CD36 may determine our desire for dietary fats.
There is a strong link between high fat intake and obesity. In addition to its high caloric density, dietary fat has a hyperphagic effect, in part as a result of its high palatability. The recent identification by Laugerette et al. of CD36 as a taste receptor for fatty acids provides insight into the molecular basis of our preference for fat (see the related article beginning on page 3177). As we gain more information regarding the function of this receptor, we may be able to devise better strategies to address the addictive potential of dietary fat.
Abumrad
Nada A
NA
Department of Medicine, Division of Nutritional Science, Washington University School of Medicine, St. Louis, Missouri 63110, USA. nabumrad@wustl.edu
D000818:Animals; D001066:Appetite / Q000276:immunology*; D018955:CD36 Antigens / Q000502:physiology*; D004041:Dietary Fats; D006801:Humans; D013650:Taste Buds / Q000378:metabolism* / Q000502:physiology
D018955:CD36 Antigens; D004041:Dietary Fats