Shigella and Salmonella: death as a means of survival.
Shigella and Salmonella kill host cells and trigger inflammatory responses by mechanisms that are not fully understood. The goal of this review is to reevaluate key observations reported over the past 15 years and, whenever possible, to provide a chronological perspective as to how our understanding of the pathways by which Shigella and Salmonella kill host cells has evolved.
Haimovich
Beatrice
B
Department of Surgery and the Cancer Institute of New Jersey, RWJMS-UMDNJ, New Brunswick, NJ 08903, USA. haimovic@umdnj.edu
Venkatesan
Malabi M
MM
D000818:Animals; D017209:Apoptosis; D002460:Cell Line; D006801:Humans; D051379:Mice; D009336:Necrosis; D010586:Phagocytes / Q000382:microbiology* / Q000502:physiology; D012475:Salmonella / Q000254:growth & development* / Q000472:pathogenicity*; D012760:Shigella / Q000254:growth & development* / Q000472:pathogenicity*; D020298:U937 Cells / Q000382:microbiology; D014774:Virulence