title: Ventricular fibrillation refractory to ICD therapy.
abstract: A 14-year-old boy was admitted for the evaluation of recurrent syncope. His ECG on admission revealed a sinus rhythm with an undetermined QRS axis, T wave inversion at leads V3, V4 and abnormal q at leads I, aVL, V5 and V6. However, no underlying disease could be detected by any morphological examination. Programmed ventricular stimulation also induced no ventricular tachycardia or fibrillation (VF). Only signal-averaged ECG showed ventricular late potential and the cause of syncope was not clarified. As his brother with a similar ECG had died suddenly, he was prophylactically treated with an ICD. However, 14 months later he died suddenly after playing a video game. The ICD recorded VF, which was not converted despite 6 cardioversion attempts by the ICD. Progression of myocardial damages and/or elevation of defibrillation threshold may have been the cause of unsuccessful cardioversion.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yasuda
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Sasaki
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Kawano
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nakazato
authors.forename: Takashi
authors.initials: T
authors.lastname: Tokano
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Daida
mesh_terms: D000293:Adolescent; D016757:Death, Sudden, Cardiac; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D006801:Humans; D008297:Male; D014693:Ventricular Fibrillation / Q000503:physiopathology / Q000628:therapy*