title: Nasal pain disrupting sleep as a presenting symptom of extraesophageal acid reflux in children.
abstract: A constellation of otolaryngologic signs and symptoms has been suggested to identify the association between extraesophageal reflux disease (EERD) and pediatric otolaryngologic disorders. We describe chronic nasal pain as a manifestation of laryngopharyngeal acid reflux in a 4-year-old boy who presented with frequent night awakenings due to severe nasal pain. His presentation, relevant history physical examination, diagnostic studies, and response to therapy are described. This is the first report documenting nasal pain resolved with acid suppressive therapy in a child with EERD. The incidence and pathogenesis of EERD induced nasal symptoms in children merits further investigation.
authors.affiliation: Department of Otolaryngology, University at Buffalo, School of Medicine and Biomedical Sciences and the Women and Children's Hospital, 219 Bryant Street, Buffalo, NY 14209, USA.
authors.forename: Seckin
authors.initials: S
authors.lastname: Ulualp
authors.forename: Linda
authors.initials: L
authors.lastname: Brodsky
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002675:Child, Preschool; D004032:Diet; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000628:therapy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006685:Hoarseness / Q000209:etiology; D006801:Humans; D064747:Lansoprazole; D008019:Life Style; D008297:Male; D009296:Nasal Cavity / Q000503:physiopathology*; D009853:Omeprazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D010146:Pain / Q000209:etiology* / Q000503:physiopathology; D054328:Proton Pump Inhibitors; D011899:Ranitidine / Q000627:therapeutic use; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology* / Q000503:physiopathology; D012913:Snoring / Q000209:etiology
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors; D064747:Lansoprazole; D011899:Ranitidine; D009853:Omeprazole