Colonic angiomyolipoma with a monotypic expression and a predominant epithelioid component.
Angiomyolipomas are rare lesions, often arising in the kidney, and are part of a group of tumours with a diverse appearance and evidence of dual melanocytic and smooth muscle differentiation known as PEComas (tumours of perivascular epithelioid cell origin). This report describes an unusual case of a colonic PEComa in a 40 year old woman. Unlike most of the previous colonic angiomyolipomas/PEComas reported in the literature, this case formed a large, mainly extrinsic mass and was monotypic, and composed entirely of the myomatous component with no adipose tissue or typical vasculature.
Abdulkader
M
M
Queens Medical Centre University Hospital, Nottingham NG7 2UH, UK.
Abercrombie
J
J
McCulloch
T A
TA
Kaye
P V
PV
D000328:Adult; D018207:Angiomyolipoma / Q000473:pathology / Q000648:ultrastructure*; D002430:Cecal Neoplasms / Q000473:pathology / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness