title: Indications of penetrating keratoplasty in northern India.
abstract: OBJECTIVE
  To identify the indications for penetrating keratoplasty in northern India.
  
  
  METHODS
  All the eye bank records of penetrating keratoplasties performed during the period from June 1997 to November 2003 at Rajendra Prasad Center for Ophthalmic Sciences were reviewed.
  
  
  RESULTS
  During this period, 2022 penetrating keratoplasties were performed. The leading indications for penetrating keratoplasty were corneal scarring (38.03%) followed by acute infectious keratitis (28.38%), regrafting (11.5%), aphakic bullous keratopathy (7.27%), pseudophakic bullous keratopathy (6.18%), and corneal dystrophy (3.85%). Healed infectious keratitis (19.83%) was the most common subcategory among the eyes with corneal scarring followed by traumatic corneal scars (16.71%). Healed (19.83%) and active keratitis (28.38%) together accounted for the majority of keratoplasties (48.21%). In cataract-related corneal edema (13.45%), aphakic bullous keratopathy (7.27%) was almost as frequent as compared with pseudophakic bullous keratopathy (6.18%).
  
  
  CONCLUSIONS
  Corneal infections either active or healed are the most common indication for keratoplasty in northern India.
authors.affiliation: Cornea and Refractive Surgery Services, Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.
authors.forename: Parul
authors.initials: P
authors.lastname: Sony
authors.forename: Namrata
authors.initials: N
authors.lastname: Sharma
authors.forename: Seema
authors.initials: S
authors.lastname: Sen
authors.forename: Rasik B
authors.initials: RB
authors.lastname: Vajpayee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000453:epidemiology / Q000601:surgery*; D015818:Eye Infections, Bacterial / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies