[The non-neuronal cholinergic system in immunocompetent cells].
Most of the cholinergic components, which are expressed in neurons, exist in the immunocompetent cells, especially the lymphocytes, and thus constitute an independent cholinergic system. Comparing with neuronal cholinergic system, the non-neuronal cholinergic system has its unique characteristics, and may be involved in regulation of immune function and inflammatory responses in human and other mammals. An insight into the non-neuronal cholinergic system in immunocompetent cells may facilitate further understanding of pathophysiology and novel therapeutics of immune abnormalities, infectious diseases and neurodegenerative diseases.
Li
Juan
J
Department of Pharmacology, Shanghai Second Medical University, Shanghai 200025.
Chen
Hong-Zhuan
HZ
D000109:Acetylcholine / Q000096:biosynthesis / Q000502:physiology*; D000818:Animals; D006801:Humans; D007107:Immune System / Q000166:cytology / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism
D000109:Acetylcholine