title: [Treatment alternatives of the locally advanced prostate cancer].
abstract: Author makes overview on locally advanced prostate cancer. In spite of the effort to make diagnosis in the earliest stage, disease is still pretty often diagnosed in locally advanced stage with significantly higher risk of progression and recurrence. He summarizes current view on available treatment alternatives (radical surgery, radiotherapy, hormonal treatment, chemotherapy) and their possible and proven combinations. Monotherapy is not considered as the optimal alternative, treatment of choices is the multimodal treatment strategy, though some combinations have been already confirmed as inappropriate.
authors.affiliation: Urologická klinika LF MU a FN, Brno. dpacik@fnbrno.cz
authors.forename: D
authors.initials: D
authors.lastname: Pacík
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology / Q000628:therapy*