Chromosome dynamics: actin's gone fishing.
Chromosome congression and segregation have been widely known to be coordinated by the function of the dynamic spindle microtubules. But recent work suggests that oocytes may employ a unique actin-dependent mechanism of chromosome delivery to the spindle.
Rizk
Rania S
RS
Medical Sciences, Indiana University, 915 E. 3rd St., Myers Hall 262, Bloomington, Indiana 47405, USA.
Walczak
Claire E
CE
D000199:Actins / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D019086:Bridged Bicyclo Compounds, Heterocyclic; D020090:Chromosome Segregation / Q000502:physiology*; D047630:Depsipeptides; D008954:Models, Biological; D015739:Nocodazole; D009865:Oocytes / Q000502:physiology*; D010590:Phalloidine; D008941:Spindle Apparatus / Q000502:physiology*; D013215:Starfish / Q000502:physiology*; D013844:Thiazoles; D053778:Thiazolidines
D000199:Actins; D019086:Bridged Bicyclo Compounds, Heterocyclic; D047630:Depsipeptides; D013844:Thiazoles; D053778:Thiazolidines; C057531:jasplakinolide; D010590:Phalloidine; C037068:latrunculin B; D015739:Nocodazole