title: Efficient cross-coupling of functionalized arylzinc halides catalyzed by a nickel chloride-diethyl phosphite system.
abstract: [reaction: see text] The combination of diethyl phosphite and DMAP as ligands for nickel in an 8:1 THF-N-ethylpyrrolidinone (NEP) mixture allows a very efficient cross-coupling reaction to be performed between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides. The reaction proceeds at 25 degrees C within 1-48 h and requires only 0.05 mol % of the nickel catalyst.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität, München, Germany.
authors.forename: Andrei
authors.initials: A
authors.lastname: Gavryushin
authors.forename: Christiane
authors.initials: C
authors.lastname: Kofink
authors.forename: Georg
authors.initials: G
authors.lastname: Manolikakes
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel