Use of recombinant factor VIIa for massive postpartum haemhorrage: case series and review of literature.
Recombinant activated factor VII is indicated mainly for the treatment of patients with haemophilia inhibitors. It has also been found successful in the treatment of platelet disorder Glanzmann's thrombasthenia. Recently, its use in trauma patients and in patients with intracereberal haemorrhage has become well established. We present three cases of massive post partum haemorrhage treated with rFVIIa, following caesarean section. The response of these three patients is discussed along with review of literature.
Shamsi
Tahir Sultan
TS
Bismillah Taqee Institute of Health Sciences, Karachi.
Hossain
Nazli
N
Soomro
Nargis
N
Hasan
Jahan Ara
JA
Noorani
Mehar
M
Kazi
Sara
S
Quraishy
Mohammed Saeed
MS
Jameel
Bilal
B
Sultan
Syed Tipu
ST
Haider
Saeeda
S
D000328:Adult; D002585:Cesarean Section; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006473:Postpartum Hemorrhage / Q000188:drug therapy*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use*
D011994:Recombinant Proteins; D015942:Factor VIIa