Analysis of the structure of magnetic fields that induced inhibition of stimulated neurite outgrowth.
The important experiments showing nonlinear amplitude dependences of the neurite outgrowth in pheochromocytoma nerve cells due to ELF magnetic field exposure had been carried out in a nonuniform ac magnetic field. The nonuniformity entailed larger than expected variances in magnetic field magnitudes associated with specific levels of biological effects, thereby evoking a question about validity of the interpretations formulated for the case of a uniform field. In this work, we calculate the relative value of nonuniformity and deviations in ac magnetic field. It is shown that these factors do not affect the main conclusion in the original papers about the form of the amplitude dependence of the observed biological effect.
Binhi
V N
VN
General Physics Institute RAS, Moscow, Russia. vb@biomag.info
Blackman
C F
CF
D000818:Animals; D008280:Magnetics; D016501:Neurites; D016716:PC12 Cells; D051381:Rats