title: Clinical and socio-economic impact of influenza and respiratory syncytial virus infection on healthy children and their households.
abstract: This prospective study compared the clinical and socio-economic impact of laboratory-confirmed influenza and respiratory syncytial virus (RSV) infection on healthy children and their families. Among 1,520 otherwise healthy children aged< 15 years attending the Emergency Department for acute conditions other than trauma, influenza viruses and RSV were found in 234 (15.4%) and 116 (7.6%; p<0.0001) patients, respectively. The fact that influenza has a similar global clinical impact on the community to that of RSV infection, but represents a greater socio-economic burden, may contribute to broadening the acceptance of influenza vaccination.
authors.affiliation: Institute of Pediatrics, Fondazione IRCCS 'Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena', University of Milan, Milan, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Esposito
authors.forename: R
authors.initials: R
authors.lastname: Gasparini
authors.forename: S
authors.initials: S
authors.lastname: Bosis
authors.forename: P
authors.initials: P
authors.lastname: Marchisio
authors.forename: C
authors.initials: C
authors.lastname: Tagliabue
authors.forename: S
authors.initials: S
authors.lastname: Tosi
authors.forename: C
authors.initials: C
authors.lastname: Bianchi
authors.forename: P
authors.initials: P
authors.lastname: Crovari
authors.forename: N
authors.initials: N
authors.lastname: Principi
mesh_terms: D002648:Child; D002675:Child, Preschool; D005191:Family Characteristics; D005192:Family Health; D006801:Humans; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000191:economics* / Q000503:physiopathology*; D009975:Orthomyxoviridae; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000191:economics* / Q000503:physiopathology*; D018113:Respiratory Syncytial Virus, Human
chemical_list: D007252:Influenza Vaccines