Stroke in two children with Mycoplasma pneumoniae infection. A causal or casual relationship?
We report on 2 children who had a stroke biologically related to Mycoplasma pneumoniae infection. Invasion of the central nervous system and an immune mechanism represent 2 pathogenesis pathways. Prompt macrolide therapy does not prevent stroke, but immediate and aggressive immunosuppressive treatment seems to help recovery.
Leonardi
Salvatore
S
Paediatric Department, University of Catania, Catania, Italy. leonardi@unict.it
Pavone
Piero
P
Rotolo
Novella
N
La Rosa
Mario
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D008297:Male; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents