Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC.
The present work describes the isolation of camptothecin and 9-methoxycamptothecin from the aerial parts of Nothapodytes foetida by semipreparative high-performance liquid chromatography because the separation of compounds by conventional procedures is tedious and cumbersome. The purity of the isolates is determined by physicochemical data and liquid chromatography-mass spectrometry.
Puri
S C
SC
Regional Research Laboratory (CSIR), Jammu-180 001, India.
Handa
G
G
Bhat
B A
BA
Gupta
V K
VK
Amna
T
T
Verma
N
N
Anand
R
R
Dhar
K L
KL
Qazi
G N
GN
D002166:Camptothecin / Q000031:analogs & derivatives* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D002853:Chromatography, Liquid / Q000379:methods; D019684:Magnoliopsida / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods
C025724:9-methoxycamptothecin; D002166:Camptothecin