title: [Molecular pathology of brain tumors].
abstract: Somatic genetic alterations can be used to differentiate primary from secundary glioblastomas. The molecular pathways involved in tumerogenesis have been described and we now have a better knowledge of tumor biology. Central Nervous System Tumors classification will probably include genetic changes in an early future with potential implications for therapy and patients prognostic.
authors.forename: Julián
authors.initials: J
authors.lastname: Sanz Esponera
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000145:classification / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D002453:Cell Cycle; D003937:Diagnosis, Differential; D005909:Glioblastoma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D006801:Humans; D009154:Mutation; D011379:Prognosis; D014944:World Health Organization