title: [Malignant struma ovarii: a case report].
abstract: Malignant transformation of struma ovarii is exceptional (less than 1%). The histolological diagnosis of malignancy is difficult especially in the well differentiated forms. Immunohistochemistry is highly contributive in the anaplastic forms. The prognosis is relatively favorable except for the metastatic and undifferentiated forms. We report a case of malignant struma ovarii with metastasis observed in a 65-year-old woman who died rapidly from her disease. In light of this observation, we discuss the diagnositic, management and outcome features of these particular tumors.
authors.affiliation: Laboratoire d'Anatomie et de Cytologie Pathologiques, CHU Habib Bourguiba, Sfax, Tunisie. akabdelmajid@yahoo.fr
authors.forename: S Krichen
authors.initials: SK
authors.lastname: Makni
authors.forename: I
authors.initials: I
authors.lastname: Bahri
authors.forename: S
authors.initials: S
authors.lastname: Ellouze
authors.forename: H
authors.initials: H
authors.lastname: Mnif
authors.forename: L
authors.initials: L
authors.lastname: Ayadi
authors.forename: M
authors.initials: M
authors.lastname: Ghariani
authors.forename: H
authors.initials: H
authors.lastname: Khmiri
authors.forename: T
authors.initials: T
authors.lastname: Boudawara
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D053552:Keratin-7; D007633:Keratins / Q000032:analysis; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011878:Radiotherapy; D013330:Struma Ovarii / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D013954:Thyroglobulin / Q000032:analysis
chemical_list: D000970:Antineoplastic Agents; C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins; D013954:Thyroglobulin