Aminoarenethiolate-copper(I)-catalyzed amination of aryl bromides.
[reaction, structure: see text] Aminoarenethiolate-copper(I) complexes are known to be efficient catalysts for carbon-carbon bond formation. Here, we show the first examples that these thiolate-copper(I) complexes are efficient for carbon-nitrogen bond formation reactions as well. N-Arylation of benzylamine and imidazole with bromobenzene was achieved either in NMP as solvent or under solvent-free conditions in the presence of 2.5 mol % of aminoarenethiolate-copper(I) complex only.
Jerphagnon
Thomas
T
Debye Institute, Organic Chemistry and Catalysis, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
van Klink
Gerard P M
GP
de Vries
Johannes G
JG
van Koten
Gerard
G