Rome I criteria are more sensitive than Rome II for diagnosis of irritable bowel syndrome in Indian patients.
OBJECTIVE
To assess the utility and efficacy of Rome I and Rome II criteria for the diagnosis of irritable bowel syndrome (IBS) in India.


METHODS
Patients referred with a diagnosis of IBS by general practitioners answered a questionnaire about clinical features, including those listed in the Rome I and Rome II criteria. All patients underwent investigations to determine the cause of their symptoms. Sensitivity, positive predictive value and percent agreement of final diagnosis with Rome I and II criteria were calculated.


RESULTS
Among 138 patients studied, 6 patients had organic disease . Amongst 132 patients with functional bowel disease, Rome I criteria diagnosed more patients as IBS than Rome II criteria (110 [83.3%] vs. 41 [31.1%]); 36 patients fulfilled both the criteria. Of the patients positive by Rome I, 32.7% fulfilled Rome II criteria, and of those diagnosed by Rome II criteria, 87.8% fulfilled Rome I criteria. Seventeen patients did not fulfill either Rome I or Rome II criteria, and were classified as functional abdominal bloating, functional diarrhea or functional constipation.


CONCLUSIONS
Rome I criteria are more sensitive than Rome II criteria for the diagnosis of IBS in the Indian population.
Banerjee
Rupa
R
Asian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad 500 082, India.
Choung
Ong Wai
OW
Gupta
Rajesh
R
Tandan
Manu
M
Lakhtakia
Sandeep
S
Rao
G V
GV
Reddy
D Nageshwar
DN
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007194:India; D043183:Irritable Bowel Syndrome / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity