title: Comparison of laparoscopic versus open repair for perforated duodenal ulcers.
abstract: BACKGROUND
  There is great controversy regarding the choice of procedure for perforated duodenal ulcer patients. The purpose of this study was to compare the early outcome results of laparoscopic and open repair and to propose which risk factors influence the outcome.
  
  
  METHODS
  Between October 1996 and May 2004, 60 patients underwent laparoscopic and 162 patients underwent open repair of perforated peptic ulcers in a tertiary care academic center. The results were retrospectively analyzed. The primary outcome measures included operative time, duration of hospital stay, morbidity, and mortality.
  
  
  RESULTS
  The operative time was significantly longer in the laparoscopy group compared to the open repair group (76.2 +/- 35.3 vs 57.3 +/- 26.1 min, respectively). The hospital stay in surviving patients appeared to be significantly shorter after laparoscopy than after open repair (7.8 +/- 5.3 vs 10.3 +/- 10.6 days, respectively). Eight patients (13%) in the laparoscopic group and 41 patients (25%) in the open repair group had morbidity in the postoperative period. Suture leakage was confirmed in four patients (7%) following laparoscopic repair and in three patients (2%) in the open repair group. There were 20 deaths (9%), all in the open repair group.
  
  
  CONCLUSIONS
  Independent Boey risk factors, patient age, and large perforation size have a negative impact on patient recovery. Both laparoscopic and open repair are equally safe and effective in perforated duodenal ulcer patients with a Boey score of 0 or 1.
authors.affiliation: Clinic of General and Plastic Surgery, Orthopedics and Trauma Surgery, Vilnius University, 29 Siltnamiu Street, Vilnius, LT-04130, Lithuania. rlunevichus@yahoo.com
authors.forename: R
authors.initials: R
authors.lastname: Lunevicius
authors.forename: M
authors.initials: M
authors.lastname: Morkevicius
mesh_terms: D000328:Adult; D013505:Digestive System Surgical Procedures / Q000009:adverse effects / Q000379:methods; D004381:Duodenal Ulcer / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects; D008297:Male; D010439:Peptic Ulcer Perforation / Q000209:etiology* / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors