title: Evaluation of an improved technique for automated center lumen line definition in cardiovascular image data.
abstract: The aim of the study was to evaluate a new method for automated definition of a center lumen line in vessels in cardiovascular image data. This method, called VAMPIRE, is based on improved detection of vessel-like structures. A multiobserver evaluation study was conducted involving 40 tracings in clinical CTA data of carotid arteries to compare VAMPIRE with an established technique. This comparison showed that VAMPIRE yields considerably more successful tracings and improved handling of stenosis, calcifications, multiple vessels, and nearby bone structures. We conclude that VAMPIRE is highly suitable for automated definition of center lumen lines in vessels in cardiovascular image data.
authors.affiliation: Department of Medical Informatics, Erasmus MC-University Medical Center Rotterdam, Dr. Molewaterplein 50, Room Ee 2167, 3015 GE, Rotterdam, The Netherlands.
authors.forename: Hugo A F
authors.initials: HA
authors.lastname: Gratama van Andel
authors.forename: Erik
authors.initials: E
authors.lastname: Meijering
authors.forename: Aad
authors.initials: A
authors.lastname: van der Lugt
authors.forename: Henri A
authors.initials: HA
authors.lastname: Vrooman
authors.forename: Cecile
authors.initials: C
authors.lastname: de Monyé
authors.forename: Rik
authors.initials: R
authors.lastname: Stokking
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000379:methods*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000000981:diagnostic imaging; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008432:Mathematical Computing; D015588:Observer Variation; D012680:Sensitivity and Specificity; D012984:Software; D036542:Tomography, Spiral Computed / Q000379:methods*