title: Life-threatening meningitis resulting from transrectal prostate biopsy.
abstract: After antibiotic prophylaxis with metronidazole and levofloxacin, a transrectal sextant biopsy was performed under the guide of transrectal ultrasonography (TRUS) for a 75-year-old suspicious patient with prostate adenocarcinoma. Although antibiotics were also given after this procedure, the patient still developed fever, anxious, agrypnia and headache. Blood cultures remained negative. Lumbar puncture was performed and was consistent with Escherichia coli bacterial meningitis.
authors.affiliation: Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China. shenzhj@mail.hz.zj.cn
authors.forename: Zhou-Jun
authors.initials: ZJ
authors.lastname: Shen
authors.forename: Shan-Wen
authors.initials: SW
authors.lastname: Chen
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Xie-Lai
authors.initials: XL
authors.lastname: Zhou
authors.forename: Ju-Ping
authors.initials: JP
authors.lastname: Zhao
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage; D001706:Biopsy / Q000009:adverse effects*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008581:Meningitis / Q000209:etiology* / Q000382:microbiology / Q000517:prevention & control; D008795:Metronidazole / Q000008:administration & dosage; D015242:Ofloxacin / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000473:pathology*; D036761:Ultrasound, High-Intensity Focused, Transrectal
chemical_list: D000890:Anti-Infective Agents; D000892:Anti-Infective Agents, Urinary; D008795:Metronidazole; D064704:Levofloxacin; D015242:Ofloxacin