Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue.
A new NMR parameter is suggested as a sensitive tool for monitoring thermal coagulation of liver tissue. That parameter is the proton magnetization exchange time (tau(MEX)) between water and the proteins. tau(MEX) was very sensitive to coagulation and insensitive to temperature, therefore representing only damage to the tissue, independent of effects caused by temperature fluctuations. The measurement of tau(MEX) by two different methods revealed the existence of two or more groups of proteins, characterized by their different transverse relaxation time, and tau(MEX).
Carasso
Dina
D
School of Chemistry, Tel Aviv University, Tel Aviv, Israel.
Eliav
Uzi
U
Navon
Gil
G
D000465:Algorithms; D000818:Animals; D001777:Blood Coagulation / Q000502:physiology*; D001798:Blood Proteins / Q000378:metabolism*; D006358:Hot Temperature / Q000627:therapeutic use*; D066298:In Vitro Techniques; D017075:Laser Coagulation / Q000379:methods*; D008099:Liver / Q000378:metabolism* / Q000601:surgery*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011522:Protons; D013552:Swine; D016896:Treatment Outcome
D001798:Blood Proteins; D011522:Protons