title: Small intestinal submucosa intracardiac patch: an experimental study.
abstract: In this experimental study, small intestinal submucosa was implanted as an atrial prosthesis in calves. Echocardiography and histology showed this to be an impermeable prosthesis that develops a neointimal nonthrombogenic surface making it safe for repair of defects in a low-pressure system. Further study with small intestinal submucosa in an intracardiac position is warranted.
authors.affiliation: Cleveland Clinic Foundation Department of General Surgery, Cleveland, OH 44195, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Rosen
authors.forename: Eric E
authors.initials: EE
authors.lastname: Roselli
authors.forename: Cristiano
authors.initials: C
authors.lastname: Faber
authors.forename: Norman B
authors.initials: NB
authors.lastname: Ratliff
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Ponsky
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Smedira
mesh_terms: D000818:Animals; D001707:Biopsy, Needle; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002417:Cattle; D004195:Disease Models, Animal; D006084:Graft Rejection; D006085:Graft Survival; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000637:transplantation*; D007421:Intestine, Small; D008297:Male; D008943:Mitral Valve / Q000473:pathology* / Q000601:surgery*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D013524:Surgical Flaps