title: A convenient method for synthesizing modified 4-nitrophenols.
abstract: [reaction: see text] Beta-nitroenamine having a formyl group behaves as the synthetic equivalent of unstable nitromalonaldehyde upon treatment with ketones under basic conditions and leads to 2,6-disubstituted 4-nitrophenols. The present method is safer than the conventional one using sodium nitromalonaldehyde and enables the preparation of hitherto unknown nitrophenols.
authors.affiliation: Department of Chemistry, Osaka Kyoiku University, Asahigaoka 4-698-1, Kashiwara, Osaka 582-8582, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Nakaike
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kamijo
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mori
authors.forename: Mina
authors.initials: M
authors.lastname: Tamura
authors.forename: Nagatoshi
authors.initials: N
authors.lastname: Nishiwaki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ariga
mesh_terms: D015394:Molecular Structure; D009596:Nitrophenols / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D009596:Nitrophenols; C024836:4-nitrophenol