[Role of neutrophils in the regulation of the reproductive tract microbiocenosis in women].
The influence of neutrophils and their secretory products on the microflora of the vaginal contents in healthy women and in women having dysbiotic processes in the vagina was studied. The secretory products of neutrophils were found to produce a bactericidal effect on the representatives of the opportunistic bacteria, this effect being less pronounced with respect to lactic-acid bacteria. The established effect of neutrophils on bacteria is regarded as one of the mechanisms of microbiocenosis formation, ensuring colonization resistance.
Dolgushin
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Andreeva
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IuS
D015169:Colony Count, Microbial; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D009504:Neutrophils / Q000378:metabolism; D014621:Vagina / Q000276:immunology* / Q000382:microbiology*; D016585:Vaginosis, Bacterial / Q000276:immunology* / Q000382:microbiology*; D015003:Yeasts / Q000302:isolation & purification