A thieno-2H-chromene alpha-amino acid derivative: synthesis and photochromic properties.
[structure: see text] A new photochromic thieno-2H-chromene alpha-amino acid derivative was prepared by C-N palladium-catalyzed cross-coupling of a bromothieno-2H-chromene with the aminated aromatic side chain of the methyl ester of a N,N-diprotected amino acid. Its good photochromic properties demonstrated by flash photolysis and continuous irradiation indicate a possible application in ophthalmic lenses. It may also be inserted into peptides to give photoinduced reversible structural changes.
Queiroz
Maria-João R P
MJ
Departamento de Química, Universidade do Minho, Campus de Gualtar, Braga, Portugal. mjrpq@quimica.uminho.pt
Abreu
Ana S
AS
Ferreira
Paula M T
PM
Oliveira
M Manuel
MM
Dubest
Roger
R
Aubard
Jean
J
Samat
André
A