title: Repeated intensification of lower urinary tract symptoms in the patient with benign prostatic hyperplasia during bisoprolol treatment.
abstract: A case of a 60-year-old male patient, suffering from benign prostatic hyperplasia (BPH), with deterioration of lower urinary tract symptoms (LUTS) during antihypertensive treatment with bisoprolol was presented. Discontinuation of beta-blocker resulted in giving a relief whereas the resumption of its use caused repeated deterioration. Bisoprolol deteriorated lower urinary tract symptoms in patient with benign prostatic hyperplasia. Increase of lower urinary tract symptoms caused by beta-blockers can be more significant in elderly men.
authors.affiliation: 1st Clinic of Internal Diseases and Acute Poisonings, Medical University of Gdańsk, Poland. jsanand@amedec.amg.gda.pl
authors.forename: Jacek
authors.initials: J
authors.lastname: Sein Anand
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Chodorowski
authors.forename: Adam
authors.initials: A
authors.lastname: Hajduk
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D017298:Bisoprolol / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000188:drug therapy* / Q000503:physiopathology; D014551:Urinary Tract / Q000187:drug effects; D014555:Urination Disorders / Q000139:chemically induced* / Q000628:therapy
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D017298:Bisoprolol