title: Determination of carbamate insecticides in Chinese medicinal herbs by gas chromatography with a nitrogen-phosphorus detector.
abstract: A simplified method for determining carbamate insecticides (including metolcarb, isoprocarb, fenobucarb, carbofuran, pirimicarb, and carbaryl) in Chinese medicinal herbs (White Peony Alba, Red Peony Root, and Baical Skullcap Root) is described. Standards were fortified into Chinese medicinal herbs at 3 levels (0.05-0.5 mg/kg). The carbamates were extracted with dichloromethane in a Soxhlet apparatus and analyzed by gas chromatography with a nitrogen-phosphorus detector. The results showed average recoveries between 80.77 and 104.56%. The method evidenced good robustness, accuracy, and precision for monitoring carbamates in Chinese medicinal herb samples, and it is a suitable alternative to replace the currently dedicated analytical systems. The minimum detectable amount ranged from 3.0 x 10(-10) to 5.0 x 10(-10)g, and the limit of quantification was 0.05 mg/kg. The method is rapid, simple, sensitive, and reproducible, and it can be conveniently used as a low-cost, rapid method for measuring the carbamate insecticide contamination of Chinese medicinal herbs.
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Huajiachi Campus, Hangzhou, Zhejiang, People's Republic of China, 310029. jlwu@zju.edu.cn
authors.forename: Jialun
authors.initials: J
authors.lastname: Wu
authors.forename: Liqing
authors.initials: L
authors.lastname: Li
authors.forename: Yaohua
authors.initials: Y
authors.lastname: Zou
mesh_terms: D002219:Carbamates / Q000032:analysis*; D012721:Carbaryl / Q000032:analysis; D002235:Carbofuran / Q000032:analysis; D002849:Chromatography, Gas / Q000379:methods*; D004365:Drugs, Chinese Herbal; D007306:Insecticides / Q000378:metabolism / Q000494:pharmacology*; D009584:Nitrogen / Q000032:analysis*; D010573:Pesticide Residues; D010758:Phosphorus / Q000032:analysis*; D010936:Plant Extracts / Q000032:analysis; D011743:Pyrimidines / Q000032:analysis; D015203:Reproducibility of Results; D012989:Soil Pollutants; D013997:Time Factors; D014873:Water Pollutants
chemical_list: D002219:Carbamates; D004365:Drugs, Chinese Herbal; D007306:Insecticides; D010573:Pesticide Residues; D010936:Plant Extracts; D011743:Pyrimidines; D012989:Soil Pollutants; D014873:Water Pollutants; C011994:pirimicarb; D010758:Phosphorus; C019276:BPMC; C065256:isoprocarb; D009584:Nitrogen; D012721:Carbaryl; D002235:Carbofuran