A novel inhibitory effect of D-allose on production of reactive oxygen species from neutrophils.
The rare sugar D-allose produced from D-psicose using an immobilized L-rhamnose isomerase bioreactor was shown to have weak scavenging activity toward reactive oxygen species (ROS) and potent inhibitory effect on production of ROS from stimulated neutrophils. These findings may have important implications in understanding the ameliorative effect of D-allose in transplantation and ischemia/reperfusion injury.
Murata
Akiko
A
Department of Ophthalmology, Kagawa Medical University, 1750-1 Ikenobe, Miki-cho, Kagawa 761-0793, Japan.
Sekiya
Keizo
K
Watanabe
Yasuo
Y
Yamaguchi
Fuminori
F
Hatano
Naoya
N
Izumori
Ken
K
Tokuda
Masaaki
M