Recurrent pleomorphic adenoma of epipharynx following irradiation therapy.
We present a case of a 67-year-old female patient having a pleomorphic adenoma of epipharynx with intact fibrous capsula, which despite its benignity recurred and, moreover, responded quite well to irradiation therapy. The patient, at first, refused any therapy. Three years later, when the CT showed tumor enlargement she accepted only irradiation therapy, resulting in significant reduction of tumor size. Five years later the tumor recurred but without malignant transformation. She still refused surgery, but accepted re-irradiation therapy. After a three-year follow-up the patient has no symptoms of the tumor enlargement. This case shows that the irradiation therapy might be quite effective in the treatment of pleomorphic adenoma of epipharynx, but it is clear that much better results could be accomplished in combination with the surgery. In cases when the surgery is rejected or not possible because of the vicinity of the vital structures, we recommend the irradiation therapy as a therapy of the choice.
Zamolo
Gordana
G
Department of Pathology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia. gordanazamolo@yahoo.com
Coklo
Miran
M
Petković
Marija
M
Batinac
Tanja
T
Bosnar
Alan
A
Manestar
Darko
D
Dekanić
Andrea
A
Vojniković
Bozidar
B
D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000532:radiotherapy*; D000368:Aged; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D014057:Tomography, X-Ray Computed