title: [Risk factors for metastasis and recurrence of hepatocellular carcinoma at different stages].
abstract: OBJECTIVE
  To analyze the risk factors for metastasis and recurrence of hepatocellular carcinoma (HCC) postoperatively.
  
  
  METHODS
  Data of 270 cases of postoperative HCC were analyzed by SPSS software retrospectively.
  
  
  RESULTS
  Out of the 270 cases, 162 got follow-up study and 136 showed metastasis and recurrence. Lots of risk factors induced the recurrence of HCC, such as AFP, tumor form, venous blood invasion, HBV infection, resection dimension and perioperative transfusion. There were different risk factors at different stages.
  
  
  CONCLUSIONS
  The early recurrence of HCC may be mediated by macro- or micro-vessel blood invasion and metastasis, the late recurrence by multicentric carcinogenesis or introhepatic cacinoma de novo.
authors.affiliation: Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. Lianyueyang@hotmail.com
authors.forename: Di-Peng
authors.initials: DP
authors.lastname: Ou
authors.forename: Lian-Yue
authors.initials: LY
authors.lastname: Yang
authors.forename: Geng-Wen
authors.initials: GW
authors.lastname: Huang
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Tao
authors.forename: Xiang
authors.initials: X
authors.lastname: Ding
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Chang
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D002681:China / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D011184:Postoperative Period; D012189:Retrospective Studies; D012307:Risk Factors