title: Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1-year prospective study.
abstract: To determine whether children have persistent abnormalities in cellular and humoral immunity development after acute Mycoplasma pneumoniae infection, serum immunoglobulin G (IgG), IgA, IgM, and IgE levels and lymphocyte phenotypes were determined. There were no changes in the levels of IgG, IgM, IgA, or CD4+ or CD19+ lymphocytes that were measured in M. pneumoniae-positive patients after 3 months or after 12 months, but there were increases in these in M. pneumoniae-negative patients. Serum IgE increased in M. pneumoniae-positive patients. We have shown alterations in immunity development after M. pneumoniae infection.
authors.affiliation: M. Curie Hospital, Department of Pediatrics and Allergy, 35 Parzeczewska Str., 95-100 Zgierz, Poland. interna@wss.zgierz.pl
authors.forename: Iwona
authors.initials: I
authors.lastname: Stelmach
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Podsiadłowicz-Borzecka
authors.forename: Tomasz
authors.initials: T
authors.lastname: Grzelewski
authors.forename: Pawel
authors.initials: P
authors.lastname: Majak
authors.forename: Wlodzimierz
authors.initials: W
authors.lastname: Stelmach
authors.forename: Joanna
authors.initials: J
authors.lastname: Jerzyńska
authors.forename: Marta
authors.initials: M
authors.lastname: Popławska
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Dziadek
mesh_terms: D000917:Antibody Formation; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007107:Immune System / Q000382:microbiology; D007111:Immunity, Cellular; D007132:Immunoglobulin Isotypes / Q000097:blood; D016130:Immunophenotyping; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D011019:Pneumonia, Mycoplasma / Q000276:immunology*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D007132:Immunoglobulin Isotypes