title: [Comparative studies on pharmacological effects of the main chemical constituents of Peucedanum praeruptorum from He'nan and Jiangxi].
abstract: OBJECTIVE
  To compare the pharmacological effect of the main coumarin constituents of Peucedanum praeruptorum from Jiangxi and He'nan.
  
  
  METHODS
  The constituents were isolated by column chromatography on silica gel and ODS and identified by NMR and MS spectroscopic methods. The antitussive, expectorant and anti-inflammatory effects of main coumarin constituents of P. praeruptorum observed in the present study.
  
  
  RESULTS
  The main constituents of P. praeruptorum from both Jiangxi and He'nan showed the significant antitussive and anti-inflammatory effects without obviously expectorant effect.
  
  
  CONCLUSIONS
  The pharmacological effects of the main coumarin constituents of Qian-hu from Jiangxi and He'nan are similar.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
authors.forename: Cun
authors.initials: C
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.forename: Yong-qing
authors.initials: YQ
authors.lastname: Xiao
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000302:isolation & purification / Q000494:pharmacology*; D000996:Antitussive Agents / Q000302:isolation & purification / Q000494:pharmacology*; D019661:Apiaceae / Q000737:chemistry*; D002681:China; D003374:Coumarins / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005260:Female; D008297:Male; D051379:Mice
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000996:Antitussive Agents; D003374:Coumarins; D004365:Drugs, Chinese Herbal; C030123:coumarin