title: [Tuberculoma complicating tuberculous meningitis: description of one paediatric case].
abstract: Intracranial tuberculoma is a possible complication of meningeal, miliary or pulmonary tuberculosis. In developing countries it represents 30% of space-occupying intracranial lesions, in industrialised countries only 0.1-0.2%. One recently recognised phenomenon is the development ex novo or the enlargement of the tuberculoma during antitubercular chemo-antibiotic therapy. Here we report the clinical case of an immunocompetent Italian baby girl who presented an intracranial tuberculoma during tuberculous meningitis. We underline how such an event is possible, the need for early neuroradiological evaluation and its favourable course, maintaining adequate antitubercular therapy associated with steroid therapy.
authors.affiliation: U.O. di Clinica Pediatrica, Dipartimento di Scienze Pediatriche Mediche e Chirurgiche, Università degli Studi di Messina, Messina. cruggeri@unime.it
authors.forename: C
authors.initials: C
authors.lastname: Ruggeri
authors.forename: M
authors.initials: M
authors.lastname: Valenzise
authors.forename: M M
authors.initials: MM
authors.lastname: Alosi
authors.forename: G
authors.initials: G
authors.lastname: Scibilia
authors.forename: M
authors.initials: M
authors.lastname: Wasniewska
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000904:Antibiotics, Antitubercular / Q000008:administration & dosage / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D011718:Pyrazinamide / Q000008:administration & dosage / Q000627:therapeutic use; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D013307:Streptomycin / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D016862:Tuberculoma, Intracranial / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014390:Tuberculosis, Meningeal / Q000150:complications* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D011241:Prednisone; D012293:Rifampin; D013307:Streptomycin