title: [Evolution of antibiotic resistance and serogroups of Streptococcus pneumoniae over the 1997-2003 period in Brittany].
abstract: At this time, many antibiotics have decreased activity against Streptococcus pneumoniae, a major agent of infectious disease. In this study, we evaluated antibiotic susceptibility and serogroups of strains isolated from bacteraemia, meningitis and acute otitis media in adults and children over the 1997-2003 period in Brittany, France. In 2003, 62% of the isolates were not susceptible to penicillin and 11% were fully resistant. The prevalence of erythromycin resistance was 63%. Resistance rates were higher among isolates recovered from children than adults. Serogroups 19 and 14 were the most frequently isolated, especially the 19 one among children. The emergence of this serogroup might be a consequence of the use of heptavalent conjugate vaccine introduced in 2001 in France. Future surveillance after vaccination will be needed to detect emerging serogroups and resistance among S. pneumoniae.
authors.affiliation: Département de bactériologie-virologie et hygiène hospitalière, CHU, 35033 Rennes, France. sophie.mignard@chu-lyon.fr
authors.forename: S
authors.initials: S
authors.lastname: Mignard
authors.forename: P-Y
authors.initials: PY
authors.lastname: Donnio
authors.forename: J
authors.initials: J
authors.lastname: Vaucel
authors.forename: M-L
authors.initials: ML
authors.lastname: Abalain
authors.forename: M
authors.initials: M
authors.lastname: Anguill
authors.forename: J-P
authors.initials: JP
authors.lastname: Aubry
authors.forename: L
authors.initials: L
authors.lastname: Desbordes
authors.forename: M-J
authors.initials: MJ
authors.lastname: Dufour
authors.forename: J-Y
authors.initials: JY
authors.lastname: Esvant
authors.forename: F
authors.initials: F
authors.lastname: Gangneux
authors.forename: F
authors.initials: F
authors.lastname: Geffroy
authors.forename: A
authors.initials: A
authors.lastname: Gougeon
authors.forename: J-L
authors.initials: JL
authors.lastname: Laborie
authors.forename: C
authors.initials: C
authors.lastname: Lebrun
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authors.lastname: Le Gac
authors.forename: G
authors.initials: G
authors.lastname: Lelay
authors.forename: A-L
authors.initials: AL
authors.lastname: Lerestif-Gautier
authors.forename: A
authors.initials: A
authors.lastname: LeMeur
authors.forename: J
authors.initials: J
authors.lastname: Minet
authors.forename: O
authors.initials: O
authors.lastname: Morvan
authors.forename: P
authors.initials: P
authors.lastname: Plessis
authors.forename: P
authors.initials: P
authors.lastname: Pouedras
authors.forename: J
authors.initials: J
authors.lastname: Rome
authors.forename: D
authors.initials: D
authors.lastname: Tandé
authors.forename: A
authors.initials: A
authors.lastname: Valogne
authors.forename: C
authors.initials: C
authors.lastname: Voisine
authors.forename: J-F
authors.initials: JF
authors.lastname: Ygout
mesh_terms: D000328:Adult; D002648:Child; D024881:Drug Resistance, Bacterial; D005602:France; D006785:Hospitals, University; D006801:Humans; D010400:Penicillin G / Q000494:pharmacology; D012703:Serotyping; D013290:Streptococcal Infections / Q000188:drug therapy; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects*
chemical_list: D010400:Penicillin G