Acquired ichthyosis and hypertrichosis due to autoimmune thyroiditis: therapeutic response to thyroxine replacement.
Thyroid diseases may be associated with a wide variety of dermatologic disorders. We report a 15-year-old girl with acquired ichthyosis and hypertrichosis associated with hypothyroidism resulting from autoimmune thyroiditis. Her skin lesions progressively resolved after 8 months of replacement therapy with L-thyroxine. This result supports the hypothesis that hypothyroidism in our patient can be directly related to the pathogenesis of acquired ichthyosis and hypertrichosis.
Brazzelli
Valeria
V
Department of Dermatology, University of Pavia, Policlinico S. Matteo-IRCCS, Pavia, Italy. vbrazzelli@libero.it
Prestinari
Francesca
F
Barbagallo
Tania
T
Bellani
Eleonora
E
Calcaterra
Valeria
V
Larizza
Daniella
D
Lauriola
Maria M
MM
Borroni
Giovanni
G
D000293:Adolescent; D005260:Female; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D006983:Hypertrichosis / Q000188:drug therapy / Q000209:etiology*; D007037:Hypothyroidism / Q000188:drug therapy / Q000209:etiology*; D007057:Ichthyosis / Q000188:drug therapy / Q000209:etiology*; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D013974:Thyroxine / Q000627:therapeutic use*; D016896:Treatment Outcome
D006728:Hormones; D013974:Thyroxine