title: Treatment of anxiety disorders in primary care practice: a randomised controlled trial.
abstract: BACKGROUND
  Anxiety disorders are prevalent in primary care. Psychological treatment is effective but time-consuming, and there are waiting lists for secondary care. Interest has therefore grown in developing guidelines for treatment that would be feasible in primary care.
  
  
  OBJECTIVE
  To compare the effectiveness and feasibility of guided self-help, the Anxiety Disorder Guidelines of the Netherlands College of General Practitioners and cognitive behavioural therapy (CBT).
  
  
  METHODS
  Randomised controlled study lasting 12 weeks with follow-up at 3 and 9 months for primary care patients with panic disorder and/or generalised anxiety disorder.
  
  
  METHODS
  The first two forms of treatment were carried out by 46 GPs who were randomly assigned to one or the other form. CBT was carried out by cognitive behaviour therapists in a psychiatric outpatient clinic.
  
  
  METHODS
  Participants (n = 154) were randomly assigned to one of the three forms of treatment. The main outcome measure used was the state subscale of the Spielberger Anxiety Inventory.
  
  
  RESULTS
  All three forms of treatment gave significant improvement between pre-test and post-test, and this improvement remained stable between post-test and the follow-ups. The results obtained with the three treatment forms did not differ significantly over time. The feasibility of the Anxiety Disorder Guidelines was low compared with that of guided self-help.
  
  
  CONCLUSIONS
  Our results indicate that primary care patients with prevalent anxiety disorders for whom the GP does not find referral necessary can be adequately treated by the GP. Psychiatric outpatient clinic referral does not give superior results. Guided self-help is easier for the GP to carry out than a less highly-structured treatment like that laid down in the Anxiety Disorder Guidelines.
authors.affiliation: Department of Psychiatry, VU University Medical Centre, GGZ Buitenamstel, Amsterdam, The Netherlands.
authors.forename: Christine A
authors.initials: CA
authors.lastname: van Boeijen
authors.forename: Patricia
authors.initials: P
authors.lastname: van Oppen
authors.forename: Anton J L M
authors.initials: AJ
authors.lastname: van Balkom
authors.forename: Sako
authors.initials: S
authors.lastname: Visser
authors.forename: Pieter T
authors.initials: PT
authors.lastname: Kempe
authors.forename: Nettie
authors.initials: N
authors.lastname: Blankenstein
authors.forename: Richard
authors.initials: R
authors.lastname: van Dyck
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000628:therapy*; D001291:Attitude of Health Personnel; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005194:Family Practice / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012648:Self Care / Q000379:methods*; D016896:Treatment Outcome