title: Obesity and functional decline: epidemiology and geriatric consequences.
abstract: Obesity is growing in prevalence among older Americans and is accompanied by an unfortunate burden of chronic disease, functional decline, and poor quality of life. Elevated past or current body mass index (BMI) is strongly associated with increased self-reported functional limitations. Supportive findings have also related decreased physical performance test scores with elevated BMI. Body composition analyses have explored which body compartment is most strongly associated with obesity-related functional impairments. Studies have suggested possible contributions of decreased muscle mass and increased fat mass. Weight reduction intervention studies that have examined functional outcomes among older persons are limited.
authors.affiliation: Vanderbilt Center for Human Nutrition, 514 Medical Arts Building, Nashville, TN 37212, USA.
authors.forename: Gordon L
authors.initials: GL
authors.lastname: Jensen
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D001823:Body Composition; D016330:Frail Elderly; D006801:Humans; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D015431:Weight Loss