title: Treatment options in early stages of Hodgkin's Lymphoma, high cure rate with lower short and long-term toxicity.
abstract: The definition of early stages in HL varied among cooperative groups and clinical trials. Most of them considered early stages; stage I, II, and IIIA without bulky disease. Bulky disease has been defined at the Costwolds Meeting as those tumors with more than 10 cm or a mediastinal involvement of more than one-third of the chest wall diameter. Other factors that have been considered unfavorable within the early stages are old age, high ESR, mixed cellularity or lymphocyte depleted histology, B symptoms or multiple sites of disease.
authors.affiliation: FUNDALEU, Centro de Internación e Investigación Clínica Angélica Ocampo, Buenos Aires, Argentina.
authors.forename: Santiago
authors.initials: S
authors.lastname: Pavlovsky
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D016609:Neoplasms, Second Primary / Q000139:chemically induced