Antimicrobial resistance of Escherichia coli O157 from cattle in Korea.
Of 45 Escherichia coli O157 isolates from cattle feces, which were collected between May 2000 and September 2003 in Korea, 32 were resistant to at least 1 antibiotic and 28 were resistant to 4 or more antibiotics, with 32, 30 and 30 of the isolates being resistant to streptomycin, tetracycline and sulfisoxazole, respectively. Two isolates were resistant to fluoroquinolones and to 10 or more of the 22 other antimicrobial agents that were tested. Thirteen antimicrobial resistant patterns were observed. The most frequent resistance type, which was found for 11 isolates, was streptomycin-tetracycline-kanamycin-ampicillin-piperacillin-cephalothin-sulfisoxazole-ticarcillin. Polymerase chain reaction (PCR) analysis of the isolates for E. coli O157 virulence markers revealed that 25 of the resistant E. coli O157 isolates tested positive for stx2 or both stx1 and stx2 genes. These findings suggest that many of the resistant E. coli O157 isolates might cause disease in humans.
You
Ju-Yeon
JY
Veterinary Public Health, College of Veterinary Medicine, Chonbuk National University, Chonju, 561-756, Republic of Korea.
Moon
Bo-Mi
BM
Oh
In-Gyeong
IG
Baek
Byeong-Kirl
BK
Li
Li-Guang
LG
Kim
Byeong-Su
BS
Stein
Barry D
BD
Lee
John Hwa
JH
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology; D015169:Colony Count, Microbial; D003257:Consumer Product Safety; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary; D019453:Escherichia coli O157 / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D029968:Escherichia coli Proteins / Q000032:analysis*; D005243:Feces / Q000382:microbiology; D005516:Food Microbiology; D006801:Humans; D008460:Meat / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction / Q000379:methods / Q000662:veterinary; D022603:Shiga Toxins / Q000032:analysis / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; D022603:Shiga Toxins; D037521:Virulence Factors