Excitotoxic lesions of the entorhinal cortex leave gustatory within-event learning intact.
The ability of rats with ibotenate lesions of the entorhinal cortex to form memories for events was assessed by using a gustatory within-event learning procedure. Rats first received exposure to 2 events, AX and BY, each composed of a pair of flavors. Following this exposure period, Flavor X alone was paired with the delivery of lithium chloride. Lesioned and control rats showed a greater aversion to A than to B and to AX than to BX. These results challenge theories that suppose that the entorhinal cortex plays a general role in forming representations of patterns of stimulation.
Ward-Robinson
Jasper
J
School of Psychology, Cardiff University, Cardiff, Wales. jwr@psychology.nottingham.ac.uk
Coutureau
Etienne
E
Honey
R C
RC
Killcross
A S
AS
D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal; D001930:Brain Injuries / Q000139:chemically induced / Q000503:physiopathology*; D004193:Discrimination Learning / Q000502:physiology*; D018728:Entorhinal Cortex / Q000187:drug effects / Q000293:injuries / Q000503:physiopathology*; D007051:Ibotenic Acid; D008297:Male; D051381:Rats; D013649:Taste / Q000502:physiology*; D014868:Water Deprivation / Q000502:physiology
D007051:Ibotenic Acid