DAT1 VNTR allele frequencies in the Omani population.
To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The frequency of the observed genotypes was not significantly different from the expected Hardy-Weinberg distribution. We compared the Omani DAT1 alleles with similar data from other populations.
Simsek
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Sultan Qaboos University, College of Medicine, Department of Biochemistry, P.O. Box 35, Al Khod, Postal Code 123 Muscat, Sultanate of Oman.
Lawatia
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K
Al-Adawi
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Al-Sharbati
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D050483:Dopamine Plasma Membrane Transport Proteins / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics*; D009850:Oman; D011110:Polymorphism, Genetic / Q000235:genetics*
D050483:Dopamine Plasma Membrane Transport Proteins; C493214:SLC6A3 protein, human