Intestinal oxalate absorption in patients with continent urinary diversion.
The objective of the study is to evaluate the post-operative effect of an orthotopic ileal neobladder or a Mainz pouch I bladder replacement on the extent of intestinal oxalate absorption. Gastrointestinal oxalate absorption was measured in six patients with an orthotopic ileal neobladder and in six patients with a Mainz pouch I bladder replacement. The function test applied was the [13C2]oxalate absorption test. With a range of 5.1-12.4%, the oxalate absorption of these patients was well within the reference range for healthy volunteers. The results from our small study indicate that such continent urinary diversions present no hazard for oxalate hyperabsorption and subsequent calcium oxalate urolithiasis.
von Unruh
Gerd E
GE
Department of Internal Medicine I, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. gerd.von_unruh@ukb.uni-bonn.de
Ernst
Friederike B
FB
Schmidt
Matthias E
ME
Steiner
Gabriel
G
Hesse
Albrecht
A
Müller
Stefan C
SC
D000368:Aged; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D010070:Oxalates / Q000378:metabolism*; D010865:Pilot Projects; D016476:Urinary Reservoirs, Continent
D010070:Oxalates