title: Particle migration and gap healing around trabecular metal implants.
abstract: Bone on-growth and peri-implant migration of polyethylene particles were studied in an experimental setting using trabecular metal and solid metal implants. Cylindrical implants of trabecular tantalum metal and solid titanium alloy implants with a glass bead blasted surface were inserted either in an exact surgical fit or with a peri-implant gap into a canine knee joint. We used a randomised paired design. Polyethylene particles were injected into the knee joint. In both types of surgical fit we found that the trabecular metal implants had superior bone ongrowth in comparison with solid metal implants (exact fit: 23% vs. 7% [p=0.02], peri-implant gap: 13% vs. 0% [p=0.02]. The number of peri-implant polyethylene particles was significantly reduced around the trabecular metal implants with a peri-implant gap compared with solid implants.
authors.affiliation: Orthopedic Research Laboratory, Aarhus University Hospital, Nørrebrogade 44, Building 1A, 8000, Aarhus, Denmark. ole_rahbek@mail.dk
authors.forename: O
authors.initials: O
authors.lastname: Rahbek
authors.forename: S
authors.initials: S
authors.lastname: Kold
authors.forename: B
authors.initials: B
authors.lastname: Zippor
authors.forename: S
authors.initials: S
authors.lastname: Overgaard
authors.forename: K
authors.initials: K
authors.lastname: Søballe
mesh_terms: D000535:Aluminum; D000818:Animals; D020099:Coated Materials, Biocompatible; D004285:Dogs; D005548:Foreign-Body Migration; D007720:Knee Prosthesis / Q000009:adverse effects*; D010316:Particle Size; D020959:Polyethylene / Q000009:adverse effects*; D011475:Prosthesis Failure; D011897:Random Allocation; D018709:Statistics, Nonparametric; D013499:Surface Properties; D013635:Tantalum; D014025:Titanium; D014945:Wound Healing / Q000502:physiology*
chemical_list: D020099:Coated Materials, Biocompatible; D013635:Tantalum; D020959:Polyethylene; D000535:Aluminum; D014025:Titanium