title: Effects of conversion from cyclosporine to tacrolimus on left ventricular structure in cardiac allograft recipients.
abstract: Twelve heart transplant recipients selected for conversion from cyclosporine to tacrolimus because of adverse effects of cyclosporine therapy underwent echocardiography at baseline and 6 months after conversion. Left ventricular mass decreased by 24% and left ventricular geometry returned toward normal at 6 months after conversion, without significant changes in blood pressure.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Medical University of South Carolina, Gazes Cardiac Research Institute, Charleston 29425, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Peura
authors.forename: Michael R
authors.initials: MR
authors.lastname: Zile
authors.forename: David S
authors.initials: DS
authors.lastname: Feldman
authors.forename: Adrian B
authors.initials: AB
authors.lastname: VanBakel
authors.forename: Catherine
authors.initials: C
authors.lastname: McClure
authors.forename: Walter
authors.initials: W
authors.lastname: Uber
authors.forename: Hwajoo
authors.initials: H
authors.lastname: Haynes
authors.forename: Naveen L
authors.initials: NL
authors.lastname: Pereira
mesh_terms: D016572:Cyclosporine / Q000494:pharmacology*; D005260:Female; D016027:Heart Transplantation; D006352:Heart Ventricles / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016559:Tacrolimus / Q000494:pharmacology*; D014184:Transplantation, Homologous; D020257:Ventricular Remodeling / Q000187:drug effects*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D016559:Tacrolimus