Stereospecific change in conformation upon complexation of an exoditopic tetraamide host with a bis(ammonium) guest: chiral recognition and strong CD signaling.
Upon complexation of a rectangular-shaped achiral macrocyclic host with chiral guests, twisting deformation occurs to induce exciton-type bisignated CD, whereas a chiral rectangular host undergoes a similar structural change only with the matching enantiomer of a chiral guest.
Katoono
Ryo
R
Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.
Kawai
Hidetoshi
H
Fujiwara
Kenshu
K
Suzuki
Takanori
T
D000577:Amides / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D008968:Molecular Conformation; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
D000577:Amides; D000644:Quaternary Ammonium Compounds