Inflammatory reaction after sirolimus-eluting stent implant.
Sirolimus-eluting stents (SES) are supposed to attenuate cell proliferation and reduce restenosis rate. Histologic finding from coronary artery after SES implant showed fibrosis and inflammatory infiltrate, revealing a chronic inflammatory reaction. Extension of coronary inflammatory reaction after stenting needs clarification. The long-term consequences are unknown.
Gomes
Walter J
WJ
Escola Paulista de Medicina, São Paulo Hospital, Federal University of São Paulo, São Paulo, Brazil. wjgomes.dcir@epm.br
Giannotti-Filho
Oswaldo
O
Hossne
Nelson A
NA
Catani
Roberto
R
Buffolo
Enio
E
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001026:Coronary Artery Bypass; D023903:Coronary Restenosis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D020123:Sirolimus / Q000627:therapeutic use*; D015607:Stents / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D020123:Sirolimus