title: Oxidative stress response: a proteomic view.
abstract: The oxidative stress response is characterized by various effects on a range of biologic molecules. When examined at the protein level, both expression levels and protein modifications are altered by oxidative stress. While these effects have been studied in the past by classic biochemical methods, the recent onset of proteomics methods has allowed the oxidative stress response to be studied on a much wider scale. The input of proteomics in the study of oxidative stress response and in the evidence of an oxidative stress component in biologic phenomena is reviewed in this paper.
authors.affiliation: DRDC/ICH, INSERM U 548, CEA-Laboratoire d'Immunochimie, CEA-Grenoble, 17 rue des martyrs, F-38054 Grenoble Cedex 9, France. thierry.rabilloud@cea.fr
authors.forename: Thierry
authors.initials: T
authors.lastname: Rabilloud
authors.forename: Mireille
authors.initials: M
authors.lastname: Chevallet
authors.forename: Sylvie
authors.initials: S
authors.lastname: Luche
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Leize-Wagner
mesh_terms: D000818:Animals; D001695:Biology; D005786:Gene Expression Regulation; D006801:Humans; D018384:Oxidative Stress; D020543:Proteome / Q000235:genetics / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*
chemical_list: D020543:Proteome