[Surgical treatment and survival analysis of recurrent carcinoma within gastric remnant:a report of 60 cases].
OBJECTIVE
To study the surgical treatment effect and factors influencing prognosis of recurrent carcinoma within gastric remnant.


METHODS
From 1990 to 2003, clinical data of 60 patients underwent surgical operation again because of recurrence carcinoma within gastric remnant after radical resection were reviewed retrospectively.


RESULTS
The mean survival time was 32.6 months and the median survival time was 27.0 months. Thirty-seven patients (61.7%) received radical resection with the mean survival time of 45.0 months. Twenty-three patients received palliative treatment with the mean survival time of 12.7 months (P< 0.001). Univariate analysis showed that the clinical stages, pathologic classification, radical resection, peritoneal seeding, liver metastasis, the expression of CD44v6, PCNA and MVD were significantly correlated with survival time (P< 0.01), but were not correlated with sex,age,recurrence time after the first operation (P> 0.05). Multivariate analysis revealed that the clinical stages, peritoneal seeding and radical resection were independent prognostic factors.


CONCLUSIONS
The clinical stages, peritoneal seeding and radical resection are independent prognostic factors of recurrent carcinoma within gastric remnant. The radical resection maybe the most effective way to treat the recurrent carcinoma within gastric remnant.
Du
Yi-an
YA
Department of Hepatobiliary Pancreatic and Gastric Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China. duyajim@hotmail.com
Guo
Jian-min
JM
Zhang
Yun-li
YL
Zhou
Li-xin
LX
Zhang
Ze-wei
ZW
Wang
Xin-bao
XB
Hu
Jian-guo
JG
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018365:Neoplasm, Residual; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis