Biological activity of bone morphogenetic proteins (BMP's).
Bone morphogenetic proteins are multifunctional molecules having effects in many tissue types. They are members of the transforming growth factor-beta superfamily. At least 40 different types have been described to date. Their potential use in tissue regeneration has led to extensive research leading to a plethora of articles being published. This article provides a brief overview of the biological activity of different BMP's involved in the fracture healing process.
Matthews
S J E
SJ
The Oxford Trauma Unit, The John Radcliffe Hospital, Oxford OX3 9DU, UK. Stuart.Matthews@orh.nhs.uk
D019485:Bone Morphogenetic Proteins / Q000378:metabolism / Q000502:physiology* / Q000627:therapeutic use; D002454:Cell Differentiation; D020219:Chondrogenesis / Q000502:physiology; D017102:Fracture Healing / Q000187:drug effects*; D006801:Humans; D010011:Osteocytes / Q000166:cytology; D010012:Osteogenesis / Q000502:physiology
D019485:Bone Morphogenetic Proteins