[Morphopathological study in age related macular degeneration].
The aim of this paper is to study the morphopathological changes manifested in age-related macular degeneration.


METHODS
The researched histopathological material consisted in two eye balls enucleated because of irreversible eye diseases from aged persons suffering from age-related macular degeneration. The method applied for processing the material was inclusion in paraffin, followed by usual coloration with hematoxylin-eosin.


CONCLUSIONS
The established changes (hard drusen, soft drusen, calcified drusen, changes of Bruch's membrane, subretinal neovascularization, serous retinal pigment epithelial detachment, disciform degeneration) prove the importance of Bruch's membrane in the pathogenesis of age-related macular degeneration.
Simionescu
Cristiana
C
Disciplina Morfopatologie, UMF Craiova.
Birău
Carmen
C
D000368:Aged; D000369:Aged, 80 and over; D016570:Bruch Membrane / Q000473:pathology; D006801:Humans; D008268:Macular Degeneration / Q000473:pathology*; D008853:Microscopy; D015593:Retinal Drusen / Q000473:pathology; D015861:Retinal Neovascularization / Q000473:pathology