Cryptococcal fungemia in a neutropenic patient with AIDS while receiving caspofungin.
Empiric choice of anti-fungal therapy in febrile neutropenia should be based upon a host's susceptibility to specific fungal pathogens. We present a case of a patient with multiple risk factors for fungemia including HIV infection, Hodgkin's disease, corticosteroid use and chemotherapy-induced neutropenia who developed disseminated cryptococcal infection while receiving caspofungin.
Malhotra
Prashant
P
North Shore University Hospital, Manhasset, NY 11030, USA.
Shah
Sanjiv S
SS
Kaplan
Mark
M
McGowan
Joseph P
JP
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000077336:Caspofungin; D003453:Cryptococcosis / Q000150:complications / Q000382:microbiology; D003455:Cryptococcus neoformans / Q000187:drug effects / Q000302:isolation & purification*; D025141:Drug Resistance, Fungal; D054714:Echinocandins; D016469:Fungemia / Q000150:complications* / Q000382:microbiology; D015658:HIV Infections / Q000150:complications*; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D055666:Lipopeptides; D009181:Mycoses / Q000517:prevention & control; D009503:Neutropenia / Q000150:complications*; D010456:Peptides, Cyclic / Q000008:administration & dosage / Q000627:therapeutic use*
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D000077336:Caspofungin