[Effects of surface potentials of tooth hard tissue on bone remodeling in rabbit tibiae].
OBJECTIVE
To investigate the influence of surface potentials of tooth hard tissue on bone remodeling.


METHODS
After insured the surface potentials of human extracted teeth with electrochemical methods, teeth sections and artificial hydroxyapatite were implanted into 25 rabbits' tibiae. The rabbits were sacrificed at 1, 2, 4, 6 and 8 weeks after implantation, respectively. The bone regeneration was compared between opposite two sides (cathode side and anode side) of tooth sections using hematoxylin-eosin (HE) staining, tartrate-resistant acid phosphatase (TRAP) activity detecting and tetracycline tracing method.


RESULTS
Resorption lacunae was seen in the tibiae facing to the enamel anode and new bone density in the implant bed near the cathode of tooth samples was much higher than that near the anode, while the number of TRAP positive cells near the cathode was smaller than that near the anode (P < 0.01). The fluorescent area of tetracycline tracing near the cathode was larger than that near the anode (P < 0.05).


CONCLUSIONS
The cathode of tooth hard tissue (cementum) could improve or trigger new bone formation, while the other side, anode (enamel), could improve the bone resorption. This study suggests that tooth hard tissue's electrochemical characteristic might affect the remodeling of alveolar bone, and tooth supraeruption and the alveolar bone loss after tooth extraction might result from the redundant or lack of root electrochemical stimulation to bone.
Zhang
Jia-li
JL
Department of Stomatology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Zheng
You-yang
YY
Hu
Ji-an
JA
Chen
Xue-peng
XP
D016301:Alveolar Bone Loss / Q000503:physiopathology; D000818:Animals; D016723:Bone Remodeling; D003739:Dental Cementum / Q000502:physiology*; D003743:Dental Enamel / Q000502:physiology*; D003804:Dentin / Q000502:physiology; D004563:Electrochemistry; D005260:Female; D006801:Humans; D008297:Male; D011817:Rabbits; D013977:Tibia / Q000502:physiology*