SYCP3 mutations are uncommon in patients with azoospermia.
Mutation analysis of the SYCP3 gene was performed for 58 patients with a maturation arrest of spermatogenesis. In contrast to the previously reported high frequency of mutations, only polymorphisms were found in the present study.
Stouffs
Katrien
K
Research Center for Reproduction and Genetics, Vrije Universiteit Brussel, Laarbeeklaan, Brussels, Belgium. katrien.stouffs@az.vub.ac.be
Lissens
Willy
W
Tournaye
Herman
H
Van Steirteghem
André
A
Liebaers
Inge
I
D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D009845:Oligospermia / Q000235:genetics*
D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; C490060:SYCP3 protein, human