title: Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia.
abstract: We report the results of unrelated cord blood transplantation (CBT) in a 12-year-old boy with Philadelphia chromosome- positive chronic myelogenous leukemia in the chronic phase and a high body weight (68.5 kg at transplantation). Only 1 of the 2 units used engrafted. This unit was not human leukocyte antigen (HLA) class II identical with the patient and had a much larger number of nucleated cells than the other unit (approximately 2.4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan.
authors.affiliation: Department of Pediatrics, Taipei Veterans General Hospital, Taiwan.
authors.forename: Giun-Yi
authors.initials: GY
authors.lastname: Hung
authors.forename: Tzeon-Jye
authors.initials: TJ
authors.lastname: Chiou
authors.forename: Chia-Yau
authors.initials: CY
authors.lastname: Chang
authors.forename: Hao-Wei
authors.initials: HW
authors.lastname: Teng
authors.forename: Po-Min
authors.initials: PM
authors.lastname: Chen
authors.forename: Betau
authors.initials: B
authors.lastname: Hwanga
mesh_terms: D002648:Child; D036101:Cord Blood Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000628:therapy*; D008297:Male