title: [Use of rifabutin in cases of toxicity to rifampicin].
abstract: Rifampicin is an essential drug in the present treatment of tuberculosis. On some occasions, it cannot be used due to severe adverse effects. Rifabutin is a drug of the same family, with a similar activity and difference adverse effects. This study describes the beneficial results of the substitution of rifampicin with rifabutin in patients with severe toxicity.
authors.affiliation: Medicina Familiar y Salud Comunitaria Area 5, Madrid.
authors.forename: B
authors.initials: B
authors.lastname: Moreno González
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez Blanco
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez Barrientos
authors.forename: J L
authors.initials: JL
authors.lastname: Vidal Pérez
authors.forename: A
authors.initials: A
authors.lastname: Noguerado Asensio
mesh_terms: D000328:Adult; D000368:Aged; D000904:Antibiotics, Antitubercular / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017828:Rifabutin / Q000627:therapeutic use*; D012293:Rifampin / Q000009:adverse effects*; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000904:Antibiotics, Antitubercular; D017828:Rifabutin; D012293:Rifampin