[Neural correlates of priming in vision: evidence from neuropsychology and neuroimaging].
When we look around us, we are overall more likely to notice objects that we have recently looked at; an effect known as priming. For example, when the color or shape of a visual search target is repeated, observers find the target faster than otherwise. Here I summarize recent research undertaken to uncover the temporary changes in brain activity that accompany these priming effects. In light of the fact that priming seems to have a large effect on how attention is allocated, we investigated priming effects in a visual search task on patients suffering from the neurological disorder "hemispatial neglect" in which patients typically fail to notice display items in one of their visual hemifields. Priming of target color was relatively normal for these patients, while priming of target location seemed to require awareness of the briefly presented visual search target. An experiment with functional magnetic resonance imaging of normal observers revealed that both color and location priming had a strong modulatory influence on attentional mechanisms of the frontal and parietal cortex. Color priming was also correlated with changes in activity in visual cortex as well as color processing areas in the temporal lobe. Location priming was correlated with changes in activity near the temporo- parietal junction and lateral inferior frontal cortex, areas that have been connected with attentional capture; which ties well with our finding of deficits of location priming for the neglect patients who indeed have lesions in the temporo-parietal junction. Overall, the results confirm the tight coupling of visual attention and priming in vision, and also that the visual areas of the brain show some modulation of activity as priming develops.
Kristjánsson
Arni
A
Institute of Cognitive Neuroscience, University College London.
D001288:Attention; D001931:Brain Mapping; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000502:physiology; D010468:Perceptual Disorders / Q000503:physiopathology; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000502:physiology; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*