Sclerotherapy of benign oral vascular lesion with ethanolamine oleate: an open clinical trial with 30 lesions.
OBJECTIVE
The objective of this study was to report and discuss the results from treatment of benign oral vascular lesions with ethanolamine oleate.


METHODS
Twenty-seven patients with 30 examples of oral vascular malformation, hemangioma, or varix were treated with intralesional injections of 1.25% or 2.5% ethanolamine oleate at an interval of 15 days between each application. The lesions were divided into 2 categories: (1) lesions of 20 mm or less and (2) those greater than 20 mm. Subsequently, the Mann-Whitney test was used a means of statistical analysis.


RESULTS
Although the number of injections varied from patient to patient, all lesions responded to the treatment, showing total clinical regression. Lesions of 20 mm or less needed a lesser number of applications than those greater than 20 mm (P < .05).


CONCLUSIONS
Ethanolamine oleate is a 100% effective sclerosant agent for treatment of benign oral vascular lesions. In this study, no difference was found between the 2 concentrations applied.
Johann
Aline Cristina Batista Rodrigues
AC
Department of Oral Surgery and Pathology, School of Dentistry, Federal University of the Minas Gerais, Minas Gerais, Brazil.
Aguiar
Maria Cássia Ferreira
MC
do Carmo
Maria Auxiliadora Vieira
MA
Gomez
Ricardo Santiago
RS
Castro
Wagner Henriques
WH
Mesquita
Ricardo Alves
RA
D000293:Adolescent; D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000628:therapy; D002648:Child; D005260:Female; D006391:Hemangioma / Q000628:therapy; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000628:therapy*; D009062:Mouth Neoplasms / Q000628:therapy*; D009383:Neoplasms, Vascular Tissue / Q000628:therapy*; D009829:Oleic Acids / Q000008:administration & dosage*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D015911:Sclerotherapy; D018709:Statistics, Nonparametric; D014648:Varicose Veins / Q000628:therapy; D014652:Vascular Diseases / Q000628:therapy*
D009829:Oleic Acids; D012597:Sclerosing Solutions; C033343:ethanolamine oleate