title: Population genetic analysis of 15 autosomal STRs loci in the central region of Argentina.
abstract: Allele frequencies, together with some parameters of forensic interest, for 15 STRs included in the Powerplex-16 System (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, TH01, TPOX and VWA) were estimated from a sample set of 1368 unrelated individuals from three of the most densely populated provinces of Argentina. No deviations from Hardy-Weinberg equilibrium were observed using the Bonferroni correction for the number of loci analyzed. Comparative analyses between our population data and that of other Argentinean databases previously published are presented and discussed. The most informative loci in our data set is the Penta E Loci with discrimination power larger than 0.98 and typical paternity index larger than 4.3. Our results demonstrate that these loci are robust since different laboratories and sample sets provided highly consistent results. This observation underscores the usefulness of these markers systems for human identification and parentage testing.
authors.affiliation: Servicio de Huellas Digitales Genéticas and Cátedra de Genética y Biología Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 1113 Buenos Aires, Argentina.
authors.forename: Miguel
authors.initials: M
authors.lastname: Marino
authors.forename: Andrea
authors.initials: A
authors.lastname: Sala
authors.forename: Daniel
authors.initials: D
authors.lastname: Corach
mesh_terms: D001118:Argentina; D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences