[Modification of mutation processes in culture of human lymphocytes with tea extracts].
Antimutagenic activity of the extracts of tea leaves from different stages of technological processing has been investigated. Culture of human lymphocyte cells was used as a test-object. Mutations have been induced with gamma-rays, N-methyl-N1-nitro-N-nitrosoguanidine (MNNG) and benz-[a]-pyren. All the extracts showed ability to decrease the frequency of chromosome aberrations with high effectiveness. The effectiveness of green tea leaf extracts was higher in comparison with the effectiveness of the extracts from the late stages of processing.
Guseĭnov
M B
MB
Agabeĭli
R A
RA
Alekperov
U K
UK
D016587:Antimutagenic Agents / Q000494:pharmacology*; D001564:Benzo(a)pyrene / Q000633:toxicity; D028241:Camellia sinensis / Q000737:chemistry*; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000139:chemically induced / Q000187:drug effects* / Q000528:radiation effects; D005720:Gamma Rays; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000528:radiation effects; D009153:Mutagens / Q000633:toxicity; D009154:Mutation; D009604:Nitrosoguanidines / Q000633:toxicity; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry
D016587:Antimutagenic Agents; D009153:Mutagens; D009604:Nitrosoguanidines; D010936:Plant Extracts; D001564:Benzo(a)pyrene