title: Psychopathology in children: improvement of quality of life without psychiatric symptom reduction?
abstract: OBJECTIVE
  The aim of this study was to assess the association between change in psychopathology and Quality of Life (QoL) across time in children with high levels of psychopathology.
  
  
  METHODS
  A referred sample of 126 seven- to 19-year-olds was studied across a 1-year follow-up period. Information concerning QoL and psychopathology was obtained from parents.
  
  
  RESULTS
  Overall, 38.1% of children showed neither psychiatric symptom reduction nor QoL improvement, 33.3% of children showed both a clinically significant psychiatric symptom reduction and QoL improvement, and 28.6% of children showed either psychiatric symptom reduction or QoL improvement. In 11.1% of all children, QoL improved, while the level of psychopathology remained high. Age, gender, or psychiatric diagnosis did not predict a poor outcome of persistently high psychopathology scores and poor QoL.
  
  
  CONCLUSIONS
  QoL in children with psychiatric problems may be improved by reducing psychiatric symptoms in a number of children, but it is also possible to improve QoL without psychiatric symptom reduction. This implicates that QoL should become an important aim and treatment outcome measure of psychiatric treatment programs, especially since psychopathology tends to persist.
authors.affiliation: Erasmus-MC, University Medical Center Rotterdam, Sophia Children's Hospital, Department of Child and Adolescent Psychiatry, The Netherlands. d.bastiaansen@erasmusmc.nl
authors.forename: Dennis
authors.initials: D
authors.lastname: Bastiaansen
authors.forename: Hans M
authors.initials: HM
authors.lastname: Koot
authors.forename: Robert F
authors.initials: RF
authors.lastname: Ferdinand
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications* / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D012737:Sex Factors; D016896:Treatment Outcome