title: Wireless electrodeless piezomagnetic biosensor with an isolated nickel oscillator.
abstract: This study presents a fundamental concept of piezomagnetic biochemical sensor driven in a wireless-electrodeless manner. A stepped cylindrical rod of nickel is used as the oscillator, which traps the vibrational energy of axially-polarized surface-shear waves in the central part, where the diameter is slightly larger. A meander-line coil surrounding the oscillator with an air gap can cause and detect the resonant vibrations of the surface-shear waves via the piezomagnetic effect. The resonant frequency of the trapped-mode resonance is continuously measured to detect human immunoglobulin G (IgG). It decreased by 0.08% when a solution containing IgG was injected into the glass cell where the oscillator was placed alone. This oscillator is useful for fundamental studies of various biochemical reactions in a closed system in different environmental gases and different pressures.
authors.affiliation: Graduate School of Engineering Science, Osaka University, Machikaneyama 1-3, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Ogi
authors.forename: Kazuma
authors.initials: K
authors.lastname: Motohisa
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Tomoo
authors.initials: T
authors.lastname: Mizugaki
authors.forename: Masahiko
authors.initials: M
authors.lastname: Hirao
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D009532:Nickel; D013205:Staphylococcal Protein A / Q000032:analysis
chemical_list: D007074:Immunoglobulin G; D013205:Staphylococcal Protein A; D009532:Nickel