title: G6PD--an old bottle with new wine.
abstract: The major role of glucose-6-phosphate dehydrogenase (G6PD) is to generate reduced nicotinamide adenine dinucleotide phosphate (NADPH), which is indispensable to reductive metabolism and maintenance of cellular redox homeostasis. Most advances in this field have been made in the pathophysiology of G6PD-deficient erythrocytes and the molecular characterization of different G6PD variants. Recently, numerous studies have shown the importance of G6PD in cell growth, development and disease progression.
authors.affiliation: Graduate Institute of Medical Biotechnology and Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan, Taiwan, ROC.
authors.forename: Hung-Yao
authors.initials: HY
authors.lastname: Ho
authors.forename: Mei-Ling
authors.initials: ML
authors.lastname: Cheng
authors.forename: Daniel Tsun-Yee
authors.initials: DT
authors.lastname: Chiu
mesh_terms: D014644:Genetic Variation; D005954:Glucosephosphate Dehydrogenase / Q000145:classification / Q000235:genetics / Q000502:physiology*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D013624:Taiwan / Q000453:epidemiology
chemical_list: D005954:Glucosephosphate Dehydrogenase