title: Assessment of coronary artery disease in hemodialysis patients with delayed systolic blood pressure response after exercise testing.
abstract: BACKGROUND
  We evaluated usefulness of the postexercise systolic blood pressure (SBP) response for detecting coronary artery disease (CAD) in hemodialysis patients.
  
  
  METHODS
  A treadmill exercise testing was done, and the SBP response was measured in 44 hemodialysis patients (30 men, 14 women; age 41 to 81 years). The postexercise SBP response was defined as the ratio of SBP after 3 minutes of recovery to SBP at peak exercise.
  
  
  RESULTS
  The SBP ratio of the 25 subjects with coronary artery stenosis (1.01+/- 0.13) was significantly greater (p<0.01) than 19 subjects without coronary artery stenosis (0.83+/- 0.10). An SBP ratio greater than 0.92 identified CAD with higher sensitivity, specificity, and accuracy than did the conventional ST-segment depression criterion (76 vs. 56%, 90 vs. 53%, and 82 vs. 55%, respectively).
  
  
  CONCLUSIONS
  Determination of the SBP ratio is a clinically useful, noninvasive method for accurately detecting CAD in hemodialysis patients.
authors.affiliation: Department of Medicine II, Kansai Medical University, Osaka, Japan. fukuim@takii.kmu.ac.jp
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Fukui
authors.forename: Yasukiyo
authors.initials: Y
authors.lastname: Mori
authors.forename: Kazuya
authors.initials: K
authors.lastname: Takehana
authors.forename: Hiroya
authors.initials: H
authors.lastname: Masaki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Motohiro
authors.forename: Norihiko
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kitamura
authors.forename: Susumu
authors.initials: S
authors.lastname: Yoshida
authors.forename: Seishi
authors.initials: S
authors.lastname: Nakamura
authors.forename: Masato
authors.initials: M
authors.lastname: Baden
authors.forename: Mitsushige
authors.initials: M
authors.lastname: Nishikawa
authors.forename: Toshiji
authors.initials: T
authors.lastname: Iwasaka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005080:Exercise Test; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis