Landouzy septicemia (sepsis tuberculosa acutissima) due to Mycobacterium microti in an immunocompetent man.
Even in developed countries, tuberculosis still contributes significantly to morbidity and mortality. The most frequent causative agent is Mycobacterium tuberculosis, while infections due to other mycobacterial species are usually associated with immunocompromised patients. In the following, we describe the case of a previously healthy man who underwent laparotomy for suspected adrenal carcinoma. Peritoneal "cancerous nodules" turned out to be tuberculous granulomas. After surgery the patient developed a protracted septic shock and died 6 days after surgery. Isolation and identification of the causative agent yielded Mycobacterium microti, an uncommon species of the M. tuberculosis complex. No other pathogen could be isolated during the clinical course, which finally led to the diagnosis of Landouzy septicemia (sepsis tuberculosa acutissima).
Geiss
H K
HK
Section Infectiology, Institute of Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany. heiko.geiss@med.uni-heidelberg.de
Feldhues
Rita
R
Niemann
S
S
Nolte
O
O
Rieker
R
R
D000368:Aged; D016470:Bacteremia / Q000382:microbiology*; D017809:Fatal Outcome; D006099:Granuloma / Q000473:pathology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D009161:Mycobacterium / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000150:complications* / Q000382:microbiology* / Q000473:pathology