title: Horizontal transfer of erythromycin resistance from Clostridium difficile to Butyrivibrio fibrisolvens.
abstract: This study demonstrates for the first time the in vitro transfer of the erythromycin resistance gene erm(B) between two obligate anaerobes, the human spore-forming pathogen Clostridium difficile and the rumen commensal Butyrivibrio fibrisolvens, suggesting that this event might occur also in the natural environment.
authors.affiliation: Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Spigaglia
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Barbanti
authors.forename: Paola
authors.initials: P
authors.lastname: Mastrantonio
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D045856:Butyrivibrio / Q000187:drug effects / Q000235:genetics*; D002417:Cattle; D016360:Clostridioides difficile / Q000187:drug effects / Q000235:genetics*; D004351:Drug Resistance / Q000235:genetics*; D022761:Gene Transfer, Horizontal; D008780:Methyltransferases / Q000235:genetics*; D008969:Molecular Sequence Data; D012417:Rumen / Q000382:microbiology
chemical_list: D001426:Bacterial Proteins; C111078:ErmTR protein, bacteria; D008780:Methyltransferases