A new method for evaluation of radioactive label transport intensity in the predominant direction between blood and liver.
The intensity of (75)Se transport in the predominant direction after intraperitoneal injection of [(75)Se]selenate was compared in 1- and 3-month-old rats receiving common vivarium ration or sucrose diet. The incorporation percent, blood/liver relative radioactivity, and relative radioactivity difference coefficient were evaluated in the blood and liver. The dynamics of label incorporation in the blood of rats fed common diets has two peaks (at 1-3 h and 12-24 h) and a drop at 6 h. Coefficient of difference in 1-month-old rats was characterized by a greater amplitude of fluctuations than in 3-month-old animals.
Petrovich
Yu A
YA
Moscow State Medical Stomatological University.
Podorozhnaya
R P
RP
Kichenko
S M
SM
D000367:Age Factors; D000818:Animals; D001692:Biological Transport / Q000502:physiology; D008099:Liver / Q000378:metabolism*; D051381:Rats; D012644:Selenium Radioisotopes / Q000097:blood* / Q000378:metabolism / Q000493:pharmacokinetics*; D013997:Time Factors
D012644:Selenium Radioisotopes