title: Formal syntheses of (+/-)-pinnaic acid and (+/-)-halichlorine.
abstract: [chemical reaction: see text]. Concise formal syntheses of marine alkaloids (+/-)-pinnaic acid (1) and (+/-)-halichlorine (2) have been accomplished from a common intermediate. The syntheses illustrate the utility of selective olefin cross metathesis methodologies for the elaboration of advanced synthetic intermediates in complex molecule synthesis.
authors.affiliation: Department of Chemistry and Biochemistry, The University of Texas, Austin, Texas 78712, USA.
authors.forename: Rodrigo B
authors.initials: RB
authors.lastname: Andrade
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Martin
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D000818:Animals; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D013141:Spiro Compounds; C412666:halichlorine; C412665:pinnaic acid