Subtherapeutic risperidone serum concentrations in an adolescent during hemodialysis: a pharmacological puzzle.
A youngster with long-standing renal failure changed from peritoneal to hemodialysis, which worsened psychiatric symptoms and tics. TDM analysis of potential causes is presented.
Railton
Craig J
CJ
Department of Clinical Pharmacology and Toxicology, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada. craig.railton@utoronto.ca
Kapur
Bhushan
B
Koren
Gideon
G
D000293:Adolescent; D014150:Antipsychotic Agents / Q000097:blood*; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000097:blood; D000068882:Paliperidone Palmitate; D011743:Pyrimidines / Q000097:blood; D006435:Renal Dialysis; D018967:Risperidone / Q000097:blood*; D020323:Tics / Q000188:drug therapy*
D014150:Antipsychotic Agents; D007555:Isoxazoles; D011743:Pyrimidines; D018967:Risperidone; D000068882:Paliperidone Palmitate