title: A high-yield, one-step synthesis of o-phenylene ethynylene cyclic trimer via precipitation-driven alkyne metathesis.
abstract: [reaction: see text] A shape-persistent, conjugated o-phenylene ethynylene cyclic trimer was prepared in one step from tetrasubstituted benzene monomer 4 in 86% isolated yield through precipitation-driven alkyne metathesis. The template-free, selective generation of the molecular triangle 5 is a thermodynamically favored process and under equilibrium control. A novel tetrameric macrocycle 7 was generated via scrambling metathesis between tricycle 5 and hexacycle 6 using this dynamic covalent chemistry.
authors.affiliation: Roger Adams Laboratory, Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Scott M
authors.initials: SM
authors.lastname: Brombosz
authors.forename: Jose L
authors.initials: JL
authors.lastname: Mendoza
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Moore