Diabetes and atherothrombotic disease: linked through inflammation?
Inflammation has been accepted as a key pathobiological mechanism in the development of cardiovascular disease, and acceptance is likely on its way for diabetes as well. Inflammation provides a linking mechanism between these two disorders, allowing them to influence each other in a wide variety of ways. Interventions aimed broadly at inflammation are likely to influence both diseases, and pathway-specific interventions may prove useful as well. The role of genetic variation remains poorly understood.
Tracy
Russell P
RP
Department of Pathology and Biochemistry, College of Medicine, University of Vermont, Colchester, Vermont 05446, USA. russell.tracy@uvm.edu
D001161:Arteriosclerosis / Q000276:immunology*; D003920:Diabetes Mellitus / Q000276:immunology*; D005342:Fibrinolysis / Q000276:immunology; D006487:Hemostasis / Q000276:immunology; D006801:Humans; D007249:Inflammation; D013927:Thrombosis / Q000276:immunology*