[Palliative options for esophageal carcinoma].
Considering the limited chances of radically curing esophageal carcinoma, most of these patients are candidates for palliative therapy. Priority should be given to rapid relief of dysphagia. Endoscopic implantation of esophageal prostheses is immediately effective in 90% of patients, whereas the onset of relief is slower with any alternative method. Long-term complications necessitate an endoscopic reintervention in 30% of the prosthesis carriers. Endoscopic prosthesis implantation is also the first-choice treatment for esophagotracheal fistulae. Self-expanding stents need only minimized preceding bougienage, which has lower complication rates than conventional plastic prostheses. Endoscopic laser radiation is better tolerated by patients than prosthesis implantation but is effective only in very short stenoses. Endoluminal brachytherapy with (192)iridium can be justified in patients with a survival expectancy of more than 6 months, the onset of its effect being slower but longer lasting. Palliative chemotherapy and radiochemotherapy are indicated when metastatic dissemination dominates the symptoms.
Hagenmüller
F
F
Allgemeines Krankenhaus Altona Hamburg. Friedrich.Hagenmueller@ak-altona.lbk-hh.de
D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003680:Deglutition Disorders / Q000401:mortality / Q000473:pathology / Q000628:therapy; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D004940:Esophageal Stenosis / Q000401:mortality / Q000473:pathology / Q000628:therapy; D006801:Humans; D010166:Palliative Care; D011183:Postoperative Complications / Q000401:mortality / Q000473:pathology / Q000628:therapy; D019919:Prosthesis Implantation; D018714:Radiotherapy, Adjuvant; D015607:Stents; D016019:Survival Analysis