title: Primary angiosarcoma of the lung.
abstract: Primary angiosarcoma of the lung is a rare disorder with few cases reported in the literature [Patel AM, Ryu JH. Angiosarcoma in the lung. Chest 1993;103:1531-35]. We present a case of primary angiosarcoma of the lung in a 79-year-old woman. Preoperative computed tomographic scan revealed soft tissue nodules surrounded by a halo of ground-glass attenuation, an appearance consistent with hemorrhagic pulmonary nodules [Primack S, Hartman T, Lee KS. Pulmonary nodules and the CT halo sign. Radiology 1994;190:513-15]. Lung biopsy revealed a multifocal malignant neoplasm with areas of hemorrhage. The histologic, cytologic, and immunophenotypic features were characteristic of epithelioid angiosarcoma. This case report contributes to the sparse literature on this disease and provides computed tomographic and pathologic correlation in a patient with hemorrhagic pulmonary nodules.
authors.affiliation: Department of Radiology, Hospital of Saint Raphael, New Haven, CT 06511, USA.
authors.forename: Sameer A
authors.initials: SA
authors.lastname: Pandit
authors.forename: Paul N
authors.initials: PN
authors.lastname: Fiedler
authors.forename: Jack L
authors.initials: JL
authors.lastname: Westcott
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014657:Vasculitis / Q000473:pathology