title: Rational vaccine strategies against AIDS: background and rationale.
abstract: New vaccine candidates exploiting the rational combination of regulatory and structural HIV gene products are being developed within the program of the AIDS Vaccine Integrated Project (AVIP) and will be tested in comparative preclinical and clinical trials with the ultimate goal of selecting proper candidates for advanced clinical testing in developing countries.
authors.affiliation: AIDS National Center, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. ensoli@iss.it
authors.forename: Barbara
authors.initials: B
authors.lastname: Ensoli
mesh_terms: D016915:AIDS Vaccines / Q000235:genetics* / Q000276:immunology*; D002986:Clinical Trials as Topic; D004353:Drug Evaluation, Preclinical; D015658:HIV Infections / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans; D017778:Vaccines, Combined / Q000235:genetics / Q000276:immunology; D017361:Viral Nonstructural Proteins / Q000235:genetics / Q000276:immunology; D015678:Viral Structural Proteins / Q000235:genetics / Q000276:immunology
chemical_list: D016915:AIDS Vaccines; D017778:Vaccines, Combined; D017361:Viral Nonstructural Proteins; D015678:Viral Structural Proteins