[Regulation of prostaglandin E molecular network in mammalian reproduction].
Prostaglandin E molecular network includes cyclooxygenase, phospholipase A2, prostaglandin E, prostaglandin E receptors, and prostaglandin E synthase. Recently, it was found that PGE2 receptors localized not only on the cell membrane but also on the envelope of nucleus. They are different in the signaling pathways and in regulation mechanism between nuclear receptors and membrane receptors. They compose a delicate network, which plays important roles in mammalian reproduction, especially in most processes of female reproduction.
Luan
Li-Ming
LM
College of Life Sciences, Northeast Agricultural University, Harbin 150030.
Chen
Ying
Y
Yang
Zeng-Ming
ZM
D000818:Animals; D054513:Group IV Phospholipases A2; D006801:Humans; D019746:Intramolecular Oxidoreductases / Q000502:physiology*; D010741:Phospholipases A / Q000502:physiology; D054467:Phospholipases A2; D000071876:Prostaglandin-E Synthases; D011451:Prostaglandin-Endoperoxide Synthases / Q000502:physiology; D011458:Prostaglandins E / Q000502:physiology*; D018078:Receptors, Prostaglandin E / Q000502:physiology*; D012098:Reproduction / Q000502:physiology*; D015398:Signal Transduction
D011458:Prostaglandins E; D018078:Receptors, Prostaglandin E; D011451:Prostaglandin-Endoperoxide Synthases; D010741:Phospholipases A; D054513:Group IV Phospholipases A2; D054467:Phospholipases A2; D019746:Intramolecular Oxidoreductases; D000071876:Prostaglandin-E Synthases