Live chemical reports from the cell surface.
Understanding the dynamic roles that proteins play in cell biology requires tools to selectively label these biomolecules in living systems. Yin and colleagues [1] showcase the power of a novel chemical labeling technology for tracking receptor-ligand interactions in native cellular environments.
Cravatt
Benjamin F
BF
The Skaggs Institute for Chemical Biology, Department of Cell Biology and Chemistry, The Scripps Research Institute, La Jolla, California 92037, USA.
D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism*; D008024:Ligands; D011485:Protein Binding; D011990:Receptors, Transferrin / Q000378:metabolism
D008024:Ligands; D011990:Receptors, Transferrin