[Research progress in the reversion of traditional Chinese medicine on multidrug resistance of tumor].
Researches on MDR (multidrug resistance) of tumor presently focus on seeking chemosensitizers with more targets, high efficiency and low toxicity from traditional Chinese medicine. This paper reviews the research progress in the reversion of MDR of leukemia, hepatocarcinoma, breast carcinoma and oral epithelioid neoplasia by TDM compound, its extracts, its groups of active ingredients or its active ingredients.
Song
Xiang-rong
XR
West China College of Pharmacy, Sichuan University, Chengdu 610041, China.
Hou
Shi-xiang
SX
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000096:biosynthesis / Q000235:genetics; D000818:Animals; D001943:Breast Neoplasms / Q000378:metabolism; D006528:Carcinoma, Hepatocellular / Q000378:metabolism; D004250:DNA Topoisomerases, Type II / Q000378:metabolism; D004338:Drug Combinations; D018432:Drug Resistance, Multiple / Q000187:drug effects*; D019008:Drug Resistance, Neoplasm / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D019450:Genes, MDR; D006801:Humans; D007938:Leukemia / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism*; D008516:Medicine, Chinese Traditional; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D004250:DNA Topoisomerases, Type II; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D012333:RNA, Messenger