Successful liver transplantation for giant cell hepatitis and Coombs-positive hemolytic anemia: a case report.
Giant cell hepatitis (GCH) with autoimmune hemolytic anemia (AHA) is a distinct entity with an aggressive course. Drugs, autoimmunity, and viruses have been implicated in its etiology. Without treatment, liver dysfunction is progressive and fatal. Although successful immunosuppressive treatment has been reported, a few patients have undergone liver transplantation with recurrence of the primary disease in the allograft. We report, an 18-year-old boy with progressive GCH with AHA without recurrence in the allograft following deceased donor (DD) liver transplantation.
Akyildiz
Murat
M
Department of Gastroenterology and Hepatology, Ege University Organ Transplant and Research Center, Izmir, Turkey.
Karasu
Zeki
Z
Arikan
Cigdem
C
Nart
Deniz
D
Kilic
Murat
M
D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D003298:Coombs Test; D015726:Giant Cells / Q000473:pathology; D006505:Hepatitis / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation; D008297:Male