title: Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.
abstract: A total of 18 organosulfur compounds originating from Petiveria alliacea L. roots have been tested for their antibacterial and antifungal activities. These represent compounds occurring in fresh homogenates as well as those present in various macerates, extracts and other preparations made from Petiveria alliacea. Of the compounds assayed, the thiosulfinates, trisulfides and benzylsulfinic acid were observed to be the most active, with the benzyl-containing thiosulfinates exhibiting the broadest spectrum of antimicrobial activity. The effect of plant sample preparation conditions on the antimicrobial activity of the extract is discussed.
authors.affiliation: Department of Chemistry, State University of New York at Albany, 1400 Washington Avenue, Albany, NY 12222, USA.
authors.forename: Seokwon
authors.initials: S
authors.lastname: Kim
authors.forename: Roman
authors.initials: R
authors.lastname: Kubec
authors.forename: Rabi A
authors.initials: RA
authors.lastname: Musah
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001231:Aspergillus flavus / Q000187:drug effects; D001409:Bacillus cereus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D029602:Phytolaccaceae; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D013457:Sulfur Compounds / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts; D013457:Sulfur Compounds