title: Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from phosphopeptides.
abstract: Lanthanide ions can mediate both phosphomonoester hydrolysis and beta-elimination of inorganic phosphate from polypeptide substrates under near-physiological conditions of pH, temperature, and salt.
authors.affiliation: Department of Chemistry, Yale University, New Haven, CT 06520-8107, USA.
authors.forename: Nathan W
authors.initials: NW
authors.lastname: Luedtke
authors.forename: Alanna
authors.initials: A
authors.lastname: Schepartz
mesh_terms: D000577:Amides / Q000737:chemistry; D000595:Amino Acid Sequence; D004951:Esterification; D006868:Hydrolysis; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008969:Molecular Sequence Data; D009711:Nucleotides / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry*; D010748:Phosphopeptides / Q000737:chemistry*; D010766:Phosphorylation
chemical_list: D000577:Amides; D028581:Lanthanoid Series Elements; D009711:Nucleotides; D010710:Phosphates; D010748:Phosphopeptides