In vitro antifungal susceptibilities of Sporothrix schenckii in two growth phases.
We have determined the antifungal susceptibilities of 34 clinical isolates of the dimorphic fungus Sporothrix schenckii to 11 drugs using a microdilution method. In general, the type of growth phase (mycelial or yeast) and the temperature of incubation (30 or 35 degrees C) exerted a significant influence on the MICs.
Trilles
Luciana
L
Serviço de Micologia Médica, Instituto de Pesquisa Clínica Evandro Chagas, FIOCRUZ, Rio de Janeiro, Brazil.
Fernández-Torres
Belkys
B
Dos Santos Lazéra
Márcia
M
Wanke
Bodo
B
de Oliveira Schubach
Armando
A
de Almeida Paes
Rodrigo
R
Inza
Isabel
I
Guarro
Josep
J
D000935:Antifungal Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D013175:Sporothrix / Q000187:drug effects* / Q000254:growth & development*; D013174:Sporotrichosis / Q000382:microbiology; D013696:Temperature
D000935:Antifungal Agents