title: Peripheral neuropathies associated with HIV and hepatitis C co-infection: a review.
abstract: Co-infection with HIV and hepatitis C has become increasingly prevalent. It is a major source of morbidity in HIV-infected populations. Distal symmetric polyneuropathy is the most common form of peripheral neuropathy in HIV as well as hepatitis C mono-infection. There is considerable overlap in the symptoms and signs of HIV and hepatitis C neuropathy. It is not known whether there are additive or synergistic effects on the peripheral nerve by these two viruses. There is a need for studies to further elucidate the mechanisms involved.
authors.affiliation: Department of Neurology (NeuroAIDS Research Program), Mount Sinai Medical Center, New York, NY 10029, USA.
authors.forename: Lydia B
authors.initials: LB
authors.lastname: Estanislao
authors.forename: Susan
authors.initials: S
authors.lastname: Morgello
authors.forename: David M
authors.initials: DM
authors.lastname: Simpson
mesh_terms: D020275:Guillain-Barre Syndrome / Q000821:virology; D015658:HIV Infections / Q000150:complications*; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D020422:Mononeuropathies / Q000821:virology; D010523:Peripheral Nervous System Diseases / Q000821:virology*; D011128:Polyradiculopathy / Q000821:virology