title: An evaluation of bilateral monitoring of cerebral oxygen saturation during pediatric cardiac surgery.
abstract: Cerebral oximetry is a technique that enables monitoring of regional cerebral oxygenation during cardiac surgery. In this study, we evaluated differences in bi-hemispheric measurement of cerebral oxygen saturation using near-infrared spectroscopy in 62 infants undergoing biventricular repair without aortic arch reconstruction. Left and right regional cerebral oxygen saturation index (rSO2i) were recorded continuously after the induction of anesthesia, and data were analyzed at 12 time points. Baseline rSO2i measurements were left 65 +/- 13 and right 66 +/- 13 (P = 0.17). Mean left and right rSO2i measurements were similar (< or =2 percentage points/absolute scale units) before, during, and after cardiopulmonary bypass, irrespective of the use of deep hypothermic circulatory arrest. Further longitudinal neurological outcome studies are required to determine whether uni- or bi-hemispheric monitoring is required in this patient population.
authors.affiliation: Departments of *Anesthesiology, Perioperative, and Pain Medicine, †Clinical Research Program, ‡Cardiology and §Cardiovascular Surgery, Children's Hospital Boston; Departments of ∥Anesthesia, ¶Cardiology, #Pediatrics, and **Surgery, Harvard Medical School; and ††Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts.
authors.forename: Barry D
authors.initials: BD
authors.lastname: Kussman
authors.forename: David
authors.initials: D
authors.lastname: Wypij
authors.forename: James A
authors.initials: JA
authors.lastname: DiNardo
authors.forename: Jane
authors.initials: J
authors.lastname: Newburger
authors.forename: Richard A
authors.initials: RA
authors.lastname: Jonas
authors.forename: Jodi
authors.initials: J
authors.lastname: Bartlett
authors.forename: Ellen
authors.initials: E
authors.lastname: McGrath
authors.forename: Peter C
authors.initials: PC
authors.lastname: Laussen
mesh_terms: D001921:Brain / Q000378:metabolism*; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002648:Child; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000378:metabolism*
chemical_list: D010100:Oxygen