title: Pitfalls in predicting resting energy requirements in critically ill children: a comparison of predictive methods to indirect calorimetry.
abstract: BACKGROUND
  Critical illness in children is thought to have profound effects on nutritional status. It is essential to avoid complications associated with inadequate nutrition support and delivery of excess energy.
  
  
  OBJECTIVE
  To compare the results of several commonly used methods for predicting energy requirements in a group of critically ill children indirect calorimetry was used to measure energy expenditure in these children.
  
  
  METHODS
  Resting energy expenditures estimated by different prediction methods for energy were compared with measurements of actual resting energy expenditure obtained by indirect calorimetry in 52 children admitted to a pediatric intensive care unit. Agreement between each predictive method and indirect calorimetry was evaluated by Bland-Altman limits of agreement and by whether the methods met the predetermined criterion for accuracy of within 10% of the measured value.
  
  
  RESULTS
  None of the equations predicted individual values accurately. Each of the predictive equations gave a wide and variable scatter of predicted values around the median. The recommended dietary allowance for energy was the least accurate and differed significantly even from the other predictive methods, overestimating energy expenditure in 50 of 52 patients. None of the remaining methods stood out as being more precise.
  
  
  CONCLUSIONS
  Predictive methods commonly used to estimate energy expenditure in critically ill children are very imprecise and may lead to overprovision or underprovision of nutrition support. Resting energy expenditure should be measured by indirect calorimetry whenever possible.
authors.affiliation: Pediatric Gastroenterology and Nutrition, MP-126, Rhode Island Hospital, 593 Eddy St., Providence, Rhode Island 02903, USA. chardy@lifespan.org
authors.forename: Christine M
authors.initials: CM
authors.lastname: Hardy
authors.forename: Johanna
authors.initials: J
authors.lastname: Dwyer
authors.forename: Linda K
authors.initials: LK
authors.lastname: Snelling
authors.forename: Gerard E
authors.initials: GE
authors.lastname: Dallal
authors.forename: Joel W
authors.initials: JW
authors.lastname: Adelson