title: Hypertrophic osteoarthropathy and intrathoracic Hodgkin's disease in children.
abstract: BACKGROUND
  Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by clubbing of the fingers and toes, periosteal new bone formation of the long bones and polyarthritis.
  
  
  METHODS
  In this report, two children with intrathoracic Hodgkin's disease and HOA are presented.
  
  
  CONCLUSIONS
  Intrathoracic neoplasms are one of the major causes of HOA in adults; however HOA is rarely associated with intrathoracic malignancies in children. HOA associated with intrathoracic Hodgkin's disease is even more rare, but should be kept in mind.
authors.affiliation: Istanbul University, Oncology Institute, Division of Pediatric Oncology, Turkey. rejinkebudi@hotmail.com
authors.forename: Rejin
authors.initials: R
authors.lastname: Kebudi
authors.forename: Inci
authors.initials: I
authors.lastname: Ayan
authors.forename: Omer
authors.initials: O
authors.lastname: Görgün
authors.forename: Fulya Yaman
authors.initials: FY
authors.lastname: Ağaoğlu
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Dizdar
authors.forename: Emin
authors.initials: E
authors.lastname: Darendeliler
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D044963:Biopsy, Fine-Needle; D002648:Child; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D010257:Paraneoplastic Syndromes; D016896:Treatment Outcome