[Experimental assessment of the capacities of use of photosense. Communication 2. Photodynamic therapy for epibulbar and choroid tumors].
The study was undertaken to evaluate the efficiency of photodynamic therapy of pigmented choroid and epibulbar melanoma, by using the agent Photosense. Pigmented choroid and epibulbar melanoma were identified in 50 rabbit eyes. After intravenous injection of Photosense, 0.7 mg/kg, the tumors were irradiated at 675 nm with an argon-pumped dye laser at 150 J/cm2. Photodynamic therapy with Photosense may be effective in treating pigmented choroid and epibulbar melanomas.
Budzinskaia
M V
MV
Likhvantseva
V G
VG
Shevxchik
S A
SA
Loshchenov
V B
VB
Kuz'min
S G
SG
Vorozhtsov
G N
GN
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002830:Choroid Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D003131:Combined Modality Therapy; D005134:Eye Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D005456:Fluorescent Dyes / Q000627:therapeutic use*; D007211:Indoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007275:Injections, Intravenous; D053685:Laser Therapy; D008297:Male; D008546:Melanoma, Experimental / Q000188:drug therapy* / Q000532:radiotherapy; D008962:Models, Theoretical; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D011817:Rabbits; D013997:Time Factors
D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D007211:Indoles; D009942:Organometallic Compounds; D017319:Photosensitizing Agents; C048577:aluminum tetrasulfophthalocyanine