Lipid peroxidation and the system of antioxidant defence in humans after hypergravitational influence.
Hypergravitational influence (HI) +Gz (head-pelvis) within ranges of up to 3, up to 5, and up to 7 g with an acceleration speed of 0.03 g/s was applied to a group of men of an age of 25 to 45 y.o. In their blood serum the parameters of lipid peroxidation (LP) and the system of antioxidant defence (AOD) had been studied. HI results in LP intensity changing in a human body. HI increasing caused an increase in a number of AOD components involved in the free radical processes (FRP) compensation and functioning in a water phase. The characteristics of AOD lipid-phase link does not change. The mechanisms of compensating and monitoring of FRP intensity at HI required further studies.
Markin
Andrei
A
State Scientific Center of Russian Federation Institute for Biomedical Problems Russian Academy of Sciences, Moscow, Russia. markine@mail.cnt.ru
Juravlyova
Olga
O
Lukianuk
Vasily
V
D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D018471:Hypergravity; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008875:Middle Aged; D013026:Space Flight; D013312:Stress, Physiological; D013997:Time Factors; D024505:Tocopherols / Q000378:metabolism
D000975:Antioxidants; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D024505:Tocopherols