Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis.
In a phase 2 open-label, dose-ranging study in patients with candidemia, anidulafungin was effective in eradicating Candida albicans and other species of Candida. The anidulafungin MIC distribution showed that Candida albicans and C. glabrata were the most susceptible species and C. parapsilosis was the least susceptible species.
Pfaller
M A
MA
Medical Microbiology Division, C606 GH, Department of Pathology, Roy J. and A. Carver College of Medicine, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA. michael-pfaller@uiowa.edu
Diekema
D J
DJ
Boyken
L
L
Messer
S A
SA
Tendolkar
S
S
Hollis
R J
RJ
Goldstein
B P
BP
D000328:Adult; D000077612:Anidulafungin; D000935:Antifungal Agents / Q000627:therapeutic use*; D002175:Candida / Q000187:drug effects; D002177:Candidiasis / Q000188:drug therapy*; D054714:Echinocandins; D006801:Humans; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000627:therapeutic use*
D000935:Antifungal Agents; D054714:Echinocandins; D010456:Peptides, Cyclic; D000077612:Anidulafungin