title: [Orbital involvement as the first manifestation of Hand-Schuller-Christian disease. A case report].
abstract: PURPOSE/MATERIAL AND METHOD: To describe the clinical case of a 20-month-old boy with Hand-Schuller-Christian disease. Exophthalmos was the only systemic manifestation evident over a period of at least 6 weeks, but later the triad of exophthalmos with multiple lytic lesions of the skull and diabetes insipidus were present.
  
  
  CONCLUSIONS
  Histiocytosis X should be considered in the differential diagnosis of orbital tumors in children.
authors.affiliation: Hospital General Medina del Campo, Valladolid, Spain. vasensio@hmdc.sacyl.es
authors.forename: V M
authors.initials: VM
authors.lastname: Asensio-Sánchez
authors.forename: M J
authors.initials: MJ
authors.lastname: Calvo-Crespo
mesh_terms: D000367:Age Factors; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000175:diagnosis / Q000209:etiology*; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D013997:Time Factors