Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass.
OBJECTIVE
We investigated the diagnostic value of a new system, the Innotrac Aio! immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays.


RESULTS
The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays.


CONCLUSIONS
There is strong evidence that the Innotrac Aio! system for cTnI measurement can be used reliably.
Weber
Michael
M
Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany. M.Weber@kerckhoff-klinik.de
Rau
Matthias
M
Madlener
Katharina
K
Elsaesser
Albrecht
A
Bankovic
Dragic
D
Mitrovic
Veselin
V
Hamm
Christian
C
D000208:Acute Disease; D015415:Biomarkers / Q000097:blood*; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000097:blood*; D052279:Creatine Kinase, MB Form / Q000032:analysis*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D009211:Myoglobin / Q000032:analysis*; D011933:Reagent Kits, Diagnostic; D020107:Troponin T / Q000032:analysis*
D015415:Biomarkers; D009211:Myoglobin; D011933:Reagent Kits, Diagnostic; D020107:Troponin T; D052279:Creatine Kinase, MB Form