A second case of -1 ribosomal frameshifting affecting a major virion protein of the Lactobacillus bacteriophage A2.
The bacteriophage A2 major tail protein gene utilizes a -1 translational frameshift to generate two structural polypeptides. Frameshifting is promoted by a slippery sequence and an RNA pseudoknot located 3' of the gene. The major head gene presents a similar recoding ability. A2 is the only phage described with two -1 frameshifts.
Rodríguez
Isabel
I
Area de Microbiología, Facultad de Medicina, Universidad de Oviedo, Spain.
García
Pilar
P
Suárez
Juan E
JE
D000595:Amino Acid Sequence; D001435:Bacteriophages / Q000235:genetics*; D001483:Base Sequence; D018965:Frameshifting, Ribosomal; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D007778:Lactobacillus / Q000235:genetics / Q000821:virology*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D016415:Sequence Alignment; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D014771:Virion / Q000235:genetics*
D014764:Viral Proteins