title: [Left ventricular mass and systolic-diastolic function of the heart in children and adolescents with hypertension and hypertension accompanying obesity].
abstract: Arterial hypertension in paediatric population occurs in 1-2%. This disorder is a subject of increasing interest in the young age group already, because after many years it leads to progress of complications in circulatory system. Hypertension is an independent risk factor for cardiovascular incidents. In patients with hypertension and left ventricular hypertrophy mortality is 2-4 times greater than in the general population. The aim of the study was to answer the question if there are any disturbances in systolic-diastolic function and changes in left ventricle mass of the heart in hypertensive children and adolescents.
  
  
  METHODS
  The study group consisted of 74 children and adolescents aged 11-19. The group was divided into: group A-33 children with hypertension and group B--23 patients with hypertension and coexisting obesity. Control group was 18 healthy children. Left ventricle heart mass and systolic-diastolic function were assessed by ultrasonography with Agilent Technology Sonos 4500.
  
  
  RESULTS
  In children with arterial hypertension and coexisting obesity we found significantly higher contractility (p < 0.01), ejectile fraction of left ventricle (p < 0.05), higher ratio E/A (p < 0.01), higher E wave of diastolic inflow, shorten deceleration time of E wave (p < 0.01) and higher lef ventricle heart mass (p < 0.05) compared to controls and hypertensive children.
  
  
  CONCLUSIONS
  In children with hypertension and obesity we found the highest contractility of the heart muscle and E/A values and higher left ventricle mass. Young patients with hypertension, especially with hypertension coexisting with obesity should have their circulatory system monitored (by echocardiography) in order to apply appropriate therapeutic strategies.
authors.affiliation: II Klinika Chorób Dzieci Akademii Medycznej w Białymstoku.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Baszun-Stepaniuk
authors.forename: Mirosława
authors.initials: M
authors.lastname: Urban
authors.forename: Barbara
authors.initials: B
authors.lastname: Głowińska
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D003971:Diastole; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D009765:Obesity / Q000150:complications*; D011044:Poland; D012307:Risk Factors; D018709:Statistics, Nonparametric; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology*