Clinical predictors of a positive troponin T test in patients presenting with probable acute coronary syndromes.
Acute coronary syndrome (ACS) patients with positive troponin T (TnT) test are at higher risk for death and myocardial reinfarction. They would significantly benefit from early aggressive pharmacologic and invasive therapy. However, TnT test is not widely available. This retrospective study of 173 patients with ACS showed: that prolonged or repetitive episodes of angina at rest in the previous 24 hours (p = 0.01) and evidence of myocardial ischaemia on ECG (p < 0.001) were associated with positive TnT tests (> or = 0.1 ng/mL). The two variables in combination showed 100% positive predictive value, facilitating early identification and streamlining of therapy.
Omar
A R
AR
Cardiac Department, National University Hospital, The Heart Institute, National University Hospital, The Heart Institute, 5 Lower Kent Ridge, Road Level 3, Main Building, Singapore 119074.
Ping
Chai
C
Tan
H C
HC
Lim
Y T
YT
D000208:Acute Disease; D000789:Angina, Unstable / Q000097:blood*; D006801:Humans; D017202:Myocardial Ischemia / Q000097:blood*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013577:Syndrome; D020107:Troponin T / Q000097:blood*
D020107:Troponin T