title: Evolution of microarray analysis.
abstract: Reddy's very thorough review of the history of gene expression analysis of neurodegenerative disease made me think about the early days of microarrays, so I want to reminisce a little before commenting on the evolution of the technology and some issues that I think still continue to plague us.
authors.affiliation: The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA. jloring@burnham.org
authors.forename: Jeanne F
authors.initials: JF
authors.lastname: Loring
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D005544:Forecasting; D020869:Gene Expression Profiling / Q000379:methods* / Q000639:trends*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods* / Q000639:trends*; D014018:Tissue Distribution
chemical_list: D015415:Biomarkers; D009419:Nerve Tissue Proteins