Isolation and structure revision of 10-deacetyltaxinine from the seeds of the Chinese yew, Taxus mairei.
A new taxoid was isolated from the methanol extract of the seeds of Taxus mairei. Its structures were established as 2alpha,9alpha-diacetoxy-10beta-hydroxy-5alpha-cinnamoyloxytaxa-4(20), 11-dien-13-one (l0-deacetyltaxinine) on the basis of spectral analysis including (1)H-NMR, (13)C-NMR, HMQC, HMBC, NOESY, and HR-FABMS. The structure of previously reported 10-deacetyltaxinine is 9-deacetyltaxinine.
Shi
Qing-Wen
QW
Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medicinal University, 336 Zhongshan East Road, 050017 Shijiazhuang, Hebei Province, People's Republic of China.
Li
Zuo-Ping
ZP
Zhao
Ding
D
Gu
Ji-Shun
JS
Kiyota
Hiromasa
H
D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D043823:Taxoids / Q000737:chemistry / Q000302:isolation & purification*; D020946:Taxus / Q000737:chemistry* / Q000196:embryology
C508658:10-deacetyltaxinine; D043823:Taxoids