title: Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: new insights about an old question.
abstract: This article presents the proceedings of the symposium "Endogenous Opioids and Voluntary Ethanol Consumption: What Have We Learnt From Knock-out Mice?" presented at the meeting of the International Society for Biomedical Research on Alcoholism held in Heidelberg/Mannheim, Germany, in September/October 2004. The organizers and chairpersons were Michael S. Cowen and Carles Sanchis-Segura. The presentations were as follows: (1) Regulation of the Opioid System by Alcohol: Comparison of Alcohol-Preferring and -Nonpreferring Strains by Michael S. Cowen; (2) Endogenous Opioids and Alcohol: Lessons From Microdialysis and Knock-out Mice by M. Foster Olive; (3) From Neurochemistry to Neuroanatomy: The Hypothalamic Arcuate Nucleus as a Main Site for Ethanol-Opioids Interaction by Carles Sanchis-Segura; (4) Sensitivity to Ethanol Is Modulated by beta-Endorphin in Transgenic Mice by Judy E. Grisel, Amanda J. Roberts, and George F. Koob; and () The mu-Opioid Receptor Modulates Acute Ethanol Sensitivity and Ethanol Withdrawal Severity by Sandra Ghozland.
authors.affiliation: Howard Florey Institute, University of Melbourne, Australia. sergura@zi-mannheim.de
authors.forename: Carles
authors.initials: C
authors.lastname: Sanchis-Segura
authors.forename: Judy E
authors.initials: JE
authors.lastname: Grisel
authors.forename: M Foster
authors.initials: MF
authors.lastname: Olive
authors.forename: Sandra
authors.initials: S
authors.lastname: Ghozland
authors.forename: George F
authors.initials: GF
authors.lastname: Koob
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Roberts
authors.forename: Michael S
authors.initials: MS
authors.lastname: Cowen
mesh_terms: D000430:Alcohol Withdrawal Delirium / Q000503:physiopathology; D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology*; D000431:Ethanol / Q000494:pharmacology; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009042:Motivation; D011957:Receptors, Opioid / Q000502:physiology*; D017450:Receptors, Opioid, mu / Q000502:physiology; D001615:beta-Endorphin / Q000502:physiology
chemical_list: D011957:Receptors, Opioid; D017450:Receptors, Opioid, mu; D000431:Ethanol; D001615:beta-Endorphin