Annular elastolytic giant cell granuloma in an infant: improvement after treatment with oral tranilast and topical pimecrolimus.
Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-old boy that was successfully treated with oral tranilast and topical pimecrolimus (Elidel 1.0% cream).
Lee
Hae-Woong
HW
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Lee
Mi-Woo
MW
Choi
Jee-Ho
JH
Moon
Kee-Chan
KC
Koh
Jai-Kyoung
JK
D000284:Administration, Oral; D000287:Administration, Topical; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004547:Elastic Tissue / Q000473:pathology*; D016460:Granuloma Annulare / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D062367:ortho-Aminobenzoates / Q000008:administration & dosage / Q000627:therapeutic use*
D018926:Anti-Allergic Agents; D007166:Immunosuppressive Agents; D062367:ortho-Aminobenzoates; C117268:pimecrolimus; C012293:tranilast; D016559:Tacrolimus