Studies on biosynthesis of sterol/steroid from dopamine.
The in vitro incubation of the anterior kidney, posterior kidney, liver, brain, spleen and ovarian tissue homogenates of the fish Nandus nandus with DOPA has been studied with regards to cholesterol production. All tissues except liver give highly positive results. There is also an increase in the neutral 17-ketosteroids. Injections of Dopamine also produce similar results. It is then concluded that DOPA and Dopamine are important precursors of cholesterol in the fish tissues.
Saraf
D K
DK
Zoology Department, University of Saugar, Saugor, MP India.
Shrivastava
R K
RK
D015068:17-Ketosteroids / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002784:Cholesterol / Q000096:biosynthesis*; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D010053:Ovary / Q000187:drug effects / Q000378:metabolism; D010473:Perciformes; D013737:Testis / Q000378:metabolism
D015068:17-Ketosteroids; D004295:Dihydroxyphenylalanine; D002784:Cholesterol; D004298:Dopamine