Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
Kovalevskaya
Nadezhda V
NV
Center for Drug Chemistry, Moscow, 119815 , Russia.
Smurnyy
Yegor D
YD
Polshakov
Vladimir I
VI
Birdsall
Berry
B
Bradbury
Alan F
AF
Frenkiel
Tom
T
Feeney
James
J
D001665:Binding Sites; D003460:Crystallization; D018360:Crystallography, X-Ray; D005493:Folic Acid Antagonists / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D009249:NADP / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D011487:Protein Conformation; D013762:Tetrahydrofolate Dehydrogenase / Q000737:chemistry*; D014295:Trimethoprim / Q000737:chemistry*
D005493:Folic Acid Antagonists; D009249:NADP; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase