title: [Routine otorhinolaryngological examination in patients with cystic fibrosis].
abstract: OBJECTIVE
  Data on the prevalence of otorhinolaryngological (ORL) symptoms in patients with cystic fibrosis (CF) are limited. A standard annual examination would be useful for definition of risk factors and/or management alternatives for these symptoms.
  
  
  METHODS
  Prospective observational study of an unselected group of CF patients.
  
  
  METHODS
  Between 1997 and 2004, 123 CF patients were routinely examined. The examinations included nasal endoscopy and audiological evaluation.
  
  
  RESULTS
  All patients who were approached to take part in the study gave their consent and were extremely cooperative. In 40% of the patients nasal polyps were found endoscopically. In 22% rhinological surgery had already been performed. Of the 123 patients, 13 (12%) showed different grades of sensorineural hearing loss, and all of these patients had received aminoglycoside antibiotics.
  
  
  CONCLUSIONS
  CF patients demonstrate a high prevalence of ORL symptoms. Therefore, an annual standard examination would provide data for identifying potential risk factors and for optimizing the management of these symptoms in CF patients.
authors.affiliation: Univ.-HNO-Klinik Tübingen. assen.koitschev@med.uni-tuebingen.de
authors.forename: A
authors.initials: A
authors.lastname: Koitschev
authors.forename: A
authors.initials: A
authors.lastname: Wolff
authors.forename: C
authors.initials: C
authors.lastname: Koitschev
authors.forename: S
authors.initials: S
authors.lastname: Preyer
authors.forename: R
authors.initials: R
authors.lastname: Ziebach
authors.forename: M
authors.initials: M
authors.lastname: Stern
mesh_terms: D000293:Adolescent; D000328:Adult; D000617:Aminoglycosides / Q000009:adverse effects / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000453:epidemiology; D004724:Endoscopy / Q000592:standards; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology; D006320:Hearing Tests; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000175:diagnosis / Q000453:epidemiology; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis* / Q000453:epidemiology; D010808:Physical Examination / Q000592:standards*; D011014:Pneumonia / Q000175:diagnosis / Q000453:epidemiology; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000453:epidemiology; D011785:Quality Assurance, Health Care / Q000592:standards; D012307:Risk Factors; D014797:Vital Capacity / Q000502:physiology
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents