title: Managing and mining protein crystallization data.
abstract: The crystallization of macromolecules remains a major bottleneck in structural biology. The routine screening of more than one thousand crystallization conditions and subsequent optimization by fine screening presents a challenge to conventional laboratory notebook keeping. In addition, the development of high-throughput robotic crystallization and imaging systems presents a pressing need for low-cost laboratory information management system (LIMS). Here we describe CLIMS2, a crystallization LIMS that features a simple, user-friendly graphical interface, allowing the storage, management, retrieval and mining of crystallization data. The CLIMS2 executable and documentation is freely available at http://clims.med.monash.edu.au.
authors.affiliation: Victorian Bioinformatics Consortium, Monash University, Clayton, Victoria, Australia.
authors.forename: Abdullah A
authors.initials: AA
authors.lastname: Amin
authors.forename: Noel G
authors.initials: NG
authors.lastname: Faux
authors.forename: Gustavo
authors.initials: G
authors.lastname: Fenalti
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Williams
authors.forename: Adam
authors.initials: A
authors.lastname: Bernadou
authors.forename: Ben
authors.initials: B
authors.lastname: Daglish
authors.forename: Karen
authors.initials: K
authors.lastname: Keefe
authors.forename: Shayne
authors.initials: S
authors.lastname: Middleton
authors.forename: Joseph
authors.initials: J
authors.lastname: Rae
authors.forename: Kosmas
authors.initials: K
authors.lastname: Tetis
authors.forename: Ruby H P
authors.initials: RH
authors.lastname: Law
authors.forename: Kate F
authors.initials: KF
authors.lastname: Fulton
authors.forename: Jamie
authors.initials: J
authors.lastname: Rossjohn
authors.forename: James C
authors.initials: JC
authors.lastname: Whisstock
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Buckle
mesh_terms: D003196:Computer Graphics; D003460:Crystallization; D030562:Databases, Protein; D007256:Information Systems; D046911:Macromolecular Substances / Q000737:chemistry; D011506:Proteins / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D046911:Macromolecular Substances; D011506:Proteins