Recent advances in the use of phosphorus-centered radicals in organic chemistry.
This tutorial review aims at presenting recent contributions dealing with organic chemistry of organophosphorus radicals. The first part briefly lays out the physical organic background of such intermediates. In a second part the use of organophosphorus radicals possessing a P-H bond that can undergo homolytic cleavage as alternative mediators is detailed. The third part is focused on radical additions of phosphorus-centered radicals to unsaturated compounds, an old reaction that is being rejuvenated. Lastly, radical eliminations of phosphorus-centered radical are introduced in the fourth part. Most of the latter are relatively novel reactions, and have never been reviewed previously.
Leca
Dominique
D
Université Pierre et Marie Curie, Institut de chimie moléculaire (FR 2769), Laboratoire de chimie organique (UMR CNRS 7611), C. 229, 4 place Jussieu, 75005, Paris, France.
Fensterbank
Louis
L
Lacôte
Emmanuel
E
Malacria
Max
M
D002625:Chemistry, Organic / Q000379:methods* / Q000639:trends*; D002627:Chemistry, Physical / Q000379:methods* / Q000639:trends*; D005609:Free Radicals / Q000737:chemistry*; D009930:Organic Chemicals / Q000032:analysis / Q000737:chemistry*; D017553:Phosphorus Compounds / Q000032:analysis / Q000737:chemistry*
D005609:Free Radicals; D009930:Organic Chemicals; D017553:Phosphorus Compounds