[Effects of extracts of Chinese medicines on Ganoderma lucidum in submerged culture].
Effects of water and ethanol extracts of 10 Chinese medicines, such as Astragalus membranaceus, Coix lachryma-jobi, etc., on biomass and exopolysaccharide of Ganoderma lucidum were studied by submerged culture. The results showed: water extracts of all medicines can improve the culture of G. lucidum except of A. membranaceus, ethanol extracts of C. lachryma-jobi, Dioscorea opposita, Codonopsis pilosula, and Achyranthes bidentata( < 187.5g Medicine/L substrate) can also increase the biomass of G. lucidum, but the ethanol extracts of Angelica sinensis, Dendrobium nobile check the growth of G. lucidum. The production of exopolysa-ccharide can be improved by all the Chinese medicines and their dosage used in this experiment, Although A. sinensis, D. Nobile check the growth of G. lucidum, they could stimulate the secretion of exopolysaccharide in lower dosage. It is concluded that some Chinese medicines, such as C. lachryma-jobi, D. opposita, C. pilosula, etc. can be processed by the fermentation of G. lucidum, and bio-active compound can be produced by adding appropriate Chinese medicine in the substrate to culture G. lucidum.
Yang
Hailong
H
Key Laboratory of Industrial Biotechnology of Ministry of Education, Southern Yangtze University, Wuxi 214036, China. yanghl99@163.com
Wu
Tianxiang
T
Zhang
Kechang
K
D018533:Biomass; D003470:Culture Media / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D046508:Culture Techniques / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D005285:Fermentation / Q000187:drug effects; D011134:Polysaccharides / Q000378:metabolism; D020940:Reishi / Q000187:drug effects* / Q000378:metabolism
D003470:Culture Media; D004365:Drugs, Chinese Herbal; D011134:Polysaccharides