Moderate red-wine consumption partially prevents body weight gain in rats fed a hyperlipidic diet.
Red wine is a beverage that can exert a broad spectrum of health-promoting actions both in humans and laboratory animal models if consumed moderately. However, information about its effect on body weight is scarce. We have evaluated the effect of moderate red wine consumption on body weight and energy intake in male Zucker lean rats fed a hypercaloric diet for 8 weeks. For this purpose, we used three 5-animal groups: a high-fat diet group (HFD), a high-fat-diet red-wine-drinking group (HFRWD), and a standard diet group (SD). After 8 weeks, the HFRWD group had a lower body weight gain (175.66 +/- 2.78% vs 188.22 +/- 4.83%; P<.05) and lower energy intake (269.45 +/- 4.02 KJ/animal.day vs day vs 300.81 +/- 4.52 KJ/animal.day; P<.05) and had less fat mass at epididymal location respect to the whole body weight (0.014 +/- 0.001 vs 0.017 +/- 0.001; P<.05) than the HFD group. However, the red wine didn't modified the fed efficiency 0.012 +/- 0.001 g/KJ for HFRWD group versus 0.013 +/- 0.001 g/KJ for the HFD one (P=.080). These findings, though preliminary, show that moderate red wine intake can prevent the increase of body weight by modulating energy intake in a rat diet-induced model of obesity.
Vadillo
Montserrat
M
Department of Biochemistry and Biotechnology, Unitat d'Enologia del Centre de Referència en Tecnologia dels Aliments de la Generalitat de Catalunya, Universitat Rovira i Virgili, 43007 Tarragona, Spain.
Bargalló
Montserrat Vadillo
MV
Ardévol
Anna
A
Grau
Anna Ardévol
AA
Fernández-Larrea
Juan
J
Fernández-Larrea
Juan de Dios
Jde D
Pujadas
Gerard
G
Anguiano
Gerard Pujadas
GP
Bladé
Cinta
C
Segarra
Maria Cinta Bladé
MC
Salvadó
Maria Josepa
MJ
Rovira
Maria Josepa Salvadó
MJ
Arola
Lluís
L
Ferré
Lluia Arola
LA
Blay
Mayte
M
Olivé
Mayte Blay
MB
D050154:Adiposity; D000818:Animals; D004041:Dietary Fats / Q000008:administration & dosage*; D002149:Energy Intake; D004822:Epididymis; D008297:Male; D009765:Obesity / Q000209:etiology / Q000517:prevention & control; D051381:Rats; D011924:Rats, Zucker; D015430:Weight Gain; D014920:Wine
D004041:Dietary Fats