title: Hydrophobic tyrosyl probes for monitoring nitration reactions in membranes.
abstract: In this chapter, the upregulation of the proteasomal enzymes in response to nitric oxide (NO) in endothelial cells is discussed. The cytoprotective effects of NO are discussed in relation to iron homeostasis, oxidative stress, and the cellular proteasomal function. The role of NO-dependent proteolytic signaling mechanism is important to the overall understanding of the redox signaling in oxidative endothelial cell injury.
authors.affiliation: Department of Biophysics, Free Radical Research Center, Medical College of Wisconsin, Milwaukee, WI 53226-0509, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.forename: Joy
authors.initials: J
authors.lastname: Joseph
authors.forename: B
authors.initials: B
authors.lastname: Kalyanaraman
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D004727:Endothelium / Q000166:cytology / Q000201:enzymology / Q000378:metabolism; D015335:Molecular Probes; D009566:Nitrates / Q000378:metabolism*; D018384:Oxidative Stress; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D014443:Tyrosine / Q000737:chemistry*
chemical_list: D015335:Molecular Probes; D009566:Nitrates; D014443:Tyrosine; D046988:Proteasome Endopeptidase Complex