title: Long-term effect of bone marrow transplantation in adult-onset adrenoleukodystrophy.
abstract: We report a long-term outcome of motor function in a patient with adult-onset adrenoleukodystrophy after bone marrow transplantation (BMT). Clinically motor function gradually improved and became almost normal in 2 years after BMT. Serial transcranial magnetic stimulation showed gradual improvement of central motor conduction until 1 year after BMT, and then it became stable. Central motor conduction time and motor threshold were useful for monitoring the central motor function in this patient.
authors.affiliation: Department of Neurology, Kyoto University Hospital, Kyoto, Japan. hitomi46@kuhp.kyoto-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Hitomi
authors.forename: T
authors.initials: T
authors.lastname: Mezaki
authors.forename: H
authors.initials: H
authors.lastname: Tomimoto
authors.forename: A
authors.initials: A
authors.lastname: Ikeda
authors.forename: S
authors.initials: S
authors.lastname: Shimohama
authors.forename: T
authors.initials: T
authors.lastname: Okazaki
authors.forename: T
authors.initials: T
authors.lastname: Uchiyama
authors.forename: H
authors.initials: H
authors.lastname: Shibasaki
mesh_terms: D000326:Adrenoleukodystrophy / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D016026:Bone Marrow Transplantation / Q000379:methods*; D004558:Electric Stimulation / Q000379:methods; D019054:Evoked Potentials, Motor / Q000502:physiology; D006801:Humans; D008297:Male; D013995:Time; D013997:Time Factors