title: [A case of primary hypoparathyroidism and hypothyroidism co-existing with chronic renal failure].
abstract: A case of 24-year old woman with chronic renal failure and primary hypoparathyroidism is presented. Primary hypothyroidism and bilateral hypoacousis were also found. Typically concomitant with chronic renal failure is development of secondary hyperparathyroidism and its co-morbidities, i.e. renal osteodystrophy that consists of osteomalacia, osteoporosis and pathological fractures. In case of some patients with very high concentration of parathormone (PTH) and with signs of renal osteodystrophy, which is the case of tertiary hyperparathyroidism, subtotal parathyroidectomy is the optimal treatment. Reduction of PTH concentration protects bones from further destruction and from accumulation of calcium phosphate in tissues. The accompanying primary parathyroid failure would probably protect from the further consequences of PTH over-production--renal osteodystrophy. The case is reported in view of a rare occurrence of such co-existence, lack of its description in Polish literature as well as diagnostic difficulties.
authors.affiliation: Katedra i Klinika Endokrynologii i Diabetologii Akademii Medycznej im. Piastów Slaskich, Wrocławiu.
authors.forename: Grazyna
authors.initials: G
authors.lastname: Bednarek-Tupikowska
authors.forename: Justyna
authors.initials: J
authors.lastname: Kuliczkowska
authors.forename: Alicja
authors.initials: A
authors.lastname: Filus
mesh_terms: D000328:Adult; D005260:Female; D006312:Hearing Loss, Bilateral / Q000150:complications; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications*; D007037:Hypothyroidism / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000150:complications*; D010281:Parathyroid Hormone / Q000097:blood*
chemical_list: D010281:Parathyroid Hormone