Conjunctival necrosis following intravitreal injection of triamcinolone acetonide.
OBJECTIVE
To report a case of localized conjunctival necrosis following intravitreal injection of triamcinolone acetonide (TA).


METHODS
Single observational case report.


METHODS
A 63-year- old man presented with inferotemporal branch retinal vein occlusion and macular edema in his left eye (OS). He underwent pars plana vitrectomy combined with arteriovenous sheathotomy. Postoperatively, as the macular edema persisted, he underwent an uneventful intravitreal injection of TA.


RESULTS
Ten days following the intravitreal injection, he presented with an area of localized conjunctival necrosis overlying the scleral entry site. Gram stain showed a few white blood cells and no organisms. The conjunctival swab showed no growth on culture. The area of conjunctival necrosis responded well to intense topical antibiotic therapy.


CONCLUSIONS
Conjunctival necrosis is a rare anterior segment complication of intravitreal injection of TA. With the increased usage of intravitreal TA for various posterior segment disorders, the treating physician should be aware of this complication.
Srinivasan
Sathish
S
Department of Ophthalmology, Arrowe Park Hospital, Wirral, UK. sathish@tiscali.co.uk
Prasad
Somdutt
S
D003228:Conjunctiva / Q000187:drug effects / Q000473:pathology*; D003229:Conjunctival Diseases / Q000139:chemically induced* / Q000473:pathology; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D014221:Triamcinolone / Q000008:administration & dosage / Q000009:adverse effects*; D014821:Vitrectomy; D014822:Vitreous Body
D005938:Glucocorticoids; D014221:Triamcinolone