title: Inflammation 2005 - Seventh World Congress. Respiratory inflammation.
abstract: In this conference, unlike previous conferences in this series, relatively little time was given to new drug therapy approaches for the treatment of inflammation. Instead, the emphasis was on basic mechanisms with a strong bias toward Australian research. The etiology of chronic obstructive pulmonary disease (COPD) and asthma was discussed in detail with an intensive consideration of mechanisms involved in the development of corticosteroid resistance, particularly the role of histone deacetylase. Various rodent model systems for testing potential inhibitors of COPD and asthma were also presented.
authors.affiliation: PLIVA Research Institute Ltd, Prilaz baruna Filipovica 25, Zagreb, Croatia. michael.parnham@pliva.com
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Parnham
mesh_terms: D000305:Adrenal Cortex Hormones / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D017302:Annexins / Q000494:pharmacology / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy; D000077552:Basiliximab; D018849:Controlled Clinical Trials as Topic; D004195:Disease Models, Animal; D004351:Drug Resistance; D015507:Drugs, Investigational / Q000737:chemistry / Q000627:therapeutic use; D006655:Histone Deacetylases / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D008263:Macrophage Migration-Inhibitory Factors / Q000378:metabolism; D051379:Mice; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D051381:Rats; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D012140:Respiratory Tract Diseases / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology
chemical_list: D000305:Adrenal Cortex Hormones; D017302:Annexins; D000911:Antibodies, Monoclonal; D015507:Drugs, Investigational; D008263:Macrophage Migration-Inhibitory Factors; D011993:Recombinant Fusion Proteins; D000077552:Basiliximab; D006655:Histone Deacetylases