Effect of capsule circulation velocity on production of L-lysine by encapsulated Corynebacterium glutamicum in an airlift bioreactor.
The effect of capsule circulation velocity and volumetric oxygen transfer coefficient on the production of L-lysine by encapsulated Corynebacterium glutamicum in an airlift bioreactor has been evaluated. A larger oxygen supply in the airlift bioreactor caused a more than 58% increase in L-lysine productivity compared to that in a shaking flask incubator. The quantity of L-lysine produced during 5 h of cultivation in the airlift bioreactor was suggested to increase with increasing circulation velocity of the capsule in the bioreactor rather than with an increase in volumetric oxygen transfer coefficient.
Park
J K
JK
Department of Chemical Engineering, Kyungpook National University, Taegu 702-701, Korea. parkjk@kyungpook.ac.kr
Jeong
G S
GS