title: [Clinically significant drug-drug and drug-food interactions associated with calcium channel blockers].
abstract: Calcium channel blockers have been widely used for treatment of hypertension, angina pectoris, arrhythmia, and other heart diseases. Nowadays, combination therapy is widely common for these diseases. However, combination therapy is associated with increasing risks of pharmacokinetic or pharmacodynamic drug-drug interaction, and therefore clinicians should pay attention to prevent it. Furthermore, in addition to drug-drug interactions, we need to be cautions for drug interaction with food and drink including health-food and supplement.
authors.affiliation: Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Imaura
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ohno
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Nakajima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D002121:Calcium Channel Blockers / Q000009:adverse effects*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D018565:Food-Drug Interactions; D006801:Humans
chemical_list: D002121:Calcium Channel Blockers