title: MRI study of corpus callosum in children and adolescents with bipolar disorder.
abstract: This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.
authors.affiliation: MOOD-CNS Program (Mood Disorders Clinical Neurosciences Program), Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229-3900, USA.
authors.forename: A Sibel
authors.initials: AS
authors.lastname: Yasar
authors.forename: E Serap
authors.initials: ES
authors.lastname: Monkul
authors.forename: Roberto B
authors.initials: RB
authors.lastname: Sassi
authors.forename: David
authors.initials: D
authors.lastname: Axelson
authors.forename: Paolo
authors.initials: P
authors.lastname: Brambilla
authors.forename: Mark A
authors.initials: MA
authors.lastname: Nicoletti
authors.forename: John P
authors.initials: JP
authors.lastname: Hatch
authors.forename: Matcheri
authors.initials: M
authors.lastname: Keshavan
authors.forename: Neal
authors.initials: N
authors.lastname: Ryan
authors.forename: Boris
authors.initials: B
authors.lastname: Birmaher
authors.forename: Jair C
authors.initials: JC
authors.lastname: Soares
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis*; D002648:Child; D003337:Corpus Callosum / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male