title: Ultrafast MRI in the prenatal diagnosis of Bourneville's tuberous sclerosis.
abstract: The purpose of this report is to highlight the utility of prenatal MRI as an adjunctive imaging modality in the diagnosis and prognosis of Tuberous Sclerosis (TS) (Bourneville's disease). We report a case of TS detected in utero at 30 weeks gestation. A routine ultrasonography at 26 weeks in a 28-year-old primigravida was followed by an ultrafast MRI examination at 30 weeks gestation. Ultrasound raised the possibility of TS based on the detection of multiple cardiac rhabdomyomas. Fetal MRI, subsequently performed, showed the presence of cortical tubers and subependymal nodules establishing the diagnosis. Fetal MRI in the appropriate clinical setting can be potentially invaluable and can have important prognostic implications.
authors.affiliation: Department of Magnetic Resonance Imaging, Dr. Balabhai Nanavati Hospital, Vile Parle, Mumbai, India. paritoshkhanna@hotmail.com
authors.forename: P C
authors.initials: PC
authors.lastname: Khanna
authors.forename: S
authors.initials: S
authors.lastname: Godinho
authors.forename: S A
authors.initials: SA
authors.lastname: Pungavkar
authors.forename: D P
authors.initials: DP
authors.lastname: Patkar
mesh_terms: D000328:Adult; D001344:Autopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014402:Tuberous Sclerosis / Q000175:diagnosis* / Q000196:embryology*