title: Synthesis of 2-nitro- and 2,2'-dinitrobiphenyls by means of the suzuki cross-coupling reaction.
abstract: [Reaction: see text]. Mechanistic investigations and protocols for the synthesis of 2-nitrobiphenyls and 2,2'-dinitrobiphenyls are disclosed. It is revealed that obstacles appear during the transmetalation step when the phenylboronic acid is substituted with a nitro group in the 2-position, whereas when substituted in the 3- or 4-positions, the reaction follows similar patterns as found in the electrophilic substitution of nitrobenzenes, an observation that may be attributed to the elimination step of the catalytic cycle.
authors.affiliation: Department of Chemistry, University of Bergen, Allégaten 41, N-5007 Bergen, Norway.
authors.forename: Raquel Rodríguez
authors.initials: RR
authors.lastname: González
authors.forename: Lucia
authors.initials: L
authors.lastname: Liguori
authors.forename: Alberto Martinez
authors.initials: AM
authors.lastname: Carrillo
authors.forename: Hans-René
authors.initials: HR
authors.lastname: Bjørsvik