title: Atrovirisidone B, a new prenylated depsidone with cytotoxic property from the roots of Garcinia atroviridis.
abstract: A new prenylated depsidone, atrovirisidone B (2), together with naringenin (3) and 3,8"-binaringenin (4) were isolated from the roots of Garcinia atroviridis. Their structures were determined on the basis of spectral data interpretation. Compound 2 showed cytotoxic activity against human breast (MCF-7), human prostate (DU-145) and human lung (H-460) cancer cells.
authors.affiliation: Faculty of Medicine, Yarsi University, Jakarta 10510, Indonesia.
authors.forename: Dharma
authors.initials: D
authors.lastname: Permanaa
authors.forename: Faridah
authors.initials: F
authors.lastname: Abas
authors.lastname: Maulidiani
authors.forename: Khozirah
authors.initials: K
authors.lastname: Shaari
authors.forename: Johnson
authors.initials: J
authors.lastname: Stanslas
authors.forename: Abdul Manaf
authors.initials: AM
authors.lastname: Ali
authors.forename: Nordin Hj
authors.initials: NH
authors.lastname: Lajis
mesh_terms: D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects*; D005260:Female; D029760:Garcinia / Q000737:chemistry*; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D008297:Male; D008958:Models, Molecular; D018517:Plant Roots / Q000737:chemistry*; D011471:Prostatic Neoplasms
chemical_list: D007783:Lactones; C435807:atrovirisidone