Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ.
Wu
Chung-Yi
CY
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Brik
Ashraf
A
Wang
Sheng-Kai
SK
Chen
Yu-Hsien
YH
Wong
Chi-Huey
CH
D000478:Alkylation; D000588:Amines; D002264:Carboxylic Acids; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004791:Enzyme Inhibitors / Q000032:analysis*; D046228:Microarray Analysis; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012997:Solvents; D013449:Sulfonamides; D014230:Triazoles
D000588:Amines; D002264:Carboxylic Acids; D004791:Enzyme Inhibitors; D000644:Quaternary Ammonium Compounds; D012997:Solvents; D013449:Sulfonamides; D014230:Triazoles; C009405:tetrabutylammonium