title: CT of the chest and abdomen in patients with newly diagnosed head and neck squamous cell carcinoma.
abstract: BACKGROUND
  The benefits of CT scanning of the chest and abdomen as a routine screening method for patients with newly diagnosed head and neck squamous cell carcinoma (HNSCC) remain unclear.
  
  
  METHODS
  Consecutive patients with a primary HNSCC (T classification, T2-T4) and or regionally metastatic disease (ie, N+) were eligible for inclusion. Patients who were considered incurable and patients with recurrent disease were excluded. CT scans of the chest and abdomen were performed.
  
  
  RESULTS
  We examined 100 patients. Two patients had pulmonary metastases at presentation. An occult aortic aneurysm required surgical repair before anticancer therapy in one patient. In many patients, nonspecific CT findings warranted further examinations or close follow-up. The abdominal CT was negative for metastatic HNSCC in all patients.
  
  
  CONCLUSIONS
  Routine CT screening of the chest and abdomen resulted in upstaging of disease in two patients (2%) and altered the treatment approach in three patients (3%). Abdominal CT does not seem beneficial in patients with previously untreated HNSCC. Chest CT is not indicated routinely.
authors.affiliation: Department of Otorhinolaryngology, Helsinki University Central Hospital, P. O. Box 220, FIN-00029 HUCH, Helsinki, Finland. harri.keski-santti@hus.fi
authors.forename: Harri T
authors.initials: HT
authors.lastname: Keski-Säntti
authors.forename: Antti T O
authors.initials: AT
authors.lastname: Markkola
authors.forename: Antti A
authors.initials: AA
authors.lastname: Mäkitie
authors.forename: Leif J J
authors.initials: LJ
authors.lastname: Bäck
authors.forename: Timo S
authors.initials: TS
authors.lastname: Atula
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed