title: Ulcerative keratitis in mycosis fungoides.
abstract: OBJECTIVE
  To present a case of ulcerative keratitis and impending corneal perforation in a patient with mycosis fungoides (cutaneous T-cell lymphoma) that developed eyelid involvement.
  
  
  METHODS
  Case report analysis. Cultures and biopsies of the right cornea, conjunctiva, and eyelids were obtained. Biopsy tissue was examined with histologic and immunohistologic stains.
  
  
  RESULTS
  This patient with mycosis fungoides involving the eyelids developed corneal exposure and bacterial keratitis with impending corneal perforation. Lamellar keratoplasty and permanent tarsorrhaphy were performed to protect the globe from perforation.
  
  
  CONCLUSIONS
  Mycosis fungoides involving the eyelids is capable of causing severe ocular tissue injury without direct infiltration of the malignant lymphocytes. Preventative medical and surgical measures must be taken to protect the globe.
authors.affiliation: Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA. Damien_Goldberg@yahoo.com
authors.forename: Damien F
authors.initials: DF
authors.lastname: Goldberg
authors.forename: Gerald J
authors.initials: GJ
authors.lastname: Negvesky
authors.forename: Salim I
authors.initials: SI
authors.lastname: Butrus
authors.forename: Todd A
authors.initials: TA
authors.lastname: Goodglick
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D016039:Corneal Transplantation; D003320:Corneal Ulcer / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005142:Eyelid Neoplasms / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications*; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012878:Skin Neoplasms / Q000150:complications*
chemical_list: D000890:Anti-Infective Agents