title: [Comparison of PCDD/Fs content and profile in fish between marine and fresh water in a typical Chinese area].
abstract: OBJECTIVE
  To study the dioxins (polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-p-furans, PCDD/Fs) content and profile in fish from marine and fresh water in a certain water area, and to assess the dioxins intake from fish in the local people.
  
  
  METHODS
  Samples were prepared using advanced technique, confirmation and quantitative analysis of Dibenzo-p-Dioxins and Dibenzo-Furans was performed by isotope dilution HRGC/HRMS using multiple ion detection mode (MID).
  
  
  RESULTS
  The average concentration of fish from marine and fresh water was 1.43pg/g wet weight and 3.43pg/g wet weight respectively, and WHO-TEQ concentration was 0.28 and 0.43pg/g wet weight respectively. The congener-specific profile dominated by OCDD and 2,3,7,8-TCDF, and the main contributor of toxicity was 1,2,3,7,8-PeCDD, 2,3,4,7,8-PeCDF, 2,3,7,8-TCDD. The exposure from fish for local people was estimated as 0.63 pg WHO-TEQ/kg bw x day.
  
  
  CONCLUSIONS
  The level of PCDD/Fs in fresh water fish was higher than that of marine fish with one fold. The average PCDD/Fs concentration was lower than 1.0 pg WHO-TEQ/kg, which is the maximum limit (ML) set up by European Union.
authors.affiliation: Shenzhen Center for Disease Control & Prevention, Shenzhen 518020, China.
authors.forename: Jian-Qing
authors.initials: JQ
authors.lastname: Zhang
authors.forename: You-Sheng
authors.initials: YS
authors.lastname: Jiang
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Jiang
authors.forename: Zhixiong
authors.initials: Z
authors.lastname: Zhuang
authors.forename: Yongning
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000032:analysis*; D002681:China; D000072338:Dibenzofurans, Polychlorinated; D005399:Fishes; D005506:Food Contamination / Q000032:analysis*; D005618:Fresh Water; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis; D017747:Seafood / Q000032:analysis*; D012623:Seawater
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins