Intracellular survival mechanisms of Francisella tularensis, a stealth pathogen.
Research on the highly virulent and contagious, facultative intracellular bacterium Francisella tularensis has come into the limelight recently, but still little is known regarding its virulence mechanisms. This review summarizes recent studies on its intramacrophage survival mechanisms, some of which appear to be novel.
Sjöstedt
Anders
A
Department of Clinical Microbiology, Clinical Bacteriology, Umeå University, 90185 Umeå, Sweden. Anders.Sjostedt@climi.umu.se
D000818:Animals; D042783:Endothelial Cells / Q000382:microbiology*; D005604:Francisella tularensis / Q000235:genetics / Q000254:growth & development* / Q000472:pathogenicity*; D006801:Humans; D008264:Macrophages / Q000382:microbiology*; D051379:Mice; D014406:Tularemia / Q000382:microbiology; D014774:Virulence