title: [Impact of legislation on registration of acutely toxic pesticides in Brazil].
abstract: OBJECTIVE
  To evaluate the impact of the application of the "Pesticides Law" (Law no. 7,802/89) on the toxicological classification profile of registered pesticides in Brazil, from 1990 to 2000.
  
  
  METHODS
  Data on registered commercial products in the years 1990 and 2000 were analyzed according to toxicological class, date of registration of the active ingredient (before or after the Law) and usage class (insecticides, fungicides, herbicides and others). Relative Identified Distribution Analysis was utilized for verifying statistical differences between distributions according to toxicological classes.
  
  
  RESULTS
  Among the 863 registered commercial products in 2000, 46.6% were already registered before the Pesticide Law. Among the 461 commercial products registered after the Law, 59.2% were derivatives of active ingredients registered before the Law, and 41.4% were classified as highly hazardous (classes I and II of the Brazilian toxicological classification). No significant differences in toxicological classification profile were identified between the group of pesticides derived from active ingredients registered before the Law and the group derived from active ingredients registered after the Law (p<0.0859).
  
  
  CONCLUSIONS
  Ten years after the Pesticide Law came into effect, no significant improvement had been observed in the toxicological classification profile of registered pesticides. This was due especially to the continuing presence of products registered before the Law and the registration of new commercial products derived from "old" active ingredients. There was still a high proportion of registrations in the most hazardous classes. It is recommended that compulsory periodic reevaluation of all registered pesticides should be reestablished.
authors.affiliation: Fundação Jorge Duprat Figueiredo de Segurança e Medicina no Trabalho (Fundacentro), São Paulo, SP, Brazil. edgarcia@fundacentro.gov.br
authors.forename: Eduardo Garcia
authors.initials: EG
authors.lastname: Garcia
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Bussacos
authors.forename: Frida Marina
authors.initials: FM
authors.lastname: Fischer
mesh_terms: D001938:Brazil; D006801:Humans; D007880:Legislation, Drug; D010575:Pesticides / Q000145:classification / Q000633:toxicity*; D012042:Registries / Q000706:statistics & numerical data*
chemical_list: D010575:Pesticides