title: Genitourinary manifestations of Klippel-Trenaunay syndrome: report of two cases managed with systemic alpha-interferon.
abstract: We present our experience of two cases with genitourinary manifestations of Klippel-Trenaunay syndrome. A MEDLINE search for the period 2001-2004 was done using the keywords "Klippel-Trenaunay syndrome", "vascular malformation" and "genitourinary". Only three cases with genitourinary manifestations of this syndrome were reported during this period. Genitourinary problems are rare in Klippel-Trenaunay syndrome; however, their management may be a challenge for the urologist. In one of our patients who failed to respond to endoscopic laser coagulation and partial cystectomy we used systemic alpha-interferon, with a good short-term response.
authors.affiliation: Department of Urology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. ahmedirfan2000@hotmail.com
authors.forename: Irfan
authors.initials: I
authors.lastname: Ahmed
authors.forename: Muhammad
authors.initials: M
authors.lastname: Aslam
authors.forename: Ali
authors.initials: A
authors.lastname: Bin Mahfooz
authors.forename: Kamal
authors.initials: K
authors.lastname: Hanash
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D052776:Female Urogenital Diseases / Q000175:diagnosis / Q000188:drug therapy*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D016898:Interferon-alpha / Q000627:therapeutic use*; D007715:Klippel-Trenaunay-Weber Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D052801:Male Urogenital Diseases; D014057:Tomography, X-Ray Computed
chemical_list: D020533:Angiogenesis Inhibitors; D016898:Interferon-alpha