The genetics of systemic lupus erythematosus.
For years the identification of candidate genes has been approached in various ways. The latest technology allows for whole genome SNP analysis in genetic association studies. These studies pose new challenges but also new possibilities. I hereby review what is known to date on lupus genetics and what challenges we are to overcome with the new available methods.
Alarcón-Riquelme
Marta E
ME
Department of Genetics and Pathology, Uppsala University, Dag Hammarskjölds väg 20, 751 85, Uppsala, Sweden. marta.alarcon@genpat.uu.se
D000818:Animals; D008040:Genetic Linkage; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci