title: Risk factors for bacterial vaginosis in women at high risk for sexually transmitted diseases.
abstract: OBJECTIVE AND GOAL: Bacterial vaginosis (BV) is extremely common and is associated with adverse obstetrical and gynecological outcomes. The etiology of the microbiologic changes is unknown. The objective of this study was to determine risk factors associated with incident BV.
  
  
  METHODS
  96 women without BV were followed prospectively for 1 year for the development of BV. Thirty-seven of their male partners were also studied.
  
  
  RESULTS
  The incidence rate of BV was 2.33/person-year (95% CI, 1.63-2.50). Median time to development of BV was 81 days. Incident BV was significantly associated with exposure to a new sexual partner (RR, 1.13; 95% CI, 1.02-1.25; P = 0.02) and frequency of vaginal sex since last visit (RR, 1.07; 95% CI, 1.01-1.15; P = 0.03). Use of condoms with occasional partners was protective (RR, 0.80; 95% CI, 0.67-0.98; P = 0.003). In multivariate analysis, sex with a new partner since the prior visit was the only behavior found to be significantly associated with incident BV (RR, 1.74; 95% CI, 1.05-2.87; P = 0.03).
  
  
  CONCLUSIONS
  These data support the sexual transmission of BV.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA. schwebke@uab.edu
authors.forename: Jane R
authors.initials: JR
authors.lastname: Schwebke
authors.forename: Renee
authors.initials: R
authors.lastname: Desmond
mesh_terms: D000293:Adolescent; D000328:Adult; D017280:Condoms / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D012307:Risk Factors; D012725:Sexual Behavior; D012747:Sexual Partners; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000635:transmission*; D016585:Vaginosis, Bacterial / Q000453:epidemiology* / Q000635:transmission*