title: Glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.
abstract: Glomerular tip lesion and its relation to different glomerular diseases is a subject of controversy. The therapeutic and prognostic clinical implications of glomerular tip lesions are ambiguous. We present a case of glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome that further complicates this issue. To our knowledge, this is the first case report of glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.
authors.affiliation: Division of Nephrology, Hypertension, and Transplantation, Department of Pathology, University of Florida, Gainesville, FL 32610-0224, USA.
authors.forename: Inderpreet
authors.initials: I
authors.lastname: Sekhon
authors.forename: Sandeep
authors.initials: S
authors.lastname: Munjal
authors.forename: Byron
authors.initials: B
authors.lastname: Croker
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Johnson
authors.forename: A Ahsan
authors.initials: AA
authors.lastname: Ejaz
mesh_terms: D000063:Accidents, Traffic; D000082:Acetaminophen / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001463:Barbiturates / Q000008:administration & dosage / Q000627:therapeutic use; D002110:Caffeine / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005487:Foam Cells / Q000648:ultrastructure*; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage / Q000627:therapeutic use*; D007678:Kidney Glomerulus / Q000473:pathology*; D009402:Nephrosis, Lipoid / Q000139:chemically induced* / Q000473:pathology; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000473:pathology; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D014147:Tramadol / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001463:Barbiturates; D000082:Acetaminophen; D014147:Tramadol; D002110:Caffeine; C004470:butalbital; D007052:Ibuprofen