Infectious keratitis after overnight orthokeratology in Canada.
OBJECTIVE
To report 3 cases of infectious keratitis related to overnight orthokeratology use.


METHODS
Retrospective case observation.


RESULTS
All 3 patients were using overnight orthokeratology lenses when they presented with unilateral corneal ulcers. The organisms isolated were Acanthamoeba, Pseudomonas aeruginosa, and Serratia marcescens. The clinical presentation and treatment of each case is presented.


CONCLUSIONS
Overnight orthokeratology use may be associated with infectious keratitis despite the use of more oxygen-permeable materials and improved lens design. Patient education with informed consent, appropriate lens care, and meticulous follow-up is important. Because this complication is potentially sight threatening, orthokeratology requires further analysis and evaluation to establish its safety. The cases here are the first few reported cases in North America.
Yepes
Natasha
N
Department of Ophthalmology and Vision Science, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada.
Lee
Sao-Bing
SB
Hill
Vivian
V
Ashenhurst
Mike
M
Saunders
Patrick P R
PP
Slomovic
Allan R
AR
D015823:Acanthamoeba Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002170:Canada; D002648:Child; D018639:Contact Lens Solutions; D003261:Contact Lenses / Q000009:adverse effects* / Q000382:microbiology / Q000469:parasitology; D003315:Cornea / Q000382:microbiology / Q000469:parasitology; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012030:Refractive Errors / Q000628:therapy; D012189:Retrospective Studies; D016868:Serratia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012706:Serratia marcescens / Q000302:isolation & purification
D000890:Anti-Infective Agents; D000981:Antiprotozoal Agents; D018639:Contact Lens Solutions