[Gastric cytomedines effects on immune response in acute immobilization stress in rats].
Effects of gastric cytomedines on repair and immune response were studied in 137 white non-inbred rats. Erosions of gastric mucosa were induced by acute immobilization stress. A decrease in antibody production, titers of hemagglutinins and hemolysins was found on day 2 after stress. Gastric cytomedines in a dose 0.15 mg/kg intramuscularly stimulate immune response (increased production of antibodies, antibody dependent cellular cytotoxicity index, titers of hemagglutinins and hemolysins), fast erosions epithelization and have a protective action.
Shcherbak
V A
VA
Malezhik
L P
LP
Aksenova
T A
TA
Pateiuk
A V
AV
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D000906:Antibodies / Q000097:blood; D005753:Gastric Mucosa / Q000187:drug effects; D006388:Hemagglutinins / Q000097:blood; D006460:Hemolysin Proteins / Q000097:blood; D007107:Immune System / Q000187:drug effects*; D010437:Peptic Ulcer / Q000276:immunology*; D010455:Peptides / Q000494:pharmacology*; D051381:Rats; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000276:immunology*
D000897:Anti-Ulcer Agents; D000906:Antibodies; D006388:Hemagglutinins; D006460:Hemolysin Proteins; D010455:Peptides; C053892:cytomedins