Knowledge-driven lead discovery.
Virtual screening encompasses several computational approaches which have proven valuable for identifying novel leads. These approaches rely on available information. Herein, we review recent successful applications of virtual screening. The extension of virtual screening methodologies to target families is also briefly discussed.
Pirard
Bernard
B
Aventis Pharma Deutschland GmbH, A Company of the Sanofi-Aventis Group, Chemical Sciences, Drug Design, Building G878, D-65926 Frankfurt am Main, Germany. bernard.pirard@sanofi-aventis.com
D001185:Artificial Intelligence; D019295:Computational Biology; D003198:Computer Simulation; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D004364:Pharmaceutical Preparations / Q000145:classification; D021281:Quantitative Structure-Activity Relationship
D004364:Pharmaceutical Preparations