Galaxy: a platform for interactive large-scale genome analysis.
Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.
Giardine
Belinda
B
Center for Comparative Genomics and Bioinformatics, Huck Institutes for Life Sciences, Penn State University, University Park, Pennsylvania 16802, USA.
Riemer
Cathy
C
Hardison
Ross C
RC
Burhans
Richard
R
Elnitski
Laura
L
Shah
Prachi
P
Zhang
Yi
Y
Blankenberg
Daniel
D
Albert
Istvan
I
Taylor
James
J
Miller
Webb
W
Kent
W James
WJ
Nekrutenko
Anton
A
D005075:Biological Evolution; D030541:Databases, Genetic; D016678:Genome; D020407:Internet; D011401:Promoter Regions, Genetic