Accidental provocation of phaeochromocytoma: the forgotten hazard of metoclopramide?
The perilous potential of metoclopramide when used inadvertently in patients harbouring phaeochromocytomas goes largely under-recognised. Despite the rarity of phaeochromocytoma, clinicians should exercise caution in the use of metoclopramide among hypertensives and those with labile blood pressures, given the potentially life-threatening crisis it can readily evoke in those with this tumour. We report a series of three patients with phaeochromocytoma who developed acute crises from metoclopramide.
Leow
M K
MK
Department of Endocrinology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. mleowsj@massmed.org
Loh
K C
KC
D000310:Adrenal Gland Neoplasms / Q000139:chemically induced*; D000328:Adult; D000932:Antiemetics; D000075202:Contraindications; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008787:Metoclopramide / Q000009:adverse effects*; D008875:Middle Aged; D010673:Pheochromocytoma / Q000139:chemically induced*
D000932:Antiemetics; D008787:Metoclopramide