title: The epidemiology and modern management of traumatic hemorrhage: US and international perspectives.
abstract: Trauma is a worldwide problem, with severe and wide ranging consequences for individuals and society as a whole. Hemorrhage is a major contributor to the dilemma of traumatic injury and its care. In this article we describe the international epidemiology of traumatic injury, its causes and its consequences, and closely examine the role played by hemorrhage in producing traumatic morbidity and mortality. Emphasis is placed on defining situations in which traditional methods of hemorrhage control often fail. We then outline and discuss modern principles in the management of traumatic hemorrhage and explore developing changes in these areas. We conclude with a discussion of outcome measures for the injured patient within the context of the epidemiology of traumatic injury.
authors.affiliation: United States Army Institute of Surgical Research, Fort Sam Houston, Texas, USA. david.kauvar@amedd.army.mil
authors.forename: David S
authors.initials: DS
authors.lastname: Kauvar
authors.forename: Charles E
authors.initials: CE
authors.lastname: Wade
mesh_terms: D000293:Adolescent; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003422:Critical Care / Q000379:methods*; D004632:Emergency Medical Services; D014943:Global Health; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012771:Shock, Hemorrhagic / Q000150:complications* / Q000401:mortality / Q000628:therapy; D014481:United States / Q000453:epidemiology; D014947:Wounds and Injuries / Q000150:complications / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal