title: Pineal cyst apoplexy: case report and review of the literature.
abstract: OBJECTIVE
  Although most pineal cysts are clinically benign and asymptomatic, some can become symptomatic. Of the various symptomatic presentations, apoplexy is the rarest and most ill-defined. A comprehensive search of publications in the English language yielded 18 cases of pineal cyst apoplexy. We reviewed the literature to compare symptomatology and management strategies and their outcomes.
  
  
  METHODS
  A 29-year-old woman with a 1-month history of headaches presented with an acute worsening of her symptoms with a severe occipital headache and trouble focusing when reading. Her neurological examination was otherwise normal. Magnetic resonance imaging showed pineal cyst apoplexy and accompanying hydrocephalus.
  
  
  METHODS
  A left paramedian craniotomy with a transcallosal, transchoroidal approach using an intraoperative neuronavigation system was used to resect a pineal cyst. Postoperative imaging showed complete removal of the cyst and resolution of the hydrocephalus. Follow-up imaging at 12 months demonstrated no evidence of recurrence or any hydrocephalus. The patient has remained asymptomatic for 18 months.
  
  
  CONCLUSIONS
  Pineal cyst apoplexy should always be considered when following a patient with a pineal cyst that becomes symptomatic. The most common symptom was severe headache of sudden onset or acute worsening. Other signs of hydrocephalus may or may not be present. Magnetic resonance imaging is essential to making a diagnosis. Although we believe that surgical resection is the most effective approach because it minimizes the risk for recurrence and complication, stereotactic aspiration has been used successfully to treat this condition.
authors.affiliation: Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4950, USA.
authors.forename: Akash J
authors.initials: AJ
authors.lastname: Patel
authors.forename: Gregory N
authors.initials: GN
authors.lastname: Fuller
authors.forename: David M
authors.initials: DM
authors.lastname: Wildrick
authors.forename: Raymond
authors.initials: R
authors.lastname: Sawaya
mesh_terms: D000328:Adult; D003399:Craniotomy / Q000379:methods; D003560:Cysts / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology / Q000601:surgery; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000379:methods; D038361:Neuronavigation / Q000379:methods; D010870:Pineal Gland / Q000473:pathology* / Q000601:surgery; D020521:Stroke / Q000209:etiology / Q000473:pathology / Q000601:surgery*