title: Combined resection of the duodenum and pancreas for locally advanced colon cancer.
abstract: Colorectal cancer invading adjacent organs is a frequent event occurring in 5.5% to 12% of all colorectal malignancies. Colon cancer directly invading the duodenum and pancreas is rare and may require combined resection of the colon, pancreas, and duodenum, which represents a complex operation with significant morbidity and mortality rates. In this article, a case of a 41-year-old patient with a right colon cancer directly infiltrating the duodenum and head of the pancreas is presented. The patient was treated by radical combined resection of the colon, duodenum, and pancreas. Pathological examination confirmed neoplastic invasion of the adjacent organs and absence of lymph node metastasis (T4N0). The patient recovered uneventfully. Patients with colorectal cancer infiltrating adjacent organs such as the duodenum and the pancreas should be treated by radical en bloc resection of the tumor. This procedure is the preferred treatment strategy because it seems to be associated with improved overall survival rates.
authors.affiliation: Colorectal Surgery Division, Department of Gastroenterology, School of Medicine, University of São Paulo, Rua Manoel da Nóbrega 1564, 04005001 São Paulo, Brazil. rodrigo.operez@gmail.com
authors.forename: Rodrigo Oliva
authors.initials: RO
authors.lastname: Perez
authors.forename: Roger Beltrati
authors.initials: RB
authors.lastname: Coser
authors.forename: Desidério Roberto
authors.initials: DR
authors.lastname: Kiss
authors.forename: Renato Akira
authors.initials: RA
authors.lastname: Iwashita
authors.forename: José
authors.initials: J
authors.lastname: Jukemura
authors.forename: José Eduardo Monteiro
authors.initials: JE
authors.lastname: Cunha
authors.forename: Angelita
authors.initials: A
authors.lastname: Habr-Gama
mesh_terms: D000328:Adult; D003110:Colonic Neoplasms / Q000473:pathology*; D013505:Digestive System Surgical Procedures / Q000379:methods; D004379:Duodenal Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000601:surgery*