title: Synthesis of bridgehead hydroxy bicyclo[2.2.2]octane derivatives.
abstract: Two independent synthetic routes, starting from 1,3-cyclohexadione, toward the 4-hydroxy bicyclo[2.2.2]octane-2,6-dione derivative 3 are described.
authors.affiliation: Division of Organic Chemistry, Kemicentrum, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.
authors.forename: Viveca
authors.initials: V
authors.lastname: Thornqvist
authors.forename: Sophie
authors.initials: S
authors.lastname: Manner
authors.forename: Magnus
authors.initials: M
authors.lastname: Wingstrand
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Frejd
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009795:Octanes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D009795:Octanes