Pseudomembranous tracheobronchitis caused by Aspergillus in immunocompromised patients.
We report 2 cases of Aspergillus pseudomembranous tracheobronchitis in patients with diabetes. The first patient succumbed to progressive obstructive respiratory failure despite mechanical ventilation and antifungal therapy. However, the second patient survived. Aspergillus tracheobronchitis should be considered in immuno-compromised patients presenting with cough, chest pain, fever, dyspnea and upper airway obstruction. Early bronchoscopy and histologic examination should be performed. Early, appropriate treatment may be life saving.
Chang
Shang-Miao
SM
Chest Division, Department of Medicine, Mackay Memorial Hospital, No. 92, Section 2, Chung-San N Road, Taipei, Taiwan.
Kuo
Hsu-Tah
HT
Lin
Fung-J
FJ
Tzen
Chi-Yuan
CY
Sheu
Chin-Yin
CY
D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001230:Aspergillus / Q000302:isolation & purification / Q000472:pathogenicity; D001991:Bronchitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D048909:Diabetes Complications / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D014136:Tracheitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology