Gastric adenocarcinoma with ossification in a ferret (Mustela putorius furo).
A 6-year-old female ferret had a firm mass 2 cm in diameter in the pyloric region of the stomach. Histopathologically, the mass was composed of neoplastic proliferation of well-differentiated epithelial cells, showing tubular or glandular growth patterns. Osseous metaplastic foci were often found in the tumor. Tumor cells showed a positive reaction for immunohistochemistry against bone morphogenetic protein-6, an osteogenic factor. A diagnosis of gastric adenocarcinoma with ossification was made.
Nakanishi
Masako
M
Laboratory of Veterinary Pathology, Osaka Prefecture University, and Kitasuma Animal Hospital, Kobe, Japan.
Kuwamura
Mitsuru
M
Yamate
Jyoji
J
Fujita
Daisuke
D
Sasai
Hiroshi
H
D000230:Adenocarcinoma / Q000473:pathology* / Q000662:veterinary*; D000818:Animals; D055418:Bone Morphogenetic Protein 6; D019485:Bone Morphogenetic Proteins / Q000378:metabolism; D005289:Ferrets; D007150:Immunohistochemistry / Q000662:veterinary; D013274:Stomach Neoplasms / Q000473:pathology* / Q000662:veterinary*
D055418:Bone Morphogenetic Protein 6; D019485:Bone Morphogenetic Proteins