title: Microbiology of acute otitis media with tympanostomy tubes.
abstract: OBJECTIVE
  The objective was to determine the types of organisms which cause acute otitis media with a tympanostomy tube and to ascertain their frequency distribution.
  
  
  METHODS
  Prospective, randomized, multi-institutional clinical trials. Both private and academic sites were included.
  
  
  RESULTS
  1309 isolates were recovered from 956 draining ears. Streptococcus pneumonia was recovered from 17%, Staphylococcus aureus from 13%, H flu from 18% and Pseudomonas aeruginosa from 12%. Fungal organisms were recovered from 5% of total isolates and 4% from single isolates.
  
  
  CONCLUSIONS
  AOMT is microbiologically different than AOM with an intact TM. There is no evidence that resistance develops as result of topical treatment.
  
  
  CONCLUSIONS
  The study demonstrates that AOMT is frequently caused by organisms not susceptible to oral antibiotics approved for children, but which are sensitive to topical ear drops.
authors.affiliation: Department of Otolaryngology, UT Southwestern Medical Center, Dallas, TX 75390, USA. peter.roland@utsouthwestern.edu
authors.forename: Peter S
authors.initials: PS
authors.lastname: Roland
authors.forename: David A
authors.initials: DA
authors.lastname: Parry
authors.forename: David W
authors.initials: DW
authors.lastname: Stroman
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008876:Middle Ear Ventilation; D010033:Otitis Media / Q000382:microbiology* / Q000628:therapy; D012621:Seasons; D017211:Treatment Failure