title: Age as a determinant of nutritional status: a cross sectional study.
abstract: BACKGROUND
  Undenutrition is known to be prevalent and largely unrecognised in older patients; however, aberrations in indicators of nutritional status may simply reflect effects of age and/or functional disability.
  
  
  OBJECTIVE
  The aim of this study was to measure the effect, if any of age on nutritional status in older patients.
  
  
  METHODS
  445 randomly selected hospitalised patients consented to nutritional status assessment derived from anthropometric, haematological, and biochemical data within 72 hours of admission. Nutritional status was compared between those age < 75 years and those aged 75 years or more. Using multiple regression models, we measured the association between age and nutritional assessment variables after adjusting for disability, chronic illness, medications, smoking and tissue inflammation.
  
  
  RESULTS
  Body weight, body mass index, mid-upper arm circumference, haemoglobin, serum albumin and plasma ascorbic acid were all significantly lower in people aged > or = 75 years compared with those < 75 years of age. Although riboflavin (vitamin B2), 25OH VitD3, red-cell folate and vitamin B12 concentrations were lower in those aged > or = 75 years, differences were not statistically significant. After adjusting for disability and co-morbidity in a multivariate analysis, age alone had a significant and independent effect on important anthropometric and biochemical nutritional assessment variables.
  
  
  CONCLUSIONS
  Increasing age is independently associated with poor nutritional status. This may partly explain the poor clinical outcome in older patients.
authors.affiliation: Sheffield Institute for Studies on Ageing, The University of Sheffield & Barnsley Hospital, Northern General Hospital, Sheffield, S5 7AU, UK. s.f.forster@sheffield.ac.uk
authors.forename: Sarah
authors.initials: S
authors.lastname: Forster
authors.forename: Salah
authors.initials: S
authors.lastname: Gariballa
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D000886:Anthropometry; D001205:Ascorbic Acid / Q000097:blood; D015992:Body Mass Index; D001835:Body Weight; D002112:Calcifediol / Q000097:blood; D003430:Cross-Sectional Studies; D004912:Erythrocytes / Q000737:chemistry; D005492:Folic Acid / Q000097:blood; D006304:Health Status; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015596:Nutrition Assessment; D009752:Nutritional Status / Q000502:physiology*; D012044:Regression Analysis; D012256:Riboflavin / Q000097:blood; D012709:Serum Albumin / Q000032:analysis; D014805:Vitamin B 12 / Q000097:blood
chemical_list: D006454:Hemoglobins; D012709:Serum Albumin; D005492:Folic Acid; D014805:Vitamin B 12; D002112:Calcifediol; D001205:Ascorbic Acid; D012256:Riboflavin