title: [Risk factors for osteoarthritis of the knee: current status].
abstract: The development of arthrosis is best understood paradigmatically as the result of an interaction between individual and systemic risk factors. This review of the current literature on the subject identifies overweight, occupational exposure to repeated daily lifting and the postmenopausal decline in gonadal steroids in women as significant risk factors for the development of symptomatic and radiologic osteoarthritis of the knee.
authors.affiliation: H:S Hvidovre Hospital, Ortopaedkirurgisk Afdeling. clauslindkaer@jensen.mail.dk
authors.forename: Claus Lindkaer
authors.initials: CL
authors.lastname: Jensen
authors.forename: Steffen
authors.initials: S
authors.lastname: Jacobsen
authors.forename: Stig
authors.initials: S
authors.lastname: Sonne-Holm
mesh_terms: D000367:Age Factors; D001265:Athletic Injuries / Q000150:complications; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D017770:Lifting / Q000009:adverse effects; D008297:Male; D009765:Obesity / Q000150:complications; D016273:Occupational Exposure / Q000009:adverse effects; D020370:Osteoarthritis, Knee / Q000209:etiology* / Q000235:genetics; D012307:Risk Factors; D012737:Sex Factors