An uncommon cause of scleroderma.
The human immunodeficiency virus (HIV) pandemic is nearly 20 years old. HIV infection is characterized by profound immunodeficiency resulting in an increased incidence of opportunistic infections and neoplasms. However, the greatest paradox is the occurrence of certain autoimmune disorders in the setting of HIV. These include diffuse interstitial lymphocytosis syndrome (DILS), reactive arthritis, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). It has also been seen that even in the absence of these well-defined diseases, various rheumatological manifestations such as arthralgias, arthritis, myopathy, vasculitis, and sicca syndrome are commonly associated with HIV. To the best of our knowledge, the association of HIV with scleroderma has not previously been reported.
Sikdar
S
S
Department of Medicine, Maulana Azad Medical College and associated hospitals, New Delhi, India.
Grover
C
C
Kubba
S
S
Yadav
A
A
Sahni
V
V
Aggarwal
G
G
Singh
N P
NP
Agarwal
S K
SK
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D015497:HIV-1 / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D016867:Immunocompromised Host; D019259:Lamivudine / Q000627:therapeutic use; D008875:Middle Aged; D019829:Nevirapine / Q000627:therapeutic use; D013902:Radiography, Thoracic; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000821:virology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015215:Zidovudine / Q000627:therapeutic use
D019380:Anti-HIV Agents; D000935:Antifungal Agents; D019259:Lamivudine; D015215:Zidovudine; D015725:Fluconazole; D019829:Nevirapine