title: A linchpin approach to unsaturated fatty acids: 11,12-epoxyeicosatrienoic acid and 11S,12S-dihydroxyeicosatrienoic acid ethyl esters.
abstract: [Chemical reaction: See text] A "linchpin" coupling strategy is described for the construction of long-chain fatty acid metabolites. This strategy led to a short synthesis of the ethyl esters of both 11,12-epoxyeicosatrienoic acid (EET) and 11S,12S-dihydroxyeicosatrienoic acid (DHET).
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA. taberdf@@udel.edu
authors.forename: Douglass F
authors.initials: DF
authors.lastname: Taber
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D004952:Esters; D005231:Fatty Acids, Unsaturated / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular
chemical_list: C410128:11,12-dihydroxyeicosatrienoic acid; D004952:Esters; D005231:Fatty Acids, Unsaturated; C046783:11,12-epoxy-5,8,14-eicosatrienoic acid; D015126:8,11,14-Eicosatrienoic Acid