An oxidatively releasable caging group that senses lipid peroxidation.
A new radical-sensitive caging technique releases a caged molecule under lipid peroxidation conditions. In a competitive oxidation study with a model lipid, methyl linoleate, the oxidatively releasable xanthenyl caging groups is found to be 1.93+/-0.55 times more reactive than the lipid model compound.
Trumbull
Kari A
KA
Department of Chemistry, University of Oregon, Eugene, OR 97403, USA.
Branchaud
Bruce P
BP
D015374:Biosensing Techniques; D008041:Linoleic Acids / Q000737:chemistry*; D015227:Lipid Peroxidation; D010084:Oxidation-Reduction; D014966:Xanthenes
D008041:Linoleic Acids; D014966:Xanthenes; C005575:methyl linoleate