title: First successful implantation of a biodegradable metal stent into the left pulmonary artery of a preterm baby.
abstract: Stent implantation in the youngest patients with a congenital heart disease implicates limitations concerning further vessel growth, the need of staged redilation, and later surgical removal. The search to overcome these restrictions led to open stent designs, with a wide adaptability to the vessel growth and recently to the development of bioabsorbable stent materials. A preterm baby born at 26 weeks of gestation was referred to our clinic following inadvertent ligation of the left pulmonary artery. Despite efficient debanding, the left lung perfusion was absent. Implantation of a biodegradable 3 mm magnesium stent was performed in a hybrid procedure when the baby weighed 1.7 kg. Reperfusion of the left lung was established and persisted throughout the 4-month follow-up period during which the gradual degradation process of the stent completed. Additional interventions, should they become necessary, seem not to be limited. Despite the small size of the baby, the degradation process was clinically well tolerated. The mechanical and degradation characteristics of the magnesium stent proved to be adequate to secure reperfusion of the previously occluded left pulmonary artery. Bioabsorbable stents with different diameters may help develop new strategies in the therapy of vessel stenosis in pediatric patients.
authors.affiliation: Deutsches Kinderherzzentrum Sankt Augustin, Sankt Augustin, Germany. p.zartner@asklepios.com
authors.forename: Peter
authors.initials: P
authors.lastname: Zartner
authors.forename: Robert
authors.initials: R
authors.lastname: Cesnjevar
authors.forename: Helmut
authors.initials: H
authors.lastname: Singer
authors.forename: Michael
authors.initials: M
authors.lastname: Weyand
mesh_terms: D020341:Absorbable Implants; D000792:Angiography; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008274:Magnesium; D011474:Prosthesis Design; D011651:Pulmonary Artery / Q000002:abnormalities / Q000601:surgery*; D015607:Stents
chemical_list: D008274:Magnesium