Coexistence of pemphigus vulgaris and bullous pemphigoid in the upper aerodigestive tract.
Pemphigus vulgaris and bullous pemphigoid are autoimmune blistering diseases of the skin and the mucosa characterized by circulating autoantibodies. Coexistence of these lesions is extremely uncommon. We report herein a case of both pemphigus vulgaris and bullous pemphigoid which occurred in the upper aerodigestive tract. The diagnosis was made based on the circulating autoantibodies and direct immunofluorescent studies. The literature on this subject is reviewed.
Tabuchi
Keiji
K
Department of Otolaryngology, Doctorial Program in Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan. ktabuchi@md.tsukuba.ac.jp
Nomura
Masatake
M
Murashita
Hidekazu
H
Fujisawa
Yasuhiro
Y
Tsuji
Shigeki
S
Okubo
Hideki
H
Hara
Akira
A
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D051184:Desmoglein 3 / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D004947:Esophagus; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007830:Larynx; D008297:Male; D010391:Pemphigoid, Bullous / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D010392:Pemphigus / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D010614:Pharynx
D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D051184:Desmoglein 3; D007074:Immunoglobulin G