title: Is malaria a predisposing factor for third molar pericoronitis in the tropics?
abstract: BACKGROUND
  Malaria is an important disease in the tropics, and its role as a predisposing factor or co morbidity has been investigated in many diseases including HIV infection and tuberculosis. There are very few studies, which have investigated its role in oral and dental diseases. Our study aimed to demonstrate the possible role of malaria in predisposing to pericoronitis, an infection affecting impacted third molars predominantly.
  
  
  METHODS
  Thirty-eight patients presenting with pericoronitis were tested for malaria parasites and results compared with that obtained from controls that were equally susceptible to pericoronitis but did not have the infection.
  
  
  RESULTS
  19.7% of the study group compared to 6.6% of control group had malaria parasite in their blood. This difference was statistically significant, P=0.018 (Fisher's exact). The odds ratio was 4.3 (95% CI=1.2-17.0).
  
  
  CONCLUSIONS
  Malaria appears to be a predisposing factor to pericoronitis in this study. There is a need for further studies on the possible role of malaria in oral and dental diseases.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University, Ile-Ife 220005, Nigeria. folu_owotade@yahoo.com
authors.forename: Foluso J
authors.initials: FJ
authors.lastname: Owotade
authors.forename: Kehinde E
authors.initials: KE
authors.lastname: Adebiyi
authors.forename: Oladipo A
authors.initials: OA
authors.lastname: Aboderin
authors.forename: Olawunmi A
authors.initials: OA
authors.lastname: Fatusi
authors.forename: Eyitope O
authors.initials: EO
authors.lastname: Ogunbodede
authors.forename: Okechukwu
authors.initials: O
authors.lastname: Akueme
mesh_terms: D000328:Adult; D001769:Blood / Q000469:parasitology; D015984:Causality; D005260:Female; D006801:Humans; D008288:Malaria / Q000150:complications* / Q000469:parasitology; D008297:Male; D008964:Molar, Third / Q000469:parasitology*; D010497:Pericoronitis / Q000209:etiology*; D014095:Tooth, Impacted / Q000150:complications; D014329:Tropical Climate