title: [Non-neoplastic enlargement of salivary glands: clinico-histologic analysis].
abstract: We carried out a retrospective study on non-neoplastic enlargement of the salivary glands at the Oral Histopathology Diagnostic Center of the Autonomous Metropolitan University at Xochimilco (UAM-Xochimilco) in Mexico during a period of 24 years (1979-2003). From 5,625 biopsies received and analyzed, a total of 461 (8.2%) were non-neoplastic enlargement of the salivary glands; for each case, we registered demographic data as well as clinic characteristics. These lesions were characterized as a heterogeneous group of pathologic entities among which we included local, obstructive, infectious, and immunopathologic lesions. The most frequent lesion was the extravasation cyst in 341 (74%) cases, followed by chronic sialoadenitis and Sjögren's syndrome with 54 (11.7%) and 41 (8.8%) cases, respectively, and at a lesser percentage mucous retention cyst, sialosis, benign lymphoepithelial lesions and those related with sialolytes. Females were affected more frequently; mean age was second to third life decades. These lesions were most frequently localized on inferior labial mucosa.
authors.affiliation: Centro de Diagnóstico de Histopatología Bucal, Universidad Autónoma, Metropolitana-Xochimilco. mgonzal@cueyatl.uam.mx
authors.forename: Martha Beatriz
authors.initials: MB
authors.lastname: González Guevara
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Torres Tejero
authors.forename: Guillermo
authors.initials: G
authors.lastname: Martínez Mata
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003560:Cysts / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012466:Salivary Gland Diseases / Q000378:metabolism / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000378:metabolism / Q000473:pathology; D014987:Xerostomia / Q000378:metabolism / Q000473:pathology