title: Optical fiber-based sensors: application to chemical biology.
abstract: Optical fibers have been used to develop sensors based on nucleic acids and cells. Sensors employing DNA probes have been developed for various genomics applications and microbial pathogen detection. Live cell-based sensors have enabled the monitoring of environmental toxins, and have been used for fundamental studies on populations of individual cells. Both single-core optical fiber sensors and optical fiber sensor arrays have been used for sensing based on nucleic acids and live cells.
authors.affiliation: Department of Chemistry, Tufts University, Medford, MA 02155, USA.
authors.forename: Kathryn L
authors.initials: KL
authors.lastname: Brogan
authors.forename: David R
authors.initials: DR
authors.lastname: Walt
mesh_terms: D015374:Biosensing Techniques; D002477:Cells; D009696:Nucleic Acids / Q000737:chemistry*; D055095:Optics and Photonics
chemical_list: D009696:Nucleic Acids