Isolation and sequence analysis of plasmid pNO33 in the epsilon-poly-L-lysine-producing actinomycete Streptomyces albulus IFO14147.
A high-molecular-size plasmid (37-kb), named pNO33, has been isolated from Streptomyces albulus IFO14147, a producer of epsilon-poly-L-lysine which exhibited antimicrobial activity. The sequence analysis of a 4.6-kb fragment in pNO33 revealed four putative open reading frames, one of which exhibited a significant homology to the bldB gene product involved in morphogenesis and antibiotic production by S. coelicolor.
Takagi
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H
Department of Bioscience, Fukui Prefectural University, 4-1-1 Kenjojima, Matsuoka-cho, Fukui 910-1195, Japan.
Hoshino
Y
Y
Nakamori
S
S
Inouye
S
S