Gold nanoparticle decoration of DNA on silicon.
Electrostatic assembly of cationic nanoparticles onto the negatively charged backbone of double-stranded DNA has been shown to produce one-dimensional chains with potential use as nanoelectronic components. In this paper, micron long DNA templates stretched on aminosilane- and hexamethyldisilazane-modified silicon surfaces are used to assemble 3.5 nm gold nanoparticles passivated with cationic thiocholine. Atomic force microscopy is used to analyze the density and defects along the approximately 5 nm high structures, with comparison between positively charged and neutral surfaces. Low background adsorption of nanoparticles is facilitated by both these surface chemistries, while the neutral surface yields a more densely packed assembly.
Braun
Gary
G
Department of Chemistry and Biochemistry, Biomolecular Science and Engineering Program, University of California, Santa Barbara, 93106-9510, USA.
Inagaki
Katsuhiko
K
Estabrook
R August
RA
Wood
D K
DK
Levy
Eran
E
Cleland
A N
AN
Strouse
Geoffrey F
GF
Reich
Norbert O
NO
D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles; D018625:Microscopy, Atomic Force; D012825:Silicon / Q000737:chemistry*
D006046:Gold; D004247:DNA; D012825:Silicon