title: Three-year follow-up of biomicroscopy signs and refractive status in patients wearing lotrafilcon A lenses.
abstract: OBJECTIVE
  To report the wearer experience, biomicroscopy signs, and stability of refractive error after 3 years' use of lotrafilcon A lenses.
  
  
  METHODS
  Seventy-four subjects from a multicenter clinical trial with lotrafilcon A lenses were queried on aspects of lens wear. Biomicroscopy signs and refractive error were compared to baseline measurements.
  
  
  RESULTS
  A total of 66% of subjects reported continuing to wear lotrafilcon A lenses, usually for more than 21 nights, with high satisfaction. Signs of limbal, palpebral, and bulbar redness improved significantly. Average refractive error remained stable.
  
  
  CONCLUSIONS
  Long-term use of lotrafilcon A lenses resulted in high wearer satisfaction, reduction of ocular redness, and stable refractive error.
authors.affiliation: CIBA Vision Corporation, Duluth, GA 30097, USA. bill.cibavision.novartis.com
authors.forename: Bill
authors.initials: B
authors.lastname: Long
authors.forename: Florence
authors.initials: F
authors.lastname: Malet
authors.forename: Marie
authors.initials: M
authors.lastname: Lejeune
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: George-Vicariot
authors.forename: Roland
authors.initials: R
authors.lastname: Pagot
authors.forename: Catherine
authors.initials: C
authors.lastname: Peyre
authors.forename: Xavier
authors.initials: X
authors.lastname: Subirana
mesh_terms: D003262:Contact Lenses, Extended-Wear; D003315:Cornea / Q000166:cytology*; D018592:Cross-Over Studies; D005500:Follow-Up Studies; D006801:Humans; D020100:Hydrogels; D017060:Patient Satisfaction; D012029:Refraction, Ocular / Q000502:physiology*; D012030:Refractive Errors / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D012828:Silicones; D013997:Time Factors; D014792:Visual Acuity; D005466:Fluorocarbons
chemical_list: D020100:Hydrogels; D012828:Silicones; C481129:lotrafilcon A; D005466:Fluorocarbons