title: Rufuslactone, a new antifungal sesquiterpene from the fruiting bodies of the basidiomycete Lactarius rufus.
abstract: A new lactarane sesquiterpene, rufuslactone (1), was isolated from the fruiting bodies of the basidiomycete Lactarius rufus. Rufuslactone (1) is an isomer of a previously described lactarane 3,8-oxa-13-hydroxylactar-6-en-5-oic acid gamma-lactone (2) from Lactarius necatar. Its structure,was elucidated on the basis of spectroscopic data. Rufuslactone (1) showed antifungal properties against plant pathogenic fungi.
authors.affiliation: Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming 650204, China.
authors.forename: Du-Qiang
authors.initials: DQ
authors.lastname: Luo
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Bian
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001487:Basidiomycota; D005658:Fungi / Q000187:drug effects; D007536:Isomerism; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000935:Antifungal Agents; D007783:Lactones; D012717:Sesquiterpenes; C504132:rufuslactone