Urologic complications in kidney transplantation.
Urologic complications in kidney transplantation have an incidence ranging from 3% to 20%, representing an important cause of organ loss. From January 2001 to September 2004, 123 renal transplantations were performed using an immunosuppressive protocol including basiliximab, mycophenolate mofetil, calcineurin inhibitors, and steroids. The surgical technique was vascular anastomoses to external iliac vessels, and ureteral anastomosis according to Lich Gregoire technique using a JJ ureteral stent. We report 5 renal complications (4.2%) and 4 extrarenal complications (3.5%), the majority of which required corrective surgery. The surgical strategy uses the clinical condition of the donor and the recipient; the anatomic anomalies of the graft, and a reduced cold ischemia time. Moreover, a reduction in acute rejection episodes and immediate renal function has been fundamental to reduce urologic complications. In fact, the main cause of urologic complications is ureteral ischemia, linked both to backtable surgery and to rejection episodes. Another important factor in the reduction of early urologic complications has been the routine use of a JJ stent, which allowed us a conservative approach in this setting.
Pisani
F
F
U.O. Trapianti, Dipartimento di Scienze Chirurgiche, Università L'Aquila, Coppito, Italy.
Iaria
G
G
D'Angelo
M
M
Rascente
M
M
Barletta
A
A
Rizza
V
V
Laurenzi
C
C
Famulari
A
A
D006084:Graft Rejection / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology / Q000379:methods; D011183:Postoperative Complications / Q000145:classification*; D012189:Retrospective Studies; D014570:Urologic Diseases / Q000453:epidemiology* / Q000209:etiology