title: Efficient and stereodivergent synthesis of deoxyimino sugars.
abstract: Both cis- and trans-2-substituted-1,2,3,6-tetrahydro-pyridin-3-ols have been prepared via an aldol condensation-ring-closing metathesis sequence. A stereodivergent synthesis of optionally functionalized deoxyimino sugars was achieved via asymmetric dihydroxylation or epoxidation/nucleophilic substitution of these tetrahydropyridines.
authors.affiliation: Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi 621, Taiwan, ROC. chebch@ccu.edu.tw
authors.forename: Bor-Cherng
authors.initials: BC
authors.lastname: Hong
authors.forename: Zhong-Yi
authors.initials: ZY
authors.lastname: Chen
authors.forename: Arumugam
authors.initials: A
authors.lastname: Nagarajan
authors.forename: Rudresha
authors.initials: R
authors.lastname: Kottani
authors.forename: Vishal
authors.initials: V
authors.lastname: Chavan
authors.forename: Wei-Hung
authors.initials: WH
authors.lastname: Chen
authors.forename: Yea-Fen
authors.initials: YF
authors.lastname: Jiang
authors.forename: Shuo-Cang
authors.initials: SC
authors.lastname: Zhang
authors.forename: Ju-Hsiou
authors.initials: JH
authors.lastname: Liao
authors.forename: Sepehr
authors.initials: S
authors.lastname: Sarshar
mesh_terms: D018360:Crystallography, X-Ray; D003837:Deoxy Sugars / Q000138:chemical synthesis* / Q000737:chemistry; D050111:Imino Sugars / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003837:Deoxy Sugars; D050111:Imino Sugars