The smallest alpha,gamma-peptide nanotubulet segments: cyclic alpha,gamma-tetrapeptide dimers.
[structure: see text] Cyclic tetrapeptides in which alpha-amino acids alternate with cis-3-aminocycloalkanecarboxylic acids dimerize by forming hydrogen bonds between their alpha-faces but not between their gamma-faces, establishing the minimal structural requirements for the novel alpha,gamma-peptide hybrids SPN.
Amorín
Manuel
M
Departamento de Química Orgánica e Unidade Asociada ó CSIC, Facultade de Química, Universidade de Santiago, 15782 Santiago de Compostela, Spain.
Brea
Roberto J
RJ
Castedo
Luis
L
Granja
Juan R
JR
D003461:Crystallography; D019281:Dimerization; D008958:Models, Molecular; D045333:Nanotubes, Peptide / Q000737:chemistry*; D010456:Peptides, Cyclic / Q000737:chemistry*; D011487:Protein Conformation
D045333:Nanotubes, Peptide; D010456:Peptides, Cyclic