title: In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes.
abstract: The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the interpulse period. Charge-injection limits were compared over a bias range of 0.1-0.7 V (versus Ag/AgCl) and pulse frequencies of 20, 50, and 100 Hz. The AIROF was capable of injecting between 4 and 10 times the charge of the PtIr electrode, with a maximum value of 3.9 mC/cm2 obtained at a 0.7 V bias and 20 Hz frequency.
authors.affiliation: EIC Laboratories Inc, 111 Downey St, Norwood, MA 02062, USA. scogan@eiclabs.com
authors.forename: Stuart F
authors.initials: SF
authors.lastname: Cogan
authors.forename: Philip R
authors.initials: PR
authors.lastname: Troyk
authors.forename: Julia
authors.initials: J
authors.lastname: Ehrlich
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Plante
mesh_terms: D017097:Electric Impedance; D004558:Electric Stimulation / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007495:Iridium / Q000032:analysis / Q000737:chemistry*; D008839:Microelectrodes; D017671:Platinum Compounds / Q000032:analysis / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D017671:Platinum Compounds; C044458:iridium oxide; D007495:Iridium