title: Isoquinolone and protoberberine alkaloids from Stephania rotunda.
abstract: Chemical investigation of Stephania rotunda Lour. growing in Viet Nam led to the isolation and structural elucidation of three new alkaloids, 5-hydroxy-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one (1), thaicanine 4-O-beta-D-glucoside (6), as well as (-)-thaicanine N-oxide (4-hydroxycorynoxidine) (8), along with 23 known alkaloids. These structures were determined on the basis of MS and NMR spectroscopic data.
authors.affiliation: Institute of Chemistry, Vietnamese Academy of Science and Technology, Hanoi, Viet Nam.
authors.forename: T T
authors.initials: TT
authors.lastname: Thuy
authors.forename: A
authors.initials: A
authors.lastname: Porzel
authors.forename: K
authors.initials: K
authors.lastname: Franke
authors.forename: L
authors.initials: L
authors.lastname: Wessjohann
authors.forename: T V
authors.initials: TV
authors.lastname: Sung
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D001600:Berberine Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification; D007546:Isoquinolines / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009005:Monosaccharides / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization; D031607:Stephania / Q000737:chemistry*; D014744:Vietnam
chemical_list: C505636:5-hydroxy-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one; D000470:Alkaloids; D001600:Berberine Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; D007546:Isoquinolines; D009005:Monosaccharides; C505638:thaicanine 4-O-beta-D-glucoside; C505637:thaicanine N-oxide (4-hydroxycorynoxidine); C009090:protoberberine