title: Subfascial endoscopic perforating vein surgery (SEPS) for the treatment of venous ulcers.
abstract: Lower extremity ulcerations that result from venous hypertension are a significant cause of disability in Western nations. Venous ulcers, highly related to lower extremity venous valvular incompetence and post-thrombotic syndrome, demonstrate a protracted course of healing with a high recurrence rate when managed conservatively. Effective treatment includes correcting the elevated lower extremity venous pressure using non-invasive (compression therapy) or invasive modalities (removal or correction of incompetent venous segments, most commonly the greater saphenous vein). Minimally invasive subfascial endoscopic perforating vein surgery, performed on an outpatient basis, allows ligation of incompetent Cockett perforating veins. Venous ulcer healing rates of 88% and infrequent wound complications have been reported using this technique. Using 5-mm cameras and trocars that are available for other endoscopic surgeries could further improve this technique; creating ports smaller than the traditional 15-mm incisions would subsequently reduce tissue disruption. In addition, the etiology of recurrent ulceration and the failure of the primary ulcer to heal are not completely understood. If these poor outcomes can be further defined, even higher rates of wound healing may be attained using this procedure. Significant efforts have been devoted to elucidating the exact mechanism of skin breakdown from venous hypertension but the pathophysiology of this process is still not understood.
authors.affiliation: University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Tae W
authors.initials: TW
authors.lastname: Chong
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Bott
authors.forename: John A
authors.initials: JA
authors.lastname: Kern
authors.forename: Benjamin B
authors.initials: BB
authors.lastname: Peeler
authors.forename: Curtis G
authors.initials: CG
authors.lastname: Tribble
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Harthun
mesh_terms: D004724:Endoscopy / Q000379:methods*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D014647:Varicose Ulcer / Q000503:physiopathology / Q000601:surgery*