title: Case report: Malignant peripheral nerve sheath tumor of the uterine cervix treated with radical vaginal trachelectomy.
abstract: BACKGROUND
  Malignant peripheral nerve sheath tumors (MPNST) are rare tumors which occur primarily in major nerve trunks and most commonly in patients with neurofibromatosis. Only seven prior cases of these tumors arising in the uterine cervix have been reported, all of which were treated by hysterectomy.
  
  
  METHODS
  We report a 22-year-old woman with MPNST of the uterine cervix which recurred after loop electrocautery excision and had positive margins on cone biopsy. She was treated definitively with radical trachelectomy and is well with no sign of recurrence 20 months later.
  
  
  CONCLUSIONS
  MPNST of the uterine cervix is a rare, but potentially aggressive neoplasm. This is the first case of such a tumor treated successfully with preservation of the patients fertility.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of California, Davis Medical Center, 4860 Y Street, Suite 2500, Sacramento, CA 95817, USA. anne.rodriguez@ucdmc.ucdavis.edu
authors.forename: Anne O
authors.initials: AO
authors.lastname: Rodriguez
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Truskinovsky
authors.forename: Monica
authors.initials: M
authors.lastname: Kasrazadeh
authors.forename: Gary S
authors.initials: GS
authors.lastname: Leiserowitz
mesh_terms: D000328:Adult; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D018317:Nerve Sheath Neoplasms / Q000473:pathology / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*