title: [Evaluation on cytotoxicity of a new nano-hydroxyapatite as root canal filling sealer].
abstract: OBJECTIVE
  To evaluated the cytotoxicity of a new nano-hydroxyapatite (n-HA) root canal sealer.
  
  
  METHODS
  In this study, the cytotoxicity was evaluated by the method of MTT assay in vitro, and culture medium F12 as control, three concentrations of the soaking material cultured with mouse osteoblast separately, to test the cell relative growth rate (RGR) of every group.
  
  
  RESULTS
  The toxicity graduation of the n-HA root canal sealer tends to 0 with the culture time increasing. The cell survival rate of n-HA root canal sealer showed high relatively. The OD value of cell was similar for the negative control and the extracts (P > 0.05).
  
  
  CONCLUSIONS
  The result indicated that n-HA root canal sealer was compatible with the testcells.
authors.affiliation: Dept. of Endodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Li-ying
authors.initials: LY
authors.lastname: Xiao
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Hong
authors.initials: H
authors.lastname: Tan
authors.forename: Yun-mao
authors.initials: YM
authors.lastname: Liao
authors.forename: Ming-long
authors.initials: ML
authors.lastname: Yuan
mesh_terms: D000818:Animals; D002470:Cell Survival; D003786:Dental Pulp Cavity; D017886:Durapatite; D051379:Mice; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement
chemical_list: D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; C112894:canals sealer; D017886:Durapatite