[Feminizing testicular syndrome with multiple hamartomas and bilateral paratesticular leiomyomas].
BACKGROUND
Complete androgen insensitivity syndrome or testicular feminization syndrome (TF) is the most common form of male pseudohermaphrodism, caused by a failure of androgen receptor binding. Patient with male genotype 46 XY, has a female morphotype with well developed external sexual organs.


METHODS
- We report the case of a 29 year-old girl with a TF syndrome discovered during the exploration of a primary amenorrhoea. Bilateral orchidectomy was performed. The testis were immature; they showed bilateral leiomyoma of the tunica albuginea and multiple hamartomas on the right side.


CONCLUSIONS
Benign tumors are developped in 80% of cases of TF and they are generally hamartomatous nodules of testis. Association of paratesticular leiomyoma to synchronous hamartoma has never been described, its histogenesis is discussed.
Krichen Makni
S
S
Service d'anatomie et de cytologique pathologiques, CHU H. Bourguiba, 3029, Sfax, Tunisie. akabdelmajid@yahoo.fr
Mnif Hachicha
L
L
Ellouze
S
S
Mnif
M
M
Khabir
A
A
Ketata
H
H
Abid
M
M
Sellami Boudawara
T
T
D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D013734:Androgen-Insensitivity Syndrome; D005260:Female; D007839:Functional Laterality; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D008297:Male; D013736:Testicular Neoplasms / Q000473:pathology*