title: Modified histologic technique for processing metallic coil-bearing tissue.
abstract: We developed a modified paraffin-embedding histologic technique for processing metallic coil-bearing aneurysm tissues. This modified technique was successfully employed for processing platinum coil-bearing tissue for 30 rabbit aneurysms and 6 swine aneurysms. This technique for sectioning coil-bearing aneurysms resulted in little or no tissue distortion and permitted good preservation of morphology and application of multiple advanced staining techniques. This technique is considered beneficial for studying the molecular mechanisms of aneurysm healing after coiling.
authors.affiliation: Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Daying
authors.initials: D
authors.lastname: Dai
authors.forename: Yong Hong
authors.initials: YH
authors.lastname: Ding
authors.forename: Mark A
authors.initials: MA
authors.lastname: Danielson
authors.forename: Ramanathan
authors.initials: R
authors.lastname: Kadirvel
authors.forename: Debra A
authors.initials: DA
authors.lastname: Lewis
authors.forename: Harry J
authors.initials: HJ
authors.lastname: Cloft
authors.forename: David F
authors.initials: DF
authors.lastname: Kallmes
mesh_terms: D000818:Animals; D002340:Carotid Artery Diseases / Q000473:pathology* / Q000628:therapy*; D017536:Carotid Artery, Common; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D006652:Histological Techniques / Q000592:standards; D002532:Intracranial Aneurysm / Q000473:pathology* / Q000628:therapy*; D016612:Paraffin Embedding; D010984:Platinum; D011817:Rabbits; D013194:Staining and Labeling; D013552:Swine
chemical_list: D010984:Platinum