title: Effect of praseodymium(III) on zinc(II) species in human interstitial fluid.
abstract: A multiphase model of metal ion species in human interstitial fluid was constructed under physiological conditions. The effect of Pr(III) on Zn(II) species was studied. At the normal conditions, Zn(II) species mainly distribute in [Zn(HSA)], [Zn(IgG)], and [Zn(Cys)(2)H](+). With the Pr(III) level increased, the apparent competition of Pr(III) for ligands lead to the redistribution of Zn(II) species.
authors.affiliation: Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, People's Republic of China.
authors.forename: Haiyuan
authors.initials: H
authors.lastname: Zhang
authors.forename: Jinping
authors.initials: J
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Lu
authors.forename: Kuiyue
authors.initials: K
authors.lastname: Yang
authors.forename: Chunji
authors.initials: C
authors.lastname: Niu
mesh_terms: D001667:Binding, Competitive; D003198:Computer Simulation; D045604:Extracellular Fluid / Q000378:metabolism*; D008024:Ligands; D008954:Models, Biological; D011221:Praseodymium / Q000378:metabolism* / Q000494:pharmacology; D015032:Zinc / Q000378:metabolism*
chemical_list: D008024:Ligands; D015032:Zinc; D011221:Praseodymium