title: Annular elastolytic giant cell granuloma in an infant: improvement after treatment with oral tranilast and topical pimecrolimus.
abstract: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-old boy that was successfully treated with oral tranilast and topical pimecrolimus (Elidel 1.0% cream).
authors.affiliation: Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
authors.forename: Hae-Woong
authors.initials: HW
authors.lastname: Lee
authors.forename: Mi-Woo
authors.initials: MW
authors.lastname: Lee
authors.forename: Jee-Ho
authors.initials: JH
authors.lastname: Choi
authors.forename: Kee-Chan
authors.initials: KC
authors.lastname: Moon
authors.forename: Jai-Kyoung
authors.initials: JK
authors.lastname: Koh
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004547:Elastic Tissue / Q000473:pathology*; D016460:Granuloma Annulare / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D062367:ortho-Aminobenzoates / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D018926:Anti-Allergic Agents; D007166:Immunosuppressive Agents; D062367:ortho-Aminobenzoates; C117268:pimecrolimus; C012293:tranilast; D016559:Tacrolimus