title: Pyogenic meningitis in Ilesa, Nigeria.
abstract: This study was conducted in 124 children with meningitis to review the etiology, antimicrobial susceptibility and outcome of disease in a Nigerian tertiary health facility. Of these, 97 (78.27%) were culture positive; in the rest 27(21.8%), diagnosis was based on Gram staining of the CSF. Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Staphylococcus aureus and Escherichia coli were isolated in 33.9%, 33.9%, 5.6%, 2.4%, and 2.4% samples respectively. All the isolates had 100 percent; sensitivity to both ceftriaxone and ciprofloxacin while the sensitivities to penicillin and ampicillin were remarkably low. The mortality was 33/124 (26.6%) while 16/ 91 (17.6%) of the survivors had various neurologic sequelae.
authors.affiliation: Department of Pediatrics, Wesley Guild Hospital, Ilesa, Osun State, Nigeria. tinuade_ogunlesi@yahoo.co.uk
authors.forename: T A
authors.initials: TA
authors.lastname: Ogunlesi
authors.forename: J A O
authors.initials: JA
authors.lastname: Okeniyi
authors.forename: O A
authors.initials: OA
authors.lastname: Oyelami
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D009549:Nigeria / Q000453:epidemiology; D012621:Seasons; D017678:Sex Distribution
chemical_list: D000900:Anti-Bacterial Agents