title: Sesquiterpene lactones from Centaurea musimomum. Antiplasmodial and cytotoxic activities.
abstract: The chloroform extract of the aerial parts of Centaurea musimomum exhibited significant activity against Plasmodium falciparum. The phytochemical study of this extract gave seven native and four acetylated sesquiterpene lactones.
authors.affiliation: Département de Chimie, Faculté des Sciences, Université Mentouri de Constantine, Route de Aïn El Bey 25000, Constantine, Algérie.
authors.forename: Kamel
authors.initials: K
authors.lastname: Medjroubi
authors.forename: Fadila
authors.initials: F
authors.lastname: Benayache
authors.forename: Jaime
authors.initials: J
authors.lastname: Bermejo
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification / Q000494:pharmacology*; D000981:Antiprotozoal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D031179:Centaurea / Q000737:chemistry*; D007783:Lactones / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010963:Plasmodium falciparum / Q000187:drug effects; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000903:Antibiotics, Antineoplastic; D000981:Antiprotozoal Agents; D007783:Lactones; D010936:Plant Extracts; D012717:Sesquiterpenes