title: Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms.
abstract: The objective of this experiment was to compare the effects of dietary mannan oligosaccharide (MOS) and a feed-grade antimicrobial (AM) on growth performance of nursery pigs reared on three different farms (A and B were large-scale commercial farms, and C was located at Michigan State University). On all farms, production was continuous flow by building, but all-in/all-out by room. Within each nursery facility, all pigs on the experiment were in one room. Pigs (Farm A, n = 771, weaning age = 18.4 d; Farm B, n = 576, weaning age = 19.0 d; Farm C, n = 96, weaning age = 20.6 d) were blocked (within farm) by BW and sex and allotted randomly to dietary treatments arranged in a 2 x 2 factorial. The two factors were 1) with and without MOS (0.3% in Phase I, 0.2% in Phases II, III, and IV; as-fed basis) and 2) with and without AM (110 mg of tylosin and 110 mg of sulfamethazine/kg of diet in all phases; as-fed basis). The four nursery phases were 4, 7, 14, and 17 d, respectively. With 35, 20, and 4 pigs per pen on Farms A, B, and C, respectively, space allowances per pig were 0.29, 0.26, and 0.56 m2. Across all farms, the addition of AM and MOS plus AM increased (P < 0.05) ADG (368, 406, and 410 g/d for control, AM, and MOS plus AM, respectively and increased ADFI (661, 703, and 710 g/d for control, AM, and MOS plus AM, respectively) for the entire 42-d experiment. The addition of MOS also increased ADG (P < 0.05) from d 0 to 42 of the experiment (394 g/d). Performance differed depending on farm (P < 0.01). Antimicrobial did not affect growth performance on Farm B, but it increased (P < 0.05) ADG on Farms A and C, ADFI on Farm A, and G:F on Farm C. Growth improvements with MOS on Farms A and B were not significant; however, pigs on Farm C fed MOS had greater (P < 0.05) ADG, ADFI, and G:F than controls. The results of this study suggest that MOS may be an alternative to tylosin and sulfa-methazine as a growth promotant in nursery diets.
authors.affiliation: Department of Animal Science, Michigan State University, East Lansing, 48854, USA. rozeboom@msu.edu
authors.forename: D W
authors.initials: DW
authors.lastname: Rozeboom
authors.forename: D T
authors.initials: DT
authors.lastname: Shaw
authors.forename: R J
authors.initials: RJ
authors.lastname: Tempelman
authors.forename: J C
authors.initials: JC
authors.lastname: Miguel
authors.forename: J E
authors.initials: JE
authors.lastname: Pettigrew
authors.forename: A
authors.initials: A
authors.lastname: Connolly
mesh_terms: D000383:Agriculture; D000821:Animal Feed; D000818:Animals; D000829:Animals, Domestic / Q000254:growth & development; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004032:Diet / Q000662:veterinary*; D019587:Dietary Supplements; D008351:Mannans / Q000494:pharmacology*; D013418:Sulfamethazine / Q000494:pharmacology*; D013552:Swine / Q000254:growth & development*; D013553:Swine Diseases / Q000517:prevention & control; D015645:Tylosin / Q000494:pharmacology*; D015430:Weight Gain / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D008351:Mannans; D013418:Sulfamethazine; D015645:Tylosin