title: Exploiting the dual reactivity of o-isocyanobenzamide: three-component synthesis of 4-imino-4H-3,1-benzoxazines.
abstract: [reaction: see text] A multicomponent synthesis of 4-imino-4H-3,1-benzoxazines is developed. Heating a toluene solution of an aldehyde (6), an amine (7), and an isonitrile (5) in the presence of a stoichiometric amount of ammonium chloride at 60 degrees C for 12 h produces the title compound in good to excellent yields.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Bonne
authors.forename: Mouloud
authors.initials: M
authors.lastname: Dekhane
authors.forename: Jieping
authors.initials: J
authors.lastname: Zhu