[Morphological changes in the lungs and characteristics of thromboemboli in patients with thromboembolism of the pulmonary artery].
Basing on results of pathologoanatomical investigations, performed in 26 cases, the lungs changes in pulmonary thromboembolism were analyzed. It was shown, that an acute thromboembolism of a. pulmonalis main branches did not cause an acute necrosis of pulmonary alveolar tissue, but induces progressive diffuse changes of their microcircular bed, concomitant with pulmonary hypertension. In cases of chronical pulmonary thromboembolism the diffuse vascular sclerosis of the nonaffected lung and the alveolar tissue emphysema are formed, and in such cases the signs of pulmonary hypertension showing hypertrophy of the muscular vessels middle layer as well as their intima hyperplasia are revealed. This determines the expediency of earlier start of thrombolytic therapy conduction as well as surgical intervention in an acute pulmonary thromboembolism.
Todurov
B M
BM
Zakharova
V P
VP
Onishchenko
V F
VF
Mazur
A P
AP
Kovtun
H I
HI
Kuz'mych
I M
IM
D001344:Autopsy; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D011651:Pulmonary Artery / Q000473:pathology*; D011655:Pulmonary Embolism / Q000473:pathology* / Q000601:surgery; D017131:Thrombectomy