Leiomyomatous hamartoma presenting as a congenital epulis.
An otherwise-healthy 11-month-old white girl presented with a polyp-like lesion on the anteromedial part of the maxillary alveolar ridge. It looked like a congenital epulis, but histological examination showed fascicles of smooth muscle cells dispersed in collagenous stroma with a few peripheral nerve bundles that were intermingled with smooth muscle fibres. The muscle cells stained strongly for desmin and alpha-smooth-muscle actin. However, S-100 was found only in peripheral nerve bundles. It was therefore a leiomyomatous hamartoma.
Kujan
Omar
O
Unit of Oral Pathology, School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK.
Clark
Stuart
S
Sloan
Philip
P
D000199:Actins / Q000032:analysis; D003094:Collagen; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005882:Gingival Diseases / Q000151:congenital* / Q000175:diagnosis; D005887:Gingival Neoplasms / Q000151:congenital* / Q000175:diagnosis; D006222:Hamartoma / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D032389:Myocytes, Smooth Muscle / Q000473:pathology
D000199:Actins; D003893:Desmin; D003094:Collagen