title: Severe rheumatoid valvular heart disease.
abstract: Rheumatoid arthritis (RA) is a systemic inflammatory disease in which extra-articular involvement is not uncommon. Cardiac compromise may be frequent, although most often, it is clinically silent. Herein, two cases of RA-related endocarditis, one of which required valve replacement, are described. Etanercept was useful in controlling the articular and extra-articular RA compromise in both cases.
authors.affiliation: Unidad de Biología Celular e Inmunogenética, Corporación para Investigaciones Biológicas, Universidad del Rosario, Cra. 72-A No 78-B-141, Medellín, Colombia. janaya@cib.org.co
authors.forename: Juan-Manuel
authors.initials: JM
authors.lastname: Anaya
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D002216:Captopril; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004696:Endocarditis / Q000150:complications* / Q000473:pathology / Q000628:therapy; D000068800:Etanercept; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000473:pathology / Q000628:therapy; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use; D012074:Remission Induction
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D002216:Captopril; D000068800:Etanercept