Titanium(IV)-catalyzed enantioselective sulfenylation of beta-ketoesters.
A [Ti(TADDOLato)] complex (1) catalyzes the enantioselective sulfenylation of beta-ketoesters using phenylsulfenyl chloride, giving ees of up to 88% and yields of up to 95%. The reaction does not require the presence of a base. [reaction: see text]
Jereb
Marjan
M
Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
Togni
Antonio
A