title: Linezolid treatment of ventriculoperitoneal shunt infection without implant removal.
abstract: Ventriculoperitoneal shunt infection is a serious clinical problem for which implant removal is considered the treatment of choice. However, surgery is sometimes associated with considerable risks that may outweigh the benefits. Presented here is a case of ventriculoperitoneal shunt infection treated successfully with linezolid without implant removal. This case shows linezolid could be a therapeutic alternative when surgery is contraindicated.
authors.affiliation: Department of Infectious Diseases, Hospital Clínic, Villarroel 170, Barcelona, 08036, Spain. castroreb@yahoo.es
authors.forename: P
authors.initials: P
authors.lastname: Castro
authors.forename: A
authors.initials: A
authors.lastname: Soriano
authors.forename: C
authors.initials: C
authors.lastname: Escrich
authors.forename: G
authors.initials: G
authors.lastname: Villalba
authors.forename: M
authors.initials: M
authors.lastname: Sarasa
authors.forename: J
authors.initials: J
authors.lastname: Mensa
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D020878:Device Removal; D006801:Humans; D000069349:Linezolid; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D023303:Oxazolidinones / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology*; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000302:isolation & purification; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D000069349:Linezolid