[Predictive factors for progression to cirrhosis in chronic liver diseases].
Chronic liver diseases complications generally occur when fibrosis progresses to cirrhosis. It is recognised that some patients do not progress while others develop significant fibrosis. Factors influencing the fibrosis progression rate are especially studied in chronic hepatitis C. Among many identified factors, the most important are those warranted a medical action such as alcohol consumption, obesity, other metabolic disorders and immunosuppression in case of HIV-HCV coinfection. Especially, in case of chronic liver disease, regular alcohol consumption should be avoided; overweight and metabolic disorders should be controlled. The control of liver damage aetiologies could decrease or even stop fibrosis progression.
Grando-Lemaire
Véronique
V
Service d'hépato-gastroentérologie, hôpital Jean Verdier, Université Paris 13, 93143 Bondy Cedex. veronique.grando@jvr.ap-hop-paris.fr
Kazemi
Farhad
F
Trinchet
Jean-Claude
JC
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000437:Alcoholism / Q000150:complications; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D005544:Forecasting; D015658:HIV Infections / Q000150:complications; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D016867:Immunocompromised Host; D008103:Liver Cirrhosis / Q000209:etiology*; D008107:Liver Diseases / Q000150:complications*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications; D009765:Obesity / Q000150:complications; D012307:Risk Factors; D012737:Sex Factors