Ultra-structure of the oral cavity epithelial cells in white rat after experimental application of Naran S preparation.
The effectiveness of the natural drug--Naran S was studied in the therapy of the topical inflammation of the oral cavity mucous membrane. The experiment was conducted on male Wistar rats that were subjected to induction of inflammatory condition by injecting Freund adjuvant and rinsing oral cavity with the infusion of the drug for the period of 28 days. The analysis of the ultra structure of the epithelium cells was conducted with the use of transmission electron microscope. It was observed that under the influence of the drug, the epithelium undergoes renewal, the cells are joined with thick desmosomes, the nuclei have the proper areolas and the mitochondrium matrix is not oedematic.
Wołoszyn
Iwona
I
Department of Inorganic Chemistry, Skubiszewski Medical University of Lublin.
Matysik
Grazyna
G
Lańcut
Mirosław
M
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D004195:Disease Models, Animal; D005419:Flavonoids / Q000494:pharmacology*; D005620:Freund's Adjuvant; D005881:Gingiva / Q000187:drug effects* / Q000473:pathology; D039823:Iridoids / Q000494:pharmacology*; D008297:Male; D009061:Mouth Mucosa / Q000187:drug effects* / Q000473:pathology; D009067:Mouthwashes / Q000494:pharmacology*; D010636:Phenols / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012038:Regeneration / Q000187:drug effects; D013634:Tannins / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D005419:Flavonoids; D039823:Iridoids; D009067:Mouthwashes; C504357:Naran S; D010636:Phenols; D010936:Plant Extracts; D013634:Tannins; D005620:Freund's Adjuvant