title: [Innovative concepts in early cancer detection and staging of localized prostate cancer].
abstract: Prostate cancer is the most common malignancy in males. Men aged 50 years and older are recommended to undergo an annual digital rectal examination (DRE) and determination of prostate-specific antigen (PSA) in serum for early detection. Fortunately, disease-specific mortality continues to decline as a result of advances in screening, staging, and patient awareness. However, about 30% of men with a clinically organ-confined disease show evidence of extracapsular extension or seminal vesicle invasion on pathological analysis. Consequently, there is a need for more accurate diagnostic tools for planning tailored treatment. A variety of modern imaging techniques has been implemented in an attempt to obtain more precise staging, thereby allowing for more detailed counseling, and instituting optimum therapy. This review highlights developments in prostate cancer imaging that may improve staging and treatment planning for prostate cancer patients.
authors.affiliation: Abteilung Urologie und Kinderurologie, Universitätsklinikum, Ulm. ludwig.rinnab@medizin.uni-ulm.de
authors.forename: L
authors.initials: L
authors.lastname: Rinnab
authors.forename: R
authors.initials: R
authors.lastname: Küfer
authors.forename: R E
authors.initials: RE
authors.lastname: Hautmann
authors.forename: B G
authors.initials: BG
authors.lastname: Volkmer
authors.forename: M
authors.initials: M
authors.lastname: Straub
authors.forename: N M
authors.initials: NM
authors.lastname: Blumstein
authors.forename: H W
authors.initials: HW
authors.lastname: Gottfried
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D003952:Diagnostic Imaging / Q000379:methods* / Q000639:trends*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000639:trends; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D013673:Technology Assessment, Biomedical
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen