title: Low-dose helical chest CT in asbestos-exposed workers in the Veneto Region: preliminary results.
abstract: OBJECTIVE
  To evaluate the preliminary results of low-dose helical chest CT in a group of individuals with an occupational exposure to asbestos.
  
  
  METHODS
  Between October 2000 and May 2004, 1,512 asymptomatic subjects, selected by Occupational Health physicians of the Veneto Region among those with a significant exposure to asbestos, underwent low-dose helical chest CT without contrast media administration. According to their features, all pulmonary nodules identified underwent pathology, further CT evaluation or follow-up with low-dose CT.
  
  
  RESULTS
  Apart from benign pleural findings (in 40% of subjects), 590 pulmonary nodules were identified. Eleven nodules underwent pathologic examination, which detected 5 malignant lesions, and 51 were evaluated with other CT techniques, in all cases demonstrating benign features. In follow-up low-dose CT scans, performed in the remaining 528 nodules, a minimal increase in size occurred in 4 cases only.
  
  
  CONCLUSIONS
  Screening for clinically relevant pulmonary lesions in asymptomatic people with occupational exposure to asbestos may be useful if rigorous enrollment criteria are adopted. The management of abnormal findings is cost-effective if it is based on the morphological features of each finding.
authors.affiliation: Istituto di Radiologia dell'Università, Policlinico G. B. Rossi, Verona, Italy. saminniti@libero.it
authors.forename: Salvatore
authors.initials: S
authors.lastname: Minniti
authors.forename: Marvi
authors.initials: M
authors.lastname: Valentini
authors.forename: Roberto
authors.initials: R
authors.lastname: Pozzi Mucelli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos; D001195:Asbestosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007558:Italy; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D010994:Pleura / Q000000981:diagnostic imaging; D011829:Radiation Dosage; D013902:Radiography, Thoracic; D036542:Tomography, Spiral Computed
chemical_list: D001194:Asbestos