Exercise tolerance and hyperinsulinemia in cardiac syndrome X.
The aim of the study was to evaluate the relationship between exercise tolerance, glucose and insulin levels and biochemical parameters related to endothelial function [endothelin-1 (ET-1), nitrite/nitrate (NOx)] in patients with cardiological syndrome X in comparison with healthy volunteers. The decrease of NOx level and NOx / ET-1 ratio suggests that endothelial dysfunction is present in cardiological syndrome X. Exercise tolerance correlated positively with NOx and negatively with insulin concentrations.
Kolasilska-Kloch
Władysława
W
II Klinika Kardiologii Instytutu Kardiologii, Collegium Medicum Uniwersytetu Jagiellońskiego.
Leśniak
Wiktoria
W
Leszczyńska-Gołabek
Iwona
I
Kieć-Wilk
Beata
B
Kloch
Małgorzata
M
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D019332:Endothelin-1 / Q000097:blood; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology*; D017079:Exercise Tolerance; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000503:physiopathology*; D007328:Insulin / Q000097:blood; D008297:Male; D017566:Microvascular Angina / Q000097:blood / Q000503:physiopathology*; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood
D015415:Biomarkers; D001786:Blood Glucose; D019332:Endothelin-1; D007328:Insulin; D009569:Nitric Oxide