title: Phenolic glycosides and ionone glycoside from the stem of Sargentodoxa cuneata.
abstract: Four phenolic glycosides, cuneatasides A-D (1-4), and one ionone glycoside cuneataside E (5), together with seven known phenolic compounds (6-12) were isolated from the water-soluble constituents of the stem of Sargentodoxa cuneata (Sargentodoxaceae). Their structures were elucidated by spectroscopic analysis. In vitro tests for antimicrobial activity showed compounds 1 and 2 to possess significant activity against two Gram-positive organisms, Staphylococcus aureus and Micrococcus epidermidis.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA. jch1@uic.edu
authors.forename: Jun
authors.initials: J
authors.lastname: Chang
authors.forename: Ryan
authors.initials: R
authors.lastname: Case
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008837:Micrococcus / Q000187:drug effects; D015394:Molecular Structure; D045792:Norisoprenoids / Q000737:chemistry* / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D029626:Ranunculaceae / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D006027:Glycosides; D045792:Norisoprenoids; D010636:Phenols; C508091:cuneataside A; C508092:cuneataside B