title: Anti-inflammatory activity of Lippia dulcis.
abstract: Lippia dulcis hexane and ethanol extracts were tested for its anti-inflammatory activity in several animal models. Hexane extract showed to be inactive, but the ethanol extract at doses of 400 mg/kg produced significant inhibition of carrageenan-induced paw oedema and reduced the weight of cotton pellet-induced granuloma, moreover, the topical application of 0.5 mg/ear of this extract inhibited the edema induced with TPA by 49.13%, an effect which is of less intensity than that produced by indomethacine at the same dose.
authors.affiliation: Depto Sistemas Biológicos, Universidad Autónoma Metropolitana-Xochimilco, A.P. 23-181, México D.F., Mexico. msperez@correo.xoc.uam.mx
authors.forename: S
authors.initials: S
authors.lastname: Pérez
authors.forename: M
authors.initials: M
authors.lastname: Meckes
authors.forename: C
authors.initials: C
authors.lastname: Pérez
authors.forename: A
authors.initials: A
authors.lastname: Susunaga
authors.forename: M A
authors.initials: MA
authors.lastname: Zavala
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D006801:Humans; D032411:Lippia; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts