title: [Q fever in acute exacerbation of chronic lower respiratory tract infection].
abstract: We studied the effect of Q fever in acute exacerbation of chronic lower respiratory tract infection. The subjects consisted of 80 cases with acute exacerbation of chronic lower respiratory tract infection treated during the period from March 2002 till October 2004. Q fever was diagnosed using a PanBio Coxiella burnetii ELISA test kit. Two cases (2.5%) were positive for IgM in the acute stage, and were diagnosed as having acute infection by C. burnetii. They were elderly women with bronchiectasis, aged 76 and 82. They had no history of keeping cats or dogs, but the onset of acute exacerbation of chronic lower respiratory tract infection was June and March which is the breeding seasons for cats and dogs. Acute exacerbation of chronic lower respiratory tract infection were considerd to be a mixed infection with Pseudomonas aeruginosa (the 76-year-case) and Haemophilus influenzae (the 82-year-case). It is concluded that C. burnetii can induce exacerbation of chronic lower respiratory tract infection, their cases were considerd to be mixed infection with C. burnetii and other bacteria.
authors.affiliation: Center of Respiratory Diseases, Kawasaki Medical School Kawasaki Hospital.
authors.forename: Niro
authors.initials: N
authors.lastname: Okimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Kibayashi
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Mimura
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamato
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Kurihara
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Honda
authors.forename: Kohichi
authors.initials: K
authors.lastname: Osaki
authors.forename: Naoko
authors.initials: N
authors.lastname: Asaoka
authors.forename: Hideo
authors.initials: H
authors.lastname: Ohba
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016997:Coxiella burnetii / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D011778:Q Fever / Q000175:diagnosis / Q000209:etiology*; D012141:Respiratory Tract Infections / Q000150:complications* / Q000473:pathology
chemical_list: D007075:Immunoglobulin M