Implicit solvent simulation models for biomembranes.
Fully atomic simulation strategies are infeasible for the study of many processes of interest to membrane biology, biophysics and biochemistry. We review various coarse-grained simulation methodologies with special emphasis on methods and models that do not require the explicit simulation of water. Examples from our own research demonstrate that such models have potential for simulating a variety of biologically relevant phenomena at the membrane surface.
Brannigan
Grace
G
Department of Physics and Astronomy, University of California, Santa Barbara, CA 93106-9530, USA.
Lin
Lawrence C-L
LC
Brown
Frank L H
FL
D055592:Biophysical Phenomena; D001703:Biophysics; D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism; D003198:Computer Simulation; D008051:Lipid Bilayers / Q000737:chemistry*; D008954:Models, Biological; D012997:Solvents / Q000737:chemistry; D013499:Surface Properties
D008051:Lipid Bilayers; D012997:Solvents