title: Post-LASIK corneal flap displacement following penetrating keratoplasty for bullous keratopathy.
abstract: OBJECTIVE
  To report 3 patients who experienced late flap dislocation after laser in situ keratomileusis (LASIK) in eyes that had undergone prior penetrating keratoplasty (PKP) for bullous keratopathy.
  
  
  METHODS
  Retrospective chart review of 2 referral corneal and refractive surgery practices, case reports, and literature review.
  
  
  RESULTS
  Three patients (mean age 58.3 years, 2 male, 1 female), all status post-corneal transplant for bullous keratopathy, had residual myopic astigmatism and underwent LASIK for correction of their significant anisometropia. Flap dislocation occurred at a mean of 7 days (range 3 to 14 days) following the LASIK procedure. All patients had peripheral corneal edema in their recipient bed. All 3 patients required an additional surgical procedure for visual rehabilitation.
  
  
  CONCLUSIONS
  Flap displacement may occur following LASIK in patients who have undergone PKP for bullous keratopathy. The endothelial pump function, which is vital to maintaining flap adherence, may be compromised in these patients. We suggest that patients with a history of PKP and endothelial compromise who undergo LASIK wear protective shields for a longer than normal period and be followed closely to reduce the risk of flap slippage.
authors.affiliation: Ophthalmic Consultants of Long Island, Rockville Centre, New York, NY 11570, USA.
authors.forename: Renée
authors.initials: R
authors.lastname: Solomon
authors.forename: Eric D
authors.initials: ED
authors.lastname: Donnenfeld
authors.forename: Henry D
authors.initials: HD
authors.lastname: Perry
authors.forename: Verinder S
authors.initials: VS
authors.lastname: Nirankari
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D015858:Anisometropia / Q000209:etiology / Q000601:surgery; D001251:Astigmatism / Q000209:etiology / Q000601:surgery; D003316:Corneal Diseases / Q000601:surgery*; D003319:Corneal Stroma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000209:etiology / Q000601:surgery; D011183:Postoperative Complications; D012189:Retrospective Studies; D013524:Surgical Flaps; D013529:Surgical Wound Dehiscence / Q000209:etiology* / Q000601:surgery