title: Metabolic hyperglycemic emergencies with acute pancreatitis in a child with known insulin-dependent diabetes mellitus.
abstract: The combined clinical and biochemical profile of diabetic ketoacidosis, hyperglycemic hyperosmolar non-ketotic syndrome, complicated by acute pancreatitis, in an 11-year-old with established insulin-dependent diabetes mellitus, is presented. The management requires diligent correction of dehydration and hyperglycemia, while monitoring neurological status and blood chemistry. It is imperative to monitor and avoid potentially fatal complications of the combined entity, namely, cerebral edema, thromboembolism, acute respiratory distress syndrome and rhabdomyolysis. Excluding acute pancreatitis in the face of persistent abdominal pain in this setting is emphasized.
authors.affiliation: Division of Critical Care Pediatrics, Miami Children's Hospital, Miami, Florida, USA. tulmula@yahoo.com
authors.forename: Pulin B
authors.initials: PB
authors.lastname: Koul
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Sussmane
mesh_terms: D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D016883:Diabetic Ketoacidosis / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy / Q000209:etiology*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D010195:Pancreatitis / Q000150:complications* / Q000378:metabolism
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin