Lymphoepithelioma-like carcinoma of the urinary bladder: a case report and discussion of differential diagnosis.
Lymphoepithelioma-like carcinoma (LELC) of the urinary bladder is very rare. It is mandatory to make differential diagnosis among lymphoma, chronic cystitis and LELC because of different therapeutic approach. A bladder tumor was found in a 90-year-old patient suffering from hematuria. After transurethral resection, undifferentiated tumor with prominent lymphoid infiltration was seen on light microscopy. Immunohistochemical examination demonstrated positive staining of tumor cells with cytokeratin (CK), epithelial membrane antigen and CK-20. We presented the case because of its rarity and related literature was reviewed.
Guresci
Servet
S
Department of Pathology, Trakya University Medical Faculty, 22030 Edirne, Turkey. gurescis@hotmail.com
Doganay
Latife
L
Altaner
Semsi
S
Atakan
H Irfan
HI
Kutlu
Kemal
K
D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D053554:Keratin-20; D007633:Keratins / Q000378:metabolism; D008297:Male; D018396:Mucin-1 / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery
C507499:KRT20 protein, human; D053554:Keratin-20; D018396:Mucin-1; D007633:Keratins