title: Comparison of optical coherence tomography models OCT1 and Stratus OCT for macular retinal thickness measurement.
abstract: OBJECTIVE
  To compare the values measured for retinal macular thickness with the first and last generations of the optical coherence tomograph (OCT1 and Stratus OCT, Zeiss, Humphrey Division).
  
  
  METHODS
  This was a cohort study. 59 eyes were examined: 17 had a normal macula and 42 had a diabetic macular oedema. In each eye, mean retinal thickness (RT) was measured automatically in the nine macular Early Treatment Diabetic Retinopathy Study areas and at the foveal centre, using OCT1 and Stratus OCT. The paired mean RT values for each area and the type and proportion of artefacts were compared.
  
  
  RESULTS
  Of the 590 automatic measurements, 505 had no artefact, either with OCT1 or Stratus OCT. The mean difference between the OCT1 and Stratus OCT measurements was 25 (SD 26.2) microm (p<0.0001). With Stratus OCT, RT values were significantly higher, by 8.1% (7.8%), than with OCT1. Artefacts were only observed in cases of diabetic macular oedema and were significantly more frequent with OCT1 than Stratus OCT (10.5% versus 4.4, p<0.0001).
  
  
  CONCLUSIONS
  The macular retinal thickness values measured with Stratus OCT were significantly higher than those measured with OCT1. Stratus OCT has the advantage of producing fewer artefacts than OCT1 in pathological cases.
authors.affiliation: Service d'Ophtalmologie, Hôpital Lariboisière 2, rue Ambroise Paré, 75475 Paris Cedex 10, France.
authors.forename: V
authors.initials: V
authors.lastname: Pierre-Kahn
authors.forename: R
authors.initials: R
authors.lastname: Tadayoni
authors.forename: B
authors.initials: B
authors.lastname: Haouchine
authors.forename: P
authors.initials: P
authors.lastname: Massin
authors.forename: A
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000328:Adult; D016477:Artifacts; D015331:Cohort Studies; D003930:Diabetic Retinopathy / Q000175:diagnosis*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008269:Macular Edema / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000295:instrumentation*