title: Immune tolerance induction with highly purified plasma-derived factor VIII containing von Willebrand factor in hemophilia A patients with high-responding inhibitors.
abstract: We retrospectively evaluated the efficacy of immune tolerance induction (ITI) in a homogenous cohort of eight patients with constitutive severe hemophilia A with high-responding factor VIII (FVIII) inhibitors using Facteur VIII-LFB/Factane, a highly purified FVIII concentrate containing von Willebrand factor (VWF).
authors.forename: Frédérique
authors.initials: F
authors.lastname: Orsini
authors.forename: Chantal
authors.initials: C
authors.lastname: Rotschild
authors.forename: Philippe
authors.initials: P
authors.lastname: Beurrier
authors.forename: Albert
authors.initials: A
authors.lastname: Faradji
authors.forename: Jenny
authors.initials: J
authors.lastname: Goudemand
authors.forename: Benoît
authors.initials: B
authors.lastname: Polack
mesh_terms: D002648:Child; D002675:Child, Preschool; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000276:immunology* / Q000378:metabolism; D006467:Hemophilia A / Q000097:blood / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D007223:Infant; D012189:Retrospective Studies; D014842:von Willebrand Diseases / Q000097:blood / Q000276:immunology; D014841:von Willebrand Factor / Q000037:antagonists & inhibitors* / Q000276:immunology* / Q000378:metabolism
chemical_list: D014841:von Willebrand Factor; D005169:Factor VIII