[A particular hepatocellular carcinoma combining the ordinary and the fibrolamellar variant].
Fibrolamellar carcinoma (FLC) of the liver is a rare variant of hepatocellular carcinoma (HCC) occurring on non cirrhotic liver. Since its first description by Hugh Edmondson in 1956, 200 cases of FLC have been reported in the literature, but only some cases describe the association of the ordinary HCC with the FLC within the same lesion. We report in this study the case of a 14-year-old female patient with a hepatic mass whose radiological aspect evoked a nodular and focal hyperplasia. Histologically, this tumor was composed of area of FLC mixed with ordinary HCC. Staining for cytokeratine 7 was positive in the FL component and negative in the ordinary HCC component.
Zermani
Rachida
R
Service d'anatomie et de cytologie pathologique, Hôpital Charles Nicolle, Tunis, Tunisie.
Charfi
Lamia
L
Kourda
Nadia
N
Farah
Faten
F
Rammeh
Soumaya
S
Trabelsi
Omar
O
Zaouch
Abdejlil
A
Ben Jilani
Sarra
S
D000293:Adolescent; D006528:Carcinoma, Hepatocellular / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D053552:Keratin-7; D007633:Keratins / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*
C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins