title: The M235T polymorphism of the angiotensinogen gene in women with polycystic ovary syndrome.
abstract: To explore the relationship between variation in AGT M235T gene and the development of the polycystic ovary syndrome (PCOS) and its sequelae, in the present study we evaluated AGT polymorphism M235T in women with PCOS and in a control group. Moreover, to detect any relationship between AGT M235T variation and intermediate and quantitative traits relevant to the pathogenesis of cardiovascular disease and PCOS, we looked for genotype-dependent differences within the subjects with PCOS.
authors.affiliation: Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padova, Padova, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Zulian
authors.forename: Paola
authors.initials: P
authors.lastname: Sartorato
authors.forename: Francesca
authors.initials: F
authors.lastname: Schiavi
authors.forename: Paolo
authors.initials: P
authors.lastname: Moghetti
authors.forename: Roberto
authors.initials: R
authors.lastname: Castello
authors.forename: Franco
authors.initials: F
authors.lastname: Mantero
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Opocher
authors.forename: Carla
authors.initials: C
authors.lastname: Scaroni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019943:Amino Acid Substitution / Q000235:genetics; D000808:Angiotensinogen / Q000235:genetics*; D016009:Chi-Square Distribution; D005260:Female; D005838:Genotype; D006801:Humans; D008715:Methionine / Q000235:genetics; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D013912:Threonine / Q000235:genetics
chemical_list: D000808:Angiotensinogen; D013912:Threonine; D008715:Methionine