Gastric mucinous adenocarcinoma with cutaneous metastases in a dog: diagnosis by fine-needle aspiration cytology.
A 12-year-old, intact, male mixed-breed dog was presented with anorexia, vomiting and multiple cutaneous nodules on its neck, trunk and hindlimbs. Fine-needle aspiration cytology of the nodules was characterised by a pleomorphic population of cells arranged singly or in small cohesive clusters, embedded in an amorphous mucinous material stained positive by periodic acid-Schiff (PAS). Acinar structures were occasionally found. Cells appeared either small with scant basophilic cytoplasm or large with a histiocytic appearance. Large cells had cytoplasm filled with a PAS-positive granular material. A presumptive diagnosis of cutaneous metastases of a mucinous adenocarcinoma was made. A primary, gastric, signet-ring mucinous adenocarcinoma was confirmed at postmortem examination and by histopathology. To the authors' knowledge, this is the first report of a gastric mucinous adenocarcinoma with cutaneous disseminated metastases in a dog.
Dell'Orco
M
M
Dipartimento di Patologia Animale Igiene e Sanità Pubblica Veterinaria, Sezione di Anatomia Patologica e Patologia Aviare, Università di Milano, via Celoria, Milan, Italy.
Bertazzolo
W
W
Vergine
M
M
Ferla
M
M
Pozzo
S
S
Rondena
M
M
Roccabianca
P
P
D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D044963:Biopsy, Fine-Needle / Q000379:methods / Q000662:veterinary; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D008297:Male; D012878:Skin Neoplasms / Q000556:secondary / Q000662:veterinary*; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*