title: [Effectiveness of kampo medicine gorei-san-ryo for chronic subdural hematoma in very elderly patients].
abstract: Chronic subdural hematoma (CSDH) is mainly a disease of the elderly. Widespread use of CT and MRI has resulted in the discovery of CSDH cases with no or minimum symptoms in the elderly. Treatment is by surgical evacuation, although small hematoma may resolve spontaneously. Treatment of CSDH in elderly patients of more than 80 years of age with minimum symptoms is still undetermined. Many conservative treatments such as those with steroids and diuretics have been reported with some good results. Conservative treatment cannot become the procedure of choice for fear of side effects. We report successful treatment for CSDH cases among the very elderly with a Kampo medicine (Japanese traditional herbal medicine). Among a total eleven cases, four were recurrent after surgical evacuation and seven showed significant hematoma with minimal symptoms. Gorei-san-ryo, a Kampo medicine, was administered for 3 to 12 months. Some cases showed rapid hematoma resolution after administration. Only one of them required subsequent surgical intervention. This conservative treatment with Kampo medicine for CSDH may be a potential alternative to surgery especially for the elderly.
authors.affiliation: Department of Neurosurgery, Yao Tokushukai General Hospital, Japan. muramasa36@hotmail.com
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Muramatsu
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hanabusa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D020200:Hematoma, Subdural, Chronic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D020835:Medicine, Kampo
chemical_list: D004365:Drugs, Chinese Herbal; C111129:gorei-san