title: Refractory severe ocular hypertension after intravitreal triamcinolone acetonide injection.
abstract: OBJECTIVE
  To report a serious complication following intravitreal triamcinolone acetonide injection.
  
  
  METHODS
  Observational case report.
  
  
  RESULTS
  In 2 patients, secondary intractable severe ocular hypertension occurred 2 months after a single 4-mg intravitreal injection of triamcinolone acetonide for macular edema. Both patients required trabeculectomy intervention to control intraocular pressure (IOP).
  
  
  CONCLUSIONS
  We highlight the occurrence of intractable high IOP elevation as a serious complication 2 months after intravitreal triamcinolone acetonide. Cautious monitoring of IOP for several months after this therapy is recommended. The risks of this potentially devastating complication need to be weighed against the benefits of intravitreal triamcinolone in the individual patient.
authors.affiliation: Department of Ophthalmology, Taipei Veterans General Hospital, Taiwan, ROC. csyang@vghtpe.gov.tw
authors.forename: Chang-Sue
authors.initials: CS
authors.lastname: Yang
authors.forename: Mei-Ju
authors.initials: MJ
authors.lastname: Chen
authors.forename: Ching-Kuang
authors.initials: CK
authors.lastname: Chou
authors.forename: Wen-Ming
authors.initials: WM
authors.lastname: Hsu
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000139:chemically induced* / Q000188:drug therapy / Q000601:surgery; D014130:Trabeculectomy; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014822:Vitreous Body
chemical_list: D000959:Antihypertensive Agents; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide