title: A novel one-pot three-component reaction: synthesis of triheterocyclic 4H-pyrimido[2,1-b]benzazoles ring systems.
abstract: A novel one-pot three-component condensation reaction of an aldehyde, beta-ketoester and 2-aminobenzimidazole or 2-aminobenzothiazole in 1,1,3,3-N,N,N',N'-tetramethylguanidinium trifluoroacetate as an ionic liquid is described. During the course of this reaction 4H-pyrimido[2,1-b]benzimidazoles or 4H-pyrimido[2,1-b]benzothiazoles are formed in high yields at 100 degrees C. The ionic liquid can be recovered conveniently and reused efficiently.
authors.affiliation: Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran. a-shaabani@cc.sbu.ac.ir
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shaabani
authors.forename: Abbas
authors.initials: A
authors.lastname: Rahmati
authors.forename: Soheila
authors.initials: S
authors.lastname: Naderi
mesh_terms: D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry; D052160:Benzothiazoles; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001562:Benzimidazoles; D052160:Benzothiazoles; D006571:Heterocyclic Compounds; D011743:Pyrimidines; D013844:Thiazoles; C005465:benzothiazole