title: [Not to change therapy unnecessarily! Step 2 opioids at first prescription are of advantage].
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use*; D001416:Back Pain / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009270:Naloxone / Q000008:administration & dosage / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D013993:Tilidine / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid; D009292:Narcotic Antagonists; D009270:Naloxone; D013993:Tilidine