[Antiatherosclerotic hopes of calcium channel blockers].
The antiatherosclerotic effects of a calcium channel blockers have been attracting attention for some time. It is shown by the animal studies that especially dihydropyridine calcium channel blockers have the antiatherosclerotic effects by an anti-oxidative properties and the direct action on vascular cells in addition to an original decrease blood pressure, and the validity is being further proved by the results of randomized clinical trials such as PREVENT and CAMELOT.
Uetake
Yuzaburo
Y
Graduate school of Medicine, Department of Internal Medicine, Nephrology and Endocrinology, The University of Tokyo.
Shimosawa
Tatsuo
T
D000818:Animals; D001161:Arteriosclerosis / Q000517:prevention & control*; D002121:Calcium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D016032:Randomized Controlled Trials as Topic
D002121:Calcium Channel Blockers