title: MR-guided percutaneous ethanol injection for hepatocellular carcinoma in a 0.2T open MR system.
abstract: The purpose of this work is to describe our experience with single-session percutaneous ethanol injection (PEI) under the guidance of 0.2-T open MRI for hepatocellular carcinomas (HCC) that were not suitable for ablation under ultrasound (US) or computed tomography (CT) guidance. None of the lesions (N = 7) were detectable on US. MRI was chosen over CT as the guidance modality because the nodules were located in the hepatic dome (N = 4) or were invisible on noncontrast CT (N = 3). All of the nodules were targeted successfully, and apparently complete tumor necrosis was achieved in six nodules (86%). During a follow-up of one to 41 months, only one patient developed local recurrence four months after PEI. MR-guided PEI is feasible and effective for treating HCC when other imaging guidance methods are not appropriate.
authors.affiliation: Department of Radiological Sciences, University of California-Los Angeles School of Medicine, Los Angeles, California 90095-1721, USA.
authors.forename: Young Jun
authors.initials: YJ
authors.lastname: Kim
authors.forename: Steven S
authors.initials: SS
authors.lastname: Raman
authors.forename: Nam C
authors.initials: NC
authors.lastname: Yu
authors.forename: David S K
authors.initials: DS
authors.lastname: Lu
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000431:Ethanol / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
chemical_list: D000431:Ethanol