[Morphologic and physiochemical properties of bovine jugular conduit stabilized by dye-mediated poto-oxidation].
OBJECTIVE
To determine the morphologic and physiochemical properties of bovine jugular conduit with valves stabilized by dye-mediated photo-oxidation.


METHODS
Twenty-four bovine jugular conduits with valves were divided into 3 groups and treated with dye-mediated photo-oxidation (Group I), glutaraldehyde (Group II) and untreated group (Group II), respectively. Morphologic and physiochemical properties of the 3 groups, including wall thickness, diameter, tissue water content, heat shrinking temperature, breaching strength, and tissue protein extraction assay were studied.


RESULTS
There was no difference in wall thickness, diameter, tissue water content, and heat shrinking temperature between Group I and II ,but there was significant difference between Group I and II. The breaching strength of Group I was higher than that of Group IU (P < 0.05), but lower than that of Group II (P < 0. 05). A decrease in extractable tissue protein was found in Group I and II.


CONCLUSIONS
The dye-mediated photooxidation can effectively preserve the structure and the anti-regurgitation function of valves and improve the tissue stability and enhance the tension of bovine jugular conduit with valves.
Feng
Yao-Guang
YG
Department of Cardiothoracic Surgery, Second Xiangya Hospital, Central South University, Changsha, China.
Wu
Zhong-Shi
ZS
Hu
Jiang-Guo
JG
Hu
Tie-Hui
TH
Zhang
Jing-Chao
JC
Xu
Zhao-Jun
ZJ
Wang
Hui
H
Ma
Zhong-Xia
ZX
D000818:Animals; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D002417:Cattle; D007601:Jugular Veins / Q000033:anatomy & histology / Q000502:physiology; D008027:Light; D008422:Materials Testing; D008751:Methylene Blue / Q000494:pharmacology*; D010083:Oxidants, Photochemical / Q000494:pharmacology*; D010084:Oxidation-Reduction
D010083:Oxidants, Photochemical; D008751:Methylene Blue