title: [Microbiological evaluation of 1% silver sulfadiazine dressings].
abstract: This study aimed at evaluating the microbial condition and antimicrobial activity of 1% silver sulfadiazine dressings used in burns, prepared in advance of the dressing change and stored for 12 to 60 hours before usage. The microbial condition was evaluated by means of three cultures prepared from the Letheen Broth (Difco) culture medium and incubated at 32-35 degrees C for 20 days. Antimicrobial activity was evaluated by means of the diffusion technique of one dressing culture in hospital strains, initially incubated at room temperature and then at 37 degrees C, for 18-24 hours. All three cultures of 12, 36 and 60 hours proved negative. Concerning antimicrobial activity, the zones of inhibition were: 2.25 mm for S. aureus; 2.65 mm for P. aeruginosa and 2.95 mm for E. coli. These dressings can be safely prepared by nurses and stored, reducing nurses' time spent for dressing change and, consequently, patients' exposure.
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo.
authors.forename: Alessandra Cristina Olhan
authors.initials: AC
authors.lastname: Ragonha
authors.forename: Enéas
authors.initials: E
authors.lastname: Ferreira
authors.forename: Denise de
authors.initials: Dd
authors.lastname: Andrade
authors.forename: Lídia Aparecida
authors.initials: LA
authors.lastname: Rossi
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001458:Bandages / Q000382:microbiology*; D002056:Burns / Q000188:drug therapy; D006801:Humans; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D012837:Silver Sulfadiazine