title: Primary orbital Ewing sarcoma in a middle-aged man.
abstract: A 54-year-old man presented with a painful left proptosis and a soft tissue mass at the inferolateral aspect of the left orbit with bone involvement. There was no clinical or investigational evidence of systemic disease. Both light microscopy and immunohistochemistry were required for the diagnosis of Ewing sarcoma. After failure of chemotherapy alone, management included extensive surgical excision and postoperative adjuvant radiotherapy and chemotherapy. Despite intervention, the patient died of widespread metastatic disease 17 months after initial presentation. Although rare, Ewing sarcoma should be included in the differential diagnosis of uniform round cell orbital tumors in adults.
authors.affiliation: Department of Ophthalmology, Westmead Hospital, Westmead, Australia.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Guzowski
authors.forename: Krishna
authors.initials: K
authors.lastname: Tumuluri
authors.forename: D M
authors.initials: DM
authors.lastname: Walker
authors.forename: Anthony
authors.initials: A
authors.lastname: Maloof
mesh_terms: D001706:Biopsy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D012512:Sarcoma, Ewing / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D014057:Tomography, X-Ray Computed