Chemical composition and anti-inflammatory activity of the volatile fractions from the bark of eight Mexican Bursera species.
The volatile fractions from the bark of eight species of Mexican Bursera were obtained using steam distillation and were subjected to tandem GC-MS analysis for identification of the main constituents. The most abundant components of steam volatiles were monoterpenoids from which alpha-terpineol, terpinen-4-ol, alpha-thujene, linalool and limonene were most frequently isolated. A series of sesquiterpenes and long-chain hydrocarbons were isolated and identified from the barks of some of the studied species . Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice. The volatile fraction from Bursera lancifolia was about half as active as indomethacin.
Zúñiga
Beatriz
B
Laboratorio de Química, Facultad de Ciencias, Universidad Nacional Autónoma de México, México.
Guevara-Fefer
Patricia
P
Herrera
Josefina
J
Contreras
José Luis
JL
Velasco
Luis
L
Pérez
Francisco Javier
FJ
Esquivel
Baldomero
B
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D031233:Bursera; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control*; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male; D008519:Medicine, Traditional; D008800:Mexico; D051379:Mice; D008815:Mice, Inbred Strains; D039821:Monoterpenes / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D009822:Oils, Volatile / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D008517:Phytotherapy; D024301:Plant Bark; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D013755:Tetradecanoylphorbol Acetate
D000894:Anti-Inflammatory Agents, Non-Steroidal; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils; D013755:Tetradecanoylphorbol Acetate