Dendridine A, a bis-indole alkaloid from a marine sponge Dictyodendrilla Species.
A unique C2-symmetrical 4,4'-bis(7-hydroxy)indole alkaloid, dendridine A (1), was isolated from an Okinawan marine sponge Dictyodendrilla sp., and the structure was elucidated by spectroscopic data. Dendridine A (1) exhibited antibacterial and antifungal activities.
Tsuda
Masashi
M
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Takahashi
Yohei
Y
Fromont
Jane
J
Mikami
Yuzuru
Y
Kobayashi
Jun'ichi
J
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D026121:Indole Alkaloids; C504640:dendridine A