The effect of extremely low-frequency magnetic field on motor activity of rats in the open field.
Exposure to extremely low-frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) for seven days did not change spontaneous motor activity of rats in the open field compared to sham-exposed animals. Pre-exposure to ELF-MF decreased locomotor and stereotypic activity induced by amphetamine (1.5 mg/kg body weight) and accordingly increased the resting time compared to sham-exposed and amphetamine-treated rats. Vertical activity (rearing) of these two groups was similar. Our results indicate that ELF-MF has different effects on some parameters of amphetamine-induced motor activity, probably due to brain region-specific effects on catecholaminergic systems responsible for movement control.
Prolić
Zlatko
Z
Institute for Biological Research, Sinisa Stankovic, Belgrade, Serbia and Montenegro.
Janać
Branka
B
Pesić
Vesna
V
Jelenković
Ankica
A
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects*; D002395:Catecholamines / Q000378:metabolism; D000697:Central Nervous System Stimulants / Q000494:pharmacology; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields; D009043:Motor Activity / Q000187:drug effects / Q000528:radiation effects*; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects / Q000528:radiation effects*
D002395:Catecholamines; D000697:Central Nervous System Stimulants; D000661:Amphetamine