[Heredity and evolution of ADAM].
ADAM (a disintegrin and metalloproteinase), or named MDC (metalloproteinase/disintegrin/cysteine-rich) is a family of glycoproteins in cell surface, which was found in recent years and consists of a signal peptide, a propetide, a metalloproteinase, a disintegrin, a cysteine-rich domain, and an epidermal growth factor (EGF)-like domain, a transmembrane region, and a cytoplasmic tail. The research results about their origin, heredity, evolution and evolutionary relationship are summarized in this paper.
Xu
Cun-Shuan
CS
College of Life Sciences, Henan Normal University, Xinxiang, Henan 453002, China.
Zhang
Wei-Min
WM