title: Stigmatization in Alzheimer's disease research on African American elders.
abstract: Stigmatization in research sustains the spread of the silent epidemic of Alzheimer's disease (AD) in African American populations. Researchers use stereotypes and inappropriate assumptions to select a paradigm to examine the symptoms of AD. This paradigm fails to encompass the symptoms as manifested by African American elders. Yet, stigmatization can be minimized by recognizing the genetic heterogeneity of the symptoms within the general population, especially those manifested by African American elders. Thus, researchers can utilize pioneering genetic analyses to identify other paradigms critical in the assessment and proactive treatment of the symptoms of AD needed for this vulnerable population.
authors.affiliation: University of California, Los Angeles, CA, USA. echolston@ucla.edu
authors.forename: Ezra C
authors.initials: EC
authors.lastname: Holston
mesh_terms: D000203:Activities of Daily Living; D001741:Black or African American / Q000208:ethnology / Q000235:genetics; D000368:Aged / Q000523:psychology / Q000706:statistics & numerical data; D000544:Alzheimer Disease / Q000208:ethnology / Q000235:genetics; D001053:Apolipoproteins / Q000235:genetics; D053399:Apolipoproteins D; D001057:Apolipoproteins E / Q000235:genetics; D001291:Attitude of Health Personnel / Q000208:ethnology; D001294:Attitude to Health / Q000208:ethnology; D015984:Causality; D003071:Cognition; D018450:Disease Progression; D018740:Genetic Heterogeneity; D014644:Genetic Variation / Q000235:genetics; D005826:Genetics, Medical / Q000458:organization & administration*; D015577:Geriatric Assessment; D006801:Humans; D008032:Limbic System / Q000503:physiopathology; D008565:Membrane Proteins / Q000235:genetics; D053764:Presenilin-1; D053766:Presenilin-2; D012106:Research / Q000458:organization & administration*; D013240:Stereotyping; D035862:Vulnerable Populations / Q000208:ethnology / Q000706:statistics & numerical data
chemical_list: D001053:Apolipoproteins; D053399:Apolipoproteins D; D001057:Apolipoproteins E; D008565:Membrane Proteins; C508853:PSEN1 protein, human; C508861:PSEN2 protein, human; D053764:Presenilin-1; D053766:Presenilin-2