title: Using of multislice helical CT colonography in patients with malignant lesions of colon.
abstract: OBJECTIVE
  To investigate the techniques and clinical applications of multislice helical computed tomography (CT) colonography in colonic lesions.
  
  
  METHODS
  Fifty-nine patients with malignant lesions of colon underwent volume scanning using multislice helical CT. Four types of reconstruction including CT virtual colonoscopy (CTVC), shaded surface display (SSD), Raysum, and multiple planar reconstruction (MPR) were used for image post-processing. The results were compared with those of colonoscopy and pathology.
  
  
  RESULTS
  Multislice helical CT colonography detected 54 colorectal carcinomas, 4 adenomas with focal carcinoma, 1 non-Hodgkin's lymphoma (NHL). The lesions' number, size, location, morphology, stricture of intestinal cavity, infiltration, and metastasis were shown satisfactorily by multislice helical CT colonography. Whole colon could be shown in all patients. CT colonography displayed 4 synchronous colonic tumors, 1 ascending colon carcinoma combined with left renal carcinoma among 54 patients with colonic carcinomas. The accuracy of location of CT colonography was 100%. There were 9 cases that CT showed the tumor location was different from the finding of conventional colonoscopy, while all of the CT location were proven exact by operation. CT colonography also displayed the infiltration of serous layer and fatty tissue in 45 cases; 21 cases matched the pathological results in all the 24 cases of suspicious lymph node metastasis, the sensitivity was 87.5%, the specificity was 90.6%; 9 cases hepatic metastasis, 2 ovarian metastasis, and 1 double adrenal gland metastasis.
  
  
  CONCLUSIONS
  Multislice helical CT colonography is effective in preoperative diagnosis, location, stage, and making treatment plan of colorectal carcinoma. It can display the portion not seen during colonoscopy and may have an adjunctive role.
authors.affiliation: Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730. qinmingwei@hotmail.com
authors.forename: Ming-Wei
authors.initials: MW
authors.lastname: Qin
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Pan
authors.forename: Guan-Ning
authors.initials: GN
authors.lastname: Cong
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
authors.forename: Yun-Qing
authors.initials: YQ
authors.lastname: Zhang
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Mou
authors.forename: Zheng-Yu
authors.initials: ZY
authors.lastname: Jin
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D000236:Adenoma / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000000981:diagnostic imaging*; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic / Q000379:methods*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed