Chemokine signaling defines novel targets for therapeutic intervention.
Members of the human chemokine family are considered a suitable target for therapeutic intervention, as they have a fundamental role in several important human diseases. Here we outline potential new areas of intervention based on recent findings on chemokine receptor function.
Rodríguez-Frade
José Miguel
JM
Department of Immunology and Oncology, National Center of Biotechnology, CSIC, Campus Universitario de Cantoblanco, E-28049 Madrid, Spain.
Martínez-A
Carlos
C
Mellado
Mario
M
D000818:Animals; D018925:Chemokines / Q000037:antagonists & inhibitors / Q000378:metabolism*; D004194:Disease; D006801:Humans; D019707:Receptors, Chemokine / Q000037:antagonists & inhibitors / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D013812:Therapeutics / Q000379:methods*
D018925:Chemokines; D019707:Receptors, Chemokine