Patterns of mandibular invasion by gingival squamous cell carcinoma.
OBJECTIVE
This study examined patterns of invasion of lower gingiva cancer into the mandible. Our goal was to clarify the most common routes for gingival squamous cell carcinoma to enter and spread within the mandible.


METHODS
The subjects were 176 patients with lower gingival squamous cell carcinoma who underwent mandibulectomy; all tumors were examined histopathologically. The method of mandibulectomy was decided on the basis of conventional plain radiographic and computed tomographic findings.


RESULTS
The tumor extended to the periosteum in 33%, to the cortical bone in 23%, and to the bone marrow in 9% of the patients who underwent mandibular resection. The remaining 35% of our patients had no evidence of mandibular invasion.


CONCLUSIONS
The area of bone resorption on preoperative clinical and radiographic examinations often disagreed with the extent of mandibular invasion on histopathologic examination.
Nomura
Takeshi
T
Department of Oral and Maxillofacial Surgery, Tokyo Dental College, 1-2-2 Masago, Mihamaku, Chiba 261-8502, Japan.
Shibahara
Takahiko
T
Cui
Nian-Hui
NH
Noma
Hiroyasu
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D005887:Gingival Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D019647:Oral Surgical Procedures / Q000379:methods; D011859:Radiography