title: Pseudomembranous tracheobronchitis caused by Aspergillus in immunocompromised patients.
abstract: We report 2 cases of Aspergillus pseudomembranous tracheobronchitis in patients with diabetes. The first patient succumbed to progressive obstructive respiratory failure despite mechanical ventilation and antifungal therapy. However, the second patient survived. Aspergillus tracheobronchitis should be considered in immuno-compromised patients presenting with cough, chest pain, fever, dyspnea and upper airway obstruction. Early bronchoscopy and histologic examination should be performed. Early, appropriate treatment may be life saving.
authors.affiliation: Chest Division, Department of Medicine, Mackay Memorial Hospital, No. 92, Section 2, Chung-San N Road, Taipei, Taiwan.
authors.forename: Shang-Miao
authors.initials: SM
authors.lastname: Chang
authors.forename: Hsu-Tah
authors.initials: HT
authors.lastname: Kuo
authors.forename: Fung-J
authors.initials: FJ
authors.lastname: Lin
authors.forename: Chi-Yuan
authors.initials: CY
authors.lastname: Tzen
authors.forename: Chin-Yin
authors.initials: CY
authors.lastname: Sheu
mesh_terms: D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001230:Aspergillus / Q000302:isolation & purification / Q000472:pathogenicity; D001991:Bronchitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D048909:Diabetes Complications / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D014136:Tracheitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology