title: Identification and heritability of fumonisin insensitivity in Zea mays.
abstract: Landraces of maize (Zea mays ssp. mays) and its wild teosinte relatives (Zea mays spp. parviglumis and mexicana) were surveyed for sensitivity to fumonisin B(1), a phytotoxin produced by the maize pathogen Gibberella moniliformis. Only two of 42 Z. mays samples were highly insensitive to FB(1) (ED(50) = ca. 200 microM). The teosintes and 76% of the maize landraces were moderately or highly sensitive to FB(1) (ED(50) < or = 30 microM), which indicates that FB(1) sensitivity is likely to be an ancestral trait in Z. mays. F(1) generations derived from crosses between FB(1)-sensitive maize inbred B73 and insensitive landraces were significantly less sensitive than B73. Thus, our data indicate that FB(1)-insensitivity is a relatively rare but heritable trait in maize. We also report the sensitivity of maize to other Gibberella toxins - beauvericin, diacetoxyscirpenol, and moniliformin.
authors.affiliation: National Center for Agricultural Utilization Research, United States Department of Agriculture, Peoria, IL 61604, USA. desjarae@ncaur.usda.gov
authors.forename: Anne E
authors.initials: AE
authors.lastname: Desjardins
authors.forename: Ronald D
authors.initials: RD
authors.lastname: Plattner
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Stessman
authors.forename: Susan P
authors.initials: SP
authors.lastname: McCormick
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Millard
mesh_terms: D003503:Cyclobutanes / Q000494:pharmacology; D047630:Depsipeptides / Q000494:pharmacology; D037341:Fumonisins / Q000494:pharmacology*; D020022:Genetic Predisposition to Disease; D005828:Genetics, Population; D005874:Gibberella / Q000472:pathogenicity; D006576:Heterocyclic Compounds, 4 or More Rings / Q000494:pharmacology; D003313:Zea mays / Q000187:drug effects* / Q000235:genetics*
chemical_list: C506431:4,15-diacetoxyscirpenol; D003503:Cyclobutanes; D047630:Depsipeptides; D037341:Fumonisins; D006576:Heterocyclic Compounds, 4 or More Rings; C004456:beauvericin; C008539:moniliformin; C056933:fumonisin B1