Aspergillus oryzae palBory encodes a calpain-like protease: homology to Emericella nidulans PalB and conservation of functional regions.
We have cloned and sequenced genomic DNA of Aspergillus oryzae palBory, orthologue of Emericella nidulans palB, which encodes a calpain-like protease modulating a signal transduction pathway during alkaline adaptation. The deduced amino acid sequence of PalBory is 70.0% identical to PalB over its entire length. The regions with high similarity revealed possible domains important for their function. This is the first step towards understanding the alkaline adaptation mechanism of A. oryzae, which would be very useful in the fermentation industry.
Futai
E
E
Department of Molecular Biology, Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo 113-0032, Japan.
Sorimachi
H
H
Jeong
S Y
SY
Kitamoto
K
K
Ishiura
S
S
Suzuki
K
K