[Follow-up study in endovascular therapy for the renal artery stenosis].
OBJECTIVE
To evaluate the safety and efficacy of endovascular therapy for renal artery stenosis.


METHODS
Percutaneous transluminal renal angioplasty with stent (PTRAS) was performed on 33 consecutive patients with severe renal artery stenosis who suffered from poorly controlled hypertension or renal dysfunction. They were subsequently underwent 7 to 49 months clinical follow up for the effect of the procedure on renal function, blood pressure control, mortality.


RESULTS
Angiographic success was obtained in 32 (97.0%) of the 33 patients. The mortality was 18.2%. After PTRAS, two (6.1%) died of myocardial infarction within 4 months. Four (12.1%) patients with preoperative serum creatinine (Scr) > or = 177 micromol/L died of uraemia within 17 approximately 28 months. Twelve and twenty-four months after the procedure, systolic and diastolic blood pressure of 26 (78.8%) cases with preoperative Scr < 177 micromol/L significantly decreased (P < 0.05), with less antihypertensive medications taken and satisfactory renal function.


CONCLUSIONS
For patients without serious cardiorenal disease, PTRAS has a beneficial effect on blood pressure and renal function. For patients with serious cardiorenal disease or preoperative Scr > or = 177 micromol/L, the mortality is higher. PTRAS should be performed prudently. The preservation of renal function may be enhance by using renal protection device.
Wang
Ke-qin
KQ
Department of Vascular Surgery, Chaoyang Hospital, Capital University of Medical Sciences, Beijing 100020, China. wkeqin2003@yahoo.com.cn
Yuan
Chao
C
Zhang
Wang-de
WD
Yuan
Biao
B
Xing
Tong
T
Li
Tan
T
Zhang
Yang
Y
Song
Sheng-han
SH
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000150:complications / Q000628:therapy*; D051437:Renal Insufficiency / Q000209:etiology; D015607:Stents; D016896:Treatment Outcome