Association of childhood acute lymphoblastic leukaemia with cancers in family members.
Children whose twins have had leukaemia have a higher risk of contracting acute lymphoblastic leukaemia (ALL), confirming a prenatal origin of the disease. This association was not true when considering other types of affected first-degree relatives. Children whose fathers were diagnosed with testicular cancer have a higher risk of ALL.
Couto
E
E
Department of Biosciences at Novum, Karolinska Institute, 141 57 Huddinge, Sweden. Elizabeth.couto@biosci.ki.se
Chen
B
B
Hemminki
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology / Q000235:genetics*; D013548:Sweden / Q000453:epidemiology; D013736:Testicular Neoplasms / Q000235:genetics