Prevalence of carotid artery stenosis in patients with coronary artery disease in Japanese population.
OBJECTIVE
Prevalence of carotid artery stenosis in patients with coronary artery disease (CAD) is unknown in Japanese population.


METHODS
The study populations consisted of 632 consecutive patients who underwent coronary angiography because of suspicion of CAD. All patients underwent carotid ultrasonography to screen carotid artery stenosis before coronary angiography. We defined echographic carotid stenosis as area stenosis of >50% or peak systolic velocity of >200 cm/s.


RESULTS
Echographic carotid stenosis was observed in 124 patients (19.6%). Coronary angiography revealed 433 patients had CAD. Prevalence of echographic carotid artery stenosis was 14 of 199 (7.0%), 18 of 124 (14.5%), 28 of 131 (21.4%), and 64 of 178 (36.0%) in patients with 0-, 1-, 2-, and 3-vessel CAD, respectively (P<0.0001). The prevalence rate with carotid stenosis and CAD was 25.4%. Multivariate stepwise logistic regression analysis showed that age and the extent of CAD were independently related to the presence of carotid stenosis (P=0.0002 and <0.0001, respectively).


CONCLUSIONS
Prevalence of carotid stenosis in patients with CAD is high in Japan as well as in Western countries. Screening of carotid artery stenosis is recommended especially in older patients with multivessel CAD.
Tanimoto
Shuzou
S
Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan. Shuzou_bushido@msn.com
Ikari
Yuji
Y
Tanabe
Kengo
K
Yachi
Sen
S
Nakajima
Hiroyoshi
H
Nakayama
Tomohiro
T
Hatori
Mitsuharu
M
Nakazawa
Gaku
G
Onuma
Yoshinobu
Y
Higashikuni
Yasutomi
Y
Yamamoto
Hirosada
H
Tooda
Eiichi
E
Hara
Kazuhiro
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D050197:Atherosclerosis / Q000473:pathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003251:Constriction, Pathologic; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D004452:Echocardiography; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D015999:Multivariate Analysis; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014463:Ultrasonography