title: [Role of hormones in volume regulating kidney function in patients with hypertension].
abstract: Improper functioning of kidneys plays a significant part in the development and further worsening of hypertension. The author aimed at studying the functional and hormonal activity of kidneys in patients with I-III stage essential hypertension under physiological hyperhydratation. 68 patients with essential hypertension and 21 patients of a control group have been observed. The blood content of hormones was detected before and after the physiological water stress consisting 2% of body weight. They are the following: rennin, angiotensin, aldosterone, vasopressin, and atrial sodium-releasing hormone. The observed patients with I stage essential hypertension mostly have their kidneys' ducts apparatus reconstructed with considerable decrease in water reabsorption in ducts apparatus of kidneys. It came along with high level of sodium excretion and moderate activation of rennin-angiotenstin-aldosterone system. Patients with II and III stage essential hypertension responds to the physiological water stress (in contrast to patients with I stage essential hypertension and patients of the control group) with progressive increase in water reabsorption in ducts apparatus of kidneys, decrease in sodium excretion comes along with high level of aldosterone, vasopressin and atrial sodium-releasing hormones.
authors.forename: I A
authors.initials: IA
authors.lastname: Plesh
mesh_terms: D000450:Aldosterone / Q000378:metabolism; D009320:Atrial Natriuretic Factor / Q000378:metabolism; D004231:Diuresis / Q000502:physiology*; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism / Q000503:physiopathology*; D007668:Kidney / Q000378:metabolism / Q000503:physiopathology*; D007677:Kidney Function Tests; D008875:Middle Aged; D012083:Renin / Q000378:metabolism; D014667:Vasopressins / Q000378:metabolism
chemical_list: D006728:Hormones; D014667:Vasopressins; D000450:Aldosterone; D009320:Atrial Natriuretic Factor; D012083:Renin