Tissue typing for hematopoietic cell transplantation: newer techniques and newer antigens for which cross-matching is helpful.
Refinements in human leukocyte antigen (HLA) typing techniques for hematopoietic cell transplantation (HCT) have permitted a more precise assessment of donor-recipient histocompatibility, which has impacted transplantation outcomes. More recently, differences in transplant outcomes associated with killer immunoglobulin-like receptor compatibility have emphasized the potential importance of natural killer (NK) cell typing in HCT. This article reviews the current state of the art for HCT donor selection based on both HLA and NK cell typing.
Iannone
Robert
R
Children's Hospital of Philadelphia and University of Pennsyvania, Philadelphia, PA, USA.
Davies
Stella M
SM
D001788:Blood Grouping and Crossmatching / Q000379:methods*; D002648:Child; D006680:HLA Antigens / Q000276:immunology*; D018380:Hematopoietic Stem Cell Transplantation; D006648:Histocompatibility / Q000276:immunology; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D014181:Transplantation Immunology
D006680:HLA Antigens