Expression of mRNA for inducible NO synthase in human brain.
We studied expression of inducible NO synthase gene in human brain under conditions of acute or chronic intoxication. Acute alcohol intoxication was accompanied by changes in enzyme expression in certain brain structures.
Smolina
I V
IV
Bureau of Forensic Medical Examination, Pacific Ocean Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok. mariyana-z@mail.ru
Kozhemyako
V B
VB
Dirlam
G G
GG
Zavgorodnyaya
M S
MS
Rasskazov
V A
VA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000435:Alcoholic Intoxication / Q000150:complications*; D000438:Alcohols / Q000633:toxicity*; D001921:Brain / Q000187:drug effects* / Q000201:enzymology* / Q000378:metabolism; D018076:DNA, Complementary / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D052247:Nitric Oxide Synthase Type II / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014018:Tissue Distribution
D000438:Alcohols; D018076:DNA, Complementary; D012333:RNA, Messenger; D052247:Nitric Oxide Synthase Type II