[Expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex of postnatal mice].
OBJECTIVE
To study the expression of Runx2/Cbfa1 in the developing dentin and differentiating odontoblasts.


METHODS
A postnatal mice teeth developing model was built histologically. Immunohistochemical technique was adopted to determine the expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex in mice.


RESULTS
Runx2/Cbfa1 was merely present in predentin in the exact and before the 11th day's postnatal stages. Meanwhile, it was positively located in odontoblasts and dental pulp cells in root region, but negatively in coral part after the 11th day's stages.


CONCLUSIONS
Runx2/Cbfa1 may play an important role in the deposing of tooth dentin and in the differentiating of odontoblasts and pulp cells.
Pan
Ke-qing
KQ
Dept. of Periodontology, School of Stomatology, Shandong University, Jinan 250012, China.
Li
Shu
S
Yang
Pi-shan
PS
Zhao
Yan-hong
YH
D000818:Animals; D002454:Cell Differentiation; D050659:Core Binding Factor Alpha 1 Subunit; D003782:Dental Pulp; D003804:Dentin; D051379:Mice; D009804:Odontoblasts; D014070:Tooth
D050659:Core Binding Factor Alpha 1 Subunit