Immunoglobulin G kappa [IgG kappa] and IgG lambda paraproteinemia in a child with AIDS and response to highly active antiretroviral therapy.
We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(kappa)] and IgG lambda [IgG(lambda)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of controlling B-cell activation.
Seeborg
Filiz Odabasi
FO
Section of Allergy & Immunology, Texas Children's Hospital and Baylor College of Medicine, 6621 Fannin Street (MC; FC330.01), Houston, Texas 77030, USA. fodabasi@hotmail.com
Gay
Hannah
H
Schmiege
Lorenz M
LM
Bernard
David
D
Shearer
William T
WT
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000188:drug therapy* / Q000276:immunology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D007146:Immunoglobulin lambda-Chains / Q000097:blood*; D008297:Male; D010265:Paraproteinemias / Q000276:immunology*
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains