Meroterpenes from the ascidian Aplidium aff. densum.
Chemical investigation of the ascidian Aplidium aff. densum collected at Masirah Island, Oman, has resulted in the isolation of five meroterpenes: two new ones, methoxyconidiol (1) and didehydroconicol (2), and three related, known compounds, 3-5. The structures of 1 and 2 were determined by a combination of mass spectrometry and one- and two-dimensional high-field NMR techniques. Their biological activities against bacteria and human lymphoblastic cell lines were evaluated.
Simon-Levert
Annabel
A
Laboratoire de Chimie des Biomolécules et de l'Environnement and Laboratoire de Biologie Physico-Chimique des Systèmes Intégrés, Université de Perpignan, 52 Avenue Paul Alduy, 66860 Perpignan Cedex, France.
Arrault
Alban
A
Bontemps-Subielos
Nataly
N
Canal
Christophe
C
Banaigs
Bernard
B
D000818:Animals; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D016982:Micrococcus luteus / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009850:Oman; D013210:Staphylococcus / Q000187:drug effects; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D014561:Urochordata / Q000737:chemistry*
D013729:Terpenes