title: Targeting toxic proteins for turnover.
authors.forename: Albert R
authors.initials: AR
authors.lastname: La Spada
authors.forename: Patrick
authors.initials: P
authors.lastname: Weydt
mesh_terms: D000818:Animals; D016227:Benzoquinones; D004195:Disease Models, Animal; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D047029:Lactams, Macrocyclic; D051379:Mice; D009134:Muscular Atrophy, Spinal / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology*; D010455:Peptides / Q000235:genetics; D011944:Receptors, Androgen / Q000235:genetics* / Q000378:metabolism*; D017828:Rifabutin / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D019680:Trinucleotide Repeat Expansion / Q000235:genetics
chemical_list: D016227:Benzoquinones; D018841:HSP90 Heat-Shock Proteins; D047029:Lactams, Macrocyclic; D010455:Peptides; D011944:Receptors, Androgen; D017828:Rifabutin; C097188:polyglutamine; C112765:tanespimycin