Iatrogenic calcinosis cutis following nadroparin injection.
Accumulation of calcium in the skin is usually classified as a group of disorders referred to as calcinosis cutis. We report the case of a patient who developed iatrogenic calcinosis at the site of subcutaneous administration of low-molecular-weight heparins (LMWH) as nadroparin. This is usually used for the prevention of deep venous thrombosis, especially following renal transplantation. The role of calcium content in nadroparin is discussed.
Giorgini
Simonetta
S
Department of Dermatological Sciences, University of Florence, Florence, Italy. Simygiorgini@libero.it
Martinelli
Canio
C
Massi
Daniela
D
Lumini
Annalisa
A
Mannucci
Marco
M
Giglioli
Leonetto
L
D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D002114:Calcinosis / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007049:Iatrogenic Disease; D007279:Injections, Subcutaneous / Q000009:adverse effects; D008297:Male; D017762:Nadroparin / Q000009:adverse effects* / Q000627:therapeutic use; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology*; D020246:Venous Thrombosis / Q000517:prevention & control
D000925:Anticoagulants; D017762:Nadroparin