Sulfone coupling and double-elimination strategy for carotenoid synthesis.
[Reaction: see text]. A highly efficient synthetic method of carotenoid compounds has been developed on the basis of the sulfone coupling and double-elimination strategy. This method highlighted the sulfone-mediated coupling with the novel C(10) dialdehyde, 2,7-dimethyl-4-octenedial, which was easily prepared and efficiently utilized in the synthesis of the conjugated polyene chains.
Guha
Samar Kumar
SK
Department of Chemistry, Myong Ji University, Yongin, Kyunggi-Do 449-728, Korea.
Koo
Sangho
S
D002338:Carotenoids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013450:Sulfones / Q000737:chemistry*
D013450:Sulfones; D002338:Carotenoids