Phase-referenced Doppler optical coherence tomography in scattering media.
We present a fiber-based, low-coherence interferometer that significantly reduces phase noise by incorporating a second, narrowband, continuous-wave light source as a phase reference. By incorporating this interferometer into a Doppler OCT system, we demonstrate significant velocity noise reduction in reflective and scattering samples using processing techniques amenable to real-time implementation. We also demonstrate 90% suppression of velocity noise in a flow phantom.
Pedersen
Cameron J
CJ
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207, USA.
Yazdanfar
Siavash
S
Westphal
Volker
V
Rollins
Andrew M
AM
D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation* / Q000379:methods; D007089:Image Enhancement / Q000295:instrumentation* / Q000379:methods; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation* / Q000379:methods; D008027:Light; D008857:Microscopy, Interference / Q000295:instrumentation* / Q000379:methods; D009391:Nephelometry and Turbidimetry / Q000295:instrumentation* / Q000379:methods; D019047:Phantoms, Imaging; D012542:Scattering, Radiation; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods