Restless legs syndrome and quality of sleep in type 2 diabetes.
OBJECTIVE
To investigate the presence of restless legs syndrome (RLS) and the quality of sleep in a population of type 2 diabetic patients.


METHODS
The study population was composed of 100 consecutive patients regularly attending a diabetes clinic at the University Hospital of the Federal University of Ceará. The subjects' quality of sleep was assessed by the Pittsburgh Sleep Quality Index, and excessive daytime sleepiness (EDS) was measured by the Epworth Sleepiness Scale. The RLS was diagnosed using the four minimum criteria defined by the International Restless Legs Syndrome Study Group. Other relevant clinical and laboratory parameters were obtained by interview and chart review.


RESULTS
RLS was found in 27% of patients. Poor sleep quality was present in 45% of cases and was associated with age (P = 0.04), peripheral neuropathy (P = 0.001), and RLS (P = 0.000). EDS was found in 26% of patients. Logistic regression analysis revealed an association between RLS and peripheral neuropathy (odds ratio 12.85 [95% CI 2.83-58.40], P = 0.001).


CONCLUSIONS
RLS is common in type 2 diabetic patients and can be a major cause of sleep disruption in these patients.
Lopes
Lívia A
LA
Department of Medicine, Federal University of Ceará, Ceará, Brazil.
Lins
Camila de M M
Cde M
Adeodato
Vanessa G
VG
Quental
Diana P
DP
de Bruin
Pedro F C
PF
Montenegro
Renan M
RM
de Bruin
Veralice M S
VM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D012890:Sleep; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D011795:Surveys and Questionnaires