Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy.
Ectopic pregnancies that fail methotrexate therapy are predominantly euploid by comparative genomic hybridization (CGH). This feasibility study also confirms that formalin-fixed paraffin-embedded gestational tissue can successfully undergo CGH.
McKenzie
Laurie Jane
LJ
Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA. ljmckenzie@pol.net
El-Zimaity
Hala
H
Krotz
Stephan
S
Laucirica
Rodolfo
R
Carson
Sandra
S
Buster
John E
JE
D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D009693:Nucleic Acid Hybridization / Q000379:methods; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy* / Q000235:genetics*; D012189:Retrospective Studies; D017211:Treatment Failure
D008727:Methotrexate