Effect of kindling on GABAergic neurons of the hippocampus and pyriform cortex.
GABAergic neurons in different fields of the hippocampus and pyriform cortex were examined 2 weeks and 1 month after electric stimulation of the ventral hippocampus. The counts of GABAergic neurons in the studied structures decreased significantly. The most pronounced shifts in the pyriform cortex were found in the central compartment. Decreased number of inhibitory elements in the two major epileptogenic structures attests to appreciable restructuring in the functions of their neuronal circles.
Zhvaniya
M G
MG
Chemical Neuroanatomy Group, I. S. Beritashvili Institute of Physiology, Academy of Sciences of Georgia, Tbilisi. sxgeorgia@igmaxi.org
Bolkvadze
T A
TA
Dzhaparidze
N D
ND
Solomoniya
R O
RO
Kuchiashvili
N
N
D000818:Animals; D004558:Electric Stimulation; D006624:Hippocampus / Q000166:cytology*; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D009833:Olfactory Pathways / Q000166:cytology*; D051381:Rats; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D005680:gamma-Aminobutyric Acid