title: Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development.
abstract: The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes several pathogens of veterinary and human medical importance. An understanding of the diversity of Anaplasma major surface proteins (MSPs), including those MSPs that modulate infection, development of persistent infections, and transmission of pathogens by ticks, is derived in part, by characterization and phylogenetic analyses of geographic strains. Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis.
authors.affiliation: Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078-2007, USA. jose_delafuente@yahoo.com
authors.forename: José
authors.initials: J
authors.lastname: de la Fuente
authors.forename: Ala
authors.initials: A
authors.lastname: Lew
authors.forename: Hans
authors.initials: H
authors.lastname: Lutz
authors.forename: Marina L
authors.initials: ML
authors.lastname: Meli
authors.forename: Regina
authors.initials: R
authors.lastname: Hofmann-Lehmann
authors.forename: Varda
authors.initials: V
authors.lastname: Shkap
authors.forename: Thea
authors.initials: T
authors.lastname: Molad
authors.forename: Atilio J
authors.initials: AJ
authors.lastname: Mangold
authors.forename: Consuelo
authors.initials: C
authors.lastname: Almazán
authors.forename: Victoria
authors.initials: V
authors.lastname: Naranjo
authors.forename: Christian
authors.initials: C
authors.lastname: Gortázar
authors.forename: Alessandra
authors.initials: A
authors.lastname: Torina
authors.forename: Santo
authors.initials: S
authors.lastname: Caracappa
authors.forename: Ana L
authors.initials: AL
authors.lastname: García-Pérez
authors.forename: Marta
authors.initials: M
authors.lastname: Barral
authors.forename: Beatriz
authors.initials: B
authors.lastname: Oporto
authors.forename: Luigi
authors.initials: L
authors.lastname: Ceci
authors.forename: Grazia
authors.initials: G
authors.lastname: Carelli
authors.forename: Edmour F
authors.initials: EF
authors.lastname: Blouin
authors.forename: Katherine M
authors.initials: KM
authors.lastname: Kocan
mesh_terms: D042322:Anaplasma marginale / Q000145:classification / Q000235:genetics* / Q000276:immunology; D000712:Anaplasmosis / Q000175:diagnosis* / Q000517:prevention & control*; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis*; D001428:Bacterial Vaccines; D002417:Cattle; D010802:Phylogeny; D012698:Serologic Tests / Q000662:veterinary; D020080:Tandem Repeat Sequences; D014611:Vaccination / Q000662:veterinary*
chemical_list: D001425:Bacterial Outer Membrane Proteins; D001428:Bacterial Vaccines