title: [Small cell carcinoma of the bladder: a case report].
abstract: A 61-year-old man was referred to our hospital with a complaint of gross hematuria and lower abdominal discomfort. Ultrasonography, magnetic resonance imaging and cystoscopy revealed a nodular invasive tumor in urinary bladder. The histopathological findings of transurethral-biopsy specimen was the small cell carcinoma and transitional cell carcinoma of the bladder infiltrating into smooth muscle layer. Total cystectomy with ileal conduit was performed following 1 course of neoadjuvant chemotherapy (M-VAC). Computed tomography (CT) before adjuvant chemotherapy revealed tiny lung metastasis in left peripheral lung area. As postoperative adjuvant therapy, 4 courses of chemotherapy (etoposide and calboplatin) were performed with 50 Gy of extra beam radiotherapy to the lung metastasis. Follow up CT revealed disapperance of lung metastasis, and the patient has been free from disease for one year after chemotherapy.
authors.affiliation: The Department of Urology, Fujisawa Municipal Hospital.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Hirai
authors.forename: Hutoshi
authors.initials: H
authors.lastname: Sano
authors.forename: Kaoru
authors.initials: K
authors.lastname: Kita
authors.forename: Kunihisa
authors.initials: K
authors.lastname: Mikata
authors.forename: Teiichiro
authors.initials: T
authors.lastname: Ueki
authors.forename: Naoya
authors.initials: N
authors.lastname: Fujikawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kitami
authors.forename: Shin
authors.initials: S
authors.lastname: Hirokawa
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D015653:Cystectomy; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D014547:Urinary Diversion
chemical_list: D005047:Etoposide; D016190:Carboplatin