Efficient oxidizing agents for determination of 2,10-disubstituted phenothiazines.
2,10-Disubstituted phenothiazines are the best drugs in psychiatry. Several methods for their analysis have been reported in the literature. The official methods are based on non-aqueous titration or spectrophotometry. Various oxidizing agents have been used for the spectrophotometric determination of 2,10-disubstituted phenothiazines, e.g. Ce(SO4)2, NH4VO3, K2S208, KIO4, KIO3, KBrO3, FeCl3, NaNO2, H2O2, chloramine T, p-benzoquinone, N-bromosuccinimide. Oxidation reactions of phenothiazines were also used for their determination by flow-injection methods.
Puzanowska-Tarasiewicz
Helena
H
Institute of Chemistry, University of Białystok, Hurtowa 1 Bialystok 15-399, Poland.
Kuźmicka
Ludmiła
L
Karpińska
Joanna
J
Mielech-Lukasiewicz
Katarzyna
K
D014150:Antipsychotic Agents / Q000032:analysis / Q000737:chemistry; D017022:Flow Injection Analysis / Q000379:methods*; D016877:Oxidants / Q000737:chemistry* / Q000494:pharmacology; D010084:Oxidation-Reduction; D010640:Phenothiazines / Q000032:analysis* / Q000737:chemistry* / Q000378:metabolism; D013053:Spectrophotometry / Q000379:methods*
D014150:Antipsychotic Agents; D016877:Oxidants; D010640:Phenothiazines