title: Transient serous retinal detachment in classic and occult choroidal neovascularization after photodynamic therapy.
abstract: OBJECTIVE
  To quantify transient serous retinal detachment in classic and occult choroidal neovascularization (CNV) after photodynamic therapy (PDT).
  
  
  METHODS
  Prospective consecutive case series.
  
  
  METHODS
  Consecutive patients with classic and occult CNV were examined by optical coherence tomography before PDT and at 2 and 7 days after PDT.
  
  
  RESULTS
  In classic CNV (n = 6), retinal elevations increased from 217 (SD 42) microm before PDT to 626 (SD 157) microm 2 days after PDT and decreased to 240 (SD 36) microm 7 days after treatment. In occult CNV (n = 4), the mean retinal elevation of 266 (SD 41) microm before PDT increased to 544 (SD 94) microm 2 days after PDT and decreased to 259 (SD 40) microm 7 days after treatment.
  
  
  CONCLUSIONS
  Cross-sectional optical coherence tomography imaging revealed transient subretinal fluid accumulation in classic as well as in occult CNV after PDT. The subretinal location possibly relates to an outer blood-retinal barrier breakdown after PDT.
authors.affiliation: Department of Ophthalmology, Philipps-University, Marburg, Germany. stefan.mennel@lycos.com
authors.forename: Stefan
authors.initials: S
authors.lastname: Mennel
authors.forename: Carsten H
authors.initials: CH
authors.lastname: Meyer
authors.forename: Fred
authors.initials: F
authors.lastname: Eggarter
authors.forename: Silvia
authors.initials: S
authors.lastname: Peter
mesh_terms: D001813:Blood-Retinal Barrier; D020256:Choroidal Neovascularization / Q000188:drug therapy*; D005122:Exudates and Transudates; D006801:Humans; D010778:Photochemotherapy; D011183:Postoperative Complications; D011446:Prospective Studies; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D044967:Serum; D041623:Tomography, Optical Coherence / Q000379:methods