In vitro activity of zinc oxide-eugenol and glass ionomer cements on Candida albicans.
The aim of this study was to evaluate in vitro the antimicrobial activity of glass ionomer (GIC) and zinc oxide-eugenol (ZOE) cements against Candida albicans. Standardized GIC and ZOE specimens were maintained in contact with C. albicans suspension (1 x 10(6) cells/ml) at 37 degrees C for 24 h, 48 h or 7 days. A control group without any testing cement was included. After the incubation period, aliquots of 0.1 ml were plated on Sabouraud's agar, and then the number of colonies was counted. The results were expressed as values of logarithms of colony-forming units per milliliter (log CFU/mL) and were analyzed statistically by Kruskal-Wallis ANOVA. After 48 h of incubation, the ZOE group presented no growth of C. albicans. GIC and control groups presented similar mean values at all tested periods. According to the results obtained, it could be concluded that, under the experimental conditions, ZOE cement was more effective in vitro against C. albicans than GIC.
Cassanho
Anna Carolina Aguiar
AC
School of Dentistry of São José dos Campos, São Paulo State University.
Fernandes
Aletéia Massula
AM
Oliveira
Luciane Dias de
LD
Carvalho
Claudio Antonio Talge
CA
Jorge
Antonio Olavo Cardoso
AO
Koga-Ito
Cristiane Yumi
CY
D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D000935:Antifungal Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects*; D002180:Candidiasis, Oral / Q000517:prevention & control; D003786:Dental Pulp Cavity / Q000382:microbiology*; D005899:Glass Ionomer Cements / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D018709:Statistics, Nonparametric; D015035:Zinc Oxide-Eugenol Cement / Q000494:pharmacology*
D000891:Anti-Infective Agents, Local; D000935:Antifungal Agents; D005899:Glass Ionomer Cements; D015035:Zinc Oxide-Eugenol Cement