Bio-guided isolation of the cytotoxic corytenchine and isocoreximine from roots of Annona cherimolia.
The roots of Annona cherimolia have been shown to contain the known tetrahydroprotoberberine alkaloids corytenchine (1) and isocoreximine (2), investigated for their cytotoxic properties.
Martínez-Vázquez
Mariano
M
Instituto de Química, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, México, D.F. México.
De la Cueva Lozano
Diana G
DG
Estrada-Reyes
Rosa
R
González-Lugo
Nadia Margarita
NM
Ramírez Apan
Teresa
T
Heinze
Gerardo
G
D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology*; D031041:Annona / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D001600:Berberine Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D018517:Plant Roots / Q000737:chemistry
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; C507790:corytenchine; C507791:isocoreximine