title: Substituent effects on thermal decolorization rates of bisbenzospiropyrans.
abstract: [reaction: see text] A novel application of photochromic molecules is to mimic physiological oscillatory calcium signals by reversibly binding and releasing calcium ions in response to light. Substituent changes on the largely unexplored photochromic bisbenzospiropyran scaffold led to significant changes in thermal fading rates in several organic solvents. Excellent correlations have been found between fading rates and empirical Hammett constants as well as calculated ground-state energies. These correlations can be used to improve scaffold design.
authors.affiliation: The Department of Chemistry and Biochemistry, California State University, Los Angeles, 90032, USA.
authors.forename: Nina T
authors.initials: NT
authors.lastname: Lu
authors.forename: Vi N
authors.initials: VN
authors.lastname: Nguyen
authors.forename: Satish
authors.initials: S
authors.lastname: Kumar
authors.forename: Alison
authors.initials: A
authors.lastname: McCurdy
mesh_terms: D001578:Benzopyrans / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry; D015394:Molecular Structure; D010777:Photochemistry; D012997:Solvents; D013057:Spectrum Analysis; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D001578:Benzopyrans; D007211:Indoles; D012997:Solvents; C014389:1-(beta-carboxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline- 2,2'-2H-benzopyran); C057812:indoline