title: Vertebrectomy and anterior reconstruction for the treatment of spinal metastases.
abstract: The purpose of this study was to retrospectively analyse the outcome of modular vertebral body replacement in conjunction with vertebrectomy in cancer patients with skeletal metastases. Between 1996 and 2000, we performed vertebrectomy with subsequent implantation of a modular vertebral body replacement in 24 patients with skeletal metastases of the spine. The findings were analysed retrospectively. The mean postoperative survival period for all patients was 15.6 months. Improvement of preoperative back pain was achieved in 85%. Remission of initial neurological symptoms based on the Frankel classification was achieved in 57.1% of the patients. Implant dislocations were not observed during follow-up. Vertebrectomy for vertebral metastasis is indicated in selected patients. Type of underlying malignancy, metastatic spread and adjuvant treatment options are an important basis for the indication. In anterior defect reconstructions, modular implants can directly restore stability while reducing tumour-related symptoms.
authors.affiliation: Department of Orthopaedic Surgery, Georg August University of Göttingen, Germany. ternstberger@med.uni-goettingen.de
authors.forename: Thorsten
authors.initials: T
authors.lastname: Ernstberger
authors.forename: Tanja
authors.initials: T
authors.lastname: Brüning
authors.forename: Friedhelm
authors.initials: F
authors.lastname: König
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000601:surgery*