title: Chromatographic separation of (-)-ephedrine and (+)-pseudoephedrine in the traditional Chinese medicinal preparation Jiketing granule.
abstract: (-)-Ephedrine (EP) and (+)-Pseudoephedrine (PEP) in Jiketing granule were separated by TLC, RP-HPLC, GC, HPLC-MS, and the chromatographic phenomenon was interpreted by the topological indices. The observed chromatographic separations of investigated components were compared. This comparison indicated that simply methods as C18 RP-HPLC and GC are the more effective techniques, and more suitable than others for this preparation, for the separation of two alkaloids.
authors.affiliation: Analytic Center, China Pharmaceutical University, Nanjing, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Luhua
authors.forename: Yan
authors.initials: Y
authors.lastname: Fang
authors.forename: Yang
authors.initials: Y
authors.lastname: Lili
authors.forename: Xiang
authors.initials: X
authors.lastname: Bingren
mesh_terms: D000697:Central Nervous System Stimulants / Q000302:isolation & purification*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004809:Ephedrine / Q000302:isolation & purification*; D013058:Mass Spectrometry; D012044:Regression Analysis; D015203:Reproducibility of Results; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000697:Central Nervous System Stimulants; D004365:Drugs, Chinese Herbal; D004809:Ephedrine