title: A new fungicide produced by a Streptomyces sp. GAAS7310.
abstract: Directed bioassay guided fraction led to a new macrodiolide antimycin A(17) (1), isolated from a Streptomyces sp. GAAS7310, which showed significant antimicrobial activity against eleven fungal species, including Curvularia lunata (Wakker) Boed, Rhizopus nigrtcans Ehrb and Colletotrichum nigrum EL. et Halst. The structure was unambiguously established by interpretation of 1D and 2D NMR data and comparison with the known antimycin A(1a).
authors.affiliation: Department of Chemistry, Hainan Normal University, Haikou 571158, People's Republic of China.
authors.forename: Guangying
authors.initials: G
authors.lastname: Chen
authors.forename: Birun
authors.initials: B
authors.lastname: Lin
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Lin
authors.forename: Fengchun
authors.initials: F
authors.lastname: Xie
authors.forename: Wen
authors.initials: W
authors.lastname: Lu
authors.forename: Wang-Fun
authors.initials: WF
authors.lastname: Fong
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D000968:Antimycin A / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D020231:Colletotrichum / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D012233:Rhizopus / Q000187:drug effects; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D000968:Antimycin A