title: Development of the locomotor system in 2 G exposed rats.
abstract: Several studies have shown the detrimental effects of microgravity exposure on the locomotor development in young rats. The opposite situation, i.e. hypergravity, which strongly stimulates several sensory systems and in particular the vestibular system, has unknown effects on the development of locomotion. This study reports 1) the temporal course of walking development of rats which were conceived and born in 2 g, and subsequently transferred to 1 g at different postnatal ages, and 2) the correlated modifications of soleus and tibialis anterior muscles.
authors.affiliation: Medical Physiology Department, University of Groningen, Groningen, The Netherlands.
authors.forename: Valentine
authors.initials: V
authors.lastname: Bouët
authors.forename: Jos
authors.initials: J
authors.lastname: Ijkema-Paassen
authors.forename: René
authors.initials: R
authors.lastname: Wubbels
authors.forename: Albert
authors.initials: A
authors.lastname: Gramsbergen
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001696:Biomechanical Phenomena; D005260:Female; D006112:Gravitation; D019416:Head Movements / Q000502:physiology; D018471:Hypergravity; D008124:Locomotion / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology; D011247:Pregnancy; D051381:Rats; D013997:Time Factors; D014722:Vestibule, Labyrinth / Q000502:physiology