Dealing with allelic dropout when reporting the evidential value in DNA relatedness analysis.
A method is suggested that allows the use of loci that have shown allelic dropout in kinship analysis as used for disaster victim identification (DVI) and missing person work (MP). This approach uses an extension of a previously published approach to modelling allelic dropout. This method may salvage some information in cases where allelic dropout is hindering DVI or MP work particularly in reconciliations involving a large number of bodies and pedigrees. It should not replace the pursuit of more complete DNA profiles by the normal rework process for such samples.
Buckleton
John
J
ESR, PB 92021, Auckland, New Zealand. John.Buckleton@esr.cri.nz
Triggs
Chris
C
D000483:Alleles; D016172:DNA Fingerprinting; D006801:Humans; D016013:Likelihood Functions; D008957:Models, Genetic