title: [Genetic polymorphism analysis of 6 STR loci on the X chromosome in Xi'an Han population].
abstract: OBJECTIVE
  To investigate the alleles and genotypes frequency of 6 short tandem repeat (STR) loci (DXS8378, DXS7132, DXS6789, DXS101, HPRTB and DXS7423) on the X chromosome in Han population.
  
  
  METHODS
  The six X-chromosome STR loci were analyzed by PCR following polyacylamide gel electrophoresis and silver stain.
  
  
  RESULTS
  Among 120 females from Xi'an Han population, the number of alleles in the 6 loci (DXS8378, DXS7132, DXS6789, DXS101, HPRTB and DXS7423) were 5, 6, 11, 10, 8, and 4 respectively; the number of genotypes in the 6 loci were 10, 17, 29, 32, 22, and 7 respectively; Exact tests demonstrated genotype frequencies in females had no departure from Hardy-Weinberg equilibrium.
  
  
  CONCLUSIONS
  The six X-chromosome STR loci are appropriate for individual identification, paternity testing involving a female child and for study on related disease.
authors.affiliation: The National laboratory of the Ministry of Health for Forensic Science, College of Medicine, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Yu
authors.forename: Qun-xia
authors.initials: QX
authors.lastname: Qin
authors.forename: Jin-cheng
authors.initials: JC
authors.lastname: Yan
mesh_terms: D000483:Alleles; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences