Rare thoracic mass lesion--myofibrobastoma.
Mesenchymal soft tissue masses are uncommon tumours of the chest. Myofibroblastoma is a recently described entity consisting of cells with origin from the myoepethelial cell, mostly seen as benign well-circumscribed neoplasms of the breast tissue. Though usually classified as a benign lesion, rarely it can be multifocal and prone to recurrence. We describe below the case of a 26-year-old female who presented with exertional dyspnoea and evidence of a massive mass lesion in the left hemithorax causing mediastinal displacement to the opposite side. On histological and immunophenotypic analysis, a diagnosis of the very rare thoracic myofibroblastoma was made. The incidence, salient features, pathological differential diagnoses and treatment are reviewed.
Sahni
Vaibhav
V
Department of Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, G. B. Pant Hospital and Guru Nanak Eye Hospital, New Delhi-110 002, India. vaibhavsahni@hotmail.com
Sunandan
Sikdar
S
Agarwal
Satish K
SK
Singh
Narinder P
NP
Ganguli
Anirban
A
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*