Syntheses of S-enantiomers of hanishin, longamide B, and longamide B methyl ester from L-aspartic acid beta-methyl ester: establishment of absolute stereochemistry.
[reaction: see text] Total syntheses of enantiopure hanishin, longamide B, and longamide B methyl ester are described. Absolute configurations of these natural products have been established.
Patel
Jignesh
J
LEDSS, UMR 5616 CNRS, Institut de Chimie Moléculaire de Grenoble - FR 2607, Université Joseph Fourier, France.
Pelloux-Léon
Nadia
N
Minassian
Frédéric
F
Vallée
Yannick
Y
D001224:Aspartic Acid / Q000737:chemistry*; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D004952:Esters; D011758:Pyrroles; C511000:hanishin; C511002:longamide B; C511001:longamide B methyl ester; D001224:Aspartic Acid