title: Bullous pemphigoid following therapy with an oral beta-blocker.
abstract: A causal relationship is thought to exist between several medications and the development of bullous pemphigoid. Commonly implicated medications include furosemide, penicillins, and ibuprofen. The following is a case report of an elderly man who developed generalized bullous pemphigoid for the first time after beginning therapy with an oral beta-blocker. A literature search revealed only 2 other reports of beta-blocker associated bullous pemphigoid. As both bullous pemphigoid and beta-blockers are common in elderly patients, dermatologists may want to consider beta-blockers as potential etiological agents in the development of bullous pemphigoid.
authors.affiliation: Uniformed Services University of Health Sciences, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Perry
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Sparling
authors.forename: Mark
authors.initials: M
authors.lastname: Pennington
mesh_terms: D000284:Administration, Oral; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D000369:Aged, 80 and over; D003879:Dermatologic Agents / Q000627:therapeutic use; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage / Q000009:adverse effects*; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010391:Pemphigoid, Bullous / Q000139:chemically induced* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D003879:Dermatologic Agents; D008790:Metoprolol; D009173:Mycophenolic Acid; D011241:Prednisone