title: [Physical performance and thermoregulatory study of subjects with sickle cell trait during a sub-maximal exercise].
abstract: The sickle cell trait is a genetic abnormality of red blood cells. It is due to the mutation of a parental gene, which rest Its to the substitution of glutamic acid by valin on beta globin chain of haemoglobin. The possibility for sickle cell trait carriers (SCT) to present any disturbance during predominantly anaerobic and aerobic exercises is unclear. Ten (10) subjects with sickle cell trait and 10 subjects control were studied during exercise test on cycloergometer. They were all students of the National Institute of Popular Education and Sport of Dakar. The mean of environmental temperature was 26 degrees C and humidity was 60 to 80%. After haematological analysis, a submaximal muscular exercise for one hour with 75% of maximal heart rate was done. We have determined heart rate, blood pressure, rectal and skin temperature during exercise. Haematological parameters shown any significant difference between the two groups. No significant difference was found in cardiocirculatory variables during maximal exercise in cycloergometer between control group and sickle cell trait group. The two groups have done submaximal exercise during 1 hour without particular difficulty. We have not observed a significant difference between the two groups in cardiovascular variables, rectal and skin temperature during exercise, and after 3 minutes of rest. These results show that subjects with SCT have physical capacity comparable with control subjects during a sub maximal exercise for 1 hour. We can assure that subjects with SCT in our country may participate in sports competition, as well as normal subjects (HbAA).
authors.affiliation: Laboratoire de physiologie, Faculté de Médecine et Pharmacie, UCAD Dakar. asamb@ucad.sn
authors.forename: A
authors.initials: A
authors.lastname: Samb
authors.forename: M O
authors.initials: MO
authors.lastname: Kane
authors.forename: A
authors.initials: A
authors.lastname: Ba
authors.forename: M
authors.initials: M
authors.lastname: Gadji
authors.forename: D
authors.initials: D
authors.lastname: Seck
authors.forename: L
authors.initials: L
authors.lastname: Badji
authors.forename: F B
authors.initials: FB
authors.lastname: Sarr
authors.forename: M
authors.initials: M
authors.lastname: Sarr
authors.forename: S A
authors.initials: SA
authors.lastname: Dieng
authors.forename: E M N
authors.initials: EM
authors.lastname: Diakhate
authors.forename: L
authors.initials: L
authors.lastname: Gueye
authors.forename: L
authors.initials: L
authors.lastname: Diakhate
authors.forename: F
authors.initials: F
authors.lastname: Cisse
authors.forename: J P
authors.initials: JP
authors.lastname: Martineaud
mesh_terms: D001794:Blood Pressure; D001831:Body Temperature; D001833:Body Temperature Regulation; D002320:Cardiovascular Physiological Phenomena; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006339:Heart Rate; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D010809:Physical Fitness; D012016:Reference Values; D012146:Rest; D012805:Sickle Cell Trait / Q000503:physiopathology*; D013177:Sports
chemical_list: D006451:Hemoglobin, Sickle