Detection of volatile metabolites produced by bacterial growth in blood culture media by selected ion flow tube mass spectrometry (SIFT-MS).
To achieve faster bacteremia diagnosis, selected ion flow tube mass spectrometry (SIFT-MS) measured metabolic gases in the headspaces of BacT/ALERT blood culture bottles. Pseudomonas aeruginosa, Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and Neisseria meningitidis growth and trace gas patterns were detected from 10 colony forming units after 6 h.
Allardyce
Randall A
RA
Department of Surgery, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand. randall.allardyce@chmeds.ac.nz
Langford
Vaughan S
VS
Hill
Alex L
AL
Murdoch
David R
DR
D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology; D001419:Bacteria / Q000254:growth & development* / Q000378:metabolism*; D001431:Bacteriological Techniques / Q000295:instrumentation / Q000379:methods; D001769:Blood / Q000382:microbiology; D003470:Culture Media; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D009930:Organic Chemicals / Q000032:analysis*; D014835:Volatilization
D003470:Culture Media; D009930:Organic Chemicals