Revisiting unilateral neglect.
Unilateral neglect, a neurological disorder in which patients fail to detect or respond to contralesional stimuli, has long been considered a failure of attentional orienting mechanisms. This review provides a selective overview of the prominent biases in spatial orienting and exploratory motor behaviour observed in these patients before considering the impact of other factors on the presentation of the disorder and how those factors might inform current neurological models of neglect. In the latter part of the review, we intend to suggest that neglect is likely to be a combination of distinct but interacting impairments including biases in attentional orienting, exploratory motor behaviours and a deficit of spatial working memory. That is, we suggest that the cardinal symptom of neglect - a loss of awareness for contralesional stimuli and events - arises as a result of a combination of these impairments rather than being associated solely with the more dramatic and immediately evident biases in spatial attention.
Danckert
James
J
Canada Research Chair (Tier II) in Cognitive Neuroscience, Department of Psychology, University of Waterloo, 200 University Avenue West, Waterloo, Ont., Canada N2L 3G1. jdancker@uwaterloo.ca
Ferber
Susanne
S
D000818:Animals; D001288:Attention / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology; D009043:Motor Activity / Q000502:physiology; D009949:Orientation / Q000502:physiology; D010468:Perceptual Disorders / Q000473:pathology / Q000503:physiopathology*; D013028:Space Perception / Q000502:physiology