Comparison of the RSV respi-strip with direct fluorescent-antigen detection for diagnosis of respiratory syncytial virus infection in pediatric patients.
The RSV Respi-Strip was compared to the SimulFluor respiratory screen for detecting respiratory syncytial virus in nasopharyngeal aspirates from pediatric patients. Of samples tested, 115/239 (49%) were positive by direct fluorescent-antigen detection. The sensitivity and specificity of the RSV Respi-Strip were 92% (95% confidence interval [CI], 86% to 96%) and 98% (95% CI, 94% to 100%), respectively, with a diagnostic efficiency of 95%.
Gregson
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Calgary Laboratory Services, 9-3535 Research Rd. NW, Calgary, Alberta, Canada T2L 2K8. dan.gregson@cls.ab.ca
Lloyd
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Buchan
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Church
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D000293:Adolescent; D000956:Antigens, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003365:Costs and Cost Analysis; D005069:Evaluation Studies as Topic; D019085:Fluorescent Antibody Technique, Direct / Q000191:economics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009305:Nasopharynx / Q000821:virology; D011934:Reagent Strips / Q000191:economics; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis*; D012136:Respiratory Syncytial Viruses / Q000276:immunology / Q000302:isolation & purification*; D012680:Sensitivity and Specificity
D000956:Antigens, Viral; D011934:Reagent Strips