title: Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue.
abstract: A new NMR parameter is suggested as a sensitive tool for monitoring thermal coagulation of liver tissue. That parameter is the proton magnetization exchange time (tau(MEX)) between water and the proteins. tau(MEX) was very sensitive to coagulation and insensitive to temperature, therefore representing only damage to the tissue, independent of effects caused by temperature fluctuations. The measurement of tau(MEX) by two different methods revealed the existence of two or more groups of proteins, characterized by their different transverse relaxation time, and tau(MEX).
authors.affiliation: School of Chemistry, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Dina
authors.initials: D
authors.lastname: Carasso
authors.forename: Uzi
authors.initials: U
authors.lastname: Eliav
authors.forename: Gil
authors.initials: G
authors.lastname: Navon
mesh_terms: D000465:Algorithms; D000818:Animals; D001777:Blood Coagulation / Q000502:physiology*; D001798:Blood Proteins / Q000378:metabolism*; D006358:Hot Temperature / Q000627:therapeutic use*; D066298:In Vitro Techniques; D017075:Laser Coagulation / Q000379:methods*; D008099:Liver / Q000378:metabolism* / Q000601:surgery*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011522:Protons; D013552:Swine; D016896:Treatment Outcome
chemical_list: D001798:Blood Proteins; D011522:Protons