Microfluidic technologies in drug discovery.
Microfluidic systems are increasingly used as tools in various stages of the drug discovery process. Microscale systems offer several obvious advantages, such as low sample consumption and significantly reduced analysis or experiment time. These technologies raise the possibility of massive parallelization and concomitant reduction in cost per acquired data point. In addition, fluids in confined spaces display unique behaviors that can be used to acquire information not accessible using macroscopic systems. This article will focus on the implementation of microfluidic systems and technologies in the process of drug discovery.
Pihl
Johan
J
Cellectricon AB, Fabriksgatan 7, SE-412 50 Gothenburg, Sweden. johan.pihl@cellectricon.com
Karlsson
Mattias
M
Chiu
Daniel T
DT
D002626:Chemistry, Pharmaceutical / Q000295:instrumentation / Q000379:methods / Q000639:trends; D044085:Microfluidics / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods / Q000639:trends