Postoperative radiotherapy after titanium plate mandibular reconstruction for oral cavity cancer.
OBJECTIVE
To study the impact of postoperative radiotherapy (RT) on titanium plate mandibular reconstruction.


METHODS
Between 1997 and 2002, 66 patients with oral cavity cancers had immediate titanium plate mandibular reconstruction. Thirty-four patients (51.5%) received postoperative RT and 32 patients were treated with surgery alone. Follow-up ranged from 12 to 58 months (median, 24 months).


RESULTS
Sixteen of 66 patients (24.2%) had major complications. Ten of 34 patients (29.4%) who received RT had complications compared with 6 of 32 patients (18.8%) after surgery alone (P = 0.312). The plate was removed in 11 patients (16.7%). The success rate of titanium plate reconstruction was 27 of 34 patients (79.4%) who received RT and 28 of 32 patients (87.5%) after surgery alone (P = 0.378).


CONCLUSIONS
The addition of postoperative RT did not increase the risk of complications or the likelihood of successful titanium plate reconstruction.
Wang
Zhong-He
ZH
Division of Radiation Oncology, The Shanghai Ninth People's Hospital, Shanghai Second Medical University, Shanghai, China.
Zhang
Zhi-Yuan
ZY
Mendenhall
William M
WM
D000368:Aged; D001860:Bone Plates; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000601:surgery*; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D011182:Postoperative Care; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D014025:Titanium
D014025:Titanium