title: Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.
abstract: Capecitabine is used to treat advanced breast and gastrointestinal malignancies. A single case of encephalopathy and three cases of peripheral neuropathy are the only neurotoxicities reported. The authors report five additional cases of capecitabine-induced multifocal leukoencephalopathy.
authors.affiliation: Davee Department of Neurology and Neurological Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
authors.forename: A
authors.initials: A
authors.lastname: Videnovic
authors.forename: I
authors.initials: I
authors.lastname: Semenov
authors.forename: R
authors.initials: R
authors.lastname: Chua-Adajar
authors.forename: L
authors.initials: L
authors.lastname: Baddi
authors.forename: D T
authors.initials: DT
authors.lastname: Blumenthal
authors.forename: A C
authors.initials: AC
authors.lastname: Beck
authors.forename: T
authors.initials: T
authors.lastname: Simuni
authors.forename: S
authors.initials: S
authors.lastname: Futterer
authors.forename: W
authors.initials: W
authors.lastname: Gradishar
authors.forename: C
authors.initials: C
authors.lastname: Tellez
authors.forename: J J
authors.initials: JJ
authors.lastname: Raizer
mesh_terms: D000328:Adult; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects* / Q000473:pathology* / Q000503:physiopathology; D001943:Breast Neoplasms / Q000188:drug therapy; D000069287:Capecitabine; D002277:Carcinoma / Q000188:drug therapy; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000188:drug therapy; D020258:Neurotoxicity Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D010190:Pancreatic Neoplasms / Q000188:drug therapy; D028761:Withholding Treatment
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil