Myalgia and cramps associated with zolmitriptan.
OBJECTIVE
To report a patient with myalgia and cramps possibly induced by the antimigrainous agent zolmitriptan.


METHODS
A 27-year-old woman with episodes of common migraine developed cramps and generalized myalgia after the use of intranasal zolmitriptan 5 mg to treat 3 episodes of migraine. This side effect had not occurred with oral zolmitriptan 2.5 mg.


CONCLUSIONS
Myalgia and cramps should be considered a possible dose-dependent adverse effect of zolmitriptan.
Alonso-Navarro
Hortensia
H
Servicio de Neurología, Hospital Universitario San Juan, Alicante, Spain.
Jiménez-Jiménez
Félix Javier
FJ
D000281:Administration, Intranasal; D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy; D009120:Muscle Cramp / Q000139:chemically induced*; D009135:Muscular Diseases / Q000139:chemically induced*; D023303:Oxazolidinones / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D010146:Pain / Q000139:chemically induced; D017366:Serotonin Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014363:Tryptamines / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use
D023303:Oxazolidinones; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C089750:zolmitriptan