Anion recognition using preorganized thiourea functionalized [3]polynorbornane receptors.
[structure: see text] A new family of [3]polynorbornane frameworks exhibiting conformationally preorganized aromatic thiourea (cleft-like) receptors have been designed and synthesized for anion recognition. These show excellent affinity for the biologically relevant dihydrogenphosphate (H(2)PO(4)(-)) and dihydrogenpyrophosphate (H(2)P(2)O(7)(2)(-)) anions (among others), which are bound in 1:1 and 2:1 (host:anion) ratio, respectively. Moreover, visually striking color changes accompany guest binding, enabling this family to act as colorimetric anion sensors.
Pfeffer
Frederick M
FM
School of Biological and Chemical Sciences, Deakin University, Waurn Ponds 3217, Australia. thefef@deakin.edu.au
Gunnlaugsson
Thorfinnur
T
Jensen
Paul
P
Kruger
Paul E
PE
D000838:Anions / Q000737:chemistry; D003124:Colorimetry; D015394:Molecular Structure; D009636:Norbornanes / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013890:Thiourea / Q000737:chemistry*
D000838:Anions; D009636:Norbornanes; D011108:Polymers; D013890:Thiourea