Markers of cardiac ischemia and inflammation.
Because biomarkers of myocardial necrosis only become positive in the setting of myocardial necrosis and disruption of cellular integrity, the diagnosis of myocardial infarction can only be made in retrospect. Ideally, one would like to identify patients at risk for complications before myocardial necrosis occurs. Insights into the pathophysiology of atherothrombosis have allowed development of novel markers to detect not only early ischemia without myocyte death but also early indicators of coronary inflammation inpatients who have preclinical atherosclerosis.
Wang
Tracy Y
TY
Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA.
AlJaroudi
Wael A
WA
Newby
L Kristin
LK
D015415:Biomarkers / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood / Q000175:diagnosis*; D042241:Early Diagnosis; D006801:Humans; D017202:Myocardial Ischemia / Q000097:blood*; D009205:Myocarditis / Q000097:blood* / Q000175:diagnosis*
D015415:Biomarkers