title: Bacterial interference for prevention of urinary tract infection: a prospective, randomized, placebo-controlled, double-blind pilot trial.
abstract: This prospective, randomized, placebo-controlled, double-blind pilot trial examined the efficacy of bacterial interference in preventing urinary tract infection (UTI) in 27 patients with spinal cord injury. Patients whose bladders became colonized with Escherichia coli 83972 were half as likely (P=.01) than noncolonized patients to develop UTI during the subsequent year.
authors.affiliation: Michael E. Debakey Veterans Affairs Medical Center, Houston, Texas, USA. rdarouiche@aol.com
authors.forename: Rabih O
authors.initials: RO
authors.lastname: Darouiche
authors.forename: John I
authors.initials: JI
authors.lastname: Thornby
authors.forename: Colleen
authors.initials: C
authors.lastname: Cerra-Stewart
authors.forename: William H
authors.initials: WH
authors.lastname: Donovan
authors.forename: Richard A
authors.initials: RA
authors.lastname: Hull
mesh_terms: D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004926:Escherichia coli / Q000145:classification / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D013119:Spinal Cord Injuries / Q000150:complications; D001743:Urinary Bladder / Q000382:microbiology; D014546:Urinary Catheterization / Q000009:adverse effects; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control* / Q000652:urine; D014556:Urine / Q000382:microbiology