title: Health-related quality of life and health locus of control beliefs among HIV-infected treated patients.
abstract: OBJECTIVE
  This study examined the relations between health locus of control (HLOC) beliefs and health-related quality of life (HRQL) in 302 HIV-infected patients enrolled in a French cohort, 44 months (M44) after they began highly active antiretroviral therapy (HAART).
  
  
  METHODS
  HLOC beliefs were measured with the Multidimensional Health Locus of Control (MHLOC) scale and HRQL, with the Medical Outcome Study Short-Form Health Survey (MOS-SF-36).
  
  
  RESULTS
  Internal HLOC beliefs at the initiation of treatment were associated with both physical HRQL in multivariate analysis, while chance HLOC beliefs on beginning HAART were associated with mental HRQL at M44.
  
  
  CONCLUSIONS
  These findings suggest the importance of considering the psychological characteristics and psychosocial beliefs of patients at the initiation of ARV treatment to optimise the long-term HRQL of HIV-infected patient and to develop adaptive intervention on coping strategies.
authors.affiliation: INSERM U379/ORS, Marseille, France. preau@marseille.inserm.fr
authors.forename: Marie
authors.initials: M
authors.lastname: Préau
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Vincent
authors.forename: Bruno
authors.initials: B
authors.lastname: Spire
authors.forename: Véronique
authors.initials: V
authors.lastname: Reliquet
authors.forename: Isabelle
authors.initials: I
authors.lastname: Fournier
authors.forename: Christian
authors.initials: C
authors.lastname: Michelet
authors.forename: Catherine
authors.initials: C
authors.lastname: Leport
authors.forename: Michel
authors.initials: M
authors.lastname: Morin
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods; D001294:Attitude to Health; D015704:CD4 Antigens / Q000097:blood; D003469:Culture; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy / Q000523:psychology*; D006304:Health Status; D006801:Humans; D007389:Internal-External Control; D008297:Male; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D015704:CD4 Antigens