title: Ir-catalysed asymmetric hydrogenation: Ligands, substrates and mechanism.
abstract: Relatively air and moisture tolerant cationic iridium complexes, with chiral non-racemic N,P-ligands and weakly coordinating counter ions, are efficient catalysts in the asymmetric hydrogenation of olefins. Unfunctionalised olefins are particularly difficult substrates because, in general, a polar group adjacent to the alkene bond is required for high catalytic activity and enantioselectivity. The applicability towards a variety of substrates and choice of ligands reported thus far in the literature, as well as the mechanism, selectivity issues and the importance of the anion are also discussed.
authors.affiliation: Uppsala Universitet, Avd. f. Organisk Kemi, Kemiska Institutionen, Box 559, 751 24 Uppsala, Sweden.
authors.forename: Klas
authors.initials: K
authors.lastname: Källström
authors.forename: Ian
authors.initials: I
authors.lastname: Munslow
authors.forename: Pher G
authors.initials: PG
authors.lastname: Andersson