5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)- 1,2-isoxazoline as a useful rice herbicide.
5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1,2-isoxazoline derivative was synthesized, and its herbicidal activity was assessed under glasshouse and flooded paddy conditions. 5-(2,6-Difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1,2-isoxazoline demonstrated good rice selectivity and potent herbicidal activity against annual weeds at 125 g of a.i. ha(-1) under greenhouse conditions. Soil application of this compound showed complete control of barnyard-grass to the fourth leaf stage at 250 g of a.i. ha(-1). Field trials indicated that this compound controlled annual weeds rapidly with a good tolerance on transplanted rice seedlings by post-emergence and soil application. This compound showed a low mammalian and environmental toxicity in various toxicological tests.
Hwang
In Taek
IT
Korea Research Institute of Chemical Technology, Yuseong, Taejon 305-606, Korea. ithwang@krict.re.kr
Kim
Hyoung Rae
HR
Jeon
Dong Ju
DJ
Hong
Kyung Sik
KS
Song
Jong Hwan
JH
Cho
Kwang Yun
KY
D000818:Animals; D006540:Herbicides / Q000008:administration & dosage* / Q000633:toxicity; D007555:Isoxazoles / Q000008:administration & dosage* / Q000633:toxicity; D051379:Mice; D012275:Oryza / Q000187:drug effects / Q000254:growth & development*; D006109:Poaceae / Q000187:drug effects
C506359:5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)- 1,2-isoxazoline; D006540:Herbicides; D007555:Isoxazoles