title: The use of fluor-hydroxy pulse peel in actinic porokeratosis.
abstract: BACKGROUND
  The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions.
  
  
  OBJECTIVE
  The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis.
  
  
  METHODS
  A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses.
  
  
  RESULTS
  Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia.
  
  
  CONCLUSIONS
  The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.
authors.affiliation: Department of Dermatologym Cosmiatry Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil. solangeteixeira@clinderm.com.br
authors.forename: Solange P
authors.initials: SP
authors.lastname: Teixeira
authors.forename: Maurício M
authors.initials: MM
authors.lastname: de Nascimento
authors.forename: Ediléia
authors.initials: E
authors.lastname: Bagatin
authors.forename: Karime M
authors.initials: KM
authors.lastname: Hassun
authors.forename: Sérgio
authors.initials: S
authors.lastname: Talarico
authors.forename: Nilceo
authors.initials: N
authors.lastname: Michalany
mesh_terms: D001706:Biopsy; D002615:Chemexfoliation / Q000379:methods*; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006016:Glycolates / Q000627:therapeutic use*; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008875:Middle Aged; D017499:Porokeratosis / Q000188:drug therapy* / Q000209:etiology; D012867:Skin / Q000473:pathology; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D006016:Glycolates; D007641:Keratolytic Agents; C031149:glycolic acid; D005472:Fluorouracil