Severe action tremor related to interferon-alpha 2b therapy for malignant melanoma.
Interferon (IFN)-alpha 2b is used for adjuvant therapy in malignant melanoma. Neurotoxicity as a side effect has been well described. Resting and action tremor related to interferon have been reported but are relatively uncommon. We report a case of a delayed-onset interferon-related action tremor in a patient with malignant melanoma.
Nishihori
Taiga
T
Department of Medicine, Beth Israel Medical Center, New York, NY, USA. taiganishihori@yahoo.co.jp
Abdo-Matkiwsky
May
M
Fleishman
Stewart B
SB
Blum
Ronald H
RH
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects*; D008545:Melanoma / Q000188:drug therapy*; D011994:Recombinant Proteins; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000188:drug therapy*; D014202:Tremor / Q000139:chemically induced*
D000970:Antineoplastic Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins