title: Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC.
abstract: The present work describes the isolation of camptothecin and 9-methoxycamptothecin from the aerial parts of Nothapodytes foetida by semipreparative high-performance liquid chromatography because the separation of compounds by conventional procedures is tedious and cumbersome. The purity of the isolates is determined by physicochemical data and liquid chromatography-mass spectrometry.
authors.affiliation: Regional Research Laboratory (CSIR), Jammu-180 001, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Puri
authors.forename: G
authors.initials: G
authors.lastname: Handa
authors.forename: B A
authors.initials: BA
authors.lastname: Bhat
authors.forename: V K
authors.initials: VK
authors.lastname: Gupta
authors.forename: T
authors.initials: T
authors.lastname: Amna
authors.forename: N
authors.initials: N
authors.lastname: Verma
authors.forename: R
authors.initials: R
authors.lastname: Anand
authors.forename: K L
authors.initials: KL
authors.lastname: Dhar
authors.forename: G N
authors.initials: GN
authors.lastname: Qazi
mesh_terms: D002166:Camptothecin / Q000031:analogs & derivatives* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D002853:Chromatography, Liquid / Q000379:methods; D019684:Magnoliopsida / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods
chemical_list: C025724:9-methoxycamptothecin; D002166:Camptothecin