title: Selective deacetylation of zaluzanin D using transformed Escherichia coli cultures.
abstract: The use of conventional and unconventional reaction methodology for the hydrolysis of the acetate group in zaluzanin D resulted in hydration of the 11,13 exocyclic bond along with deacetylation. But the microorganism E. coli selectively cleaved the acetate group to yield zaluzanin C.
authors.affiliation: Department of Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India.
authors.forename: Munuswamy Ramanujam
authors.initials: MR
authors.lastname: Ganesh
authors.forename: Jothi
authors.initials: J
authors.lastname: Arunachalam
authors.forename: Anand
authors.initials: A
authors.lastname: Krithika
authors.forename: Sundarajan Sundar
authors.initials: SS
authors.lastname: Rajan
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane
chemical_list: D000935:Antifungal Agents; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C000621518:zaluzanin C; C474047:zaluzanin-D