title: A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms.
authors.affiliation: European Molecular Biology Laboratory, Gene Expression Programme, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Wichmann
authors.forename: Jochen
authors.initials: J
authors.lastname: Wittbrodt
authors.forename: Carsten
authors.initials: C
authors.lastname: Schultz
mesh_terms: D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology; D002478:Cells, Cultured; D004285:Dogs; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004847:Epithelial Cells / Q000201:enzymology*; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods*; D006367:HeLa Cells; D006801:Humans; D006868:Hydrolysis; D007668:Kidney / Q000201:enzymology; D008968:Molecular Conformation; D008970:Molecular Weight; D009281:Naphthalenes / Q000494:pharmacology; D063065:Organophosphonates / Q000494:pharmacology; D009990:Oryzias / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D010714:Phosphatidylethanolamines / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D010741:Phospholipases A / Q000037:antagonists & inhibitors / Q000737:chemistry*; D054467:Phospholipases A2; D011753:Pyrones / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014018:Tissue Distribution
chemical_list: D001095:Arachidonic Acids; D004791:Enzyme Inhibitors; D009281:Naphthalenes; D063065:Organophosphonates; D010714:Phosphatidylethanolamines; D011753:Pyrones; C104810:methyl arachidonylfluorophosphonate; C483858:phosphatidylethanolamine; C068314:6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one; D010741:Phospholipases A; D054467:Phospholipases A2