title: Practical and efficient Suzuki-Miyaura cross-coupling of 2-iodocycloenones with arylboronic acids catalyzed by recyclable Pd(0)/C.
abstract: The first Suzuki-Miyaura cross-coupling of 2-iodocycloenones with arylboronic acids catalyzed by 10% Pd(0)/C is described as an interesting alternative to classical homogeneous conditions. Most of the substrate reacted under mild condition at 25 degrees C under air in aqueous DME. The conditions described tolerate a wide range of iodoenones and boronic acids. Notably, the procedure features inexpensive reagents and solvents with low toxicity rendering the method environmentally benign. Additionally 10% Pd(0)/C could be recovered and efficiently reused at least five times without significant alteration of the yields of the cross-coupled product.
authors.affiliation: Université Bordeaux-I, Laboratoire de Chimie Organique et Organométallique, 351 Cours de la Libération, 33405 Talence Cedex, France. fx.felpin@lcoo.u-bordeaux1.fr
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Felpin