title: Antidepressants and psychotherapy: a clinical research review.
abstract: This review focuses on information concerning antidepressants and psychotherapy in the treatment of both acute and chronic forms of unipolar depression in the English language literature. In it, we address the use of combination therapy, both from the outset of treatment and in a variety of sequences, ie, we examine the potential advantages of adding a targeted psychotherapy to an incompletely effective pharmacotherapy and the potential advantages of adding pharmacotherapy to an incompletely effective psychotherapy. The number of research reports available to address these questions is small relative to their importance for clinical practice. There is a clear need for more information about the relative efficacy of pharmacotherapy-psychotherapy combinations or sequences versus either pharmacotherapy or psychotherapy provided as monotherapies.
authors.affiliation: University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic PA 15213, USA. franke@upmc.edu
authors.forename: Ellen
authors.initials: E
authors.lastname: Frank
authors.forename: Danielle
authors.initials: D
authors.lastname: Novick
authors.forename: David J
authors.initials: DJ
authors.lastname: Kupfer
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003863:Depression / Q000628:therapy*; D006801:Humans; D011613:Psychotherapy
chemical_list: D000928:Antidepressive Agents