Atrial fibrillation: basic and clinical research at the Montreal Heart Institute.
The present article reviews pertinent contributions from the Montreal Heart Institute, Montreal, Quebec, to the understanding of the mechanisms and treatment of atrial fibrillation. The article discusses the usefulness of anticoagulant therapy, antiarrhythmic drug therapy for sinus rhythm maintenance, the electrophysiological basis of atrial fibrillation and the investigation of new energy sources for catheter ablation. Future directions at the Montreal Heart Institute are also briefly addressed.
Roy
Denis
D
Department of Medicine and Research Centre, Montreal Heart Institute, Faculty of Medicine, University of Montreal, Quebec. d-roy@icm-mhi.com
Talajic
Mario
M
Dubuc
Marc
M
Thibault
Bernard
B
Guerra
Peter G
PG
Macle
Laurent
L
Gagné
Pierre
P
Khairy
Paul
P
Nattel
Stanley
S
D000047:Academies and Institutes; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000503:physiopathology / Q000628:therapy; D035843:Biomedical Research / Q000639:trends; D002170:Canada; D006328:Cardiac Catheterization; D003452:Cryosurgery; D022062:Electrophysiologic Techniques, Cardiac; D004617:Embolism / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D006339:Heart Rate / Q000187:drug effects; D006801:Humans
D000889:Anti-Arrhythmia Agents; D000925:Anticoagulants