title: Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.
abstract: An examination of several amine-substituted analogs of N(1)-benzenesulfonylindoles reveals that although they bind at human 5-HT(6) serotonin receptors with high affinity, they are likely to bind in a dissimilar manner.
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298-0540, USA.
authors.forename: Manik
authors.initials: M
authors.lastname: Pullagurla
authors.forename: Uma
authors.initials: U
authors.lastname: Siripurapu
authors.forename: Renata
authors.initials: R
authors.lastname: Kolanos
authors.forename: Mikhail L
authors.initials: ML
authors.lastname: Bondarev
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Dukat
authors.forename: V
authors.initials: V
authors.lastname: Setola
authors.forename: B L
authors.initials: BL
authors.lastname: Roth
authors.forename: Richard A
authors.initials: RA
authors.lastname: Glennon
mesh_terms: D000588:Amines / Q000737:chemistry; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D011485:Protein Binding; D011985:Receptors, Serotonin / Q000737:chemistry*
chemical_list: D000588:Amines; D007211:Indoles; D011985:Receptors, Serotonin; C097216:serotonin 6 receptor