title: A pen injection device for self-administration of recombinant follicle-stimulating hormone for fertility treatments.
abstract: A pen injection device modeled on the insulin pen used by diabetic patients has been introduced to deliver recombinant follicle-stimulating hormone to women undergoing controlled ovarian stimulation for in vitro fertilization or other forms of assisted reproductive technology. The pen device makes it easier and less painful for women to self-administer daily injections. The high precision and accuracy of the device enables physicians to fine-tune dosage. The woman simply inserts the multidose cartridge into the Puregon (Follistim) Pen, attaches a BD Micro-Fine Pen Needle, selects the prescribed dose on the dial at the base of the pen, inserts the needle subcutaneously and pushes the injection button to administer the injection. A fresh needle is used for each injection.
authors.affiliation: Reproductive Science Center of Boston, One Forbes Road, Lexington, MA 02421-7305, USA. Samuel.Pang@IntegraMed.com
authors.forename: Samuel C
authors.initials: SC
authors.lastname: Pang
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D005299:Fertility Agents / Q000008:administration & dosage*; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage* / Q000235:genetics; D006801:Humans; D007279:Injections, Subcutaneous / Q000295:instrumentation*; D010062:Ovulation Induction / Q000295:instrumentation* / Q000379:methods; D011994:Recombinant Proteins / Q000008:administration & dosage; D027724:Reproductive Techniques, Assisted / Q000295:instrumentation*; D012646:Self Administration / Q000295:instrumentation*; D013594:Syringes
chemical_list: D005299:Fertility Agents; D011994:Recombinant Proteins; D005640:Follicle Stimulating Hormone