Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation.
The authors followed up 41 consecutive patients (21 symptomatic) with internal carotid artery stenosis > or =70% and previous neck irradiation. After 28 months, 15 patients (36.6%) had died, five (12.2%) had had an ischemic stroke, and 15 (36.6%) had a new malignancy. Having a new malignancy was the only independent predictor of death. The major risk for patients with ICA stenosis > or =70% and previous neck irradiation is malignancy, not stroke.
Marcel
M
M
Department of Neurology, Lille University Hospital, Lille, France.
Leys
D
D
Mounier-Vehier
F
F
Bertheloot
D
D
Lartigau
E
E
Pruvo
J P
JP
Al-Koussa
M
M
Chevalier
D
D
Henon
H
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000706:statistics & numerical data; D016893:Carotid Stenosis / Q000401:mortality*; D015984:Causality; D015897:Comorbidity; D016894:Endarterectomy, Carotid / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000532:radiotherapy; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D016609:Neoplasms, Second Primary / Q000401:mortality*; D011446:Prospective Studies; D011878:Radiotherapy / Q000009:adverse effects*; D012307:Risk Factors; D020521:Stroke / Q000401:mortality*; D016019:Survival Analysis; D016896:Treatment Outcome