Does vascular MCI progress at a different rate than does amnestic MCI?
This article reviews the evidence available from natural history studies and randomized clinical trials (RCT) concerning what is now coined as amnestic MCI and vascular MCI and will answer the question about the similarity and difference of their progression toward dementia. The issues to be resolved prior to the use of a survival design for conversion from vascular MCI to dementia will be discussed.
Gauthier
Serge
S
McGill Centre for Studies in Aging, McGill University, Montreal, Canada. serge.gauthier@mcgill.ca
Rockwood
Kenneth
K
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000503:physiopathology; D000647:Amnesia / Q000175:diagnosis* / Q000209:etiology*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D015140:Dementia, Vascular / Q000150:complications* / Q000503:physiopathology*; D018450:Disease Progression; D006801:Humans; D016032:Randomized Controlled Trials as Topic