title: Anaplasma phagocytophilum-infected ticks, Japan.
abstract: We report Anaplasma phagocytophilum infection of Ixodes persulcatus and I. ovatus ticks in Japan. Unique p44/msp2 paralogs (and/or 16S rRNA genes) were detected in tick tissues, salivary glands, and spleens of experimentally infected mice. These findings indicate the public health threat of anaplasmosis in Japan.
authors.affiliation: Laboratory of Experimental Microbiology, Institute for Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga, Shizuoka 422-8526, Japan. ohashi@u-shizuoka-ken.ac.jp
authors.forename: Norio
authors.initials: N
authors.lastname: Ohashi
authors.forename: Megumi
authors.initials: M
authors.lastname: Inayoshi
authors.forename: Kayoko
authors.initials: K
authors.lastname: Kitamura
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Kawamori
authors.forename: Daizoh
authors.initials: D
authors.lastname: Kawaguchi
authors.forename: Yuusaku
authors.initials: Y
authors.lastname: Nishimura
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Naitou
authors.forename: Midori
authors.initials: M
authors.lastname: Hiroi
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Masuzawa
mesh_terms: D041081:Anaplasma phagocytophilum / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D003520:Cyclophosphamide / Q000494:pharmacology; D004269:DNA, Bacterial / Q000032:analysis / Q000302:isolation & purification; D016873:Ehrlichiosis / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D016867:Immunocompromised Host; D018884:Ixodes / Q000145:classification / Q000382:microbiology*; D007564:Japan; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D010802:Phylogeny; D012469:Salivary Glands / Q000382:microbiology; D017422:Sequence Analysis, DNA
chemical_list: D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial; C488283:msp2 protein, Anaplasma phagocytophilum; C450839:p44 protein, Anaplasma phagocytophila; D003520:Cyclophosphamide