Some new aspects of the Boyer reaction.
[reaction: see text] The reaction outcome of 2-azidoethanol and aliphatic aldehyde is found to be dependent on the catalyst and the structure of the azido alcohol. Under the catalysis of Cu(II) triflate, the corresponding acetal is obtained. A similar reaction between 2-aryl-2-azidoethanol and aldehyde catalyzed by BF3 yields a mixture of 3-oxazoline and 2-oxazoline. The latter reaction has been used for the preparation of 3-oxazolines in good enantioselectivity.
Chakraborty
Rupak
R
Department of Chemistry, University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, Texas 78249-0698, USA.
Franz
Veronica
V
Bez
Ghanashyam
G
Vasadia
Dipali
D
Popuri
Chenchu
C
Zhao
Cong-Gui
CG