[Surgical therapy for azoospermia with ejaculatory duct obstruction].
OBJECTIVE
To investigate the effect of transurethral resection of ejaculatory ducts (TURED) for azoospermia with ejaculatory duct obstruction (EDO).


METHODS
From June 2003 to December 2004, 20 azoospermia with EDO were diagnosed, diagnostic criteria included a history, physical examination, semen analyses, semen fructose measurement, endocrine assessment, testicular biopsy and transrectal ultrasonography (TRUS); All 20 cases were treated by TURED. Fifteen of them were followed up more than 3 months after the treatment. The semen samples of them were analysed at 3-month intervals in post-therapy.


RESULTS
Semen analyses in all 20 cases showed the typical characteristics of EDO, low semen volume (0.4-1.6 ml), azoospermia, low pH, absent or low semen fructose. TRUS showed the main etiology factor of EDO was a midline cyst in 11, lateral cystic lesions in 2, the remaining 7 cases had dilated ejaculatory duct with or without dilated seminal vesicles. Among 15 cases followed up more than 3 months after TURED, 10/15 (67%) had an improvement in semen parameters and 3/15 (20%) had pregnancies. Semen analyses had not been done in anther 5 cases.


CONCLUSIONS
Transurethral resection of ejaculatory ducts may be a safe and effective method for the treatment of azoospermia with EDO.
Deng
Chun-hua
CH
Department of Urology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
Qiu
Shao-peng
SP
Sun
Xiang-zhou
XZ
Guo
Hai-bin
HB
Wu
Rong-pei
RP
D000328:Adult; D053713:Azoospermia / Q000175:diagnosis / Q000601:surgery*; D004543:Ejaculatory Ducts / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D004598:Electrosurgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000175:diagnosis; D014463:Ultrasonography