title: Echocardiographic Doppler assessment of the biophysical properties of the aorta in pediatric patients with the Marfan syndrome.
abstract: In the Marfan syndrome (MS), aortic root involvement is usually clinically monitored according to the aortic sinus of Valsalva dilation. Using an echocardiographic Doppler method in this cross-sectional study, abnormal biophysical properties of the ascending aorta were found in pediatric patients with MS compared with healthy controls but not consistently in association with the aortic sinus of Valsalva dilation.
authors.affiliation: Division of Cardiology, Department of Pediatrics, British Columbia Children's Hospital and The University of British Columbia, Vancouver, British Columbia, Canada. timothy.bradley@sickkids.ca
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Bradley
authors.forename: James E
authors.initials: JE
authors.lastname: Potts
authors.forename: Mary T
authors.initials: MT
authors.lastname: Potts
authors.forename: Astrid M
authors.initials: AM
authors.lastname: DeSouza
authors.forename: George G S
authors.initials: GG
authors.lastname: Sandor
mesh_terms: D000293:Adolescent; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology*; D002648:Child; D003430:Cross-Sectional Studies; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015588:Observer Variation; D015203:Reproducibility of Results; D012850:Sinus of Valsalva / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014655:Vascular Resistance / Q000502:physiology*