Supramolecular conjugates of carbon nanotubes and DNA by a solid-state reaction.
DNA-wrapped nanotubes of both multiwalled and single-walled carbon nanotubes were obtained by a solid-state mechanochemical reaction. Scanning electron microscopic images show that the nanotubes were cut into shorter lengths and were fully covered with DNA, which was further confirmed by fluorescence microscopy. This resulted in a high aqueous solubility of the products with a stability of >6 months. The results show that nanotubes were cut also with uniform distribution where >90% of the multiwalled products were 500 nm to 3 microm and 80% of the single-walled products were 250 nm to 1 microm in length, respectively. UV-vis spectra and gel electrophorosis show that the DNA in the product is intact. This facile technique for obtaining supramolecularly masked, water-soluble carbon nanotubes by a solid-state reaction has a great potential for both biological and nonbiological applications of nanotubes.
Nepal
Dhriti
D
Department of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), 500-712 Gwangju, South Korea.
Sohn
Jung-Inn
JI
Aicher
Wilhelm K
WK
Lee
Seonghoon
S
Geckeler
Kurt E
KE
D000941:Antigens; D001672:Biocompatible Materials / Q000737:chemistry*; D001704:Biopolymers / Q000737:chemistry*; D015374:Biosensing Techniques; D002621:Chemistry / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods*; D046911:Macromolecular Substances / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D036103:Nanotechnology / Q000379:methods; D043942:Nanotubes / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D013053:Spectrophotometry; D014466:Ultraviolet Rays
D000941:Antigens; D001672:Biocompatible Materials; D001704:Biopolymers; D046911:Macromolecular Substances; D037742:Nanotubes, Carbon; D004247:DNA