title: Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki disease.
abstract: We performed immunohistochemistry experiments using synthetic antibodies on the gastrointestinal tract and kidney from acute Kawasaki disease patients. Significant gastrointestinal tract inflammation was present in only 2/7 patients, who had antigen detected at the site of inflammation. Antigen was not detected in kidney from 6 patients. The presence of antigen may be related to gastrointestinal pathology in acute Kawasaki disease.
authors.affiliation: Department of Pediatrics, Northwestern University, The Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: Masaru
authors.initials: M
authors.lastname: Miura
authors.forename: Francesca L
authors.initials: FL
authors.lastname: Garcia
authors.forename: Susan E
authors.initials: SE
authors.lastname: Crawford
authors.forename: Anne H
authors.initials: AH
authors.lastname: Rowley
mesh_terms: D000208:Acute Disease; D000906:Antibodies / Q000737:chemistry / Q000276:immunology*; D000941:Antigens / Q000032:analysis*; D002648:Child; D005260:Female; D041981:Gastrointestinal Tract / Q000276:immunology* / Q000503:physiopathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007668:Kidney / Q000276:immunology; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000276:immunology* / Q000503:physiopathology
chemical_list: D000906:Antibodies; D000941:Antigens