Highly regio- and enantioselective palladium-catalyzed allylic alkylation and amination of dienyl esters with 1,1'-P,N-ferrocene ligands.
[reaction, structure: see text] Pd-catalyzed asymmetric allylic alkylation of dienyl acetates 1 and amination of allyl acetates 2 provides the corresponding chiral products in high regio- and enantioselectivities using 1,1'-P,N-ferrocenes L1a and L2d as ligands, respectively.
Zheng
Wen-Hua
WH
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Sun
Na
N
Hou
Xue-Long
XL