Development of new dosimetry using extended DNA fibers.
We applied fluorescent microscopy to monitor the damage of DNA upon exposure to gamma radiation. Our developed dosimetry demonstrated that the number of breaks in DNA is proportional to the dose of the irradiation but is not dependent on dose rate of the irradiation and the GC content of DNA.
Matsunaga
Sachihiro
S
Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Ohshio
Kazutaka
K
Harada
Erimu
E
Fujiwara
Shinsuke
S
Uchiyama
Susumu
S
Fukui
Kiichi
K