title: Report of aggressive renal cell carcinoma in two patients with von Hippel-Lindau disease.
abstract: Renal cell carcinoma is relatively common in patients with von Hippel-Lindau disease, yet characteristically follows a less aggressive course compared with sporadic renal cell carcinoma. We report on 2 patients with von Hippel-Lindau disease and atypically aggressive renal tumors. In these patients, more rigorous screening guidelines may help to identify the more aggressive variants.
authors.affiliation: Department of Urology, Emory University School of Medicine, Atlanta, Georgia, USA.
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Healy
authors.forename: Nedra
authors.initials: N
authors.lastname: Hood
authors.forename: Kenneth
authors.initials: K
authors.lastname: Ogan
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000209:etiology*; D006801:Humans; D007680:Kidney Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D006623:von Hippel-Lindau Disease / Q000150:complications*