title: Variability of vascularity in nasal mucosa as demonstrated by CD34 immunohistochemistry.
abstract: Regional anatomical variations in the nasal vasculature have not been studied histologically. Immunohistochemistry performed using marker for CD34 antigen on vascular endothelium biopsied from 5 sites on the lateral nasal wall and compared with one septal biopsy. No significant regional variations in microvascular architecture over the lateral wall of the nose were found. * Lateral wall measurements were significantly different to the septal measurements (P = 0.0003, 0.01). Suggests biopsies can be taken from any site on the lateral wall and give a representative sampling of the vascularity for research purposes.
authors.affiliation: Department of Otorhinolaryngology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, UK. carlphilpott@btopenworld.com
authors.forename: C M
authors.initials: CM
authors.lastname: Philpott
authors.forename: D
authors.initials: D
authors.lastname: Wild
authors.forename: M
authors.initials: M
authors.lastname: Guzail
authors.forename: G E
authors.initials: GE
authors.lastname: Murty
mesh_terms: D000704:Analysis of Variance; D018952:Antigens, CD34 / Q000032:analysis* / Q000276:immunology; D044963:Biopsy, Fine-Needle; D006801:Humans; D007150:Immunohistochemistry; D008833:Microcirculation / Q000033:anatomy & histology; D009297:Nasal Mucosa / Q000033:anatomy & histology / Q000098:blood supply*; D009300:Nasal Septum / Q000098:blood supply; D015203:Reproducibility of Results; D014420:Turbinates / Q000098:blood supply
chemical_list: D018952:Antigens, CD34