title: Synergistic antibacterial activity of cefotaxime and the penem HRE 664 in an improved in vitro model simulating serum and tissue pharmacokinetics.
authors.affiliation: Pharma Research, Hoechst AG, Frankfurt/M., FRG.
authors.forename: D
authors.initials: D
authors.lastname: Isert
authors.forename: N
authors.initials: N
authors.lastname: Klesel
authors.forename: A
authors.initials: A
authors.lastname: Markus
authors.forename: G
authors.initials: G
authors.lastname: Seibert
authors.forename: E
authors.initials: E
authors.lastname: Schrinner
mesh_terms: D000900:Anti-Bacterial Agents / Q000097:blood / Q000493:pharmacokinetics / Q000494:pharmacology; D002439:Cefotaxime / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology*; D004357:Drug Synergism; D005285:Fermentation; D007700:Kinetics; D007769:Lactams / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology*; D008954:Models, Biological; D014018:Tissue Distribution
chemical_list: D000900:Anti-Bacterial Agents; D007769:Lactams; C053338:HRE 664; D002439:Cefotaxime