title: [Post-traumatic stress disorder and substance use disorder: treatment intervention].
abstract: There is an increasing interest to find efficacious treatments for patients with post-traumatic stress disorder (PTSD) and comorbid substance use disorder (SUD). Therefore, in this paper the studies published on the psychological and pharmacological treatment for the management of comorbid PTSD and SUD will be discussed, as these are highly prevalent and shown in part I. The few studies published to date suggest that patients benefit most form an integrated treatment approach for the comorbid disorders. Psychological treatments based on cognitive behavioural strategies appear to be useful for patients with PTSD and comorbid SUD disorder. Medications such as SSRIs and particularly sertraline that efficacious for PTSD, seem to be as well for this dual disorder. In addition, pharmacological options, among them quetiapine or bupropion have shown promising results in preliminary studies.
authors.affiliation: Psiquiatra, Instituto de Drogas y Conductas Adictivas, Universidad Cardenal Herrera, CEU y Agencia Valenciana de Salud, España. martinez_josrag@gva.es
authors.forename: José
authors.initials: J
authors.lastname: Martínez Raga
authors.forename: Javier
authors.initials: J
authors.lastname: Didia-Attas
authors.forename: Alfredo
authors.initials: A
authors.lastname: Job
authors.forename: Carlos
authors.initials: C
authors.lastname: Knecht C
authors.forename: Sonsoles
authors.initials: S
authors.lastname: Cepeda
authors.forename: Luis
authors.initials: L
authors.lastname: San
authors.forename: Bartolome
authors.initials: B
authors.lastname: Pérez-Gálvez
mesh_terms: D006801:Humans; D013313:Stress Disorders, Post-Traumatic / Q000628:therapy*; D019966:Substance-Related Disorders / Q000628:therapy*