title: Two-stage enzyme mediated drug release from LMWG hydrogels.
abstract: An enzymatically cleavable low molecular weight gelator-(model) drug conjugate system can be employed to effect a two-step enzyme mediated drug release, demonstrating the potential of LMWG systems for the development of drug delivery devices.
authors.affiliation: Biomade Technology Foundation, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. van.bommel@biomade.nl
authors.forename: Kjeld J C
authors.initials: KJ
authors.lastname: van Bommel
authors.forename: Marc C A
authors.initials: MC
authors.lastname: Stuart
authors.forename: Ben L
authors.initials: BL
authors.lastname: Feringa
authors.forename: Jan
authors.initials: J
authors.lastname: van Esch
mesh_terms: D002918:Chymotrypsin; D016503:Drug Delivery Systems; D020100:Hydrogels; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008970:Molecular Weight
chemical_list: D020100:Hydrogels; D002918:Chymotrypsin; C117608:alpha-chymotrypsin