title: Ring-expanding reaction of cyclopropyl amides with triphenylphosphine and carbon tetrahalide.
abstract: We succeeded in activating cyclopropyl amides (monoactivated cyclopropane) through the corresponding imidoyl halides prepared in situ in the presence of 2 equiv of PPh3 and 1 equiv of CX4, and the ring-expanding products (N-substituted pyrrolidin-2-ones) were obtained in good yields. The reaction mechanism was investigated on the basis of oxygen-18 tracer experiment.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Yang
authors.forename: Min
authors.initials: M
authors.lastname: Shi