Inflammatory markers: linking unstable plaques to coronary event, an interventional perspective.
Abundant data links inflammatory mechanisms to atheromatous plaque destabilization leading to plaque rupture and coronary events. The discovery of inflammatory cells and inflammatory mediators within atherosclerotic plaques prone to rupture led to a series of studies demonstrating an association between various markers of inflammation and future coronary events. Inflammatory markers have also been used in patients undergoing coronary angioplasty in an attempt to predict restenosis and risk for post-procedural coronary events. This review article provides an overview on the potential use of inflammatory markers in the context of coronary interventions.
Aronson
Doron
D
Department of Cardiology, Rambam Medical Center, Haifa, Israel. d_aronson@rambam.health.gov.il
D015906:Angioplasty, Balloon, Coronary; D015415:Biomarkers / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood* / Q000150:complications / Q000628:therapy; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D009203:Myocardial Infarction / Q000097:blood / Q000209:etiology*; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D012307:Risk Factors
D015415:Biomarkers; D018836:Inflammation Mediators