Does dietary salt increase the risk for progression of kidney disease?
Due to the inconsistent observations and suboptimal quality of the study designs, there is insufficient clinical evidence to suggest that increased salt intake may adversely modify the rate of progression of kidney disease. However, there is experimental evidence to suggest a link between increased salt exposure and kidney tissue injury. Further clinical trials are needed to evaluate the relationship between dietary salt and risk for progression of chronic kidney disease.
Mishra
Shiraz I
SI
Division of Nephrology, University of Maryland School of Medicine, 22 S. Greene Street, Room N3W143, Baltimore, MD 21201, USA.
Jones-Burton
Charlotte
C
Fink
Jeffrey C
JC
Brown
Jeanine
J
Bakris
George L
GL
Weir
Matthew R
MR
D000818:Animals; D002908:Chronic Disease; D018450:Disease Progression; D006801:Humans; D007674:Kidney Diseases / Q000378:metabolism*; D017673:Sodium Chloride, Dietary / Q000009:adverse effects* / Q000378:metabolism
D017673:Sodium Chloride, Dietary