title: High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora.
abstract: The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.
authors.affiliation: Centre de Recherche en Infectiologie de l'Université Laval, CHUQ (Pavillon CHUL), 2705 boul. Laurier, Sainte-Foy, Québec, G1V 4G2, Canada.
authors.forename: M-C
authors.initials: MC
authors.lastname: Domingo
authors.forename: A
authors.initials: A
authors.lastname: Huletsky
authors.forename: R
authors.initials: R
authors.lastname: Giroux
authors.forename: K
authors.initials: K
authors.lastname: Boissinot
authors.forename: F J
authors.initials: FJ
authors.lastname: Picard
authors.forename: P
authors.initials: P
authors.lastname: Lebel
authors.forename: M J
authors.initials: MJ
authors.lastname: Ferraro
authors.forename: M G
authors.initials: MG
authors.lastname: Bergeron
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D004352:Drug Resistance, Microbial / Q000235:genetics*; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D006801:Humans; D010453:Peptide Synthases / Q000235:genetics*; D016133:Polymerase Chain Reaction; D020713:Vancomycin Resistance / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; C079913:VanB protein, Enterococcus; C417270:VanG protein, Enterococcus faecalis; D010453:Peptide Synthases; C122181:VanD protein, Enterococcus faecium