Effect of "external" superoxide anion on apoptosis in coleoptiles of wheat seedlings.
A derivative of phthalic acid, dibutylphthalate (DBP), which has gametocidal effect at the concentration of approximately 10(-4) M, increased apoptosis in coleoptiles of wheat seedlings. This was associated with activation of chromatin margination and generation of mitochondria-containing vesicles. At the same concentration, DBP activated the release by the coleoptiles of superoxide anion into the environment. Lower (10(-5) M) and higher (10(-3) M) concentrations of DBP virtually had no effect on either process. A probable mechanism of effect of the "external" superoxide anion on apoptosis within the plant cell is discussed.
Vorobjev
A A
AA
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119899, Russia.
Smirnova
E G
EG
Bakeeva
L E
LE
Yaguzhinsky
L S
LS
D000975:Antioxidants / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D042002:Chromatin Assembly and Disassembly / Q000502:physiology; D018548:Cotyledon / Q000166:cytology* / Q000187:drug effects; D003993:Dibutyl Phthalate / Q000494:pharmacology; D008928:Mitochondria / Q000187:drug effects / Q000648:ultrastructure; D010795:Phthalic Acids / Q000494:pharmacology; D036226:Seedlings / Q000166:cytology* / Q000254:growth & development; D013481:Superoxides / Q000494:pharmacology*
D000975:Antioxidants; D010795:Phthalic Acids; D013481:Superoxides; D003993:Dibutyl Phthalate; C032279:phthalic acid