title: Palladium-catalyzed coupling reactions of bromothiophenes at the C-H bond adjacent to the sulfur atom with a new activator system, AgNO3/KF.
abstract: [reaction: see text] Bromothiophene derivatives react with aryl iodides catalyzed by a palladium complex in the presence of a silver(I) nitrate/potassium fluoride system to induce coupling at the C-H bond, while the carbon-bromine bond is intact. The produced coupling product bearing the C-Br bond allows further palladium-catalyzed C-C bond-forming reactions in reasonable yields.
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sugie
authors.forename: Masabumi
authors.initials: M
authors.lastname: Takahashi
authors.forename: Kentaro
authors.initials: K
authors.lastname: Masui
authors.forename: Atsunori
authors.initials: A
authors.lastname: Mori