title: Extensive myofascial necrosis: a delayed complication of botulinum toxin therapy.
abstract: Botulinum toxin is now an important therapeutic agent in various clinical specialties. Although a lot is known about its short-term effects, little is known about the long-term effects or delayed complications. Most of the therapeutic effects appear within a week and last for 10-12 weeks. In most cases, the side effects are mild and often self-limiting and tend to occur within the first week. Myofascial necrosis and delayed onset of side effects are rarely reported and present a new challenge for a drug that has been proclaimed as an anti-ageing drug by the lay press and is widely used outside the licensed indications.
authors.affiliation: Department of Surgery, Gwynedd Hospital, Bangor LL18 5UJ-NW Wales, UK. eagaba@hotmail.com
authors.forename: A E
authors.initials: AE
authors.lastname: Agaba
authors.forename: S
authors.initials: S
authors.lastname: Mahmoud
authors.forename: H
authors.initials: H
authors.lastname: Esmail
authors.forename: J
authors.initials: J
authors.lastname: Sutton
authors.forename: J C
authors.initials: JC
authors.lastname: Bertalot
authors.forename: M M
authors.initials: MM
authors.lastname: Jibani