Atrovirisidone B, a new prenylated depsidone with cytotoxic property from the roots of Garcinia atroviridis.
A new prenylated depsidone, atrovirisidone B (2), together with naringenin (3) and 3,8"-binaringenin (4) were isolated from the roots of Garcinia atroviridis. Their structures were determined on the basis of spectral data interpretation. Compound 2 showed cytotoxic activity against human breast (MCF-7), human prostate (DU-145) and human lung (H-460) cancer cells.
Permanaa
Dharma
D
Faculty of Medicine, Yarsi University, Jakarta 10510, Indonesia.
Abas
Faridah
F
Maulidiani
Shaari
Khozirah
K
Stanslas
Johnson
J
Ali
Abdul Manaf
AM
Lajis
Nordin Hj
NH
D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects*; D005260:Female; D029760:Garcinia / Q000737:chemistry*; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D008297:Male; D008958:Models, Molecular; D018517:Plant Roots / Q000737:chemistry*; D011471:Prostatic Neoplasms
D007783:Lactones; C435807:atrovirisidone