title: Ceramic corundum materials with modified surface as implantation materials.
abstract: Investigations on implants have proved that not only the kind of material structure, but also the surface character of grafts influences the local reaction of biomaterials. In recent years electrochemical reactions on implants surface leading to the so called zeta potential arouse interests. Applications of these properties has made us carry on experiments on use of biomaterials with active potential on their bio-compatibility. The aim of this work is evaluation of influence of electrical charge with zeta potentials character on the local reaction of bone tissue after implantation. Two kinds of ceramics were used in experiments: solid and solid-silane with active surface. Implantation experiments were made on 20 rabbits. Selections were carried of 12, 26, 36 and 54 weeks after implantation of the tested materials. After implantation of solid ceramics, not only bone tissue but also fibrous tissue was observed around the graft. But in case of solid silane ceramics, in all terms of tests, bone tissue tightly sticking to the implant was observed around the graft. Investigations of electrokinetic zeta potential carried out 36 and 54 weeks after implantation showed that the values of that potential originally introduced on the grafts surface were maintained on stable level. The carried out investigations confirmed that activation of implants surface through silaning with sol-gel method allows to introduce the planned zeta potential depending on the characteristic for a given kind of tissue.
authors.affiliation: Department of Experimental Surgery and Biomaterials of Wrocław Medical University.
authors.forename: Robert
authors.initials: R
authors.lastname: Lewandowski
authors.forename: Roman
authors.initials: R
authors.lastname: Rutowski
authors.forename: Danuta
authors.initials: D
authors.lastname: Paluch
authors.forename: Jolanta
authors.initials: J
authors.lastname: Staniszewska-Kuś
authors.forename: Beata
authors.initials: B
authors.lastname: Zboromirska-Wnukiewicz
authors.forename: Adam
authors.initials: A
authors.lastname: Sokolowski
authors.forename: Bogusława
authors.initials: B
authors.lastname: Zywicka
authors.forename: Jan
authors.initials: J
authors.lastname: Wnukiewicz
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry*; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry*; D004563:Electrochemistry; D005260:Female; D008297:Male; D019736:Prostheses and Implants; D011817:Rabbits; D013499:Surface Properties; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D000537:Aluminum Oxide