Solitary fibrous tumor of the liver.
We report a new case of benign solitary fibrous tumor (SFT) of the liver. A 65-year-old man presented to our unit with upper right abdominal discomfort. On examination abdominal distension was present and palpation showed a large firm mass in the right hypochondrium and epigastrium. The patient's past medical history was not significant and laboratory tests were normal. Ultrasonography and computed tomography showed a large tumor, 20 cm in diameter, in the right lobe of the liver. An extended right hepatectomy was performed. The tumor measured 30 x 28 x 14 cm and weighed 4725 g. Microscopic evaluation showed a benign SFT of the liver with tumor cells typically positive for vimentin and CD34. The postoperative course was uneventful, and the patient is alive 30 months after surgery. This is a rare neoplasm of mesenchymal origin that occasionally involves the liver in adult patients. Most SFTs are benign, but some may have malignant histological features and recur locally or metastasize. Because of their rarity, overall experience has not been significant and little has been published concerning this tumor, Including the present one, 28 cases have been reported in the English literature. Surgery is the mainstay of treatment. Little can be said about the benefits of adjuvant radiochemotherapy in these patients. As SFT of the liver is often a benign neoplasm, chemotherapy or radiotherapy should not be necessary, and should be reserved for when resection is incomplete and/or histological examination reveals features of malignancy. Surgeons must be aware of SFT of the liver, and this neoplasm should be included in the differential diagnosis of a single large hepatic mass.
Vennarecci
Giovanni
G
Divisione di Chirurgia Digestiva e dei Trapianti, Istituto Regina Elena, Via E. Chianesi 53, 00144 Rome, Italy.
Ettorre
Giuseppe Maria
GM
Giovannelli
Luca
L
Del Nonno
Franca
F
Perracchio
Letizia
L
Visca
Paolo
P
Corazza
Valerio
V
Vidiri
Antonello
A
Visco
Giuseppe
G
Santoro
Eugenio
E
D000368:Aged; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology*