[Effect of compound nonoxinol on the inhibition of bacteria in vitro].
OBJECTIVE
To study the effect of compound nonoxinol on the inhibition of bacteria in vitro.


METHODS
The minimal bactericidal concentration (MBC) and minimal bactericidal time (MBT) of nonoxinol providine iodine and compound nonoxinol, composed of nonoxinol and providine iodine were determined by inhibiting C. albicans and N. gonorrhoeae.


RESULTS
Nonoxinol alone showed no inhibiting effects on bacteria. The MBT was 2 minutes for both compound nonoxinol and providine iodine, but the MBC of providine iodine was higher than that of compound nonoxinol.


CONCLUSIONS
Compound nonoxinol works better in inhibiting bacteria than either nonoxinoother or providine iodine used alone.
Cao
Jie
J
Department of Microbiology, School of Basic Medical Science, Peking University, Beijing 100083, China. caojie3040776@sina.com
Li
Wei-dong
WD
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D017137:Nonoxynol / Q000494:pharmacology*; D011206:Povidone-Iodine / Q000494:pharmacology*
D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D017137:Nonoxynol; D011206:Povidone-Iodine