Tablets with high lactose content: effects of some binders and disintegrants on their properties.
Tablets containing 91% lactose monohydrate and 4% starch pregelatinized exhibited the best technical properties in comparison to tablets of similar composition with either povidone plus croscarmellose sodium or hydroxypropylcellulose low substituted as binders/disintegrants.
Eyjolfsson
R
R
Drug Development, Hafnarfjordur, Iceland.
D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D005079:Excipients; D007785:Lactose / Q000737:chemistry*; D010592:Pharmaceutic Aids / Q000737:chemistry; D011205:Povidone / Q000737:chemistry; D013213:Starch; D013607:Tablets
D005079:Excipients; D010592:Pharmaceutic Aids; D013607:Tablets; D002482:Cellulose; D013213:Starch; C008079:hydroxypropylcellulose; D011205:Povidone; D007785:Lactose