Sodium chloride enhanced oligomerization of L-arginine.
NaCl significantly enhanced the longer oligoarginine formation in the oligomerization of L-arginine activated by N,N'-carbonyldiimidazole (CDI) in homogeneous aqueous solution. The optimal concentration of NaCl for the highest yield of longer oligoarginine formation is around 1M. It is suggested that the weak interactions of Cl(-) with the positive-charged guanidinium group of the oligoarginines formed in the oligomerization of L-arginine are responsible for the enhancement by NaCl.
Xin
Liang
L
Institute of Biophysics, Chinese Academy of Sciences, Beijing.
Ma
Yan-Lin
YL
Liu
Yi-Nan
YN
Yan
Qin
Q
Wang
Kong-Jiang
KJ
D001120:Arginine / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry; D009842:Oligopeptides / Q000138:chemical synthesis*; D012965:Sodium Chloride / Q000737:chemistry* / Q000494:pharmacology; D012996:Solutions; D014867:Water / Q000737:chemistry
D007093:Imidazoles; D009842:Oligopeptides; D012996:Solutions; D014867:Water; D012965:Sodium Chloride; D001120:Arginine