title: [Outcome of non-pharmacologic treatment in a gestational diabetic woman with high insulin resistance HOMA-IR index and allergy to human insulin. Case report].
abstract: Gestational diabetes is a syndrome of significant pathophysiological and clinical heterogeneity. This type of diabetes mellitus can be treated with diet, exercise and insulin in cases of unsatisfactory results of nonpharmacologic treatment. It has been reported the case of a 28-year -old female with gestational diabetes treated with high doses of insulin (128 U/per day) on four injections regimens. During the therapy allergic type III reactions to human insulin preparations (Ultratard HM, Actrapid HM Humulin U, Humulin R, Humalog) has been occurred at the injection site. The insulin was omitted. We applied diet modification and 15-30 minutes walking before meals till the afternoon with god metabolic control. High insulin resistance index HOMA-IR, type 2 diabetes history in both parents god metabolic control of nonpharmacologic treatment, and impaired glucose tolerance after post-partum may suggest, the early stage of diabetes type 2 in presented case.
authors.affiliation: Katedra i Klinika Gastroenterologii Chorób Naczyń i Chorób Wewnetrznych AM w Bydgoszczy.
authors.forename: Alina
authors.initials: A
authors.lastname: Sokup
authors.forename: Maciej
authors.initials: M
authors.lastname: Swiatkowski
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Tyloch
authors.forename: Wiesław
authors.initials: W
authors.lastname: Szymanski
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis; D016640:Diabetes, Gestational / Q000178:diet therapy / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D004035:Diet Therapy / Q000379:methods; D003875:Drug Eruptions / Q000209:etiology; D015444:Exercise; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D007328:Insulin / Q000009:adverse effects; D007333:Insulin Resistance; D061389:Insulin, Regular, Pork; D010353:Patient Education as Topic / Q000379:methods; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D061389:Insulin, Regular, Pork; C023501:Insulin, Ultratard; C000006:insulin, neutral