title: Solitary fibrous tumour of the oral cavity with histological features of aggressiveness.
abstract: We operated on a 65-year-old woman and removed a solitary fibrous tumour from her oral mucosa. Microscopically we found marked atypia, abundant necrosis, increased number of mitotic figures (>4 in 10 high-power fields) and hypercellularity. The tumour cells were strongly stained for CD34. There has been no recurrence after 18 months.
authors.affiliation: Department of Oral & Maxillofacial Surgery, University Hospital La Princesa-Madrid, c/ Diego de León, 62, 28006 Madrid, Spain. raugg@mixmail.com
authors.forename: Raúl
authors.initials: R
authors.lastname: González-García
authors.forename: José L
authors.initials: JL
authors.lastname: Gil-Díez Usandizaga
authors.forename: Syong
authors.initials: S
authors.lastname: Hyun Nam
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Rodríguez Campo
authors.forename: Luis
authors.initials: L
authors.lastname: Naval-Gías
mesh_terms: D000071443:12E7 Antigen; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D015815:Cell Adhesion Molecules / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008940:Mitotic Index; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery; D009336:Necrosis; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D014746:Vimentin / Q000032:analysis
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; D018952:Antigens, CD34; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D019253:Proto-Oncogene Proteins c-bcl-2; D014746:Vimentin