[Histoplasmoma as isolated central nervous system lesion in an immunocompetent patient].
The cerebral lesions are uncommon in patients with histoplasmosis, occurring more frequently in the disseminated form of the disease. Rarely, the disease may present as a histoplasmoma, simulating a neoplastic lesion. The histoplasmoma as the only manifestation of this infection in immunocompetent patients is even rarer. This case report describes a 13 year-old male patient with headache, vomit, low visual acuity and auditive deficit on the left, and paresis on the right. The magnetic resonance image showed an expansible lesion in the thalamic, hypothalamic, and chiasmatic regions, which showed ring enhancement. The stereotactic biopsy was performed and the histological diagnosis of histoplasmosis was defined. The treatment was initiated with fluconazole. The patient showed important clinical improvement after 6 months.
Gasparetto
Emerson L
EL
Serviço de Radiologia Médica e Diagnóstico por Imagem, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil. gasparetto@hotmail.com
Carvalho Neto
Arnolfo de
Ad
Alberton
James
J
Davaus
Taisa
T
Pianovski
Mara Albonei D
MA
Yamauchi
Erica
E
Torres
Luiz F Bleggi
LF
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy / Q000379:methods; D020314:Central Nervous System Fungal Infections / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D015725:Fluconazole / Q000627:therapeutic use; D006658:Histoplasma; D006660:Histoplasmosis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013238:Stereotaxic Techniques
D000935:Antifungal Agents; D015725:Fluconazole