title: Antimicrobial screening of certain fused 1,2,4-triazine derivatives.
abstract: The synthesized fused 1,2,4-triazines were tested for their potential antimicrobial activity resulting from the literature data. Microbiological screening tests conducted in relation to 54 strains of Gram-positive and 52 strains of Gram-negative bacteria, 6 strains of yeast-like fungi and 3 strains of moulds showed that these compounds in examined concentrations 100 mg ml(-1) and 200 mg ml(-1) had no influence on the growth of microorganisms tested. The microbiological screening tests afforded to limit the possible biological spectrum of activity of tested compounds.
authors.affiliation: Department of Synthesis and Technology of Drugs, Skubiszewski Medical University of Lublin.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Sztanke
authors.forename: Anna
authors.initials: A
authors.lastname: Sidor-Wójtowicz
authors.forename: Janina
authors.initials: J
authors.lastname: Truchlińska
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Pasternak
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Sztanke
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D014227:Triazines / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D014227:Triazines