Recent advances in uterine fibroid embolization.
OBJECTIVE
To summarize the literature on uterine embolization for fibroids published in 2004 and 2005.


RESULTS
During the last two years, our understanding of the outcome of uterine fibroid embolization has increased. The outcomes are comparable to those that occur after hysterectomy. Health-related quality-of-life studies have confirmed the positive impact of the procedure. Improvement in menorrhagia has been quantified using the alkaline hematin method, objectively confirming the outcome. Recovery is also better understood and quantified, with most patients experiencing only moderate pain over the first few days after embolization. In two pregnancy-outcome studies, an increased frequency of cesarean section occurred and possibly a greater likelihood of abnormal placentation, although the data are too few to draw conclusions at this time. Contrast-enhanced magnetic resonance imaging (MRI) has emerged as the primary tool for assessing the potential of complications following the procedure, and our understanding of vaginal discharge and uterine infarction has been increased as a result of its use.


CONCLUSIONS
Within the last few years, uterine embolization has become an accepted therapy for uterine fibroids. The increase in understanding gained in recent years has helped to confirm the effectiveness and relative tolerability of this therapy.
Spies
James B
JB
Department of Radiology, Georgetown University Hospital, Washington, DC 20007, USA. spiesj@gunet.georgetown.edu
Patel
Amee A
AA
Epstein
Nathan B
NB
White
Amy M
AM
D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D007889:Leiomyoma / Q000628:therapy*; D011183:Postoperative Complications; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000628:therapy*