title: Comment on "Nanorobotics control design: a collective behavior approach for medicine".
abstract: The limitations on nanorobot design and activity imposed by Brownian motion events, communication problems, and the nature of the intercellular space are discussed. It is shown that severe problems exist for a nanorobot designed to enter tissues for therapeutic purposes when it is smaller than about 1 microm in any one of its dimensions.
authors.affiliation: Centre for Cell Engineering, University of Glasgow, Glasgow G12 8QQ, UK. A.Curtis@bio.gla.ac.uk
authors.forename: A S G
authors.initials: AS
authors.lastname: Curtis
mesh_terms: D000465:Algorithms; D001698:Biomedical Engineering / Q000295:instrumentation* / Q000379:methods / Q000639:trends; D003198:Computer Simulation; D017076:Computer-Aided Design; D003299:Cooperative Behavior; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005246:Feedback; D008846:Micromanipulation / Q000295:instrumentation* / Q000379:methods / Q000639:trends; D008962:Models, Theoretical; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods / Q000639:trends; D012371:Robotics / Q000295:instrumentation* / Q000379:methods / Q000639:trends