title: Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays.
abstract: We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).
authors.affiliation: Division of Retrovirology, WalterReed Army Institute of Research, Rockville, MD 20850, USA.
authors.forename: Darrell E
authors.initials: DE
authors.lastname: Singer
authors.forename: Noah
authors.initials: N
authors.lastname: Kiwanuka
authors.forename: David
authors.initials: D
authors.lastname: Serwadda
authors.forename: Fred
authors.initials: F
authors.lastname: Nalugoda
authors.forename: Linda
authors.initials: L
authors.lastname: Hird
authors.forename: Jamie
authors.initials: J
authors.lastname: Bulken-Hoover
authors.forename: Godfrey
authors.initials: G
authors.lastname: Kigozi
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Malia
authors.forename: Eva K
authors.initials: EK
authors.lastname: Calero
authors.forename: Warren
authors.initials: W
authors.lastname: Sateren
authors.forename: Merlin L
authors.initials: ML
authors.lastname: Robb
authors.forename: Fred
authors.initials: F
authors.lastname: Wabwire-Mangen
authors.forename: Maria
authors.initials: M
authors.lastname: Wawer
authors.forename: Ronald H
authors.initials: RH
authors.lastname: Gray
authors.forename: Nelson
authors.initials: N
authors.lastname: Sewankambo
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Birx
authors.forename: Nelson L
authors.initials: NL
authors.lastname: Michael
mesh_terms: D015492:AIDS Serodiagnosis; D000465:Algorithms; D016001:Confidence Intervals; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D012680:Sensitivity and Specificity; D044967:Serum; D013048:Specimen Handling / Q000379:methods*; D013997:Time Factors; D014454:Uganda
chemical_list: D015483:HIV Antibodies