A de novo designed inhibitor of D-Ala-D-Ala ligase from E. coli.
Besong
Gilbert E
GE
School of Chemistry, University of Leeds, UK.
Bostock
Julieanne M
JM
Stubbings
Will
W
Chopra
Ian
I
Roper
David I
DI
Lloyd
Adrian J
AJ
Fishwick
Colin W G
CW
Johnson
A Peter
AP
D001665:Binding Sites; D018360:Crystallography, X-Ray; D003521:Cyclopropanes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000201:enzymology*; D008958:Models, Molecular; D008968:Molecular Conformation; D010453:Peptide Synthases / Q000037:antagonists & inhibitors*; D011487:Protein Conformation; D012984:Software; D013329:Structure-Activity Relationship
D003521:Cyclopropanes; D004791:Enzyme Inhibitors; C030797:cyclopropane; D010453:Peptide Synthases; C019638:D-alanylalanine synthetase