[Transpupillary thermotherapy for circumscribed choroidal hemangioma].
OBJECTIVE
To evaluate the efficacy of transpupillary thermotherapy (TTT) on circumscribed choroidal hemangioma.


METHODS
Ten eyes of 10 cases with circumscribed choroidal hemangioma (age 16-48, average 34.4) were included in the present study. Six cases had previous green laser (4 argon and 2 krypton) photocoagulation, TTT as a primary treatment was used for other 4 cases without previous laser application. Fluorescein angiography, visual acuity, anterior segment and fundus examination, perimetry test, FFA/ICGA and ultrasonography were performed in all patients before the treatment. One to five infra red diode laser spots (810 nm with power of 800-1200 mW, diameter of 3 mm) were delivered on the surface of tumor with 60 seconds exposure, additional 10-20 seconds exposure was used in some cases. Second treatment was given 1-3 month later if there was active leakage demonstrated by fluorescein angiography. The followed-up period was 6-36 months (averaged 14.5 month).


RESULTS
After transpupillary thermotherapy, 9 eyes (90%) showed partial regression of the tumor. Average visual acuity was 0.25 and 0.6 before and after TTT, respectively. Six patients showed improvement of vision acuity, but vision acuity in 4 patients with cystic macular degeneration remained unchanged. No recurrences were observed within follow-up averaged 14.5 months. Transpupillary thermotherapy did not associate with any significant complications.


CONCLUSIONS
Transpupillary thermotherapy is effective to treat circumscribed hemangioma of choroid either as a primary treatment or supplementary therapy to previous laser photocoagulation.
Zhang
Cheng-fen
CF
Department of Ophthalmology, Peking Union Medical College Hospital, Eye Research Center of Chinese Academy of Medical Sciences, Beijing 100730, China. zhchf888@sina.com
Dong
Fang-tian
FT
Chen
You-xin
YX
Li
Zhi-qing
ZQ
Jia
Yan
Y
Du
Hong
H
Han
Bao-ling
BL
D000293:Adolescent; D000328:Adult; D002830:Choroid Neoplasms / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D011680:Pupil; D012160:Retina / Q000473:pathology / Q000528:radiation effects; D014792:Visual Acuity; D055815:Young Adult