title: Hippocampal involvement in dengue fever.
abstract: Flaviviruses are among the most important emerging viruses known to man. Dengue is the most common flavivirus infection in Singapore, and is transmitted between humans by the Aedes mosquito. We report a 25-year-old man with dengue fever complicated by selective hippocampal involvement manifesting as amnesia. This has not been described in the literature previously. Dengue polymerase chain reaction and serology were positive. Magnetic resonance imaging of the brain showed bilateral hippocampal involvement.
authors.affiliation: Department of General Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. daniel_yeo@ttsh.com.sg
authors.forename: P S D
authors.initials: PS
authors.lastname: Yeo
authors.forename: L
authors.initials: L
authors.lastname: Pinheiro
authors.forename: P
authors.initials: P
authors.lastname: Tong
authors.forename: P L
authors.initials: PL
authors.lastname: Lim
authors.forename: Y Y
authors.initials: YY
authors.lastname: Sitoh
mesh_terms: D000328:Adult; D000647:Amnesia / Q000209:etiology*; D001927:Brain Diseases / Q000209:etiology*; D003715:Dengue / Q000150:complications*; D018177:Flavivirus Infections / Q000150:complications; D006624:Hippocampus / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male