Antifungal activity of Boerhavia diffusa against some dermatophytic species of Microsporum.
Various extracts petroleum ether, chloroform, ethyl acetate and ethyl alcohol) of aerial and root parts of Boerhavia diffusa was sereened for Antitungal activity (Inhibition in sporulation) against dermatophytic fungi Microsporum gypseum, M. fulvum and M. canis by using broth dilution method. Extracts of aerial part not show any noticeable antifungal activity. Ethyl acetate extract of root part of the plant was found to be most effective of against target fungal species. The maximum inhibition of mycelial growth was observed for M. gypseum (78.83%) followed by M. fulvum (62.33%) and M. canis (42.30%) of ethyl acetate in the test concentration of 1000 microg/ml 24 hours of incubation. The sporulation of target fungal species decreases with increasing supplementation of phytoextract, confirms the presence of some antifungal phytochemical moiety in roots of the plant.
Agrawal
Anurag
A
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Dayalbagh, Agra - 282001 India.
Srivastava
Shalini
S
Srivastava
M M
MM
D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects*; D007194:India; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects*; D039281:Nyctaginaceae / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
D000935:Antifungal Agents; D010936:Plant Extracts