Wireless electrodeless piezomagnetic biosensor with an isolated nickel oscillator.
This study presents a fundamental concept of piezomagnetic biochemical sensor driven in a wireless-electrodeless manner. A stepped cylindrical rod of nickel is used as the oscillator, which traps the vibrational energy of axially-polarized surface-shear waves in the central part, where the diameter is slightly larger. A meander-line coil surrounding the oscillator with an air gap can cause and detect the resonant vibrations of the surface-shear waves via the piezomagnetic effect. The resonant frequency of the trapped-mode resonance is continuously measured to detect human immunoglobulin G (IgG). It decreased by 0.08% when a solution containing IgG was injected into the glass cell where the oscillator was placed alone. This oscillator is useful for fundamental studies of various biochemical reactions in a closed system in different environmental gases and different pressures.
Ogi
Hirotsugu
H
Graduate School of Engineering Science, Osaka University, Machikaneyama 1-3, Toyonaka, Osaka 560-8531, Japan.
Motohisa
Kazuma
K
Matsumoto
Takashi
T
Mizugaki
Tomoo
T
Hirao
Masahiko
M
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D009532:Nickel; D013205:Staphylococcal Protein A / Q000032:analysis
D007074:Immunoglobulin G; D013205:Staphylococcal Protein A; D009532:Nickel