Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus.
Multiprotein bridging factor 1 (MBF1) is a transcriptional coactivator. It has been reported that MBF1 changed its subcellular localization from cytoplasm into nuclei with a transcriptional activator for activation of a target gene expression in animals. We found that Arabidopsis MBF1s (AtMBF1s) predominantly localize in nucleolus. We previously reported that plant MBF1s were rapidly induced by several stresses, whereas animal MBF1s were not induced. Therefore, we suggest that MBF1-function in plants is controlled on the level of transcriptional induction but not by nuclear translocation, dissimilar from the case of MBF1s from animals.
Sugikawa
Yoichi
Y
Laboratory of Environmental Molecular Biology, Graduate School of Environmental Earth Science, Hokkaido University, Kita 10, Nishi 5, Kita-ku, Sapporo 060-0810, Japan.
Ebihara
Satoe
S
Tsuda
Kenichi
K
Niwa
Yasuo
Y
Yamazaki
Ken-Ichi
K
D017360:Arabidopsis / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D002466:Cell Nucleolus / Q000737:chemistry* / Q000378:metabolism; D049452:Green Fluorescent Proteins / Q000032:analysis / Q000235:genetics; D007120:Immunochemistry; D015534:Trans-Activators / Q000032:analysis* / Q000235:genetics / Q000378:metabolism
D029681:Arabidopsis Proteins; C491466:MBF1 protein, Arabidopsis; D015534:Trans-Activators; D049452:Green Fluorescent Proteins