High cholesterol, triglycerides, and body-mass index in suicide attempters.
Low cholesterol concentrations and cholesterol-lowering therapies have been suggested to be associated with increased suicidality. This article examined the association of cholesterol, triglycerides, and body-mass index (BMI) with suicidal ideation and suicide attempts. Findings are based on a nationally representative community sample of n = 4,181 subjects (18-65 years) examined with a standardized diagnostic interview (CIDI) for (DSM-IV) mental disorders. Controlling for age and gender the study revealed a moderate positive association between cholesterol, triglycerides, BMI, and suicide attempts in subjects with depressive symptoms during the past 12 months (n = 1,205). The results of this study are compatible with two recent epidemiological cohort studies showing a positive association between cholesterol and completed suicide.
Brunner
Jürgen
J
Max Planck Institute of Psychiatry, Munich, Germany. jbrunner@mpipsykl.mpg.de
Bronisch
Thomas
T
Pfister
Hildegard
H
Jacobi
Frank
F
Höfler
Michael
M
Wittchen
Hans-Ulrich
HU
D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D003866:Depressive Disorder / Q000097:blood / Q000453:epidemiology*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D012307:Risk Factors; D013406:Suicide, Attempted / Q000706:statistics & numerical data*; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides; D002784:Cholesterol