Serum concentration of AMDL DR-70 for the diagnosis and prognosis of carcinoma of the tongue.
The aim of this study was to discover the clinical value of the tumour marker AMDL DR-70 in a group of patients with cancer of the tongue. Serum concentrations of AMDL DR-70 were estimated by enzyme linked immuno-sorbent assay in 52 patients with carcinoma of the tongue and compared with 40 controls and 42 patients with benign lesions in the tongue. Thirty-nine patients with carcinoma of the tongue had results above 6 mg/L (75%), compared with 3/40 (7%) in healthy controls and 4/42 (10%) in those with benign tumours. The concentration of AMDL DR-70 in serum correlated significantly with 3-year survival.
Li
Xiaodan
X
Department of Oral Maxillofacial Surgery, College of Stomatology, Wuhan University, Key Laboratory for Oral Biomedical Engineering, Ministry of Education, Wuhan, Hubei 430079, PR China.
Qiao
Zhi
Z
Long
Xing
X
Wei
Jinxiong
J
Cheng
Yong
Y
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis* / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000175:diagnosis*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D005340:Fibrinogen / Q000032:analysis*; D005350:Fibroma / Q000097:blood; D005500:Follow-Up Studies; D006391:Hemangioma / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009455:Neurofibroma / Q000097:blood; D011379:Prognosis; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D015996:Survival Rate; D014062:Tongue Neoplasms / Q000097:blood / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D005338:Fibrin Fibrinogen Degradation Products; D011933:Reagent Kits, Diagnostic; D005340:Fibrinogen