[Characteristics of methyl-specific PCR-test of glutathione-S-transferase P1 gene in plasm DNA and cellular urinary precipitate for differential diagnosis of prostatic adenoma and adenocarcinoma].
The study was made of possibilities of methyl-specific PCR-test of glutathione-S-transferase P1 (GSTP1) gene in differential diagnosis of prostatic cancer: sensitivity of the test, comparison of reagents of Russian and foreign production. Blood plasm and cellur urinary precipitate DNA was investigated in patients with prostatic adenocarcinoma. The results show that the above test with domestic reagents is rather perspective for differential diagnosis.
Likhin
F A
FA
Bartnovskiĭ
A E
AE
Vdovichenko
K K
KK
Abramov
A A
AA
Belokhvostov
A S
AS
D000230:Adenocarcinoma / Q000175:diagnosis*; D004247:DNA / Q000097:blood / Q000378:metabolism / Q000652:urine; D019175:DNA Methylation; D004273:DNA, Neoplasm / Q000032:analysis* / Q000097:blood / Q000652:urine; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000175:diagnosis; D011471:Prostatic Neoplasms / Q000175:diagnosis*
D004273:DNA, Neoplasm; D004247:DNA