title: Complications of sedation and critical illness.
abstract: Critically ill patients require sedation to reduce anxiety, agitation, and achieve therapeutic goals. Over-sedation in combination with multiple causes for extreme muscle weakness, however, interferes with recovery from critical illness. This article describes contributing factors and explores methods of preventing over-sedation and related sequelae.
authors.affiliation: College of Nursing, Texas Woman's University, Houston, TX 77030, USA. jfoster@twu.edu
authors.forename: Jan
authors.initials: J
authors.lastname: Foster
mesh_terms: D000328:Adult; D001510:Bed Rest / Q000009:adverse effects; D016292:Procedural Sedation / Q000009:adverse effects* / Q000191:economics / Q000379:methods / Q000451:nursing; D003243:Consciousness / Q000187:drug effects; D017281:Cost of Illness; D003422:Critical Care / Q000191:economics / Q000379:methods*; D016638:Critical Illness / Q000191:economics / Q000628:therapy; D016903:Drug Monitoring / Q000379:methods / Q000451:nursing; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009133:Muscular Atrophy / Q000209:etiology / Q000517:prevention & control; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects; D009730:Nursing Assessment / Q000379:methods; D011595:Psychomotor Agitation / Q000209:etiology / Q000517:prevention & control; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000628:therapy; D012307:Risk Factors
chemical_list: D009466:Neuromuscular Blocking Agents