title: Adult onset Still's disease as a cause of acute severe mitral and aortic regurgitation.
abstract: Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly, and serositis. Pericarditis is the most common cardiac manifestation of AOSD and occurs in approximately 30% of cases. A simultaneous occurrence of rapidly progressive bi-valvular regurgitation associated with AOSD has not been previously described. We report a case of a 55-year old woman who underwent mitral valve replacement and Bentall's operation due to acute severe mitral and aortic regurgitation associated with AOSD.
authors.affiliation: Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Jae Seung
authors.initials: JS
authors.lastname: Lee
authors.forename: Il No
authors.initials: IN
authors.lastname: Do
authors.forename: Deok Hyun
authors.initials: DH
authors.lastname: Kang
authors.forename: Seok Jung
authors.initials: SJ
authors.lastname: Joo
authors.forename: Bin
authors.initials: B
authors.lastname: Yoo
authors.forename: Hee Bom
authors.initials: HB
authors.lastname: Moon
authors.forename: Chang-Keun
authors.initials: CK
authors.lastname: Lee
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D001022:Aortic Valve Insufficiency / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000473:pathology; D016706:Still's Disease, Adult-Onset / Q000150:complications*; D013997:Time Factors