title: Structural biology. Adaptation of SARS coronavirus to humans.
authors.affiliation: University of Colorado Health Sciences Center, Mail Stop 8333, Post Office Box 6211, Aurora, CO 80045, USA. kathryn.holmes@uchsc.edu
authors.forename: Kathryn V
authors.initials: KV
authors.lastname: Holmes
mesh_terms: D000222:Adaptation, Physiological; D019943:Amino Acid Substitution; D000085962:Angiotensin-Converting Enzyme 2; D000818:Animals; D001665:Binding Sites; D002268:Carboxypeptidases / Q000737:chemistry* / Q000378:metabolism; D004196:Disease Outbreaks; D005814:Genes, Viral; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008562:Membrane Glycoproteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D007703:Peptidyl-Dipeptidase A; D017434:Protein Structure, Tertiary; D012367:RNA, Viral / Q000235:genetics; D011991:Receptors, Virus / Q000737:chemistry* / Q000378:metabolism; D011995:Recombination, Genetic; D045473:Severe acute respiratory syndrome-related coronavirus / Q000737:chemistry* / Q000235:genetics* / Q000502:physiology; D045169:Severe Acute Respiratory Syndrome / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology*; D013045:Species Specificity; D064370:Spike Glycoprotein, Coronavirus; D014759:Viral Envelope Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014765:Viral Vaccines; D014779:Virus Replication; D045949:Viverridae / Q000821:virology
chemical_list: D008562:Membrane Glycoproteins; D012367:RNA, Viral; D011991:Receptors, Virus; D064370:Spike Glycoprotein, Coronavirus; D014759:Viral Envelope Proteins; D014765:Viral Vaccines; C578557:spike glycoprotein, SARS-CoV; D002268:Carboxypeptidases; D007703:Peptidyl-Dipeptidase A; C000705307:ACE2 protein, human; D000085962:Angiotensin-Converting Enzyme 2