What is a 'failure' of bisphosphonate therapy for osteoporosis?
Assessing the effectiveness of bisphosphonate therapy is problematic. Bone mineral density and markers of bone turnover are often used, but the true measure is prevention of new fractures.
Carey
John J
JJ
Department of Rheumatic and Immunologic Diseases, The Cleveland Clinic Foundation, OH 44195, USA. careyj@ccf.org
D000284:Administration, Oral; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004164:Diphosphonates / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy* / Q000378:metabolism; D010349:Patient Compliance; D017211:Treatment Failure
D050071:Bone Density Conservation Agents; D004164:Diphosphonates