Second trimester amniotic fluid endothelin concentration. A possible predictor for pre-eclampsia.
The mechanism of pre-eclampsia is still an enigma. There is now some evidence that amniotic concentrations of endothelin is elevated in pregnancies associated with pre-eclampsia. The aim of this prospective observational study was to record the concentration of amniotic fluid endothelin and compare this in women who develop pre-eclampsia and women who do not develop pre-eclampsia. Amniotic fluid concentration of endothelin is elevated by the second trimester in women who later develop pre-eclampsia.
Margarit
L
L
Department of Obstetrics and Gynaecology of the University Hospital of Patras, Greece. laviniamarg@yahoo.com
Griffiths
A
A
Tsapanos
V
V
Decavalas
G
G
Gumenos
D
D
D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry*; D001724:Birth Weight; D019332:Endothelin-1 / Q000032:analysis*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second
D019332:Endothelin-1