Future contributions on genetics.
It has become obvious from epidemiological studies in families of patients affected or from twin studies, that most psychiatric disorders are in part genetically determined. Genetics have raised incredible hopes that the complex nature of psychiatric disorders might be unravelled. However, progress in psychiatry genetics have met major difficulties that have hampered psychiatry taking advantage of the new technologies as compared to other fields, such as neurology. In this non-exhaustive review, we propose an overview from the initial evidence to the expected future, through a critical statement on the current situation.
Krebs
Marie-Odile
MO
INSERM E0117-Paris V, Université René Descartes, Paris; Hôpital Sainte-Anne, 7 Rue Cabanis, 75014 Paris, France. krebs@broca.inserm.fr
D001714:Bipolar Disorder / Q000235:genetics*; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D004200:Diseases in Twins / Q000235:genetics; D005544:Forecasting; D020022:Genetic Predisposition to Disease / Q000235:genetics; D014644:Genetic Variation; D005824:Genetics, Behavioral / Q000639:trends*; D005838:Genotype; D006801:Humans; D008957:Models, Genetic; D010641:Phenotype; D012559:Schizophrenia / Q000235:genetics*; D018433:Twin Studies as Topic