title: [First diagnostic choice in patients with high clinical suspicion of pulmonary thromboembolism: helical CT or ventilation/perfusion pulmonary scintigraphy?].
abstract: OBJECTIVE
  Comparative analysis about helical CT (ThC) vs ventilation-perfusion pulmonary scintigraphy (V/P Sc) diagnosis effectiveness, as a first diagnosis technique in patients with high clinical suspicion of pulmonary thromboembolism (PT).
  
  
  METHODS
  Prospective study of 30 patients with high clinical suspicion and high Dimer-D levels (> 250 microg/l). The diagnosis was defined as anticoagulant therapeutic prescription and posterior clinical evolution. V/P Sc were performed to each patient within the next 48 h (an average of 14.8 h) after TCh, without anticoagulant treatment. We classified the scintigrams according to the PIOPED criteria and hTC images as positive, negative and indeterminated.
  
  
  RESULTS
  In sixteen patients final diagnosis was PT: in 9 both techniques were positive; in 5 scintigraphy was positive with normal hTC and in 1, hTC was normal with negative scintigraphy. The last case was an indeterminated hTC with negative scintigraphy. In fourteen patients, final diagnosis was non-PT: in 6 both techniques were negative; in 7 scintigraphy was negative with positive hTC and in 1, both results were indeterminated. The sensitivity, specificity, positive predictive value, negative predictive value and efficiency were respectively 87.5, 100, 100, 87.5 and 93 % for V/P Sc and 62, 50, 58.8, 53.8 and 53 % for TCh.
  
  
  CONCLUSIONS
  V/P Sc has better PT diagnosis reliability. It is recommended to do V/P Sc in all patients with high clinical suspicion of PT.
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona.
authors.forename: N
authors.initials: N
authors.lastname: Ferrán
authors.forename: J
authors.initials: J
authors.lastname: Martín-Comín
authors.forename: M
authors.initials: M
authors.lastname: Bajén
authors.forename: D
authors.initials: D
authors.lastname: Carrera
authors.forename: J
authors.initials: J
authors.lastname: Mora
authors.forename: Y
authors.initials: Y
authors.lastname: Ricart
authors.forename: F
authors.initials: F
authors.lastname: Sánchez
authors.forename: R
authors.initials: R
authors.lastname: Mast
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed; D014692:Ventilation-Perfusion Ratio