title: Successful treatment of electrical storm with oral quinidine in Brugada syndrome.
abstract: A patient implanted with a cardioverter-defibrillator for symptomatic Brugada syndrome was referred to our hospital 17 months later because of recurrent shocks due to ventricular fibrillation (VF). Isoprenaline was intravenously infused and prevented VF episodes, but VF recurred after every attempt of drug discontinuation. A total of 34 shocks were recorded over 25 days. Subsequently, we treated the patient with oral quinidine and the drug suppressed the electrical storm and prevented VF episodes during a follow-up period of 3 years. This case report, together with few others reported in the literature, suggests a role of oral quinidine in the treatment of electrical storm in Brugada syndrome.
authors.affiliation: Division of Cardiology and Arrhythmologic Center, Civic Hospital, Cento (FE), Italy.
authors.forename: Katia
authors.initials: K
authors.lastname: Bettiol
authors.forename: Lorella
authors.initials: L
authors.lastname: Gianfranchi
authors.forename: Salvatore
authors.initials: S
authors.lastname: Scarfò
authors.forename: Federico
authors.initials: F
authors.lastname: Pacchioni
authors.forename: Mario
authors.initials: M
authors.lastname: Pedaci
authors.forename: Paolo
authors.initials: P
authors.lastname: Alboni
mesh_terms: D000284:Administration, Oral; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D002037:Bundle-Branch Block / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011802:Quinidine / Q000008:administration & dosage*; D012074:Remission Induction; D013577:Syndrome; D014693:Ventricular Fibrillation / Q000188:drug therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D011802:Quinidine