title: The therapeutic dilemma: how to use tadalafil.
abstract: Tadalafil, a type 5 phosphodiesterase inhibitor, is a new and effective therapy for erectile dysfunction. It has unique pharmacokinetic properties in its drug class, which also includes sildenafil and vardenafil. It is also well tolerated with few side-effects, and can be used in difficult patients such as neuropaths or diabetics.
authors.affiliation: Course of Endocrinology and Medical Sexology, Department of Experimental Medicine, University of L'Aquila 67100 L'Aquila, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Carosa
authors.forename: F
authors.initials: F
authors.lastname: Lombardo
authors.forename: P
authors.initials: P
authors.lastname: Martini
authors.forename: F
authors.initials: F
authors.lastname: Brandetti
authors.forename: E A
authors.initials: EA
authors.lastname: Jannini
mesh_terms: D002243:Carbolines / Q000009:adverse effects* / Q000145:classification / Q000493:pharmacokinetics / Q000627:therapeutic use*; D048909:Diabetes Complications; D004730:Endothelium, Vascular / Q000187:drug effects / Q000473:pathology; D007172:Erectile Dysfunction / Q000150:complications / Q000188:drug therapy*; D006207:Half-Life; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000150:complications; D010410:Penile Erection / Q000187:drug effects; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects / Q000145:classification / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000068581:Tadalafil; D014665:Vasodilator Agents / Q000009:adverse effects / Q000145:classification / Q000493:pharmacokinetics / Q000627:therapeutic use*
chemical_list: D002243:Carbolines; D010726:Phosphodiesterase Inhibitors; D014665:Vasodilator Agents; D000068581:Tadalafil