Synthesis of 2'-C-methyl-4'-thio ribonucleosides.
Starting from 2-C-methyl-ribonolactone, 1,2,3,5-tetra-O-acetyl-2-C-methyl-4-thioribofuranose was synthesized and condensed with heterocyclic bases to afford 2-C-methyl-4'-thioribonucleosides.
Dukhan
D
D
Laboratoire Coopératif Idenix-CNRS, Université Montpellier II, Montpellier Cedex 5, France.
Bosc
E
E
Peyronnet
J
J
Storer
R
R
Gosselin
G
G
D000998:Antiviral Agents / Q000494:pharmacology; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D008956:Models, Chemical; D009705:Nucleosides / Q000737:chemistry; D012328:RNA Viruses / Q000235:genetics; D013872:Thionucleosides / Q000138:chemical synthesis / Q000737:chemistry*
D000998:Antiviral Agents; D009705:Nucleosides; D013872:Thionucleosides; D003841:Deoxycytidine; C055031:2'-methyl-2'-deoxycytidine