title: Congenital hemicerebral anomaly in a stranded Pacific harbor seal (Phoca vitulina richardsi).
abstract: A stranded 5-month-old female Pacific harbor seal (Phoca vitulina richardsi) was presented displaying tachypnea and diminished lung sounds. No neurological abnormalities were noted. The animal was treated for verminous pneumonia, but died 2 wk later. Gross necropsy examination revealed a severe obstructive verminous pneumonia associated with large numbers of Otostrongylus circumlitus. In addition, the majority of the right cerebral hemisphere was absent, with hypoplasia of the left cerebellar hemisphere, absence of the right pyramid, and malformation of the right occipital bone. Histopathologic findings included multifocal thrombosis and inflammation of pulmonary arteries, verminous pneumonia, and mild vacuolation of the subependymal white matter in the third ventricle representing swelling of myelin sheaths and edema. This is the first report of a hemicerebral anomaly in a marine mammal.
authors.affiliation: The Marine Mammal Center, Marin Headlands, 1065 Fort Cronkhite, Sausalito, CA 94965, USA.
authors.forename: Christy A
authors.initials: CA
authors.lastname: McKnight
authors.forename: Taylor L
authors.initials: TL
authors.lastname: Reynolds
authors.forename: Martin
authors.initials: M
authors.lastname: Haulena
authors.forename: Alexander
authors.initials: A
authors.lastname: deLahunta
authors.forename: Frances M D
authors.initials: FM
authors.lastname: Gulland
mesh_terms: D000818:Animals; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006849:Hydrocephalus / Q000209:etiology; D008681:Metastrongyloidea / Q000302:isolation & purification; D046049:Phoca / Q000002:abnormalities*; D017206:Strongylida Infections / Q000175:diagnosis / Q000662:veterinary