Nucleotide sequence of complementary DNA encoding for quaking protein of cow, horse and pig.
Complementary DNA (cDNA) for bovine quaking gene (Bqk), equine quaking gene (Eqk) and porcine quaking gene (Pqk), which are homologous to mouse quaking gene (qkI), were isolated, and their nucleotide sequences were determined. cDNA sequences of Bqk, Eqk and Pqk showed very high homology to that of qkI at nucleotide level; 94.2, 95.7 and 95.6%, respectively. Deduced amino acid sequences for Bqk, Eqk and Pqk perfectly matched to that of qkI. These findings suggest that the quaking gene family is highly conserved during mammalian evolution, and that Bqk, Eqk and Pqk are likely to have important biological functions also in cow, horse and pig.
Murata
Tomoaki
T
Yamaguchi University, Science Research Center, 1-1-1 Minamikogushi, Ube-city, Yamaguchi, 755-8505, Japan. ceb@yamaguchi-u.ac.jp
Yamashiro
Yasuhiro
Y
Kondo
Tatsuya
T
Nakaichi
Munekazu
M
Une
Satoshi
S
Taura
Yasuho
Y
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence / Q000235:genetics* / Q000502:physiology; D002417:Cattle / Q000235:genetics*; D017124:Conserved Sequence; D018076:DNA, Complementary; D005260:Female; D006736:Horses / Q000235:genetics*; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D016601:RNA-Binding Proteins / Q000235:genetics; D013552:Swine / Q000235:genetics*
D018076:DNA, Complementary; C098217:Qk protein, mouse; D016601:RNA-Binding Proteins