Orthotopic transplantation of fresh ovarian cortex: a report of two cases.
OBJECTIVE
To report two cases of orthotopic transplantation of fresh ovarian tissue.


METHODS
Academic hospital.


METHODS
Two patients with severe endometriosis, who underwent left oophorectomy for recurrent endometriosis.


METHODS
Ovarian cortex was reimplanted in the heterolateral orthotopic site.


RESULTS
Biopsies of the grafted tissue were taken 3 months after reimplantation. Viable primordial follicles were found. The presence of a neovascular capillary network was demonstrated.


CONCLUSIONS
Reimplantation of fresh ovarian cortex allows the survival of primordial follicles and may represent an alternative method for the preservation of ovarian cortex when oophorectomy is mandatory.
Donnez
Jacques
J
Department of Gynecology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium. donnez@gyne.ucl.ac.be
Squifflet
Jean
J
Dolmans
Marie-Madeleine
MM
Martinez-Madrid
Belen
B
Jadoul
Pascale
P
Van Langendonckt
Anne
A
D000328:Adult; D005260:Female; D006801:Humans; D010052:Ovariectomy / Q000379:methods*; D010053:Ovary / Q000601:surgery / Q000637:transplantation*; D016378:Tissue Transplantation; D014182:Transplantation, Autologous