title: Epstein-Barr virus related opsoclonus-myoclonus-ataxia does not rule out the presence of occult neuroblastic tumors.
abstract: Opsoclonus-myoclonus-ataxia (OMA) secondary to Epstein-Barr virus (EBV) infection has only been described in three pediatric patients. Previous reports suggested that evidence for a recent EBV infection in the absence of an occult neoplasm would predict a favorable prognosis for OMA as well as no tumor development. We present the case of a 20-month-old child with OMA associated with a microbiologically documented acute EBV infection and an occult thoracic ganglioneuroblastoma diagnosed 5 months later.
authors.affiliation: Department of Pediatrics, Unitat Integrada Hospital Sant Joan de Déu-Hospital Clínic. University of Barcelona, Barcelona, Spain.
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Cardesa-Salzmann
authors.forename: Jaume
authors.initials: J
authors.lastname: Mora
authors.forename: M Angels
authors.initials: MA
authors.lastname: García Cazorla
authors.forename: Ofelia
authors.initials: O
authors.lastname: Cruz
authors.forename: Carmen
authors.initials: C
authors.lastname: Muñoz
authors.forename: Jaume
authors.initials: J
authors.lastname: Campistol
mesh_terms: D020031:Epstein-Barr Virus Infections / Q000150:complications*; D005260:Female; D018305:Ganglioneuroblastoma / Q000150:complications*; D006801:Humans; D007223:Infant; D053578:Opsoclonus-Myoclonus Syndrome / Q000209:etiology*; D013899:Thoracic Neoplasms / Q000150:complications*