Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay.
The indirect hemagglutination assay routinely used to detect antibodies to Burkholderia pseudomallei was modified to detect cross-reactivity of antibodies to B. pseudomallei, B. mallei, and B. thailandensis antigens. We demonstrate a lack of cross-reactivity between B. pseudomallei and B. thailandensis but marked cross-reactivity between B. pseudomallei and B. mallei.
Tiyawisutsri
Rachaneeporn
R
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Peacock
Sharon J
SJ
Langa
Sayan
S
Limmathurotsakul
Direk
D
Cheng
Allen C
AC
Chierakul
Wirongrong
W
Chaowagul
Wipada
W
Day
Nicholas P J
NP
Wuthiekanun
Vanaporn
V
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D019117:Burkholderia / Q000276:immunology*; D042726:Burkholderia mallei / Q000276:immunology*; D003429:Cross Reactions; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000276:immunology* / Q000382:microbiology; D008875:Middle Aged
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial