[A gene-chip image grid localization method based on profiles of image].
Automatic gene-chip image grid localization is an essential task for gene-chip image analysis. Now an method based on profiles of gene-chip image is proposed. Using the differences between two profiles after filtration by arithmetic mean method, we can easily find the local grayscale minimum between two probe spots, then the probe spots are automatically located. The experiments show that the new approach correctly locates the probes while giving protection against noise affection robustly. Grid location
Hu
Yuanyuan
Y
Department of Biomedical Engineering, Southeast University, Nanjing 210096, China. rosebud-hu@sohu.com
Sun
Xiao
X
He
Nongyue
N
Tang
Jianxin
J
D000465:Algorithms; D020869:Gene Expression Profiling / Q000379:methods*; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*