title: Porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease: case report.
abstract: BACKGROUND
  Chronic arsenism with Bowen's disease is often seen in patients who drink water containing a high level of arsenic. Inorganic arsenic has demonstrated an increased risk of skin cancer.
  
  
  OBJECTIVE
  We present a rare case of porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease.
  
  
  METHODS
  Report of a case and review of the literature.
  
  
  RESULTS
  A case of porocarcinoma arising in a patient with chronic arsenism is presented. The tumor was completely excised by means of wide excision with a 5 mm free margin. The surgical defect was reconstructed with a rhombic flap.
  
  
  CONCLUSIONS
  Chronic arsenism can induce various skin neoplasms, possibly including porocarcinoma.
authors.affiliation: Department of Dermatology, Veterans General Hospital, Kaohsiung, Taiwan. chenishu@sina.com.tw
authors.forename: I-Shu
authors.initials: IS
authors.lastname: Chen
authors.forename: Hung-Wen
authors.initials: HW
authors.lastname: Kuo
authors.forename: Hock-Liew
authors.initials: HL
authors.lastname: Eng
mesh_terms: D020261:Arsenic Poisoning / Q000150:complications*; D001913:Bowen's Disease / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D004439:Eccrine Glands; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D013544:Sweat Gland Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery