title: Total-body 3D magnetic resonance angiography influences the management of patients with peripheral arterial occlusive disease.
abstract: High-resolution total-body 3D MR angiography (MRA) has recently become available, revealing additional clinically relevant disease in patients with peripheral arterial occlusive disease (PAOD). However, the actual impact of total-body MRA on patient management in patients with PAOD has not been investigated so far. Two hundred forty-nine consecutive patients with angiographically proven PAOD were prospectively examined by means of contrast-enhanced total-body 3D MRA on a 1.5-T MR scanner. All correlative imaging studies performed within 60 days of total-body MRA were included in the efficacy analysis. Additional clinically relevant disease (luminal narrowing >50%, aneurysmal changes or dissections) was found in 73 segments (52 patients), including the renal arteries (36 segments), carotid arteries (28 segments), subclavian arteries (four segments) and abdominal aortic aneurysms (AAA) (five segments). Of the 73 segments, 36 were deemed necessary for further investigation by means of focused MRA examinations; the diagnosis was confirmed in all cases. Within the 60-day follow-up period, interventional or surgical therapy outside the peripheral arterial tree was performed in nine patients (11 segments), including carotid endatherectomy and renal artery angioplasty. The outlined total-body 3D MRA approach permits a comprehensive evaluation of the arterial system in patients with atherosclerosis and does indeed have an impact on patient management in patients with PAOD.
authors.affiliation: University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. goyen@uke.uni-hamburg.de
authors.forename: Mathias
authors.initials: M
authors.lastname: Goyen
authors.forename: Christoph U
authors.initials: CU
authors.lastname: Herborn
authors.forename: Knut
authors.initials: K
authors.lastname: Kröger
authors.forename: Stefan G
authors.initials: SG
authors.lastname: Ruehm
authors.forename: Jörg F
authors.initials: JF
authors.lastname: Debatin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000473:pathology* / Q000628:therapy; D003287:Contrast Media; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000473:pathology* / Q000628:therapy; D011446:Prospective Studies; D051598:Whole Body Imaging
chemical_list: D003287:Contrast Media