Use of proteomic patterns as a novel screening tool in pre-eclampsia.
This pilot study aimed to use Ciphergen ProteinChip technology to determine differences in protein profiles in plasma, taken at 26 weeks, from women at risk of developing pre-eclampsia. Five proteins were found to be significantly up-regulated in samples from women who subsequently developed pre-eclampsia compared with women who remained normotensive.
Myers
Jenny
J
Maternal and Fetal Health Research Centre, St Mary's Hospital, University of Manchester, Manchester, UK. jenny.myers@man.ac.uk
Macleod
Maureen
M
Reed
B
B
Harris
N
N
Mires
G
G
Baker
P
P
D001798:Blood Proteins / Q000032:analysis*; D003933:Diagnosis; D005260:Female; D005865:Gestational Age; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008403:Mass Screening / Q000379:methods*; D011225:Pre-Eclampsia; D011247:Pregnancy; D040901:Proteomics; D015203:Reproducibility of Results
D001798:Blood Proteins