[Progress in phthalate ester toxicity in the female reproductive system].
Phthalates are high-production-volume synthetic chemicals with ubiquitous environmental pollution because of their use in plastics and other common consumer products. Epidemiological evidence suggests the relation between women-exposure and the potential health hazards of Phthalates. Here we review research about how phthalates interact with the female reproductive system in vivo, in vitro models, embryo development toxicity and the mechanisms of female toxicity.
Zhang
Jian-Jiang
JJ
Department of Environment Hygiene, Third Military Medical University, Chongqing 400038, China.
Shu
Wei-Qun
WQ
D000818:Animals; D004051:Diethylhexyl Phthalate / Q000633:toxicity*; D004785:Environmental Pollutants / Q000633:toxicity*; D004958:Estradiol / Q000097:blood; D004971:Estrus / Q000187:drug effects; D005260:Female; D006801:Humans; D010053:Ovary / Q000187:drug effects* / Q000473:pathology; D010060:Ovulation / Q000187:drug effects
D004785:Environmental Pollutants; D004958:Estradiol; D004051:Diethylhexyl Phthalate