Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis.
Nonhost resistance describes the immunity of an entire plant species against nonadapted pathogen species. We report that Arabidopsis PEN2 restricts pathogen entry of two ascomycete powdery mildew fungi that in nature colonize grass and pea species. The PEN2 glycosyl hydrolase localizes to peroxisomes and acts as a component of an inducible preinvasion resistance mechanism. Postinvasion fungal growth is blocked by a separate resistance layer requiring the EDS1-PAD4-SAG101 signaling complex, which is known to function in basal and resistance (R) gene-triggered immunity. Concurrent impairment of pre- and postinvasion resistance renders Arabidopsis a host for both nonadapted fungi.
Lipka
Volker
V
Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Carl von Linné Weg 10, D-50829 Köln, Germany.
Dittgen
Jan
J
Bednarek
Pawel
P
Bhat
Riyaz
R
Wiermer
Marcel
M
Stein
Monica
M
Landtag
Jörn
J
Brandt
Wolfgang
W
Rosahl
Sabine
S
Scheel
Dierk
D
Llorente
Francisco
F
Molina
Antonio
A
Parker
Jane
J
Somerville
Shauna
S
Schulze-Lefert
Paul
P
D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics / Q000276:immunology* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000502:physiology*; D001203:Ascomycota / Q000502:physiology; D002265:Carboxylic Ester Hydrolases / Q000502:physiology; D004268:DNA-Binding Proteins / Q000502:physiology; D009154:Mutation; D009699:N-Glycosyl Hydrolases / Q000502:physiology*; D020675:Peroxisomes / Q000502:physiology; D010838:Phytophthora / Q000502:physiology; D010935:Plant Diseases / Q000382:microbiology*; D050765:Qa-SNARE Proteins / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction
D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; C118837:EDS1 protein, Arabidopsis; C479425:PEN1 protein, Arabidopsis; D050765:Qa-SNARE Proteins; D002265:Carboxylic Ester Hydrolases; C400766:PAD4 protein, Arabidopsis; C460108:SAG101 protein, Arabidopsis; D009699:N-Glycosyl Hydrolases; C505663:PEN2 protein, Arabidopsis