title: A rapidly fatal case of T-cell lymphoma presenting as idiopathic orbital inflammation.
abstract: A 41-year-old Caucasian woman presented with a painful, red right eye with minimal systemic symptomatology, and was initially diagnosed with right idiopathic orbital inflammation. Ten days later, she developed abdominal and respiratory symptoms; this led to her demise within a further week. Post-mortem examination demonstrated widespread extranodal NK/T- cell lymphoma (nasal type), involving the right posterior orbit, lungs, uterus, left adrenal gland, pericardium and meninges. Thorough physical examination with early orbital biopsy should be considered to exclude underlying treatable pathology in managing patients with presumed idiopathic orbital inflammation.
authors.affiliation: Department of Ophthalmology, Prince of Wales Hospital, Randwick, Sydney and the University of New South Wales, Sydney, Australia.
authors.forename: Daya
authors.initials: D
authors.lastname: Papalkar
authors.forename: Shanel
authors.initials: S
authors.lastname: Sharma
authors.forename: Ian C
authors.initials: IC
authors.lastname: Francis
authors.forename: John A
authors.initials: JA
authors.lastname: Downie
authors.forename: Govindasamy
authors.initials: G
authors.lastname: Thanakrishnan
authors.forename: Louise J
authors.initials: LJ
authors.lastname: Hughes
mesh_terms: D000328:Adult; D003951:Diagnostic Errors; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007249:Inflammation; D007694:Killer Cells, Natural / Q000276:immunology; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000276:immunology; D009362:Neoplasm Metastasis; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000276:immunology; D013601:T-Lymphocytes