title: In vivo comparative wear study of traditional and highly cross-linked polyethylene in total hip arthroplasty.
abstract: In this study, we compare the in vivo wear performance of electron beam-irradiated, postirradiation-melted, highly cross-linked polyethylene (HXLPE) and traditional UHMWPE via the Martell method. Seventy hips with HXLPE performed at the Massachusetts General Hospital had 138 radiograph pairs for wear analysis and a 31.2-month average follow-up (range, 24-44 months). An age-matched, sex-matched, and body mass index-matched subgroup of 111 hips with 214 acceptable radiograph pairs and a 4-year follow-up from our previously published study on traditional polyethylene performed at Rush-Presbyterian-St. Luke's Medical Center served as a control group. Martell wear analysis was performed for each group. Overall and steady-state wear rates were compared via a specialized t test. The steady-state wear in the HXLPE arm was observed after 2.0 years, was 0.007 mm/y, and was significantly less than the steady-state wear in the traditional arm (0.174 mm/y) (P = .003). Highly cross-linked polyethylene penetration rate was not affected by sex, age, activity, or body mass index by Mann-Whitney analysis.
authors.affiliation: Section of Orthopaedic Surgery and Rehabilitative Medicine, The University of Chicago Medical Center, IL 60637, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Manning
authors.forename: P P
authors.initials: PP
authors.lastname: Chiang
authors.forename: J M
authors.initials: JM
authors.lastname: Martell
authors.forename: J O
authors.initials: JO
authors.lastname: Galante
authors.forename: W H
authors.initials: WH
authors.lastname: Harris
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D020959:Polyethylene; D011474:Prosthesis Design; D011475:Prosthesis Failure
chemical_list: D020959:Polyethylene