The synthesis and directed ortho-lithiation of 4-tert-butylsulfinyl[2.2]paracyclophane.
The ortho-lithiation of one diastereoisomer of 4-tert-butylsulfinyl[2.2]paracyclophane is the key step to the synthesis of a range of 4,5-disubstituted [2.2]paracyclophane derivatives.
Hitchcock
Peter B
PB
Department of Chemistry, University of Sussex, Falmer, Brighton, UKBN1 9QJ.
Rowlands
Gareth J
GJ
Seacome
Richard J
RJ