Novel strategy for single nucleotide polymorphism (SNP) genotyping by heteroduplex analysis: specific stabilization of TT mismatch base pair by mercury (II) cation and CC mismatch base pair by silver (I) cation.
Torigoe
Hidetaka
H
Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo, Japan. htorigoe@ch.kagu.tus.ac.jp
Kawahashi
Kouji
K
Takamori
Ayako
A
Ono
Akira
A
D020137:Base Pair Mismatch; D001665:Binding Sites; D002412:Cations; D045744:Cell Line, Tumor; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D015195:Drug Design; D005821:Genetic Techniques; D005838:Genotype; D020180:Heteroduplex Analysis / Q000379:methods*; D006801:Humans; D020128:Inhibitory Concentration 50; D008628:Mercury; D008956:Models, Chemical; D009692:Nucleic Acid Heteroduplexes / Q000737:chemistry; D020641:Polymorphism, Single Nucleotide; D012834:Silver / Q000737:chemistry; D013696:Temperature; D014466:Ultraviolet Rays
D002412:Cations; D009692:Nucleic Acid Heteroduplexes; D012834:Silver; D008628:Mercury