Dystrophic xanthomatosis in primary CD30-positive cutaneous T-cell lymphoma. Report of two cases and review of the literature.
The development of xanthomatous changes in lesions of primary cutaneous T-cell lymphomas (CTCL) is a rare event. It is usually observed in regressing skin tumours or plaques spontaneously or after a specific treatment. The pathogenetic mechanisms implicated in these changes are poorly understood. We are reporting 2 cases of extensive dystrophic xanthomatous changes, developing in regressing lesions of primary cutaneous CD30-positive T-cell lymphoproliferative disorders. Previously reported cases of primary CTCL developing secondary (dystrophic) xanthomata are reviewed.
Giménez
Sonia
S
Department of Dermatology, Hospital de Bellvitge, Barcelona, Spain.
Gallardo
Fernando
F
Curcó
Neus
N
Marcoval
Joaquim
J
Romagosa
Vicenç
V
Servitje
Octavio
O
Pujol
Ramon M
RM
D000328:Adult; D000369:Aged, 80 and over; D006801:Humans; D017730:Ki-1 Antigen / Q000276:immunology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications / Q000276:immunology / Q000628:therapy*; D008297:Male; D014973:Xanthomatosis / Q000209:etiology*
D017730:Ki-1 Antigen