[Efficacy of tracrolimus 0.1% ointment in prurigo].
BACKGROUND
Potent topical corticosteroids are used the intense pruritus in prurigo diseases. Their long-term application leads to local side effects such as atrophy and telangiectasia.


METHODS
We treated 6 women (average age 64 years) with chronic prurigo with tacrolimus 0.1 % ointment (Protopic) to evaluate its efficacy in this clinical setting. Tacrolimus 0.1% ointment was applied twice a day for 4 weeks.


RESULTS
After one week, both clinical improvement and reduced pruritus were observed in all patients.


CONCLUSIONS
Tacrolimus 0.1% ointment represents a therapeutic option for the treatment of prurigo.
Lee
Hae-Hyuk
HH
Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin.
Sterry
Wolfram
W
Worm
Margitta
M
D000368:Aged; D000369:Aged, 80 and over; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D009824:Ointments; D011536:Prurigo / Q000188:drug therapy*; D016559:Tacrolimus / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus