Math-Map(ic)s.
In this issue of Neuron, Wang et al. and Machold and Fishell present contrasting molecular fate maps of Math1, which redefine the derivatives of the embryonic rhombic lip and offer a conceptual overhaul of cerebellar and precerebellar development. These fate maps identify a common developmental thread linking diverse, functionally associated neurons and reveal an exquisite temporal organization in cell production within a precise spatially defined region of neuroepithelium.
Wingate
Richard
R
MRC Centre for Developmental Neurobiology, King's College London, London SE1 1UL, United Kingdom.
D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins / Q000378:metabolism*; D002531:Cerebellum / Q000166:cytology* / Q000196:embryology / Q000378:metabolism; D047108:Embryonic Development; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D009474:Neurons / Q000378:metabolism*
D051792:Basic Helix-Loop-Helix Proteins; C500943:Atoh1 protein, mouse