title: Mechanical heart valve cavitation.
abstract: Cavitation was first directly related to mechanical heart valves in the mid 1980s after a series of valve failures observed with the Edwards-Duromedics valve. The damages observed indicated that cavitation could be responsible. Later, several in vitro studies visualized the bubble formation and collapse of cavitation at mechanical heart valves. It was suggested that cavitation could also cause damage to the formed elements of blood and thereby enhance the risk of thromboembolic complications seen in mechanical heart valve patients. Therefore, an applicable technique for in vivo detection of cavitation is required. This article reviews techniques developed for in vivo detection of cavitation and suggests focus for future studies.
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, Research Unit, Aarhus University Hospital, Skejby Sygehus, Brendstrupgaardsvej, 8200 Aarhus N, Denmark. peter.johansen@ki.au.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Johansen
mesh_terms: D017076:Computer-Aided Design; D019544:Equipment Failure Analysis / Q000379:methods*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008955:Models, Cardiovascular; D011474:Prosthesis Design / Q000379:methods* / Q000639:trends; D011475:Prosthesis Failure; D012107:Research Design; D013923:Thromboembolism / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control*