Biologically active compounds of fungal origin displaying antitumor activity.
This review describes biologically active natural products displaying antitumor activities derived from fruit bodies and cultured mycelium of macromycetes. Among these compounds the most important are: polisaccharides, phenols, terpenes and others. Polysaccharides produce their antitumor effects by activating different immune responses in the host. Other compounds are examples of cytotoxic and immunomodulating activities.
Sułkowska-Ziaja
Katarzyna
K
Jagiellonian University, Collegium Medicum, Department of Pharmaceutical Botany, 9 Medyczna Str, 30-688 Kraków, Poland.
Muszyńska
Bozena
B
Końska
Grazyna
G
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005658:Fungi / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure
D000970:Antineoplastic Agents; D001685:Biological Factors