Primary extraneural myxopapillary ependymoma of the broad ligament.
Primary extraneural ependymomas are rare tumors that arise in ectopic sites, including pulmonary, sacrococcygeal region, ovarian, and paraovarian tissues. Four such ependymomas reported in the literature involve the paraovarian tissues, including 2 broad ligament ependymomas. Here we describe a myxopapillary ependymoma of the broad ligament in a 22-year-old woman, which may be the first tumor of this type to be reported in this location. Cytology, histology, cytochemistry, immunohistochemistry, and flow cytometry ploidy analysis are studied and described. Identification of perivascular ependymal rosettes, ependymal canals, vimentin and glial fibrillary acidic protein immunoreactivity, cytochemical staining of blepharoplasts or terminal bars by phosphotungstic acid hematoxylin, and presence of multiple foci of myxoid degeneration among the ependymal rosettes characterized a myxopapillary ependymoma.
Whittemore
Darren E
DE
Department of Pathology, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236, USA. whittemore@bluebirdcom.net
Grondahl
Robert E
RE
Wong
Kondi
K
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001956:Broad Ligament / Q000737:chemistry / Q000473:pathology*; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D005350:Fibroma / Q000175:diagnosis; D005833:Genital Neoplasms, Female / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006106:Granulosa Cell Tumor / Q000175:diagnosis; D006801:Humans; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis
D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin