title: Pericarditis associated with nickel hypersensitivity to the Amplatzer occluder device: a case report.
abstract: A 38-year-old man with a history of migraine headaches with aura and one episode of ischemic stroke was found to have a patent foramen ovale (PFO). After percutaneous closure with the nickel-containing Amplatzer PFO occluder, the patient developed pericarditis, atrial fibrillation, and increased migraine headaches with aura that abated with oral prednisone. He tested positive for nickel hypersensitivity, which we conclude is the likely etiology of his pericarditis.
authors.affiliation: Department of Medicine, Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
authors.forename: Dominic W
authors.initials: DW
authors.lastname: Lai
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Saver
authors.forename: Jesus A
authors.initials: JA
authors.lastname: Araujo
authors.forename: Marc
authors.initials: M
authors.lastname: Reidl
authors.forename: Jonathan
authors.initials: J
authors.lastname: Tobis
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation*; D017548:Echocardiography, Transesophageal; D005938:Glucocorticoids / Q000627:therapeutic use; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D008297:Male; D008881:Migraine Disorders / Q000188:drug therapy / Q000209:etiology; D009532:Nickel / Q000009:adverse effects*; D010493:Pericarditis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D019736:Prostheses and Implants / Q000009:adverse effects*; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*
chemical_list: D005938:Glucocorticoids; D009532:Nickel; D011239:Prednisolone