title: [Phenotypic and functional analysis of T lymphocytes in cancer patients].
abstract: In preclinical tumor model and in human cancer, tumor antigen specific T lymphocytes play a key role in the control of tumor development. Nevertheless in numerous cases, the infiltrating tumor T cells do not seem to influence the clinical progression of the tumor. A better phenotypic and functional characterization of T cells in close contact with tumor associated with a comprehensive analysis of tumor evasion mechanism to the host response should lead to an optimization of cancer immunotherapy protocols.
authors.affiliation: INSERM U 255, Institut Biomédical des Cordeliers, Université Paris 5.
authors.forename: Cécile
authors.initials: C
authors.lastname: Badoual
authors.forename: Benoît
authors.initials: B
authors.lastname: Vingert
authors.forename: Nour
authors.initials: N
authors.lastname: Agueznay
authors.forename: Olivier
authors.initials: O
authors.lastname: Adotevi
authors.forename: Nacilla
authors.initials: N
authors.lastname: Haicheur
authors.forename: Thierry
authors.initials: T
authors.lastname: Molina
authors.forename: Patrick
authors.initials: P
authors.lastname: Bruneval
authors.forename: Wolf H
authors.initials: WH
authors.lastname: Fridman
authors.forename: Eric
authors.initials: E
authors.lastname: Tartour
mesh_terms: D015703:Antigens, CD / Q000276:immunology; D006801:Humans; D016246:Lymphocytes, Tumor-Infiltrating / Q000473:pathology; D009369:Neoplasms / Q000276:immunology* / Q000473:pathology*; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology*
chemical_list: D015703:Antigens, CD