Adolescent smoking in pregnancy and birth outcomes.
BACKGROUND
Cigarette smoking amongst pregnant adolescents is a preventable risk factor associated with low birthweight (<2,500 g), preterm birth (<37 weeks) and infant mortality. The aim of this study was to compare birth outcomes of adolescents who smoke during pregnancy with those who do not and to construct their birthweight-for-gestational-age curves.


METHODS
A retrospective cohort analysis of 534 adolescents (<or=19 years) and 8972 adults who delivered singleton births between 1998-2003 at the Liverpool Women's Hospital.


RESULTS
Adolescent pregnancy occurred in 5.6% of deliveries. Mean age of adolescents was 18.1 years (SD = 1.0) and 46.2% smoked during pregnancy including 83.5% light smokers (<10 cigarettes daily). Babies born to adolescent smokers were significantly lighter by -170 g (P = 0.005). The prevalence of low birthweight was almost double in adolescents who smoked (12.1% versus 6.8%, RR = 1.7; CI = 1.0-3.0), and their mean Apgar scores at 5 min were lower (<0.05). A higher prevalence of preterm birth (P < 0.05) and maternal anaemia (P < 0.01) occurred amongst adolescent smokers. Adolescents smoking >10 cigarettes daily had babies with larger birthweight reduction (P = 0.001).


CONCLUSIONS
Almost half of all adolescents smoked during their pregnancy. Birthweight-for-gestational-age curves of smoking adolescents showed a marked fall-off in weight from 36 weeks of gestation, and at least 10% of adolescent smokers showed fetal growth restriction from before 32 weeks of gestation.
Delpisheh
Ali
A
Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, UK.
Attia
Eman
E
Drammond
Sandra
S
Brabin
Bernard J
BJ
D000293:Adolescent; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology*; D006113:United Kingdom / Q000453:epidemiology