Magnetic resonance spectra of hyperpolarized (129)xe in human blood and living rat chest.
We constructed a gas polarization system to test the feasibility of using hyperpolarized (129)Xe gas as an NMR (nuclear magnetic resonance) probe to explore brain function. Both in vitro and in vivo experiments were performed with a 4.7 T NMR spectrometer. Xenon spectra from human blood confirmed the existence of two peaks corresponding to red blood cells and plasma. In rat studies, three peaks at around 200 ppm were observed. Our results are consistent with previously reported data.
Wakai
Atsushi
A
Akita Research Institute of Brain and Blood Vessels, 6-10 Senshu-kubota machi, Akita 010-0874, Japan. wakai@akita-noken.go.jp
Kershaw
Jeff
J
Nakamura
Kazuhiro
K
Iida
Hidehiro
H
Tamura
Hajime
H
Kondoh
Yasushi
Y
Kanno
Iwao
I
D000818:Animals; D005240:Feasibility Studies; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013909:Thorax; D014979:Xenon Isotopes / Q000097:blood*
D014979:Xenon Isotopes