Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+.
Biagini
Giancarlo A
GA
Fidock
David A
DA
Bray
Patrick G
PG
Ward
Stephen A
SA
D018528:ATP-Binding Cassette Transporters / Q000235:genetics / Q000502:physiology*; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D002738:Chloroquine / Q000494:pharmacology*; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D026901:Membrane Transport Proteins; D009154:Mutation; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics; D015800:Protozoan Proteins / Q000235:genetics / Q000502:physiology*; D014617:Vacuoles / Q000378:metabolism*
D018528:ATP-Binding Cassette Transporters; D000962:Antimalarials; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; C416369:PfCRT protein, Plasmodium falciparum; D015800:Protozoan Proteins; C059987:mdr gene protein, Plasmodium; D002738:Chloroquine; D002118:Calcium