title: [A case of recurrent breast cancer causing malignant pericardial effusion successfully managed with instillations of cisplatin].
abstract: A 44-year-old female patient was admitted to our hospital because of dyspnea caused by malignant cardiac tamponade 2 years and 8 months after standard radical mastectomy for a stage III breast cancer. Malignant pericardial effusion was diagnosed by echocardiography and differentiated by cytology. Pericardiocentesis improved her hemodynamics and 9 consecutive pericardial instillations of cisplatin (10 mg) prevented reaccumulation of pericardial effusion, which had never reoccurred until she died of breast cancer one year and 6 months later. Therefore, it is suggested that instillation of cisplatin is one of the beneficial alternatives to surgical treatment.
authors.affiliation: Dept. of Tumor Surgery, Kochi Medical School.
authors.forename: Takeki
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Michiya
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Takehiro
authors.initials: T
authors.lastname: Okabayashi
authors.forename: Norihiro
authors.initials: N
authors.lastname: Hokimoto
authors.forename: Hideaki
authors.initials: H
authors.lastname: Nishimori
authors.forename: Fumiyasu
authors.initials: F
authors.lastname: Yamasaki
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Moriki
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Takahashi
authors.forename: Shiro
authors.initials: S
authors.lastname: Sasaguri
authors.forename: Keijiro
authors.initials: K
authors.lastname: Araki
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage*; D005260:Female; D006338:Heart Neoplasms / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D015409:Mastectomy, Radical; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D020519:Pericardiocentesis; D010496:Pericardium; D011788:Quality of Life; D055502:Secondary Prevention; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin