title: Possible role of Helicobacter pylori in the etiopathogenesis of chronic otitis media.
abstract: OBJECTIVE
  To investigate a possible contribution from Helicobacter pylori to the etiopathogenesis of chronic otitis media.
  
  
  METHODS
  Prospective clinical trial.
  
  
  METHODS
  Tympanomastoidectomy, radical mastoidectomy, and modified radical mastoidectomy procedures were performed according to the pathology of ear disease. Biopsy specimens were taken from middle ear, mastoid antrum, and tympanic orifice of eustachian tube. Helicobacter pylori DNA was extracted from these biopsy specimens by using nested polymerase chain reaction.
  
  
  RESULTS
  Helicobacter pylori DNA was detected in 3 (7.9%) of 38 chronic otitis media patients.
  
  
  CONCLUSIONS
  Even though it is possible to detect Helicobacter pylori in middle ear cleft in chronic otitis media, its role in the etiopathogenesis of the issue is controversial.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, Yüzüncü Yil University, Van, Turkey. ahkutluhan@hotmail.com
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kutluhan
authors.forename: Veysel
authors.initials: V
authors.lastname: Yurttaş
authors.forename: Ulus Salih
authors.initials: US
authors.lastname: Akarca
authors.forename: Ahmet
authors.initials: A
authors.lastname: Aydn
authors.forename: Ilyas
authors.initials: I
authors.lastname: Tuncer
authors.forename: Serdar
authors.initials: S
authors.lastname: Uğraş
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D002908:Chronic Disease; D004432:Ear, Middle / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008416:Mastoid / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010033:Otitis Media / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D016133:Polymerase Chain Reaction