[Spermatogenesis arrest].
Spermatogenesis arrest is a complex process of interruption in the differentiation of germinal cells of specific cellular type, which elicits an altered spermatozoa formation. In contrast, hypospermatogenesis is defined as a decrease in number of germ cells and its proportion. Factors identified intervening upon spermatogenesis arrest are: genetic, hormonal, growth factors, interaction between Sertoli and germ cells and ectoplasmic specialization integrity of spermatozoa. In addition, environmental toxic effects have shown to exert subletal and letal cellular damage with gene disruption. Hence in this work we review sperm physiology along with etiologic elements associated to spermatogenesis arrest delineating the most appropriate conduct for diagnosis and treatment.
Málaga Correa
Yanet R
YR
Departamento de Biología de la Reproducción Humana, Dirección de Investigación y Enseñanza, Hospital Juárez de México, SS México, DF.
Ortiz Núñez
Damaris A
DA
Hernández Marín
Imelda
I
Tovar
José María
JM
Ayala Ruíz
Aquiles
A
D006801:Humans; D008297:Male; D009845:Oligospermia / Q000188:drug therapy / Q000209:etiology*; D027724:Reproductive Techniques, Assisted; D013091:Spermatogenesis / Q000502:physiology