title: Archaeal DNA replication and repair.
abstract: Since the first archaeal genome was sequenced, much attention has been focused on the study of these unique microorganisms. We have learnt that although archaeal DNA metabolic processes (replication, recombination and repair) are more similar to the metabolic processes of Eukarya than those of Bacteria, Archaea are not simply 'mini Eukarya'. They are, in fact, a mosaic of the eukaryal and bacterial systems that also possess archaeal-specific features. Recent biochemical and structural studies of the proteins that participate in archaeal DNA replication and repair have increased our understanding of these processes.
authors.affiliation: University of Maryland Biotechnology Institute, Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, USA. kelman@umbi.umd.edu
authors.forename: Zvi
authors.initials: Z
authors.lastname: Kelman
authors.forename: Malcolm F
authors.initials: MF
authors.lastname: White
mesh_terms: D001105:Archaea / Q000235:genetics* / Q000378:metabolism; D019843:Archaeal Proteins / Q000235:genetics / Q000378:metabolism; D004260:DNA Repair; D004261:DNA Replication; D019641:DNA, Archaeal / Q000235:genetics / Q000378:metabolism*; D018741:Replication Origin
chemical_list: D019843:Archaeal Proteins; D019641:DNA, Archaeal