title: Synthesis of methyl 4'-O-methyl-13C12-beta-D-cellobioside from 13C6-D-glucose. Part 1: reaction optimization and synthesis.
abstract: A high yielding synthetic route for methyl 4'-O-methyl-beta-D-cellobioside starting from d-glucose was established. The reaction conditions optimized with nonlabeled materials were used for the synthesis of methyl 4'-O-methyl-13C12-beta-D-cellobioside, a compound having more than 99% 13C enrichment at each of the twelve pyranose carbon atoms. The labeled compound is required to study the hydrogen bond network of cellodextrins and cellulose by CPMAS NMR experiments.
authors.affiliation: Department of Chemistry and Christian-Doppler Laboratory, University of Natural Resources and Applied Life Sciences Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Yoneda
authors.forename: Toshinari
authors.initials: T
authors.lastname: Kawada
authors.forename: Thomas
authors.initials: T
authors.lastname: Rosenau
authors.forename: Paul
authors.initials: P
authors.lastname: Kosma
mesh_terms: D002247:Carbon Isotopes; D002475:Cellobiose / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D005947:Glucose / Q000737:chemistry*; D007553:Isotope Labeling / Q000379:methods
chemical_list: D002247:Carbon Isotopes; C506679:methyl 4'-O-methylcellobioside; D002475:Cellobiose; D005947:Glucose