title: Catalytic decarboxylative sp-sp3 coupling.
abstract: A palladium-catalyzed 1,4-enyne synthesis was developed based the decarboxylative coupling of acetylides with allyl electrophiles. Stereochemical studies have implicated palladium-allyl-acetylides as intermediates. Thus, decarboxylative metalation was established as an environmentally benign alternative to transmetalation from alkynyl tin reagents.
authors.affiliation: Department of Chemistry, University of Kansas, Lawrence, Kansas 66045, USA.
authors.forename: Dinesh Kumar
authors.initials: DK
authors.lastname: Rayabarapu
authors.forename: Jon A
authors.initials: JA
authors.lastname: Tunge