Spontaneous splenic rupture associated with hepatosplenic gammadelta T-cell lymphoma.
Spontaneous splenic rupture is an uncommon but life-threatening complication of hematologic malignancies, despite the frequent involvement of the spleen in these diseases. It has been reported in patients with acute and chronic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma, and histiocytic lymphoma. A 50-year-old previously healthy man presented with acute symptoms of spontaneous splenic rupture. Emergency splenectomy with liver biopsy was performed. The clinicopathologic features suggested a hepatosplenic gammadelta T-cell lymphoma (HSgammadeltaTL). Here, we report a rare case of spontaneous splenic rupture associated with HSgammadeltaTL, unspecified in the World Health Organization classification.
Chen
Jia-Hui
JH
Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chan
De-Chuan
DC
Lee
Herng-Sheng
HS
Liu
Hsiao-Dung
HD
Hsieh
Chung-Bao
CB
Yu
Jyh-Cherng
JC
Liu
Yao-Chi
YC
Chen
Cheng-Jueng
CJ
D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D016411:Lymphoma, T-Cell, Peripheral / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013160:Splenic Neoplasms / Q000150:complications* / Q000473:pathology; D013161:Splenic Rupture / Q000209:etiology*; D013163:Splenomegaly / Q000209:etiology