Nasal Wegener's and skin sarcoid--a rare combination of two granulomatous diseases.
Wegener's granulomatosis (WG) and sarcoidosis are two distinct granulomatous diseases characterized by multisystem involvement. We report a patient who initially presented with symptoms of limited WG predominantly affecting the nose, followed by a facial rash, which was histologically proven to be due to sarcoidosis. The sequential development of these two diseases in one patient is very rare, and to our knowledge, only one such case has been reported in the last 50 years (Am J Kidney Dis 28:893-898, 1996).
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Department of Rheumatology, Harold Wood Hospital, Barking, Havering and Redbridge Hospitals NHS Trust, Romford, RM3 OBE, Essex, UK. Kuntal.Chakravarty@bhrhospitals.nhs.uk
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Chopra
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Chopra
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Chakravarty
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D000328:Adult; D005145:Face; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D009297:Nasal Mucosa / Q000473:pathology; D009668:Nose Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D019233:Retreatment; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
D005938:Glucocorticoids; D011239:Prednisolone; D008727:Methotrexate