Improvement of islet culture with sericin.
Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerated the proliferation of the rat insulinoma cell line RIN-5F and improved the serum-free culture of rat islets.
Ogawa
Akiko
A
Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1, Bunkyo, Fukui 910-8507, Japan.
Terada
Satoshi
S
Kanayama
Takanori
T
Miki
Masao
M
Morikawa
Mitsuhiro
M
Kimura
Toshihisa
T
Yamaguchi
Akio
A
Sasaki
Masahiro
M
Yamada
Hideyuki
H