title: [A clinical study of Safflower Yellow injection in treating coronary heart disease angina pectoris with Xin-blood stagnation syndrome].
abstract: OBJECTIVE
  To evaluate the clinical effect and safety of Safflower Yellow injection (SYI) in treating coronary heart disease angina pectoris (CHD-AP) with Xin-blood stagnation syndrome (XBSS).
  
  
  METHODS
  Adopted was the multi-centered, randomized, positive parallel controlled method, 448 patients with CHD-AP-XBSS were enrolled and divided into two groups, 336 in the tested group treated with SYI and 112 in the control group treated with Salvia injection by intravenous dripping once a day for 14 days, so as to observe the conditions of angina, electrocardiogram, and therapeutic effect on traditional Chinese medicine (TCM) symptoms as well as the safety of the treatment.
  
  
  RESULTS
  The significantly effective rate and total effective rate in the tested group were 60.06% (194/323) and 91.02% (294/323) respectively; Those in improvement of TCM symptoms were 40.18% (129/321) and 75.23% (243/323) respectively, which were better than those in the control group (P < 0.01).
  
  
  CONCLUSIONS
  SYI Injection is effective and safe in treating CHD-AP-XBSS.
authors.affiliation: The National Clinical Base of Drug Research, Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing 100091, China. zhangq810@263.net
authors.forename: Qiong
authors.initials: Q
authors.lastname: Zhang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Peng
authors.forename: Xiang-nong
authors.initials: XN
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D002599:Chalcone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D008517:Phytotherapy; D028321:Plant Preparations; D027544:Salvia; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; D028321:Plant Preparations; C076422:safflower yellow; D002599:Chalcone