title: Hypodontia in an adolescent with the HbSC genotype: a case report.
abstract: The haemoglobin SC (HbSC) genotype is a variant form of haemoglobin disorder that often presents less frequent clinical symptoms of sickle cell disease (SCD) than the homozygous state (HbSS). Various dental abnormalities, such as enamel hypoplasia, hypomineralization, midline diastema and delayed eruption of the teeth, have been associated with SCD. This report presents the case of an adolescent patient with HbSC who had hypodontia, transposition of a permanent canine, retained primary teeth, multiple carious lesions and poor oral hygiene complicated by sickle cell crisis. This report focuses on the need for preventive care in such patients to reduce functional and aesthetic complications.
authors.affiliation: Department of Child Dental Health, College of Medicine, University of Lagos, Lagos, Nigeria. tored@nova.net.ng
authors.forename: F A
authors.initials: FA
authors.lastname: Oredugba
mesh_terms: D000293:Adolescent; D000848:Anodontia / Q000209:etiology*; D017742:Dental Care for Chronically Ill; D003731:Dental Caries / Q000150:complications; D005260:Female; D006450:Hemoglobin SC Disease / Q000150:complications*; D006801:Humans; D014079:Tooth Eruption, Ectopic / Q000209:etiology