Chemotactic collapse and mesenchymal morphogenesis.
We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal morphogenesis represents thus a more complex type of pattern formation than those found in bacterial colonies. We compare our theoretical predictions with recent in vitro experiments.
Escudero
Carlos
C
Departamento de Física Fundamental, Universidad Nacional de Educación a Distancia, C/Senda del Rey 9, 28040 Madrid, Spain.
D000818:Animals; D002449:Cell Aggregation / Q000502:physiology*; D002478:Cells, Cultured; D002633:Chemotaxis / Q000502:physiology*; D003198:Computer Simulation; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology*; D008954:Models, Biological; D009024:Morphogenesis / Q000502:physiology*