title: Dental procedures in adult patients with hereditary bleeding disorders: 10 years experience in three Italian Hemophilia Centers.
abstract: Excessive bleeding after dental procedures are one of the most frequent complications occurring in patients with hereditary bleeding disorders. In this retrospective study we collected data from 10 years of experience in the oral care of patients with congenital haemorrhagic disorders in three Italian Hemophilia Centers. Between 1993 and 2003, 247 patients with inherited bleeding disorders underwent 534 dental procedures including 133 periodontal treatments, 41 conservative dentistry procedures, 72 endodontic treatments and 288 oral surgery procedures. We recorded 10 bleeding complications (1.9%), most of which occurred in patients with severe/moderate haemophilia A undergoing multiple dental extractions. Thus, our protocol of management of patients with hereditary bleeding tendency undergoing oral treatment or surgery has been shown to be effective in preventing haemorrhagic complications.
authors.affiliation: Servizio di Immunoematologia e Trasfusione--Centro Emofilia, Azienda Ospedaliera di Verona, Verona, Italy. massimo.franchini@mail.azosp.vr.it
authors.forename: M
authors.initials: M
authors.lastname: Franchini
authors.forename: G
authors.initials: G
authors.lastname: Rossetti
authors.forename: A
authors.initials: A
authors.lastname: Tagliaferri
authors.forename: C
authors.initials: C
authors.lastname: Pattacini
authors.forename: D
authors.initials: D
authors.lastname: Pozzoli
authors.forename: C
authors.initials: C
authors.lastname: Lorenz
authors.forename: L
authors.initials: L
authors.lastname: Del Dot
authors.forename: G
authors.initials: G
authors.lastname: Ugolotti
authors.forename: C
authors.initials: C
authors.lastname: Dell'aringa
authors.forename: G
authors.initials: G
authors.lastname: Gandini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000150:complications* / Q000188:drug therapy; D001779:Blood Coagulation Factors / Q000627:therapeutic use; D003729:Dental Care / Q000379:methods*; D005260:Female; D006467:Hemophilia A / Q000150:complications / Q000188:drug therapy; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000209:etiology / Q000517:prevention & control; D019647:Oral Surgical Procedures / Q000009:adverse effects / Q000379:methods; D012189:Retrospective Studies; D014081:Tooth Extraction / Q000009:adverse effects / Q000379:methods; D014842:von Willebrand Diseases / Q000150:complications / Q000188:drug therapy
chemical_list: D000933:Antifibrinolytic Agents; D001779:Blood Coagulation Factors