Detecting biological warfare agents.
We developed a fiber-optic, microsphere-based, high-density array composed of 18 species-specific probe microsensors to identify biological warfare agents. We simultaneously identified multiple biological warfare agents in environmental samples by looking at specific probe responses after hybridization and response patterns of the multiplexed array.
Song
Linan
L
Tufts University, Medford, Massachusetts, USA.
Ahn
Soohyoun
S
Walt
David R
DR
D001419:Bacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D001694:Biological Warfare / Q000379:methods / Q000517:prevention & control*; D015342:DNA Probes; D005336:Fiber Optic Technology / Q000295:instrumentation / Q000379:methods; D006801:Humans; D008863:Microspheres; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation / Q000379:methods; D055100:Optical Fibers; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D013045:Species Specificity; D014616:Vaccinia virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
D015342:DNA Probes