title: New onset or exacerbation of psoriatic skin lesions in patients with definite rheumatoid arthritis receiving tumour necrosis factor alpha antagonists.
abstract: BACKGROUND
  Blockage of tumour necrosis factor alpha (TNFalpha) is highly effective in rheumatic diseases, especially in rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis. Furthermore, TNFalpha antagonists have also been shown to significantly reduce psoriatic skin lesions.
  
  
  METHODS
  A series of nine patients with RA who were treated with different types of TNFalpha antagonists and who unexpectedly developed either a new onset or an exacerbation of psoriatic skin lesions are reported.
authors.affiliation: Department of Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Schumannstr 20-21, 10117 Berlin, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Kary
authors.forename: M
authors.initials: M
authors.lastname: Worm
authors.forename: H
authors.initials: H
authors.lastname: Audring
authors.forename: D
authors.initials: D
authors.lastname: Huscher
authors.forename: M
authors.initials: M
authors.lastname: Renelt
authors.forename: H
authors.initials: H
authors.lastname: Sörensen
authors.forename: E
authors.initials: E
authors.lastname: Ständer
authors.forename: U
authors.initials: U
authors.lastname: Maass
authors.forename: H
authors.initials: H
authors.lastname: Lee
authors.forename: W
authors.initials: W
authors.lastname: Sterry
authors.forename: G-R
authors.initials: GR
authors.lastname: Burmester
mesh_terms: D000068879:Adalimumab; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000009:adverse effects; D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects; D000069285:Infliximab; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000139:chemically induced* / Q000473:pathology; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab; D000068879:Adalimumab; D000068800:Etanercept