title: The effect of laparoscopic and open donor nephrectomy on the long-term renal function in donor and recipient: a retrospective study.
abstract: Pneumoperitoneum, as used in laparoscopic donor nephrectomy (LDN), may result in negative effects on renal function in donor and recipient. This study compares long-term serum creatinine in donor and recipient after laparoscopic and open donor nephrectomy (ODN). A retrospective analysis of 120 LDN and 100 ODN donors and their recipients was performed. Serum creatinine of donor and recipient was recorded and analyzed. The follow-up period posttransplantation was 3 years. Serum creatinine in the recipients was significantly higher in the LDN groups the first week after transplantation. Serum creatinine in the donor was significantly higher in the LDN group at 1 day, 3 months, and 1 year posttransplant. Finally, creatinine levels remained 40% higher compared to preoperative values in both donor groups. LDN results in higher short-term serum creatinine levels in donor and recipient. Long-term serum creatinine levels were comparable after LDN or ODN in donor and recipient.
authors.affiliation: Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: May Y
authors.initials: MY
authors.lastname: Lind
authors.forename: Ingrid Mertens
authors.initials: IM
authors.lastname: Zur Borg
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Hazebroek
authors.forename: Wim C J
authors.initials: WC
authors.lastname: Hop
authors.forename: Ian P J
authors.initials: IP
authors.lastname: Alwayn
authors.forename: Willem
authors.initials: W
authors.lastname: Weimar
authors.forename: Jan N M
authors.initials: JN
authors.lastname: Ijzermans
mesh_terms: D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D010535:Laparoscopy; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D003404:Creatinine