Serum gastrin in canine chronic lymphocytic-plasmacytic enteritis.
This study evaluates serum gastrin concentrations in dogs with chronic lymphocytic-plasmacytic enteritis, as well as its possible relationship with the severity of lesions present in the stomach. To achieve this aim, 5 dogs without gastrointestinal disease and 15 dogs with chronic lymphocytic-plasmacytic enteritis were included. Serum gastrin concentrations were significantly increased in dogs with chronic lymphocytic-plasmacytic enteritis compared with those in dogs without gastrointestinal disease. Also, there was a positive correlation between the severity of the gastric lesion and the serum gastrin concentration. Our findings indicate the possibility that gastrin plays a role in the etiology of an accompanying chronic antral gastritis in canine chronic lymphocytic-plasmacytic enteritis.
García-Sancho
Mercedes
M
Department of Animal Medicine and Surgery, Veterinary Medicine Teaching Hospital, Faculty of Veterinary Medicine, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain. mercgarc@vet.ucm.es
Rodríguez-Franco
Fernando
F
Sainz
Angel
A
Rodríguez
Antonio
A
Silván
Gema
G
Illera
Juan Carlos
JC
D000704:Analysis of Variance; D000818:Animals; D016022:Case-Control Studies; D002908:Chronic Disease; D004283:Dog Diseases / Q000097:blood* / Q000473:pathology; D004285:Dogs; D004751:Enteritis / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D005260:Female; D005755:Gastrins / Q000097:blood*; D008297:Male; D012720:Severity of Illness Index; D013270:Stomach / Q000473:pathology
D005755:Gastrins