title: Aplasia cutis congenita of the scalp: how much therapy is necessary in large defects?
abstract: OBJECTIVE
  To show that local antibiotic management and a regular inspection of aplasia cutis congenita of the skull can give an excellent result.
  
  
  METHODS
  This case reports a girl born with aplasia cutis congenita of the skull presenting with a large aplasia of the epidermis, dermis, subcutaneous tissue and galea, including a bone defect without any additional risk factor, e.g. early eschar formation, cerebrospinal fluid leakage or uncommon dural blood vessels.
  
  
  RESULTS
  A primarily conservative treatment with local wet and antibiotic dressings together with a systemic antibiotic treatment for the first 2 wk led to an excellent result and thus prevented untimely operative and peri-operative procedures.
  
  
  CONCLUSIONS
  Here we have shown that conservative treatment might be an option, even if the wound diameter is greater than 1 cm(2), to prevent infants from any untimely operative procedure with an elevated operative risk if any additional risk factors are excluded.
authors.affiliation: Children's Hospital, Heinrich Heine University Medical Centre, Düsseldorf, Germany. Bernbeck@med.uni-duesseldorf.de
authors.forename: B
authors.initials: B
authors.lastname: Bernbeck
authors.forename: J
authors.initials: J
authors.lastname: Schwabe
authors.forename: A
authors.initials: A
authors.lastname: Groninger
authors.forename: J
authors.initials: J
authors.lastname: Schaper
authors.forename: H
authors.initials: H
authors.lastname: Messing-Jünger
authors.forename: E
authors.initials: E
authors.lastname: Mayatepek
authors.forename: T
authors.initials: T
authors.lastname: Rosenbaum
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D004476:Ectodermal Dysplasia / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012536:Scalp Dermatoses / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents