[Observation on effect of compound danshen droplet-pill combined with trimetazidine in treating senile unstable angina pectoris].
OBJECTIVE
To investigate the effect of compound Danshen Droplet-pill (DS) combined with trimetazidine (TMZ) in treating senile unstable angina pectoris (SUAP).


METHODS
One hundred and twenty patients with SUAP were eaually and randomly divided into 2 groups, the treated group and the control group. Changes of angina, occurrence of arrhythmia, myocardial infarction and sudden death, myocardial ischemia in ECG and partial indexes of heart function were observed.


RESULTS
The total effective rate in the treated group was 78.3%, while that in the control group was 53.3%, comparison of the two groups showed significant difference (P < 0.05). The incidence rate of arrhythmia in the two groups was 18.2% and 30.0% respectively and that of acute myocardial infarction and sudden death was 0 and 5.0% respectively, also showed significant difference between them (P < 0.05). Condition of myocardial ischemia revealed in ECG and partial indexes of heart function in the treated group were all improved to certain extent. Conclusion DS combined with TMZ is superior in treating SUAP.
Qiu
Zhong-xia
ZX
Clinical College of China Medical University, Shenyang. qiuzhongxia116600@vip.sina.com
Ma
He-jun
HJ
Wang
Di-fei
DF
D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010618:Phenanthrolines / Q000627:therapeutic use; D008517:Phytotherapy; D027561:Salvia miltiorrhiza; D014292:Trimetazidine / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use
D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; D014665:Vasodilator Agents; C028972:dan-shen root extract; D014292:Trimetazidine