title: Application of measurements of transepithelial electrical resistance of intestinal epithelial cell monolayers to evaluate probiotic activity.
abstract: Among five potentially probiotic lactobacilli investigated, Lactobacillus plantarum MF1298 and Lactobacillus salivarius DC5 showed the highest increase in the transepithelial electrical resistance (TER) of polarized monolayers of Caco-2 cells, and this increase was shown to be dose dependent. Furthermore, preincubation with MF1298 attenuated a decrease in TER induced by Listeria monocytogenes.
authors.affiliation: The Royal Veterinary and Agricultural University, Department of Food Science, Rolighedsvej 30, 4th Floor, DK-1958 Frederiksberg C, Denmark. tdk@kvl.dk
authors.forename: Trine Danø
authors.initials: TD
authors.lastname: Klingberg
authors.forename: Maja Herold
authors.initials: MH
authors.lastname: Pedersen
authors.forename: Avrelija
authors.initials: A
authors.lastname: Cencic
authors.forename: Birgitte Bjørn
authors.initials: BB
authors.lastname: Budde
mesh_terms: D018938:Caco-2 Cells; D016764:Cell Polarity; D017097:Electric Impedance; D004847:Epithelial Cells / Q000382:microbiology / Q000502:physiology*; D006801:Humans; D007422:Intestines / Q000166:cytology / Q000382:microbiology*; D007778:Lactobacillus / Q000254:growth & development / Q000502:physiology*; D008089:Listeria monocytogenes / Q000472:pathogenicity*; D019936:Probiotics / Q000378:metabolism*