title: Pathogenicity of Shigella in healthy carriers: a study in Vientiane, Lao People's Democratic Republic.
abstract: Shigella spp. isolated from diarrheal patients and non-diarrheal carriers were examined by PCR for the presence of two pathogenic genes, chromosomal ipaH and invasive plasmid encoded ial. Shigella spp. were detected in 7 of 72 diarrheal cases examined (9.7%), and 9 of 145 non-diarrheal cases (6.2%). All isolates from diarrheal cases harbored both ipaH and ial, while all isolates from non-diarrheal cases were positive for ipaH but not ial. These results suggested that Shigella spp. in healthy carriers were basically non-pathogenic.
authors.affiliation: Center for Laboratory and Epidemiology, Ministry of Health, Vientiane, Lao People's Democratic Republic.
authors.forename: Bounnanh
authors.initials: B
authors.lastname: Phantouamath
authors.forename: Noikaseumsy
authors.initials: N
authors.lastname: Sithivong
authors.forename: Sithat
authors.initials: S
authors.lastname: Insisiengmay
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ichinose
authors.forename: Naomi
authors.initials: N
authors.lastname: Higa
authors.forename: Tianyan
authors.initials: T
authors.lastname: Song
authors.forename: Masaaki
authors.initials: M
authors.lastname: Iwanaga
mesh_terms: D000293:Adolescent; D000328:Adult; D000942:Antigens, Bacterial / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002353:Carrier State / Q000382:microbiology* / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D004405:Dysentery, Bacillary / Q000382:microbiology* / Q000517:prevention & control; D005243:Feces / Q000382:microbiology; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007812:Laos; D008297:Male; D010957:Plasmids / Q000235:genetics; D012703:Serotyping; D012760:Shigella / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D014774:Virulence / Q000235:genetics
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C063500:ipaH protein, Shigella flexneri