title: Primary pleomorphic liposarcoma of bone: MRI findings and review of the literature.
abstract: Primary liposarcoma of bone is exceedingly rare. We report a case of primary pleomorphic liposarcoma in the humerus of a 38-year-old female. Radiographs demonstrated an expansile and osteolytic lesion extending from the head to the proximal part of the shaft in the right humerus. MR study showed a defined lesion in the humerus. The lesion had an iso-signal intensity and partial high-intensity lesion on T1-weighted images and a heterogeneous high signal intensity on T2-weighted images. Wide resection and proximal humeral endoprosthesis replacement were performed. Final pathological diagnosis of the lesion was pleomorphic liposarcoma. This is the second reported case of pleomorphic liposarcoma of the bone, and the first case presenting MRI findings for liposarcoma of bone.
authors.affiliation: Department of Orthopaedics, Juntendo University, School of Medicine, Hongo 2-1-1, Tokyo 113-8421, Japan. ttorigoe@med.juntendo.ac.jp
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Torigoe
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Terakado
authors.forename: Masaru
authors.initials: M
authors.lastname: Takase
authors.forename: Shigetaka
authors.initials: S
authors.lastname: Yamasaki
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kurosawa
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006811:Humerus / Q000473:pathology* / Q000601:surgery; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000628:therapy; D008279:Magnetic Resonance Imaging