Idiopathic generalized epilepsies: clinical and electroencephalogram diagnosis and treatment.
This review concentrates on the principles of the clinical and electroencephalogram diagnosis of idiopathic generalized epilepsies and their treatment. The electroclinical variability of the main seizure types is detailed and particular emphasis is placed on the differential diagnosis from other seizures and nonepileptic conditions that is essential for the optimal management of these patients. The authors review the various idiopathic generalized epilepsy subsyndromes and conditions that are included in both the 1989 International League Against Epilepsy classification system and the recently proposed International League Against Epilepsy scheme, but also syndromes and forms that have not been formally recognized. Finally, the authors describe the principles of antiepileptic drug treatment with the old and newer drugs, and their specific indications and contraindications in the various syndromes and seizure types.
Koutroumanidis
Michael
M
Department of Clinical Neurophysiology and Epilepsies, Lambeth Wing, 3rd Floor, St Thomas' Hospital, London SE1 7EH, UK. Michael.Koutroumanidis@gstt.nhs.uk
Bourvari
Georgia
G
Tan
Stella Veronica
SV
D000927:Anticonvulsants / Q000627:therapeutic use*; D004569:Electroencephalography / Q000379:methods*; D004831:Epilepsies, Myoclonic / Q000175:diagnosis / Q000503:physiopathology; D004829:Epilepsy, Generalized / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D005104:Expert Testimony; D006801:Humans
D000927:Anticonvulsants