Polymorphous adenocarcinoma of the breast. Report of three cases.
We report three cases of polymorphous adenocarcinoma (PLA) of the breast in 37-, 55- and 74-year-old women, respectively. The patients have no evidence of previous malignancy. The tumours consist of monotonous cells showing a wide spectrum of growth patterns: solid nests, trabeculae, tubules, cribriform structures, strands and fascicles reminiscent of polymorphous low-grade adenocarcinoma of salivary glands. To our knowledge, PLA has never been reported in the breast; therefore, this tumour should be added to the list of neoplastic lesions of the breasts that have the same features as those of the salivary glands.
Asioli
Sofia
S
Section of Pathology, Department of Oncology, University of Bologna, Bellaria Hospital, Bologna, Italy.
Marucci
Gianluca
G
Ficarra
Guido
G
Stephens
Mark
M
Foschini
Maria P
MP
Ellis
Ian O
IO
Eusebi
Vincenzo
V
D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000473:pathology