Prospects for combinatorial chemistry in the agrosciences.
The recent progress and future prospects for the successful application of combinatorial chemistry and high throughput screening within the agrochemical lead discovery process are outlined and discussed. Solid and solution phase library synthesis technologies are reviewed and compared, and the role and importance of bioavailability, diversity and virtual screening in rational library design are detailed.
Lindell
Stephen D
SD
Bayer CropScience GmbH, Werk Höchst, G 836, D-65926 Frankfurt am Main, Germany. stephen.lindell@bayercropscience.com
Scherkenbeck
Jürgen
J
D016573:Agrochemicals / Q000737:chemistry* / Q000493:pharmacokinetics; D002622:Chemistry, Agricultural / Q000379:methods; D020650:Combinatorial Chemistry Techniques; D012995:Solubility; D013329:Structure-Activity Relationship
D016573:Agrochemicals