title: Interosseous ligament tears of the wrist: comparison of multi-detector row CT arthrography and MR imaging.
abstract: OBJECTIVE
  To compare the accuracy of multi-detector row computed tomographic (CT) arthrography and magnetic resonance (MR) imaging in depicting tears of dorsal, central, and palmar segments of scapholunate (SL) and lunotriquetral (LT) ligaments in cadavers.
  
  
  METHODS
  Cadaver wrists were obtained and used according to institutional guidelines and with informed consent of donors prior to death. Nine cadaver wrists of eight subjects were evaluated. MR images were obtained with a 1.5-T MR unit. Imaging protocol included intermediate-weighted coronal and transverse fast spin-echo and coronal three-dimensional gradient-echo sequences. Multi-detector row CT arthrography was performed after tricompartmental injection of 3-6 mL of contrast material with a concentration of 160 mg per milliliter of iodine. Palmar, dorsal, and central segments of both ligaments were analyzed on transverse and coronal MR images and multiplanar multi-detector row CT reconstructions by two musculoskeletal radiologists working independently. Open inspection of the wrists was the reference standard. Sensitivity, specificity, accuracy, and positive and negative predictive values were calculated from the imaging and gross pathologic readings. Statistical significance was calculated with the McNemar test. Weighted kappa values for interobserver agreement were calculated for both imaging modalities.
  
  
  RESULTS
  All ligament segments could be visualized in all cases with both imaging modalities. CT arthrography was more sensitive (100%) than MR imaging (60%) in detection of palmar segment tears (P = .62); specificity of both imaging modalities was 77%. Sensitivity (CT arthrography, 86%; MR imaging, 79%) and specificity (CT arthrography, 50%; MR imaging, 25%) for detection of the central segment tears were determined. Dorsal segment tears were detected only with CT arthrography, while all tears were missed with MR imaging (P = .02). Interobserver agreement was better for multi-detector row CT arthrography (kappa = 0.37-0.78) than for MR imaging (kappa = -0.33 to -0.10).
  
  
  CONCLUSIONS
  Performance in depiction of palmar and central segment tears of SL and LT ligaments is almost equal for multi-detector row CT arthrography and MR imaging, with much higher interobserver reliability for CT arthrography. CT arthrography is significantly superior to MR imaging in the detection of dorsal segment tears of SL and LT ligaments.
authors.affiliation: Department of Radiology, Balgrist University Hospital, Forchstrasse 340, CH-8008 Zurich, Switzerland. marius.schmid@balgrist.ch
authors.forename: Marius R
authors.initials: MR
authors.lastname: Schmid
authors.forename: Thomas
authors.initials: T
authors.lastname: Schertler
authors.forename: Christian W
authors.initials: CW
authors.lastname: Pfirrmann
authors.forename: Nadja
authors.initials: N
authors.lastname: Saupe
authors.forename: Mirjana
authors.initials: M
authors.lastname: Manestar
authors.forename: Simon
authors.initials: S
authors.lastname: Wildermuth
authors.forename: Dominik
authors.initials: D
authors.lastname: Weishaupt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001175:Arthrography / Q000379:methods*; D002102:Cadaver; D003287:Contrast Media; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008023:Ligaments, Articular / Q000000981:diagnostic imaging / Q000293:injuries*; D008279:Magnetic Resonance Imaging; D008297:Male; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014954:Wrist Injuries / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media