title: Suzuki-Miyaura cross-coupling of benzylic phosphates with arylboronic acids.
abstract: [reaction: see text] Suzuki-Miyaura cross-coupling of benzylic phosphates with arylboronic acids was investigated. Optimum conditions employed the simple catalytic system of palladium(II) acetate (1 mol %) and triphenylphosphine (4 mol %) with either potassium phosphate or potassium carbonate as the base and toluene as the solvent at 90 degrees C. Using the developed conditions, a series of structurally diverse diarylmethanes were prepared.
authors.affiliation: Department of Process Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA. mark_mclaughlin@merck.com
authors.forename: Mark
authors.initials: M
authors.lastname: McLaughlin
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry*
chemical_list: D001555:Benzene Derivatives; D001897:Boronic Acids; D010710:Phosphates; D010165:Palladium