Therapy-resistant psoriasis treated with alefacept and subsequent narrow band ultraviolet B phototherapy with total clearing of psoriasis.
Combinations of therapeutic modalities have been utilized to meet the challenge of difficult to treat psoriasis. We report two cases of psoriasis, resistant to methotrexate and monotherapy with UVB, treated effectively with alefacept and concomitant narrow band UVB resulting in total disease clear.
Scheinfeld
Noah
N
St Lukes Roosevelt Hospital Center, New York, NY, USA. Scheinfeld@earthlink.net
D000328:Adult; D000077944:Alefacept; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000628:therapy*; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use*; D012074:Remission Induction; D014467:Ultraviolet Therapy
D011993:Recombinant Fusion Proteins; D000077944:Alefacept