Multidimensional modelling of anaerobic granules.
A multispecies, two- and three-dimensional model was developed, based on a previously published planar biofilm model, and the biochemical structure of the ADM1. Several soluble substrates diffuse and react in the granule. Local pH is calculated from acid-base equilibria and charge balance. The model uses individual-based representation of biomass particles within the granule (biofilm), and describes spreading by an iterative pushing technique. The overall computational domain consists of one granule, and is divided into a grid with Cartesian coordinates. The number of grid elements does not limit the number of biomass particles, and it is not necessary to use grid-spreading techniques, such as cellular automata, which result in Cartesian artefacts. The model represents both microscopic and macroscopic features in granule structure, previously observed using in-situ molecular techniques, and can be effectively used to interpret these results.
Picioreanu
C
C
Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 Delft, The Netherlands. c.picioreanu@tnw.tudelft.nl
Batstone
D J
DJ
van Loosdrecht
M C M
MC
D000085:Acetates / Q000378:metabolism; D001421:Bacteria, Anaerobic / Q000502:physiology*; D018441:Biofilms / Q000254:growth & development*; D018533:Biomass; D002087:Butyrates / Q000378:metabolism; D050260:Carbohydrate Metabolism; D006859:Hydrogen / Q000378:metabolism; D018613:Microscopy, Confocal; D008954:Models, Biological; D011422:Propionates / Q000378:metabolism
D000085:Acetates; D002087:Butyrates; D011422:Propionates; D006859:Hydrogen