title: Optical coherence tomography findings in tamoxifen retinopathy.
abstract: OBJECTIVE
  To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy.
  
  
  METHODS
  Observational cases report.
  
  
  METHODS
  Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3.
  
  
  RESULTS
  Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening.
  
  
  CONCLUSIONS
  In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a foveolar cystoid space different from macular edema.
authors.affiliation: Department of Ophthalmology, Hôpital Lariboisiĕre, Assistance Publique-Hôpitaux de Paris, Université Paris #7, Paris, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Gualino
authors.forename: Salomon Y
authors.initials: SY
authors.lastname: Cohen
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: Delyfer
authors.forename: José-Alain
authors.initials: JA
authors.lastname: Sahel
authors.forename: Alain
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008875:Middle Aged; D012160:Retina / Q000187:drug effects / Q000473:pathology*; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D013629:Tamoxifen / Q000009:adverse effects*; D041623:Tomography, Optical Coherence
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen