Serum creatine kinase levels and the number of sarcolemmal dystrophin disruptions in human skeletal muscle fibers under conditions of 7-day "dry" immersion.
9 male volunteers took part in the experiment. They were divided in two groups. 5 volunteers (control group) have been in "dry" immersion for 7 days. 4 volunteers (stimulated group) in addition to "dry" immersion were treated with artificial support stimulation. We investigated the number of muscle fibers with the disruptions of sarcolemmal dystrophin and serum creatine kinase levels. 7-day "dry" immersion does not change the mean number of muscle fibers with dystrophin disruptions, it leads to significant decrease of serum creatine kinase levels and does not influence on the sensitivity of sarcolemma to injury. Artificial support stimulation does not influence on these parameters.
Gasnikova
N M
NM
RF SRC-Institute of Biomedical Problems of Russian Academy of Sciences, Moscow, Russia. gasnikova@imbp.ru
Markin
A A
AA
Kozlovskaya
I B
IB
Larina
I M
IM
Shenkman
B S
BS
D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism*; D016189:Dystrophin / Q000378:metabolism*; D006801:Humans; D007101:Immersion; D008297:Male; D018485:Muscle Fibers, Skeletal / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism; D011312:Pressure; D012508:Sarcolemma / Q000201:enzymology / Q000378:metabolism; D018474:Weightlessness Simulation
D016189:Dystrophin; D003402:Creatine Kinase