Making a monkey out of HIV. More is becoming clear about a novel host factor that appears central to governing the species-specificity of retroviruses like HIV and could be a future antiviral target.
Cohen
Philip
P
D000071478:APOBEC Deaminases; D000818:Animals; D000090103:Antiviral Restriction Factors; D002352:Carrier Proteins / Q000235:genetics; D003564:Cytidine Deaminase; D043525:Cytosine Deaminase / Q000235:genetics; D015658:HIV Infections / Q000276:immunology*; D000882:Haplorhini / Q000235:genetics; D006801:Humans; D007113:Immunity, Innate; D012190:Retroviridae; D013045:Species Specificity; D000070584:Tripartite Motif Proteins; D044767:Ubiquitin-Protein Ligases
D000090103:Antiviral Restriction Factors; D002352:Carrier Proteins; D000070584:Tripartite Motif Proteins; C477346:TRIM5 protein, human; D044767:Ubiquitin-Protein Ligases; D043525:Cytosine Deaminase; D000071478:APOBEC Deaminases; C502889:APOBEC3 proteins, human; D003564:Cytidine Deaminase