title: Improved excitation schemes for multiple-quantum magic-angle spinning for quadrupolar nuclei designed using optimal control theory.
abstract: We have investigated the use of optimal control theory for the design of improved multiple-quantum excitation schemes for the popular multiple-quantum magic-angle spinning NMR experiment for quadrupolar nuclei with half-integer quadrupolar spin. The advantage of the new low-power experiments, termed OCFASTER, is demonstrated by sensitivity improvements approaching 50% for 87Rb in RbClO4 and RbNO3 as compared to FASTER and standard strong-pulse excitation schemes.
authors.affiliation: Center for Insoluble Protein Structures (inSPIN), University of Aarhus, DK-8000 Aarhus C, Denmark. tv@chem.au.dk
authors.forename: Thomas
authors.initials: T
authors.lastname: Vosegaard
authors.forename: Cindie
authors.initials: C
authors.lastname: Kehlet
authors.forename: Navin
authors.initials: N
authors.lastname: Khaneja
authors.forename: Steffen J
authors.initials: SJ
authors.lastname: Glaser
authors.forename: Niels Chr
authors.initials: NC
authors.lastname: Nielsen
mesh_terms: D003198:Computer Simulation; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D008962:Models, Theoretical; D011786:Quality Control; D011789:Quantum Theory; D012015:Reference Standards; D012680:Sensitivity and Specificity