title: The renal epidemiology and information network (REIN): a new registry for end-stage renal disease in France.
abstract: The French Renal Epidemiology and Information Network (REIN) registry began in 2002 to provide a tool for public health decision support, evaluation and research related to renal replacement therapies (RRT) for end-stage renal disease (ESRD). It relies on a network of nephrologists, epidemiologists, patients and public health representatives, coordinated regionally and nationally. Continuous registration covers all dialysis and transplanted patients. In 2003, 2070 patients started RRT, 7854 were on dialysis and 7294 lived with a functioning graft in seven regions (with a population of 16.5 million people). The overall crude annual incidence rate of RRT for ESRD was 123 per million population (p.m.p.) with significant differences in age-adjusted rates across regions, from 84 [95% confidence interval (CI): 74-94] to 155 [138-172] p.m.p. The principal causes of ESRD were hypertension (21%) and diabetic (20%) nephropathies. Initial treatment for ESRD was peritoneal dialysis for 15% of patients and a pre-emptive graft for 3%. The one-year survival rate was 81% [79-83] in the cohort of 2002-2003 incident patients. As of December 31, 2003, the overall crude prevalence was 898 [884-913] p.m.p, with 5% of patients receiving peritoneal dialysis, 47% on haemodialysis and 48% with a functioning graft. The experience in these seven regions over these two years clearly shows the feasibility of the REIN registry, which is progressively expanding to cover the entire country.
authors.affiliation: REIN Registry, Agence de la biomédecine, La Plaine Saint Denis. cecile.couchoud@biomedecine.fr
authors.forename: Cécile
authors.initials: C
authors.lastname: Couchoud
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Stengel
authors.forename: Paul
authors.initials: P
authors.lastname: Landais
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Aldigier
authors.forename: François
authors.initials: F
authors.lastname: de Cornelissen
authors.forename: Christian
authors.initials: C
authors.lastname: Dabot
authors.forename: Hervé
authors.initials: H
authors.lastname: Maheut
authors.forename: Véronique
authors.initials: V
authors.lastname: Joyeux
authors.forename: Michèle
authors.initials: M
authors.lastname: Kessler
authors.forename: Michel
authors.initials: M
authors.lastname: Labeeuw
authors.forename: Hubert
authors.initials: H
authors.lastname: Isnard
authors.forename: Christian
authors.initials: C
authors.lastname: Jacquelinet
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012042:Registries