A phenolic glucoside isolated from Prunus serrulata var. spontanea and its peroxynitrite scavenging activity.
A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-omicron-glucoside (2), 1beta, 2alpha, 3alpha, 24-tetrahydroxy-urs-12-en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-omicron-beta-(6'-benzoyl)-glucopyranosyl omicron-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO scavenging activity, whereas compound 3 was determined to be virtually inactive.
Jung
Hyun Ah
HA
Faculty of Food Science and Biotechnology, Pukyong National University, Busan, Korea.
Chung
Hae Young
HY
Kang
Sam Sik
SS
Hyun
Sook Kyung
SK
Kang
Hye Sook
HS
Choi
Jae Sue
JS
D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction / Q000187:drug effects; D030421:Peroxynitrous Acid / Q000737:chemistry*; D019800:Phenol / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D027861:Prunus / Q000737:chemistry*
D016166:Free Radical Scavengers; D005960:Glucosides; D010936:Plant Extracts; D030421:Peroxynitrous Acid; D019800:Phenol