Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements.
Template-directed single nucleotide extension of an RNA primer with oxyazabenzotriazolides of ribonucleotides is shown to be fast and sequence-selective; downstream-binding RNA strands contribute to the acceleration of the reaction.
Vogel
Stephanie R
SR
Institute for Organic Chemistry, University of Karlsruhe (TH), 76131 Karlsruhe, Germany.
Deck
Christopher
C
Richert
Clemens
C
D001483:Base Sequence; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008969:Molecular Sequence Data; D012313:RNA / Q000138:chemical synthesis* / Q000737:chemistry*; D012265:Ribonucleotides / Q000737:chemistry*; D013696:Temperature
D012265:Ribonucleotides; D012313:RNA