title: Physostigmine for the acute treatment of restless legs syndrome.
abstract: We present a case report of an acute episode of restless legs syndrome that interfered with the performance of a diagnostic imaging procedure of the cervical spine. The patient had a 19-yr history of restless leg syndrome with periodic limb movements during sleep. Treatment with additional sedation and opioids did not alleviate the leg movements. IV administration of 1 mg of physostigmine eradicated all extraneous leg motion.
authors.affiliation: Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, South Carolina.
authors.forename: Calvert C
authors.initials: CC
authors.lastname: Alpert
authors.forename: D Patrick
authors.initials: DP
authors.lastname: Tobin
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Dierdorf
mesh_terms: D000368:Aged; D002800:Cholinesterase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D016292:Procedural Sedation; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D010830:Physostigmine / Q000008:administration & dosage / Q000627:therapeutic use*; D012148:Restless Legs Syndrome / Q000188:drug therapy*; D013122:Spinal Diseases / Q000150:complications / Q000175:diagnosis
chemical_list: D002800:Cholinesterase Inhibitors; D010830:Physostigmine