Thrombocytopenia due to cytomegalovirus infection in an immunocompetent adult.
A healthy 33-year-old man presented with a short history of viral infection and recent petechiae. Examination of the blood showed a profound thrombocytopenia. He was diagnosed as having cytomegalovirus infection by serological examination. A high level of platelet-associated immunoglobulins was demonstrated suggesting an immune basis for the thrombocytopenia and we, therefore, treated the patient with bolus methylprednisolone and gamma-globulin, resulting in prompt recovery. Recognition for CMV-induced thrombocytopenia is important for early diagnosis.
Nomura
Kenichi
K
Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kawaramachi Hirokoji, Kyoto, Japan. nomuken@koto.kpu-m.ac.jp
Matsumoto
Yosuke
Y
Kotoura
Yoshihiro
Y
Shimizu
Daisuke
D
Kamitsuji
Yuri
Y
Horiike
Shigeo
S
Tamiwaki
Masafumi
M
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007121:Immunocompetence / Q000187:drug effects; D007074:Immunoglobulin G / Q000008:administration & dosage*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D010976:Platelet Count / Q000379:methods; D013921:Thrombocytopenia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000821:virology
D000893:Anti-Inflammatory Agents; D007074:Immunoglobulin G; D008775:Methylprednisolone