title: Cells in the respiratory and intestinal tracts of chickens have different proportions of both human and avian influenza virus receptors.
abstract: Avian influenza viruses play a crucial role in the creation of human pandemic viruses. In this study, we have demonstrated that both human and avian influenza receptors exist in cells in the respiratory and intestinal tracts of chickens. We have also determined that primarily cultured chicken lung cells can support the replication of both avian and human influenza viruses.
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Republic of Korea.
authors.forename: Jin A
authors.initials: JA
authors.lastname: Kim
authors.forename: Si Yun
authors.initials: SY
authors.lastname: Ryu
authors.forename: Sang Heui
authors.initials: SH
authors.lastname: Seo
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002645:Chickens / Q000378:metabolism*; D003106:Colon / Q000378:metabolism* / Q000821:virology; D005434:Flow Cytometry; D006801:Humans; D009980:Influenza A virus / Q000378:metabolism* / Q000502:physiology; D008168:Lung / Q000378:metabolism* / Q000821:virology; D011991:Receptors, Virus / Q000096:biosynthesis* / Q000302:isolation & purification / Q000378:metabolism; D014779:Virus Replication / Q000502:physiology
chemical_list: D011991:Receptors, Virus