title: Osteonecrosis of the metacarpal head in a patient with a prothrombin 20210A gene mutation.
abstract: Osteonecrosis of the metacarpal head is rare and of unknown cause. We describe a 17-year-old girl with osteonecrosis of the fourth metacarpal head and a mutated prothrombin 20210A gene, which suggests a possible relation between a hypercoagulable state and osteonecrosis of the metacarpal head.
authors.affiliation: Department of Hand Surgery, University Hospital Malmö, Malmö, Sweden. anders.bjorkman@hand.mas.lu.se
authors.forename: Anders
authors.initials: A
authors.lastname: Björkman
authors.forename: Peter
authors.initials: P
authors.lastname: Jörgsholm
authors.forename: Isabella M
authors.initials: IM
authors.lastname: Burtscher
mesh_terms: D000293:Adolescent; D016025:Bone Transplantation; D005260:Female; D006801:Humans; D050279:Metacarpal Bones / Q000637:transplantation; D008662:Metacarpophalangeal Joint / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009154:Mutation; D010020:Osteonecrosis / Q000175:diagnosis* / Q000601:surgery; D011516:Prothrombin / Q000235:genetics*; D011884:Radius / Q000637:transplantation; D016059:Range of Motion, Articular / Q000502:physiology
chemical_list: D011516:Prothrombin