title: Dystrophic xanthomatosis in primary CD30-positive cutaneous T-cell lymphoma. Report of two cases and review of the literature.
abstract: The development of xanthomatous changes in lesions of primary cutaneous T-cell lymphomas (CTCL) is a rare event. It is usually observed in regressing skin tumours or plaques spontaneously or after a specific treatment. The pathogenetic mechanisms implicated in these changes are poorly understood. We are reporting 2 cases of extensive dystrophic xanthomatous changes, developing in regressing lesions of primary cutaneous CD30-positive T-cell lymphoproliferative disorders. Previously reported cases of primary CTCL developing secondary (dystrophic) xanthomata are reviewed.
authors.affiliation: Department of Dermatology, Hospital de Bellvitge, Barcelona, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Giménez
authors.forename: Fernando
authors.initials: F
authors.lastname: Gallardo
authors.forename: Neus
authors.initials: N
authors.lastname: Curcó
authors.forename: Joaquim
authors.initials: J
authors.lastname: Marcoval
authors.forename: Vicenç
authors.initials: V
authors.lastname: Romagosa
authors.forename: Octavio
authors.initials: O
authors.lastname: Servitje
authors.forename: Ramon M
authors.initials: RM
authors.lastname: Pujol
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D006801:Humans; D017730:Ki-1 Antigen / Q000276:immunology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications / Q000276:immunology / Q000628:therapy*; D008297:Male; D014973:Xanthomatosis / Q000209:etiology*
chemical_list: D017730:Ki-1 Antigen