Graves' ophthalmopathy: comparison of the Doppler sonography parameters with the clinical activity score.
OBJECTIVE
Our aim was to compare the Doppler ultrasonography (US) parameters with clinical activity score (CAS) in patients with Graves' ophthalmopathy.


METHODS
Blood flow parameters in the ophthalmic artery (OA), superior ophthalmic vein (SOV), central retinal artery (CRA) and central retinal vein (CRV) were measured by Doppler US in 118 patients with Graves' disease in 3 groups (A, B, and C) and 20 control subjects. Group A included 25 patients with CAS value "0"; group B 55 patients with CAS value "1 or 2"; group C 38 patients with CAS value "3 or above."


RESULTS
Peak systolic velocities (PSV) and end-diastolic velocities (EDV) in the OA, PSV, and in the CRA calculated for group C were significantly higher than for group A, group B, and the control group. Resistance index in the OA and maximal velocity (MV) in the SOV calculated for group C were significantly lower than those calculated for group A, group B, and the control group.


CONCLUSIONS
Doppler parameters of MV in SOV, PSV and EDV in OA, and PSV in CRA seem to be helpful in the differentiation of active and inactive phases of Graves' ophthalmopathy.
Yanik
Bahar
B
SSK Ankara Egitim Hastanesi (Social security Ankara Hospital), Department of Radiology, TR-06110, Dişkapi, Ankara, Turkey.
Conkbayir
Işik
I
Acaroglu
Golge
G
Hekimoglu
Baki
B
D000328:Adult; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D003971:Diastole / Q000502:physiology; D005123:Eye / Q000098:blood supply*; D005260:Female; D049970:Graves Ophthalmopathy / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000502:physiology; D011446:Prospective Studies; D012016:Reference Values; D012039:Regional Blood Flow; D012161:Retinal Artery / Q000502:physiology; D012169:Retinal Vein / Q000502:physiology; D012720:Severity of Illness Index; D013599:Systole / Q000502:physiology; D018615:Ultrasonography, Doppler, Color