title: Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
abstract: A 67-year-old man, who had widespread and well-defined erythematous violaceous hyperkeratotic plaques on his skin, was diagnosed with borderline tuberculoid leprosy. The patient began treatment with clofazimine, rifampicin, and dapsone, but 15 days afterwards he complained of acral edema with godet sign. Magnetic resonance imaging was done, and the case was interpreted as remitting seronegative symmetrical synovitis with pitting edema. About 8 mg/day of methylprednisolone were started with excellent response.
authors.affiliation: Department of Rheumatology, Hospital Bernardino Rivadavia, Borges 2165, 6th-A floor, 1425 Buenos Aires, Argentina. ahelling@intramed.net.ar
authors.forename: Claudia Andrea
authors.initials: CA
authors.lastname: Helling
authors.forename: Ana
authors.initials: A
authors.lastname: Locursio
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Manzur
authors.forename: Maria Leticia
authors.initials: ML
authors.lastname: Sormani de Fonseca
mesh_terms: D000368:Aged; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004487:Edema / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005528:Foot / Q000473:pathology; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D007918:Leprosy / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D013585:Synovitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D007917:Leprostatic Agents; D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin; D008775:Methylprednisolone