title: Ethnic differences in donation-related characteristics among potential hematopoietic stem cell donors.
abstract: BACKGROUND
  Although the National Marrow Donor Program has been highly successful at recruiting ethnic minorities as potential hematopoietic stem cell donors, there have been no systematic investigations of whether donor characteristics that might be linked to the donation experience vary by ethnicity.
  
  
  METHODS
  Questionnaires assessing four domains-demographic, volunteer-related, general psychosocial, and donation-related-were mailed to potential donors after they were contacted as a preliminary match for a patient and had agreed to donate. In all, 1,679 potential donors completed and returned a predonation questionnaire. Data from potential donors belonging to five major ethnic groups were analyzed; white, black, Asian/Pacific Islander, Hispanic, and Native American.
  
  
  RESULTS
  Bivariate analyses indicated that virtually all factors in the four domains were associated with ethnicity. Direct discriminant function analysis identified three significant functions. The most striking of the three functions indicated that Asian Americans were more highly educated, more ambivalent (reluctant about donation), more concerned (medical, work/family), and more anxious and depressed than all other ethnic groups. Key differences among other ethnic group members were also identified.
  
  
  CONCLUSIONS
  This study provides the first evidence of ethnic group differences in key predonation variables. Findings suggest that Asian/Pacific Islanders possess a number of characteristics that are known psychosocial risk factors for less positive postdonation outcomes and that more intensive pre and postdonation contact with this group may be necessary. Strategies for improving future research in this area are discussed.
authors.affiliation: Center for Research on Health Care, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. SwitzerGE@upmc.edu
authors.forename: Galen E
authors.initials: GE
authors.lastname: Switzer
authors.forename: Mary Amanda
authors.initials: MA
authors.lastname: Dew
authors.forename: Donna J
authors.initials: DJ
authors.lastname: Harrington
authors.forename: Megan
authors.initials: M
authors.lastname: Crowley-Matoka
authors.forename: Larissa
authors.initials: L
authors.lastname: Myaskovsky
authors.forename: Linda
authors.initials: L
authors.lastname: Abress
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Confer
mesh_terms: D005006:Ethnicity / Q000193:education / Q000523:psychology*; D018380:Hematopoietic Stem Cell Transplantation / Q000208:ethnology* / Q000523:psychology; D006801:Humans; D019520:Living Donors / Q000523:psychology*; D011795:Surveys and Questionnaires