[Facial foreign body granulomas after dermal injection of a polylactate-based implant for wrinkles].
New methods are constantly introduced for soft tissue augmentation to correction of scars and wrinkles. Each method has its advantages and disadvantages. A 48 year old woman developed visible and palpable plaques and papules after treatment of the nasolabial and glabella folds with a poly L-lactic acid implant. Histological examination revealed a foreign body granuloma, while electron microscopy showed remnants of the implant material, demonstrating that poly L-lactic acid can also induce a foreign body reaction.
Oppel
Tilmann
T
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig-Maximilians-Universität München.
Schaller
Martin
M
Flaig
Michael
M
Korting
Hans Christina
HC
D005148:Facial Dermatoses / Q000209:etiology* / Q000473:pathology*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D019344:Lactic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D011091:Polyesters; D011108:Polymers / Q000009:adverse effects* / Q000627:therapeutic use; D019736:Prostheses and Implants / Q000009:adverse effects*; D015361:Rhytidoplasty / Q000009:adverse effects; D015595:Skin Aging / Q000187:drug effects / Q000473:pathology*
D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)