cDNA microarray-based translational research in soft tissue sarcoma.
The authors discuss application of cDNA microarray technology in translational research to identify diagnostic markers and therapeutic targets in adult soft tissue sarcoma. Recent results in synovial sarcoma are used to highlight the applicability of this technology for marker and target discovery, as well as the need for preclinical validation of putative therapeutic targets.
Lubieniecka
Joanna M
JM
Nielsen
Torsten O
TO
D000328:Adult; D046152:Gastrointestinal Stromal Tumors / Q000235:genetics; D020869:Gene Expression Profiling; D006801:Humans; D025202:Molecular Diagnostic Techniques; D020411:Oligonucleotide Array Sequence Analysis; D012509:Sarcoma / Q000175:diagnosis / Q000235:genetics*; D013584:Sarcoma, Synovial / Q000175:diagnosis / Q000235:genetics; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000235:genetics*