Combination of poly(L-lysine)-graft-dextran copolymer and 2'-O,4'-C-methylene bridged nucleic acid (2',4'-BNA) modification synergistically stabilizes pyrimidine motif triplex at neutral pH.
Torigoe
Hidetaka
H
Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
Katayama
Takuma
T
Obika
Satoshi
S
Maruyama
Atushi
A
Imanishi
Takeshi
T
D020816:Amino Acid Motifs; D004247:DNA / Q000737:chemistry; D003911:Dextrans / Q000737:chemistry*; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008239:Lysine / Q000737:chemistry; D008956:Models, Chemical; D008967:Molecular Biology / Q000295:instrumentation / Q000379:methods*; D009696:Nucleic Acids / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry; D011107:Polylysine / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D011743:Pyrimidines / Q000737:chemistry*; D013696:Temperature; D014466:Ultraviolet Rays
D003911:Dextrans; D009696:Nucleic Acids; D009841:Oligonucleotides; D011108:Polymers; D011743:Pyrimidines; C051802:triplex DNA; D011107:Polylysine; D004247:DNA; D008239:Lysine; C030986:pyrimidine