Sodium chloride enhanced oligomerization of L-glutamic acid in aqueous solution.
The presence of NaCl was found to significantly enhance the formation of longer peptides in N,N'-carbonyldiimidazole induced oligomerization of L-glutamic acid in homogeneous aqueous solution. The enhancement was detected in the presence of as low as 0.01-M NaCl and the highest yield of longer oligomers was achieved in the presence of 1-M NaCl. The possible prebiotic relevance is discussed.
Wang
Kong-Jiang
KJ
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. wangkj@moon.ibp.ac.cn
Yao
Nan
N
Li
Chen
C
D002851:Chromatography, High Pressure Liquid; D019418:Evolution, Chemical; D018698:Glutamic Acid / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D007700:Kinetics; D000069497:Origin of Life; D011108:Polymers / Q000138:chemical synthesis*; D012965:Sodium Chloride / Q000737:chemistry*
D007093:Imidazoles; D011108:Polymers; D018698:Glutamic Acid; D012965:Sodium Chloride; C006900:N,N-carbonyldiimidazole