Theoretical approach to blood ejection from the human left ventricle.
An ejection dynamics mathematical model of human left ventricle (LV) based on physiological data of human heart is proposed in this study. The mathematical equations were expressed in terms of vorticity-stream function equations in a prolate spheroidal coordinate system. These equations combined with specified boundary conditions were numerically solved by using an alternating-direction-implicit (ADI) algorithm with second order accuracy. The unsteady aspects of the ejection process were subsequently introduced into the numerical simulation. The numerical results have shown that the present ellipsoidal model could be available to simulate the ejection process of the human LV. Such a model combined with cardiac muscle mechanics could be studied further to determine altered left ventricular function in cardiac diseases.
Peng
Yuhua
Y
Beijing Institute of Technology, Department of Biomedical Engineering, 100081 Beijing, China.
Wu
Shigui
S
Geng
Shizhao
S
Liepsch
Dieter
D
Liao
Donghua
D
Qiao
Aike
A
Zeng
Yanjun
Y
D000328:Adult; D001011:Aorta / Q000502:physiology; D001696:Biomechanical Phenomena; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000502:physiology*; D006352:Heart Ventricles; D006801:Humans; D008955:Models, Cardiovascular; D012039:Regional Blood Flow; D013318:Stroke Volume / Q000502:physiology*