title: Secondary signet-ring cell tumour of the prostate derived from a primary gastric malignancy.
abstract: Primary signet-ring cell carcinoma of the prostate is infrequent and even more so as secondary spread of this pathologic sub-type to the prostate. We describe the sixth reported case with a diagnosis of a secondary signet-ring cell tumour of the prostate secondary to a gastric cancer. Five years post-gastrectomy to resect signet-ring cell carcinoma, we detected a secondary intra-prostatic spread with urinary tract obstruction. The physical appearance of the tumour cells was similar to that of the previously-resected signet-cell carcinoma of the stomach. There were no metastases in other sites and the patient was treated with radiotherapy. When confronted with intra-prostatic signet-ring cell adenocarcinoma it is necessary to distinguish between primary and secondary aetiology since this would reflect in the choice of treatment and prognosis.
authors.affiliation: Servicio de Oncología Médica, Hospital Regional Universitario Carlos Haya, Avda. Carlos Haya s/n, 29010 Málaga, Spain. mangel.cobo.sspa@juntadeandalucia.es
authors.forename: Manuel
authors.initials: M
authors.lastname: Cobo Dols
authors.forename: Santiago
authors.initials: S
authors.lastname: Muñoz Gallardo
authors.forename: José
authors.initials: J
authors.lastname: Peláez Angulo
authors.forename: Rosa
authors.initials: R
authors.lastname: Algarra García
authors.forename: Carlos
authors.initials: C
authors.lastname: Fuente Lupiáñez
authors.forename: Silvia
authors.initials: S
authors.lastname: Gil Calle
authors.forename: Ester
authors.initials: E
authors.lastname: Villar Chamorro
authors.forename: Alvaro
authors.initials: A
authors.lastname: Montesa Pino
authors.forename: Julia
authors.initials: J
authors.lastname: Alcaide García
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Ales Díaz
authors.forename: Vanesa
authors.initials: V
authors.lastname: Gutiérrez Calderón
authors.forename: Francisco
authors.initials: F
authors.lastname: Carabante Ocón
authors.forename: Manuel
authors.initials: M
authors.lastname: Benavides Orgaz
mesh_terms: D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D013274:Stomach Neoplasms / Q000473:pathology*