title: Phytochemical profiling of New and Old World Hypericum (St. John's Wort) species.
abstract: Botanical extracts of Hypericum perforatum L. (common St. John's Wort) are used in the USA and in Europe as a treatment for mild to moderate depression, although controversy surrounds the identity of the active constituent(s). RP-HPLC with photodiode array detection was used to separate and quantify nine compounds of pharmacological interest in extracts from 74 taxa of Hypericum native to the Old and New World. Chemical profiles of these constituents may be used to distinguish extracts of H. perforatum from those of other species of Hypericum, and to indicate species that may be of interest for further phytochemical investigation.
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, University of Mississippi, University 38677, USA.
authors.forename: Sara L
authors.initials: SL
authors.lastname: Crockett
authors.forename: Brian
authors.initials: B
authors.lastname: Schaneberg
authors.forename: Ikhlas A
authors.initials: IA
authors.lastname: Khan
mesh_terms: D005843:Geography; D020902:Hypericum / Q000737:chemistry* / Q000145:classification*; D010936:Plant Extracts / Q000737:chemistry*; D013045:Species Specificity
chemical_list: D010936:Plant Extracts