The role of Helicobacter pylori infection in children with acute immune thrombocytopenic purpura.
The outcome of immune thrombocytopenic purpura (ITP) is classified as acute or chronic depending on whether platelet count returns to normal. The prevalence of Helicobacter pylori infection increases with age and is independent of gender. We investigated the prevalence of H. pylori infection in Chinese children from Northern Taiwan and analyzed the association between H. pylori infection and acute ITP. Our prospective cohort studies found no statistically significant relation between H. pylori infection and acute ITP. There is therefore no indication to screen children with presumed acute ITP for H. pylori infection.
Jaing
Tang-Her
TH
Division of Hematology/Oncology, Chang Gung Children's Hospital, Taoyuan, Taiwan. jaing001@cgmh.org.tw
Tsay
Pei-Kwei
PK
Hung
Iou-Jih
IJ
Chiu
Cheng-Hsun
CH
Yang
Chao-Ping
CP
Huang
I-Anne
IA
D000208:Acute Disease; D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D007223:Infant; D008297:Male; D016555:Matched-Pair Analysis; D015995:Prevalence; D011446:Prospective Studies; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013624:Taiwan / Q000453:epidemiology