[MGAP-A microbe genome annotation platform].
A Microbe Genome Annotation Platform (MGAP) was developed and applied to the cynobacterium PCC7002 genome annotation. Various bioinformatics software tools from sequence analysis to gene identification and function prediction were implemented in MGAP. Protein sequence databases SWISSPROT and PDBseq, protein information resource InterPro and COG were also integrated in the platform. The web interface of MGAP has the functionality to display a circular map of gene distribution and GC contents throughout the genome. Detailed information such as the DNA and protein sequence, the location of genes on chromosomes can be viewed by clicking the corresponding object within the map. MGAP is based on a PC/Linux system affordable for small biological laboratories and has the advantage of using free software tools including MySQL, Apache and Perl.
Yu
Zhou
Z
College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Centre of Bioinformatics, Peking University, Beijing 100871, China. yuzhou@hkuce.hku.hk
Li
Tao
T
Cai
Tao
T
Zhao
Jindong
J
Luo
Jingchu
J
D000458:Cyanobacteria / Q000235:genetics*; D030541:Databases, Genetic; D016680:Genome, Bacterial; D020407:Internet; D012984:Software; D014584:User-Computer Interface