title: Neonatal diabetes mellitus: Insulin pump as an alternative management strategy.
abstract: Neonatal diabetes mellitus (hyperglycaemia within the first month of life, with an insulin requirement) may be transient or permanent. Management is complex, due to lack of subcutaneous fat and the need for small doses of insulin, and may be complicated by additional medical problems. Three cases are presented, the first of which was treated with conventional insulin therapy. The latter two were successfully treated with subcutaneous insulin pump therapy. We present suggested guidelines for treatment of neonatal diabetes, using this novel approach to management.
authors.affiliation: Centre for Hormone Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
authors.forename: Tara
authors.initials: T
authors.lastname: Bharucha
authors.forename: Justin
authors.initials: J
authors.lastname: Brown
authors.forename: Ciara
authors.initials: C
authors.lastname: McDonnell
authors.forename: Robecca
authors.initials: R
authors.lastname: Gebert
authors.forename: Peter
authors.initials: P
authors.lastname: McDougall
authors.forename: Fergus
authors.initials: F
authors.lastname: Cameron
authors.forename: George
authors.initials: G
authors.lastname: Werther
authors.forename: Margaret
authors.initials: M
authors.lastname: Zacharin
mesh_terms: D003920:Diabetes Mellitus / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D007231:Infant, Newborn; D007279:Injections, Subcutaneous; D007328:Insulin / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008297:Male; D047928:Premature Birth; D016896:Treatment Outcome
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin