title: Ovarian imaging by magnetic resonance in obese adolescent girls with polycystic ovary syndrome: a pilot study.
abstract: OBJECTIVE
  To determine whether magnetic resonance (MR) imaging can serve as a useful investigational tool in the assessment of the polycystic ovary as compared with transabdominal ultrasound (US) for obese adolescents with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Tertiary university hospital.
  
  
  METHODS
  Eleven obese adolescents with PCOS.
  
  
  METHODS
  Pelvic MR and US imaging and blood sampling.
  
  
  METHODS
  Total ovarian volume and follicle count; mean follicle count per longitudinal cross-section; stromal area; biochemical correlations with measured ovarian parameters.
  
  
  RESULTS
  With MR, the mean (+/-SE) total follicle count (21.9 +/- 1.3) was significantly greater than that observed with US (5.5 +/- 1.7) and significantly correlated with total ovarian volume. Two-dimensional cross-sectional analysis of the ovary by MR revealed a significantly greater mean follicle count (12.1 +/- 0.8) compared with the results obtained by US (3.0 +/- 0.5). The stromal area (173.3 +/- 25.1 mm2) was approximately 35% of the total ovarian surface area. No correlations were observed between biochemical indices and measured ovarian parameters.
  
  
  CONCLUSIONS
  In contrast to US, MR provides vastly greater delineation of the structural components of the ovary in obese girls with PCOS and thus can serve as an excellent investigational technique to assess the morphological transformation of the adolescent ovary.
authors.affiliation: Department of Reproductive Endocrinology and Infertility, University of California at San Diego, La Jolla, California 92093-0633, USA.
authors.forename: Richard Y
authors.initials: RY
authors.lastname: Yoo
authors.forename: Claude B
authors.initials: CB
authors.lastname: Sirlin
authors.forename: Michael
authors.initials: M
authors.lastname: Gottschalk
authors.forename: R Jeffrey
authors.initials: RJ
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009765:Obesity / Q000097:blood / Q000473:pathology*; D010053:Ovary / Q000378:metabolism / Q000473:pathology*; D010865:Pilot Projects; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000473:pathology*; D011446:Prospective Studies