title: [Prognostic value of the uterine doppler velocimetry at 20-24 gestation weeks for PIH and IUGR development in pregnancy].
abstract: OBJECTIVE
  Pathogenesis of pregnancy induced hypertension and intrauterine growth retardation is strictly connected with poor supply of the feto-maternal unit with well oxygenated blood rich in all nutritional substances. Monitoring of the pregnancy course and normal values estimation in the group of non-complicated pregnancies allows us to get PIH and IUGR prediction values of the uterine velocimetry.
  
  
  METHODS
  Main aims of the study were: estimation of the normal values for utcrine velocimetry in II and III trimester of pregnancy (S/D, RI, and PI); analysis of the prognostic usefulness of these parameters (between 20-24 gestation weeks) and importance of notch in FVW for development of PIH and IUGR later in pregnancy.
  
  
  RESULTS
  We observed a decrease of uterine velocimetry parameters (mean values) in the course of normal pregnancy (19-40 gestation weeks). The sensitivity of the notch observation in 20-24 week in the uterine FVW for the prediction of PIH and/or IUGR (all study group) in the III trimester was 73,68% and the specificity 97,15%. The prognostic value of the examined pathology markers at 20-24 weeks was for notch or R >90% - 79,69% and notch or PI >90% - 70,31%.
  
  
  CONCLUSIONS
  Normal pregnancy is characterized by a decrease of the uterine S/D, RI and PI values. There is a significant dependence between high values of S/D, RI, PI and observation of notch in uterine FVW at 20-24 weeks and development of PIH and IUGR in the course of pregnancy. Doppler velocimetry of the uterine blood flow as a screening method at 20-24 weeks allows to get a prognosis about further course of pregnancy in the groups of low- and high-risk for PIH and IUGR development.
authors.affiliation: Instytut Ginekologii i Połoznictwa Uniwersytetu Medycznego w Lodzi. advances@csk.am.lodz.pl
authors.forename: Piotr
authors.initials: P
authors.lastname: Sieroszewski
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Guzowski
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D015331:Cohort Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging*; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D010920:Placenta / Q000098:blood supply / Q000503:physiopathology; D011044:Poland; D011237:Predictive Value of Tests; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011379:Prognosis; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal / Q000379:methods; D014469:Umbilical Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging*