title: [Comparison of the bispectral index and spectral entropy in gynecological surgery].
abstract: OBJECTIVE
  Spectral entropy quantifies variations in cortical electrical activity measured by electroencephalography and frontal activity measured by electromyography. The aim of this study, in the context of general anesthesia, was to compare bispectral index values with the two components of spectral entropy: state entropy and response entropy.
  
  
  METHODS
  Sixteen women (ASA I-II) undergoing gynecological surgery were enrolled. The bispectral index was maintained between 40 and 50 for all patients. Both sensors, for monitoring the bispectral index and spectral entropy, were placed on each patient. Simultaneous readings were recorded at the following moments: operating room arrival, induction, relaxation, intubation, switching on the vaporizer, start of surgery, traction of the intestinal mesenteries and maneuvering of the electric scalpel, switching off the vaporizer, end of surgery, during cough, extubation, and eye opening. The data sets were subjected to analysis of variance, and the intraclass correlation coefficient (ICC) was used to analyze agreement.
  
  
  RESULTS
  Differences between mean values of the bispectral index, state entropy and response entropy were observed at operating room arrival, intubation, and induction. Differences when the patient awakened from anesthesia were observed only between the bispectral index and response entropy, on the one hand, and state entropy on the other. There was no agreement (ICC<0.7) upon operating room arrival, maneuvering the electric scalpel, or awakening from anesthesia.
  
  
  CONCLUSIONS
  The bispectral index, state entropy, and response entropy show good agreement during recordings that reflect the effects of anesthesia. The differences observed at baseline and upon awakening can be attributed to frontal electromyographic activity. Distinguishing cortical electrical activity from frontal electromyographic activity may provide additional information in these situations.
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona. clara.espi@uv.es
authors.forename: C
authors.initials: C
authors.lastname: Espí
authors.forename: P
authors.initials: P
authors.lastname: Vila
authors.forename: S
authors.initials: S
authors.lastname: Muñoz
authors.forename: M
authors.initials: M
authors.lastname: Monerris
authors.forename: V
authors.initials: V
authors.lastname: Mazo
authors.forename: J
authors.initials: J
authors.lastname: Canet
mesh_terms: D000768:Anesthesia, General; D002540:Cerebral Cortex / Q000502:physiology; D003243:Consciousness; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods*; D004576:Electromyography / Q000295:instrumentation / Q000379:methods*; D005152:Facial Muscles / Q000502:physiology; D005260:Female; D005546:Forehead; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007044:Hysterectomy; D007813:Laparotomy; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000295:instrumentation / Q000379:methods*; D009119:Muscle Contraction; D009862:Online Systems; D013057:Spectrum Analysis; D014474:Unconsciousness; D014851:Wakefulness