title: Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides.
abstract: A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an equation which is a rational function of degree 2:3 and 2:2, respectively.
authors.affiliation: Department of Biophysics, Institute of Experimental Physics, University of Warsaw, Warsaw, Poland.
authors.forename: Kinga
authors.initials: K
authors.lastname: Banach
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Bojarska
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Kazimierczuk
authors.forename: Lucyna
authors.initials: L
authors.lastname: Magnowska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Bzowska
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives / Q000737:chemistry; D055598:Chemical Phenomena; D002621:Chemistry; D006863:Hydrogen-Ion Concentration; D020128:Inhibitory Concentration 50; D007700:Kinetics; D008962:Models, Theoretical; D010100:Oxygen / Q000737:chemistry*; D011684:Purine Nucleosides / Q000737:chemistry*; D012044:Regression Analysis; D019820:Xanthine / Q000737:chemistry; D014969:Xanthine Oxidase / Q000737:chemistry*
chemical_list: D011684:Purine Nucleosides; C069484:2-chloroadenine; D019820:Xanthine; D014969:Xanthine Oxidase; D000225:Adenine; D010100:Oxygen