title: Lambda integrase: armed for recombination.
abstract: Bacteriophage lambda moves its viral genome into and out of the bacterial chromosome using site-specific recombination. Crystal structures of reaction intermediates in this recombination pathway provide exciting new snapshots of full length lambda integrase interacting with both core and regulatory DNA elements.
authors.affiliation: Department of Biochemistry & Biophysics, Howard Hughes Medical Institute University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. vanduyne@mail.med.upenn.edu
authors.forename: Gregory D
authors.initials: GD
authors.lastname: Van Duyne
mesh_terms: D010582:Bacteriophage lambda / Q000201:enzymology* / Q000235:genetics*; D004247:DNA / Q000378:metabolism*; D019426:Integrases / Q000378:metabolism*; D008954:Models, Biological; D011995:Recombination, Genetic / Q000235:genetics*; D016662:Virus Integration / Q000502:physiology*
chemical_list: D004247:DNA; D019426:Integrases