title: [Revised criteria for the early diagnosis of diabetic nephropathy].
abstract: The Diabetic Nephropathy Committee recommends the use of revised criteria for the early diagnosis of diabetic nephropathy in Japan. The new criteria are as follows: 1) Urinary albumin should be determined by immunoassay using a morning spot urine sample in diabetic patients without proteinuria or with dipstick-positive(+ 1) proteinuria. 2) A urinary albumin-to-creatinine ratio ranging from 30 to 299 mg/ gCr in 2 or more of 3 specimens may be diagnosed as microalbuminuria. 3) Two alternatives, i.e. the urinary albumin excretion rate of 30-299 mg/24hr in 24hr urine collection or 20-199 microg/min in timed urine collection can be used to detect microalbuminuria. 4) Renal hypertrophy and elevated urinary type IV collagen may indicate the existence of diabetic renal disease. 5) Microalbuminuria originating in non-diabetic diseases should be excluded.
authors.affiliation: Japanese Society of Nephrology.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Inomat
authors.forename: Masakazu
authors.initials: M
authors.lastname: Haneda
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Moriya
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Katayama
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Iwamoto
authors.forename: Hideto
authors.initials: H
authors.lastname: Sakai
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tomino
authors.forename: Seiichi
authors.initials: S
authors.lastname: Matsuo
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Asano
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Makino
mesh_terms: D000419:Albuminuria / Q000175:diagnosis; D015415:Biomarkers / Q000652:urine; D024141:Collagen Type IV / Q000652:urine; D003404:Creatinine / Q000652:urine; D003928:Diabetic Nephropathies / Q000175:diagnosis*; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D006984:Hypertrophy; D007118:Immunoassay / Q000379:methods; D007668:Kidney / Q000473:pathology; D012015:Reference Standards
chemical_list: D015415:Biomarkers; D024141:Collagen Type IV; D003404:Creatinine