title: Separation of some chiral flavonoids by microbial cyclosophoraoses and their sulfated derivatives in micellar electrokinetic chromatography.
abstract: Neutral cyclosophoraoses (Cys) and highly sulfated cyclosophoraoses (HS-Cys) were successfully applied as chiral selectors with SDS for the separation of some chiral flavonoids in MEKC. HS-Cys were synthesized by the chemical modification of a family of neutral Cys isolated from a soil microorganism, Rhizobium meliloti 2011. Chiral catechin was separated with a resolution (R(s)) of 0.754 by neutral Cys and SDS. In the case of isosakuranetin and neohesperidin, resolution (R(s)) values of 1.483 and 1.306 were obtained with HS-Cys and SDS, respectively.
authors.affiliation: Department of Advanced Technology Fusion, Bio/Molecular Informatics Center, Konkuk University, Seoul, Korea.
authors.forename: Heylin
authors.initials: H
authors.lastname: Park
authors.forename: Seunho
authors.initials: S
authors.lastname: Jung
mesh_terms: D002392:Catechin / Q000302:isolation & purification; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D005419:Flavonoids / Q000302:isolation & purification*; D005936:Glucans / Q000737:chemistry; D006569:Hesperidin / Q000302:isolation & purification; D047028:Macrocyclic Compounds / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry; D013237:Stereoisomerism; D013431:Sulfates; D000094162:Phytoalexins
chemical_list: D002392:Catechin; D005419:Flavonoids; D005936:Glucans; D006569:Hesperidin; D047028:Macrocyclic Compounds; D011134:Polysaccharides; D013431:Sulfates; C099724:sakuranetin; D000094162:Phytoalexins