Time-resolved reflectance at null source-detector separation: improving contrast and resolution in diffuse optical imaging.
We propose a novel approach to imaging in diffusive media based on time-resolved reflectance measurements at null source-detector separation. This approach yields better spatial resolution and contrast as compared to the classical approach, which typically employs a separation of 20-40 mm. Results are obtained by an analytical perturbation approach to diffusion theory and on Monte Carlo simulations. Practical implementation with state-of-the-art technology and performance of a complementary approach based on the use of small but not null source-detector separation are also discussed.
Torricelli
Alessandro
A
CNR-INFM and CNR-IFN, Politecnico di Milano--Dipartimento di Fisica, Italy.
Pifferi
Antonio
A
Spinelli
Lorenzo
L
Cubeddu
Rinaldo
R
Martelli
Fabrizio
F
Del Bianco
Samuele
S
Zaccanti
Giovanni
G