title: Exploring and engineering the cell surface interface.
abstract: Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of chemistry and topography. We review current approaches to control cell behavior through the nanoscale engineering of materials surfaces. Far-reaching implications are emerging for applications including medical implants, cell supports, and materials that can be used as instructive three-dimensional environments for tissue regeneration.
authors.affiliation: Department of Materials and Institute for Biomedical Engineering, Imperial College of Science, Technology, and Medicine, Prince Consort Road, London SW7 2BP, UK. m.stevens@imperial.ac.uk
authors.forename: Molly M
authors.initials: MM
authors.lastname: Stevens
authors.forename: Julian H
authors.initials: JH
authors.lastname: George
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002462:Cell Membrane / Q000502:physiology*; D002468:Cell Physiological Phenomena; D005109:Extracellular Matrix / Q000502:physiology*; D005544:Forecasting; D006801:Humans; D036103:Nanotechnology / Q000639:trends*; D013499:Surface Properties; D023822:Tissue Engineering / Q000639:trends
chemical_list: D001672:Biocompatible Materials