title: Coexistence of pemphigus vulgaris and bullous pemphigoid in the upper aerodigestive tract.
abstract: Pemphigus vulgaris and bullous pemphigoid are autoimmune blistering diseases of the skin and the mucosa characterized by circulating autoantibodies. Coexistence of these lesions is extremely uncommon. We report herein a case of both pemphigus vulgaris and bullous pemphigoid which occurred in the upper aerodigestive tract. The diagnosis was made based on the circulating autoantibodies and direct immunofluorescent studies. The literature on this subject is reviewed.
authors.affiliation: Department of Otolaryngology, Doctorial Program in Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan. ktabuchi@md.tsukuba.ac.jp
authors.forename: Keiji
authors.initials: K
authors.lastname: Tabuchi
authors.forename: Masatake
authors.initials: M
authors.lastname: Nomura
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Murashita
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujisawa
authors.forename: Shigeki
authors.initials: S
authors.lastname: Tsuji
authors.forename: Hideki
authors.initials: H
authors.lastname: Okubo
authors.forename: Akira
authors.initials: A
authors.lastname: Hara
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D051184:Desmoglein 3 / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D004947:Esophagus; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007830:Larynx; D008297:Male; D010391:Pemphigoid, Bullous / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D010392:Pemphigus / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D010614:Pharynx
chemical_list: D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D051184:Desmoglein 3; D007074:Immunoglobulin G