title: Systemic lupus erythematosus - associated acute severe thrombocytopenia and leukopenia first presented in pregnancy.
abstract: We report a rare case of acute severe thrombocytopenia and leukopenia, which first presented at 37 weeks' gestation. Based on clinical as well as on laboratory findings the diagnosis of systemic lupus erythematosus was made. The patient was successfully managed with an emergency transfusion of 6 units of platelets and intravenous immunoglobulin infusion followed by methylprednisolone administration. A caesarean section was performed at 39 weeks. The neonate was not thrombocytopenic at birth, nor at the age of 1 month.
authors.affiliation: 1st Department of Obstetrics and Gynaecology, University of Athens, Athens, Greece. gdaskalakis@yahoo.com
authors.forename: G
authors.initials: G
authors.lastname: Daskalakis
authors.forename: N
authors.initials: N
authors.lastname: Papantoniou
authors.forename: S
authors.initials: S
authors.lastname: Marinopoulos
authors.forename: E
authors.initials: E
authors.lastname: Vomvolaki
authors.forename: I
authors.initials: I
authors.lastname: Papageorgiou
authors.forename: S
authors.initials: S
authors.lastname: Mesogitis
authors.forename: A
authors.initials: A
authors.lastname: Antsaklis
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007970:Leukopenia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D017713:Platelet Transfusion; D011247:Pregnancy; D011248:Pregnancy Complications; D011250:Pregnancy Complications, Hematologic; D011256:Pregnancy Outcome; D013921:Thrombocytopenia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone