title: Functional recovery after hemiplegia in patients with neglect: the rehabilitative role of anosognosia.
abstract: OBJECTIVE
  The aim of this study was to verify whether the presence of anosognosia (A) affects the rehabilitative prognosis of hemiplegic subjects with neglect (N).
  
  
  METHODS
  This study was carried out on 30 patients with left hemiplegia: 15 patients had neglect (group N) and 15 had neglect and anosognosia (group N+A). Mean age was 68.2+/-6.3 in group N (9 men and 6 women) and 72.1+/-6.4 in group N+A (7 men and 8 women). The average interval from onset of stroke to admission for rehabilitation was 23 and 23.6 days, respectively, in group N and in group N+A. Patients were assessed through the Mesulam test, Bisiach test, Wechsler Adult Intelligence Scale, Fugl-Meyer scale, Functional Independence Measure (FIM), and Rankin scale.
  
  
  RESULTS
  Before rehabilitation, cognitive FIM scores of patients of group N were significantly higher than those of group N+A (P=0.001), whereas motor FIM scores and total FIM scores did not differ between the 2 groups. After rehabilitation, cognitive FIM scores (P=0.000) and even motor (P=0.009) and total FIM scores (P=0.000) were statistically higher in group N than in group N+A. Effectiveness (P=0.005) and efficiency (P=0.012) in the motor FIM scores of group N were significantly greater than those of group N+A. Disability was lower in group N (P=0.040).
  
  
  CONCLUSIONS
  Our study shows that the presence of anosognosia worsens the rehabilitation prognosis in hemiplegic subjects who also have neglect.
authors.affiliation: Rehabilitation Department, Salvatore Maugeri Foundation, Istituto di Ricovero e Cura a Carattere Scientifico-Scientific Institute of Gussago/Lumezzane, Gussago, Italy. bgialanella@fsm.it
authors.forename: Bernardo
authors.initials: B
authors.lastname: Gialanella
authors.forename: Vittoria
authors.initials: V
authors.lastname: Monguzzi
authors.forename: Raffaele
authors.initials: R
authors.lastname: Santoro
authors.forename: Silvana
authors.initials: S
authors.lastname: Rocchi
mesh_terms: D000368:Aged; D002544:Cerebral Infarction / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D006429:Hemiplegia / Q000150:complications* / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D009048:Motor Skills / Q000145:classification; D019957:Motor Skills Disorders / Q000145:classification / Q000209:etiology / Q000534:rehabilitation; D010468:Perceptual Disorders / Q000150:complications*; D011379:Prognosis; D020127:Recovery of Function; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome