[Cholesterol emboli during coumarin therapy].
A 71-year-old patient suddenly developed a painful, bizarre livid erythema on the right foot. Based upon the clinical and histological presentation, cholesterol emboli were diagnosed. These cholesterol emboli were induced by therapy with phenprocoumon (a coumarin derivative), which had been initiated 5 months previously. Arterial emboli may rarely occur during anticoagulation and have to be included in the differential diagnosis.
Lüftl
Matthias
M
Dermatologische Universitätsklinik Erlangen. matthias.lueftl@derma.imed.uni-erlangen.de
Schuler
Gerold
G
Simon
Miklós
M
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D003374:Coumarins / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D017700:Embolism, Cholesterol / Q000139:chemically induced* / Q000175:diagnosis*; D004890:Erythema / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D005533:Foot Dermatoses / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans
D000925:Anticoagulants; D003374:Coumarins; C030123:coumarin