title: [Determinants of postprandial lipemia measured as diurnal triglyceride profile in non diabetic normolipidemic subjects].
abstract: OBJECTIVE
  We decided to evaluate the clinical and biochemical predictors of postprandial lipemia, measured as daylong capillarly triglycerides (TGc) profiles, in normolipidemic non diabetic subjects.
  
  
  METHODS
  We studied 76 normolipidemic non diabetic subjects (45 premenopausal females). Accutrend was used to measure daylong TGc profiles during 3 days in 6 previously standardized points: fasting, pre and 3 h after dinner and lunch and at bedtime. The area under the curve of TGc (AUC-TGc) was determined as expression of postprandial lipemia.
  
  
  RESULTS
  Males showed significantly higher AUC-TGc (26.20 [11.00] vs 19.12 [6.57] in females; p < 0.001). Obese showed significantly higher values of AUC-TGc (27.87 [12.47] vs 20.05 [7.04]; p < 0.01). The AUC-TGc correlated with: age (r = 0.242; p < 0.05), body mass index (r = 0.312; p < 0.01), waist circumference (r = 0.394; p < 0.01), fasting plasma triglyceride (r = 0.634; p < 0.001), fasting insulinemia (r = 0.485; p < 0.001) and fasting HOMA (r = 0.484; p < 0.001). The multivariate analysis showed that HOMA (regression coefficient: 0.352; p = 0.02) and waist circumference (regression coefficient: 0.4; p = 0.05) were independent predictors of the AUC-TGc.
  
  
  CONCLUSIONS
  Independent determinants of postprandial lipemia were waist circumference and HOMA.
authors.affiliation: Hospital Clínico Universitario de Valencia, Departamento de Medicina, Universidad de Valencia, Valencia, Spain.
authors.forename: Cintia
authors.initials: C
authors.lastname: González
authors.forename: José T
authors.initials: JT
authors.lastname: Real
authors.forename: Amadaro
authors.initials: A
authors.lastname: Bartual
authors.forename: Felipe J
authors.initials: FJ
authors.lastname: Chaves
authors.forename: Ana B
authors.initials: AB
authors.lastname: García-García
authors.forename: Sebastián
authors.initials: S
authors.lastname: Blesa
authors.forename: Manuel
authors.initials: M
authors.lastname: Castro-Cabezas
authors.forename: Juan F
authors.initials: JF
authors.lastname: Ascaso
authors.forename: Rafael
authors.initials: R
authors.lastname: Carmena
mesh_terms: D000328:Adult; D019540:Area Under Curve; D001774:Blood Chemical Analysis; D015992:Body Mass Index; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood* / Q000378:metabolism; D007333:Insulin Resistance; D008297:Male; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood* / Q000378:metabolism; D049629:Waist-Hip Ratio
chemical_list: D014280:Triglycerides