title: Systolic right ventricular function assessment by pulsed wave tissue Doppler imaging of the tricuspid annulus.
abstract: BACKGROUND
  Systolic right ventricular (RV) function is an important predictor in the course of various congenital and acquired heart diseases. So far, tricuspid annular motion velocity in systole as obtained by pulsed wave tissue Doppler imaging (TDI) has rarely been investigated for RV function assessment in a sizeable adult patient population.
  
  
  METHODS
  258 individuals were included in the study. Among them, there were 107 individuals without cardiovascular disease, 71 patients with predominant RV dysfunction, 40 patients with pulmonary artery hypertension, and 40 patients with predominant left ventricular dysfunction. The reference methods for RV systolic function assessment were biplane two-dimensional echocardiography and magnetic resonance imaging (MRI; n = 31) for the calculation of RV ejection fraction (EF). Lateral tricuspid valve annular motion velocities in systole (TVlat, cm/s) were recorded using pulsed wave TDI from the apical 4-chamber view (long axis function).
  
  
  RESULTS
  RV EF as determined by biplane echocardiography correlated significantly with respective values as assessed by MRI: RVEFecho = RV EFMRI + 1.6; r2 = 0.569, p <0.0001. Using the best TVlat threshold of 12 cm/s, distinction between the group with RV dysfunction and the other groups was possible with 86% sensitivity and 83% specificity. There was a direct and significant correlation between TVlat and RV ejection fraction (p <0.0001). Using TVlat thresholds of 12 and 9 cm/s, distinction between normal RV EF (>55%), moderately reduced (30-55%) and severely reduced RV EF (<30%) was possible with 84% sensitivity and 81% specificity, respectively with 83% sensitivity and 67% specificity.
  
  
  CONCLUSIONS
  Systolic long axis velocity measurement of the lateral tricuspid annulus is useful and accurate to assess RV systolic function in a broad patient population. Thresholds of 12 and 9 cm/s allow differentiation between normal, moderately reduced and severely reduced RV ejection fraction.
authors.affiliation: Department of Cardiology, University Hospital, Berne, Switzerland.
authors.forename: David
authors.initials: D
authors.lastname: Tüller
authors.forename: Martin
authors.initials: M
authors.lastname: Steiner
authors.forename: Andreas
authors.initials: A
authors.lastname: Wahl
authors.forename: Marika
authors.initials: M
authors.lastname: Kabok
authors.forename: Christian
authors.initials: C
authors.lastname: Seiler
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume; D013557:Switzerland; D014261:Tricuspid Valve / Q000648:ultrastructure*; D018497:Ventricular Dysfunction, Right / Q000175:diagnosis / Q000000981:diagnostic imaging*