p-Aminoacetophenonic acids produced by a mangrove endophyte: Streptomyces griseus subsp.
Three new p-aminoacetophenonic acids, named 7-(4-aminophenyl)-2,4-dimethyl-7-oxo-hept-5-enoic acid (1), 9-(4-aminophenyl)-7-hydroxy-2,4,6-trimethyl-9-oxo-non-2-enoic acid (2), and 12-(4-aminophenyl)-10-hydroxy-6-(1-hydroxyethyl)-7,9-dimethyl-12-oxo-dodeca-2,4-dienoic acid (3), were isolated from an endophyte of the mangrove plant Kandelia candel. The structures of 1-3 were elucidated using spectroscopic analyses, primarily NMR and MS.
Guan
Shu-Hong
SH
School of Pharmaceutical Sciences, Peking University, Beijing 100083, People's Republic of China.
Sattler
Isabel
I
Lin
Wen-Han
WH
Guo
De-An
DA
Grabley
Susanne
S
D000098:Acetophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002681:China; D005658:Fungi / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D006913:Hydroxysteroid Dehydrogenases / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D043982:Rhizophoraceae; D013237:Stereoisomerism; D013305:Streptomyces griseus / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000098:Acetophenones; D006913:Hydroxysteroid Dehydrogenases