title: Thrombophilia and pregnancy.
abstract: Inherited and acquired thrombophilia are the main cause of thrombosis in pregnant women. A growing number of reports over the last 6 years suggest that these disorders are also associated with an increased incidence of vascular pathologies resulting in poor gestational outcome. This review discusses recent data on thrombophilia and vascular placental pathology, and then discusses therapies to prevent placental vascular thrombosis and to maximize successful gestational outcome.
authors.affiliation: Department of Hematology and Bone Marrow Transplantation, Rambam Medical Center, Haifa 31096, Isreal. b_Brenner@rambam.health.gov.il
authors.forename: Benjamin
authors.initials: B
authors.lastname: Brenner
mesh_terms: D000328:Adult; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D021041:Placental Circulation; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy / Q000209:etiology*; D011256:Pregnancy Outcome; D019851:Thrombophilia / Q000150:complications* / Q000188:drug therapy / Q000209:etiology
chemical_list: D005343:Fibrinolytic Agents