Carcinoma erysipelatoides from squamous cell carcinoma of unknown origin.
Carcinoma erysipelatoides, also known as inflammatory metastatic carcinoma, is a rare form of cutaneous metastasis from a malignancy. The characteristic histopathological finding is metastatic tumour cells inside the dermal lymphatic ducts. It is frequently observed in patients with breast carcinoma as well as adenocarcinoma of pancreas, rectum, lung, ovary and parotid gland. We present a 66-year-old man diagnosed to have metastatic squamous cell carcinoma by aspiration cytology from an enlarged neck lymph node and a core biopsy of a left axillary mass. He subsequently received radiotherapy; however, due to intolerance to erythema and swelling on local irradiated skin, radiotherapy was deferred. Skin lesions on upper chest and neck area, consisting of erythematous induration with telangiectasia and tenderness, progressed slowly and were treated as cellulitis. The erythema remained stationary with antibiotic treatment. Skin biopsy shows poorly differentiated squamous carcinoma cells within dermis and dilated dermal vessels.
Yu
K-J
KJ
Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Lee
H-E
HE
Ho
H-C
HC
Lee
J C
JC
Chang
J W-C
JW
Hong
H-S
HS
Yang
C-H
CH
D000368:Aged; D001365:Axilla; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D004890:Erythema / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009333:Neck; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*