title: Three-dimensional reconstruction of limited-view projections for contrast-enhanced magnetic resonance angiography at high temporal and spatial resolution.
abstract: The feasibility of reconstructing three-dimensional (3D) MRI data sets from limited-view projections is investigated in phantom and in vivo animal studies to improve the temporal resolution of magnetic resonance angiography without sacrificing spatial resolution. Thirty-two pairs of orthogonal biplane projections are acquired in an interleaved manner during the first pass of a contrast agent. The full data set is reconstructed as a priori 3D information. Each pair of projections is then reconstructed into an individual 3D data set based on a correlation analysis with the a priori data set. In this way, time-resolved 3D data sets at 1- to 2-s time intervals are reconstructed with submillimeter spatial resolution. Artifacts are limited if the image is simply structured or sparse and if SNR is sufficient in the projection images. With this technique, both high temporal and spatial resolution can be achieved simultaneously.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Canada. huangyx@sten.sunnybrook.utoronto.ca
authors.forename: Yuexi
authors.initials: Y
authors.lastname: Huang
authors.forename: David
authors.initials: D
authors.lastname: Gurr
authors.forename: Graham A
authors.initials: GA
authors.lastname: Wright
mesh_terms: D000818:Animals; D003287:Contrast Media; D004285:Dogs; D005240:Feasibility Studies; D007083:Iliac Artery / Q000033:anatomy & histology; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*
chemical_list: D003287:Contrast Media