title: Results of silicone oil removal in patients with cytomegalovirus retinitis related retinal detachments.
abstract: OBJECTIVE
  To evaluate the percentage and risk indicators leading to retinal redetachment in HIV (human immunodeficiency virus) patients with CMV (cytomegalovirus) retinitis related retinal detachments that were repaired with silicone oil, and then subsequently underwent oil removal.
  
  
  METHODS
  Retrospective, noncomparative interventional case series.
  
  
  METHODS
  The study cohort consisted of a series of 15 eyes in 14 patients with HIV and CMV retinitis with a retinal detachment (RD) repaired with silicone oil at a single center and followed from the time of the CMV retinitis diagnosis through the time of silicone oil removal. Patient- and eye-specific data regarding demographic and clinical characteristics were collected retrospectively and statistical analyses were performed to compare differences between the eyes that had retinal detachments versus the eyes that remained attached following removal of silicone oil.
  
  
  RESULTS
  Eight eyes (53%) redetached after a median of 4.0 months following oil removal. Cataract surgery performed at the time of oil removal was a statistically significant risk factor for redetachment (P = .01). There was a trend for lower CD4 levels to be associated with a higher risk of retinal redetachment. The use of a scleral buckle at the time of surgery (initial RD repair or at the time of oil removal) did not reduce the risk of redetachment.
  
  
  CONCLUSIONS
  Approximately half of the eyes with CMV related retinal detachment may safely undergo oil removal. The risk factor for redetachment was simultaneous cataract extraction at the time of silicone oil removal. There was also a trend for lower CD4 levels to be associated with a higher risk of retinal redetachment.
authors.affiliation: Department of Ophthalmology, University of California San Diego La Jolla, California 92093, USA.
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Morrison
authors.forename: Laurie D
authors.initials: LD
authors.lastname: Labree
authors.forename: Stanley P
authors.initials: SP
authors.lastname: Azen
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Goldberg
authors.forename: William R
authors.initials: WR
authors.lastname: Freeman
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000601:surgery*; D000328:Adult; D018791:CD4 Lymphocyte Count; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000601:surgery*; D004322:Drainage; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors; D012591:Scleral Buckling; D012827:Silicone Oils; D016896:Treatment Outcome; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils