title: Dissolution of ureteral uric acid calculi with local litholytic irrigation.
abstract: This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radiography (KUB), retrograde urography, ultrasonography (B-mode ultrasound), spiral computerized tomography(CT) and blood biochemical examinations. A ureteral catheter was passed retrogradely across ureteral calculi by cystoscopy. LLI with tromethamine-E (THAM-E) was performed via the ureteral catheter after the improvement of renal function and general situation and the control of urinary tract infection under the condition of intravenous application of antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones, 13 cases within 10 days and 1 within 12 days. Mild hematuria was observed in the majority of the cases and temporary aggravated lumbago in 1 case, with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral uric acid calculi for its advantages of shorter duration,lower cost, less physical suffering and no severe complications.
authors.affiliation: Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Chen
authors.forename: Linfang
authors.initials: L
authors.lastname: Yao
authors.forename: Zhangqun
authors.initials: Z
authors.lastname: Ye
authors.forename: Weimin
authors.initials: W
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D011189:Potassium Chloride / Q000008:administration & dosage; D012965:Sodium Chloride / Q000008:administration & dosage; D007507:Therapeutic Irrigation / Q000379:methods; D014325:Tromethamine / Q000008:administration & dosage; D014514:Ureteral Calculi / Q000737:chemistry / Q000628:therapy*; D014527:Uric Acid; D014546:Urinary Catheterization
chemical_list: D014325:Tromethamine; D014527:Uric Acid; D012965:Sodium Chloride; D011189:Potassium Chloride