Sesquiterpene lactones from Centaurea musimomum. Antiplasmodial and cytotoxic activities.
The chloroform extract of the aerial parts of Centaurea musimomum exhibited significant activity against Plasmodium falciparum. The phytochemical study of this extract gave seven native and four acetylated sesquiterpene lactones.
Medjroubi
Kamel
K
Département de Chimie, Faculté des Sciences, Université Mentouri de Constantine, Route de Aïn El Bey 25000, Constantine, Algérie.
Benayache
Fadila
F
Bermejo
Jaime
J
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification / Q000494:pharmacology*; D000981:Antiprotozoal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D031179:Centaurea / Q000737:chemistry*; D007783:Lactones / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010963:Plasmodium falciparum / Q000187:drug effects; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D000981:Antiprotozoal Agents; D007783:Lactones; D010936:Plant Extracts; D012717:Sesquiterpenes