[Clinical study of acoustic densitometry technique in detecting atherosclerotic plaque].
OBJECTIVE
To investigate the effect of Quyu Xiaoban Capsule (QYXB) on the regressive treatment of atherosclerosis (AS) with acoustic densitometry (AD) technique.


METHODS
Eighty patients with AS were randomly divided into two groups, trial group was treated with QYXB and conventional medicine, and control group was treated with conventional medicine alone. Normal arterial wall and different types of atherosclerotic plaques were detected with AD technique before treatment and 10 months later.


RESULTS
The corrected averages in intimal echo intensity (AIIc%) were elevated in both groups but without significant difference, AIIc% of fatty plaques were increased in both groups and the value after treatment was significantly higher than that of pre-treatment in the trial group (68.12 +/- 5.54 vs 61.43 +/- 5.37, P < 0.05). The increment rate of AIIc% in trial group was significantly higher than that in control group (10.9 +/- 5.1% vs 2.5 +/- 5.5%, P < 0.05).


CONCLUSIONS
QYXB can stabilize the atherosclerotic plaque by increasing its acoustic density. Acoustic densitometry technique can differentiate the different histological plaques and monitor the histological changes of plaques during treatment.
Zhao
Yu-xia
YX
Department of Traditional Chinese Medicine, Qilu Hospital, Jinan 250012, China.
Liu
Yun-fang
YF
Yu
Hui-ming
HM
D000328:Adult; D000368:Aged; D001158:Arteries / Q000000981:diagnostic imaging* / Q000187:drug effects; D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D002214:Capsules; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D003720:Densitometry; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005263:Femoral Artery / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D014463:Ultrasonography
D002214:Capsules; D004365:Drugs, Chinese Herbal