Comparison and relation of indirect and direct dynamic indexes of cardiac pumping capacity in chronic heart failure.
Cardiac power output (CPO), the product of cardiac output (CO) and mean arterial pressure (MAP), is a direct measure of cardiac pumping capability and is strongly indicative of prognosis and exercise ability in patients with chronic heart failure (CHF). However, it is not as easily measured as indirect indicators of cardiac function, such as peak oxygen consumption (VO(2)) or peak "circulatory power" (CircP), the product of VO(2) and MAP. The relation between direct and indirect indexes of cardiac pumping capacity was evaluated in 219 ambulatory patients with CHF. CircP was found to have a direct and consistent relation with CPO, overall (R = 0.93, p <0.0001) and at peak exercise (R = 0.84, p < 0.0001). The results suggest CircP to be an adequate measure of cardiac pumping capacity when the more directly measured CPO is not available.
Williams
Simon G
SG
Cardiac Transplant Unit, Wythenshawe Hospital, Wythenshawe, Manchester, UK. simongwilliams@hotmail.com
Tzeng
Bing-H
BH
Barker
Diane
D
Tan
Lip-Bun
LB
D002302:Cardiac Output; D002908:Chronic Disease; D015444:Exercise; D005260:Female; D006333:Heart Failure / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption