Association of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse in Singapore.
The relationship of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse was examined. Beijing strains were detected from 32 out of 45 (71%) relapsed cases and 148 out of 290 (51%) non-relapsed cases. Multivariate logistic regression analysis revealed that Beijing genotype was significantly associated with tuberculosis relapse (OR 2.64, 95% CI 1.30-5.34, P=0.005).
Sun
Y-J
YJ
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore. Yong_Jiang_Sun@ttsh.com.sg
Lee
A S G
AS
Wong
S-Y
SY
Paton
N I
NI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000472:pathogenicity*; D016017:Odds Ratio; D012008:Recurrence; D012846:Singapore / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000235:genetics* / Q000473:pathology*