Interdisciplinary research: noradrenergic regulation of adaptive immunity.
To understand the complexity of mechanisms involved in the regulation of adaptive immunity by the sympathetic neurotransmitter norepinephrine and adrenergic receptor stimulation, there must be a rich history of basic science and clinical findings upon which to form hypotheses for testing, as well as a rich supply of individuals trained in two or more disciplines. This review is intended to offer a tour of the past, present, and future discoveries that have been made in the area of adrenergic regulation of adaptive immunity, as well as share a vision of how our field of study will progress years from now, given that every individual who contributes to the interdisciplinary nature of our research is valued. And finally, this review will discuss how the lessons from the past can help us to attain a vision of interdisciplinary research for the future.
Sanders
Virginia M
VM
Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH, USA. sanders.302@osu.edu
D000222:Adaptation, Physiological / Q000276:immunology; D000320:Adrenergic Fibers / Q000378:metabolism*; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D005544:Forecasting; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007107:Immune System / Q000294:innervation* / Q000378:metabolism; D033183:Interdisciplinary Communication; D015213:Neuroimmunomodulation / Q000502:physiology*; D009638:Norepinephrine / Q000378:metabolism*; D011598:Psychoneuroimmunology / Q000266:history*; D011941:Receptors, Adrenergic / Q000378:metabolism*; D012106:Research / Q000639:trends; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism
D011941:Receptors, Adrenergic; D009638:Norepinephrine