Locked pi-expanded chlorins in two steps from simple tetraarylporphyrins.
[reaction: see text] Upon tandem Reformatsky reaction, easily accessible porphyrinic ketones give "locked" chlorinic diester. Both ketones and diesters, as bases or palladium complexes, efficiently generate singlet dioxygen, as demonstrated by trapping with cholesterol.
Fouchet
Julien
J
U.M.R. 7177 du C.N.R.S., Faculté de Chimie, Université Louis Pasteur, 1, Rue Blaise Pascal, F-67000 Strasbourg, France.
Jeandon
Christophe
C
Ruppert
Romain
R
Callot
Henry J
HJ