Porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease: case report.
BACKGROUND
Chronic arsenism with Bowen's disease is often seen in patients who drink water containing a high level of arsenic. Inorganic arsenic has demonstrated an increased risk of skin cancer.


OBJECTIVE
We present a rare case of porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease.


METHODS
Report of a case and review of the literature.


RESULTS
A case of porocarcinoma arising in a patient with chronic arsenism is presented. The tumor was completely excised by means of wide excision with a 5 mm free margin. The surgical defect was reconstructed with a rhombic flap.


CONCLUSIONS
Chronic arsenism can induce various skin neoplasms, possibly including porocarcinoma.
Chen
I-Shu
IS
Department of Dermatology, Veterans General Hospital, Kaohsiung, Taiwan. chenishu@sina.com.tw
Kuo
Hung-Wen
HW
Eng
Hock-Liew
HL
D020261:Arsenic Poisoning / Q000150:complications*; D001913:Bowen's Disease / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D004439:Eccrine Glands; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D013544:Sweat Gland Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery