title: [Morphopathological study in age related macular degeneration].
abstract: The aim of this paper is to study the morphopathological changes manifested in age-related macular degeneration.
  
  
  METHODS
  The researched histopathological material consisted in two eye balls enucleated because of irreversible eye diseases from aged persons suffering from age-related macular degeneration. The method applied for processing the material was inclusion in paraffin, followed by usual coloration with hematoxylin-eosin.
  
  
  CONCLUSIONS
  The established changes (hard drusen, soft drusen, calcified drusen, changes of Bruch's membrane, subretinal neovascularization, serous retinal pigment epithelial detachment, disciform degeneration) prove the importance of Bruch's membrane in the pathogenesis of age-related macular degeneration.
authors.affiliation: Disciplina Morfopatologie, UMF Craiova.
authors.forename: Cristiana
authors.initials: C
authors.lastname: Simionescu
authors.forename: Carmen
authors.initials: C
authors.lastname: Birău
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016570:Bruch Membrane / Q000473:pathology; D006801:Humans; D008268:Macular Degeneration / Q000473:pathology*; D008853:Microscopy; D015593:Retinal Drusen / Q000473:pathology; D015861:Retinal Neovascularization / Q000473:pathology