title: Comment: extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Spinler
authors.forename: William
authors.initials: W
authors.lastname: Dager
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001120:Arginine / Q000031:analogs & derivatives; D006801:Humans; D019934:International Normalized Ratio / Q000379:methods; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D007677:Kidney Function Tests / Q000379:methods; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D010314:Partial Thromboplastin Time; D010875:Pipecolic Acids / Q000009:adverse effects / Q000627:therapeutic use*; D013449:Sulfonamides; D020246:Venous Thrombosis / Q000175:diagnosis / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D010875:Pipecolic Acids; D013449:Sulfonamides; D014859:Warfarin; D001120:Arginine; C031942:argatroban