title: Prevalence of carotid artery stenosis in patients with coronary artery disease in Japanese population.
abstract: OBJECTIVE
  Prevalence of carotid artery stenosis in patients with coronary artery disease (CAD) is unknown in Japanese population.
  
  
  METHODS
  The study populations consisted of 632 consecutive patients who underwent coronary angiography because of suspicion of CAD. All patients underwent carotid ultrasonography to screen carotid artery stenosis before coronary angiography. We defined echographic carotid stenosis as area stenosis of >50% or peak systolic velocity of >200 cm/s.
  
  
  RESULTS
  Echographic carotid stenosis was observed in 124 patients (19.6%). Coronary angiography revealed 433 patients had CAD. Prevalence of echographic carotid artery stenosis was 14 of 199 (7.0%), 18 of 124 (14.5%), 28 of 131 (21.4%), and 64 of 178 (36.0%) in patients with 0-, 1-, 2-, and 3-vessel CAD, respectively (P<0.0001). The prevalence rate with carotid stenosis and CAD was 25.4%. Multivariate stepwise logistic regression analysis showed that age and the extent of CAD were independently related to the presence of carotid stenosis (P=0.0002 and <0.0001, respectively).
  
  
  CONCLUSIONS
  Prevalence of carotid stenosis in patients with CAD is high in Japan as well as in Western countries. Screening of carotid artery stenosis is recommended especially in older patients with multivessel CAD.
authors.affiliation: Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan. Shuzou_bushido@msn.com
authors.forename: Shuzou
authors.initials: S
authors.lastname: Tanimoto
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ikari
authors.forename: Kengo
authors.initials: K
authors.lastname: Tanabe
authors.forename: Sen
authors.initials: S
authors.lastname: Yachi
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Nakajima
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Nakayama
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Hatori
authors.forename: Gaku
authors.initials: G
authors.lastname: Nakazawa
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Onuma
authors.forename: Yasutomi
authors.initials: Y
authors.lastname: Higashikuni
authors.forename: Hirosada
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Eiichi
authors.initials: E
authors.lastname: Tooda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hara
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D050197:Atherosclerosis / Q000473:pathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003251:Constriction, Pathologic; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D004452:Echocardiography; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D015999:Multivariate Analysis; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014463:Ultrasonography