title: [Novel functions of the well-known protein--prothymosin alpha is involved in protection of cells against apoptosis and oxidative stress].
abstract: Several novel functions of the well-known and intensively studied protein prothymosin alpha have recently been revealed. In addition to such traditional functions of this protein as immunomodulatory activity and stimulation of cellular proliferation, prothymosin alpha was shown to be involved in protection of cells against apoptosis and in regulation of expression of the oxidative stress-protective genes. Methods and approaches used for revelation of prothymosin alpha novel functions are described in this review.
authors.forename: A G
authors.initials: AG
authors.lastname: Evstaf'eva
authors.forename: R N
authors.initials: RN
authors.lastname: Karapetian
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Rubtsov
authors.forename: G S
authors.initials: GS
authors.lastname: Filonov
authors.forename: I S
authors.initials: IS
authors.lastname: Abaeva
authors.forename: T V
authors.initials: TV
authors.lastname: Fateeva
authors.forename: S V
authors.initials: SV
authors.lastname: Mel'nikov
authors.forename: N V
authors.initials: NV
authors.lastname: Chichkova
authors.forename: A B
authors.initials: AB
authors.lastname: Vartapetian
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D018384:Oxidative Stress; D011498:Protein Precursors / Q000235:genetics / Q000502:physiology*; D013947:Thymosin / Q000031:analogs & derivatives* / Q000235:genetics / Q000502:physiology; D015533:Transcriptional Activation
chemical_list: D011498:Protein Precursors; C040782:prothymosin alpha; D013947:Thymosin