title: Role of cultivation media in the development of yeast strains for large scale industrial use.
abstract: The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by Saccharomyces cerevisiae are used to illustrate the influence of media composition at different stages of strain construction and strain development. The effects of complex, defined and industrial media are compared. Auxotrophic strains and strain stability are discussed. Media for heterologous protein production and for bulk bio-commodity production are summarized.
authors.affiliation: Applied Microbiology, LTH/Lund University, P O Box 124, SE-221 00 Lund, Sweden. barbel.hahn-hagerdal@tmb.lth.se
authors.forename: Bärbel
authors.initials: B
authors.lastname: Hahn-Hägerdal
authors.forename: Kaisa
authors.initials: K
authors.lastname: Karhumaa
authors.forename: Christer U
authors.initials: CU
authors.lastname: Larsson
authors.forename: Marie
authors.initials: M
authors.lastname: Gorwa-Grauslund
authors.forename: Johann
authors.initials: J
authors.lastname: Görgens
authors.forename: Willem H
authors.initials: WH
authors.lastname: van Zyl