title: [Comparing the actions of the three flavone ingredients in choerospondias axillaris on arrhythmias induced by aconitine].
abstract: OBJECTIVE
  To compare the actions of the three flavone ingredients in choerospondias axillaris on arrhythmias Induced by aconitine.
  
  
  METHODS
  Langendorff perfuse was applied in the experiment, the antiarrhythmic action was to study by using aconitine on the the isolated heart; The antiarrhythmic action of the three flavone ingredients in choerospondias axillaris was to study by using i.v. aconitine in rat to induce arrhythmias.
  
  
  RESULTS
  Compared with the NS group, sample 1 and sample 2 both significantly prolonged the beginning time of VF of isolated heart and increased the dosage of aconitine, sample 3 reduced the beginning time of VF of isolated heart and decreased the dosage of aconitine, sample 1 and sample 2 both greatly prolonged the beginning time of VE, VT, VF, HA; sample 3 greatly reduced the beginning time of VT,VF. The actions of the three samples were in a concentration-dependent way.
  
  
  CONCLUSIONS
  Sample 1 and sample 2 both resisted the occurrence of arrhythmias induced by aconitine, sample 3 markedly promoted the occurrence of arrhythmias induced by aconitine.
authors.affiliation: The Third Affiliated Hospital of Inner Mongolia Medical College, Baotou 014010, China.
authors.forename: Feng-Hua
authors.initials: FH
authors.lastname: Wang
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Yang
authors.forename: Ji-Hui
authors.initials: JH
authors.lastname: Xu
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Qin
authors.forename: Kang
authors.initials: K
authors.lastname: Ying
authors.forename: Chang-Zai
authors.initials: CZ
authors.lastname: Zhang
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Song
authors.forename: Teng-Fei
authors.initials: TF
authors.lastname: Yu
mesh_terms: D000157:Aconitine; D027926:Anacardiaceae / Q000737:chemistry; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000517:prevention & control*; D004305:Dose-Response Relationship, Drug; D005260:Female; D047309:Flavones / Q000302:isolation & purification / Q000627:therapeutic use*; D066298:In Vitro Techniques; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000889:Anti-Arrhythmia Agents; D047309:Flavones; D000157:Aconitine