title: Changes in hemodynamic and post-flights orthostatic tolerance of cosmonauts under application of the preventive device--thigh cuffs bracelets in short-term flights.
abstract: to evaluate the influence of the use thigh cuffs "Bracelet" on the hemodynamic adaptation to microgravity during short-term (up to a month) space flights, in-flight tolerance to LBNP-tests and post-flight orthostatic tolerance. 6 cosmonauts applied and 7 others did not apply the occlusive cuffs when on flight. The "Bracelet" device notably relieved the cosmonauts from the subjective discomfort following by the blood redistribution at initial period of exposure to microgravity. It was established that "Bracelet" lessened shifts in central and peripheral hemodynamics typical for exposure to microgravity, venous stasis in the cervical-cephalic region in particular. There were no differences between the hemodynamic reaction on LBNP-test in cosmonauts who applied and not applied "Bracelet" during short-term flights. The objective data are received, that the application of the device during short-term space flight does not make negative effects on post-flight orthostatic tolerance.
authors.affiliation: RF State Scientific Center-Institute for Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia.
authors.forename: G
authors.initials: G
authors.lastname: Fomina
authors.forename: A
authors.initials: A
authors.lastname: Kotovskaya
authors.forename: F
authors.initials: F
authors.lastname: Arbeille
authors.forename: V
authors.initials: V
authors.lastname: Pochuev
authors.forename: A
authors.initials: A
authors.lastname: Zhernavkov
authors.forename: T
authors.initials: T
authors.lastname: Ivanovskaya
mesh_terms: D000222:Adaptation, Physiological; D000337:Aerospace Medicine; D018480:Astronauts; D002560:Cerebrovascular Circulation / Q000502:physiology; D005268:Femoral Vein / Q000502:physiology; D018495:Fluid Shifts / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology / Q000517:prevention & control*; D008150:Lower Body Negative Pressure; D013026:Space Flight; D019442:Space Suits; D013997:Time Factors; D014893:Weightlessness