[Assessment of fetal fibronectin concentration in identifying patients at risk for preterm delivery].
METHODS
Identifying patients at risk for preterm delivery continues to be difficult.


OBJECTIVE
This study aimed at evaluating fetal fibronectin concentrations in cervical secretions measured by an enzyme-linked immunosorbent assay, as a tool for of premature delivery screening in patients with preterm uterine contractions.


METHODS
Symptomatic 115 women, admitted to Department of Perinatology (RIPMMH) between 24 weeks 0 days and 34 weeks 6 days, with intact amniotic membranes, single pregnancy, cervical dilatation <3 cm and with no cerclage were included. Samples of the cervical secretion were taken every week until the delivery or to hospital discharge.


RESULTS
The enzyme-linked immunosorbent assays revealed sensitivity of 73.7% and specificity of 90.9%.


CONCLUSIONS
This test was found to be a good tool for the prediction of premature delivery.
Pieta-Dolińska
Agnieszka
A
Klinika Perinatologii, Instytutu Centrum Zdrowia Matki Polki, Lódź.
Jaczewski
Bogumił
B
Woźniak
Piotr
P
Oszukowski
Przemysław
P
D002584:Cervix Uteri / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005326:Fetal Proteins / Q000032:analysis / Q000378:metabolism*; D005353:Fibronectins / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000175:diagnosis* / Q000517:prevention & control; D011044:Poland; D011237:Predictive Value of Tests; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012307:Risk Factors; D014590:Uterine Contraction; D014621:Vagina / Q000737:chemistry*
D005326:Fetal Proteins; D005353:Fibronectins