Acellular allograft dermal matrix for tympanoplasty.
OBJECTIVE
Reconstruction of the tympanic membrane is a common procedure in otology today. Many different materials have been used for this purpose, including a wide array of autologous tissues. This article focuses on the use of human acellular allograft dermal matrix (AlloDerm, LifeCell Corporation, Branchburg, New Jersey) in tympanoplasty.


RESULTS
The choice of graft materials has expanded to include human dermal allograft tissue. Recent reports show promising results for AlloDerm reconstruction of the tympanic membrane, including animal experiments and in humans.


CONCLUSIONS
AlloDerm has become an acceptable alternative to the use of autologous tissues in tympanic membrane surgery, particularly in type I tympanoplasty. This paper discusses the recent literature on the topic, outlines the authors' experience with the use of AlloDerm, and describes the authors' operative technique.
Haynes
David S
DS
Department of Otolaryngology, The Otology Group of Vanderbilt, Vanderbilt University Medical Center, Nashville, TN 37232, USA. david.haynes@vanderbilt.edu
Vos
Jeremy D
JD
Labadie
Robert F
RF
D003094:Collagen / Q000627:therapeutic use*; D006801:Humans; D018579:Patient Selection; D016896:Treatment Outcome; D014433:Tympanoplasty / Q000379:methods*
C440568:Alloderm; D003094:Collagen