title: Malignant hypertension with intestinal ischemia secondary to juxtaglomerular cell tumor.
abstract: Malignant hypertension is a well-defined condition associated with high blood pressure and acute target-organ damage. Although 95% of cases are secondary to essential hypertension, its etiological profile is broad. Juxtaglomerular cell tumor is a rare condition, with only approximately 65 cases reported to date. We describe a patient with malignant hypertension with acute renal failure and intestinal ischemia secondary to a juxtaglomerular cell tumor. We believe this is the first case of juxtaglomerular cell tumor causing malignant hypertension. The diagnostic approach and treatment are discussed.
authors.affiliation: Nephrology Division, Department of Pathology, University of São Paulo School of Medicine, Hospital das Clínicas, Brazil. alexandreliborio@yahoo.com.br
authors.forename: Alexandre Braga
authors.initials: AB
authors.lastname: Libório
authors.forename: Flávio de Oliveira
authors.initials: Fde O
authors.lastname: Marques
authors.forename: Leonardo
authors.initials: L
authors.lastname: Testagrossa
authors.forename: Cléber Aparecido
authors.initials: CA
authors.lastname: Leite
authors.forename: Aurileide Alves
authors.initials: AA
authors.lastname: Leitão
authors.forename: José Nery
authors.initials: JN
authors.lastname: Praxedes
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology; D058186:Acute Kidney Injury / Q000209:etiology; D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D000328:Adult; D017311:Amlodipine / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D020773:Headache Disorders / Q000209:etiology; D006801:Humans; D006974:Hypertension, Malignant / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D017379:Hypertrophy, Left Ventricular / Q000209:etiology; D007422:Intestines / Q000098:blood supply* / Q000473:pathology; D007511:Ischemia / Q000209:etiology*; D007606:Juxtaglomerular Apparatus / Q000378:metabolism*; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D009336:Necrosis; D009392:Nephrectomy; D010211:Papilledema / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D012083:Renin / Q000378:metabolism*; D012166:Retinal Hemorrhage / Q000209:etiology
chemical_list: D000959:Antihypertensive Agents; D017311:Amlodipine; D012083:Renin