title: Long-term follow-up of a patient with Kawasaki disease and coronary aneurysm associated with asymptomatic thrombosis: a case report.
abstract: A 20-year-old male was first diagnosed with Kawasaki disease at age 2 years 9 months. Coronary angiography in the acute phase revealed coronary aneurysms, so chronic antiplatelet therapy was initiated with aspirin and ticlopidine. The patient was asymptomatic and was followed up. Stress myocardial imaging showed asymptomatic myocardial ischemia at age 20 years. Coronary angiography was performed, and revealed 99% occlusion of the right coronary artery and collateral circulation from the left coronary artery. Occlusion was attributed to coronary aneurysm thrombosis. Much remains unknown about the long-term prognosis in patients with coronary aneurysm associated with Kawasaki disease. Asymptomatic children who are followed up sometimes develop ischemic heart disease as young adults. This case highlights the need for long-term follow-up in patients with Kawasaki disease and coronary aneurysms.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, Yasashi-cho 1197-1, Asahi-ku, Yokohama 241-0811. chaom@nifty.com
authors.forename: Hisao
authors.initials: H
authors.lastname: Matsuda
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Kengo
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Aoyagi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Akashi
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ozawa
authors.forename: Junzo
authors.initials: J
authors.lastname: Nagashima
authors.forename: Haruki
authors.initials: H
authors.lastname: Musha
mesh_terms: D000328:Adult; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology*; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D011379:Prognosis