Intercellular adhesion molecule-2 (ICAM-2) in experimental trichinosis.
The estimation of the serum adhesion molecules (ICAM-2) levels in experimental trichinosis and evaluation of its impact on the course of infection as well as its possible role in the diagnosis of early trichinosis were studied. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. Investigations of the ICAM-2 role in human trichinosis and applying the findings to improve the diagnostic approaches are highly recommended.
Younis
Azza I H
AI
Department of Parasitology, Faculty of Medicine, Cairo University, Egypt.
Bassiouny
Safiya
S
Abdel Aziz
Jomana
J
Khalafallah
Osama
O
D000818:Animals; D015703:Antigens, CD / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D015815:Cell Adhesion Molecules / Q000097:blood*; D004802:Eosinophilia; D006801:Humans; D051379:Mice; D011897:Random Allocation; D012720:Severity of Illness Index; D017160:Trichinella spiralis; D014235:Trichinellosis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology*
D015703:Antigens, CD; D015415:Biomarkers; D015815:Cell Adhesion Molecules; C065289:ICAM2 protein, human