Measurement of neutrophil membrane CD64 and HLA-Dr in a patient with abdominal sepsis.
A patient with abdominal sepsis, had both intra and extracellular bacteria in a blood smear, and high levels of neutrophil membrane CD64 and HLA-Dr. Intracellular bacteria are only observed in the terminal phase of a sepsis. Our patient recovered, suggesting that a high expression of neutrophil CD64 is indicative for a good prognosis.
van der Meer
Wim
W
Department of Clinical Chemistry, Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. w.vandermeer@akc.umcn.nl
Stephen Scott
Colin
C
Verlaat
Carin
C
Gunnewiek
Jacqueline Klein
JK
Warris
Adilia
A
D000005:Abdomen; D016470:Bacteremia / Q000382:microbiology; D002675:Child, Preschool; D021902:Enterobacter aerogenes / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D013293:Enterococcus faecalis / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology; D006684:HLA-DR Antigens / Q000378:metabolism*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology; D017452:Receptors, IgG / Q000378:metabolism*; D018805:Sepsis / Q000209:etiology* / Q000276:immunology*
D006684:HLA-DR Antigens; D017452:Receptors, IgG