Innovation: Photoactivatable fluorescent proteins.
The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.
Lukyanov
Konstantin A
KA
Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia. kluk@ibch.ru
Chudakov
Dmitry M
DM
Lukyanov
Sergey
S
Verkhusha
Vladislav V
VV
D000818:Animals; D005453:Fluorescence; D008164:Luminescent Proteins / Q000032:analysis* / Q000737:chemistry* / Q000235:genetics; D010777:Photochemistry / Q000379:methods*
D008164:Luminescent Proteins