title: [Leptin concentration in pregnant women with hypertension and its correlation with body mass index].
abstract: Arterial hypertension is one of the reasons of high rate of mother and fetal mortality. The main aim of the study was to find the correlation between the leptin concentration, the BMI value and the risk of hypertension in pregnancy.
  
  
  METHODS
  the study was conducted in High Risk Pregnancy Department of the Medical University of Lodz in 2001-2003. The study group consists of 126 pregnant women with arterial hypertension. BMI, leptin concentration and arterial blood pressure were measured. The measurement was done every 4 weeks from 20 weeks of gestation, Leptin Elisa kit was used. The leptin measurement was done spectrophotometrically.
  
  
  RESULTS
  In group of obese pregnant women we found the correlation between BMI and high blood pressure if the high BMI was observed before pregnancy. Leptin concentration and the risk of hypertension was higher in the group of obese pregnant women.
  
  
  CONCLUSIONS
  In obese pregnant women the risk of HA was high and the high value of BMI before pregnancy is the risk factor of hypertension in pregnancy.
authors.affiliation: Klinika Patologii Ciazy I Katedry Połoznictwa i Ginekologii Uniwersytetu Medycznego, Lodzi.
authors.forename: Dorota
authors.initials: D
authors.lastname: Estemberg
authors.forename: Urszula
authors.initials: U
authors.lastname: Kowalska-Koprek
authors.forename: Ewa
authors.initials: E
authors.lastname: Kuś
authors.forename: Paweł
authors.initials: P
authors.lastname: Estemberg
authors.forename: Agata
authors.initials: A
authors.lastname: Karowicz-Bilińska
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology*; D020738:Leptin / Q000097:blood*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000503:physiopathology*
chemical_list: D020738:Leptin