Lights, camera, actin.
Actin participates in many important biological processes. Currently, intensive investigation is being carried out in a number of laboratories concerning the function of actin in these processes and the molecular basis of its functions. We present a glimpse into four of these areas: actin-like proteins in bacterial cells, actin in the eukaryotic nucleus, the conformational plasticity of the actin filament, and finally, Arp2/3-dependent regulation of actin filament branching and creation of new filament barbed ends.
Rubenstein
Peter A
PA
Department of Biochemistry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA. peter-rubenstein@uiowa.edu
Wen
Kuo-Kuang
KK
D051376:Actin-Related Protein 2-3 Complex / Q000737:chemistry; D000199:Actins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D002467:Cell Nucleus / Q000502:physiology; D029968:Escherichia coli Proteins / Q000378:metabolism; D006801:Humans; D008958:Models, Molecular; D011487:Protein Conformation; D029701:Saccharomyces cerevisiae Proteins / Q000502:physiology; D051316:Wiskott-Aldrich Syndrome Protein / Q000502:physiology
D051376:Actin-Related Protein 2-3 Complex; D000199:Actins; D029968:Escherichia coli Proteins; C480361:LAS17 protein, S cerevisiae; C471255:ParM protein, E coli; D029701:Saccharomyces cerevisiae Proteins; D051316:Wiskott-Aldrich Syndrome Protein; C078473:MreB protein, E coli