title: Use of recombinant factor VIIa for massive postpartum haemhorrage: case series and review of literature.
abstract: Recombinant activated factor VII is indicated mainly for the treatment of patients with haemophilia inhibitors. It has also been found successful in the treatment of platelet disorder Glanzmann's thrombasthenia. Recently, its use in trauma patients and in patients with intracereberal haemorrhage has become well established. We present three cases of massive post partum haemorrhage treated with rFVIIa, following caesarean section. The response of these three patients is discussed along with review of literature.
authors.affiliation: Bismillah Taqee Institute of Health Sciences, Karachi.
authors.forename: Tahir Sultan
authors.initials: TS
authors.lastname: Shamsi
authors.forename: Nazli
authors.initials: N
authors.lastname: Hossain
authors.forename: Nargis
authors.initials: N
authors.lastname: Soomro
authors.forename: Jahan Ara
authors.initials: JA
authors.lastname: Hasan
authors.forename: Mehar
authors.initials: M
authors.lastname: Noorani
authors.forename: Sara
authors.initials: S
authors.lastname: Kazi
authors.forename: Mohammed Saeed
authors.initials: MS
authors.lastname: Quraishy
authors.forename: Bilal
authors.initials: B
authors.lastname: Jameel
authors.forename: Syed Tipu
authors.initials: ST
authors.lastname: Sultan
authors.forename: Saeeda
authors.initials: S
authors.lastname: Haider
mesh_terms: D000328:Adult; D002585:Cesarean Section; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006473:Postpartum Hemorrhage / Q000188:drug therapy*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use*
chemical_list: D011994:Recombinant Proteins; D015942:Factor VIIa