title: [Current concepts in the management of pyogenic brain abscesses].
abstract: Brain abscesses are severe infections with lethal outcome in the case of delay in diagnosis and treatment. The authors report their experience about 30 patients with pyogenic brain abscesses treated between 1989 and 2000. The goal of the study is to analyse epidemiological, clinical and therapeutic aspects of this disease. The sex ratio (M:W) was 2,3 and the mean age was 34 years. Predisposing factors were sepsis of adjacent organs (53%) and bacteremia (30%). The clinical manifestations were: fever (83%), headaches (90%) and focal neurologic signs (57%). CT-scan findings were single lesions in 80% of cases. CT-scan showed a deep ring-enhancing lesion with surrounding edema in 77% of cases. Bacteriological agents in 13 cases (43%) were: 4 Staphylococcus aureus, 2 Neisseria meningitidis and 7 negative Gram bacilli. Medical treatment alone was in 77% of cases; seven patients benefited from medical and neurosurgical approaches. Death occured in 10% of cases.
authors.affiliation: Service des maladies infectieuses, Hôpital la Rabta, Tunis, Tunisie.
authors.forename: Kilani
authors.initials: K
authors.lastname: Badreddine
authors.forename: Ammari
authors.initials: A
authors.lastname: Lamia
authors.forename: Mnif
authors.initials: M
authors.lastname: Emna
authors.forename: Tiouiri
authors.initials: T
authors.lastname: Hanene
authors.forename: Kanoun
authors.initials: K
authors.lastname: Fakher
authors.forename: Goubontini
authors.initials: G
authors.lastname: Ahmed
authors.forename: Marrakchi
authors.initials: M
authors.lastname: Chahib
authors.forename: Zouiten
authors.initials: Z
authors.lastname: Faycel
authors.forename: Ben Chaabène
authors.initials: BC
authors.lastname: Taoufik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy; D001922:Brain Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents