title: [Study on the expression of human acute myeloid leukemia retrovirus gene].
abstract: OBJECTIVE
  To explore the potentiality of retroviral etiology in human acute myeloid leukemia (AML).
  
  
  METHODS
  The expression of retrovirus clone 6 # 11 in leukemic cells from 19 AML patients and peripheral blood mononuclear cells (PBMNCs) from 20 controls was studied by Northern blot and reverse transcriptase polymerase chain reaction (RT-PCR).
  
  
  RESULTS
  Northern blot revealed the positive bands of 9.4 kb and 4.5 kb in 18 of 19 AML patients, and RT-PCR a 790 bp product in 11 of 14 AML patients.
  
  
  CONCLUSIONS
  There was a specific expression of acute myeloid leukemia associated retrovirus in AML patients.
authors.affiliation: Department of Hematology, The Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China.
authors.forename: X
authors.initials: X
authors.lastname: Xu
authors.forename: R
authors.initials: R
authors.lastname: Xu
authors.forename: S
authors.initials: S
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D015152:Blotting, Northern; D005260:Female; D006678:HIV / Q000235:genetics; D015368:Human T-lymphotropic virus 1 / Q000235:genetics; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology / Q000821:virology*; D008297:Male; D008875:Middle Aged; D012190:Retroviridae / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction