title: Perifolliculitis capitis abscedens et suffodiens.
abstract: Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing. We report a case of 29-year-old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient was treated with periodic incision and drainage of the scalp abscesses. The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal. A response to treatment was excellent and rapid. The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS.
authors.affiliation: Department of Dermatology and Venereology, Zagreb University Hospital Center, Croatia. susana.ljubojevic@zg.htnet.hr
authors.forename: S
authors.initials: S
authors.lastname: Ljubojevic
authors.forename: A
authors.initials: A
authors.lastname: Pasic
authors.forename: J
authors.initials: J
authors.lastname: Lipozencic
authors.forename: M
authors.initials: M
authors.lastname: Skerlev
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000505:Alopecia / Q000209:etiology; D005499:Folliculitis / Q000188:drug therapy*; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D012536:Scalp Dermatoses / Q000188:drug therapy*; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D007641:Keratolytic Agents; D014212:Tretinoin