Falsely high glycated haemoglobin [HbA1C] because of haemoglobin OSU-Christiansborg.
Glycated haemoglobin (HbA1c) is routinely used to assess the degree of glycaemic control in diabetic patients. We report a case of a 73 year old diabetic woman who had an elevated HbA1c of 13.4%. She was on maximum oral hypoglycaemic agents and was commenced on insulin. However, her HbA1c continued to remain high at 20.4%. Subsequent tests revealed that she had a haemoglobin variant, Haemoglobin Osu-Christiansborg, causing the falsely high glycated haemoglobin.
Kapoor
D
D
Centre for Diabetes and Endocrinology, Department of Haematology, Barnsley District General Hospital, Barnsley, UK. drdkapoor@yahoo.co.uk
Ng
J P
JP
Jones
T H
TH
D000368:Aged; D003920:Diabetes Mellitus / Q000175:diagnosis; D005189:False Positive Reactions; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006453:Hemoglobinopathies / Q000175:diagnosis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D006943:Hyperglycemia / Q000175:diagnosis*; D007004:Hypoglycemic Agents / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology
D006442:Glycated Hemoglobin; D006455:Hemoglobins, Abnormal; D007004:Hypoglycemic Agents; D007328:Insulin; C119901:hemoglobin Osu-Christiansborg