title: [Trial study on DENG Tie-tao's coronary heart disease capsules in improving patients' quality of life].
abstract: OBJECTIVE
  To assess the efficacy of the Coronary Heart Disease (CHD) Capsules worked out by Prof. Deng --in improving quality of life of CHD patients of qi deficiency with phlegm and blood stasis syndrome.
  
  
  METHODS
  According to the WHO's diagnosis criteria of CHD, a total of 93 stable angina patients were divided into 3 groups using the single blinded method. The groups were evenly distributed into CHD Capsule treated group (CHDC), isosorbide dinitrate control group (ID), and Compound Prescription Danshen Droplet Pills control group (CPDDP). Two courses of treatment lasting for 6 months were given. During the courses of treatment, the following parameters were observed: clinical symptoms of angina pectoris, ECG change, treadmill exercise test, 36 items in short form of health survey (SF-36) and Seattle Angina Questionnaire (SAQ) scale.
  
  
  RESULTS
  After 6 months of treatment, all the three groups showed good curative effect in angina pectoris, ECG and treadmill exercise test, differences between them had no statistical significance. The CHDC group showed a better result in nitro-glycerine stopping or alleviation rate and in improving symptoms than the other groups (P < 0.05). The general health, vitality, role-emotional, mental health and reported health transition in the CHDC group were significantly better than those in the control groups (P < 0.05). The scores in physiological functioning role, physiological function and pain alleviation were not different among the three groups.
  
  
  CONCLUSIONS
  Prof. DENG Tie-tao's CHDC is effective in treating CHD with qi deficiency, phlegm and blood stasis and also in improving the quality of life. CHDC is more suitable to be used in long-term treatment than isosorbide dinitrate. The SF-36 and SAQ can be used to appraise the curative effect of traditional Chinese medicine agents for CHD angina pectoris.
authors.affiliation: Heart Center, Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510120, China. wuhuanlinboshi@yahoo.com.cn
authors.forename: Huan-lin
authors.initials: HL
authors.lastname: Wu
authors.forename: Xia
authors.initials: X
authors.lastname: Wang
authors.forename: Xin-mei
authors.initials: XM
authors.lastname: Li
authors.forename: Wen-jie
authors.initials: WJ
authors.lastname: Luo
authors.forename: Tie-tao
authors.initials: TT
authors.lastname: Deng
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy* / Q000209:etiology; D002214:Capsules; D002317:Cardiovascular Agents; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D008517:Phytotherapy; D028321:Plant Preparations; D011788:Quality of Life; D027561:Salvia miltiorrhiza; D016037:Single-Blind Method; D016896:Treatment Outcome
chemical_list: D002214:Capsules; D002317:Cardiovascular Agents; D004365:Drugs, Chinese Herbal; D028321:Plant Preparations; D007548:Isosorbide Dinitrate