title: Large-cell calcifying sertoli cell tumour of the testis detected at screening of a family with Carney syndrome.
abstract: We report the detection of a large-cell calcifying Sertoli cell tumour (LCCSCT) in a 34-year-old male during screening of a family with Carney syndrome. The patient had ignored the testicular swelling for 7 years. He also had a cardiac myxoma. The LCCSCT in this patient had prognostically unfavourable features such as large size (>6 cm) and a high mitotic rate. There is only one previous report of a malignant LCCSCT in a patient with Carney syndrome.
authors.affiliation: Department of Pathology, Faculty of Medicine, Colombo, Sri Lanka.
authors.forename: S N
authors.initials: SN
authors.lastname: Jayasena
authors.forename: J T N
authors.initials: JT
authors.lastname: Ariyasinghe
authors.forename: D M R
authors.initials: DM
authors.lastname: Gunawardena
authors.forename: S A S
authors.initials: SA
authors.lastname: Gunawardena
authors.forename: M V C
authors.initials: MV
authors.lastname: de Silva
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000235:genetics; D009919:Orchiectomy; D012307:Risk Factors; D012707:Sertoli Cell Tumor / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery