title: [The role of monitoring of hemodynamic parameters in intensive infusion therapy].
abstract: Pathophysiological mechanisms of intensive infusion therapy (IT) should be understood to provide effective practical use of this method for treating patients in critical states. Adequate IT should take into account the decrease in the efficiency of compensation mechanism and absence of reserve capacity of basic functional systems of human body. This allows the results of treatment of heavy patients to be improved, The goal of this work was to demonstrate that IT can be used not only as a therapeutic procedure but also as a diagnostic test intended to determine specific individual features of the compensatory adaptive reactions of the cardiovascular system (CVS) of patient. The tactics of IT can be adapted and optimized using the results of the CVS reaction to the liquid volume load test. The role of monitoring of hemodynamic parameters in IT was analyzed. Evaluation of patent reserves allows the following parameters of infusion to be varied: flow rate, volume, temperature, pH, and osmolarity of infusion solutions; succession and time of their infusion. Circadian rhythms of human CVS should also be taken into account. The following hemodynamic parameters should be monitored during IT: cardiac output, general peripheral resistance of blood vessels, and aqueous sectors. This monitoring can be used in mathematical simulation of changes in the parameters of central hemodynamics and determination of prognostic criteria.
mesh_terms: D003422:Critical Care; D006439:Hemodynamics; D006801:Humans; D007263:Infusions, Parenteral; D008991:Monitoring, Physiologic / Q000379:methods*; D013318:Stroke Volume