title: 3-D numerical simulation of blood flow through models of the human aorta.
abstract: A Spiral Computerized Tomography (CT) scan of the aorta were obtained from a single subject and three model variations were examined. Computational fluid dynamics modeling of all three models showed variations in the velocity contours along the aortic arch with differences in the boundary layer growth and recirculation regions. Further down-stream, all three models showed very similar velocity profiles during maximum velocity with differences occurring in the decelerating part of the pulse. Flow patterns obtained from transient 3-D computational fluid dynamics are influenced by different reconstruction methods and the pulsatility of the flow. Caution is required when analyzing models based on CT scans.
authors.affiliation: Centre for Applied Biomedical Engineering Research, Dept. Mechanical & Aeronautical Eng. and Material and Surface Science Institute, University of Limerick, Castletroy, Limerick, Ireland.
authors.forename: L
authors.initials: L
authors.lastname: Morris
authors.forename: P
authors.initials: P
authors.lastname: Delassus
authors.forename: A
authors.initials: A
authors.lastname: Callanan
authors.forename: M
authors.initials: M
authors.lastname: Walsh
authors.forename: F
authors.initials: F
authors.lastname: Wallis
authors.forename: P
authors.initials: P
authors.lastname: Grace
authors.forename: T
authors.initials: T
authors.lastname: McGloughlin
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging* / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D003198:Computer Simulation; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D033081:Shear Strength