[Colorectal cancer. Incidence and risk factors].
Colorectal cancer (CRC) is a common cancer in the more developed Western countries. This paper aims to give a review of the established or suspected and potentially modifiable risk factors for CRC. Increased BMI, physical inactivity, tobacco smoking and high alcohol consumption are strongly implicated factors. The precise dietary patterns associated with increased risk are less clear. Use of NSAIDs as well as postmenopausal hormones seems to be associated with a substantially reduced risk of CRC. Altogether, the evidence indicates that primary prevention of CRC is feasible.
Nørgaard
Mette
M
Arhus Universitetshospital, Aalborg Sygehus, Klinisk Epidemiologisk Afdeling, Aalborg. uxmeno@aas.nja.dk
Iversen
Lene Hjerrild
LH
Sørensen
Henrik Toft
HT
D018256:Adenomatous Polyps / Q000150:complications; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D003718:Denmark / Q000453:epidemiology; D005247:Feeding Behavior; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000150:complications; D008297:Male; D012307:Risk Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal