title: Cytotoxic phenylpropanoid glycosides from the stems of Smilax china.
abstract: Bioassay-guided fractionation of an ethanol extract of Smilax china led to the isolation of nine phenylpropanoids including six new compounds, smilasides A-F (1-6), and three known phenylpropanoids, smiglaside E, heloniosides B, and 2',6'-diacetyl-3,6-diferuloylsucrose. Structural elucidation of isolates 1-6 was based on spectroscopic data analysis. These new phenylpropanoids were evaluated against several human tumor cell lines.
authors.affiliation: National Research Institute of Chinese Medicine, Taipei, 112 Taiwan, Republic of China. kuoyh@nricm.edu.tw
authors.forename: Yao-Haur
authors.initials: YH
authors.lastname: Kuo
authors.forename: Ya-Wen
authors.initials: YW
authors.lastname: Hsu
authors.forename: Chia-Ching
authors.initials: CC
authors.lastname: Liaw
authors.forename: Jiun Kuan
authors.initials: JK
authors.lastname: Lee
authors.forename: Hui-Chi
authors.initials: HC
authors.lastname: Huang
authors.forename: Li-Ming Yang
authors.initials: LM
authors.lastname: Kuo
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D020005:Propanols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032281:Smilax / Q000737:chemistry*; D013624:Taiwan; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D006027:Glycosides; D020005:Propanols