[Effect of immune-enhanced enteral diet on postoperative immunological function in patients with colorectal cancer].
OBJECTIVE
To explore the influence of immune-enhanced enteral diet on postoperative metabolism and immunological function in colorectal tumor patient.


METHODS
Seventy-two patients with colorectal cancer were enrolled in this study. Immune-enhanced enteral diet was administrated in 36 cases (study group), while regular enteral nutrition (EN) was given in 36 cases (control group). The immunological function, inflammatory function and nutrition index were evaluated before operation and on postoperative day 1 and day 8.


RESULTS
Serum levels of glutamine, asparagines, CD4 (+), NK, IgG, IgM were higher in the study group than those in the control group. The levels of IL- 6, TNF-alpha in the study group were lower than those in the control group. The difference was statistically significant (P< 0.05).


CONCLUSIONS
Immune-enhanced enteral diet can ameliorate the cell immunological and fluid immunological function in the patients with colorectal cancer after the procedures.
Chen
Rong
R
Department of Coloproctology, The Second Affiliated Hospital, Wenzhou Medical College, Wenzhou 325000, China. cr13806887833@163.com
Cai
Jing-li
JL
Zhou
Bin
B
Jiang
Ai-fen
AF
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001120:Arginine / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000178:diet therapy* / Q000276:immunology*; D004750:Enteral Nutrition; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use; D005260:Female; D005973:Glutamine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period
D015525:Fatty Acids, Omega-3; D005973:Glutamine; D001120:Arginine