Population genetics for Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic minority group in Tibet.
Y-chromosomal STRs loci were analyzed from a sample of 119 healthy unrelated autochthonous male individuals of Chinese Tibetan ethnic minority group using a multiplex PCR system. Allele and haplotype frequencies for DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS438, and DYS439 were determined by the Y-PLEXtrade mark 12 kit. The gene diversity values for the Y-STRs loci ranged from 0.3347 (DYS438) to 0.9547 (DYS385a,b). A total of 110 haplotypes were identified in the Y-STR loci, among which 104 were unique, while six occurred more than once. The overall haplotype diversity for the Y-STRs loci was 0.9981, and the discrimination capacity was 0.9897. The results in the present study can be used for routine forensic application in the region, and enrich Chinese ethnical genetic informational resources.
Zhu
Bofeng
B
Laboratory of Environment and Gene Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an Shaanxi 710061, China. zhubofeng7372@yeah.net
Liu
Shunzhi
S
Ci
Dan
D
Huang
Jingfeng
J
Wang
Youcai
Y
Chen
Liping
L
Zhu
Jun
J
Xu
Yongcheng
Y
Zhao
Qianzi
Q
Li
Shengbin
S
Liu
Yao
Y
D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D018609:Tibet