title: A case of Reye syndrome with rotavirus infection accompanied with high cytokines.
abstract: We report on a 23-month-old boy with a rare complication of rotavirus gastroenteritis. He was diagnosed as acute encephalopathy with DIC accompanied with high levels of cytokines. The liver pathology also revealed mild infiltration and fatty changes. He was suspected to be suffering from a cytokine storm followed by Reye syndrome.
authors.affiliation: Department of Paediatrics, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ioi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kawashima
authors.forename: Shigeo
authors.initials: S
authors.lastname: Nishimata
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Gaku
authors.initials: G
authors.lastname: Yamanaka
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Kashiwagi
authors.forename: Naoto
authors.initials: N
authors.lastname: Yamada
authors.forename: Kazumitsu
authors.initials: K
authors.lastname: Tsuyuki
authors.forename: Kouji
authors.initials: K
authors.lastname: Takekuma
authors.forename: Akinori
authors.initials: A
authors.lastname: Hoshika
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kage
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D001707:Biopsy, Needle; D016207:Cytokines / Q000097:blood*; D003937:Diagnosis, Differential; D005759:Gastroenteritis / Q000150:complications* / Q000175:diagnosis / Q000821:virology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007223:Infant; D008099:Liver / Q000473:pathology; D008297:Male; D008874:Midazolam / Q000627:therapeutic use; D008928:Mitochondria / Q000473:pathology; D012121:Respiration, Artificial; D012202:Reye Syndrome / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D012400:Rotavirus Infections / Q000150:complications* / Q000175:diagnosis; D013874:Thiopental / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000927:Anticonvulsants; D016207:Cytokines; D006993:Hypnotics and Sedatives; D013874:Thiopental; D008874:Midazolam