Non-Aspergillus fungal pneumonia in transplant recipients.
Although species of Aspergillus and Candida account for most deeply invasive and life-threatening fungal infections, the past decades have seen a rise in the immunocompromised population. With this increase, additional fungi have emerged as important agents of morbidity and mortality. These opportunistic fungi are characterized by their ubiquitous presence in the environment, their ability to cause disease in immunosuppressed patients, and their diminished susceptibility to the currently available antifungal agents. Pneumonia, one aspect of a myriad of clinical manifestations caused by these fungal pathogens, is discussed in this article.
Costa
Sylvia F
SF
Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Alexander
Barbara D
BD
D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000209:etiology* / Q000382:microbiology; D016377:Organ Transplantation / Q000009:adverse effects*