title: Serum sickness and uveitis.
abstract: Serum sickness is immune response to a foreign antigen, usually a heterologous protein. Incidence rate is less than 0.5%. Antigens and responding antibodies form circulating immunocomplex that is characteristic for serum sickness. The condition occurs 7-15 days after exposure to the antigen, usually with clinical picture of glomerulonephritis. The immunocomplex circulates to other tissues where it sediments and causes inflammation, such as arteritis, neuritis, synovitis. The aim of this research is to present the break out of serum sickness in form of anterior uveitis due to azithromycin therapy administered by mouth. Identifying of anterior uveitis may help in early diagnostics and treatment of serum sickness.
authors.affiliation: Department of Ophthalmology, Clinical Hospital Osijek, Osijek, Croatia.
authors.forename: Dubravka
authors.initials: D
authors.lastname: Biuk
authors.forename: Tomislav
authors.initials: T
authors.lastname: Jukić
authors.forename: Nenad
authors.initials: N
authors.lastname: Vukojević
authors.forename: Miro
authors.initials: M
authors.lastname: Kalauz
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D017963:Azithromycin / Q000009:adverse effects*; D002648:Child; D006801:Humans; D008297:Male; D012713:Serum Sickness / Q000150:complications*; D014605:Uveitis / Q000139:chemically induced* / Q000276:immunology
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin