Long-term visual pathology in children with significant perinatal complications.
Eye research in infants who experience significant perinatal complications has been restricted to evaluation of structural ocular disease and spatial vision, and results show that these aspects of vision are at increased risk for abnormal or delayed development. To expand upon previous work, a battery of 17 vision tests was employed to assess, comprehensively, long-term outcome of functional vision. Seventy-six children (38 males, 38 females), between the corrected ages of 2 years 11 months and 10 years 2 months (mean 6y 6mo) with various significant complications (e.g. very preterm birth, bronchopulmonary dysplasia, intraventricular hemorrhage) were compared to normally developing, age-matched control children (n = 61; mean age 7y 1mo) on measures of visual acuity, contrast sensitivity, stereoacuity, peripheral vision, color vision, astigmatism, and binocular alignment. Results showed that at-risk children had more test results that fell within the suspect or abnormal range. At-risk children also had a slightly higher incidence of ocular disorders (e.g. strabismus) and refractive error. These data imply that children who experienced significant perinatal risk factors are at risk for long-term deficits of functional vision. However, most of these deficits appear to be relatively mild.
Adams
Russell J
RJ
Department of Psychology/Pediatrics, Memorial University, St John's, NF, Canada A1B 3X9. michelem@mun.ca
Hall
Heather L
HL
Courage
Mary L
ML
D001997:Bronchopulmonary Dysplasia / Q000175:diagnosis / Q000453:epidemiology; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000453:epidemiology; D002552:Cerebral Ventricles; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D007744:Obstetric Labor Complications / Q000175:diagnosis* / Q000453:epidemiology; D007752:Obstetric Labor, Premature / Q000175:diagnosis* / Q000453:epidemiology; D011247:Pregnancy; D012030:Refractive Errors / Q000175:diagnosis / Q000453:epidemiology; D012307:Risk Factors; D013223:Statistics as Topic; D013285:Strabismus / Q000175:diagnosis / Q000453:epidemiology; D014786:Vision Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*