title: Migration modelling from food-contact plastics into foodstuffs as a new tool for consumer exposure estimation.
abstract: One important aspect within the European Union's public healthcare is the exposure of consumers to undesirable chemicals in the diet. Food-contact materials (FCM) are one potential contamination source and therefore of particular interest for food exposure assessment. On the other hand, scientific investigations concerning the migration potential and behaviour of food-packaging materials have demonstrated that diffusion in and migration from FCM are foreseeable physical and, in principle, mathematically describable processes. Because of this situation and the current state-of-the-art in migration science, a research project was initiated within the 5th Framework Programme of the European Commission. This project, with the acronym 'FOODMIGROSURE' (European Union Contract No. 'QLK1-CT2002-2390') started on 1 March 2003, was due to last 3 years and had the participation of nine European project partners (see the project website: www.foodmigrosure.org). The aim of the project was to extend currently existing migration models (which have been demonstrated to be applicable for less complex matrices such as food simulants) to foodstuffs themselves. In this way, the project aims to provide a novel and economic tool for estimation of consumer exposure to chemicals migrating from food-contact plastic materials under any actual contact conditions. In addition, the project aims to increase knowledge of the mechanisms of diffusion of organic compounds in foodstuffs and provide data on the partitioning effects between FCM and foods. Today the latter aspect is increasingly regarded as a fundamental influence parameter for migration into foods. Based on the project achievements, a much better scientific basis is available to allow scientifically appropriate amendments of European Union Directive 85/572/EEC as well as to support further developments with the so-called Plastics Directive 2002/72/EC. The paper introduces the project and presents an overview of the project work progress.
authors.affiliation: Fraunhofer Institut Verfahrenstechnik und Verpackung, Freising, Germany. roland.franz@ivv.fraunhofer.de
authors.forename: R
authors.initials: R
authors.lastname: Franz
mesh_terms: D001294:Attitude to Health; D001628:Beverages / Q000032:analysis / Q000633:toxicity; D002070:Butadienes / Q000032:analysis / Q000633:toxicity; D002273:Carcinogens / Q000032:analysis / Q000633:toxicity; D002611:Cheese / Q000032:analysis / Q000633:toxicity; D032084:Citrus sinensis; D003198:Computer Simulation; D053138:Cyclohexenes; D004032:Diet; D004781:Environmental Exposure / Q000009:adverse effects; D005504:Food Analysis; D005506:Food Contamination; D018857:Food Packaging; D006801:Humans; D007700:Kinetics; D000077222:Limonene; D008962:Models, Theoretical; D008970:Molecular Weight; D009281:Naphthalenes / Q000032:analysis / Q000633:toxicity; D010969:Plastics / Q000633:toxicity*; D011202:Poultry Products / Q000032:analysis / Q000633:toxicity; D012449:Safety; D020058:Styrene / Q000032:analysis / Q000633:toxicity; D013729:Terpenes / Q000032:analysis / Q000633:toxicity
chemical_list: D002070:Butadienes; D002273:Carcinogens; D053138:Cyclohexenes; D009281:Naphthalenes; D010969:Plastics; D013729:Terpenes; D020058:Styrene; D000077222:Limonene; C012939:1,4-diphenylbutadiene