Palladium catalyzed alkenyl amination: from enamines to heterocyclic synthesis.
The most recent advances in the Pd catalyzed amination of alkenyl halides directed towards the synthesis of imines and enamines are reviewed. The application of this cross-coupling reaction in the synthesis of heterocycles appears to be a potentially powerful methodology. The few examples already available are also discussed.
Barluenga
José
J
Instituto Universitario de Química Organometálica Enrique Moles, Universidad de Oviedo, Julián Clavería 8, Oviedo, 33006, Spain. barluenga@uniovi.es
Valdés
Carlos
C
D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D001393:Azoles / Q000737:chemistry; D001965:Bromides / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D007536:Isomerism; D008024:Ligands; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*
D000475:Alkenes; D001393:Azoles; D001965:Bromides; D008024:Ligands; D011725:Pyridines; D010165:Palladium; D002244:Carbon; D009584:Nitrogen