title: Efficacy and complications of Angioseal in antegrade puncture.
abstract: OBJECTIVE
  Although arterial closure devices are in use for over a decade, there have been no specific study to assess the use of the same in antegrade puncture.
  
  
  METHODS
  Consecutive patients undergoing antegrade puncture for peripheral vascular disease in a single centre performed by a single operator were included in this study. The notes and the angiograms were reviewed retrospectively for possible complications and the severity of disease.
  
  
  RESULTS
  Over a 25-month period, 21 patients with antegrade puncture had Angioseal deployed for haemostasis. Post-procedure complications recorded from the case notes showed one episode of haematoma formation and one case of worsening ischaemia. The severity of the disease at the puncture site did not influence the outcome.
  
  
  CONCLUSIONS
  Use of Angioseal is safe and effective in antegrade punctures for peripheral vascular disease. The result is independent of the severity of disease at the puncture site.
authors.affiliation: Derriford Hospital, Plymouth, UK. kausik@lycos.co.uk
authors.forename: Kausik
authors.initials: K
authors.lastname: Mukhopadhyay
authors.forename: M A
authors.initials: MA
authors.lastname: Puckett
authors.forename: C A
authors.initials: CA
authors.lastname: Roobottom
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006489:Hemostatic Techniques / Q000009:adverse effects* / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D011677:Punctures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome