Two new dammarane triterpenoids from Kageneckia angustifolia D. Don.
Two new dammarane triterpenoids, 20R,21-epoxydammar-24-ene-3,23-dione and 20R,21-epoxy-3beta-hydroxydammar-24-ene-23-one have been isolated from the aerial parts of Kageneckia angustifolia D. Don, Rosaceae, along with the previously reported triterpenoids oleanolic acid and 3beta-(beta-D-glucosyloxy)-16alpha,23alpha-epoxycucurbita-5,24-dien-11-one and the phenolic prunasin. The structures of these compounds were established by MS, 1D- and 2D-NMR experiments, and the structure of the new compounds were confirmed by X-ray diffraction analysis.
López-Pérez
José Luis
JL
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Salamanca, E-37007 Salamanca, Spain. lopez@usal.es
Erazo
Silvia
S
Delporte
Carla
C
Negrete
Rosa
R
Muñoz
Orlando
O
García
Rubén
R
Backhouse
Nadine
N
San Feliciano
Arturo
A
D002247:Carbon Isotopes; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D008958:Models, Molecular; D008968:Molecular Conformation; D011522:Protons; D012015:Reference Standards; D027824:Rosaceae / Q000737:chemistry*; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D000097669:Dammaranes
D002247:Carbon Isotopes; D011522:Protons; D014315:Triterpenes; D000097669:Dammaranes; C507893:20,21-epoxy-3-hydroxydammar-24-ene-23-one; C507892:20,21-epoxydammar-24-ene-3,23-dione