A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad.
The chemical synthesis of bunch-ODN I and II prone to form quadruplex structures containing G-and T-tetrads has been reported. Structural studies were performed by 1H-NMR and CD melting experiments.
Borbone
Nicola
N
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Napoli, Italy. borbone@unina.it
Oliviero
Giorgia
G
Galeone
Aldo
A
Piccialli
Gennaro
G
Varra
Michela
M
Mayol
Luciano
L
D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D009841:Oligonucleotides / Q000737:chemistry*; D013696:Temperature
D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D004247:DNA