Effect of oxygen concentration during the incubation of embryos of women undergoing ICSI and embryo transfer: a prospective randomized study.
The hypothesis that ICSI outcome can be improved by culturing human embryos in an atmosphere of controlled O(2) concentration (5%) compared with 20% was tested in a prospective randomized study of 712 transfer cycles. The cycle characteristics and the embryology parameters were similar between groups. The embryo qualities were similar with day 2 transfers; however, they were better with day 3 transfers incubated in 5% O(2) than in 20% O(2). The clinical outcome parameters did not differ between groups according to the O(2) concentration. The results indicated that culture of embryos under atmospheric conditions of O(2) for the first 2 or 3 days did not alter the clinical outcome in ICSI cycles.
Bahçeci
Mustafa
M
Bahçeci Women Health Care Centre and German Hospital at Istanbul, Istanbul, Turkey. mbahceci@superonline.com
Ciray
H Nadir
HN
Karagenc
Levent
L
Uluğ
Ulun
U
Bener
Faruk
F
D001755:Blastocyst; D002478:Cells, Cultured; D010064:Embryo Implantation; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000166:cytology / Q000378:metabolism*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D008297:Male; D009865:Oocytes / Q000166:cytology / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D013997:Time Factors
D010100:Oxygen