[Clinical case of the month. Rendu-Osler-Weber disease: a rare case of stroke in the young].
Rendu-Osler disease or hereditary hemorragic telangiectasia is a group of autosomal dominant diseases characterized by angiodysplasic lesions in the skin, mucous membranes and viscera with risks of recurrent bleedings. Neurological complications have been described in 10-30% of these patients, most often hemorrhagic or septic. More exceptionally, ischemic strokes occur in these patients, particularly if they have pulmonary arteriovenous malformations. We report the observation of a 25 year old man who developed a latero-protuberantial stroke. The explorations revealed pulmonary AV malformations and nasal telangiectasias that led to the diagnostic of Rendu-Osler disease. This affection should be considered as a potential cause of cerebral ischemic attack, particularly in young patients without risk factors.
Leclercq
P
P
Service de Rhumatologie, CHU Sart Tilman, Liège.
Thomas
A
A
Sadzot
B
B
D000328:Adult; D001165:Arteriovenous Malformations / Q000175:diagnosis; D006801:Humans; D008297:Male; D011651:Pulmonary Artery / Q000002:abnormalities; D011667:Pulmonary Veins / Q000002:abnormalities; D020521:Stroke / Q000209:etiology*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis*