High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora.
The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.
Domingo
M-C
MC
Centre de Recherche en Infectiologie de l'Université Laval, CHUQ (Pavillon CHUL), 2705 boul. Laurier, Sainte-Foy, Québec, G1V 4G2, Canada.
Huletsky
A
A
Giroux
R
R
Boissinot
K
K
Picard
F J
FJ
Lebel
P
P
Ferraro
M J
MJ
Bergeron
M G
MG
D001426:Bacterial Proteins / Q000235:genetics*; D004352:Drug Resistance, Microbial / Q000235:genetics*; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D006801:Humans; D010453:Peptide Synthases / Q000235:genetics*; D016133:Polymerase Chain Reaction; D020713:Vancomycin Resistance / Q000235:genetics*
D001426:Bacterial Proteins; C079913:VanB protein, Enterococcus; C417270:VanG protein, Enterococcus faecalis; D010453:Peptide Synthases; C122181:VanD protein, Enterococcus faecium