title: Neurodegeneration. Huntington's research points to possible new therapies.
authors.forename: Jean
authors.initials: J
authors.lastname: Marx
mesh_terms: D000818:Animals; D001343:Autophagy; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism; D002478:Cells, Cultured; D002986:Clinical Trials as Topic; D003342:Corpus Striatum / Q000473:pathology; D004195:Disease Models, Animal; D005786:Gene Expression Regulation; D006801:Humans; D000071058:Huntingtin Protein; D006816:Huntington Disease / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology / Q000503:physiopathology*; D051379:Mice; D008928:Mitochondria / Q000378:metabolism; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism / Q000502:physiology*; D010455:Peptides; D014157:Transcription Factors / Q000378:metabolism; D019680:Trinucleotide Repeat Expansion
chemical_list: D019208:Brain-Derived Neurotrophic Factor; C086055:HTT protein, human; C506812:Htt protein, mouse; D000071058:Huntingtin Protein; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D010455:Peptides; D014157:Transcription Factors; C097188:polyglutamine