title: Evolution: natural selection in the evolution of humans and chimps.
abstract: We now have more or less full sequences of both human and chimp genomes, allowing comparison that sheds light on their evolution. A few hundred genes show significant evidence for adaptive evolution in the two lineages, but the actual number might be much higher. Natural selection has eliminated about 75% of amino acid changes in coding sequence since the split of the human and chimpanzee genomes.
authors.affiliation: Department of Evolutionary Biology, Uppsala University, Sweden.
authors.forename: Hans
authors.initials: H
authors.lastname: Ellegren
mesh_terms: D000220:Adaptation, Biological / Q000235:genetics*; D000818:Animals; D019143:Evolution, Molecular; D016678:Genome; D023281:Genomics / Q000639:trends*; D006801:Humans; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics; D002679:Pan troglodytes / Q000235:genetics*; D012641:Selection, Genetic; D012737:Sex Factors; D013045:Species Specificity