title: Dumping syndrome: pathophysiology and treatment.
abstract: Anatomic and physiologic changes introduced by gastric surgery result in clinically significant dumping syndrome in approximately 10% of patients. Dumping is the effect of alteration in the motor functions of the stomach, including disturbances in the gastric reservoir and transporting function. Gastrointestinal hormones play an important role in dumping by mediating responses to surgical resection. Treatment options of dumping syndrome include diet, medications, and surgical revision. Poor nutrition status can be anticipated in patients who fail conservative therapy. Management of refractory dumping syndrome can be a challenge. This review highlights current knowledge about the mechanisms of dumping syndrome and available therapy.
authors.affiliation: Department of Gasteroenterology, Cleveland Clinic Florida, Weston, FL 33331, USA. uklejaa@ccf.org
authors.forename: Andrew
authors.initials: A
authors.lastname: Ukleja
mesh_terms: D003131:Combined Modality Therapy; D004377:Dumping Syndrome / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D044623:Nutrition Therapy; D009752:Nutritional Status; D012086:Reoperation
chemical_list: D005765:Gastrointestinal Agents