title: Optical technologies for cervical neoplasia: update of an NCI program project grant.
abstract: Cervical cancer is the second most common cancer in women worldwide and the leading cause of cancer mortality in women in developing countries. In the United States, over $6 billion is spent annually in the evaluation and treatment of low-grade lesions, many of which do not develop into full-blown cancer. In developing countries, however, the chief concern is that cervical cancer goes undetected because of the cost of testing and the lack of resources and trained personnel to screen and diagnose the disease. The goal of the National Cancer Institute Program Project Grant CA82710 is to assess the emerging technologies of fluorescence and reflectance spectroscopy and quantitative cytology and histopathology for the diagnosis of cervical neoplasia. All of these technologies should decrease mortality, morbidity, and the cost of treating cervical cancer.
authors.affiliation: The Center for Biomedical Engineering, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. mfollen@mdanderson.org
authors.forename: Michele
authors.initials: M
authors.lastname: Follen
authors.forename: Stacy
authors.initials: S
authors.lastname: Crain
authors.forename: Calum
authors.initials: C
authors.lastname: MacAulay
authors.forename: Karen
authors.initials: K
authors.lastname: Basen-Engquist
authors.forename: Scott B
authors.initials: SB
authors.lastname: Cantor
authors.forename: Dennis
authors.initials: D
authors.lastname: Cox
authors.forename: E Neely
authors.initials: EN
authors.lastname: Atkinson
authors.forename: Nick
authors.initials: N
authors.lastname: MacKinnon
authors.forename: Martial
authors.initials: M
authors.lastname: Guillaud
authors.forename: Rebecca
authors.initials: R
authors.lastname: Richards-Kortum
mesh_terms: D019295:Computational Biology; D005260:Female; D006801:Humans; D008857:Microscopy, Interference / Q000379:methods* / Q000639:trends; D009316:National Institutes of Health (U.S.); D012109:Research Support as Topic; D012924:Social Conditions; D013050:Spectrometry, Fluorescence / Q000379:methods* / Q000639:trends; D014481:United States; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*