title: Metastatic gastric adenocarcinoma presenting as an enlarging plaque on the scalp.
abstract: We present a case report of metastatic gastric adenocarcinoma in which the cutaneous metastases were the first sign of disease recurrence. A 73-year-old man presented with painless red plaques on his scalp and forehead. He was diagnosed with gastric carcinoma with metastases to perigastric lymph nodes 3 1/2 years earlier. Histopathology results revealed signet-ring cells consistent with gastric adenocarcinoma. The patient failed to respond to treatment with intralesional interleukin 2, previously reported to be effective, and expired 7 months later.
authors.affiliation: Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
authors.forename: Oren H
authors.initials: OH
authors.lastname: Lifshitz
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Berlin
authors.forename: James S
authors.initials: JS
authors.lastname: Taylor
authors.forename: Wilma F
authors.initials: WF
authors.lastname: Bergfeld
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D001706:Biopsy; D004890:Erythema / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012535:Scalp / Q000473:pathology; D012536:Scalp Dermatoses / Q000473:pathology* / Q000628:therapy; D012878:Skin Neoplasms / Q000556:secondary* / Q000628:therapy; D013274:Stomach Neoplasms / Q000473:pathology*