Intramolecular additions of alcohols and carboxylic acids to inert olefins catalyzed by silver(I) triflate.
[reactions: see text] Intramolecular additions of hydroxyl or carboxyl groups to inert olefins catalyzed by simple silver(I) triflate are described. Good to excellent yields can be obtained for a range of substrates under relatively mild conditions. This reaction represents one of the simplest methods to construct cyclic ethers or lactones.
Yang
Cai-Guang
CG
Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
Reich
Nicholas W
NW
Shi
Zhangjie
Z
He
Chuan
C