title: Group C streptococcal sepsis complicating Fournier gangrene.
abstract: Fournier gangrene is a life-threatening necrotizing fasciitis of the perineal-scrotal area that occurs in diabetic males. Patients typically present with systemic toxicity and significant inflammatory changes in the scrotum and perineum. Most cases of Fournier gangrene are polymicrobic and require urgent surgical debridement and broad-spectrum antibiotic therapy. We describe a case of Fournier gangrene in a young diabetic man that was associated with group C streptococcal bacteremia, an association previously unreported in the literature to our knowledge.
authors.affiliation: Wright State University School of Medicine, Dayton, OH, USA. Mmarinella@pol.net
authors.forename: Mark A
authors.initials: MA
authors.lastname: Marinella
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D003646:Debridement; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004338:Drug Combinations; D018934:Fournier Gangrene / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008297:Male; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010502:Perineum / Q000382:microbiology / Q000473:pathology; D010878:Piperacillin / Q000627:therapeutic use; D012611:Scrotum / Q000382:microbiology / Q000473:pathology; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology*; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy; D000078142:Tazobactam
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D010397:Penicillanic Acid; D000078142:Tazobactam; D010878:Piperacillin