title: [Effects of different light-dark cycles on total and differential leukocyte counts as well as spontaneous locomotor activity in mice].
abstract: OBJECTIVE
  To investigate the effect of different light-dark cycles on total and differential counts of leukocyte as well as spontaneous locomotor activity in mice.
  
  
  METHODS
  144 ICR mice were raised under different light-dark cycles including LD 7 h/7 h, LD 12 h/12 h and LD 16 h/16 h for 8 weeks. Blood samples were obtained by enucleation of eye for total and differential counts of leukocyte. Another 9 mice were also divided into 3 groups and fed under same conditions as above. Their activities were recorded continuously.
  
  
  RESULTS
  The change of spontaneous locomotor activity and leukocyte count were synchronized with the light-dark cycle.
  
  
  CONCLUSIONS
  Different light-dark cycles can influence not only the spontaneous locomotor activity, but also total and differential leukocyte counts in mice.
authors.forename: Li
authors.initials: L
authors.lastname: Guo
authors.forename: Yan-you
authors.initials: YY
authors.lastname: Liu
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Zhou
authors.initials: Z
authors.lastname: Jiang
authors.forename: Yue-qi
authors.initials: YQ
authors.lastname: Wang
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Wang
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000528:radiation effects*; D003624:Darkness; D007958:Leukocyte Count; D007962:Leukocytes / Q000528:radiation effects*; D008027:Light; D051379:Mice; D008813:Mice, Inbred ICR; D009043:Motor Activity; D017440:Photoperiod