title: The nature of the remaining dentin surface following application of Carisolv solution.
abstract: OBJECTIVE
  To evaluate the effect of Carisolv solution on the topography and surface hardness of dentin.
  
  
  METHODS
  Two separate studies were carried out. Atomic force microscopy (AFM) was employed to visualize dentin surface topography on slices of previously extracted non-carious and carious teeth following the passive application of Carisolv gel for 30- and 60-second periods. A Wallace hardness instrument was used to measure the dentin surface hardness following active caries removal with Carisolv gel and the specially designed instruments. Conventional caries removal with dental burs and non-carious dentin acted as controls for the latter study.
  
  
  RESULTS
  AFM revealed that the passive application of Carisolv gel resulted in smoother surfaces than observed on carious and non-carious dentin. There was a statistically significant difference between the mean hardness values for non-carious and Carisolv-treated dentin (P< 0.05). There was no statistically significant difference between the non-carious and bur-treated dentin nor the Carisolv and bur-treated dentin.
authors.affiliation: Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, United Kingdom. Leean.Morrow@ntlworld.com
authors.forename: Leean A
authors.initials: LA
authors.lastname: Morrow
authors.forename: Nairn H F
authors.initials: NH
authors.lastname: Wilson
authors.forename: David C
authors.initials: DC
authors.lastname: Watts
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Silikas
mesh_terms: D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000494:pharmacology*; D003731:Dental Caries / Q000628:therapy; D003737:Dental Cavity Preparation / Q000295:instrumentation / Q000379:methods*; D003804:Dentin / Q000187:drug effects*; D018698:Glutamic Acid / Q000494:pharmacology*; D006244:Hardness / Q000187:drug effects; D006801:Humans; D007930:Leucine / Q000494:pharmacology*; D008239:Lysine / Q000494:pharmacology*; D018625:Microscopy, Atomic Force; D013499:Surface Properties / Q000187:drug effects
chemical_list: D002327:Cariostatic Agents; C119934:Carisolv; D018698:Glutamic Acid; D007930:Leucine; D008239:Lysine