Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1-year prospective study.
To determine whether children have persistent abnormalities in cellular and humoral immunity development after acute Mycoplasma pneumoniae infection, serum immunoglobulin G (IgG), IgA, IgM, and IgE levels and lymphocyte phenotypes were determined. There were no changes in the levels of IgG, IgM, IgA, or CD4+ or CD19+ lymphocytes that were measured in M. pneumoniae-positive patients after 3 months or after 12 months, but there were increases in these in M. pneumoniae-negative patients. Serum IgE increased in M. pneumoniae-positive patients. We have shown alterations in immunity development after M. pneumoniae infection.
Stelmach
Iwona
I
M. Curie Hospital, Department of Pediatrics and Allergy, 35 Parzeczewska Str., 95-100 Zgierz, Poland. interna@wss.zgierz.pl
Podsiadłowicz-Borzecka
Malgorzata
M
Grzelewski
Tomasz
T
Majak
Pawel
P
Stelmach
Wlodzimierz
W
Jerzyńska
Joanna
J
Popławska
Marta
M
Dziadek
Jaroslaw
J
D000917:Antibody Formation; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007107:Immune System / Q000382:microbiology; D007111:Immunity, Cellular; D007132:Immunoglobulin Isotypes / Q000097:blood; D016130:Immunophenotyping; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D011019:Pneumonia, Mycoplasma / Q000276:immunology*; D011446:Prospective Studies; D013997:Time Factors
D007132:Immunoglobulin Isotypes