title: Ruthenium-catalyzed cycloaddition of alkynes and organic azides.
abstract: Cp*RuCl(PPh3)2 is an effective catalyst for the regioselective "fusion" of organic azides and terminal alkynes, producing 1,5-disubstituted 1,2,3-triazoles. Internal alkynes also participate in this catalysis, resulting in fully substituted 1,2,3-triazoles.
authors.affiliation: Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Xinguo
authors.initials: X
authors.lastname: Chen
authors.forename: Peng
authors.initials: P
authors.lastname: Xue
authors.forename: Herman H Y
authors.initials: HH
authors.lastname: Sun
authors.forename: Ian D
authors.initials: ID
authors.lastname: Williams
authors.forename: K Barry
authors.initials: KB
authors.lastname: Sharpless
authors.forename: Valery V
authors.initials: VV
authors.lastname: Fokin
authors.forename: Guochen
authors.initials: G
authors.lastname: Jia
mesh_terms: D000114:Acetylene / Q000031:analogs & derivatives / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; C044736:phenylacetylene; D012428:Ruthenium; D000114:Acetylene