title: Magnetic resonance spectra of hyperpolarized (129)xe in human blood and living rat chest.
abstract: We constructed a gas polarization system to test the feasibility of using hyperpolarized (129)Xe gas as an NMR (nuclear magnetic resonance) probe to explore brain function. Both in vitro and in vivo experiments were performed with a 4.7 T NMR spectrometer. Xenon spectra from human blood confirmed the existence of two peaks corresponding to red blood cells and plasma. In rat studies, three peaks at around 200 ppm were observed. Our results are consistent with previously reported data.
authors.affiliation: Akita Research Institute of Brain and Blood Vessels, 6-10 Senshu-kubota machi, Akita 010-0874, Japan. wakai@akita-noken.go.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Wakai
authors.forename: Jeff
authors.initials: J
authors.lastname: Kershaw
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Nakamura
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Iida
authors.forename: Hajime
authors.initials: H
authors.lastname: Tamura
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kondoh
authors.forename: Iwao
authors.initials: I
authors.lastname: Kanno
mesh_terms: D000818:Animals; D005240:Feasibility Studies; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013909:Thorax; D014979:Xenon Isotopes / Q000097:blood*
chemical_list: D014979:Xenon Isotopes