title: [Klinefelter's syndrome diagnosed three years after surgery for mediastinal teratoma].
abstract: BACKGROUND
  The association between some types of tumor and Klinefelter's syndrome (KS) is often missed and diagnosis of the latter delayed, as in this case report.
  
  
  METHODS
  We present the case of a 20 year-old patient for whom KS was not diagnosed until three years after thoracic surgery for a mediastinal teratoma.
  
  
  CONCLUSIONS
  The association between KS and mediastinal germ-cell tumors is not coincidental; it illustrates the relation between aneuploidy and oncogenesis. In a young adult male, palpation of the scrotum to look for microorchidism is justified when these tumors are diagnosed because 25% occur in patients with KS.
authors.affiliation: Service de pneumologie, HIA Percy, Clamart (92). j.margery@wanadoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Margery
authors.forename: J P
authors.initials: JP
authors.lastname: Le Berre
authors.forename: C
authors.initials: C
authors.lastname: Bredin
authors.forename: L
authors.initials: L
authors.lastname: Bordier
authors.forename: O
authors.initials: O
authors.lastname: Dupuy
authors.forename: H
authors.initials: H
authors.lastname: Mayaudon
authors.forename: J
authors.initials: J
authors.lastname: Guigay
authors.forename: B
authors.initials: B
authors.lastname: Bauducea
mesh_terms: D000328:Adult; D000728:Androgens / Q000008:administration & dosage / Q000627:therapeutic use; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007273:Injections, Intramuscular; D007713:Klinefelter Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D013724:Teratoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D013739:Testosterone / Q000097:blood; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000728:Androgens; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone