title: Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ.
authors.affiliation: Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Chung-Yi
authors.initials: CY
authors.lastname: Wu
authors.forename: Ashraf
authors.initials: A
authors.lastname: Brik
authors.forename: Sheng-Kai
authors.initials: SK
authors.lastname: Wang
authors.forename: Yu-Hsien
authors.initials: YH
authors.lastname: Chen
authors.forename: Chi-Huey
authors.initials: CH
authors.lastname: Wong
mesh_terms: D000478:Alkylation; D000588:Amines; D002264:Carboxylic Acids; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004791:Enzyme Inhibitors / Q000032:analysis*; D046228:Microarray Analysis; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012997:Solvents; D013449:Sulfonamides; D014230:Triazoles
chemical_list: D000588:Amines; D002264:Carboxylic Acids; D004791:Enzyme Inhibitors; D000644:Quaternary Ammonium Compounds; D012997:Solvents; D013449:Sulfonamides; D014230:Triazoles; C009405:tetrabutylammonium