[Spectrum of antibodies to iron-regulated proteins in the blood sera of patients with meningococcal infection].
55 paired sera from 25 patients with meningococcal infection (meningitis, meningococcemia) were studied with the use of immunoblotting. In these sera antibodies to 15 iron-regulated proteins (IRP) were detected. In the process of the development of meningococcal infection an increase in the content of specific antibodies to IRP with molecular weights of 35 kDa (38%), 43 kDa (52%) and 47 kDa (38%) was found to occur. The induction of antibodies did not depend on the group of the infecting strain, as well as on the patient's age.
Gamzulina
L N
LN
Filatova
T N
TN
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000737:chemistry / Q000276:immunology*; D002648:Child; D006801:Humans; D015151:Immunoblotting; D033862:Iron-Binding Proteins; D008589:Meningococcal Infections / Q000097:blood*; D008970:Molecular Weight; D009345:Neisseria meningitidis / Q000276:immunology / Q000472:pathogenicity; D033902:Periplasmic Binding Proteins; D014774:Virulence
D000907:Antibodies, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D033862:Iron-Binding Proteins; D033902:Periplasmic Binding Proteins