title: Light alters nociceptive effects of magnetic field shielding.
abstract: Orientation and nociception (pain sensitivity) are affected by exposure to geomagnetic or low frequency (<1,000 Hz) magnetic fields of approximately the earth's field strength, i.e., 50 microT. However, these effects are often dependent on the simultaneous presence of visible light. Recently, it was shown that nociception was affected in mice acutely exposed to an electromagnetic-shielded environment in the dark (<0.05 W/m(2)) during the mid-light phase of the diurnal cycle. Here, we report for the first time that if mice are exposed to magnetic shielding in the presence of visible light (0.6 W/m(2), 400-750 nm) that most of the effects of shielding are eliminated. This simple experimental protocol may be useful in investigating the role that light plays in the detection of ambient electromagnetic fields.
authors.affiliation: Lawson Health Research Institute, Department of Nuclear Medicine, St. Joseph's Health Care, London, Ontario, Canada.
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Koziak
authors.forename: Dawn
authors.initials: D
authors.lastname: Desjardins
authors.forename: Lynn D
authors.initials: LD
authors.lastname: Keenliside
authors.forename: Alex W
authors.initials: AW
authors.lastname: Thomas
authors.forename: Frank S
authors.initials: FS
authors.lastname: Prato
mesh_terms: D000818:Animals; D003624:Darkness; D004574:Electromagnetic Fields; D008027:Light; D008280:Magnetics; D008297:Male; D051379:Mice; D010147:Pain Measurement