[A case of advanced hepatocellular carcinoma with tumor thrombus treated by transarterial chemoembolization therapy using cisplatin (CDDP) with DSM and SAP-MS].
A 78-year-old woman with advanced HCC had been treated by transarterial chemoembolization with epirubicin, however, tumor progression was not controlled and a tumor thrombus was found in the portal vein trunk. A new treatment method for transarterial chemoembolization using CDDP with DSM and SAP-MS was introduced. Marked regression of hepatic lesions and portal vein tumor thrombus was observed after two sessions. No adverse effect was found. The patient has been controlled without tumor recurrence and elevation of tumor marker for 14 months. A new treatment protocol will be useful for patients with far advanced hepatocellular carcinoma with portal vein tumor thrombus.
Hori
Shinichi
S
Gate Tower Institute for Image-Guided Therapy.
Sugiura
Takashi
T
Shirai
Yasuhiro
Y
Hiraishi
Kumiko
K
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D002945:Cisplatin / Q000008:administration & dosage*; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011108:Polymers / Q000008:administration & dosage; D011169:Portal Vein / Q000473:pathology; D013213:Starch / Q000008:administration & dosage*
D011108:Polymers; C083286:degradable starch microspheres; D013213:Starch; D002945:Cisplatin