title: Focus issue: memories of signals past--plastic changes in nervous system function.
abstract: Plasticity encompasses the ability of the nervous system to adapt to injury and the ability of the developing and mature brain to change in response to experience. This week's Special Issue of Science focuses on systems-level approaches to understanding cortical plasticity, especially during development. The accompanying Focus Issue of Science's STKE features articles and resources that address issues related to the molecular changes that underlie synaptic plasticity in response to physiological or pathological stimuli.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Adler
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000502:physiology; D001921:Brain / Q000196:embryology / Q000502:physiology; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D018091:Receptors, AMPA / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate