Photocurable hard and porous biomaterials from ROMP precursors cross-linked with diyl radicals.
A combination of (ROMP) ring-opening metathesis polymerization and diradical (diyl) cross-linking provides a new access to hard biomaterials and potential artificial bone replacements. ROMP was used to construct soft and pliable linear polymers bearing photolabile diazene functions. After treatment with light, a nitrogen aerosol is released throughout the polymer to create desirable porosity, cross-linking, and hardening in a single step. Nonpolymeric mechanistic work supporting these studies was also examined.
Enholm
Eric
E
Department of Chemistry, University of Florida, Gainesville, FL 32611, USA. enholm@chem.ufl.edu
Joshi
Aarti
A
Wright
Dennis L
DL
D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D005740:Gases / Q000737:chemistry; D007094:Imides / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D010782:Photolysis; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D016062:Porosity
D001672:Biocompatible Materials; D005740:Gases; D007094:Imides; D011108:Polymers; C038867:diazene; D009584:Nitrogen