Synthesis of novel alpha-L-arabinopyranosides of beta-lactams with potential antimicrobial activity.
Synthetic routes toward the synthesis of some novel 1-(2,3,4-tri-O-acetyl-alpha-L-arabinopyranosyl)-azetidin-2-ones are described. Antimicrobial screening of three selected compounds revealed their activity against Bacillus subtilis and Escherichia coli
Khalil
Nasser S A M
NS
Central Laboratory for Food and Feed, Agricultural Research Center, Giza, Egypt. nasserkhalil_23@hotmail.com
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001089:Arabinose / Q000737:chemistry; D001412:Bacillus subtilis / Q000187:drug effects; D001671:Biochemistry / Q000379:methods*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D047090:beta-Lactams / Q000737:chemistry*
D000890:Anti-Infective Agents; D047090:beta-Lactams; D001089:Arabinose