Early onset of oral aphthous ulcers with weekly docetaxel.
Two patients with metastatic breast cancer developed oral aphthous ulcers after only two administrations of weekly docetaxel without any other toxicity. A treatment delay and dose reduction appears to be an effective management strategy.
G Oumlker
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Department of Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, the Netherlands. e.goker@lumc.nl
Rodenhuis
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D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013281:Stomatitis, Aphthous / Q000139:chemically induced* / Q000188:drug therapy; D043823:Taxoids / Q000009:adverse effects*
D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel