[Effect of static magnetic field on bone morphogenetic protein-2 in periodontal membrane of experimental periodontitis rat].
OBJECTIVE
To evaluate the effect of static magnetic field on expression of bone morphogenetic protein-2(BMP-2) in the periodontal membrane of experimental periodontitis rat.


METHODS
Experimental periodontitis of rat was formed by ligaturing the neck of rat teeth and feeding sugar of high concentration. The magnet which the intensity of magnetic field was 0.12 tesla was put into their cheeks. The rats were sacrificed at 2nd day, 4th day and 7th day, respectively. Immuno-histochemical techniques were used to evaluate the change of BMP-2 expression.


RESULTS
BMP-2 was mainly found in the plasma of fibroblast, osteoblast, cementocyte and odontoblast separately. There was not clearly difference between the periodontitis group and the normal group, but BMP-2 in the experimental group treated with static magnetic field was higher than the two groups.


CONCLUSIONS
Static magnetic field plays an important role in repairing and remodeling of periodontitis.
Qiu
Li-Hong
LH
Dept. of Oral Medicine, College of Stomatology, China Medical University, Shenyang 110002, China.
Qin
Ke
K
Zhong
Ming
M
Wang
Zhao-Yuan
ZY
D000818:Animals; D055396:Bone Morphogenetic Protein 2; D060526:Magnetic Fields; D010006:Osteoblasts; D010513:Periodontal Ligament; D010518:Periodontitis; D051381:Rats
D055396:Bone Morphogenetic Protein 2