title: Huge bilateral pulmonary and pleural metastasis from intracranial meningioma: a case report and review of the literature.
abstract: A case of recurrent meningioma with atypical features and extracranial metastases is reported. A 34-year-old female was operated in 1996, 2000, and 2002, and frontal parasagittal meningioma was extirpated. Histological diagnoses of all the resected tumors were meningotheliomatous meningioma, WHO Grade I. However, 2 years later, the tumor recurred in the frontal scalp and was removed again totally. Histological diagnosis was reported as an atypical meningioma; meningotheliomatous type; WHO Grade II. She received radiation therapy. But the tumor had metastasized to the lung and pleura. Transthoracic tru-cut biopsy was performed from large mass of the left lung. Cytopathology was consistent with malignant meningioma, metastasis from the patient's known intracranial meningioma. Ki-67 staining index at the primary and metastatic sites of the present cases were 7 and 5%, respectively. We reviewed and discussed the histopathological features and mechanisms of metastasizing meningioma.
authors.affiliation: Department of Neurosurgery, Cukurova University School of Medicine, Balcali, 01330 Adana, Turkey. ermant@cu.edu.tr
authors.forename: Tahsin
authors.initials: T
authors.lastname: Erman
authors.forename: Ismail
authors.initials: I
authors.lastname: Hanta
authors.forename: Sebahattin
authors.initials: S
authors.lastname: Haciyakupoğlu
authors.forename: Suzan
authors.initials: S
authors.lastname: Zorludemir
authors.forename: Handan
authors.initials: H
authors.lastname: Zeren
authors.forename: A Iskender
authors.initials: AI
authors.lastname: Göçer
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000556:secondary*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D014057:Tomography, X-Ray Computed