A comparison of experience-dependent plasticity in the visual and somatosensory systems.
In the visual and somatosensory systems, maturation of neuronal circuits continues for days to weeks after sensory stimulation occurs. Deprivation of sensory input at various stages of development can induce physiological, and often structural, changes that modify the circuitry of these sensory systems. Recent studies also reveal a surprising degree of plasticity in the mature visual and somatosensory pathways. Here, we compare and contrast the effects of sensory experience on the connectivity and function of these pathways and discuss what is known to date concerning the structural, physiological, and molecular mechanisms underlying their plasticity.
Fox
Kevin
K
Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, United Kingdom. foxkd@cf.ac.uk
Wong
Rachel O L
RO
D000200:Action Potentials / Q000502:physiology; D000344:Afferent Pathways / Q000166:cytology / Q000502:physiology*; D000818:Animals; D006801:Humans; D007858:Learning / Q000502:physiology*; D008959:Models, Neurological; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D013003:Somatosensory Cortex / Q000166:cytology / Q000502:physiology*; D013997:Time Factors; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*