Imaging tumour angiogenesis.
The development of neovasculature via angiogenesis is a vital component of many normal physiological processes and a number of disease states. Neovascularisation is critical for the growth of malignant tumours and for the development and survival of metastases. Recently, the potential of non-invasive imaging for the functional characterisation of neovasculature has become realised. In this review we describe the process of tumour angiogenesis for radiologists and present a summary of the most available computed tomography/magnetic resonance imaging techniques that can depict the functional vascular status of human tumours.
Jeswani
Tony
T
Department of Radiology, Royal Free Hospital, London, NW3 2QG, UK.
Padhani
Anwar R
AR
D003952:Diagnostic Imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D009369:Neoplasms / Q000098:blood supply* / Q000175:diagnosis / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed