[Two patients with hyperparathyroidism which was progressive for more than ten years after successful kidney transplantation].
It is well known that in some patients advanced renal hyperparathyroidism (HPT) persists after successful kidney transplantation (RTx) and in those patients parathyroidectomy is required usually within one year after RTx. We experienced two patients with advanced renal HPT which released after successful RTx and parathyroidectomy was performed in more than 10 years after RTx, even their kidney function was well-preserved. Hypercalcemia was gradually progressive for ten years after RTx and enlarged parathyroid glands were detected by image diagnosis. We performed parathyroidectomy and HPT was dramatically improved. It is possible that primary HPT occurred de novo after RTx or renal HPT was progressive. We evaluated those possibility based on histopathological findings dramatically improved of removed parathyroid glands.
Uno
Nobuaki
N
Department of Surgery, Renal center Nagoya Daini Red Cross Hospital.
Tominaga
Yoshihiro
Y
Sato
Tetsuhiko
T
Goto
Noriaki
N
Matsuoka
Susumu
S
Kataoka
Akio
A
Haba
Toshihito
T
Uchida
Kazuharu
K
D018450:Disease Progression; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006962:Hyperparathyroidism, Secondary / Q000209:etiology* / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D016105:Parathyroidectomy; D013997:Time Factors