title: Probing specific lipid-protein interaction by saturation transfer difference NMR spectroscopy.
abstract: We studied the interaction of mono- and polyunsaturated phosphatidylcholines with rhodopsin by 1H NMR saturation transfer difference spectroscopy with magic angle spinning (STD-MAS NMR). The results indicate a strong preference for interaction of rhodopsin with the polyunsaturated docosahexaenoic acid.
authors.affiliation: Laboratory of Membrane Biochemistry and Biophysics, NIAAA, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: Olivier
authors.initials: O
authors.lastname: Soubias
authors.forename: Klaus
authors.initials: K
authors.lastname: Gawrisch
mesh_terms: D000818:Animals; D002417:Cattle; D005997:Glycerylphosphorylcholine / Q000031:analogs & derivatives* / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D012243:Rhodopsin / Q000737:chemistry*
chemical_list: C505696:1-palm-itoyl-d31-2-oleoyl-sn-glycero-3-phosphocholine; C505695:1-stearoyl-d35-2-docosahexaenoyl-sn-glycero-3-phosphocholine; D005997:Glycerylphosphorylcholine; D012243:Rhodopsin