title: Structural organization of the transfer RNA operon I of Vibrio cholerae: differences between classical and El Tor strains.
abstract: Nine major transfer RNA (tRNA) gene clusters were analysed in various Vibrio cholerae strains. Of these, only the tRNA operon I was found to differ significantly in V. cholerae classical (sixth pandemic) and El Tor (seventh pandemic) strains. Amongst the sixteen tRNA genes contained in this operon, genes for tRNA Gln3 (CAA) and tRNA Leu6 (CUA) were absent in classical strains as compared to El Tor strains. The observation strongly supported the view that the above two pandemic strains constitute two different clones.
authors.affiliation: Molecular Biology Laboratory, Indian Institute of Chemical Biology, 4, Raja SC Mullick Road,Jadavpur, Kolkata 700 032, India.
authors.forename: Atreyi
authors.initials: A
authors.lastname: Ghatak
authors.forename: Anasuya
authors.initials: A
authors.lastname: Majumdar
authors.forename: Ranajit K
authors.initials: RK
authors.lastname: Ghosh
mesh_terms: D009876:Operon / Q000235:genetics*; D012343:RNA, Transfer / Q000737:chemistry* / Q000235:genetics; D014734:Vibrio cholerae / Q000145:classification / Q000235:genetics*; D012407:rRNA Operon / Q000235:genetics
chemical_list: D012343:RNA, Transfer