title: Challenges in implementing a successful newborn cystic fibrosis screening program.
abstract: OBJECTIVE
  To identify necessary components of a successful cystic fibrosis (CF) newborn screening (NBS) program.
  
  
  METHODS
  The approach to CF NBS used by the Massachusetts NBS program was examined.
  
  
  RESULTS
  Several key components were identified that should be addressed when a state has made the decision to screen, and well in advance of actual implementation. These components include (1) inclusion of CF center directors in the development process; (2) logistics of choosing a screening algorithm relative to practices in place and community wishes; (3) projections of medical service needs from specific algorithms; (4) identification of critical reporting components; (5) identification of critical follow-up components; and (6) recognition of educational needs.
  
  
  CONCLUSIONS
  Careful examination of a wide variety of issues is needed to ensure optimal implementation of NBS for CF.
authors.affiliation: New England Newborn Screening Program of the University of Massachusetts Medical School, MA 02130, USA. anne.comeau@umassmed.edu
authors.forename: Anne Marie
authors.initials: AM
authors.lastname: Comeau
authors.forename: Richard
authors.initials: R
authors.lastname: Parad
authors.forename: Robert
authors.initials: R
authors.lastname: Gerstle
authors.forename: Brian P
authors.initials: BP
authors.lastname: O'Sullivan
authors.forename: Henry L
authors.initials: HL
authors.lastname: Dorkin
authors.forename: Mark
authors.initials: M
authors.lastname: Dovey
authors.forename: Kenan
authors.initials: K
authors.lastname: Haver
authors.forename: Tom
authors.initials: T
authors.lastname: Martin
authors.forename: Roger B
authors.initials: RB
authors.lastname: Eaton
mesh_terms: D000359:Aftercare / Q000458:organization & administration; D000465:Algorithms; D001291:Attitude of Health Personnel; D001294:Attitude to Health; D003550:Cystic Fibrosis / Q000175:diagnosis*; D003659:Decision Making, Organizational; D005817:Genetic Counseling / Q000458:organization & administration; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007231:Infant, Newborn; D008404:Massachusetts; D017146:Models, Organizational; D020380:Needs Assessment / Q000458:organization & administration*; D015997:Neonatal Screening / Q000458:organization & administration* / Q000523:psychology; D017063:Outcome Assessment, Health Care / Q000458:organization & administration; D010290:Parents / Q000193:education / Q000523:psychology; D008486:Physician Executives / Q000193:education / Q000458:organization & administration; D011320:Primary Health Care / Q000458:organization & administration; D016730:Program Development / Q000379:methods*; D015397:Program Evaluation / Q000379:methods; D012680:Sensitivity and Specificity; D012944:Social Support