title: [Myosin light chains of skeletal and cardiac muscles of ground squirrel Citillus undulatus in different periods of hibernation].
abstract: The isoform composition of myosin light chains and the extent of their phosphorylation in skeletal and cardiac muscles of ground squirrel Citellus undulatus in different periods of hibernation were studied. Regulatory myosin light chains of skeletal muscles of hibernating ground squirrels were completely dephosphorylated, while 25% of these light chains in active animals were phosphorylated. During hibernation, a shift of isoform composition of essential and regulatory skeletal muscle myosin light chains toward slower isoforms was observed, which is evidenced by the data obtained on m. psoas and on the totality of all skeletal muscles. In the atrial myocardium of hibernating ground squirrels, ventricular myosin light chains 1 (up to 60%) were registered. In contrast, during arousal of ground squirrels, in ventricular myocardium the appearance of atrial myosin light chains 1 (up to 30%) was revealed. A possible role of posttranslation changes in myosin light chains and their isoform shifts in the hibernation scenario is discussed.
authors.forename: O V
authors.initials: OV
authors.lastname: Zuĭkova
authors.forename: D A
authors.initials: DA
authors.lastname: Osipova
authors.forename: I M
authors.initials: IM
authors.lastname: Vikhliantsev
authors.forename: S L
authors.initials: SL
authors.lastname: Malyshev
authors.forename: S N
authors.initials: SN
authors.lastname: Udal'tsov
authors.forename: Z A
authors.initials: ZA
authors.lastname: Podlubnaia
mesh_terms: D000818:Animals; D006325:Heart Atria / Q000378:metabolism; D006605:Hibernation / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D018994:Myosin Light Chains / Q000378:metabolism*; D010766:Phosphorylation; D020033:Protein Isoforms / Q000378:metabolism; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D012589:Sciuridae / Q000502:physiology*
chemical_list: D018994:Myosin Light Chains; D020033:Protein Isoforms