Disseminated Ochroconis gallopavum infection in a chronic lymphocytic leukemia: a case report and review of the literature on hematological malignancies.
Disseminated fungal infection is an important cause of morbidity and mortality among patients with hematological malignancies. Ochroconis gallopavum is a dematiaceous and thermotolerant fungus that causes opportunistic infections in immunocompromised hosts. About only 30 cases of this organism infection have been reported worldwide. We report a disseminated Ochroconis gallopavum infection in a B-cell chronic lymphocytic leukemia patient. In spite of intensive anti-fungal treatment, no improvement in the clinical condition was observed and the patient died 4 months after diagnosis of the infection. Ochroconis gallopavum infection is a potentially fatal disease in hematological malignancies.
Fukushima
Noriyasu
N
Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
Mannen
Kotaro
K
Okamoto
Sumiaki
S
Shinogi
Taro
T
Nishimoto
Katsutaro
K
Sueoka
Eisaburo
E
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification; D017809:Fatal Outcome; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications; D006801:Humans; D016867:Immunocompromised Host; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000276:immunology; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D009894:Opportunistic Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology
D000935:Antifungal Agents