title: [Digestive haemorrhage due to angiodysplasia in dialysis patients. Treatment with conjugated estrogens].
abstract: Gastrointestinal angiodysplasia is a very common cause of digestive hemorrhage among elderly patients with chronic renal insufficiency. Therapeutic possibilities are scarce, as well as information available. Here we present our experience with 8 cases of dialysis patients that were treated with conjugated estrogens because of digestive hemorrhage due to angiodysplasia. Dissapearance of bleeding was observed after the onset of estrogen therapy, with a significant decrease of blood transfusions. This type of non-invasive treatment can avoid aggressive therapeutic interventions in patients with a high prevalence of co-morbid conditions (old patients undergoing chronic dialysis).
authors.affiliation: Servicio de Nefrología, Hospital Doce de Octubre, Madrid.
authors.forename: M J
authors.initials: MJ
authors.lastname: Manzanera
authors.forename: E
authors.initials: E
authors.lastname: Gutiérrez
authors.forename: B
authors.initials: B
authors.lastname: Domínguez-Gil
authors.forename: J A
authors.initials: JA
authors.lastname: García
authors.forename: E
authors.initials: E
authors.lastname: González
authors.forename: M
authors.initials: M
authors.lastname: Praga
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000150:complications* / Q000175:diagnosis; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000627:therapeutic use*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008875:Middle Aged; D006435:Renal Dialysis; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D004966:Estrogens, Conjugated (USP)