title: Designed multiple ligands. An emerging drug discovery paradigm.
authors.affiliation: Medicinal Chemistry Department, Organon Laboratories, Newhouse, Lanarkshire, ML1 5SH, U.K. r.morphy@organon.co.uk
authors.forename: Richard
authors.initials: R
authors.lastname: Morphy
authors.forename: Zoran
authors.initials: Z
authors.lastname: Rankovic
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology; D000928:Antidepressive Agents / Q000737:chemistry / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000737:chemistry / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000737:chemistry / Q000494:pharmacology; D002626:Chemistry, Pharmaceutical / Q000639:trends*; D065127:Dopamine D2 Receptor Antagonists; D015195:Drug Design; D006801:Humans; D008024:Ligands; D008659:Metabolic Diseases / Q000188:drug therapy; D047492:Peroxisome Proliferator-Activated Receptors / Q000187:drug effects; D011969:Receptors, Histamine H1 / Q000187:drug effects; D017367:Selective Serotonin Reuptake Inhibitors / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D018926:Anti-Allergic Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000928:Antidepressive Agents; D000959:Antihypertensive Agents; D014150:Antipsychotic Agents; D065127:Dopamine D2 Receptor Antagonists; D008024:Ligands; D047492:Peroxisome Proliferator-Activated Receptors; D011969:Receptors, Histamine H1; D017367:Selective Serotonin Reuptake Inhibitors