title: Critical assessment of methods of protein structure prediction (CASP)--round 6.
abstract: This article is an introduction to the special issue of the journal Proteins, dedicated to the sixth CASP experiment to assess the state of the art in protein structure prediction. The article describes the conduct of the experiment and the categories of prediction included, and outlines the evaluation and assessment procedures. A brief summary of progress over the decade of CASP experiments is also provided.
authors.affiliation: Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland.
authors.forename: John
authors.initials: J
authors.lastname: Moult
authors.affiliation: Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Fidelis
authors.affiliation: CUBIC, Columbia University, Department of Biochemistry and Molecular Biophysics, New York, New York.
authors.forename: Burkhard
authors.initials: B
authors.lastname: Rost
authors.affiliation: Sanger Institute, Wellcome Trust Genome Campus, Cambridgeshire, United Kingdom.
authors.forename: Tim
authors.initials: T
authors.lastname: Hubbard
authors.affiliation: Istituto Pasteur-Fondazione Cenci Bolognetti, University of Rome "La Sapienza," Rome, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Tramontano
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D008958:Models, Molecular; D015233:Models, Statistical; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods*; D020539:Sequence Analysis, Protein
chemical_list: D011506:Proteins