title: Polyhedral oligomeric silsesquioxane nanocomposites: the next generation material for biomedical applications.
abstract: The unique properties of nanocomposites have seen them creating the next revolution in materials science. Their quantal properties as a result of their size have given them unique physical characteristics, previously not possible because of classical physical laws. There is now evidence that these may also extend into the world of biology and medicine. In this Account, we look at the birth of a new generation of silica nanocomposites using polyhedral oligomeric silsesquioxanes, a promising nanoscale silica particle with particular use in cardiovascular interventional devices.
authors.affiliation: Biomaterials & Tissue Engineering Centre (BTEC), University College London, London, United Kingdom.
authors.forename: Ruben Y
authors.initials: RY
authors.lastname: Kannan
authors.forename: Henryk J
authors.initials: HJ
authors.lastname: Salacinski
authors.forename: Peter E
authors.initials: PE
authors.lastname: Butler
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Seifalian
mesh_terms: D035843:Biomedical Research; D036103:Nanotechnology; D017646:Organosilicon Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D017646:Organosilicon Compounds; D011108:Polymers