[Plasma cell leukaemia].
We report a case of primary plasma cell leukaemia, with an absolute count of plasma cells of 53 Giga/L, diagnosed in a 83-year-old woman. The patient's condition improved, with no circulating plasma cells after 3 weeks of treatment, in response to the combination of thalidomide and dexamethasone administered for 5 days followed by thalidomide alone. The clinical presentation, the morphological, flow cytometric and pathophysiological characteristics of the plasma cell leukaemia and the treatment are summarised in this paper.
Rodriguez
C
C
Laboratoire d'hématologie, Groupe hospitalier Charles Foix Jean Rostand, Ivry Sur Seine.
Pont
J-C
JC
Gouin-Thibault
I
I
Andrieu
A-G
AG
Molina
T
T
Le Tourneau
A
A
Le Garff-Tavernier
M
M
Siguret
V
V
Chaibi
P
P
D000369:Aged, 80 and over; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000175:diagnosis* / Q000188:drug therapy; D013792:Thalidomide / Q000627:therapeutic use*
D020533:Angiogenesis Inhibitors; D000893:Anti-Inflammatory Agents; D013792:Thalidomide; D003907:Dexamethasone