[Evaluation of the usefulness of SIS and MS/MS mode for the determination of persistent organochlorine compounds and polychlorinated biphenyls in human specimens].
This study aimed of examining of the applicability of the SIS (Selected Ion Storage) and the MS/ MS (Tandem Mass Spectrometry) methods for analyzing organochlorine pesticide (OCs) residues and PCBs in human specimens. The samples of human abdominal adipose tissue, women's breast adipose tissue, and human milk were used as study material. The samples were analyzed using the gas chromatography method with EC and MS detectors. MS/MS and SIS mode allow to eliminate system-based (e.g., column, septum) ions and the biological samples extract impurities' ions from the background to achieve the analytical system sensitive enough for trace analysis of organochlorine compounds in human specimens.
Hernik
Agnieszka
A
Zakład Toksykologii Srodowiskowej, Państwowy Zakład Higieny, 00-791 Warszawa, ul. Chocimska 24.
Czaja
Katarzyna
K
Góralczyk
Katarzyna
K
Struciński
Paweł
P
Ludwicki
Jan K
JK
D034861:Abdominal Wall; D000273:Adipose Tissue / Q000737:chemistry; D001940:Breast / Q000737:chemistry; D002849:Chromatography, Gas; D004787:Environmental Pollution / Q000009:adverse effects; D005260:Female; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis; D008400:Mass Chest X-Ray; D013058:Mass Spectrometry / Q000379:methods; D008895:Milk, Human / Q000737:chemistry; D010573:Pesticide Residues / Q000032:analysis*; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018629:Spectrometry, Mass, Secondary Ion / Q000379:methods
D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D011078:Polychlorinated Biphenyls