The effect of xin mai tong capsules in protecting survival cardiac muscles of the patients with acute myocardial infarction.
To study the effect of Composite Xin Mai Tong capsules in protecting survival cardiac muscles in patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary angioplasty (PTCA) operation. The treatment with Composite XMT capsules started 3 days prior to the operation and continued for a period of 4 weeks; and its effect on the number of segments of nuclide resting ventricular myocardial imaging, the nuclide defect extension score (ES) and nuclide defect severity score (SS), and the level of vascular endothelial growth factor (VEGF) of circulatory blood were determined and compared with that of the control group. More segments originally scored 1 turning to be scored 2 in nuclide imaging were seen in the treatment group than in the control group; and smaller ES and less SS seen in the former than in the latter group (P < 0.05). Composite XMT capsules play an active role in myocardial salvage by promoting its metabolism and expression of circulatory VEGF. Its angiogenesis-like action helps establish collateral flow and has a positive role in myocardial salvage.
Ruixiang
Qiu
Q
TCM Department of the First Affiliated Hospital, Sun Yatsen University of Medical Sciences, Guangzhou 510080, China.
Jun
Feng
F
Jun
Meng
M
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002214:Capsules; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000628:therapy*; D008517:Phytotherapy; D042461:Vascular Endothelial Growth Factor A / Q000097:blood
D002214:Capsules; D004365:Drugs, Chinese Herbal; D042461:Vascular Endothelial Growth Factor A