title: Controversies in diagnostic approaches to the indeterminate follicular thyroid nodule.
abstract: In this paper we review the controversies in diagnostic approaches to follicular thyroid nodules with indeterminate cytology. The authors consider some of the controversies surrounding the indeterminate follicular thyroid nodule, including the definition and the postoperative outcome. Among the techniques that may improve preoperative diagnostic accuracy are large needle aspiration biopsy and immunohistochemistry for galectin-3.
authors.affiliation: Internal Medicine Department, University of Pisa Medical School, Pisa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Carpi
authors.forename: A
authors.initials: A
authors.lastname: Nicolini
authors.forename: M D
authors.initials: MD
authors.lastname: Gross
authors.forename: L M
authors.initials: LM
authors.lastname: Fig
authors.forename: B
authors.initials: B
authors.lastname: Shapiro
authors.forename: S
authors.initials: S
authors.lastname: Fanti
authors.forename: L
authors.initials: L
authors.lastname: Rampin
authors.forename: C
authors.initials: C
authors.lastname: Polico
authors.forename: D
authors.initials: D
authors.lastname: Rubello
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000473:pathology; D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology; D018265:Carcinoma, Papillary, Follicular / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D011300:Preoperative Care; D016606:Thyroid Nodule / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery