[Effects of reduced dialysate calcium on mineral metabolism in hemodialysis patients].
OBJECTIVE
To study the effects of decreased dialysis calcium on mineral metabolism.


METHODS
Dialysis calcium concentration was switched from 3.0 mEq/L to 2.5 mEq/L. Changes of serum Ca, P, and PTH were monitored for 6 months in 58 hemodialysis patients.


RESULTS
Serum calcium decreased 2 weeks after the switch of dialysate, although it returned to the basal level after 6 months because of increased dosage of vitamin D. Phosphorus transiently increased after the switch. I-PTH increased in patients whose i-PTH before the switch was less than 100 pg/mL. PTH decreased in patients whose i-PTH exceeded 300 pg/mL.


CONCLUSIONS
Decreased dialysis calcium produced lower serum calcium and better PTH control.
Fujimori
Akira
A
Department of Artificial Kidney, Konan Hospital.
Yorifuji
Masahiko
M
Sakai
Makoto
M
Fukagawa
Masafumi
M
D002118:Calcium / Q000032:analysis* / Q000097:blood*; D015312:Hemodialysis Solutions / Q000737:chemistry*; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood*; D006435:Renal Dialysis; D013997:Time Factors; D014807:Vitamin D / Q000008:administration & dosage
D015312:Hemodialysis Solutions; D010281:Parathyroid Hormone; D014807:Vitamin D; D010758:Phosphorus; D002118:Calcium