HLA-A*2626, a new allele identified through external proficiency-testing exercise.
A new allele, officially named HLA-A*2626, has been detected in a blood sample belonging to a Caucasian subject human leucocyte antigen typed for Lombardy Region external proficiency-testing exercise. The DNA sequences of exons 2, 3 and 4 of this new allele are identical to those of HLA-A*2601 except at codon 259 of exon 4 (CCT-->CTT). This variation modifies the encoded protein from proline to leucine.
Longhi
E
E
Dipartimento Trasfusionale e di Riferimento per i Trapianti di Organi e Tessuti, Fondazione IRCCS di natura pubblica, Milan, Italy.
Frison
S
S
Colombini
I
I
Malagoli
A
A
Crespiatico
L
L
Poli
F
F
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics* / Q000276:immunology; D001483:Base Sequence; D005091:Exons / Q000235:genetics* / Q000276:immunology; D005260:Female; D015234:HLA-A Antigens / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D017354:Point Mutation / Q000235:genetics* / Q000276:immunology
D015234:HLA-A Antigens; C506274:HLA-A*26:26 antigen