[Study of the usefulness of pharmacist consultations for patients on antiretroviral regimens].
OBJECTIVE
Highly active anti-retroviral therapies (HAART) in HIV treatment can result in complex treatment regimens. We surveyed HIV patients followed in the infectious disease department of Saint-Germain-en-Laye Hospital to assess the interest of offering patients a consultation with a pharmacist.


METHODS
The 3-part questionnaire enabled us to assess the medical and pharmaceutical information given to the patient, adherence, and risk factors for poor observance. The questionnaire was distributed to all patients, regardless of whether they were receiving treatment. A simple adherence score was computed as well as a score for the risk of poor adherence.


RESULTS
Ninety patients returned analyzable questionnaires: 65 (72.2%) thought a pharmaceutical consultation would be useful. They felt it should cover in priority the following subjects: drug interactions (51%), secondary effects (49%), and what to do after forgetting a dose (44%). Treatment was perceived as positive by 82 patients (91%) and tolerated well by 57 (65%). Sixty patients (66.3%) reported that they occasionally forgot a dose, 37 (41.3%) that they regularly did. The results showed good adherence by 61.3% and poor adherence by 38.5%. Risk of non-adherence was significantly associated with three factors: the number of pills to take, the number of daily doses, and the length of the treatment.


CONCLUSIONS
Our survey shows the interest of consultations with pharmacists as a clinical service. By reinforcing the patient's understanding, these can complete and supplement the physician's explanation and instructions on pharmaceutical topics, especially those that could not be addressed during the clinical visit. The main aim of this process is to improve adherence, which is a key element in treatment efficacy.
Guerrault
M-N
MN
Service de pharmacie, CHI de Poissy- Saint-Germain- en-Laye. mnguerrault@chi-poissy-st-germain.fr
Leclerc
C
C
Langevin
S
S
Merian-Brosse
L
L
Brossard
D
D
Welker
Y
Y
D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D004346:Drug Information Services; D005260:Female; D005602:France; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010595:Pharmacists; D011369:Professional-Patient Relations; D011446:Prospective Studies; D012017:Referral and Consultation; D011795:Surveys and Questionnaires