Pregnancy and sickle cell disease.
With advances in management, men and women with sickle cell disease are enjoying an improved quality of life well into adulthood, when they may elect to plan a family. Pregnancy has been associated with exacerbation of sickle cell disease and may place women, especially those with sickle cell anemia (HbSS), at an additional risk for obstetric complications. Appropriate management by health care providers familiar with sickle cell diseases and high-risk obstetric care can result in a successful pregnancy for most women with sickle cell disease.
Hassell
Kathryn
K
Colorado Sickle Cell Treatment and Research Center, University of Colorado Health Sciences Center, Denver, CO 80262, USA. kathryn.hassell@uchsc.edu
D000755:Anemia, Sickle Cell / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000209:etiology / Q000628:therapy; D012306:Risk