title: [Investigation of the drug "Mamoclam" for the treatment of patients with fibroadenomatosis of the breast].
abstract: The clinical trial of a new drug "mamoclam" was carried out in patients with benign breast disease. The drug contains omega-3 polyunsaturated fatty acids, iodine and chlorophyll derivatives and is produced from the brown sea alga laminaria. The study involved 33 patients (mean age 42.5 +/- 1.1 yrs). Two tablets were administered thrice a day for three months. Examination included clinical evaluation of symptoms of mastopathy and dysalgomenorrhea, breast sonography and mammography. Therapeutic response presented as reduced mastalgia, premenopausal syndrome, dysmenorrhea and algomenorrhea, breast cyst regression as well as attenuated pain associated with benign breast disease and palpation. Positive response was reported in 94%. The drug should be recommended for benign breast disease treatment.
authors.forename: V G
authors.initials: VG
authors.lastname: Bezpalov
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Barash
authors.forename: O A
authors.initials: OA
authors.lastname: Ivanova
authors.forename: I I
authors.initials: II
authors.lastname: Semënov
authors.forename: V A
authors.initials: VA
authors.lastname: Aleksandrov
authors.forename: V F
authors.initials: VF
authors.lastname: Semiglazov
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D002734:Chlorophyll / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D018226:Fibroadenoma / Q000188:drug therapy*; D006801:Humans; D007455:Iodine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D015525:Fatty Acids, Omega-3; C504874:mamoclam; D002734:Chlorophyll; D007455:Iodine