Diagnosis of alpha+-thalassemias by determining the ratio of the two alpha-globin gene copies by oligonucleotide hybridization and melting curve analysis.
Timmann
Christian
C
Department of Molecular Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, and Institute of Medical Biometry and Statistics, University Hospital Schleswig-Holstein-Campus Lübeck, Lübeck, Germany. timmann@bni.uni-hamburg.de
Moenkemeyer
Florian
F
Evans
Jennifer A
JA
Foerster
Birgit
B
Tannich
Egbert
E
Haase
Sylvia
S
Sievertsen
Juergen
J
Kohne
Elisabeth
E
Horstmann
Rolf D
RD
D017931:DNA Primers; D018628:Gene Dosage; D005914:Globins / Q000235:genetics*; D006442:Glycated Hemoglobin / Q000235:genetics; D006801:Humans; D009693:Nucleic Acid Hybridization / Q000379:methods; D017085:alpha-Thalassemia / Q000175:diagnosis* / Q000235:genetics
D017931:DNA Primers; D005914:Globins; D006442:Glycated Hemoglobin