title: Use of a skin adhesive (octyl-2-cyanoacrylate) and the optimum reinforcing combination for suturing wounds.
abstract: The adhesion strength of a skin adhesive, octyl-2-cyanoacrylate (Dermabond), was measured under various conditions using porcine skin. The combined use of a skin adhesive and a skin closure tape (n = 5) was significantly stronger than a single application of skin adhesive (n = 5) (p < 0.01). We have tentatively named the wound closure in which a skin adhesive and reinforcement material were combined the Reinforcing Combination Method. To obtain optimum conditions, further studies were done for sequence of application, type of reinforcement material, a number of layers, and width of the suture. The optimum condition for the reinforcement combination was established by applying one layer of skin adhesive over a skin closure tape, over one layer of skin adhesive, with a suture width of 4 cm. This reinforcement combination might be useful in clinical practice.
authors.affiliation: Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Fuzoku-chiba-hokuso Hospital, Chiba, Japan. mc@nms.ac.jp
authors.forename: Miho
authors.initials: M
authors.lastname: Chigira
authors.forename: Masataka
authors.initials: M
authors.lastname: Akimoto
mesh_terms: D000818:Animals; D001458:Bandages; D003487:Cyanoacrylates / Q000494:pharmacology*; D062109:Dermatologic Surgical Procedures; D023421:Models, Animal; D011126:Polypropylenes; D013526:Surgical Mesh; D013536:Suture Techniques; D013552:Swine; D013718:Tensile Strength; D014014:Tissue Adhesives / Q000494:pharmacology*
chemical_list: D003487:Cyanoacrylates; D011126:Polypropylenes; D014014:Tissue Adhesives