Kinetic resolution of alpha-acetoxy N-acyl oxazolidinethiones by a chiral O-nucleophilic acyl transfer catalyst.
The kinetic resolution of alpha-acetoxy N-acyl oxazolidinethiones using the chiral, nonracemic O-nucleophilic acyl transfer catalyst 8 is described. The reaction proceeds on a variety of substrates in excellent yields, with s-factors ranging from 17 to 31.
Notte
Gregory T
GT
Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215, USA.
Sammakia
Tarek
T
Steel
Peter J
PJ
D002384:Catalysis; D007700:Kinetics; D010080:Oxazoles / Q000737:chemistry*; D013237:Stereoisomerism
D010080:Oxazoles