title: [Experimental assessment of the capacities of use of photosense. Communication 1. Fluorescence diagnosis of epibulbar and choroid tumors].
abstract: Whether Photosense (PS) may be used in the fluorescence diagnosis (FD) of experimental epibulbar and choroid tumors is discussed. The fluorescent ability of Photosense in FD permits detection of advanced malignancies. The kinetics of concentration of PS and the selectivity of its accumulation in malignant versus normal tissues were investigated. PS is shown to be an effective photosensitizer in the FD and, possibly, photodynamic therapy of tumors.
authors.forename: M V
authors.initials: MV
authors.lastname: Budzinskaia
authors.forename: V G
authors.initials: VG
authors.lastname: Likhvantseva
authors.forename: S A
authors.initials: SA
authors.lastname: Shevchik
authors.forename: V B
authors.initials: VB
authors.lastname: Loshchenov
authors.forename: S G
authors.initials: SG
authors.lastname: Kuz'min
authors.forename: G N
authors.initials: GN
authors.lastname: Vorozhtsov
mesh_terms: D000818:Animals; D002830:Choroid Neoplasms / Q000175:diagnosis*; D004596:Electroretinography; D005134:Eye Neoplasms / Q000175:diagnosis*; D005456:Fluorescent Dyes; D007211:Indoles / Q000493:pharmacokinetics; D008297:Male; D008546:Melanoma, Experimental / Q000175:diagnosis*; D009942:Organometallic Compounds / Q000493:pharmacokinetics; D011817:Rabbits; D012984:Software
chemical_list: D005456:Fluorescent Dyes; D007211:Indoles; D009942:Organometallic Compounds; C048577:aluminum tetrasulfophthalocyanine