title: Acute bacterial meningitis in a patient receiving ibuprofen.
abstract: We report an atypical presentation of meningitis due to Neisseria meningitidis in a patient who received large doses of ibuprofen. Anti-inflammatory therapy such as NSAIDs could reduce CSF inflammation and modify the clinical outcome in patients with bacterial meningitis. However, the use of NSAIDs is not recommended in bacterial meningitis due to a lack of studies.
authors.affiliation: Department of Infectious Diseases, Pitié-Salpêtrière Hospital, 47-83 Boulevard de l'Hôpital, 75651 Paris, Cedex 13-France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Tamburini
authors.forename: David
authors.initials: D
authors.lastname: Grimaldi
authors.forename: François
authors.initials: F
authors.lastname: Bricaire
authors.forename: Philippe
authors.initials: P
authors.lastname: Bossi
mesh_terms: D000293:Adolescent; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000075202:Contraindications; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008218:Lymphocytosis / Q000209:etiology; D008297:Male; D008585:Meningitis, Meningococcal / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000188:drug therapy / Q000382:microbiology; D009345:Neisseria meningitidis / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000658:Amoxicillin; D007052:Ibuprofen