A stochastic model of elbow flexion strength for subjects with and without long head biceps tear.
The classical approach of musculoskeletal modeling is to predict muscle forces and joint torques with a deterministic model constructed from parameters of an average subject. However, this type of model does not perform well for outliers, and does not model the effects of parameter variability. In this study, a Monte-Carlo model was used to stochastically simulate the effects of variability in musculoskeletal parameters on elbow flexion strength in healthy normals, and in subjects with long head biceps (LHB) rupture. The goal was to determine if variability in elbow flexion strength could be quantifiably explained with variability in musculoskeletal parameters. Parameter distributions were constructed from data in the literature. Parameters were sampled from these distributions and used to predict muscle forces and joint torques. The median and distribution of measured joint torque was predicted with small errors (< 5%). Muscle forces for both cases were predicted and compared. In order to predict measured torques for the case of LHB rupture, the median force and mean cross-sectional area in the remaining elbow flexor muscles is greater than in healthy normals. The probabilities that muscle forces for the Tear case exceed median muscle forces for the No-Tear case are 0.98, 0.99 and 0.79 for SH Biceps, brachialis and brachioradialis, respectively. Differences in variability of measured torques for the two cases are explained by differences in parameter variability.
Langenderfer
Joseph E
JE
University of Michigan, MedSport and Orthopaedic Research Laboratories, Ann Arbor, MI, USA.
Hughes
Richard E
RE
Carpenter
James E
JE
D003198:Computer Simulation; D004551:Elbow Joint / Q000503:physiopathology*; D006801:Humans; D007537:Isometric Contraction; D008954:Models, Biological; D015233:Models, Statistical; D018482:Muscle, Skeletal / Q000293:injuries* / Q000503:physiopathology*; D010807:Physical Endurance; D012421:Rupture; D013269:Stochastic Processes; D013314:Stress, Mechanical; D019415:Torque