title: [Two cases of advanced gastric cancer, successfully treated with TS-1/CDDP combination chemotherapy--case report].
abstract: We reported 2 cases with advanced gastric cancer, successfully treated with TS-1 and CDDP. Case 1 had Type 3 gastric cancer with left supra-clavicular (Virchow) and para-aortic lymph node metastases. Those distant node metastases completely disappeared after two courses of neoadjuvant chemotherapy (NAC) consisting of TS-1/ CDDP, and radical surgery for cure was conducted. The second case had Type 3 carcinoma with peritoneal dissemination. The primary lesion significantly decreased after four courses of the combination chemotherapy. The patient has been alive for 1 year and a half after 14 courses of TS-1/CDDP with stable disease. Significance of TS-1/CDDP in far advanced gastric cancer was discussed.
authors.affiliation: Dept. of Surgery, Yokohama City Kowan Hospital.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Ishihara
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Noguchi
authors.forename: Takaki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Kouhei
authors.initials: K
authors.lastname: Ando
authors.forename: Masako
authors.initials: M
authors.lastname: Shotsu
authors.forename: Naoki
authors.initials: N
authors.lastname: Ishiwa
authors.forename: Akira
authors.initials: A
authors.lastname: Takeda
authors.forename: Soichiro
authors.initials: S
authors.lastname: Morinaga
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Sachiko
authors.initials: S
authors.lastname: Yoshida
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ogoshi
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010094:Oxonic Acid / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000556:secondary; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin