Binding of alpha-1-acid glycoprotein to imatinib following increased dosage of drug.
Smith
Kevin D
KD
Paterson
Sarah
S
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000097:blood*; D001549:Benzamides; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood / Q000188:drug therapy; D009961:Orosomucoid / Q000378:metabolism*; D010879:Piperazines / Q000008:administration & dosage / Q000097:blood*; D011485:Protein Binding; D047428:Protein Kinase Inhibitors / Q000008:administration & dosage / Q000097:blood*; D011743:Pyrimidines / Q000008:administration & dosage / Q000097:blood*
D000970:Antineoplastic Agents; D001549:Benzamides; D009961:Orosomucoid; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate