title: Recurrent bacterial vaginosis: the use of maintenance acidic vaginal gel following treatment.
abstract: Bacterial vaginosis (BV) frequently recurs after treatment. One option in the management of recurrences is to keep the vaginal pH at 4.5 or less, in order to prevent overgrowth of bacteria, until the normal lactobacilli are re-established. We report the outcome of using maintenance acetic acid vaginal gel, after treatment of BV, in a sample of 49 women with frequent recurrences. Half of the women had no further recurrences, and in those who did there was a significant increase in time to first recurrence (4.8 months) after commencing the gel compared with the previous recurrence (2.1 months). Prior to using acidic gel, the mean recurrence rate in 49 women was 4.4 per woman/year, and this was reduced to 0.6 recurrences per woman/year. As there are few effective therapies for women with recurrent BV, we feel this offers an option that can currently be used in clinical practice.
authors.affiliation: Department of Genitourinary Medicine, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK. janet_d.wilson.nhs.uk
authors.forename: J D
authors.initials: JD
authors.lastname: Wilson
authors.forename: S M
authors.initials: SM
authors.lastname: Shann
authors.forename: S K
authors.initials: SK
authors.lastname: Brady
authors.forename: A G
authors.initials: AG
authors.lastname: Mammen-Tobin
authors.forename: A L
authors.initials: AL
authors.lastname: Evans
authors.forename: R A
authors.initials: RA
authors.lastname: Lee
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome; D014621:Vagina / Q000737:chemistry; D014622:Vaginal Creams, Foams, and Jellies / Q000627:therapeutic use*; D016585:Vaginosis, Bacterial / Q000188:drug therapy* / Q000517:prevention & control*
chemical_list: D014622:Vaginal Creams, Foams, and Jellies