A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones.
5-Pyrrolidin-2-yltetrazole performs as an improved catalyst for the asymmetric addition of a range of nitroalkanes to cyclic and acyclic enones, with good to excellent enantioselectivity.
Mitchell
Claire E T
CE
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Brenner
Stacey E
SE
Ley
Steven V
SV