title: Signal-mediated export of proteins from the malaria parasite to the host erythrocyte.
abstract: Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes, asexual stages from the most virulent malaria parasite, P. falciparum, drastically change their host cell and export remodelling and virulence proteins. Recent data demonstrate that a specific NH(2)-terminal signal conserved across the genus Plasmodium plays a central role in this export process.
authors.affiliation: The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia.
authors.forename: Matthias
authors.initials: M
authors.lastname: Marti
authors.forename: Jake
authors.initials: J
authors.lastname: Baum
authors.forename: Melanie
authors.initials: M
authors.lastname: Rug
authors.forename: Leann
authors.initials: L
authors.lastname: Tilley
authors.forename: Alan F
authors.initials: AF
authors.lastname: Cowman
mesh_terms: D000818:Animals; D001692:Biological Transport; D004910:Erythrocyte Membrane / Q000469:parasitology; D004912:Erythrocytes / Q000469:parasitology*; D006790:Host-Parasite Interactions; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology; D008954:Models, Biological; D010963:Plasmodium falciparum / Q000378:metabolism* / Q000502:physiology*; D021381:Protein Transport; D015398:Signal Transduction