title: [Insulin-like growth factor and interacting proteins].
abstract: Insulin-like growth factor - IGF-I is a small, 70 aminoacid mitogenic peptide, contributing to processes of growing, cancerogenesis, apoptosis, wound healing and many others. It constitutes so called 'somatotropic axis GH-IGF', composed of many other components. This axis is responsible for regulation of metabolic processes, and its proper functioning conditions organism's homeostasis. Presented work describes concise review of publications concerning IGF-I structure, function, expression and proteins affecting its activity, synthesis and circulation.
authors.affiliation: Interdepartmental Laboratory of Molecular Biology, Plant Protection Institute, 20 Miczurina St., 60-318 Poznan, Poland. ao.steplowska@ior.poznan.pl
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Obrepalska-Steplowska
authors.forename: Lukasz
authors.initials: L
authors.lastname: Durzyński
authors.forename: Anna
authors.initials: A
authors.lastname: Goździcka-Józefiak
mesh_terms: D015870:Gene Expression; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*
chemical_list: D007334:Insulin-Like Growth Factor I