title: Atrial fibrillation: basic and clinical research at the Montreal Heart Institute.
abstract: The present article reviews pertinent contributions from the Montreal Heart Institute, Montreal, Quebec, to the understanding of the mechanisms and treatment of atrial fibrillation. The article discusses the usefulness of anticoagulant therapy, antiarrhythmic drug therapy for sinus rhythm maintenance, the electrophysiological basis of atrial fibrillation and the investigation of new energy sources for catheter ablation. Future directions at the Montreal Heart Institute are also briefly addressed.
authors.affiliation: Department of Medicine and Research Centre, Montreal Heart Institute, Faculty of Medicine, University of Montreal, Quebec. d-roy@icm-mhi.com
authors.forename: Denis
authors.initials: D
authors.lastname: Roy
authors.forename: Mario
authors.initials: M
authors.lastname: Talajic
authors.forename: Marc
authors.initials: M
authors.lastname: Dubuc
authors.forename: Bernard
authors.initials: B
authors.lastname: Thibault
authors.forename: Peter G
authors.initials: PG
authors.lastname: Guerra
authors.forename: Laurent
authors.initials: L
authors.lastname: Macle
authors.forename: Pierre
authors.initials: P
authors.lastname: Gagné
authors.forename: Paul
authors.initials: P
authors.lastname: Khairy
authors.forename: Stanley
authors.initials: S
authors.lastname: Nattel
mesh_terms: D000047:Academies and Institutes; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000503:physiopathology / Q000628:therapy; D035843:Biomedical Research / Q000639:trends; D002170:Canada; D006328:Cardiac Catheterization; D003452:Cryosurgery; D022062:Electrophysiologic Techniques, Cardiac; D004617:Embolism / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D006339:Heart Rate / Q000187:drug effects; D006801:Humans
chemical_list: D000889:Anti-Arrhythmia Agents; D000925:Anticoagulants