Local protection for surgical implants.
In this issue of Chemistry & Biology, Jose and coworkers [1] describe the covalent attachment of vancomycin to a titanium surface. The tethered antibiotic is effective against S. aureus, suggesting that this material has the potential to complement clinical strategies for preventing infection following implant surgery.
Lucke
Martin
M
Center for Musculoskeletal Surgery, Charité-University Medicine Berlin, Germany.
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001422:Bacterial Adhesion / Q000187:drug effects; D019736:Prostheses and Implants; D013211:Staphylococcus aureus / Q000187:drug effects; D014025:Titanium / Q000737:chemistry*; D014640:Vancomycin / Q000737:chemistry* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D014025:Titanium