title: Changing relationships of obesity and dyslipidemia in Greek children: 1982-2002.
abstract: BACKGROUND
  The prevalence of childhood overweight and obesity has been increasing rapidly during the past decades in many parts of the world. Less is known with respect to the effects of increasing adiposity on blood lipid profile. The present study was designed to examine the influence of adiposity on secular trends in anthropometric characteristics and plasma lipids of Greek children.
  
  
  METHODS
  A total of 419 and 374 boys with normal body weight and 109 and 246 boys with abnormal body weight (overweight and obese) were randomly recruited in 1982 and 2002, respectively (aged 12.1 +/- 0.1 years). Height, weight, body mass index (BMI, kg/m(2)), Rohrer index (kg/m(3)), plasma total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), TC/HDL-C ratio, and LDL-C/HDL-C ratio were determined.
  
  
  RESULTS
  Temporal changes in weight (positive), BMI (positive), HDL-C (negative), and cholesterol ratios (positive) were greater among overweight and obese vs. normal-weight boys (P < 0.05), while those for height (positive), LDL-C (positive), TG (positive), and TC (no change) were of similar magnitude. The increase in Rohrer index since 1982 failed to reach significance for children with normal body weight (P = 0.077) but did so for overweight and obese subjects (P = 0.027).
  
  
  CONCLUSIONS
  These results indicate that secular increases in measures of fatness and adverse changes in plasma lipids were more pronounced among overweight and obese children than among normal-weight individuals, although qualitatively similar shifts were observed across the entire population.
authors.affiliation: Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Avenue, 17671 Kallithea, Athens, Greece.
authors.forename: Yannis
authors.initials: Y
authors.lastname: Manios
authors.forename: Faidon
authors.initials: F
authors.lastname: Magkos
authors.forename: George
authors.initials: G
authors.lastname: Christakis
authors.forename: Anthony G
authors.initials: AG
authors.lastname: Kafatos
mesh_terms: D050154:Adiposity; D000293:Adolescent; D000886:Anthropometry; D015992:Body Mass Index; D002648:Child; D050171:Dyslipidemias / Q000209:etiology*; D005260:Female; D006115:Greece; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications*