title: Changes in Doppler mitral inflow patterns during parabolic flight.
abstract: Aim of the study was to evaluate by transthoracic Doppler the alterations in mitral inflow velocity pattern caused by acute changes in loading conditions occurring during parabolic flights. Each parabola included normogravity (1 Gz, 1 min), mild hypergravity (1.8 Gz, 20 sec), microgravity (0 Gz, 24 sec) and mild hypergravity (1.8 Gz, 20 sec) phases. Pulsed-Doppler images were digitally acquired in 11 unmedicated subjects (46 +/- 5 years), in standing upright position and supine resting. Doppler profiles were semi-automatically traced and inflow parameters extracted and averaged onto three consecutive beats. Only in standing position, significant alterations during microgravity (p<0.05) were noted in several parameters.
authors.affiliation: Biomedical Eng. Dept., Politecnico di Milano, Milano, Italy. caiani@biomed.polimi.it
authors.forename: E G
authors.initials: EG
authors.lastname: Caiani
authors.forename: G
authors.initials: G
authors.lastname: Asquer
authors.forename: M
authors.initials: M
authors.lastname: Turiel
authors.forename: O
authors.initials: O
authors.lastname: Bailliart
authors.forename: B
authors.initials: B
authors.lastname: Cholley
authors.forename: A
authors.initials: A
authors.lastname: Capderou
authors.forename: P
authors.initials: P
authors.lastname: Vaida
mesh_terms: D000328:Adult; D015150:Echocardiography, Doppler; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D018471:Hypergravity; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D011187:Posture / Q000502:physiology; D013026:Space Flight; D016683:Supine Position; D016277:Ventricular Function, Left / Q000502:physiology*; D014893:Weightlessness