title: Antiangiogenic therapy for a large splenic hemangioma.
abstract: Hemangiomas involving the spleen are rare and seldom symptomatic. Treatment options for large lesions usually consist of splenectomy, embolization, or both. Antiangiogenic treatment has not been reported previously as an effective alternative for this type of lesion. We report our experience of successfully using glucocorticoids in an infant with a large hemangioma of the spleen.
authors.affiliation: Department of Surgery, Division of Pediatric Surgery, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA. sislam@surgery.umsmed.edu
authors.forename: Saleem
authors.initials: S
authors.lastname: Islam
authors.forename: Erika A
authors.initials: EA
authors.lastname: Newman
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Strouse
authors.forename: James D
authors.initials: JD
authors.lastname: Geiger
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014463:Ultrasonography
chemical_list: D020533:Angiogenesis Inhibitors; D005938:Glucocorticoids; D011241:Prednisone