title: Synthesis of two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids.
abstract: [structures: see text] Two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids, 6-hydroxy-3-methyl-8-(phenylethyl)-2,5-dihydro-1-benzoxepin-9-carboxylic acid (radulanin E) (1) and 9-hydroxy-3-methyl-2,5-dihydro-1-benzoxepin-7-carboxylic acid (2), were synthesized using Stille coupling followed by Mitsunobu cyclization.
authors.affiliation: Department of Chemistry, Faculty of Science, Toyama University, Gofuku, Toyama 930-8555, Japan. seiji@sci.toyama-u.ac.jp
authors.forename: Seiji
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Nao
authors.initials: N
authors.lastname: Tsuchida
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miyazawa
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Hirai
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002264:Carboxylic Acids / Q000138:chemical synthesis*
chemical_list: D002264:Carboxylic Acids