title: Evolution of NAD biosynthetic enzymes.
abstract: Two research groups have solved crystal structures of nicotinic acid phosphoribosyltransferase (PRTase) and made the argument that PRTases in three distinct pathways of nicotinamide adenine dinucleotide (NAD) biosynthesis evolved from a common ancestor (Shin et al., 2005 and Chappie et al., 2005).
authors.affiliation: Department of Genetics, Dartmouth Medical School,Lebanon, NH 03756, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Brenner
mesh_terms: D019143:Evolution, Molecular; D009243:NAD / Q000096:biosynthesis*; D010430:Pentosyltransferases / Q000737:chemistry* / Q000235:genetics*; D011487:Protein Conformation
chemical_list: D009243:NAD; D010430:Pentosyltransferases; C021864:nicotinate phosphoribosyltransferase