title: Fixation topography in normal test persons.
abstract: BACKGROUND
  The eye is moved so that the object of interest falls on the central fovea, where the spatial resolution is highest. In the present study we quantified eye movements of normal test persons during steady fixation and characterized the fixation using a 3D fixation plot (X horizontal eye position, Y vertical eye position, Z time in each eye position).
  
  
  METHODS
  Fixation eye movements were quantified binocularly in ten normal test persons during a 40-s fixation task using an infrared recording technique.
  
  
  RESULTS
  The fixation plot was characterized by a single preferred fixation locus in 17 eyes. One eye had two distinctly separated preferred fixation locations and in two eyes the configuration of fixation plot was flat with no single identifiable locus of fixation. The fixation plots were elliptical along the horizontal meridian in 9 eyes, elliptical along the vertical meridian in 8 eyes, and round in 3 eyes. The fixation area (RAF95) ranged between 1418 and 14182 arcmin(2), and a significant positive correlation was found between RAF95 and the mean microsaccadic amplitude (p<0.001).
  
  
  CONCLUSIONS
  The fixation plots are often characterized by a single preferred fixation locus but may also be almost flat with no identifiable location of fixation. The individual fixations patterns resembles the cone density contour plots as found in histological studies, and it may be speculated, that the shape of the fixation plot is determined by the cone density topography.
authors.affiliation: Department of Ophthalmology, Odense University Hospital, Sdr Boulevard, 5000, Odense C, Denmark. f.moeller@dadlnet.dk
authors.forename: F
authors.initials: F
authors.lastname: Møller
authors.forename: M L
authors.initials: ML
authors.lastname: Laursen
authors.forename: A K
authors.initials: AK
authors.lastname: Sjølie
mesh_terms: D000328:Adult; D005133:Eye Movements / Q000502:physiology*; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D014787:Vision Tests / Q000379:methods; D015348:Vision, Binocular / Q000502:physiology