title: A thieno-2H-chromene alpha-amino acid derivative: synthesis and photochromic properties.
abstract: [structure: see text] A new photochromic thieno-2H-chromene alpha-amino acid derivative was prepared by C-N palladium-catalyzed cross-coupling of a bromothieno-2H-chromene with the aminated aromatic side chain of the methyl ester of a N,N-diprotected amino acid. Its good photochromic properties demonstrated by flash photolysis and continuous irradiation indicate a possible application in ophthalmic lenses. It may also be inserted into peptides to give photoinduced reversible structural changes.
authors.affiliation: Departamento de Química, Universidade do Minho, Campus de Gualtar, Braga, Portugal. mjrpq@quimica.uminho.pt
authors.forename: Maria-João R P
authors.initials: MJ
authors.lastname: Queiroz
authors.forename: Ana S
authors.initials: AS
authors.lastname: Abreu
authors.forename: Paula M T
authors.initials: PM
authors.lastname: Ferreira
authors.forename: M Manuel
authors.initials: MM
authors.lastname: Oliveira
authors.forename: Roger
authors.initials: R
authors.lastname: Dubest
authors.forename: Jean
authors.initials: J
authors.lastname: Aubard
authors.forename: André
authors.initials: A
authors.lastname: Samat