title: Use of long-term combined therapy with inhaled iloprost and oral sildenafil in an adult patient with eisenmenger syndrome.
abstract: Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatment alternatives when the patient is not a candidate for surgery. In this article, we report on the case of a 68-year-old woman with Eisenmenger syndrome related to congenital heart disease who was treated with inhaled iloprost and oral sildenafil for 2 years.
authors.affiliation: Department of Cardiology, Gazi University Medical School, Ankara, Turkey. drokyay@yahoo.com
authors.forename: Kaan
authors.initials: K
authors.lastname: Okyay
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cemri
authors.forename: Bulent
authors.initials: B
authors.lastname: Boyac
authors.forename: Rdvan
authors.initials: R
authors.lastname: Yalcn
authors.forename: Atiye
authors.initials: A
authors.lastname: Cengel
mesh_terms: D000280:Administration, Inhalation; D000284:Administration, Oral; D000368:Aged; D017023:Coronary Angiography; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004541:Eisenmenger Complex / Q000175:diagnosis / Q000188:drug therapy*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D016285:Iloprost / Q000008:administration & dosage*; D010879:Piperazines / Q000008:administration & dosage*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; D016285:Iloprost