title: Tandem oxidation processes using manganese dioxide: discovery, applications, and current studies.
abstract: "One-pot" processes in which alcohol oxidations are combined with further elaboration of the carbonyl intermediate are reviewed. Sequential processes are briefly discussed, but most attention is centered on tandem processes; that is, oxidations carried out in the presence of a nucleophilic trapping agent, rather than those in which the trapping agent is added after the oxidation is complete. As part of this Account, a comprehensive review of the discovery of tandem oxidation processes (TOP) will be given together with applications in alkene-forming reactions, cyclopropanations, and imine, oxime, amine, and heterocycle formation.
authors.affiliation: Department of Chemistry, University of York, Heslington, York YO10 5DD , United Kingdom. rjkt1@york.ac.uk
authors.forename: Richard J K
authors.initials: RJ
authors.lastname: Taylor
authors.forename: Mark
authors.initials: M
authors.lastname: Reid
authors.forename: Jonathan
authors.initials: J
authors.lastname: Foot
authors.forename: Steven A
authors.initials: SA
authors.lastname: Raw