title: [A clinical study of hepatic arterial infusion chemotherapy with low-dose CDDP and 5-FU for liver metastases].
abstract: We followed patients who underwent hepatic arterial infusion chemotherapy with low-dose CDDP+5-FU for liver metastases from colorectal cancer in the outpatient setting. A catheter was inserted from the femoral artery into the proper hepatic artery using the interventional technique. Two complete response (CR) and seven partial response (PR) were achieved, but later 2 of these patients had lung metastases. We conclude that this therapy may be effective, but control of extrahepatic lesions is necessary for life prolongation.
authors.affiliation: Dept. of Gastroenterological Surgery, Shimonoseki Welfare Social Hospital.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yonemitsu
authors.forename: Shigenori
authors.initials: S
authors.lastname: Sugihara
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Toyama
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tsuruta
authors.forename: Kenichi
authors.initials: K
authors.lastname: Teshima
authors.forename: Mutsuo
authors.initials: M
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D015179:Colorectal Neoplasms / Q000473:pathology*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D015996:Survival Rate
chemical_list: D002945:Cisplatin; D005472:Fluorouracil