[Research on effect of total saponins of yinfenglun on uterine].
OBJECTIVE
To research the effect of total saponins of Yinfenglun on uterine.


METHODS
Models of uterine inflammation were established to observe the effect of total saponins of Yinfenglun. Uterine contractive effects were studied on rats in vitro and on rabbit in vivo. Weight of uterus and levels of estrogen and progestogen were determined.


RESULTS
Total Saponins of Yinfenglun had the ameliorated tendency to metritis of model rats, and increased the contractive range and motorricity of uterine of rats in vitro and of rabbit in vivo. The effect to uterus in vivo maintained longer. Total saponins of Yinfenglun could increase the weight of uterus and have an increased tendency on the content of estrogen, but not the level of progestogen.


CONCLUSIONS
There are obvious effects on uterine of total saponins of Yinfenglun, which are related to its clinical use.
Peng
Dai-yin
DY
Anhui College of Traditional Chinese Medicine, Hefei 230038, China.
Liu
Qing-yun
QY
Dai
Min
M
Zi
Xiao-mei
XM
Xu
Xian-xiang
XX
D000818:Animals; D004958:Estradiol / Q000097:blood*; D005260:Female; D007249:Inflammation / Q000473:pathology; D019686:Lamiaceae / Q000737:chemistry; D051379:Mice; D009929:Organ Size / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry; D011372:Progestins / Q000097:blood; D011817:Rabbits; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*; D014591:Uterine Diseases / Q000473:pathology; D014599:Uterus / Q000033:anatomy & histology*
D011372:Progestins; D012503:Saponins; D004958:Estradiol