title: Bioactive constituents from roots of Bursera tonkinensis.
abstract: Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Si Ayutthaya Road, Ratchathewi District, Bangkok 10400, Thailand.
authors.forename: Aranya
authors.initials: A
authors.lastname: Jutiviboonsuk
authors.forename: Hongjie
authors.initials: H
authors.lastname: Zhang
authors.forename: Ghee Teng
authors.initials: GT
authors.lastname: Tan
authors.forename: Cuiying
authors.initials: C
authors.lastname: Ma
authors.forename: Nguyen
authors.initials: N
authors.lastname: Van Hung
authors.forename: Nguyen
authors.initials: N
authors.lastname: Manh Cuong
authors.forename: Nuntavan
authors.initials: N
authors.lastname: Bunyapraphatsara
authors.forename: D Doel
authors.initials: DD
authors.lastname: Soejarto
authors.forename: Harry H S
authors.initials: HH
authors.lastname: Fong
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology*; D031233:Bursera / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D011034:Podophyllotoxin / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: C508085:4'-demethyldesoxypodophyllotoxin; D000972:Antineoplastic Agents, Phytogenic; D017705:Lignans; D011034:Podophyllotoxin