title: [Analysis of prognostic factors of malignant ovarian tumor after fertility-preserving treatment].
abstract: OBJECTIVE
  To explore the prognostic factors of malignant ovarian tumor after fertility-preserving treatment.
  
  
  METHODS
  189 patients with malignant ovarian tumor who had undergone fertility-preserving management in the past 20 years were retrospectively analyzed. The correlative factors for survival, recurrence and reproductive status were evaluated. Among the patients, 136 cases suffered from ovarian germ cell tumor (OGCT), 31 cases suffered from ovarian sex cord-stromal tumor (OSCST), and 22 cases suffered from epithelial ovarian cancer (EOC). The median follow-up time of different groups was 50 months for OGCT, 46 months for OSCST, 45 months for EOC respectively.
  
  
  RESULTS
  The 5-year survival rates for OGCT, OSCST and EOC groups were 94.0% (131/134), 77.1% (26/30) and 64.7% (16/21) respectively. The recurrent rates were 29.9% (40/134), 20.0% (6/30) and 47.6% (10/21) respectively. 46 babies were delivered during the follow-up period. Standard chemotherapy was the most important prognostic factor for OGCT. FIGO stage and standard chemotherapy were favourable factors for prognosis in OSCST group. The important prognostic factors included FIGO stage and standard comprehensive surgical staging for EOC.
  
  
  CONCLUSIONS
  Fertility-preserving treatment should be considered for OGCT without limitation of FIGO stage, whereas it should be performed individually for OSCST and EOC. The treatment outcome for OGCT is the best, for EOC the worst.
authors.affiliation: Department of Obestetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Bejing 100730, China.
authors.forename: Ding-yuan
authors.initials: DY
authors.lastname: Zeng
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Hui-fang
authors.initials: HF
authors.lastname: Huang
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Ling-ya
authors.initials: LY
authors.lastname: Pan
authors.forename: Jia-xin
authors.initials: JX
authors.lastname: Yang
authors.forename: Jing-he
authors.initials: JH
authors.lastname: Lang
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control*; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000517:prevention & control; D009373:Neoplasms, Germ Cell and Embryonal / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods*; D011247:Pregnancy; D011379:Prognosis; D018570:Risk Assessment; D018312:Sex Cord-Gonadal Stromal Tumors / Q000601:surgery; D016019:Survival Analysis