title: Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis.
abstract: Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.
authors.affiliation: Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas-Houston Medical School, 77030, USA.
authors.forename: Annie
authors.initials: A
authors.lastname: Philip
authors.forename: Zekaver
authors.initials: Z
authors.lastname: Odabasi
authors.forename: Gloria
authors.initials: G
authors.lastname: Matiuzzi
authors.forename: Victor L
authors.initials: VL
authors.lastname: Paetznick
authors.forename: Sze-Wee
authors.initials: SW
authors.lastname: Tan
authors.forename: John
authors.initials: J
authors.lastname: Warmington
authors.forename: John H
authors.initials: JH
authors.lastname: Rex
authors.forename: Luis
authors.initials: L
authors.lastname: Ostrosky-Zeichner
mesh_terms: D000908:Antibodies, Fungal / Q000097:blood*; D000946:Antigens, Fungal / Q000276:immunology; D002175:Candida / Q000145:classification / Q000276:immunology*; D002177:Candidiasis / Q000175:diagnosis* / Q000382:microbiology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D016469:Fungemia / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007121:Immunocompetence; D016867:Immunocompromised Host; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
chemical_list: D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D011933:Reagent Kits, Diagnostic