[New biochemical and molecular aspects of estrogen's action].
Estrogens have several biologic actions. The specific nuclear actions of estrogens are determined by the hormone structure, the isoform subtype of the involved estrogen receptor, the characteristics of the target gene promoter, and the balance between coactivator and corepressor proteins that modulate the final transcriptional response of the complex between estrogens and its receptors. In this review we focus on the new biochemical and molecular aspects of the estrogens action.
Teppa Garrán
Alejandro D
AD
Departamento de Andrología, Clínica El Avila, Caracas, Venezuela.
Terán Dávila
José
J
D004967:Estrogens / Q000494:pharmacology / Q000502:physiology*; D005260:Female; D006801:Humans; D011960:Receptors, Estrogen / Q000187:drug effects / Q000502:physiology
D004967:Estrogens; D011960:Receptors, Estrogen