Orally administered recombinant metallo-beta-lactamase preserves colonization resistance of piperacillin-tazobactam-treated mice.
Stiefel
Usha
U
Harmoinen
Jaana
J
Koski
Pertti
P
Kääriäinen
Susanna
S
Wickstrand
Nina
N
Lindevall
Kai
K
Pultz
Nicole J
NJ
Bonomo
Robert A
RA
Helfand
Marion S
MS
Donskey
Curtis J
CJ
D000284:Administration, Oral; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004357:Drug Synergism; D051379:Mice; D010397:Penicillanic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D010878:Piperacillin / Q000494:pharmacology*; D000078142:Tazobactam; D018440:beta-Lactam Resistance / Q000187:drug effects*; D001618:beta-Lactamases / Q000008:administration & dosage*
D000900:Anti-Bacterial Agents; D010397:Penicillanic Acid; D001618:beta-Lactamases; D000078142:Tazobactam; D010878:Piperacillin