[Lens-sparing external beam radiotherapy of periocular lymphomas].
OBJECTIVE
The presentation of techniques and results of lens-sparing external beam radiotherapy of patients with ophthalmologic lymphomas.


METHODS
From 1991 to 2001, at the Department of Radiotherapy of the National Institute of Oncology, Budapest, 92 patients with periocular lymphomas were treated by photon and/or electron beam irradiation depending on the localization. Mean age was 63 years (range: 26-89 years) and the male/female ratio was 1.3. According to the Ann Arbor classification, 72% were in stage I.E. Histologically 85 patients (92.4%) were Grade I while 7 patients (7.6%) presented with higher grade disease. In case of low-grade lymphoma, a dose of 24-32 Gy was delivered, and for higher grade of malignancy we applied 34-40 Gy total dose, using 1.8-2 Gy daily fractions.


RESULTS
The local remission rate was 94.4% (CR: 78.8% and PR: 15.6%). There was no change in 2.3%, and 3.3% showed progression. Mild and intermediate acute side effects occurred in 28%, and the incidence of chronic late complications was 3%.


CONCLUSIONS
External beam radiotherapy applying lens-sparing methods is safe and effective in the treatment of periocular lymphomas.
Bajcsay
András
A
Országos Onkológiai Intézet, Sugárterápiás Osztály, Budapest, Ráth György. bajcsay@oncol.hu
Kontra
Gábor
G
Forgács
Gyula
G
Fodor
János
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000528:radiation effects*; D008223:Lymphoma / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control*; D011835:Radiation Protection / Q000379:methods*; D011878:Radiotherapy / Q000379:methods; D016896:Treatment Outcome