Macrophage activation unveiled.
In the early 1960s, George Mackaness showed that macrophages from mice infected with intracellular bacteria could launch an indiscriminate attack against unrelated bacteria. Thus began an explosion of research on the biology of what Mackaness first termed "macrophage activation."
D000486:Allergy and Immunology / Q000266:history*; D049673:History, 20th Century; D008262:Macrophage Activation / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*