title: Large simple trials in psychiatry: providing reliable answers to important clinical questions.
authors.forename: John R
authors.initials: JR
authors.lastname: Geddes
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003657:Decision Making; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D011570:Psychiatry / Q000379:methods*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D002800:Cholinesterase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors