Comparisons and homology in adult and developing vertebrate central nervous systems.
Comparisons of characters in both adult and developing vertebrate central nervous systems require an understanding of the concept of homology. This article begins with a definition of homology in adult animals and then discusses criteria and methodology used to make appropriate comparisons of characters at a variety of hierarchical levels. Crucial to such an analysis is the methodology employed by neurocladistics to ensure meaningful comparisons. Then, a similar approach is used to address these identical problems in embryos. Concerns unique to comparisons of developing central nervous systems are enumerated. In addition, a number of special features of central nervous system formation and organization in both adults and embryos are discussed within the framework of homology and neurocladistics. Lastly, the concept of field homology as applied to vertebrate central nervous system characters is addressed.
Pritz
Michael B
MB
Department of Neurological Surgery, Indiana University School of Medicine, 545 Barnhill Drive, EH 141, Indianapolis, IN 46202-5124, USA. mpritz@iupui.edu
D000818:Animals; D002490:Central Nervous System / Q000196:embryology / Q000254:growth & development*; D005260:Female; D006801:Humans; D011247:Pregnancy; D013045:Species Specificity; D009626:Terminology as Topic; D014714:Vertebrates