title: Antibiotic-laden cement: technique for uniform manual mixing.
abstract: The use of polymethyl methacrylate has revolutionized surgical technique in total joint arthroplasty. In addition, in an effort to reduce the rate of infections as well as to treat active infections, the practice of adding powdered antibiotics to the cement has become commonplace. A simple and efficient technique of mixing antibiotic powder into cement that creates a uniform distribution of antibiotic is introduced. In addition, this process reduces the presence of "antibiotic voids," which, if present can alter the physical properties of the cement itself.
authors.affiliation: Kaleida Health, Buffalo General Hospital, State University of New York at Buffalo, 14203, USA.
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Krackow
authors.forename: Michael A
authors.initials: MA
authors.lastname: Rauh
authors.forename: Randall M
authors.initials: RM
authors.lastname: Meredith
authors.forename: Sandeep
authors.initials: S
authors.lastname: Munjal
mesh_terms: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D004339:Drug Compounding / Q000379:methods; D007595:Joint Prosthesis / Q000009:adverse effects; D019904:Polymethyl Methacrylate; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D019904:Polymethyl Methacrylate