title: [Clinical research on combined therapy of diane-35 with modified yougui pill on polycystic ovarian syndrome].
abstract: OBJECTIVE
  To investigate the clinical efficacy of integrative traditional Chinese and Western medicine on polycystic ovarian syndrome (PCOC).
  
  
  METHODS
  Sixty-three patients with polycystic ovarian syndrome were randomly allocated into 2 groups, 31 patients orally administered with diane-35 in the Western medicine group (WMG) and 32 patients treated with conventional controlled medicine plus modified Yougui Pill in the integrative medicine group (IMG). Changes of relevant hormones and clinical syndromes in patients were detected before treatment, after 3 cyclic treatment and at the 6th cycle after treatment.
  
  
  RESULTS
  The levels of relevant hormones and the indexes of B-ultrasonic were obviously improved after treatment in the two groups. But 6 cycles after treatment, these changes restored to the baseline as those before treatment in WMG, while maintained in IMG (P < 0.01). What's more, the normalization of menstruation, ovulation and pregnancy rate in IMG were significantly higher than those in WMG (P < 0.01).
  
  
  CONCLUSIONS
  Diane-35 combined with modified yougui pill in treating polycystic ovarian syndrome not only shows marked short-term effect, but could consolidate the curative effect.
authors.affiliation: Fujian Provincial People's Hospital, Fuzhou. fjcjy-01@163.com
authors.forename: Li-sheng
authors.initials: LS
authors.lastname: Chen
authors.forename: Jin-tang
authors.initials: JT
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use; D017373:Cyproterone Acetate / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004997:Ethinyl Estradiol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008517:Phytotherapy; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy*; D013607:Tablets
chemical_list: D000726:Androgen Antagonists; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D013607:Tablets; D004997:Ethinyl Estradiol; D017373:Cyproterone Acetate; C032640:Cyproterone acetate, ethinyl estradiol drug combination