Infiltrative breast cancer during pregnancy and conservative surgery.
Mastectomy is considered as the standard therapy for gestational breast cancer. Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, respectively. No local recurrences occurred with a median follow-up time of 87 months. Among the 10 patients treated with conservative surgery, 3 chose therapeutic abortion and 7 opted to continue their pregnancy. Concerning these 7 fetuses, there were no congenital anomalies, nor growth restriction. All children were normal physically and neurologically. We concluded that conservative breast surgery may be an alternative to mastectomy in the treatment of gestational breast cancer and is safe for the fetus.
Annane
Kadour
K
Service de Gynécologie-Obstétrique, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Bellocq
Jean-Pierre
JP
Brettes
Jean-Philippe
JP
Mathelin
Carole
C
D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015412:Mastectomy, Segmental; D009367:Neoplasm Staging; D010865:Pilot Projects; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D016896:Treatment Outcome