title: Dengue in the Dominican Republic: epidemiology for 2004.
abstract: The Dominican Republic (DR) has experienced tremendous increase in the number of cases of dengue virus (DENV) reported in the past few years. There are four serotypes of DENV (1-4), and each can cause classic dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). DENV-1-4 are currently circulating in the DR; however, the Department of Epidemiology of the Dominican Republic (DIEGPI) has been able to isolate only DENV-2 and DENV-4. In the DR, the development of DENV infection occurred primarily in the second semester of the year. Since the DR instituted a vigilant approach to dengue infections, there have been three major outbreaks detected: one in 1998, one in 2000, and one in 2002. DF is the clinical presentation most currently seen at clinics, accounting for about 75% of cases, while patients with DHF account for about 19% of cases seen. Currently, there are seven provinces in which the total number of dengue cases per 100,000 inhabitants is higher than 32. With a vigilant approach, the DR should continue to see success in controlling the DENV outbreak.
authors.affiliation: Dominican Republic Directorate of Epidemiology.
authors.forename: Brinia
authors.initials: B
authors.lastname: Cabrera-Batista
authors.forename: Ronald
authors.initials: R
authors.lastname: Skewes-Ramm
authors.forename: Cesar D
authors.initials: CD
authors.lastname: Fermin
authors.forename: Robert F
authors.initials: RF
authors.lastname: Garry
mesh_terms: D004279:DNA, Viral / Q000032:analysis; D003715:Dengue / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D004196:Disease Outbreaks; D004293:Dominican Republic / Q000453:epidemiology; D006801:Humans; D017720:Molecular Epidemiology
chemical_list: D004279:DNA, Viral