Lasers in cancer detection and diagnosis research: enabling characteristics with illustrative examples.
The salient properties of laser light and the way light interacts with biological tissues and molecular constituents of tissues offer possibilities for detection and diagnosis of cancer. In particular, the wavelength selectivity of tunable lasers, narrow bandwidth around the selected wavelength, and spectral brightness enable probing of key molecular constituents of tissues, and endow laser-based techniques with much desired diagnostic potential. This article presents an overview of some recent developments in optical imaging and optical biopsy of different types of cancers, and illustrates the diagnostic role of the color of light.
Alfano
Scott
S
Union College, Schenectady, New York 12308, USA.
Wang
W B
WB
Gayen
S K
SK
D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis*; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007834:Lasers; D008297:Male; D055095:Optics and Photonics; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D013059:Spectrum Analysis, Raman