title: Comparison of five MR sequences for the detection of acute intracranial hemorrhage.
abstract: OBJECTIVE
  To evaluate the respective value of 5 MR sequences to distinguish between stroke patients with and without acute intracerebral hemorrhage (ICH).
  
  
  METHODS
  MR images obtained < or =6 h after stroke onset of 86 patients (43 ICH, 43 non-ICH) were reviewed by 3 observers who looked for signs of acute ICH on each image set [T(1) and T(2) gradient echo (GRE), FLAIR, T(2)-EPI and DWI], presented separately.
  
  
  RESULTS
  For the identification of ICH, intraobserver and interobserver concordance were at least kappa = 0.95 for all sequences. Of all interpretations, 7 (0.4%) were erroneous, with sensitivity and specificity of FLAIR, T(2)-EPI and DWI reaching 100%; GRE sensitivity and specificity were 100% and 95-97.5%, respectively; T(1) sensitivity and specificity were 97.3-100% and 97.4-100%, respectively. All 4 patients misclassified on one pulse sequence were correctly classified on all the other sequences.
  
  
  CONCLUSIONS
  In the setting of acute stroke, each of the 5 studied sequences enables ICH and non-ICH patients to be distinguished with high sensitivity and specificity.
authors.affiliation: Department of Neuroradiology, Sainte-Anne Hospital, Paris V University, France. e.oppenheim@ch-sainte-anne.fr
authors.forename: Catherine
authors.initials: C
authors.lastname: Oppenheim
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Touzé
authors.forename: Danielle
authors.initials: D
authors.lastname: Hernalsteen
authors.forename: André
authors.initials: A
authors.lastname: Peeters
authors.forename: Catherine
authors.initials: C
authors.lastname: Lamy
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Mas
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Meder
authors.forename: Guy
authors.initials: G
authors.lastname: Cosnard
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D020521:Stroke / Q000473:pathology*