Natural phosphate doped with KI in HMDS: a mild and efficient reagent for alkylation and glycosylation of nucleobases.
Several D-ribonucleosides are prepared from 1-O-acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranoside and trimethylsilylated nucleobases under mild conditions by using natural phosphate doped with KI as catalyst.
Lazrek
H B
HB
Faculty of Sciences Semlalia, Marrakech, Morocco.
Taourirte
M
M
Rochdi
A
A
Redwane
N
N
Ouzebla
D
D
Baddi
L
L
Sebti
S
S
Vasseur
J J
JJ
D000478:Alkylation; D002384:Catalysis; D002845:Chromatography; D006027:Glycosides / Q000737:chemistry; D006031:Glycosylation; D006838:Hydrocarbons / Q000737:chemistry; D007202:Indicators and Reagents / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D008956:Models, Chemical; D008967:Molecular Biology / Q000379:methods*; D009705:Nucleosides / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry*; D011193:Potassium Iodide / Q000737:chemistry
D006027:Glycosides; D006838:Hydrocarbons; D007202:Indicators and Reagents; D009705:Nucleosides; D010710:Phosphates; D011193:Potassium Iodide; C030011:carbene; D008697:Methane