[Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin].
OBJECTIVE
To observe the effect on infantile allergic cough with Minkeqing oral liquid (Minkeqing) and to study its cell molecular biologic mechanism.


METHODS
The rat model was induced by inhalating ovalbumin; then the effects of Minkeqing on IL-6, IL-8, ET-1, TX-B2 in the blood and the bronchoalveolar lavage fluid (BALF) of the animal model were observed.


RESULTS
Minkeqing could reduce the levels of IL-6,IL-8,ET-1,Tx-B2 in the blood and BALF of the animal model.


CONCLUSIONS
Minkeqing has the significant function of inhibiting the release of inflammatory mediums.
Zhu
Shan
S
Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. zhsh@hactcm.edu.cn
Zhai
Wen-Sheng
WS
Li
Xiang-Yun
XY
D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D003371:Cough / Q000097:blood / Q000139:chemically induced / Q000378:metabolism*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D019332:Endothelin-1 / Q000097:blood / Q000378:metabolism; D006967:Hypersensitivity / Q000097:blood / Q000378:metabolism; D015850:Interleukin-6 / Q000097:blood / Q000378:metabolism; D016209:Interleukin-8 / Q000097:blood / Q000378:metabolism; D008297:Male; D010047:Ovalbumin; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013929:Thromboxane B2 / Q000097:blood / Q000378:metabolism
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D019332:Endothelin-1; D015850:Interleukin-6; D016209:Interleukin-8; D013929:Thromboxane B2; D010047:Ovalbumin