Cardiovascular involvement in Kawasaki disease.
We report 72 patients with Kawasaki disease seen at this Centre over 7 years. Cardiac involvement in the form of mild pancarditis was seen in 28 % patients, but disappeared subsequently. Thirteen (18.5 percent) children developed coronary artery disease, out of which 4 resolved by the end of two months and another 6 after one year; 3 patients continued to show coronary artery dilatation and aneurysm formation. Children who received IV gammaglobulin in full dose within 10 days of onset of illness, showed no evidence of coronary artery disease during follow up.
Narayanan
S Noel
SN
Department of Pediatrics and Cardiology, SAT Hospital, Medical College, Thiruvananthapuram 695 011, India. noeln@asianetindia.com
Ahamed
M Zulfikar
MZ
Safia
M
M
D017677:Age Distribution; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000453:epidemiology; D001241:Aspirin / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D005260:Female; D005334:Fever / Q000453:epidemiology; D006403:Hematologic Tests; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007194:India / Q000453:epidemiology; D007223:Infant; D008206:Lymphatic Diseases / Q000453:epidemiology; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D012189:Retrospective Studies; D017678:Sex Distribution; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous; D001241:Aspirin