Determination of the spatial structure of glutathione by residual dipolar coupling analysis.
The approach based on analysis of the residual 1H-13C dipolar couplings in molecules partially aligned in a lyotropic liquid crystalline medium was used in the NMR investigation of the reduced glutathione (Glu-Cys-Gly; GSH) structure in a lyotropic medium (cetylpyridinium chloride-n-hexanol). The spatial structure of GSH in solution was established on the basis of the experimental data for observed couplings only.
Klochkov
Anton V
AV
Department of Physics, Kazan State University, Kremlevskaja ulitsa 18, 420008 Kazan, Russian Federation.
Khairutdinov
Bulat I
BI
Tagirov
Murat S
MS
Klochkov
Vladimir V
VV
D002247:Carbon Isotopes; D018360:Crystallography, X-Ray; D005978:Glutathione / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D008958:Models, Molecular; D011522:Protons; D012015:Reference Standards
D002247:Carbon Isotopes; D011522:Protons; D005978:Glutathione