title: Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men.
abstract: This investigation was designed to determine the effects of astaxanthin on markers of skeletal muscle injury. Twenty resistance trained men (mean +/- standard error of the mean : age , 25.1 +/- 1.6 y; height, 1.79 +/- 0.02 m; weight, 86.8 +/- 4.4 kg) were assigned to either a placebo (1732 mg safflower oil, n =10) or astaxanthin (BioAstin; 1732 mg safflower oil; haematococcus algae extract [contains 4 mg astaxanthin and 480 mg lutein]n = 10). Subjects consumed their assigned treatment for 3 wk prior to eccentric exercise (10 sets of 10 repetitions at 85% of one repetition maximum) and through 96 h post-exercise. Muscle soreness, creatine kinase (CK), and muscle performance was measured before and through 96 h post-exercise. A similar response was observed for both treatment groups for all dependent variables, indicating that in resistance trained men, astaxanthin supplementation does not favorably affect indirect markers of skeletal muscle injury following eccentric loading.
authors.affiliation: Dept. of Health and Sport Sciences the University of Memphis, Memphis, TN 38152, USA.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Bloomer
authors.forename: Andrew
authors.initials: A
authors.lastname: Fry
authors.forename: Brian
authors.initials: B
authors.lastname: Schilling
authors.forename: Loren
authors.initials: L
authors.lastname: Chiu
authors.forename: Naruhiro
authors.initials: N
authors.lastname: Hori
authors.forename: Lawrence
authors.initials: L
authors.lastname: Weiss
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology*; D000328:Adult; D003402:Creatine Kinase / Q000378:metabolism; D019587:Dietary Supplements; D004311:Double-Blind Method; D015444:Exercise; D006801:Humans; D008297:Male; D018763:Muscle Fatigue / Q000187:drug effects / Q000502:physiology; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000201:enzymology / Q000293:injuries*; D010147:Pain Measurement; D014891:Weight Lifting / Q000293:injuries / Q000502:physiology; D024341:Xanthophylls; D019207:beta Carotene / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D000276:Adjuvants, Immunologic; D024341:Xanthophylls; D019207:beta Carotene; C005948:astaxanthine; D003402:Creatine Kinase