title: Skin ageing: a comparison between Chinese and European populations. A pilot study.
abstract: BACKGROUND
  Although limited data are available, it is commonly considered that Europeans and Asians have different skin ageing features.
  
  
  OBJECTIVE
  The present studies have been carried out to evaluate the influence of age and sun-exposure on the main clinical signs of Asian skin ageing.
  
  
  METHODS
  One hundred and sixty Chinese and 160 French age-matched women (age range: 20-60 years old) were clinically examined and scored by the same dermatologist. Facial wrinkles (crow's-feet, glabella and perioral wrinkles) and pigmented spots (on face and hands) were assessed in situ and standardized photographs of the face were taken. Lifelong sun-exposure was estimated from answers to a questionnaire. Comparisons were made between 10-year age groups.
  
  
  RESULTS
  Results show that, for each facial skin area, wrinkle onset is delayed by about 10 years in Chinese women as compared to French women. Facial wrinkling rate over the years is linear in French women and not linear in Chinese women who appear to experience a fast ageing process between age 40 and 50. Pigmented spot intensity is a much more important ageing sign in Chinese women (severe for 30% of women over 40) than in French women (severe for less than 8% of women, irrespective of age).
  
  
  CONCLUSIONS
  These first results underline that main skin ageing features (wrinkles, spots) progress differently in the Chinese and French women we have studied. They require to be confirmed on broad multicentre studies involving larger cohorts.
authors.affiliation: L'Oréal Recherche, Centre Charles Zviak, 90 rue du General Roguet, 92583 Clichy, France.
authors.forename: S
authors.initials: S
authors.lastname: Nouveau-Richard
authors.forename: Z
authors.initials: Z
authors.lastname: Yang
authors.forename: S
authors.initials: S
authors.lastname: Mac-Mary
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: P
authors.initials: P
authors.lastname: Bastien
authors.forename: I
authors.initials: I
authors.lastname: Tardy
authors.forename: C
authors.initials: C
authors.lastname: Bouillon
authors.forename: P
authors.initials: P
authors.lastname: Humbert
authors.forename: O
authors.initials: O
authors.lastname: de Lacharrière
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D004781:Environmental Exposure; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D010865:Pilot Projects; D015995:Prevalence; D015595:Skin Aging; D012880:Skin Pigmentation; D012907:Smoking / Q000208:ethnology; D013472:Sunlight; D044465:White People / Q000706:statistics & numerical data*