title: Acromegaly secondary to growth hormone releasing hormone secretion.
abstract: BACKGROUND
  Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare.
  
  
  OBJECTIVE
  To report a case of acromegaly diagnosed in 1984 and assumed to be pituitary in origin. Sixteen years later, the cause was found to be a GHRH secreting neuroendocrine pancreatic tumour.
  
  
  METHODS
  A case report.
  
  
  CONCLUSIONS
  Although ectopic GHRH production is very rare, endocrinologists should be aware of this possibility in acromegaly patients if a pituitary tumour was not detected using pituitary imaging.
authors.affiliation: Department of Endocrinology, James Connolly Memorial Hospital, Dublin, Ireland. amaragha@yahoo.com
authors.lastname: Agha
authors.forename: L
authors.initials: L
authors.lastname: Farrell
authors.forename: P
authors.initials: P
authors.lastname: Downey
authors.forename: P
authors.initials: P
authors.lastname: Keeling
authors.forename: E
authors.initials: E
authors.lastname: Leen
authors.forename: S
authors.initials: S
authors.lastname: Sreenan
mesh_terms: D000172:Acromegaly / Q000175:diagnosis / Q000503:physiopathology*; D000328:Adult; D005260:Female; D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging; D018358:Neuroendocrine Tumors / Q000503:physiopathology*; D010190:Pancreatic Neoplasms / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed
chemical_list: D013007:Growth Hormone-Releasing Hormone