title: Nutritional intervention with omega-3 Fatty acids in a case of malignant fibrous histiocytoma of the lungs.
abstract: We present a case of a 78-yr-old man with malignant fibrous histiocytoma with multiple lesions in both lungs. Following diagnosis, he declined conventional chemotherapy and elected nutritional intervention by increasing intake of omega-3 fatty acids and lowering intake of omega-6 fatty acids. We estimated that he consumed 15 g of the long-chain omega-3 fatty acids eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) per day, and the ratio of linoleic acid/long-chain omega-3 fatty acids in his diet was 0.81. Serial computed tomography scans and pulmonary x-rays revealed remarkably a slow and steady decrease in the size and number of bilateral nodules. He has no apparent side effects from consuming large quantities of fish and algae oils rich in DHA and EPA and he remains asymptomatic.
authors.affiliation: Department of Biochemistry, College of Agriculture, Biotechnology and Natural Resources, University of Navada, Reno, NV 89557, USA. ronp@cabnr.unr.edu
authors.forename: Ronald S
authors.initials: RS
authors.lastname: Pardini
authors.forename: David
authors.initials: D
authors.lastname: Wilson
authors.forename: Steven
authors.initials: S
authors.lastname: Schiff
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Bajo
authors.forename: Randall
authors.initials: R
authors.lastname: Pierce
mesh_terms: D000368:Aged; D018450:Disease Progression; D004281:Docosahexaenoic Acids / Q000627:therapeutic use; D015118:Eicosapentaenoic Acid / Q000627:therapeutic use; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D005395:Fish Oils; D051677:Histiocytoma, Malignant Fibrous / Q000178:diet therapy* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000178:diet therapy* / Q000473:pathology; D008297:Male
chemical_list: D015525:Fatty Acids, Omega-3; D005395:Fish Oils; D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid