title: [Perfusion MR imaging for initial diagnosis and follow-up of brain tumors].
abstract: OBJECTIVE
  To discuss the pertinency of perfusion MR imaging for initial diagnosis and follow up of brain tumors.
  
  
  METHODS
  Dynamic susceptibility contrast MR imaging was applied. Images were thus obtained with intensities proportional to the cerebral blood volume (CBV). Relative cerebral blood volume (rCBV) maps were then generated by normalizing the signal intensities with respect to measurements made in healthy tissue.
  
  
  RESULTS
  The method provided interesting data for establishing the differential diagnosis between different kinds of lesions, in particular between lymphoma and pilocytic astrocytoma, and for grading gliomas.
  
  
  CONCLUSIONS
  Limits of the approach are discussed, in particular with respect to quantification aspects and interpretation of the results. The approach could be particularly useful for grading oligodendrogliomas, for which histological diagnosis on biopsy is sometimes difficult.
authors.affiliation: Unité IRM et Service de NeuroRadiologie, CHU, Grenoble. JFLeBas@chu-grenoble.fr
authors.forename: J-F
authors.initials: JF
authors.lastname: Le Bas
authors.forename: S
authors.initials: S
authors.lastname: Grand
authors.forename: S
authors.initials: S
authors.lastname: Kremer
authors.forename: I
authors.initials: I
authors.lastname: Tropres
authors.forename: Z
authors.initials: Z
authors.lastname: Jiang
authors.forename: A
authors.initials: A
authors.lastname: Krainik
authors.forename: C
authors.initials: C
authors.lastname: Remy
authors.forename: F
authors.initials: F
authors.lastname: Berger
authors.forename: A-L
authors.initials: AL
authors.lastname: Benabid
mesh_terms: D001254:Astrocytoma / Q000098:blood supply / Q000175:diagnosis / Q000601:surgery; D001706:Biopsy; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000601:surgery; D002560:Cerebrovascular Circulation; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005910:Glioma / Q000098:blood supply / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000098:blood supply / Q000175:diagnosis / Q000601:surgery; D008579:Meningioma / Q000098:blood supply / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009367:Neoplasm Staging; D009837:Oligodendroglioma / Q000175:diagnosis* / Q000601:surgery; D015899:Tomography, Emission-Computed, Single-Photon