title: Improvement of surgical antibiotic prophylaxis: a prospective evaluation of personalized antibiotic kits.
abstract: This prospective study compared personalized surgical antibiotic prophylaxis kits (SAPKs) with freely prescribed antibiotics. SAPKs use significantly enhanced national guidelines on surgical antibiotic prophylaxis application (82% vs 41%, P < 0.001), and result in limited errors in terms of antibiotic choice (3% vs 28%, P < 0.001), timing of administration (12% vs 24%, P = 0.003) and prophylaxis duration (1.5% vs 22%, P < 0.001), thereby demonstrating their effectiveness.
authors.affiliation: Department of Anaesthesia, University Hospital of Nice, Nice, France. carles.m@chu-nice.fr
authors.forename: M
authors.initials: M
authors.lastname: Carlès
authors.forename: S
authors.initials: S
authors.lastname: Gindre
authors.forename: N
authors.initials: N
authors.lastname: Aknouch
authors.forename: B
authors.initials: B
authors.lastname: Goubaux
authors.forename: A
authors.initials: A
authors.lastname: Mousnier
authors.forename: M
authors.initials: M
authors.lastname: Raucoules-Aimé
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis / Q000379:methods* / Q000592:standards; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013514:Surgical Procedures, Operative / Q000592:standards*; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents