title: [Less mutilating treatment of penile carcinoma].
abstract: Four patients with penile carcinoma are described. A 60-year-old man with a T1-tumour underwent penis-conserving laser treatment. Two men, aged 52 and 65 years old, with T2-tumors and clinically node-negative groins underwent penile amputation. Sentinel-node biopsy (SNB) revealed no metastases in the 52-year-old patient. High-resolution ultrasound-guided fine-needle aspiration cytology revealed bilateral metastases in the other patient, who underwent bilateral inguinal lymphadenectomy. In the fourth patient, a 73-year-old man with a T3-tumor, a pathological lymph node was palpated in one groin. Inguinal lymphadenectomy revealed 3 positive nodes and an additional pelvic lymphadenectomy was performed. SNB on the other side was positive and inguinal lymphadenectomy followed. No additional positive nodes were found in the dissection specimen. All patients were alive without evidence of disease 4, 3, 3 and 4 years later, respectively. New developments in the management of penile cancer such as laser treatment, high-resolution ultrasonography and SNB result in a more tailored approach with less morbidity without reducing survival rates.
authors.affiliation: Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis, afd. Urologie, Plesmanlaan 121, 1066 CX Amsterdam.
authors.forename: B K
authors.initials: BK
authors.lastname: Kroon
authors.forename: S
authors.initials: S
authors.lastname: Horenblas
authors.forename: O E
authors.initials: OE
authors.lastname: Nieweg
mesh_terms: D000368:Aged; D000671:Amputation, Surgical; D001707:Biopsy, Needle; D018572:Disease-Free Survival; D006801:Humans; D007264:Inguinal Canal; D053685:Laser Therapy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D021701:Sentinel Lymph Node Biopsy; D016896:Treatment Outcome; D014463:Ultrasonography