title: Candida albicans endocarditis treatment with caspofungin in an HIV-infected patient--case report and review of literature.
abstract: Caspofungin has recently been introduced for the treatment of invasive candidiasis, however, there is limited data on its use in endocarditis. We report a 22-year-old male HIV-infected patient on methadone maintenance therapy that developed right-sided Candida albicans endocarditis. Caspofungin treatment and vegetectomy, followed by fluconazole, was successful in the treatment of our patient. We also review all previous cases of Candida endocarditis treated with caspofungin.
authors.affiliation: Department of HIV/AIDS, University Hospital for Infectious Diseases, Mirogojska 8, 10000 Zagreb, Croatia.
authors.forename: Valentina
authors.initials: V
authors.lastname: Bacak
authors.forename: Bojan
authors.initials: B
authors.lastname: Biocina
authors.forename: Boris
authors.initials: B
authors.lastname: Starcevic
authors.forename: Sarah
authors.initials: S
authors.lastname: Gertler
authors.forename: Josip
authors.initials: J
authors.lastname: Begovac
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002176:Candida albicans / Q000187:drug effects*; D002177:Candidiasis / Q000188:drug therapy* / Q000382:microbiology; D000077336:Caspofungin; D054714:Echinocandins; D004696:Endocarditis / Q000188:drug therapy* / Q000382:microbiology; D015658:HIV Infections / Q000150:complications; D006801:Humans; D055666:Lipopeptides; D008297:Male; D010456:Peptides, Cyclic / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D000077336:Caspofungin