Cytoplasmic dynein nomenclature.
A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.
Pfister
K Kevin
KK
Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. kkp9w@virginia.edu
Fisher
Elizabeth M C
EM
Gibbons
Ian R
IR
Hays
Thomas S
TS
Holzbaur
Erika L F
EL
McIntosh
J Richard
JR
Porter
Mary E
ME
Schroer
Trina A
TA
Vaughan
Kevin T
KT
Witman
George B
GB
King
Stephen M
SM
Vallee
Richard B
RB
D000818:Animals; D003593:Cytoplasm / Q000201:enzymology*; D004398:Dyneins / Q000145:classification*; D006801:Humans; D009626:Terminology as Topic
D004398:Dyneins