title: A new guaiane diterpenoid from Euphorbia wallichii.
abstract: A new guaiane-type diterpenoid, (1alpha,5beta,7alpha)-3,10(18),11-dictytriene-19-acid, was obtained from the roots of Euphorbia wallichii. This is the first isolation of guaiane diterpene from this genus of Euphorbia. The structure was elucidated by spectral methods. And the compound was tested for the cytotoxicities on the cancer cell line P-388 and A-549 in vitro.
authors.affiliation: North West Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, P.R. China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Zhang
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Jianwei
authors.initials: J
authors.lastname: Sheng
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Luo
mesh_terms: D045744:Cell Line, Tumor; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D028481:Euphorbia / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004224:Diterpenes