title: Stapedotomy in osteogenesis imperfecta: a prospective study of 23 consecutive cases.
abstract: OBJECTIVE
  To prospectively evaluate the hearing results in surgically treated cases of stapes fixation in patients with osteogenesis imperfecta.
  
  
  METHODS
  A prospective study of osteogenesis imperfecta patients with stapes fixation.
  
  
  METHODS
  One tertiary referral center.
  
  
  METHODS
  Eighteen patients (23 ears) who underwent stapes surgery from 1994 to 2004 were prospectively included.
  
  
  METHODS
  Stapedotomy with vein graft interposition and reconstruction with a Teflon piston or a bucket handle (cup) prosthesis.
  
  
  METHODS
  Preoperative and postoperative audiometric evaluation using conventional audiometry. Air-bone gap, bone-conduction thresholds, and air-conduction thresholds were measured. Postoperative audiometry was performed at 6, 9, 12, 18, and 24 months after surgery and at a yearly interval thereafter.
  
  
  RESULTS
  Overall, a postoperative air-bone gap closure to within 10 dB was achieved in 85.7% of cases. Postoperative improvement of air-conduction thresholds superior to 20 dB was found in 57% of cases. The postoperative bone-conduction thresholds were unchanged.
  
  
  CONCLUSIONS
  This study shows that safe and successful stapedotomy is possible in cases of stapes fixation in patients with osteogenesis imperfecta.
authors.affiliation: Jean Causse Ear Clinic, Traverse de Béziers, Colombiers, France.
authors.forename: Robert
authors.initials: R
authors.lastname: Vincent
authors.forename: Benoit
authors.initials: B
authors.lastname: Gratacap
authors.forename: John
authors.initials: J
authors.lastname: Oates
authors.forename: Neil M
authors.initials: NM
authors.lastname: Sperling
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D001844:Bone Conduction / Q000502:physiology; D004429:Ear Ossicles / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010013:Osteogenesis Imperfecta / Q000601:surgery*; D011446:Prospective Studies; D012086:Reoperation; D013201:Stapes Surgery / Q000379:methods*; D017211:Treatment Failure; D016896:Treatment Outcome