Effect of praseodymium(III) on zinc(II) species in human interstitial fluid.
A multiphase model of metal ion species in human interstitial fluid was constructed under physiological conditions. The effect of Pr(III) on Zn(II) species was studied. At the normal conditions, Zn(II) species mainly distribute in [Zn(HSA)], [Zn(IgG)], and [Zn(Cys)(2)H](+). With the Pr(III) level increased, the apparent competition of Pr(III) for ligands lead to the redistribution of Zn(II) species.
Zhang
Haiyuan
H
Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, People's Republic of China.
Wang
Jinping
J
Lu
Xin
X
Yang
Kuiyue
K
Niu
Chunji
C
D001667:Binding, Competitive; D003198:Computer Simulation; D045604:Extracellular Fluid / Q000378:metabolism*; D008024:Ligands; D008954:Models, Biological; D011221:Praseodymium / Q000378:metabolism* / Q000494:pharmacology; D015032:Zinc / Q000378:metabolism*
D008024:Ligands; D015032:Zinc; D011221:Praseodymium