title: [Can US-guided vacuum-assisted biopsies be an alternative to diagnostic surgery in cases of non-diagnostic core needle biopsy?].
abstract: OBJECTIVE
  To assess US-guided vacuum-assisted biopsies in the diagnosis of suspicious sonographic breast lesions after non-diagnostic core needle biopsies (CNB).
  
  
  METHODS
  Retrospective study of 42 females with suspicious breast lesions at US. CNB previously performed were non-diagnostic. Because of the larger sample size, vacuum-assisted biopsies were performed, instead of surgical biopsy.
  
  
  RESULTS
  Vacuum-assisted biopsies showed 32 benign lesions. Histologic examination of the CNB showed non-specific fibrous tissue in 43% of cases as opposed to 7.1% for vacuum-assisted biopsies. The latter provided a more specific diagnosis (mainly fibrocystic breast disease). From a total of 4 lesions that were suspicious at CNB, 3 were diagnosed as malignancies after vacuum-assisted biopsy and one case was a "borderline" lesion. Three additional malignant and three additional borderline lesions were diagnosed on vacuum-assisted biopsies. In 11 cases, surgical excision was performed, and all diagnoses from vacuum-assisted biopsies were confirmed at microscopy, except in one case where it was underestimated (ADH versus DCIS).
  
  
  CONCLUSIONS
  US-guided vacuum-assisted biopsy is a reliable technique. Because it provides more tissue than CNB, it can be an alternative to diagnostic surgery after non-diagnostic CNB. Indeed, it allows confirmation of the diagnosis and provides a more specific diagnosis of benign lesions. With regards to malignant and borderline lesions, it avoids the risk of false-negative CNB and overlooking carcinomas.
authors.affiliation: Service de Radiologie, Hôpital Porte-Madeleine, CHR d'Orleans, BP 2439, 45032 Orleans 1.
authors.forename: E
authors.initials: E
authors.lastname: Carpentier
authors.forename: A
authors.initials: A
authors.lastname: Maruani
authors.forename: P
authors.initials: P
authors.lastname: Michenet
authors.forename: C
authors.initials: C
authors.lastname: Bonneau
authors.forename: P
authors.initials: P
authors.lastname: Degand
authors.forename: P
authors.initials: P
authors.lastname: Lebas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods*; D044963:Biopsy, Fine-Needle; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000473:pathology; D018275:Carcinoma, Lobular / Q000473:pathology; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D008413:Mastitis / Q000473:pathology; D008875:Middle Aged; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional; D014618:Vacuum