title: [Effect of Guliu capsule combined with 89Sr therapy on metastatic bone tumor].
abstract: OBJECTIVE
  To evaluate the therapeutic effects of Guliu capsule (GLC) combined with 89Sr in treating metastatic bone tumors.
  
  
  METHODS
  On the basis of random sampling and grouping, 50 patients with metastatic bone tumors were selected to receive combined treatment with GLC and (89)Sr with another 50 patients recruited for (89)Sr treatment alone. The therapeutic effect of the therapies were evaluated according to the relief of ostalgia and quality-of life (QOF), local bone metabolism and hematopoietic function of the bone marrow.
  
  
  RESULTS
  The efficacy rate of GLC+89Sr and (89)Sr in relieving ostalgia was 94.0% and 76.0%, and the rate of QOF improvement and stabilization was 94.0% and 74.0%, respectively, both showing significant difference between the two groups (P<0.05). The effect of the two treatment protocols on local bone metabolism and their hemotoxicity were also significantly different (P<0.05, P<0.01, respectively).
  
  
  CONCLUSIONS
  Combined treatment with GLC and (89)Sr is effective for metastatic bone tumor and improves the patient's QOF with enhanced ostalgia relief rate and decreased hemotoxicity.
authors.affiliation: Department of Integrated Traditional Chinese and Western Medicine, Guangzhou Tumor Hospital, Guangzhou 510095, China. sxc118@126.com
authors.forename: Xu-chun
authors.initials: XC
authors.lastname: Su
authors.forename: Yong-lin
authors.initials: YL
authors.lastname: Wang
authors.forename: Xue-yan
authors.initials: XY
authors.lastname: Yang
authors.forename: Cheng-lin
authors.initials: CL
authors.lastname: Liu
authors.forename: Bin-chuan
authors.initials: BC
authors.lastname: Yan
authors.forename: Jia-xin
authors.initials: JX
authors.lastname: Kong
authors.forename: Xian-lu
authors.initials: XL
authors.lastname: Song
authors.forename: Kun
authors.initials: K
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D002214:Capsules; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013326:Strontium Radioisotopes / Q000627:therapeutic use*
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D013326:Strontium Radioisotopes