Regular abdominal pain and fever in each menstruation onset: an unusual menses-associated familial Mediterrenean fever attacks and a favor result on colchicine treatment.
We present a 38-year-old woman suffering from regular abdominal pain and fever only in each menstruation onset for 7 years. The clinical symptoms, along with inflammatory findings during painful attacks, the beneficial effect of colchicine and genetic mutation (M694 V and M680I) supported the diagnosis of familial Mediterranean fever (FMF). A literature review indicated that FMF attacks occurring only during menstruation are rarely seen. This clinical picture may be confused with gynecological disorders especially in the people of Mediterranean origin.
Düzgün
Nurşen
N
Department of Clinical Immunology and Rheumatology, Ankara University, School of Medicine, Ankara, Turkey. duzgun@medicine.ankara.edu.tr
Ateş
Aşkin
A
Tuna
Serpil
S
D015746:Abdominal Pain / Q000209:etiology*; D000328:Adult; D003078:Colchicine / Q000627:therapeutic use*; D010505:Familial Mediterranean Fever / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D005260:Female; D005334:Fever / Q000209:etiology*; D005500:Follow-Up Studies; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D008599:Menstruation Disturbances / Q000150:complications / Q000235:genetics*; D013997:Time Factors; D016896:Treatment Outcome
D006074:Gout Suppressants; D003078:Colchicine