The association between nuchal nevus flammeus and alopecia areata: a case-control study.
BACKGROUND
The association of alopecia areata (AA) with nuchal nevus flammeus (NNF) has been demonstrated by previous studies.


OBJECTIVE
The aim of this study was to investigate whether AA is associated with NNF.


METHODS
199 AA patients and 215 controls without AA were examined for the presence of NNF.


RESULTS
35 patients (17.6%) in the AA group had NNF. In the control group, 20 patients (9.3%) had NNF (odds ratio = 2.08, 95% confidence interval 1.43-2.73; p = 0.013). A statistically significant association was found between the presence of NNF and duration of the AA (p < 0.001). The presence of NNF was associated with severity of AA (p < 0.001).


CONCLUSIONS
The results of our study suggest a link between NNF and AA especially in severer and more chronic forms.
Akhyani
Maryam
M
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Farnaghi
Farshad
F
Seirafi
Hassan
H
Nazari
Rahman
R
Mansoori
Parisa
P
Taheri
Arash
A
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000506:Alopecia Areata / Q000145:classification / Q000150:complications* / Q000235:genetics; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008875:Middle Aged; D009333:Neck / Q000473:pathology*; D019339:Port-Wine Stain / Q000150:complications*