title: The assessment of quality of life in patients who have undergone surgery for oral cancer: a preliminary report.
abstract: OBJECTIVE
  The outcome of management strategies for the treatment of oral cancer has always been in terms of disease-specific survival. Modern assessment of outcome now also includes assessment of quality of life (QOL). Little has been done previously in Australia to assess the QOL of patients treated primarily by surgery for oral cancer.
  
  
  METHODS
  Twenty-two patients who had undergone primary surgical management for oral cancer underwent assessment of QOL using the European Organization for Research and Treatment of Cancer QOL questionnaire version 3 (EORTC QLQ-C30) and the University of Washington Head and Neck QOL questionnaire version 4 (UWQOL). Similar emotional domains were compared and factors affecting QOL were determined.
  
  
  RESULTS
  Fifty-five percent of patients were male and 45% were female. The mean age was 61.8 years (range, 38 to 86 years) with a mean review time of 24.6 months (SD, 20.3 months) postoperatively. Good QOL scores were experienced by most patients. A new addition to the UWQOL version 4 was the mood and anxiety domains, and these correlated well with the emotional domains of the EORTC QLQ-C30 using Spearman rank correlations. Factors significantly affecting survival included age, overall stage, neck dissection, free flap, and postoperative radiotherapy using Mann-Whitney tests (P < .05). No significant difference in QOL was found in patients reviewed at either less than or greater than 1 year.
  
  
  CONCLUSIONS
  This study confirms previous reports in the literature. It has provided us with the foundation for further investigation of QOL in patients who have been and who will be treated for oral cancer. It also gives us a new measure of outcome to compare against survival rates.
authors.affiliation: Oral and Maxillofacial Surgery, Austin Health, Heidelberg, Victoria, Australia.
authors.forename: Arun
authors.initials: A
authors.lastname: Chandu
authors.forename: Kenneth C V
authors.initials: KC
authors.lastname: Sun
authors.forename: Rajeev N
authors.initials: RN
authors.lastname: DeSilva
authors.forename: Andrew C H
authors.initials: AC
authors.lastname: Smith
mesh_terms: D000328:Adult; D000368:Aged; D001315:Australia; D003430:Cross-Sectional Studies; D004644:Emotions; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000523:psychology* / Q000601:surgery*; D017063:Outcome Assessment, Health Care / Q000379:methods*; D010865:Pilot Projects; D011788:Quality of Life / Q000523:psychology*; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires