No phobias about PhoB activation.
Structures of the inactive and activated forms of the receiver domain of PhoB reported in this issue of Structure (Bachhawat et al., 2005) suggest that the OmpR/PhoB subclass of transcription factors becomes active by dimerization about a symmetric axis utilizing the alpha4-beta5-alpha5 surface.
McCleary
William R
WR
Microbiology and Molecular Biology Department, Brigham Young University, Provo, UT 84602, USA. bill_mccleary@byu.edu
D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D014157:Transcription Factors / Q000737:chemistry* / Q000378:metabolism*
D001426:Bacterial Proteins; D014157:Transcription Factors; C061278:PhoB protein, Bacteria