title: Splenic abscess caused by Klebsiella pneumoniae and non-Klebsiella pneumoniae in Taiwan: emphasizing risk factors for acquisition of Klebsiella pneumoniae splenic abscess.
abstract: Klebsiella pneumoniae was recently reported to be the major pathogen causing pyogenic splenic abscess in Taiwan. To better understand the characteristics of K. pneumoniae splenic abscess, which may be helpful in alerting clinicians to this infection entity when dealing with a suspicious patient, patients hospitalized between January 1981 and December 2002 with the diagnosis of splenic abscess were included in a retrospective study. Among the 38 enrolled patients, 9 (23.7%) suffered from K. pneumoniae splenic abscess. Compared to those with non-K. pneumoniae splenic abscess, patients suffering from splenic abscess caused by K. pneumoniae had a higher prevalence of underlying diabetes mellitus (88.9% vs 37.9%; p = 0.006) and higher incidence of concomitant liver abscess (44.4% vs 0%; p < 0.001) caused by the same pathogen. When dealing with patients suffering from K. pneumoniae splenic abscess, clinicians should work up to exclude a concomitant liver abscess caused by the same pathogen.
authors.affiliation: Division of Infectious Diseases, Chang-Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, Republic of China.
authors.forename: Chen-Hsiang
authors.initials: CH
authors.lastname: Lee
authors.forename: Tsung-Hui
authors.initials: TH
authors.lastname: Hu
authors.forename: Jien-Wei
authors.initials: JW
authors.lastname: Liu
mesh_terms: D000038:Abscess / Q000209:etiology* / Q000382:microbiology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000209:etiology* / Q000382:microbiology; D007711:Klebsiella pneumoniae; D008100:Liver Abscess / Q000150:complications; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013158:Splenic Diseases / Q000209:etiology* / Q000382:microbiology; D013624:Taiwan