Crystallization on confined engineered surfaces: a method to control crystal size and generate different polymorphs.
Patterned glycine crystals nucleated on functionalized metallic square islands. This approach can be used to fabricate particles with micron dimensions and screen solid forms under different conditions. The size of the glycine crystals is controlled by the dimensions of the islands. High energy metastable beta-glycine crystallizes on small metallic islands, whereas for large islands, the polymorphic outcome becomes biased toward the alpha-form.
Lee
Alfred Y
AY
Department of Chemical and Environmental Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA.
Lee
In Sung
IS
Dette
Severine S
SS
Boerner
Jana
J
Myerson
Allan S
AS
D003460:Crystallization; D005998:Glycine / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D010316:Particle Size; D012996:Solutions / Q000737:chemistry; D013059:Spectrum Analysis, Raman
D012996:Solutions; D006046:Gold; D005998:Glycine