title: [Long- term results after radical resection in patients with rectal cancer].
abstract: OBJECTIVE
  To analyze the long- term results of radical resection for rectal cancer and the factors influencing the operative results.
  
  
  METHODS
  From January 1990 to December 1999, clinical data of 689 patients who underwent radical resection for rectal cancer were analyzed retrospectively.
  
  
  RESULTS
  The overall operative mortality was 0.7%, the follow- up rate was 96.7%, the median survival rate was 67.4 months. The 1-, 3-, 5- and 10-year survival rate after operation was 89.9%, 77.3%, 69.6% and 63.3% respectively. Univariate analysis showed that the survival rate was related with the first onset symptom, tumor location, infiltrated circumference of intestine, T staging, Dukes staging, histological type, extent of lymph node metastasis and operative approaches. Multivariate analysis showed that tumor location, histological type, invasive depth and Dukes staging were independent prognostic factors.
  
  
  CONCLUSIONS
  The long-term efficacy after radical resection for rectal cancer is correlated with tumor location, histological type, invasive depth and Dukes staging.
authors.affiliation: Department of Abdominal Surgery, Tumor Hospital, Sun Yat-sen University, Guangzhou 510060, China. wds@medmail.com.cn
authors.forename: De-sen
authors.initials: DS
authors.lastname: Wan
authors.forename: Pei-rong
authors.initials: PR
authors.lastname: Ding
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Wu
authors.forename: Li-ren
authors.initials: LR
authors.lastname: Li
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Pan
authors.forename: Zhi-wei
authors.initials: ZW
authors.lastname: Zhou
authors.forename: Zhen-hai
authors.initials: ZH
authors.lastname: Lu
authors.forename: Gong
authors.initials: G
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012007:Rectum / Q000473:pathology; D012044:Regression Analysis; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome