title: Acquired ichthyosis and hypertrichosis due to autoimmune thyroiditis: therapeutic response to thyroxine replacement.
abstract: Thyroid diseases may be associated with a wide variety of dermatologic disorders. We report a 15-year-old girl with acquired ichthyosis and hypertrichosis associated with hypothyroidism resulting from autoimmune thyroiditis. Her skin lesions progressively resolved after 8 months of replacement therapy with L-thyroxine. This result supports the hypothesis that hypothyroidism in our patient can be directly related to the pathogenesis of acquired ichthyosis and hypertrichosis.
authors.affiliation: Department of Dermatology, University of Pavia, Policlinico S. Matteo-IRCCS, Pavia, Italy. vbrazzelli@libero.it
authors.forename: Valeria
authors.initials: V
authors.lastname: Brazzelli
authors.forename: Francesca
authors.initials: F
authors.lastname: Prestinari
authors.forename: Tania
authors.initials: T
authors.lastname: Barbagallo
authors.forename: Eleonora
authors.initials: E
authors.lastname: Bellani
authors.forename: Valeria
authors.initials: V
authors.lastname: Calcaterra
authors.forename: Daniella
authors.initials: D
authors.lastname: Larizza
authors.forename: Maria M
authors.initials: MM
authors.lastname: Lauriola
authors.forename: Giovanni
authors.initials: G
authors.lastname: Borroni
mesh_terms: D000293:Adolescent; D005260:Female; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D006983:Hypertrichosis / Q000188:drug therapy / Q000209:etiology*; D007037:Hypothyroidism / Q000188:drug therapy / Q000209:etiology*; D007057:Ichthyosis / Q000188:drug therapy / Q000209:etiology*; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D013974:Thyroxine / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D006728:Hormones; D013974:Thyroxine