title: Lymphoepithelioma-like carcinoma of the urinary bladder: a case report and discussion of differential diagnosis.
abstract: Lymphoepithelioma-like carcinoma (LELC) of the urinary bladder is very rare. It is mandatory to make differential diagnosis among lymphoma, chronic cystitis and LELC because of different therapeutic approach. A bladder tumor was found in a 90-year-old patient suffering from hematuria. After transurethral resection, undifferentiated tumor with prominent lymphoid infiltration was seen on light microscopy. Immunohistochemical examination demonstrated positive staining of tumor cells with cytokeratin (CK), epithelial membrane antigen and CK-20. We presented the case because of its rarity and related literature was reviewed.
authors.affiliation: Department of Pathology, Trakya University Medical Faculty, 22030 Edirne, Turkey. gurescis@hotmail.com
authors.forename: Servet
authors.initials: S
authors.lastname: Guresci
authors.forename: Latife
authors.initials: L
authors.lastname: Doganay
authors.forename: Semsi
authors.initials: S
authors.lastname: Altaner
authors.forename: H Irfan
authors.initials: HI
authors.lastname: Atakan
authors.forename: Kemal
authors.initials: K
authors.lastname: Kutlu
mesh_terms: D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D053554:Keratin-20; D007633:Keratins / Q000378:metabolism; D008297:Male; D018396:Mucin-1 / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology* / Q000601:surgery
chemical_list: C507499:KRT20 protein, human; D053554:Keratin-20; D018396:Mucin-1; D007633:Keratins