Synthesis of bifunctionalized mesoporous organosilica spheres for high-performance liquid chromatography.
Phenyl-functionalized mesoporous ethane-silicas with spherical morphology were synthesized by one-step co-condensation of phenyltrimethoxysilane (PTMS) and 1,2-bis(trimethoxysily)ethane (BTME) using a triblock copolymer EO(20)PO(70)EO(20) (P123) as template with the aid of a co-surfactant (cetyltrimethylammonium bromide, CTAB) and a co-solvent (ethanol) in acidic medium. Powder X-ray diffraction (XRD), nitrogen sorption measurement and scanning electron microscopy (SEM) show that phenyl-functionalized ethane-silica has wormhole-like mesostructure and perfect spherical morphology. The chemical stability of phenyl-functionalized mesoporous ethane-silica in basic medium is greatly improved owing to the ethane groups bridged in the mesoporous framework. This work also demonstrates that the phenyl-functionalized mesoporous ethane-silica spheres are excellent packing materials for potential application in the reversed-phase high-performance liquid chromatography (HPLC).
Zhu
Guiru
G
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
Yang
Qihua
Q
Jiang
Dongmei
D
Yang
Jie
J
Zhang
Lei
L
Li
Ying
Y
Li
Can
C
D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D011084:Polycyclic Aromatic Hydrocarbons / Q000302:isolation & purification; D012822:Silicon Dioxide / Q000138:chemical synthesis*; D017550:Spectroscopy, Fourier Transform Infrared
D011084:Polycyclic Aromatic Hydrocarbons; D012822:Silicon Dioxide