[Comparison of clonidine and tramadol added to prilocaine brachial plexus block - analgesia, sensory and motor block].
In a randomized, double-blind study we investigated the effect of clonidine and tramadol added to prilocaine on duration of analgesia, sensory and motor brachial plexus block. 60 patients were randomized in three groups. Group A received 40 ml prilocaine 1,5 % with tramadol 1,5 mg/kg KG, group B 40 ml prilocaine 1,5 % plus clonidine 1,5 microg/kg KG and group C 40 ml prilocaine 1,5 % without any additional medication. We recorded heart rate, blood pressure, oxygen saturation and sedation score at regular intervals. The onset of sensory and motor block was tested every five minutes for thirty minutes. The duration of analgesia, sensory and motor block were evaluated by using a questionnaire. There was no difference between the three groups concerning onset of brachial plexus block and duration of analgesia. But there was a significant prolongation of the duration of sensory and motor block in group B. Haemodynamic parameters remained stable in all patients, there were no significant changes in blood pressure and sedation.
Broch
O
O
Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel. broch@anaesthesie.uni-kiel.de
Breucking
E
E
D000316:Adrenergic alpha-Agonists; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D003000:Clonidine; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D019148:Neuromuscular Blockade; D010100:Oxygen / Q000097:blood; D010147:Pain Measurement; D011318:Prilocaine; D011795:Surveys and Questionnaires; D014147:Tramadol
D000316:Adrenergic alpha-Agonists; D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D011318:Prilocaine; D014147:Tramadol; D003000:Clonidine; D010100:Oxygen