[Evaluation of fetomaternal hemorrhage in postpartum patients with indication for administration of anti-D immunoglobulin].
This study evaluated fetomaternal hemorrhage (FMH) in 343 postpartum patients who required prophylaxis of Rh alloimmunization with anti-D immunoglobulin. The rosette test was applied to screen for patients needing quantitative determination of fetal blood transferred from the maternal circulation, which was then measured by the Kleihauer-Betke test (K-B). The rosette test was positive in 22 cases (6.4%). In five of these cases, K-B did not show fetomaternal hemorrhage (a 1.45% false-positive rate for the rosette test), and in one case the test was inconclusive. There were 8 cases with FMH < 10 ml (2.3%), 6 cases with FMH from 10 to 30 ml (1.7%), and two cases with FMH > 30 ml (0.58%), requiring a supplementary dose of anti-D. The study concludes that following the rosette test, additional evaluation of FMH using a quantitative test was unnecessary in 93.6% of the cases.
Baiochi
Eduardo
E
Departamento de Obstetrícia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil. baiochi.toco@epm.br
Camano
Luiz
L
Bordin
José Orlando
JO
D000328:Adult; D001810:Blood Volume; D005260:Female; D005331:Fetomaternal Transfusion / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D049590:Postpartum Period; D011247:Pregnancy; D012203:Rh Isoimmunization / Q000517:prevention & control*; D018029:Rho(D) Immune Globulin / Q000008:administration & dosage* / Q000627:therapeutic use; D014218:Triage / Q000191:economics / Q000379:methods*
D018029:Rho(D) Immune Globulin