title: Hematometra in a patient with Cornelia De Lange syndrome.
abstract: BACKGROUND
  Hematometra is usually the result of developmental anomalies or may be secondary to cervical obstruction. Abnormal uterine contractile function (atony) would be an uncommon cause of hematometra.
  
  
  METHODS
  An 18-year-old female with Cornelia De Lange syndrome and abdominal pain was found to have a hematometra on ultrasound examination. On pelvic examination, her cervical canal was patent and was easily dilated, but the hematometra did not drain until suprapubic pressure was applied. Two weeks postoperatively, pelvic magnetic resonance imaging showed a markedly thinned uterine myometrium and a recurrent hematometra, prompting the decision to perform a hysterectomy.
  
  
  CONCLUSIONS
  Hematometra in a patient with Cornelia De Lange syndrome may be the result of abnormal uterine contractile function.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Reproductive Medicine and Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22903, USA.
authors.forename: Joseph O
authors.initials: JO
authors.lastname: Doyle
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Williams
authors.forename: Colleen A
authors.initials: CA
authors.lastname: Raymond
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000293:Adolescent; D003635:De Lange Syndrome / Q000150:complications*; D005260:Female; D006409:Hematometra / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007044:Hysterectomy; D012008:Recurrence; D014463:Ultrasonography; D014590:Uterine Contraction