title: Sporadic colonic hamartomas in adults: a retrospective study.
abstract: BACKGROUND
  Colonic hamartomas are uncommon in adults. The aims of this study were to determine (1) the prevalence of colonic hamartomas in an adult population undergoing colonoscopy and (2) the clinical, endoscopic, and histologic features of colonic hamartomas in adult patients.
  
  
  METHODS
  A pathology database identified 19 adult patients of 12,707 patients with colonic hamartomas in the 11-year study period from January 1992 to October 2002. An endoscopic computer database provided information about the number of colonoscopies performed and the presence or the absence of colonic polyp(s) in study patients. Charts of patients with colonic hamartomas were reviewed, and clinical and demographic data were collated.
  
  
  RESULTS
  Nineteen patients were found to have colonic hamartomas. The mean age of these patients was 55 years, with an age distribution ranging from 25 to 81 years. The prevalence of colonic hamartomas in this study population was 0.15%. The prevalence of hamartomas in patients with colon polyps at index colonoscopy was 0.073%. Colonic hamartomas were more common in men than in women. The indication for colonoscopy for the majority (68%) of patients was hematochezia or the presence of occult blood in the stool. Three fourths of the polyps were greater than 1 cm in diameter, and 89% were pedunculated. Two thirds of the hamartomatous polyps were localized to the rectosigmoid region. Endoscopic characteristics of hamartomas were indistinguishable from adenomas.
  
  
  CONCLUSIONS
  Colonic hamartomas in adults are rare. They tend to be single, pedunculated, and localized predominantly in the rectosigmoid region. Endoscopic resection of colonic hamartomas was successful in all patients.
authors.affiliation: Division of Gastroenterology, Department of Medicine, University of Oklahoma Health Sciences Center and Oklahoma City Veterans Affairs Medical Center, Oklahoma City 73104, USA.
authors.forename: Sikandar
authors.initials: S
authors.lastname: Mesiya
authors.forename: Hari B
authors.initials: HB
authors.lastname: Ancha
authors.forename: Hanumantha
authors.initials: H
authors.lastname: Ancha
authors.forename: Stan
authors.initials: S
authors.lastname: Lightfoot
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kida
authors.forename: Ralph
authors.initials: R
authors.lastname: Guild
authors.forename: Richard F
authors.initials: RF
authors.lastname: Harty
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003108:Colonic Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003111:Colonic Polyps / Q000150:complications / Q000473:pathology; D003113:Colonoscopy; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged