Meditation experience is associated with increased cortical thickness.
Previous research indicates that long-term meditation practice is associated with altered resting electroencephalogram patterns, suggestive of long lasting changes in brain activity. We hypothesized that meditation practice might also be associated with changes in the brain's physical structure. Magnetic resonance imaging was used to assess cortical thickness in 20 participants with extensive Insight meditation experience, which involves focused attention to internal experiences. Brain regions associated with attention, interoception and sensory processing were thicker in meditation participants than matched controls, including the prefrontal cortex and right anterior insula. Between-group differences in prefrontal cortical thickness were most pronounced in older participants, suggesting that meditation might offset age-related cortical thinning. Finally, the thickness of two regions correlated with meditation experience. These data provide the first structural evidence for experience-dependent cortical plasticity associated with meditation practice.
Lazar
Sara W
SW
Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, Boston, Massachusetts, USA. lazar@nmr.mgh.harvard.edu
Kerr
Catherine E
CE
Wasserman
Rachel H
RH
Gray
Jeremy R
JR
Greve
Douglas N
DN
Treadway
Michael T
MT
McGarvey
Metta
M
Quinn
Brian T
BT
Dusek
Jeffery A
JA
Benson
Herbert
H
Rauch
Scott L
SL
Moore
Christopher I
CI
Fischl
Bruce
B
D000328:Adult; D001288:Attention; D003071:Cognition; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019122:Meditation; D009473:Neuronal Plasticity; D017397:Prefrontal Cortex / Q000033:anatomy & histology*