Drug-resistant salmonellosis.
After the development of plasmid-mediated resistance against first-line drugs, the emergence of chromosomally-mediated quinolone resistance in typhoid fever has become a major concern. Quinolone insensitivity and treatment failures with ciprofloxacin are being increasingly reported. However, third generation cephalosporins have come as a saviour. To overcome fluoroquinolone insensitivity, higher doses with longer duration of treatment is recommended. Moreover, return of chloramphenicol and furazolidone sensitivity shown by different studies is a welcome observation.
Kundu
Arup Kumar
AK
Department of Medicine, NRS Medical College, Kolkata.
D002511:Cephalosporins / Q000627:therapeutic use; D018432:Drug Resistance, Multiple; D006801:Humans; D012480:Salmonella Infections / Q000188:drug therapy*; D014435:Typhoid Fever / Q000188:drug therapy
D002511:Cephalosporins