title: Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe.
abstract: The spread of the plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 was detected in Acinetobacter sp. clinical isolates from southern Europe, the Balkans, and central Turkey. It may contribute significantly to the emergence of carbapenem resistance in Acinetobacter spp., at least in this part of the world.
authors.affiliation: Service de Bactériologie-Virologie, Hôpital de Bicêtre, Le-Kremlin-Bicêtre, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Marqué
authors.forename: Laurent
authors.initials: L
authors.lastname: Poirel
authors.forename: Claire
authors.initials: C
authors.lastname: Héritier
authors.forename: Sylvain
authors.initials: S
authors.lastname: Brisse
authors.forename: Maria Dolores
authors.initials: MD
authors.lastname: Blasco
authors.forename: Roxana
authors.initials: R
authors.lastname: Filip
authors.forename: Gabriela
authors.initials: G
authors.lastname: Coman
authors.forename: Thierry
authors.initials: T
authors.lastname: Naas
authors.forename: Patrice
authors.initials: P
authors.lastname: Nordmann
mesh_terms: D000150:Acinetobacter / Q000187:drug effects* / Q000201:enzymology*; D000151:Acinetobacter Infections / Q000453:epidemiology / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015780:Carbapenems / Q000378:metabolism* / Q000494:pharmacology; D005060:Europe / Q000453:epidemiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D001618:beta-Lactamases; C108449:oxacillinase