A case of acute humoral rejection in liver transplantation: successful treatment with plasmapheresis and mycophenolate mofetil.
We present a case of a 23-year-old female who underwent orthotopic liver transplantation (OLTx) for biliary atresia, 22 years after a failed Kasai operation. Unusually, her postoperative course was complicated by severe acute humoral rejection. In this case report, we discuss her management as well as the role of plasmapheresis in treating allograft dysfunction secondary to acute humoral rejection in liver transplant patients.
Rostron
Anthony
A
Liver Unit, Freeman Hospital, Newcastle upon Tyne, UK. tonyrostron@doctors.org.uk
Carter
Vaughan
V
Mutunga
Mbithe
M
Cavanagh
Gary
G
O'Suilleabhain
Criostoir
C
Burt
Alistair
A
Jaques
Bryon
B
Talbot
David
D
Manas
Derek
D
D000208:Acute Disease; D000328:Adult; D000917:Antibody Formation; D001656:Biliary Atresia / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D016031:Liver Transplantation; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D010956:Plasmapheresis
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid