Centile values for serum lipids and blood pressure for Asian Indian adolescents.
BACKGROUND
Reference data for plasma lipids and blood pressure are not available for Asian Indian adolescents. This study aimed to develop representative age- and sex- specific percentile reference data for serum lipids [total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), non-HDL cholesterol] and blood pressure for urban Asian Indian adolescents aged 14-18 years. The sample consisted of 680 boys and 521 girls aged 14-18 years from the cross-sectional population survey, Epidemiological Study of Adolescents and Young Adults (ESAY) for whom the data for serum lipid levels and blood pressure were recorded. Smoothed age- and sex- specific 5th, 10th, 25th, 50th, 75th, 85th, 90th and 95th percentiles where derived using LMS regression.


RESULTS
Percentile-based reference data for serum lipids and blood pressure are presented for adolescent Asian Indian boys and girls for the first time. Asian Indian adolescents had lower levels of serum TC, LDL-C and HDL-C and higher TG than their counterparts in the USA. Interesting trends in TC and HDL-C levels where observed, which might reflect changes in dietary pattern and physical activity in this age group in India.


CONCLUSIONS
These reference data could be used to identify adolescents with an elevated risk of developing dyslipidemia, hypertension and cardiovascular disorders, to plan and implement preventive policies, and to study temporal trends.
Madhavan
Malini
M
Department of Medicine, All India Institute of Medical Sciences, New Delhi-110029, India. malini_madhavan@yahoo.co.in
Pandey
Ravindra M
RM
Misra
Anoop
A
Vikram
Naval K
NK
Dhingra
Vibha
V
Luthra
Kalpana
K
Wasir
Jasjeet S
JS
D000293:Adolescent; D044466:Asian People; D001794:Blood Pressure; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004032:Diet; D005260:Female; D006801:Humans; D007194:India; D008055:Lipids / Q000097:blood*; D008297:Male; D009043:Motor Activity; D012016:Reference Values; D014280:Triglycerides / Q000097:blood; D014481:United States
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol