title: Clinical effectiveness of two agents on the treatment of tooth cervical hypersensitivity.
abstract: OBJECTIVE
  To investigate the desensitizing ability of a one-bottle bonding agent and a glutaraldehyde-based HEMA formulation on sensitive tooth cervical areas for a period up to 9 months.
  
  
  METHODS
  The sample consisted of 40 patients with cervical hypersensitivity. Three sensitive teeth per patient were treated; one received One-Step (one-bottle bonding agent), the other Gluma Desensitizer (glutaraldehyde-based agent) and the third distilled water (control group). The hypersensitivity level was determined before, immediately after the desensitizing session, at 8 weeks, and 9 months post-treatment. Measurements of sensitivity were determined by the patient's response to tactile and air-blast stimuli. A verbal rating scale was used and scored as follows: 0, no discomfort; 1, discomfort but no severe pain; 2, severe pain during simulation; 3, severe pain after simulation. The results were subjected to statistical analysis by Kruskal-Wallis test (a=0.05).
  
  
  RESULTS
  Both treatment procedures resulted in reduction of hypersensitivity to both stimuli, for up to 9 months. No significant differences were recorded between One-Step and Gluma Desensitizer at immediate and 8-week examinations, whereas Gluma Desensitizer produced lower hypersensitivity than One-Step at the 9-month assessment. In general, a lower level of reduction was found for the 9-month interval compared to the 8-week hypersensitivity score for both agents tested. A placebo effect was observed with water treatment, ranging from 4.7 to 27.5% reduction of hypersensitivity.
authors.affiliation: Department of Operative Dentistry, Faculty of Dentistry, University of Athens, 2 Thivon Str, 115 27 Goudi, Athens, Greece. afrodite1@otenet.gr
authors.forename: Afrodite
authors.initials: A
authors.lastname: Kakaboura
authors.forename: Christos
authors.initials: C
authors.lastname: Rahiotis
authors.forename: Socratis
authors.initials: S
authors.lastname: Thomaidis
authors.forename: Spyridon
authors.initials: S
authors.lastname: Doukoudakis
mesh_terms: D000328:Adult; D000368:Aged; D003806:Dentin Permeability / Q000187:drug effects; D003807:Dentin Sensitivity / Q000188:drug therapy*; D017220:Dentin-Bonding Agents / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005976:Glutaral / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008689:Methacrylates / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D010147:Pain Measurement; D018709:Statistics, Nonparametric; D013997:Time Factors; D019237:Tooth Cervix
chemical_list: C103506:Bis-GMA, BPDM, HEMA dental-bonding resin; D017220:Dentin-Bonding Agents; D008689:Methacrylates; C111486:gluma desensitizer; D005976:Glutaral