title: Transition-metal-catalyzed sequential cross-coupling of bis(iodozincio)methane and -ethane with two different organic halides.
abstract: Bis(iodozincio)methane, prepared from diiodomethane and zinc, reacts with an organic halide in the presence of a transition-metal catalyst to give an iodozinciomethylenated compound; this then reacts with another organic halide to form a C--C bond. The overall process connects two electrophiles with one carbon atom. Bis(iodozincio)ethane can also undergo this transformation, yielding a new stereogenic center. The asymmetric induction of this stereogenic center was investigated by using a chiral palladium catalyst.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoudai-katsura, Nishikyo, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yoshino
authors.forename: Narihiro
authors.initials: N
authors.lastname: Toda
authors.forename: Masami
authors.initials: M
authors.lastname: Kobata
authors.forename: Katsumi
authors.initials: K
authors.lastname: Ukai
authors.forename: Koichiro
authors.initials: K
authors.lastname: Oshima
authors.forename: Kiitiro
authors.initials: K
authors.lastname: Utimoto
authors.forename: Seijiro
authors.initials: S
authors.lastname: Matsubara
mesh_terms: D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
chemical_list: D006846:Hydrocarbons, Halogenated; C513531:bis(iodozincio)methane; D010165:Palladium; D008697:Methane