title: Total laparoscopic hysterectomy versus total abdominal hysterectomy: cohort review of patients with uterine neoplasia.
abstract: OBJECTIVE
  Retrospective analysis of surgico-pathologic data comparing total laparoscopic hysterectomy (TLH) with total abdominal hysterectomy (TAH) patients with uterine neoplasia.
  
  
  METHODS
  We conducted a chart abstraction of all patients undergoing hysterectomy for uterine neoplasia from September 1996 to November 2004. Patients were assigned to undergo the abdominal or laparoscopic approach based on established clinical safety criteria.
  
  
  RESULTS
  The study included 105 patients, 29 with TAH and 76 with TLH. TAH patients were older (68 vs. 61, P=0.021); however, both groups had similar body mass indexes (31) and parities (1.6). Controlling for age, surgical duration was similar (152 minutes). Average blood loss was higher for TAH, (504 vs. 138 mL, P<0.001). Hospital stays were significantly longer for patients with TAH than for those with TLH (5.4 vs. 1.8 days, P<0.0001). Uterine weight was greater (197 vs. 135 g, P=0.008) and myometrial invasion deeper in the TAH group (48% outer half vs. 17%, P=0.001). More patients had Stage II or higher disease in the TAH group (35% vs. 17%, P=0.038). More TAH patients needed node dissection (79% vs. 28%, P<.001). Node yields from dissections of 23 TAH cases and 21 laparoscopic cases were similar (17 nodes). Total and reoperative complications from TAH versus TLH were not statistically different in our small sample (14.3 vs. 5.2% total, NS; 10.3 vs. 2.6% reoperative). One conversion was necessary from laparoscopy to laparotomy for unsuspected bulky metastatic disease.
  
  
  CONCLUSIONS
  Based on clinical selection criteria, TLH performed for endometrial pathology has few complications and is well tolerated by select patients. The advantages are less blood loss and a shorter length of hospital stay for qualified patients.
authors.affiliation: Gynecologic Oncology Associates, Palo Alto, California, USA. ohanlan@AOL.com
authors.forename: Katherine A
authors.initials: KA
authors.lastname: O'Hanlan
authors.forename: Gloria Shining
authors.initials: GS
authors.lastname: Huang
authors.forename: Anne-Caroline
authors.initials: AC
authors.lastname: Garnier
authors.forename: Suzanne L
authors.initials: SL
authors.lastname: Dibble
authors.forename: Mirjam L
authors.initials: ML
authors.lastname: Reuland
authors.forename: Lisbeth
authors.initials: L
authors.lastname: Lopez
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Pinto
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D015992:Body Mass Index; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D015907:Hysteroscopy; D007902:Length of Stay / Q000706:statistics & numerical data; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012449:Safety; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000601:surgery*