title: [The effect of xantham gum on satiety status of obese patients after test meal].
abstract: Investigation of soluble fiber-xantham gum on hunger, satiety and epigastric fullness in obese subjects. 21 obese women: age 40.7 +/- 17, BMI 35.4 +/- 5.7 otherwise healthy, actually non dieting. Eating behavior was assessed by Three Factor Eating Behavior Questionnaire (TFEBQ) by evaluating eating restrain, dysinhibition and hunger. Satiety, hunger and epigastric fullness were assessed by visual analogue scale (VAS) and 7-point ratings scale before ingestion of test meal (ham sandwich--90 kcal) and in 20 min intervals during 2-hour observation. The study was done twice: with fiber and with placebo. Ingestion of test meal with drug and placebo causes statistical significant reduction in hunger and increase in satiety feelings in both groups. Afterwards during 2-hour observation the significant increase in hunger was observed. There were no differences in hunger, satiety and epigastric feelings between both groups. The significant positive correlation between third factor of TFEBQ (hunger) and BMI index was found. (r = 48, p < 0.05). 0.5 g of xanthan fiber with test meal didn't cause significant change of satiety. It is probably the effect of too low dose of xantham gum.
authors.affiliation: Katedry Patofizjologii Sla,skiej Akademii Medycznej, Katowicach.
authors.forename: Aleksander R
authors.initials: AR
authors.lastname: Zurakowski
authors.forename: Barbara
authors.initials: B
authors.lastname: Zahorska-Markiewicz
authors.forename: Magdalena
authors.initials: M
authors.lastname: Olszanecka-Glinianowicz
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Mucha
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D005503:Food Additives / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D008875:Middle Aged; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage / Q000494:pharmacology*; D012528:Satiety Response / Q000187:drug effects*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D005503:Food Additives; D011135:Polysaccharides, Bacterial; C002563:xanthan gum