Irinotecan (CPT-11) combined with cisplatin for small cell carcinoma of the nasal cavity.
We describe a case of small cell carcinoma arising in the nasal cavity using combined chemotherapy with irinotecan (CPT-11)/cisplatin followed by surgical salvage which successfully avoided a radical operation. In a follow-up no local recurrence was observed over 3 years after the operation. Ours is the first report of the use of combined irinotecan (CPT-11)/cisplatin chemotherapy in small cell carcinoma of the nasal cavity.
Hakuba
Nobuhiro
N
Department of Otolaryngology, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun Ehime 791-0295, Japan. hakubax@m.ehime-u.ac.jp
Hyodo
Masamitsu
M
Yokoi
Takashi
T
Sato
Hidemitsu
H
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D000077146:Irinotecan; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D020360:Neoadjuvant Therapy; D009669:Nose Neoplasms / Q000188:drug therapy* / Q000601:surgery
D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin