[Effects of the volatile oil of Centipeda minima on acute pleural effusion in rats induced by an intrapleural injection of car].
OBJECTIVE
To study the anti-inflammation effect of volatile oil of Centipeda minima and the mechanism of action.


METHODS
The animal model was induced by the Car injection into intrapleural of rats, to observe the effect of VOCM on acute inflammation.


RESULTS
VOCM was able to inhibit the increase of NO, CRP and proinflammatory cytokines such as TNFalpha in the acute inflammation of the rat body.


CONCLUSIONS
VOCM has a protective effect on acute pleural effusion in rats induced by an intrapleural injection of Car.
Qin
Ren-An
RA
Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China. gzqra@etang.com
Mei
Xuan
X
Wan
Lei
L
Shi
Jing-Li
JL
Shen
Ying-Jun
YJ
D000818:Animals; D019659:Asteraceae / Q000737:chemistry; D002097:C-Reactive Protein / Q000378:metabolism; D002351:Carrageenan; D015232:Dinoprostone / Q000378:metabolism; D016209:Interleukin-8 / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D010996:Pleural Effusion / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D016209:Interleukin-8; D009822:Oils, Volatile; D014409:Tumor Necrosis Factor-alpha; D009569:Nitric Oxide; D002351:Carrageenan; D002097:C-Reactive Protein; D015232:Dinoprostone