title: beta-cyclodextrin-immobilized (4S)-phenoxy-(S)-proline as a catalyst for direct asymmetric aldol reactions.
abstract: beta-Cyclodextrin-immobilized (4S)-phenoxy-(S)-proline was prepared conveniently by simply heating the amino acid and beta-cyclodextrin in ethanol-water (1/1, v/v) and removal of the solvent. This proved to be an efficient catalyst for direct asymmetric aldol reactions, and the catalyst could be recycled four times without loss of enantioselectivity.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou, China.
authors.forename: Zongxuan
authors.initials: Z
authors.lastname: Shen
authors.forename: Jimei
authors.initials: J
authors.lastname: Ma
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Liu
authors.forename: Chongjun
authors.initials: C
authors.lastname: Jiao
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Yawen
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013057:Spectrum Analysis; D013237:Stereoisomerism; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: C507396:4-phenoxyproline; D000447:Aldehydes; D012997:Solvents; D047392:beta-Cyclodextrins; C116609:3-hydroxybutanal; D011392:Proline