Wilson disease with an initial manifestation of polyneuropathy.
BACKGROUND
Recognition of Wilson disease (WD) is sometimes difficult because of its diverse manifestations. Peripheral neuropathy is rarely reported in the context of WD.


OBJECTIVE
To report an unusual patient with WD whose initial manifestation was peripheral neuropathy.


METHODS
Case report.


METHODS
Neurology department in a tertiary referral center.


METHODS
Personal observation.


RESULTS
A 17-year-old man, who was eventually diagnosed with WD, was initially seen with polyneuropathy at least 6 months prior to developing more typical symptoms of WD. Electrophysiological and pathological studies suggested a neuropathy of mixed type. Treatment for WD resulted in clinical and electrophysiological improvement.


CONCLUSIONS
Wilson disease may initially appear as a treatable polyneuropathy.
Jung
Keun-Hwa
KH
Department of Neurology and Clinical Research Institute, Seoul National University Hospital, Kyung Hee University Hospital, Seoul, South Korea.
Ahn
Tae-Beom
TB
Jeon
Beom S
BS
D000293:Adolescent; D001921:Brain / Q000473:pathology; D004594:Electrophysiology; D006527:Hepatolenticular Degeneration / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011115:Polyneuropathies / Q000209:etiology* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology