Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from phosphopeptides.
Lanthanide ions can mediate both phosphomonoester hydrolysis and beta-elimination of inorganic phosphate from polypeptide substrates under near-physiological conditions of pH, temperature, and salt.
Luedtke
Nathan W
NW
Department of Chemistry, Yale University, New Haven, CT 06520-8107, USA.
Schepartz
Alanna
A
D000577:Amides / Q000737:chemistry; D000595:Amino Acid Sequence; D004951:Esterification; D006868:Hydrolysis; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008969:Molecular Sequence Data; D009711:Nucleotides / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry*; D010748:Phosphopeptides / Q000737:chemistry*; D010766:Phosphorylation
D000577:Amides; D028581:Lanthanoid Series Elements; D009711:Nucleotides; D010710:Phosphates; D010748:Phosphopeptides