title: Acute nicotine withdrawal symptoms and anxious responding to bodily sensations: a test of incremental predictive validity among young adult regular smokers.
abstract: Although previous work has found associations between panic and smoking, little research has investigated potential mechanisms by which smoking may contribute to panic problems. The present investigation evaluated the incremental validity of acute nicotine withdrawal symptoms (elicited by an average of 2h of nicotine deprivation) relative to negative affectivity, anxiety sensitivity, and nicotine dependence in predicting anxiety responding to 3-min voluntary hyperventilation. The sample consisted of 90 regular smokers (46 females), as defined by smoking >or= 10 cigarettes per day for at least 1 year, recruited through the general community. Consistent with prediction, greater levels of pre-challenge nicotine withdrawal symptoms uniquely predicted post-challenge intensity of panic symptoms and anxiety relative to other established factors. Findings are discussed in the context of how regular smoking may promote panic symptomotology.
authors.affiliation: Department of Psychology, University of Vermont, 320 Dewey Hall, Burlington, VT 05405, USA. michael.zvolensky@uvm.edu
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Zvolensky
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Feldner
authors.forename: Ellen W
authors.initials: EW
authors.lastname: Leen-Feldner
authors.forename: Laura E
authors.initials: LE
authors.lastname: Gibson
authors.forename: Kenneth
authors.initials: K
authors.lastname: Abrams
authors.forename: Kristin
authors.initials: K
authors.lastname: Gregor
mesh_terms: D000328:Adult; D001007:Anxiety / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009538:Nicotine; D016584:Panic Disorder / Q000175:diagnosis / Q000209:etiology; D011446:Prospective Studies; D011581:Psychological Tests; D016540:Smoking Cessation; D013375:Substance Withdrawal Syndrome / Q000523:psychology*
chemical_list: D009538:Nicotine