title: [A vasoactive peptide: urotensin II].
abstract: Urotensin II (U II ) is currently the most potent vasoconstrictor. G-protein coupled receptor 14 ( GPR-14) is its specific receptor. This review mainly discribes the structure and distribution of U II and GPR14, the activities that U II and GPR14 stimulates proliferation of vascular smooth muscle cells and vasoconstriction, as well as its mechanism.
authors.affiliation: Department of Endocrinology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Liu
authors.forename: Zheng-Pei
authors.initials: ZP
authors.lastname: Zeng
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D014579:Urotensins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D014662:Vasoconstrictor Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology
chemical_list: D043562:Receptors, G-Protein-Coupled; C121697:UTS2R protein, human; D014579:Urotensins; D014662:Vasoconstrictor Agents; C029677:urotensin II