[Effect of fezam on ocular dynamics in patients with senile macular degeneration].
The complex treatment in 25 patients with non-exudative forms of senile macular degeneration (ARMD) included the use of the nootropic agent fezam. Better visual acuity after a course of therapy was noted in 76% of the eyes of patients with ARMD. Color Doppler mapping prior to treatment indicated that all the patients had a significant reduction in the maximum systolic and end-diastolic blood flow velocities (Vs and Vd, respectively), and the increased peripheral resistance index (RI) in the ophthalmic artery, central artery of the retina, and short posterior ciliary arteries as compared to the normal values. Higher ophthalmic arterial blood flow velocities after a course of therapy are indicative of better blood supply to the tunics of the eye, which is a favorable sign for the prognosis of the disease. The use of fezam is effective in the complex therapy of non-exudative forms of senile macular degeneration.
Kiseleva
T N
TN
Lagutina
Iu M
IuM
Kravchuk
E A
EA
D002936:Cinnarizine / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D004338:Drug Combinations; D005123:Eye / Q000098:blood supply / Q000187:drug effects*; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010889:Piracetam / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D011379:Prognosis; D013997:Time Factors; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D014792:Visual Acuity / Q000187:drug effects*
D004338:Drug Combinations; C500648:phezam; D002936:Cinnarizine; D010889:Piracetam