title: Sleep disordered breathing in chronic stroke survivors. A study of the long term follow-up of the SCOPES cohort using home based polysomnography.
abstract: Prevalence of sleep-disordered breathing (SDB) (apnea-hypopnea index [AHI] > or = 5) in acute stroke patients ranges between 44% and 95%, compared to the community prevalence, 9 to 35% for women and 8 to 57% for men [age range 30-60 years]. Limited data exists beyond 3 months following stroke. We assessed the prevalence of SDB amongst stroke survivors at 3 years and compared results to data reported in normal and elderly populations. 90/143 eligible stroke survivors from an existing cohort underwent a home based sleep study. Mean age of the 78 subjects with a valid sleep study was 64 years (SD 15). Prevalence of SDB (AHI > or = 5) was 81% (95% CI 72% to 90%) and sleep apnoea syndrome (AHI > or = 5 plus ESS score > or =11) was 20% (95% CI 11% to 29%). Important predictors for AHI > or = 15 were haemorrhagic stroke (aOR12.06 [1.42-102.74]) and stroke severity at 1 month (aOR4.15 [1.05-16.38]). Large case-control studies are needed.
authors.affiliation: National Stroke Research Institute. Level 1 Neurosciences Building, Repatriation Hospital, Heidelberg Heights, Australia. cadilhac@austin.unimelb.edu.au
authors.forename: Dominique A
authors.initials: DA
authors.lastname: Cadilhac
authors.forename: Rachel D
authors.initials: RD
authors.lastname: Thorpe
authors.forename: Dora C
authors.initials: DC
authors.lastname: Pearce
authors.forename: Maree
authors.initials: M
authors.lastname: Barnes
authors.forename: Peter D
authors.initials: PD
authors.lastname: Rochford
authors.forename: Natalie
authors.initials: N
authors.lastname: Tarquinio
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Davis
authors.forename: Geoff A
authors.initials: GA
authors.lastname: Donnan
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Pierce
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003710:Demography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000379:methods*; D015995:Prevalence; D011446:Prospective Studies; D015203:Reproducibility of Results; D012891:Sleep Apnea Syndromes / Q000453:epidemiology* / Q000209:etiology*; D018709:Statistics, Nonparametric; D020521:Stroke / Q000150:complications / Q000453:epidemiology / Q000401:mortality; D011795:Surveys and Questionnaires; D017741:Survivors