title: "Occult" osteoporotic vertebral fractures: vertebral body fractures without radiologic collapse.
abstract: METHODS
  Retrospective observational study.
  
  
  OBJECTIVE
  We report our experience with patients who presented with osteoporotic vertebral fractures with no visible deformation of vertebral body.
  
  
  BACKGROUND
  The diagnosis of osteoporotic vertebral fractures largely relies on the observation of vertebral deformations on plain radiographs, termed vertebral collapses. There are no data on the characteristics, or indeed of the reality, of osteoporotic vertebral fractures with no significant deformation of the vertebral body.
  
  
  METHODS
  We retrospectively analyzed cases that presented with acute back pain with no initial deformation of the vertebral body on plain radiographs, and later proved to be fresh osteoporotic vertebral body fractures. All cases met each of the following criteria: 1) The incriminated vertebra appeared normal on initial radiographs (Genant's Grade 0 deformation). 2) The diagnosis of fresh vertebral body fracture was confirmed by MRI. 3) The diagnosis of osteoporosis was made by the combination of established osteoporosis, ruling out of underlying disease, and follow-up.
  
  
  RESULTS
  We observed 21 fractures in 16 patients (11 female/5 male; mean age, 72 years). Most of these fractures affected the lumbar spine (14 of 21 occurred at L2-L5). Osteoporosis was known beforehand in 9 patients and newly diagnosed in 7 patients. At follow-up, radiographs were obtained for 19 of 21 fractures: in 15 cases, the vertebral fracture developed a vertebral collapse (Genant's Grade > or = 0.5) in a mean of 12.5 weeks (range, 4-24 weeks); in the 4 remaining cases, the vertebra remained normal. All cases had a clinically favorable outcome.
  
  
  CONCLUSIONS
  Osteoporotic vertebral fractures with no sign of vertebral collapse on initial radiographs do indeed exist. They are analogous to occult stress fractures well known in other skeletal sites. They must not be misdiagnosed as malignant lesions.
authors.affiliation: Department of Rheumatology, Hôpital la Conception, Baille, France.
authors.forename: Thao
authors.initials: T
authors.lastname: Pham
authors.forename: Johanna
authors.initials: J
authors.lastname: Azulay-Parrado
authors.forename: Pierre
authors.initials: P
authors.lastname: Champsaur
authors.forename: Christophe
authors.initials: C
authors.lastname: Chagnaud
authors.forename: Virginie
authors.initials: V
authors.lastname: Legré
authors.forename: Pierre
authors.initials: P
authors.lastname: Lafforgue
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001416:Back Pain / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005596:Fractures, Closed / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D013131:Spine / Q000473:pathology