title: [Physical activity].
abstract: There are a total of 30 publications regarding the role physical exercise in primary prevention of coronary artery disease, nearly a quarter of a million patients have participated in these studies. The average observation time reaches 10 years. According to the guidelines of the ACC/AHA Task Force this is the basis for the evidence/recommendation class I. The benefit derived from this treatment considerably exceeds the risk; thus, there is no need for additional studies. A great number of population-based risk factors were evaluated; in several randomized studies and meta-analyses concordant results were achieved with respect to direction and degree of the therapeutic effect (Level B).
authors.affiliation: Innere Medizin/Kardiologie, Herzzentrum, Universitätsklinikum Leipzig, Strümpellstrasse 39, 04289 Leipzig, Germany. schug@medizin.uni-leipzig.de
authors.forename: G
authors.initials: G
authors.lastname: Schuler
mesh_terms: D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000401:mortality* / Q000517:prevention & control*; D005081:Exercise Therapy / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D009043:Motor Activity; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016896:Treatment Outcome