[Investigation of enterovirus in cases of aseptic meningitis syndrome of Belém, PA].
With the objective of isolating and identifying enteroviral serotypes, which are the most frequent etiologic agents of aseptic meningitis syndrome, cerebrospinal fluid samples were studied from patients referred to the health unit in the City of Belém (State of Pará, Brazil), from March 2002 to March 2003. The samples were inoculated in RD and HEp-2 cells line, and the positive were identified by neutralization test or indirect immunofluorescence. Out of 249 samples, 33 (13.2%) were positive 57.6% (n = 19) in patients under 11 years of age (p < 0.03) and predominantly (72.7%) in males (p < 0.008). The serotypes isolated were: Echovirus 30 (n = 31), Coxsackievirus B5 (n = 1) and Echovirus 30 and 4. In conclusion, this type of study also serves to determine the national picture, which is still little defined, regarding the most prevalent viral agents in AMS cases.
Lamarão
Letícia Martins
LM
Faculdade de Medicina, Universidade Federal da Bahia, Salvador, BA.
Gomes
Maria de Lourdes Contente
Mde L
Ferreira
Lauze Lee Alves
LL
Fonseca
Cleide Mara
CM
Araújo
Lia C B
LC
Santana
Marquete B
MB
Tavares-Neto
José
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004770:Enterovirus / Q000145:classification* / Q000302:isolation & purification; D004769:Enterovirus Infections / Q000134:cerebrospinal fluid / Q000821:virology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid / Q000821:virology*; D008875:Middle Aged