title: [Calcium channel blockers and pulse wave velocity].
abstract: Calcium channel blockers (CCB) are widely used in the treatment of hypertension. Recent studies suggest that some CCB improve clinical outcome in patients with cardiovascular diseases. Pulse wave velocity (PWV) is noted as a marker of arterial stiffness. In addition, PWV is thought to be applicable as a marker related to the severity of atherosclerosis and/or predicting future atherosclerotic cardiovascular events. Recent studies suggest that CCB improve structural damage of vascular wall. Further study is proposal to evaluate whether the improvement of structural vascular damage by CCB contribute to the improvement of the prognosis.
authors.affiliation: The Second Department of Internal Medicine, Tokyo Medical University.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Shiina
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Tomiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
mesh_terms: D050197:Atherosclerosis / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D004548:Elasticity; D006801:Humans; D011674:Pulse
chemical_list: D002121:Calcium Channel Blockers