title: Comparative conformational analysis of nucleosides by NMR, X-ray, and semi-empirical (PM3 VS. AM1) methods.
abstract: The 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl ortho-aza-purine and -pyrimidine nucleosides manifest an unusually rigid sugar N conformation in solution.
authors.affiliation: Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, Kuopio 70211, Finland.
authors.forename: Igor A
authors.initials: IA
authors.lastname: Mikhailopulo
authors.forename: Yuri A
authors.initials: YA
authors.lastname: Sokolov
authors.forename: Junlin
authors.initials: J
authors.lastname: He
authors.forename: Padmaja
authors.initials: P
authors.lastname: Chittepu
authors.forename: Helmut
authors.initials: H
authors.lastname: Rosemeyer
authors.forename: Frank
authors.initials: F
authors.lastname: Seela
mesh_terms: D001087:Arabinonucleosides / Q000737:chemistry; D055592:Biophysical Phenomena; D001703:Biophysics; D002241:Carbohydrates / Q000737:chemistry; D018360:Crystallography, X-Ray / Q000379:methods; D004247:DNA / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008956:Models, Chemical; D008967:Molecular Biology / Q000379:methods; D008968:Molecular Conformation; D009690:Nucleic Acid Conformation; D009711:Nucleotides / Q000737:chemistry*; D012313:RNA / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D001087:Arabinonucleosides; D002241:Carbohydrates; D009711:Nucleotides; D012313:RNA; D004247:DNA