Persistent psychoses in first episode patients.
This study was carried out to identify characteristics of patients with schizophrenia spectrum disorder who continue to have persistent psychoses (15%) for 2 years after initiation of treatment by comparing them to those who maintained full recovery of positive symptoms (42%) up to 2 years. Compared to those in recovery, significantly more patients with persistent psychoses were single, male, had a higher prevalence of drug abuse and abnormal EEG findings at presentation for treatment. Duration of untreated psychoses or untreated illness did not discriminate between the groups.
Manchanda
Rahul
R
Prevention and Early Intervention Program for Psychoses (PEPP), London Health Sciences Centre, 392 South Street, London, Ontario, Canada N6A 4G5. maryallen.amaral@lhsc.on.ca
Norman
Ross M G
RM
Malla
Ashok K
AK
Harricharan
Rajendra
R
Northcott
Sandra
S
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011618:Psychotic Disorders / Q000453:epidemiology* / Q000503:physiopathology / Q000517:prevention & control; D012074:Remission Induction; D012559:Schizophrenia / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control; D012720:Severity of Illness Index; D019966:Substance-Related Disorders / Q000453:epidemiology
D014150:Antipsychotic Agents