Successful sperm storage for 28 years.
OBJECTIVE
To report on two instances of successful long-term cryopreservation resulting in live births.


METHODS
Case report.


METHODS
The patient stored his sperm at a private sperm banking facility, and his partner underwent artificial insemination at an obstetrics/gynecology practice for one pregnancy and at a fertility center for the other.


METHODS
One man who stored his sperm before treatment for cancer.


METHODS
Storage of sperm under liquid nitrogen in a carousel canister system. Intrauterine insemination in which the semen was thawed, washed with human tubal fluid (HTF), and inseminated.


METHODS
Successful pregnancy resulting in live birth.


RESULTS
Artificial insemination with semen cryopreserved for 21 and 28 years resulted in two live births.


CONCLUSIONS
This case report describes the to-date longest known successful cryopreservation of sperm, with two live births resulting from IUI. Successful long-term semen storage can be very beneficial for men facing impaired fertility or sterility early in life, so that they have sufficient time to make appropriate family planning decisions.
Feldschuh
Joseph
J
Idant Laboratories, New York, New York, USA. jfeldschuh@daxor.com
Brassel
James
J
Durso
Nancy
N
Levine
Allen
A
D000328:Adult; D015925:Cryopreservation / Q000379:methods*; D005260:Female; D006801:Humans; D050498:Live Birth; D008297:Male; D008875:Middle Aged; D012662:Semen Preservation / Q000379:methods*; D013094:Spermatozoa / Q000166:cytology / Q000502:physiology*