title: Primary lymphomas of bone.
abstract: Primary bone lymphoma is rare. The majority of cases are diffuse large B-cell non-Hodgkin's lymphomas. Classification, staging, and treatment are controversial. The relatively small number of cases has led to many case reports and series describing institutional experiences but precludes the use of randomized clinical trials to address the question of optimal management. This article will review clinical and radiologic presentations, diagnostic techniques, and histologic characteristics. Most important, it will present what limited information we do have regarding effective treatment options for this unusual type of lymphoma.
authors.affiliation: Division of Hematology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: Paula
authors.initials: P
authors.lastname: Gill
authors.forename: Doris E
authors.initials: DE
authors.lastname: Wenger
authors.forename: David J
authors.initials: DJ
authors.lastname: Inwards
mesh_terms: D005266:Femoral Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D011859:Radiography; D016032:Randomized Controlled Trials as Topic