title: Extensive persistent pupillary membranes: conservative management.
abstract: Extensive persistent pupillary membranes (PPMS) may appear to occlude the pupil so completely as to preclude useful vision. They often motivate aggressive interventions. We present a 6-year-old girl with bilateral extensive densely pigmented pupillary membranes in whom good vision was obtained without pharmacologic, laser, or surgical intervention. There was associated ametropic amblyopia and exotropia in the patient, which were effectively treated with spectacles and occlusion therapy, with the patient responding conventionally. In view of our findings, we recommend a trial of conservative management before surgical intervention even in cases of dense PPMs.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute, University of California-Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095-7002, USA.
authors.forename: Neepa M
authors.initials: NM
authors.lastname: Thacker
authors.forename: Michelle T
authors.initials: MT
authors.lastname: Brit
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Demer
mesh_terms: D002648:Child; D005139:Eyeglasses; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007498:Iris / Q000002:abnormalities*; D007499:Iris Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D008566:Membranes; D012029:Refraction, Ocular; D012683:Sensory Deprivation; D012720:Severity of Illness Index; D014792:Visual Acuity