title: Management of delayed intracranial and intraspinal metastases of intradural spinal paragangliomas.
abstract: The preferential site of extra-adrenal paragangliomas is the head and neck region. However intradural spinal paragangliomas are commonly described and are considered as benign entities. We report the case of a paraganglioma of the cauda equina followed after complete surgical removal by intracranial and intraspinal cerebrospinal fluid metastases. Seven years after the first operation, a cystic cerebellar lesion was successfully treated by surgery. During a long follow-up, four locations in the posterior fossa, a lumbar recurrence and metastatic nodules at T6 and S1-S2 level were also discovered. Radiotherapy stopped the lesions' growth and allowed improvement of the neurological status. Through a review and analysis of the literature, we discuss the management of this unusual evolution.
authors.affiliation: Department of Neurosurgery, Centre Hospitalier Régional et Universitaire, Lille, France. Laurent.Thines@wanadoo.fr
authors.forename: L
authors.initials: L
authors.lastname: Thines
authors.forename: J P
authors.initials: JP
authors.lastname: Lejeune
authors.forename: M M
authors.initials: MM
authors.lastname: Ruchoux
authors.forename: R
authors.initials: R
authors.lastname: Assaker
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D010235:Paraganglioma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D013904:Thoracic Vertebrae; D013997:Time Factors