Electroorganic synthesis of catecholthioethers.
[reaction: see text] It is demonstrated that o-quinones, generated by the electrochemically driven oxidation of the catechols (1a-d) at physiological pH, are rapidly scavenged by 2-mercaptobenzoxazole (3) to give related catecholthioethers (4a-d) via an EC electrochemical mechanism pathway. The electrochemical syntheses of 4a-d have been successfully performed in one-pot in ambient conditions and in an undivided cell using an environmentally friendly method with high atom economy.
Nematollahi
Davood
D
Department of Chemistry, Faculty of Science, University of Bu-Ali-Sina, Hamadan 65174, Iran. nemat@basu.ac.ir
Tammari
Esmail
E
D002396:Catechols / Q000138:chemical synthesis*; D004563:Electrochemistry; D013440:Sulfides / Q000138:chemical synthesis*
D002396:Catechols; D013440:Sulfides