[Applications of optical imaging].
Optical imaging in the form of near infrared fluorescence and bioluminescence has proven useful for a wide range of applications in the field of molecular imaging. Both techniques provide a high sensitivity (in the nanomolar range), which is of particular importance for molecular imaging. Imaging with near infrared fluorescence is especially cost-effective and can be performed, in contrast to radioactivity-based methods, with fluorescence dyes that remain stable for months. The most important advantage of bioluminescence, in turn, is the lack of background signal. Although molecular imaging with these techniques is still in the experimental phase, an application of near infrared fluorescence is already foreseeable for the imaging of superficial structures.
Schellenberger
Eyk
E
Institut für Radiologie, Charité-Universitätsmedizin, Berlin. eyk.schellenberger@charite.de
D000818:Animals; D017209:Apoptosis; D003952:Diagnostic Imaging; D007259:Infrared Rays; D008156:Luciferases; D008163:Luminescent Measurements; D023421:Models, Animal; D008958:Models, Molecular; D009369:Neoplasms / Q000473:pathology / Q000628:therapy; D019047:Phantoms, Imaging; D051381:Rats
D008156:Luciferases