title: Effects of surgical or chemical delaying procedures on the survival of proximal predicled venous island flaps: an experimental study in rats.
abstract: To increase the survival of proximally pedicled venous island flaps, which are known to be safe only when small, we used surgical and chemical delaying procedures both individually and in combination for 7, 14, and 21 days. Survival was 1% in those flaps designated as controls, in which there was neither surgical nor chemical delay. However, it was 3%, 31%, and 68% at 7, 14, and 21 days, respectively, when surgical delay was used and 16%, 56%, and 86%, at 7, 14, and 21 days, respectively, when chemical delay was used. Survival was 32%, 84%, and 87%, at 7, 14, and 21 days when both chemical and surgical delays were used. We conclude that chemical delay is more effective than surgical delay in increasing survival of proximally pedicled venous island flaps, but the use of combined chemical and surgical delay may reduce the time required for delay.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Atatürk Training and Research Hospital, Izmir, Turkey.
authors.forename: Nesrin Tan
authors.initials: NT
authors.lastname: Başer
authors.forename: Ozlem Karataş
authors.initials: OK
authors.lastname: Silistreli
authors.forename: Nejdet
authors.initials: N
authors.lastname: Sişman
authors.forename: Yücel
authors.initials: Y
authors.lastname: Oztan
mesh_terms: D000818:Animals; D066298:In Vitro Techniques; D005996:Nitroglycerin / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013524:Surgical Flaps / Q000098:blood supply / Q000502:physiology*; D013997:Time Factors; D014022:Tissue Survival / Q000187:drug effects / Q000502:physiology*; D014680:Veins / Q000601:surgery
chemical_list: D005996:Nitroglycerin