Triarylborane ammonia complexes as ideal precursors for arylzinc reagents in asymmetric catalysis.
[reaction: see text] The value of arylboranes as precursors for arylzinc reagents in asymmetric catalysis is demonstrated. Kinetic studies on the transmetalation reaction with zinc reagents rationalize the observed differences of three classes of arylboranes in catalytic applications. By using the stable and easily accessible triarylborane ammonia complexes, an array of chiral diarylmethanols in high yield and enantioselectivity was synthesized.
Dahmen
Stefan
S
Cynora GmbH, Kaiserstrasse 100, D-52134 Herzogenrath, Germany. dahmen@cynora.de
Lormann
Matthias
M
D001592:Benzyl Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D001880:Boranes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D001592:Benzyl Alcohols; D001880:Boranes; D009942:Organometallic Compounds; D000644:Quaternary Ammonium Compounds; D015032:Zinc