[Clinical cure for acute methanol poisoning].
OBJECTIVE
To analyze the treatment of 42 patients with acute methanol poisoning because of drinking alcohol containing methanol.


METHODS
Clinical data of 42 cases of methanol poisoning were collected and analyzed. Methanol concentration in drinking alcohol and blood was determined by gas chromatography (GC). National standard for occupational medicine (GBZ53-2002) was used to diagnose the cases.


RESULTS
The methanol concentration in the alcohol was 16% approximately 46%. 42 Patients (40 males, 2 females), at age of 46.1 (22 approximately 80), took 588.1 ml (50 approximately 2,000 ml) of the alcohol. The average methanol concentration in blood was 1.61 mmol/L (0.03 approximately 23.60 mmol/L). According to clinical diagnosis, there were 17 observed cases, 9 mild acute toxication, and 16 severe acute toxication. Among them, 35 (83.3%) patients were recovered, 2 (4.8%) blind, 4 (9.5%) with neuropsychic sequela and 1 (2.4%) dead after adopting 8 cure measures.


CONCLUSIONS
To start using emergency plan for public health events suddenly happened, designate a special treatment hospital, clear blood methanol as soon as possible, correct acidosis, adequately administer folacin and hormone, protect optic nerve and retina, and take comprehensive symptomatic treatment as well as strict monitoring are the keys of clinical cure.
Jiang
Chao-qiang
CQ
Guangzhou No. 12 Hospital, Guangzhou 510620, China.
Wu
Yi-xing
YX
Liu
Wei-wei
WW
Cheng
Jian-xin
JX
Li
Xiao-qiang
XQ
Liu
Yi-min
YM
Zhou
Gang
G
Zhou
Xuan
X
Zhang
Cheng
C
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D000432:Methanol / Q000506:poisoning*; D008875:Middle Aged; D011041:Poisoning / Q000628:therapy; D015980:Public Health Practice
D000432:Methanol