Therapeutic approaches to Chlamydia infections.
Chlamydia trachomatis ocular and urogenital infections represent major public health problems, whereas Chlamydophila pneumoniae is a common aetiological agent of community-acquired pneumonia. The obligate intracellular lifestyle of these established pathogens poses challenges to both their diagnosis and treatment. Tetracyclines, macrolides and quinolones remain the antimicrobials of choice for the treatment of infections due to Chlamydiaceae.
Senn
Laurence
L
Department of Internal Medicine, University Hospital, Lausanne, Switzerland.
Hammerschlag
Margaret R
MR
Greub
Gilbert
G
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000187:drug effects* / Q000302:isolation & purification; D016993:Chlamydophila pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D003235:Conjunctivitis, Inclusion / Q000188:drug therapy* / Q000382:microbiology; D052776:Female Urogenital Diseases / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology / Q000627:therapeutic use; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D017410:Practice Guidelines as Topic; D015363:Quinolones / Q000494:pharmacology / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D013754:Tetracyclines / Q000494:pharmacology / Q000627:therapeutic use; D014141:Trachoma / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D018942:Macrolides; D015363:Quinolones; D013754:Tetracyclines