Critical assessment of methods of protein structure prediction (CASP)--round 6.
This article is an introduction to the special issue of the journal Proteins, dedicated to the sixth CASP experiment to assess the state of the art in protein structure prediction. The article describes the conduct of the experiment and the categories of prediction included, and outlines the evaluation and assessment procedures. A brief summary of progress over the decade of CASP experiments is also provided.
Moult
John
J
Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland.
Fidelis
Krzysztof
K
Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California.
Rost
Burkhard
B
CUBIC, Columbia University, Department of Biochemistry and Molecular Biophysics, New York, New York.
Hubbard
Tim
T
Sanger Institute, Wellcome Trust Genome Campus, Cambridgeshire, United Kingdom.
Tramontano
Anna
A
Istituto Pasteur-Fondazione Cenci Bolognetti, University of Rome "La Sapienza," Rome, Italy.
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D008958:Models, Molecular; D015233:Models, Statistical; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods*; D020539:Sequence Analysis, Protein
D011506:Proteins