title: Wake-up call for Sleeping Beauty.
abstract: By tinkering with the transposon Sleeping Beauty, researchers have developed new, highly effective strategies for performing mammalian mutagenesis screens.
authors.forename: Michael
authors.initials: M
authors.lastname: Eisenstein
mesh_terms: D000818:Animals; D004252:DNA Mutational Analysis / Q000379:methods*; D004251:DNA Transposable Elements / Q000235:genetics*; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D016297:Mutagenesis, Site-Directed / Q000235:genetics*; D019895:Transposases / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D019895:Transposases; C494471:sleeping beauty transposase, human