Spatial memory following prenatal alcohol exposure: more than a material specific memory deficit.
Spatial memory deficits have been reported following prenatal alcohol exposure and animal studies have demonstrated hippocampal vulnerability to alcohol. This study examined spatial memory in children diagnosed with fetal alcohol syndrome (FAS) or fetal alcohol effects (FAE) and matched controls. Spatial memory was examined with location recall measures. Since visual perceptual skills and nonspecific memory impairment could impact spatial memory, tasks assessing perception and verbal memory were administered. Analyses revealed group differences on perceptual and verbal and spatial memory tasks. There was no significant difference in spatial memory once perceptual and verbal memory task performance was taken into account, suggesting that differences in spatial memory were not solely attributable to a material specific memory deficit.
Kaemingk
K L
KL
Department of Pediatrics, University of Arizona, Arizona Health Sciences Center, PO Box 245073, Tucson, AZ 85724, USA. kaemingk@peds.arizona.edu
Halverson
P T
PT
D000293:Adolescent; D002648:Child; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000175:diagnosis* / Q000523:psychology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000523:psychology; D008570:Memory, Short-Term; D011939:Mental Recall; D009483:Neuropsychological Tests; D009949:Orientation; D010364:Pattern Recognition, Visual; D011247:Pregnancy; D014706:Verbal Learning