title: Gastroinvasive Helicobacter infection in an Ocelot (Leopardus pardalis).
abstract: Highly invasive Helicobacter-like organisms were found in a 19-year-old female ocelot (Leopardus pardalis) with multiple ulcers in the fundic region of the stomach. The bacteria, resembling Helicobacter heilmannii, were located largely within canaliculi or in the cytosol of parietal cells. Except in the ulcerative lesions, parietal cells were hyperplastic, while chief cells and neck mucous cells were reduced in number. The term "gastroinvasive Helicobacter-like organism" was applied. It seems probable that this organism differs from other Helicobacter organisms in pathogenicity, and possible that its behaviour in vitro would help it to evade antibacterial treatment.
authors.affiliation: Ishikari Livestock Hygiene Service Centre, 3 Hitsujigaoka, Toyohira, Sapporo 062-0045, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kanou
authors.forename: D
authors.initials: D
authors.lastname: Fukui
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Shibahara
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: K
authors.initials: K
authors.lastname: Kadota
mesh_terms: D000818:Animals; D045989:Felidae; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D041981:Gastrointestinal Tract / Q000382:microbiology / Q000473:pathology; D016998:Helicobacter / Q000145:classification / Q000302:isolation & purification / Q000472:pathogenicity*; D016481:Helicobacter Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D018247:Helicobacter heilmannii / Q000302:isolation & purification; D013276:Stomach Ulcer / Q000382:microbiology / Q000473:pathology / Q000662:veterinary