title: A preliminary survey of Atopobium vaginae in women attending the Dunedin gynaecology out-patients clinic: is the contribution of the hard-to-culture microbiota overlooked in gynaecological disorders?
abstract: Preliminary studies have indicated that the recently described bacterium Atopobium vaginae may have an association with bacterial vaginosis (BV). Fifty-five women attending the gynaecology out-patient's clinic were tested for the presence of this micro-organism, Gardnerella vaginalis, Mobiluncus and Bacteroides species by polymerase chain reaction (PCR)-based assays. The frequency of detection was 40%. PCR detection of Gardnerella vaginalis with A. vaginae, occurred in 50% of A. vaginae-positive cases. Due to the high detection rate of A. vaginae we believe that it is important to determine whether this and other hard-to-culture microorganisms have a role in gynaecological disorders.
authors.affiliation: Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand. jeremy.burton@blis.co.nz
authors.forename: Jeremy P
authors.initials: JP
authors.lastname: Burton
authors.forename: Chris N
authors.initials: CN
authors.lastname: Chilcott
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Qumber
authors.forename: Heather J L
authors.initials: HJ
authors.lastname: Brooks
authors.forename: Don
authors.initials: D
authors.lastname: Wilson
authors.forename: John R
authors.initials: JR
authors.lastname: Tagg
authors.forename: Celia
authors.initials: C
authors.lastname: Devenish
mesh_terms: D039903:Actinobacteria / Q000145:classification* / Q000302:isolation & purification*; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000554:Ambulatory Care Facilities; D015331:Cohort Studies; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D009520:New Zealand / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D011379:Prognosis; D012720:Severity of Illness Index; D016585:Vaginosis, Bacterial / Q000175:diagnosis* / Q000453:epidemiology*
chemical_list: D004269:DNA, Bacterial