Granular parakeratotic acanthoma.
Granular parakeratosis was originally described as a dermatosis confined to the axillae that histopathologically shows characteristic findings in the cornified layer consisting of parakeratotic corneocytes housing keratohyaline granules. Since the original description of this entity, non-intertriginous examples and even incidental foci of granular parakeratotic corneocytes in association with other dermatoses have been recognized. This report details the findings of a previously unreported entity that we are naming granular parakeratotic acanthoma, which is fundamentally akin to acantholytic dyskeratotic acanthoma and epidermolytic acanthoma (ie, a solitary keratosis that histopathologically displays features indicated in its name).
Resnik
Kenneth S
KS
Institute for Dermatopathology in Conshohocken, Pennsylvania 19428, USA. kresnik@ameripath.com
Kantor
Gary R
GR
DiLeonardo
Mario
M
D049309:Acanthoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010241:Parakeratosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*