Amblyopia: a neuro-ophthalmic view.
Amblyopia designates monocular or binocular visual loss associated with form deprivation caused by obstruction or deformation of a light stimulus, strabismus, or uncorrected refractive error. Elegant neuroscientific studies have identified a critical period early in life in which the visual system is vulnerable to amblyopia and the site of pathology as the primary visual cortex. However, recent observations have challenged these concepts. A broader understanding of the pathophysiology of amblyopia will be critical to refining therapy for this condition.
Hoyt
Creig S
CS
Department of Opthalmology, University of California, San Francisco, CA 94143-0730, USA. cshoyt@itsa.ucsf.edu
D000550:Amblyopia / Q000503:physiopathology / Q000628:therapy; D006801:Humans