title: MRI and musculoskeletal ultrasonography as diagnostic tools in early arthritis.
abstract: Rheumatoid arthritis (RA) is a chronic and progressive inflammatory disorder primarily affecting the synovium and is characterized by destruction of bone and cartilage. Early diagnosis and treatment of RA can improve disease outcomes substantially. Magnetic resonance imaging and musculoskeletal ultrasonography may facilitate early diagnosis and aid the targeting of intensive therapy. Magnetic resonance imaging and musculoskeletal ultrasonography also are able to monitor temporal changes in disease activity (ie, synovitis) and damage (ie, erosions). These imaging modalities are likely to be increasingly used in the management of early rheumatoid arthritis to ensure the best patient outcomes, although more work is required to determine their optimal roles.
authors.affiliation: Academic Unit of Musculoskeletal Disease, Department of Rheumatology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. hikeen@doctors.org.uk
authors.forename: Helen I
authors.initials: HI
authors.lastname: Keen
authors.forename: Andrew K
authors.initials: AK
authors.lastname: Brown
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Wakefield
authors.forename: Philip G
authors.initials: PG
authors.lastname: Conaghan
mesh_terms: D001168:Arthritis / Q000000981:diagnostic imaging* / Q000473:pathology*; D042241:Early Diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D014463:Ultrasonography / Q000379:methods*