title: [Intracavitary application of silics for the treatment of inflammatory-purulent processes].
abstract: The results of clinical application of Silics--new sorbent of polydirected action, based on highly disperse amorphous silica, were presented. Silics owes unique properties, which are manifested while its intracavitary application for treatment of inflammatory-purulent processes. Osmotic activity of sorbent is more than 500%, waterabsorbability--up to 1000%, it sorbates up to 800 mg/g of proteins, microorganisms--up to 10(10) of the colony forming units on 1 g. Silics promotes lysis of necrotized tissues. In clinical application of Silics in 146 patients with retroperitoneal space phlegmon in an acute destructive pancreatitis, in 23--with abdominal cavity abscess, in 34--with inflammatory-purulent pleuropulmonary diseases it was established, that this preparation promotes the intoxication severity lowering, the reduction of microbal sowing of purulent cavities and resistance of the wound microflora to antibotics. The securing of fragmentation of necrotized tissues and the fibrin deposits, lowering of the exudate viscosity rises efficacy of the inflammatory focus drainage. Application of Silics for the treatment of inflammatory-purulent processes permits to improve essentially its results on the account of lowering of mortality and the treatment cost, and the shortage of the patients stationary treatment.
authors.forename: O I
authors.initials: OI
authors.lastname: Bondarchuk
mesh_terms: D018784:Abdominal Abscess / Q000628:therapy*; D000208:Acute Disease; D003646:Debridement; D004322:Drainage; D006801:Humans; D010195:Pancreatitis / Q000628:therapy*; D012140:Respiratory Tract Diseases / Q000628:therapy*; D012187:Retroperitoneal Space; D012822:Silicon Dioxide / Q000008:administration & dosage*; D016060:Sorption Detoxification / Q000379:methods*; D013492:Suppuration; D016896:Treatment Outcome
chemical_list: D012822:Silicon Dioxide