Possible role of Helicobacter pylori in the etiopathogenesis of chronic otitis media.
OBJECTIVE
To investigate a possible contribution from Helicobacter pylori to the etiopathogenesis of chronic otitis media.


METHODS
Prospective clinical trial.


METHODS
Tympanomastoidectomy, radical mastoidectomy, and modified radical mastoidectomy procedures were performed according to the pathology of ear disease. Biopsy specimens were taken from middle ear, mastoid antrum, and tympanic orifice of eustachian tube. Helicobacter pylori DNA was extracted from these biopsy specimens by using nested polymerase chain reaction.


RESULTS
Helicobacter pylori DNA was detected in 3 (7.9%) of 38 chronic otitis media patients.


CONCLUSIONS
Even though it is possible to detect Helicobacter pylori in middle ear cleft in chronic otitis media, its role in the etiopathogenesis of the issue is controversial.
Kutluhan
Ahmet
A
Department of Otorhinolaryngology, School of Medicine, Yüzüncü Yil University, Van, Turkey. ahkutluhan@hotmail.com
Yurttaş
Veysel
V
Akarca
Ulus Salih
US
Aydn
Ahmet
A
Tuncer
Ilyas
I
Uğraş
Serdar
S
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D002908:Chronic Disease; D004432:Ear, Middle / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008416:Mastoid / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010033:Otitis Media / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D016133:Polymerase Chain Reaction