Intercellular adhesion molecule-1 concentration, in utero, decreases after antibiotic treatment.
A parturient suffering from preterm premature rupture of membranes at 29-weeks of gestation was hospitalized and staphylococcus was detected in her amniotic fluid. After treatment with antibiotics she delivered a healthy neonate three weeks later. ICAM-1 levels decreased by 20 fold correlating with elimination of the bacteria and prolongation of the pregnancy.
Hadar
Amnon
A
Department of Obstetrics & Gynecology A, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel.
Shani-Shrem
Noa
N
Horowitz
Shulamith
S
D000328:Adult; D000653:Amniotic Fluid / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D011263:Pregnancy Trimester, Third; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D018799:Intercellular Adhesion Molecule-1