Acceptance of marginal liver donors increases the volume of liver transplant: early results of a single-center experience.
To expand the donor pool, clinicians are continually modifying criteria to accept organs, particularly those in the so-called expanded or marginal donor pool. The concept and definition of a marginal donors continues to evolve. The impact of their use is the result of a combination of donor and recipient factors. Most clinicians accept steatosis above 30%, donor age over 60 years, prolonged ischemia time, prolonged intensive care unit stay, hypernatremia, previous cardiac arrest, prolonged episodes of hypotension, large use of inotrope drugs, and elevated liver function tests as criteria for designation of a marginal organ. In June 2003, we started to use marginal donors each year tripling the number of transplants per year at our center.
Gruttadauria
S
S
Isituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione UPMC-Italy, Palermo, Italy. sgruttadauria@ismett.edu
Cintorino
D
D
Mandala'
L
L
Musumeci
A
A
Volpes
R
R
Vizzini
G B
GB
Palazzo
U
U
Spada
M
M
Verzaro
R
R
Gridelli
B
B
D002102:Cadaver; D006801:Humans; D008099:Liver / Q000033:anatomy & histology*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors / Q000600:supply & distribution*; D008875:Middle Aged; D018579:Patient Selection; D012189:Retrospective Studies; D014019:Tissue Donors; D016896:Treatment Outcome