Eye on regeneration.
Lens regeneration in newts is a remarkable process, whereby a lost tissue is replaced by transdifferentiation of adult tissues that only a few organisms possess. In this review, we will touch on the approaches being used to study this phenomenon, recent advances in the field of lens regeneration, similarities and differences between development and regeneration, as well as the potential role stem cells may play in understanding this process.
Call
Mindy K
MK
University of Dayton, Ohio 45469, USA.
Grogg
Matthew W
MW
Tsonis
Panagiotis A
PA
D000818:Animals; D047108:Embryonic Development / Q000235:genetics / Q000502:physiology; D007908:Lens, Crystalline / Q000166:cytology / Q000254:growth & development / Q000502:physiology*; D012038:Regeneration / Q000502:physiology*; D012455:Salamandridae / Q000502:physiology; D013234:Stem Cells / Q000502:physiology