[Quantitative characteristics of stromal components in prognosis of ovarian cancer recurrences].
Surgical material and biopsies from 98 patients with ovarian carcinoma of serous histological type were used for the study. Tumor relapse was diagnosed in 24 patients. Quantimetry was done at the Leica Reichert Polivar 2 with the help of analysis Quantiment 500 C (Leica). Malignant epithelial neoplasms of a serous histological type with low stroma volume and necrotic changes in the tumor node, low density of vascularization, a low level of angiogenesis, pronounced collagen disorganization and fibroblast and fibrocyte prevailing in the cell microenvironment had a high risk of relapse.
Novichkov
E V
EV
Votintsev
A A
AA
D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D011379:Prognosis; D012008:Recurrence; D017154:Stromal Cells / Q000473:pathology