Transmission of viruses through corneal transplantation.
Transmission of viruses through transplantation has become a major concern for surgeons and tissue banks. Keratoplasty has been the first transplantation procedure in which transmission of a virus from the donor to the recipient has been proven, and recently, herpes has been suggested as a transmittable disease via corneal transplantation. In this article we review the history of viral transmission through transplantation, especially focusing on keratoplasty, and develop the recent updates on transmission of HSV through corneal grafting, its implications for surgeons and eye banks, and further insights into viral security in eye banks.
Robert
Pierre-Yves R
PY
Department of Ophthalmology, CHU Dupuytren, Limoges, France. pierre-yves.robert@unilim.fr
Adenis
Jean-Paul
JP
Denis
François
F
Ranger-Rogez
Sylvie
S
D016039:Corneal Transplantation / Q000009:adverse effects*; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D005125:Eye Banks / Q000379:methods / Q000592:standards; D006561:Herpes Simplex / Q000635:transmission; D006801:Humans; D014777:Virus Diseases / Q000635:transmission*