Radiographic progression in rheumatoid arthritis.
Radiographic progression is an important outcome measure in clinical trials and observational studies with patients with rheuamtoid arthritis. In this article we describe several aspects of measuring radiographic progression. We introduce the scoring method, discuss scoring methodology and issues regarding reliability of scoring, describe the relation between disease activity, radiographic progression and physical function, and introduce the concept of repair, a novelty in the field of measuring structural changes in RA.
Landewé
Robert
R
University Hospital Maastricht, Department Internal Medicine/Rheumatology, P.O. Box 5800, 6202AZ Maastricht, The Netherlands. RLAN@SINT.AZM.NL
van der Heijde
Désirée
D
D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001175:Arthrography; D004185:Disability Evaluation; D018450:Disease Progression; D006801:Humans; D007596:Joints / Q000503:physiopathology; D015203:Reproducibility of Results; D012219:Rheumatology / Q000379:methods*