title: Single-stage anterior autogenous bone grafting and instrumentation in the surgical management of spinal tuberculosis.
abstract: METHODS
  Results of single-stage anterior autogenous bone grafting and instrumentation for spinal tuberculosis were reported.
  
  
  OBJECTIVE
  To determine the efficacy of anterior instrumentation following radical debridement and autogenous bone grafting in patients with spinal tuberculosis over a 3-year period at a single institution.
  
  
  BACKGROUND
  Patients with spinal tuberculosis have been not always successfully treated by radical debridement and bone grafting with or without supplementary posterior instrumentation and fusion, although most surgeons use posterior instrumentation to support anterior strut grafts.
  
  
  METHODS
  In this prospective study, the authors evaluated 39 patients (22 male and 17 female; average age, 48 years) with spinal tuberculosis, who underwent single-stage anterior radical debridement, autogenous bone grafting, and instrumentation. The average follow-up period was 39.9 months (range, 30-54 months).
  
  
  RESULTS
  A solid fusion was achieved in all cases; there were 2 cases of draining fistula formation. Of all 28 patients with preoperative kyphosis, the deformity was corrected from an average of 13.5 degrees on admission to an average of 1.9 degrees after surgery. No significant loss of deformity correction was noted in these patients. There was no other recurrence of the tuberculous infection.
  
  
  CONCLUSIONS
  The authors think that the single-stage anterior autogenous bone grafting and instrumentation are a safe and effective method in the surgical management of spinal tuberculosis.
authors.affiliation: Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai, China. lydai@etang.com
authors.forename: Li-Yang
authors.initials: LY
authors.lastname: Dai
authors.forename: Lei-Sheng
authors.initials: LS
authors.lastname: Jiang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Yi-Min
authors.initials: YM
authors.lastname: Cui
mesh_terms: D000328:Adult; D000368:Aged; D016025:Bone Transplantation; D003646:Debridement; D005260:Female; D006801:Humans; D016268:Internal Fixators; D007738:Kyphosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013123:Spinal Fusion / Q000009:adverse effects / Q000379:methods*; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology; D014399:Tuberculosis, Spinal / Q000150:complications / Q000175:diagnosis / Q000601:surgery*