GBV-C/HGV and HIV-1 coinfection.
An interesting interaction pattern has been found between HIV-1 and GBV-C/HGV, resulting in protection against progression to AIDS. The mechanisms involved in this interaction remain to be clarified. We examined the current knowledge concerning this coinfection and developed hypotheses to explain its effects. A better understanding of this interaction could result in new concepts, which may lead to new strategies to control HIV-1 replication and progression to AIDS.
Maidana
Maria Teresa
MT
Pró-Sangue Foundation, São Paulo, SP, Brazil.
Sabino
Ester Cerdeira
EC
Kallas
Esper Georges
EG
D018450:Disease Progression; D018178:Flaviviridae Infections / Q000150:complications* / Q000276:immunology; D029407:GB virus C / Q000276:immunology*; D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000276:immunology; D006801:Humans