title: Enantioface-selective palladium-catalyzed silaboration of allenes via double asymmetric induction.
abstract: Enantioenriched beta-borylallylsilanes were synthesized by palladium-catalyzed enantioface-selective addition of the silicon-boron bond to terminal allenes using a palladium catalyst possessing a chiral monodentate phosphine ligand. Use of a silylborane bearing a chiral auxiliary on the boron atom was beneficial to gain enantioface selectivities as high as 96% de.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, and PRESTO, Japan Science and Technology Corporation (JST), Katsura, Nishikyo-ku, Kyoto 615-8510, Japan. suginome@sbchem.kyoto-u.ac.jp
authors.forename: Michinori
authors.initials: M
authors.lastname: Suginome
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Ohmura
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Shin'ichirou
authors.initials: S
authors.lastname: Mitani
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Ito
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami