Neuroendocrine system of the skin.
Evidence is accumulating that the skin can serve as a peripheral neuroendocrine organ. The skin neuroendocrine activities are predominantly independent of regulation from the central level (which controls classical hormone secretion) but are rather regulated by local cutaneous factors. These endocrine factors would represent an exquisite regulatory layer addressed at restricting maximally the effect of noxious agents in the skin to preserve local and consequently global homeostasis.
Slominski
Andrzej
A
Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, Memphis, 38163, USA. aslominski@utmem.edu
D001363:Awards and Prizes; D006801:Humans; D009490:Neurosecretory Systems / Q000502:physiology*; D012879:Skin Physiological Phenomena