Periocular mucosa-associated lymphoid/low grade lymphomas: treatment with antibiotics.
OBJECTIVE
To report on the treatment of primary mucosa-associated lymphoid tumors (MALT)/low grade lymphomas of the conjunctiva/orbit treated solely with systemic antibiotics.


METHODS
Retrospective interventional case series.


METHODS
Three adult patients with biopsy/marker proven MALT lymphomas of the conjunctiva/orbit were treated with systemic antibiotics and followed for signs of local or systemic relapse.


RESULTS
All three patients showed a response to antibiotics based on clinical, ultrasonographic, and MRI/CT imaging studies. Two patients have had complete remissions (42 months follow-up) and one a partial remission (18 months). No systemic relapses have occurred.


CONCLUSIONS
MALT/low grade lymphomas of the conjunctiva/orbit respond to systemic antibiotic therapy and may have complete remissions.
Abramson
David H
DH
Ophthalmic Oncology Service, Department Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. abramsod@mskcc.org
Rollins
Indira
I
Coleman
Morton
M
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003230:Conjunctival Neoplasms / Q000188:drug therapy* / Q000382:microbiology; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy* / Q000382:microbiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000188:drug therapy* / Q000382:microbiology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D004318:Doxycycline