Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite.
In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H2O2. The glucose biosensor shows a linear calibration curve over the range from 1.0x10(-6) to 8.0x10(-4) mol/L, with a slope and detection limit (S/N=3) of 2.3 mA/M and 5.0x10(-7) M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5% R.S.D.) and good operational stability (over 2 weeks).
Xian
Yuezhong
Y
Department of Chemistry, East China Normal University, Shanghai 200062, PR China. yzxian@chem.ecnu.edu.cn
Hu
Yi
Y
Liu
Fang
F
Xian
Yang
Y
Wang
Haiting
H
Jin
Litong
L
D000814:Aniline Compounds; D015374:Biosensing Techniques; D005947:Glucose / Q000032:analysis*; D006046:Gold; D053761:Nanocomposites; D053758:Nanoparticles; D036103:Nanotechnology; D012680:Sensitivity and Specificity
D000814:Aniline Compounds; C416807:polyaniline; D006046:Gold; D005947:Glucose