title: Ornithosaponins A-D, four new polyoxygenated steroidal glycosides from the bulbs of Ornithogalumthyrsoides.
abstract: By analyzing the steroidal glycoside content of fresh bulbs of Ornithogalum thyrsoides (Liliaceae), we were able to isolate four new polyoxygenated steroidal glycosides, which we named ornithosaponins A-D (1-4). The structures of 1-4 were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic or alkaline hydrolysis. The aglycone structure of 1-4 has not been previously reported. It is also notable that ornithosaponins B-D (2-4) have been found to contain 6-deoxy-beta-D-gulopyranose as a sugar component, which is rarely encountered in plant glycosides.
authors.affiliation: Laboratory of Medicinal Pharmacognosy, Tokyo University of Pharmacy and Life Science, School of Pharmacy, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Minpei
authors.initials: M
authors.lastname: Kuroda
authors.forename: Kazutomo
authors.initials: K
authors.lastname: Ori
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Mimaki
mesh_terms: D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D031442:Ornithogalum / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D018514:Plant Structures / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D012503:Saponins; D013256:Steroids; D010100:Oxygen