[Genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty for severe OSAHS].
OBJECTIVE
To explore a comprehensive surgical approach of genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty on the treatment of severe obstructive sleep apnea hypopnea syndrome.


METHODS
Eighteen patients with severe OSAHS (RDI > 40)diagnosed by polysomnography. The obstruction in both the oropharynx and the hypopharynx were determined by preoperative physical examination, fiberoptic pharyngolaryngoscopy, cephalometry, and computed tomography of the upper airway. All the cases were given continuous airway pressure via nose,five to seven days before operation and then were performed genioglossus advancement and hyoid suspension plus uvulopalatopharyngoplasty. The follow up was at least 6 months postoperatively. The Wilcoxon Signed Rank test was used to compare the preoperative and postoperative results by SPSS11.0 for windows.


RESULTS
Postoperative 6-24 months, there were statistically significance in all but BMI between preoperative and postoperative measurement. Mean RDI was reduced from preoperative (63.83 +/- 16.34) to postoperative (21.43 +/- 20. 34), lowest mean oxygen saturation increased from (72.44 +/- 7.07)% to (81.33 +/- 13.32)%. According to criterion at home, the 6-month rate of responder is 83.33%. The severe complications such as fracture of the mandible and injure of apex of inferior anterior teeth did not occurred.


CONCLUSIONS
GAHM plus UPPP is effective surgical approach for patients with severe OSAHS who suffer from oropharyngeal and hypopharyngeal obstruction.
Yin
Shankai
S
Department of Otolaryngology, Affiliated Shanghai Sixth People's Hospital of Shanghai Jiao-tong University, Shanghai, 200233, China. yinshankai@china.com
Yi
Hongliang
H
Lu
Wenying
W
Wu
Hongmin
H
Guan
Jian
J
Cao
Zhenyu
Z
Chen
Ting
T
D000328:Adult; D000368:Aged; D002680:Chin / Q000601:surgery; D002972:Cleft Palate / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010159:Palate / Q000601:surgery*; D010614:Pharynx / Q000601:surgery; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D014059:Tongue / Q000601:surgery*; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery