Receptors for endogenous and heterogenous hydroxamate siderophores in Staphylococcus aureus B 471.
In Staphylococcus aureus B47 grown in iron-restricted medium, six new, iron-regulated proteins occurred in cytoplasmic membrane. Protein of 14kDa has bound two complexes of iron: Fe(III)-staphylobactin and Fe(III)-acinetoferrin. Complexes of Fe(llI)-ferrichrome and Fe(III)-rhodotorulic acid were not bound to any of new membrane protein. Iron of Fe(III)-staphylobactin and Fe(IIl)-acinetoferrin complexes was transported into the cells.
Wysocki
Piotr
P
Chair of Biology and Biotechnology, Department of Pharmaceutical Microbiology, Medical University of Lódź, Pomorska 137, 90-235 Lódź, Poland. pwysocki@pharm.am.lodz.pl
Lisiecki
Paweł
P
Mikucki
Jerzy
J
D002462:Cell Membrane / Q000378:metabolism; D003470:Culture Media; D005290:Ferric Compounds / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D006877:Hydroxamic Acids / Q000378:metabolism*; D007501:Iron / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism*; D017262:Siderophores / Q000378:metabolism*; D013211:Staphylococcus aureus / Q000254:growth & development / Q000378:metabolism*
D003470:Culture Media; D005290:Ferric Compounds; D006877:Hydroxamic Acids; D011956:Receptors, Cell Surface; D017262:Siderophores; C074579:iron (III) hydroxamate; D007501:Iron