title: [Effects of silverionized drinking water on lipids metabolism in tail-suspended rats].
abstract: OBJECTIVE
  To study the effect of silverionized drinking water on erythrocyte membrane fluidity, serum lipids and vascular endothelial cells in tail-suspended rats.
  
  
  METHODS
  Thirty male SD rats were randomly divided into ground control group (GC), simulated weightlessness control group (SC), simulated weightlessness and silverionized water drinking group (SS). Number of circulating endothelial cells (CEC), serum lipids and erythrocyte membranes fluidity was measured on the 21st day of tail suspension.
  
  
  RESULTS
  Levels of serum TC, TG, HDL-C, HDL-C/TC and erythrocyte membrane fluidity in SC rats were significantly lower than those in GC rats; LDL-C/HDL-C ratio and number of CEC in SC rats were markedly higher than those in GC rats. Levels of serum TC, LDL-C and LDL-C/HDL-C in SS rats were higher than those in SC rats; HDL-C/TC ratio and erythrocyte membrane fluidity in SS rats were lower than those in SC rats.
  
  
  CONCLUSIONS
  Drinking silverionized water has a negative effect on lipid metabolism in tail-suspended rats.
authors.affiliation: Institute of Space Medico-Engineering, Beijing, China.
authors.forename: De-bing
authors.initials: DB
authors.lastname: Zhu
authors.forename: Ji-ming
authors.initials: JM
authors.lastname: Huang
authors.forename: Zhi-xia
authors.initials: ZX
authors.lastname: Li
authors.forename: Jian-wu
authors.initials: JW
authors.lastname: Hong
authors.forename: Shu-min
authors.initials: SM
authors.lastname: Bai
authors.forename: San-feng
authors.initials: SF
authors.lastname: Chen
mesh_terms: D000818:Animals; D008076:Cholesterol, HDL / Q000187:drug effects* / Q000378:metabolism; D008078:Cholesterol, LDL / Q000187:drug effects* / Q000378:metabolism; D042783:Endothelial Cells / Q000187:drug effects; D019417:Hindlimb Suspension; D008297:Male; D008560:Membrane Fluidity; D051381:Rats; D017207:Rats, Sprague-Dawley; D012834:Silver / Q000494:pharmacology*; D014280:Triglycerides / Q000378:metabolism; D014867:Water / Q000494:pharmacology*; D018474:Weightlessness Simulation
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D014867:Water; D012834:Silver