title: A case of acute humoral rejection in liver transplantation: successful treatment with plasmapheresis and mycophenolate mofetil.
abstract: We present a case of a 23-year-old female who underwent orthotopic liver transplantation (OLTx) for biliary atresia, 22 years after a failed Kasai operation. Unusually, her postoperative course was complicated by severe acute humoral rejection. In this case report, we discuss her management as well as the role of plasmapheresis in treating allograft dysfunction secondary to acute humoral rejection in liver transplant patients.
authors.affiliation: Liver Unit, Freeman Hospital, Newcastle upon Tyne, UK. tonyrostron@doctors.org.uk
authors.forename: Anthony
authors.initials: A
authors.lastname: Rostron
authors.forename: Vaughan
authors.initials: V
authors.lastname: Carter
authors.forename: Mbithe
authors.initials: M
authors.lastname: Mutunga
authors.forename: Gary
authors.initials: G
authors.lastname: Cavanagh
authors.forename: Criostoir
authors.initials: C
authors.lastname: O'Suilleabhain
authors.forename: Alistair
authors.initials: A
authors.lastname: Burt
authors.forename: Bryon
authors.initials: B
authors.lastname: Jaques
authors.forename: David
authors.initials: D
authors.lastname: Talbot
authors.forename: Derek
authors.initials: D
authors.lastname: Manas
mesh_terms: D000208:Acute Disease; D000328:Adult; D000917:Antibody Formation; D001656:Biliary Atresia / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D016031:Liver Transplantation; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D010956:Plasmapheresis
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid