title: Indirect determination of neomycin trisulphate as sulphate by column coupling capillary isotachophoresis.
abstract: Anionic capillary isotachophoresis (cITP) with conductometric detection was used for indirect determination of neomycin trisulphate (NMS) as sulphate anion. The following electroylets were tested: leading (LE)--8 mM HCl adjusted with beta-alanine to pH = 3.55, 3 mM bis-tris-propane and 0.2% hydroxyethylcellulose and terminating (TE): 5 mM citric acid; 5 mM formic acid and 5 mM caproic acid. The calibration graphs of sulphates concentration were linear in the range 3.55 to 25.90 mg/dm3 with recoveries between 94.50-99.70%. The method was tested on pharmaceutical preparation Enterogast.
authors.affiliation: Faculty of Chemistry, Nicolaus Copemicus University, 87-100 Toruń, 7 Gagarina Str., Poland. jmk@cc.uni.torun.pl
authors.forename: Marzanna
authors.initials: M
authors.lastname: Kurzawa
authors.forename: Aneta
authors.initials: A
authors.lastname: Jastrzebska
authors.forename: Edward
authors.initials: E
authors.lastname: Szłyk
mesh_terms: D019075:Electrophoresis, Capillary / Q000379:methods*; D009355:Neomycin / Q000032:analysis*; D013431:Sulfates / Q000032:analysis
chemical_list: D013431:Sulfates; D009355:Neomycin