title: Effect of opioid antagonist naloxone on maternal motivation in albino rats.
abstract: We studied the effect of nonselective antagonist of opioid receptor naloxone on the behavior of albino female rats on days 4-6 after delivery. Intraperitoneal injection of naloxone (5 mg/kg) significantly stimulated maternal reactions (increased the number of approaches to pups, decreased the latency of their transfer into new location). Intranasal naloxone (1 mg/kg) produced similar changes. Naloxone in intraperitoneal dose of 1 mg/kg and intranasal dose of 0.2 mg/kg virtually did not modify maternal behavior.
authors.affiliation: Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University.
authors.forename: Yu V
authors.initials: YV
authors.lastname: Dobryakova
authors.forename: V A
authors.initials: VA
authors.lastname: Dubynin
authors.forename: Yu A
authors.initials: YA
authors.lastname: Ivleva
authors.forename: Yu A
authors.initials: YA
authors.lastname: Belyaeva
authors.forename: A A
authors.initials: AA
authors.lastname: Kamenskii
mesh_terms: D000818:Animals; D005260:Female; D008425:Maternal Behavior / Q000187:drug effects*; D009042:Motivation; D009270:Naloxone / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D051381:Rats; D011922:Rats, Mutant Strains
chemical_list: D009292:Narcotic Antagonists; D009270:Naloxone