title: Renal amyloidosis: an uncommon complication of juvenile idiopathic arthritis.
abstract: A 9-year-old girl presented with systemic-onset juvenile idiopathic arthritis, diagnosed at 3.5 of age and which was difficult to control despite several therapeutic trials. Five years after diagnosis of juvenile idiopathic arthritis, nephrotic proteinuria was noticed. Renal biopsy confirmed the diagnosis of amyloidosis, and chlorambucil was initiated, with general improvement of the disease and reduction of proteinuria.
authors.affiliation: Unidade de Nefrologia do Hospital Pediátrico de Coimbra, Avenida Bissaya Barreto, 3000, Coimbra, Portugal. carolduarte@netcabo.pt
authors.forename: Carolina
authors.initials: C
authors.lastname: Duarte
authors.forename: Clara
authors.initials: C
authors.lastname: Gomes
authors.forename: A Jorge
authors.initials: AJ
authors.lastname: Correia
authors.forename: Manuel
authors.initials: M
authors.lastname: Salgado
mesh_terms: D017668:Age of Onset; D000686:Amyloidosis / Q000150:complications* / Q000188:drug therapy; D001171:Arthritis, Juvenile / Q000150:complications*; D002648:Child; D002699:Chlorambucil / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology; D011507:Proteinuria / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D002699:Chlorambucil