Heat shock protein 90 inhibitors. A text book example of medicinal chemistry?
Janin
Yves L
YL
URA 2128 CNRS-Institut Pasteur, 28 Rue du Dr. Roux, 75724 Paris Cedex 15, France. yljanin@pasteur.fr
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry*; D016227:Benzoquinones; D015195:Drug Design; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors*; D006801:Humans; D047029:Lactams, Macrocyclic; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry; D018942:Macrolides; D011809:Quinones / Q000138:chemical synthesis / Q000737:chemistry; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D016227:Benzoquinones; D018841:HSP90 Heat-Shock Proteins; D047029:Lactams, Macrocyclic; D007783:Lactones; D018942:Macrolides; D011809:Quinones; C035359:monorden; C001277:geldanamycin