Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids.
Asymmetric reduction of oximes was performed by chromium(II) complexes of natural amino acids in aqueous phase or in H(2)O/DMF (1:1) solvent. Medium-to-quantitative chemoselectivity (54% to >95%) and low-to-medium enantioselectivity (5-50% ee) were found.
Micskei
Károly
K
Department of Inorganic and Analytical Chemistry, University of Debrecen, Hungary. kmicskei@delfin.unideb.hu
Holczknecht
Orsolya
O
Marchis
Valér
V
Lévai
Albert
A
Patonay
Tamás
T
Zucchi
Claudia
C
Pályi
Gyula
G
D000596:Amino Acids / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002857:Chromium / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D010091:Oximes / Q000737:chemistry; D013057:Spectrum Analysis; D013237:Stereoisomerism
D000596:Amino Acids; D010091:Oximes; D002857:Chromium; D002244:Carbon; D009584:Nitrogen