title: Renal (uremic) encephalopathy in a goat.
abstract: Renal encephalopathy was diagnosed in a 2-year-old male boar goat with a history of chronic weight loss and ataxia. Histopathological examination of the brain revealed a striking myelin vacuolation distributed mainly in two patterns: (i) along the junction of the neocortex and corona radiata, and (ii) in the bundles of the internal capsule as it dissects through the basal nuclei. The kidneys had diffuse severe tubular and glomerular necrosis and degeneration. The neural lesions are consistent with renal (uremic) encephalopathy. To the authors' knowledge, this is the first report of renal encephalopathy in a goat.
authors.affiliation: Pfizer Global R and D, 2800 Plymouth Road, Building 35/191, Ann Arbor, MI 48105, USA. zaher.radi@pfizer.com
authors.forename: Z A
authors.initials: ZA
authors.lastname: Radi
authors.forename: B V
authors.initials: BV
authors.lastname: Thomsen
authors.forename: B A
authors.initials: BA
authors.lastname: Summers
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D015511:Goat Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D006041:Goats; D007150:Immunohistochemistry / Q000662:veterinary; D007668:Kidney / Q000737:chemistry / Q000473:pathology; D007674:Kidney Diseases / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D008297:Male