title: [Glucocorticosteroids in the treatment of subglottic laryngitis in children].
abstract: Subglottic laryngitis is one of the acute children's diseases, directly caused by a violently growing edema of the subglottic area. Its symptoms generally appear very suddenly, when children seem to be in perfect health, at night, several hours after falling asleep. Their symptoms included barking cough, clear voice, stridor, inspiratory dyspnoea with participation of auxiliary respiratory muscles, excitation and anxiety of a child, changes in skin coloration. The movement of the wings of the nostrils is intensified. In especially severe cases, agitation, cyanosis, pallor of skin, obnubilation, apnea, loss of consciousness and circulatory failure may also occur. Subglottic laryngitis is a disease, which can threaten the life of a small child. The aim of this study was to observe efficacy of the treatment of the subglottic laryngitis with glucocorticoids, especially budesonide in nebulization. The research covered 169 children: 58 girls (34.31%) and 111 boys (65.69%) aged 9. months do 5. years (mean 3 years 6 months) hospitalized in the Children's Hospital in Warsaw with the following symptoms: dry barking cough, stridor, inspiratory dyspnoea with the participation of auxiliary respiratory muscles, agitation and change of colour of skin. The examination of each patient included subjective, objective (pediatric and laryngological). Disease severity was assessed by a clinical croup score based on stridor, cough retractions, dyspnoea and cyanosis and the overall clinical assessment was scored on a visual scale. The results indicate that nebulised budesonide can be used as a safe and effective alternative treatment in children with moderate to severe subglottic laryngitis.
authors.affiliation: Oddział Otolaryngologiczny, SZPZOZ im. Prof. J. Bogdanowicza w Warszawie.
authors.forename: Beata
authors.initials: B
authors.lastname: Zielnik-Jurkiewicz
mesh_terms: D000280:Administration, Inhalation; D019819:Budesonide / Q000008:administration & dosage / Q000627:therapeutic use*; D002675:Child, Preschool; D003371:Cough / Q000209:etiology; D003490:Cyanosis / Q000209:etiology; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007827:Laryngitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D012135:Respiratory Sounds / Q000209:etiology; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D019819:Budesonide