Toxic keratopathy-related corneal dehydration after laser in situ keratomileusis.
A 33-year-old woman had progressive blurred vision 2 weeks after uneventful laser in situ keratomileusis surgery. Initial satisfactory uncorrected visual acuity (UCVA) was complicated by postoperative dry eye and drug toxicity. Slitlamp biomicroscopy revealed diffuse punctate epithelial keratitis and inferior corneal epithelial defect with rolled-up epithelium on the flaps and the inferior unoperated cornea in both eyes. Diffuse inflammatory cell infiltrates were evident in the stroma. Stromal thinning was evident on serial Orbscan (Bausch & Lomb) and pachymetry examinations, and a hyperopic shift of almost +6 diopters was observed in the refractive error in both eyes. These examinations showed a gradual recovery of stromal thickness after copious hydration with balanced salt solution. The UCVA was 1.0 in both eyes after corneal rehydration.
Lim
Gerald Chee-Sheong
GC
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Lin
Hsin-Chiung
HC
Shen
Su-Chin
SC
Lin
Ken-Kuo
KK
D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects*; D019781:Corneal Topography; D003881:Dermatomycoses / Q000188:drug therapy; D015352:Dry Eye Syndromes / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D019573:Epithelium, Corneal / Q000187:drug effects*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D020731:Keratomileusis, Laser In Situ; D008508:Medication Errors / Q000009:adverse effects*; D011183:Postoperative Complications; D015532:Rehydration Solutions / Q000008:administration & dosage; D014792:Visual Acuity
D000935:Antifungal Agents; D015532:Rehydration Solutions