Vaginal epithelial cell anti-Candida albicans activity is associated with protection against symptomatic vaginal candidiasis.
Vaginal epithelial cell (VEC) anti-Candida albicans activity, despite being measured in vitro, is considered an innate host defense mechanism. This was supported further by the fact that women protected from symptomatic infection following a live intravaginal Candida challenge had increased VEC anti-Candida activity compared to those who acquired a symptomatic infection.
Barousse
Melissa M
MM
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Espinosa
Terri
T
Dunlap
Kathleen
K
Fidel
Paul L
PL
D000328:Adult; D002181:Candidiasis, Vulvovaginal / Q000276:immunology* / Q000517:prevention & control*; D004847:Epithelial Cells / Q000276:immunology*; D005260:Female; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D008875:Middle Aged; D014621:Vagina / Q000166:cytology*