title: Biologically active compounds of fungal origin displaying antitumor activity.
abstract: This review describes biologically active natural products displaying antitumor activities derived from fruit bodies and cultured mycelium of macromycetes. Among these compounds the most important are: polisaccharides, phenols, terpenes and others. Polysaccharides produce their antitumor effects by activating different immune responses in the host. Other compounds are examples of cytotoxic and immunomodulating activities.
authors.affiliation: Jagiellonian University, Collegium Medicum, Department of Pharmaceutical Botany, 9 Medyczna Str, 30-688 Kraków, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Sułkowska-Ziaja
authors.forename: Bozena
authors.initials: B
authors.lastname: Muszyńska
authors.forename: Grazyna
authors.initials: G
authors.lastname: Końska
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005658:Fungi / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D001685:Biological Factors