Microarrays: applications and pitfalls.
Microarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very useful but they are also very misleading; better data analysis tools are needed to improve accuracy.
Fathallah-Shaykh
Hassan M
HM
Department of Neurological Sciences, Section of Neuro-oncology, Rush University Medical Center, Chicago, Ill 60612, USA. hfathall@rush.edu
D000818:Animals; D020869:Gene Expression Profiling; D006801:Humans; D046228:Microarray Analysis