title: Coronary surgery in dialysis-dependent patients with end stage renal failure.
abstract: The number of patients with dialysis-dependent end stage renal failure (ESRF) and coronary heart disease (CAD) has increased in recent years. Coronary artery bypass grafting (CABG) has become the standard treatment for CAD in this patient group, but is still considered as a risk procedure due to increased mortality and morbidity. In a retrospective study we analyzed our clinical results of isolated CABG in 40 dialysis-dependent patients with ESRF (5 female and 35 male, mean age 65+/-8.4 years) and the use of extracorporeal circulation. The perioperative control group comprised 51 patients (10 female and 41 male, mean age 67+/-7.3 years) with normal renal function and isolated CABG. Demographic and preoperative data were comparable in both groups. Hospital mortality was 2.5% in patients with ESRF and 0% in patients with normal renal function. Morbidity was comparable in both groups. The mean number of grafts was 3.1+/-0.9 in the dialysis group and 2.9+/-0.8 in the control group. In the follow-up of the dialysis group (34+/-23 months) 8 patients died. CABG in patients with dialysis-dependent ESRF can be performed with good clinical results and morbidity comparable to patients with normal renal function.
authors.affiliation: Dept. of Cardiac Surgery, Heart Center Dresden University Hospital, Fetscherstr. 76, 01307, Dresden, Germany. M.Weber@herzzentrum-dresden.com
authors.forename: S M
authors.initials: SM
authors.lastname: Tugtekin
authors.forename: K
authors.initials: K
authors.lastname: Alexiou
authors.forename: Ch
authors.initials: Ch
authors.lastname: Georgi
authors.forename: U
authors.initials: U
authors.lastname: Kappert
authors.forename: M
authors.initials: M
authors.lastname: Knaut
authors.forename: K
authors.initials: K
authors.lastname: Matschke
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality*; D005112:Extracorporeal Circulation / Q000401:mortality*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality* / Q000534:rehabilitation*; D008297:Male; D015995:Prevalence; D006435:Renal Dialysis / Q000401:mortality*; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016896:Treatment Outcome