title: Age modulates the effects of sleep restriction in women.
abstract: OBJECTIVE
  To investigate how age influences the effects of 3 nights of sleep restriction in healthy women.
  
  
  METHODS
  After a baseline night, sleep was restricted to 4 hours during 3 consecutive nights. One recovery night followed the sleep restriction.
  
  
  METHODS
  The sleep-restriction experiments were conducted under standardized conditions with continuous electroencephalographic ambulatory recordings. Before entering the study, the subjects underwent a polysomnographic recording for exclusion of sleep disorder and adaptation to the laboratory environment.
  
  
  METHODS
  Eleven young women (aged 20-30 years) and 10 older women (aged 55-65 years) were included in the study.
  
  
  METHODS
  The subjects were admitted to the sleep laboratory for 5 consecutive nights and days. After 1 baseline night, 3 nights of sleep restriction to 4 hours were performed and were followed by 1 recovery night of 8 hours. Continuous ambulatory electroencephalographic recordings were performed, as well as the Maintenance of Wakefulness Test (8:30 AM and 1:30 PM), the Stanford Sleepiness Scale, and the Psychomotor Vigilance Test.
  
  
  RESULTS
  Young women were more affected by sleep restriction than were the older women. This was evidenced by more sleep onsets during the Maintenance of Wakefulness Test sessions in the young subjects, who also rated themselves more sleepy than the older women.
  
  
  CONCLUSIONS
  Age influences the impact of sleep restriction on vigilance in women.
authors.affiliation: Sleep Laboratory, CHU de Charleroi, Vesale Hospital, University of Brussels, Belgium.
authors.forename: Patricia
authors.initials: P
authors.lastname: Stenuit
authors.forename: Myriam
authors.initials: M
authors.lastname: Kerkhofs
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D001143:Arousal; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008875:Middle Aged; D017286:Polysomnography; D011597:Psychomotor Performance; D011930:Reaction Time; D012892:Sleep Deprivation / Q000453:epidemiology*; D012895:Sleep, REM / Q000502:physiology; D011795:Surveys and Questionnaires; D014851:Wakefulness / Q000502:physiology