title: Baboon as a nonhuman primate model for vaccine studies.
abstract: Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.
authors.affiliation: Department of Virology and Immunology, Southwest Foundation for Biomedical Research, 7620 N.W. Loop 410, Military Drive, San Antonio, TX 78227 5301, USA.
authors.forename: Krishna K
authors.initials: KK
authors.lastname: Murthy
authors.forename: Mary T
authors.initials: MT
authors.lastname: Salas
authors.forename: Kenneth D
authors.initials: KD
authors.lastname: Carey
authors.forename: Jean L
authors.initials: JL
authors.lastname: Patterson
mesh_terms: D000818:Animals; D023421:Models, Animal; D010215:Papio; D014612:Vaccines / Q000008:administration & dosage* / Q000145:classification / Q000276:immunology
chemical_list: D014612:Vaccines