title: Relaxometric study of copper [15]metallacrown-5 gadolinium complexes derived from alpha-aminohydroxamic acids.
abstract: Proton nuclear magnetic relaxation dispersion (NMRD) profiles were recorded between 0.24 mT and 1.4 T for lanthanum(III)- and gadolinium(III)-containing [15]metallacrown-5 complexes derived from alpha-aminohydroxamic acids and with copper(II) as the ring metal. The influence of the different R-groups on the proton relaxivity was investigated, and a linear relationship between the relaxivity and the molecular mass of the metallacrown complex was found. The selectivity of the metallacrown complexes was tested by transmetalation experiments with zinc(II) ions. The crystal structure of the copper [15]metallacrown-5 gadolinium complex with glycine hydroximate ligands is reported.
authors.affiliation: Katholieke Universiteit Leuven, Department of Chemistry, Celestijnenlaan 200F, 3001 Leuven, Belgium.
authors.forename: Tatjana N
authors.initials: TN
authors.lastname: Parac-Vogt
authors.forename: Antoine
authors.initials: A
authors.lastname: Pacco
authors.forename: Peter
authors.initials: P
authors.lastname: Nockemann
authors.forename: Sophie
authors.initials: S
authors.lastname: Laurent
authors.forename: Robert N
authors.initials: RN
authors.lastname: Muller
authors.forename: Mathias
authors.initials: M
authors.lastname: Wickleder
authors.forename: Gerd
authors.initials: G
authors.lastname: Meyer
authors.forename: Luce
authors.initials: L
authors.lastname: Vander Elst
authors.forename: Koen
authors.initials: K
authors.lastname: Binnemans
mesh_terms: D003300:Copper / Q000737:chemistry*; D005682:Gadolinium / Q000737:chemistry*; D006877:Hydroxamic Acids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D006877:Hydroxamic Acids; D009942:Organometallic Compounds; D003300:Copper; D005682:Gadolinium; D015032:Zinc