title: GOAT: An R Tool for Analysing Gene Ontologytrade mark Term Enrichment.
abstract: Understanding the composition of gene lists that result from high-throughput experiments requires elaborate processing of gene annotation lists. In this article we present GOAT (Gene Ontology Analysis Tool), a tool based on the statistical software 'R' for analysing Gene Ontologytrade mark (GO) term enrichment in gene lists. Given a gene list, GOAT calculates the enrichment and statistical significance of every GO term and generates graphical presentations of significantly enriched terms. GOAT works for any organism with a genome-scale GO annotation and allows easy updates of ontologies and annotations.
  
  
  BACKGROUND
  GOAT is freely available from http://dictygenome.org/software/GOAT/ CONTACT: Gad Shaulsky (gadi@bcm.tmc.edu).
authors.affiliation: Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USADepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Qikai
authors.initials: Q
authors.lastname: Xu
authors.forename: Gad
authors.initials: G
authors.lastname: Shaulsky