title: P1 latency as a biomarker for central auditory development in children with hearing impairment.
abstract: We used the latency of the P1 cortical auditory-evoked potential (CAEP) as a biomarker for the development of central auditory pathways in three children who received intervention through hearing aids and/or cochlear implants. Our goal was to examine the clinical feasibility of using the latency of the P1 CAEP as an objective tool to evaluate whether acoustic amplification for hearing-impaired children has provided sufficient stimulation for normal development of central auditory pathways. If clinicians have such a marker, then they can more confidently make a decision about whether to provide a child with a cochlear implant following an appropriate hearing-aid trial. Using the same marker, clinicians will also be able to monitor the maturation of central auditory pathways once electrical stimulation is initiated.
authors.affiliation: Behavioral and Brian Sciences, Callier Advanced Hearing Research Center, University of Texas at Dallas 75235, USA. anu.sharma@utdallas.edu
authors.forename: Anu
authors.initials: A
authors.lastname: Sharma
authors.forename: Kathryn
authors.initials: K
authors.lastname: Martin
authors.forename: Peter
authors.initials: P
authors.lastname: Roland
authors.forename: Paul
authors.initials: P
authors.lastname: Bauer
authors.forename: Melissa H
authors.initials: MH
authors.lastname: Sweeney
authors.forename: Phillip
authors.initials: P
authors.lastname: Gilley
authors.forename: Michael
authors.initials: M
authors.lastname: Dorman
mesh_terms: D001306:Auditory Pathways / Q000254:growth & development*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006310:Hearing Aids; D034381:Hearing Loss / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D011930:Reaction Time / Q000502:physiology*