title: Wilson disease with an initial manifestation of polyneuropathy.
abstract: BACKGROUND
  Recognition of Wilson disease (WD) is sometimes difficult because of its diverse manifestations. Peripheral neuropathy is rarely reported in the context of WD.
  
  
  OBJECTIVE
  To report an unusual patient with WD whose initial manifestation was peripheral neuropathy.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Neurology department in a tertiary referral center.
  
  
  METHODS
  Personal observation.
  
  
  RESULTS
  A 17-year-old man, who was eventually diagnosed with WD, was initially seen with polyneuropathy at least 6 months prior to developing more typical symptoms of WD. Electrophysiological and pathological studies suggested a neuropathy of mixed type. Treatment for WD resulted in clinical and electrophysiological improvement.
  
  
  CONCLUSIONS
  Wilson disease may initially appear as a treatable polyneuropathy.
authors.affiliation: Department of Neurology and Clinical Research Institute, Seoul National University Hospital, Kyung Hee University Hospital, Seoul, South Korea.
authors.forename: Keun-Hwa
authors.initials: KH
authors.lastname: Jung
authors.forename: Tae-Beom
authors.initials: TB
authors.lastname: Ahn
authors.forename: Beom S
authors.initials: BS
authors.lastname: Jeon
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology; D004594:Electrophysiology; D006527:Hepatolenticular Degeneration / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011115:Polyneuropathies / Q000209:etiology* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology