title: Use of handheld computers for assessment of prefrontal cortex function in patients with phenylketonuria.
abstract: Assessment of prefrontal brain cortex function can be helpful in treatment monitoring in patients with phenylketonuria. We aimed to assess the usefulness of computerized neuropsychological tests developed for handheld computers for this purpose. We observed worse test performance among persons with blood phenylalanine concentrations exceeding the recommended range. Use of handheld computers was assessed by patients and by doctors as interesting, not time-consuming and convenient. This method can be helpful during routine follow-up visits.
authors.affiliation: Department of Pediatrics, Jagiellonian University, ul. Wielicka 265, 30-663 Kraków, Poland. AgMir@mp.pl
authors.forename: M
authors.initials: M
authors.lastname: Bik-Multanowski
authors.forename: R
authors.initials: R
authors.lastname: Mozrzymas
authors.forename: M
authors.initials: M
authors.lastname: Nowacka
authors.forename: U
authors.initials: U
authors.lastname: Borawska-Kowalczyk
authors.forename: A
authors.initials: A
authors.lastname: Lange
authors.forename: E
authors.initials: E
authors.lastname: Starostecka
authors.forename: B
authors.initials: B
authors.lastname: Didycz
authors.forename: L
authors.initials: L
authors.lastname: Kaluzny
authors.forename: M
authors.initials: M
authors.lastname: Gizewska
authors.forename: E
authors.initials: E
authors.lastname: Szynaka
authors.forename: A
authors.initials: A
authors.lastname: Szymczakiewicz-Multanowska
mesh_terms: D000293:Adolescent; D000328:Adult; D001292:Attitude to Computers; D002648:Child; D034201:Computers, Handheld; D006801:Humans; D009483:Neuropsychological Tests; D010649:Phenylalanine / Q000378:metabolism*; D010661:Phenylketonurias / Q000503:physiopathology / Q000523:psychology*; D017397:Prefrontal Cortex / Q000503:physiopathology*
chemical_list: D010649:Phenylalanine