title: Persistent psychoses in first episode patients.
abstract: This study was carried out to identify characteristics of patients with schizophrenia spectrum disorder who continue to have persistent psychoses (15%) for 2 years after initiation of treatment by comparing them to those who maintained full recovery of positive symptoms (42%) up to 2 years. Compared to those in recovery, significantly more patients with persistent psychoses were single, male, had a higher prevalence of drug abuse and abnormal EEG findings at presentation for treatment. Duration of untreated psychoses or untreated illness did not discriminate between the groups.
authors.affiliation: Prevention and Early Intervention Program for Psychoses (PEPP), London Health Sciences Centre, 392 South Street, London, Ontario, Canada N6A 4G5. maryallen.amaral@lhsc.on.ca
authors.forename: Rahul
authors.initials: R
authors.lastname: Manchanda
authors.forename: Ross M G
authors.initials: RM
authors.lastname: Norman
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Malla
authors.forename: Rajendra
authors.initials: R
authors.lastname: Harricharan
authors.forename: Sandra
authors.initials: S
authors.lastname: Northcott
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011618:Psychotic Disorders / Q000453:epidemiology* / Q000503:physiopathology / Q000517:prevention & control; D012074:Remission Induction; D012559:Schizophrenia / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control; D012720:Severity of Illness Index; D019966:Substance-Related Disorders / Q000453:epidemiology
chemical_list: D014150:Antipsychotic Agents