title: Novel synthesis of 2-aryl and 2,3-disubstituted indoles by modified double elimination protocol.
abstract: [reaction: see text] Syntheses of 2-aryl and 2,3-substituted indoles were realized by modified double elimination protocol. Under basic conditions, vinyl sulfones derived from the reaction of 2-aminobenzyl sulfone with benzaldehydes underwent cyclization and alkylation followed by elimination of sulfinic acid to afford 2,3-substituted indoles.
authors.affiliation: Department of Applied Chemistry, Okayama University of Science, Ridai-cho, Okayama 700-0005, Japan.
authors.forename: Govindarajulu
authors.initials: G
authors.lastname: Babu
authors.forename: Akihiro
authors.initials: A
authors.lastname: Orita
authors.forename: Junzo
authors.initials: J
authors.lastname: Otera
mesh_terms: D000478:Alkylation; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013450:Sulfones / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D007211:Indoles; D013450:Sulfones; C009873:divinyl sulfone