title: Dissociation between physical and mental number line bisection in right hemisphere brain damage.
abstract: To compare numeric quantities, humans make use of a 'mental number line' with smaller quantities located to the left of larger ones; it is unclear, however, whether orienting along the number line is like orienting along a physical line. We found that in brain-damaged subjects with defective leftward orienting, rightward deviation in the bisection of numeric and physical intervals is doubly dissociated. Deviation in numeric interval bisection was associated with prefrontal damage and spatial working memory deficit.
authors.affiliation: Fondazione Santa Lucia IRCCS - LENA (Laboratoire Europeen Neuroscience de l'Action), Rome, Italy. Fabrizio.Doricchi@uniroma1.it
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Doricchi
authors.forename: Paola
authors.initials: P
authors.lastname: Guariglia
authors.forename: Marina
authors.initials: M
authors.lastname: Gasparini
authors.forename: Francesco
authors.initials: F
authors.lastname: Tomaiuolo
mesh_terms: D001925:Brain Damage, Chronic / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D003072:Cognition Disorders / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008569:Memory Disorders / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D008570:Memory, Short-Term / Q000502:physiology; D008875:Middle Aged; D009415:Nerve Net / Q000473:pathology / Q000503:physiopathology; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D009949:Orientation / Q000502:physiology; D010468:Perceptual Disorders / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D017397:Prefrontal Cortex / Q000473:pathology / Q000503:physiopathology