title: Expanding organoboron chemistry: epoxidation of potassium organotrifluoroborates.
abstract: Most organoboron reagents are highly susceptible to oxidation by a variety of oxidants. In these processes, the valuable carbon-boron bond is cleaved. The organotrifluoroborates examined in this contribution appear resistant to many common oxidants. Consequently, thioether-substituted alkyltrifluoroborates can be oxidized to the corresponding sulfones, while retaining the trifluoroborate moiety. 1-Trifluoroboratoalkenes are oxidized by dioxirane, providing air-stable, crystalline oxiranyltrifluoroborates. These interesting materials are structurally analogous to oxiranyl anions, unstable intermediates that would otherwise be of tremendous synthetic utility. Finally, the first Suzuki-Miyaura coupling of an epoxytrifluoroborate has been accomplished. The chemistry described begins to expand organoboron chemistry in significant new directions.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry. University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA. gmolandr@sas.upenn.edu
authors.forename: Gary A
authors.initials: GA
authors.lastname: Molander
authors.forename: María
authors.initials: M
authors.lastname: Ribagorda