[A case of pancreatic cancer complicated by gemcitabine-induced peripheral edema].
Gemcitabine mono-therapy was carried out in an unresectable pancreatic cancer. After six courses of treatment, pitting edema appeared and gradually became worse especially after gemcitabine infusion. Gemcitabine-induced edema was suspected after exclusion of other causes. Diuretics and steroids were useful to control the peripheral edema in this case, and gemcitabine therapy could be continued.
Shitara
Kohei
K
Dept. of Medical Oncology, Misawa City Hospital.
Ishiguro
Atsushi
A
Munakata
Masaki
M
Sakata
Yuh
Y
Hirata
Nobuto
N
Yabu
Kouji
K
Wada
Ryouichi
R
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D004232:Diuretics / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004487:Edema / Q000139:chemically induced* / Q000188:drug therapy; D005665:Furosemide / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage; D013148:Spironolactone / Q000008:administration & dosage; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D004232:Diuretics; D003841:Deoxycytidine; D013148:Spironolactone; D005665:Furosemide; D011239:Prednisolone; D000093542:Gemcitabine