Apatite formation on poly(2-hydroxyethyl methacrylate)-silica hybrids prepared by sol-gel process.
Hybrids of poly(2-hydroxyethyl methacrylate) (PHEMA), a polymer that has been employed in a wide variety of biomedical applications, and silica-gel, which exhibits a well-known bioactivity, were produced. The obtained hybrids were characterized and their in vitro ability to induce the formation of a calcium phosphate layer on the surface was evaluated. The surface area of hybrids decreased with increasing amounts of PHEMA so that hybrids with more than approximately 40% PHEMA are virtually non-porous. All hybrids induced the formation of a calcium phosphate layer on their surfaces when soaked into simulated body fluid. The induction time and the morphology of the apatite layer varied according to the polymer content.
Costa
Ricardo O R
RO
Centro de Desenvolvimento da Tecnologia Nuclear, CDTN/CNEN, Rua Prof. Mário Werneck, Campus da UFMG, Belo Horizonte, MG, Brazil, 30123-970.
Pereira
Marivalda M
MM
Lameiras
Fernando S
FS
Vasconcelos
Wander L
WL
D001031:Apatites / Q000737:chemistry*; D001826:Body Fluids / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000032:analysis / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D008422:Materials Testing; D010316:Particle Size; D044367:Phase Transition; D011102:Polyhydroxyethyl Methacrylate / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
D001031:Apatites; D020099:Coated Materials, Biocompatible; D011102:Polyhydroxyethyl Methacrylate; D012822:Silicon Dioxide