title: Hemoglobin-based hydrogen peroxide biosensor tuned by the photovoltaic effect of nano titanium dioxide.
abstract: The photovoltaic effect of titanium dioxide (TiO2) nanoparticles, induced by ultraviolet light, can greatly improve the catalytic activity of hemoglobin as a peroxidase, with the sensitivity increased nearly 3-fold and the detection limit lowered 2 orders, in contrast to the catalytic reactions in the dark, which indicates a possible method to tune the properties of proteins for development of photocontrolled protein-based biosensors.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhou
authors.forename: Xin
authors.initials: X
authors.lastname: Gan
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhu
authors.forename: Genxi
authors.initials: G
authors.lastname: Li
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D002384:Catalysis; D002417:Cattle; D006454:Hemoglobins / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010777:Photochemistry; D014025:Titanium / Q000737:chemistry*
chemical_list: D006454:Hemoglobins; C009495:titanium dioxide; D006861:Hydrogen Peroxide; D014025:Titanium