Category-specific conceptual processing of color and form in left fronto-temporal cortex.
To investigate the cortical basis of color and form concepts, we examined event-related functional magnetic resonance imaging (fMRI) responses to matched words related to abstract color and form information. Silent word reading elicited activity in left temporal and frontal cortex, where category-specific activity differences were also observed. Whereas color words preferentially activated anterior parahippocampal gyrus, form words evoked category-specific activity in fusiform and middle temporal gyrus as well as premotor and dorsolateral prefrontal areas in inferior and middle frontal gyri. These results demonstrate that word meanings and concepts are not processed by a unique cortical area, but by different sets of areas, each of which may contribute differentially to conceptual semantic processing. We hypothesize that the anterior parahippocampal activation to color words indexes computation of the visual feature conjunctions and disjunctions necessary for classifying visual stimuli under a color concept. The predominant premotor and prefrontal activation to form words suggests action-related information processing and may reflect the involvement of neuronal elements responding in an either-or fashion to mirror neurons related to adumbrating shapes.
Pulvermüller
Friedemann
F
Medical Research Council, Cognition and Brain Sciences Unit, Cambridge CB2 2EF, UK. friedemann.pulvermuller@mrc-cbu.cam.ac.uk
Hauk
Olaf
O
D000328:Adult; D001931:Brain Mapping; D003118:Color Perception / Q000502:physiology*; D003210:Concept Formation / Q000502:physiology*; D005556:Form Perception / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D013702:Temporal Lobe / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*