[Bisphosphonates and combined treatments osteoporosis].
Bisphosphonates are inhibitors of bone resorption, which reduce vertebral and non-vertebral fracture risk. Their efficacity has been shown in controlled trials up to 5 years, and their safety up to ten years. There is no proven benefit of combining two bone resorption inhibitors.
Rizzoli
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R
Centre collaborateur de I'OMS pour la prevention de I'ostéoporose, Service des maladies osseuses, Département de rehabilitation et gériatrie, HUG, 1211 Genève. rene.rizzoli@medecine.unige.ch
Ferrari
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S
D001862:Bone Resorption / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004164:Diphosphonates / Q000494:pharmacology / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy*
D004164:Diphosphonates