17-beta-estradiol eluting stent versus phosphorylcholine-coated stent for the treatment of native coronary artery disease.
In this study we randomly compared the estradiol eluting stent (17-beta-E) with phosphorylcholine (PC)-coated stents in native coronary arteries. The incidence of angiographic restenosis was 23% in the 17-beta-E group and 31% in the PC group (p = 0.34). The major adverse cardiovascular event rates were also similar in the 2 groups (17% in the 17-beta-E group vs 22% in the PC group, p = 0.47). The mid-term clinical and angiographic outcomes did not indicate superiority of the 17-beta-E eluting stent over the control PC stent.
Airoldi
Flavio
F
Interventional Cardiology Unit, San Raffaele Hospital, Milan, Italy.
Di Mario
Carlo
C
Ribichini
Flavio
F
Presbitero
Patrizia
P
Sganzerla
Paolo
P
Ferrero
Valeria
V
Vassanelli
Corrado
C
Briguori
Carlo
C
Carlino
Mauro
M
Montorfano
Matteo
M
Biondi-Zoccai
Giuseppe G L
GG
Chieffo
Alaide
A
Ferrari
Angela
A
Colombo
Antonio
A
D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control; D004958:Estradiol / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010767:Phosphorylcholine / Q000627:therapeutic use*; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
D020099:Coated Materials, Biocompatible; D010767:Phosphorylcholine; D004958:Estradiol