[Granulomatous dermatitis following herpes zoster with detection of varicella zoster virus DNA].
The occurrence of a granulomatous inflammation following herpes zoster infection is uncommon and its pathogenesis is unclear. A 74-year-old male patient developed multiple red-brown papules following a secondary generalized infection with varicella zoster virus in the same area. The patient was suffering from a chronic lymphocytic B-cell leukaemia. Histopathologically, granulomatous dermatitis with multinucleate giant cells was found. Varicella zoster virus DNA was identified by polymerase chain reaction in the tissue. After a renewed antiviral therapy, skin lesions disappeared completely.
Gesierich
Anja
A
Universität-Hautklinik Würzburg.
Krahl
Dieter
D
Weiss
Harald
H
Bröcker
Eva-Bettina
EB
Rose
Christian
C
D000368:Aged; D004279:DNA, Viral / Q000032:analysis / Q000235:genetics; D003872:Dermatitis / Q000209:etiology* / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000209:etiology* / Q000473:pathology*; D006562:Herpes Zoster / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology*; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D015448:Leukemia, B-Cell / Q000150:complications / Q000473:pathology*
D004279:DNA, Viral