[Orbital fat evaluation after enucleation and evisceration in rabbits].
OBJECTIVE
To evaluate rabbit adipocytes of the orbital fat tissue after enucleation and evisceration.


METHODS
Twenty-tree specimens from 23 rabbits aged 42 days which had undergone socket surgery (evisceration and enucleation) were evaluated. The animals were sacrificed on the 30th, 90th and 180th postoperative day. The orbital fat tissue was prepared for light microscope evaluation (magnification: 200x) and analyzed by IpWin 32 software program. The number of cells in each field and the area of each adipocyte were used to calculate the cell median area. The data were compared between the groups (enucleation and evisceration) and submitted to statistical analysis by a non-parametrical test.


RESULTS
There were no statistical differences when considering the mean area of adipocytes between enucleation or evisceration or time of sacrifice.


CONCLUSIONS
The volume decrease in the anophthalmic cavity is not related to orbital fat atrophy. The genesis of orbital volume reduction might result from the spacial distribution and interrelationships of the orbital soft tissue rather than changes in volume of adipocytes.
Shiratori
Claudia Akemi
CA
Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP.
Schellin
Silvana Artioli
SA
Marques
Mariângela E Alencar
ME
Padovani
Carlos Roberto
CR
Padovani
Carlos Roberto Pereira
CR
D017667:Adipocytes; D000273:Adipose Tissue / Q000033:anatomy & histology* / Q000166:cytology; D000818:Animals; D002452:Cell Count; D015353:Eye Enucleation; D009915:Orbit / Q000033:anatomy & histology* / Q000166:cytology / Q000601:surgery; D017233:Orbit Evisceration; D011446:Prospective Studies; D011817:Rabbits; D013997:Time Factors