title: Electrolyzed hydrogen-saturated water for drinking use elicits an antioxidative effect: a feeding test with rats.
abstract: A new type of electrolyzed hydrogen-saturated (EHS) water was produced using a water-electrolyzing device equipped with a special cation exchanger. Use of the EHS water for drinking in a feeding test with rats elicited an antioxidative effect. After intraperitoneal injection of 2,2-azobis-amidinopropane dihydrochloride, urinary secretion of 8-hydroxydeoxyguanosine and hepatic formation of peroxidized lipid were significantly lessened in rats which had received the EHS water for one week. These results suggest the possibility that this drinking water shows an effect in reduction of oxidative stress in the body.
authors.affiliation: MiZ Co., Ltd., Fujisawa-shi, Kanagawa, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yanagihara
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Arai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Miyamae
authors.forename: Bunpei
authors.initials: B
authors.lastname: Sato
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Shudo
authors.forename: Masaharu
authors.initials: M
authors.lastname: Yamada
authors.forename: Masahide
authors.initials: M
authors.lastname: Aoyama
mesh_terms: D000080242:8-Hydroxy-2'-Deoxyguanosine; D000578:Amidines / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D003849:Deoxyguanosine / Q000031:analogs & derivatives / Q000652:urine; D004563:Electrochemistry; D006859:Hydrogen / Q000008:administration & dosage / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D016877:Oxidants / Q000008:administration & dosage / Q000494:pharmacology; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects; D051381:Rats; D014867:Water / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000578:Amidines; D000975:Antioxidants; D016877:Oxidants; D014867:Water; C046728:2,2'-azobis(2-amidinopropane); D006859:Hydrogen; D000080242:8-Hydroxy-2'-Deoxyguanosine; D003849:Deoxyguanosine