title: Efficacy of a combination of imidacloprid and moxidectin against parasites of reptiles and rodents: case reports.
abstract: A new compound containing imidacloprid 10% (w/v) and moxidectin 2.5% (w/v) (Advantage multi, Advocate) was applied as a spot-on treatment to mice experimentally infected with Trichuris muris. Case reports of reptiles found positive for nematode and mite infections following parasitological examination and treated with this compound are also discussed. The results demonstrated that the registered, recommended 2.5% moxidectin concentration for use in dogs was sufficient to eliminate nematodes and mites in reptiles. Infections with nematodes were successfully treated with a single application. Mite infestations in reptiles were eliminated using a treatment repeated on 3 consecutive days.
authors.affiliation: Department of Zoomorphology, Cytology and Parasitology, Heinrich Heine University, 40225, Düsseldorf, Germany. mehlhorn@uni-duesseldorf.de.
authors.forename: H
authors.initials: H
authors.lastname: Mehlhorn
authors.affiliation: Department of Zoomorphology, Cytology and Parasitology, Heinrich Heine University, 40225, Düsseldorf, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Schmahl
authors.affiliation: Department of Zoomorphology, Cytology and Parasitology, Heinrich Heine University, 40225, Düsseldorf, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Mevissen
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005243:Feces / Q000469:parasitology; D007093:Imidazoles / Q000008:administration & dosage* / Q000627:therapeutic use*; D007306:Insecticides / Q000008:administration & dosage / Q000627:therapeutic use; D018942:Macrolides / Q000008:administration & dosage / Q000627:therapeutic use; D051379:Mice; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D000073943:Neonicotinoids; D009574:Nitro Compounds / Q000008:administration & dosage* / Q000627:therapeutic use*; D012104:Reptiles / Q000469:parasitology*; D014258:Trichuris
chemical_list: D000871:Anthelmintics; D007093:Imidazoles; D007306:Insecticides; D018942:Macrolides; D000073943:Neonicotinoids; D009574:Nitro Compounds; C082359:imidacloprid; C027837:moxidectin