Statins: the case for higher, individualized starting doses.
If patients with hypercholesterolemia were started on higher doses of statins tailored to their lipid levels and risk, more of them would achieve their low-density lipoprotein cholesterol (LDL-C) goals, possibly leading to fewer cardiovascular events and deaths.
Jones
Peter H
PH
Lipid Metabolism and Atherosclerosis Clinic, Section of Atherosclerosis and Lipid Research, Baylor College of Medicine, Houston, TX, USA. jones@bcm.tmc.edu
D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D018570:Risk Assessment
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors