title: NtPDR3, an iron-deficiency inducible ABC transporter in Nicotiana tabacum.
abstract: In plants, the ABC transporter PDR (pleiotropic drug resistance) subfamily is composed of approximately 15 genes, few of which have been analyzed. We have identified NtPDR3, a Nicotiana tabacum PDR gene belonging to a cluster for which no functional data was previously available. NtPDR3 was found to be induced in suspension cells treated with methyl jasmonate, salicylic acid, 1-naphthalene acetic acid, or cembrene, a macrocyclic diterpene. In agreement with the identification of a putative iron deficiency element in the NtPDR3 transcription promoter region, we found that iron deficiency in the culture medium induced NtPDR3 expression, thus suggesting a new function of the PDR transporter family.
authors.affiliation: Unité de Biochimie Physiologique, Institut des Sciences de la Vie, Université Catholique de Louvain, Croix du Sud, 5, B-1348 Louvain-la-Neuve, Belgium.
authors.forename: Eric
authors.initials: E
authors.lastname: Ducos
authors.forename: Staffan
authors.initials: S
authors.lastname: Fraysse
authors.forename: Marc
authors.initials: M
authors.lastname: Boutry
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D000085:Acetates / Q000494:pharmacology; D001483:Base Sequence; D001692:Biological Transport; D002478:Cells, Cultured; D002614:Chelating Agents / Q000494:pharmacology; D003001:Cloning, Molecular; D016384:Consensus Sequence; D003470:Culture Media / Q000032:analysis; D003517:Cyclopentanes / Q000494:pharmacology; D018076:DNA, Complementary; D004224:Diterpenes / Q000494:pharmacology; D004533:Egtazic Acid / Q000494:pharmacology; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D017343:Genes, Plant; D005822:Genetic Vectors; D000090463:Iron Deficiencies; D008969:Molecular Sequence Data; D009280:Naphthaleneacetic Acids / Q000494:pharmacology; D054883:Oxylipins; D010802:Phylogeny; D010937:Plant Growth Regulators / Q000494:pharmacology; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D011401:Promoter Regions, Genetic; D020156:Salicylic Acid / Q000494:pharmacology; D014026:Nicotiana / Q000166:cytology / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D018528:ATP-Binding Cassette Transporters; D000085:Acetates; D002614:Chelating Agents; D003470:Culture Media; D003517:Cyclopentanes; D018076:DNA, Complementary; D004224:Diterpenes; D009280:Naphthaleneacetic Acids; D054883:Oxylipins; D010937:Plant Growth Regulators; D010940:Plant Proteins; C108204:cembrene A; C034182:1-naphthaleneacetic acid; D004533:Egtazic Acid; C072239:methyl jasmonate; D020156:Salicylic Acid