Comparison of effects of uncomplicated canine babesiosis and canine normovolaemic anaemia on abdominal splanchnic Doppler characteristics--a preliminary investigation.
A preliminary study was conducted to compare uncomplicated canine babesiosis (CB) and experimentally induced normovolaemic anaemia (EA) using Doppler ultrasonography of abdominal splanchnic vessels. Fourteen dogs with uncomplicated CB were investigated together with 11 healthy Beagles during severe EA, moderate EA and the physiological state as a control group. Canine babesiosis was compared with severe EA, moderate EA and the physiological state using Doppler variables of the abdominal aorta, cranial mesenteric artery (CMA), coeliac, left renal and interlobar, and hilar splenic arteries, and the main portal vein. Patterns of haemodynamic changes during CB and EA were broadly similar and were characterised by elevations in velocities and reductions in resistance indices in all vessels except the renal arteries when compared with the physiological state. Aortic and CMA peak systolic velocities and CMA end diastolic and time-averaged mean velocities in CB were significantly lower (P < 0.023) than those in severe EA. Patterns of renal haemodynamic changes during CB and EA were similar. However, the renal patterns differed from those of aortic and gastrointestinal arteries, having elevations in vascular resistance indices, a reduction in end diastolic velocity and unchanged time-averaged mean velocity. The left renal artery resistive index in CB was significantly higher (P < 0.025) than those in EA and the physiological state. Renal interlobar artery resistive and pulsatility indices in CB were significantly higher (P < 0.016) than those of moderate EA and the physiological state. The similar haemodynamic patterns in CB and EA are attributable to anaemia, while significant differences may additionally be attributed to pathophysiological factors peculiar to CB.
Koma
L M
LM
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa. lee.koma@vetmed.mak.ac.ug
Kirberger
R M
RM
Leisewitz
A L
AL
Jacobson
L S
LS
Becker
P J
PJ
Bland van den Berg
P
P
D000740:Anemia / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000662:veterinary*; D000818:Animals; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging / Q000502:physiology; D001404:Babesiosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000662:veterinary*; D001783:Blood Flow Velocity / Q000662:veterinary; D002445:Celiac Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D008297:Male; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging / Q000502:physiology; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000502:physiology; D013152:Splanchnic Circulation / Q000502:physiology*; D018608:Ultrasonography, Doppler / Q000379:methods / Q000662:veterinary*