Cobalt-catalyzed hydrohydrazination of dienes and enynes: access to allylic and propargylic hydrazides.
[reaction: see text] The cobalt-catalyzed hydrohydrazination reaction of dienes and enynes is presented. Allylic and propargylic hydrazines were obtained in synthetically useful yields (allylic amines, 60-90%; propargylic amines, 47-83%) and good chemo- and regioselectivity.
Waser
Jérôme
J
Laboratorium für Organische Chemie, ETH Hönggerberg, HCI H335 8093 Zürich, Switzerland.
González-Gómez
José C
JC
Nambu
Hisanori
H
Huber
Pascal
P
Carreira
Erick M
EM
D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D006900:Hydroxylation; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000475:Alkenes; D006834:Hydrazines; D014867:Water; D003035:Cobalt