title: Complete suppression of paroxysmal nonkinesigenic dyskinesia by globus pallidus internus pallidal stimulation.
abstract: Stereotactic functional surgery is being explored as potential therapies for medically intractable paroxysmal dyskinesias (PxD). We report on a 59-year-old man in whom stimulation of globus pallidus internus produced immediate and sustained relief of paroxysmal non-kinesigenic dyskinesia secondary to a rotator cuff tears on the left shoulder. Our finding strongly suggests that altered function of neuronal circuits of the basal ganglia underlies the manifestation of PxD.
authors.affiliation: Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Japan. yamadakazu@fc.kuh.kumamoto-u.ac.jp
authors.forename: Kazumichi
authors.initials: K
authors.lastname: Yamada
authors.forename: Satoshi
authors.initials: S
authors.lastname: Goto
authors.forename: Naohiro
authors.initials: N
authors.lastname: Soyama
authors.forename: Osamu
authors.initials: O
authors.lastname: Shimoda
authors.forename: Mareina
authors.initials: M
authors.lastname: Kudo
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kuratsu
authors.forename: Nagako
authors.initials: N
authors.lastname: Murase
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kaji
mesh_terms: D002819:Chorea / Q000473:pathology / Q000628:therapy*; D004599:Electric Stimulation Therapy / Q000379:methods*; D004576:Electromyography / Q000379:methods; D005917:Globus Pallidus / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged