title: Mifepristone may inhibit the midcycle gonadotropin surge at both ovarian and pituitary sites of action.
abstract: The ability of mifepristone to delay ovulation is thought to be based on the antigonadotropic effects of the drug. In the current work, late-follicular phase administration of mifepristone resulted in decrease in both circulating FSH and inhibin B, suggesting both central and ovarian sites of action.
authors.affiliation: Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland. oskari.heikinheimo@helsinki.fi
authors.forename: Oskari
authors.initials: O
authors.lastname: Heikinheimo
authors.forename: Riikka
authors.initials: R
authors.lastname: Leminen
authors.forename: Taneli
authors.initials: T
authors.lastname: Raivio
mesh_terms: D005260:Female; D005498:Follicular Phase / Q000097:blood / Q000187:drug effects*; D006062:Gonadotropins / Q000097:blood*; D006801:Humans; D015735:Mifepristone / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects* / Q000378:metabolism; D010902:Pituitary Gland / Q000187:drug effects* / Q000378:metabolism
chemical_list: D006062:Gonadotropins; D015735:Mifepristone