title: [Stromal bone formation by lung adenocarcinoma].
abstract: We report a case of lung adenocarcinoma with stromal bone formation. A 73-year-old woman was incidentally found to have a coin lesion in the left lower lung field on a chest roentgenogram and computed tomography showed a nodular lesion containing a few coarse high density areas in the left lower lobe. Since transbronchial cytology revealed adenocarcinoma, left lower lobectomy was performed. Histologically, the tumor was a papillary-tubular adenocarcinoma, and fragments of osseous tissue were found within abundant fibrous stroma. Bone formation in primary lung adenocarcinoma is a very rare condition, and only 7 other cases have been reported in the literature.
authors.affiliation: Department of Surgery, Kyoto First Red Cross Hospital.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ueshima
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kurioka
authors.forename: Ryouji
authors.initials: R
authors.lastname: Yamada
authors.forename: Chieko
authors.initials: C
authors.lastname: Takumi
authors.forename: Noriya
authors.initials: N
authors.lastname: Hiraoka
authors.forename: Seiko
authors.initials: S
authors.lastname: Ono
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D010012:Osteogenesis; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed