Equivalent cross-relaxation rate imaging for sentinel lymph node biopsy in breast carcinoma.
Sentinel lymph node biopsy (SLNB) is an important technique for detecting axillary lymph node metastasis in breast carcinoma patients. However, false-negative results are a problem. Equivalent cross-relaxation rate (ECR) imaging (ECRI) is a measurement method that can be used to quantitatively evaluate a change in the structural organization of lymph nodes by magnetic resonance imaging (MRI). We performed axillary ECRI in an attempt to decrease the false-negative results of SLNB. Regions without metastases showed a higher ECR value. On the other hand, regions with metastases showed a lower ECR value. The ECR images were compared with macroscopic histology images in which the presence or absence of axillary lymph node metastasis could be evaluated. ECRI is a potentially useful method for evaluating the efficacy of SLNB.
Matsushima
Shigeru
S
Department of Diagnostic Radiology, Aichi Cancer Center, Nagoya, Japan. smts@aichi-cc.jp
Sasaki
Fumio
F
Yamaura
Hidekazu
H
Iwata
Hiroji
H
Ohsaki
Hikaru
H
Era
Seiichi
S
Sogami
Masaru
M
Inaba
Tadashi
T
Uike
Mitsuhiro
M
Kinosada
Yasutomi
Y
D000328:Adult; D000368:Aged; D000465:Algorithms; D001943:Breast Neoplasms / Q000473:pathology*; D044584:Carcinoma, Ductal / Q000473:pathology* / Q000556:secondary*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*