Description of a new HLA-DRB1*1104, DRB1*110403.
We report here the exon 2 sequence of the novel HLA-DRB1*110403 which differs from DRB1*110401 by a single synonymous nucleotide substitution at codon 78, where TAC is substituted by TAT. The variant originally identified in a Caucasoid individual was confirmed by cloning and sequencing.
Longhi
E
E
Dipartimento Trasfusionale e di Riferimento per i Trapianti di Organi e Tessuti - Unità Operativa per il Prelievo e la Conservazione di Organi e Tessuti, Ospedale Maggiore Policlinico, Milan, Italy.
Frison
S
S
Andreini
E
E
Favoino
B
B
Poli
F
F
Scalamogna
M
M
D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D005838:Genotype; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010375:Pedigree; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational; D012689:Sequence Homology, Nucleic Acid; D044465:White People
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains