Parry-Romberg syndrome in association with anti-dsDNA antibodies: a case report.
Parry-Romberg syndrome (PRS) is a rare and puzzling disorder that is characterized by progressive hemifacial atrophy. It involves mainly some or all tissues of one side of the face. A case of 21-year-old Caucasian man with hemifacial atrophy in the right facial region is reported. Serological studies with anti-single-stranded DNA (anti-ssDNA), anti-double-stranded DNA (anti-dsDNA), anticentromere (ACA) and antinuclear (ANA) antibodies were done. Anti-dsDNA antibodies was found positive, but the others were negative. Rheumatoid factor (RF) was also negative. Since PRS is rare and its association with anti-dsDNA antibodies was not reported before, this case appears to be the first report.
Gonul
M
M
Department of Dermatology, Numune Research and Training Hospital, Ankara, Turkey.
Dogan
B
B
Izci
Y
Y
Varol
G
G
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005150:Facial Hemiatrophy / Q000097:blood*; D006801:Humans; D008297:Male
D000974:Antibodies, Antinuclear