A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry.
A mild heterogeneous, ligand-free protocol for Sonogashira and Heck couplings has been developed and used to access several biologically important deoxynucleoside derivatives in a facile manner.
Garg
Neil K
NK
Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 164-30, Pasadena, CA 91125, USA.
Woodroofe
Carolyn C
CC
Lacenere
Christopher J
CJ
Quake
Stephen R
SR
Stoltz
Brian M
BM
D002384:Catalysis; D008670:Metals / Q000737:chemistry; D009705:Nucleosides / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D014529:Uridine / Q000138:chemical synthesis
D008670:Metals; D009705:Nucleosides; D010165:Palladium; D014529:Uridine