Combining two-directional synthesis and tandem reactions: desymmetrisation by intramolecular cycloaddition/triazoline fragmentation.
A tandem azide formation/intramolecular cycloaddition/triazoline fragmentation/Michael addition, which results in a non-symmetrical quinolizidine from an acyclic symmetrical precursor, is presented.
Rejzek
Martin
M
School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, UK NR4 7TJ.
Stockman
Robert A
RA
van Maarseveen
Jan H
JH
Hughes
David L
DL