Heteronuclear decoupling interference during symmetry-based homonuclear recoupling in solid-state NMR.
We examine the influence of continuous-wave heteronuclear decoupling on symmetry-based double-quantum homonuclear dipolar recoupling, using experimental measurements, numerical simulations, and average Hamiltonian theory. There are two distinct regimes in which the heteronuclear interference effects are minimized. The first regime utilizes a moderate homonuclear recoupling field and a strong heteronuclear decoupling field; the second regime utilizes a strong homonuclear recoupling field and a weak or absent heteronuclear decoupling field. The second regime is experimentally accessible at moderate or high magic-angle-spinning frequencies and is particularly relevant for many realistic applications of solid-state NMR recoupling experiments to organic or biological materials.
Marin-Montesinos
Ildefonso
I
School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK.
Brouwer
Darren H
DH
Antonioli
Giancarlo
G
Lai
Wai Cheu
WC
Brinkmann
Andreas
A
Levitt
Malcolm H
MH
D000409:Alanine / Q000737:chemistry*; D002247:Carbon Isotopes; D005650:Fumarates / Q000737:chemistry*; D005998:Glycine / Q000737:chemistry*; D015394:Molecular Structure; D009587:Nitrogen Isotopes; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*
D002247:Carbon Isotopes; D005650:Fumarates; D009587:Nitrogen Isotopes; C032005:fumaric acid; D000409:Alanine; D005998:Glycine