Slow clearance of human parvovirus B19 viremia following acute infection.
Parvovirus B19 is a common, clinically significant pathogen. Reassessment of the viral kinetics after acute infection showed that the virus is not rapidly cleared from healthy hosts, despite early resolution of symptoms. These findings challenge our current conception of the virus' pathogenesis and have implications for the management of the infection.
Lindblom
Anna
A
Department of Medicine, Infectious Disease Unit, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Isa
Adiba
A
Norbeck
Oscar
O
Wolf
Susanne
S
Johansson
Bo
B
Broliden
Kristina
K
Tolfvenstam
Thomas
T
D000328:Adult; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes; D005260:Female; D006801:Humans; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000097:blood*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D013997:Time Factors; D014766:Viremia