Characteristics of hyperthermia and its complications in patients with Prader Willi syndrome.
BACKGROUND
Thermoregulation problems, resulting in hypo- or hyperthermia, have been infrequently reported in children with Prader Willi syndrome (PWS), yet their clinical details remained unknown.


METHODS
The clinical characteristics of three infants with PWS are reported.


RESULTS
Etiologies of high fever could not be identified in three children with PWS. One of these children was also admitted to the intensive care unit with extremely high body temperature in a life-threatening condition, similar to septic shock, without a plausible explanation.


CONCLUSIONS
Hyperthermia may be a part of the clinical spectrum in young infants with PWS and should be carefully monitored, since it may cause life-threatening complications.
Ince
Erdal
E
Division of Pediatric Infectious Disease, Department of Pediatrics, Ankara Univeristy School of Medicine, Dikimevi, Ankara, Turkey. ince@dialup.ankara.edu.tr
Ciftçi
Ergin
E
Tekin
Mustafa
M
Kendirli
Tanil
T
Tutar
Ercan
E
Dalgiç
Nazan
N
Oncel
Selim
S
Dogru
Ulker
U
D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D011218:Prader-Willi Syndrome / Q000150:complications*