Recent progress in the battle between oncolytic viruses and tumours.
In the past 5 years, the field of oncolytic virus research has matured significantly and is moving past the stage of being a laboratory novelty into a new era of preclinical and clinical trials. What have recent anticancer trials of oncolytic viruses taught us about this exciting new line of therapeutics?
Parato
Kelley A
KA
Centre for Cancer Therapeutics, Ottawa Health Research Institute, 503 Smyth Road, Ottawa, Ontario, Canada K1H 8L6.
Senger
Donna
D
Forsyth
Peter A J
PA
Bell
John C
JC
D000818:Animals; D002986:Clinical Trials as Topic; D014644:Genetic Variation; D006801:Humans; D015810:Linkage Disequilibrium; D009369:Neoplasms / Q000628:therapy* / Q000821:virology; D050130:Oncolytic Virotherapy; D050504:Oncolytic Viruses / Q000502:physiology*; D012307:Risk Factors