / Q000187:drug effects; D006835:Hydrazones / Q000737:chemistry* / Q000494:pharmacology*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: C504997:3-acetylcoumarin-o-aminobenzoylhydrazone; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D003374:Coumarins; D006835:Hydrazones; D028581:Lanthanoid Series Elements; D008024:Ligands; D004121:Dimethyl Sulfoxide