title: Simultaneous vs. sequential laparoscopic bilateral native nephrectomy and renal transplantation.
abstract: We reviewed our experience with simultaneous single incision bilateral native nephrectomy and renal transplantation in 11 patients (Group 1), compared to seven recipients who underwent staged laparoscopic bilateral nephrectomy followed by kidney transplantation (Group 2). Mean age, donor source, sex, cause of ESRD, and specimen size were similar in both groups (P=0.1). All Group 2 patients and 9 of 11 Group 1 patients had autosomal-dominant polycystic kidney disease. Perioperative Group 1 complications included: bowel injury, transplant urine leak, necrotic pancreatitis, delayed bowel movement, and severe shoulder pain secondary to diaphragmatic irritation. Seven (63.6%) Group 1 patients required an additional surgical procedure: midline incisional hernia, repair ureteral fistula, and repair enterocutaneous fistula. One Group 1 patient lost his graft secondary to bowel injury and intra-abdominal sepsis. No major complications, reoperations, or graft loss occurred in Group 2. For simultaneous bilateral native nephrectomy and kidney transplantation, over 60% of patients required an additional surgical procedure. Laparoscopic bilateral nephrectomy followed by kidney transplantation is a safe and feasible alternative.
authors.affiliation: Section of Renal Transplantation, Laparoscopic, and Minimally Invasive Surgery, Glickman Urological Institute/Transplant Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
authors.forename: Hazem R
authors.initials: HR
authors.lastname: Ismail
authors.forename: Stuart M
authors.initials: SM
authors.lastname: Flechner
authors.forename: Jihad H
authors.initials: JH
authors.lastname: Kaouk
authors.forename: Ithaar H
authors.initials: IH
authors.lastname: Derweesh
authors.forename: Inderbir S
authors.initials: IS
authors.lastname: Gill
authors.forename: Charles
authors.initials: C
authors.lastname: Modlin
authors.forename: David
authors.initials: D
authors.lastname: Goldfarb
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Novick
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D016030:Kidney Transplantation; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011183:Postoperative Complications