Circadian dynamics of monocyte phagocytic activity in women during lactation complicated by iron deficiency.
Biorhythms of phagocytic activity of peripheral blood monocytes were studied during lactation in healthy women and in women with iron deficiency. Circadian organization of monocyte function was characteristic of healthy nursing women. Strain in the system was associated with elevation of the mean circadian values for reserve potential of the absorption and digestive capacity of phagocytes. Circadian rhythms of the phagocytic and digestive capacity of peripheral blood monocytes were leveled during lactation complicated by iron deficiency. Decreased coefficient of the parameters activation is an early manifestation of latent iron deficiency. Decrease in the basic function parameters and reserve potential are directly related to the decrease in serum ferritin concentration.
Barkova
E N
EN
Department of Pathophysiology, Tyumen State Medical Academy.
Nazarenko
E V
EV
D018798:Anemia, Iron-Deficiency / Q000503:physiopathology*; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007774:Lactation / Q000502:physiology*; D009000:Monocytes / Q000378:metabolism*; D010587:Phagocytosis / Q000502:physiology*
D005293:Ferritins