title: Congenital factor VII deficiency: a case report.
abstract: Factor VII deficiency is a rare congenital blood disorder. Its clinical features are rather variable and ranges from epistaxis to massive intracranial haemorrhage. Treatment involves replacement therapy, which constitutes use of fresh frozen plasma, prothrombin complex concentrates or recombinant activated factor VII. Although it is a rare entity, one still needs to consider it as a probable diagnosis in a newborn with coagulopathy. We report here a case of Factor VII deficiency in a newborn who presented with subdural haemorrhage at day 4 of life.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
authors.forename: L
authors.initials: L
authors.lastname: Zarina
authors.forename: A
authors.initials: A
authors.lastname: Hamidah
authors.forename: J
authors.initials: J
authors.lastname: Rohana
authors.forename: A K
authors.initials: AK
authors.lastname: Faraizah
authors.forename: A A
authors.initials: AA
authors.lastname: Noryati
authors.forename: R
authors.initials: R
authors.lastname: Jamal
authors.forename: N Y
authors.initials: NY
authors.lastname: Boo
mesh_terms: D016913:Blood Component Transfusion; D005168:Factor VII Deficiency / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D006408:Hematoma, Subdural / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010949:Plasma; D014057:Tomography, X-Ray Computed