title: High incidence of cytomegalovirus reactivation in adult recipients of an unrelated cord blood transplant.
abstract: This retrospective analysis of cytomegalovirus (CMV)-seropositive adult transplant recipients showed that CMV antigenemia occurred after transplantation in 10/10 (100%) recipients of unrelated cord blood, 17/39 (43%) recipients of a related matched donor graft, 16/23 (79%) recipients of an unrelated matched donor graft, and 8/12 (67%) recipients of a mismatched related donor graft. These results suggest that unrelated cord blood transplantation itself may be correlated with a high incidence of CMV reactivation.
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Takami
authors.forename: Kanako
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Hidesaku
authors.initials: H
authors.lastname: Asakura
authors.forename: Hirohito
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Okumura
authors.forename: Shinji
authors.initials: S
authors.lastname: Nakao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects*; D003587:Cytomegalovirus / Q000502:physiology*; D003586:Cytomegalovirus Infections / Q000276:immunology* / Q000601:surgery* / Q000821:virology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014775:Virus Activation