title: [Chronic immune thrombocytopenic purpura in pregnancy--a case report].
abstract: The authors present a young woman with chronic immune thrombocytopenic purpura during pregnancy. This association is the commonest cause of thrombycitopenia in the first three months of pregnancy. There is a bigger number of spontaneous abortions and more frequent bleeding in such patients, during delivery, in mothers and babies too. The number of mothers platelets and the level of circulating IgG antibodies associated to the mothers platelets are not reliable indicators of the fetus platelets number. Only reliable way for determination of the fetus platelets number is percutaneous umbilical cord blood sampling. Five days before delivery the fetus platelets number have been determinated by this method, and it was 260 x 10(9)/l. Mother was prepared for delivery with high doses of prednisone of 1 mg/kg body weight. Her platelets number was 128 x 10(9)/l on the day of delivery. Delivery has been performed by vaginaly route without complications. Healthy female baby was born.
authors.affiliation: Institute of Haematology, Clinical Centre of Serbia, Belgrade.
authors.forename: R
authors.initials: R
authors.lastname: Miloshevitsh
authors.forename: N
authors.initials: N
authors.lastname: Suvajdzhitsh
authors.forename: D
authors.initials: D
authors.lastname: Pletshash
authors.forename: M
authors.initials: M
authors.lastname: Cholovitsh
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D005312:Fetal Blood / Q000166:cytology; D006801:Humans; D007231:Infant, Newborn; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000628:therapy; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000628:therapy