Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique.
We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood of Beira, Mozambique. The campaign was conducted from December 2003 to January 2004. Overall 98,152 doses were administered, and vaccine coverage of the target population was 58.6% and 53.6% for the first and second rounds, respectively. The direct cost of the campaign, which excludes the price of the vaccine, amounted to slightly over 90,000 dollars, resulting in the cost per fully vaccinated person of 2.09 dollars, which is relatively high. However, in endemic settings where outbreaks are likely to occur, integrating cholera vaccination into the routine activities of the public health system could reduce such costs.
Cavailler
Philippe
P
Epicentre, Paris, France. philippe.cavailler@epicentre.msf.org
Lucas
Marcelino
M
Perroud
Valerie
V
McChesney
Margaret
M
Ampuero
Sonia
S
Guérin
Philippe J
PJ
Legros
Dominique
D
Nierle
Thomas
T
Mahoudeau
Claude
C
Lab
Bruno
B
Kahozi
Pierre
P
Deen
Jacqueline L
JL
von Seidlein
Lorenz
L
Wang
Xuan-Yi
XY
Puri
Mahesh
M
Ali
Mohammad
M
Clemens
John D
JD
Songane
Francisco
F
Baptista
Alberto
A
Ismael
Fauzia
F
Barreto
Avertino
A
Chaignat
Claire-Lise
CL
D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology* / Q000517:prevention & control; D003365:Costs and Cost Analysis; D005260:Female; D006801:Humans; D008297:Male; D032541:Mass Vaccination / Q000191:economics; D009073:Mozambique / Q000453:epidemiology