Propionibacterium infection associated with bovine pericardium dural allograft. Case report.
Propionibacteria are known to play a part in postneurosurgical infections, primarily those involving ventricular shunts. Nevertheless, little is known about the association between dural allografts and propionibacterium infections. Two patients underwent craniotomy for supratentorial meningiomas and each received a dural allograft. Both patients subsequently presented with delayed epidural fluid collections several weeks after surgery. Propionibacterium species was cultured in samples from both patients. The allografts were removed and the patients were treated with appropriate antibiotic agents; one patient underwent an interval craniectomy. Both patients demonstrated neuroimaging and clinical improvement after surgery and antiobiotic therapy. These cases demonstrate the association of propionibacterium infections with dural allografts. Furthermore, in patients with latent and indolent infections, Propionibacterium spp. should be suspected and treated appropriately.
Barkhoudarian
Garni
G
Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan 48109-0338, USA.
Hoff
Julian T
JT
Thompson
B Gregory
BG
D000368:Aged; D001684:Biological Dressings / Q000009:adverse effects*; D004388:Dura Mater / Q000601:surgery*; D013354:Empyema, Subdural / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011424:Propionibacterium