[Diterpenes constituents of Tripterygium wilfordii].
OBJECTIVE
To study the chemical constituents of Tripterygium wilfordii Hook. F.


METHODS
Various column chromatographies with silica gel were used for the isolation and purification. The structures of compounds were established on the basis of its IR, MS, UV, 1H NMR, 13C NMR and HRMS, 1H-1H COSY, 1H-13C COSY and NOESY.


RESULTS
Four diterpenoids were isolated: 16-hydroxytriptolide (I), triptolidenol (II), tripdiolide (III), 2-epitripdiolide (IV).


CONCLUSIONS
Compound IV is a new diterpenoid.
Lin
Sui
S
Fujian Institute of Medical Sciences, Fuzhou 350001, China. linsui-syy@sina.com
Yu
Xian-Yong
XY
Que
Hui-Qing
HQ
Chen
Zhong
Z
Xie
Di-Lin
DL
Li
Yuan-Chao
YC
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D029757:Tripterygium / Q000737:chemistry*
C517471:2-epitripdiolide; D004224:Diterpenes; C076300:16-hydroxytriptolide; C001898:tripdiolide