Ultrastructural analysis of secretory granules of myocardial capillary endothelium in cardiosurgical stress.
In patients with chronic myocardial tissue hypoxia irrespective of the disease (Fallot's tetralogy, coronary disease) factors of cardiosurgical stress initiate a drop of secretory production in coronary capillary endothelium and obstruction of the intravascular space by blood cells. In children the peak of exocytosis of secretory granules coincides with the period of aortic occlusion, while in adults it is attained at the stage of reperfusion.
Kazanskaya
G M
GM
E. N. Meshalkin Novosibirsk Institute of Circulatory Diseases, Ministry of Health of Siberian Region of Russian Federation, Novosibirsk.
Volkov
A M
AM
Nepomnyashchikh
L M
LM
Malinovskaya
Y V
YV
Chernyavskii
A M
AM
Gorbatykh
Y N
YN
D'yakonitsa
T M
TM
D002196:Capillaries / Q000648:ultrastructure; D002675:Child, Preschool; D001026:Coronary Artery Bypass; D004730:Endothelium, Vascular / Q000473:pathology* / Q000648:ultrastructure; D005089:Exocytosis; D006801:Humans; D000860:Hypoxia; D007223:Infant; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology* / Q000648:ultrastructure*; D015427:Reperfusion Injury; D022142:Secretory Vesicles / Q000648:ultrastructure; D013771:Tetralogy of Fallot / Q000601:surgery; D013903:Thoracic Surgery