title: The effect of bio-converted polyunsaturated fatty acids on the oxidation of TAG containing highly unsaturated fatty acids.
abstract: Microbial modification of vegetable fatty acids can often lead to special changes in their structure and in biological function. A bacterial strain, Pseudomonas aeruginosa PR3, is known to carry out multiple hydroxylations on polyunsaturated fatty acids containing 1,4-cis, cis diene structural units, resulting in antibacterial activity. In this paper, in an effort to understand the overall mechanism involved in the varied biological functions of the complicated metabolites of bio-converted polyunsaturated fatty acids, we performed bioconversion of several polyunsaturated fatty acids using PR3, and determined their oxidative activities against fish oil. Bio-converted linoleic acid, eicosapentanoic acid, and docosahexanoic acid promoted effectively oxidation of fish oil. It is assumed that this oxidative effect could plausibly play an important role in the antimicrobial function of these bio-converted fatty acids.
authors.affiliation: Department of Animal Science and Biotechnology, Kyungpook National University, Daegu, 702-701, Korea.
authors.forename: Young-Mi
authors.initials: YM
authors.lastname: Kim
authors.forename: Geon-Ho
authors.initials: GH
authors.lastname: Lee
authors.forename: Young-Geun
authors.initials: YG
authors.lastname: Yeo
authors.forename: In-Hwan
authors.initials: IH
authors.lastname: Kim
authors.forename: Kazuo
authors.initials: K
authors.lastname: Miyashita
authors.forename: Ching T
authors.initials: CT
authors.lastname: Hou
authors.forename: Sun-Chul
authors.initials: SC
authors.lastname: Kang
authors.forename: Hak-Ryul
authors.initials: HR
authors.lastname: Kim
mesh_terms: D005231:Fatty Acids, Unsaturated / Q000032:analysis / Q000378:metabolism*; D005395:Fish Oils / Q000494:pharmacology*; D010084:Oxidation-Reduction; D011550:Pseudomonas aeruginosa / Q000378:metabolism*
chemical_list: D005231:Fatty Acids, Unsaturated; D005395:Fish Oils