Orbital peripheral T-cell lymphoma in a child.
A 6-year-old boy with known peripheral T-cell lymphoma had progressive left periorbital swelling and CT findings consistent with abscess or necrosis. Biopsy revealed peripheral T-cell lymphoma and associated necrosis involving the lacrimal gland and surrounding orbital tissue. Immunohistochemical and T-cell receptor gene rearrangement studies confirmed the diagnosis. The patient responded to local radiation and systemic chemotherapy. This is the first pathologically confirmed case of orbital peripheral T-cell lymphoma with subpanniculitic features.
Hassan
Adam S
AS
Department of Ophthalmology, University of Michigan, Ann Arbor, Michigan 48105, USA.
Elner
Victor M
VM
D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D002648:Child; D003131:Combined Modality Therapy; D015329:Gene Rearrangement, T-Lymphocyte / Q000235:genetics; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000235:genetics; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D014408:Biomarkers, Tumor; D016692:Receptors, Antigen, T-Cell, gamma-delta; D014747:Vinblastine