Four new compounds from the roots of Uvaria macrophylla.
Four new compounds, uvamalols A-C and uvarimacrophin A, have been isolated from the roots of Uvaria macrophylla. Their structures have been elucidated by spectroscopic methods. The relative configurations of uvamalols A-C have been established by NOE experiments, and the relative stereochemistry of uvarimacrophin A inferred from the diagnostic NMR data by comparison with known model compounds.
Wang
Si
S
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Zhang
Pei-Cheng
PC
Chen
Ruo-Yun
RY
Dai
Sheng-Jun
SJ
Yu
Shi-Shan
SS
Yu
De-Quan
DQ
D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D031046:Uvaria / Q000737:chemistry*
D001688:Biological Products