Ethnic differential item functioning in the assessment of quality of life in cancer patients.
BACKGROUND
Past research has shown that Filipino cancer patients report lower levels of quality of life (QoL) than other ethnic groups. One possible explanation for this is that Filipinos do not define QoL in the same manner as others, resulting in bias in their assessments. Hence, Filipinos would not necessarily have lower QoL.


METHODS
Item response theory methods were used to assess differential item functioning (DIF) in the quality of life (measured by the EORTC QLQ-C30) of cancer patients across four ethnic groups (Caucasian, Filipino, Hawaiian, and Japanese). The sample consisted of 359 cancer patients.


RESULTS
Results showed the presence of DIF on several items, indicating ethnic differences in the assessment of quality of life. Relative to the Caucasian and Japanese groups, items related to physical functioning, cognitive functioning, social functioning, nausea and vomiting, and financial difficulties exhibited DIF for Filipinos. On these items Filipinos exhibited either higher or lower QoL scores, even though their overall QoL was the same.


CONCLUSIONS
This evidence may explain why Filipinos have previously been found to have lower overall QoL. Although Filipinos score lower on QoL than other groups, this may not reflect lower QoL, but rather differences in how QoL is defined. The presence of DIF did not appear, however, to alter the psychometric properties of the QLQ-C30.
Pagano
Ian S
IS
Cancer Research Center of Hawaii, Honolulu, HI 96813, USA. ian@crch.hawaii.edu
Gotay
Carolyn C
CC
D000368:Aged; D001213:Asian / Q000523:psychology*; D001294:Attitude to Health / Q000208:ethnology*; D003466:Cultural Characteristics; D005260:Female; D006254:Hawaii; D006801:Humans; D007564:Japan / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000208:ethnology* / Q000523:psychology; D010679:Philippines / Q000208:ethnology; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life / Q000523:psychology*; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D044465:White People / Q000523:psychology