[Consensus document from GESITRA-SEIMC on the prevention and treatment of cytomegalovirus infection in transplanted patients].
Cytomegalovirus (CMV) infection remains an important complication of transplantation. The last decade has been characterized by improvements to management that has reduced its morbidity and mortality. The advance has been particularly important in the diagnosis and prevention. Several techniques have been developed that allow the increasingly rapid and sensitive diagnosis. The different preventive strategies include use of appropriate blood products, immune globulin, and antiviral agents either as prophylaxis or pre-emptive therapy. The development of effective oral drugs as valganciclovir also represents a new advance. It is necessary to summarize these advances to facilitate the development of local policies reflecting recent changes. The Group of Study of Infections in Transplantation (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) has therefore produced actual recommendations in the management of CMV infection after transplantation.
Torre-Cisneros
Julián
J
Unidad de Enfermedades Infecciosas, Hospital Reina Sofía, Córdoba, España. julian.torre.sspa@juntadeandalucia.es
Fortún
Jesús
J
Aguado
José María
JM
de la Cámara
Rafael
R
Cisneros
José Miguel
JM
Gavaldá
Joan
J
Gurguí
Mercé
M
Lumbreras
Carlos
C
Martín
Carmen
C
Martín-Dávila
Pilar
P
Montejo
Miguel
M
Moreno
Asunción
A
Muñoz
Patricia
P
Pahissa
Albert
A
Pérez
José Luis
JL
Rovira
Montserrat
M
Bernardos
Angel
A
Gil-Vernet
Salvador
S
Quijano
Yolanda
Y
Rábago
Gregorio
G
Román
Antoni
A
Varó
Evaristo
E
D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D016867:Immunocompromised Host; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control* / Q000821:virology; D016377:Organ Transplantation; D012307:Risk Factors
D000998:Antiviral Agents