title: A "crackleware" oesophagus.
abstract: This case report describes a 70 year old woman with excessive diffuse keratinisation of the oral cavity and oesophagus harbouring a squamous cell carcinoma. This excessive diffuse keratinisation of normally non-keratinised squamous epithelium could not be identified in normally non-keratinised epithelia in other parts of the body (the vagina), arguing against a genetic basis for this disorder. The term "crackleware" oesophagus was used to describe this entity, which has not been described previously in the English literature.
authors.affiliation: Department of Surgery, Academic Medical Centre/University of Amsterdam, Suite G4-123, Meibergdreef 9, 1105 AZ, The Netherlands. m.westerterp@AMC.UVA.NL
authors.forename: M
authors.initials: M
authors.lastname: Westerterp
authors.forename: O R C
authors.initials: OR
authors.lastname: Busch
authors.forename: J J G H M
authors.initials: JJ
authors.lastname: Bergman
authors.forename: F J W
authors.initials: FJ
authors.lastname: Ten Kate
authors.forename: J J B
authors.initials: JJ
authors.lastname: van Lanschot
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000628:therapy; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D007642:Keratosis / Q000473:pathology* / Q000628:therapy; D008679:Metaplasia / Q000473:pathology; D011230:Precancerous Conditions / Q000473:pathology* / Q000628:therapy