Genetic comparison of H5N1 influenza A viruses isolated from chickens in Japan and Korea.
Outbreaks of highly pathogenic avian influenza (HPAI) caused by H5N1 virus occurred during 2003 to 2004 in Korea and Japan. The H5N1 viruses isolated in both countries were genetically similar at > 99% identity in the nucleotide sequences of all eight RNA segments, indicating that they belong to genotype V and are distinct from HPAI viruses prevalent in southeast Asia that belong to genotype Z. These findings indicate that the H5N1 viruses that caused the HPAI outbreaks in both Korea and Japan were derived from a common ancestor.
Mase
Masaji
M
Department of Infectious Diseases, National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba, Ibaraki, Japan. masema@affrc.go.jp
Kim
Jae-Hong
JH
Lee
Youn-Jeong
YJ
Tsukamoto
Kenji
K
Imada
Tadao
T
Imai
Kunitoshi
K
Yamaguchi
Shigeo
S
D000818:Animals; D002645:Chickens / Q000821:virology*; D005838:Genotype; D006389:Hemagglutinins, Viral / Q000032:analysis; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D005585:Influenza in Birds / Q000821:virology*; D007564:Japan; D007723:Korea; D009439:Neuraminidase / Q000032:analysis; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014764:Viral Proteins / Q000032:analysis
D006389:Hemagglutinins, Viral; D012367:RNA, Viral; D014764:Viral Proteins; D009439:Neuraminidase