title: Influence of prenatal noise and music on the spatial memory and neurogenesis in the hippocampus of developing rats.
abstract: During the prenatal period, the development of individual is influenced by the environmental factors. In the present study, the influence of prenatal noise and music on the spatial memory and neurogenesis in the hippocampus of developing rats was investigated. The exposure to the noise during pregnancy caused growth retardation, decreased neurogenesis in the hippocampus, and impaired spatial learning ability in pups. The exposure to music during pregnancy, on the other hand, caused increased neurogenesis in the hippocampus and enhanced spatial learning ability in pups. The present study has shown the importance of the prenatal environmental conditions for the cognition and brain development.
authors.affiliation: Department of Physiology, College of Medicine, Kyung Hee University, #1 Hoigi-dong, Dongdaemoon-gu, Seoul 130-701, South Korea.
authors.forename: Hong
authors.initials: H
authors.lastname: Kim
authors.forename: Myoung-Hwa
authors.initials: MH
authors.lastname: Lee
authors.forename: Hyun-Kyung
authors.initials: HK
authors.lastname: Chang
authors.forename: Taeck-Hyun
authors.initials: TH
authors.lastname: Lee
authors.forename: Hee-Hyuk
authors.initials: HH
authors.lastname: Lee
authors.forename: Min-Chul
authors.initials: MC
authors.lastname: Shin
authors.forename: Mal-Soon
authors.initials: MS
authors.lastname: Shin
authors.forename: Ran
authors.initials: R
authors.lastname: Won
authors.forename: Hye-Sook
authors.initials: HS
authors.lastname: Shin
authors.forename: Chang-Ju
authors.initials: CJ
authors.lastname: Kim
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal; D001835:Body Weight / Q000502:physiology; D001973:Bromodeoxyuridine / Q000378:metabolism; D002452:Cell Count / Q000379:methods; D005260:Female; D006624:Hippocampus / Q000166:cytology / Q000254:growth & development / Q000502:physiology*; D008297:Male; D018782:Maze Learning / Q000502:physiology; D008568:Memory / Q000502:physiology*; D009146:Music; D009474:Neurons / Q000502:physiology*; D009622:Noise / Q000009:adverse effects*; D038081:Organogenesis; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D013037:Spatial Behavior / Q000502:physiology*; D013997:Time Factors
chemical_list: D001973:Bromodeoxyuridine