title: Neurological complications following extrusion of sodium hypochlorite solution during root canal treatment.
abstract: OBJECTIVE
  To report the presentation and management of two cases with neurological complications secondary to the extrusion of sodium hypochlorite solution into the facial soft tissues during root canal treatment.
  
  
  CONCLUSIONS
  The clinical features, with particular emphasis on nerve deficit following inadvertent extrusion of sodium hypochlorite, are discussed and its management highlighted. Early and aggressive treatment is advocated following such incidents in order to reduce potentially serious complications.
  
  
  CONCLUSIONS
  *Neurological sequelae can follow inadvertent hypochlorite extrusion. *Early recognition may avert a potentially more serious outcome. *Active hospital treatment including intravenous steroids and antibiotics is recommended.
authors.affiliation: Maxillofacial Unit, Queen Alexandra Hospital, Portsmouth, UK.
authors.forename: R
authors.initials: R
authors.lastname: Witton
authors.forename: K
authors.initials: K
authors.lastname: Henthorn
authors.forename: M
authors.initials: M
authors.lastname: Ethunandan
authors.forename: S
authors.initials: S
authors.lastname: Harmer
authors.forename: P A
authors.initials: PA
authors.lastname: Brennan
mesh_terms: D000328:Adult; D002610:Cheek / Q000294:innervation; D005155:Facial Nerve Diseases / Q000139:chemically induced*; D005158:Facial Paralysis / Q000139:chemically induced; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006987:Hypesthesia / Q000139:chemically induced; D008046:Lip / Q000294:innervation; D009915:Orbit / Q000294:innervation; D010292:Paresthesia / Q000139:chemically induced; D012388:Root Canal Irrigants / Q000009:adverse effects*; D012390:Root Canal Therapy / Q000009:adverse effects*; D012973:Sodium Hypochlorite / Q000009:adverse effects*
chemical_list: D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite