Annual increase in body mass index in children with asthma on higher doses of inhaled steroids.
There is a greater annual increase in body mass index in children with asthma receiving inhaled steroids at a dose > or =400 microg/day (0.5 kg/m2/year; n=100) compared with those receiving < or =200 microg/day (0.1 kg/m2/year; n=98) (P=.0003). This is consistent with an annual increase in body fat in children with asthma receiving > or =400 microg/day of inhaled steroids.
Jani
Meghna
M
Division of Maternal and Child Health Sciences, University of Dundee Medical School, Ninewells Hospital and Medical School, Dundee, Scotland, UK.
Ogston
Simon
S
Mukhopadhyay
Somnath
S
D000280:Administration, Inhalation; D000730:Androstadienes / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001249:Asthma / Q000188:drug therapy*; D001507:Beclomethasone / Q000008:administration & dosage; D015992:Body Mass Index; D019819:Budesonide / Q000008:administration & dosage; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D000068298:Fluticasone; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male
D000730:Androstadienes; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D019819:Budesonide; D000068298:Fluticasone; D001507:Beclomethasone