title: Experimental infection of calves with Pasteurella multocida Serovar A: 3 isolated in Japan.
abstract: Pasteurella multocida, serovar A: 3, selected by pathogenicity in mice from among 10 strains isolated from pneumonic lesions of calves, was adjusted to 10(7), 10(8) and 10(10) colony-forming units (CFU), and inoculated intratracheally into four calves. All calves showed pyrexia and had lungs with congestion and hepatization. Inoculation with 10(10) CFU of bacteria produced respiratory symptoms and abscesses in lungs. This information will aid elucidation of the pathogenicity of P. multocida and the development of vaccines.
authors.affiliation: Kyoto Biken Laboratories, Japan.
authors.forename: Kayoko
authors.initials: K
authors.lastname: Ishiguro
authors.forename: Takashi
authors.initials: T
authors.lastname: Kitajima
authors.forename: Sei
authors.initials: S
authors.lastname: Kubota
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Amimoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Oda
authors.forename: Shinichi
authors.initials: S
authors.lastname: Fukuyama
authors.forename: Yukio
authors.initials: Y
authors.lastname: Shimizu
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology* / Q000473:pathology*; D007564:Japan; D008168:Lung / Q000473:pathology; D051379:Mice; D010326:Pasteurella Infections / Q000473:pathology / Q000662:veterinary*; D016979:Pasteurella multocida / Q000472:pathogenicity*; D013045:Species Specificity