title: [The farmost unknown disease of postoperative permanent hypoparathyroidism--feasibility and validation of an innovative questionnaire instrument].
abstract: Aim of our study has been the systematic evaluation concerning the still farmost unknown disease of postoperative, permanent hypoparathyroidism. For this we designed a specific questionnaire as measuring instrument--it was evaluated by experts and validated by 3 control groups--to examine then a patient group (n = 20) with symptomatic postoperative, permanent hypoparathyroidism. The application of the questionnaire was very feasible, the reliability of measuring scales according to Cronbach's alpha > or = 0.70. The validity of content and construct validity fully existed (Pearson's correlation coefficient r > or = - 0.27; p < 0,05). The farmost frequent clinical complaints were peripheral cold sensations (65 %), pains in joints (55 %), sensation of heaviness and weakness in extremities (55 %) and paresthesias (45 %). Most frequent clinical symptoms were brittle nails (40 %) and diarrhoea (35 %). Sum and distress level scores for classification of illness severity were determined. In conclusion our questionnaire is a valid instrument and from a clinical point of view easy to apply, reasonable and very feasible in practical use. It represents a novel, optimum instrument to determine disease condition and illness severity of hypoparathyroid patients and makes it possible to gain further information of this up to now less systematically analysed disease.
authors.affiliation: Klinik und Poliklinik für Herz- und Thoraxchirurgie, Julius-Maximilians-Universität Würzburg, Deutschland. bohrer_t_htc@klinik.uni-wuerzburg.de
authors.forename: T
authors.initials: T
authors.lastname: Bohrer
authors.forename: P
authors.initials: P
authors.lastname: Fleischmann
authors.forename: A
authors.initials: A
authors.lastname: Tersteegen
authors.forename: C
authors.initials: C
authors.lastname: Hasse
mesh_terms: D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000175:diagnosis / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D016105:Parathyroidectomy; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000175:diagnosis / Q000523:psychology*; D011594:Psychometrics / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012803:Sick Role; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D013965:Thyroidectomy