title: Genetic diversity of BVDV: consequences for classification and molecular epidemiology.
abstract: Genetic typing of bovine viral diarrhoea virus (BVDV) is important for the precise classification of viruses as well as for the development of molecular epidemiology. BVDV isolates were usually typed based on comparison of genomic sequences from the 5'-untranslated region (5'-UTR), N(pro) and E2 region. Recently we have identified 11 genetic groups (subgenotypes) of BVDV-1. Our further experiments confirmed a new subgenotype, BVDV-1k, isolated from cattle in Switzerland. BVDV isolates from India were typed as BVDV-1b whereas BVDV-1c is a predominant subgenotype in Australia. The results of genetic typing of BVDV indicate that distribution of subgenotypes has no relationship to the geographic origin of viral isolates.
authors.affiliation: University of Veterinary Medicine, Department of Infectious Diseases and Parasitology, Komenskeho 73, 041 81 Kosice, Slovakia. vilcek@uvm.sk
authors.forename: S
authors.initials: S
authors.lastname: Vilcek
authors.forename: B
authors.initials: B
authors.lastname: Durkovic
authors.forename: M
authors.initials: M
authors.lastname: Kolesarova
authors.forename: D J
authors.initials: DJ
authors.lastname: Paton
mesh_terms: D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000453:epidemiology* / Q000821:virology*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000145:classification* / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D005838:Genotype; D017720:Molecular Epidemiology