title: Photocurable hard and porous biomaterials from ROMP precursors cross-linked with diyl radicals.
abstract: A combination of (ROMP) ring-opening metathesis polymerization and diradical (diyl) cross-linking provides a new access to hard biomaterials and potential artificial bone replacements. ROMP was used to construct soft and pliable linear polymers bearing photolabile diazene functions. After treatment with light, a nitrogen aerosol is released throughout the polymer to create desirable porosity, cross-linking, and hardening in a single step. Nonpolymeric mechanistic work supporting these studies was also examined.
authors.affiliation: Department of Chemistry, University of Florida, Gainesville, FL 32611, USA. enholm@chem.ufl.edu
authors.forename: Eric
authors.initials: E
authors.lastname: Enholm
authors.forename: Aarti
authors.initials: A
authors.lastname: Joshi
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Wright
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D005740:Gases / Q000737:chemistry; D007094:Imides / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D010782:Photolysis; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D016062:Porosity
chemical_list: D001672:Biocompatible Materials; D005740:Gases; D007094:Imides; D011108:Polymers; C038867:diazene; D009584:Nitrogen