title: Interaction between haptoglobin subtypes and AB0 blood groups in a Bengalee population.
abstract: Blood samples from 621 individuals of a Caste Hindu Population from West Bengal (India) were investigated in an attempt to find out an association between the AB0 blood groups and Haptoglobin (HP) subtypes. AB0 blood grouping was done on the basis of the agglutination test with standard anti-sera. Haptoglobin subtyping only for the HP*1 allele was done by Polyacrylamide Gel Electrophoresis (PAGE). A significant association was found with a significantly lower HP*1S allele frequency in blood group 0 versus other AB0 blood groups. A comparatively higher allele frequency of HP*1S was found in this population sample. An inverse relationship between HP*1S and HP*2 has been revealed in each blood group. It appears that the major portion of HP*1 alleles in the A, B, and AB blood groups belongs to the HP*1S allele compared to that of the 0 blood group.
authors.affiliation: Department of Anthropology, University of Calcutta, Calcutta, India. abanthro@caluniv.ac.in
authors.forename: Arup Ratan
authors.initials: AR
authors.lastname: Bandyopadhyay
authors.forename: Jayita Ghoshal
authors.initials: JG
authors.lastname: Roy
mesh_terms: D000017:ABO Blood-Group System / Q000145:classification* / Q000235:genetics*; D000328:Adult; D002874:Chromosome Mapping; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D010641:Phenotype; D040641:Quantitative Trait Loci / Q000235:genetics*; D013223:Statistics as Topic
chemical_list: D000017:ABO Blood-Group System; C485359:HP protein, human; D006242:Haptoglobins