[Effects of silverionized drinking water on lipids metabolism in tail-suspended rats].
OBJECTIVE
To study the effect of silverionized drinking water on erythrocyte membrane fluidity, serum lipids and vascular endothelial cells in tail-suspended rats.


METHODS
Thirty male SD rats were randomly divided into ground control group (GC), simulated weightlessness control group (SC), simulated weightlessness and silverionized water drinking group (SS). Number of circulating endothelial cells (CEC), serum lipids and erythrocyte membranes fluidity was measured on the 21st day of tail suspension.


RESULTS
Levels of serum TC, TG, HDL-C, HDL-C/TC and erythrocyte membrane fluidity in SC rats were significantly lower than those in GC rats; LDL-C/HDL-C ratio and number of CEC in SC rats were markedly higher than those in GC rats. Levels of serum TC, LDL-C and LDL-C/HDL-C in SS rats were higher than those in SC rats; HDL-C/TC ratio and erythrocyte membrane fluidity in SS rats were lower than those in SC rats.


CONCLUSIONS
Drinking silverionized water has a negative effect on lipid metabolism in tail-suspended rats.
Zhu
De-bing
DB
Institute of Space Medico-Engineering, Beijing, China.
Huang
Ji-ming
JM
Li
Zhi-xia
ZX
Hong
Jian-wu
JW
Bai
Shu-min
SM
Chen
San-feng
SF
D000818:Animals; D008076:Cholesterol, HDL / Q000187:drug effects* / Q000378:metabolism; D008078:Cholesterol, LDL / Q000187:drug effects* / Q000378:metabolism; D042783:Endothelial Cells / Q000187:drug effects; D019417:Hindlimb Suspension; D008297:Male; D008560:Membrane Fluidity; D051381:Rats; D017207:Rats, Sprague-Dawley; D012834:Silver / Q000494:pharmacology*; D014280:Triglycerides / Q000378:metabolism; D014867:Water / Q000494:pharmacology*; D018474:Weightlessness Simulation
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D014867:Water; D012834:Silver