Counting chromosomes: not as easy as 1, 2, 3.
Mammalian cells must count their X chromosomes to determine whether to initiate X chromosome inactivation. A region that may be important for X chromosome counting has been identified, but the puzzle pieces still do not quite fit.
Alexander
Mary Kate
MK
University of California, San Francisco, Department of Biochemistry and Biophysics, 600 16th Street, Box 2200, San Francisco, California 94158, USA.
Panning
Barbara
B
D000818:Animals; D033481:Chromosomes, Mammalian / Q000235:genetics*; D017353:Gene Deletion; D008322:Mammals / Q000235:genetics*; D008957:Models, Genetic; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated / Q000235:genetics; D019076:Transgenes / Q000235:genetics; D049951:X Chromosome Inactivation / Q000235:genetics / Q000502:physiology*
D062085:RNA, Long Noncoding; D022661:RNA, Untranslated; C077885:XIST non-coding RNA