title: Therapeutic approaches to Chlamydia infections.
abstract: Chlamydia trachomatis ocular and urogenital infections represent major public health problems, whereas Chlamydophila pneumoniae is a common aetiological agent of community-acquired pneumonia. The obligate intracellular lifestyle of these established pathogens poses challenges to both their diagnosis and treatment. Tetracyclines, macrolides and quinolones remain the antimicrobials of choice for the treatment of infections due to Chlamydiaceae.
authors.affiliation: Department of Internal Medicine, University Hospital, Lausanne, Switzerland.
authors.forename: Laurence
authors.initials: L
authors.lastname: Senn
authors.forename: Margaret R
authors.initials: MR
authors.lastname: Hammerschlag
authors.forename: Gilbert
authors.initials: G
authors.lastname: Greub
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000187:drug effects* / Q000302:isolation & purification; D016993:Chlamydophila pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D003235:Conjunctivitis, Inclusion / Q000188:drug therapy* / Q000382:microbiology; D052776:Female Urogenital Diseases / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology / Q000627:therapeutic use; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D017410:Practice Guidelines as Topic; D015363:Quinolones / Q000494:pharmacology / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D013754:Tetracyclines / Q000494:pharmacology / Q000627:therapeutic use; D014141:Trachoma / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D015363:Quinolones; D013754:Tetracyclines