First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients.
Pilowsky
L S
LS
Bressan
R A
RA
Stone
J M
JM
Erlandsson
K
K
Mulligan
R S
RS
Krystal
J H
JH
Ell
P J
PJ
D000704:Analysis of Variance; D014150:Antipsychotic Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D003024:Clozapine / Q000627:therapeutic use; D007839:Functional Laterality / Q000502:physiology; D020022:Genetic Predisposition to Disease; D006146:Guanidines / Q000378:metabolism; D006624:Hippocampus / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000503:physiopathology; D006801:Humans; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics* / Q000378:metabolism*; D012016:Reference Values; D012559:Schizophrenia / Q000188:drug therapy / Q000378:metabolism* / Q000503:physiopathology; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon
D014150:Antipsychotic Agents; C417904:CNS 1261; D006146:Guanidines; D016194:Receptors, N-Methyl-D-Aspartate; D003024:Clozapine