[Seringueira's latex membrane (Hevea brasiliensis) with and without polylysine 0.1% and marlex mesh for the reconstruction of iatrogenics abdominal wall defects in rats].
OBJECTIVE
To compare seringueira latex membrane implant, with and without polylysine at 0.1% and marlex mesh on the repair of iatrogenic abdominal defects in rats.


METHODS
A circular segment block of approximate three centimeters of diameter was sectioned out of the ventral abdominal muscle wall of 31 Wistar rats. The skin was preserved. The animals were divided into three experimental groups: only latex, latex and polylysine at 0.1%, and marlex mesh. Some rats underwent euthanasia at five and some at 120 days after surgery. Fragments of abdominal wall were collected and submitted at histopathologic analysis.


RESULTS
The main alterations observed in groups treated with the latex membrane with and without polylysine were dehiscence (21 animals) and evisceration (two animals). The elimination of implant occurred at an average of 13.8 days. These animals presented fiber conjunctive tissue formation, similar to that observed in the group which received the marlex mesh. Other alterations noted were viscera-parietal adherences in all evaluated groups.


CONCLUSIONS
The seringueira' s latex membrane, with or without polylysine 0.1%, when used on the reconstruction of abdominal defects in rats is eliminated at 13.8 days after its implantation, leaving a fiber base of reparation, similar to that observed after marlex mesh implantation.
Paulo
Neusa Margarida
NM
Laboratório de Cirurgia Experimental, Escola de Veterinária, UFG. nmp@vet.ufg.br
Lima
Flávia Gontijo de
FG
Siqueira Júnior
Juarez Távora de
JT
Fleury
Luiz Fernando Froes
LF
Sant' Ana
Fabiano José Ferreira de
FJ
Borges
Alinne Cardoso
AC
Telles
Thalita da Costa
Tda C
D034861:Abdominal Wall / Q000473:pathology* / Q000601:surgery; D000818:Animals; D028482:Hevea; D007049:Iatrogenic Disease; D007840:Latex; D008297:Male; D011107:Polylysine / Q000627:therapeutic use*; D011126:Polypropylenes / Q000627:therapeutic use*; D019736:Prostheses and Implants; D051381:Rats; D017208:Rats, Wistar; D019651:Plastic Surgery Procedures; D013526:Surgical Mesh; D013997:Time Factors; D014945:Wound Healing / Q000502:physiology
D007840:Latex; D011126:Polypropylenes; D011107:Polylysine