title: Living donor adult liver transplantation: a longitudinal study of the donor's quality of life.
abstract: We report the results of a prospective, longitudinal quality of life survey on our adult right lobe (RL) liver donors. A total of 47 donors were enrolled; a standard SF-36 form and 43 questions developed by our team were completed before donation, at 1 week, and 1, 3, 6 and 12 months after donation. There were no donor deaths. Twenty-nine complications occurred in 16 patients. Major complication rate was 12.8%. Employment status and personal finances were identified as major stressors. All donors who wished to return to work did so by 1 year (mean 3.4 months). Individuals reported between 0 dollars and 25,000 dollars in losses (wages, travel, lodging, etc.). Relationships with recipients and other family members were not altered significantly. Anticipated pain (predonation) was greater than actual pain reported. Donors indicated satisfaction with the donation process regardless of recipient outcome. Physical complaints were significant at 1 week and 1 month, but returned to baseline. Donor mental health remained stable. In conclusion, RL donors found the experience to be a positive one throughout the first postdonation year. The study identified areas (finances, employment and expected recipient outcomes) to be stressed as future donors are evaluated.
authors.affiliation: Department of Hepatobiliary Surgery and Liver Transplantation, Lahey Clinic, Burlington, MA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Verbesey
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Simpson
authors.forename: James J
authors.initials: JJ
authors.lastname: Pomposelli
authors.forename: Eric
authors.initials: E
authors.lastname: Richman
authors.forename: Alyson M
authors.initials: AM
authors.lastname: Bracken
authors.forename: Kathryn
authors.initials: K
authors.lastname: Garrigan
authors.forename: Hong
authors.initials: H
authors.lastname: Chang
authors.forename: Roger L
authors.initials: RL
authors.lastname: Jenkins
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Pomfret
mesh_terms: D000328:Adult; D003365:Costs and Cost Analysis; D003863:Depression / Q000453:epidemiology; D004522:Educational Status; D004651:Employment; D005190:Family; D005260:Female; D006498:Hepatectomy / Q000191:economics / Q000523:psychology*; D006801:Humans; D019520:Living Donors / Q000523:psychology*; D008137:Longitudinal Studies; D008297:Male; D010149:Postoperative Pain; D011183:Postoperative Complications / Q000453:epidemiology; D011788:Quality of Life; D011795:Surveys and Questionnaires; D020858:Tissue and Organ Harvesting / Q000191:economics / Q000523:psychology