title: Spontaneous splenic rupture associated with hepatosplenic gammadelta T-cell lymphoma.
abstract: Spontaneous splenic rupture is an uncommon but life-threatening complication of hematologic malignancies, despite the frequent involvement of the spleen in these diseases. It has been reported in patients with acute and chronic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma, and histiocytic lymphoma. A 50-year-old previously healthy man presented with acute symptoms of spontaneous splenic rupture. Emergency splenectomy with liver biopsy was performed. The clinicopathologic features suggested a hepatosplenic gammadelta T-cell lymphoma (HSgammadeltaTL). Here, we report a rare case of spontaneous splenic rupture associated with HSgammadeltaTL, unspecified in the World Health Organization classification.
authors.affiliation: Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Jia-Hui
authors.initials: JH
authors.lastname: Chen
authors.forename: De-Chuan
authors.initials: DC
authors.lastname: Chan
authors.forename: Herng-Sheng
authors.initials: HS
authors.lastname: Lee
authors.forename: Hsiao-Dung
authors.initials: HD
authors.lastname: Liu
authors.forename: Chung-Bao
authors.initials: CB
authors.lastname: Hsieh
authors.forename: Jyh-Cherng
authors.initials: JC
authors.lastname: Yu
authors.forename: Yao-Chi
authors.initials: YC
authors.lastname: Liu
authors.forename: Cheng-Jueng
authors.initials: CJ
authors.lastname: Chen
mesh_terms: D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D016411:Lymphoma, T-Cell, Peripheral / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013160:Splenic Neoplasms / Q000150:complications* / Q000473:pathology; D013161:Splenic Rupture / Q000209:etiology*; D013163:Splenomegaly / Q000209:etiology