Applications of derivative UV spectrophotometry for the determinations of fenbufen and ketoprofen in pharmaceutical preparations.
A methods for the determination of fenbufen and ketoprofen in pharmaceuticals by classical spectrophotometry--zero order derivative, first and second order derivatives spectrophotometry is described. using "peak-peak" (P-P) and, "peak-zero" (P-O) measurements. The calibration curves are linear within the concentration range of 2.0 - 12.0 microg x mL(-1) for fenbufen and ketoprofen. The procedure is simple, rapid and the results are reliable.
Pomykalski
Arkadiusz
A
Department of Medicinal Chemistry, Faculty of Pharmacy Prof. Skubiszewski Medical University of Lublin, 6 Chodźki Str., 20-093 Lublin, Poland.
Hopkała
Hanna
H
D007660:Ketoprofen / Q000032:analysis*; D010654:Phenylbutyrates / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D013607:Tablets
D010654:Phenylbutyrates; D013607:Tablets; D007660:Ketoprofen; C010725:fenbufen