Autoimmune thrombocytopenic purpura after mumps infection.
Autoimmune thrombocytopenic purpura is estimated to be one of the most common acquired bleeding disorders of children. The pathogenesis involves the generation of autoantibodies against the normally expressed glycoproteins on the platelet membranes. These antibody-coated platelets in turn are destroyed by the spleen and other reticuloendothelial organs. Although the disease can occur without an identifiable etiology, many underlying pathologies, including infections, can be found. We report the mumps virus as a rare etiology of secondary autoimmune thrombocytopenic purpura.
Unal
Sule
S
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Yetgin
Sevgi
S
Kara
Ateş
A
Kanra
Güler
G
D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007223:Infant; D009107:Mumps / Q000150:complications*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000209:etiology*
D016756:Immunoglobulins, Intravenous