title: [Short-term effect of paclitaxel-eluting stent in the treatment of coronary heart disease due to coronary arteriosclerosis].
abstract: OBJECTIVE
  To evaluate the short-term safety and efficacy of paclitaxel-eluting stent (TAXUS stent, Boston Scientific) in the treatment of coronary heart disease (CHD) due to coronary arteriosclerosis.
  
  
  METHODS
  From July 2003 to November 2004, 300 consecutive patients with CHD due to coronary arteriosclerosis were admitted for selective percutaneous coronary intervention (PCI) and paclitaxel-eluting stent implantation in the coronary arteries. The immediate effects after PCI and follow-up results were investigated.
  
  
  RESULTS
  Altogether 350 lesions were treated and 355 paclitaxel-eluting stents implanted in the 300 cases. Of these lesions, 248 (70.9%) was complicated lesions of B2 type or worse, 94 (26.5%) small-caliber stents (2.50-2.75 mm) and 130 (36.6%) long stents (>20 mm) were implanted, without occurrence of severe intra-operative complications. Follow-up study of 250 cases (83.3%) lasting for 1 to 15 months was conducted, and chest pain was reported in 8 cases, 2 of which underwent coronary artery angiography and no in-stent restenosis was found. One patient developed myocardial infarction 5 months after PCI, and 2 died for non-cardiogenic factors.
  
  
  CONCLUSIONS
  Paclitaxel-eluting stent implantation in patients undergoing PCI is safe approach with good short-term efficacy.
authors.affiliation: Department of Cardiology, Wuhan Asia Heart Disease Hospital, Wuhan 430022, China.
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Wan
authors.forename: Guo-ying
authors.initials: GY
authors.lastname: Zhu
authors.forename: Ren-peng
authors.initials: RP
authors.lastname: Wang
authors.forename: Xi
authors.initials: X
authors.lastname: Su
authors.forename: Jian
authors.initials: J
authors.lastname: Peng
authors.forename: Dan
authors.initials: D
authors.lastname: Song
authors.forename: Guo-hong
authors.initials: GH
authors.lastname: Chen
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D015607:Stents
chemical_list: D017239:Paclitaxel