title: GBV-C/HGV and HIV-1 coinfection.
abstract: An interesting interaction pattern has been found between HIV-1 and GBV-C/HGV, resulting in protection against progression to AIDS. The mechanisms involved in this interaction remain to be clarified. We examined the current knowledge concerning this coinfection and developed hypotheses to explain its effects. A better understanding of this interaction could result in new concepts, which may lead to new strategies to control HIV-1 replication and progression to AIDS.
authors.affiliation: Pró-Sangue Foundation, São Paulo, SP, Brazil.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Maidana
authors.forename: Ester Cerdeira
authors.initials: EC
authors.lastname: Sabino
authors.forename: Esper Georges
authors.initials: EG
authors.lastname: Kallas
mesh_terms: D018450:Disease Progression; D018178:Flaviviridae Infections / Q000150:complications* / Q000276:immunology; D029407:GB virus C / Q000276:immunology*; D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000276:immunology; D006801:Humans