Risk of birth defects among children conceived with assisted reproductive technology: providing an epidemiologic context to the data.
Studies of assisted reproductive technology (ART) and birth defects must be scrutinized and appropriately interpreted in the context of their limitations. The recent findings reported by Klemetti et al. are compelling, given the study's many strengths, and add to the accumulating evidence suggestive of an association between ART and birth defects.
Schieve
Laura A
LA
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. LSchieve@cdc.gov
Rasmussen
Sonja A
SA
Reefhuis
Jennita
J
D000015:Abnormalities, Multiple / Q000453:epidemiology / Q000209:etiology; D002648:Child; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D016017:Odds Ratio; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects* / Q000706:statistics & numerical data*; D012307:Risk Factors