title: [Unspecified gain of weight?].
abstract: In the case of a 49 year old patient, a weight gain of 37 kg occurred during the first weeks of the year 2003, accompanied by a painless increase in the diameter of the upper arms and thighs. This process did spontaneously cease in the summer of 2003, but weight reduction could not be achieved. The diagnosis of multiple symmetrical lipomatosis, also known as Launois-Bensaude syndrome, the first authors to describe the condition in detail in 1898, could be established due to the unique appearance of the patient. Typical features of the disease are the accumulation of multiple lipomata in the shoulder girdle, upper arms, thorax and thighs, whereas the face, the forearms and the shanks are typically excluded. The etiology of the disease is obscure, dietetic intervention is futile, surgical approaches are liposuction or excision of the lipomata. Cessation of alcohol consumption may also be helpful, since the condition is typically associated with present or past alcohol abuse. The disease is usually reported to be rare, but there is reason enough to assume, that it is frequently misdiagnosed as simple truncal obesity.
authors.affiliation: Abteilung Endokrinologie und Stoffwechsel, Medizinische Klinik I der Friedrich-Alexander-Universität Erlangen-Nürnberg. Igor.harsch@med1.imed.uni-erlangen.de
authors.forename: I A
authors.initials: IA
authors.lastname: Harsch
authors.forename: R
authors.initials: R
authors.lastname: Wiedmann
authors.forename: T
authors.initials: T
authors.lastname: Bergmann
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
authors.forename: G H
authors.initials: GH
authors.lastname: Wiest
mesh_terms: D003937:Diagnosis, Differential; D004035:Diet Therapy; D006801:Humans; D015187:Lipectomy; D008069:Lipomatosis, Multiple Symmetrical / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000175:diagnosis* / Q000628:therapy*; D013577:Syndrome; D017211:Treatment Failure; D015430:Weight Gain