title: [Changes of edema associated with I-125 prostate brachytherapy].
abstract: We have been performing TRUS-guided transperineal prostate brachytherapy with I-125 for prostate-confined adenocarcinoma since October 2003. We examined prostate volume using CT scanning on Day 1, Day 15, and Day 30 in the initial 15 patients, and investigated time-dependent changes of edema associated with I-125 prostate brachytherapy. Prostate volume had increased to 173% of the average on the first day after implantation. Improvements in the swelling of the prostate showed decreases in 30% in the first 2 weeks (Days 1-15) and 12% in the second 2 weeks (Days 15-30). V100 and D 90% showed statistically significant increases of 5.5% and 8.4% in the first 2 weeks after implantation and 2.3% and 5.2% in the second 2 weeks (Days 15-30). We considered one month a suitable time at which to calculate post-planning because V100 and D 90% changed little statistically.
authors.affiliation: Division of Radiation oncology, Department of Radiology, Jikei University School of Medicine.
authors.forename: Manabu
authors.initials: M
authors.lastname: Aoki
authors.forename: Kenta
authors.initials: K
authors.lastname: Miki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Sayako
authors.initials: S
authors.lastname: Takagi
authors.forename: Ichirou
authors.initials: I
authors.lastname: Fukuda
authors.forename: Chikara
authors.initials: C
authors.lastname: Honda
authors.forename: Masao
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Shin
authors.initials: S
authors.lastname: Egawa
authors.forename: Chihiro
authors.initials: C
authors.lastname: Kanehira
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D004487:Edema / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011469:Prostatic Diseases / Q000209:etiology / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted
chemical_list: D007457:Iodine Radioisotopes