Candida albicans endocarditis treatment with caspofungin in an HIV-infected patient--case report and review of literature.
Caspofungin has recently been introduced for the treatment of invasive candidiasis, however, there is limited data on its use in endocarditis. We report a 22-year-old male HIV-infected patient on methadone maintenance therapy that developed right-sided Candida albicans endocarditis. Caspofungin treatment and vegetectomy, followed by fluconazole, was successful in the treatment of our patient. We also review all previous cases of Candida endocarditis treated with caspofungin.
Bacak
Valentina
V
Department of HIV/AIDS, University Hospital for Infectious Diseases, Mirogojska 8, 10000 Zagreb, Croatia.
Biocina
Bojan
B
Starcevic
Boris
B
Gertler
Sarah
S
Begovac
Josip
J
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002176:Candida albicans / Q000187:drug effects*; D002177:Candidiasis / Q000188:drug therapy* / Q000382:microbiology; D000077336:Caspofungin; D054714:Echinocandins; D004696:Endocarditis / Q000188:drug therapy* / Q000382:microbiology; D015658:HIV Infections / Q000150:complications; D006801:Humans; D055666:Lipopeptides; D008297:Male; D010456:Peptides, Cyclic / Q000627:therapeutic use*; D016896:Treatment Outcome
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D000077336:Caspofungin