Ca(2+) transport into sarcoplasmic reticulum and immediate-early response proteins in the myocardium of rats resuscitated after systemic circulatory arrest.
Activity of antioxidant defense enzymes and content of stress protein HSP70 in the heart increased in passive and, to a lesser extent, in active rats on day 7 of the postresuscitation period after systemic circulatory arrest. The resistance of membrane structures in the heart to endogenous damaging factors in passive rats was lower than in active animals. The degree of compensation in active rats was much higher than in passive animals at these terms of the postresuscitation period.
Sazontova
T G
TG
Department of Fundamental Medicine, M. V. Lomonosov Moscow State University, Moscow. arkhipenko@fbm.msu.ru
Zhukova
A G
AG
Zarzhetskii
Yu V
YV
Avrushchenko
M Sh
MSh
Volkov
A V
AV
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D015153:Blotting, Western; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D018840:HSP70 Heat-Shock Proteins / Q000378:metabolism*; D017874:Immediate-Early Proteins / Q000378:metabolism*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D011922:Rats, Mutant Strains; D012151:Resuscitation; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*; D012769:Shock / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors
D018840:HSP70 Heat-Shock Proteins; D017874:Immediate-Early Proteins; D002374:Catalase; D013482:Superoxide Dismutase; D000252:Calcium-Transporting ATPases