title: Bio-guided isolation of the cytotoxic corytenchine and isocoreximine from roots of Annona cherimolia.
abstract: The roots of Annona cherimolia have been shown to contain the known tetrahydroprotoberberine alkaloids corytenchine (1) and isocoreximine (2), investigated for their cytotoxic properties.
authors.affiliation: Instituto de Química, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, México, D.F. México.
authors.forename: Mariano
authors.initials: M
authors.lastname: Martínez-Vázquez
authors.forename: Diana G
authors.initials: DG
authors.lastname: De la Cueva Lozano
authors.forename: Rosa
authors.initials: R
authors.lastname: Estrada-Reyes
authors.forename: Nadia Margarita
authors.initials: NM
authors.lastname: González-Lugo
authors.forename: Teresa
authors.initials: T
authors.lastname: Ramírez Apan
authors.forename: Gerardo
authors.initials: G
authors.lastname: Heinze
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology*; D031041:Annona / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D001600:Berberine Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; C507790:corytenchine; C507791:isocoreximine