title: Recurrent dysphonia and acitretin.
abstract: We report the case of a woman complaining of dysphonia while she was treated by acitretin. Her symptoms totally regressed after drug withdrawal and reappeared when acitretin was reintroduced. To our knowledge, this is the first case of acitretin-induced dysphonia. This effect may be related to the pharmacological effect of this drug on mucous membranes.
authors.affiliation: Department of Clinical Pharmacology, University Hospital, Nancy, France. crpv@chu-nancy.fr
authors.forename: N
authors.initials: N
authors.lastname: Petitpain
authors.forename: J
authors.initials: J
authors.lastname: Pouaha
authors.forename: F
authors.initials: F
authors.lastname: Cosserat
authors.forename: N
authors.initials: N
authors.lastname: Gambier
authors.forename: F
authors.initials: F
authors.lastname: Truchetet
authors.forename: J-F
authors.initials: JF
authors.lastname: Cuny
mesh_terms: D017255:Acitretin / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000188:drug therapy*; D007641:Keratolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D012008:Recurrence; D014832:Voice Disorders / Q000139:chemically induced* / Q000503:physiopathology*
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin