title: Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine.
abstract: Alopecia areata (AA) is an autoimmune disease of uncertain pathogenesis, typically treated with immunomodulators. We report the paradoxical development of AA in two kidney-pancreas transplant recipients receiving immunosuppressive therapy, which included cyclosporine. Review of the literature revealed only 7 other cases of AA occurring in solid organ transplant recipients; all occurred during long-term cyclosporine therapy. The development of AA in this population highlights the complexity of this immunologic disease.
authors.affiliation: Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
authors.forename: Mariana Abraham
authors.initials: MA
authors.lastname: Phillips
authors.forename: Julie Elizabeth
authors.initials: JE
authors.lastname: Graves
authors.forename: Julia R
authors.initials: JR
authors.lastname: Nunley
mesh_terms: D000328:Adult; D000506:Alopecia Areata / Q000175:diagnosis / Q000276:immunology*; D016572:Cyclosporine / Q000627:therapeutic use; D003928:Diabetic Nephropathies / Q000601:surgery; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology*; D016035:Pancreas Transplantation / Q000276:immunology*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine