Births using sperm retrieved via immediate microdissection of a solitary testis with cancer.
OBJECTIVE
To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.


METHODS
Prospective clinical study of azoospermic men with testis cancer in a solitary testis.


METHODS
Infertility patients in an academic environment.


METHODS
Azoospermic men with previous history of orchiectomy and testis cancer in a remaining solitary testis.


METHODS
Viable sperm were retrieved by immediate microdissection of paratumor testicular tissue from orchiectomy specimen.


METHODS
Live births were achieved using sperm from immediate microdissection of orchiectomy specimen with testis cancer.


CONCLUSIONS
Azoospermic men with cancer in a solitary testis have potential for fertility.
Choi
Benjamin B
BB
Department of Urology, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York, USA.
Goldstein
Marc
M
Moomjy
Maureen
M
Palermo
Gianpiero
G
Rosenwaks
Zev
Z
Schlegel
Peter N
PN
D000328:Adult; D005260:Female; D006801:Humans; D050498:Live Birth; D008297:Male; D042282:Microdissection / Q000379:methods*; D011247:Pregnancy; D013094:Spermatozoa / Q000166:cytology*; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery; D013737:Testis / Q000473:pathology* / Q000601:surgery