Exposure assessment for retrospective follow-up studies of semiconductor- and storage device-manufacturing workers.
OBJECTIVE
This exposure assessment was conducted in the first large study of mortality and cancer incidence in semiconductor and storage device manufacturing.


METHODS
Unique combinations of division, department and job codes and names (DDJ) from work history records were assigned to work groups and exposure categories. Agent exposure matrices assessed differences in potential exposures between groups. Changes in exposure over time were tracked by dividing the production history into manufacturing eras.


RESULTS
Nineteen work groups were developed to capture 310,351 unique DDJs from 1965-1999. Agent exposure matrices contrasted exposure potential to solvents, metals, and work in cleanrooms between groups, and three manufacturing eras were identified for each site.


CONCLUSIONS
The work groups, manufacturing eras and agent matrices have been used to classify workers in the study of cancer incidence and mortality.
Herrick
Robert F
RF
Department of Environmental Health, Harvard University School of Public Health, Boston, Massachusetts 02215, USA. Herrick@hohp.harvard.edu
Stewart
James H
JH
Blicharz
Drew
D
Beall
Colleen
C
Bender
Thomas
T
Cheng
Hong
H
Matthews
Robert
R
Sathiakumar
Nalini
N
Delzell
Elizabeth
E
D016248:Computer Storage Devices; D004812:Epidemiologic Methods; D005500:Follow-Up Studies; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology* / Q000401:mortality; D009784:Occupational Diseases / Q000453:epidemiology* / Q000401:mortality; D016273:Occupational Exposure; D009787:Occupational Medicine / Q000379:methods; D012666:Semiconductors