Soybean foods and their benefits: potential mechanisms of action.
Isoflavones have been proposed to be the active component responsible for the beneficial effects of soybean foods, and appear to work in conjunction with the proteins to protect against cancer, cardiovascular disease, and osteoporosis. Most of the research activities on the benefits of soybean foods have focused on the role these isoflavones play in disease prevention or treatment; however, there is also some evidence that the benefits are attributable to certain peptides or protein fractions from soybeans. This review will focus on some of the potential mechanisms whereby soybeans exert their protective effects against heart disease, cancer, and osteoporosis.
Omoni
Adetayo O
AO
Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Aluko
Rotimi E
RE
D000818:Animals; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007529:Isoflavones / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D008297:Male; D009369:Neoplasms / Q000517:prevention & control*; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D045730:Soy Foods / Q000032:analysis
D007529:Isoflavones