title: Sclerotherapy of benign oral vascular lesion with ethanolamine oleate: an open clinical trial with 30 lesions.
abstract: OBJECTIVE
  The objective of this study was to report and discuss the results from treatment of benign oral vascular lesions with ethanolamine oleate.
  
  
  METHODS
  Twenty-seven patients with 30 examples of oral vascular malformation, hemangioma, or varix were treated with intralesional injections of 1.25% or 2.5% ethanolamine oleate at an interval of 15 days between each application. The lesions were divided into 2 categories: (1) lesions of 20 mm or less and (2) those greater than 20 mm. Subsequently, the Mann-Whitney test was used a means of statistical analysis.
  
  
  RESULTS
  Although the number of injections varied from patient to patient, all lesions responded to the treatment, showing total clinical regression. Lesions of 20 mm or less needed a lesser number of applications than those greater than 20 mm (P < .05).
  
  
  CONCLUSIONS
  Ethanolamine oleate is a 100% effective sclerosant agent for treatment of benign oral vascular lesions. In this study, no difference was found between the 2 concentrations applied.
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Federal University of the Minas Gerais, Minas Gerais, Brazil.
authors.forename: Aline Cristina Batista Rodrigues
authors.initials: AC
authors.lastname: Johann
authors.forename: Maria Cássia Ferreira
authors.initials: MC
authors.lastname: Aguiar
authors.forename: Maria Auxiliadora Vieira
authors.initials: MA
authors.lastname: do Carmo
authors.forename: Ricardo Santiago
authors.initials: RS
authors.lastname: Gomez
authors.forename: Wagner Henriques
authors.initials: WH
authors.lastname: Castro
authors.forename: Ricardo Alves
authors.initials: RA
authors.lastname: Mesquita
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000628:therapy; D002648:Child; D005260:Female; D006391:Hemangioma / Q000628:therapy; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000628:therapy*; D009062:Mouth Neoplasms / Q000628:therapy*; D009383:Neoplasms, Vascular Tissue / Q000628:therapy*; D009829:Oleic Acids / Q000008:administration & dosage*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D015911:Sclerotherapy; D018709:Statistics, Nonparametric; D014648:Varicose Veins / Q000628:therapy; D014652:Vascular Diseases / Q000628:therapy*
chemical_list: D009829:Oleic Acids; D012597:Sclerosing Solutions; C033343:ethanolamine oleate