Epigallocatechin gallate inhibits biofilm formation by ocular staphylococcal isolates.
Epigallocatechin gallate (EGCg), the main polyphenol component of green tea, has several antibacterial properties. Here we show that sub-MICs of EGCg appear to decrease slime production, therefore inhibiting biofilm formation by ocular staphylococcal isolates previously characterized for the presence of ica genes by the Congo red agar plate assay and for adhesion to microtiter plates.
Blanco
Anna Rita
AR
Direzione Ricerca Sviluppo & Innovazione, SIFI SpA, Catania, Italy.
Sudano-Roccaro
Andrea
A
Spoto
Giovanna Carmela
GC
Nostro
Antonia
A
Rusciano
Dario
D
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D002392:Catechin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D005123:Eye / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013212:Staphylococcus epidermidis / Q000187:drug effects* / Q000302:isolation & purification / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D002392:Catechin; C045651:epigallocatechin gallate