Acute choroidal closure caused by hemodialysis accident in an amyloidosic patient.
BACKGROUND
We report the case of a 43-year-old man haemodialysed for 20 years for systemic amyloidosis who underwent an acute choroidal occlusion after a haemodialysis accident.


METHODS
The patient had cardiac, pulmonary, neurovegetative and renal localizations of amyloidosis. He complained during a haemodialysis session of discomfort with abdominal pain, headache, bradycardia, vomiting, confusion and blurred vision. Acute haemolytic anemia was confirmed. In the following days, eyes were red and the vision was still altered.


RESULTS
Examination showed decreased visual acuity (VA) to 20/80 OU, low intraocular pressure (IOP), major vitritis and pigmentary alterations of the fundus with yellow retinal deposits. Fluorescein and indocyanine green angiographies showed amyloid retinal deposits, pigmentary alterations, normal retinal perfusion and massive choroidal hypoperfusion persisting in the late sequence. Steroid therapy was tried unsuccessfully. The situation slowly improved within 3 months with complete clearing of the vitreous opacities and stabilisation of the pigmentary alterations. VA progressively recovered to 20/30, 1 year after the onset of the disease, but IOP remained low and choroidal perfusion did not improve 2 years after the accident.


CONCLUSIONS
Choroidal complications of amyloidosis have never been described so far. The acute occlusion observed here was the consequence of an intravascular haemolytic event that completed the preexisting amyloid vascular infiltration.
Lemaitre-Labilloy
Claire
C
Department of Ophthalmology, Pitie-Salpetriere Hospital, 43-87 boulevard de l'Hôpital, 75013 Paris, France.
Bodaghi
Bahram
B
Cassoux
Nathalie
N
Lehoang
Phuc
P
D000208:Acute Disease; D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000628:therapy; D000743:Anemia, Hemolytic / Q000209:etiology*; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000209:etiology*; D002829:Choroid / Q000098:blood supply*; D019842:Ciliary Arteries / Q000473:pathology*; D004396:Coloring Agents; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D007429:Intraocular Pressure; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects*; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity
D004396:Coloring Agents; D007208:Indocyanine Green