title: Assessing, treating and managing patients with sepsis.
abstract: This article outlines the causes, signs and symptoms of systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock, the implications and available treatments. The article also highlights a campaign to reduce the incidence of sepsis and reflects on efforts to reduce healthcare-associated infections.
authors.affiliation: Accident and Emergency Department, Chesterfield Royal Hospital NHS Foundation Trust, Derbyshire. wayne.robson@chesterfieldroyal.nhs.uk
authors.forename: Wayne
authors.initials: W
authors.lastname: Robson
authors.forename: Julian
authors.initials: J
authors.lastname: Newell
mesh_terms: D002405:Catheterization, Central Venous; D015984:Causality; D003422:Critical Care / Q000379:methods; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods; D024802:Nurse's Role; D009730:Nursing Assessment; D011486:Protein C / Q000627:therapeutic use; D018805:Sepsis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D012772:Shock, Septic / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D011486:Protein C