Recent advances in antiviral nucleoside and nucleotide therapeutics.
Recent developments in nucleoside/nucleotide therapeutics and antiviral drug targets are described covering progress in the development of nucleoside/nucleotide mimetics for the treatment of influenza virus, human immunodeficiency virus type 1, hepatitis B and C virus, herpes virus infections; including herpes simplex virus, cytomegalovirus and varicella zoster virus infections, and the highly pathogenic poxviruses (variola, vaccinia and monkey pox) and filoviruses (Ebola and Marburg).
Simons
Claire
C
Medicinal Chemistry Division, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3XF, UK. SimonsC@Cardiff.ac.uk
Wu
Qinpei
Q
Htar
Thet Thet
TT
D000998:Antiviral Agents / Q000138:chemical synthesis / Q000145:classification / Q000627:therapeutic use*; D006801:Humans; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis / Q000145:classification / Q000627:therapeutic use*; D009711:Nucleotides / Q000138:chemical synthesis / Q000145:classification / Q000627:therapeutic use*; D014777:Virus Diseases / Q000188:drug therapy* / Q000821:virology; D014780:Viruses / Q000187:drug effects*
D000998:Antiviral Agents; D009705:Nucleosides; D009711:Nucleotides