title: Synthesis of novel polyethers in a geometrically precise conformation.
abstract: [reaction: see text] A convergent design for the preparation of a polyoxyethylene-based channel molecule is presented, and the synthesis of the key unit 2 required for the projected construction is described. The essential elements of the design included face to face oriented macrorings spaced by rigid trans-fused oxanes. The strategy combines conformational predictability of C-linked oxanyl systems and ring-closing metathesis for the synthesis of crown ethers with engineerable ion-binding abilities.
authors.affiliation: Instituto de Investigaciones Químicas, CSIC, Américo Vespucio, s/n, Isla de la Cartuja, 41092 Seville, Spain.
authors.forename: R M
authors.initials: RM
authors.lastname: Rodríguez
authors.forename: E Q
authors.initials: EQ
authors.lastname: Morales
authors.forename: M
authors.initials: M
authors.lastname: Delgado
authors.forename: C G
authors.initials: CG
authors.lastname: Espínola
authors.forename: E
authors.initials: E
authors.lastname: Alvarez
authors.forename: R
authors.initials: R
authors.lastname: Pérez
authors.forename: J D
authors.initials: JD
authors.lastname: Martín