[The relationship between adenoids hypertrophy and secretory otitis media].
OBJECTIVE
To investigate the relationship between immune status of adenoids and secretory otitis media (SOM).


METHODS
All the 76 cases of SOM were divided into 2 groups: recurrent group (46 cases) and control group (30 cases whose occurrence was less than 3 times). The manifestation of CD45RO, CD20, PCNA and BCL-2 in adenoids was detected with ultrasensitive (TM)S-P immunohistology.


RESULTS
The expression of CD44Ro, CD20, PCNA and BCL-2 in recurrent group was significantly higher than that in control group (P < 0.05 or P < 0.01).


CONCLUSIONS
In adenoid tissues of recurrent SOM patients, the activities of lymphocytes and cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. Therefore, adenoidectomy for SOM patients should be carried out as early as possible.
Yin
Guiru
G
Department of Otolaryngology, the Affiliated Hospital of Chengde Medical College, Chengde, 067000, China. JTJ9995@sina.com
Yue
Zhuoli
Z
Hu
Jiangong
J
Zhao
Xiaoming
X
D000234:Adenoids / Q000276:immunology* / Q000473:pathology; D018951:Antigens, CD20 / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D017493:Leukocyte Common Antigens / Q000032:analysis; D008297:Male; D010034:Otitis Media with Effusion / Q000276:immunology* / Q000473:pathology; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D012008:Recurrence
D018951:Antigens, CD20; D018809:Proliferating Cell Nuclear Antigen; D019253:Proto-Oncogene Proteins c-bcl-2; D017493:Leukocyte Common Antigens