Osteitis in chronic rhinosinusitis.
The presence of inflammation and remodeling within the bone of the paranasal sinuses has been demonstrated in animal and human models of chronic rhinosinusitis. This form of osteitis is present in the underlying bone of affected mucosa and can spread to involve distant sites within the paranasal sinuses. This potential for distant involvement has implications for the medical and surgical management of chronic rhinosinusitis and may contribute to chronic rhinosinusitis refractory to management.
Chiu
Alexander G
AG
Division of Rhinology, Department of Otorhinolaryngology-Head and Neck Surgery, 5 Ravdin Building, 3400 Spruce Street, University of Pennsylvania, Philadelphia, PA 19104, USA. Alexander.chiu@uphs.upenn.edu
D000818:Animals; D016723:Bone Remodeling / Q000502:physiology; D002908:Chronic Disease; D004195:Disease Models, Animal; D006801:Humans; D009297:Nasal Mucosa / Q000503:physiopathology; D010000:Osteitis / Q000209:etiology*; D010254:Paranasal Sinus Diseases / Q000209:etiology*; D020545:Respiratory Mucosa / Q000503:physiopathology; D012220:Rhinitis / Q000150:complications* / Q000628:therapy; D012852:Sinusitis / Q000150:complications* / Q000628:therapy