Enantioselective conjugate addition of phenylboronic acid to enones catalysed by a chiral tropos/atropos rhodium complex at the coalescence temperature.
A highly enantioselective rhodium-catalysed conjugate addition of phenylboronic acid to cyclic enones has been achieved using a dynamic library of chiral phosphorus ligands; the tropos/atropos nature of the ligands in the rhodium complex has been characterised via 31P-NMR.
Monti
Chiara
C
Dipartimento di Chimica Organica e Industriale, Centro di Eccellenza C. I. S. I., Università degli Studi di Milano, Istituto di Scienze e Tecnologie Molecolari (ISTM) del CNR, Via G. Venezian 21, Milan 20133, Italy.
Gennari
Cesare
C
Piarulli
Umberto
U