title: DNA ligases are specifically inhibited by anthracyclines with a free 3'-amino group.
authors.affiliation: Istituto di Genetica Biochimica ed Evoluzionistica, C.N.R., Università di Pavia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Montecucco
authors.forename: G
authors.initials: G
authors.lastname: Pedrali-Noy
authors.forename: S
authors.initials: S
authors.lastname: Spadari
authors.forename: E
authors.initials: E
authors.lastname: Zanolin
authors.forename: M T
authors.initials: MT
authors.lastname: Chiesa
authors.forename: G
authors.initials: G
authors.lastname: Ciarrocchi
mesh_terms: D000588:Amines; D018943:Anthracyclines / Q000737:chemistry / Q000494:pharmacology*; D017122:Bacteriophage T4 / Q000187:drug effects / Q000201:enzymology; D002470:Cell Survival / Q000187:drug effects; D011088:DNA Ligases / Q000037:antagonists & inhibitors*; D004278:DNA, Superhelical / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D059004:Topoisomerase I Inhibitors
chemical_list: D000588:Amines; D018943:Anthracyclines; D004278:DNA, Superhelical; D004791:Enzyme Inhibitors; D059004:Topoisomerase I Inhibitors; D011088:DNA Ligases