title: PA-457, new kind of antiretroviral: ten-day clinical trial results.
abstract: A new kind of antiretroviral, called a maturation inhibitor, worked well in reducing viral load in a ten-day trial with HIV-positive volunteers.
authors.forename: John S
authors.initials: JS
authors.lastname: James
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D017277:Drug Approval; D010919:Placebos; D013386:Succinates / Q000627:therapeutic use*; D014315:Triterpenes / Q000627:therapeutic use*; D014481:United States; D014486:United States Food and Drug Administration; D053978:Pentacyclic Triterpenes
chemical_list: D019380:Anti-HIV Agents; D010919:Placebos; D013386:Succinates; D014315:Triterpenes; C479935:bevirimat; D053978:Pentacyclic Triterpenes