[Clinical comparison on the classical versus extensive Whipple's resection for adenocarcinoma of head of pancreas].
OBJECTIVE
To evaluate the effect of extensive Whipple's resection to the adenocarcinoma of head of pancreas on the survival, complications, and surgical mortality.


METHODS
Ninety three patients who received Whipple's surgery between January 1995 and March 2003 were divided into classical group (n = 51) and extensive group (n = 42). Their short-term outcome and survival rate were compared retrospectively.


RESULTS
The postoperative complication rate and mortality in classical group and extensive group were 19.61%/3.92% and 16.67%/2.38%, respectively. And 1- and 2- year survival rates in classical group and extensive group were 58.82%/20.59% and 63.33%/23.33%, respectively.


CONCLUSIONS
Postoperative complications and mortality will not increase in extensive Whipple's resection for adenocarcinoma of head of pancreas. However, whether extensive Whipple's resection will improve long-term survival still requires further investigation.
Liu
Xu-bao
XB
Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. xbliu61@yahoo.com
Yan
Lü-nan
LN
Zhai
Hong-jun
HJ
Lu
Bing
B
Hu
Wei-ming
WM
Tian
Bo-le
BL
Zhang
Zhao-da
ZD
D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate