title: The effect of otitis media in childhood on the development of middle ear admittance on reaching adulthood.
abstract: OBJECTIVE
  To determine the long-term change in static admittance values of subjects with a positive or negative history of otitis media (OM) and ventilation tube (VT) insertion; and to investigate the association between static admittance values and tympanic membrane abnormalities.
  
  
  METHODS
  Prospective follow-up study.
  
  
  METHODS
  A total of 358 subjects with or without a history of OM (OM+ or OM-) and VT insertion (VT+ or VT-) derived from a birth cohort that had been observed from preschool to adulthood.
  
  
  METHODS
  Otomicroscopic and tympanometric data obtained at subject ages 8 and 18 years.
  
  
  RESULTS
  Static admittance values generally increased with age. At age 8 years, static admittance values were highest in OM+VT+ ears and lowest in OM- ears. At age 18 years, the difference between OM+VT+ and OM+VT- ears was larger, while the difference in static admittance values between OM+VT- and OM- ears had disappeared. In the group of VT+ subjects, the proportion of extreme static admittance values increased from 16% to 35% between ages 8 and 18 years. Correlation coefficients of individual static admittance values at 8 and 18 years were high in all groups and ranged from 0.61 to 0.85. We could not demonstrate an intermediate role of tympanic membrane abnormalities in the relation between VTs and static admittance at young adult age, except for atrophy.
  
  
  CONCLUSIONS
  The static admittance value at age 8 years was a strong predictor for the value at age 18 years. A VT+ status was associated with a larger increase in static admittance than can be explained on the basis of age alone.
authors.affiliation: Department of Otorhinolaryngology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands. b.debeer@kno.umcn.nl
authors.forename: Brechtje
authors.initials: B
authors.lastname: de Beer
authors.forename: Ad
authors.initials: A
authors.lastname: Snik
authors.forename: Anne G M
authors.initials: AG
authors.lastname: Schilder
authors.forename: Kees
authors.initials: K
authors.lastname: Graamans
authors.forename: Gerhard A
authors.initials: GA
authors.lastname: Zielhuis
mesh_terms: D000158:Acoustic Impedance Tests / Q000379:methods*; D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004432:Ear, Middle / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008876:Middle Ear Ventilation; D010033:Otitis Media / Q000503:physiopathology*; D038781:Otoscopy; D011446:Prospective Studies