title: Cough and spontaneous rupture of a normal spleen.
abstract: Rupture of the spleen is a relatively common complication of trauma and many systemic disorders affecting the reticuloendothelial system, including infections and neoplasias. A rare subtype of rupture occurring spontaneously and arising from a normal spleen was recognized as a distinct clinicopathologic entity. The pathogenesis is debated in the absence of external trauma or predisposing disease. It has been reported in association with apparently trivial insults such as vomiting. We report a case of a patient with spontaneous rupture of a normal spleen. Interestingly, it was observed after severe coughing.
authors.affiliation: Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
authors.forename: Nagib T
authors.initials: NT
authors.lastname: Toubia
authors.forename: Maroun M
authors.initials: MM
authors.lastname: Tawk
authors.forename: Robyn M
authors.initials: RM
authors.lastname: Potts
authors.forename: Gary T
authors.initials: GT
authors.lastname: Kinasewitz
mesh_terms: D003371:Cough / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013156:Splenectomy; D013161:Splenic Rupture / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed