title: Phakic intraocular lenses.
abstract: An analytical review of the data available in the field of phakic intraocular lens implantation was conducted. Particular attention was paid to the more critical issues of intraocular lens sizing and safety guidelines. A comprehensive, competitive analysis of different implantation sites, intraocular lens model designs, and safety guidelines has been included. Specialized biometry techniques, such as very high frequency ultrasound and Scheimpflug imaging, have been reviewed, and a critical review of commercial claims regarding intraocular lens technologies has been included. Clinical studies of phakic intraocular lenses demonstrate increasing promise for the correction of refractive errors not amenable to mainstream excimer laser refractive surgery. The main issues currently revolve around adequate lens design (VHF ultrasound study suggests that custom-design and sizing may be the most effective and safest approach for every phakic IOL model), because these devices will be required to remain physiologically inert and anatomically compatible with internal ocular structures and relations for several decades. The possibility of safe removing or exchanging the IOL should remain a feasible option over time. It is of utmost importance that we continue to critically evaluate current encouraging short-term outcomes, which are being extrapolated to the longer term by ongoing high resolution imaging and monitoring of the anatomical and functional relations of implanted phakic IOLs.
authors.affiliation: Department of Ophthalmology and Visual Sciences, San Raffaele Hospital and QuattroElle Eye Center, Milan, Italy, and Department of Ophthalmology, St. Thomas Hospital-Kings College, London, UK. loviseye@fastwebnet.it
authors.forename: Carlo F
authors.initials: CF
authors.lastname: Lovisolo
authors.forename: Dan Z
authors.initials: DZ
authors.lastname: Reinstein
mesh_terms: D006801:Humans; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000502:physiology*; D007910:Lenses, Intraocular; D011474:Prosthesis Design; D012029:Refraction, Ocular; D012030:Refractive Errors / Q000503:physiopathology; D054140:Refractive Surgical Procedures; D016896:Treatment Outcome