title: Bax and Bcl-XL apoptosis protein mRNA in rat brain stem and cortex during ontogeny.
abstract: Bax mRNA level in fetal rat brain stem increases by day 40 of life and then decreases, while level of Bcl-XL mRNA reaches the adult value over one month. Bax mRNA level in the cerebral cortex decreases from day 8 to day 90 of life, while Bcl-XL mRNA level does not change. Judging from Bcl-XL/Bax mRNA ratio, cortical cells exhibit higher readiness to apoptosis than brain stem cells.
authors.affiliation: Laboratory of Genetic Base of Neuroendocrine Regulation, Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk, Moscow. anitik@bionet.nsc.ru
authors.forename: A V
authors.initials: AV
authors.lastname: Bannova
authors.forename: P N
authors.initials: PN
authors.lastname: Men'shanov
authors.forename: F A
authors.initials: FA
authors.lastname: Il'inykh
authors.forename: T S
authors.initials: TS
authors.lastname: Kalinina
authors.forename: N N
authors.initials: NN
authors.lastname: Dygalo
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D001933:Brain Stem / Q000378:metabolism*; D002540:Cerebral Cortex / Q000378:metabolism*; D005333:Fetus; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D051028:bcl-2-Associated X Protein / Q000235:genetics*; D051020:bcl-X Protein / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D051028:bcl-2-Associated X Protein; D051020:bcl-X Protein