title: Children of a cohort of depressed patients 25 years on: identifying those at risk.
abstract: OBJECTIVE
  Factors associated with psychological outcome in children of patients with depression have been examined piecemeal, with emphasis on young rather than adult children. We hypothesized that psychological morbidity in adult children of patients with depression would be associated with characteristics of the children, their parents and their family relationships.
  
  
  METHODS
  Factors predicting psychopathology in children (n = 94) of a cohort of patients with depression, admitted to a teaching hospital 25 years earlier, were examined using logistic regression.
  
  
  RESULTS
  Psychological morbidity in children was predicted by their being younger at parent's admission, their perception of the depressed parent as more controlling and chronicity of the parent's depression. Correlations between child characteristics, parent illness and family relationship variables showed systemic interactions between parental illness, child psychopathology and family relationships.
  
  
  CONCLUSIONS
  Chronicity (though neither recurrence nor severity) of parent depression and younger children's age at the time of parental admission for depression were associated with psychological morbidity in the children in adulthood. The interaction between child psychopathology, parental illness and family relationships emphasizes the need for a systemic, family focus in the treatment of depression.
authors.affiliation: Academic Department for Old Age Psychiatry, Euroa Centre, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Carmelle
authors.initials: C
authors.lastname: Peisah
authors.forename: Henry
authors.initials: H
authors.lastname: Brodaty
authors.forename: Georgina
authors.initials: G
authors.lastname: Luscombe
authors.forename: Kaarin J
authors.initials: KJ
authors.lastname: Anstey
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D016241:Child of Impaired Parents / Q000523:psychology* / Q000706:statistics & numerical data*; D002675:Child, Preschool; D015331:Cohort Studies; D003866:Depressive Disorder / Q000523:psychology*; D005195:Family Relations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology* / Q000523:psychology; D008875:Middle Aged; D010287:Parent-Child Relations; D010290:Parents / Q000523:psychology*; D010465:Perception / Q000502:physiology; D012307:Risk Factors; D012737:Sex Factors