[Effect of Guliu capsule combined with 89Sr therapy on metastatic bone tumor].
OBJECTIVE
To evaluate the therapeutic effects of Guliu capsule (GLC) combined with 89Sr in treating metastatic bone tumors.


METHODS
On the basis of random sampling and grouping, 50 patients with metastatic bone tumors were selected to receive combined treatment with GLC and (89)Sr with another 50 patients recruited for (89)Sr treatment alone. The therapeutic effect of the therapies were evaluated according to the relief of ostalgia and quality-of life (QOF), local bone metabolism and hematopoietic function of the bone marrow.


RESULTS
The efficacy rate of GLC+89Sr and (89)Sr in relieving ostalgia was 94.0% and 76.0%, and the rate of QOF improvement and stabilization was 94.0% and 74.0%, respectively, both showing significant difference between the two groups (P<0.05). The effect of the two treatment protocols on local bone metabolism and their hemotoxicity were also significantly different (P<0.05, P<0.01, respectively).


CONCLUSIONS
Combined treatment with GLC and (89)Sr is effective for metastatic bone tumor and improves the patient's QOF with enhanced ostalgia relief rate and decreased hemotoxicity.
Su
Xu-chun
XC
Department of Integrated Traditional Chinese and Western Medicine, Guangzhou Tumor Hospital, Guangzhou 510095, China. sxc118@126.com
Wang
Yong-lin
YL
Yang
Xue-yan
XY
Liu
Cheng-lin
CL
Yan
Bin-chuan
BC
Kong
Jia-xin
JX
Song
Xian-lu
XL
Liang
Kun
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D002214:Capsules; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013326:Strontium Radioisotopes / Q000627:therapeutic use*
D002214:Capsules; D004365:Drugs, Chinese Herbal; D013326:Strontium Radioisotopes