title: [Comparison of Rhesus boxes in Hans and Uighurs].
abstract: OBJECTIVE
  To study the difference and similarity between Hans and Uighurs in regard to Rhesus box and its significance.
  
  
  METHODS
  The sequence specific primers of upstream, downstream and hybrid Rhesus boxes were designed on the basis of RHD gene sequence. The upstream, downstream and hybrid Rhesus boxes were determined by polymerase chain reaction-sequence specific primer(PCP-SSP) and mismatched PCR.
  
  
  RESULTS
  The percentage of RHD-/RHD-, RHD+/RHD- and RHD+/RHD+ genotypes ascertained in the unrelated Hans with RhD(-) were 61.40%, 34.21% and 4.39% respectively, while those in the unrelated Chinese Uighurs with RhD(-) were 94.44%, 2.78% and 2.78% respectively. Furthermore, all 6 cases of some other minorities were RHD-/RHD- types. The percentage of RHD-/RHD- and RHD+/RHD- genotypes ascertained in the unrelated Chinese Uighurs were significantly higher than those in Chinese Hans (P < 0.01), whereas no statistically significant difference in the percentage of RHD+/RDH+ genotype between the two groups was observed (P > 0.05).
  
  
  CONCLUSIONS
  The Rh blood group of Uighurs in Xingjiang possesses both Oriental and Caucasian characteristics, which embodies a special ethnical aspect of the Chinese nation and is in accord with the anthropologic research results.
authors.affiliation: Nanfang Hospital, First Military Medical University, Guangzhou, Guangdong, PR China.
authors.forename: Jiong-cai
authors.initials: JC
authors.lastname: Lan
authors.forename: Hua-you
authors.initials: HY
authors.lastname: Zhou
authors.forename: Xu-hua
authors.initials: XH
authors.lastname: Bai
authors.forename: Gui-zhi
authors.initials: GZ
authors.lastname: Pang
authors.forename: Xiao-zhu
authors.initials: XZ
authors.lastname: Wang
authors.forename: Ling-jun
authors.initials: LJ
authors.lastname: Cai
authors.forename: Qiong
authors.initials: Q
authors.lastname: Cao
authors.forename: Yin-ze
authors.initials: YZ
authors.lastname: Zhang
authors.forename: Rong
authors.initials: R
authors.lastname: Xia
authors.forename: Quan-ke
authors.initials: QK
authors.lastname: Yang
mesh_terms: D002681:China; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
chemical_list: D012204:Rh-Hr Blood-Group System