Development of a computer-aided diagnosis system for a new modality of renal replacement therapy: an integrated approach combining both peritoneal dialysis and hemodialysis.
The authors developed a computer-aided diagnosis system that includes a simple clinical test for the chronic renal disease patient who needs an integrated approach that combines both peritoneal dialysis and hemodialysis (PD-HD therapy). In this case study, the system simulated and estimated the dialysis outcome, the ultrafiltration volume and nutritional analysis by employing a pharmacokinetic model, and assessed the peritoneal permeable enhancement that can be a grave complication with peritoneal dialysis. This system requires only a minimum amount of nursing time and may be able to predict the optimal treatment schedule for PD-HD therapy and provide therapeutic monitoring in long-term peritoneal dialysis.
Hamada
Hiroyuki
H
Laboratory for Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan. hamada@brs.kyushu-u.ac.jp
Namoto
Shinji
S
Yamada
Ryo
R
Yamashita
Akihiro C
AC
Ishizaki
Makoto
M
Okamoto
Masahiro
M
D003198:Computer Simulation; D015314:Dialysis Solutions / Q000493:pharmacokinetics*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008954:Models, Biological; D010530:Peritoneal Dialysis / Q000379:methods*; D006435:Renal Dialysis / Q000379:methods*; D012984:Software
D015314:Dialysis Solutions