Gravitation in pathogeny of essential hypertension.
The purpose of this research is the study of changes of a systemic hemodynamics under passive orthostatic test for a healthy persons and an ill with Essential Hypertension (EH) and analysis of a possible role of the gravitational factor in a Pathogeny of this disease. For an ill with EH reduction of Stroke Volume and Cardiac Output were reliably lower in an orthostatic position. Increasing of a Total peripheral vascular resistance was twice less for ill. Considerable differences in reaction of cardiovascular system to gravitational influence for an ill with Essential Hypertension are stipulated by changes in central regulation of circulation and in the structure of a vascular wall. It allows to assume influence of gravitation at early stages of a Pathogeny of the given disease. The detection of hyper reactivity of a cardiovascular system to influence of gravitation can indicate the first stage of the disease.
Dorogovtsev
V N
VN
Principal Military Hospital of Angola, Luanda, Angola.
D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D005260:Female; D006112:Gravitation; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D007024:Hypotension, Orthostatic / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000502:physiology