title: Infectious keratitis related to overnight orthokeratology.
abstract: OBJECTIVE
  To report the microbial culture results, clinical course, and visual outcomes for infectious keratitis related to overnight orthokeratology.
  
  
  METHODS
  The records of patients with infectious keratitis related to overnight orthokeratology who presented to a tertiary referral center from April 2000 to March 2003 were retrospectively reviewed.
  
  
  RESULTS
  Twenty patients (21 eyes) were included; 1 patient had bilateral infections. The average age of the patients was 14 years. The average period between the time the patient started the overnight orthokeratology program and the onset of infectious keratitis was 23 months. Thirteen of the 21 eyes were culture positive. Organisms cultured were Pseudomonas aeruginosa (n = 9), coagulase-negative Staphylococcus species (n = 2), Serratia marcescens (n = 1), and Acathamoeba species (n = 1). All patients responded well to medical antimicrobial treatment. Final best spectacle-corrected visual acuity ranged from 20/20 to 20/100.
  
  
  CONCLUSIONS
  Infectious keratitis is a potential complication of overnight orthokeratology that may cause significant visual impairment. Parents of children who consider overnight orthokeratology should evaluate the benefit of temporary myopia reduction and the risk of infection.
authors.affiliation: Department of Ophthalmology, Chang Gung Memorial Hospital, No. 199, Tung Hwa North Road, Taipei, Taiwan, Republic of China.
authors.forename: Ching-Hsi
authors.initials: CH
authors.lastname: Hsiao
authors.forename: Hsin-Chiung
authors.initials: HC
authors.lastname: Lin
authors.forename: Yeong-Fong
authors.initials: YF
authors.lastname: Chen
authors.forename: David H K
authors.initials: DH
authors.lastname: Ma
authors.forename: Lung-Kun
authors.initials: LK
authors.lastname: Yeh
authors.forename: Hsin-Yuan
authors.initials: HY
authors.lastname: Tan
authors.forename: Samuel C M
authors.initials: SC
authors.lastname: Huang
authors.forename: Ken-Kuo
authors.initials: KK
authors.lastname: Lin
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification; D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D002648:Child; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology / Q000469:parasitology; D003320:Corneal Ulcer / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D000981:Antiprotozoal Agents