title: [Ventilator associated acute lung injury].
abstract: Mechanical ventilation plays a central role in the critical care setting; but its use is closely related with some life threatening complications as nosocomial pneumonia and low cardiac performance. One of the most severe complications is called ventilator-associated lung injury (VALI) and it includes: Barotrauma, volutrauma, atelectrauma, biotrauma and oxygen-mediated toxic effects and it is related with an inflammatory response secondary to the stretching and recruitment process of alveoli within mechanical ventilation. The use of some protective ventilatory strategies has lowered the mortality rate 10% approximately.
authors.affiliation: * División de Medicina Crítica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. tony75ni@msn.com
authors.forename: Silvio Antonio
authors.initials: SA
authors.lastname: Namendys-Silva
authors.forename: Juan Gabriel
authors.initials: JG
authors.lastname: Posadas-Calleja
mesh_terms: D000208:Acute Disease; D000403:Airway Resistance; D000818:Animals; D001469:Barotrauma / Q000209:etiology* / Q000517:prevention & control; D002986:Clinical Trials as Topic; D004108:Dilatation, Pathologic / Q000209:etiology / Q000517:prevention & control; D004548:Elasticity; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D055370:Lung Injury; D018384:Oxidative Stress; D010100:Oxygen / Q000009:adverse effects; D010102:Oxygen Inhalation Therapy / Q000009:adverse effects; D011175:Positive-Pressure Respiration / Q000009:adverse effects; D011312:Pressure / Q000009:adverse effects; D011650:Pulmonary Alveoli / Q000503:physiopathology; D011654:Pulmonary Edema / Q000209:etiology / Q000473:pathology / Q000517:prevention & control; D051381:Rats; D012121:Respiration, Artificial / Q000009:adverse effects* / Q000379:methods; D013314:Stress, Mechanical
chemical_list: D010100:Oxygen