title: GASepo-a software solution for quantitative analysis of digital images in Epo doping control.
abstract: A software has been developed that is aimed at quantitative analysis of images acquired by isoelectric focusing and double blotting procedures used for recombinant erythropoietin doping control. It represents a unified and easy-to-use tool for Epo doping experts in WADA accredited laboratories. It is based on image segmentation philosophy that enables identification of individual bands whose characteristics are needed for evaluation of the Epo doping positivity criteria. Several modules implemented in the GASepo software include an original know how, in particular, the method of robust calculation of the cut-off line, band segmentation and classification algorithms. GASepo is being used in several doping control laboratories worldwide.
authors.affiliation: Department of High Performance Image Processing, ARC Seibersdorf Research GmbH, A-2444, Austria. ivan.bajla@arcs.ac.at
authors.forename: I
authors.initials: I
authors.lastname: Bajla
authors.forename: I
authors.initials: I
authors.lastname: Holländer
authors.forename: M
authors.initials: M
authors.lastname: Minichmayr
authors.forename: G
authors.initials: G
authors.lastname: Gmeiner
authors.forename: Ch
authors.initials: Ch
authors.lastname: Reichel
mesh_terms: D000465:Algorithms; D004300:Doping in Sports / Q000517:prevention & control*; D004921:Erythropoietin / Q000097:blood*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007118:Immunoassay / Q000379:methods*; D007525:Isoelectric Focusing / Q000379:methods; D011994:Recombinant Proteins / Q000097:blood; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013050:Spectrometry, Fluorescence / Q000379:methods; D015813:Substance Abuse Detection / Q000379:methods*; D014584:User-Computer Interface
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin