title: Disappearance of honeycomb opacity of Thiel-Behnke corneal dystrophy after Thygeson superficial punctate keratitis.
abstract: OBJECTIVE
  To present an unusual case in which the honeycomb opacities of Thiel-Behnke corneal dystrophy disappeared during a course of chronic Thygeson superficial punctate keratitis.
  
  
  METHODS
  A 29-year-old woman with a 5-year history of decreased visual acuity in both eyes had bilateral honeycomb-shaped corneal opacities, located mainly in the superficial central cornea. She was diagnosed as having Thiel-Behnke corneal dystrophy, which we confirmed genetically. During follow-up, her left eye was affected by chronic Thygeson superficial punctate keratitis, and the honeycomb opacity in this eye was noted to have disappeared.
  
  
  CONCLUSIONS
  We observed the dissolution of honeycomb-like corneal opacities in a patient with confirmed Thiel-Behnke corneal dystrophy after the patient subsequently contracted chronic Thygeson superficial punctate keratitis. We surmise that epithelial inflammation associated with Thygeson epithelial keratitis may play a role in dissolving the honeycomb opacities.
authors.affiliation: Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Japan. kobaya@kenroku.kanazawa-u.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Ijiri
authors.forename: Taeko
authors.initials: T
authors.lastname: Ohta
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Sugiyama
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000150:complications* / Q000473:pathology; D003318:Corneal Opacity / Q000209:etiology* / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D005469:Fluorometholone / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D007634:Keratitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D009883:Ophthalmic Solutions; D012075:Remission, Spontaneous
chemical_list: D000276:Adjuvants, Immunologic; D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D006820:Hyaluronic Acid; D005469:Fluorometholone