title: [Small bowel transplantation].
abstract: Early attempts of small bowel transplantation (SBTx) were unsuccessful as a result of uncontrolled rejection and infection. Introduction of tacrolimus in the early 1990s improved the outcome, but results were not satisfactory comparing those after the other organ transplants. Recently, improved long-term graft survivals were reported from several centers. According to Intestine Transplant Registry (ITR), a multivariate analysis of cases within the last 5 years revealed that transplantation of patients waiting at home, recipient age, antibody induced immune suppression, and center experience with at least 10 cases were associated with improved patients survival. One-year graft survival rate of 90% were achieved in patients who were treated with antithymocyte globulin and maintained on tacrolimus.
authors.affiliation: The First Department of Surgery, Hokkaido University School of Medicine.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Shimamura
authors.forename: Masahiko
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Yamashita
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Furukawa
authors.forename: Satoru
authors.initials: S
authors.lastname: Todo
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006084:Graft Rejection / Q000175:diagnosis; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D007223:Infant; D007421:Intestine, Small / Q000637:transplantation*