A comparison of high and standard blood transfusion volumes in premature infants.
We compared high volume (20 ml/kg) with standard volume (15 ml/kg) packed red blood cell (PRBC) transfusions in a randomized trial. Ten high volume babies received a mean of 2.8 transfusions, while 10 standard volume babies received a mean of 3.4 (p=0.58). No adverse events were attributed to the use of the high volume transfusions.


CONCLUSIONS
Higher transfusion volumes appear to be well tolerated. The data can be used in the planning of larger controlled trials in VLBW infants.
Wong
Hubert
H
Department of Pediatrics, Queen's University, Kingston, Ontario, Canada.
Connelly
Robert
R
Day
Andrew
A
Flavin
Michael P
MP
D001803:Blood Transfusion / Q000379:methods*; D006400:Hematocrit; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature