[Immunohistochemical markers in colorectal cancer].
In colorectal cancer, immunohistochemical staining can routinely be used for tumour classification, screening for defective DNA mismatch repair and possibly identification of markers relevant to prediction of outcome of chemotherapy. This article provides a brief description of these applications.
Lindebjerg
Jan
J
Vejle Sygehus, Patologisk Afdeling, DK-7100 Vejle. janlin@vgs.vejleamt.dk
D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism; D020137:Base Pair Mismatch; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002277:Carcinoma / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics; D004268:DNA-Binding Proteins / Q000378:metabolism; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D051719:MutS DNA Mismatch-Binding Protein
D001426:Bacterial Proteins; D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; D000251:Adenosine Triphosphatases; D051719:MutS DNA Mismatch-Binding Protein