The cerebellum communicates with the basal ganglia.
The cerebral cortex is interconnected with two major subcortical structures: the basal ganglia and the cerebellum. How and where cerebellar circuits interact with basal ganglia circuits has been a longstanding question. Using transneuronal transport of rabies virus in macaques, we found that a disynaptic pathway links an output stage of cerebellar processing, the dentate nucleus, with an input stage of basal ganglia processing, the striatum.
Hoshi
Eiji
E
Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.
Tremblay
Léon
L
Féger
Jean
J
Carras
Peter L
PL
Strick
Peter L
PL
D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology* / Q000821:virology; D002531:Cerebellum / Q000033:anatomy & histology* / Q000378:metabolism / Q000821:virology; D008251:Macaca; D009434:Neural Pathways / Q000033:anatomy & histology* / Q000821:virology; D011820:Rabies virus / Q000502:physiology