[A systematic review of diagnosis of Helicobacter pylori infection by Helicobacter pylori stool antigen test].
OBJECTIVE
To evaluate the accuracy of Helicobacter pylori (Hp) stool antigen test for diagnosing Hp infection.


METHODS
Articles related to diagnosis of Hp infection by Hp stool antigen test, published before March 2004, were retrieved in the databanks such as CBMdisc, CMCC, CNKI, and VIP. Related journals were searched manually. Meta-analysis was performed by SROC curve recommended by Diagnostic and Screening Group of the Cochrane Collaboration Web with the parameters such as sensitivity, specificity, accuracy, predictive values, and likelihood ratio.


RESULTS
In total 19 studies including 3123 patients met the inclusion criteria. The sensitivity of Hp stool antigen for the diagnosis of Hp infection was 94% and its specificity was 93%.


CONCLUSIONS
Helicobacter pylori stool antigen examination is a simple, noninvasive and highly accurate method in diagnosis of Hp infection.
Guo
Yin-yan
YY
Department of Digest, Beijing Haidian Hospital, Beijing 100080, China.
Zhang
Shu-tian
ST
Peng
Xiao-xia
XX
Zhan
Si-yan
SY
D000942:Antigens, Bacterial / Q000032:analysis*; D005243:Feces / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial