Simulation of the neuronal interactions and connection of neuronal activity with changes of heart rhythm and myocardial electrophysiological properties.
The purpose was to create the software for analysis of temporal relationship between spike trains of several neurons and connection of neuronal activity with changes of heart rhythm and some electrocardiogram parameters. The designed software represents an integrated estimation of the cross-correlograms and cardiac-cycle triggered correlograms combination. It permits the study of the nonrandom temporal relationship between spike trains of neurons using experimental data and the estimation of the roles of one neuron and a group of them and the role of their discharges patterns in changes of heart rhythm and electrophysiological properties of the myocardium.
Prudnikau
Heorhi A
HA
The Normal Physiology Department of The Belarussian State Medical University, Minsk, Belarus. pruge@narod.ru
D000200:Action Potentials / Q000502:physiology*; D000328:Adult; D003198:Computer Simulation; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009200:Myocardial Contraction / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D017711:Nonlinear Dynamics; D012984:Software