title: Mechanic stimulation of the soles support zones as a countermeasure of the contractile properties decline under microgravity conditions.
abstract: Decrease in muscle contractility is an inevitable consequence of exposure in microgravity. A wealth of currently accumulated facts is indicative of profound modifications in structure and function of the skeletal muscles in the absence of gravity. Investigations with humans during space flights of varying duration (L.I. Kakurin et al., 1971; I.B. Kozlovskaya et al., 1984, 1987, 1991;.), ground-based simulation studies (A.M. Genin et al., 1969; L.S. Grigorieva et al., 1983), and numerous experiments with animals (E.I. IIyina-Kakueva et al., 1979; O.M. Edgerton et al 1991; B.S. Shenkman et al., 1994) made it evident that removal of gravitational loading is fraught with significant reductions in the contractile properties of muscular fibers, especially noticeable in muscles-extensors. Results of ground-based simulation studies led to the hypothesis that changes in muscle contractility developing already after few days in microgravity conditions are consequent to reduction in support afferentation that plays an important role in initiation and maintenance of the activity of tonic motor units (A.V. Kirenskaya et al., 1986). In view of the above, an idea has been proposed to prevent losses in tonic muscles contractility by application of artificial support. Testing of this hypothesis was the theme of the present investigation.
authors.affiliation: Russian Federation State Research Center-Institute for Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia. dilia@newmail.ru
authors.forename: D
authors.initials: D
authors.lastname: Khusnutdinova
authors.forename: A
authors.initials: A
authors.lastname: Netreba
authors.forename: I
authors.initials: I
authors.lastname: Kozlovskaya
mesh_terms: D000328:Adult; D000843:Ankle Joint / Q000502:physiology; D005528:Foot; D006801:Humans; D007101:Immersion; D007537:Isometric Contraction; D008297:Male; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D011312:Pressure; D019415:Torque; D016138:Walking; D018544:Weightlessness Countermeasures; D018474:Weightlessness Simulation