Application of the lattice Boltzmann model to simulated stenosis growth in a two-dimensional carotid artery.
The lattice Boltzmann model is used to observe changes in the velocity flow and shear stress in a carotid artery model during a simulated stenosis growth. Near wall shear stress in the unstenosed artery is found to agree with literature values. The model also shows regions of low velocity, rotational flow and low near wall shear stress along parts of the walls of the carotid artery that have been identified as being prone to atherosclerosis. These regions persist during the simulated stenosis growth, suggesting that atherosclerotic plaque build-up creates regions of flow with properties that favour atherosclerotic progression.
Boyd
J
J
Biophysical and Biomedical Research Group, School of Biological, Biomedical and Molecular Sciences, University of New England, Armidale, NSW, 2351, Australia. jobyd3@pobox.une.edu.au
Buick
J
J
Cosgrove
J A
JA
Stansell
P
P
D000818:Animals; D001161:Arteriosclerosis / Q000150:complications* / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002339:Carotid Arteries / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000209:etiology* / Q000503:physiopathology*; D003198:Computer Simulation; D018450:Disease Progression; D006801:Humans; D008955:Models, Cardiovascular