Modified histologic technique for processing metallic coil-bearing tissue.
We developed a modified paraffin-embedding histologic technique for processing metallic coil-bearing aneurysm tissues. This modified technique was successfully employed for processing platinum coil-bearing tissue for 30 rabbit aneurysms and 6 swine aneurysms. This technique for sectioning coil-bearing aneurysms resulted in little or no tissue distortion and permitted good preservation of morphology and application of multiple advanced staining techniques. This technique is considered beneficial for studying the molecular mechanisms of aneurysm healing after coiling.
Dai
Daying
D
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Ding
Yong Hong
YH
Danielson
Mark A
MA
Kadirvel
Ramanathan
R
Lewis
Debra A
DA
Cloft
Harry J
HJ
Kallmes
David F
DF
D000818:Animals; D002340:Carotid Artery Diseases / Q000473:pathology* / Q000628:therapy*; D017536:Carotid Artery, Common; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D006652:Histological Techniques / Q000592:standards; D002532:Intracranial Aneurysm / Q000473:pathology* / Q000628:therapy*; D016612:Paraffin Embedding; D010984:Platinum; D011817:Rabbits; D013194:Staining and Labeling; D013552:Swine
D010984:Platinum