Stakeholder position paper: the need for antimicrobial use data for risk assessment.
Risk assessment seeks to estimate the probability and impact of human health effects due to antimicrobial resistance arising from antimicrobial use in animals. Potential ecological pathways for the flow of antimicrobial resistant bacteria and resistance determinants through the food supply and environment are diverse and complicated and this has been a logistical barrier to direct epidemiological measure of risk. Consequently, a number of indirect approaches to assessment have been developed. This paper provides some examples of risk assessments that have been conducted with and without antimicrobial use data, and identifies possible benefits and applications of quantitative antimicrobial use data for risk assessment.
McEwen
Scott A
SA
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ont., Canada N1G 2W1. smcewen@uoguelph.ca
Singer
Randall S
RS
D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003625:Data Collection / Q000706:statistics & numerical data*; D024881:Drug Resistance, Bacterial; D020387:Food Chain; D006801:Humans; D011634:Public Health; D018570:Risk Assessment; D014481:United States; D014730:Veterinary Medicine / Q000379:methods*
D000900:Anti-Bacterial Agents