Novel HLA-Cw*06 allele, Cw*0612, identified by sequence-based typing.
In this report, we describe the identification of an human leucocyte antigen-Cw*06 (HLA-Cw*06) nucleotide sequence variant, a new HLA-Cw*0612. The new allele was detected during routine HLA typing by high-resolution sequence-based typing. Allele Cw*0612 showed one nucleotide difference with Cw*0602 at codon 153 (GCG-->ACG) resulting in an amino acid change from alanine to threonine.
Hwang
S-H
SH
Department of Laboratory Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Cha
C-H
CH
Kwon
O-J
OJ
Heo
Y-S
YS
Hur
S-S
SS
Lee
M-N
MN
Oh
H-B
HB
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics* / Q000276:immunology; D001483:Base Sequence; D015236:HLA-C Antigens / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation / Q000235:genetics* / Q000276:immunology; D017434:Protein Structure, Tertiary / Q000235:genetics
D015236:HLA-C Antigens; C506275:HLA-C*06:12 antigen