Iterative, orthogonal strategy for oligosaccharide synthesis based on the regioselective glycosylation of polyol acceptors with partially unprotected n-pentenyl-orthoesters: further evidence for reciprocal donor acceptor selectivity (RDAS).
An efficient iterative, orthogonal protocol based on the regioselective glycosyl coupling of D-mannose polyols with, partially unprotected, n-pentenyl orthoester donors permits the synthesis of linear and branched oligosaccharides with minimal protecting group tampering.
López
J Cristóbal
JC
Instituto de Química Orgánica General, CSIC, Juan de la Cierva 3, 28006, Madrid, Spain. clopez@iqog.csic.es
Agocs
Attila
A
Uriel
Clara
C
Gómez
Ana M
AM
Fraser-Reid
Bert
B