title: Primary duodenal diffuse large cell non-hodgkin lymphoma with involvement of ampulla of Vater: report of 3 cases.
abstract: Primary gastrointestinal system lymphomas constitute about one third of all extranodal lymphomas. Duodenal involvement of the lymphoma is a rare condition. Periampullary lymphoma or lymphomatous involvement of ampulla of Vater is even rarer. Since, periampullary lymphoma is not easy to differentiate from epithelial carcinoma of these sites clinically and radiologically, accurate histopathological diagnosis is essential to plan optimal treatment strategy. Obstructive jaundice and the need for some form of drainage procedure and dose modification of the chemotherapy are additional challenges. In this report, we present three cases of duodenal diffuse large cell lymphoma with involvement of ampulla of Vater, two of whom presented with the initial signs of obstructive jaundice. One of the icteric patients was only diagnosed histopathologically following an explorative laparotomy with the initial diagnosis of carcinoma.
authors.affiliation: Ankara Numune Egitim ve Arastirma Hastanesi, Department of Medical Oncology, Ankara, Turkey.
authors.forename: Nuriye
authors.initials: N
authors.lastname: Yildirim
authors.forename: Berna
authors.initials: B
authors.lastname: Oksüzoğlu
authors.forename: Burçin
authors.initials: B
authors.lastname: Budakoğlu
authors.forename: Murat
authors.initials: M
authors.lastname: Vural
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Abali
authors.forename: Doğan
authors.initials: D
authors.lastname: Uncu
authors.forename: Nurullah
authors.initials: N
authors.lastname: Zengin
mesh_terms: D000328:Adult; D014670:Ampulla of Vater / Q000000981:diagnostic imaging / Q000473:pathology*; D003138:Common Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D041781:Jaundice, Obstructive / Q000000981:diagnostic imaging / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011859:Radiography