title: Hip arthroplasty for ochronosis.
abstract: Alkaptonuria is a metabolic disorder in which homogentisic acid oxidase is absent. Therefore, homogentisic acid accumulates in cartilage and connective tissues. We can diagnose ochronotic arthropathy, a manifestation of long standing alkaptonuria, through careful radiological, physical, and laboratory examination. In this report, we describe 4 cases of ochronotic arthropathy to which we applied cementless total hip prosthesis due to severe hip involvement.
authors.affiliation: Department of Orthopedic Surgery, Karadeniz Technical University Faculty of Medicine, Trabzon 61080, Turkey. serkerim70@yahoo.com
authors.forename: Servet
authors.initials: S
authors.lastname: Kerimoglu
authors.forename: Cetin
authors.initials: C
authors.lastname: Onder
authors.forename: Osman
authors.initials: O
authors.lastname: Aynaci
authors.forename: Cagatay H
authors.initials: CH
authors.lastname: Malkoc
mesh_terms: D000368:Aged; D018771:Arthralgia / Q000175:diagnosis / Q000209:etiology; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D001843:Bone Cements; D005260:Female; D006713:Homogentisic Acid / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D009794:Ochronosis / Q000175:diagnosis* / Q000601:surgery*; D010147:Pain Measurement; D011474:Prosthesis Design; D016059:Range of Motion, Articular / Q000502:physiology; D020127:Recovery of Function; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D006713:Homogentisic Acid