Bromine is an endogenous component of a vanadium bromoperoxidase.
On the basis of EXAFS and MS/MS experimental results and a reinterpretation of the electron density map obtained by X-ray crystallography, we describe a new post-translational modification, that is, a 3,5-dibromotyrosine residue that is incorporated in the polypeptide chain of a vanadium haloperoxidase.
Feiters
Martin C
MC
Department of Organic Chemistry, Institute of Molecules and Materials (IMM), Radboud University Nijmegen, 1 Toernooiveld, NL-6525 ED Nijmegen, The Netherlands.
Leblanc
Catherine
C
Küpper
Frithjof C
FC
Meyer-Klaucke
Wolfram
W
Michel
Gurvan
G
Potin
Philippe
P
D001966:Bromine / Q000378:metabolism*; D010544:Peroxidases / Q000737:chemistry / Q000378:metabolism*; D000459:Phaeophyceae / Q000201:enzymology*; D011499:Protein Processing, Post-Translational; D013057:Spectrum Analysis; D014443:Tyrosine / Q000378:metabolism; D014965:X-Rays
D014443:Tyrosine; D010544:Peroxidases; C026195:bromide peroxidase; D001966:Bromine