title: Successful resection of a hypothalamic hamartoma and a Rathke cleft cyst. Case report.
abstract: The authors report the case of a 12-year-old girl with Pallister-Hall syndrome, long-standing refractory, symptomatic epilepsy, mental retardation, and panhypopituitarism in whom two rare, deep midline lesions were detected. She underwent successful transsphenoidal resection of the Rathke cleft cyst and transcallosal resection of the hypothalamic hamartoma within a 4-day period without complications. Neuropathological studies confirmed the neuroimaging diagnoses for the two lesions. The patient has been seizure free for 6 months postoperatively.
authors.affiliation: Department of Pediatrics, Barrow Neurological Institute, St. Joseph's Hospital, Phoenix, Arizona 85013, USA. y2ng@chw.edu
authors.forename: Yu-tze
authors.initials: YT
authors.lastname: Ng
authors.forename: John F
authors.initials: JF
authors.lastname: Kerrigan
authors.forename: Erin C
authors.initials: EC
authors.lastname: Prenger
authors.forename: William L
authors.initials: WL
authors.lastname: White
authors.forename: Harold L
authors.initials: HL
authors.lastname: Rekate
mesh_terms: D020863:Central Nervous System Cysts / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D012640:Seizures / Q000209:etiology; D016896:Treatment Outcome