title: Production of rhamnolipids by Pseudomonas aeruginosa.
abstract: Pseudomonas aeruginosa produces glycolipidic surface-active molecules (rhamnolipids) which have potential biotechnological applications. Rhamnolipids are produced by P. aeruginosa in a concerted manner with different virulence-associated traits. Here, we review the rhamnolipids biosynthetic pathway, showing that it has metabolic links with numerous bacterial products such as alginate, lipopolysaccharide, polyhydroxyalkanoates, and 4-hydroxy-2-alkylquinolines (HAQs). We also discuss the factors controlling the production of rhamnolipids and the proposed roles this biosurfactant plays in P. aeruginosa lifestyle.
authors.affiliation: Departamento de Bioprocesos y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Mexico City, Mexico. gloria@biomedicas.unam.mx
authors.forename: Gloria
authors.initials: G
authors.lastname: Soberón-Chávez
authors.forename: François
authors.initials: F
authors.lastname: Lépine
authors.forename: Eric
authors.initials: E
authors.lastname: Déziel
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001709:Biotechnology / Q000379:methods; D015964:Gene Expression Regulation, Bacterial; D006017:Glycolipids / Q000096:biosynthesis* / Q000737:chemistry; D006801:Humans; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D006017:Glycolipids; C418382:rhamnolipid