title: Plasma exchange for primary autoimmune autonomic failure.
abstract: We report on a patient with long-standing severe autonomic failure that affected his sympathetic and parasympathetic nervous systems. Antibodies against the ganglionic acetylcholine receptors were detected in the serum. Removal of the antibodies by means of plasma exchange resulted in a dramatic clinical improvement.
authors.affiliation: Franz Volhard Clinical Research Center and the Max Delbrück Center for Molecular Medicine, Berlin.
authors.forename: Christoph
authors.initials: C
authors.lastname: Schroeder
authors.forename: Steven
authors.initials: S
authors.lastname: Vernino
authors.forename: Andreas L
authors.initials: AL
authors.lastname: Birkenfeld
authors.forename: Jens
authors.initials: J
authors.lastname: Tank
authors.forename: Karsten
authors.initials: K
authors.lastname: Heusser
authors.forename: Axel
authors.initials: A
authors.lastname: Lipp
authors.forename: Thomas
authors.initials: T
authors.lastname: Benter
authors.forename: Carsten
authors.initials: C
authors.lastname: Lindschau
authors.forename: Ralph
authors.initials: R
authors.lastname: Kettritz
authors.forename: Friedrich C
authors.initials: FC
authors.lastname: Luft
authors.forename: Jens
authors.initials: J
authors.lastname: Jordan
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000628:therapy*; D001342:Autonomic Nervous System Diseases / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005725:Ganglia, Autonomic / Q000276:immunology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D010951:Plasma Exchange; D011239:Prednisolone / Q000627:therapeutic use; D011950:Receptors, Cholinergic / Q000276:immunology; D012008:Recurrence; D013575:Syncope / Q000209:etiology / Q000628:therapy
chemical_list: D001323:Autoantibodies; D005938:Glucocorticoids; D011950:Receptors, Cholinergic; D011239:Prednisolone