title: Broth microdilution susceptibility testing of Brucella species: quality control limits for ten antimicrobial agents against three standard quality control strains.
abstract: Brucella broth without supplementation is the recommended medium for broth microdilution susceptibility tests of Brucella abortus, B. melitensis, and B. suis. Based on an eight-laboratory collaborative study using a pH-adjusted modification of this medium, we propose MIC quality control ranges for three control strains against 10 antimicrobials that are potentially efficacious for treating infections caused by these agents of bioterrorism.
authors.affiliation: Clinical Microbiology Institute, 9725 S.W. Commerce Circle, Suite A1, Wilsonville, OR 97070, USA. SBrown@clinmicroinst.com
authors.forename: Steven D
authors.initials: SD
authors.lastname: Brown
authors.forename: Maria M
authors.initials: MM
authors.lastname: Traczewski
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D023482:Bioterrorism; D002002:Brucella / Q000187:drug effects* / Q000254:growth & development; D003470:Culture Media; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests / Q000379:methods*; D011786:Quality Control
chemical_list: D000890:Anti-Infective Agents; D003470:Culture Media