title: Sodium chloride enhanced oligomerization of L-arginine.
abstract: NaCl significantly enhanced the longer oligoarginine formation in the oligomerization of L-arginine activated by N,N'-carbonyldiimidazole (CDI) in homogeneous aqueous solution. The optimal concentration of NaCl for the highest yield of longer oligoarginine formation is around 1M. It is suggested that the weak interactions of Cl(-) with the positive-charged guanidinium group of the oligoarginines formed in the oligomerization of L-arginine are responsible for the enhancement by NaCl.
authors.affiliation: Institute of Biophysics, Chinese Academy of Sciences, Beijing.
authors.forename: Liang
authors.initials: L
authors.lastname: Xin
authors.forename: Yan-Lin
authors.initials: YL
authors.lastname: Ma
authors.forename: Yi-Nan
authors.initials: YN
authors.lastname: Liu
authors.forename: Qin
authors.initials: Q
authors.lastname: Yan
authors.forename: Kong-Jiang
authors.initials: KJ
authors.lastname: Wang
mesh_terms: D001120:Arginine / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry; D009842:Oligopeptides / Q000138:chemical synthesis*; D012965:Sodium Chloride / Q000737:chemistry* / Q000494:pharmacology; D012996:Solutions; D014867:Water / Q000737:chemistry
chemical_list: D007093:Imidazoles; D009842:Oligopeptides; D012996:Solutions; D014867:Water; D012965:Sodium Chloride; D001120:Arginine