One circuit, two kinds of timing.
In this issue of Neuron, Gabernet et al. report an elegant series of in vivo and in vitro experiments that dissect a disynaptic circuit dictating the dynamic transition of cortical spiking responses to whisker stimulation from coincidence detection to temporal integration.
Karmarkar
Uma
U
Division of Neurobiology, Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720, USA.
Dan
Yang
Y
D000818:Animals; D051379:Mice; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time; D009435:Synaptic Transmission