title: Frozen section: Its role in gynaecological oncology.
abstract: The use of frozen section has greatly impacted on the care of the gynaecological oncology patient. Frozen section allows intraoperative evaluation to distinguish benign from malignant tumors in order to tailor the extent of surgery necessary. Frozen section diagnosis in gynaecological oncology is sufficiently sensitive and specific for clinical use. Generally, the false negative rate is low and the false positive rate is negligible. Deferred diagnoses or incompatible frozen section diagnosis is usually due to technical limitations especially for the mucinous ovarian tumors. This review summarises the available literature on the accuracy, limitations and role of frozen section for individual gynaecological tumors.
authors.affiliation: Division of Gynecological Oncology, Nelson R Mandela School of Medicine, Durban, South Africa. moodleym29@ukzn.ac.za
authors.forename: M
authors.initials: M
authors.lastname: Moodley
authors.forename: A
authors.initials: A
authors.lastname: Bramdev
mesh_terms: D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005629:Frozen Sections / Q000379:methods*; D005833:Genital Neoplasms, Female / Q000473:pathology* / Q000601:surgery; D006801:Humans; D009361:Neoplasm Invasiveness / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery