title: [Contrast-media-induced nephrotoxicity].
abstract: The use of diagnostic and therapeutic catheterization is increasing and so is the exposure to radiocontrast media. As a consequence, an increasing incidence of contrast media-associated nephropathy is being observed. This article reviews pathogenesis, clinical symptoms and preventive measures of contrast media-associated nephropathy. Most important prophylactic measures is identification of high-risk patients, careful selection to be exposed to contrast media, application of non-ionic low osmolality or -- most recently -- iso-osmolality contrast media, adjusted hydration with isotonic saline before/during catheter interventions, and potentially the administration of acetylcysteine.
authors.affiliation: Universität Rostock, Klinik und Poliklinik für Innere Medizin, Abteilung für Kardiologie.
authors.forename: E
authors.initials: E
authors.lastname: Adolph
authors.forename: T
authors.initials: T
authors.lastname: Chatterjee
authors.forename: H
authors.initials: H
authors.lastname: Ince
authors.forename: H
authors.initials: H
authors.lastname: Eckard
authors.forename: T
authors.initials: T
authors.lastname: Rehders
authors.forename: S
authors.initials: S
authors.lastname: Kische
authors.forename: S
authors.initials: S
authors.lastname: Drawert
authors.forename: M
authors.initials: M
authors.lastname: Petzsch
authors.forename: C A
authors.initials: CA
authors.lastname: Nienaber
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D017700:Embolism, Cholesterol / Q000139:chemically induced; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D012307:Risk Factors
chemical_list: D003287:Contrast Media