[A study of physicochemical properties of 2-, 3-, 4-alkoxyphenylcarbamic acid derivatives with a substituted N-phenylpiperazine moiety in the basic part].
The paper presents the study of some physicochemical properties of 2-, 3-, 4-alkoxyphenylcarbamic acid derivatives with various substituted N-phenylpiperazin-1-yl moiety in the basic part of the molecule. Elemental analysis, melting point, solubility, surface activity, dissociation constant and some lipophilicity parameters i.e.--partition coefficient, capacity factor obtained from HPLC, and R(M) values from reversed-phase thin-layer chromatography were determined.
Malík
I
I
Farmaceutická fakulta Univerzity Komenského v Bratislave, Katedra farmaceutickej chémie, SR. malik@fpharm.uniba.sk
Sedlárová
E
E
Cizmárik
J
J
Andriamainty
F
F
Csöllei
J
J
D055598:Chemical Phenomena; D002626:Chemistry, Pharmaceutical; D002627:Chemistry, Physical; D048448:Phenylcarbamates / Q000737:chemistry*; D010879:Piperazines / Q000737:chemistry*
D048448:Phenylcarbamates; D010879:Piperazines; C031503:phenylpiperazine