Auditory thalamus integrates visual inputs into behavioral gains.
By binding multisensory signals, we get robust percepts and respond to our surroundings more correctly and quickly. How and where does the brain link cross-modal sensory information to produce such behavioral advantages? The classical role of sensory thalamus is to relay modality-specific information to the cortex. Here we find that, in the rat thalamus, visual cues influence auditory responses, which have two distinct components: an early phasic one followed by a late gradual buildup that peaks before reward. Although both bimodal presentation and reward value had similar effects on behavioral performance, the cross-modal effect on neural activity showed unique temporal dynamics: it affected the amplitude of the early component and starting level of the late component, whereas reward value affected only the slope of the late component. These results demonstrate that cross-modal cueing modulates gain in the sensory thalamus, potentially providing a priming influence on the choice of an optimal behavior.
Komura
Yutaka
Y
Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology, 1-1-1 Umezono, Tsukuba 305-8568, Japan.
Tamura
Ryoi
R
Uwano
Teruko
T
Nishijo
Hisao
H
Ono
Taketoshi
T
D000161:Acoustic Stimulation / Q000379:methods; D000200:Action Potentials / Q000502:physiology; D000704:Analysis of Variance; D000818:Animals; D001307:Auditory Perception / Q000502:physiology*; D001522:Behavior, Animal; D001931:Brain Mapping; D007839:Functional Laterality / Q000502:physiology; D008297:Male; D008960:Models, Psychological; D010775:Photic Stimulation / Q000379:methods; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000502:physiology; D012201:Reward; D017603:Signal Detection, Psychological / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*; D013788:Thalamus / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*