title: IBX-mediated alpha-hydroxylation of alpha-alkynyl carbonyl systems. A convenient method for the synthesis of tertiary alcohols.
abstract: [reaction: see text] IBX (o-iodoxybenzoic acid) is an excellent reagent for the alpha-hydroxylation of alpha-alkynyl carbonyl compounds without giving dehydrogenation products. The convenient procedure proves to be useful for the construction of a variety of tertiary alcohols (55-91%) under mildly acidic conditions.
authors.affiliation: Department Chemie, Technische Universität München, Lichtenbergstr. 4, D-85747 Garching, Germany. stefan.kirsch@ch.tum.de
authors.forename: Stefan F
authors.initials: SF
authors.lastname: Kirsch