title: Lymphoplasmacytic lymphoma with IgA paraproteinemia mimicking Waldenstrom's Macroglobulinemia.
abstract: Central to the diagnosis of Waldenstrom's Macroglobulinemia is the demonstration of bone marrow infiltration by lymphoplasmacytic lymphoma with Ig M monoclonal gammopathy. We describe a patient who presented with a clinical and haematological picture, highly suggestive of Waldenstrom's Macroglobulinemia, but whose serum monoclonal immunoglobulin belonged to Ig A class. Ig A secreting lymphoplasmacytic lymphoma undoubtedly exist but are exceedingly uncommon and their relationship to Waldenstrom's Macroglobulinemia needs to be clarified.
authors.affiliation: Departments of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry. ddbasu@satyam.net.in
authors.forename: Debdatta
authors.initials: D
authors.lastname: Basu
authors.forename: Darshana
authors.initials: D
authors.lastname: Pathak
authors.forename: C
authors.initials: C
authors.lastname: Shyambabu
authors.forename: Bidhan C
authors.initials: BC
authors.lastname: Koner
authors.forename: R P
authors.initials: RP
authors.lastname: Swaminathan
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications / Q000276:immunology*; D008258:Waldenstrom Macroglobulinemia / Q000150:complications / Q000175:diagnosis* / Q000276:immunology
chemical_list: D007070:Immunoglobulin A