Chronic granulomatous disease presenting with eosinophilic inflammation.
Chronic granulomatous disease (CGD), a rare immunodeficiency, typically presents with recurrent infections caused by catalase-positive organisms. We report 2 patients with CGD who presented with eosinophilic inflammatory conditions recognized before the diagnosis of CGD. Both patients had significant urologic disease. Physicians should be aware of the association of CGD with eosinophilic inflammatory conditions.
Jaggi
Preeti
P
Division of Infectious Disease, Department of Pediatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA. pjaggi@childrensmemorial.org
Freeman
Alexandra F
AF
Katz
Ben Z
BZ
D042441:Achromobacter denitrificans / Q000201:enzymology / Q000302:isolation & purification*; D001228:Aspergillosis / Q000150:complications / Q000175:diagnosis; D001230:Aspergillus / Q000201:enzymology / Q000302:isolation & purification; D002374:Catalase / Q000378:metabolism*; D002675:Child, Preschool; D004804:Eosinophils / Q000276:immunology; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis; D006105:Granulomatous Disease, Chronic / Q000276:immunology* / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007249:Inflammation / Q000276:immunology / Q000382:microbiology*; D008297:Male
D002374:Catalase