title: [Efficacy of tracrolimus 0.1% ointment in prurigo].
abstract: BACKGROUND
  Potent topical corticosteroids are used the intense pruritus in prurigo diseases. Their long-term application leads to local side effects such as atrophy and telangiectasia.
  
  
  METHODS
  We treated 6 women (average age 64 years) with chronic prurigo with tacrolimus 0.1 % ointment (Protopic) to evaluate its efficacy in this clinical setting. Tacrolimus 0.1% ointment was applied twice a day for 4 weeks.
  
  
  RESULTS
  After one week, both clinical improvement and reduced pruritus were observed in all patients.
  
  
  CONCLUSIONS
  Tacrolimus 0.1% ointment represents a therapeutic option for the treatment of prurigo.
authors.affiliation: Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin.
authors.forename: Hae-Hyuk
authors.initials: HH
authors.lastname: Lee
authors.forename: Wolfram
authors.initials: W
authors.lastname: Sterry
authors.forename: Margitta
authors.initials: M
authors.lastname: Worm
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D009824:Ointments; D011536:Prurigo / Q000188:drug therapy*; D016559:Tacrolimus / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus