title: [A synthesis of tritium-labeled olanzapine].
abstract: A synthesis of olanzapine, 2-methyl-10-(4-methyl-1-piperazinyl)-4H-thieno[2,3-b][1,5]benzodiazepine was carried out, and the conditions for its tritium labeling were optimized, to get a tritium-labeled olanzapine preparation with molar radioactivity of 12 Ci/mmol.
authors.forename: V P
authors.initials: VP
authors.lastname: Shevchenko
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Nagaev
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Kuznetsov
authors.forename: E V
authors.initials: EV
authors.lastname: Polunin
authors.forename: A A
authors.initials: AA
authors.lastname: Zozulia
authors.forename: N F
authors.initials: NF
authors.lastname: Miasoedov
mesh_terms: D001569:Benzodiazepines / Q000138:chemical synthesis / Q000737:chemistry; D007553:Isotope Labeling; D015394:Molecular Structure; D000077152:Olanzapine; D014316:Tritium / Q000737:chemistry*
chemical_list: D014316:Tritium; D001569:Benzodiazepines; D000077152:Olanzapine