title: Elastosonography in the diagnosis of the nodular breast lesions: preliminary report.
abstract: OBJECTIVE
  To assess the diagnostic accuracy of elastography in characterising nodular breast lesions.
  
  
  METHODS
  A total of 82 patients who received mammographic, ultrasonographic and elastographic evaluation in a single session at two Italian centres (Dept of Radiology, Az. Ospedali Riuniti, Ancona, and Ospedale Valduce, Como, Italy) between January and August 2004 according to identical protocols exhibited 91 nodules that were subjected to cytological/histological examination. Lesions were classified and scored and the sensitivity and specificity of elastography calculated.
  
  
  RESULTS
  Overall sensitivity and specificity were 79% and 89%, respectively. However, sensitivity was 86% and 65% and specificity 100% and 62% for lesions < 2 cm and > 2 cm in diameter, respectively. Despite the small sample and the fact that it does not include the full range of cell types, tumour cell composition seemed to affect accuracy.
  
  
  CONCLUSIONS
  Elastography is easy and rapid to perform. Larger studies are needed to establish semiological patterns; despite the small patient sample, these data provide an interesting contribution.
authors.affiliation: Istituto di Radiologia, Università Politecnica delle Marche, Azienda Mista Ospedali Riuniti, Facoltà di Medicina, Ancona. gm.giuseppetti@ao-umbertoprimo.marche.it
authors.forename: Gian Marco
authors.initials: GM
authors.lastname: Giuseppetti
authors.forename: Alberto
authors.initials: A
authors.lastname: Martegani
authors.forename: Barbara
authors.initials: B
authors.lastname: Di Cioccio
authors.forename: Silvia
authors.initials: S
authors.lastname: Baldassarre
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D001706:Biopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000473:pathology; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012680:Sensitivity and Specificity; D012984:Software; D016217:Ultrasonography, Mammary