title: Identification of serovar-specific single-nucleotide polymorphisms of C. Trachomatis omp1 gene.
abstract: Complete sequences of omp1 gene encoding chlamydial main outer membrane protein were analyzed in 76 clinical strains of C. trachomatis. Thirty-four serovar-specific single-nucleotide polymorphisms were identified, 20 of them meet two criteria: unique position of the nucleotide and unique nucleotide substitution. Evaluation of serovar-specific single-nucleotide polymorphisms of omp1 gene can appreciably simplify and accelerate genetic diagnosis of C. trachomatis serovars.
authors.affiliation: Institute of Physicochemical Medicine, Ministry of Health of Russian Federation, Moscow.
authors.forename: V I
authors.initials: VI
authors.lastname: Sharkeev
authors.forename: I Y
authors.initials: IY
authors.lastname: Torshin
authors.forename: M M
authors.initials: MM
authors.lastname: Shkarupeta
authors.forename: T A
authors.initials: TA
authors.lastname: Akopian
authors.forename: V N
authors.initials: VN
authors.lastname: Lazarev
authors.forename: V M
authors.initials: VM
authors.lastname: Govorun
mesh_terms: D002692:Chlamydia trachomatis / Q000235:genetics*; D014644:Genetic Variation; D008957:Models, Genetic; D020641:Polymorphism, Single Nucleotide; D018272:Porins / Q000235:genetics*; D017422:Sequence Analysis, DNA; D013045:Species Specificity
chemical_list: D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis