[The effect of Chitosan on intraocular structure when filling in the vitreous cavity].
OBJECTIVE
To study the effect of Chitosan on intraocular structure and pressure when filling in the vitreous body.


METHODS
Chitosan were injected into vitreous cavity in twelve healthy vitrectomized pigmented rabbits in the right eyes (experiment group) and Hyalumnan in the left eyes (control group). Slitlamp biomicroscopy and indirect ophthalmoscopy were performed and intraocular pressure were measured pre- and postoperatively in all eyes. Histopathological examination was done after the rabbits were sacrificed at the end of the study.


RESULTS
All the results indicated that there were no significant differences between experiment group and control group.


CONCLUSIONS
There is no obvious effect on intraocular structure and intraocular pressure when the vitreous cavity is filled with Chitosan.
Yang
Hong
H
Department of Ophthalmology, Tongji Hospital, Tongji Medical College of Science and Technology University, Wuhan 430030, China. hyang@tjh.tjmu.edu.cn
Wang
Rong
R
Zhang
Xiao-nong
XN
D000818:Animals; D048271:Chitosan / Q000494:pharmacology*; D002924:Ciliary Body / Q000187:drug effects; D003315:Cornea / Q000187:drug effects; D005260:Female; D056965:Injections, Intraocular; D007429:Intraocular Pressure / Q000187:drug effects*; D007908:Lens, Crystalline / Q000187:drug effects; D008297:Male; D011817:Rabbits; D012160:Retina / Q000187:drug effects*; D014822:Vitreous Body
D048271:Chitosan