Ulcerative keratitis in mycosis fungoides.
OBJECTIVE
To present a case of ulcerative keratitis and impending corneal perforation in a patient with mycosis fungoides (cutaneous T-cell lymphoma) that developed eyelid involvement.


METHODS
Case report analysis. Cultures and biopsies of the right cornea, conjunctiva, and eyelids were obtained. Biopsy tissue was examined with histologic and immunohistologic stains.


RESULTS
This patient with mycosis fungoides involving the eyelids developed corneal exposure and bacterial keratitis with impending corneal perforation. Lamellar keratoplasty and permanent tarsorrhaphy were performed to protect the globe from perforation.


CONCLUSIONS
Mycosis fungoides involving the eyelids is capable of causing severe ocular tissue injury without direct infiltration of the malignant lymphocytes. Preventative medical and surgical measures must be taken to protect the globe.
Goldberg
Damien F
DF
Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA. Damien_Goldberg@yahoo.com
Negvesky
Gerald J
GJ
Butrus
Salim I
SI
Goodglick
Todd A
TA
D000890:Anti-Infective Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D016039:Corneal Transplantation; D003320:Corneal Ulcer / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005142:Eyelid Neoplasms / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications*; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012878:Skin Neoplasms / Q000150:complications*
D000890:Anti-Infective Agents