title: Utility of magnetic resonance imaging for distinguishing neoplastic from non-neoplastic brain lesions in dogs and cats.
abstract: The aim of this study was to identify magnetic resonance (MR) signs that aid differentiation of neoplastic vs. non-neoplastic brain diseases in dogs and cats. MR images of 36 dogs and 13 cats with histologic diagnosis of intracranial disease were reviewed retrospectively. Diagnoses included 30 primary and three metastatic brain tumors, 11 infectious/inflammatory lesions, three vascular, one degenerative disease, and one developmental malformation. Upon univariate analysis of 21 MR signs, there were seven that had a significant association with neoplasia: single lesion (P = 0.004), shape (P = 0.015), mass effect (P = 0.002), dural contact (P = 0.04), dural tail (P = 0.005), lesions affecting adjacent bone (P = 0.008), and contrast enhancement (P = 0.025). Increasing age was also found to be associated with neoplasia (P = 0.0001). MR signs of non-neoplastic brain diseases in dogs and cats were more variable than those of brain neoplasia.
authors.affiliation: Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, UK. gbcherubini@rvc.ac.uk
authors.forename: Giunio Bruto
authors.initials: GB
authors.lastname: Cherubini
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Mantis
authors.forename: Teresa A
authors.initials: TA
authors.lastname: Martinez
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Lamb
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Cappello
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D003287:Contrast Media; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D011237:Predictive Value of Tests; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media