title: Pisa syndrome without neuroleptic exposure in a patient with Parkinson's disease: case report.
abstract: We report on a patient affected by Parkinson's disease who developed over a period of a few weeks a tonic deviation of her head, neck, and trunk fitting the typical description of Pisa syndrome (PS). This patient was under stable levodopa and pramipexole treatment and had never been exposed to any psychotropic or antiemetic drugs before or at the time she developed the postural abnormality. Because dopamine transporter imaging revealed bilateral and symmetrical reduction of striatal uptake, we suggest that PS is not primarily related to side differences in dopaminergic denervation or drug exposure.
authors.affiliation: Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Università di Verona, Verona, Italy.
authors.forename: Mattia
authors.initials: M
authors.lastname: Gambarin
authors.forename: Angelo
authors.initials: A
authors.lastname: Antonini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Moretto
authors.forename: Paolo
authors.initials: P
authors.lastname: Bovi
authors.forename: Silvia
authors.initials: S
authors.lastname: Romito
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiaschi
authors.forename: Michele
authors.initials: M
authors.lastname: Tinazzi
mesh_terms: D000368:Aged; D000978:Antiparkinson Agents / Q000008:administration & dosage* / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D002540:Cerebral Cortex / Q000503:physiopathology; D003342:Corpus Striatum / Q000503:physiopathology; D050483:Dopamine Plasma Membrane Transport Proteins / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004422:Dystonia Musculorum Deformans / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage* / Q000009:adverse effects; D010300:Parkinson Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D013577:Syndrome; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D050483:Dopamine Plasma Membrane Transport Proteins; D007980:Levodopa