title: Advantages of short-time ureteric stenting for prevention of urological complications in kidney transplantation: an 18-year experience.
abstract: We retrospectively studied the incidence of urological complications in a consecutive series of 590 patients (group B) who received a kidney transplant (KT) with a ureteral stent from January 1994 to December 2002. The ureteral stent was sewn to the bladder catheter during the surgical procedure and left in situ for a mean time of 10 days (range 8 to 12 days). The results were compared to a consecutive series of 414 patients who received a KT from March 1986 to December 1993 without a ureteral stent (group A). The two groups were comparable in terms of donor and recipient gender, ischemia time, delayed graft function, and chronic rejection incidence, but differed in mean donor age (44.1 vs 36.0 years), mean recipient age (45.4 vs 39.1 years), living/cadaveric donor rate (19.8% vs 11.9%), arterial lesions and bench reconstruction rate (11.1 vs 3.5%), as well as acute rejection episodes (11.7% vs 29.2%). Complications were seen in nine patients in group B (1.5%) and 17 patients in group A (4.1%) (P < .0001). Urinary leaks presented in two patients in group B (0.3%) and 11 patients in Group A (2.6%; P < .0001), while stenosis was present in six patients in group B (1.5%) and 7 in group A (1.2%) (P = NS). Urological complications such as urinary tract infection and macroscopic hematuria were similar in both groups. Time to presentation of a leak was within 2 weeks from KT in 10 patients (92.3%), while stenosis presented early in four patients (one in group B and four in group A). Of the stenoses, 69.3% presented late (beyond 12 weeks) in five patients in group B and three in Group A. In conclusion, our data suggest that routine use of double pigtail ureteral stent significantly decreased the incidence of leaks and early stenoses, but it did not modify late stenosis incidence. In the last decade, risk factors for urological complications have been increasing over time, namely, older donors and older recipients, living donation, length of dialysis, and the use of grafts with arterial lesions. Therefore we believe that a ureteral stent should be routinely considered to afford the advantage to protect the urinary anastomosis in the early postoperative period when the incidence of complications is highest, without the need of cystoscopy for its removal.
authors.affiliation: Kidney and Pancreas Transplantation Unit, Niguarda Hospital, Milan, Italy.
authors.forename: C V
authors.initials: CV
authors.lastname: Sansalone
authors.forename: G
authors.initials: G
authors.lastname: Maione
authors.forename: P
authors.initials: P
authors.lastname: Aseni
authors.forename: I
authors.initials: I
authors.lastname: Mangoni
authors.forename: S
authors.initials: S
authors.lastname: Soldano
authors.forename: E
authors.initials: E
authors.lastname: Minetti
authors.forename: L
authors.initials: L
authors.lastname: Radaelli
authors.forename: G
authors.initials: G
authors.lastname: Civati
mesh_terms: D005260:Female; D006084:Graft Rejection / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000379:methods* / Q000401:mortality; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D016019:Survival Analysis; D014513:Ureter / Q000601:surgery*; D001743:Urinary Bladder / Q000601:surgery; D014552:Urinary Tract Infections / Q000453:epidemiology; D014570:Urologic Diseases / Q000517:prevention & control*