Scrotal mass with fever and generalized lymphadenopathy in a young man secondary to Chlamydia trachomatis infection.
A young man presented with systemic upset and generalised lymphadenopathy. Later, it transpired that he was under investigation for a scrotal mass. Investigations were carried out to ascertain the cause of his symptoms including lymph node biopsy. Because of the presence of a scrotal mass in a sexually active male, a urinary Chlamydia ligase chain reaction (LCR) test was carried out. The result was positive and he was treated with doxycycline for 2 weeks. His symptoms settled and further, the urinary LCR was negative. We propose that Chlamydia trachomatis infection caused his illness and that urine PCR or LCR tests for Chlamydia is a convenient and useful investigation in sexually active males with generalised lymphadenopathy and fever of unknown origin.
Jenkins
N E
NE
Tropical and Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.
Radcliffe
L
L
Beadsworth
Mike
M
Mallinson
H
H
Nye
Fred
F
Beeching
Nick
N
D000328:Adult; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D004604:Elephantiasis / Q000209:etiology* / Q000473:pathology; D005334:Fever / Q000209:etiology*; D005832:Genital Diseases, Male / Q000209:etiology / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D012611:Scrotum / Q000473:pathology*; D014556:Urine / Q000382:microbiology