Early and late outcome after coronary artery bypass surgery in diabetic patients.
OBJECTIVE
To determine the impact of diabetes on outcome after coronary artery bypass surgery.


METHODS
We matched 866 diabetic patients with non-diabetic controls in regards to gender, age, left ventricular ejection fraction, body mass index, presence of unstable angina and history of myocardial infarction, and day of surgery. The 30-d mortality and morbidity were evaluated with univariate analysis and survival and freedom from cardiac death were assessed with the Kaplan-Meier method.


RESULTS
Follow-up time was 69+/-37 months. The 30-d mortality was 2.0% in the diabetic group and 1.0% in the non-diabetic group (p=0.15). Postoperative morbidity did not differ between groups. Cumulative 5- and 10-year survival rates were 89 and 71% in diabetics and 94 and 84% in non-diabetics (p=0.001). During follow-up, there was no difference between groups in regards to repeat revascularization.


CONCLUSIONS
The 30-d mortality was equally low in diabetic and non-diabetic patients with severe coronary artery disease. However, long-term survival was significantly lower in the diabetic group than in the non-diabetic group.
Hakala
Tapio
T
Department of Surgery and Anaesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, Finland. tapio.hakala@kuh.fi
Pitkänen
Otto
O
Halonen
Pirjo
P
Mustonen
Juha
J
Turpeinen
Anu
A
Hippelainen
Mikko
M
D016022:Case-Control Studies; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality; D003920:Diabetes Mellitus / Q000503:physiopathology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome