title: Surgical treatment for lung cancer in octogenarians.
abstract: OBJECTIVE
  We conducted this study in order to determine how we should perform the surgical treatment for clinical stage I non-small cell lung cancer (NSCLC) in octogenarians.
  
  
  METHODS
  Thirty-three octogenarians with clinical stage I NSCLC participated in this study. They were retrospectively divided into two groups: one group of 11 patients who underwent a lymph node dissection (ND group), and one group of 22 patients who did not undergo this procedure (ND0 group). We analyzed the surgical invasiveness, morbidity, mortality, and survival in both groups.
  
  
  RESULTS
  The morbidity rate in the ND group (45%) was higher than that in the ND0 group (23%); however, the difference was no statistically significant (P = 0.1805). There was no significant difference in the overall survival rates of the two groups (P = 0.1647), and the median survival time of the ND0 group (76 months) was slightly longer than that of the ND group (26 months). There was no significant difference in local recurrence rate between the two groups (9.1% vs 4.5%, P = 0.6059).
  
  
  CONCLUSIONS
  We thus conclude that a limited operation without lymph node dissection might be the best surgical treatment for carefully selected octogenarians with clinical stage I NSCLC.
authors.affiliation: Division of Surgical Oncology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Muraoka
authors.forename: Tadayuki
authors.initials: T
authors.lastname: Oka
authors.forename: Shinji
authors.initials: S
authors.lastname: Akamine
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Tagawa
authors.forename: Nobufumi
authors.initials: N
authors.lastname: Sasaki
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ikuta
authors.forename: Masao
authors.initials: M
authors.lastname: Inoue
authors.forename: Takatomo
authors.initials: T
authors.lastname: Yamayoshi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hashizume
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tagawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagayasu
mesh_terms: D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000601:surgery*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome