[Cryosurgical ablation for 23 cases of prostate cancer guided by rectal ultrasound].
OBJECTIVE
To detect the short-term clinical and side effects of cryosurgical ablation for prostate cancer.


METHODS
The ENDOCAm cryosurgical system with 2 mm Cryo-probes was used to treat the prostate cancer guided by rectal ultrasonic. 1. Completeness of freeze; 2. Complications; 3. The changes of PSA and PSMA before and after operation were observed respectively.


RESULTS
1. The completeness of freeze rate and non-completeness of freeze rate were 34.8% (8/23) and 65.2% (15/23) showed by MRI 3 weeks later after operation; the biopsy results showed that tumor positive rates in completeness of freeze group and non-completeness of freeze group were 0 and 20% (3/15) respectively after 6 months. 2. The incontinence rate was 13%, and all recovered during 1 month; and the erectile dysfunction rate post-operation was 56.2% (9/16). 3. The levels of PSA before and after cryosurgical ablation were (32.98 +/- 35. 50) microg/L, (11.65 +/- 26. 51) microg/L respectively (P < 0.05). PSMA increased significantly after the cryosurgical ablation.


CONCLUSIONS
The short-term curative effects of cryosurgical ablation, which guided by rectal ultrasound for prostate cancer is satisfied with low complication rate and minor vulnus.
Wu
Qing
Q
Department of Clinical Oncology, the Affiliated Changzheng Hospital of Second Military Medicine University of PLA, Shanghai. wuching@163.com
Wang
Xue-song
XS
Qian
Jian-xin
JX
Zhang
Jia-xing
JX
Xu
Qing
Q
Cao
Chuan-wu
CW
Gu
Xiao-qiang
XQ
Luo
Yi-zhou
YZ
Wang
Jie-jun
JJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003452:Cryosurgery / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*; D012007:Rectum / Q000000981:diagnostic imaging; D014463:Ultrasonography
D017430:Prostate-Specific Antigen