Oestrogen and progesterone receptors in primary mucinous carcinoma of skin.
A 74-year-old man presented with a recurrent indolent growth in the left axilla. Fine-needle aspiration cytology and histopathological examination showed a picture of mucinous adenocarcinoma. Clinical examination and systemic investigations failed to detect any primary lesion elsewhere and hence, a diagnosis of primary mucinous carcinoma of the skin was made. This tumour shows histological resemblance to mucinous carcinoma of breast. We also demonstrated expression of oestrogen and progesterone receptors in this tumour. This observation suggests that there is a potential of using antioestrogenic therapy in patients with primary cutaneous mucinous carcinoma, especially because of its high rate of local recurrence.
Kwatra
Kanwardeep S
KS
Mohan Dai Oswal Cancer Treatment and Research Foundation, Ludhiana, Punjab, India. kanwardeepkwatra@rediffmail.com
Prabhakar
Baldev R
BR
Jain
Satish
S
D002288:Adenocarcinoma, Mucinous / Q000378:metabolism* / Q000473:pathology*; D000368:Aged; D001365:Axilla / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone