title: Immunoglobulin G kappa [IgG kappa] and IgG lambda paraproteinemia in a child with AIDS and response to highly active antiretroviral therapy.
abstract: We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(kappa)] and IgG lambda [IgG(lambda)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of controlling B-cell activation.
authors.affiliation: Section of Allergy & Immunology, Texas Children's Hospital and Baylor College of Medicine, 6621 Fannin Street (MC; FC330.01), Houston, Texas 77030, USA. fodabasi@hotmail.com
authors.forename: Filiz Odabasi
authors.initials: FO
authors.lastname: Seeborg
authors.forename: Hannah
authors.initials: H
authors.lastname: Gay
authors.forename: Lorenz M
authors.initials: LM
authors.lastname: Schmiege
authors.forename: David
authors.initials: D
authors.lastname: Bernard
authors.forename: William T
authors.initials: WT
authors.lastname: Shearer
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000188:drug therapy* / Q000276:immunology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D007146:Immunoglobulin lambda-Chains / Q000097:blood*; D008297:Male; D010265:Paraproteinemias / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains