title: In vitro and in vivo observations on the erythrocyte uptake of 17-monochloroacetylajmaline.
abstract: The in vitro and in vivo observations on the uptake rate of 17-monochloroacetylajmaline by human erythrocytes showed that about 30-35% of the drug is bound to red blood cells. These findings suggest a peculiar affinity of the drug for the erythrocytes, may be for the membrane or stromal phospholipids.
authors.affiliation: General Hospital, Medical Division, Saronno.
authors.forename: M
authors.initials: M
authors.lastname: Lampertico
authors.forename: S B
authors.initials: SB
authors.lastname: Curri
authors.forename: E
authors.initials: E
authors.lastname: Bombardelli
authors.forename: G
authors.initials: G
authors.lastname: Forni
authors.forename: E M
authors.initials: EM
authors.lastname: Martinelli
authors.forename: V
authors.initials: V
authors.lastname: Cucurullo
mesh_terms: D000293:Adolescent; D000328:Adult; D000404:Ajmaline / Q000031:analogs & derivatives* / Q000097:blood; D002855:Chromatography, Thin Layer; D004912:Erythrocytes / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008875:Middle Aged
chemical_list: D000404:Ajmaline; C008541:17-monochloroacetylajmaline