[Investigate the early impairment of renal function caused by chronic tonsillitis].
OBJECTIVE
To investigate whether the chronic tonsillitis have early impairment of renal function or not.


METHODS
Enzyme linked immunosorbent assay (ELISA) was used to detect the urinary microalbumin of 77 samples of chronic tonsillitis (group A: course of diseases is 1 to 3 years; group B: course of diseases is 3 to 5 years; group C: course of diseases is over 5 years) and 20 samples of normal (group D) respectively and the results were compared, including the detection and comparison of the urinary microalbumin of 19 samples of chronic tonsillitis preoperative and postoperative.


RESULTS
(1) group A: the urinary microalbumin is (9.8 +/- 1.6)mg/L; group B: the urinary microalbumin is (12.3 2.2) mg/L; group C: the urinary microalbumin is (17.6 +/- 3.2)mg/L; group D: the urinary microalbumin is (9.6 +/- 2.0) mg/L. The urinary microalbumin of chronic tonsillitis group C was higher than group D, there was a significant difference between these two groups ( P < 0.05). (2) The urinary microalbumin of chronic tonsillitis was (26.3 +/- 2.2)mg/L preoperatively and was (18.7 +/- 1.7)mg/L postoperatively. The urinary microalbumin of chronic tonsillitis significantly decreased after they had been surgical treated (P < 0.05).


CONCLUSIONS
The urinary microalbumin of chronic tonsillitis was uptrend according to its course of diseases. The detection of the urinary microalbumin could be one of the diagnostic message for the early impairment of renal function which has been caused by chronic tonsillitis. The detection of the urinary microalbumin is important to evaluate the surgical treatment of chronic tonsillitis.
Luo
Rong
R
Department of Otolaryngology, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, China.
Kong
Weijia
W
D000328:Adult; D016022:Case-Control Studies; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D009393:Nephritis / Q000209:etiology*; D014069:Tonsillitis / Q000150:complications*; D016482:Urinalysis