Tissue necrosis after intramuscular administration of diclofenac: report of one case.
A seven-year-old girl received intramuscular injection of diclofenac for symptomatic treatment of her fever. Aseptic tissue necrosis occurred around the injection site. Although there was no sequela left after wound care and surgical interventions, unwanted morbidity had resulted. Fever is just a symptom but not a disease itself. We should work more aggressively to evaluate the potential infection rather than treat the fever only. If it is necessary to lower the body temperature, external cooling, oral medication would suffice. Suppository is reserved for children when oral intake is not possible, and injection should be the last resort.
Lai
Mary
M
Department of Emergency Medicine, Chiayi Christian Hospital, Chiayi City, Taiwan.
Huang
Ying-Chieh
YC
Yao
Pi-Chun
PC
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D004008:Diclofenac / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005334:Fever / Q000188:drug therapy; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D009132:Muscles / Q000473:pathology*; D009336:Necrosis / Q000209:etiology; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac