title: Effect of statin use in patients with acute coronary syndromes and a serum low-density lipoprotein<or=80 mg/dl.
abstract: We identified 155 patients who were admitted with an acute coronary syndrome and a low-density lipoprotein cholesterol level<or=80 mg/dl and were not on statin therapy at hospital admission. The relation between statin therapy at discharge and clinical outcome was evaluated in these patients. Compared with patients who were not discharged on statins, those who were had a lower incidence of death, reinfarction, or stroke at 6 months (29.0% vs 9.5%, p=0.005). These results suggest that patients who have an acute coronary syndrome and a low-density lipoprotein cholesterol level<or=80 mg/dl in the absence of statin therapy may benefit from such therapy at discharge.
authors.affiliation: Department of Internal Medicine, Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA. hsianshi@umich.edu
authors.forename: Thomas T
authors.initials: TT
authors.lastname: Tsai
authors.forename: Brahmajee K
authors.initials: BK
authors.lastname: Nallamothu
authors.forename: Debabrata
authors.initials: D
authors.lastname: Mukherjee
authors.forename: Melvyn
authors.initials: M
authors.lastname: Rubenfire
authors.forename: Jianming
authors.initials: J
authors.lastname: Fang
authors.forename: Paul
authors.initials: P
authors.lastname: Chan
authors.forename: Eva
authors.initials: E
authors.lastname: Kline-Rogers
authors.forename: Amisha
authors.initials: A
authors.lastname: Patel
authors.forename: David F
authors.initials: DF
authors.lastname: Armstrong
authors.forename: Kim A
authors.initials: KA
authors.lastname: Eagle
authors.forename: A D
authors.initials: AD
authors.lastname: Goldberg
mesh_terms: D000208:Acute Disease; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D015415:Biomarkers / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood* / Q000187:drug effects; D003327:Coronary Disease / Q000097:blood / Q000188:drug therapy* / Q000401:mortality; D005500:Follow-Up Studies; D006801:Humans; D008824:Michigan / Q000453:epidemiology; D043803:Phenalenes / Q000627:therapeutic use*; D017035:Pravastatin / Q000627:therapeutic use*; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome
chemical_list: D000924:Anticholesteremic Agents; D015415:Biomarkers; D008078:Cholesterol, LDL; D043803:Phenalenes; C030462:atrovenetin; D017035:Pravastatin