[Experimental assessment of the capacities of use of photosense. Communication 1. Fluorescence diagnosis of epibulbar and choroid tumors].
Whether Photosense (PS) may be used in the fluorescence diagnosis (FD) of experimental epibulbar and choroid tumors is discussed. The fluorescent ability of Photosense in FD permits detection of advanced malignancies. The kinetics of concentration of PS and the selectivity of its accumulation in malignant versus normal tissues were investigated. PS is shown to be an effective photosensitizer in the FD and, possibly, photodynamic therapy of tumors.
Budzinskaia
M V
MV
Likhvantseva
V G
VG
Shevchik
S A
SA
Loshchenov
V B
VB
Kuz'min
S G
SG
Vorozhtsov
G N
GN
D000818:Animals; D002830:Choroid Neoplasms / Q000175:diagnosis*; D004596:Electroretinography; D005134:Eye Neoplasms / Q000175:diagnosis*; D005456:Fluorescent Dyes; D007211:Indoles / Q000493:pharmacokinetics; D008297:Male; D008546:Melanoma, Experimental / Q000175:diagnosis*; D009942:Organometallic Compounds / Q000493:pharmacokinetics; D011817:Rabbits; D012984:Software
D005456:Fluorescent Dyes; D007211:Indoles; D009942:Organometallic Compounds; C048577:aluminum tetrasulfophthalocyanine