title: Cloning and functional analysis of the gene encoding the 33- to 36-kilodalton outer membrane protein associated with carbapenem resistance in Acinetobacter baumannii.
abstract: We investigated a multiresistant strain of Acinetobacter baumannii isolated in our hospital. Analysis of the N-terminal peptide sequence of the outer membrane proteins (OMPs) purified from the strain allowed us to clone and sequence the nucleotides of the gene encoding the 33- to 36-kDa OMP associated with carbapenem resistance in A. baumannii.
authors.affiliation: Servicio de Microbiologia-Unidad de Investigacion, Complejo Hospitalario Universitario Juan Canalejo, As Xubias, 84, 15006 La Coruña, Spain.
authors.forename: Maria
authors.initials: M
authors.lastname: del Mar Tomás
authors.forename: Alejandro
authors.initials: A
authors.lastname: Beceiro
authors.forename: Astrid
authors.initials: A
authors.lastname: Pérez
authors.forename: David
authors.initials: D
authors.lastname: Velasco
authors.forename: Rita
authors.initials: R
authors.lastname: Moure
authors.forename: Rosa
authors.initials: R
authors.lastname: Villanueva
authors.forename: Jesús
authors.initials: J
authors.lastname: Martínez-Beltrán
authors.forename: Germán
authors.initials: G
authors.lastname: Bou
mesh_terms: D000150:Acinetobacter / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D015780:Carbapenems / Q000378:metabolism / Q000494:pharmacology*; D003001:Cloning, Molecular; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D008970:Molecular Weight
chemical_list: D001425:Bacterial Outer Membrane Proteins; D015780:Carbapenems