[Synthesis, characterization and blood compatibility studies of waterproof breathable polyurethanes].
Adopting the two-step method and changing the proportion between PEG (Polyethylene glycol) and PTMG (poly (tetrahydrofuran), we used the MDI (4,4'-diphenylmethane diisocyanate) and short chain extender BDO (1,4-butanediol) as hard segment, the PTMG and PEG as soft segment, and hence prepared a series of polyether-based thermoplastic polyurethanes. FTIR showed the structure character of these polyurethanes. The determination of mechanics property and water contact angles revealed their good mechanics properties and hydrophilicity. Blood compatibility was evaluated by hemolysis test and platelet adhesion test, which revealed their good hemocompatibility. So those polyurethanes may be of wide application in the future.
Wang
Peng
P
Department of Polymer Material Science Engineering, Sichuan University, Chengdu, China.
Luo
Jianbin
J
Du
Minhui
M
He
Chengsheng
C
Fan
Cuirong
C
Zhong
Yinping
Y
D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D002072:Butylene Glycols / Q000737:chemistry*; D017953:Isocyanates / Q000737:chemistry; D008422:Materials Testing; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011140:Polyurethanes / Q000138:chemical synthesis* / Q000737:chemistry; D011817:Rabbits; D001559:Benzhydryl Compounds
D001672:Biocompatible Materials; D002072:Butylene Glycols; D017953:Isocyanates; D011092:Polyethylene Glycols; D011108:Polymers; D011140:Polyurethanes; C524501:poly(tetrahydrofuran); C039681:1,4-butanediol; C005969:4,4'-diphenylmethane diisocyanate; D001559:Benzhydryl Compounds