title: Animal models of leptomeningeal cancer.
abstract: Animal models are a critical tool for our understanding of pathogenic mechanisms and the development of therapeutic strategies. Since the 1970's, numerous syngeneic and allogeneic rodent models of leptomeningeal cancer have been developed; in this chapter, we present representative models and discuss their clinical and translational implications.
authors.affiliation: University of Illinois at Chicago, Chicago, IL 60612, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Raja
authors.forename: Herbert H
authors.initials: HH
authors.lastname: Engelhard
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology*; D051379:Mice; D009368:Neoplasm Transplantation; D051381:Rats; D014183:Transplantation, Heterologous