Fungal CO2 sensing: a breath of fresh air.
Carbon dioxide levels are used by two fungal pathogens as a key signal to choose between the expression of environmental or virulence traits. Studies now reveal that the atypical fungal adenylyl cyclases are implicated in this decision.
Mitchell
Aaron P
AP
Department of Microbiology, Columbia University, New York, NY 10032, USA. apm4@columbia.edu
D000262:Adenylyl Cyclases / Q000235:genetics / Q000378:metabolism*; D001639:Bicarbonates / Q000378:metabolism; D002176:Candida albicans / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism*; D024402:Carbonic Anhydrase II / Q000235:genetics / Q000378:metabolism; D003455:Cryptococcus neoformans / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity*; D015966:Gene Expression Regulation, Fungal; D012098:Reproduction / Q000502:physiology; D013172:Spores, Fungal / Q000472:pathogenicity / Q000502:physiology*; D014774:Virulence
D001639:Bicarbonates; D002245:Carbon Dioxide; D024402:Carbonic Anhydrase II; D000262:Adenylyl Cyclases