[A case of Mycobacterium intracellulare lung disease that was detected by health examination and was successfully cured by chemotherapy--including discussions on the diagnostic criteria of the disease].
A case was 56 years old woman, and she did not have any subjective symptom. She received multiphasic health screening, and abnormal shadow was detected on her chest radiograph. Chest radiography revealed infiltrations in the middle lobe. Computed tomography (CT) of the thorax showed clusters of small nodules in the middle lobe. The bronchial washing specimen showed acid-fast bacilli identified as Mycobacterium intracellulare by DNA-DNA hybridization (DDH) method. This case was diagnosed as Mycobacterium intracellulare lung disease. The patient received combination therapy with rifampicin, ethambutol, and clarithromycin for one year with radiological improvement. CT findings were characteristic and useful for the early diagnosis of MAC infection, which led to cure of the disease by chemotherapy.
Fujiwara
Kiyohiro
K
Department of Thoracic Surgery, National Hospital Organization Shizuoka Fuji National Hospital, 814 Kamiide, Fujinomiya-shi, Shizuoka 418-0103, Japan.
D000995:Antitubercular Agents / Q000008:administration & dosage*; D017291:Clarithromycin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015269:Mycobacterium avium Complex; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000188:drug therapy*; D012293:Rifampin / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed
D000995:Antitubercular Agents; D004977:Ethambutol; D017291:Clarithromycin; D012293:Rifampin