The longest micron; transporting poxviruses out of the cell.
The large size of poxvirus virions (approximately 250-300 microm) makes them dependent on active transport for intracellular movement during infection. Several recent papers have reported the utilization of the microtubule network by poxviruses during viral egress and their use of conventional kinesin for intracellular transport. This review looks at recent reports of poxvirus intracellular transport for virion egress and their interaction with the microtubule network.
Ward
Brian M
BM
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA. Brian_Ward@urmc.rochester.edu
D006801:Humans; D016547:Kinesins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism*; D018155:Orthopoxvirus / Q000502:physiology* / Q000648:ultrastructure; D014771:Virion / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure
D016547:Kinesins