Iron-regulatory protein hepcidin is increased in female athletes after a marathon.
The propose of this study was to determine the influence of marathon race on hepcidin excretion in female athletes (age 26-45 years). Urine samples were taken before, immediately after, 1 and 3 days after the race. In the average, hepcidin transiently increased at day 1 from 32 to 85 ng/mg creatinine. We propose that the frequently observed iron deficiency of females runners is caused by elevated hepcidin levels.
Roecker
L
L
Labor 28, Mecklenburgische Str. 28, 14193, Berlin, Germany. lroecker@zedat.fu-berlin.de
Meier-Buttermilch
R
R
Brechtel
L
L
Nemeth
E
E
Ganz
T
T
D000328:Adult; D023181:Antimicrobial Cationic Peptides / Q000652:urine*; D005260:Female; D064451:Hepcidins; D006801:Humans; D000090463:Iron Deficiencies; D010807:Physical Endurance / Q000502:physiology*; D012420:Running / Q000502:physiology*
D023181:Antimicrobial Cationic Peptides; C578702:HAMP protein, human; D064451:Hepcidins