title: Fatal HHV-6 associated encephalitis in an HIV-1 infected patient treated with cidofovir.
abstract: We describe the case of a patient infected with HIV and a concomitant HHV-6 encephalitis. The patient experienced virological failure following cidofovir treatment. RT-PCR was used both for early diagnosis and follow-up.
authors.affiliation: Department of Infectious Diseases, Pitié-Salpêtrière Hospital, 47-83 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.
authors.forename: Myrto
authors.initials: M
authors.lastname: Astriti
authors.forename: Valérie
authors.initials: V
authors.lastname: Zeller
authors.forename: David
authors.initials: D
authors.lastname: Boutolleau
authors.forename: Agnès
authors.initials: A
authors.lastname: Gautheret-Dejean
authors.forename: George
authors.initials: G
authors.lastname: Allen
authors.forename: Danielle
authors.initials: D
authors.lastname: Seilhean
authors.forename: Henri
authors.initials: H
authors.lastname: Agut
authors.forename: François
authors.initials: F
authors.lastname: Bricaire
authors.forename: Christine
authors.initials: C
authors.lastname: Katlama
authors.forename: Philippe
authors.initials: P
authors.lastname: Bossi
mesh_terms: D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001706:Biopsy; D001921:Brain / Q000473:pathology / Q000821:virology; D000077404:Cidofovir; D003596:Cytosine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D018792:Encephalitis, Viral / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D063065:Organophosphonates / Q000009:adverse effects / Q000627:therapeutic use*; D016133:Polymerase Chain Reaction; D019349:Roseolovirus Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D019562:Viral Load
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; D003596:Cytosine; D000077404:Cidofovir