DNA analysis in microfabricated formats.
The use of microfabricated DNA analysis tools utilizing microfluidics will provide the next generation of inexpensive DNA diagnostics. It will also provide methodologies to measure gene expression in a massively parallel manner, eventually providing the methodologies to measure most or all the human genes of significance on a single chip. These technologies, including PCR analysis, electrophoresis and gene chips are described using examples from the archival literature.
Abramowitz
S
S
Advanced Technology Program, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.