Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine.
Alopecia areata (AA) is an autoimmune disease of uncertain pathogenesis, typically treated with immunomodulators. We report the paradoxical development of AA in two kidney-pancreas transplant recipients receiving immunosuppressive therapy, which included cyclosporine. Review of the literature revealed only 7 other cases of AA occurring in solid organ transplant recipients; all occurred during long-term cyclosporine therapy. The development of AA in this population highlights the complexity of this immunologic disease.
Phillips
Mariana Abraham
MA
Department of Dermatology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Graves
Julie Elizabeth
JE
Nunley
Julia R
JR
D000328:Adult; D000506:Alopecia Areata / Q000175:diagnosis / Q000276:immunology*; D016572:Cyclosporine / Q000627:therapeutic use; D003928:Diabetic Nephropathies / Q000601:surgery; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology*; D016035:Pancreas Transplantation / Q000276:immunology*
D007166:Immunosuppressive Agents; D016572:Cyclosporine