Large-scale approaches for glycobiology.
Glycosylation, the attachment of carbohydrates to proteins and lipids, influences many biological processes. Despite detailed characterization of the cellular components that carry out glycosylation, a complete picture of a cell's glycoconjugates remains elusive because of the challenges inherent in characterizing complex carbohydrates. This article reviews large-scale techniques for accelerating progress in glycobiology.
Campbell
Christopher T
CT
Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Yarema
Kevin J
KJ
D001671:Biochemistry / Q000379:methods*; D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000737:chemistry; D006031:Glycosylation; D050356:Lipid Metabolism; D046228:Microarray Analysis; D008954:Models, Biological; D015394:Molecular Structure; D011506:Proteins / Q000378:metabolism
D002241:Carbohydrates; D011506:Proteins