Energy-resolved in-source collisionally induced dissociation for the evaluation of the relative stability of noncovalent complexes in the gas phase.
Energy-resolved in-source collisionally induced dissociation (CID) studies on the complexation of alkali metal cations by some crown ethers, nucleic acid bases, and amino acids have been performed. It has been shown that the cone voltage corresponding to the maximum ion abundance (V(c,Imax)) of the breakdown curve is characteristic of a given ion and not influenced by the cone desolvation process or the composition of the solution. Very good agreement of the V(c,Imax) value with the bond strength of the ion has been observed. Determination of the V(c,Imax) values for different ionic species is a useful, simple, and inexpensive way to obtain their relative stabilities in in-source CID conditions.
Lyapchenko
Nataliya
N
Department of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland. lyapchenko@interia.pl
Schroeder
Grzegorz
G
D000596:Amino Acids / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D043844:Crown Ethers / Q000737:chemistry*; D005240:Feasibility Studies; D008672:Metals, Alkali / Q000737:chemistry*; D009705:Nucleosides / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D000596:Amino Acids; D043844:Crown Ethers; D008672:Metals, Alkali; D009705:Nucleosides