5-Methoxypropacin, a novel coumarinolignoid from Protium unifoliolatum.
The novel coumarinolignoid 5-methoxypropacin was isolated from the ethereal extract of the wood of the Amazonian species Protium unifoliolatum. Its structure was elucidated by spectroscopic methods as IR, 1D and 2D (1)H, (13)C-NMR and mass spectrometry. The regioisomer and the position of coumarin and arylpropanoid coupling were determined by long-distance C-H correlation (HMBC) and NOE experiments. Scopoletin and beta-sitosterol were also isolated and identified by the same physical methods.
Magalhães
Alvicler
A
Laboratório de Química de Produtos Naturais, Instituto de Tecnologia em Fármacos, FIOCRUZ, R. Sizenando Nabuco 100, 21041-250 Rio de Janeiro, RJ, Brazil.
Zoghbi
Maria Das G B
MD
Siani
Antonio C
AC
D029403:Burseraceae / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
C508657:5-methoxypropacin; D003374:Coumarins