title: Percutaneous cervical oesophageal cannulation in the dog for the performance of prolonged oesophageal pH and manometric studies.
abstract: Traditional methods for obtaining oesophageal access in experimental animals are unsuitable for prolonged (24 h) oesophageal pH evaluation, a procedure that is commonly employed in the assessment of human patients suspected of having gastroesophageal reflux disease. In the present study, we describe a six-year experience with a technique of percutaneous oesophagostomy for the performance of serial 24 h oesophageal pH and manometric studies involving 62 dogs and a total of 208 oesophageal cannula placement procedures. The results indicate a considerable improvement over previously described techniques with respect to simplicity of surgical technique, associated morbidity, oesophagostomy management, animal conditioning, and avoidance of chemical and excessive physical restraints in animals undergoing oesophageal pH and manometric evaluation.
authors.affiliation: Endosurgical Research Group, Department of Surgery, Duke University Medical Center, Box 3247 Medical Center, Durham, NC 27710, USA. eclary@cvssweb.com
authors.forename: E M
authors.initials: EM
authors.lastname: Clary
authors.forename: R J
authors.initials: RJ
authors.lastname: Manson
authors.forename: S
authors.initials: S
authors.lastname: Lagoo
authors.forename: T N
authors.initials: TN
authors.lastname: Pappas
authors.forename: S
authors.initials: S
authors.lastname: Eubanks
mesh_terms: D000818:Animals; D002404:Catheterization / Q000379:methods / Q000662:veterinary*; D004285:Dogs / Q000601:surgery*; D004947:Esophagus / Q000601:surgery*; D006863:Hydrogen-Ion Concentration; D008365:Manometry