Preparation and characterization of nanoaggregates of poly(ethylene oxide)-b-polymethacrylate and poly-L-lysine.
Poly(ethylene oxide)-b-polymethacrylate (PEO-b-PMA), one of the double-hydrophilic block copolymers, has proved to the form nanoaggregates with poly-L-lysine (PLS). This was confirmed by turbidimetry, zeta-potential measurements, and dynamic light scattering. The nanoaggregate formation is induced by electrostatic charge neutralization of the PMA block with PLS. The properties of the aggregates are affected by PLS concentration as well PEO-b-PMA concentration. The aggregates have potential applications in biomedical science.
Li
Yuan
Y
Department of Chemistry, Faculty of Science and Engineering, Saga University, 1 Honjo-machi, Saga 840-8502, Japan.
Ding
Lu-Jun
LJ
Nakamura
Hiroyuki
H
Nakashima
Kenichi
K
D005027:Ethylene Oxide / Q000737:chemistry*; D036103:Nanotechnology; D011095:Polyethylenes / Q000737:chemistry*; D011107:Polylysine / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D011109:Polymethacrylic Acids / Q000737:chemistry*
D011095:Polyethylenes; D011108:Polymers; D011109:Polymethacrylic Acids; C030613:polymethacrylic acid; D011107:Polylysine; D005027:Ethylene Oxide