Pharmacological correction of hemostasis-regulating function of the lungs in rats with uncomplicated pregnancy and experimental gestosis.
Fetal growth retardation, hypercoagulation, and changes in pulmonary fibrinolytic activity were observed during experimental gestosis induced by long-term feeding of a high-sodium diet. The course of fraxiparine treatment to correct gestosis improved hemostasis-regulating lung function, decreased coagulation activity of the arterial blood, and increased the weights of the placenta and fetus.
Myasnikova
V V
VV
Krasnodar Branch, Southern Department of the Russian Academy of Medical Sciences, Russia.
Galenko-Yaroshevskii
P A
PA
Lysenkov
S P
SP
Gigineishvili
M A
MA
Berberashvili
T M
TM
D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology*; D001724:Birth Weight / Q000187:drug effects; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000628:therapy; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D005333:Fetus / Q000187:drug effects; D005340:Fibrinogen / Q000032:analysis / Q000187:drug effects; D006487:Hemostasis / Q000187:drug effects*; D008168:Lung / Q000503:physiopathology*; D017762:Nadroparin / Q000494:pharmacology*; D010920:Placenta / Q000187:drug effects; D011225:Pre-Eclampsia / Q000097:blood* / Q000209:etiology / Q000628:therapy; D011247:Pregnancy; D011897:Random Allocation; D051381:Rats
D000925:Anticoagulants; D017762:Nadroparin; D005340:Fibrinogen