Perinadine A, a novel tetracyclic alkaloid from marine-derived fungus Penicillium citrinum.
[structure: see text] A novel tetracyclic alkaloid, perinadine A (1), was isolated from the cultured broth of the fungus Penicillium citrinum, which was separated from the gastrointestine of a marine fish, and the structure was elucidated on the basis of spectroscopic data including 2D NMR spectra. Biogenetically, perinadine A (1) may be derived from citrinin (4), a well-known mycotoxin, and a scalusamide A-type pyrrolidine alkaloid.
Sasaki
Mai
M
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Tsuda
Masashi
M
Sekiguchi
Mitsuhiro
M
Mikami
Yuzuru
Y
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D009792:Oceans and Seas; D010407:Penicillium / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000470:Alkaloids; D011083:Polycyclic Compounds; C512189:perinadine A