Glomerulosclerosis 4 weeks after administration of adriamycin in a single dose.
The purpose of this study was the histological assessment of kidney glomerules in light microscopy after a single dose of adriamycin. Results of lab investigation showed that as soon as 4 weeks after adriamycin administration given peritoneally appears focal, segmental glomerulosclerosis.
Pedrycz
Agnieszka
A
Department of Histology and Embryology, Lab of Experimental Cytology, Skubiszewski Medical University of Lublin.
Wieczorski
Marcin
M
Czerny
Krystyna
K
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000633:toxicity*; D004317:Doxorubicin / Q000008:administration & dosage / Q000633:toxicity*; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000139:chemically induced* / Q000473:pathology; D007274:Injections, Intraperitoneal; D007678:Kidney Glomerulus / Q000187:drug effects / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin