Active telephone surveillance to evaluate adverse events among civilian smallpox vaccine recipients.
OBJECTIVE
Better characterize and monitor adverse events following Dryvax vaccinia vaccination in civilian health care workers and other first responders.


METHODS
Telephone interviews to ascertain adverse events experienced.


RESULTS
Eight hundred twenty-five vaccinees, including 44 in the comparison group, were interviewed. At 10 days, 71.4% reported blisters, 35.1% reported bumps at the vaccination site, 48.5% swelling, 47.3% scab, tiredness/lethargy/fatigue (43.6%), headache (34.2%), lymph node swelling/tenderness (28.5%), muscle pain (23.1%), chills (14.4%), joint pain 11.8%, and fever >100 degrees F (12.5%). The 12.5% reported missing work because of vaccine adverse events. Most adverse events were anticipated and of short duration.
Muralles
Arnulfo A
AA
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Ray
Paula
P
Black
Steven
S
Shinefield
Henry
H
Casey
Christine G
CG
Campbell
Scott
S
Chen
Robert T
RT
D016907:Adverse Drug Reaction Reporting Systems; D000075202:Contraindications; D006801:Humans; D007407:Interviews as Topic; D011159:Population Surveillance; D015980:Public Health Practice / Q000592:standards*; D012900:Smallpox Vaccine / Q000009:adverse effects*; D014611:Vaccination / Q000009:adverse effects*
D012900:Smallpox Vaccine