Cortical activity of children with dyslexia during natural speech processing: evidence of auditory processing deficiency.
Children with dyslexia have difficulties with phonological processing. It is assumed that deficits in auditory temporal processing underlie the phonological difficulties of dyslectic subjects (i.e. the processing of rapid acoustic changes that occur in speech). In this study we assessed behavioral and electrophysiological evoked brain responses of dyslectic and skilled reading children while performing a set of hierarchically structured auditory tasks. Stimuli consisted of auditory natural unmodified speech that was controlled for the parameter of changing rate of main acoustic cues: vowels (slowly changing speech cues: /i/ versus /u/) and consonant-vowel (CV) syllables (rapidly changing speech cues: /da/ versus /ga/). Brain auditory processing differed significantly between groups: reaction time of dyslectic readers was prolonged in identifying speech stimuli and increased with increased phonological demand. Latencies of auditory evoked responses (auditory event related potentials [AERPs]) recorded during syllable identification of the dyslectic group were prolonged relative to those of skilled readers. Moreover, N1 amplitudes during vowel processing were larger for the dyslectic children and P3 amplitudes during CV processing were smaller for the dyslectic children. From the results of this study it is evident that the latency and amplitude of AERPs are sensitive measures of the complexity of phonological processing in skilled and dyslectic readers. These results may be signs of deficient auditory processing of natural speech under normal listening conditions as a contributing factor to reading difficulties in dyslexia. Detecting a dysfunction in the central auditory processing pathway might lead to early detection of children who may benefit from phonetic-acoustic training methods.
Putter-Katz
Hanna
H
Department of Communication Disorders, Tel Aviv University, Tel Aviv, Israel. hanna.putterkatz@sheba.health.gov.il
Kishon-Rabin
Liat
L
Sachartov
Emma
E
Shabtai
Esther L
EL
Sadeh
Michelle
M
Weiz
Raphael
R
Gadoth
Natan
N
Pratt
Hillel
H
D000161:Acoustic Stimulation; D000293:Adolescent; D001306:Auditory Pathways / Q000502:physiology; D002648:Child; D004410:Dyslexia / Q000209:etiology / Q000503:physiopathology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D006801:Humans; D008297:Male; D010700:Phonetics; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D011932:Reading; D013067:Speech Perception / Q000502:physiology*