title: [Genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty for severe OSAHS].
abstract: OBJECTIVE
  To explore a comprehensive surgical approach of genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty on the treatment of severe obstructive sleep apnea hypopnea syndrome.
  
  
  METHODS
  Eighteen patients with severe OSAHS (RDI > 40)diagnosed by polysomnography. The obstruction in both the oropharynx and the hypopharynx were determined by preoperative physical examination, fiberoptic pharyngolaryngoscopy, cephalometry, and computed tomography of the upper airway. All the cases were given continuous airway pressure via nose,five to seven days before operation and then were performed genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty. The follow up was at least 6 months postoperatively. The Wilcoxon Signed Rank test was used to compare the preoperative and postoperative results by SPSS11.0 for windows.
  
  
  RESULTS
  Postoperative 6-24 months, there were statistically significance in all but BMI between preoperative and postoperative measurement. Mean RDI was reduced from preoperative (63.83 +/- 16.34) to postoperative (21.43 +/- 20. 34), lowest mean oxygen saturation increased from (72.44 +/- 7.07)% to (81.33 +/- 13.32)%. According to criterion at home, the 6-month rate of responder is 83.33%. The severe complications such as fracture of the mandible and injure of apex of inferior anterior teeth did not occurred.
  
  
  CONCLUSIONS
  GAHM plus UPPP is effective surgical approach for patients with severe OSAHS who suffer from oropharyngeal and hypopharyngeal obstruction.
authors.affiliation: Department of Otolaryngology, Affiliated Shanghai Sixth People's Hospital of Shanghai Jiao-tong University, Shanghai, 200233, China. yinshankai@china.com
authors.forename: Shankai
authors.initials: S
authors.lastname: Yin
authors.forename: Hongliang
authors.initials: H
authors.lastname: Yi
authors.forename: Wenying
authors.initials: W
authors.lastname: Lu
authors.forename: Hongmin
authors.initials: H
authors.lastname: Wu
authors.forename: Jian
authors.initials: J
authors.lastname: Guan
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Cao
authors.forename: Ting
authors.initials: T
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D002680:Chin / Q000601:surgery; D002972:Cleft Palate / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010159:Palate / Q000601:surgery*; D010614:Pharynx / Q000601:surgery; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D014059:Tongue / Q000601:surgery*; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery