title: Isolated endobronchial metastasis of Wilms' tumor.
abstract: Isolated endobronchial metastasis from extrapulmonary solid organ was rarely reported in previous literature. We report an isolated endobronchial metastasis of Wilms' tumor in a 4-year-old boy. He underwent right nephrectomy on account of Wilms' tumor at the age of 3 years. We performed a wedge resection of a metastasis to the right lower lobe of the lung a year later, followed by chemotherapy and irradiation of the involved lung over a period of 30 weeks. One and a half years later, he developed obstructive pneumonitis of the left lung. Fiberoptic bronchoscopy identified a tumor at the left main bronchus with near total bronchial obstruction, compatible with findings on a computed tomographic scan. Rigid bronchoscopy was performed to core out the obstructing tumor. It was reported as a metastatic Wilms' tumor. Successful reexpansion of the left upper lobe was achieved and he was discharged uneventfully, followed by adjuvant chemotherapy.
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, Republic of China.
authors.forename: Tzu-Peng
authors.initials: TP
authors.lastname: Lee
authors.forename: Ching
authors.initials: C
authors.lastname: Tzao
authors.forename: Jia-Hung
authors.initials: JH
authors.lastname: Liu
authors.forename: Cheng-Ping
authors.initials: CP
authors.lastname: Yu
authors.forename: Hsian-He
authors.initials: HH
authors.lastname: Hsu
authors.forename: Hsing-Nan
authors.initials: HN
authors.lastname: Chien
mesh_terms: D001999:Bronchoscopy; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008297:Male; D011014:Pneumonia / Q000209:etiology; D009396:Wilms Tumor / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery