[A case of hepatic metastases of ampullary carcinoma which completely responded to intrahepatic infusion of 5-FU with low-dose l-leucovorin].
A 70-year-old man was admitted with an ampullary carcinoma with multiple hepatic metastases. The patient underwent a pancreaticoduodenectomy for control of bleeding from the tumor. Then, low-doses of l-leucovorin (25 mg/body bolus) and 5-FU (500 mg/body/hour) were injected through an injection port every week. After 40 times, CT scanning showed almost a complete response without side effects.
Ishii
Yoshimasa
Y
Dept. of Surgery, Digestive Center, Ohta Nishinouchi Hospital.
Takahashi
Masayasu
M
Yoshida
Sayaka
S
Suzuki
Kota
K
D000368:Aged; D014670:Ampulla of Vater; D004379:Duodenal Neoplasms / Q000473:pathology*; D004386:Duodenum / Q000601:surgery; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D010180:Pancreatectomy
D002955:Leucovorin; D005472:Fluorouracil