[Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report].
An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstrable. However, on account of the initial normal laboratory test of emostases, the partial correction of the prothrombin time with 50% normal plasma in vitro and the family history, the congenital deficiency in factor VII was ruled out. Whatever the mechanism involved, this factor VII deficiency was related to malignancy.
Zili
Mohamed
M
Laboratoire général Hôpital A. Mami Ariana.
Hammami
Sadok
S
Marghli
Adel
A
Mechmech
Lamia
L
Boughnim
Louisa
L
Abid
Salem
S
Brahim
N'siri
N
Toumi
Nour El Houda
Nel H
Kilani
Tarek
T
Yaalaoui
Sadok
S
D005168:Factor VII Deficiency / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged