title: Inadvertent intrathecal injection of labetalol in a patient undergoing post-partum tubal ligation.
abstract: After receiving a continuous spinal anesthetic for labor following an inadvertent dural puncture with a 17-gauge epidural needle, a morbidly obese parturient underwent post-partum tubal ligation 12 h after vaginal delivery. The patient received a total of 2 mL of 0.75% hyperbaric bupivacaine for the surgery. In response to moderate hypertension the patient received intravenous labetalol hydrochloride 20 mg. She subsequently was inadvertently administered approximately 15 mg of labetalol through the spinal catheter. The spinal catheter was removed immediately after the procedure. She suffered no apparent adverse neurologic effects.
authors.affiliation: Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA 22908-0710, USA. pjb8y@virginia.edu
authors.forename: P J
authors.initials: PJ
authors.lastname: Balestrieri
authors.forename: M S
authors.initials: MS
authors.lastname: Hamza
authors.forename: P H
authors.initials: PH
authors.lastname: Ting
authors.forename: R S
authors.initials: RS
authors.lastname: Blank
authors.forename: C T
authors.initials: CT
authors.lastname: Grubb
mesh_terms: D000328:Adult; D016362:Analgesia, Obstetrical; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D002045:Bupivacaine; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007278:Injections, Spinal; D007741:Labetalol / Q000008:administration & dosage*; D019300:Medical Errors; D009767:Obesity, Morbid; D011247:Pregnancy; D011248:Pregnancy Complications; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy; D013246:Sterilization, Tubal
chemical_list: D000779:Anesthetics, Local; D000959:Antihypertensive Agents; D007741:Labetalol; D002045:Bupivacaine