title: Autogenous platelet-rich plasma in combination with bovine-derived hydroxyapatite xenograft for treatment of a cystic lesion of the jaw.
abstract: In the last 5 years, many studies about autogenous platelet-rich plasma have been undertaken pointing out its regenerative and reparative properties on tissues. The features of this product are an attribute of platelet cells, which, after cellular interactions, release growth factors. These molecules promote tissue healing and also induce cellular regeneration. Bone is a dynamic tissue subject to balanced processes of bony formation and reabsorption; autologous platelet gel or concentrate (PRP) can be used alone or in association with bony graft for the treatment of bony defect, cystic lesions, alveolar bone defects, and periodontal pockets. Its application fields are oral and maxillofacial surgery, plastic surgery, and general surgery, and it can be applied particularly in patients with coagulation diseases. In our experience, a giant cystic lesion of the jaw was treated with PRP and granules of bovine-derived hydroxyapatite xenograft to enhance bony regeneration and promote tissue healing.
authors.affiliation: Maxillo-Facial Surgery Department, II Faculty of La Sapienza University, S. Andrea Hospital, Rome, Italy.
authors.forename: Evaristo
authors.initials: E
authors.lastname: Belli
authors.forename: Benedetto
authors.initials: B
authors.lastname: Longo
authors.forename: Filippo Marini
authors.initials: FM
authors.lastname: Balestra
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001792:Blood Platelets / Q000502:physiology; D001804:Blood Transfusion, Autologous; D001861:Bone Regeneration / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use*; D002417:Cattle; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007570:Jaw Cysts / Q000601:surgery*; D008336:Mandibular Diseases / Q000601:surgery*; D008875:Middle Aged; D010012:Osteogenesis / Q000502:physiology; D010949:Plasma; D017713:Platelet Transfusion; D014183:Transplantation, Heterologous; D014945:Wound Healing / Q000502:physiology
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D017886:Durapatite