title: Moyamoya disease--diagnosis and treatment: indirect cerebral revascularization at the Sheba Medical Center.
abstract: Moyamoya disease is a cerebral vasculopathy characterized mainly by progressive narrowing of the major intracranial vessels. While more common and having a familial predilection in the Far East, it can also develop in association with some common hereditary diseases and can be acquired after environmental exposure. In the young its manifestations are the result of cerebral ischemia. Adults usually suffer from repeated incidents of intracerebral hemorrhage. Surgical revascularization of ischemic cerebral territories plays a major role in their treatment. We review the literature and present our series of three adult and five pediatric patients; these patients were diagnosed at our institution and treated with indirect revascularization techniques.
authors.affiliation: Department of Neurosurgery, Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Ouzi
authors.initials: O
authors.lastname: Nissim
authors.forename: Matti
authors.initials: M
authors.lastname: Bakon
authors.forename: Bruria
authors.initials: B
authors.lastname: Ben Zeev
authors.forename: Elinor
authors.initials: E
authors.lastname: Goshen
authors.forename: Nachshon
authors.initials: N
authors.lastname: Knoller
authors.forename: Moshe
authors.initials: M
authors.lastname: Hadani
authors.forename: Zeev
authors.initials: Z
authors.lastname: Feldman
mesh_terms: D000328:Adult; D002548:Cerebral Revascularization / Q000009:adverse effects / Q000379:methods*; D002648:Child; D005260:Female; D006801:Humans; D007557:Israel; D008297:Male; D009072:Moyamoya Disease / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery