title: RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma.
authors.affiliation: Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Mukesh K
authors.initials: MK
authors.lastname: Sharma
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Zehnbauer
authors.forename: Mark A
authors.initials: MA
authors.lastname: Watson
authors.forename: David H
authors.initials: DH
authors.lastname: Gutmann
mesh_terms: D001254:Astrocytoma / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D001932:Brain Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D002648:Child; D003062:Codon / Q000235:genetics; D004252:DNA Mutational Analysis; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics; D008297:Male; D009154:Mutation / Q000235:genetics*; D025542:Neurofibromin 1 / Q000235:genetics; D017354:Point Mutation / Q000235:genetics; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases / Q000235:genetics; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics*; D015398:Signal Transduction / Q000235:genetics
chemical_list: D003062:Codon; D047908:Intracellular Signaling Peptides and Proteins; D025542:Neurofibromin 1; D051057:Proto-Oncogene Proteins c-akt; C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases; D016283:Proto-Oncogene Proteins p21(ras)