Staphylococcus aureus as a risk factor for bloodstream infection in children with postoperative mediastinitis.
Bloodstream infection (BSI) complicates postoperative mediastinitis in >50% of cases. In this retrospective cohort study from 1995-2003, postoperative mediastinitis caused by Staphylococcus aureus was an independent risk factor for the development of BSI (adjusted odds ratio, 6.4; 95% confidence interval, 1.4-29.3). Postoperative mediastinitis caused by S. aureus has a higher intrinsic risk of being complicated by BSI than mediastinitis caused by other pathogens.
Shah
Samir S
SS
Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Lautenbach
Ebbing
E
Long
Caroline B
CB
Tabbutt
Sarah
S
Gaynor
J William
JW
Bilker
Warren B
WB
Bell
Louis M
LM
D000293:Adolescent; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D016017:Odds Ratio; D011336:Probability; D012016:Reference Values; D012189:Retrospective Studies; D018570:Risk Assessment; D017678:Sex Distribution; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D015996:Survival Rate; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents