title: Enzymatic synthesis of sugar amino acid esters in organic solvents.
abstract: The enzymatic synthesis of sugar amino acid esters in polar organic solvents was studied using surfactant-enzyme complexes, which were previously developed as a highly active biocatalyst in organic solvents. Of the several lipases and proteases tested, the surfactant-subtilisin complex exhibited the highest synthetic activity in pyridine. The amino acid was regioselectively introduced at the C-6 position of d-glucose and at the C-6' of maltose by the surfactant-subtilisin complex. This biocatalyst was found to effectively catalyze the synthesis of various sugar amino acid esters in a polar organic solvent.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Maruyama
authors.forename: Shin-Ichiro
authors.initials: S
authors.lastname: Nagasawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Goto