title: Polychlorinated biphenyls in serum of the Siberian Yupik people from St. Lawrence Island, Alaska.
abstract: OBJECTIVE
  To determine serum levels of polychlorinated biphenyls (PCBs) in Siberian Yupik adults from St. Lawrence Island, Alaska, and to determine the relative contribution of atmospheric transport of PCBs and local contamination to body burdens.
  
  
  METHODS
  Siberian Yupiks of various ages were recruited from three populations: residents of the village of Gambell, residents of the village of Savoonga who did not have family hunting camps near the Northeast Cape (NEC), a Formerly Used Defense Site (FUDS) known to be contaminated with PCBs, and residents of Savoonga whose families had a hunting camp at the NEC.
  
  
  METHODS
  Levels of PCBs were measured in serum samples from 130 people, ages 19-76. These Alaska Natives follow a traditional diet high in marine mammals and fish, which bioconcentrate organochlorine compounds that migrate to the Arctic via global air transport and ocean currents.
  
  
  RESULTS
  The lipid-adjusted serum PCB levels of those members of families with hunting camps at the NEC had a mean lipid-adjusted PCB concentration of 1,143 ppb, whereas other residents of Savoonga had values of 847 ppb and residents of Gambell had values of 785 ppb.
  
  
  CONCLUSIONS
  Our observations suggest that atmospheric transport of PCBs contributes to levels in the Yupik people, but that the abandoned military site at the NEC may also contribute to the human body burden in those individuals who have either spent substantial time or consumed food from there.
authors.affiliation: Institute for Health and the Environment, University at Albany, Rensselaer, New York 12144, USA. Carpent@uamail.albany.edu
authors.forename: David O
authors.initials: DO
authors.lastname: Carpenter
authors.forename: Anthony P
authors.initials: AP
authors.lastname: DeCaprio
authors.forename: David
authors.initials: D
authors.lastname: O'Hehir
authors.forename: Farooq
authors.initials: F
authors.lastname: Akhtar
authors.forename: Glenn
authors.initials: G
authors.lastname: Johnson
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Scrudato
authors.forename: Lucy
authors.initials: L
authors.lastname: Apatiki
authors.forename: Jane
authors.initials: J
authors.lastname: Kava
authors.forename: Jesse
authors.initials: J
authors.lastname: Gologergen
authors.forename: Pamela K
authors.initials: PK
authors.lastname: Miller
authors.forename: Lorraine
authors.initials: L
authors.lastname: Eckstein
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000413:Alaska / Q000453:epidemiology; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D004930:Inuit / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011078:Polychlorinated Biphenyls / Q000097:blood*; D017678:Sex Distribution
chemical_list: D011078:Polychlorinated Biphenyls