Serological analysis of serum samples from humans exposed to avian H7 influenza viruses in Italy between 1999 and 2003.
We evaluated the potential for avian-to-human transmission of low pathogenic avian influenza (LPAI) and highly pathogenic avian influenza (HPAI) H7N1 and LPAI H7N3 viruses that were responsible for several outbreaks of influenza in poultry in Italy between 1999 and 2003. A serological survey of poultry workers was conducted by use of a combination of methods. Evidence of anti-H7 antibodies was observed in 3.8% of serum samples collected from poultry workers during the period in 2003 when LPAI H7N3 virus was circulating. These findings highlight the need for surveillance in people occupationally exposed to avian influenza viruses, so that they can be monitored for the risk of avian-to-human transmission during outbreaks of avian influenza caused by both LPAI and HPAI viruses.
Puzelli
Simona
S
Department of Infectious, Parasitic and Immuno-Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy.
Di Trani
Livia
L
Fabiani
Concetta
C
Campitelli
Laura
L
De Marco
Maria Alessandra
MA
Capua
Ilaria
I
Aguilera
Jean Francois
JF
Zambon
Maria
M
Donatelli
Isabella
I
D000382:Agricultural Workers' Diseases / Q000453:epidemiology / Q000821:virology; D000818:Animals; D000914:Antibodies, Viral; D004196:Disease Outbreaks / Q000662:veterinary*; D018562:Disease Transmission, Infectious / Q000662:veterinary; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics; D006801:Humans; D053126:Influenza A Virus, H7N7 Subtype / Q000276:immunology / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000453:epidemiology / Q000635:transmission*; D007251:Influenza, Human / Q000635:transmission / Q000821:virology*; D007558:Italy / Q000453:epidemiology; D011200:Poultry; D016036:Seroepidemiologic Studies; D015047:Zoonoses / Q000453:epidemiology / Q000635:transmission*
D000914:Antibodies, Viral; D019267:Hemagglutinin Glycoproteins, Influenza Virus