title: New conjunctive reagents as cross-coupling partners en route to retinoid-like polyenes.
abstract: [structure: see text] New conjunctive reagents E-2 and Z-3 can be used, after transmetalation, in Negishi couplings with vinyl and aryl iodides. The subsequently unmasked terminal alkynes can be further manipulated to arrive at retinoid-like products.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA. lipshutz@chem.ucsb.edu
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
authors.forename: Giuliano C
authors.initials: GC
authors.lastname: Clososki
authors.forename: Will
authors.initials: W
authors.lastname: Chrisman
authors.forename: David W
authors.initials: DW
authors.lastname: Chung
authors.forename: David B
authors.initials: DB
authors.lastname: Ball
authors.forename: Jennifer
authors.initials: J
authors.lastname: Howell
mesh_terms: D000215:Acylation; D003432:Cross-Linking Reagents / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011090:Polyenes / Q000737:chemistry*; D012176:Retinoids / Q000737:chemistry*
chemical_list: D003432:Cross-Linking Reagents; D009942:Organometallic Compounds; D011090:Polyenes; D012176:Retinoids