title: Interhospital transportation of patients with severe lung failure on pumpless extracorporeal lung assist.
abstract: BACKGROUND
  To describe the use of pumpless extracorporeal interventional lung assist (iLA) for transportation of patients with severe life-threatening acute lung failure from tertiary hospitals to a specialized centre.
  
  
  METHODS
  Retrospective analysis in eight patients with severe lung failure requiring interhospital transport, in whom implementation of an iLA system at a tertiary hospital for air/ground transportation was performed.
  
  
  RESULTS
  After implementation of iLA, a rapid increase in CO2-elimination (Pa(CO2) before iLA: 8.92+/-2.9 kPa, immediately after implementation: 5.06+/-0.93 kPa, 24 h after implementation: 4.53+/-1.20 kPa [mean+/-SD], P<0.05) was observed and a significant improvement in oxygenation (Pa(O2) before iLA: 6.66+/-2.26 kPa, immediately after implementation: 10.39+/-3.33 kPa, 24 h after implementation: 10.25+/-5.46 kPa, P<0.05) was noted. During transport, no severe complications occurred. Four patients died during further treatment due to multiple trauma or multiple organ failure.
  
  
  CONCLUSIONS
  Due to ease of handling, high effectiveness and relatively low costs, iLA seems to be a useful system for treatment and transportation of patients with severe acute lung injury or ARDS suffering from life-threatening hypoxia and/or hypercapnia.
authors.affiliation: Department of Anesthesiology, University of Regensburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Zimmermann
authors.forename: T
authors.initials: T
authors.lastname: Bein
authors.forename: A
authors.initials: A
authors.lastname: Philipp
authors.forename: K
authors.initials: K
authors.lastname: Ittner
authors.forename: M
authors.initials: M
authors.lastname: Foltan
authors.forename: J
authors.initials: J
authors.lastname: Drescher
authors.forename: F
authors.initials: F
authors.lastname: Weber
authors.forename: F-X
authors.initials: FX
authors.lastname: Schmid
mesh_terms: D000328:Adult; D017732:Air Ambulances; D002245:Carbon Dioxide / Q000097:blood; D015199:Extracorporeal Membrane Oxygenation / Q000295:instrumentation / Q000379:methods*; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011659:Pulmonary Gas Exchange; D012128:Respiratory Distress Syndrome / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D014187:Transportation of Patients / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen