title: Efficacy of an inactivated feline panleucopenia virus vaccine against a canine parvovirus isolated from a domestic cat.
abstract: Canine parvovirus type 2a (CPV-2a) and type 2b (CPV-2b) have recently been isolated from cats throughout the world, and CPV-2b strain FP84 has been reported to be virulent in domestic cats. Although live feline panleucopenia virus (FPLV) vaccines protect domestic cats from CPV infection, the efficacy of inactivated FPLV vaccines has not been established. In this study, two domestic cats were vaccinated with a commercial inactivated FPLV vaccine and challenged with CPV-2b strain FP84 isolated from a domestic cat. The cats were protected against CPV-2b strain FP84 infection and their clinical signs were suppressed, although the two unvaccinated cats showed the typical clinical signs of parvovirus infection.
authors.affiliation: National Veterinary Assay Laboratory, Kokubunji, Tokyo 185-8511, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Gamoh
authors.forename: M
authors.initials: M
authors.lastname: Senda
authors.forename: Y
authors.initials: Y
authors.lastname: Inoue
authors.forename: O
authors.initials: O
authors.lastname: Itoh
mesh_terms: D000818:Animals; D002415:Cats; D005254:Feline Panleukopenia / Q000517:prevention & control*; D017993:Parvovirus, Canine / Q000276:immunology*; D016896:Treatment Outcome; D014611:Vaccination / Q000662:veterinary*; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
chemical_list: D015164:Vaccines, Inactivated; D014765:Viral Vaccines