[Occupational allergy to mugwort].
BACKGROUND
Mugwort (Artemisia vulgaris) has traditionally been used as a spice, vegetable and as a herbal medicine. The main representatives of the Artemisia family besides Artemisia vulgaris include Artemisia absinthum and Artemisia dracunculus (estragon). Mugwort pollen allergens are important in triggering late summer and fall pollinosis; in addition cross reactivity occurs between Artemisia vulgaris pollen allergens and celery, carrottes and certain spices belonging to the family of Umbelliferae.


METHODS
A florist with a pre-existing sunflower allergy developed a life-threatening glottal edema after occupational contact with mugwort. She did not suffer from an oral allergy syndrome towards mugwort pollen cross allergens.


RESULTS
Skin testing (prick and scratch testing) revealed a strong sensitisation against mugwort and estragon. Specific IgE antibodies against mugwort, sunflower, carrots, celery, fennel and anis were elevated in the peripheral blood.


CONCLUSIONS
The observation of a severe mugwort allergy with life-threatening complications in a florist underscores the high allergenic potential of Artemisia vulgaris and documents for the first time the occupational significance of this allergy.
Kurzen
Marina
M
Klinik für Dermatologie, Venerologie und Allergologie am Klinikum Mannheim gGmbH, Universitätsklinikum der Ruprecht-Karls-Universität Heidelberg. Marina.Kurzen@haut.ma.uni-heidelberg.de
Bayerl
Christiane
C
Goerdt
Sergij
S
D000328:Adult; D019306:Artemisia / Q000009:adverse effects*; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D007819:Laryngeal Edema / Q000139:chemically induced* / Q000175:diagnosis*; D012221:Rhinitis, Allergic, Perennial / Q000139:chemically induced* / Q000175:diagnosis*