The Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms influence the late inflammatory response in human endotoxemia.
Marsik
Claudia
C
Department of Clinical Pharmacology, Medical University of Vienna, Austria.
Jilma
Bernd
B
Joukhadar
Christian
C
Mannhalter
Christine
C
Wagner
Oswald
O
Endler
Georg
G
D019943:Amino Acid Substitution; D015415:Biomarkers; D002097:C-Reactive Protein / Q000032:analysis; D019446:Endotoxemia / Q000378:metabolism / Q000503:physiopathology*; D004926:Escherichia coli; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007375:Interleukin-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008070:Lipopolysaccharides / Q000494:pharmacology; D008297:Male; D009154:Mutation; D011110:Polymorphism, Genetic; D051197:Toll-Like Receptor 4 / Q000235:genetics*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D007375:Interleukin-1; D015850:Interleukin-6; D008070:Lipopolysaccharides; D051197:Toll-Like Receptor 4; D014409:Tumor Necrosis Factor-alpha; C036309:fibrin fragment D; D002097:C-Reactive Protein