title: Asbestos exposure and cancer mortality among petroleum refinery workers: a Poisson regression analysis of updated data.
abstract: The authors investigated the relationship between asbestos exposure and respiratory cancer mortality among maintenance workers and other blue-collar workers at an Italian oil refinery. The cohort contained 931 men, 29,511 person-years, and 489 deaths. Poisson regression analysis using white-collar workers as an internal referent group provided relative risk estimates (RRs) for main causes of death, adjusted for age, age at hiring, calendar period, length of exposure, and latency. Among maintenance workers, RRs for all tumors (RR = 1.50), digestive system cancers (RR = 1.41), lung cancers (RR = 1.53), and nonmalignant respiratory diseases (RR = 1.71) were significantly increased (p < 0.05); no significant excess was found for all causes and among maintenance (RR = 1.12) and other blue-collar workers (RR = 1.01). Results confirm the increased risk of death from respiratory diseases and cancer among maintenance workers exposed to asbestos, whereas other smoking-related diseases (circulatory system) were not statistically different among groups.
authors.affiliation: Epidemiology and Biostatistics, National Cancer Research Institute, Genoa, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Montanaro
authors.forename: Marcello
authors.initials: M
authors.lastname: Ceppi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Puntoni
authors.forename: Stefania
authors.initials: S
authors.lastname: Silvano
authors.forename: Valerio
authors.initials: V
authors.lastname: Gennaro
mesh_terms: D000328:Adult; D000368:Aged; D001194:Asbestos / Q000506:poisoning*; D015331:Cohort Studies; D006801:Humans; D007221:Industry; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology* / Q000401:mortality*; D016273:Occupational Exposure; D010578:Petroleum; D012044:Regression Analysis; D012140:Respiratory Tract Diseases / Q000209:etiology* / Q000401:mortality*
chemical_list: D010578:Petroleum; D001194:Asbestos