title: Influence of different adhesive restorative materials on mutans streptococci colonization.
abstract: OBJECTIVE
  To evaluate the effect of some restorative materials on mutans streptococci colonization.
  
  
  METHODS
  Awild strain of mutans streptococci was isolated from human dental plaque and a monospecific biofilm adherent to the surfaces of 12 adhesive restorative materials (F2000, Dyract AP, Compoglass F, Z100 MP, Filtek Z250, Clearfil, Ketac-Bond, Ketac-Fil Plus, Ketac-Molar, Fuji Cap II, Fuji Bond LC and Fuji II LC) were tested. A colorimetric technique (MTT assay), based on the reduction of a yellow tetrazolium salt to a purple formazan, was used to evaluate the biomass adherent to the disk surfaces after a 24-hour growth.
  
  
  RESULTS
  One-way ANOVA showed that glass-ionomer cements (Fuji Cap II, Ketac-Bond, Ketac-Fil and Ketac-Molar) had similar antibacterial effects on mutans streptococci and were significantly more effective (P < 0.001) than all other products tested in reducing the biofilm development on their surfaces. The compomers (Dyract, Compoglass F and F 2000) showed a significantly higher value of bacterial colonization than all the other materials (P < 0.001).
authors.affiliation: University of Milan, Department of Medicine, Surgery and Dentistry San Paolo, Via Beldiletto 1/3, 20142 Milan, Italy. Eugenio.Brambilla@unimi.it
authors.forename: Eugenio
authors.initials: E
authors.lastname: Brambilla
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Cagetti
authors.forename: Massimo
authors.initials: M
authors.lastname: Gagliani
authors.forename: Luigi
authors.initials: L
authors.lastname: Fadini
authors.forename: Franklin
authors.initials: F
authors.lastname: García-Godoy
authors.forename: Laura
authors.initials: L
authors.lastname: Strohmenger
mesh_terms: D000269:Adhesives / Q000494:pharmacology*; D000704:Analysis of Variance; D001422:Bacterial Adhesion / Q000187:drug effects; D018441:Biofilms / Q000187:drug effects; D020770:Compomers / Q000494:pharmacology*; D003188:Composite Resins / Q000494:pharmacology*; D003773:Dental Plaque / Q000382:microbiology; D003793:Dental Restoration, Permanent; D005899:Glass Ionomer Cements / Q000494:pharmacology*; D006801:Humans; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D000269:Adhesives; D020770:Compomers; D003188:Composite Resins; D005899:Glass Ionomer Cements