title: [Plasma cell leukaemia].
abstract: We report a case of primary plasma cell leukaemia, with an absolute count of plasma cells of 53 Giga/L, diagnosed in a 83-year-old woman. The patient's condition improved, with no circulating plasma cells after 3 weeks of treatment, in response to the combination of thalidomide and dexamethasone administered for 5 days followed by thalidomide alone. The clinical presentation, the morphological, flow cytometric and pathophysiological characteristics of the plasma cell leukaemia and the treatment are summarised in this paper.
authors.affiliation: Laboratoire d'hématologie, Groupe hospitalier Charles Foix Jean Rostand, Ivry Sur Seine.
authors.forename: C
authors.initials: C
authors.lastname: Rodriguez
authors.forename: J-C
authors.initials: JC
authors.lastname: Pont
authors.forename: I
authors.initials: I
authors.lastname: Gouin-Thibault
authors.forename: A-G
authors.initials: AG
authors.lastname: Andrieu
authors.forename: T
authors.initials: T
authors.lastname: Molina
authors.forename: A
authors.initials: A
authors.lastname: Le Tourneau
authors.forename: M
authors.initials: M
authors.lastname: Le Garff-Tavernier
authors.forename: V
authors.initials: V
authors.lastname: Siguret
authors.forename: P
authors.initials: P
authors.lastname: Chaibi
mesh_terms: D000369:Aged, 80 and over; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000175:diagnosis* / Q000188:drug therapy; D013792:Thalidomide / Q000627:therapeutic use*
chemical_list: D020533:Angiogenesis Inhibitors; D000893:Anti-Inflammatory Agents; D013792:Thalidomide; D003907:Dexamethasone