High rate of resistance to quinupristin-dalfopristin in Enterococcus faecium clinical isolates from Korea.
We tested the in vitro susceptibilities of 603 enterococcal isolates from eight tertiary-care hospitals in Korea. The quinupristin-dalfopristin resistance rate in Enterococcus faecium was very high (25 isolates, 10.0%). It was suggested that both clonal spread and the sporadic emergence of quinupristin-dalfopristin-resistant isolates may explain the high prevalence of quinupristin-dalfopristin resistance in Korea.
Oh
Won Sup
WS
Division of Infectious Diseases, Samsung Medical Center, Seoul, Korea.
Ko
Kwan Soo
KS
Song
Jae-Hoon
JH
Lee
Mi Young
MY
Park
Sulhee
S
Peck
Kyong Ran
KR
Lee
Nam Yong
NY
Kim
Choon-Kwan
CK
Lee
Hyuck
H
Kim
Shin-Woo
SW
Chang
Hyun-Ha
HH
Kim
Yeon-Sook
YS
Jung
Sook-In
SI
Son
Jun Seong
JS
Yeom
Joon-Sup
JS
Ki
Hyun Kyun
HK
Woo
Gun-Jo
GJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple / Q000502:physiology*; D016984:Enterococcus faecium / Q000187:drug effects*; D006801:Humans; D007723:Korea / Q000453:epidemiology; D014769:Virginiamycin / Q000031:analogs & derivatives* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D014769:Virginiamycin; C062940:quinupristin-dalfopristin