title: [Comparative histologic study of implants (magnets) in orbits of female rabbits].
abstract: OBJECTIVE
  To evaluate microscopically the signs of inflammatory reaction due to the fixation of an orbitary implant (magnet, covered by gold).
  
  
  METHODS
  An experimental study was performed in 54 adult female rabbits, divided into 3 groups of eighteen with 3 subgroups of 6; an evaluation at 1, 3 and 6 postoperative weeks was performed. An implant (magnet, covered by gold) was fixed in the inferior orbital rim using biologic glue, screw or unabsorbable suture (Mersilene 5.0). The opposite orbits (without implants) represented the control group.
  
  
  RESULTS
  Microscopic signs of inflammatory reaction due to orbitary fixation of the implant were observed with the use of the three methods (biologic glue, screw or unabsorbable suture) (Mersilene 5.0), until six weeks of the postoperatory period.
  
  
  CONCLUSIONS
  Histopathological signs of inflammatory reaction to the implant and to its orbital fixation were observed up to the sixth week, with cyanoacrylate, screw, or unabsorbable suture (Mersilene 5.0), with prevalence of the chronic inflammatory process and cicatricial fibrosis, without statistically significant difference in most of the cases.
authors.affiliation: Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP. elcioroq@ig.com.br
authors.forename: Elcio Roque
authors.initials: ER
authors.lastname: Kleinpaul
authors.forename: Harley Edison Amaral
authors.initials: HE
authors.lastname: Bicas
mesh_terms: D000208:Acute Disease; D000818:Animals; D002908:Chronic Disease; D005260:Female; D005355:Fibrosis / Q000473:pathology; D005549:Foreign-Body Reaction / Q000473:pathology*; D006046:Gold; D008280:Magnetics / Q000009:adverse effects*; D009915:Orbit / Q000473:pathology / Q000601:surgery*; D020273:Orbital Implants / Q000009:adverse effects*; D011817:Rabbits; D013997:Time Factors
chemical_list: D006046:Gold