title: Metagenomics-based drug discovery and marine microbial diversity.
abstract: As the global threat of drug-resistant pathogens continues to rise, new strategies and resources are required to accelerate and advance the drug discovery process. We believe that rapid progress in metagenomics has opened up a new era in the study of marine microbial diversity that enables direct access to the genomes of numerous uncultivable microorganisms. This review outlines recent developments and future trends in metagenomics-based drug discovery in marine microbial communities and their associated chemical prosperity.
authors.affiliation: South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, China 510301. lixiang@scsio.ac.cn
authors.forename: Xiang
authors.initials: X
authors.lastname: Li
authors.forename: Ling
authors.initials: L
authors.lastname: Qin
mesh_terms: D002874:Chromosome Mapping / Q000379:methods*; D015195:Drug Design; D014644:Genetic Variation / Q000235:genetics; D005827:Genetics, Microbial / Q000379:methods / Q000639:trends; D023281:Genomics / Q000379:methods*; D008386:Marine Biology / Q000379:methods* / Q000639:trends*; D004364:Pharmaceutical Preparations; D014871:Water Microbiology
chemical_list: D004364:Pharmaceutical Preparations