title: Psychological risk factors of incidence of breast cancer: a prospective cohort study in Finland.
abstract: BACKGROUND
  Belief that depression and other psychological factors predict breast cancer is common, but there have been few prospective epidemiological studies on this relationship.
  
  
  METHODS
  The relationship between depression, personality traits, illness attitudes, life events and health history, and breast cancer risk was studied in a prospective, 6-9 year follow-up of a cohort study of 10892 Finnish women of 48-50 years of age at the baseline. Cancer cases were obtained from the Cancer Registry of Finland. Multivariate logistic regression analysis was performed controlling for socioeconomic factors, family history of cancer, parity, and health behaviours.
  
  
  RESULTS
  Breast cancer incidence in the cohort was 1.15 times the average in age group 50-59. There was no evidence of depression, trait anxiety, cynical distrust, or coping being significant predictors of breast cancer incidence.
  
  
  CONCLUSIONS
  In this cohort study with the 6-9 year follow-up, psychological factors such as depression, trait anxiety, cynical distrust, or coping did not increase breast cancer risk.
authors.affiliation: Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland. arja.aro@ktl.fi
authors.forename: A R
authors.initials: AR
authors.lastname: Aro
authors.forename: H J
authors.initials: HJ
authors.lastname: De Koning
authors.forename: M
authors.initials: M
authors.lastname: Schreck
authors.forename: M
authors.initials: M
authors.lastname: Henriksson
authors.forename: A
authors.initials: A
authors.lastname: Anttila
authors.forename: E
authors.initials: E
authors.lastname: Pukkala
mesh_terms: D000223:Adaptation, Psychological; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000523:psychology*; D015331:Cohort Studies; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012042:Registries; D012307:Risk Factors; D011795:Surveys and Questionnaires