[Insulin-like growth factor and interacting proteins].
Insulin-like growth factor - IGF-I is a small, 70 aminoacid mitogenic peptide, contributing to processes of growing, cancerogenesis, apoptosis, wound healing and many others. It constitutes so called 'somatotropic axis GH-IGF', composed of many other components. This axis is responsible for regulation of metabolic processes, and its proper functioning conditions organism's homeostasis. Presented work describes concise review of publications concerning IGF-I structure, function, expression and proteins affecting its activity, synthesis and circulation.
Obrepalska-Steplowska
Aleksandra
A
Interdepartmental Laboratory of Molecular Biology, Plant Protection Institute, 20 Miczurina St., 60-318 Poznan, Poland. ao.steplowska@ior.poznan.pl
Durzyński
Lukasz
L
Goździcka-Józefiak
Anna
A
D015870:Gene Expression; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*
D007334:Insulin-Like Growth Factor I