title: [Ropivacaine-induced grand mal convulsion after obturator nerve block].
abstract: We describe a patient to whom ropivacaine 150 mg had been administered during obturator nerve blockade and developed grand mal convulsions because of inadvertent i.v. injection. Venous blood samples were taken 15, 32 and 52 min after the convulsion. The measured total plasma concentrations of ropivacaine were 4.5, 3.5 and 2.9 microg x ml(-1) respectively. The peak plasma concentration at the time of the inadvertent i.v. injection was estimated to be 6.6 microg x ml(-1). The patient recovered uneventfully.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Jichi Medical School, Tochigi 329 0498.
authors.forename: Mizue
authors.initials: M
authors.lastname: Takeuchi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Hirabayashi
authors.forename: Kunihisa
authors.initials: K
authors.lastname: Hotta
authors.forename: Soichiroh
authors.initials: S
authors.lastname: Inoue
authors.forename: Norimasa
authors.initials: N
authors.lastname: Seo
mesh_terms: D000328:Adult; D000577:Amides / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects*; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009407:Nerve Block / Q000009:adverse effects*; D009776:Obturator Nerve; D000077212:Ropivacaine
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine