title: Alpha-nitro ketone synthesis using N-acylbenzotriazoles.
abstract: [Reaction: see text]. Readily available N-acylbenzotriazoles 2a-l (derived from a variety of aliphatic, (hetero)aromatic, and N-protected alpha-amino carboxylic acids) smoothly convert primary 3a-c and alpha-functionalized primary nitroalkanes 3d into the corresponding alpha-nitro ketones 5a-p in yields of 39-86% (average 63%).
authors.affiliation: Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA.
authors.forename: Alan R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: Ashraf A A
authors.initials: AA
authors.lastname: Abdel-Fattah
authors.forename: Anna V
authors.initials: AV
authors.lastname: Gromova
authors.forename: Rachel
authors.initials: R
authors.lastname: Witek
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Steel