title: [Calcium antagonist and diurnal blood pressure variation].
abstract: Many evidences have been established about reduction of cardiovascular event of long-acting calcium antagonists. It has been reported that long-acting calcium antagonists reduce cardiovascular risk more than other drugs, and calcium antagonists are important in Japan, where stroke is very popular and calcium antagonists are widely used. Calcium antagonists have not only strength and sharpness of reduction blood pressure (BP), but also improve morning hypertension and abnormal variation of BP through appropriate reduction of BP. Calcium antagonists might be used after due consideration home and ambulatory BP in addition to clinic BP.
authors.affiliation: Ogano Central Hospital.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kabutoya
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Kario
mesh_terms: D000959:Antihypertensive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use; D002940:Circadian Rhythm / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy
chemical_list: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers