title: Conservative local treatment versus mastectomy after induction chemotherapy in locally advanced breast cancer: a randomised phase III study (EORTC 10974/22002, LAMANOMA)--why did this study fail?
authors.affiliation: Department of Oncology and Radiotherapy, Medical University of Gdansk, ul. Debinki, 7, 80-211 Gdansk, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Sinacki
authors.forename: Jacek
authors.initials: J
authors.lastname: Jassem
authors.forename: Geertjan
authors.initials: G
authors.lastname: van Tienhoven
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery*; D017326:Clinical Trials, Phase III as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods*; D015337:Multicenter Studies as Topic; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic
chemical_list: D000970:Antineoplastic Agents