title: [Spindle cell squamous carcinoma of the oral cavity: report of 2 cases].
abstract: Two cases with spindle cell squamous carcinoma were reported in this paper. The clinical, histopathologic features, therapy and prognosis were discussed. These tumors probably represented a heterogeneous group of squamous cell carcinoma whose components required either an identifiable squamous cell carcinoma or evidence of epithelial differentiation in the spindle cell. The clinical features were as follow: presents a male predominance among 60 to 70 years and site predilection for the low lip, tongue and gingiva, more aggressive and easy lymphatic metastases. Wide surgical excision, alone or with radical neck dissection was the most successful therapeutic modality. Local recurrence, lymphatic metastases and the depth of tumor invasion into underlying structures were found to be reliable prognostic indicators, the prognosis was dismal.
authors.affiliation: Department of Dentistry, Fifth People's Hospital, Wenzhou Medical College, Lishui Central Hospital, Lishui 323000, Zhejiang Province, China. Lsyewenc@lishui.gov.cn
authors.forename: Wen-cheng
authors.initials: WC
authors.lastname: Ye
authors.forename: Yuan
authors.initials: Y
authors.lastname: Huang
authors.forename: Wei-feng
authors.initials: WF
authors.lastname: Sun
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Yin
authors.initials: Y
authors.lastname: Li
mesh_terms: D002277:Carcinoma; D002294:Carcinoma, Squamous Cell; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009062:Mouth Neoplasms; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local; D011379:Prognosis