title: Is there an association between septate uterus and endometriosis?
abstract: BACKGROUND
  The question of whether Müllerian anomalies are significantly more often combined with endometriosis is a controversially discussed problem. Some publications described this association in patients with obstructive but not non-obstructive Müllerian anomalies or controls without Müllerian anomalies. The aim of this study was to evaluate the incidence of endometriosis in patients with a septate uterus as a non-obstructive form of Müllerian anomalies.
  
  
  METHODS
  In a retrospective study, we evaluated 120 patients (29.4 +/- 4.7 years; mean +/- SD) with a septate uterus. The control group consisted of 486 consecutive infertile patients (30.8 +/- 6.3 years) with a normal hysteroscopy and laparoscopy.
  
  
  RESULTS
  The incidence of dysmenorrhoea was comparable in both groups, but the incidence of endometriosis was significantly higher in patients with a septate uterus (25.8 versus 15.2%, P = 0.006).
  
  
  CONCLUSIONS
  Our results suggest a higher incidence of endometriosis in patients with a septate uterus. If it can be confirmed by others, the initial finding of a septate uterus in infertile patients should be followed by a combined hysteroscopy and laparoscopy.
authors.affiliation: Endokrinologikum Hamburg, Centre for Hormone and Metabolic Diseases, Reproductive Medicine and Gynaecological Endocrinology, University of Cologne, Germany. Frank.Nawroth@Endokrinologikum.com
authors.forename: Frank
authors.initials: F
authors.lastname: Nawroth
authors.forename: Gohar
authors.initials: G
authors.lastname: Rahimi
authors.forename: Claudia
authors.initials: C
authors.lastname: Nawroth
authors.forename: Dolores
authors.initials: D
authors.lastname: Foth
authors.forename: Michael
authors.initials: M
authors.lastname: Ludwig
authors.forename: Torsten
authors.initials: T
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications* / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D012189:Retrospective Studies; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery