Nanofiber generation of hydroxyapatite and fluor-hydroxyapatite bioceramics.
In this study, we produced hydroxyapatite (HA) and fluor-hydroxyapatite (FHA) bioceramics as a novel geometrical form, the nanoscale fiber, for the biomedical applications. Based on the sol-gel precursors of the apatites, an electrospinning technique was introduced to generate nanoscale fibers. The diameter of the fibers was exploited in the range of a few micrometers to hundreds of nanometers (1.55 microm-240 nm) by means of adjusting the concentration of the sols. Through the fluoridation of apatite, the solubility of the fiber was tailored and the fluorine ions were well released from the FHA. The HA and FHA nanofibers produced in this study are considered to find potential applications in the biomaterials and tissue engineering fields.
Kim
Hae-Won
HW
Department of Dental Biomaterials, College of Dentistry, Dankook University, Cheonan, 330-714, Korea. hwkim@dku.edu
Kim
Hyoun-Ee
HE
D001672:Biocompatible Materials / Q000138:chemical synthesis; D002516:Ceramics / Q000138:chemical synthesis*; D017886:Durapatite / Q000138:chemical synthesis*; D005461:Fluorine; D006882:Hydroxyapatites / Q000138:chemical synthesis*; D036103:Nanotechnology / Q000379:methods*; D012995:Solubility
D001672:Biocompatible Materials; D006882:Hydroxyapatites; D005461:Fluorine; C028869:fluor-hydroxylapatite; D017886:Durapatite