The emergence of chemical genomics in drug discovery.
The interaction of small organic molecules with proteins and other macromolecules is fundamental to drug action. Chemical genomics employs a combination of chemistry, genomics and informatics to study these drug-target interactions in a systematic and global manner in order to improve the efficiency of the drug discovery process.
Zanders
Edward D
ED
CamBP Ltd, St John's Innovation Centre, Cambridge, UK. ed.zanders@cambp.com
Gordon
Robert D
RD
Gershater
Craig J L
CJ
D000818:Animals; D002626:Chemistry, Pharmaceutical; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D004345:Drug Industry; D023281:Genomics; D006801:Humans; D040901:Proteomics