title: Effect of femoral nutrient artery ligature on radionuclide uptake in rabbits.
abstract: To elucidate the effect of damaging the nutrient artery to a long bone, we used radionuclide imaging to survey the change of femoral blood supply after ligating the nutrient artery in rabbits. The radionuclide uptake of the femoral shaft, upper and lower metaphysis, and epiphysis decreased significantly at 1 hr postoperation (0.66, 0.74, 0.81, respectively, p <0.05), were close to normal on day 4 (0.96, 0.98, 1.02, respectively, p >0.05), slightly exceeded the contralateral level at 9 and 12 days, and returned to normal on day 16. This study shows that ligation of the nutrient artery of a long bone leads to an immediate decrease in the bone blood flow. However, so long as anastomoses among other bone vessels are intact, the recovery rate is speedy, and long-term, serious disorders of the bone blood supply do not ensue.
authors.affiliation: Department of Orthopaedics, Jinling Hospital, Nanjing University Medical School, Nanjing, PR China. zengxiaofeng@msn.com
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Zeng
authors.forename: Weiju
authors.initials: W
authors.lastname: Lu
authors.forename: Jianning
authors.initials: J
authors.lastname: Zhao
authors.forename: Ting
authors.initials: T
authors.lastname: Guo
authors.forename: Bin
authors.initials: B
authors.lastname: Li
mesh_terms: D000818:Animals; D001158:Arteries / Q000502:physiology / Q000601:surgery; D005269:Femur / Q000098:blood supply / Q000000981:diagnostic imaging*; D006614:Hindlimb / Q000000981:diagnostic imaging; D008026:Ligation; D011817:Rabbits; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow; D013669:Technetium Tc 99m Medronate
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate