title: Cytoplasmic dynein nomenclature.
abstract: A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.
authors.affiliation: Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. kkp9w@virginia.edu
authors.forename: K Kevin
authors.initials: KK
authors.lastname: Pfister
authors.forename: Elizabeth M C
authors.initials: EM
authors.lastname: Fisher
authors.forename: Ian R
authors.initials: IR
authors.lastname: Gibbons
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Hays
authors.forename: Erika L F
authors.initials: EL
authors.lastname: Holzbaur
authors.forename: J Richard
authors.initials: JR
authors.lastname: McIntosh
authors.forename: Mary E
authors.initials: ME
authors.lastname: Porter
authors.forename: Trina A
authors.initials: TA
authors.lastname: Schroer
authors.forename: Kevin T
authors.initials: KT
authors.lastname: Vaughan
authors.forename: George B
authors.initials: GB
authors.lastname: Witman
authors.forename: Stephen M
authors.initials: SM
authors.lastname: King
authors.forename: Richard B
authors.initials: RB
authors.lastname: Vallee
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000201:enzymology*; D004398:Dyneins / Q000145:classification*; D006801:Humans; D009626:Terminology as Topic
chemical_list: D004398:Dyneins