title: The value of small observations in the era of big science.
authors.affiliation: Division of Molecular Medicine and Genetics, Departments of Internal Medicine, Epidemiology, and Human Genetics, 4301 MSRBIII, University of Michigan, Ann Arbor, MI 48109-0638, USA. sgruber@umich.edu
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Gruber
mesh_terms: D006801:Humans; D008545:Melanoma / Q000209:etiology / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D044102:Receptor, Melanocortin, Type 1 / Q000235:genetics*; D012107:Research Design; D012307:Risk Factors; D018401:Sample Size; D012878:Skin Neoplasms / Q000209:etiology / Q000235:genetics*
chemical_list: D044102:Receptor, Melanocortin, Type 1