title: Long-term results of laparoscopic Heller myotomy with partial fundoplication for the treatment of achalasia.
abstract: BACKGROUND
  Treatment options for achalasia include medications, endoscopic balloon dilation, injection of botulinum toxin, or surgery.
  
  
  METHODS
  The clinical course of 75 consecutive patients who underwent minimally invasive Heller myotomy and partial fundoplication for achalasia between 1991 and 2001 was reviewed by means of a questionnaire.
  
  
  RESULTS
  Mean follow-up was 5.3 (range .8 to 10.9) years. Sixty-four percent of questionnaires were returned. Thirty-seven patients (84%) felt much better and 6 (14%) slightly better; 1 (2%) rated the result as unchanged. Twenty-six patients (59%) experienced weight gain. Seven patients (16%) had persistent swallowing problems and 5 (11%) reported frequent reflux. Twenty-five percent underwent additional therapy, including dilation (n = 8, 18%), repeat surgery (n = 2, 5%), and botulinum toxin injection (n = 2, 5%). Eighteen patients (41%) were using a proton pump inhibitor or H2 blocker, three were on a calcium channel blocker (7%), and 1 was using nitroglycerine (2%).
  
  
  CONCLUSIONS
  Laparoscopic Heller myotomy can achieve short- and long-term results comparable to open surgery and should be considered the treatment of choice for patients suffering from achalasia. Despite the frequent need for further therapy, patient satisfaction is good.
authors.affiliation: Department of Surgery, Mayo Clinic Jacksonville, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
authors.forename: Hugo
authors.initials: H
authors.lastname: Bonatti
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Hinder
authors.forename: Josef
authors.initials: J
authors.lastname: Klocker
authors.forename: Beate
authors.initials: B
authors.lastname: Neuhauser
authors.forename: Alexander
authors.initials: A
authors.lastname: Klaus
authors.forename: Sami R
authors.initials: SR
authors.lastname: Achem
authors.forename: Kenneth
authors.initials: K
authors.lastname: de Vault
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004931:Esophageal Achalasia / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000601:surgery*; D017060:Patient Satisfaction; D012189:Retrospective Studies; D013270:Stomach / Q000601:surgery*; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome