Salivary gland Basal cell adenomas--immunohistochemical evaluation of four cases and review of the literature.
OBJECTIVE
Evaluate the antigen profile of cellular population from basal cell adenomas.


METHODS
Histopathological and immunohistochemical evaluation of four-salivary gland basal cell adenomas; the pathological samples were provided by the Oral Maxilla Facial Surgery Department of the Clinical County Hospital from Craiova.


RESULTS
All basal cell adenoma exhibit differentiation toward 3 cell phenotypes: ductal luminal, basal and myoepithelial.


CONCLUSIONS
The antigen profile of these tumors closely regard with other variants of salivary gland adenomas, such as pleomorphic adenoma and myoepithelioma. So, we can conclude that these tumors had a common origin, most probably from intercalated ducts and the proportion of those 3 cellular types, their cytoarchitectural arrangements and the quantity of extracellular matrix production can do the differentiation between them.
Mărgăritescu
Cl
C
Department of Pathology, Faculty of Dentistry, University of Medicine and Pharmacy of Craiova. mclaudiu@umfcv.ro
Mercuţ
Veronica
V
Mogoantă
L
L
Florescu
Maria
M
Simionescu
Cristiana
C
Cionca
Lucia
L
Manea
Mădălina
M
D000236:Adenoma / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D008875:Middle Aged; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012468:Salivary Gland Neoplasms / Q000473:pathology*
D018809:Proliferating Cell Nuclear Antigen