Pharmacogenomics-Potential applications to orthopedic practice.
Pharmacogenomics is developing at a rapid pace. Though ethical and financial considerations still exist, physicians should familiarize themselves with this evolving science.
Sutphin
Stephanie D
SD
University of Kentucky Chandler Medical Center, Lexington, KY 40536-0293, USA.
Smith
Kelly M
KM
D000925:Anticoagulants / Q000009:adverse effects / Q000378:metabolism; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics; D065729:Cytochrome P-450 CYP2C9; D004351:Drug Resistance / Q000235:genetics; D015894:Genome, Human; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D010597:Pharmacogenetics; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D013921:Thrombocytopenia / Q000209:etiology; D014859:Warfarin / Q000378:metabolism
D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases