title: Perthes' disease in the very young child.
abstract: We report two cases of very young children who presented with irritable hips and in whom magnetic resonance imaging with gadolinium-enhancement revealed ischaemic changes affecting the capital ossific nucleus. Radiological changes consistent with Perthes' disease subsequently appeared. In the published literature Perthes' disease has been reported in children as young as 24 months. Gadolinium-enhanced magnetic resonance imaging has revealed Perthes' disease in younger children which can predate the appearance of radiographic changes by up to 3 months.
authors.affiliation: Department of Orthopaedics, Southampton General Hospital, Southampton, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Gent
authors.forename: Prasad
authors.initials: P
authors.lastname: Antapur
authors.forename: Joanne
authors.initials: J
authors.lastname: Fairhurst
authors.forename: Graeme R
authors.initials: GR
authors.lastname: Taylor
authors.forename: Nicholas M P
authors.initials: NM
authors.lastname: Clarke
mesh_terms: D003287:Contrast Media; D005270:Femur Head / Q000473:pathology; D019786:Gadolinium DTPA; D006801:Humans; D007223:Infant; D007873:Legg-Calve-Perthes Disease / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012598:Sclerosis / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA