title: Serum soluble transferrin receptor is a valuable diagnostic tool in iron deficiency of breath-holding spells.
abstract: Iron-deficiency anemia may be a factor contributing to breath-holding spells. The serum transferrin receptor provides a useful measure of tissue iron deficiency. In this study of 50 breath-holders, while iron-deficiency anemia was detected in 28 (56%) of patients with routine tests, serum transferrin receptor levels were found increased in all patients. A positive correlation was detected between serum soluble transferrin receptor levels and frequency of attacks. It is suggested that the serum transferrin receptor level is useful as a single test for identification of iron deficiency in breath-holders. Moreover, if iron deficiency can be diagnosed earlier, then patients can be treated earlier.
authors.affiliation: Pediatrics and Biostatistics Departments, Ankara University, Ankara, Turkey. handanprl@hotmail.com
authors.forename: Uğur
authors.initials: U
authors.lastname: Handan
authors.forename: Cin
authors.initials: C
authors.lastname: Sükrü
authors.forename: Deda
authors.initials: D
authors.lastname: Gülhis
authors.forename: Gökçe
authors.initials: G
authors.lastname: Hafize
authors.forename: Elhan H
authors.initials: EH
authors.lastname: Atilla
authors.forename: Akar
authors.initials: A
authors.lastname: Nejat
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000150:complications / Q000188:drug therapy; D001049:Apnea / Q000097:blood* / Q000209:etiology; D002675:Child, Preschool; D005260:Female; D005296:Ferrous Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D011237:Predictive Value of Tests; D011990:Receptors, Transferrin / Q000097:blood*; D012120:Respiration Disorders / Q000097:blood* / Q000150:complications / Q000188:drug therapy; D012995:Solubility
chemical_list: D005296:Ferrous Compounds; D011990:Receptors, Transferrin; C020748:ferrous sulfate