Hypoglycemic activity of a new carbohydrate isolated from the roots of Psacalium peltatum.
A new ulopyranose isolated from aqueous extract of roots and rhizomas of Psacalium peltatum has been determined to have hypoglycemic activity at doses of 100 mg/kg, comparable to that of tolbutamide and insulin in alloxan diabetic mice. The skeletal structure of the new compound was established by spectral analysis.
Contreras
Claudia
C
Departamento de Ciencias de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, México.
Román
Rubén
R
Pérez
Cuauhtemoc
C
Alarcón
Francisco
F
Zavala
Miguel
M
Pérez
Salud
S
D000107:Acetylation; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D001786:Blood Glucose / Q000737:chemistry; D002241:Carbohydrates / Q000302:isolation & purification* / Q000494:pharmacology*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D050112:Imino Pyranoses; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
D001786:Blood Glucose; D002241:Carbohydrates; D007004:Hypoglycemic Agents; D050112:Imino Pyranoses; D010936:Plant Extracts; C506636:petalosa