title: Risk of thromboembolism and bleeding after general surgery in patients with atrial fibrillation.
abstract: We provide insight into the risk of perioperative thromboembolism and bleeding in patients who have atrial fibrillation, use anticoagulants, and undergo a surgical procedure. Ninety-four patients underwent 121 noncardiac operations during a mean follow-up of 29 months. There was a 3.6-fold increased risk for all bleeding complications within 1 month after surgery compared with the control period (95% confidence interval 1.05 to 12.0). No thromboembolic event occurred in the first month after surgery compared with 11 events in the remaining period (0.4% per month).
authors.affiliation: Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. r.vink@amc.uva.nl
authors.forename: Roel
authors.initials: R
authors.lastname: Vink
authors.forename: Michiel
authors.initials: M
authors.lastname: Rienstra
authors.forename: Carlo J J
authors.initials: CJ
authors.lastname: van Dongen
authors.forename: Marcel
authors.initials: M
authors.lastname: Levi
authors.forename: Harry R
authors.initials: HR
authors.lastname: Büller
authors.forename: Harry J
authors.initials: HJ
authors.lastname: Crijns
authors.forename: Isabelle C
authors.initials: IC
authors.lastname: van Gelder
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000150:complications* / Q000188:drug therapy; D016063:Blood Loss, Surgical / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013923:Thromboembolism / Q000209:etiology* / Q000503:physiopathology; D013997:Time Factors
chemical_list: D000925:Anticoagulants