title: Radiotherapy for maxillo-facial hemangiomas in children. Dental and periodontal long term effects.
abstract: Vascular maxillo-facial malformations, common pathologies in children, represent 7% of all benign tumors. They are divided into vascular malformations and hemangiomas. In the 70s-80s radiotherapy was the most applied technique, but because of its misuse or overdose, it could lead to relevant and hard consequences for the impact on the salivar glands, periodontium and growing maxillo-facial nuclei. The authors describe the case of a 38-year-old man, who, during infancy, was submitted to radiotherapy for a hemangioma to his chin and cheek. He was under observation for an agressive periodontitis, followed by a serious facial asimmetry, located in his irradiated side. They describe the therapy and the results obtained, underlying the particular difficulties detected in operating on tissues hardly and often irreversibly injured by radiotherapy. On the basis of this clinical case and of the most up-dated knowledge, therapeutical alternatives such as embolization, cryotherapy, cortisonic systemic and intralesional therapy, the use of interferon gamma 2 and the use of the most recent laser, are analyzed, and advantages and disadvantages and the most appropriate indications are underlined.
authors.affiliation: Department of Head and Neck Pathology, Oral Cavity and Audio-Verbal Communication, Faculty of Medicine and Surgery, Second University of Naples, Naples, Italy. guiseppe.colella@unina2.it
authors.forename: G
authors.initials: G
authors.lastname: Colella
authors.forename: G
authors.initials: G
authors.lastname: Vuolo
authors.forename: G
authors.initials: G
authors.lastname: Siniscalchi
authors.forename: A
authors.initials: A
authors.lastname: Moscariello
authors.forename: A
authors.initials: A
authors.lastname: Itro
mesh_terms: D000328:Adult; D005146:Facial Asymmetry / Q000209:etiology; D005153:Facial Neoplasms / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006391:Hemangioma / Q000532:radiotherapy*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008437:Maxilla / Q000002:abnormalities; D008441:Maxillary Neoplasms / Q000532:radiotherapy*; D010518:Periodontitis / Q000209:etiology; D011832:Radiation Injuries / Q000209:etiology; D013997:Time Factors