title: Microbial experiments on adaptive landscapes.
abstract: The adaptive landscape is one of the most widely used metaphors in evolutionary biology. It is created by plotting fitness against phenotypes or genotypes in a given environment. The shape of the landscape is crucial in predicting the outcome of evolution: whether evolution will result in populations reaching predictable end points, or whether multiple evolutionary outcomes are more likely. In a more applied sense, the landscape will determine whether organisms will evolve to lose 'costly' resistance to antibiotics, herbicides or pesticides when the use of the control agent is stopped. Laboratory populations of microbes allow evolution to be observed in real time and, as such, provide key insights into the topology of adaptive landscapes.
authors.affiliation: Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Colegrave
authors.forename: Angus
authors.initials: A
authors.lastname: Buckling
mesh_terms: D000220:Adaptation, Biological; D005075:Biological Evolution; D004777:Environment; D008829:Microbiology; D008957:Models, Genetic