Risk modeling to identify patients with symptomatic carotid stenosis most at risk of stroke.
We have reliable data on the degree of stenosis above which endarterectomy for symptomatic carotid stenosis is beneficial, but benefit is also influenced by other factors, particularly age, sex, the timing of surgery, plaque surface morphology and the nature of the presenting symptomatic event(s). This review will consider the selection of patients for carotid surgery based on the factors that influence the likely risk of stroke on medical treatment. In order to take into account all of the relevant factors, a risk prediction model is considered.
Rothwell
Peter M
PM
Stroke Prevention Research Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK. peter.rothwell@clneuro.ox.ac.uk
D000328:Adult; D000368:Aged; D016893:Carotid Stenosis / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D018570:Risk Assessment; D020521:Stroke / Q000453:epidemiology* / Q000517:prevention & control