title: Stereoselective synthesis of pyrrolidines from N-allyl oxazolidines via hydrozirconation-cyclization.
abstract: [reaction: see text] A new diastereoselective synthesis of pyrrolidines from readily available chiral N-allyl oxazolidines is presented. The construction of the pyrrolidine ring is achieved via a tandem hydrozirconation-stereoselective Lewis acid mediated cyclization sequence.
authors.affiliation: Réactions Sélectives et Applications, CNRS (UMR 6519) and Université de Reims, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Vasse
authors.forename: Antoine
authors.initials: A
authors.lastname: Joosten
authors.forename: Clément
authors.initials: C
authors.lastname: Denhez
authors.forename: Jan
authors.initials: J
authors.lastname: Szymoniak
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D015040:Zirconium / Q000737:chemistry*
chemical_list: D010080:Oxazoles; D011759:Pyrrolidines; C064210:oxazolidine; D015040:Zirconium