title: [Goiter transformation as a risk factor of the development of bronchial asthma in children under the influence of natural and technogenic factors of the environment].
abstract: The paper deals with the comparative characterization of the prevalence of goiter transformation in children with bronchial asthma (BA) in relation to the level of a technogenic load and natural iodine deficiency in case of the Perm Region. There was a wide distribution of goiter transformation in children, which did not correspond to natural iodine supply in the Perm Region, suggesting the contribution of anthropogenic strumogenic factors to the formation of goiter endemia. There was a high prevalence of thyromegaly in children with BA as compared with those with another disease and its high the incidence as man-made pollution increased particularly in the areas exposed to a combination of natural and technogenic factors as compared in relatively pure areas. The findings suggest that goiter transformation is a marker of ecological ill-being and an additional serious risk factor of the development and prolonged course of BA in predisposed children.
authors.forename: A A
authors.initials: AA
authors.lastname: Akatova
authors.forename: N V
authors.initials: NV
authors.lastname: Zaĭtseva
authors.forename: I I
authors.initials: II
authors.lastname: Balabolkin
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Ustinova
authors.forename: M A
authors.initials: MA
authors.lastname: Zemlianova
authors.forename: O V
authors.initials: OV
authors.lastname: Vozgoment
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D004785:Environmental Pollutants / Q000009:adverse effects*; D005260:Female; D006043:Goiter, Endemic / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007455:Iodine / Q000172:deficiency*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
chemical_list: D004785:Environmental Pollutants; D007455:Iodine