title: Clinical correlation between motor evoked potentials and gait recovery in poststroke patients.
abstract: OBJECTIVE
  To evaluate, in patients with a stroke in the area of the middle cerebral artery, whether transcranial magnetic stimulation values from the affected lower limb correlated with the degree of gait recovery.
  
  
  METHODS
  The prognostic evaluation in subjects with complete lower-limb palsy, inability to walk, and dependence in the activities of daily living, 1 month after vascular injury.
  
  
  METHODS
  University-affiliated rehabilitation hospital.
  
  
  METHODS
  Twenty consecutive patients (12 women, 8 men) were enrolled 1 month poststroke (30+/-5 d); all patients concluded the rehabilitation program, which lasted 6 months.
  
  
  METHODS
  Barthel Index score, Hemiplegic Stroke Scale (HSS) score, and motor evoked potentials (MEPs) from the tibialis anterior muscle were performed 1, 4, and 7 months poststroke. The Wilcoxon signed-rank test, Mann-Whitney U test, and Spearman rank-order correlation coefficient were employed.
  
  
  METHODS
  The independence of gait defined as an HSS gait score of 3 or less (ability to walk without assistance apart from a stick or cane).
  
  
  RESULTS
  Patients with no recordable MEPs 1 month poststroke never regained walking ability; patients with MEPs of 8% or more (13.11+/-5.95) regained independent gait at discharge. It was not possible to predict walking capacity in patients with MEPs less than 8% (4.0+/-1.41). Four months postinjury, walking capacity was achieved only by the patients with MEPs of 18% or more (23.1+/-6.2).
  
  
  CONCLUSIONS
  In the postacute phase of stroke, the lower-limb MEP amplitudes could be a supportive tool for prognosis of lower-limb motor outcome.
authors.affiliation: Department of Neurorehabilitation, IRCCS, San Camillo Hospital, Alberoni, Italy.
authors.forename: Lamberto
authors.initials: L
authors.lastname: Piron
authors.forename: Franco
authors.initials: F
authors.lastname: Piccione
authors.forename: Paolo
authors.initials: P
authors.lastname: Tonin
authors.forename: Mauro
authors.initials: M
authors.lastname: Dam
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D004594:Electrophysiology; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D005684:Gait / Q000502:physiology*; D006429:Hemiplegia / Q000175:diagnosis* / Q000209:etiology / Q000534:rehabilitation*; D006801:Humans; D035002:Lower Extremity / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D026741:Physical Therapy Modalities; D011336:Probability; D011379:Prognosis; D020127:Recovery of Function; D012047:Rehabilitation Centers; D018570:Risk Assessment; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D020521:Stroke / Q000150:complications / Q000175:diagnosis; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome