Intraoperative cortical mapping has low sensitivity for the detection of motor function in proximity to a tumor in the primary motor area.
Six patients with brain tumors within or near the primary motor cortex underwent preoperative functional magnetic resonance imaging (fMRI) and intraoperative cortical mapping, and the accuracy of those techniques for localization of the primary motor cortex and motor function beside the tumor were determined by comparison against neuroanatomical correlates from pre-, intra- and postoperative neurological observations. The location of the primary motor cortex was detected by intraoperative cortical mapping in 5 of 6 cases and by fMRI in all 6 cases. Brain mapping provided equivocal information on the cortical representation of motor territories, and with the technique used in close proximity to the tumor, the motor territories were not detected in all but 1 case. In contrast, the areas controlling motor function in close proximity to the tumor were detected by fMRI in 4 of 6 cases. These data indicate that intraoperative cortical mapping has a low sensitivity for the detection of motor function in the area beside the tumor. Therefore, this technique may not be sufficient to prevent compromise of motor areas during tumor resection.
Shinoura
N
N
Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan. shinoura@cick.jp
Yamada
R
R
Kodama
T
T
Suzuki
Y
Y
Takahashi
M
M
Yagi
K
K
D000368:Aged; D001931:Brain Mapping; D002277:Carcinoma / Q000150:complications / Q000503:physiopathology* / Q000556:secondary / Q000601:surgery; D003399:Craniotomy; D004401:Dysarthria / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D009043:Motor Activity / Q000502:physiology*; D009044:Motor Cortex / Q000473:pathology / Q000503:physiopathology*; D009069:Movement Disorders / Q000209:etiology / Q000517:prevention & control; D009837:Oligodendroglioma / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D010291:Paresis / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D011300:Preoperative Care; D012640:Seizures / Q000209:etiology / Q000503:physiopathology; D012680:Sensitivity and Specificity; D013060:Speech / Q000502:physiology; D015173:Supratentorial Neoplasms / Q000150:complications / Q000503:physiopathology* / Q000556:secondary / Q000601:surgery; D014202:Tremor / Q000209:etiology / Q000503:physiopathology