[Dynamics of the pathomorphological changes in cirrhotic liver in own material].
Cirrhosis is widely regarded as being irreversible end stage of many different chronic liver diseases. Recent studies have demonstrated that fibrosis end even cirrhosis may regress. In fact liver cirrhosis is a dynamic process involving hepatocellular injury, increased extracellular matrix synthesis, lobular structure distortion and nodular regeneration. The analysis of 157 patients with chronic hepatitis B or C who had at least two biopsies shown that liver fibrosis sometimes decreased but evident cirrhosis was reversible very rarely. The differences between patients HBV+ and HCV+ were not statistically significant.
Mietkiewski
Janusz
J
Zakład Patomorfologii Samodzielnego Publicznego, Wojewódzkiego Szpitala Zespolonego w Szczecinie.
D000328:Adult; D002648:Child; D018450:Disease Progression; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008103:Liver Cirrhosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology* / Q000821:virology; D011044:Poland / Q000453:epidemiology; D012074:Remission Induction; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D013997:Time Factors