Seeing in color--warts and all.
In the September 9th issue of Cell, Mikeladze-Dvali et al. show that cell fate decisions needed for color vision are dependent on a bistable negative feedback loop between genes previously implicated in cell proliferation (warts) and growth (melted).
Bateman
Joseph M
JM
Samuel Lunenfeld Research Institute, Toronto, Canada.
McNeill
Helen
H
D000818:Animals; D019070:Cell Lineage; D003116:Color; D003118:Color Perception / Q000502:physiology*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000033:anatomy & histology* / Q000502:physiology; D025461:Feedback, Physiological; D017956:Photoreceptor Cells, Invertebrate / Q000166:cytology / Q000502:physiology; D020033:Protein Isoforms / Q000737:chemistry / Q000378:metabolism; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D012243:Rhodopsin / Q000737:chemistry / Q000378:metabolism
D029721:Drosophila Proteins; D020033:Protein Isoforms; D012243:Rhodopsin; D011494:Protein Kinases; C093503:wts protein, Drosophila