title: Transfusion-related acute lung injury.
abstract: OBJECTIVE
  Transfusion-related acute lung injury is an uncommon complication of blood transfusion typically manifested by shortness of breath, fever, and hypotension. Transfusion-related acute lung injury is an important cause of transfusion-related morbidity and mortality.
  
  
  RESULTS
  Much about the pathogenesis, treatment, and prevention of transfusion-related acute lung injury is poorly understood or is controversial. There is increasing recognition that transfusion-related acute lung injury is an important clinical syndrome, causing most transfusion-related deaths.
  
  
  CONCLUSIONS
  In this report, what is known about transfusion-related acute lung injury is summarized with particular emphasis on recent studies. Some of the areas in which knowledge and/or consensus are currently lacking are identified.
authors.affiliation: Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Webert
authors.forename: Morris A
authors.initials: MA
authors.lastname: Blajchman
mesh_terms: D006801:Humans; D011654:Pulmonary Edema / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D012128:Respiratory Distress Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D065227:Transfusion Reaction