Applications of capillary electrophoresis on microchip.
CE on microchip is an emerging separation technique that has attracted wide attention and gained considerable popularity. Because of miniaturization of the separation format, CE on chip typically offers shorter analysis time and lower reagent consumption with potential development of portable analytical instrumentation. This review with 143 references is focused on proteins and peptides analysis, DNA separation including fragment sizing, genotyping, mutation detection and sequencing, and also the analysis of low-molecular-weight compounds, namely explosive residues and warfare agents, pharmaceuticals and drugs of abuse, and various small molecules in body fluids.
Dolnik
Vladislav
V
Alcor BioSeparations, Santa Clara, CA 95051, USA. ladia@dolnik.net
Liu
Shaorong
S
D002846:Chromatography, Affinity; D004252:DNA Mutational Analysis; D019075:Electrophoresis, Capillary; D015180:Electrophoresis, Gel, Two-Dimensional; D007525:Isoelectric Focusing; D046228:Microarray Analysis; D011506:Proteins / Q000032:analysis / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
D011506:Proteins