Zimmermann-Laband syndrome in an infant with an atypical histologic finding.
Zimmermann-Laband syndrome is an inherited disorder that is characterized by abnormalities of the head, face, hands, and feet. Most children with this disorder have generalized hypertrichosis, large gingivae, and hypoplasia of the fingernails and toenails. We report a male infant who exhibited typical features of Zimmermann-Laband syndrome with an unusual histopathologic finding. Excised tissue from the infant's gingivae showed papillary projections that were composed of hyperplastic stratified squamous epithelium with different amounts of keratinization.
Atabek
Mehmet Emre
ME
Department of Pediatrics, Section of Pediatric Endocrinology, School of Medicine, Selcuk University, 42060 Konya, Turkey. meatabek@hotmail.com
Pirgon
Ozgur
O
Sert
Ahmet
A
Toy
Hatice
H
D000015:Abnormalities, Multiple / Q000473:pathology*; D004848:Epithelium / Q000002:abnormalities*; D005881:Gingiva / Q000002:abnormalities*; D006801:Humans; D006983:Hypertrichosis / Q000209:etiology; D007223:Infant; D008297:Male; D008679:Metaplasia / Q000473:pathology; D009264:Nails, Malformed / Q000209:etiology