title: Toxicity of ionic liquids and organic solvents to lactic acid-producing bacteria.
abstract: In situ extractive fermentation of lactic acid using organic solvents has already been extensively investigated. Now ionic liquids are emerging as alternative solvents for volatile organic compounds traditionally used in liquid-liquid extraction. In this study, we examine whether lactic acid producing-bacteria can grow in the presence of a second phase of imidazolium-based ionic liquids or organic solvents. The lactic acid producing-bacteria used in this study are sensitive to organic solvents having 1 < log P < 4. We found that Lactobacillus delbruekii subsp. lactis NRIC 1683 could grow in the presence of a second phase of imidazolium-based ionic liquids as well as in the absence of the ionic liquids.
authors.affiliation: Department of Chemical Engineering and Materials Science, Doshisha University, 1-3 Miyakodani, Tatara, Kyotanabe, Kyoto 610-0321, Japan. mmatsumo@mail.doshisha.ac.jp
authors.forename: Michiaki
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Mochiduki
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kondo