A novel spin trap for targeting sulfhydryl-containing polypeptides.
A novel spin trap containing an iodoacetamide group has been synthesized and then used to target polypeptides, i.e. glutathione and bovine serum albumin, by which the resulting covalently bonded bioconjugates exhibit great potential for the application of spin trapping of transient radicals in biological systems.
Liu
Yang Ping
YP
State Key Laboratory for Structural Chemistry of Unstable Species, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100080, China.
Ji
Yi Qiong
YQ
Song
Yu Guang
YG
Liu
Ke Jian
KJ
Liu
Bin
B
Tian
Qiu
Q
Liu
Yang
Y
D000818:Animals; D002417:Cattle; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry*; D013057:Spectrum Analysis; D013113:Spin Labels; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D010455:Peptides; D013113:Spin Labels; D013438:Sulfhydryl Compounds