title: Augmentation of implant purchase with bone cements: an in vitro study of injectability and dough distribution.
abstract: Vertebroplasty is widely used to treat (augment) osteoporotic fractures of the spine. This technique--with or without metallic implants--might have more widespread indications, if the mechanics of the injection and distribution of the cement dough through cannulated instruments and implants were better understood. This study was performed to investigate injectability of calcium phosphate and acrylic bone cements through implant prototypes, which featured different perforated sleeve designs. Using a custom-made capillary rheometer, the forces needed to inject 10 mL of the cement dough through standard cannulas were measured in the first series of experiments. In the second series, plastic sleeves were attached to the rheometer, simulating the implant. In both series, the dough was injected into ambient laboratory atmosphere, and in the second series, cement distribution was analyzed by means of an optical system. Injection of cement dough through the cannulas required forces between 50 and 400 N in the case of acrylic cements and between 40 and 500 N in case of the calcium phosphate cements. Using different sleeves did not have a significant influence on the distribution of the cement dough around the sleeve. The amount of cement dough injected was reduced when a perforated implant was attached to the cannula. More material was delivered through the proximal holes of the implant, leading to a V-shaped distribution of the cement dough. Among topics to be investigated in future studies is determination of the injectability of cement dough into trabecular bone or bone-like structures.
authors.affiliation: AO Development Institute, Clavadelerstrasse, CH-7270, Davos Platz, Switzerland. armando.gisep@aofoundation.org
authors.forename: A
authors.initials: A
authors.lastname: Gisep
authors.forename: R
authors.initials: R
authors.lastname: Curtis
authors.forename: M
authors.initials: M
authors.lastname: Hänni
authors.forename: N
authors.initials: N
authors.lastname: Suhm
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001843:Bone Cements / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D006801:Humans; D066298:In Vitro Techniques; D007267:Injections / Q000295:instrumentation / Q000379:methods; D008422:Materials Testing / Q000295:instrumentation / Q000379:methods; D019736:Prostheses and Implants; D016103:Spinal Fractures / Q000601:surgery; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D002130:Calcium Phosphates; C020243:calcium phosphate