Complete suppression of paroxysmal nonkinesigenic dyskinesia by globus pallidus internus pallidal stimulation.
Stereotactic functional surgery is being explored as potential therapies for medically intractable paroxysmal dyskinesias (PxD). We report on a 59-year-old man in whom stimulation of globus pallidus internus produced immediate and sustained relief of paroxysmal non-kinesigenic dyskinesia secondary to a rotator cuff tears on the left shoulder. Our finding strongly suggests that altered function of neuronal circuits of the basal ganglia underlies the manifestation of PxD.
Yamada
Kazumichi
K
Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Japan. yamadakazu@fc.kuh.kumamoto-u.ac.jp
Goto
Satoshi
S
Soyama
Naohiro
N
Shimoda
Osamu
O
Kudo
Mareina
M
Kuratsu
Jun-ichi
J
Murase
Nagako
N
Kaji
Ryuji
R
D002819:Chorea / Q000473:pathology / Q000628:therapy*; D004599:Electric Stimulation Therapy / Q000379:methods*; D004576:Electromyography / Q000379:methods; D005917:Globus Pallidus / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged