title: [Effect of electroacupuncture on expression of IFN-gamma-like immunoreactive substance in spinal cord of the rat ].
abstract: OBJECTIVE
  To observe effect of electroacupuncture at "Zusanli" (ST 36) on expression of interferon-gamma (IFN-gamma)-like immunoreactive substance in spinal cord of the rat and to probe the mechanism.
  
  
  METHODS
  The IFN-gamma-like immunoreactive positive cell number in spinal cord of the rat was investigated with immunohistochemical SP method and microscopy.
  
  
  RESULTS
  After electroacupuncture at "Zusanli" (ST 36), IFN-gamma-like immunoreactive positive cell number in the spinal cord of the rat with electroacupuncture plus immunosuppression did not significantly change (P > 0.05). The number of positive cells in the dorsal horn in the rats with immunosuppression was significantly less than that in the normal control group (P < 0.05) with no significant change in other parts and with no significant difference between the electroacupuncture group and the control group (P > 0.05).
  
  
  CONCLUSIONS
  Electroacupuncture at "Zusanli" (ST 36) can increase expression of IFN-gamma-like immunoreactive substance in spinal cord of the rat, and acupuncture activates the nerve-immunoregulative network possibly by IFN-gamma as medium.
authors.affiliation: Department of Animal Science and Technology, Beijing Agricultural College, Beijing 102206, China.
authors.forename: Ge
authors.initials: G
authors.lastname: Hu
authors.forename: Zuo-Jun
authors.initials: ZJ
authors.lastname: Yang
authors.forename: Hui-Qin
authors.initials: HQ
authors.lastname: Duan
authors.forename: Li-Yun
authors.initials: LY
authors.lastname: Gao
authors.forename: Xiang
authors.initials: X
authors.lastname: Mu
authors.forename: Yu-Liang
authors.initials: YL
authors.lastname: Li
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D015671:Electroacupuncture; D007371:Interferon-gamma; D051381:Rats; D013116:Spinal Cord
chemical_list: D007371:Interferon-gamma