A case of amicrobial pustulosis of the folds associated with neutrophilic gastrointestinal involvement in systemic lupus erythematosus.
BACKGROUND
Amicrobial pustulosis of the folds is a recently described entity characterized by relapsing pustular lesions involving predominantly the cutaneous folds and the scalp. The disease typically occurs in the context of an autoimmune or systemic disease and should be included within the spectrum of neutrophilic dermatoses.


METHODS
We describe a patient with a history of systemic lupus erythematosus, who developed amicrobial pustulosis of the folds. Strikingly, the patient also exhibited recurrent oral and gastrointestinal manifestations that paralleled the course of the cutaneous signs.


CONCLUSIONS
Our observation indicates that, in analogy to the other neutrophilic dermatoses, amicrobial pustulosis of the folds can also be complicated by the development of extracutaneous neutrophilic involvement, knowledge of which is critical for its diagnosis and proper management.
Kerl
K
K
Department of Dermatology, University Medical School, Geneva, Switzerland.
Masouyé
I
I
Lesavre
P
P
Saurat
J-H
JH
Borradori
L
L
D000328:Adult; D005260:Female; D005499:Folliculitis / Q000473:pathology; D005500:Follow-Up Studies; D005767:Gastrointestinal Diseases / Q000473:pathology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology; D019226:Oral Ulcer / Q000473:pathology; D012002:Rectal Diseases / Q000473:pathology; D012810:Sigmoid Diseases / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*; D014456:Ulcer / Q000473:pathology