title: Measuring surgical recovery: the study of laparoscopic live donor nephrectomy.
abstract: Following laparoscopic donor nephrectomy (LDN), recovery has only been studied using traditional outcomes, subjective and confounded by comorbidity and psychosocial variables. The purpose of this study is to estimate surgical recovery following LDN using standardized, validated instruments and to compare this recovery profile to that obtained with traditional measures. This was a prospective study of patients undergoing LDN at a single institution between September 2001 and January 2004 (n = 35). At baseline and 4 weeks following surgery, functional exercise capacity was measured using the 6-min walk test (6MWT) and health-related quality of life was assessed with the Short Form-36 (SF-36) questionnaire, including physical component summary (PCS) and mental component summary (MCS) scores. Patients' self-assessment of recovery and time to resumption of regular activities was ascertained. At follow-up (median 29 days), patients' 6MWT was lower by a median of 30 m (p = 0.07) and PCS decreased from 57.1 to 42.3 (p = 0.0001), whereas MCS remained constant. Overall, length of stay, return to activities and patient-stated recovery were inadequate outcomes for classifying patient recovery using 6MWT and PCS as the reference standards. Four weeks following LLDN, patients have returned to baseline exercise capacity, but not baseline general physical health. Traditional measures of recovery are incomplete descriptors of recovery.
authors.affiliation: Department of Surgery, McGill University, Montreal, Quebec, Canada.
authors.forename: Simon
authors.initials: S
authors.lastname: Bergman
authors.forename: Liane S
authors.initials: LS
authors.lastname: Feldman
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Mayo
authors.forename: Franco
authors.initials: F
authors.lastname: Carli
authors.forename: Maurice
authors.initials: M
authors.lastname: Anidjar
authors.forename: Dennis R
authors.initials: DR
authors.lastname: Klassen
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Andrew
authors.forename: Melina C
authors.initials: MC
authors.lastname: Vassiliou
authors.forename: Donna D
authors.initials: DD
authors.lastname: Stanbridge
authors.forename: Gerald M
authors.initials: GM
authors.lastname: Fried
mesh_terms: D000328:Adult; D005080:Exercise Test; D005260:Female; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D009399:Nephrons / Q000473:pathology; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D011788:Quality of Life; D012107:Research Design; D011795:Surveys and Questionnaires; D013997:Time Factors; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome; D016138:Walking