Determinants of low EPSP attenuation in primary dendrites of mitral cells: modeling study.
Efficiency of synaptic potential propagation through neurons depends mainly on their membrane properties and intracellular resistivity. We use a morphologically realistic compartmental model of a mitral cell and data obtained from whole-cell patch-clamp and voltage-imaging experiments to explore passive parameter space in which reported low EPSP attenuation is observed.
Popović
Marko
M
Center for Multidisciplinary Studies, University of Belgrade, Serbia and Montenegro. tica@ibiss.bg.ac.yu
Djurisić
Maja
M
Zecević
Dejan
D
D000818:Animals; D003712:Dendrites / Q000502:physiology*; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology*; D007091:Image Processing, Computer-Assisted; D008564:Membrane Potentials / Q000502:physiology; D008959:Models, Neurological; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D009830:Olfactory Bulb / Q000166:cytology*; D018408:Patch-Clamp Techniques; D051381:Rats