Protein/polysaccharide cogel formation based on gelatin and chemically modified schizophyllan.
In the work, aldehyde groups were quantitatively introduced into schizophyllan (SPG) side chains through periodate oxidation. The periodate-oxidized SPG (POSPG) forms an elastic gel with gelatin. The cogel formation is based on the Schiff-base reaction between the amino groups of gelatin chains and the aldehyde groups of POSPG chains. The POSPG/gelatin cogel has an elastomeric character with a very small value of loss tangent. The gelation kinetics and gel properties were discussed as a function of POSPG concentration, gelatin concentration, oxidation degree, temperature, and pH. This method can be used to design a large variety of cogels between SPG and proteins.
Fang
Yapeng
Y
Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, Sumiyoshi, Osaka, 558-8585, Japan.
Takahashi
Rheo
R
Nishinari
Katsuyoshi
K
D000276:Adjuvants, Immunologic / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D001704:Biopolymers / Q000737:chemistry*; D002417:Cattle; D003432:Cross-Linking Reagents / Q000737:chemistry; D005780:Gelatin / Q000737:chemistry*; D005782:Gels / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D046911:Macromolecular Substances / Q000737:chemistry*; D008956:Models, Chemical; D008962:Models, Theoretical; D010100:Oxygen / Q000737:chemistry; D010504:Periodic Acid / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry*; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry; D012566:Sizofiran / Q000737:chemistry*; D013696:Temperature; D013816:Thermodynamics; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000447:Aldehydes; D001672:Biocompatible Materials; D001704:Biopolymers; D003432:Cross-Linking Reagents; D005782:Gels; D046911:Macromolecular Substances; D004364:Pharmaceutical Preparations; D011108:Polymers; D011134:Polysaccharides; D011506:Proteins; D010504:Periodic Acid; D012566:Sizofiran; D005780:Gelatin; C009288:metaperiodate; D010100:Oxygen