[Leptin concentration in pregnant women with hypertension and its correlation with body mass index].
Arterial hypertension is one of the reasons of high rate of mother and fetal mortality. The main aim of the study was to find the correlation between the leptin concentration, the BMI value and the risk of hypertension in pregnancy.


METHODS
the study was conducted in High Risk Pregnancy Department of the Medical University of Lodz in 2001-2003. The study group consists of 126 pregnant women with arterial hypertension. BMI, leptin concentration and arterial blood pressure were measured. The measurement was done every 4 weeks from 20 weeks of gestation, Leptin Elisa kit was used. The leptin measurement was done spectrophotometrically.


RESULTS
In group of obese pregnant women we found the correlation between BMI and high blood pressure if the high BMI was observed before pregnancy. Leptin concentration and the risk of hypertension was higher in the group of obese pregnant women.


CONCLUSIONS
In obese pregnant women the risk of HA was high and the high value of BMI before pregnancy is the risk factor of hypertension in pregnancy.
Estemberg
Dorota
D
Klinika Patologii Ciazy I Katedry Połoznictwa i Ginekologii Uniwersytetu Medycznego, Lodzi.
Kowalska-Koprek
Urszula
U
Kuś
Ewa
E
Estemberg
Paweł
P
Karowicz-Bilińska
Agata
A
D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology*; D020738:Leptin / Q000097:blood*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000503:physiopathology*
D020738:Leptin