title: Usefulness of the TIMI Risk Index in predicting short- and long-term mortality in patients with acute coronary syndromes.
abstract: In a cohort of 710 patients with acute coronary syndromes (ACSs), we demonstrated that the Thrombolysis In Myocardial Infarction Risk Index--a predictor of 30-day mortality in clinical trial patients with ST-elevation myocardial infarction (STEMI)--is a strong predictor of short- and long-term mortality with good discrimination ability (c statistics 0.77 to 0.79) among all subtypes of ACSs (STEMI, non-STEMI, and unstable angina pectoris). These results verify the utility of the Risk Index in unselected patients with STEMI, broaden its application to other types of ACSs, and extend its utility to stratification of long-term mortality risk.
authors.affiliation: Cardiovascular Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: Leonard
authors.initials: L
authors.lastname: Ilkhanoff
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: O'Donnell
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Camargo
authors.forename: T David
authors.initials: TD
authors.lastname: O'Halloran
authors.forename: Robert P
authors.initials: RP
authors.lastname: Giugliano
authors.forename: Donald M
authors.initials: DM
authors.lastname: Lloyd-Jones
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000188:drug therapy / Q000401:mortality*; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D011795:Surveys and Questionnaires; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome