[The influence of antidepressive therapy on short-term prognosis in elderly patients with unstable angina and depression].
OBJECTIVE
To observe the influence of antidepressive therapy on short-term prognosis in elderly unstable angina pectoris patients with depression.


METHODS
76 unstable angina pectoris patients were random into a therapy group (38) and control group (38). Patients in the therapy group were treated with psychotherapy and administration of antidepressant Fluoxetine (Prozac Eli Lilly, USA) 20mg once a day on the basis of regular cardiac medicine therapy for 12 weeks, Patients in the control group were only treated with regular cardiac medicine therapy.


RESULTS
Myocardial ischaemia in the therapy group was significantly improved. The recurrence rate of angina pectoris and incidence ratio of acute myocardial infarction in the therapy group were low. There was significant difference in comparison with the control group (P < 0.05).


CONCLUSIONS
Antidepression can significantly improve the short-term prognosis in elderly unstable angina pectoris patients.
Zeng
W
W
Division of Cardiology, Cardiovascular Medical Department, The First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China.
Ma
H
H
Liang
Q
Q
Dong
Y
Y
Ye
H
H
Zhang
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000523:psychology / Q000628:therapy*; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000209:etiology / Q000628:therapy*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011379:Prognosis; D011613:Psychotherapy
D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine