title: Genetic comparison of H5N1 influenza A viruses isolated from chickens in Japan and Korea.
abstract: Outbreaks of highly pathogenic avian influenza (HPAI) caused by H5N1 virus occurred during 2003 to 2004 in Korea and Japan. The H5N1 viruses isolated in both countries were genetically similar at > 99% identity in the nucleotide sequences of all eight RNA segments, indicating that they belong to genotype V and are distinct from HPAI viruses prevalent in southeast Asia that belong to genotype Z. These findings indicate that the H5N1 viruses that caused the HPAI outbreaks in both Korea and Japan were derived from a common ancestor.
authors.affiliation: Department of Infectious Diseases, National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba, Ibaraki, Japan. masema@affrc.go.jp
authors.forename: Masaji
authors.initials: M
authors.lastname: Mase
authors.forename: Jae-Hong
authors.initials: JH
authors.lastname: Kim
authors.forename: Youn-Jeong
authors.initials: YJ
authors.lastname: Lee
authors.forename: Kenji
authors.initials: K
authors.lastname: Tsukamoto
authors.forename: Tadao
authors.initials: T
authors.lastname: Imada
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Imai
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yamaguchi
mesh_terms: D000818:Animals; D002645:Chickens / Q000821:virology*; D005838:Genotype; D006389:Hemagglutinins, Viral / Q000032:analysis; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D005585:Influenza in Birds / Q000821:virology*; D007564:Japan; D007723:Korea; D009439:Neuraminidase / Q000032:analysis; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014764:Viral Proteins / Q000032:analysis
chemical_list: D006389:Hemagglutinins, Viral; D012367:RNA, Viral; D014764:Viral Proteins; D009439:Neuraminidase