Diabetes mellitus following pituitary adenomectomy in euglycemic patients with acromegaly.
Insulin resistance, impaired glucose tolerance and diabetes mellitus (DM) secondary to acromegaly generally improve following treatment of the underlying disease. In rare cases, in spite of normoglycaemia in the presence of active acromegaly, patients develop diabetes mellitus following pituitary adenomectomy to the extent of requiring insulin therapy. We report 7 patients who developed diabetes mellitus after pituitary adenomectomy. Regular measuring of blood glucose in post-pituitary surgery patients is recommended as a necessary step even in the previously normoglycaemics.
Larijani
Bagher
B
Endocrinology and Metabolism Research Centre (EMRC), Tehran University of Medical Sciences (TUMS), Iran. emrc@sina.tums.ac.ir
Nakhjavani
Manouchehr
M
Baradar-Jalili
Reza
R
Akrami
Seyed Mohammad
SM
Bandarian
Fatemeh
F
D000172:Acromegaly; D000236:Adenoma / Q000150:complications* / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D003920:Diabetes Mellitus / Q000209:etiology*; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008297:Male; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D010911:Pituitary Neoplasms / Q000150:complications* / Q000601:surgery*; D012189:Retrospective Studies
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone