title: Difference in cytokine production and cell activation between adenoidal lymphocytes and peripheral blood lymphocytes of children with otitis media.
abstract: We evaluated the immunological potential of adenoidal lymphocytes from children with recurrent otitis media. Interleukin-4 release and CD69 expression were lower in adenoidal lymphocytes than in peripheral blood lymphocytes (PBL). Our results suggest that there may be a difference between the immunological potential of adenoidal lymphocytes and that of PBL in children with otitis.
authors.affiliation: Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8543, Japan. harimaya@sapmed.ac.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Harimaya
authors.forename: Jussi
authors.initials: J
authors.lastname: Tarkkanen
authors.forename: Petri
authors.initials: P
authors.lastname: Mattila
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Fujii
authors.forename: Jukka
authors.initials: J
authors.lastname: Ylikoski
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Himi
mesh_terms: D000234:Adenoids / Q000166:cytology / Q000276:immunology*; D015703:Antigens, CD / Q000378:metabolism; D000945:Antigens, Differentiation, T-Lymphocyte / Q000378:metabolism; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D016207:Cytokines / Q000378:metabolism*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D037181:Lectins, C-Type; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D010033:Otitis Media / Q000276:immunology*; D012008:Recurrence; D000099192:CD69 Antigens
chemical_list: D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D016207:Cytokines; D037181:Lectins, C-Type; D000099192:CD69 Antigens