[The effect of chromatin remodeling and modification on RNA-polymerase-mediated transcription initiation].
As eukaryotes are characterized by the presence of chromatin (intricately packaged DNA), special mechanisms are required for preparing the DNA template for operation of the transcription machinery. Recently, a close association between the chromatin state and transcription was found and numerous transcription factors modifying the physical and chemical chromatin state were revealed. This review presents a brief description of transcription initiation on the DNA template within chromatin.
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D000818:Animals; D042002:Chromatin Assembly and Disassembly; D004247:DNA / Q000378:metabolism; D022041:Euchromatin / Q000378:metabolism*; D006570:Heterochromatin / Q000378:metabolism*; D012319:RNA Polymerase II / Q000378:metabolism*; D013698:Templates, Genetic; D014158:Transcription, Genetic
D022041:Euchromatin; D006570:Heterochromatin; D004247:DNA; D012319:RNA Polymerase II