title: Production of natural methyl anthranilate by microbial N-demethylation of N-methyl methyl anthranilate by the topsoil-isolated bacterium Bacillus megaterium.
abstract: Bacillus megaterium, isolated in a screening process from topsoil, was used for N-demethylation of natural N-methyl methyl anthranilate to produce natural methyl anthranilate. Maximal productivity of 70 mg/L/day was achieved under laboratory-scale conditions without further optimization. No byproducts were observed. Thus, production of "natural" methyl anthranilate using B. megaterium is a significant improvement over comparable already existing procedures.
authors.affiliation: Lehrstuhl für Lebensmittelchemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.
authors.forename: Marcus
authors.initials: M
authors.lastname: Taupp
authors.forename: Dag
authors.initials: D
authors.lastname: Harmsen
authors.forename: Frank
authors.initials: F
authors.lastname: Heckel
authors.forename: Peter
authors.initials: P
authors.lastname: Schreier
mesh_terms: D001410:Bacillus megaterium / Q000378:metabolism*; D008745:Methylation; D012988:Soil Microbiology; D062367:ortho-Aminobenzoates / Q000378:metabolism*
chemical_list: D062367:ortho-Aminobenzoates; C038892:methyl anthranilate