A supramolecular fluorescence sensor for pyrovanadate as a functional model of vanadium haloperoxidase.
A novel basket-shaped tris(pyrene guanidinium) receptor was synthesized which binds pyrovanadate and pyrophosphate with Ka > 107 M-1. The binding of both anions is associated with quenching of the excimer fluorescence of the pyrenes. The supramolecular vanadate complex catalyzes the bromination of activated C-H bonds and hence is an enzyme mimic of vanadium haloperoxidases.
Zhang
Xiao-An
XA
Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH- 4056 Basel, Switzerland.
Woggon
Wolf-D
WD
D015374:Biosensing Techniques / Q000379:methods*; D002384:Catalysis; D005453:Fluorescence; D046911:Macromolecular Substances / Q000737:chemistry*; D008760:Methylguanidine / Q000031:analogs & derivatives / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D010544:Peroxidases / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry; D017968:Vanadium Compounds / Q000737:chemistry*
D046911:Macromolecular Substances; D011721:Pyrenes; D017968:Vanadium Compounds; C507183:tris-(2-(N'-pyren-1-ylmethylguanidinium)ethyl)amine; D008760:Methylguanidine; D010544:Peroxidases; C026195:bromide peroxidase