Life-threatening meningitis resulting from transrectal prostate biopsy.
After antibiotic prophylaxis with metronidazole and levofloxacin, a transrectal sextant biopsy was performed under the guide of transrectal ultrasonography (TRUS) for a 75-year-old suspicious patient with prostate adenocarcinoma. Although antibiotics were also given after this procedure, the patient still developed fever, anxious, agrypnia and headache. Blood cultures remained negative. Lumbar puncture was performed and was consistent with Escherichia coli bacterial meningitis.
Shen
Zhou-Jun
ZJ
Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China. shenzhj@mail.hz.zj.cn
Chen
Shan-Wen
SW
Wang
Hua
H
Zhou
Xie-Lai
XL
Zhao
Ju-Ping
JP
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage; D001706:Biopsy / Q000009:adverse effects*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008581:Meningitis / Q000209:etiology* / Q000382:microbiology / Q000517:prevention & control; D008795:Metronidazole / Q000008:administration & dosage; D015242:Ofloxacin / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000473:pathology*; D036761:Ultrasound, High-Intensity Focused, Transrectal
D000890:Anti-Infective Agents; D000892:Anti-Infective Agents, Urinary; D008795:Metronidazole; D064704:Levofloxacin; D015242:Ofloxacin