Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers.
[reaction: see text] A family of dendritic amphiphiles were synthesized from the natural metabolites of glycerol, succinic acid, and myristic acid. The surfaces of these dendrimers display different numbers of alkyl chains and carboxylic acids, varying the hydrophobic-to-hydrophilic ratio over a relatively broad range. In solution these dendritic amphiphiles form supramolecular structures, and these aggregates have been characterized by light microscopy, transmission electron microscopy, and tensiometry. These aggregates can entrap the hydrophobic species pyrene.
Luman
Nathanael R
NR
Department of Chemistry, Metcalf Center for Science and Engineering, Boston University, Massachusetts 02215, USA.
Grinstaff
Mark W
MW
D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry*; D005990:Glycerol / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D019814:Myristic Acid / Q000737:chemistry; D019802:Succinic Acid / Q000737:chemistry; D013499:Surface Properties; D013501:Surface-Active Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D050091:Dendrimers; D013501:Surface-Active Agents; D014867:Water; D019814:Myristic Acid; D019802:Succinic Acid; D005990:Glycerol