A new serratane-type triterpene from Lycopodium phlegmaria.
A new serratane-type triterpene, lycophlegmarin (1), has been isolated from Lycopodium phlegmaria L. Four known related triterpenoids were also found from the title plant. The structure of the new compound was elucidated on the basis of detailed spectroscopic analysis and chemical method. Lycophlegmarin exhibited modest growth-inhibitory activity in vitro against human hepatoma cells BEL 7402.
Shi
Hao
H
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Zhangjiang Hi-tech Park, Shanghai 201203, P R China.
Li
Zhen-Yu
ZY
Guo
Yue-Wei
YW
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D032502:Lycopodium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D014315:Triterpenes; C508405:lycophlegmarin