title: Shape adaptation of long bone structures using a contour based approach.
abstract: In this work, an approach for mechanically driven shape adaptation of long bone structures is presented which utilizes contour descriptions to track morphological changes at different bone cross sections. A script-based procedure is used to iteratively generate a solid geometry and finite element (FE) model from these contours, perform a stress analysis, and then update the contour shapes using the results of the stress analysis using a prescribed remodeling rule. Because a remeshing operation is performed at each timestep the method is able to effectively simulate large changes in geometry. Several examples of shape adaptation of idealized and geometrically accurate long-bone structures are presented using a variety of remodeling signals and parameters.
authors.affiliation: Tulane University, Department of Biomedical Engineering, New Orleans, LA, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Roberts
authors.forename: R T
authors.initials: RT
authors.lastname: Hart
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D001842:Bone and Bones / Q000033:anatomy & histology* / Q000502:physiology*; D003198:Computer Simulation; D008953:Models, Anatomic; D008954:Models, Biological; D051381:Rats; D013977:Tibia / Q000033:anatomy & histology / Q000502:physiology