title: Updates on acetaminophen toxicity.
abstract: APAP is likely to remain a common toxic exposure and continue to cause significant morbidity and mortality. To minimize the harm to patients, it is necessary for the clinician to be aware of the current diagnostic and therapeutic management of APAP poisoning. Despite the bulk of literature on APAP, management strategies are likely to continue to change as more studies are conducted to improve our understanding of nonacute ingestions and the role of prognostic markers in defining those most at risk for life-threatening hepatotoxicity.
authors.affiliation: Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia, Charlottesville, VA 22908, USA. ar6r@virginia.edu
authors.forename: Adam K
authors.initials: AK
authors.lastname: Rowden
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Norvell
authors.forename: David L
authors.initials: DL
authors.lastname: Eldridge
authors.forename: Mark A
authors.initials: MA
authors.lastname: Kirk
mesh_terms: D000082:Acetaminophen / Q000633:toxicity*; D018712:Analgesics, Non-Narcotic / Q000633:toxicity*; D004638:Emergency Treatment / Q000706:statistics & numerical data; D006801:Humans; D016031:Liver Transplantation; D011041:Poisoning / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D014481:United States / Q000453:epidemiology
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen