The association between osteoporosis and oral bone loss.
BACKGROUND
Osteoporosis and osteopenia are characterized by reductions in bone mass and may lead to skeletal fragility and fracture. The purpose of this paper is to review studies to determine the relationship between oral bone loss and osteoporosis. In addition, the major modes of therapy for osteoporosis are discussed.


METHODS
In this convenience review, papers studying the possible correlation between oral bone loss and osteoporosis in humans, written in the English language since 1983, were reviewed.


RESULTS
The methods used to assess oral and systemic bone varied greatly from study to study. Therefore, the results were not amenable to meta-analysis. Thirteen of the 15 studies did show a positive correlation between systemic bone mass and oral bone mass (or bone loss).


CONCLUSIONS
Studies to date indicate a possible correlation between systemic and oral bone loss.
Jeffcoat
Marjorie
M
University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA. jeffcoat@dental.upenn.edu
D015502:Absorptiometry, Photon; D000367:Age Factors; D016301:Alveolar Bone Loss / Q000150:complications* / Q000000981:diagnostic imaging; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D004164:Diphosphonates / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008336:Mandibular Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D010024:Osteoporosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D019252:Radiography, Dental, Digital; D012307:Risk Factors; D014807:Vitamin D / Q000627:therapeutic use
D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D014807:Vitamin D; D002118:Calcium