Chronic outpatient sildenafil therapy for pulmonary hypertension in a child after cardiac surgery.
We report the case of a 14-month-old male with d-transposition of the great arteries, ventricular septal defect, and pulmonary hypertension successfully treated with long-term sildenafil following cardiac surgery. To our knowledge, this is the first published report of long-term sildenafil treatment in a child after corrective cardiac surgery.
Knoderer
C A
CA
Riley Hospital for Children, 702 Barnhill Drive, Room 1016, Indianapolis, IN 46202, USA. cknoderer@clarian.org
Ebenroth
E S
ES
Brown
J W
JW
D006348:Cardiac Surgical Procedures; D006345:Heart Septal Defects, Ventricular / Q000601:surgery; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D007223:Infant; D008134:Long-Term Care; D008297:Male; D010351:Patient Discharge; D010879:Piperazines / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014188:Transposition of Great Vessels / Q000601:surgery; D014665:Vasodilator Agents / Q000627:therapeutic use*
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate