Relationship of in vivo medial temporal lobe magnetic resonance spectroscopy to documented combat exposure in veterans with chronic posttraumatic stress disorder.
Veterans diagnosed with combat-related posttraumatic stress disorder (PTSD) and comparison subjects underwent single voxel proton magnetic resonance spectroscopy (1H-MRS) of the medial temporal lobe (MTL). PTSD subjects were divided into combat and non-combat groups based on military records. Combat PTSD subjects did not have lower MTL levels of N-acetylaspartate compared with non-combat PTSD subjects.
Kimbrell
Tim
T
Mental Health Service, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA. TIMOTHY.KIMBRELL@VA.MED.GOV
Leulf
Claire
C
Cardwell
David
D
Komoroski
Richard A
RA
Freeman
Thomas W
TW
D001521:Behavior Therapy; D002908:Chronic Disease; D004282:Documentation; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D013313:Stress Disorders, Post-Traumatic / Q000378:metabolism* / Q000523:psychology* / Q000534:rehabilitation; D013702:Temporal Lobe / Q000378:metabolism*; D014728:Veterans / Q000523:psychology*; D047829:Vietnam Conflict