title: Acute lymphoblastic leukaemia in pregnancy.
abstract: Two cases of pregnant patients with acute lymphoblastic leukaemia (ALL) are presented. ALL is rare in pregnancy. The basic principle of ALL treatment is combination chemotherapy with sequential administration of induction, consolidation and maintenance therapy, and this also holds for ALL in pregnancy. The prognosis of ALL in pregnancy is poor and termination of the pregnancy needs to be considered.
authors.affiliation: Department of Obstetrics and Gynaecology, Maastricht University Hospital, Maastricht, the Netherlands. jfmm@xs4all.nl
authors.forename: J F M
authors.initials: JF
authors.lastname: Molkenboer
authors.forename: A H
authors.initials: AH
authors.lastname: Vos
authors.forename: H C
authors.initials: HC
authors.lastname: Schouten
authors.forename: M C
authors.initials: MC
authors.lastname: Vos
mesh_terms: D000028:Abortion, Induced; D000022:Abortion, Spontaneous; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000188:drug therapy; D011379:Prognosis