Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe.
The spread of the plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 was detected in Acinetobacter sp. clinical isolates from southern Europe, the Balkans, and central Turkey. It may contribute significantly to the emergence of carbapenem resistance in Acinetobacter spp., at least in this part of the world.
Marqué
Sophie
S
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Le-Kremlin-Bicêtre, France.
Poirel
Laurent
L
Héritier
Claire
C
Brisse
Sylvain
S
Blasco
Maria Dolores
MD
Filip
Roxana
R
Coman
Gabriela
G
Naas
Thierry
T
Nordmann
Patrice
P
D000150:Acinetobacter / Q000187:drug effects* / Q000201:enzymology*; D000151:Acinetobacter Infections / Q000453:epidemiology / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015780:Carbapenems / Q000378:metabolism* / Q000494:pharmacology; D005060:Europe / Q000453:epidemiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D015780:Carbapenems; D001618:beta-Lactamases; C108449:oxacillinase