title: Intratesticular injection of a balanced zinc solution for permanent sterilization of dogs.
abstract: Five male mature dogs with normal sex organs and normal pre-study semen evaluation received intratesticular injections of a sterile solution of balanced zinc gluconate. Semen without sperm could be collected on days 26, 30, 35 and 51 from 4 dogs. The dogs achieved penile erection but no ejaculation before these days. There were no significant adverse effects and no change in the dog behavior during the time that they were observed. Histopathological findings documented virtually complete fibrosis of seminiferous tubules and Leydig cells on days 60 and 75. This preliminary study concludes that balanced zinc gluconate may be used to sterilize dogs.
authors.affiliation: Queen Saovabha Memorial Institute, Thai Red Cross Society, WHO Collaborating Centre for Research on Rabies Pathogenesis and Prevention. tepsumethanonv@yahoo.com
authors.forename: Veera
authors.initials: V
authors.lastname: Tepsumethanon
authors.forename: Henry
authors.initials: H
authors.lastname: Wilde
authors.forename: Thiravat
authors.initials: T
authors.lastname: Hemachudha
mesh_terms: D000818:Animals; D004285:Dogs; D005942:Gluconates / Q000008:administration & dosage*; D007267:Injections; D008297:Male; D013245:Sterilization, Reproductive / Q000379:methods / Q000662:veterinary*; D013737:Testis
chemical_list: D005942:Gluconates; C030691:gluconic acid