Evaluation of solution and solid-phase approaches to the synthesis of libraries of alpha,alpha-disubstituted-alpha-acylaminoketones.
Solid phase, solution, and hybrid approaches to the synthesis of small focused libraries of alpha,alpha-disubstituted-alpha-acylaminoketones have been explored. Solution and hybrid approaches that used support-bound reagents and scavenger resins were the most productive.
Garcia
Javier
J
Department of Organic Chemistry, University of Barcelona, 08028-Barcelona, Spain.
Mata
Ernesto G
EG
Tice
Colin M
CM
Hormann
Robert E
RE
Nicolas
Ernesto
E
Albericio
Fernando
F
Michelotti
Enrique L
EL