Choanal atresia - a recurrent feature of foetal carbimazole syndrome.
Choanal atresia is described as a feature of several congenital anomaly phenotypes. Most cases of choanal atresia arises as an isolated clinical finding. In utero exposure to carbimazole for maternal hyperthyroidism has been reported in five cases of choanal atresia. We report another instance of this teratogenic cause of choanal atresia. Maternal drug history is an important aspect of assessment in cases of choanal atresia.
Myers
A K
AK
The National Centre for Medical Genetics, Our Ladys Hospital for Sick Children, Crumlin, Dublin, Ireland. willie.reardon@olhs.edu
Reardon
W
W
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis*; D013956:Antithyroid Agents / Q000009:adverse effects*; D002231:Carbimazole / Q000009:adverse effects*; D002754:Choanal Atresia / Q000139:chemically induced* / Q000175:diagnosis*; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009558:Nipples / Q000002:abnormalities; D013577:Syndrome
D013956:Antithyroid Agents; D002231:Carbimazole