Synthesis of 1-alkyl-4-imidazolecarboxylates: a catch and release strategy.
The novel alkyl N-methyl-N-polystyreneamino-2-isocyanoacrylate was used for the synthesis of 1-substituted imidazole-4-carboxylates utilizing a "catch and release" methodology. The reactions were performed under microwave irradiation, affording the title compounds in both high yields and chemical purity directly to solution, from the solid phase support.
De Luca
Lidia
L
Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy.
Giacomelli
Giampaolo
G
Porcheddu
Andrea
A