title: A comparison of MR cholangiopancreatography at 1.5 and 3.0 Tesla.
abstract: Clinical MR systems operating at 3.0 Tesla have the potential to significantly improve spatial resolution due to the boost in intrinsic signal to noise ratio. However, body imaging at these field strengths presents a number of technical challenges. We performed a prospective pilot study in which 10 patients underwent an MR cholangiopancreatography (MRCP) examination consecutively on 1.5 and 3.0 Tesla systems (both Philips Intera). An axial half Fourier segmented turbo spin echo (HASTE) sequence and a coronal thick-slab 2D turbo-spin echo (TSE) sequence were compared on both systems. A reader measured the signal intensity (SI) ratios of common bile duct (CBD): liver, and CBD: fat on HASTE images and CBD: liver on the TSE images. A second reader performed a qualitative analysis of the intrahepatic and extrahepatic biliary anatomy. Quantitative data was compared using the paired t-test and qualitative data with the paired Wilcoxon signed rank test with p < 0.05. The quantitative analysis of the HASTE sequences showed a slightly higher signal intensity ratio (CBD:liver) at 3.0 Tesla compared with 1.5 Tesla (8.1 vs 5.6, p = 0.002). No significant difference was found between the SI ratios of (CBD:fat) on HASTE images or (CBD:liver) on TSE images. The qualitative analysis showed superior image quality of 3.0 Tesla over 1.5 Tesla images on both HASTE (31 vs 25, p = 0.032), and TSE sequences (34 vs 28, p = 0.043). This pilot study shows that MRCP is feasible at 3.0 Tesla with some improvement in image quality and signal characteristics. Further development may be achieved with sequence optimization and improved coil design.
authors.affiliation: Imaging Sciences Department (Clinical Sciences Centre), Hammersmith Hospital, Faculty of Medicine, Imperial College, London, UK.
authors.forename: D P
authors.initials: DP
authors.lastname: O'Regan
authors.forename: J
authors.initials: J
authors.lastname: Fitzgerald
authors.forename: J
authors.initials: J
authors.lastname: Allsop
authors.forename: D
authors.initials: D
authors.lastname: Gibson
authors.forename: D J
authors.initials: DJ
authors.lastname: Larkman
authors.forename: D
authors.initials: D
authors.lastname: Cokkinos
authors.forename: J V
authors.initials: JV
authors.lastname: Hajnal
authors.forename: S A
authors.initials: SA
authors.lastname: Schmitz
mesh_terms: D000328:Adult; D000368:Aged; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods / Q000592:standards*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010865:Pilot Projects; D011446:Prospective Studies