The quality of life in patients with chronic pancreatitis evaluated using the SF-12 questionnaire: a comparative study with the SF-36 questionnaire.
BACKGROUND
In clinical practice there is the need to utilise a time saving questionnaire to assess the quality of life.


OBJECTIVE
To establish the validity of the SF-12 questionnaire in chronic pancreatitis patients and to identify the predictors capable of modifying the physical and mental summaries in these patients.
SF-12 and SF-36 questionnaires were used.


METHODS
One hundred and forty-one outpatients with proven chronic pancreatitis. The data of 141 sex- and age-matched Italian subjects of two normative groups (61,434 Italian subjects for SF-12 and 2031 Italian subjects for SF-36) were used as controls.


RESULTS
Chronic pancreatitis patients had the SF-12 physical and mental component summaries significantly related to the SF-36 physical and mental component summaries (P<0.001). The presence of pancreatic pain and non-pancreatic surgery accounted for 41.3% in the formation of the PCS-36 score and 37.2% in that of the PCS-12 score, respectively. Gender, BMI and pancreatic pain accounted for 15.3% of the information in the formation of the MCS-36 and for 14.7% in that of the MCS-12; using these clinical variables, the loss of information in applying the SF-12 instead of the SF-36 was very low (4.1 and 0.6% for the PCS and the MCS, respectively).


CONCLUSIONS
The SF-12 is a good alternative to the SF-36 in assessing the quality of life in chronic pancreatitis.
Pezzilli
R
R
Department of Internal Medicine and Gastroenterology, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti, 9, Bologna 40138, Italy. pezzilli@aosp.bo.it
Morselli-Labate
A M
AM
Frulloni
L
L
Cavestro
G M
GM
Ferri
B
B
Comparato
G
G
Gullo
L
L
Corinaldesi
R
R
D000293:Adolescent; D005163:Factor Analysis, Statistical; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D050500:Pancreatitis, Chronic; D011788:Quality of Life; D011795:Surveys and Questionnaires