Cracking addiction the second time around: reconsolidation of drug-related memories.
One of the greatest challenges in the understanding and treatment of addiction is cue-elicited relapse to drug use. The present findings of Miller and Marshall and Lee et al. reported in this issue of Neuron demonstrate that retrieved drug-related memories undergo reconsolidation and thus suggest that these maladaptive associations may be more labile than previously thought.
Hernandez
Pepe J
PJ
Department of Psychiatry and Neuroscience Training Program, University of Wisconsin-Madison Medical School, 6001 Research Park Boulevard, Madison, Wisconsin 53719, USA.
Kelley
Ann E
AE
D000818:Animals; D016739:Behavior, Addictive / Q000523:psychology*; D003213:Conditioning, Psychological / Q000187:drug effects*; D016578:Crack Cocaine / Q000494:pharmacology*; D008568:Memory / Q000187:drug effects*
D016578:Crack Cocaine