[Intensive care for severe acute pneumonia using hemodynamic pulmonary circulatory unloading].
Pulmonary hypertension (PH) and its direct sequel, namely progressive arterial hypoxemia, is one of the severe complications of acute severe pneumonia (ASP). The paper presents the view of the pathogenesis of PH in patients with ASP and discusses a treatment for this complication. Based on the results of their own studies, the authors propose one of the effective methods for decreasing pulmonary vascular resistance. This method is based on the vasoconstrictor concept of the pathogenesis of PH in PH and includes therapy with nitrates. The authors propose to use drugs ameliorating pulmonary arterial hypertension, particularly intravenous nitrates in a dose of 0.2-0.3 mg/kg/day, as a part of intensive care.
Stoliarova
N A
NA
Sadchikova
G D
GD
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy; D003422:Critical Care / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D011652:Pulmonary Circulation / Q000502:physiology*; D012720:Severity of Illness Index