title: An automated liquid handling system for polymerase chain reaction sample preparation.
abstract: An automated liquid handling system for dispensing liquid samples of sub-microliter volume has been developed. The system has eight nozzles composed of glass capillaries connected to syringe-style pumps. The distance between the nozzles can be changed from 4.5 to 9 mm, which corresponds to the distance between the wells in 96- and 384-well microplates, respectively. The eight nozzles of the system can aspirate and dispense liquid samples in both 96- and 384-well microplates. Sub-microliter volumes of reagents and samples were transferred between 96- and 384-well microplates using the system. This system was successfully used for PCR sample preparation.
authors.affiliation: Central Research Laboratory, Hitachi, Ltd., 1-280 Higashi-Koigakubo, Kokubunji, Tokyo 185-8601, Japan. uematsu@crl.hitachi.co.jp
authors.forename: Chihiro
authors.initials: C
authors.lastname: Uematsu
authors.forename: Ikuko
authors.initials: I
authors.lastname: Makino
authors.forename: Takahito
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Kunio
authors.initials: K
authors.lastname: Harada