title: Successful treatment of lymphadenosis benigna cutis with topical photodynamic therapy with delta-aminolevulinic acid.
abstract: BACKGROUND
  Photodynamic therapy (PDT) using topical delta-aminolevulinic acid (ALA) has been used for nonmelanoma skin cancers, including malignant cutaneous T-cell lymphomas. Moreover, PDT has been tried for benign inflammatory or infectious skin lesions.
  
  
  OBJECTIVE
  To evaluate the effects of ALA-PDT on skin lesions of lymphadenosis benigna cutis (LABC).
  
  
  METHODS
  Two 16-year-old females with solitary and infiltrated nodules were treated 5 times with topical ALA-PDT.
  
  
  RESULTS
  Both patients responded well and showed dramatic clinical and histopathological improvement without visible scars.
  
  
  CONCLUSIONS
  The results confirm that topical ALA-PDT is an effective and safe modality for the treatment of LABC, and that such treatment may be cosmetically beneficial.
authors.affiliation: Department of Dermatology, Hirosaki University School of Medicine, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Takeda
authors.forename: Takahide
authors.initials: T
authors.lastname: Kaneko
authors.forename: Ken
authors.initials: K
authors.lastname: Harada
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Matsuzaki
authors.forename: Hajime
authors.initials: H
authors.lastname: Nakano
authors.forename: Katsumi
authors.initials: K
authors.lastname: Hanada
mesh_terms: D000293:Adolescent; D000622:Aminolevulinic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D019310:Pseudolymphoma / Q000150:complications / Q000188:drug therapy*; D012871:Skin Diseases / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid