title: [The effect of chromatin remodeling and modification on RNA-polymerase-mediated transcription initiation].
abstract: As eukaryotes are characterized by the presence of chromatin (intricately packaged DNA), special mechanisms are required for preparing the DNA template for operation of the transcription machinery. Recently, a close association between the chromatin state and transcription was found and numerous transcription factors modifying the physical and chemical chromatin state were revealed. This review presents a brief description of transcription initiation on the DNA template within chromatin.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Shidlovskiĭ
authors.forename: E N
authors.initials: EN
authors.lastname: Nabirochkina
mesh_terms: D000818:Animals; D042002:Chromatin Assembly and Disassembly; D004247:DNA / Q000378:metabolism; D022041:Euchromatin / Q000378:metabolism*; D006570:Heterochromatin / Q000378:metabolism*; D012319:RNA Polymerase II / Q000378:metabolism*; D013698:Templates, Genetic; D014158:Transcription, Genetic
chemical_list: D022041:Euchromatin; D006570:Heterochromatin; D004247:DNA; D012319:RNA Polymerase II