[The research progress in the disease model of knock-out mouse].
The knock-out technology is an effective means in studying the gene function of organism. The disease model of gene knock-out mouse is of significance in understanding the gene function and pathogenesis of human disease. The available models of gene knock-out mouse are classified and summarized to promote the development of related research.
Yin
Hai-fang
HF
National Laboratory of Agrobiotechnology, China Agricultural University, Beijing100094, China.
Wang
Qiu-ju
QJ
Li
Ning
N