Tuneable asymmetric copper-catalysed allylic amination and oxidation reactions.
Asymmetric allylic amination or oxidation can be achieved by reaction of an alkene with a peroxycarbamate catalysed by a chiral copper bis-oxazoline complex, and the reaction can be tuned to give either the amination or oxidation product by reagent choice.
Clark
J Stephen
JS
School of Chemistry, University of Nottingham, University Park, Nottingham, UKNG7 2RD. j.s.clark@nottingham.ac.uk
Roche
Caroline
C
D000475:Alkenes / Q000737:chemistry; D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D002219:Carbamates / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000475:Alkenes; D000498:Allyl Compounds; D002219:Carbamates; D008024:Ligands; D010080:Oxazoles; D003300:Copper