Supercapacitive admittance tomoscopy.
A sensor for measuring adsorption on a substrate has been designed including a contactless detection scheme, called supercapacitive admittance tomoscopy (SCAT). The sensor comprises a thin dielectric layer with two parallel band electrodes on the one side and a chemically modified surface on the other onto which the adsorption of molecules occurs. Upon application of a high frequency ac voltage between the two electrodes, a capacitive coupling is established across the dielectric layer, and the admittance measured depends on the surface state of the chemically modified interface. On the basis of this principle, a flow sensor has been developed to measure sensorgrams to follow the dynamics of the adsorption and has been tested for the adsorption of IgG on the modified surface.
Gamby
Jean
J
Laboratoire d'Electrochimie Physique et Analytique, Ecole Polytechnique Fédérale de Lausanne, CH 1015 Lausanne, Switzerland.
Abid
Jean-Pierre
JP
Girault
Hubert H
HH
D000327:Adsorption; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D004867:Equipment Design; D007074:Immunoglobulin G / Q000737:chemistry; D011093:Polyethylene Terephthalates / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors; D014056:Tomography, X-Ray / Q000295:instrumentation* / Q000379:methods
D007074:Immunoglobulin G; D011093:Polyethylene Terephthalates