Early histology in ankylosing spondylitis related spondylodiscitis supports its inflammatory origin.
It is unclear whether the destructive lesions of the vertebral bodies in the spondylodiscitis of ankylosing spondylitis (AS) are related to mechanical stress or inflammation. We describe early immunohistopathological findings in an AS patient with severe symptomatic spondylodiscitis that support an inflammatory origin.
Nikolaisen
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Department of Rheumatology, University-Hospital Northern Norway, Tromsø, Norway. Cathrin.Nikolaisen@unn.no
Nossent
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D001706:Biopsy; D015299:Discitis / Q000209:etiology / Q000276:immunology* / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000276:immunology* / Q000473:pathology*; D013904:Thoracic Vertebrae / Q000276:immunology / Q000473:pathology