Clonal monosomy 7 in a megakaryoblastic leukemia developed on the basis of Fanconi anemia.
A 13-year-old girl with a history of Fanconi anemia developed acute myeloid leukemia of the M7 subtype with a 45,XX,-7 karyotype, which is rare in M7 subtype. Treatment protocols were set up, but she died of sepsis and osteomyelitis during induction.
Yilmaz
Zerrin
Z
Baskent University Faculty of Medicine, Department of Medical Genetics, Ankara, Turkey.
Alioğlu
Bülent
B
Ozalp
Ozge
O
Yilmaz
Başak Taburoğlu
BT
Ozyürek
Hatice Emel
HE
Ozbek
Namik
N
Sahin
Feride Iffet
FI
D000293:Adolescent; D045930:Anabolic Agents / Q000627:therapeutic use; D002869:Chromosome Aberrations; D002897:Chromosomes, Human, Pair 7; D004359:Drug Therapy, Combination; D005199:Fanconi Anemia / Q000188:drug therapy / Q000235:genetics*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007947:Leukemia, Megakaryoblastic, Acute / Q000235:genetics*; D009006:Monosomy; D010110:Oxymetholone / Q000627:therapeutic use
D045930:Anabolic Agents; D005938:Glucocorticoids; D010110:Oxymetholone