title: Fluoride concentrations in enamel and dentin of primary teeth after pre- and postnatal fluoride exposure.
abstract: The aim of this study was to determine any existing difference in the amount of fluoride incorporated in the surface, body enamel and dentin of two groups of deciduous teeth, either exposed to pre- and postnatal fluoride supplements or to postnatal fluoride only. One hundred and eighty five subjects with intact deciduous incisors were selected from a randomized, double blind study of the caries preventive efficacy of prenatal fluoride (F) supplementation. Surface and body enamel samples were obtained by the acid etch biopsy technique. Dentin microsamples were obtained by drilling to a depth of 100 microm using the microdrill biopsy technique. It was concluded that fluoride exposure during the prenatal period offered no additional measurable fluoride uptake by dental tissues other than that attributable to postnatal fluoride alone.
authors.affiliation: Department of Clinical Dentistry, Universidade Federal do Ceará, Fortaleza, Brazil. cfontele@ufc.br
authors.forename: C
authors.initials: C
authors.lastname: Sá Roriz Fonteles
authors.forename: D T
authors.initials: DT
authors.lastname: Zero
authors.forename: M E
authors.initials: ME
authors.lastname: Moss
authors.forename: J
authors.initials: J
authors.lastname: Fu
mesh_terms: D002327:Cariostatic Agents / Q000032:analysis*; D002675:Child, Preschool; D003743:Dental Enamel / Q000737:chemistry*; D003804:Dentin / Q000737:chemistry*; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D039401:Prenatal Nutritional Physiological Phenomena; D014094:Tooth, Deciduous / Q000737:chemistry
chemical_list: D002327:Cariostatic Agents; D005459:Fluorides