Guillain-Barre syndrome occurring after adjuvant chemo-radiotherapy for endometrial cancer.
BACKGROUND
The association between Guillain-Barre syndrome (GBS) and malignancy is uncommon and has not been previously reported in gynecological cancers.


METHODS
Our case documents this syndrome occurring in a patient shortly after completion of adjuvant chemo-radiotherapy for endometrial carcinoma. We review the current literature and discuss potential pathogenic mechanisms of this likely paraneoplastic association.


CONCLUSIONS
GBS in cancer patients is a potentially life-threatening condition and should be differentiated from simple chemotherapy toxicity, particularly as effective treatment is available.
Tho
L M
LM
Department of Clinical Oncology, Beatson Oncology Centre, Dumbarton Road, Glasgow G11 6NT, UK. Lye.Mun.Tho@NorthGlasgow.Scot.NHS.UK
O'Leary
C P
CP
Horrocks
I
I
Al-Ani
A
A
Reed
N S
NS
D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000150:complications* / Q000628:therapy; D005260:Female; D020275:Guillain-Barre Syndrome / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications*; D018714:Radiotherapy, Adjuvant