The neonatal tear film.
The importance of the tear film for the integrity of the ocular surface is well established. Full-term neonates produce tears normally, but low spontaneous blink rates during early life raises important questions regarding tear dynamics and stability. Although an afferent neural pathway that could potentially detect tear break-up is in place at birth, there is indirect evidence that the neonatal tear film is adapted to resist evaporation-mediated tear thinning. This adaptation presumably prevents drying of the ocular surface during long inter-blink periods. However, low rates of tear turnover may have important implications for the defence of the eye against potential pathogens.
Lawrenson
John G
JG
Department of Optometry and Visual Science, City University, London, EC1V 0HB, UK.
Murphy
Paul J
PJ
Esmaeelpour
Marieh
M