title: Human chorionic gonadotropin in cervical fluid as a predictor of miscarriage.
abstract: OBJECTIVE
  To determine whether the concentration of hCG in cervical fluid can predict miscarriage during early pregnancy.
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Ninety-nine women with singleton pregnancies, 17 of whom suffered a miscarriage.
  
  
  METHODS
  None.
  
  
  METHODS
  Miscarriage and the cervical fluid/serum hCG concentration ratio.
  
  
  RESULTS
  With a cutoff value of 1.0, the sensitivity, specificity, and positive and negative predictive values of the cervical fluid/serum hCG concentration ratio for predicting miscarriage were 88.2%, 94.9%, 83.3%, and 96.6%, respectively.
  
  
  CONCLUSIONS
  The cervical fluid/serum hCG concentration ratio might be a useful predictor of miscarriage during early pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, Japan. takata@hama-med.ac.jp
authors.forename: Kayoko
authors.initials: K
authors.lastname: Takata
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Suganuma
authors.forename: Hisae
authors.initials: H
authors.lastname: Wada
authors.forename: Kinya
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Kimiya
authors.initials: K
authors.lastname: Kitamura
authors.forename: Naohiro
authors.initials: N
authors.lastname: Kanayama
mesh_terms: D000022:Abortion, Spontaneous / Q000378:metabolism*; D001826:Body Fluids / Q000378:metabolism*; D002584:Cervix Uteri / Q000378:metabolism*; D006063:Chorionic Gonadotropin / Q000032:analysis* / Q000378:metabolism*; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D006063:Chorionic Gonadotropin