title: [Swiss scrapie surveillance. II. Epidemiologic aspects of the detection of neurological diseases in sheep and goats].
abstract: Monitoring of transmissible spongiform encephalopathy (TSE) in Swiss sheep and goats is based on the examination of animals from different sources. In this study, frequencies and proportions of the different diagnoses were compared between routinely submitted sheep and goats, notified scrapie suspects as well as fallen stock. Meningitis/ encephalitis cases were significantly more frequent (OR = 2.2) in the scrapie suspect group when compared to the routine submissions. Metabolic-toxic encephalopathy was seen more frequently within the fallen stock. Rare neurological diagnoses were more frequent among scrapie suspects and routine submissions when compared to fallen stock. Listeriosis was diagnosed equally frequent among the scrapie suspects and routine submissions but less frequent in fallen stock. Scrapie prevalence among the fallen stock and the routine submissions was 0 (zero), with 95% certainty that prevalence is < 1%. The examined animals are representative for most of the Swiss regions with considerable sheep and goat production. Continuation of the detailed neuropathological examination of small ruminants from these three groups, substituted by actively testing a sufficiently large sample of fallen stock and possibly also healthy-slaughtered adult sheep and goats for transmissible spongiform encephalopathies would ensure a good surveillance within the small ruminant population.
authors.affiliation: Abteilung klinische Forschung, Dept. klinischeVeterinärmedizin der Universität Bern.
authors.forename: E
authors.initials: E
authors.lastname: Maurer
authors.forename: C
authors.initials: C
authors.lastname: Botteron
authors.forename: A
authors.initials: A
authors.lastname: Zurbriggen
authors.forename: M G
authors.initials: MG
authors.lastname: Doherr
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D005260:Female; D015511:Goat Diseases / Q000175:diagnosis* / Q000453:epidemiology; D006041:Goats; D008297:Male; D009422:Nervous System Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D009460:Neurologic Examination / Q000662:veterinary; D016017:Odds Ratio; D015995:Prevalence; D017096:Prion Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary; D012307:Risk Factors; D012608:Scrapie / Q000175:diagnosis / Q000453:epidemiology; D018571:Sentinel Surveillance / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis* / Q000453:epidemiology; D013557:Switzerland / Q000453:epidemiology