title: Laboratory bio-assay of temephos and fenthion against some vector species of public health importance.
abstract: Laboratory studies carried out using Temephos and Fenthion, two commonly used larvicides under Urban Malaria Scheme (NMEP) and NFCP for the control of mosquito larvae. The results revealed that the LC50 and LC90 values for temephos against Aedes aegypti 0.0177 and 0.0559, Anopheles stephensi 0.0148 and 0.0472, Culex quinquefasciatus 0.0157 & 0.0480 and for Culex vishnui group of mosquitoes 0.043 & 0.0118 ppm respectively. The results obtained revealed that there is a 62.8 & 94.12 times increase in the LC50 & LC90 of Cx. Quinquefasciatus which indicates that the species has developed resistance to temephos. There were 6.32 & 8.34 fold increase in Ae. aegypti and 2.27 & 2.34 fold increase in LC50 & LC90 values of An. stephensi are indicative of development of tolerance against temephos. Similarly LC50 and LC90 values estimated for fenthion against Ae. aegypti 0.0173 & 0.0392, An. stephensi 0.0274 & 0.0992 and Cx. quinquefasciatus 0.03 & 0.0469 respectively. The slope values were found to be higher in fenthion as compared to temephos. It was recorded to be 2.72 times higher in Cx. quinquefasciatus and 1.54 times against An. stephensi. However, much difference was not observed in the slope values of temephos and fenthion in Ae. aegypti.
authors.affiliation: National Institute of Communicable Diseases, 22- Shamnath Marg, Delhi.
authors.forename: Kalpana
authors.initials: K
authors.lastname: Baruah
mesh_terms: D000330:Aedes / Q000187:drug effects / Q000254:growth & development; D000818:Animals; D000852:Anopheles / Q000187:drug effects / Q000254:growth & development; D001681:Biological Assay; D003465:Culex / Q000187:drug effects / Q000254:growth & development; D009033:Culicidae / Q000187:drug effects* / Q000254:growth & development; D005284:Fenthion / Q000494:pharmacology*; D007303:Insect Vectors / Q000187:drug effects*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects*; D009032:Mosquito Control / Q000379:methods*; D000002:Temefos / Q000494:pharmacology*
chemical_list: D007306:Insecticides; D005284:Fenthion; D000002:Temefos