[Hemorrhagic dengue fever after trip to Malaysia].
A 39-year-old patient developed a disseminated rash with scattered petechiae, fever, malaise and arthralgia after a trip to Malaysia. The patient displayed increasing dengue IgG titers and borderline dengue IgM titers. Dengue fever with a hemorrhagic course is a rare condition in adult patients. Patients who have previously had dengue fever and retained non-neutralizing heterotypic antibodies are more likely to develop this complication via the phenomenon of antibody-dependent enhancement.
Hafner
C
C
Klinik und Poliklinik für Dermatologie der Universität Regensburg. christian.hafner@klinik.uni-regensburg.de
Koellner
K
K
Vogt
T
T
Landthaler
M
M
Szeimies
R-M
RM
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003716:Dengue Virus / Q000276:immunology; D003937:Diagnosis, Differential; D005858:Germany; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008296:Malaysia; D008297:Male; D019595:Severe Dengue / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D014195:Travel
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M