title: Pleuropulmonary infections caused by Mycobacterium bovis: a re-emerging disease.
abstract: Between 1980 and 2003, 13 patients (0.95% of all cases of tuberculosis) at a 600-bed university hospital in Madrid, Spain, were diagnosed with Mycobacterium bovis infection. All 13 cases occurred between 1994 and 1999; the mean age of the patients was 50 years (range 23-83 years), and 77% were males. Four (30%) patients were also positive for human immunodeficiency virus (HIV). The most frequent localisation of the disease was the lung (ten patients; 77%). Seven patients, including four HIV-positive patients who died, had multidrug-resistant M. bovis infection. No other patient died, including two HIV-negative patients with multidrug-resistant disease.
authors.affiliation: Division of Infectious Diseases and Department of Medical Microbiology, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Madrid, Spain. jesteban@fjd.es
authors.forename: J
authors.initials: J
authors.lastname: Esteban
authors.forename: P
authors.initials: P
authors.lastname: Robles
authors.forename: M
authors.initials: M
authors.lastname: Soledad Jiménez
authors.forename: M L
authors.initials: ML
authors.lastname: Fernández Guerrero
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000453:epidemiology*; D009163:Mycobacterium bovis; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*