[Changes of edema associated with I-125 prostate brachytherapy].
We have been performing TRUS-guided transperineal prostate brachytherapy with I-125 for prostate-confined adenocarcinoma since October 2003. We examined prostate volume using CT scanning on Day 1, Day 15, and Day 30 in the initial 15 patients, and investigated time-dependent changes of edema associated with I-125 prostate brachytherapy. Prostate volume had increased to 173% of the average on the first day after implantation. Improvements in the swelling of the prostate showed decreases in 30% in the first 2 weeks (Days 1-15) and 12% in the second 2 weeks (Days 15-30). V100 and D 90% showed statistically significant increases of 5.5% and 8.4% in the first 2 weeks after implantation and 2.3% and 5.2% in the second 2 weeks (Days 15-30). We considered one month a suitable time at which to calculate post-planning because V100 and D 90% changed little statistically.
Aoki
Manabu
M
Division of Radiation oncology, Department of Radiology, Jikei University School of Medicine.
Miki
Kenta
K
Takahashi
Hiroyuki
H
Takagi
Sayako
S
Fukuda
Ichirou
I
Honda
Chikara
C
Kobayashi
Masao
M
Egawa
Shin
S
Kanehira
Chihiro
C
D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D004487:Edema / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011469:Prostatic Diseases / Q000209:etiology / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted
D007457:Iodine Radioisotopes