Circular dichroism, a powerful tool for the assessment of absolute configuration of flavonoids.
Circular dichroism is a powerful tool for establishing the absolute configuration of flavonoids and proanthocyanidin analogues. It has been utilized to study the configuration of flavanones, dihydroflavonols (3-hydroxyflavanones), flavan-3-ols, flavan-4-ols, flavan-3,4-diols, flavans, isoflavans, isoflavanones, pterocarpans, 6a-hydroxypterocarpans, rotenoids, 12a-hydroxyrotenoids, neoflavonoids, 3,4-dihydro-4-arylcoumarins, 4-arylflavan-3-ols, auronols, homoisoflavanones, proanthocyanidins, and various classes of biflavonoids. Results relevant to the correlation of circular dichroic data and the absolute configuration of the diastereoisomers of some of the above classes of compounds will be discussed.
Slade
Desmond
D
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi University, MS 38677, USA. dslade@olemiss.edu
Ferreira
Daneel
D
Marais
Jannie P J
JP
D002942:Circular Dichroism; D005419:Flavonoids / Q000737:chemistry*; D015394:Molecular Structure
D005419:Flavonoids