title: Buschke-Löwenstein tumor in childhood: a case report.
abstract: Buschke-Löwenstein tumor or giant condyloma is a warty verrucous lesion, characterized by slow growth, locally infiltrating and disfiguring lesions. Despite its benign histological appearance and low risk of metastasis, Buschke-Löwenstein tumor is an intermediate lesion between condyloma acuminatum and verrucous carcinoma. It has been linked to human papilloma virus, mainly subtypes 6 and 11. Other factors implicated in this disease include poor hygiene, chronic irritation, promiscuity, and cellular immunocompromised states. It rarely occurs in children. The first line of treatment is radical surgical excision with or without adjuvant chemotherapy. We report the case of a 12-year-old girl with a giant perianal condyloma that was treated with surgical excision and a 6-week course of 5-fluorouracil beginning 6 weeks after surgery, with excellent functional and cosmetic results.
authors.affiliation: Department of Pediatric Surgery, Juan I. Menchaca's Civil Hospital, Guadalajara, Jalisco 44340, Mexico. ggaby03@yahoo.com
authors.forename: Gabriela
authors.initials: G
authors.lastname: Ambriz-González
authors.forename: L C
authors.initials: LC
authors.lastname: Escobedo-Zavala
authors.forename: F
authors.initials: F
authors.lastname: Carrillo de la Mora
authors.forename: A
authors.initials: A
authors.lastname: Ortiz-Arriaga
authors.forename: A
authors.initials: A
authors.lastname: Cordero-Zamora
authors.forename: A
authors.initials: A
authors.lastname: Corona-Nakamura
authors.forename: M K L
authors.initials: MK
authors.lastname: López Ramírez
authors.forename: G A
authors.initials: GA
authors.lastname: Velázquez Ramírez
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000188:drug therapy* / Q000601:surgery; D018289:Carcinoma, Verrucous / Q000188:drug therapy* / Q000601:surgery; D002648:Child; D003218:Condylomata Acuminata / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil