title: Burnout in clinical research coordinators in the United States.
abstract: OBJECTIVE
  To assess burnout among clinical research coordinators (CRCs) and to determine which personal and job-related factors are associated with burnout.
  
  
  METHODS
  Random, stratified, cross-sectional mail survey.
  
  
  METHODS
  CRCs from membership lists of clinical research organizations.
  
  
  METHODS
  252 CRCs in the United States. To be included in the study, participants must have been in their current position longer than six months and involved in clinical trial coordination or data management. Of 2,770 records, 900 CRCs were mailed questionnaires; 35% (316) responded, and 252 of those were eligible for analysis. Eligible respondents were Caucasian (86%), female (94%), and employed full-time (92%) in an oncology setting (71%).
  
  
  METHODS
  Respondents completed mailed self-administered questionnaires measuring burnout, job satisfaction, personality characteristics, perceived work overload, and selected personal- and employment-related data. Data analyses included descriptive, univariate, and multivariate statistics.
  
  
  METHODS
  Burnout.
  
  
  RESULTS
  About 70% of respondents were satisfied with their job, and 74% would still choose the clinical research profession. Approximately 44% reported high emotional exhaustion, a component of burnout. Factors independently associated with high emotional exhaustion burnout were low satisfaction with job (p 0.0001), high perceived daily workload (p 0.0001), and low endurance personality (p = 0.002).
  
  
  CONCLUSIONS
  Burnout is prevalent in CRCs. Job dissatisfaction, perceived daily work overload, low endurance, and nurturance personality traits were associated with high burnout.
  
  
  CONCLUSIONS
  Nurses are involved significantly in clinical trial coordination. High burnout rates have potentially negative implications for data quality and productivity in clinical trial data management-important values for nursing and the clinical research profession.
authors.affiliation: Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. gwede@moffitt.usf.edu
authors.forename: Clement K
authors.initials: CK
authors.lastname: Gwede
authors.forename: Darlene J
authors.initials: DJ
authors.lastname: Johnsson
authors.forename: Cleora
authors.initials: C
authors.lastname: Roberts
authors.forename: Alan B
authors.initials: AB
authors.lastname: Cantor
mesh_terms: D000288:Administrative Personnel / Q000706:statistics & numerical data*; D000328:Adult; D017677:Age Distribution; D000368:Aged; D035843:Biomedical Research / Q000458:organization & administration / Q000706:statistics & numerical data*; D002055:Burnout, Professional / Q000175:diagnosis / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D004644:Emotions; D005260:Female; D006306:Health Surveys; D006801:Humans; D007588:Job Satisfaction; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010551:Personality; D012108:Research Personnel / Q000706:statistics & numerical data*; D017678:Sex Distribution; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology