title: Unusual duodenal presentation of leishmaniasis.
abstract: This case report describes an atypical case of duodenal leishmaniasis in an elderly patient not infected with human immunodeficiency virus. Investigation of this 84 year old woman with a constitutional syndrome and dysphagia revealed anaemia of chronic disorder, a high erythrocyte sedimentation rate, and polyclonal hypergammaglobulinaemia. Abdominal ultrasonography revealed thickening of the stomach wall, which was seen to be inflamed during gastroscopy. Duodenal histology revealed numerous leishmania amastigotes within macrophages. This was confirmed by bone marrow biopsy and leishmania serology. This case report stresses the importance of atypical symptoms and the unusual location of visceral leishmaniasis, not only in immunodepressed patients, but also in elderly immunocompetent patients.
authors.affiliation: Geriatrics Department, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain. alvereznebreda@yahoo.es
authors.forename: M L
authors.initials: ML
authors.lastname: Alvarez-Nebreda
authors.forename: E
authors.initials: E
authors.lastname: Alvarez-Fernández
authors.forename: S
authors.initials: S
authors.lastname: Rada
authors.forename: F
authors.initials: F
authors.lastname: Brañas
authors.forename: E
authors.initials: E
authors.lastname: Marañón
authors.forename: M T
authors.initials: MT
authors.lastname: Vidán
authors.forename: J A
authors.initials: JA
authors.lastname: Serra-Rexach
mesh_terms: D000369:Aged, 80 and over; D004378:Duodenal Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000473:pathology*; D007898:Leishmaniasis, Visceral / Q000473:pathology*