[Ocular features of polyneuropathy-organomegaly-endocrinopathy-monoclonal gammopathy-skin changes syndrome].
OBJECTIVE
To analyze the ocular features of POEMS syndrome, and explore the pathogenesis.


METHODS
Fifteen cases with POEMS syndrome from 1984-2004 were reviewed and summarized. The ocular features and the intracranial pressures were analyzed.


RESULTS
Three of 15 patients showed blurred vision. Seven of 15 patients had mild papilloedema, five had fully papilloedema, and the optic discs in other three cases were normal. Intracranial pressures were measured in 11 of 15 patients. Seven of 8 patients with papilloedema had elevated intracranial pressures.


CONCLUSIONS
Papilloedema is found in about 80.0% patients with POEMS syndrome. Most of the patients with papilloedema have elevated intracranial pressures.
Dai
Rong-ping
RP
Eye Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Department of Ophthalmology, Peking Union Medical College Hospital, Beijing 100730, China.
Dong
Fang-tian
FT
Chu
Jie
J
D000328:Adult; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D016878:POEMS Syndrome / Q000175:diagnosis*; D010211:Papilledema / Q000175:diagnosis*; D012189:Retrospective Studies