Catheter-associated bacteremia by Mycobacterium senegalense in Korea.
BACKGROUND
Rapidly growing mycobacteria is recognized as one of the causative agents of catheter-related infections, especially in immunocompromised hosts. To date, however, Mycobacterium senegalense, which was known as the principal pathogen of bovine farcy, has not been reported in human infection.


METHODS
We describe the first case of human infection by M. senegalense, which has caused catheter-related bloodstream infection in a cancer patient in Korea. The microorganism was identified by the 16S rRNA gene, rpoB, and 16S-23S rRNA gene internal transcribed spacer (ITS) sequence analyses.


CONCLUSIONS
Our first report of catheter-associated bacteremia caused by M. senegalense suggests the zoonotic nature of this species and indicates the expansion of mycobacterial species relating to human infection. M. senegalense should be considered as one of the causes of human infections in the clinical practice.
Oh
Won Sup
WS
Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wsoh@smc.samsung.co.kr
Ko
Kwan Soo
KS
Song
Jae-Hoon
JH
Lee
Mi Young
MY
Ryu
Seong Yeol
SY
Taek
Sang
S
Kwon
Ki Tae
KT
Lee
Jang-Ho
JH
Peck
Kyong Ran
KR
Lee
Nam Yong
NY
D016470:Bacteremia / Q000209:etiology* / Q000628:therapy; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007723:Korea; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification* / Q000235:genetics; D009164:Mycobacterium Infections / Q000382:microbiology*; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics
D012336:RNA, Ribosomal, 16S