title: First report of leprosy presenting as acute polyarthritis in the setting of type I downgrading lepra reaction.
abstract: Leprosy is a rare cause of acute polyarthritis. We describe the occurrence of oedema of the hands and feet and acute polyarthritis in the setting of type I (downgrading) lepra reaction in an untreated patient with borderline leprosy. This case report further expands the range of articular manifestations that can occur in leprosy.
authors.affiliation: Department of Dermatology, Mubarak Al Kabeer Hospital, Kuwait, Kuwait.
authors.forename: Haneen Adel
authors.initials: HA
authors.lastname: Al-Raqum
authors.forename: S S
authors.initials: SS
authors.lastname: Uppal
authors.forename: Rana Abdul Rahman
authors.initials: RA
authors.lastname: El Abdalghani
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Lasheen
mesh_terms: D000208:Acute Disease; D000328:Adult; D001168:Arthritis / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D015439:Leprosy, Borderline / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D009166:Mycobacterium leprae / Q000276:immunology / Q000302:isolation & purification; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007917:Leprostatic Agents; D003622:Dapsone; D011239:Prednisolone; D002991:Clofazimine