Nanoparticle delivery by controlled bacteria.
We present a new approach for nano-object directional delivery by bacteria based upon a taxis-controlled mechanism. In this method, a stimulus is used to direct the bacteria's motion. When carrying nano-objects, the bacteria demonstrated the ability to deliver the "loads" to targets where the stimulus is positioned. The scheme of using taxis for targeted delivery may hold a promising future for a new route to bridge nanotechnology and biotechnology.
Diao
J J
JJ
The George Washington University, Washington, DC 20052, USA.
Hua
Dong
D
Lin
Jinqun
J
Teng
H Henry
HH
Chen
Dechang
D
D002633:Chemotaxis / Q000502:physiology; D016503:Drug Delivery Systems / Q000379:methods*; D004705:Endocytosis / Q000502:physiology; D004926:Escherichia coli / Q000737:chemistry* / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D005947:Glucose / Q000494:pharmacology; D008846:Micromanipulation / Q000379:methods*; D009038:Motion; D036103:Nanotechnology / Q000379:methods*; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure*
D005947:Glucose