title: Reversal of laser in situ keratomileusis-induced ectasia with intraocular pressure reduction.
abstract: A 40 year-old woman had laser in situ keratomileusis for --7.75 --0.75 x 20 in the right eye. Preoperative examinations, including topography, pachymetry, and intraocular pressures (IOPs), were normal, and best spectacle-corrected visual acuity (BSCVA) was 20/20 in each eye. By 4 months postoperatively, the uncorrected visual acuity and BSCVA in the right eye had decreased to 20/40. Corneal topography of that eye was consistent with ectasia. One drop per day of timolol 0.5% (Timoptic XE) was prescribed. Five months postoperatively, the IOP had decreased and BSCVA and topography had improved. At 11 months, BSCVA returned to 20/20 and corneal topography normalized. Topographic difference maps were used to monitor corneal shape changes. In this case, early reduction in IOP completely reversed the ectasia.
authors.affiliation: Boxer Wachler Vision Institute, Beverly Hills, California 90210, USA.
authors.forename: James Andrew
authors.initials: JA
authors.lastname: Hiatt
authors.forename: Brian S Boxer
authors.initials: BS
authors.lastname: Wachler
authors.forename: Colin
authors.initials: C
authors.lastname: Grant
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D003316:Corneal Diseases / Q000209:etiology / Q000503:physiopathology*; D019781:Corneal Topography; D004108:Dilatation, Pathologic / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D009216:Myopia / Q000601:surgery; D013999:Timolol / Q000008:administration & dosage*; D014792:Visual Acuity
chemical_list: D000959:Antihypertensive Agents; D013999:Timolol