title: A novel index to estimate the corpus callosum morphometry in adults: callosal/supratentorial-supracallosal area ratio.
abstract: OBJECTIVE
  To prospectively investigate the feasibility of a new index (callosal/supratentorial-supracallosal area ratio) in morphometric analysis of the corpus callosum in adults.
  
  
  METHODS
  The callosal and supratentorial-supracallosal areas of 50 healthy volunteers were measured on T1 weighted midsagittal magnetic resonance images. Mean value and variation coefficient for the index was calculated. In a limited subset of subjects (n=25), an interobserver agreement study was conducted to estimate the reproducibility of the index.
  
  
  RESULTS
  There was a statistically significant difference between the area for corpus callosum and supratentorial-supracallosal regions in males and females, although the calculated ratio (index) had no sex-difference. When compared to the literature, the variation coefficient was relatively lower (12.0%), with good interobserver agreement (Pearson correlation analysis, r=0.83).
  
  
  CONCLUSIONS
  Callosal/supratentorial-supracallosal area ratio might serve as a reliable index in morphometric analysis of the corpus callosum in adults.
authors.affiliation: Department of Radiology, Erciyes University School of Medicine, Kayseri, Turkey, Turkey. nerdogan@erciyes.edu.tr
authors.forename: Nuri
authors.initials: N
authors.lastname: Erdoğan
authors.forename: Harun
authors.initials: H
authors.lastname: Ulger
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Tuna
authors.forename: Aylin
authors.initials: A
authors.lastname: Okur
mesh_terms: D000293:Adolescent; D000328:Adult; D003337:Corpus Callosum / Q000033:anatomy & histology* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012016:Reference Values; D015203:Reproducibility of Results