title: Exercise tolerance and hyperinsulinemia in cardiac syndrome X.
abstract: The aim of the study was to evaluate the relationship between exercise tolerance, glucose and insulin levels and biochemical parameters related to endothelial function [endothelin-1 (ET-1), nitrite/nitrate (NOx)] in patients with cardiological syndrome X in comparison with healthy volunteers. The decrease of NOx level and NOx / ET-1 ratio suggests that endothelial dysfunction is present in cardiological syndrome X. Exercise tolerance correlated positively with NOx and negatively with insulin concentrations.
authors.affiliation: II Klinika Kardiologii Instytutu Kardiologii, Collegium Medicum Uniwersytetu Jagiellońskiego.
authors.forename: Władysława
authors.initials: W
authors.lastname: Kolasilska-Kloch
authors.forename: Wiktoria
authors.initials: W
authors.lastname: Leśniak
authors.forename: Iwona
authors.initials: I
authors.lastname: Leszczyńska-Gołabek
authors.forename: Beata
authors.initials: B
authors.lastname: Kieć-Wilk
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kloch
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D019332:Endothelin-1 / Q000097:blood; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology*; D017079:Exercise Tolerance; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000503:physiopathology*; D007328:Insulin / Q000097:blood; D008297:Male; D017566:Microvascular Angina / Q000097:blood / Q000503:physiopathology*; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D019332:Endothelin-1; D007328:Insulin; D009569:Nitric Oxide