title: Statistical criteria to establish bioassay programs.
abstract: A statistical study of fitting log-normal distributions to air sampling concentrations and random intakes is reported in this paper. An improved method on the approximation of a sum of log-normal distributions to a log-normal distribution is used to forecast bioassay results and their uncertainties. These methods can be used in the design and implementation of air control monitoring and bioassay programs for introducing statistical criteria to determine when a bioassay is required as well as the frequency.
authors.affiliation: Department of Statistics, University of Salamanca, Spain. fidalgo@usal.es
authors.forename: Jesus
authors.initials: J
authors.lastname: Lopez-Fidalgo
authors.forename: Guillermo
authors.initials: G
authors.lastname: Sanchez
mesh_terms: D000396:Air Pollutants, Radioactive / Q000032:analysis* / Q000493:pharmacokinetics*; D000465:Algorithms; D001681:Biological Assay / Q000379:methods*; D001822:Body Burden; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D008954:Models, Biological; D016273:Occupational Exposure / Q000032:analysis; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods*; D011835:Radiation Protection / Q000379:methods*; D011868:Radioisotopes / Q000032:analysis* / Q000493:pharmacokinetics*; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D018401:Sample Size
chemical_list: D000396:Air Pollutants, Radioactive; D011868:Radioisotopes