Effect of muscular contraction on magnetization transfer detected at 1.5 T.
The effect of rigor (formation of actomyosin complexes) on magnetization transfer was observed with a 1.5 T clinical magnetic resonance (MR) imaging system. The magnetization transfer ratio of chemically skinned (calcium-sensitive) muscle fiber preparations increased much more in a rigor state than in a relaxed state, while that of calcium-insensitive fiber preparations and solutions showed no difference. These results suggest that the formation of actomyosin complexes increased the magnetization transfer ratio. A clinical MR system is not only effective for medical imaging, but also has the potential to demonstrate physiological characteristics.
Hatakenaka
Masamitsu
M
Department of Radiology, Kyushu University Hospital at Beppu, 4546 Tsurnihara, Tsurumi, Beppu, Oita 874-0838, Japan. hatake@beppu.kyushu-u.ac.jp
D000205:Actomyosin / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D005260:Female; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000502:physiology; D011817:Rabbits
D000205:Actomyosin