title: Deamination of the amino acid fragment in imine metallacycles: unexpected synthesis of an NH-aldimine organometallic compound.
abstract: We report that the action of Lewis bases, such as triphenylphosphine, pyridine, or trimethylamine, on imine metallacycles derived from amino acids leads to the formation of the first organometallic compound of an NH aldimine, a highly reactive organic species, and the corresponding alpha-ketoester, in a deamination reaction that mimics the metabolism of alpha-amino acids. The synthesis of different cyclopalladated compounds by a reaction between palladium acetate and the Schiff bases 2,4,6-Me(3)C(6)H(2)CH=NCH(R(1))COOR(2) (R(1) = CH(2)Ph, R(2) = Et and R(1) = Ph, R(2) = Me) is also reported.
authors.affiliation: Departament de Química Inorgànica, Universitat de Barcelona, Spain.
authors.forename: Joan
authors.initials: J
authors.lastname: Albert
authors.forename: J Magali
authors.initials: JM
authors.lastname: Cadena
authors.forename: Asensio
authors.initials: A
authors.lastname: González
authors.forename: Jaume
authors.initials: J
authors.lastname: Granell
authors.forename: Xavier
authors.initials: X
authors.lastname: Solans
authors.forename: Mercè
authors.initials: M
authors.lastname: Font-Bardia
mesh_terms: D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D010649:Phenylalanine / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D010649:Phenylalanine; D010165:Palladium