Interface between endocrinology and psychiatry in women with epilepsy: analysis of the relationship with comorbid pathology.
This study was carried out to detect a possible association between endocrine pathology, neurological symptoms, and psychiatric variables in women with epilepsy. One hundred and thirty epileptic women with childbearing potential were recruited into the study. The results obtained showed that catamenial epilepsy was observed mainly in women with reproductive dysfunction and normal thyroid function. There was a reciprocal relationship between thyroid and reproductive pathology. Catameniality interacted with reproductive dysfunction, thyroid state, and focus laterality and determined not only the frequency of certain seizures but also psychopathological constructs of the SCL-90 scale. It was concluded that catameniality should be a topic of further research.
Kalinin
Vladimir V
VV
Department of Brain Organic Disorders and Epilepsy, Moscow Research Institute of Psychiatry, Ministry of Health, Moscow, Russia. doct.kalinin@mail.ru
Zheleznova
Elena V
EV
D000293:Adolescent; D000328:Adult; D015897:Comorbidity; D004827:Epilepsy / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D001523:Mental Disorders / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D015999:Multivariate Analysis; D010049:Ovarian Diseases / Q000150:complications*; D013959:Thyroid Diseases / Q000150:complications*; D013961:Thyroid Gland / Q000503:physiopathology