Contrast-enhanced dark lumen PET/CT and MR colonography in a rodent polyp model: initial results with histopathologic correlation.
OBJECTIVE
The objective of this study was to assess the feasibility of PET/CT for the detection of colorectal masses in a rodent polyp model in an intraindividual comparison with dark-lumen MR colonography.


CONCLUSIONS
Detection of small tumors with PET/CT and MR colonography is possible in a rodent model. The technique thus warrants further evaluation in animal studies as well as in patients with suspected colorectal disease.
Kuehle
Christiane A
CA
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Veit
Patrick
P
Antoch
Gerald
G
Grabellus
Florian
F
Robert
Philippe
P
Beyer
Thomas
T
Herborn
Christoph U
CU
D000818:Animals; D003111:Colonic Polyps / Q000175:diagnosis* / Q000473:pathology; D023881:Colonography, Computed Tomographic; D003287:Contrast Media; D004195:Disease Models, Animal; D005240:Feasibility Studies; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014055:Tomography, Emission-Computed
D003287:Contrast Media