title: [Hemorrhagic dengue fever after trip to Malaysia].
abstract: A 39-year-old patient developed a disseminated rash with scattered petechiae, fever, malaise and arthralgia after a trip to Malaysia. The patient displayed increasing dengue IgG titers and borderline dengue IgM titers. Dengue fever with a hemorrhagic course is a rare condition in adult patients. Patients who have previously had dengue fever and retained non-neutralizing heterotypic antibodies are more likely to develop this complication via the phenomenon of antibody-dependent enhancement.
authors.affiliation: Klinik und Poliklinik für Dermatologie der Universität Regensburg. christian.hafner@klinik.uni-regensburg.de
authors.forename: C
authors.initials: C
authors.lastname: Hafner
authors.forename: K
authors.initials: K
authors.lastname: Koellner
authors.forename: T
authors.initials: T
authors.lastname: Vogt
authors.forename: M
authors.initials: M
authors.lastname: Landthaler
authors.forename: R-M
authors.initials: RM
authors.lastname: Szeimies
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003716:Dengue Virus / Q000276:immunology; D003937:Diagnosis, Differential; D005858:Germany; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008296:Malaysia; D008297:Male; D019595:Severe Dengue / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D014195:Travel
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M