500-1000 Hz responses in the somatosensory system: approaching generators and function.
Spontaneous and stimulus-induced oscillatory EEG activities range over a wide scope of frequencies from 1 Hz to 1 kHz. In the ultrafast domain, trains of 5-10 micropotentials are superimposed to primary thalamic and cortical components in somtosensory evoked potentials (SEP) as brief bursts of 1000 Hz and 600 Hz, respectively. Over the last years, hypotheses on generators and functions of this frequency-edge of population activity have been elaborated in numerous studies. Here, the relevant findings and ideas were surveyed from the body of literature. Special emphasis was paid to the anatomical and cellular origin of burst SEP, their assumed impact on somatosensory coding and perspectives for scientific as well as clinical applications.
Klostermann
Fabian
F
Charité-Universitätsmedizin Berlin, CBF, Dept. ol Neurology, Hindenburgdamm 30, 12200 Berlin, Germany. fabian.klostermann@charite.de
D000200:Action Potentials / Q000502:physiology; D001683:Biological Clocks / Q000502:physiology*; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D004569:Electroencephalography / Q000379:methods*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D009474:Neurons / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*