title: Enol tosylates as viable partners in Pd-catalyzed cross-coupling reactions.
abstract: [reaction: see text] Herein we demonstrate functionalized enol tosylates to be robust substrates that undergo Suzuki-Miyaura, Sonogashira, and Stille cross-coupling reactions to provide stereodefined trisubstituted unsaturated esters.
authors.affiliation: Department of Process Research, Merck & Co., Inc., P.O. Box 2000, Rahway, New Jersey 07065, USA. dietrich_steinhuebel@merck.com
authors.forename: Dietrich
authors.initials: D
authors.lastname: Steinhuebel
authors.forename: Jenny M
authors.initials: JM
authors.lastname: Baxter
authors.forename: Michael
authors.initials: M
authors.lastname: Palucki
authors.forename: Ian W
authors.initials: IW
authors.lastname: Davies
mesh_terms: D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D014105:Tosyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D014105:Tosyl Compounds; D010165:Palladium