title: [Anaplastic thyroid tumor: retrospective analysis of 12 cases].
abstract: Anaplastic thyroid tumor is a rare tumor and constitutes 5 to 10% of thyroid carcinomas. Is one of the most aggressive solid tumors and the prognosis is always fatal with a mean survival of 3 to 7 months. The current therapeutics are scarce and inefficacious. A retrospective analysis was performed in 12 clinical cases of anaplastic thyroid tumor observed at the Department of Endocrinology, Diabetes and Metabolism of the University Hospital of Coimbra. We analysed data relative to sex, previous thyroid pathology, clinical signs and symptoms, date of diagnosis, treatment and outcome. In this series, the anaplastic thyroid carcinoma showed to be a highly malignant tumor with a mortality rate of 100% with a survival after the diagnosis between 15 days and 9 months.
authors.affiliation: Serviço de Endocrinologia Diabetes e Metabolismo, Hospitais da Universidade de Coimbra, Coimbra.
authors.forename: Teresa D
authors.initials: TD
authors.lastname: Martins
authors.forename: Francisco
authors.initials: F
authors.lastname: Carrilho
authors.forename: Patrícia
authors.initials: P
authors.lastname: Leitão
authors.forename: Manuel C
authors.initials: MC
authors.lastname: Lemos
authors.forename: Maria V
authors.initials: MV
authors.lastname: Campos
authors.forename: Elizabete
authors.initials: E
authors.lastname: Geraldes
authors.forename: Manuela
authors.initials: M
authors.lastname: Carvalheiro
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000628:therapy