Stannyl cyclopropanes by diastereoselective cyclopropanations with (tributylstannyl)-diazoacetate esters catalyzed by Cu(I) N-heterocyclic carbene.
Catalyzed cyclopropanations of alkenes with Bu3SnC(=N2)CO2R (R = Et, t-Bu) have been achieved in good yield with excellent diastereoselectivity to make stannyl cyclopropanes having two or three stereocenters, one of which is quaternary.
Gawley
Robert E
RE
Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA. bgawley@uark.edu
Narayan
Sanjay
S