Enhanced metabolic stability and protein-binding properties of artificial alpha helices derived from a hydrogen-bond surrogate: application to Bcl-xL.
Wang
Deyun
D
Department of Chemistry, New York University, New York, NY 10003, USA.
Liao
Wei
W
Arora
Paramjit S
PS
D000595:Amino Acid Sequence; D032701:Biomimetics; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry; D011485:Protein Binding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D050998:bcl-2 Homologous Antagonist-Killer Protein / Q000737:chemistry* / Q000378:metabolism*; D051020:bcl-X Protein / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*
D010455:Peptides; D050998:bcl-2 Homologous Antagonist-Killer Protein; D051020:bcl-X Protein