title: Intermittent explosive disorder-integrated research diagnostic criteria: convergent and discriminant validity.
abstract: Research on intermittent explosive disorder (IED) has been hindered by vague and restrictive DSM-IV diagnostic criteria. Integrated research criteria have been developed for IED (IED-IR) that address the DSM-IV criteria's shortcomings. The purpose of this study was to examine the convergent and discriminant validity of the IED-IR criteria set by comparing adults meeting these criteria (n=56) to healthy controls (n=56) and to individuals with an Axis I major mental disorder (n=33) or an Axis II personality disorder (n=22) diagnoses on measures of aggression (self-report and behavioral) and global functioning. IED-IR individuals demonstrated higher levels of aggression compared to the other three groups, and were rated as more impaired than the healthy control and Axis I individuals. Subgroup analyses showed that IED-IR subjects who did not meet DSM IED criteria did not differ from DSM IED subjects on self-report measures of aggressiveness or global functioning. Furthermore, the IED-IR subjects evidenced more behavioral aggression than their DSM-IED counterparts.
authors.affiliation: Department of Psychiatry, The Pritzker School of Medicine, The University of Chicago, Chicago, IL 60637, USA. mmcclosk@yoda.bsd.uchicago.edu
authors.forename: Michael S
authors.initials: MS
authors.lastname: McCloskey
authors.forename: Mitchell E
authors.initials: ME
authors.lastname: Berman
authors.forename: Kurtis L
authors.initials: KL
authors.lastname: Noblett
authors.forename: Emil F
authors.initials: EF
authors.lastname: Coccaro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000374:Aggression / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D016002:Discriminant Analysis; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires