title: [The reliability of stereotaxy in diagnosis of intracranial space occupying lesions].
abstract: A total of 79 patients with a suspect space occupying intracranial lesion was operated stereotactically. After CT and MR image acquisition, entry and target coordinates were defined and biopsy trajectories were simulated preoperatively using a special planning software. Biopsy specimens allowed a satisfactory neuropathological examination and diagnostic result in 74 of 79 (93.7%) cases. In the remaining 5 of 79 (6.3%) patients, a glioses was diagnosed in three cases; in only two patients could no pathological process be proved. 10 of 79 (12.7%) patients showed an intraoperative bleeding out of the biopsy-cannula during serial stereotaxy, which was associated with a CT-detectable hematoma up to 7 mm in diameter in only three cases (3.8%). In no patient was the detection of intracerebral bleeding the reason for any neurological deficit. In summary, the high percentage of satisfactory neuropathological diagnoses, the low rate of stereotaxy-associated morbidity and the comfortable and safe use of computer and stereotactic devices justify this kind of minimally invasive diagnostic measure as a routine method.
authors.affiliation: Klinik und Poliklinik für Neurochirurgie, Universität Leipzig, Deutschland. wind@medizin.uni-Leipzig.de
authors.forename: Dirk
authors.initials: D
authors.lastname: Winkler
authors.forename: Dirk
authors.initials: D
authors.lastname: Lindner
authors.forename: Kathrin
authors.initials: K
authors.lastname: Geiger
authors.forename: Andreas
authors.initials: A
authors.lastname: Richter
authors.forename: Ralf
authors.initials: R
authors.lastname: Schober
authors.forename: Jürgen
authors.initials: J
authors.lastname: Meixensberger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002543:Cerebral Hemorrhage / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D038361:Neuronavigation; D012984:Software; D025321:Surgery, Computer-Assisted; D014057:Tomography, X-Ray Computed