title: Some changes of the heart bioelectric activity at the cosmonauts under the influence of LBNP in the long duration flights.
abstract: There was selected the group of the cosmonauts, who carry out long duration flights on the orbital complex "Mir", in which the tolerance of LBNP test was evaluated as poor (by hemodynamic indices--heart rate, arterial pressure, rheoencephalographic indices). The in-depth analysis of the electrocardiogram (in DS leads) indices was carry oiled on possible disturbances of conductivity and dynamics of temporary or amplitude characteristics. Furthermore is carry oiled the comparative estimation of these indices with the results of ECG analysis at the cosmonauts, who tolerance test good. Studies showed that the most informative ECG indices are the R, T-amplitudes and QT-interval. Under the influence of LBNP, especially during rarefactions on 45 and 50 mm Hg was noted reduction in the R, T-amplitude and the relative extension of QT-interval. The directivity of changes in these indices are identical for the cosmonauts with good and poor tolerance of the test; however in flight manifestation of the changes is more significant for the cosmonauts with poor tolerance of LBNP test. Thus, in the formation of orthostatic stability together with the hemodynamic influences take part the bioelectric processes, which are formed in the myocardium.
authors.affiliation: State Scientific Center of Russian Federation Institute for Biomedical Problems of the Russian Academy of Science, Moscow, Russia. gmo2@mcc.rsa.ru
authors.forename: S O
authors.initials: SO
authors.lastname: Shelepnevich
authors.forename: I V
authors.initials: IV
authors.lastname: Alferova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Golybchicova
mesh_terms: D000337:Aerospace Medicine; D018480:Astronauts; D001794:Blood Pressure / Q000502:physiology; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008150:Lower Body Negative Pressure; D009206:Myocardium / Q000378:metabolism*; D013026:Space Flight; D014893:Weightlessness / Q000009:adverse effects*