[Analysis of peri-operative management in 1,510 patients with orthotopic liver transplantation].
OBJECTIVE
To study the clinical factors and treatment that related to early prognosis of patients after orthotopic liver transplantation (OLT), in order to improve peri-operative care and raise the survival rate in patients undergoing this operation.


METHODS
Clinical records of 1,510 patients who had undergone OLT in our center were retrospectively analyzed. Twenty variables in pre-operative, intra-operative or post-operative periods were included, and several risk factors which affected the early prognosis after OLT were screened.


RESULTS
With univariate analysis, the following variables showed significant difference between the survival group and the dead group: acute pathology and chronic health evaluation III (APACHE III) score, volume of transfusion and oxygen delivery (DO(2)) of tissue during operation, incidence of infection, and demand of blood purification.


CONCLUSIONS
During peri-operative periods of OLT, combined therapy should be used, and attention should be paid to the risk factors.
Shen
Zhong-yang
ZY
Tianjin First Central Hospital, Tianjin 300192, China.
Liu
Yi-he
YH
Yu
Li-xin
LX
Wang
Yu
Y
Liu
Lei
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality*; D008875:Middle Aged; D019990:Perioperative Care; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult