Recurrent severe hypercalcemia caused by bone marrow sarcoidosis.
A 71-year-old woman with recurrent severe hypercalcemia was found to have multiple noncaseating granulomas in the bone marrow with low parathyroid hormone levels and high levels of [1,25 dihydroxycholecalciferol] that later decreased to normal levels with the normalization of calcium levels. No organ involvement other than of the bone marrow was detected, and the angiotensin-converting enzyme level was elevated. The diagnosis of bone marrow sarcoidosis is suggested.
Saliba
Walid R
WR
Department of Medicine C, Hae'meK Medical Center, Technion-Israel Institute of Technology, Faculty of Medicine, Afula, Israel. salibuss@yahoo.com
Elias
Mazen S
MS
D000368:Aged; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology* / Q000473:pathology*; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology*