title: [Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome].
abstract: OBJECTIVE
  To determine the effects of astragali injection on tubular and its possible mechanisms.
  
  
  METHODS
  Sixty patients with primary nephritic syndrome (PNS) were randomly divided into astragali group (n = 30) and control group (n = 30). The surm albumin (sALB) and urinary excretion of retinol-binding protein (RBP), N-Acety-P-beta-Glucosaminidase (NAG), beta2- Microglobulin (beta2MG) were measured before and after the treatment.
  
  
  RESULTS
  After the one month treatment, sALB was significantly higher, and ubeta2MG, uNAG, uRBP, and 24 huP were significantly lower in astragali group (P <0.01, P < 0.05).
  
  
  CONCLUSIONS
  Astragali injection on tubular plays a protective role in PNS.
authors.affiliation: Department of Nephrology, Xiangya Hospital, Central South University, Changsha, China. xyclp@medmail.com.cn
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Chen
authors.forename: Qiao-Ling
authors.initials: QL
authors.lastname: Zhou
authors.forename: Jing-Hua
authors.initials: JH
authors.lastname: Yang
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine; D000293:Adolescent; D000328:Adult; D027885:Astragalus propinquus; D002648:Child; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007267:Injections; D007677:Kidney Function Tests; D007684:Kidney Tubules / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D020011:Protective Agents / Q000008:administration & dosage; D012177:Retinol-Binding Proteins / Q000652:urine; D012709:Serum Albumin / Q000032:analysis; D001613:beta 2-Microglobulin / Q000652:urine
chemical_list: D004365:Drugs, Chinese Herbal; D020011:Protective Agents; D012177:Retinol-Binding Proteins; D012709:Serum Albumin; D001613:beta 2-Microglobulin; D000118:Acetylglucosaminidase