title: Gadolinium-enhanced computed tomographic angiography: current status.
abstract: This article reviews the research to date, as well as our clinical experience from two institutions, on gadolinium-enhanced computed tomographic angiography (gCTA) for imaging the body. gCTA may be an appropriate examination for the small percentage of patients who would benefit from noninvasive vascular imaging, but who have contraindications to both iodinated contrast and magnetic resonance imaging. gCTA is more expensive than CTA with iodinated contrast, due to the dose of gadolinium administered, and gCTA has limitations compared with CTA with iodinated contrast, in that parenchymal organs are not optimally enhanced at doses of 0.5 mmol/kg or lower. However, in our experience, gCTA has been a very useful problem-solving examination in carefully selected patients. With the advent of 16-64 detector CT, in combination with bolus tracking, we believe that the overall dose of gadolinium needed for diagnostic CTA examinations, while relatively high, can be safely administered.
authors.affiliation: Department of Radiology, Winthrop-University Hospital, Mineola, NY 11501, USA.
authors.forename: Alex
authors.initials: A
authors.lastname: Rosioreanu
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Alberico
authors.forename: Alan
authors.initials: A
authors.lastname: Litwin
authors.forename: Man
authors.initials: M
authors.lastname: Hon
authors.forename: Zachary D
authors.initials: ZD
authors.lastname: Grossman
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Katz
mesh_terms: D000792:Angiography / Q000379:methods*; D000818:Animals; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA