title: The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk.
abstract: Viral load and drug levels were measured in the plasma and breast milk of nine mothers treated with highly active antiretroviral therapy (HAART) and one woman treated only with zidovudine during delivery. In all HAART-treated women after delivery the viral load was less than 400 copies/ml in plasma and breast milk. Compared with the plasma concentration, the breast milk concentration was between 68 and 90% for nevirapine, 6 and 24% for nelfinavir and 90 and 540% for indinavir.
authors.affiliation: Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
authors.forename: Robert
authors.initials: R
authors.lastname: Colebunders
authors.forename: Beata
authors.initials: B
authors.lastname: Hodossy
authors.forename: David
authors.initials: D
authors.lastname: Burger
authors.forename: Tania
authors.initials: T
authors.lastname: Daems
authors.forename: Kristien
authors.initials: K
authors.lastname: Roelens
authors.forename: Marc
authors.initials: M
authors.lastname: Coppens
authors.forename: Ben
authors.initials: B
authors.lastname: Van Bulck
authors.forename: Yves
authors.initials: Y
authors.lastname: Jacquemyn
authors.forename: Eric
authors.initials: E
authors.lastname: Van Wijngaerden
authors.forename: Katrien
authors.initials: K
authors.lastname: Fransen
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000378:metabolism*; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D008895:Milk, Human / Q000737:chemistry*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents