Intermolecular C-N addition of amides and S-N addition of sulfinamides to arynes.
An efficient, mild, transition-metal-free method has been developed for the intermolecular C-N sigma-bond addition of amides and S-N sigma-bond addition of sulfinamides to arynes to form one C-C bond and one heteroatom-carbon bond in one step at room temperature. Evidence for a stepwise mechanism is provided.
Liu
Zhijian
Z
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Larock
Richard C
RC
D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000577:Amides; D006841:Hydrocarbons, Aromatic