Prothrombin and intraventricular haemorrhage.
In the study by Salonvaara et al., low prothrombin activity in preterm infants was associated with intraventricular haemorrhage (IVH). The interesting research question-do preterm infants who develop IVH have underlying coagulation disturbance?-could not be answered in this study.


CONCLUSIONS
The association needs further investigation. The role of prothrombin in perinatal brain damage in the development of IVH and of white matter damage has to be further elucidated.
Fellman
Vineta
V
Department of Pediatrics, Lund University, Lund, Sweden. vineta.fellman@pdi.lu.se
D002543:Cerebral Hemorrhage / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D011516:Prothrombin / Q000032:analysis*
D011516:Prothrombin