[Cardiac events and 5-year survival after acute coronary syndromes].
OBJECTIVE
To evaluate the incidence of cardiac events and survival in patients with first acute coronary syndromes during 5-year period.


RESULTS
Data on 732 patients admitted with first acute coronary syndrome were collected in a database. During hospitalization period 45.4% of the patients received reperfusion therapy. During follow-up period (4.49+/-2.1 years) 215 (29.4%) patients had cardiac events: 15.3%--myocardial revascularization, 8.1%--repeated myocardial infarction, 11.5%--cardiovascular deaths. The highest (5%) mortality rate was during first year, whereas during the following four years--1.5% annually. Kaplan-Meier analysis for survival free of cardiovascular death revealed that mortality rates were higher among patients who were > or =65 years old (long-rank test, p=0.02); had heart failure at admission (p=0.003), left ventricular ejection fraction <40% (p=0.04), significance diastolic dysfunction (p=0.035), III-IV degrees mitral regurgitation (p=0.00006); did not received reperfusion therapy (p=0.007).


CONCLUSIONS
The analysis of this long-term follow-up data shows that the patients with acute coronary syndromes carry a high risk of death and need better treatment strategies to reduce risk.
Zaliūnas
Remigijus
R
1Department of Cardiology, Kaunas University of Medicine, Kaunas, Lithuania.
Babarskiene
Marija Rūta
MR
Luksiene
Dalia
D
Vencloviene
Jone
J
Slapikiene
Birute
B
Milvidaite
Irena
I
Statkeviciene
Eugenija Audrone
EA
Linoniene
Vita
V
D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D000789:Angina, Unstable / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000601:surgery; D017023:Coronary Angiography; D003627:Data Interpretation, Statistical; D016757:Death, Sudden, Cardiac / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000601:surgery; D009204:Myocardial Revascularization; D012008:Recurrence; D012307:Risk Factors; D013318:Stroke Volume; D016019:Survival Analysis; D013577:Syndrome; D013997:Time Factors