title: The impact of fatigue on the development of postpartum depression.
abstract: BACKGROUND
  Previous research suggests early postpartum fatigue (PPF) plays a significant role in the development of postpartum depression (PPD). Predicting risk for PPD via early identification of PPF may provide opportunity for intervention.
  
  
  OBJECTIVE
  To replicate and extend previous studies concerning the impact of PPF on symptoms of PPD and to describe the relationships among PPF, PPD, and other variables using the theory of unpleasant symptoms.
  
  
  METHODS
  Correlational, longitudinal study.
  
  
  METHODS
  Participants' homes.
  
  
  METHODS
  Convenience sample of 42 community-dwelling women recruited before 36 weeks of pregnancy.
  
  
  METHODS
  PPF, depressive symptoms, and stress measured during prenatal weeks 36 to 38, and on Days 7, 14, and 28 after childbirth. Salivary cortisol was measured as a physiological marker of stress.
  
  
  RESULTS
  Significant correlations were obtained between PPF and symptoms of PPD on Days 7, 14, and 28, with Day 14 PPF levels predicting future development of PPD symptoms in 10 of 11 women. Perceived stress, but not cortisol, was also correlated with symptoms of PPD on Days 7, 14, and 28. Women with a history of depression had elevated depression scores compared to women without, but no variable was as effective at predicting PPD as PPF.
  
  
  CONCLUSIONS
  Fatigue by Day 14 postpartum was the most predictive variable for symptoms of PPD on Day 28 in this population.
authors.affiliation: College of Nursing, The Ohio State University, 1585 Neil Avenue, Columbus, OH 43210, USA. corwin.56@osu.edu
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Corwin
authors.forename: Jean
authors.initials: J
authors.lastname: Brownstead
authors.forename: Nichole
authors.initials: N
authors.lastname: Barton
authors.forename: Starlet
authors.initials: S
authors.lastname: Heckard
authors.forename: Karen
authors.initials: K
authors.lastname: Morin
mesh_terms: D000328:Adult; D019052:Depression, Postpartum / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D005221:Fatigue / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D008137:Longitudinal Studies; D008960:Models, Psychological; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D011644:Puerperal Disorders / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000150:complications / Q000175:diagnosis / Q000378:metabolism; D013997:Time Factors
chemical_list: D006854:Hydrocortisone