title: FtsZ and the division of prokaryotic cells and organelles.
abstract: Binary fission of many prokaryotes as well as some eukaryotic organelles depends on the FtsZ protein, which self-assembles into a membrane-associated ring structure early in the division process. FtsZ is homologous to tubulin, the building block of the microtubule cytoskeleton in eukaryotes. Recent advances in genomics and cell-imaging techniques have paved the way for the remarkable progress in our understanding of fission in bacteria and organelles.
authors.affiliation: Department of Microbiology and Molecular Genetics, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030, USA. William.Margolin@uth.tmc.edu
authors.forename: William
authors.initials: W
authors.lastname: Margolin
mesh_terms: D001419:Bacteria / Q000166:cytology* / Q000648:ultrastructure; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology*; D002455:Cell Division; D003598:Cytoskeletal Proteins / Q000737:chemistry / Q000502:physiology*; D015388:Organelles / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; C071525:FtsZ protein, Bacteria