Disseminated Sporothix schenckii in a patient with AIDS.
Sporothrix schenckii is a widespread dimorphic fungus which can cause cutaneous infection following local implantation. Disseminated sporotrichosis may occur in immunodeficient individuals but meningitis remains a rare complication. Diagnosis is usually difficult, requiring isolation of the organism from the CSF or skin so appropriate treatment can be promptly initiated. We present the first case of S. schenckii meningitis reported in the UK in a patient with AIDS. He presented with insidious features of meningoencephalitis, hydrocephalus and multiple cutaneous lesions and failed to respond to therapy.
Hardman
S
S
Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK. susanhardman@hotmail.com
Stephenson
I
I
Jenkins
D R
DR
Wiselka
M J
MJ
Johnson
E M
EM
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D003881:Dermatomycoses / Q000382:microbiology*; D017809:Fatal Outcome; D015658:HIV Infections / Q000150:complications; D015497:HIV-1; D006801:Humans; D008297:Male; D016921:Meningitis, Fungal / Q000382:microbiology*; D013175:Sporothrix / Q000302:isolation & purification*; D013174:Sporotrichosis / Q000382:microbiology*