title: Reversal of hypogonadotropic hypogonadism with tamoxifen in a patient with hyperprolactinemia resistant to dopamine agonists.
abstract: OBJECTIVE
  To determine the response to tamoxifen in a woman with hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonist drugs.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Academic fertility center.
  
  
  METHODS
  A young woman with persistent amenorrhea, symptomatic hypogonadotropic hypogonadism, and hyperprolactinemia.
  
  
  METHODS
  Tamoxifen was administered in addition to bromocriptine.
  
  
  METHODS
  Measurements of follicle-stimulating hormone, estradiol, prolactin, and progesterone.
  
  
  RESULTS
  Recovery of gonadal-hypothalamic-pituitary axis.
  
  
  CONCLUSIONS
  Tamoxifen can revert the effects of chronic hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonists.
authors.affiliation: Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. jmlopez@med.puc.cl
authors.forename: José M
authors.initials: JM
authors.lastname: López
authors.forename: Eveline
authors.initials: E
authors.lastname: Oestreicher
mesh_terms: D000328:Adult; D018491:Dopamine Agonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000188:drug therapy*; D007006:Hypogonadism / Q000097:blood / Q000188:drug therapy*; D011388:Prolactin / Q000097:blood; D013629:Tamoxifen / Q000627:therapeutic use*
chemical_list: D018491:Dopamine Agonists; D013629:Tamoxifen; D011388:Prolactin