title: Predictors of outcome after sirolimus-eluting stent implantation for complex in-stent restenosis.
abstract: Few data are available on the effectiveness of sirolimus-eluting stent implantation for the treatment of in-stent restenosis, and no data exist about the predictors of outcome after sirolimus-eluting stent implantation for complex in-stent restenosis (diffuse, proliferative, or total occlusion). From April 2002 to May 2004, 136 patients with 161 complex in-stent restenoses underwent sirolimus-eluting stent implantation. At 9 months, 5 patients had died (3 of cardiac and 2 of noncardiac causes), no reinfarctions had occurred, and 11 target vessel revascularization procedures had been performed. The target vessel revascularization rate was 8%, and the in-segment binary restenosis rate was 17%. The predictors of the risk of recurrence were unstable angina as the clinical presentation of in-stent restenosis, an ostial location of the target lesion, lesion length, and sirolimus-eluting stent diameter < or =2.5 mm.
authors.affiliation: Division of Cardiology, Careggi Hospital, Florence, Italy.
authors.forename: Angela
authors.initials: A
authors.lastname: Migliorini
authors.forename: Merita
authors.initials: M
authors.lastname: Shehu
authors.forename: Nazario
authors.initials: N
authors.lastname: Carrabba
authors.forename: Letizia
authors.initials: L
authors.lastname: Giurlani
authors.forename: Renato
authors.initials: R
authors.lastname: Valenti
authors.forename: Piergiovanni
authors.initials: P
authors.lastname: Buonamici
authors.forename: Emilio V
authors.initials: EV
authors.lastname: Dovellini
authors.forename: Guido
authors.initials: G
authors.lastname: Parodi
authors.forename: David
authors.initials: D
authors.lastname: Antoniucci
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000628:therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009026:Mortality; D011237:Predictive Value of Tests; D011446:Prospective Studies; D020123:Sirolimus / Q000627:therapeutic use*; D015607:Stents; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus