[Gianotti-Crosti syndrome in an infant following immunization].
Gianotti-Crosti syndrome (GCS), first described by F. Gianotti in 1955, was originally reported to be associated with hepatitis B virus infection in children. The typical clinical picture allows diagnosis of GCS at first glance. The pathogenesis is still unknown. Besides HBV infection, a large number of infectious agents, mostly viruses, have been described as a trigger of GCS. Here we report the occurrence of GCS in an infant five days after the fourth immunization against poliomyelitis, DTPa, Hib, hepatitis B and Streptococcus pneumoniae. Our data and review of the literature suggest that GCS is rarely associated with immunizations, especially when performed with inactivated vaccines.
Schwerk
N
N
Universitätsklinik und Poliklinik für Kinder und Jugendliche Leipzig. nicolaus.schwerk@medizin.uni-leipzig.de
Schwerk
C
C
Vogler
L
L
Schuster
V
V
D000169:Acrodermatitis / Q000175:diagnosis / Q000209:etiology*; D000367:Age Factors; D005500:Follow-Up Studies; D006801:Humans; D007114:Immunization / Q000009:adverse effects*; D007223:Infant; D008297:Male; D013997:Time Factors