Splenic autotransplantation for treatment of portal hypertension.
BACKGROUND
When total splenectomy is unavoidable it is important to preserve splenic function in some form in order to prevent the complications of asplenism. Splenic autotransplantation is a good alternative in such cases. We describe the use of splenic autotransplantation for the treatment of portal hypertension.


METHODS
We carried out total splenectomy on 31 patients (21 men, 10 women), ranging in age from 21 to 68 years, with schistosomal portal hypertension. From each removed spleen, we took 20 fragments and implanted them on the greater omentum. This procedure was combined with abdominal portal-variceal disconnection. Transgastric running suture of the lower esophageal and gastric varices completed the treatment of portal hypertension. All patients underwent clinical, hematologic, immunologic and scintigraphic assessment. The results with respect to morbidity and mortality, and hematologic and immunologic findings were compared with those in 36 patients submitted to other splenic procedures.


RESULTS
There was no complication related to the splenic implants and none of the patients died. Hematologic and immunologic findings were normal. Scintigraphy registered images of splenic tissue in all cases.


CONCLUSIONS
The implantation of splenic fragments on the greater omentum seems to be a safe and useful procedure for maintaining splenic function after total splenectomy.
Petroianu
Andy
A
Alfa Institute of Gastroenterology, Hospital of Clinics, Federal University of Minas Gerais, Brazil. petroian@medicina.ufmg.br
Petroianu
Larissa P G
LP
D000328:Adult; D000368:Aged; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009852:Omentum / Q000601:surgery; D012555:Schistosomiasis mansoni / Q000150:complications; D013154:Spleen / Q000637:transplantation*; D014182:Transplantation, Autologous