title: [Use of blood products in patients treated surgically for stage I non-small cell lung cancer].
abstract: OBJECTIVE
  Retrospective study on the relation between the use of blood products and survival rates in patients treated surgically for stage I non-small cell lung cancer (NSCLC).
  
  
  METHODS
  The study included 856 patients who underwent surgical resection from 1969 to 2000 for stage I NSCLC, classified histologically according to the current guidelines of the Spanish Society of Pulmonary and Thoracic Surgery (SEPAR). Patients who died in the postoperative period were excluded from the study. A series of clinicopathological variables were recorded, including the perioperative use or not of blood products. Descriptive, univariate, and multivariate statistical analyses were performed. Follow up concluded in December of 2003.
  
  
  RESULTS
  One hundred twenty-five patients (14.6%) underwent a perioperative transfusion. A significant association was found between the use of blood products and tumor size (P<.001), pneumectomy (P<.001), and cell type (P<.05). The respective 2, 5, and 10-year survival rates were 78%, 63%, and 54% for the nontransfusion group, and 73%, 59%, and 46% for the transfusion group. Both survival curves were compared and no significant differences were found (P=.23). Multivariate regression analysis included tumor size, patient age, and histologic cell type (squamous cell carcinoma or not); no relation between transfusion and survival was found.
  
  
  CONCLUSIONS
  In our series, we found no difference in survival rates for patients with stage I NSCLC after perioperative blood transfusion.
authors.affiliation: Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, Spain. jpenalve@ono.com
authors.forename: J C
authors.initials: JC
authors.lastname: Peñalver
authors.forename: J
authors.initials: J
authors.lastname: Padilla
authors.forename: C
authors.initials: C
authors.lastname: Jordá
authors.forename: J
authors.initials: J
authors.lastname: Escrivá
authors.forename: J
authors.initials: J
authors.lastname: Cerón
authors.forename: V
authors.initials: V
authors.lastname: Calvo
authors.forename: A
authors.initials: A
authors.lastname: García
authors.forename: J
authors.initials: J
authors.lastname: Pastor
authors.forename: E
authors.initials: E
authors.lastname: Blasco
mesh_terms: D000368:Aged; D001803:Blood Transfusion; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D012189:Retrospective Studies; D016019:Survival Analysis