title: Feline acromegaly: a review of the syndrome.
abstract: Acromegaly is characterized by chronic excessive growth hormone (GH) secretion by the pituitary gland. Feline acromegaly is most commonly caused by a functional pituitary tumor. Definitive diagnosis can be difficult because of the gradual disease onset, subtle clinical signs, unavailability of relevant laboratory tests, and client financial investment. The most significant clinical finding of acromegaly is the presence of insulin-resistant diabetes mellitus. Diagnosis is currently based upon brain imaging and measurement of serum GH and/or insulin-like growth factor-1 concentrations. Definitive treatment in cats is not well described, but radiation therapy appears promising.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA.
authors.forename: Charles A
authors.initials: CA
authors.lastname: Hurty
authors.forename: Bente
authors.initials: B
authors.lastname: Flatland
mesh_terms: D000172:Acromegaly / Q000097:blood / Q000175:diagnosis / Q000532:radiotherapy / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000097:blood / Q000175:diagnosis* / Q000532:radiotherapy; D002415:Cats; D003920:Diabetes Mellitus / Q000209:etiology / Q000662:veterinary; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D007333:Insulin Resistance; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D011379:Prognosis
chemical_list: D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone