[Neuropsychiatric lupus and lupus nephritis as a clinical manifestations of systemic lupus erythematosus].
Neuropsychiatric (NP) lupus and lupus nephritis are one of the most profound manifestations of the Systemic lupus erythematosus (SLE), with wide variety of clinical manifestations. Especially NP lupus is the most poorly understood subset of the disease, and the most difficult therapeutic problem. We present case report of female SLE patient with the associated difficult and different clinical manifestations of central and peripheral nervous system disease end renal involvement. Agressive treatment option with intermittent pulsed intravenous cyclophosphamide and corticosteroids after the second month of treatment brought to complete remission of nephrotic syndrome. Improving of life-threating clinical manifestations of NP lupus was obtained after six months treatment by this immunosupressive therapy and included intravenous immunoglobulin 400 mg/kg body weight during five days monthly.
Rasić
Senija
S
Institut Za Nefrologiju, Klinicki Centar Univerziteta U Sarajevu.
Dzemidzić
Jasminka
J
Srna
Amira
A
Aganović
Kenana
K
Rebić
Damir
D
Muslimović
Alma
A
D000328:Adult; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D008181:Lupus Nephritis / Q000175:diagnosis*; D020945:Lupus Vasculitis, Central Nervous System / Q000175:diagnosis*