Confirmation of the association between male pattern baldness and the androgen receptor gene.
Male pattern baldness (MPB) is a common phenomenon with a complex mode of inheritance. A recent report has implicated the androgen receptor gene in MPB, but this result has not been confirmed. We analyzed a silent polymorphism in the androgen receptor gene (AR) in a group of 41 bald males and 39 non-bald males, and found a significant association (p < 0.0026), thus confirming the previously reported association between MPB and the AR gene.
Levy-Nissenbaum
Etgar
E
Danek Gartner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Israel.
Bar-Natan
Michal
M
Frydman
Moshe
M
Pras
Elon
E
D000328:Adult; D000505:Alopecia / Q000235:genetics*; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide; D011944:Receptors, Androgen / Q000235:genetics*
D011944:Receptors, Androgen