[Clinical study on Zhuyu Tongfu serial recipe combined with acupuncture and massotherapy in treating hypertensive cerebral hemorrhage].
OBJECTIVE
To observe the clinical efficacy and mechanism of Zhuyu Tongfu (ZYTF) Serial Recipe combined with acupuncture and massotherapy in treating hypertensive cerebral hemorrhage (HCH).


METHODS
One hundred and eighteen patients with hypertensive cerebral hemorrhage, on the basis of conventional Western medicine treatment, were randomly divided into ZYTF combined with acupuncture and massotherapy group (treated group) and simple Western medicine group (control group); the clinical efficacy, neurofunction deficit scoring (NDS) alterations and hematoma absorption rate of both groups were observed, and also the plasma superoxide dismutase (SOD) activity, plasma lipid peroxidase (LPO) content, erythrocyte glutathion peroxidase (GSH-Px) activity, hematocrit (Ht) and the whole blood viscosity (Va) change were also observed.


RESULTS
In the treated group, the clinical efficacy, NDS improvement and hematoma absorption rate were superior to that of the control group; comparison between the two groups after treatment showed that plasma SOD activity and GSH-Px activity got more elevated and plasma LPO content, Ht and Va more lowered in the the treated group than those in the control group.


CONCLUSIONS
ZYTF combined with acupuncture and massotherapy has better effect, its therapeutic mechanism was possibly correlated to the elevation of plasma SOD activity, GSH-Px activity and lowering of plasma LPO content, Ht and Va.
Liu
Hua
H
The Second Hospital Affiliated to Medical College, Zhejiang University, Hangzhou 310009, China. zhangguoping@ZJ.com
Zhang
Guo-ping
GP
Song
Shui-jiang
SJ
Ding
Mei-ping
MP
Zhou
Jun-fu
JF
Bie
Xiao-dong
XD
Liu
Jian-ren
JR
Zhang
Yun
Y
Li
Zhuo-hua
ZH
Gao
Hai-feng
HF
Liu
Guang-guo
GG
Fei
Lai-ting
LT
D015670:Acupuncture Therapy / Q000379:methods*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D020299:Intracranial Hemorrhage, Hypertensive / Q000628:therapy*; D008297:Male; D008405:Massage / Q000379:methods*; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal