Vaccines for sexually transmitted infections.
STIs are responsible for significant human suffering and carry significant economic costs. Strategies to control STIs, such as screening programs and condoms, have had limited success. Vaccines offer an additional method that is not coitally related and does not depend on consistent use. The HPV vaccine confers protection against the most common types causing cervical dysplasia. Mathematical modeling suggests that the HSV vaccine, given universally to all young women, should reduce genital and neonatal herpes in the population at large. Much work remains on vaccines for chlamydia and gonorrhea, but they offer the hope of preventing pelvic inflammatory disease and its sequelae. As these vaccines become licensed, their successful implementation will require the support of professional organizations, families, and providers.
Rupp
Richard E
RE
Division of Adolescent and Behavioral Health, Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX, USA. rrupp@utmb.edu
Stanberry
Lawrence R
LR
Rosenthal
Susan L
SL
D000293:Adolescent; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D002690:Chlamydia Infections / Q000517:prevention & control; D002692:Chlamydia trachomatis / Q000276:immunology; D006801:Humans; D027383:Papillomaviridae / Q000276:immunology; D030361:Papillomavirus Infections / Q000517:prevention & control; D012749:Sexually Transmitted Diseases / Q000517:prevention & control*; D018139:Simplexvirus / Q000276:immunology; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
D001428:Bacterial Vaccines; D014765:Viral Vaccines