title: Role of lipooligosaccharide in the attachment of Moraxella catarrhalis to human pharyngeal epithelial cells.
abstract: The goal of this study was to determine the role of lipooligosaccharide in the attachment of Moraxella catarrhalis to human pharyngeal epithelial cells. Strain 2951 and its P(k) mutant strain 2951 galE were used in this study. This study suggests that the P(k) epitope of LOS is not an adhesin for M. catarrhalis, but plays a crucial role by its surface charge in the initial stage of attachment.
authors.affiliation: Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
authors.forename: Gulcan
authors.initials: G
authors.lastname: Akgul
authors.forename: Ali
authors.initials: A
authors.lastname: Erturk
authors.forename: Mustafa
authors.initials: M
authors.lastname: Turkoz
authors.forename: Tolga
authors.initials: T
authors.lastname: Turan
authors.forename: Akitoyo
authors.initials: A
authors.lastname: Ichinose
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Nagatake
authors.forename: Kamruddin
authors.initials: K
authors.lastname: Ahmed
mesh_terms: D018829:Adhesins, Bacterial / Q000502:physiology*; D001422:Bacterial Adhesion / Q000502:physiology*; D002460:Cell Line; D004847:Epithelial Cells / Q000382:microbiology*; D006801:Humans; D008070:Lipopolysaccharides / Q000378:metabolism*; D001936:Moraxella catarrhalis / Q000472:pathogenicity* / Q000502:physiology; D010614:Pharynx / Q000166:cytology / Q000382:microbiology*; D011135:Polysaccharides, Bacterial / Q000502:physiology*
chemical_list: D018829:Adhesins, Bacterial; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; C055239:bacterial adhesins, polysaccharide; C023023:lipid-linked oligosaccharides