title: Octogenarians undergoing cardiac surgery outlive their peers: a case for early referral.
abstract: OBJECTIVE
  To examine short and long term outcomes of octogenarians having heart operations and to analyse the interaction between patient and treatment factors.
  
  
  METHODS
  Multivariate analysis of prospectively collected data and a survival comparison with an age and sex matched national population. The outcomes were base in-hospital mortality, risk stratified by logistic EuroSCORE (European system for cardiac operative risk evaluation), and long term survival.
  
  
  RESULTS
  12,461 consecutive patients (706 over 80 years) operated on between 1996 and 2003 in a regional UK unit were studied. Octogenarians more often had impaired ventricular function, pulmonary hypertension, and valve operations. They also included a higher proportion of women, had a higher serum creatinine concentration, and had a trend towards more unstable angina. Younger patients had a higher prevalence of previous cardiac operation, previous myocardial infarction, and diabetes. The in-hospital mortality rate was 3.9% for all patients (EuroSCORE predicted 6.1%, p < 0.001) and 9.8% for octogenarians (predicted 14.1%, p = 0.002). Long bypass time and non-elective surgery increased the risk of death above EuroSCORE prediction in both groups. A greater proportion of octogenarians stayed in intensive care more than 24 hours (37% v 23%, p < 0.001). Long term survival was significantly better in the study patients than in a general population with the same age-sex distribution (survival rate at five years 82.1% v 55.9%, p < 0.001).
  
  
  CONCLUSIONS
  Cardiac surgery in a UK population of octogenarians produced excellent results. Elective referrals should be encouraged in all age groups.
authors.affiliation: Papworth Hospital, Cambridge CB3 8RE, UK.
authors.forename: S C
authors.initials: SC
authors.lastname: Stoica
authors.forename: F
authors.initials: F
authors.lastname: Cafferty
authors.forename: J
authors.initials: J
authors.lastname: Kitcat
authors.forename: R J F
authors.initials: RJ
authors.lastname: Baskett
authors.forename: M
authors.initials: M
authors.lastname: Goddard
authors.forename: L D
authors.initials: LD
authors.lastname: Sharples
authors.forename: F C
authors.initials: FC
authors.lastname: Wells
authors.forename: S A M
authors.initials: SA
authors.lastname: Nashef
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D004812:Epidemiologic Methods; D005260:Female; D006299:Health Services for the Aged; D006331:Heart Diseases / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012017:Referral and Consultation / Q000706:statistics & numerical data; D016896:Treatment Outcome