title: [A particular hepatocellular carcinoma combining the ordinary and the fibrolamellar variant].
abstract: Fibrolamellar carcinoma (FLC) of the liver is a rare variant of hepatocellular carcinoma (HCC) occurring on non cirrhotic liver. Since its first description by Hugh Edmondson in 1956, 200 cases of FLC have been reported in the literature, but only some cases describe the association of the ordinary HCC with the FLC within the same lesion. We report in this study the case of a 14-year-old female patient with a hepatic mass whose radiological aspect evoked a nodular and focal hyperplasia. Histologically, this tumor was composed of area of FLC mixed with ordinary HCC. Staining for cytokeratine 7 was positive in the FL component and negative in the ordinary HCC component.
authors.affiliation: Service d'anatomie et de cytologie pathologique, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Rachida
authors.initials: R
authors.lastname: Zermani
authors.forename: Lamia
authors.initials: L
authors.lastname: Charfi
authors.forename: Nadia
authors.initials: N
authors.lastname: Kourda
authors.forename: Faten
authors.initials: F
authors.lastname: Farah
authors.forename: Soumaya
authors.initials: S
authors.lastname: Rammeh
authors.forename: Omar
authors.initials: O
authors.lastname: Trabelsi
authors.forename: Abdejlil
authors.initials: A
authors.lastname: Zaouch
authors.forename: Sarra
authors.initials: S
authors.lastname: Ben Jilani
mesh_terms: D000293:Adolescent; D006528:Carcinoma, Hepatocellular / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D053552:Keratin-7; D007633:Keratins / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins