title: [Recurrent signet-ring cell gastric carcinoma evidenced by FDG-PET].
abstract: OBJECTIVE
  To present the case report of a patient with undifferentiated and diffuse signet-ring cell gastric carcinoma in which FDG-PET evidenced recurrent disease.
  
  
  METHODS
  The patient was diagnosed of a stage III gastric carcinoma in 1994 and was treated with a subtotal gastrectomy. In February 2003, recurrent disease was detected in mediastinal and left supraclavicular lymph nodes. The patient was treated with chemotherapy and radiotherapy, reaching a complete response. After 6 months free of disease, he presented an elevation of the tumor markers with negative results in conventional imaging methods (upper digestive endoscopy, bone scintigraphy, and CT). An FDG-PET scan was performed to rule out recurrent disease.
  
  
  RESULTS
  FDG-PET detected pathologic findings suggestive of malignant disease in right supraclavicular and mediastinal lymph nodes. These findings were confirmed by clinical follow-up and with another CT scan performed 4 months later.
  
  
  CONCLUSIONS
  In this case report we stress the importance of early recurrence by FDG-PET in a non-intestinal gastric carcinoma. This is of interest given the greater difficulty to detect mucous secreting and/or producing carcinomas with the PET-FDG.
authors.affiliation: Instituto PET FOCUSCAN S.L., Madrid.
authors.forename: G
authors.initials: G
authors.lastname: Ruiz-Hernández
authors.forename: R C
authors.initials: RC
authors.lastname: Delgado-Bolton
authors.forename: M J
authors.initials: MJ
authors.lastname: Rubio-Pérez
authors.forename: A
authors.initials: A
authors.lastname: Jiménez-Vicioso
authors.forename: M J
authors.initials: MJ
authors.lastname: Pérez-Castejón
authors.forename: J L
authors.initials: JL
authors.lastname: Carreras-Delgado
mesh_terms: D000368:Aged; D018279:Carcinoma, Signet Ring Cell / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18