Bleeding diathesis in Noonan syndrome.
An 18-year-old girl with Noonan syndrome was operated on for prominent ears. Subcutaneous haematomas developed on both sides, and coagulation tests reported a bleeding diathesis. This is seldom mentioned in descriptions of the syndrome, but it has been shown that one-third of all patients with the syndrome have defects in haemostasis. Extended screening is therefore useful.
Staudt
Joost M
JM
Department of Plastic and Reconstructive Surgery and Hand Surgery, Academical Medical Centre, Amsterdam, The Netherlands. joost@staudt.nl
Van der Horst
Chantal M A M
CM
Peters
Marjolijn
M
Melis
Paris
P
D000293:Adolescent; D005260:Female; D006474:Hemorrhagic Disorders / Q000150:complications*; D006801:Humans; D009634:Noonan Syndrome / Q000150:complications*