[Vertebral trabecular network analysis on CT images].
OBJECTIVE
Comparing texture analysis, density measurement and visual quantification of trabecular network on spine CT images, to better evaluate bone architecture in osteoporosis.


METHODS
Seventeen patients, aged 19 to 84 years, were included. One patient presented osteoporotic fractures. High resolution computed tomographic (HR-CT) images of the third lumbar vertebra were acquired using a Somatom 4 plus CT (Siemens) in a strict axial orientation with FOV of 12 cm and slice thickness of 1 mm. The size of the Region Of Interest was 1,6 cm(2). Three analyses were performed on this ROI: Density (in Hounsfield Unity), texture analysis (run length) and features inspired from bone histomorphometry (Bone Volume/Tissue Volume).


RESULTS
Density measurement, run length methods and BV/TV provided consistent results with regards to age. Indeed density, run length and BV/TV results were lower for older patients with more advanced bone trabeculra alterations.


CONCLUSIONS
Only BV/TV and run length parameters seemed to show additional information on trabecular network architecture. The contribution of these two measurements to diagnose and classify osteoporosis will be the goal of a clinical study.
Lasbleiz
J
J
Département de Radiologie et d'Imagerie Médicale, Hôpital Sud CHU Rennes. jeremy.lasbleiz@chu-rennes.fr
Burgun
A
A
Marin
F
F
Rolland
Y
Y
Duvauferrier
R
R
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging; D012737:Sex Factors; D016103:Spinal Fractures / Q000000981:diagnostic imaging; D013131:Spine / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*