[Novel functions of the well-known protein--prothymosin alpha is involved in protection of cells against apoptosis and oxidative stress].
Several novel functions of the well-known and intensively studied protein prothymosin alpha have recently been revealed. In addition to such traditional functions of this protein as immunomodulatory activity and stimulation of cellular proliferation, prothymosin alpha was shown to be involved in protection of cells against apoptosis and in regulation of expression of the oxidative stress-protective genes. Methods and approaches used for revelation of prothymosin alpha novel functions are described in this review.
Evstaf'eva
A G
AG
Karapetian
R N
RN
Rubtsov
Iu P
IuP
Filonov
G S
GS
Abaeva
I S
IS
Fateeva
T V
TV
Mel'nikov
S V
SV
Chichkova
N V
NV
Vartapetian
A B
AB
D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D018384:Oxidative Stress; D011498:Protein Precursors / Q000235:genetics / Q000502:physiology*; D013947:Thymosin / Q000031:analogs & derivatives* / Q000235:genetics / Q000502:physiology; D015533:Transcriptional Activation
D011498:Protein Precursors; C040782:prothymosin alpha; D013947:Thymosin