title: Ichthyosis follicularis, alopecia and photophobia (IFAP) syndrome treated with acitretin.
abstract: We describe a 3-year-old male patient with the ichthyosis follicularis, alopecia and photophobia (IFAP) syndrome, who developed cutaneous and ocular involvement in infancy. In addition, he had growth retardation and borderline intelligence; no other systemic involvement was found on detailed investigation. A moderate response to acitretin therapy (1 mg/kg) administered for 6 months was observed, with improvement in cutaneous features and corneal erosions and no change in alopecia or photophobia.
authors.affiliation: Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi 110029, India. shaifalikhandpur@eth.net
authors.forename: S
authors.initials: S
authors.lastname: Khandpur
authors.forename: R
authors.initials: R
authors.lastname: Bhat
authors.forename: M
authors.initials: M
authors.lastname: Ramam
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology; D017255:Acitretin / Q000627:therapeutic use*; D000505:Alopecia / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D007057:Ichthyosis / Q000188:drug therapy* / Q000473:pathology*; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D020795:Photophobia / Q000473:pathology*; D013577:Syndrome
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin