[Use of rifabutin in cases of toxicity to rifampicin].
Rifampicin is an essential drug in the present treatment of tuberculosis. On some occasions, it cannot be used due to severe adverse effects. Rifabutin is a drug of the same family, with a similar activity and difference adverse effects. This study describes the beneficial results of the substitution of rifampicin with rifabutin in patients with severe toxicity.
Moreno González
B
B
Medicina Familiar y Salud Comunitaria Area 5, Madrid.
Rodríguez Blanco
A
A
Rodríguez Barrientos
R
R
Vidal Pérez
J L
JL
Noguerado Asensio
A
A
D000328:Adult; D000368:Aged; D000904:Antibiotics, Antitubercular / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017828:Rifabutin / Q000627:therapeutic use*; D012293:Rifampin / Q000009:adverse effects*; D014376:Tuberculosis / Q000188:drug therapy*
D000904:Antibiotics, Antitubercular; D017828:Rifabutin; D012293:Rifampin