Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone.
Although cadherins and catenins are known to play important roles during neural development, the types of alpha-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express alphaE-catenin and alphaN-catenin, respectively, in a complementary manner. In the cortex, alpha-catenin is switched from alphaE-catenin in the VZ to alphaN-catenin II in the intermediate zone (IMZ).
Ajioka
Itsuki
I
Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Nakajima
Kazunori
K
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology* / Q000378:metabolism*; D002831:Choroid Plexus / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D007150:Immunohistochemistry; D007395:Interneurons / Q000166:cytology / Q000378:metabolism; D020547:Lateral Ventricles / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D051379:Mice; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009433:Neural Inhibition / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism*; D051178:alpha Catenin / Q000378:metabolism*
C486820:Ctnna2 protein, mouse; D009419:Nerve Tissue Proteins; D051178:alpha Catenin