Phosphoproteomics: new insights into cellular signaling.
Developments in the field of phosphoproteomics have been fueled by the need simultaneously to monitor many different phosphoproteins within the signaling networks that coordinate responses to changes in the cellular environment. This article presents a brief review of phosphoproteomics with an emphasis on the biological insights that have been derived so far.
Mumby
Marc
M
Department of Pharmacology and the Alliance for Cellular Signaling, University of Texas Southwestern Medical Center, Dallas, TX 75390-9041, USA. marc.mumby@utsouthwestern.edu
Brekken
Deirdre
D
D006801:Humans; D007553:Isotope Labeling; D013058:Mass Spectrometry; D010748:Phosphopeptides / Q000737:chemistry; D010750:Phosphoproteins / Q000737:chemistry* / Q000378:metabolism*; D040901:Proteomics; D015398:Signal Transduction
D010748:Phosphopeptides; D010750:Phosphoproteins