Spectrofluorimetric determination of fendiline in tablets.
A simple, sensitive and accurate spectrofluorimetric method was developed for the assay of fendiline in tablets. Validation of the method provided good results concerning linearity, precision and accuracy. The linearity range was found to be 0.1-0.8 mg/l. The fluorescence intensity was measured at 288 nm for fendiline tablet solutions. It was also found that the excipients in the commercial tablets did not interfere with the method.
Sádecká
J
J
Department of Analytical Chemistry, Faculty of Chemical and Food Technology, Bratislava, Slovakia. jana.sadecka@stuba.sk
Netriová
J
J
D002121:Calcium Channel Blockers / Q000032:analysis*; D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D005079:Excipients; D005275:Fendiline / Q000032:analysis*; D008823:Micelles; D012967:Sodium Dodecyl Sulfate; D012997:Solvents; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D002121:Calcium Channel Blockers; D005079:Excipients; D008823:Micelles; D012997:Solvents; D013607:Tablets; D012967:Sodium Dodecyl Sulfate; D005275:Fendiline