A comparative study and development of an improved method for the reduction of nitroarenes into arylamines by Al/NH4X (X=Cl, Br, I) in methanol under ultrasonic conditions.
Nitroarenes were shown by us earlier to undergo reduction when treated with Al/NH4Cl in methanol under sonic conditions to give anilines in high yields [D. Nagaraja, M.A. Pasha, Tetrahedron Lett. 40 (1999) 7855]. Now, a comparative study has been carried out and an efficient and improved procedure for this reduction by using Al/NH4X (X=Cl, Br, I) is reported. A plausible mechanism of the reaction is envisaged.
Pasha
M A
MA
Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560 001, India. m_af_pasha@yahoo.co.in
Jayashankara
V P
VP
D000588:Amines / Q000138:chemical synthesis* / Q000528:radiation effects; D000432:Methanol / Q000737:chemistry* / Q000528:radiation effects; D017672:Nitrogen Compounds / Q000737:chemistry* / Q000528:radiation effects; D010084:Oxidation-Reduction / Q000528:radiation effects; D012996:Solutions; D013010:Sonication
D000588:Amines; D017672:Nitrogen Compounds; D012996:Solutions; D000432:Methanol