Adult onset Still's disease as a cause of acute severe mitral and aortic regurgitation.
Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly, and serositis. Pericarditis is the most common cardiac manifestation of AOSD and occurs in approximately 30% of cases. A simultaneous occurrence of rapidly progressive bi-valvular regurgitation associated with AOSD has not been previously described. We report a case of a 55-year old woman who underwent mitral valve replacement and Bentall's operation due to acute severe mitral and aortic regurgitation associated with AOSD.
Lee
Jae Seung
JS
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Do
Il No
IN
Kang
Deok Hyun
DH
Joo
Seok Jung
SJ
Yoo
Bin
B
Moon
Hee Bom
HB
Lee
Chang-Keun
CK
D000208:Acute Disease; D000367:Age Factors; D001022:Aortic Valve Insufficiency / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000473:pathology; D016706:Still's Disease, Adult-Onset / Q000150:complications*; D013997:Time Factors