title: A comparative prospective randomized clinical study of MTA and IRM as root-end filling materials in single-rooted teeth in endodontic surgery.
abstract: OBJECTIVE
  Randomized clinical prospective study to evaluate the application of MTA and IRM as retrograde sealers in surgical endodontics.
  
  
  METHODS
  One hundred single-rooted teeth were surgically treated. After randomization, MTA or IRM was used as a retrosealer. Radiographs were taken 1 week, 3 months, and 1 year postoperatively. Assessment was performed by 2 independent assessors 1 year after surgery. Both treatment groups were homogeneous in their composition, and clinical features and radiographic findings were classified according to Rud's classification.
  
  
  RESULTS
  Complete healing was observed in 64% of the MTA-treated teeth vs 50% of the IRM-treated teeth. Incomplete healing was seen in 28% (MTA) vs 36% (IRM), and unsatisfactory in 6% (MTA) vs 14% (IRM). Only 1 failure was seen (MTA). No statistically significant differences were found between the 2 retrofilling materials.
  
  
  CONCLUSIONS
  As root-end filling materials in this clinical prospective randomized design on single rooted teeth, MTA and IRM had the same clinical effectiveness.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, The Netherlands. j.a.lindeboom@amc.uva.nl
authors.forename: Jerome A H
authors.initials: JA
authors.lastname: Lindeboom
authors.forename: Joost W F H
authors.initials: JW
authors.lastname: Frenken
authors.forename: Frans H M
authors.initials: FH
authors.lastname: Kroon
authors.forename: Hans P
authors.initials: HP
authors.lastname: van den Akker
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds; D017610:Calcium Compounds; D016009:Chi-Square Distribution; D019232:Dental Restoration Failure; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008768:Methylmethacrylates; D008875:Middle Aged; D015588:Observer Variation; D010087:Oxides; D011446:Prospective Studies; D011859:Radiography; D015203:Reproducibility of Results; D012184:Retrograde Obturation / Q000379:methods*; D012387:Root Canal Filling Materials; D017640:Silicates; D014092:Tooth Root / Q000000981:diagnostic imaging; D014945:Wound Healing; D015035:Zinc Oxide-Eugenol Cement
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D008768:Methylmethacrylates; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; D015035:Zinc Oxide-Eugenol Cement; C086631:mineral trioxide aggregate; C031667:IRM cement