title: A highly potassium-selective ratiometric fluorescent indicator based on BODIPY azacrown ether excitable with visible light.
abstract: [structure: see text] A potassium-selective fluorescent BODIPY-linked azacrown ether chemosensor has been synthesized using novel substitution reactions of 3,5-dichloroBODIPY. The indicator absorbs and emits light in the visible wavelength range. The dissociation constant Kd for the complex between K+ and the probe is 0.5 mM in acetonitrile. Quantum chemical calculations show that the experimental hypsochromic shifts in absorption and fluorescence upon potassium binding are due to complexation, which induces a large conformational change of the sensor.
authors.affiliation: Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
authors.forename: Mukulesh
authors.initials: M
authors.lastname: Baruah
authors.forename: Wenwu
authors.initials: W
authors.lastname: Qin
authors.forename: Renaud A L
authors.initials: RA
authors.lastname: Vallée
authors.forename: David
authors.initials: D
authors.lastname: Beljonne
authors.forename: Taoufik
authors.initials: T
authors.lastname: Rohand
authors.forename: Wim
authors.initials: W
authors.lastname: Dehaen
authors.forename: Noël
authors.initials: N
authors.lastname: Boens
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D043844:Crown Ethers / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008027:Light; D008958:Models, Molecular; D015394:Molecular Structure; D011188:Potassium / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D043844:Crown Ethers; D005456:Fluorescent Dyes; D011188:Potassium