title: [Discrepancies between laparoscopic and histological findings in the stage diagnosis of chronic viral hepatitis].
abstract: We studied about the discrepancies of stage diagnosis between laparoscopic and histological findings in the clinical course of chronic viral hepatitis. We noticed discrepancies in 26% of chronic hepatitis B and 18% of chronic hepatitis C. Many cases were judged more advanced by laparoscopic staging than by histological staging. The group with different stage diagnosis showed high frequency of reddish markings and patchy markings indicating severe necro-inflammatory reaction and regenerative reaction in laparoscopic findings. This suggests that existence of active inflammation might be a cause of discrepancies in stage diagnosis. The cumulative incidence of hepatocellular carcinoma was significantly higher in the cases judged more advanced by laparoscopy even in the same histological stage. This indicates that laparoscopic staging should be more reliable for predicting prognosis in each patient.
authors.affiliation: Liver disease Center, Keiyukai Yoshida Hospital.
authors.forename: Chitomi
authors.initials: C
authors.lastname: Hasebe
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Goto
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Tominaga
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Hirai
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Baba
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Chihiro
authors.initials: C
authors.lastname: Sekiya
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000473:pathology; D005260:Female; D019694:Hepatitis B, Chronic / Q000473:pathology*; D019698:Hepatitis C, Chronic / Q000473:pathology*; D006801:Humans; D010535:Laparoscopy; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged