title: Granulocytic adhesive interactions and their role in sickle cell vaso-occlusion.
abstract: Recent research has high-lighted the importance of leukocytes in sickle cell disease (SCD). Here we summarize evidence to show that the granulocytes may play a role in SCD due to their increased numbers and adhesive properties, facilitating their participation in the vaso-occlusive process.
authors.affiliation: Hematology and Hemotherapy Center, State University of Campinas-UNICAMP, Brazil. andreiaa.c@uol.com.br
authors.forename: Andreia Averci
authors.initials: AA
authors.lastname: Canalli
authors.forename: Fernando Ferreira
authors.initials: FF
authors.lastname: Costa
authors.forename: Sara T O
authors.initials: ST
authors.lastname: Saad
authors.forename: Nicola
authors.initials: N
authors.lastname: Conran
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications / Q000378:metabolism*; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D006098:Granulocytes / Q000378:metabolism*; D006801:Humans; D014652:Vascular Diseases / Q000209:etiology / Q000378:metabolism*
chemical_list: D015815:Cell Adhesion Molecules