Prenatal MR diffusion-weighted imaging in a fetus with hemimegalencephaly.
We report a case of hemimegalencephaly diagnosed by prenatal MRI with an emphasis on its appearance on diffusion-weighted images. This case shows that in this condition the enlarged hemisphere may show restricted diffusion on prenatal MRI. In our opinion, this finding may result from a combination of increased cellularity and advanced myelination in the affected hemisphere. Restricted diffusion is an additional valuable indicator in the analysis of the fetal brain.
Agid
Ronit
R
Division of Neuroradiology, Department of Radiology, Hadassah University Hospital, Kiryat Hadassah, Ein-Karem, P.O. Box 12000, Jerusalem, Israel. ronitagid@hotmail.com
Lieberman
Sivan
S
Nadjari
Michael
M
Gomori
John M
JM
D000328:Adult; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D002552:Cerebral Ventricles / Q000002:abnormalities* / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D009421:Nervous System Malformations / Q000175:diagnosis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis