Electrochemically promoted C-N bond formation from acetylenic amines and CO2. Synthesis of 5-methylene-1,3-oxazolidin-2-ones.
[reaction: see text] An efficient electrochemical synthesis of 5-methylene-1,3-oxazolidin-2-ones (2a-h) from acetylenic amines (1a-h) and carbon dioxide has been achieved by direct electrolysis of solution of MeCN and Et4NPF6 containing the amine, with subsequent CO2 bubbling and heating. The yields vary from good to excellent, the conditions are mild, and the use of toxic and harmful chemicals and catalysts is avoided.
Feroci
Marta
M
Dip. Ingegneria Chimica, Materiali, Materie Prime e Metallurgia, Università La Sapienza, via Castro Laurenziano, 7, I-00161 Roma, Italy. marta.feroci@uniroma1.it
Orsini
Monica
M
Sotgiu
Giovanni
G
Rossi
Leucio
L
Inesi
Achille
A