title: [Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report].
abstract: An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstrable. However, on account of the initial normal laboratory test of emostases, the partial correction of the prothrombin time with 50% normal plasma in vitro and the family history, the congenital deficiency in factor VII was ruled out. Whatever the mechanism involved, this factor VII deficiency was related to malignancy.
authors.affiliation: Laboratoire général Hôpital A. Mami Ariana.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Zili
authors.forename: Sadok
authors.initials: S
authors.lastname: Hammami
authors.forename: Adel
authors.initials: A
authors.lastname: Marghli
authors.forename: Lamia
authors.initials: L
authors.lastname: Mechmech
authors.forename: Louisa
authors.initials: L
authors.lastname: Boughnim
authors.forename: Salem
authors.initials: S
authors.lastname: Abid
authors.forename: N'siri
authors.initials: N
authors.lastname: Brahim
authors.forename: Nour El Houda
authors.initials: Nel H
authors.lastname: Toumi
authors.forename: Tarek
authors.initials: T
authors.lastname: Kilani
authors.forename: Sadok
authors.initials: S
authors.lastname: Yaalaoui
mesh_terms: D005168:Factor VII Deficiency / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged