[Correlation of newborn hemolytic disease with ABO antibodies in sera of pregnant women].
To investigate the relations between morbidity of hemolytic diseases of newborn and ABO antibodies (HDN) in sera of Han and Yao nationality, pregnant women were examined before and after delivery. Antibodies screen, direct antiglobulin test, free antibodies and elution test were all performed. The results indicated that immunologic ABO antibodies of Han people were found in 673 cases out of 1,471 Han pregnant women, and was also found in 28 cases out of 65 Yao pregnant women, and there was no significant difference of incidences between Han and Yao nationality. 31 cases of HDN were found out of 288 newborn in Han and 3 cases of HDN were found out of 25 newborn in Yao, and there was no significant difference between Han and Yao nationalities. The characteristics of HDN in Han nationality were as same as in Yao nationality. In conclusion, the morbidity of HDN in Han and Yao nationalities of Shaoguan area did not showed essential difference, the immunologic ABO antibodies and its titration test, especially, elution test are important for prognosis of HDN.
Yang
Shao-Ming
SM
Shaoguan Blood Center, Shaoguan 512026, China. SGYSM@126.com
Wu
Qiao-Ying
QY
Luo
Hong-Qing
HQ
Lan
Jiong-Cai
JC
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D001787:Blood Group Incompatibility / Q000097:blood / Q000151:congenital; D002681:China; D004899:Erythroblastosis, Fetal / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011379:Prognosis
D000017:ABO Blood-Group System; D007074:Immunoglobulin G