title: [Observation of the relationship between systemic hypotension and sudden sensorineural deafness in young subjects].
abstract: OBJECTIVE
  To confirm whether systemic hypotension influences the genesis of sudden sensorineural deafness(SSD) in young people.
  
  
  METHODS
  Twenty-eight untreated young patients diagnosed as SSD in experimental group were compared with 30 age- and sex- matched subjects in control group. Both groups have received the clinic BP testing, 24 hour BP monitoring and their indexes about lipid metabolism were examined and recorded. The statistical analysis was carried out on the data obtained from 2 groups.
  
  
  RESULTS
  The average clinic and 24 hour BP values in patients with SSD were significantly lower. The hypotension (diagnosed according to ISD standard) occurred more frequently in SSD group. There was no difference in metabolism indexes between 2 groups.
  
  
  CONCLUSIONS
  Systemic hypotension which can cause perfusion damage in cochlea can be considered as a possible cause responsible for the development of SSD in young subjects. It's necessary to keep blood pressure monitoring and avoid applying vasodilating drugs until a suspecting or known hypotensive condition is associated with hearing loss.
authors.affiliation: Department of Otorhinolaryngology, the Drum Tower Hospital Affiliated of the Medical School in Nanjing University, Nanjing, 210008, China. lsqsissy@jlonline.com
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.forename: Xia
authors.initials: X
authors.lastname: Gao
authors.forename: Wandong
authors.initials: W
authors.lastname: She
authors.forename: Zhaohe
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000328:Adult; D001795:Blood Pressure Determination; D016022:Case-Control Studies; D003051:Cochlea / Q000473:pathology; D005260:Female; D003639:Hearing Loss, Sudden / Q000503:physiopathology*; D006801:Humans; D007022:Hypotension; D008297:Male; D008875:Middle Aged; D055815:Young Adult