Synthesis of a 2,3';6',3''-terpyridine scaffold as an alpha-helix mimetic.
[reaction: see text] A terpyridine scaffold has been designed as an alpha-helix mimetic. A facile synthesis of the ortho-functionalized 2,3'-oligopyridine has been accomplished using sequential Bohlmann-Rahtz heteroannulation reactions.
Davis
Jessica M
JM
Department of Chemistry, Yale University, P.O. Box 20810, New Haven, Connecticut 06511, USA.
Truong
Anh
A
Hamilton
Andrew D
AD
D002384:Catalysis; D008968:Molecular Conformation; D018716:Molecular Mimicry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry*
C512247:2,3',6',3''-terpyridine; D011725:Pyridines; D010165:Palladium