Preparation of (Cyanomethylene)tributylphosphorane: a new mitsunobu-type reagent.
(Cyanomethylene)tributylphosphorane (CMBP), which promoted the alkylation of various nucleophiles (HA) with alcohols (ROH) to give RA (Mitsunobu-type reaction), was prepared in two steps starting from chloroacetonitrile.
Sakamoto
Izumi
I
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.
Nishii
Takeshi
T
Ozaki
Fumie
F
Kaku
Hiroto
H
Tanaka
Masami
M
Tsunoda
Tetsuto
T
D000097:Acetonitriles; D000438:Alcohols; D000478:Alkylation; D007202:Indicators and Reagents / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D014050:Toluene
D000097:Acetonitriles; D000438:Alcohols; D007202:Indicators and Reagents; D014050:Toluene; C069277:chloroacetonitrile