title: Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation.
abstract: The authors followed up 41 consecutive patients (21 symptomatic) with internal carotid artery stenosis > or =70% and previous neck irradiation. After 28 months, 15 patients (36.6%) had died, five (12.2%) had had an ischemic stroke, and 15 (36.6%) had a new malignancy. Having a new malignancy was the only independent predictor of death. The major risk for patients with ICA stenosis > or =70% and previous neck irradiation is malignancy, not stroke.
authors.affiliation: Department of Neurology, Lille University Hospital, Lille, France.
authors.forename: M
authors.initials: M
authors.lastname: Marcel
authors.forename: D
authors.initials: D
authors.lastname: Leys
authors.forename: F
authors.initials: F
authors.lastname: Mounier-Vehier
authors.forename: D
authors.initials: D
authors.lastname: Bertheloot
authors.forename: E
authors.initials: E
authors.lastname: Lartigau
authors.forename: J P
authors.initials: JP
authors.lastname: Pruvo
authors.forename: M
authors.initials: M
authors.lastname: Al-Koussa
authors.forename: D
authors.initials: D
authors.lastname: Chevalier
authors.forename: H
authors.initials: H
authors.lastname: Henon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000706:statistics & numerical data; D016893:Carotid Stenosis / Q000401:mortality*; D015984:Causality; D015897:Comorbidity; D016894:Endarterectomy, Carotid / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000532:radiotherapy; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D016609:Neoplasms, Second Primary / Q000401:mortality*; D011446:Prospective Studies; D011878:Radiotherapy / Q000009:adverse effects*; D012307:Risk Factors; D020521:Stroke / Q000401:mortality*; D016019:Survival Analysis; D016896:Treatment Outcome