title: Management of interstitial pregnancy using selective uterine artery embolization.
abstract: BACKGROUND
  Interstitial pregnancy is a rare and dangerous form of ectopic pregnancy which is treated by surgery, medical treatment, or both. Management options are not standardized. Currently, conservative nonsurgical treatment seems to be an alternative method in case of interstitial pregnancy.
  
  
  METHODS
  A right interstitial pregnancy was diagnosed in a 28-year-old woman. She was successfully treated by 2 courses of systemic methotrexate (1 mg/kg) 24 hours apart followed by selective uterine artery embolization. The postembolization course was uneventful, and no rupture occurred. Ten weeks after embolization, human chorionic gonadotropin level was negative.
  
  
  CONCLUSIONS
  Uterine embolization associated with methotrexate can be used successfully in treating selected cases of early interstitial pregnancy. We hypothesize that this procedure combined with methotrexate could reduce hemorrhagic risk.
authors.affiliation: Service de Gynécologie, Hôpital Jeanne de Flandre, Universitaire de Lille, France. p-deruelle@chru-lille.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Deruelle
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Lucot
authors.forename: Christophe
authors.initials: C
authors.lastname: Lions
authors.forename: Yann
authors.initials: Y
authors.lastname: Robert
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000328:Adult; D006063:Chorionic Gonadotropin / Q000032:analysis; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy* / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome; D014599:Uterus / Q000098:blood supply* / Q000473:pathology
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D006063:Chorionic Gonadotropin; D008727:Methotrexate