title: Composition of energy metabolism substrates increases the efficiency of pharmacotherapy of cardiovascular diseases.
abstract: The substrate composition containing succinic acid, substrates for succinate synthesis, and antioxidants increased the efficiency of pharmacotherapy in patients with coronary heart disease and hypertension. We revealed an increase in the quality of life and decrease in the functional class of heart failure, incidence of arrhythmias and exercise-related pain, and blood cholesterol concentration.
authors.affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow.
authors.forename: A B
authors.initials: AB
authors.lastname: Peskov
authors.forename: E I
authors.initials: EI
authors.lastname: Maevskii
authors.forename: M L
authors.initials: ML
authors.lastname: Uchitel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000188:drug therapy / Q000378:metabolism; D004359:Drug Therapy, Combination; D004734:Energy Metabolism; D005080:Exercise Test; D005260:Female; D006331:Heart Diseases / Q000188:drug therapy / Q000378:metabolism; D006333:Heart Failure / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000378:metabolism; D007552:Isotonic Solutions / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000378:metabolism; D010809:Physical Fitness; D011788:Quality of Life; D013379:Substrate Specificity
chemical_list: D007552:Isotonic Solutions; C507871:kardiobalans; D002784:Cholesterol