title: Prenatal diagnosis and management for a large fetal cardiac tumor complicated with hydrops fetalis.
abstract: Fetal cardiac tumor is a rare disease, and its prognosis varies in relation to the complications such as arrhythmia and out-flow obstruction. Hydrops fetalis is one of severe complications that result in an unfavorable outcome. A case is presented herein of a large fetal cardiac tumor diagnosed at 28 weeks gestation. At 30 weeks gestation, the fetus complicated with hydrops fetalis because of impaired cardiac function. Increased peak systolic velocity in the ascending aorta and marked reversed flow in the ductus venosus were observed. Oral digoxin therapy was administered to the mother as a cardiotonic agent and the hydropic condition was immediately diminished. After normal delivery, the cardiac tumor gradually decreased in size and the infant developed normally, but required an antiarrhythmic drug. The case indicates that the in utero digoxin therapy could be a choice for hydrops fetalis caused by cardiac tumor.
authors.affiliation: Perinatal Care Center, Yamaguchi University Hospital, Ube, Japan. miyabi@yamaguchi-u.ac.jp
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nakata
authors.forename: Motoki
authors.initials: M
authors.lastname: Fujiwara
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sumie
authors.forename: Keiko
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Ichiro
authors.initials: I
authors.lastname: Miwa
authors.forename: Emiko
authors.initials: E
authors.lastname: Kusaka
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Sase
authors.forename: Norihiro
authors.initials: N
authors.lastname: Sugino
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004077:Digoxin / Q000627:therapeutic use*; D005260:Female; D005333:Fetus; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D007231:Infant, Newborn; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin