Cortical map reorganization without cholinergic modulation.
Acetylcholine has been shown to modulate many forms of cortical plasticity. New evidence indicates that reorganization of adult primary auditory cortex is still possible after removal of cholinergic inputs. This finding suggests that acetylcholine may act less as a gate and more as a gain control on cortical plasticity.
Kilgard
Michael P
MP
Cognition and Neuroscience Program, University of Texas, Dallas, School of Behavioral and Brain Sciences, GR41, Richardson, Texas 75083, USA.
D000109:Acetylcholine / Q000502:physiology*; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001931:Brain Mapping; D009473:Neuronal Plasticity / Q000502:physiology*
D000109:Acetylcholine