title: PROPELLER EPI: an MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions.
abstract: A technique suitable for diffusion tensor imaging (DTI) at high field strengths is presented in this work. The method is based on a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) k-space trajectory using EPI as the signal readout module, and hence is dubbed PROPELLER EPI. The implementation of PROPELLER EPI included a series of correction schemes to reduce possible errors associated with the intrinsically higher sensitivity of EPI to off-resonance effects. Experimental results on a 3.0 Tesla MR system showed that the PROPELLER EPI images exhibit substantially reduced geometric distortions compared with single-shot EPI, at a much lower RF specific absorption rate (SAR) than the original version of the PROPELLER fast spin-echo (FSE) technique. For DTI, the self-navigated phase-correction capability of the PROPELLER EPI sequence was shown to be effective for in vivo imaging. A higher signal-to-noise ratio (SNR) compared to single-shot EPI at an identical total scan time was achieved, which is advantageous for routine DTI applications in clinical practice.
authors.affiliation: Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, R.O.C.
authors.forename: Fu-Nien
authors.initials: FN
authors.lastname: Wang
authors.forename: Teng-Yi
authors.initials: TY
authors.lastname: Huang
authors.forename: Fa-Hsuan
authors.initials: FH
authors.lastname: Lin
authors.forename: Tzu-Chao
authors.initials: TC
authors.lastname: Chuang
authors.forename: Nan-Kuei
authors.initials: NK
authors.lastname: Chen
authors.forename: Hsiao-Wen
authors.initials: HW
authors.lastname: Chung
authors.forename: Cheng-Yu
authors.initials: CY
authors.lastname: Chen
authors.forename: Kenneth K
authors.initials: KK
authors.lastname: Kwong
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000166:cytology*; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity