[Variants of heart remodeling in essential hypertension: prevalence and determinants].
OBJECTIVE
To study myocardial remodeling (MR) in hypertensive patients with normal and excessive body mass, to analyse MR features depending on clinical and hemodynamic parameters.


METHODS
Structural-functional conditions of the myocardium were studied with echocardiography, and determination of left ventricular remodeling (LVR) type was made in 734 untreated hypertensive patients aged 19-76 years.


RESULTS
Patients with essential hypertension (EH) stage I had mostly excentric left ventricular hypertrophy (LVH). The number of patients with concentric LVH increases with age, disease severity. This type of LVH occurs more frequently in males than in females. In females, LVH severity depends, primarily, on the degree of obesity. If EH combines with obesity, structural alterations of the myocardium are more prominent than in isolated pathology. In android obesity, LVH is more frequent.


CONCLUSIONS
In EH, structural alterations of the heart and a LVR variant are determined, besides arterial pressure, by such factors as age and gender, duration of EH, obesity, its degree and kind.
Konradi
A O
AO
Rudomanov
O G
OG
Zakharov
D V
DV
Vakhrameeva
N V
NV
Krutikov
A N
AN
Iakovleva
O I
OI
Shliakhto
E V
EV
D000328:Adult; D000367:Age Factors; D000368:Aged; D001835:Body Weight; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D009765:Obesity / Q000150:complications* / Q000473:pathology; D015995:Prevalence; D012737:Sex Factors; D020257:Ventricular Remodeling