[Antibiotic administration in preterm delivery].
METHODS
Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor.


OBJECTIVE
We attempted to determine the effect of antibioticotherapy in mothers on congenital neonatal infection.


METHODS
The study group consisted of 1049 pregnant women with imminent preterm labor hospitalized in Clinics of The Research Institute Polish Mother's Memorial Hospital.


RESULTS
244 women delivered preterm and no significant difference in neonatal outcomes could be detected in two groups with intact membranes and preterm premature rupture of membranes.


CONCLUSIONS
The results of this study do not support the routine use of antibiotic administration in women with preterm labor.
Pieta-Dolińska
Agnieszka
A
Klinika Perinatologii, Instytutu Centrum Zdrowia Matki Polki, Lódź.
Jaczewski
Bogumił
B
Wardecka
Jadwiga
J
Woźniak
Piotr
P
Wilczyński
Jan
J
Krasomski
Grzegorz
G
Oszukowski
Przemysław
P
D000328:Adult; D019072:Antibiotic Prophylaxis / Q000379:methods*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control*; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D011256:Pregnancy Outcome / Q000453:epidemiology; D012189:Retrospective Studies; D016896:Treatment Outcome