title: Uremic pruritus in the chronic renal failure patients.
abstract: Chronic renal failure is connected with various cutaneous symptoms, of which the persistent pruritus is regarded as the most distressing and severily affecting the quality of life. The pathophysiology of uremic pruritus is poorly understood but believed to result from metabolic disequilibrium, increased release of pruritogenic mediators and altered balance between the opioid receptors. Several methods of controlling pruritus are considered, including pharmacologic and nonpharmacologic options, but their efficacy is still unsatisfactory.
authors.affiliation: Department of Dermatology, Skubiszewski Medical University of Lublin.
authors.forename: Grazyna
authors.initials: G
authors.lastname: Chodorowska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wysokiński
authors.forename: Janusz
authors.initials: J
authors.lastname: Chodorowski
mesh_terms: D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000628:therapy; D010530:Peritoneal Dialysis; D011537:Pruritus / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006435:Renal Dialysis; D012307:Risk Factors; D014511:Uremia / Q000175:diagnosis* / Q000628:therapy