title: [Surgical management of inflammatory granuloma which developed following subcutaneous injection of leuprorelin acetate: a case report].
abstract: A case of granuloma which developed following a subcutaneous injection of leuprorelin acetate is presented. A prominent induration developed at the site of injection with a three-month type preparation, and radical retropubic prostatectomy and simultaneous excision of the granulomas were requested by the patient since they were large, infectious and painful. Our experience may indicate the necessity of conversion from leuprorelin acetate to other drugs (e.g., goserelin acetate, castration) if a local induration, caused by a subcutaneous injection of leuprorelin acetate, has developed to a large granuloma.
authors.affiliation: The Department of Urology, Kitano Hospital, the Tazuke Kofukai Medical Research Institute.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Oida
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Shichiri
authors.forename: Noriyasu
authors.initials: N
authors.lastname: Takao
authors.forename: Toru
authors.initials: T
authors.lastname: Kanno
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kanamaru
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage* / Q000009:adverse effects*; D006099:Granuloma / Q000139:chemically induced* / Q000601:surgery*; D006801:Humans; D007249:Inflammation / Q000139:chemically induced; D007279:Injections, Subcutaneous; D016729:Leuprolide / Q000008:administration & dosage* / Q000009:adverse effects*; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy
chemical_list: D018931:Antineoplastic Agents, Hormonal; D016729:Leuprolide