title: Topography-guided custom retreatments in 27 symptomatic eyes.
abstract: OBJECTIVE
  To evaluate the use of topography-guided ablations for refractive irregularities induced by previous surgery.
  
  
  METHODS
  This prospective, non-comparative trial comprised 27 symptomatic eyes with a history of LASIK for myopia that underwent topography-guided treatment with the ALLEGRETTO WAVE system. Pre- and postoperative refraction, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), corneal asphericity (Q value), low contrast sensitivity, and patient's subjective assessment of improvement were measured.
  
  
  RESULTS
  Preoperative data were sphere -0.84 +/- 1.37 diopters (D), cylinder -1.55 +/- 0.78 D, UCVA 20/49 +/- 0.22, BSCVA 20/32 +/- 0.15, and Q value 1.46 +/- 0.79. Postoperative data at mean 6-month follow-up were: sphere -0.61 +/- 0.81 D, cylinder -0.53 +/- 0.58 D, UCVA 20/25 +/- 0.21 (P < .01), BSCVA 20/21 +/- 0.14 (P < .001), and Q value 1.07 +/- 0.89. Contrast sensitivity scores improved by 70%. No loss of BSCVA occurred in any patient.
  
  
  CONCLUSIONS
  Topography-guided treatments may be effective in correcting the quality of vision. It should be viewed as a possible two-step procedure due to spherical adjustment that may change refraction unpredictably.
authors.affiliation: LaserVision.gr Eye Institute, Athens, Greece. laservision@internet.gr
authors.forename: A John
authors.initials: AJ
authors.lastname: Kanellopoulos
mesh_terms: D015350:Contrast Sensitivity; D003319:Corneal Stroma / Q000601:surgery*; D019781:Corneal Topography / Q000379:methods*; D006801:Humans; D006956:Hyperopia / Q000601:surgery*; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D009216:Myopia / Q000601:surgery*; D011446:Prospective Studies; D012029:Refraction, Ocular; D012086:Reoperation; D013524:Surgical Flaps; D014792:Visual Acuity