title: Remission of severe antiphospholipid syndrome associated with non-Hodgkin's B-cell lymphoma after combined treatment with rituximab and chemotherapy.
abstract: The association of lymphoid neoplasms and antiphospolipid antibodies (APA), with or without thromboembolic complications, has been reported in several cases. We describe one case of B-cell non-Hodgkinís lymphoma (NHL) in which the combination of rituximab with standard chemotherapy led to the complete remission of a severe hypercoagulable state associated with APA.
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale, Sezione di Ematologia, Università di Verona, Italy. dino.veneri@univr.it
authors.forename: Dino
authors.initials: D
authors.lastname: Veneri
authors.forename: Achille
authors.initials: A
authors.lastname: Ambrosetti
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Federico
authors.initials: F
authors.lastname: Mosna
authors.forename: Giovanni
authors.initials: G
authors.lastname: Poli
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pizzolo
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D058846:Antibodies, Monoclonal, Murine-Derived; D000925:Anticoagulants / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000209:etiology*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D016393:Lymphoma, B-Cell / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000209:etiology; D012008:Recurrence; D012074:Remission Induction; D000069283:Rituximab; D013156:Splenectomy; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology*; D013924:Thrombophlebitis / Q000188:drug therapy / Q000209:etiology; D014750:Vincristine / Q000008:administration & dosage; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000925:Anticoagulants; D000069283:Rituximab; D014750:Vincristine; D014859:Warfarin; D004317:Doxorubicin; D003520:Cyclophosphamide; D006493:Heparin; D011241:Prednisone