[Chronic EBV-infection in children with a high level of anti-H+/K+-ATPhase antibodies in gastric parietal].
We examined 50 children at the age of 4-17 suffering from chronic gastritis. AntiH+/K+-ATPhase antibodies of gastric parietal cells, anti-EBV antibodies IgG EA and IgM VCA were determined with the help of immune-enzyme analysis methods. The first group comprised 28 children with a high level of antiparietal antibodies in the blood serum, and 22 children with a normal level of antiparietal antibodies made up the second group. The HP identification was carried out for all children. Anti-EBV antibodies IgG EA were found in 72% of children, and there were no statistical differences in the frequency and level of antibodies IgG EA. IgM VCA were not found in any of the patients. However, HP-infection was revealed in 64.3% in the first group vs. 22.7% in the second group (p < 0,05); the combination of HB and chronic EBV infection was also more frequent in the first group than in the second group (42.8% and 18.1%, respectively, p < 0,05).
Tkachenko
E I
EI
Novikova
V P
VP
Abdul Satar
Sh
Sh
Aksenov
O A
OA
Mikheeva
E A
EA
Goncharova
L B
LB
Iur'ev
V V
VV
Evstratov
Iu S
IuS
D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000276:immunology; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005756:Gastritis / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D017506:H(+)-K(+)-Exchanging ATPase / Q000276:immunology*; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D010295:Parietal Cells, Gastric / Q000201:enzymology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D001323:Autoantibodies; C033305:Epstein-Barr virus early antigen; D017506:H(+)-K(+)-Exchanging ATPase