title: Sarcoidosis mimicking recurrent endometrial cancer.
abstract: BACKGROUND
  Sarcoidosis is a multisystem disease and can be confused with benign or malignant tumors. In patients with recurrent gynecologic cancer, liver and intrathoracic lesions should undergo a biopsy to rule in metastatic malignancy, as clinical findings and CAT scan results may represent other disease processes.
  
  
  METHODS
  A 67 year old woman had a total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic and periaortic lymphadenectomy, and peritoneal cytology in 2001 for Stage I B grade 1 adenocarcinoma of the endometrium. She developed a vaginal recurrence in 2005. A CT scan of lungs, abdomen, and pelvis revealed extensive mediastinal adenopathy and multiple space occupying hepatic lesions worrisome for metastatic disease. A needle biopsy of the largest liver lesion revealed sarcoidosis.
  
  
  CONCLUSIONS
  Sarcoid lesions may mimic metastatic disease in patients with malignancy, potentially leading to delayed and/or inappropriate therapy.
authors.affiliation: Department of Obstetrics, New Hanover Regional Medical Center, Coastal Area Health Education Center, 2131 South 17th Street, Wilmington, NC 28402-9025, USA. john.powell@coastalahec.org
authors.forename: John L
authors.initials: JL
authors.lastname: Powell
authors.forename: Erica S
authors.initials: ES
authors.lastname: Cunill
authors.forename: Walter H
authors.initials: WH
authors.lastname: Gajewski
authors.forename: Debra B
authors.initials: DB
authors.lastname: Novotny
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology; D012507:Sarcoidosis / Q000175:diagnosis* / Q000473:pathology