Case report: Malignant peripheral nerve sheath tumor of the uterine cervix treated with radical vaginal trachelectomy.
BACKGROUND
Malignant peripheral nerve sheath tumors (MPNST) are rare tumors which occur primarily in major nerve trunks and most commonly in patients with neurofibromatosis. Only seven prior cases of these tumors arising in the uterine cervix have been reported, all of which were treated by hysterectomy.


METHODS
We report a 22-year-old woman with MPNST of the uterine cervix which recurred after loop electrocautery excision and had positive margins on cone biopsy. She was treated definitively with radical trachelectomy and is well with no sign of recurrence 20 months later.


CONCLUSIONS
MPNST of the uterine cervix is a rare, but potentially aggressive neoplasm. This is the first case of such a tumor treated successfully with preservation of the patients fertility.
Rodriguez
Anne O
AO
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of California, Davis Medical Center, 4860 Y Street, Suite 2500, Sacramento, CA 95817, USA. anne.rodriguez@ucdmc.ucdavis.edu
Truskinovsky
Alexander M
AM
Kasrazadeh
Monica
M
Leiserowitz
Gary S
GS
D000328:Adult; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D018317:Nerve Sheath Neoplasms / Q000473:pathology / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*