Synthesis of bridgehead hydroxy bicyclo[2.2.2]octane derivatives.
Two independent synthetic routes, starting from 1,3-cyclohexadione, toward the 4-hydroxy bicyclo[2.2.2]octane-2,6-dione derivative 3 are described.
Thornqvist
Viveca
V
Division of Organic Chemistry, Kemicentrum, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.
Manner
Sophie
S
Wingstrand
Magnus
M
Frejd
Torbjörn
T
D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009795:Octanes / Q000138:chemical synthesis* / Q000737:chemistry
D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D009795:Octanes