Benzotriazole-assisted thioacylation.
[Chemical reaction: See text] Benzotriazole reagents for thioacylation (RCSBt), thiocarbamoylation (RR'NCSBt), aryl/alkoxythioacylation (ROCSBt), and aryl/alkylthiothioacylation (RSCSBt) are synthesized, and their utility is assessed by syntheses of representative heteroaryl thioureas 3a-g, thioamides 15a-s, thionoesters 16a-h, thiocarbamates 17a-e, dithiocarbamates 18a-d, thiocarbonates 19a-c, and dithiocarbonates 20a-c.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. Katritzky@chem.ufl.edu
Witek
Rachel M
RM
Rodriguez-Garcia
Valerie
V
Mohapatra
Prabhu P
PP
Rogers
James W
JW
Cusido
Janet
J
Abdel-Fattah
Ashraf A A
AA
Steel
Peter J
PJ