[Progress in research on anthocyanidin components in Chinese traditional medicine against neoplasm].
Anthocyanidin is a type of the plant pigments distributed very extensively, in traditional Chinese herbal products as well. In this review was introduced the recently progress in the anti-cancer trials of anthocyanidins, including the anti-oxidation, the prevention of DNA strand scission, stimulation of cell differentiation, induction of cell apoptosis, interference of regulation of cell proliferation, anti-angiogenic property etc, and the research of anti-cancer mechanisms of anthocyanidin and its structure-activity relationship, pointed the foreground of research and development of anti-cancer medicine.
Lin
Xiao-Xia
XX
Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China. linxx915@163.com
Zhu
Shou-Min
SM
D000818:Animals; D000872:Anthocyanins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D053938:DNA Fragmentation / Q000187:drug effects; D006801:Humans; D009369:Neoplasms / Q000473:pathology*; D009389:Neovascularization, Pathologic; D010946:Plants, Medicinal / Q000737:chemistry; D013329:Structure-Activity Relationship
D000872:Anthocyanins; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants