Bacterial meningitis in children: a French prospective study.
From January 2001 through December 2003, a total of 1084 children with bacterial meningitis were enrolled in a prospective French nationwide survey. The most frequent pathogens found in children older than 28 days were Neisseria meningitis (55.3%) and Streptococcus pneumoniae (33.4%). S. pneumoniae was the most frequent pathogen found among infants aged 2-12 months (49.5%), whereas N. meningitidis was the most frequent pathogen among children >12 months old (69.7%). Approximately one-half of S. pneumoniae isolates had diminished susceptibility to penicillin. The case-fatality rates were 7.6% for children with N. meningitidis meningitis and 10.8% for children with S. pneumoniae infection.
Bingen
Edouard
E
Service de Microbiologie EA3105, Hôpital Robert Debré, Paris, France. edouard.bingen@rdb.ap-hop-paris.fr
Levy
Corinne
C
de la Rocque
France
F
Boucherat
Michel
M
Varon
Emmanuelle
E
Alonso
Jean Michel
JM
Dabernat
Henri
H
Reinert
Philippe
P
Aujard
Yannick
Y
Cohen
Robert
R
D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D016920:Meningitis, Bacterial / Q000453:epidemiology* / Q000382:microbiology