title: Surgical treatment and outcome of conventional pelvic chondrosarcoma.
abstract: We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival. More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develop metastases or cause death, while grade 3 tumours had the worst outcome and prognosis. Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.
authors.affiliation: Orthopaedic Division, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy. davide.donati@ior.it
authors.forename: D
authors.initials: D
authors.lastname: Donati
authors.forename: A
authors.initials: A
authors.lastname: El Ghoneimy
authors.forename: F
authors.initials: F
authors.lastname: Bertoni
authors.forename: C
authors.initials: C
authors.lastname: Di Bella
authors.forename: M
authors.initials: M
authors.lastname: Mercuri
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery*; D002813:Chondrosarcoma / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D023821:Limb Salvage; D009364:Neoplasm Recurrence, Local; D010384:Pelvic Bones; D011379:Prognosis; D016019:Survival Analysis; D016896:Treatment Outcome