[The endocrine activity and clinical characteristics of benign ovarian fibro-epithelial tumors].
OBJECTIVE
To investigate the endocrine activity and clinical characteristics of benign ovarian fibro-epithelial tumors.


METHODS
A retrospective analysis was done on 16 cases of benign fibro-epithelial tumor collected from the department of obstetrics and gynecology, Peking Union Medical College Hospital from 1981 to 2000.


RESULTS
The examinations of endocrine activity was measured in 15 cases. Serum estradiol and follicle-stimulating hormone levels in 4 cases, it was (166.5 +/- 83.0) pmol/L and (39.4 +/- 12.6) IU/L respectively; low to moderate level of estrogen influence was observed in 8 cases by vaginal cytology; endometrium proliferation was observed in 10/15 cases by pathological examination.


RESULTS
post-menopausal vaginal bleeding in 10 cases, lower abdominal recessive pain in 3 cases, pelvic mass in all of the 16 cases with both pelvic examination and ultrasonography.


CONCLUSIONS
Most of the benign fibro-epithelial tumor have endocrine activity and related clinical manifestations.
Yu
Q
Q
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Dong
R
R
He
F
F
D015746:Abdominal Pain / Q000209:etiology; D000232:Adenofibroma / Q000097:blood* / Q000473:pathology; D004717:Endometrium / Q000473:pathology; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood* / Q000473:pathology; D017698:Postmenopause; D012189:Retrospective Studies; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging / Q000473:pathology
D004967:Estrogens; D004958:Estradiol; D005640:Follicle Stimulating Hormone