title: Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy.
abstract: Ectopic pregnancies that fail methotrexate therapy are predominantly euploid by comparative genomic hybridization (CGH). This feasibility study also confirms that formalin-fixed paraffin-embedded gestational tissue can successfully undergo CGH.
authors.affiliation: Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA. ljmckenzie@pol.net
authors.forename: Laurie Jane
authors.initials: LJ
authors.lastname: McKenzie
authors.forename: Hala
authors.initials: H
authors.lastname: El-Zimaity
authors.forename: Stephan
authors.initials: S
authors.lastname: Krotz
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Laucirica
authors.forename: Sandra
authors.initials: S
authors.lastname: Carson
authors.forename: John E
authors.initials: JE
authors.lastname: Buster
mesh_terms: D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D009693:Nucleic Acid Hybridization / Q000379:methods; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy* / Q000235:genetics*; D012189:Retrospective Studies; D017211:Treatment Failure
chemical_list: D008727:Methotrexate