title: Stem cell regulation in the Arabidopsis shoot apical meristem.
abstract: The aerial structure of higher plants is generated dynamically throughout the life cycle through the activity of stem cells that are located at the growing shoot tip, the apical meristem. The stem cells continuously divide to renew themselves and provide cells for leaf, stem and flower formation. Stem cell maintenance is governed by intercellular communication between the apical stem cells and the underlying organizing centre. Recent advances have been made in understanding the mechanisms that induce shoot stem cell identity, and that control the position and size of the organizing centre. Elements such as chromatin remodeling factors, transcription factors and microRNAs are newly implicated in these regulatory processes. These advances provide a framework for our understanding of how signals are integrated to specify and position the stem cell niche in the shoot apical meristem.
authors.affiliation: USDA-ARS Plant Gene Expression Center, 800 Buchanan Street, Albany, California 94710, and Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, California 94720, USA.
authors.forename: Leor
authors.initials: L
authors.lastname: Williams
authors.forename: Jennifer C
authors.initials: JC
authors.lastname: Fletcher
mesh_terms: D017360:Arabidopsis / Q000166:cytology* / Q000235:genetics / Q000254:growth & development*; D002843:Chromatin / Q000235:genetics / Q000378:metabolism; D018506:Gene Expression Regulation, Plant / Q000235:genetics; D018520:Plant Shoots / Q000166:cytology* / Q000235:genetics / Q000254:growth & development*; D013234:Stem Cells / Q000502:physiology*
chemical_list: D002843:Chromatin