title: Novel DNA nanoparticles and networks.
abstract: Joining the thrombin-binding aptamer 5-d(GGTTGGTGTGGTTGG) and the minihairpin 5-d(GCGAAGC) leads to new DNA nanoparticles, which are different from rod-like helical double-stranded DNA. Covalent interstrand cross-links in DNA duplexes generated by bifunctional alkadiyne chains were used to build-up the DNA networks.
authors.affiliation: Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Seela
authors.forename: Anup M
authors.initials: AM
authors.lastname: Jawalekar
authors.forename: Venkata R
authors.initials: VR
authors.lastname: Sirivolu
authors.forename: Helmut
authors.initials: H
authors.lastname: Rosemeyer
authors.forename: Yang
authors.initials: Y
authors.lastname: He
authors.forename: Peter
authors.initials: P
authors.lastname: Leonard
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry; D020029:Base Pairing; D001665:Binding Sites; D015374:Biosensing Techniques; D004247:DNA / Q000737:chemistry*; D018014:Gene Transfer Techniques; D008956:Models, Chemical; D008967:Molecular Biology / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D009690:Nucleic Acid Conformation; D011108:Polymers / Q000737:chemistry; D013696:Temperature; D013816:Thermodynamics; D013917:Thrombin / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D011108:Polymers; C081676:thrombin aptamer; D004247:DNA; D013917:Thrombin