title: Screening the SPO11 and EIF5A2 genes in a population of infertile men.
abstract: Populations of infertile and fertile men were screened for mutations in SPO11 and EIF5A2, two infertility candidate genes. Three heterozygous amino acid changes that might contribute to infertility were identified in the infertile group.
authors.affiliation: University of Utah School of Medicine, Salt Lake City, Utah, USA.
authors.forename: Greg L
authors.initials: GL
authors.lastname: Christensen
authors.forename: Ivaylo P
authors.initials: IP
authors.lastname: Ivanov
authors.forename: John F
authors.initials: JF
authors.lastname: Atkins
authors.forename: Anna
authors.initials: A
authors.lastname: Mielnik
authors.forename: Peter N
authors.initials: PN
authors.lastname: Schlegel
authors.forename: Douglas T
authors.initials: DT
authors.lastname: Carrell
mesh_terms: D004706:Endodeoxyribonucleases; D004950:Esterases / Q000235:genetics*; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D009154:Mutation; D010448:Peptide Initiation Factors / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000235:genetics*; D000097574:Eukaryotic Translation Initiation Factor 5A; D000099257:Meiotic Recombination Protein SPO11
chemical_list: D004706:Endodeoxyribonucleases; D004950:Esterases; D010448:Peptide Initiation Factors; D016601:RNA-Binding Proteins; D000097574:Eukaryotic Translation Initiation Factor 5A; D000099257:Meiotic Recombination Protein SPO11