Testosterone replacement therapy for late onset hypogonadism: what is the risk of inducing prostate cancer?
Prescription sales of testosterone have risen considerably over the last decade and are likely to continue to grow as further preparations become available. Testosterone promotes existing prostate cancer; however, concern does exist as to whether or not testosterone therapy induces prostate cancer. The aim of this article is to review the evidence for such a link.
Gould
D C
DC
The Prostate Centre, Wimpole Street, London, UK. duncangould@hotmail.com
Kirby
R S
RS
D000818:Animals; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D011467:Prostate / Q000187:drug effects*; D011471:Prostatic Neoplasms / Q000139:chemically induced*; D012307:Risk Factors; D013739:Testosterone / Q000009:adverse effects / Q000627:therapeutic use*
D013739:Testosterone