title: [Levels of polychlorinated dibenzo-p-dioxins and dibenzo-furans in sea fish samples in some sea areas in China].
abstract: OBJECTIVE
  To analyse the levels of polychlorinated dibenzo-p-dioxins and dibenzo-furans (PCDD/Fs) in sea fish samples in some sea area in China surveyed by using isotope dilution HRGC/HRMS and was evaluated the local people with PCDD/Fs exposure from eating fish.
  
  
  METHODS
  Seven different kinds of fish and twenty fishes were sampled totally. Dibenzo-p-dioxins and dibenzo-furans were extracted from fish samples by Soxhlet extraction, concentrated and purified by FMS column chromatograph and enriched by carbon column. Confirmation and quantitative analysis at ng/kg level of PCDD/Fs was performed by HRGC/HRMS using multiple ion detection mode (MID).
  
  
  RESULTS
  Carp-2 was the certified reference material obtained from the NRC Institute of Canada. The concentration of 9 compounds was consistent with the certified value, and precision was evaluated in this study. The relative standard deviation was less than 15 percent for three times determination. The average concentration of 20 sea fishes was 1.48 ng/kg wet weight, the range was in 0.21-8.10 ng/kg wet weight, and the average total toxicity equivalency factor (TEQ) was 0.292 ng TEQ/kg (wet weight basis) and the range was 0.030-1.291 ng TEQ/kg for these 20 fishes. The evaluation exposure from fish for local people was 0.58 pg WHO-TEQ/kg BW.day.
  
  
  CONCLUSIONS
  The levels of PCDD/Fs was different from sample to sample, and the exposure from fish be less than WHO tolerance limit standard, however, the status for PCDD/Fs pollution should not be ignored especially when having an intake of multi-food.
authors.affiliation: Persistent Organic Pollution Laboratory, Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, China.
authors.forename: Jian-qing
authors.initials: JQ
authors.lastname: Zhang
authors.forename: You-sheng
authors.initials: YS
authors.lastname: Jiang
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Jiang
authors.forename: Zhi-xiong
authors.initials: ZX
authors.lastname: Zhuang
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Liu
authors.forename: Yong-ning
authors.initials: YN
authors.lastname: Wu
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000032:analysis*; D002681:China; D004147:Dioxins / Q000032:analysis*; D004785:Environmental Pollutants / Q000032:analysis*; D005399:Fishes; D011078:Polychlorinated Biphenyls / Q000032:analysis; D017747:Seafood / Q000032:analysis
chemical_list: D001572:Benzofurans; D004147:Dioxins; D004785:Environmental Pollutants; D011078:Polychlorinated Biphenyls; C020887:dibenzo(1,4)dioxin