title: [Removal of a tracheostomy in ventilator-dependent patients with neuromuscular disease].
abstract: BACKGROUND
  Ventilation via a tracheostomy is effective but very restricting in patients with neuromuscular disease. Return to non-invasive ventilation (NIV) is possible but this is not common practice, partly for want of standardised procedures ensuring a safe transition.
  
  
  METHODS
  A procedure for transfer of ventilation via a tracheostomy to a mask has been developed based on the literature and local experience (feasibility of NIV, absence of laryngo-tracheal lesions, adequate leak compensation, effective cough). It has been tested in three patients with severe but stable neuromuscular disorders (chronic polyneuropathy in two cases and progressive spinal amyotrophy on one).
  
  
  RESULTS
  The three patients were able to be extubated and established on domiciliary ventilation in 6,7 and 10 days, at the end of which all were discharged home. After 4 months in two cases and 6 months in the other no significant complications developed, the respiratory status under NIV was comparable to that previously under tracheostomy and the patients were satisfied with the change.
  
  
  CONCLUSIONS
  The proposed algorithm seems to permit a rapid and safe transition from a tracheostomy to a mask. Large scale studies are needed to verify this concept and subsequently to identify within which group a similar approach may be correctly applied.
authors.affiliation: Service de pneumologie et de réanimation, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique - Hôpitaux de Paris, Paris, France. jesus.gonzalez@psl.ap-hop-paris.fr
authors.forename: J
authors.initials: J
authors.lastname: Gonzalez-Bermejo
authors.forename: M
authors.initials: M
authors.lastname: Godard
authors.forename: A
authors.initials: A
authors.lastname: Duguet
authors.forename: J-P
authors.initials: JP
authors.lastname: Derenne
authors.forename: T
authors.initials: T
authors.lastname: Similowski
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D017214:Laryngeal Masks; D008297:Male; D008875:Middle Aged; D009468:Neuromuscular Diseases / Q000150:complications*; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D014139:Tracheostomy