title: Electrospray ionization mass spectrometry study on dipeptide 4-chlorobutyl ester produced from refluxing of amino acid with phosphoryl chloride in tetrahydrofuran.
abstract: Phosphoryl chloride was able to promote the formation of peptide and the ringopening of tetrahydrofuran (THF) followed by a sequence of successive reactions by simply refluxing. ESI multistage tandem mass spectrometry was applied to trace the reaction and elucidate the product structures, dipeptide 4-chlorobutyl ester.
authors.affiliation: Department of Chemistry and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, 361005, P.R. China.
authors.forename: Gui Ji
authors.initials: GJ
authors.lastname: Zhou
authors.forename: Ze
authors.initials: Z
authors.lastname: Liu
authors.forename: Tong Jian
authors.initials: TJ
authors.lastname: Wang
authors.forename: Peng Xiang
authors.initials: PX
authors.lastname: Xu
authors.forename: Gou
authors.initials: G
authors.lastname: Tang
authors.forename: Yong
authors.initials: Y
authors.lastname: Ye
authors.forename: Yu Fen
authors.initials: YF
authors.lastname: Zhao
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D004151:Dipeptides / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D017553:Phosphorus Compounds / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D000596:Amino Acids; D004151:Dipeptides; D005663:Furans; D017553:Phosphorus Compounds; D012997:Solvents; C018674:tetrahydrofuran; C013196:phosphoryl chloride