title: The molecular basis of prostate cancer.
abstract: Cancer involves accumulation of genetic alterations. This review highlights the alterations in control pathways for cell division, development, DNA repair, angiogenesis and cell death that are believed to be key players in the development of prostate cancer.
authors.affiliation: Institute of Cancer Research, Male Urological Cancer Research Centre, Sutton, Surrey SM2 5NG.
authors.forename: A Yvonne
authors.initials: AY
authors.lastname: Olsson
authors.forename: Colin S
authors.initials: CS
authors.lastname: Cooper
mesh_terms: D017209:Apoptosis / Q000502:physiology; D004260:DNA Repair / Q000502:physiology; D053823:Hedgehog Proteins; D006657:Histones / Q000378:metabolism; D006801:Humans; D008297:Male; D008938:Mitosis / Q000502:physiology; D015513:Oncogene Proteins / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D011944:Receptors, Androgen / Q000502:physiology; D016160:Retinoblastoma Protein / Q000378:metabolism; D015534:Trans-Activators / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism; D051153:Wnt Proteins / Q000378:metabolism; D000071676:Zinc Finger Protein GLI1
chemical_list: D053823:Hedgehog Proteins; D006657:Histones; D015513:Oncogene Proteins; D011944:Receptors, Androgen; D016160:Retinoblastoma Protein; D015534:Trans-Activators; D014157:Transcription Factors; D051153:Wnt Proteins; D000071676:Zinc Finger Protein GLI1; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt