Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine.
The synthesis and preliminary structural studies of ODNs A8MeGGGT and TA8MeGGGT, where A8Me represents 2'-deoxy-8-methyladenosine, are reported.
Randazzo
Antonio
A
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Napoli, Italy.
Esposito
Veronica
V
Galeone
Aldo
A
Varra
Michela
M
Virgilio
Antonella
A
Mayol
Luciano
L
D000241:Adenosine / Q000138:chemical synthesis / Q000737:chemistry*; D002942:Circular Dichroism; D003839:Deoxyadenosines / Q000138:chemical synthesis* / Q000737:chemistry; D006358:Hot Temperature; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*; D013696:Temperature
C502472:8-methyl-2'-deoxyadenosine; D003839:Deoxyadenosines; D009841:Oligonucleotides; D000241:Adenosine