title: Short- and long-term outcomes of patients with electrocardiographic left ventricular hypertrophy after fibrinolysis for acute myocardial infarction.
abstract: There is conflicting evidence with regard to the value of electrocardiographic left ventricular hypertrophy (LVH) in myocardial infarction. Of 5,951 patients in the ASSENT-3 trial, 273 (5%) had LVH on baseline electrocardiograms and had significantly higher mortality rates at 30 days (11% vs 6%, p = 0.001) and 1 year (13% vs 8%, p = 0.007). After adjustment for differences in baseline parameters, LVH remained an independent predictor of 30-day (hazard ratio 2.3, 95% confidence interval 1.4 to 3.9) and 1-year (hazard ratio 1.8, 95% confidence interval 1.1 to 2.8) mortality rates. Thus, electrocardiographic LVH is a prognostic tool in identifying short- and long-term mortality rates in patients who have ST-elevation myocardial infarction and receive fibrinolysis.
authors.affiliation: Canadian Heart Research Centre, Toronto, Ontario, Canada.
authors.forename: Alina
authors.initials: A
authors.lastname: Georgescu
authors.forename: Yuling
authors.initials: Y
authors.lastname: Fu
authors.forename: Cynthia
authors.initials: C
authors.lastname: Yau
authors.forename: Quamrul
authors.initials: Q
authors.lastname: Hassan
authors.forename: Janna
authors.initials: J
authors.lastname: Luchansky
authors.forename: Paul W
authors.initials: PW
authors.lastname: Armstrong
authors.forename: Galen
authors.initials: G
authors.lastname: Wagner
authors.forename: Frans
authors.initials: F
authors.lastname: Van de Werf
authors.forename: Shaun G
authors.initials: SG
authors.lastname: Goodman
mesh_terms: D004562:Electrocardiography; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000209:etiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy*; D015425:Myocardial Reperfusion; D011379:Prognosis; D013997:Time Factors