Biodegradation or metabolism of bisphenol A: from microorganisms to mammals.
Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.
Kang
Jeong-Hun
JH
Department of Applied Chemistry, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka 819-0395, Japan. jrjhkangtcm@mbox.nc.kyushu-u.ac.jp
Katayama
Yoshiki
Y
Kondo
Fusao
F
D000818:Animals; D001419:Bacteria / Q000378:metabolism; D001559:Benzhydryl Compounds; D001673:Biodegradation, Environmental; D005658:Fungi / Q000378:metabolism; D006801:Humans; D008322:Mammals / Q000378:metabolism; D010636:Phenols / Q000378:metabolism*; D010933:Plankton / Q000378:metabolism; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds