title: Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?
abstract: OBJECTIVE
  To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM).
  
  
  METHODS
  Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM.
  
  
  RESULTS
  There was a significant reduction in sperm disomy in all six men. This coincided with TCM treatment.
  
  
  CONCLUSIONS
  This is the first study reporting a significant reduction in sperm disomy in men over a given time course. The fact that this coincided with TCM treatment is intriguing but no conclusions can be drawn from this until placebo-controlled clinical trials are implemented.
authors.affiliation: Department of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.
authors.forename: Helen G
authors.initials: HG
authors.lastname: Tempest
authors.forename: Sheryl T
authors.initials: ST
authors.lastname: Homa
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Zhai
authors.forename: Darren K
authors.initials: DK
authors.lastname: Griffin
mesh_terms: D000328:Adult; D000782:Aneuploidy; D041321:Chromosomes, Human, X / Q000235:genetics; D041322:Chromosomes, Human, Y / Q000235:genetics; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007248:Infertility, Male / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology*; D008297:Male; D008516:Medicine, Chinese Traditional; D013094:Spermatozoa / Q000473:pathology* / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal