Forensic informativity of domestic dog mtDNA control region sequences.
We have analysed the genetic information to be obtained from analysis of mitochondrial DNA (mtDNA) in domestic dogs studying the exclusion capacity in different populations and the correlation between mtDNA types and breeds or types of dogs. The exclusion capacities for a 573 bp sequence of the mitochondrial control region was between 0.86 and 0.95 for dogs in Sweden, the UK, Germany, Japan and China. The direct correlation between mtDNA type and breed, type of dog, and geographical origin of breed was generally low, but in some cases certain mtDNA types were overrepresented in one breed, and for wider groupings such as morphologically similar breeds, some mtDNA types were in many cases found in a distinct group of breeds, often originating from the same geographic region. This type of information may be used as an indication of the breed and, with some degree of probability, to include or exclude certain breeds from being the source of evidence materials.
Angleby
Helen
H
Department of Biotechnology, Division of Molecular Biotechnology, Royal Institute of Technology, Stockholm, Sweden.
Savolainen
Peter
P
D000818:Animals; D001947:Breeding; D016172:DNA Fingerprinting; D004272:DNA, Mitochondrial / Q000032:analysis*; D004285:Dogs / Q000235:genetics*; D005843:Geography; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013045:Species Specificity
D004272:DNA, Mitochondrial