title: Doppler-echocardiographic characteristics of left ventricular function in patients with pseudoexfoliation glaucoma: a preliminary report.
abstract: Glaucoma is associated with an increased incidence of cardiovascular disease and risk factors. The aim of the study was to assess the left ventricular (LV) function in patients with pseudoexfoliation (PEX) glaucoma using doppler-echocardiographic examinations. Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed in 21 patients with (PEX) glaucoma and 24 controls. LV systolic contraction and ejection were assessed using the LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling assessed parameters were: early, fast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velocity time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE /VTIA), pressure at the end of filling (LVEDP) and a pulmonary capillary wedge pressure (PCWP). A significant difference was found concerning LV filling flow parameters in E, E/A, VTIA and ratio VTIA/ VTIE. No significant difference was found in EF, FS, A, VTIE, LVEDP and PCWP tested parameters. Our study indicates the possibility of slightly impaired diastolic function of LV in patients with PEX glaucoma assessed by Doppler-echocardiographic examinations.
authors.affiliation: University Department of Ophthalmology, Clinical Hospital Split, Split, Croatia. lovreb@kbsplit.hr
authors.forename: Lovro
authors.initials: L
authors.lastname: Bojić
authors.forename: Ratko
authors.initials: R
authors.lastname: Ermacora
authors.forename: Milan
authors.initials: M
authors.lastname: Ivanisević
authors.forename: Davor
authors.initials: D
authors.lastname: Galetović
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
authors.forename: Katia
authors.initials: K
authors.lastname: Novak-Laus
authors.forename: Branimir
authors.initials: B
authors.lastname: Cerovski
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D017523:Croatia / Q000453:epidemiology; D015150:Echocardiography, Doppler; D017889:Exfoliation Syndrome / Q000150:complications*; D005260:Female; D005901:Glaucoma / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018709:Statistics, Nonparametric; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000453:epidemiology