title: Taxonomy and chemical characterization of antibiotics of Streptosporangium Sg 10 isolated from a Saharan soil.
abstract: A new actinomycete strain designated Sg 10, producing antimicrobial substances was isolated from an Algerian soil. Morphological and chemical studies indicated that strain Sg 10 belonged to the genus Streptosporangium. The comparison of its physiological characteristics with those of known species of Streptosporangium showed significant differences with the nearest species Streptosporangium carneum. Analysis of the 16S rDNA sequence of strain Sg 10 showed a similarity level ranging between 96.3% and 97.8% within Streptosporangium species, with S. carneum the most closely related. However, the phylogenetic analysis indicated that strain Sg 10 represent a distinct phyletic line suggesting a new genomic species. The antimicrobial activity of strain Sg 10 showed an antibacterial activity against Gram-positive bacteria as well as an antifungal one. Four active products were isolated from the culture broth using various separation procedures. On the basis of UV-VIS spectrometry, infrared spectroscopy and chemical revelations, the antibiotics were classified in the group of glycosylated aromatics.
authors.affiliation: Laboratoire de Recherche sur les Produits bioactifs et la Valorisation de la Biomasse, Ecole Normale Supérieure de Kouba, BP 92, 16 050 Vieux-Kouba, Alger, Algérie.
authors.forename: Hadjira
authors.initials: H
authors.lastname: Boudjella
authors.forename: Karima
authors.initials: K
authors.lastname: Bouti
authors.forename: Abdelghani
authors.initials: A
authors.lastname: Zitouni
authors.forename: Florence
authors.initials: F
authors.lastname: Mathieu
authors.forename: Ahmed
authors.initials: A
authors.lastname: Lebrihi
authors.forename: Nasserdine
authors.initials: N
authors.lastname: Sabaou
mesh_terms: D000192:Actinomycetales / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D000352:Africa, Northern; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D000898:Antibiosis; D003889:Desert Climate; D010802:Phylogeny; D012988:Soil Microbiology
chemical_list: D000900:Anti-Bacterial Agents