Emerging applications of phosphorescent metalloporphyrins.
The subject of phosphorescent metalloporphyrins is reviewed, focusing mainly on the development and application of Pt- and Pd-porphyrins. A summary of their general chemical and photophysical properties, and guidelines for rational design of the phosphorescent labels, bioconjugates and probes is given. Examples of different detection formats and particular bio-analytical applications developed in recent years are presented. The potential of phosphorescent porphyrin label methodology is discussed and compared to that of the long-decay fluorescent lanthanide chelates and other common fluorophores.
Papkovsky
Dmitri B
DB
Biochemistry Department/ABCRF, University College Cork, College Road, Cork, Ireland. d.papokovsky@ucc.ie
O'Riordan
Tomás C
TC
D001681:Biological Assay; D049449:Luminescence; D049408:Luminescent Agents / Q000737:chemistry*; D008163:Luminescent Measurements; D008665:Metalloporphyrins / Q000737:chemistry*
D049408:Luminescent Agents; D008665:Metalloporphyrins