title: Contrast-enhanced high-resolution magnetic resonance imaging of autologous cartilage implants of the knee joint.
abstract: Over the past decade, a number of interventions for durable cartilage repair have emerged. Magnetic resonance (MR) tomography is an excellent noninvasive method for monitoring cartilage repair tissues throughout the postsurgical period. However, evaluating cartilage morphology after matrix-based autologous cartilage implantation (ACI) with MR imaging (MRI) still remains a challenge. In this study, we combined a high-resolution cartilage-sensitive fast-spin echo (FSE) sequence with intravenous application of a contrast agent for enhancing synovial fluid. Two independent musculoskeletal radiologists interpreted the pictures for the thickness, length and surface of the cartilage implants. A multivariate two-way analysis of variance with two repeated measures was performed and showed that evaluation of cartilage implant morphology was significantly improved after the application of gadodiamide on proton density FSE images. Contrast-enhanced MRI of articular cartilages is a promising technique in the postoperative follow-up of patients after ACI.
authors.affiliation: Department of Radiology, Medical University of Vienna, A-1190 Vienna, Austria.
authors.forename: Christina M
authors.initials: CM
authors.lastname: Plank
authors.forename: Klaus
authors.initials: K
authors.lastname: Kubin
authors.forename: Michael
authors.initials: M
authors.lastname: Weber
authors.forename: Stefan
authors.initials: S
authors.lastname: Marlovits
authors.forename: Siegfried
authors.initials: S
authors.lastname: Trattnig
mesh_terms: D000328:Adult; D002358:Cartilage, Articular / Q000293:injuries / Q000473:pathology* / Q000637:transplantation*; D003287:Contrast Media; D005260:Female; D050724:Fractures, Cartilage / Q000473:pathology* / Q000601:surgery*; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007718:Knee Injuries / Q000473:pathology* / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA