title: Phenolic acids analysis in ligusticum chuanxiong using HPLC.
abstract: A reversed-phase high-performance liquid chromatographic method with diode array UV detection is developed for the determination of five kinds of phenolic acids common in herbal medicines. Based on this method, ferulic acid and caffeic acid are found to be two main phenolic acids in Chuanxiong (one of the important crude drugs in traditional Chinese medicine). More important, ferulic acid is found to exist in free form, and caffeic acid--a previously unreported component--is found to exist in esterified or insoluble-bound form.
authors.affiliation: Key Lab of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors.forename: Yan-Xia
authors.initials: YX
authors.lastname: Zhao
authors.forename: Ming-Yu
authors.initials: MY
authors.lastname: Ding
authors.forename: De-Lin
authors.initials: DL
authors.lastname: Liu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D062385:Hydroxybenzoates / Q000032:analysis*; D030004:Ligusticum; D013058:Mass Spectrometry; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004365:Drugs, Chinese Herbal; D062385:Hydroxybenzoates; C017616:phenolic acid; C101574:chuangxiong extract