Overweight and obesity in deltaF508 homozygous cystic fibrosis.
Overweight (9%) and obesity (1%) in patients with cystic fibrosis homozygous for the deltaF508 mutation (CFdeltaF508) were non-trivial. Children with CFdeltaF508, in contrast to the general population, showed a positive association between body mass index and lung function for all body mass index z-scores.
Kastner-Cole
Dagmar
D
Division of Maternal and Child Health Sciences, Institute of Cardiovascular Research and Biomedical Research Centre, Ninewells Hospital, Dundee, Scotland, United Kingdom.
Palmer
Colin N A
CN
Ogston
Simon A
SA
Mehta
Anil
A
Mukhopadhyay
Somnath
S
D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000235:genetics / Q000503:physiopathology*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D005260:Female; D005541:Forced Expiratory Volume; D006720:Homozygote; D006801:Humans; D007223:Infant; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D009765:Obesity / Q000150:complications* / Q000503:physiopathology*
C505032:CFTR protein, human; C093349:cystic fibrosis transmembrane conductance regulator delta F508; D019005:Cystic Fibrosis Transmembrane Conductance Regulator