Secondary signet-ring cell tumour of the prostate derived from a primary gastric malignancy.
Primary signet-ring cell carcinoma of the prostate is infrequent and even more so as secondary spread of this pathologic sub-type to the prostate. We describe the sixth reported case with a diagnosis of a secondary signet-ring cell tumour of the prostate secondary to a gastric cancer. Five years post-gastrectomy to resect signet-ring cell carcinoma, we detected a secondary intra-prostatic spread with urinary tract obstruction. The physical appearance of the tumour cells was similar to that of the previously-resected signet-cell carcinoma of the stomach. There were no metastases in other sites and the patient was treated with radiotherapy. When confronted with intra-prostatic signet-ring cell adenocarcinoma it is necessary to distinguish between primary and secondary aetiology since this would reflect in the choice of treatment and prognosis.
Cobo Dols
Manuel
M
Servicio de Oncología Médica, Hospital Regional Universitario Carlos Haya, Avda. Carlos Haya s/n, 29010 Málaga, Spain. mangel.cobo.sspa@juntadeandalucia.es
Muñoz Gallardo
Santiago
S
Peláez Angulo
José
J
Algarra García
Rosa
R
Fuente Lupiáñez
Carlos
C
Gil Calle
Silvia
S
Villar Chamorro
Ester
E
Montesa Pino
Alvaro
A
Alcaide García
Julia
J
Ales Díaz
Inmaculada
I
Gutiérrez Calderón
Vanesa
V
Carabante Ocón
Francisco
F
Benavides Orgaz
Manuel
M
D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D013274:Stomach Neoplasms / Q000473:pathology*