title: Fertility-sparing options for patients with gynecologic malignancies.
abstract: Gynecologic malignancies are most often diagnosed in postmenopausal women, but these malignancies also arise in premenopausal women, in whom issues of fertility can be a major concern. An increasing number of women are delaying childbearing. This has led to a significant increase in the number of women diagnosed with a gynecologic malignancy before desired completion of childbearing. Many of the standard treatments for these malignancies result in permanent sterility; however, there are now options for select young women who desire to preserve fertility. Patients should be told that data on fertility-sparing procedures are limited and that many of these options are of an experimental, nonstandard nature. The care of these patients is challenging and complex and requires a multidisciplinary approach, which should include gynecologic oncologists, reproductive endocrinologists, and perinatologists.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Women's Health, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, USA.
authors.forename: Mario M
authors.initials: MM
authors.lastname: Leitao
authors.forename: Dennis S
authors.initials: DS
authors.lastname: Chi
mesh_terms: D016889:Endometrial Neoplasms / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005298:Fertility; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000601:surgery