title: In vitro photo-release of a TRPV1 agonist.
abstract: Intracellular photolysis of a novel 'caged' capsaicin analogue results in in vitro activation of the capsaicin receptor TRPV1.
authors.affiliation: EaStCHEM, School of Chemistry and Centre for Biomolecular Sciences, University of St. Andrews, St. Andrews, Fife KY16 9ST, UK.
authors.forename: James L
authors.initials: JL
authors.lastname: Carr
authors.forename: Kerrie N
authors.initials: KN
authors.lastname: Wease
authors.forename: Michael P
authors.initials: MP
authors.lastname: Van Ryssen
authors.forename: Suzanne
authors.initials: S
authors.lastname: Paterson
authors.forename: Ben
authors.initials: B
authors.lastname: Agate
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Gallagher
authors.forename: C Tom A
authors.initials: CT
authors.lastname: Brown
authors.forename: Roderick H
authors.initials: RH
authors.lastname: Scott
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Conway
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D002211:Capsaicin / Q000031:analogs & derivatives*; D002478:Cells, Cultured; D004224:Diterpenes / Q000494:pharmacology; D004594:Electrophysiology; D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D008027:Light; D008956:Models, Chemical; D009474:Neurons / Q000378:metabolism; D011485:Protein Binding; D051381:Rats; D013329:Structure-Activity Relationship; D050916:TRPV Cation Channels / Q000037:antagonists & inhibitors*
chemical_list: D004224:Diterpenes; D007473:Ion Channels; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; C493922:Trpv1 protein, rat; C024353:resiniferatoxin; D002211:Capsaicin; D002118:Calcium