The JAK2V617F mutation is acquired secondary to the predisposing alteration in familial polycythaemia vera.
Cario
Holger
H
Goerttler
Philipp S
PS
Steimle
Cordula
C
Levine
Ross L
RL
Pahl
Heike L
HL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004252:DNA Mutational Analysis; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D053614:Janus Kinase 2; D008297:Male; D008875:Middle Aged; D008957:Models, Genetic; D009196:Myeloproliferative Disorders / Q000235:genetics; D010375:Pedigree; D011087:Polycythemia Vera / Q000235:genetics*; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*
D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; C507924:JAK2 protein, human; D053614:Janus Kinase 2