Practical cancer genetics, genomics and proteomics.
Functional genomics is the science that defines the function of newly identified genes and translates this knowledge into related health and disease. Functional genomics is complex, involving multiple scientific disciplines including computational biology, genetics, physiology, structural biology, and molecular and cell biology. Due to its inherent complexity, the National Institutes of Health (NIH) has termed functional genomics "the science of collaboration." This paper will review microarray gene expression analysis, proteomics, and the impact of molecular medical genetics on medical care.
Gruber
Michael P
MP
University of Colorado Health Sciences Center, USA.
Geraci
Mark W
MW
D015870:Gene Expression; D018390:Gene Targeting / Q000639:trends; D023281:Genomics / Q000639:trends*; D006801:Humans; D008495:Medical Oncology / Q000639:trends*; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D040901:Proteomics; D014481:United States