[Risk factors and preventive steps for nasosinusitis after radiotherapy of nasopharyngeal carcinoma].
OBJECTIVE
To study the risk factors and preventive steps of nasosinusitis after radiotherapy of nasopharyngeal carcinoma (NPC).


METHODS
Two hundreds and thirtyone NPC patients were retrospectively analysed.


RESULTS
Among 231 NPC patients, 98 patients (42.4%) had nasosinusitis before radiotherapy, 165 patients (66.7%) suffered from nasosinusitis after radiotherapy. The rate of nasosinusitis in NPC patients with high T stage and nasalcavity anatomical aberrance was higher than in others (P = 0.014, CR = 1. 973; P = 0. 034, OR = 2.156), and the rate of nasosinusitis in NPC patients with nasopharynx therapy was low (P = 0.008, OR = 0.675), most patients with nasosinusitis before radiotherapy had not any improve after radiotherapy,and effected the effect of radiotherapy.


CONCLUSIONS
To reduce nasosinusitis after radiotherapy and improve patients quality of life, we suggest that nasopharyngeal cavity therapy should be carried out during and after irradiation for NPC patients, especially for those patients with high T stage and nasalcavity anatomical aberrance, and for those who had nasosinusitis before radiotherapy.
Li
Hui
H
Department of Otolaryngology, First Clinical Affiliated Hospital, Jinan University, Guangzhou, 510630, China. dl-lh1995@163.com
Wang
Jiqun
J
Wang
Lihua
L
Li
Hengguo
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000150:complications / Q000532:radiotherapy*; D012189:Retrospective Studies; D012852:Sinusitis / Q000209:etiology / Q000517:prevention & control*