title: Two cases of feline malignant craniopharyngioma.
abstract: Tumors at the cranial base in 2 cats (a 9 1/2-year-old, castrated male Chinchilla and a 7-year-old, castrated male American Shorthair) were diagnosed as malignant craniopharyngioma. The tumor lesion was histopathologically divided into four parts: 1) a small acinus part, in which relatively large cells with a pale cytoplasm composed small acini; 2) a duct part, in which small cuboidal cells composed ducts; 3) a cyst part, in which there were large cysts lined with flat cells; and 4) a pavement part, in which large multi-angular-shaped cells proliferated in a pavement pattern. The epithelial cells of some parts were positive for keratin by immunohistochemistry. Histopathologic findings of the present feline cases were identical to those of malignant craniopharyngioma in other animal species.
authors.affiliation: Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, 1-1-1 Yayoi, Bunkyoku, Tokyo 113-8657, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nagata
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Uetsuka
authors.forename: A
authors.initials: A
authors.lastname: Yasoshima
authors.forename: S
authors.initials: S
authors.lastname: Yasunaga
authors.forename: K
authors.initials: K
authors.lastname: Masuda
authors.forename: H
authors.initials: H
authors.lastname: Tsujimoto
authors.forename: E
authors.initials: E
authors.lastname: Kuwajima
authors.forename: R
authors.initials: R
authors.lastname: Nishimura
authors.forename: N
authors.initials: N
authors.lastname: Sasaki
authors.forename: K
authors.initials: K
authors.lastname: Doi
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000473:pathology*; D002415:Cats; D003397:Craniopharyngioma / Q000175:diagnosis / Q000473:pathology* / Q000662:veterinary*; D008297:Male