title: Organocatalytic asymmetric Michael addition of 2,4-pentandione to nitroolefins.
abstract: [reaction: see text] A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.
authors.affiliation: Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Wenhu
authors.initials: W
authors.lastname: Duan
authors.forename: Liansuo
authors.initials: L
authors.lastname: Zu
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D009574:Nitro Compounds / Q000737:chemistry*; D010422:Pentanones / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
chemical_list: D000475:Alkenes; D009281:Naphthalenes; D009574:Nitro Compounds; D010422:Pentanones; C008790:acetylacetone; D013890:Thiourea