Neural correlates of symbolic number processing in children and adults.
Using functional magnetic resonance imaging, we examined developmental differences in the functional neuroanatomy underlying symbolic number processing. Twelve adults and 12 children had to judge the relative magnitude of two single-digit Arabic numerals. We investigated which brain areas were significantly (P<0.005, uncorrected) more activated during processing of number pairs with small relative to large numerical distances. In the adult group, symbolic distance modulated bilateral parietal regions. In contrast, the group of children primarily engaged frontal regions. We conclude that the functional neuroanatomy underlying symbolic numerical magnitude processing undergoes an ontogenetic shift towards greater parietal engagement. This change may reflect maturation of underlying representations and increasing automaticity in mapping between numerical symbols and the magnitudes they represent.
Ansari
Daniel
D
Numerical Cognition Laboratory, Department of Education, Dartmouth College, Hanover, New Hampshire 03755, USA. Daniel.Ansari@Dartmouth.Edu
Garcia
Nicolas
N
Lucas
Elizabeth
E
Hamon
Kathleen
K
Dhital
Bibek
B
D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D001921:Brain / Q000033:anatomy & histology / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D002648:Child; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008433:Mathematics; D008606:Mental Processes / Q000502:physiology*; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D013997:Time Factors
D010100:Oxygen