title: Parkinsonism with basal ganglia lesions in a patient with uremia: Evidence of vasogenic edema.
abstract: Parkinsonian syndromes associated with basal ganglia pathology have very rarely been reported in patients with end-stage renal failure. The nature and pathophysiology of the basal ganglia lesion responsible for parkinsonism were unknown. A 48-year-old man who had advanced renal failure developed disturbance of balance and gait and decreased spontaneity. Brain magnetic resonance (MR) imaging disclosed bilateral basal ganglia lesions. By the finding of diffusion-weighted image, the apparent diffusion coefficient map, MR angiography, and SPECT, we suggest that the basal ganglia lesions may be the result of vasogenic edema attributable to focal hyperemia secondary to abnormal dilatation of small vessels.
authors.affiliation: Department of Neurology and Nephrology, College of Medicine, Ajou University, Suwon, South Korea. phisland@chol.net
authors.forename: Phil Hyu
authors.initials: PH
authors.lastname: Lee
authors.forename: Dong Hun
authors.initials: DH
authors.lastname: Shin
authors.forename: Ji Won
authors.initials: JW
authors.lastname: Kim
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Song
authors.forename: Heung Soo
authors.initials: HS
authors.lastname: Kim
mesh_terms: D001929:Brain Edema / Q000150:complications* / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation / Q000502:physiology; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000000981:diagnostic imaging; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015899:Tomography, Emission-Computed, Single-Photon