Carbinol derivatives via rhodium-catalyzed addition of potassium trifluoro(organo)borates to aldehydes.
Reaction of potassium aryltrifluoroborates with aldehydes, in the presence of a rhodium catalyst, afforded carbinol derivatives in high yields under mild aqueous conditions; this efficient reaction proved to be general, allowing the production of highly hindered diarylmethanols and aliphatic aldehydes were also reactive under these conditions.
Pucheault
Mathieu
M
Laboratoire de Synthèse Sélective Organique (UMR 7573, CNRS), Ecole Nationale Supérieure de Chimie de Paris, Paris Cedex 05 75231, France.
Darses
Sylvain
S
Genet
Jean-Pierre
JP