[Usefulness of fetal biophysical profile in preterm rupture of membranes with treatment].
OBJECTIVE
To evaluate the usefulness of the fetal biophysical profile as a predictor of early neonatal infection in patients with preterm rupture of membranes in conservative management.


METHODS
This is a validation study of a diagnostic test. Between November, 2001 and August, 2003, 75 patients with 27 to 33 weeks of gestation and preterm rupture of membranes in conservative management were studied. Daily, a fetal biophysical profile was applied to them. Statistical analysis was done with chi square test and with a 2 x 2 contingency table that compared the biophysical score of + 8 and < or = 6 versus the presence or absence of early neonatal infection.


RESULTS
The biophysical score < or = 6 was associated with early neonatal infection (p < 0.05), with sensitivity, specificity, positive and negative predictive values of 80, 85, 64 and 85%, respectively (OR 9.73, 95% CI: 2.88-34.63; p = 0.0000164).


CONCLUSIONS
The biophysical score < or = 6 was significantly associated with early neonatal infection.
Romero Arauz
Juan Fernando
JF
Departamento de Medicina Perinatal, Hospital de Ginecología y Obstetricia Luis Castelazo Ayala, Instituto Mexicano del Seguro Social, México, DF. jfromarauz@hotmail.com
Martínez Chéquer
Juan Carlos
JC
Alonso López
Angel García
AG
Jurado Hernández
Víctor Hugo
VH
Ayala Méndez
José Antonio
JA
D000293:Adolescent; D000328:Adult; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D005323:Fetal Monitoring; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D007239:Infections / Q000175:diagnosis*; D011247:Pregnancy; D011379:Prognosis