title: Detection of volatile metabolites produced by bacterial growth in blood culture media by selected ion flow tube mass spectrometry (SIFT-MS).
abstract: To achieve faster bacteremia diagnosis, selected ion flow tube mass spectrometry (SIFT-MS) measured metabolic gases in the headspaces of BacT/ALERT blood culture bottles. Pseudomonas aeruginosa, Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and Neisseria meningitidis growth and trace gas patterns were detected from 10 colony forming units after 6 h.
authors.affiliation: Department of Surgery, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand. randall.allardyce@chmeds.ac.nz
authors.forename: Randall A
authors.initials: RA
authors.lastname: Allardyce
authors.forename: Vaughan S
authors.initials: VS
authors.lastname: Langford
authors.forename: Alex L
authors.initials: AL
authors.lastname: Hill
authors.forename: David R
authors.initials: DR
authors.lastname: Murdoch
mesh_terms: D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology; D001419:Bacteria / Q000254:growth & development* / Q000378:metabolism*; D001431:Bacteriological Techniques / Q000295:instrumentation / Q000379:methods; D001769:Blood / Q000382:microbiology; D003470:Culture Media; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D009930:Organic Chemicals / Q000032:analysis*; D014835:Volatilization
chemical_list: D003470:Culture Media; D009930:Organic Chemicals