Oral lichenoid contact reactions may occasionally transform into malignancy.
The purpose was to identify cases of squamous cell carcinoma (SCC) of the tongue, in which a biopsy taken at the site preceding the cancer could be verified to show a lichenoid contact type of reaction (LCR). We retrieved all 724 SCC of the tongue from the Swedish Cancer Registry in the period 1995-2000. These cases were cross-searched with our own oral biopsy data files from 1988 to 1994, in order to identify biopsies with LCR-type lesions preceding the cancer. We found four verified and some additional tentative cases. The study demonstrated that there is a low incidence of malignant transformation in LCR-type oral lesions, not much different from what has been previously reported in oral lichen planus.
Larsson
A
A
Department of Oral Pathology, University of Malmö, Malmö, Sweden. ake.larsson@od.mah.se
Warfvinge
G
G
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D005260:Female; D006801:Humans; D017512:Lichenoid Eruptions / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D014062:Tongue Neoplasms / Q000209:etiology / Q000473:pathology*