Surrogate nutrition markers, malnutrition, and adequacy of nutrition support.
Surrogate nutrition markers are used to assess adequacy of nourishment and to define malnutrition despite evidence that fails to link nourishment, surrogate markers, and outcomes. Markers such as serum levels of albumin, prealbumin, transferrin, and IGF-1 and delayed hypersensitivity and total lymphocyte count may be valid to help stratify risk. However, it is not appropriate to consider these as markers of adequacy of nourishment in the sick patient.
Seres
David S
DS
Department of Medicine, Beth Israel Medical Center and Albert Einstein College of Medicine, New York, New York, USA. dseres@chpnet.org
D015415:Biomarkers / Q000032:analysis*; D019317:Evidence-Based Medicine; D006801:Humans; D044342:Malnutrition / Q000175:diagnosis* / Q000628:therapy*; D018529:Nutritional Support / Q000592:standards*; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
D015415:Biomarkers