Propynyl groups in duplex, hairpin and triplex DNA: 7-deazapurines and 9-deazapurines.
Oligonucleotides containing 7-deazapurines or 9-deazapurines with propynyl groups at the 7- or 9-position were prepared. The stabilizing effect of the propynyl group was studied on DNA duplexes, hairpins and triplexes.
Seela
Frank
F
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Germany.
Shaikh
Khalil I
KI
Budow
Simone
S
Jawalekar
Anup M
AM
D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D008956:Models, Chemical; D008967:Molecular Biology / Q000379:methods; D008969:Molecular Sequence Data; D009692:Nucleic Acid Heteroduplexes / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry; D016376:Oligonucleotides, Antisense / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry; D011687:Purines / Q000737:chemistry* / Q000494:pharmacology; D013696:Temperature; D013816:Thermodynamics
D009692:Nucleic Acid Heteroduplexes; D009841:Oligonucleotides; D016376:Oligonucleotides, Antisense; D009943:Organophosphorus Compounds; D011687:Purines; D004247:DNA