title: Efficacy of Haemate-P as prophylaxis of recurrent bleeding in a patient with type 2B von Willebrand's disease.
abstract: We report the case of a 58-year-old woman with type 2B von Willebrand's disease who received regular infusions of the factor VIII/von Willebrand factor concentrate Haemate-P (2000 IU every other day) for 4 months to prevent recurrent bleeding from a malignant esophageal ulcer. Prophylaxis with Haemate-P was shown to be safe and effective in this patient, thus enabling completion of radiochemotherapy.
authors.affiliation: Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera di Verona, Verona, Italy. mfranchini@mail.univr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Annachiara
authors.initials: A
authors.lastname: Giuffrida
authors.forename: Giorgio
authors.initials: G
authors.lastname: Gandini
mesh_terms: D004938:Esophageal Neoplasms / Q000150:complications* / Q000532:radiotherapy; D005169:Factor VIII / Q000008:administration & dosage*; D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D014842:von Willebrand Diseases / Q000150:complications* / Q000188:drug therapy; D014841:von Willebrand Factor / Q000008:administration & dosage*
chemical_list: D014841:von Willebrand Factor; C078147:F8 protein, human; D005169:Factor VIII