Lobular carcinoma of the breast metastatic to the uterus in a patient under adjuvant anastrozole therapy.
This is the first report of breast carcinoma metastatic to the endometrium in a patient on adjuvant anastrozole therapy. We report a case of metastatic lobular carcinoma of the breast in a 63-year-old patient on adjuvant anastrozole therapy for 8 months. She was asymptomatic and metastatic endometrium was diagnosed after transvaginal ultrasound revealed suspicious findings along with elevated Ca 15-3 levels. As further work up showed no other metastatic sites her uterus was taken out along with her ovaries and pelvic lymph nodes. Uterine metastases should be kept in mind in asymptomatic patients on anastrozole therapy.
Erkanli
Serkan
S
Department of Obstetrics & Gynecology, Baskent University School of Medicine, Seyhan- Adana, Turkey. serkanli@tnn.net
Kayaselcuk
Fazilet
F
Kuscu
Esra
E
Bolat
Filiz
F
Sakalli
Hakan
H
Haberal
Ali
A
D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy* / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D018275:Carcinoma, Lobular / Q000188:drug therapy* / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D018396:Mucin-1 / Q000097:blood; D009570:Nitriles / Q000627:therapeutic use*; D010052:Ovariectomy; D014230:Triazoles / Q000627:therapeutic use*; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
D018931:Antineoplastic Agents, Hormonal; D047072:Aromatase Inhibitors; D018396:Mucin-1; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole; D007633:Keratins