title: Effects of nutritional supplement with herbal extract on bone mineral density and height in prepubescent children - a preliminary study.
abstract: The aim of this study was to investigate the efficacy of a nutritional supplement with herbal extracts on height and on the bone mineral density (BMD) development of prepubescent children who were in the 25th percentile of standard height of their age. All children were administered a supplement for 6 months, with height and BMD measured. The supplement increased significantly the height and BMD, compared with the baseline in both boys and girls. The annual growth rate was higher than the standard rate. These preliminary data indicate that supplements enhanced the rate of BMD and height development, although this result must be replicated in a large population-based study and placebo-controlled trials to confirm the conclusions.
authors.affiliation: Center for Integrative Medicine, Institute of Medical Science, Wonkwang University, Iksan, Republic of Korea.
authors.forename: Myeong Soo
authors.initials: MS
authors.lastname: Lee
authors.forename: Ki-Won
authors.initials: KW
authors.lastname: Park
authors.forename: Ji-Sun
authors.initials: JS
authors.lastname: Park
authors.forename: Hye-Jung
authors.initials: HJ
authors.lastname: Kim
authors.forename: Sun-Rock
authors.initials: SR
authors.lastname: Moon
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D001827:Body Height / Q000187:drug effects; D015519:Bone Density / Q000187:drug effects; D001846:Bone Development / Q000187:drug effects; D001842:Bone and Bones / Q000187:drug effects*; D002136:Calcium, Dietary / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000187:drug effects; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal
chemical_list: D002136:Calcium, Dietary; D010936:Plant Extracts