title: Probing dipeptide trans/cis stereochemistry using pH control of thiopeptide analogues, and application to the PepT1 transporter.
abstract: The stereochemistry of thiodipeptides of proline [e.g. Ala-Psi[CS-N]-Pro] can be controlled using pH, allowing the trans-preference for substrates of the peptide transporter PepT1 to be confirmed.
authors.affiliation: School of Chemistry, Faraday Building, The University of Manchester, Manchester, UKM60 1QD. pat.bailey@manchester.ac.uk
authors.forename: Patrick D
authors.initials: PD
authors.lastname: Bailey
authors.forename: C A Richard
authors.initials: CA
authors.lastname: Boyd
authors.forename: Ian D
authors.initials: ID
authors.lastname: Collier
authors.forename: George L
authors.initials: GL
authors.lastname: Kellett
authors.forename: David
authors.initials: D
authors.lastname: Meredith
authors.forename: Keith M
authors.initials: KM
authors.lastname: Morgan
authors.forename: Rachel
authors.initials: R
authors.lastname: Pettecrew
authors.forename: Richard A
authors.initials: RA
authors.lastname: Price
mesh_terms: D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D026901:Membrane Transport Proteins / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D026901:Membrane Transport Proteins; D010455:Peptides; D013438:Sulfhydryl Compounds