[Update in the research of gene therapy for pancreatic carcinoma].
With the advances in immunology and molecular biology, new recognition in the pathogenesis, progression, and metastasis of carcinoma have been achieved. Studies on gene therapy for pancreatic carcinoma have been attempted in different ways, such as inhibiting oncogene, activating tumor suppressor gene, inducing apoptosis, applying gene directed enzyme prodrug therapy, and immune activation. New specific target genes and further development of gene technology may bring the break-through in this field.
Wang
Min
M
Department of Biliary and Pancreatic Surgery, the Affiliated Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China. wangmin0501@hotmail.com
Wang
Yi-lin
YL
Lei
Ruo-qing
RQ
Feng
Dian-xu
DX
D000818:Animals; D016147:Genes, Tumor Suppressor; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D007167:Immunotherapy; D010190:Pancreatic Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*