title: [Seasonal changes in serum level of eosinophil-derived neurotoxin, interleukin-18, and interferon-gamma in pollinosis patients].
abstract: Pollinosis is the most common disease in the world in people touched by atopy. The aim of the study was to evaluate seasonal changes in serum levels of EDN, IL-18, and IFN-gamma.
  
  
  METHODS
  Studies were carried out on a group of 30 patients suffering from pollinosis, sensitive to pollen of Ryegrass engl. Twenty healthy subject were considered as a control group. Blood samples were collected in June and December. The concentrations of above mentioned substances were evaluated using ELISA method.
  
  
  CONCLUSIONS
  In pollen season the significant increase in concentration of EDN, and IL-18, and no changes in serum concentration of IFN-gamma were found.
authors.affiliation: Klinika Alergologii i Chorób Wewnetrznych Akademii Medycznej w Białymstoku. siergiejko@csk.pl
authors.forename: Zenon
authors.initials: Z
authors.lastname: Siergiejko
authors.forename: Ewa
authors.initials: E
authors.lastname: Swiebocka
authors.forename: Jolanta
authors.initials: J
authors.lastname: Tobolczyk
authors.forename: Jerzy
authors.initials: J
authors.lastname: Hofman
mesh_terms: D016022:Case-Control Studies; D047208:Eosinophil-Derived Neurotoxin / Q000097:blood*; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood*; D020382:Interleukin-18 / Q000097:blood*; D008297:Male; D006255:Rhinitis, Allergic, Seasonal / Q000097:blood*; D012621:Seasons
chemical_list: D020382:Interleukin-18; D007371:Interferon-gamma; D047208:Eosinophil-Derived Neurotoxin