[Malaria prophylaxis for long-term travellers and expatriates].
Long-term travellers and expatriates are often non-compliant with malaria chemoprophylaxis due to a gradual neglect of the malaria risk combined with an unwillingness to take drugs for prolonged periods. The available regimes either have limited efficacy or are hampered by side effects, fears, cost and lack of data on long-term use. In order to prevent the dire consequences of malaria, we suggest tailoring the antimalarial strategy to the individual traveller. This requires balancing the risk of getting malaria, based on local transmission patterns, mosquito control and other factors, with the traveller's access to medical care and the options for chemoprophylaxis, the use of which in some cases may be limited to the rainy season or periods of travel to high-risk areas.
Kurtzhals
Jørgen A L
JA
H:S Rigshospitalet, Klinisk Mikrobiologisk Afdeling, Center for Medicinsk Parasitologi, og Statens Serum Institut, Afdeling for Bakteriologi, Mykologi og Parasitologi, Parasitologisk Laboratorium, København. jkcmp@rh.dk
Vestergaard
Lasse S
LS
D000962:Antimalarials / Q000008:administration & dosage* / Q000009:adverse effects; D053626:Atovaquone; D002738:Chloroquine / Q000008:administration & dosage / Q000009:adverse effects; D003376:Counseling; D004318:Doxycycline / Q000008:administration & dosage / Q000009:adverse effects; D004338:Drug Combinations; D006801:Humans; D007299:Insect Bites and Stings / Q000517:prevention & control; D008288:Malaria / Q000517:prevention & control*; D015767:Mefloquine / Q000008:administration & dosage / Q000009:adverse effects; D009032:Mosquito Control; D009285:Naphthoquinones / Q000008:administration & dosage / Q000009:adverse effects; D002727:Proguanil / Q000008:administration & dosage / Q000009:adverse effects; D018570:Risk Assessment; D012307:Risk Factors; D014195:Travel
D000962:Antimalarials; D004338:Drug Combinations; D009285:Naphthoquinones; C109496:atovaquone, proguanil drug combination; D002738:Chloroquine; D004318:Doxycycline; D002727:Proguanil; D015767:Mefloquine; D053626:Atovaquone