Systemic sarcoidosis: the "leopard-man" sign.
Systemic sarcoidosis is often diagnosed late. A 37 year-old man from the Antilles was admitted for evaluation of arthralgia, subcutaneous and cutaneous nodules, multiple enlarged lymph nodes, and an epididymal lump. He had been given a diagnosis of epididymal and nodal tuberculosis but had not responded to antitubercular agents. Gallium-67 scintigraphy showed multiple hot spots in the soft tissues, skin, muscles, mediastinum, and lachrymal glands, producing a diffuse dappled pattern. Magnetic resonance imaging of the thighs confirmed the muscular and subcutaneous involvement. Systemic sarcoidosis was diagnosed. Prednisone therapy was promptly effective. We suggest the term "dappled-body sign" or "leopard-man sign" to designate the heretofore undescribed scintigraphic pattern in our patient.
Fayad
Fouad
F
Rheumatology Federation, Viggo Petersen Center, Lariboisière Teaching Hospital, Paris (AP-HP), France.
Duet
Michèle
M
Orcel
Philippe
P
Lioté
Frédéric
F
D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D005710:Gallium Radioisotopes; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D011877:Radionuclide Imaging; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy; D012867:Skin / Q000000981:diagnostic imaging / Q000473:pathology
D005710:Gallium Radioisotopes; D005938:Glucocorticoids; D011241:Prednisone