title: Capillary hemangioblastoma of soft tissue: report of a case and review of the literature.
abstract: Capillary hemangioblastoma (CH) is a tumor of unknown histogenesis that arises primarily in the posterior cranial fossa, either as a sporadic event or in association with von Hippel-Lindau disease. To date, only 6 examples of a tumor with morphological features of CH arising in the somatic soft tissues have been documented in case reports and small series, and 3 of these tumors were associated with a peripheral nerve. Herein, we report a case of CH arising in the gastrocnemius muscle and not associated with a peripheral nerve in a 53-year-old woman with no clinical stigmata or family history of von Hippel-Lindau disease.
authors.affiliation: Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Patton
authors.forename: Robert L
authors.initials: RL
authors.lastname: Satcher
authors.forename: William B
authors.initials: WB
authors.lastname: Laskin
mesh_terms: D018952:Antigens, CD34 / Q000378:metabolism; D044383:Black People / Q000235:genetics; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D026122:Factor XIIIa / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D018325:Hemangioblastoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D007265:Inhibins / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism; D011859:Radiography; D009418:S100 Proteins / Q000378:metabolism; D017154:Stromal Cells / Q000473:pathology / Q000648:ultrastructure; D013997:Time Factors; D016896:Treatment Outcome; D014746:Vimentin / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D009418:S100 Proteins; D014746:Vimentin; C094377:inhibin-alpha subunit; D007265:Inhibins; D026122:Factor XIIIa; D010751:Phosphopyruvate Hydratase