[Clinical analysis of Peutz-Jeghers syndrome:a report of 6 cases].
OBJECTIVE
To investigate the diagnostic methods and reasonable treatment of Peutz-Jeghers syndrome (PJS).


METHODS
Clinical data of six patients with PJS were reviewed.


RESULTS
Repeated abdominal pain, intussusception and intestinal polyp with bleeding were main manifestations. Four patients father,three patients grandfather and one patients mother were diagnosed with PJS. Three patients had family history of cancer. Case 4 and case 5 underwent laparotomy for many times because of intussusceptions caused by polyps or recurrent abdominal pain. Case 1 and case 4 had polyps synchronous with adenoma, and case 2 had polyp with gastric cancer. Main treatment included polyp resection and partial small intestinal and colon resection.


CONCLUSIONS
Patients with PJS have family history of cancer and a high incidence of polyp recurrence of small intestine. Surgical intervention is the first choice regimen. Surveillance should be emphasized on gastrointestinal tract and other potential malignant organs in PJS patients.
Dong
Ke
K
Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. dongke1134@hotmail.com
Li
Bo
B
Li
Ben-hai
BH
Guan
Quan-lin
QL
Huo
Yong-zhong
YZ
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D010375:Pedigree; D010580:Peutz-Jeghers Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery*