title: Acute onset of polymyalgia rheumatica in pregnancy.
abstract: BACKGROUND
  Polymyalgia rheumatica is uncommon in young women and remains a diagnostic challenge for pregnant women.
  
  
  METHODS
  A 28-year-old pregnant woman developed polymyalgia rheumatica in the third trimester. Laboratory investigations revealed elevated erythrocyte sedimentation rate and C-reactive protein levels with normal muscle enzyme levels and seronegativity for rheumatoid factor. Although her symptoms deteriorated as pregnancy progressed, she drastically improved by treatment with prednisone. She underwent cesarean delivery at 39 weeks. She was relapse-free of polymyalgia rheumatica after discontinuation of prednisone on the 50th postoperative day.
  
  
  CONCLUSIONS
  The diagnosis of polymyalgia rheumatica is important to properly manage pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, and Department of Obstetrics and Gynecology, Akashi Medical Center, Akashi, Japan. hiro.sasaki@hosp.kobe-u.ac.jp
authors.forename: Hiroko
authors.initials: H
authors.lastname: Sasaki
authors.forename: Motoo
authors.initials: M
authors.lastname: Washio
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ohara
authors.forename: Takeshi
authors.initials: T
authors.lastname: Maruo
mesh_terms: D000208:Acute Disease; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011111:Polymyalgia Rheumatica / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000188:drug therapy; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D012008:Recurrence; D012307:Risk Factors
chemical_list: D000893:Anti-Inflammatory Agents; D002097:C-Reactive Protein; D011241:Prednisone