title: Review and update of uncommon primary pleural tumors: a practical approach to diagnosis.
abstract: OBJECTIVE
  We address the current classifications and new changes regarding uncommon primary pleural tumors. Primary pleural tumors are divided according to their behavior and are discussed separately as benign tumors, tumors of low malignant potential, and malignant neoplasms.
  
  
  METHODS
  Current literature concerning primary pleural neoplasms was collected and reviewed.
  
  
  METHODS
  Studies emphasizing clinical, radiological, or pathologic findings of primary pleural neoplasms were obtained.
  
  
  METHODS
  Data deemed helpful to the general surgical pathologist when confronted with an uncommon primary pleural tumor was included in this review.
  
  
  RESULTS
  Tumors are discussed in 3 broad categories: (1) benign, (2) low malignant potential, and (3) malignant. A practical approach to the diagnosis of these neoplasms in surgical pathology specimens is offered. The differential diagnosis, including metastatic pleural neoplasms, is also briefly addressed.
  
  
  CONCLUSIONS
  Uncommon primary pleural neoplasms may mimic each other, as well as mimic metastatic cancers to the pleura and diffuse malignant mesothelioma. Correct diagnosis is important because of different prognosis and treatment implications for the various neoplasms.
authors.affiliation: Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Granville
authors.forename: Alvaro C
authors.initials: AC
authors.lastname: Laga
authors.forename: Timothy Craig
authors.initials: TC
authors.lastname: Allen
authors.forename: Megan
authors.initials: M
authors.lastname: Dishop
authors.forename: Victor L
authors.initials: VL
authors.lastname: Roggli
authors.forename: Andrew
authors.initials: A
authors.lastname: Churg
authors.forename: Dani S
authors.initials: DS
authors.lastname: Zander
authors.forename: Philip T
authors.initials: PT
authors.lastname: Cagle
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D008495:Medical Oncology / Q000379:methods* / Q000639:trends; D008654:Mesothelioma / Q000145:classification / Q000473:pathology* / Q000601:surgery; D009362:Neoplasm Metastasis / Q000473:pathology*; D010994:Pleura / Q000473:pathology; D010997:Pleural Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery