title: A comparison of three SPRITE techniques for the quantitative 3D imaging of the 23Na spin density on a 4T whole-body machine.
abstract: Sodium density maps acquired with three SPRITE-based methods have been compared in terms of the resulting quantitative information as well as image quality and acquisition times. Consideration of factors relevant for the clinical implementation of SPRITE shows that the Conical-SPRITE variant is preferred because of a 20-fold reduction in acquisition time, slightly improved image quality, and no loss of quantitative information. The acquisition of a 3D data set (32x32x16; FOV=256x256x160 mm) for the quantitative determination of sodium density is demonstrated. In vivo Conical-SPRITE 23Na images of the brain of a healthy volunteer were acquired in 30 min with a resolution of 7.5x7.5x7.5 mm and a signal-to-noise ratio of 23 in cerebrospinal fluid and 17 in brain tissue.
authors.affiliation: Institute of Medicine, Research Centre Jülich, 52425 Jülich, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Romanzetti
authors.forename: M
authors.initials: M
authors.lastname: Halse
authors.forename: J
authors.initials: J
authors.lastname: Kaffanke
authors.forename: K
authors.initials: K
authors.lastname: Zilles
authors.forename: B J
authors.initials: BJ
authors.lastname: Balcom
authors.forename: N J
authors.initials: NJ
authors.lastname: Shah
mesh_terms: D001921:Brain / Q000378:metabolism*; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012964:Sodium / Q000378:metabolism*; D012975:Sodium Isotopes
chemical_list: D012975:Sodium Isotopes; D012964:Sodium