Chemically functionalized water soluble single-walled carbon nanotubes modulate neurite outgrowth.
We report the use of chemically-functionalized water soluble single-walled carbon nanotube (SWNT) graft copolymers for modulation of outgrowth of neuronal processes. The graft copolymers were prepared by the functionalization of SWNTs with poly-m-aminobenzene sulphonic acid and polyethylene glycol. When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes.
Ni
Yingchun
Y
Department of Cell Biology and Neuroscience, Center for Nanoscale Science and Engineering, University of California, Riverside, CA 92521, USA.
Hu
Hui
H
Malarkey
Erik B
EB
Zhao
Bin
B
Montana
Vedrana
V
Haddon
Robert C
RC
Parpura
Vladimir
V
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D018929:Cell Culture Techniques / Q000379:methods*; D049108:Cell Enlargement; D002478:Cells, Cultured; D003460:Crystallization / Q000379:methods; D003470:Culture Media / Q000737:chemistry; D006624:Hippocampus / Q000166:cytology / Q000502:physiology; D008422:Materials Testing; D036103:Nanotechnology / Q000379:methods*; D037742:Nanotubes, Carbon / Q000032:analysis / Q000737:chemistry* / Q000648:ultrastructure; D016501:Neurites / Q000502:physiology* / Q000648:ultrastructure; D009474:Neurons / Q000166:cytology* / Q000502:physiology*; D010316:Particle Size; D051381:Rats; D017207:Rats, Sprague-Dawley; D012995:Solubility; D013499:Surface Properties; D014867:Water / Q000737:chemistry
D001672:Biocompatible Materials; D003470:Culture Media; D037742:Nanotubes, Carbon; D014867:Water