[Analysis of correlative factors affecting IIEF-5 scores of type 2 diabetic patients].
OBJECTIVE
To investigate the correlative factors affecting the IIEF-5 scores of the patient with type 2 diabetic mellitus (T2DM).


METHODS
A total of 149 T2DM patients were investigated for the relationships between their IIEF-5 score and such factors as age, body mass index (BMI), fasting plasma glucose (FPG), 2hPG, insulin (INS), GHbA1c, C-peptide, nitric oxide (NO), testosterone (T), estradiol (E2), the ratio of testosterone to estradiol (T/E), erythrocyte aldose reductase (AR), drinking, smoking, concomitant diseases, complications and medication.


RESULTS
The scores of the groups of smoking, complication, medication and concomitant disease were significantly lower than those of the controls. There was significant negative correlation between IIEF-5 scores and age, BMI, FPG, 2hPG, INS, GHbA1c and AR (P < 0.05), and significant positive correlation between IIEF-5 scores and NO (P < 0.05). But there was no correlation between drinking, T, E2 and T/E2 (P > 0.05).


CONCLUSIONS
Many factors may affect the IIEF-5 scores of T2DM patients.
Guo
Tie-Cheng
TC
Department of Endocrinology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. guotctj@163.com
Zhang
Mu-Xun
MX
Zhang
Jian-Hua
JH
Xiao
Feng
F
Feng
Lin
L
D000328:Adult; D000367:Age Factors; D000368:Aged; D000449:Aldehyde Reductase / Q000097:blood; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000453:epidemiology; D005163:Factor Analysis, Statistical; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood; D010410:Penile Erection / Q000502:physiology*; D012044:Regression Analysis; D011795:Surveys and Questionnaires
D009569:Nitric Oxide; D000449:Aldehyde Reductase