title: Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.
abstract: Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
authors.affiliation: Department of Chemistry and Biochemistry, Mailcode 4409, Southern Illinois University, Carbondale, IL 62901-4409, USA.
authors.forename: Hari M R
authors.initials: HM
authors.lastname: Gardimalla
authors.forename: Deendayal
authors.initials: D
authors.lastname: Mandal
authors.forename: Philip D
authors.initials: PD
authors.lastname: Stevens
authors.forename: Max
authors.initials: M
authors.lastname: Yen
authors.forename: Yong
authors.initials: Y
authors.lastname: Gao
mesh_terms: D002175:Candida / Q000201:enzymology*; D002264:Carboxylic Acids / Q000737:chemistry*; D004800:Enzymes, Immobilized / Q000737:chemistry*; D005290:Ferric Compounds; D007700:Kinetics; D008049:Lipase / Q000737:chemistry*; D049329:Nanostructures; D011422:Propionates / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism
chemical_list: D002264:Carboxylic Acids; D004800:Enzymes, Immobilized; D005290:Ferric Compounds; D011422:Propionates; C000499:ferric oxide; D008049:Lipase; C035775:2-bromopropionic acid