[Influence of x-ray irradiation on phosphorus metabolism in rabbits].
Twenty four rabbits were used in the experiment. The animals were divided into four groups, 6 animals in each. The rabbits were irradiated with a total dose of 910 R. The activity of alkaline phosphatase and the level of inorganic phosphorus were measured on the 5th, 10th and 15th day after irradiation in erythrocytes, plasma, duodenum, muscles and liver. There was found a decrease of phosphatase activity in the plasma, liver and duodenum, and an increase in the muscles and erythrocytes. The level of inorganic phosphorus increased in the duodenum, liver and plasma, and decreased in the muscles and erythrocytes. In the latter two, the increase of the phosphatase activity was accompanied by a decrease of the phosphorus level; on the contrary, the decrease of the enzyme activity in the liver and duodenum was accompanied by an increase of the phosphorus level. During the whole experimental period, the phosphatase activity was higher by about 40% than in the control group.
Ryńca
J
J
Instytut Fizjologii Zwierzat Wydziału Weterynaryjnego, Akademii Rolniczej w Warszawie.
Jakutowicz
K
K
D000244:Adenosine Diphosphate / Q000378:metabolism / Q000528:radiation effects; D000255:Adenosine Triphosphate / Q000378:metabolism / Q000528:radiation effects; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism* / Q000528:radiation effects*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004386:Duodenum / Q000378:metabolism / Q000528:radiation effects; D004912:Erythrocytes / Q000378:metabolism / Q000528:radiation effects; D006321:Heart / Q000528:radiation effects; D007668:Kidney / Q000378:metabolism / Q000528:radiation effects; D008099:Liver / Q000378:metabolism / Q000528:radiation effects; D018482:Muscle, Skeletal / Q000378:metabolism / Q000528:radiation effects; D009206:Myocardium / Q000378:metabolism; D010760:Phosphorus Metabolism Disorders / Q000000981:diagnostic imaging / Q000662:veterinary; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D011877:Radionuclide Imaging; D013997:Time Factors
D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D000469:Alkaline Phosphatase