title: Chronic granulomatous disease presenting with eosinophilic inflammation.
abstract: Chronic granulomatous disease (CGD), a rare immunodeficiency, typically presents with recurrent infections caused by catalase-positive organisms. We report 2 patients with CGD who presented with eosinophilic inflammatory conditions recognized before the diagnosis of CGD. Both patients had significant urologic disease. Physicians should be aware of the association of CGD with eosinophilic inflammatory conditions.
authors.affiliation: Division of Infectious Disease, Department of Pediatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA. pjaggi@childrensmemorial.org
authors.forename: Preeti
authors.initials: P
authors.lastname: Jaggi
authors.forename: Alexandra F
authors.initials: AF
authors.lastname: Freeman
authors.forename: Ben Z
authors.initials: BZ
authors.lastname: Katz
mesh_terms: D042441:Achromobacter denitrificans / Q000201:enzymology / Q000302:isolation & purification*; D001228:Aspergillosis / Q000150:complications / Q000175:diagnosis; D001230:Aspergillus / Q000201:enzymology / Q000302:isolation & purification; D002374:Catalase / Q000378:metabolism*; D002675:Child, Preschool; D004804:Eosinophils / Q000276:immunology; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis; D006105:Granulomatous Disease, Chronic / Q000276:immunology* / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007249:Inflammation / Q000276:immunology / Q000382:microbiology*; D008297:Male
chemical_list: D002374:Catalase