[Quality of life in patients with chronic rhinosinusitis: validation of the Sino-Nasal Outcome Test-20 German Adapted Version].
BACKGROUND
No validated German instrument for measuring health-related quality of life (QOL) in patients with chronic rhinosinusitis (CRS) has been available to date.


METHODS
The Sino-Nasal Outcome Test-20 German Adapted Version (SNOT-20 GAV) is a translated and adapted version of SNOT-20. To validate this instrument, we evaluated its reliability, validity and sensitivity. SNOT-20 GAV was completed by 163, 123, and 82 patients at the initial visit and at 3 months and 1 year after treatment commencement, respectively.


RESULTS
Cronbach's alpha indicated good internal consistency. Test-retest scores in 38 patients were highly correlated. Discrimination validity was demonstrated by a comparison with healthy controls. Sensitivity to change showed medium to large effects.


CONCLUSIONS
SNOT-20 GAV is the first reliable, validated and sensitive German instrument for measuring health-related QOL in patients with CRS.
Baumann
I
I
Universitäts-HNO-Klinik Heidelberg. ingo.baumann@med.uni-heidelberg.de
Blumenstock
G
G
DeMaddalena
H
H
Piccirillo
J F
JF
Plinkert
P K
PK
D000328:Adult; D002908:Chronic Disease; D005858:Germany / Q000453:epidemiology; D006801:Humans; D010043:Outcome and Process Assessment, Health Care / Q000379:methods* / Q000706:statistics & numerical data; D011785:Quality Assurance, Health Care / Q000379:methods*; D011788:Quality of Life; D015203:Reproducibility of Results; D012220:Rhinitis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D012680:Sensitivity and Specificity; D012852:Sinusitis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome