[The effect of low magnetic field on select parameters of blood coagulation].
Low frequency magnetic field causes the biological effects in organisms--in individual systems and organs.


OBJECTIVE
The purpose of our study is to analyse the influence of the low magnetic field used in magnetotherapy on prothrombin time, factor Xa activity and level of platelets in experimental animals.


METHODS
The examination was carried out on rats which were subjected to the activity of low magnetic field. The examination of prothrombin time in Quick's method (the international normalized ratio--INR was counted), activity of factor Xa by spectrophotometric method (lambda = 405 nm) were performed. The level of platelets before and after 14, 28 days of the exposition of magnetic field and after 21 days of exposure to magnetic field was assessed.


RESULTS
The extension of prothrombin time (a decrease of INR), decrease activity of factor Xa and decrease platelets level was observed in experimental animals after the exposure to low magnetic field (p < 0.05 for all examined parameters).


CONCLUSIONS
Low magnetic field used in magnetotherapy causes the changes in blood coagulation of experimental animals.
Ciejka
Elzbieta
E
Katedra Fizjologii Doświadczalnej i Klinicznej, Zakład Fizjologii Krazenia Uniwersytetu Medycznego, Lodzi. elzbietareh@interia.pl
Goraca
Anna
A
Michalska
Marta
M
Kostka
Barbara
B
D000818:Animals; D001777:Blood Coagulation / Q000528:radiation effects*; D001792:Blood Platelets / Q000528:radiation effects*; D004574:Electromagnetic Fields; D015951:Factor Xa / Q000528:radiation effects*; D010976:Platelet Count; D011517:Prothrombin Time; D051381:Rats; D017208:Rats, Wistar; D013053:Spectrophotometry
D015951:Factor Xa