title: Sclerosing perineurioma: Tumor of the hand with a short T2.
abstract: We present two cases of sclerosing perineurioma, a rare soft tissue tumor, in the palm and the ring finger respectively, presenting as a small, painless and subcutaneous mass. This tumor has a predilection for the digits and palms of young, predominantly male adults. In the present cases the tumors showed very low signal intensity on T2-weighted magnetic resonance (MR) images. Histologically they contained abundant collagen and hyalinized stroma, which would account for areas of low signal intensity on T2-weighted MR images. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen and human erythrocyte glucose transporter 1 and negative for S-100 protein. To the best of our knowledge, the appearance of sclerosing perineurioma on MR imaging has not been previously reported in the English-language literature. Sclerosing perineurioma should be considered in the differential diagnosis of hand tumors when the tumor shows low signal intensity on T2-weighted MR images.
authors.affiliation: Division of Diagnostic Radiology and Nuclear Medicine, National Cancer Center Hospital, 5-1-1, Tsukiji, 104-0045 Tokyo, Japan.
authors.forename: Mototaka
authors.initials: M
authors.lastname: Miyake
authors.forename: Ukihide
authors.initials: U
authors.lastname: Tateishi
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Maeda
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Arai
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Seki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Kazuro
authors.initials: K
authors.lastname: Sugimura
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005385:Fingers / Q000473:pathology* / Q000601:surgery; D006225:Hand / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012598:Sclerosis