title: [Efficacy and safety of laser-assisted in situ keratomileusis for myopia].
abstract: BACKGROUND
  The aim of this study was to assess the efficacy, frequency of re-operation and type and frequency of complications after laser-assisted in situ keratomileusis (LASIK) treatment for moderate to high levels of myopia.
  
  
  METHODS
  357 eyes from 190 patients were reviewed. The mean of the preoperative correction was -8.38 D (-1.75; -16 D) sph. (spherical), -1.00 D (0; 4.5 D) astigmatism. 15% (55 eyes) were re-treated. The mean of the correction before re-treatment was -2.78 D (+2.25; -11.00 D) sph., -0.43 D (0; -2.00 D) astigmatism.
  
  
  RESULTS
  The three-month follow-up rate was 96% for primarily treated eyes and 99% for re-treated eyes. Where full correction was intended, 53% of the primarily treated and 93% of the re-treated eyes achieved an uncorrected visual acuity of > or =0.5. The refractive error for myopia less than -8 D was -0.80 D +/- 0.83 D and -1.37 D +/- 1.33 D for myopia -8 D and above after one treatment and -0.47 +/- 0.66 D after re-treatment. 1.2% (4) of the primarily treated and 3.9% (2) of the retreated eyes lost more than two lines in best spectacle-corrected visual acuity (BCVA).
  
  
  CONCLUSIONS
  LASIK treatment for moderate to high levels of myopia leads in all cases to a reduced degree of myopia. There is a significant degree of unreliability on the accuracy of the treatment with a tendency to under correction. Postoperatively, many patients still have to use correction for distance vision. Significant loss of visual acuity occurs infrequently.
authors.affiliation: Arhus Universitetshospital, Arhus Sygehus, Øjenafdelingen.
authors.forename: Mette Hjuler
authors.initials: MH
authors.lastname: Beer
authors.forename: Jesper Ø
authors.initials: JØ
authors.lastname: Hjortdal
authors.forename: Niels
authors.initials: N
authors.lastname: Ehlers
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008297:Male; D009216:Myopia / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D012449:Safety; D016896:Treatment Outcome; D014792:Visual Acuity