title: [Effect of aggregation extent of microperoxidase-8 on its interaction with La3+].
abstract: Oxygen of two propionic acid groups of the heme group in an MP-8 molecule, leading to an increase in the non-planarity of the porphyrin ring of the heme group. The increasing extent in the non-planarity of the porphyrin ring of the heme group due to the interaction of La3+ and MP-8 molecule would be significantly decreased because NaCl could increase the aggregation extent of MP-8 molecules. Although methanol can reduce the aggregation extent of MP-8 molecules, it has little influence on the increasing extent in the non-planarity of the porphyrin ring of the heme group due to the interaction of La3+ and MP-8 molecule.
authors.affiliation: College of Chemistry and Environment Science, Nanjing Normal University, Nanjing 210097, China.
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Chen
authors.forename: Xiao-hua
authors.initials: XH
authors.lastname: Huang
authors.forename: Jiang-yan
authors.initials: JY
authors.lastname: Du
authors.forename: Yu-ying
authors.initials: YY
authors.lastname: Feng
authors.forename: Chang-peng
authors.initials: CP
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Xing
authors.forename: Tian-hong
authors.initials: TH
authors.lastname: Lu
mesh_terms: D006418:Heme / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry* / Q000378:metabolism; D000432:Methanol / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D010544:Peroxidases / Q000737:chemistry* / Q000378:metabolism; D011166:Porphyrins / Q000737:chemistry; D011422:Propionates / Q000737:chemistry; D011485:Protein Binding / Q000187:drug effects; D011487:Protein Conformation / Q000187:drug effects; D012965:Sodium Chloride / Q000737:chemistry / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet
chemical_list: D011166:Porphyrins; D011422:Propionates; C028521:lanthanum chloride; D006418:Heme; D012965:Sodium Chloride; D007811:Lanthanum; D010544:Peroxidases; C021799:microperoxidase; C029658:propionic acid; D010100:Oxygen; D000432:Methanol