A rare case of glioblastoma multiforme.
A male, 39 years, entered rapidly in coma, was admitted in the Neurological Hospital Brasov and deceased after 4 hrs in hospital. At necropsy, macroscopic appearances of the cut surface showing unique tumour mass in all brain from frontal lobe to cerebellum, with extensive cortical invasion. The tumor has a variable coloration, a yellowish central necrosis and cysts containing turbid fluid. Histopathological aspect is extremely variable with regional heterogeneity: striking cellular pleomorphism with a lack of cell processes, anaplastic glial cells, and some multinucleated giant cells, large necrotic areas with pseudo-palisading of surrounding tumor cells and microvascular proliferation, as glomeruloid tufts.
Radu
I
I
Department of Histology, Faculty of Medicine, University of "Transilvania", Braşov. raduic@k.ro
Nicola
A
A
Micu
Daniela
D
Minea
D
D
D000328:Adult; D001921:Brain / Q000473:pathology*; D017809:Fatal Outcome; D005909:Glioblastoma / Q000473:pathology*; D006801:Humans; D008297:Male