[How should potential selection for bacterial antibiotic resistance be defined?].
Evolution of bacterial resistance to antibiotics could be better controlled if we knew how to define the potential of evolution of bacterial resistance towards a given antibiotic, prospectively. No unique method allows to do it. Pieces of answers can be obtained by using diverse methods using bacteriological, ecological pharmaco-epidemiological techniques and experimental models. Association of the results obtained with these various techniques is mandatory to understand the evolution potential of resistance towards a given antibiotic when it is used in the clinical setting.
Andremont
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Laboratoire de bactériologie, Hôpital Bichat Claude-Bernard, AP-HP, 75018 Paris, France. antoine.andremont@bch.aphp.fr
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005075:Biological Evolution; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009626:Terminology as Topic
D000900:Anti-Bacterial Agents