Synthesis of conformationally constrained C-glycosyl alpha- and beta-amino acids and sugar-carbamino sugar hybrids via Diels-Alder reaction.
[structure: see text] Sugar-derived dienes undergo Diels-Alder reactions with methyl alpha-nitro acrylate and ethyl beta-nitro acrylate to form the corresponding cycloadducts which have been converted into conformationally constrained C-glycosyl alpha- and beta-amino acids. Further, these beta-amino acids are converted into sugar-carbamino sugar hybrid molecules.
Jayakanthan
K
K
Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India.
Vankar
Yashwant D
YD
D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002241:Carbohydrates / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism
D000596:Amino Acids; D002241:Carbohydrates