title: Robert Koch: the grandfather of cloning?
abstract: This year marks the centenary of Robert Koch's Nobel Prize for discovering the cause of tuberculosis. Koch was also the first scientist to isolate the anthrax and cholera microbes. Yet perhaps one of his greatest contributions to biology is the least appreciated: his method for propagating individual colonies of bacteria on plates, a technique that came to be called cloning.
authors.affiliation: Wohl Virion Centre, Division of Infection and Immunity, University College London, London W1T 4JF, United Kingdom.
authors.forename: Robin A
authors.initials: RA
authors.lastname: Weiss
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000266:history; D001419:Bacteria / Q000302:isolation & purification*; D001432:Bacteriology / Q000266:history*; D018929:Cell Culture Techniques / Q000266:history; D002460:Cell Line; D002999:Clone Cells; D003001:Cloning, Molecular; D019976:Cloning, Organism / Q000266:history; D015169:Colony Count, Microbial / Q000266:history; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008828:Microbiological Techniques / Q000266:history; D009613:Nobel Prize
chemical_list: D000911:Antibodies, Monoclonal