title: Synthesis of 2'-C-methyl-4'-thio ribonucleosides.
abstract: Starting from 2-C-methyl-ribonolactone, 1,2,3,5-tetra-O-acetyl-2-C-methyl-4-thioribofuranose was synthesized and condensed with heterocyclic bases to afford 2-C-methyl-4'-thioribonucleosides.
authors.affiliation: Laboratoire Coopératif Idenix-CNRS, Université Montpellier II, Montpellier Cedex 5, France.
authors.forename: D
authors.initials: D
authors.lastname: Dukhan
authors.forename: E
authors.initials: E
authors.lastname: Bosc
authors.forename: J
authors.initials: J
authors.lastname: Peyronnet
authors.forename: R
authors.initials: R
authors.lastname: Storer
authors.forename: G
authors.initials: G
authors.lastname: Gosselin
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D008956:Models, Chemical; D009705:Nucleosides / Q000737:chemistry; D012328:RNA Viruses / Q000235:genetics; D013872:Thionucleosides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D009705:Nucleosides; D013872:Thionucleosides; D003841:Deoxycytidine; C055031:2'-methyl-2'-deoxycytidine