title: Common receptor for Bacillus thuringiensis toxins Cry1Ac, Cry1Fa, and Cry1Ja in Helicoverpa armigera, Helicoverpa zea, and Spodoptera exigua.
abstract: Binding studies using (125)I-Cry1Ac and biotinylated Cry1Fa toxins indicate the occurrence of a common receptor for Cry1Ac, Cry1Fa, and Cry1Ja in Helicoverpa armigera, Helicoverpa zea, and Spodoptera exigua. Our results, along with previous binding data and the observed cases of cross-resistance, suggest that this pattern seems to be widespread among lepidopteran species.
authors.affiliation: Departament de Genètica, Universitat de València, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain.
authors.forename: Carmen Sara
authors.initials: CS
authors.lastname: Hernández
authors.forename: Juan
authors.initials: J
authors.lastname: Ferré
mesh_terms: D000818:Animals; D001413:Bacillus thuringiensis / Q000378:metabolism* / Q000472:pathogenicity; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000378:metabolism*; D001427:Bacterial Toxins / Q000378:metabolism*; D001665:Binding Sites; D001667:Binding, Competitive; D004731:Endotoxins / Q000378:metabolism*; D006460:Hemolysin Proteins; D019476:Insect Proteins / Q000378:metabolism*; D007915:Lepidoptera / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*; D018411:Spodoptera / Q000378:metabolism*
chemical_list: D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D001427:Bacterial Toxins; C095416:Cry toxin receptors; D004731:Endotoxins; D006460:Hemolysin Proteins; D019476:Insect Proteins; D011956:Receptors, Cell Surface; C030956:insecticidal crystal protein, Bacillus Thuringiensis