The use of fluor-hydroxy pulse peel in actinic porokeratosis.
BACKGROUND
The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions.


OBJECTIVE
The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis.


METHODS
A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses.


RESULTS
Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia.


CONCLUSIONS
The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.
Teixeira
Solange P
SP
Department of Dermatologym Cosmiatry Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil. solangeteixeira@clinderm.com.br
de Nascimento
Maurício M
MM
Bagatin
Ediléia
E
Hassun
Karime M
KM
Talarico
Sérgio
S
Michalany
Nilceo
N
D001706:Biopsy; D002615:Chemexfoliation / Q000379:methods*; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006016:Glycolates / Q000627:therapeutic use*; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008875:Middle Aged; D017499:Porokeratosis / Q000188:drug therapy* / Q000209:etiology; D012867:Skin / Q000473:pathology; D014466:Ultraviolet Rays / Q000009:adverse effects
D006016:Glycolates; D007641:Keratolytic Agents; C031149:glycolic acid; D005472:Fluorouracil