title: [Analgesic effects of electroacupuncture of different pulse waveforms in the rat of adjuvant arthritis].
abstract: OBJECTIVE
  To explore the best pulse waveform of electroacupuncture for treatment of adjuvant arthritis (AA).
  
  
  METHODS
  Forty Wistar rats were randomly divided into 5 groups. The electroacupuncture groups of AA were treated with different pulse waveforms of electroacupuncture, respectively. Pain threshold, swelling degrees of joint, and contents of 5-HT, beta-EP and LEK in local tissues of inflammation were observed.
  
  
  RESULTS
  After the treatment, pain thresholds of the electroacupuncture groups with different pulse waveforms were higher than that of the model group (P < 0.05, P < 0.01); the local swelling degrees of inflammation in the electroacupuncture group were higher than that in the normal group (P < 0. 01), but was lower than that in the model group (P < 0.05, P < 0. 01); the contents of 5-HT in local tissues of inflammation in the electroacupuncture groups were lower than that in the model group (P < 0.05, P < 0.01); in comparison with the model group, the electroacupuncture of sound-electric wave increased the contents of beta-EP and LEK (P < 0.01, P < 0.05) and the electroacupuncture of intermittent wave increased the content of beta-EP in local tissues of inflammation (P < 0.05).
  
  
  CONCLUSIONS
  Sound-electric wave is the best pulse waveform of electroacupuncture for treatment of adjuvant arthritis.
authors.affiliation: College of Acupuncture & Moxibustion, Shanghai University of TCM, Shanghai 201203, China. happykuai2004@msn.com
authors.forename: Le
authors.initials: L
authors.lastname: Kuai
authors.forename: Hua-Yuan
authors.initials: HY
authors.lastname: Yang
authors.forename: Tang-Yi
authors.initials: TY
authors.lastname: Liu
authors.forename: Ming
authors.initials: M
authors.lastname: Gao
mesh_terms: D015667:Acupuncture Analgesia; D000700:Analgesics; D000818:Animals; D001169:Arthritis, Experimental / Q000628:therapy; D015671:Electroacupuncture; D006801:Humans; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000700:Analgesics