Effect of femoral nutrient artery ligature on radionuclide uptake in rabbits.
To elucidate the effect of damaging the nutrient artery to a long bone, we used radionuclide imaging to survey the change of femoral blood supply after ligating the nutrient artery in rabbits. The radionuclide uptake of the femoral shaft, upper and lower metaphysis, and epiphysis decreased significantly at 1 hr postoperation (0.66, 0.74, 0.81, respectively, p <0.05), were close to normal on day 4 (0.96, 0.98, 1.02, respectively, p >0.05), slightly exceeded the contralateral level at 9 and 12 days, and returned to normal on day 16. This study shows that ligation of the nutrient artery of a long bone leads to an immediate decrease in the bone blood flow. However, so long as anastomoses among other bone vessels are intact, the recovery rate is speedy, and long-term, serious disorders of the bone blood supply do not ensue.
Zeng
Xiaofeng
X
Department of Orthopaedics, Jinling Hospital, Nanjing University Medical School, Nanjing, PR China. zengxiaofeng@msn.com
Lu
Weiju
W
Zhao
Jianning
J
Guo
Ting
T
Li
Bin
B
D000818:Animals; D001158:Arteries / Q000502:physiology / Q000601:surgery; D005269:Femur / Q000098:blood supply / Q000000981:diagnostic imaging*; D006614:Hindlimb / Q000000981:diagnostic imaging; D008026:Ligation; D011817:Rabbits; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate