title: [Survey of level of house dust mite specific IgE and interleukin-4 pre and post desensitization therapy].
abstract: OBJECTIVE
  Survey the house dust mite specific IgE and interleukin-4's (IL-4) role in the desensitization therapy.
  
  
  METHODS
  Evaluate the effects of desensitization therapy. Determine the serum level of dl and IL-4 pre and post desensitization therapy, and then test of significance and correlative analysis were made.
  
  
  RESULTS
  There's significant difference between the levels of IL-4 pre and post therapy, and it has positive correlation with the symptom score. But there's no significant difference between the levels of dl pre and post therapy.
  
  
  CONCLUSIONS
  IL-4 plays a very important role in both of the pathogenesis of allergic rhinitis and the desensitization therapy. But specific IgE may just has the same effect in the pathogenesis.
authors.affiliation: Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. wangzhxl@yahoo.com.cn
authors.forename: Zhongxi
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D016022:Case-Control Studies; D003888:Desensitization, Immunologic; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D015847:Interleukin-4 / Q000276:immunology / Q000378:metabolism*; D008875:Middle Aged; D039981:Pyroglyphidae / Q000276:immunology*; D012221:Rhinitis, Allergic, Perennial / Q000097:blood* / Q000628:therapy; D055815:Young Adult
chemical_list: C508598:IL4 protein, human; D015847:Interleukin-4; D007073:Immunoglobulin E