title: Scrotal mass with fever and generalized lymphadenopathy in a young man secondary to Chlamydia trachomatis infection.
abstract: A young man presented with systemic upset and generalised lymphadenopathy. Later, it transpired that he was under investigation for a scrotal mass. Investigations were carried out to ascertain the cause of his symptoms including lymph node biopsy. Because of the presence of a scrotal mass in a sexually active male, a urinary Chlamydia ligase chain reaction (LCR) test was carried out. The result was positive and he was treated with doxycycline for 2 weeks. His symptoms settled and further, the urinary LCR was negative. We propose that Chlamydia trachomatis infection caused his illness and that urine PCR or LCR tests for Chlamydia is a convenient and useful investigation in sexually active males with generalised lymphadenopathy and fever of unknown origin.
authors.affiliation: Tropical and Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.
authors.forename: N E
authors.initials: NE
authors.lastname: Jenkins
authors.forename: L
authors.initials: L
authors.lastname: Radcliffe
authors.forename: Mike
authors.initials: M
authors.lastname: Beadsworth
authors.forename: H
authors.initials: H
authors.lastname: Mallinson
authors.forename: Fred
authors.initials: F
authors.lastname: Nye
authors.forename: Nick
authors.initials: N
authors.lastname: Beeching
mesh_terms: D000328:Adult; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D004604:Elephantiasis / Q000209:etiology* / Q000473:pathology; D005334:Fever / Q000209:etiology*; D005832:Genital Diseases, Male / Q000209:etiology / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D012611:Scrotum / Q000473:pathology*; D014556:Urine / Q000382:microbiology