title: Supercapacitive admittance tomoscopy.
abstract: A sensor for measuring adsorption on a substrate has been designed including a contactless detection scheme, called supercapacitive admittance tomoscopy (SCAT). The sensor comprises a thin dielectric layer with two parallel band electrodes on the one side and a chemically modified surface on the other onto which the adsorption of molecules occurs. Upon application of a high frequency ac voltage between the two electrodes, a capacitive coupling is established across the dielectric layer, and the admittance measured depends on the surface state of the chemically modified interface. On the basis of this principle, a flow sensor has been developed to measure sensorgrams to follow the dynamics of the adsorption and has been tested for the adsorption of IgG on the modified surface.
authors.affiliation: Laboratoire d'Electrochimie Physique et Analytique, Ecole Polytechnique Fédérale de Lausanne, CH 1015 Lausanne, Switzerland.
authors.forename: Jean
authors.initials: J
authors.lastname: Gamby
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Abid
authors.forename: Hubert H
authors.initials: HH
authors.lastname: Girault
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D004867:Equipment Design; D007074:Immunoglobulin G / Q000737:chemistry; D011093:Polyethylene Terephthalates / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors; D014056:Tomography, X-Ray / Q000295:instrumentation* / Q000379:methods
chemical_list: D007074:Immunoglobulin G; D011093:Polyethylene Terephthalates