[Effects of different light-dark cycles on total and differential leukocyte counts as well as spontaneous locomotor activity in mice].
OBJECTIVE
To investigate the effect of different light-dark cycles on total and differential counts of leukocyte as well as spontaneous locomotor activity in mice.


METHODS
144 ICR mice were raised under different light-dark cycles including LD 7 h/7 h, LD 12 h/12 h and LD 16 h/16 h for 8 weeks. Blood samples were obtained by enucleation of eye for total and differential counts of leukocyte. Another 9 mice were also divided into 3 groups and fed under same conditions as above. Their activities were recorded continuously.


RESULTS
The change of spontaneous locomotor activity and leukocyte count were synchronized with the light-dark cycle.


CONCLUSIONS
Different light-dark cycles can influence not only the spontaneous locomotor activity, but also total and differential leukocyte counts in mice.
Guo
Li
L
Liu
Yan-you
YY
Yang
Bo
B
Jiang
Zhou
Z
Wang
Yue-qi
YQ
Wang
Zheng-rong
ZR
D000818:Animals; D001522:Behavior, Animal / Q000528:radiation effects*; D003624:Darkness; D007958:Leukocyte Count; D007962:Leukocytes / Q000528:radiation effects*; D008027:Light; D051379:Mice; D008813:Mice, Inbred ICR; D009043:Motor Activity; D017440:Photoperiod