title: Diagnosis of malignancy of prostate.
abstract: Minimal or complete lack of symptoms hinders early diagnosis of malignancy of prostate leading to undue morbidity and mortality. Therefore early detection is imperative, making use of simple and safe technique with least of expense. Five hundred consecutive patients, who reported with urinary complaints, were assessed by digital rectal examination, transabdominal suprapubic ultrasonography for prostatic volume/weight and serum assay of prostate specific antigen (PSA). Histopathological examination of prostatic biopsy of all the cases was also done. Benign prostatic hyperplasia was found in 83.6% of cases and 16.4% of the cases were of adenocarcinoma prostate of varying severity (mild, moderate and severe). It was found that volume/weight of gland and PSA levels were very good indicators of the probable diagnosis and grade of adenocarcinoma. Statistical tests taking various levels of PSA values in account also validated the results.
authors.affiliation: Department of Pathology, Gandhi Medical College, Bhopal. nkapoorn@rediffmail.com
authors.forename: Neelkamal
authors.initials: N
authors.lastname: Kapoor
authors.forename: Suneel
authors.initials: S
authors.lastname: Surange
authors.forename: Kamal Nayan
authors.initials: KN
authors.lastname: Gupta
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Husainy
authors.forename: Murtuza
authors.initials: M
authors.lastname: Faizi
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D012680:Sensitivity and Specificity
chemical_list: D017430:Prostate-Specific Antigen