Expression of a novel Ski-like gene in Xenopus development.
Members of the Ski/Sno family of gene products contain a characteristic peptide domain involved in protein-protein or protein-DNA interaction. Here, we characterize the developmental expression of xDawg, in Xenopus laevis, of a new gene, related to the Ski/Sno family of transcription regulators. The Ski/Sno domain of xDawg is predicted to present an electropositive surface, consistent with a role in DNA binding. This gene is expressed in the marginal zone of early gastrulae, and in the brain, sensory vesicles, and cranial neural crest of neurula and tailbud embryos.
Seufert
Daniel W
DW
Center for Molecular and Human Genetics, Columbus Children's Research Institute, 700 Children's Dr., Columbus, OH 43026, USA.
Hegde
Rashmi S
RS
Nekkalapudi
Srivamsi
S
Kelly
Lisa E
LE
El-Hodiri
Heithem M
HM
D000595:Amino Acid Sequence; D000818:Animals; D004625:Embryo, Nonmammalian / Q000737:chemistry / Q000378:metabolism; D015870:Gene Expression; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D012261:Ribonucleoproteins / Q000032:analysis / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics*; D029867:Xenopus Proteins / Q000235:genetics*; D014982:Xenopus laevis / Q000196:embryology* / Q000235:genetics
C511874:Dawg protein, Xenopus; D012261:Ribonucleoproteins; D014157:Transcription Factors; D029867:Xenopus Proteins; C026452:messenger ribonucleoprotein