title: Confirmation of quantitative trait loci affecting fatness in chickens.
abstract: In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G(2)) onwards until generation 9 (G(9)) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G(9) population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold.
authors.affiliation: Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, The Netherlands. djen@itz.uni-bonn.de
authors.forename: Danyel G J
authors.initials: DG
authors.lastname: Jennen
authors.forename: Addie L J
authors.initials: AL
authors.lastname: Vereijken
authors.forename: Henk
authors.initials: H
authors.lastname: Bovenhuis
authors.forename: Richard M P A
authors.initials: RM
authors.lastname: Crooijmans
authors.forename: Jan J
authors.initials: JJ
authors.lastname: van der Poel
authors.forename: Martien A M
authors.initials: MA
authors.lastname: Groenen
mesh_terms: D000818:Animals; D001823:Body Composition / Q000235:genetics*; D001947:Breeding / Q000379:methods; D002645:Chickens / Q000235:genetics*; D003433:Crosses, Genetic; D005838:Genotype; D019655:Quantitative Trait, Heritable