Ovarian cortical transplantation may be an alternative to hormone therapy in patients with early climacterium.
OBJECTIVE
To discuss the 18-month follow-up results of fresh ovarian cortical tissue transplant.


METHODS
Case study.


METHODS
Academic medical center.


METHODS
A 46-year-old patient who was operated on for uterine fibroids, and who then received an ovarian tissue transplant in July 2003.


METHODS
Serum hormone levels were measured at 3-month intervals.


METHODS
Follicular development evident by ultrasound examination; serum hormone levels (FSH, LH, E2).


RESULTS
Preoperative and 3rd-, 6th-, 9th-, 12th-, 15th-, and 18th-month hormone levels were, respectively, as follows: FSH: 9.06, 79.5, 13.7, 16.66, 51.91, 44.37, and 24.17 mIU/mL; LH: 5.91, 33.92, 8.78, 21.83, 38.31, 40.85, and 22.4 mIU/mL; E2: 166, 46, 48, 117, 31, 14.4, and 137.7 pg/mL. Folliculogenesis was confirmed by ultrasonography at the 6th, 9th, and 18th months during the follow-up period.


CONCLUSIONS
Fresh ovarian autotransplantation may be a logical alternative for hormonal support for a specific patient group.
Kiran
Gurkan
G
Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey. gurkankiran@ksu.edu.tr
Kiran
Hakan
H
Coban
Y Kenan
YK
Guven
Alanur M
AM
D002979:Climacteric / Q000187:drug effects* / Q000502:physiology; D015914:Estrogen Replacement Therapy / Q000379:methods; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000601:surgery / Q000628:therapy; D008875:Middle Aged; D010053:Ovary / Q000637:transplantation*; D016378:Tissue Transplantation / Q000379:methods