title: Lipoblastoma/lipoblastomatosis: a clinicopathologic study of 16 cases in Taiwan.
abstract: Lipoblastoma/lipoblastomatosis is an uncommon benign lipomatous tumor affecting mainly infants and children. It presents as a painless mass located frequently in upper and lower extremities. The present study was conducted to characterize the clinicopathologic features of lipoblastoma/lipoblastomatosis in a Chinese population. A retrospective survey of 16 cases of pathologically confirmed lipoblastoma/lipoblastomatosis from 1988 to 2002 was performed. The available clinical information and histological sections were reviewed. The study involved 10 males and 6 females ranging in age from 5 to 49 months (median, 11.5 months). The patients presented with mass involving neck (n = 5), inguina (n = 3), feet (n = 2), arm (n = 1), leg (n = 1), thorax (n = 1), mesentery (n = 1), buttock (n = 1), and presacral region (n = 1). The lesions were removed surgically. Histologically, the majority (11/16) of primary tumors were of diffuse type. Follow-up ranging from 5 to 125 months was available in 13 patients. Four patients experienced a recurrence of tumors in the neck (n = 2) and lower extremities (n = 2) 11-84 months after operation. The most common site of involvement of lipoblastoma/lipoblastomatosis in our series was the neck. A follow-up period of more than 3 years is recommended for patients with this condition.
authors.affiliation: Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Hsin, Kwei San, Taoyuan 333, Taiwan.
authors.forename: Shih-Ming
authors.initials: SM
authors.lastname: Jung
authors.forename: Pei-Yeh
authors.initials: PY
authors.lastname: Chang
authors.forename: Chih-Cheng
authors.initials: CC
authors.lastname: Luo
authors.forename: Chen-Sheng
authors.initials: CS
authors.lastname: Huang
authors.forename: Jin-Yao
authors.initials: JY
authors.lastname: Lai
authors.forename: Chuen
authors.initials: C
authors.lastname: Hsueh
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery