Immunogenicity of an intranasally administered modified live canine parvovirus type 2b vaccine in pups with maternally derived antibodies.
The ability of a modified live canine parvovirus type 2b vaccine to elicit active immunization in pups with maternally derived antibodies (MDA) by intranasal administration was evaluated. The vaccine induced seroconversion in 100% of pups with MDA titers of < or = 80 and in 51.6% of pups with titers between 160 and 320.
Martella
Vito
V
Department of Animal Health and Well-Being, Faculty of Veterinary Medicine, University of Bari, S.p. per Casamassima km 3, 70010 Valenzano, Bari, Italy. v.martella@veterinaria.uniba.it
Cavalli
Alessandra
A
Decaro
Nicola
N
Elia
Gabriella
G
Desario
Costantina
C
Campolo
Marco
M
Bozzo
Giancarlo
G
Tarsitano
Elvira
E
Buonavoglia
Canio
C
D000281:Administration, Intranasal; D000818:Animals; D000914:Antibodies, Viral / Q000627:therapeutic use*; D004285:Dogs; D007114:Immunization; D010322:Parvoviridae Infections / Q000517:prevention & control / Q000662:veterinary; D017993:Parvovirus, Canine / Q000276:immunology*; D014765:Viral Vaccines
D000914:Antibodies, Viral; D014765:Viral Vaccines