[A case of pseudothrombocytopenia due to platelet cold agglutinins].
We report a case of pseudothrombocytopenia due to platelet cold agglutinins. Platelet counts were decreased in blood drawn in a tube without anti-coagulant just after withdrawal as well as in blood drawn in a tube with anti-coagulant, such as EDTA-2K, MgSO4, citrate or heparin. In our case, platelet aggregates were noted on blood-smear made from blood samples obtained with and without anti-coagulant. RBC and WBC counts were within the normal range. Platelet aggregates mainly consisted of 2-5 platelets. Patient plasma agglutinated normal platelets at a temperature below 10 degrees C. Immunoglobulin class was determined as IgM by flow cytometry.
Hayashi
Satoru
S
Department of Blood Transfusion, Osaka University Hospital, Suita 565-0871.
Nishiyama
Miho
M
Jouzaki
Kiyoshi
K
Tomiyama
Yoshiaki
Y
Kurata
Yoshiyuki
Y
D003450:Cryoglobulins / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D010974:Platelet Aggregation; D013921:Thrombocytopenia / Q000175:diagnosis*
D003450:Cryoglobulins; C029443:cold agglutinins