title: Eyelid involvement in acanthosis nigricans: the importance of systemic screening.
abstract: A 53-year-old man presented with thickening and hyperpigmentation of the eyelids. After the diagnosis of acanthosis nigricans was made, further investigation of a possible underlying disorder, including biochemical and instrumental examinations, indicated the presence of glucose intolerance, which had been diagnosed 3 years after the clinical appearance of acanthosis nigricans. Eyelid involvement in acanthosis nigricans is rare. Ophthalmologists should be aware of the possibility that acanthosis nigricans can exist in the periocular area and perform a systemic assessment of the patient for the presence of an underlying condition.
authors.affiliation: Department of Ophthalmology, Izzet Baysal Medical Faculty, Bolu, Turkey. d_serin@yahoo.com
authors.forename: Didem
authors.initials: D
authors.lastname: Serin
authors.forename: Ali Haydar
authors.initials: AH
authors.lastname: Parlak
authors.forename: Gürsoy
authors.initials: G
authors.lastname: Alagöz
authors.forename: Cetin
authors.initials: C
authors.lastname: Boran
authors.forename: Nadir
authors.initials: N
authors.lastname: Göksügür
mesh_terms: D000052:Acanthosis Nigricans / Q000150:complications* / Q000473:pathology; D005141:Eyelid Diseases / Q000150:complications* / Q000473:pathology; D018149:Glucose Intolerance / Q000150:complications / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged