title: QTL mapping for teat number in an Iberian-by-Meishan pig intercross.
abstract: The aim of this study was to investigate chromosomal regions affecting the number of teats in pigs and possible epistatic interactions between the identified quantitative trait loci (QTL). An experimental F2 cross between Iberian and Chinese Meishan lines was used for this purpose. A genomic scan was conducted with 117 markers covering the 18 porcine autosomes. Linkage analyses were performed by interval mapping using an animal model to estimate QTL and additive polygenic effects. Complementary analyses with models fitting two QTL were also carried out. The results showed three genomewide significant QTL mapping on chromosomes 5, 10 and 12, whose joint action control up to 30% of the phenotypic variance of the trait. Meishan alleles had a positive additive effect on teat number, and a positive-additive x additive-epistatic interaction was detected between QTL on chromosomes 10 and 12.
authors.affiliation: Departamento de Mejora Genética Animal, SGIT-INIA, Madrid 28040, Spain. valdo@inia.es
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Tomás
authors.forename: E
authors.initials: E
authors.lastname: Alves
authors.forename: O
authors.initials: O
authors.lastname: Ramirez
authors.forename: M
authors.initials: M
authors.lastname: Arqué
authors.forename: G
authors.initials: G
authors.lastname: Muñoz
authors.forename: C
authors.initials: C
authors.lastname: Barragán
authors.forename: L
authors.initials: L
authors.lastname: Varona
authors.forename: L
authors.initials: L
authors.lastname: Silió
authors.forename: M
authors.initials: M
authors.lastname: Amills
authors.forename: J L
authors.initials: JL
authors.lastname: Noguera
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004843:Epistasis, Genetic; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D005838:Genotype; D016013:Likelihood Functions; D008321:Mammary Glands, Animal / Q000033:anatomy & histology*; D040641:Quantitative Trait Loci; D034421:Sus scrofa / Q000235:genetics*
chemical_list: D005819:Genetic Markers