[Calciphylaxis in terminal renal failure as a rare manifestation of leg ulcers].
Calciphylaxis is a potentially life-threatening disease that occurs up to 4% of patients with chronic terminal renal failure and secondary hyperparathyroidism. Clinical symptoms are painful skin erythema and ischemic necrosis as a result of calcification of the small and medium-sized arteries of the subcutaneous tissues. The mortality of the disease is as high as 87% mainly due to sepsis from superinfection. We report on a 59-year-old patient with chronic renal failure and normal calcium-phosphate-product with leg ulcers as a rare manifestation of a calciphylaxis. In spite of an early parathyroidectomy and a temporary complete wound-healing the death because of calciphylaxis could not be prevented.
Klode
J
J
Dermatologische Abteilung, Katharinen-Hospital, Unna. joachimklode@yahoo.de
Winzer
M
M
Böhmer
H J
HJ
Heisterkamp
Th
T
Dissemond
J
J
D002115:Calciphylaxis / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D007871:Leg Ulcer / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D035583:Rare Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery