title: Intramolecular alkyne hydroalkoxylation and hydroamination catalyzed by iridium hydrides.
abstract: [reaction: see text] Iridium(III) hydrides prove to be air-stable active catalysts for intramolecular hydroalkoxylation and hydroamination of internal alkynes with proximate nucleophiles. The cyclization follows highly selective 6-endo-dig regiochemistry when regioselectivity is an issue.
authors.affiliation: Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520-8107, USA.
authors.forename: Xingwei
authors.initials: X
authors.lastname: Li
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Chianese
authors.forename: Tiffany
authors.initials: T
authors.lastname: Vogel
authors.forename: Robert H
authors.initials: RH
authors.lastname: Crabtree