title: Four new cucurbitane glycosides from Hemsleya jinfushanensis.
abstract: A phytochemical study of the tubers of Hemsleya jinfushanensis L. T. Shen resulted in the isolation of four new cucurbitane glycosides, jinfushanosides A-D (1- 4), as well as four known compounds 5-8. Compounds 1-7 were tested for bioactivity against rabbit platelet aggregation induced by PAF, ADP, or AA. Among them, compounds 1, 5, 6 and 7 weakly inhibited PAF-induced platelet aggregation.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, the Chinese Academy of Sciences, 610 Longquan Road, Kunming, Yunnan, P.R. China.
authors.forename: Jian-Chao
authors.initials: JC
authors.lastname: Chen
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Niu
authors.forename: Zhong-Rong
authors.initials: ZR
authors.lastname: Li
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Qiu
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D019662:Cucurbitaceae; D006027:Glycosides / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D011817:Rabbits
chemical_list: D000596:Amino Acids; D006027:Glycosides; D010936:Plant Extracts; D010975:Platelet Aggregation Inhibitors; C014427:cucurbitine