A one-step synthesis of 2-Alkyl-5-hydroxychromones and 3-Alkoyl-2-alkyl-5-hydroxychromones.
2-Alkyl-5-hydroxychromones (2-alkyl-5-hydroxy-4-oxo-4H-1-benzopyran) and 3-alkoyl-2-alkyl-5-hydroxychromones (3-alkoyl-2-alkyl-5-hydroxy-4-oxo-4H-1-benzopyran) were prepared in one-step and one pot reaction by condensation of 2',6'-dihydroxyacetophenone with an alkoyl chloride in the presence of K2CO3.
Okombi
Sabrina
S
Département de Pharmacochimie Moléculaire UMR-CNRS 5063, Université Joseph Fourier de Grenoble, Faculté de Pharmacie, Meylan, France.
Schmidt
Julien
J
Mariotte
Anne-Marie
AM
Perrier
Eric
E
Boumendjel
Ahcène
A
D002867:Chromones / Q000138:chemical synthesis*; D003500:Cyclization; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
D002867:Chromones; D007202:Indicators and Reagents