title: [Complications in a patient with liver cirrhosis and HCV coinfection during treatment with peginterferon and ribavirin].
abstract: Authors present a case of 15-years old girl with liver cirrhosis due to biliary atresia with HCV coinfection with portal hypertension after several episodes of variceal bleeding treated primarily with sclerotherapy and later with transjugular intrahepatic porto-systemic stent shunt. In a patient during the combined peginterferon alfa-2b and ribavirin treatment a decompensation of liver occurred with necessity for liver transplantation.
authors.affiliation: Klinika Gastrologii, Hepatologii i Immunologii IP-CZD. liver@czd.waw.pl
authors.forename: Joanna
authors.initials: J
authors.lastname: Pawłowska
authors.forename: Etienne
authors.initials: E
authors.lastname: Sokal
authors.forename: Irena
authors.initials: I
authors.lastname: Jankowska
authors.forename: Mikołaj
authors.initials: M
authors.lastname: Teisseyre
authors.forename: Maria
authors.initials: M
authors.lastname: Rokitka
authors.forename: Jerzy
authors.initials: J
authors.lastname: Socha
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000009:adverse effects*; D001656:Biliary Atresia / Q000150:complications; D002648:Child; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects*; D008103:Liver Cirrhosis / Q000150:complications* / Q000188:drug therapy* / Q000209:etiology; D017093:Liver Failure / Q000209:etiology* / Q000601:surgery; D016031:Liver Transplantation; D011092:Polyethylene Glycols; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011994:Recombinant Proteins; D012254:Ribavirin / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C417083:peginterferon alfa-2b