title: Outcome of patients with fortuitous prostate cancer after radical cystoprostatectomy for bladder cancer.
abstract: OBJECTIVE
  To analyze the outcome of patients after fortuitous diagnosis of prostate cancer (PCa) on cystoprostatectomy (CPT) specimen.
  
  
  METHODS
  The medical charts of 141 male patients who underwent radical CPT for urothelial cell carcinoma of the bladder between january 1995 and april 2000 were retrospectively reviewed. None of the patients had preoperative clinical or biological suspicion of PCa.
  
  
  RESULTS
  Pathological examination of the CPT specimens showed PCa in 20 patients (14.2%). Of these, 6 had a microfocal PCa, 10 had a pT2a tumour, 2 had a pT2b tumour, and 2 had a pT3a tumour. The Gleason score was < or =5 in 5 cases, 6 in 13 cases, and 7 in 2 cases. Two patients were lost to follow-up. Ten patients died of bladder cancer after a median follow-up of 13 months. Eight patients remained free of disease after a median follow-up of 64.5 months. None of the 20 patients experienced PCa recurrence during follow-up.
  
  
  CONCLUSIONS
  In our experience, the rate of unsuspected PCa on cystoprostatectomy specimens was 14.2%. The majority of these PCas were organ-confined, and there was no PCa recurrence during follow-up.
authors.affiliation: Department of Urology, Cochin Hospital, Service d'Urologie, Paris, France.
authors.forename: Nicolas Barry
authors.initials: NB
authors.lastname: Delongchamps
authors.forename: Kaili
authors.initials: K
authors.lastname: Mao
authors.forename: Hang
authors.initials: H
authors.lastname: Theng
authors.forename: Marc
authors.initials: M
authors.lastname: Zerbib
authors.forename: Bernard
authors.initials: B
authors.lastname: Debré
authors.forename: Michaël
authors.initials: M
authors.lastname: Peyromaure
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D015331:Cohort Studies; D015653:Cystectomy / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D011379:Prognosis; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D018570:Risk Assessment; D015996:Survival Rate; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*