title: Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: the appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results.
abstract: The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry.
authors.affiliation: Department of Radiation Oncology, Chang Gung Memorial Hospital-Kaohsiung, Kaohsiung Hsien, Taiwan, ROC. hsiungcy@hotmail.com
authors.forename: Ching-Yeh
authors.initials: CY
authors.lastname: Hsiung
authors.forename: Margie A
authors.initials: MA
authors.lastname: Hunt
authors.forename: Ellen D
authors.initials: ED
authors.lastname: Yorke
authors.forename: Chen-Shou
authors.initials: CS
authors.lastname: Chui
authors.forename: Jason
authors.initials: J
authors.lastname: Hu
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Xiong
authors.forename: Clifton C
authors.initials: CC
authors.lastname: Ling
authors.forename: Sing-Kai
authors.initials: SK
authors.lastname: Lo
authors.forename: Chong-Jong
authors.initials: CJ
authors.lastname: Wang
authors.forename: Eng-Yen
authors.initials: EY
authors.lastname: Huang
authors.forename: Howard I
authors.initials: HI
authors.lastname: Amols
mesh_terms: D002277:Carcinoma / Q000532:radiotherapy*; D019583:Dose Fractionation, Radiation; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D011379:Prognosis; D011832:Radiation Injuries / Q000209:etiology* / Q000517:prevention & control*; D020266:Radiotherapy, Conformal / Q000379:methods*; D016879:Salvage Therapy