Antibacterial activity of Ocimum sanctum L. fixed oil.
Ocimum sanctum fixed oil showed good antibacterial activity against Staphylococcus aureus, Bacillus pumilus and Pseudomonas aeruginosa, where S. aureus was the most sensitive organism. Sesame and soyabean oils also showed moderate activity against S. aureus. Higher content of linolenic acid in O. sanctum fixed oil could contribute towards its antibacterial activity. The antibacterial activity combined with anti-inflammatory and analgesic activities of the oil, could make it useful in inflammatory disorder resulting from staphylococcal infection.
Singh
Surender
S
Delhi Institute of Pharmaceutical Sciences and Research, University of Delhi, Pushp Vihar, New Delhi 110 017, India.
Malhotra
Manjusha
M
Majumdar
D K
DK
D000890:Anti-Infective Agents / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001407:Bacillus / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D031339:Ocimum / Q000378:metabolism*; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000627:therapeutic use*; D010938:Plant Oils / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000378:metabolism; D013211:Staphylococcus aureus / Q000378:metabolism; D017962:alpha-Linolenic Acid / Q000378:metabolism*
D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D010938:Plant Oils; D017962:alpha-Linolenic Acid