title: Genetic analysis of the TOR pathway in Aspergillus nidulans.
abstract: We identified five genes encoding components of the TOR signaling pathway within Aspergillus nidulans. Unlike the situation in Saccharomyces cerevisiae, there is only a single Tor kinase, as in plant and animal systems, and mutant phenotypes suggest that the TOR pathway plays only a minor role in regulating nitrogen metabolism.
authors.affiliation: The University of Liverpool, School of Biological Sciences, The Biosciences Building, Crown Street, Liverpool L69 7ZB, United Kingdom.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Fitzgibbon
authors.forename: Igor Y
authors.initials: IY
authors.lastname: Morozov
authors.forename: Meriel G
authors.initials: MG
authors.lastname: Jones
authors.forename: Mark X
authors.initials: MX
authors.lastname: Caddick
mesh_terms: D000595:Amino Acid Sequence; D000935:Antifungal Agents / Q000494:pharmacology; D001233:Aspergillus nidulans / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D025141:Drug Resistance, Fungal; D005656:Fungal Proteins / Q000235:genetics* / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D009584:Nitrogen / Q000378:metabolism; D010641:Phenotype; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D020123:Sirolimus / Q000494:pharmacology; D058570:TOR Serine-Threonine Kinases
chemical_list: D000935:Antifungal Agents; D005656:Fungal Proteins; D012333:RNA, Messenger; D011494:Protein Kinases; D058570:TOR Serine-Threonine Kinases; D009584:Nitrogen; D020123:Sirolimus