title: High cholesterol, triglycerides, and body-mass index in suicide attempters.
abstract: Low cholesterol concentrations and cholesterol-lowering therapies have been suggested to be associated with increased suicidality. This article examined the association of cholesterol, triglycerides, and body-mass index (BMI) with suicidal ideation and suicide attempts. Findings are based on a nationally representative community sample of n = 4,181 subjects (18-65 years) examined with a standardized diagnostic interview (CIDI) for (DSM-IV) mental disorders. Controlling for age and gender the study revealed a moderate positive association between cholesterol, triglycerides, BMI, and suicide attempts in subjects with depressive symptoms during the past 12 months (n = 1,205). The results of this study are compatible with two recent epidemiological cohort studies showing a positive association between cholesterol and completed suicide.
authors.affiliation: Max Planck Institute of Psychiatry, Munich, Germany. jbrunner@mpipsykl.mpg.de
authors.forename: Jürgen
authors.initials: J
authors.lastname: Brunner
authors.forename: Thomas
authors.initials: T
authors.lastname: Bronisch
authors.forename: Hildegard
authors.initials: H
authors.lastname: Pfister
authors.forename: Frank
authors.initials: F
authors.lastname: Jacobi
authors.forename: Michael
authors.initials: M
authors.lastname: Höfler
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Wittchen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D003866:Depressive Disorder / Q000097:blood / Q000453:epidemiology*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D012307:Risk Factors; D013406:Suicide, Attempted / Q000706:statistics & numerical data*; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides; D002784:Cholesterol