Fine structure and mineral components of fibrous stonelike masses obtained from the human mesenteries.
We investigated the fine structure and mineral components of 29 stonelike masses obtained from the mesenteries of four adult cadavers, using optical microscopy, backscattered electron imaging, scanning electron microscopy, energy-dispersive X-ray microanalysis, and X-ray diffraction. Although the overall appearance of the stonelike masses measuring about 5-20 mm in diameter and 0.06-3.1 g in dry weight was roughly grouped into smooth bulb- and uneven bulk-shaped types, all the calcified masses basically consisted of core and mantle regions. The smooth bulb-shaped masses had a broad mantle with many concentric rings, whereas the uneven bulk-shaped masses contained a large core. In their core regions, spherulitic and short bundle-shaped deposits composed of needle-shaped apatite crystals were mainly found among loose collagen fibers. Their mantle regions, on the other hand, showed the concentric structures of dense collagen fibers in the intra- and/or extrafibrous calcification with fine sandy grain-shaped deposits. The mineral elements were mainly Ca and P, and the major crystals were hydroxyapatite. Hexahedral whitlockite containing Mg was a minor component. The fiber-rich mantle regions showed lower calcification and lesser crystallization than the fiber-poor core region. When necrotic or some tumor adipose tissues and necrotic lymphoid tissues that might have been caused by some digestive diseases are recognized as foreign matter, their tissues occasionally will be calcified and grow into stonelike masses. These stonelike masses tend to occur more often in women than in men.
Kodaka
Tetsuo
T
Department of Oral Histology, Showa University School of Dentistry, Shinagawa-ku, Tokyo 142-8555, Japan. kodaka@dent.showa-u.ac.jp
Mori
Ryoichi
R
Hirayama
Akihiko
A
Sano
Tsuneyoshi
T
D002113:Calcification, Physiologic; D003460:Crystallization; D004577:Electron Probe Microanalysis; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry; D008638:Mesenteric Arteries / Q000737:chemistry / Q000648:ultrastructure*; D008903:Minerals / Q000032:analysis*; D014961:X-Ray Diffraction
D006882:Hydroxyapatites; D008903:Minerals