[Adhesion and migration functions of peripheral blood leukocytes in children with chronic gastroduodenitis].
The goal of the research was to study the peculiarities of adhesion and migration characteristics of leukocytes in children with chronic gastroduodenitis as compared to patients with functional dyspepsia and healthy children. An increase in the values of spontaneous adhesion and migration was noted in lymphocytes, monocytes and neutrophils during the exacerbation period of gastroduodenitis, which correlates with clinical manifestations, data of the morphological study and intragastric pH-metry. At the same time, a reduction in the functional reserve of leukocytes and their sensibility to adhesion stimulators. The dynamics of the examined characteristics was determined after the treatment. The results obtained are the evidence of the possibility to use the parameters of adhesion and migration capabilities of leukocytes for diagnosing chronic gastroduodenitis.
Krasnova
E E
EE
Chemodanova
V V
VV
Klykova
E N
EN
D002448:Cell Adhesion; D002465:Cell Movement; D002648:Child; D002908:Chronic Disease; D004382:Duodenitis / Q000175:diagnosis* / Q000276:immunology; D005756:Gastritis / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007962:Leukocytes / Q000276:immunology*