title: Fertility after laparoscopic colorectal resection for endometriosis: preliminary results.
abstract: OBJECTIVE
  To examine fertility, reproductive outcomes, and determinants of fertility after laparoscopic segmental colorectal resection for endometriosis.
  
  
  METHODS
  Retrospective longitudinal study.
  
  
  METHODS
  Tertiary university gynecology unit.
  
  
  METHODS
  The study population consisted of 34 women with colorectal endometriosis, of whom 22 wished to conceive. Demographic, surgical, and histological characteristics of 10 women who conceived were compared with those of 12 women who failed to conceive.
  
  
  METHODS
  Laparoscopic colorectal resection for endometriosis.
  
  
  METHODS
  Rates of pregnancy and live birth.
  
  
  RESULTS
  Mean follow-up after segmental colorectal resection was 24 months (range 6-42 months), and the pregnancy rate was 45.5%. The median time to conceive was 8 months (range 3-13 months). Twelve pregnancies occurred in 10 women, comprising nine spontaneous singleton pregnancies (7 vaginal deliveries, 1 cesarean section, and 1 ongoing pregnancy), and three pregnancies obtained by IVF (one miscarriage, one ongoing twin pregnancy, and one triplet pregnancy necessitating cesarean section at 29 weeks for premature rupture of the membranes, with two surviving infants). The live birth rate was 82%. The women who did and did not conceive did not differ in terms of mean follow-up, mean age, body mass index (BMI), parity, smoking, use and duration of oral contraception (OC), duration of infertility, or the length of the resected colorectal segment. Uterine adenomyosis was the main determinant of pregnancy after colorectal resection.
  
  
  CONCLUSIONS
  These preliminary results suggest that extensive laparoscopic segmental colorectal resection for endometriosis can enhance fertility, with high rates of spontaneous pregnancy and live birth.
authors.affiliation: Service de Gynécologie, Hôpital Tenon, AP-HP, Paris, France. emile.darai@tnn.ap-hop-paris.fr
authors.forename: Emile
authors.initials: E
authors.lastname: Daraï
authors.forename: Olivier
authors.initials: O
authors.lastname: Marpeau
authors.forename: Isabelle
authors.initials: I
authors.lastname: Thomassin
authors.forename: Gil
authors.initials: G
authors.lastname: Dubernard
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Barranger
authors.forename: Marc
authors.initials: M
authors.lastname: Bazot
mesh_terms: D000328:Adult; D003106:Colon / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D004715:Endometriosis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D050498:Live Birth / Q000453:epidemiology*; D008137:Longitudinal Studies; D012007:Rectum / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies