title: Associations between dimensions of job stress and biomarkers of inflammation and infection.
abstract: OBJECTIVE
  The objective of this study was to examine associations between dimensions of job stress and indicators of chronic inflammation and infection.
  
  
  METHODS
  Within a subsample from the BELSTRESS study of 892 male subjects free of cardiovascular disease, dimensions of job stress from the job demand-control-support model were related to biomarkers of inflammation (plasma fibrinogen concentrations, high-sensitivity C-reactive protein, and serum amyloid A) and infection (titers against Chlamydia pneumoniae, cytomegalovirus, and Helicobacter pylori).
  
  
  RESULTS
  A negative association was found between job control and plasma fibrinogen concentration, independent from age, education, occupation, body mass index, smoking, alcohol consumption, and use of lipid-lowering and antihypertensive medication. Higher social support at work was independently related to an increased risk of positive titers against cytomegalovirus.
  
  
  CONCLUSIONS
  Results confirm previous findings regarding elevated plasma fibrinogen and low job control.
authors.affiliation: Department of Public Health, Ghent University, University Hospital, Belgium. els.clays@UGent.be
authors.forename: Els
authors.initials: E
authors.lastname: Clays
authors.forename: Dirk
authors.initials: D
authors.lastname: De Bacquer
authors.forename: Joris
authors.initials: J
authors.lastname: Delanghe
authors.forename: France
authors.initials: F
authors.lastname: Kittel
authors.forename: Lieve
authors.initials: L
authors.lastname: Van Renterghem
authors.forename: Guy
authors.initials: G
authors.lastname: De Backer
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D002908:Chronic Disease; D015331:Cohort Studies; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D007239:Infections / Q000209:etiology*; D007249:Inflammation; D007587:Job Description; D008297:Male; D008875:Middle Aged; D016272:Occupational Health; D013315:Stress, Psychological
chemical_list: D015415:Biomarkers