title: [A case of advanced gastric cancer with obstructive jaundice that responded to TS-1/CPT-11 combination therapy after percutaneous transhepatic cholangio drainage].
abstract: TS-1/CPT-11 combination therapy was carried out in a case of advanced gastric cancer with liver and lymph node metastases and obstructive jaundice after percutaneous transhepatic cholangio drainage (PTCD). Regression of the primary carcinoma and reduction in size of metastases were observed. Grade 1 fatigue and grade 2 neutropenia were noted as adverse reactions to the treatment. TS-1/CPT-11 combination therapy was useful in this case of advanced gastric cancer with liver and lymph node metastases.
authors.affiliation: Dept. of Medical Oncology, Misawa City Hospital.
authors.forename: Kohei
authors.initials: K
authors.lastname: Shitara
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ishiguro
authors.forename: Masaki
authors.initials: M
authors.lastname: Munakata
authors.forename: Yuh
authors.initials: Y
authors.lastname: Sakata
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Mizuno
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Wada
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001659:Biliary Tract; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D003131:Combined Modality Therapy; D004322:Drainage / Q000379:methods*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005773:Gastroscopy; D006801:Humans; D000077146:Irinotecan; D041781:Jaundice, Obstructive / Q000150:complications / Q000628:therapy*; D008113:Liver Neoplasms / Q000556:secondary; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000077146:Irinotecan; D002166:Camptothecin