title: Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction.
abstract: Asymmetric intramolecular Michael reaction catalyzed by an organocatalyst derived from cysteine has been developed for the synthesis of chiral bicyclo[4.3.0]nonene and cis-disubstituted cyclopentane skeletons with a creation of three or two contiguous chiral centers in good yield with high diastereo- and excellent enantioselectivities.
authors.affiliation: Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. hyashi@ci.kagu.tus.ac.jp
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Gotoh
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Tamura
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: Ryouhei
authors.initials: R
authors.lastname: Masui
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Shoji
mesh_terms: D002384:Catalysis; D003545:Cysteine / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003545:Cysteine