title: Squamous cell carcinoma of the pancreas.
abstract: Squamous cell carcinoma of the pancreas is a rare condition. The incidence has been estimated at approximately 1% of all pancreatic malignancies. The histogenesis is uncertain, but it has been proposed to originate from areas of squamous metaplasia of pancreatic ductal epithelium. We present a case of a 56-year-old man who presented with back pain and was found to have a squamous cell carcinoma of the pancreas without evidence of metastatic disease. Three months after en bloc resection with negative margins and lymph nodes, he presented with widely metastatic disease. A review of the literature on the topic is presented, and the poor prognosis of this rare tumor, despite complete surgical resection, is discussed.
authors.affiliation: Department of Surgical Oncology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
authors.forename: Hilary A
authors.initials: HA
authors.lastname: Brown
authors.forename: Jorge
authors.initials: J
authors.lastname: Dotto
authors.forename: Marie
authors.initials: M
authors.lastname: Robert
authors.forename: Ronald R
authors.initials: RR
authors.lastname: Salem
mesh_terms: D000008:Abdominal Neoplasms / Q000556:secondary; D001416:Back Pain / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000556:secondary; D014057:Tomography, X-Ray Computed