[Serum lipids concentration and colorectal cancer].
The authors present current concepts concerning the relationships between plasma lipid concentration and incidence of colorectal cancer. Pharmacological reduction of cholesterolaemia may decrease mortality of cardiovascular causes' simultaneously increasing mortality of non-vascular causes. Discussion concerns the idea of preclinical action of the neoplasm on lowering cholesterol level as well as hypothesis of increased biliary secretion of cholesterol metabolites, that may have cancerogenic effect. Cholesterol plasma concentration and its impact on aetiopathogenesis of colorectal cancer still need to be investigated.
Muszyński
Jacek
J
Katedra i Klinika Gastroenterologii i Chorób Przemiany Materii Akademii Medycznej, Warszawie. muszkaj@amwaw.edu.pl
Ehrmann-Jóśko
Agnieszka
A
D000924:Anticholesteremic Agents / Q000627:therapeutic use; D002784:Cholesterol / Q000097:blood; D015179:Colorectal Neoplasms / Q000097:blood* / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008055:Lipids / Q000097:blood*
D000924:Anticholesteremic Agents; D008055:Lipids; D002784:Cholesterol