Successful surgical correction of anal atresia in a transgenic cloned piglet.
Inbred strains of pig become indispensable for a wide range of biological studies. In biomedical science, it is generally accepted that somatic cell nuclear transfer (SCNT) technology with inbreed strain of pig is essential for xenotransplantation. In this study, we observed the anal atresia in a cloned pig which was derived from fetal fibroblast of inbreed miniature pig. A presumptive anal site of the cloned pig was excised and the rectum was sutured to apposed skin for treatment. This cloned piglet seemed to be normal with healthy status after surgery. This report can be useful for the treatment of anal atresia of cloned piglets.
Lee
Gab Sang
GS
Department of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Korea.
Kim
Hye Soo
HS
Lee
So Hyun
SH
Kim
Dae Yong
DY
Seo
Kang Moon
KM
Hyun
Sang Hwan
SH
Kang
Sung Keun
SK
Lee
Byeong Chun
BC
Hwang
Woo Suk
WS
D000818:Animals; D030801:Animals, Genetically Modified / Q000601:surgery*; D001006:Anus, Imperforate / Q000235:genetics / Q000601:surgery / Q000662:veterinary*; D019976:Cloning, Organism; D005260:Female; D020022:Genetic Predisposition to Disease; D013552:Swine / Q000002:abnormalities* / Q000235:genetics / Q000601:surgery*