title: The institutional review board and protecting human subjects: 10 frequently asked questions.
abstract: It is essential that anyone involved in research involving human subjects be familiar with the purpose and role of institutional review boards. Institutional review boards are designed, first and foremost, to protect human research subjects by overseeing the implementation of federal regulations regarding protection of human subjects. The federal government requires institutional review board approval for any human subject research that receives federal funding, and many scholarly journals require proof of institutional review board approval of the research before publication. In this article, the answers to 10 frequently asked questions about the role of institutional review boards highlight the important contributions made by institutional review boards to the conduct of ethically sound research. The aim is to generate a working knowledge of the institutional review board's function that can be used by every researcher contemplating working with human research subjects. This is the first in a series of 3 articles examining common issues in research ethics.
authors.affiliation: Department of Medical Ethics, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Sheldon
authors.initials: S
authors.lastname: Zink
authors.forename: Laura
authors.initials: L
authors.lastname: Kimberly
authors.forename: Stacey
authors.initials: S
authors.lastname: Wertlieb
mesh_terms: D032781:Codes of Ethics / Q000331:legislation & jurisprudence; D003219:Confidentiality / Q000941:ethics / Q000331:legislation & jurisprudence; D028744:Ethics Committees, Research / Q000941:ethics / Q000458:organization & administration; D032984:Ethics, Research; D035082:Federal Government; D006805:Human Experimentation / Q000941:ethics* / Q000331:legislation & jurisprudence; D006801:Humans; D009937:Organizational Objectives; D010344:Patient Advocacy / Q000941:ethics* / Q000331:legislation & jurisprudence; D010506:Periodicals as Topic / Q000941:ethics / Q000331:legislation & jurisprudence; D017410:Practice Guidelines as Topic; D028662:Principle-Based Ethics; D035842:Research Subjects / Q000331:legislation & jurisprudence; D012109:Research Support as Topic; D018570:Risk Assessment / Q000941:ethics / Q000331:legislation & jurisprudence; D015871:Scientific Misconduct / Q000941:ethics / Q000331:legislation & jurisprudence; D014481:United States