[T2N1M0 non-small cell lung cancer: surgery and prognostic factors].
OBJECTIVE
To determine the prognostic factors for the survival in a group of patients operated on for a non-small cell lung cancer classified as T2N1M0.


METHODS
Two hundred sixteen patients treated exclusively with surgery were studied. Kaplan-Meier survival and Cox multivariable regression analyses were used.


RESULTS
The overall survival rate was 39.8% at 5 years and 29.9% at 10 years. Sex, age, presence or absence of symptoms, type of resection, number, and location of affected lymph nodes had no effect on survival. Tumor size (P=.04) and histologic type (P=.03) did significantly affect prognosis. Both variables entered into the Cox multivariable regression model.


CONCLUSIONS
Patients operated on for non-small cell lung cancer classified as T2N1M0 have an overall probability of 5-year survival of approximately 40%. However, the prognosis for this group of patients is heterogeneous: in our study it was affected by the histologic type (45.5% for squamous cell and 25% for non-squamous cell cancers) and tumor size (53% for tumors with a diameter of <or=3 cm, 45% for tumors between 3.1 and 5 cm, and 29% for a tumor diameter >5 cm).
Padilla
J
J
Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, España. jpadilla@comv.es
Calvo
V
V
Peñalver
J C
JC
Jordá
C
C
Escrivá
J
J
Cerón
J
J
García Zarza
A
A
Pastor
J
J
Blasco
E
E
D000328:Adult; D000368:Aged; D002283:Carcinoma, Bronchogenic / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D016016:Proportional Hazards Models; D016019:Survival Analysis