Recurrent infections caused by cefotaxime- and ciprofloxacin-resistant Salmonella enterica serotype choleraesuis treated successfully with imipenem.
We present a case of recurrent infection (infective spondilitis, psoas abscess, and bacteraemia) caused by a single strain of cefotaxime- and ciprofloxacin-resistant and bla(CMY-2)-containing Salmonella enterica serotype choleraesuis during a 4-month period in a patient with uremia. The patient was successfully treated with imipenem for 7 weeks. Our observation indicates that a carbapenem might be considered as a drug of choice for the treatment of infections caused by this emerging multi-resistant pathogen.
Jean
Shio-Shin
SS
Department of Critical Care Medicine and Internal Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan, ROC.
Lee
Yu-Tsang
YT
Guo
Su-Mei
SM
Hsueh
Po-Ren
PR
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D002439:Cefotaxime / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008875:Middle Aged; D016659:Psoas Abscess / Q000188:drug therapy / Q000382:microbiology; D012008:Recurrence; D012480:Salmonella Infections / Q000188:drug therapy / Q000382:microbiology; D019779:Salmonella enterica / Q000145:classification / Q000187:drug effects*; D013166:Spondylitis / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome; D014511:Uremia / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D015378:Imipenem; D002439:Cefotaxime