A case of Reye syndrome with rotavirus infection accompanied with high cytokines.
We report on a 23-month-old boy with a rare complication of rotavirus gastroenteritis. He was diagnosed as acute encephalopathy with DIC accompanied with high levels of cytokines. The liver pathology also revealed mild infiltration and fatty changes. He was suspected to be suffering from a cytokine storm followed by Reye syndrome.
Ioi
Hiroaki
H
Department of Paediatrics, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Kawashima
Hisashi
H
Nishimata
Shigeo
S
Watanabe
Yoshiaki
Y
Yamanaka
Gaku
G
Kashiwagi
Yasuyo
Y
Yamada
Naoto
N
Tsuyuki
Kazumitsu
K
Takekuma
Kouji
K
Hoshika
Akinori
A
Kage
Masayoshi
M
D000927:Anticonvulsants / Q000627:therapeutic use; D001707:Biopsy, Needle; D016207:Cytokines / Q000097:blood*; D003937:Diagnosis, Differential; D005759:Gastroenteritis / Q000150:complications* / Q000175:diagnosis / Q000821:virology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007223:Infant; D008099:Liver / Q000473:pathology; D008297:Male; D008874:Midazolam / Q000627:therapeutic use; D008928:Mitochondria / Q000473:pathology; D012121:Respiration, Artificial; D012202:Reye Syndrome / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D012400:Rotavirus Infections / Q000150:complications* / Q000175:diagnosis; D013874:Thiopental / Q000627:therapeutic use; D013997:Time Factors
D000927:Anticonvulsants; D016207:Cytokines; D006993:Hypnotics and Sedatives; D013874:Thiopental; D008874:Midazolam