title: Mediators of inflammatory and ischemic renal damage: the role of neoangiogenesis.
abstract: Neoangiogenesis is at the forefront of research in a number of fields that are of interest to the nephrologist, ranging from the development of the kidney and glomerulus to microvascular injury and its repair. The molecular mechanisms have recently been elucidated to a considerable extent. They are relevant for understanding the link between endothelial cells and podocytes, which underlie the glomerular barrier function. For reasons poorly understood capillarogenesis is defective in renal failure.
authors.affiliation: Department of Pathology, University of Heidelberg, Heidelberg--Germany.
authors.forename: Marie-Luise
authors.initials: ML
authors.lastname: Gross
authors.forename: Marcin
authors.initials: M
authors.lastname: Adamczak
authors.forename: Kerstin
authors.initials: K
authors.lastname: Amann
authors.forename: Eberhard
authors.initials: E
authors.lastname: Ritz
mesh_terms: D000818:Animals; D005260:Female; D005921:Glomerulonephritis / Q000503:physiopathology; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000502:physiology; D018836:Inflammation Mediators / Q000502:physiology*; D007511:Ischemia / Q000503:physiopathology*; D007668:Kidney / Q000098:blood supply*; D007674:Kidney Diseases / Q000503:physiopathology*; D007678:Kidney Glomerulus / Q000098:blood supply; D009389:Neovascularization, Pathologic / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000209:etiology; D011247:Pregnancy; D051437:Renal Insufficiency / Q000503:physiopathology; D015398:Signal Transduction; D042461:Vascular Endothelial Growth Factor A / Q000502:physiology
chemical_list: D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D018836:Inflammation Mediators; D042461:Vascular Endothelial Growth Factor A