title: Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked.
authors.affiliation: Department of Biochemistry, University of Cambridge, UK.
authors.forename: Apoorva
authors.initials: A
authors.lastname: Bhatt
authors.forename: Christian B W
authors.initials: CB
authors.lastname: Stark
authors.forename: Barbara M
authors.initials: BM
authors.lastname: Harvey
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Gallimore
authors.forename: Yuliya A
authors.initials: YA
authors.lastname: Demydchuk
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: Spencer
authors.forename: James
authors.initials: J
authors.lastname: Staunton
authors.forename: Peter F
authors.initials: PF
authors.lastname: Leadlay
mesh_terms: D003500:Cyclization; D008968:Molecular Conformation; D008985:Monensin / Q000031:analogs & derivatives / Q000096:biosynthesis* / Q000737:chemistry*; D010084:Oxidation-Reduction; D011090:Polyenes / Q000737:chemistry*; D048630:Polyketide Synthases / Q000737:chemistry*; D013237:Stereoisomerism; D013302:Streptomyces / Q000201:enzymology / Q000235:genetics
chemical_list: D011090:Polyenes; D048630:Polyketide Synthases; D008985:Monensin