title: All silent on the transcription front.
abstract: Peptide nucleic acid (PNA) or RNA directed against the genomic DNA sequence around the transcription start site effectively knock down the expression of the targeted gene and make for an effective addition to the arsenal of gene silencing methods.
authors.forename: Nicole
authors.initials: N
authors.lastname: Rusk
mesh_terms: D020868:Gene Silencing; D018390:Gene Targeting / Q000379:methods; D009841:Oligonucleotides / Q000235:genetics; D020135:Peptide Nucleic Acids / Q000737:chemistry / Q000235:genetics; D012330:RNA, Double-Stranded / Q000737:chemistry / Q000235:genetics; D024363:Transcription Initiation Site; D014158:Transcription, Genetic
chemical_list: D009841:Oligonucleotides; D020135:Peptide Nucleic Acids; D012330:RNA, Double-Stranded