Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris.
OBJECTIVE
To investigate the effects of triptolide tablet in the treatment of patients with psoriasis vulgaris.


METHODS
By an open clinical study of 103 patients with psoriasis vulgaris. Psoriasis area severity index (PASI) was measured and recorded before and after treatment for efficacy evaluation.


RESULTS
Of the 103 patients, markedly effective was got in 41 (39.7%), improved in 37 (35.8%) and ineffective in 25 (24.5%), the total effective rate being 75.7%, and the adverse reaction was shown only in few patients with decreased WBC during the treatment period.


CONCLUSIONS
Triptolide tablet is effective for the treatment of psoriasis vulgaris during the one-year follow-up.
Wu
Shao-xi
SX
Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College, Nanjing. shaoxiwu@yahoo.com
Guo
Ning-ru
NR
D000293:Adolescent; D000328:Adult; D000368:Aged; D004224:Diterpenes / Q000008:administration & dosage* / Q000009:adverse effects; D004852:Epoxy Compounds; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010616:Phenanthrenes / Q000008:administration & dosage* / Q000009:adverse effects; D011565:Psoriasis / Q000188:drug therapy*; D013607:Tablets; D016896:Treatment Outcome
D004224:Diterpenes; D004852:Epoxy Compounds; D007166:Immunosuppressive Agents; D010616:Phenanthrenes; D013607:Tablets; C001899:triptolide