Nickel-catalyzed coupling of isocyanates with 1,3-iodoesters and halobenzenes: a novel method for the synthesis of imide and amide derivatives.
Substituted imide and amide derivatives were conveniently prepared from the reaction of isocyanates with o-iodobenzoates and haloarenes catalyzed by the NiBr2(dppe)/dppe/Zn system in moderate to good yields with excellent tolerance of functional groups.
Hsieh
Jen-Chieh
JC
Department of Chemistry, National Tsing Hua University, Hsinchu, 30013 Taiwan.
Cheng
Chien-Hong
CH