title: Transvaginal mesh technique for pelvic organ prolapse repair: mesh exposure management and risk factors.
abstract: Prosthetic reinforcement in the surgical repair of pelvic prolapse by the vaginal approach is not devoid of tolerability-related problems such as vaginal erosion. The purposes of our study are to define the risk factors for exposure of the mesh material, to describe advances and to recommend a therapeutic strategy. Two hundred and seventy-seven patients undergoing surgery due to pelvic prolapse with transvaginal mesh technique were included in a continuous, retrospective study between January 2002 and December 2003. Thirty-four cases of mesh exposure were observed within the 2 months following surgery, which represents an incidence of 12.27%. All the patients were medically treated, nine of whom were found to have completely healed during the check-up performed at 2 months. In contrast, 25 patients required partial mesh exeresis. Risk factors of erosion were concomitant hysterectomy [OR = 5.17 (p = 10(-3))] and inverted T colpotomy [OR = 6.06 (p = 10(-2))]. Two technical guidelines can be defined from this study as regards the surgical procedure required in order to limit mesh exposure via the vaginal route. The uterus must be preserved, and the number and extent of colpotomies needed to insert the mesh must be limited.
authors.affiliation: Hôpital Jeanne de Flandre, Clinique de Gynécologie, Obstétrique et Néonatalogie, Centre Hospitalier Régional Universitaire de Lille, 2 Avenue Oscar Lambret, 59037, Lille Cedex, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Collinet
authors.forename: Franck
authors.initials: F
authors.lastname: Belot
authors.forename: Philippe
authors.initials: P
authors.lastname: Debodinance
authors.forename: Edouard
authors.initials: E
authors.lastname: Ha Duc
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Lucot
authors.forename: Michel
authors.initials: M
authors.lastname: Cosson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020884:Colpotomy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects; D008875:Middle Aged; D017773:Pelvic Floor / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors; D013526:Surgical Mesh / Q000009:adverse effects* / Q000592:standards; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000473:pathology / Q000601:surgery*