The search for glycan function: fucosylation of the TGF-beta1 receptor is required for receptor activation.
Schachter
Harry
H
Program in Structural Biology and Biochemistry, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8. harry@sickkids.ca
D000818:Animals; D005643:Fucose / Q000378:metabolism*; D005647:Fucosyltransferases / Q000235:genetics; D006031:Glycosylation; D006801:Humans; D009154:Mutation; D011134:Polysaccharides / Q000502:physiology*; D018125:Receptors, Transforming Growth Factor beta / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics
D011134:Polysaccharides; D018125:Receptors, Transforming Growth Factor beta; D005643:Fucose; D005647:Fucosyltransferases