title: Improvement of islet culture with sericin.
abstract: Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerated the proliferation of the rat insulinoma cell line RIN-5F and improved the serum-free culture of rat islets.
authors.affiliation: Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1, Bunkyo, Fukui 910-8507, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Ogawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Terada
authors.forename: Takanori
authors.initials: T
authors.lastname: Kanayama
authors.forename: Masao
authors.initials: M
authors.lastname: Miki
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Morikawa
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Kimura
authors.forename: Akio
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sasaki
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Yamada