Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis.
This report updates U.S. Public Health Service recommendations for the management of health-care personnel (HCP) who have occupational exposure to blood and other body fluids that might contain human immunodeficiency virus (HIV). Although the principles of exposure management remain unchanged, recommended HIV postexposure prophylaxis (PEP) regimens have been changed. This report emphasizes adherence to HIV PEP when it is indicated for an exposure, expert consultation in management of exposures, follow-up of exposed workers to improve adherence to PEP, and monitoring for adverse events, including seroconversion. To ensure timely postexposure management and administration of HIV PEP, clinicians should consider occupational exposures as urgent medical concerns.
Panlilio
Adelisa L
AL
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, CDC, 1600 Clifton Rd., NE, MS E-68, Atlanta, Georgia 30333, USA. alp4@cdc.gov
Cardo
Denise M
DM
Grohskopf
Lisa A
LA
Heneine
Walid
W
Ross
Clara Sue
CS
D019380:Anti-HIV Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission*; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D016273:Occupational Exposure
D019380:Anti-HIV Agents