title: Severe sepsis and therapy with activated protein C.
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Parrillo
mesh_terms: D018806:APACHE; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D017277:Drug Approval; D006801:Humans; D011486:Protein C / Q000009:adverse effects / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000009:adverse effects / Q000627:therapeutic use; D018805:Sepsis / Q000188:drug therapy*; D017211:Treatment Failure; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000890:Anti-Infective Agents; D011486:Protein C; D011994:Recombinant Proteins; C421124:drotrecogin alfa activated