title: Unexpected and expeditious entry into trifluoromethyl aziridines from substituted beta-dicarbonyl compounds.
abstract: [Reaction: see text]. One-pot aziridinations were obtained starting from substituted 2,2,2-trifluoroethyl beta-dicarbonyl compounds with nosyloxycarbamates in the presence of an excess of CaO as base. The unexpected ring closure reaction takes place at room temperature, leading to the N-protected alpha-trifluoromethyl aziridines with good yields. The reaction pathway seems to be influenced by the choice of the base.
authors.affiliation: Dipartimento di Chimica, Università degli Studi La Sapienza, Piazzale Aldo Moro 2, I-00185 Roma, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Colantoni
authors.forename: Stefania
authors.initials: S
authors.lastname: Fioravanti
authors.forename: Lucio
authors.initials: L
authors.lastname: Pellacani
authors.forename: Paolo A
authors.initials: PA
authors.lastname: Tardella