Angiogenesis in lymphoma: a short review.
It is now well established that the growth of primary and metastatic tumors is associated with the formation of new blood vessels, and that the growth of these tumor cells is frequently dependent on this neovasculature. The observation that inhibition of tumor angiogenesis in mice can lead to tumor regression or dormancy generated high level of enthusiasm and interest in developing new treatment strategies for human cancer based on inhibiting tumor angiogenesis. This short review focuses on recent advances in angiogenesis-research in non-Hodgkin's lymphoma and Hodgkin's disease.
Younes
Anas
A
Department of Lymphoma/Myeloma, M.D. Anderson Cancer Center, Houston, TX 77030, USA. ayounes@mdanderson.org
D000818:Animals; D006689:Hodgkin Disease / Q000503:physiopathology; D006801:Humans; D008223:Lymphoma / Q000503:physiopathology*; D008228:Lymphoma, Non-Hodgkin / Q000503:physiopathology; D009389:Neovascularization, Pathologic; D042442:Vascular Endothelial Growth Factors / Q000378:metabolism
D042442:Vascular Endothelial Growth Factors