title: HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic.
abstract: Thirty-eight of 175 (21.7%) consecutive women of childbearing age from a rural area near Bangassou were tested HIV-positive. Ten protease and two protease/reverse transcriptase sequences (31.5% samples) were obtained. Eight sequences clustered into subtype J, A, G; two sequences were 13_cpx recombinant forms and two were indeterminate. The high proportion of HIV found suggests a recent outbreak of diversified HIV strains.
authors.affiliation: Clinic of Infectious Diseases, University of Bari, Bari, Italy.
authors.forename: Grazia
authors.initials: G
authors.lastname: Punzi
authors.forename: Annalisa
authors.initials: A
authors.lastname: Saracino
authors.forename: Gaetano
authors.initials: G
authors.lastname: Brindicci
authors.forename: Teresa
authors.initials: T
authors.lastname: Scarabaggio
authors.forename: Antonella
authors.initials: A
authors.lastname: Lagioia
authors.forename: Gioacchino
authors.initials: G
authors.lastname: Angarano
authors.forename: Laura
authors.initials: L
authors.lastname: Monno
mesh_terms: D000293:Adolescent; D000328:Adult; D002488:Central African Republic / Q000453:epidemiology; D005260:Female; D014644:Genetic Variation; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D016333:HIV Protease / Q000235:genetics*; D054303:HIV Reverse Transcriptase / Q000235:genetics*; D015497:HIV-1 / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D010802:Phylogeny; D011247:Pregnancy
chemical_list: D054303:HIV Reverse Transcriptase; D016333:HIV Protease