Analysis of microarray experiments for pulmonary fibrosis.
Microarray technology allows the investigator to examine the simultaneous expression of thousands of genes in a given cell or tissue. Such experiments that probe tens of thousands of genes produce immense amounts of information. In recent years, there has been a steady increase in the availability of tools for analysis of microarray data. Although many commercial tools are being aggressively marketed, we mostly use shareware tools. In this chapter, we present our approach to the analysis of microarray data mainly using tools that were generated by our collaborators or that are freely available. Step-by-step explanations of software operation are provided.
Davé
Nilesh B
NB
Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Kaminski
Naftali
N
D000465:Algorithms; D000818:Animals; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods; D005786:Gene Expression Regulation; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D011658:Pulmonary Fibrosis / Q000235:genetics*; D012984:Software; D013223:Statistics as Topic