Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
A 67-year-old man, who had widespread and well-defined erythematous violaceous hyperkeratotic plaques on his skin, was diagnosed with borderline tuberculoid leprosy. The patient began treatment with clofazimine, rifampicin, and dapsone, but 15 days afterwards he complained of acral edema with godet sign. Magnetic resonance imaging was done, and the case was interpreted as remitting seronegative symmetrical synovitis with pitting edema. About 8 mg/day of methylprednisolone were started with excellent response.
Helling
Claudia Andrea
CA
Department of Rheumatology, Hospital Bernardino Rivadavia, Borges 2165, 6th-A floor, 1425 Buenos Aires, Argentina. ahelling@intramed.net.ar
Locursio
Ana
A
Manzur
Maria Elena
ME
Sormani de Fonseca
Maria Leticia
ML
D000368:Aged; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004487:Edema / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005528:Foot / Q000473:pathology; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D007918:Leprosy / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D013585:Synovitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
D007917:Leprostatic Agents; D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin; D008775:Methylprednisolone