An amino acid contributing to pockets A, B, and D of the peptide-binding groove is altered in A*0315.
Horn
P A
PA
Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
DeLuca
D S
DS
Blasczyk
R
R
D000328:Adult; D000483:Alleles; D001665:Binding Sites; D005260:Female; D014644:Genetic Variation; D015234:HLA-A Antigens / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics* / Q000378:metabolism; D010649:Phenylalanine / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D011485:Protein Binding; D014443:Tyrosine / Q000737:chemistry; D044465:White People
D015234:HLA-A Antigens; D010446:Peptide Fragments; D014443:Tyrosine; D010649:Phenylalanine