title: Soluble CD40 ligand levels in patients with hypertension.
abstract: CD40 ligand interaction with its receptor (CD40) not only mediates lymphocyte communication, but also associates with chronic inflammation and atherothrombosis. High soluble CD40L (sCD40L) levels were reported in dyslipidemia, diabetes mellitus, and coronary disease. So far, there are no data about sCD40L levels in hypertension. We investigated sCD40L and high sensitive C reactive protein (hsCRP) levels in 30 nonobese young hypertensive men and 30 matched controls. sCD40L and hsCRP levels were not different, and there were no correlations between blood pressure and sCD40L or hsCRP levels. These results might indicate lack of any inflammatory state in new onset hypertension.
authors.affiliation: Department of Internal Medicine, Gulhane School of Medicine, Etlik Ankara, Turkey. alpersonmez@yahoo.com
authors.forename: Alper
authors.initials: A
authors.lastname: Sonmez
authors.forename: T
authors.initials: T
authors.lastname: Dogru
authors.forename: M I
authors.initials: MI
authors.lastname: Yilmaz
authors.forename: R
authors.initials: R
authors.lastname: Ocal
authors.forename: T
authors.initials: T
authors.lastname: Ozgurtas
authors.forename: S
authors.initials: S
authors.lastname: Kilic
authors.forename: T
authors.initials: T
authors.lastname: Eyileten
authors.forename: I
authors.initials: I
authors.lastname: Tasci
authors.forename: K
authors.initials: K
authors.lastname: Erbil
authors.forename: I H
authors.initials: IH
authors.lastname: Kocar
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000032:analysis; D023201:CD40 Ligand / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000276:immunology / Q000503:physiopathology*; D007249:Inflammation / Q000503:physiopathology; D008297:Male
chemical_list: D023201:CD40 Ligand; D002097:C-Reactive Protein