title: Applications of capillary electrophoresis on microchip.
abstract: CE on microchip is an emerging separation technique that has attracted wide attention and gained considerable popularity. Because of miniaturization of the separation format, CE on chip typically offers shorter analysis time and lower reagent consumption with potential development of portable analytical instrumentation. This review with 143 references is focused on proteins and peptides analysis, DNA separation including fragment sizing, genotyping, mutation detection and sequencing, and also the analysis of low-molecular-weight compounds, namely explosive residues and warfare agents, pharmaceuticals and drugs of abuse, and various small molecules in body fluids.
authors.affiliation: Alcor BioSeparations, Santa Clara, CA 95051, USA. ladia@dolnik.net
authors.forename: Vladislav
authors.initials: V
authors.lastname: Dolnik
authors.forename: Shaorong
authors.initials: S
authors.lastname: Liu
mesh_terms: D002846:Chromatography, Affinity; D004252:DNA Mutational Analysis; D019075:Electrophoresis, Capillary; D015180:Electrophoresis, Gel, Two-Dimensional; D007525:Isoelectric Focusing; D046228:Microarray Analysis; D011506:Proteins / Q000032:analysis / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
chemical_list: D011506:Proteins