Gold(I)-catalyzed synthesis of highly substituted furans.
Cationic triphenylphosphinegold(I) complexes are excellent catalysts for a cascade reaction of propargyl-Claisen rearrangement and heterocyclization to synthesize tri- and tetrasubstituted furans. Starting from easily accessed propargyl vinyl ethers, the furans are obtained in 72-99% yield. [reaction: see text]
Suhre
Michael H
MH
Lehrstuhl für Organische Chemie I, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching, Germany.
Reif
Michael
M
Kirsch
Stefan F
SF