title: Design, manufacture and evaluation of a NiTi stent for colon obstruction.
abstract: We have designed, manufactured and evaluated a prototype of a new stent based on the superelasticity of the NiTi alloy for colon obstruction, which is the first clinical manifestation of colorectal cancer in up to 29% of cases. The stent is auto-expandable diamond cell type, manufactured from a NiTi tube with 4.5 mm in diameter, in which longitudinal grooves were performed by cutting laser technique. The expansion process to the final shape was made by deformation in the martensite state. The stent reaches a high free expansion rate of 7, with a longitudinal variable radial strength and a bell-shaped profile in the extremes in order to avoid migration. Finite elements models were used for simulating the mechanical behaviour. The prototype was evaluated by implantation in a colon stenosis model of 6 mm in diameter performed in a porcine speciment. The stent gave a good deployment, fixation and capability to open the gap up to 15 mm in diameter.
authors.affiliation: Department of Materials Science and Technology, Centro Politécnico Superior-I3A, Zaragoza University, 50018 Zaragoza, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Domingo
authors.forename: S
authors.initials: S
authors.lastname: Puértolas
authors.forename: L
authors.initials: L
authors.lastname: Gracia-Villa
authors.forename: M
authors.initials: M
authors.lastname: Mainar
authors.forename: J
authors.initials: J
authors.lastname: Usón
authors.forename: J A
authors.initials: JA
authors.lastname: Puértolas
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000032:analysis / Q000737:chemistry*; D003108:Colonic Diseases / Q000601:surgery*; D017076:Computer-Aided Design; D019544:Equipment Failure Analysis; D007415:Intestinal Obstruction / Q000601:surgery*; D008422:Materials Testing; D008962:Models, Theoretical; D009532:Nickel / Q000032:analysis / Q000737:chemistry*; D011474:Prosthesis Design; D015607:Stents; D013552:Swine; D014025:Titanium / Q000032:analysis / Q000737:chemistry*; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; C040654:titanium nickelide; D009532:Nickel; D014025:Titanium