Effects of artificial support stimulation on fiber and molecular characteristics of soleus muscle in men exposed to 7-day dry immersion.
Artificial support stimulation is known to attenuate or prevent many motor or skeletal muscle effects of actual or simulated microgravity. The present study was purposed to analyze the effects of artificial support on human soleus fibers after 7-day exposure to supportless environment. 8 healthy male volunteers were exposed to dry immersion in supine position for 7 days according to Shulzhenko and Vil-Villiams (1972). 4 of them worn the support device which provided them with plantar stimulation in regime described elsewhere.
Litvinova
K S
KS
SRC Institute for Biomedical Problems RAS, Laboratory of Myology, Moscow, Russia. litvinova@imbp.ru
Vikhlyantsev
I M
IM
Kozlovskaya
I B
IB
Podlubnaya
Z A
ZA
Shenkman
B S
BS
D064211:Connectin; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007101:Immersion; D008297:Male; D008565:Membrane Proteins / Q000378:metabolism; D009119:Muscle Contraction / Q000502:physiology; D018485:Muscle Fibers, Skeletal / Q000502:physiology*; D009124:Muscle Proteins / Q000378:metabolism; D018482:Muscle, Skeletal / Q000502:physiology*; D018995:Myosin Heavy Chains / Q000378:metabolism; D011312:Pressure; D011494:Protein Kinases / Q000378:metabolism; D016683:Supine Position; D018474:Weightlessness Simulation
D064211:Connectin; D008565:Membrane Proteins; D009124:Muscle Proteins; C577285:TTN protein, human; C035620:nebulin; D011494:Protein Kinases; D018995:Myosin Heavy Chains