[Relationship between liver mass and soluble intercellular adhesion molecule-1 in patients with liver cirrhosis].
OBJECTIVE
To investigate the relation of liver mass to, liver hymodynamics and soluble intercellular adhesion molecule-1 in patients with liver cirrhosis.


METHODS
The liver mass was measured by liver biopsy, hepatic hemodynamics by ultrasonography, and the contents of hyalurionic acid (HA), human procollagen III (HPC III) and collagen type IV (C IV) by radioimmunoassay in 100 patients with liver cirrhosis in compensation stage and 30 normal control subjects.


RESULTS
Greater liver mass was accompanied by more severe liver fibrosis and reduced liver blood flow. The contents of HA, HPC III and C IV were obvious higher in the patients than in the normal controls (P<0.05) and increased with the liver mass. The liver mass was positively related to serum liver fibrosis indices (r=0.5612, P<0.05).


CONCLUSIONS
Liver mass in patients with liver cirrhosis is related to hepatic hemodynamics, indices for liver fibrosis and liver pathology.
Li
Jian
J
Department of Function, Huizhou Central Hospital, Huizhou 516001, China.
Wen
Hong
H
Li
Sha-guang
SG
Yang
Qing-xu
QX
Yang
Li-fen
LF
Wu
Tong-tong
TT
Lai
Lin-xiu
LX
Lü
Han-wen
HW
D000368:Aged; D001775:Blood Circulation; D024061:Collagen Type III / Q000097:blood; D024141:Collagen Type IV / Q000097:blood; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000097:blood; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D008099:Liver / Q000098:blood supply / Q000473:pathology*; D008103:Liver Cirrhosis / Q000097:blood / Q000473:pathology*; D008297:Male; D008875:Middle Aged
D024061:Collagen Type III; D024141:Collagen Type IV; D018799:Intercellular Adhesion Molecule-1; D006820:Hyaluronic Acid