title: [Cardiomyopathies. I: classification of cardiomyopathies--dilated cardiomyopathy].
abstract: Cardiomyopathies are common causes of heart failure and sudden cardiac death. According to the WHO classification, "specific" cardiomyopathies are differentiated from "idiopathic" cardiomyopathies. Thus, this classification is primarily based on pathophysiological characteristics. The diagnostic spectrum in cardiomyopathies comprises the entire spectrum of non-invasive and invasive cardiological examination techniques. The exact verification of certain cardiomyopathies necessitates additionally investigations. For example, immunohistological and molecular biological investigations of endomyocardial biopsies may confirm inflammatory cardiomyopathy, which is often induced by viruses. Several studies have shown that specific immunomodulatory treatment options can halt the progressive course of the disease. Several gene mutations have been identified in genetic/familial dilated cardiomyopathy. First-degree relatives should be screened for early stages. Primary prevention of sudden cardiac death shows increasing superiority of the implantable defibrillator compared with pharmacological approaches (i.e. amiodarone).
authors.affiliation: Medizinische Klinik II, Kardiologie und Pneumologie, Charité Universitätsmedizin Berlin. heinz-peter.schultheiss@charite.de
authors.forename: H P
authors.initials: HP
authors.lastname: Schultheiss
authors.forename: M
authors.initials: M
authors.lastname: Noutsias
authors.forename: U
authors.initials: U
authors.lastname: Kühl
authors.forename: D
authors.initials: D
authors.lastname: Lassner
authors.forename: U
authors.initials: U
authors.lastname: Gross
authors.forename: W
authors.initials: W
authors.lastname: Poller
authors.forename: M
authors.initials: M
authors.lastname: Pauschinger
mesh_terms: D009202:Cardiomyopathies / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D006333:Heart Failure / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'