ANCA-associated vasculitis as paraneoplastic syndrome with colon cancer: a case report.
Coexistence of a vasculitis and a neoplastic disease is rare and the pathogenesis is unknown. Most of these associations refer to leukocytoclastic or poliarteritis nodosa (PAN)-type vasculitis and hematological malignancies. There are few reports of vasculitis in patients with solid tumours and there are also few reports of paraneoplastic ANCA-associated vasculitis. We report a case of p-ANCA-positive vasculitis with peripheral nerve involvement associated with a colon cancer. Vasculitis resolved after corticoid treatment and surgical removal of the tumour.
Diez-Porres
L
L
Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain. jjrios@movistar.com
Rios-Blanco
J J
JJ
Robles-Marhuenda
A
A
Gutiérrez-Molina
M
M
Gil-Aguado
A
A
Vázquez-Rodríguez
J J
JJ
D000230:Adenocarcinoma / Q000097:blood / Q000150:complications*; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D003110:Colonic Neoplasms / Q000097:blood / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000209:etiology*; D014657:Vasculitis / Q000097:blood / Q000209:etiology*
D019268:Antibodies, Antineutrophil Cytoplasmic