title: Evaluation of central serous retinopathy with en face optical coherence tomography.
abstract: BACKGROUND
  The diagnosis of idiopathic central serous retinopathy (CSR) is usually based on biomicroscopy and fluorescein angiography (FA). The optical coherence tomography (OCT) ophthalmoscope produces en face OCT scans (OCT C-scans) and provides additional information not readily available by conventional imaging techniques. The authors describe the characteristic features observed in patients with a clinical diagnosis of CSR using the OCT ophthalmoscope.
  
  
  METHODS
  38 eyes with a clinical diagnosis of CSR, seen at the Academic Medical Centre (Amsterdam, Netherlands) and the New York Eye and Ear Infirmary (New York, USA) between August 2002 and March 2004, were evaluated with standard digital FA and scanned with the OCT ophthalmoscope.
  
  
  RESULTS
  Nine of 38 eyes had no serous neurosensory detachment (inactive CSR) when scanned with the OCT ophthalmoscope. Characteristics for active CSR (n=29) were large neurosensory detachment (23/29), subretinal hyper-reflective depoits (20/29), and pigment epithelial detachment (15/29). One third of the patients, either active or inactive, had multiple small pigment epithelial detachments located both within and outside the neurosensory detachment.
  
  
  CONCLUSIONS
  The OCT ophthalmoscope provides complementary morphological information on patients with CSR. The presence of more diffuse retinal pigment epithelium (RPE) changes lends further support to the concept that CSR is a diffuse rather than localised RPE anomaly.
authors.affiliation: Department of Ophthalmology, Academic Medical Centre, PO Box 22660, 1100 DD Amsterdam, Netherlands. m.e.vanvelthoven@amc.uva.nl
authors.forename: M E J
authors.initials: ME
authors.lastname: van Velthoven
authors.forename: F D
authors.initials: FD
authors.lastname: Verbraak
authors.forename: P M
authors.initials: PM
authors.lastname: Garcia
authors.forename: R O
authors.initials: RO
authors.lastname: Schlingemann
authors.forename: R B
authors.initials: RB
authors.lastname: Rosen
authors.forename: M D
authors.initials: MD
authors.lastname: de Smet
mesh_terms: D000208:Acute Disease; D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis* / Q000473:pathology; D002908:Chronic Disease; D003941:Diagnostic Techniques, Ophthalmological; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012163:Retinal Detachment / Q000175:diagnosis* / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods*