title: Towards an inline reconstruction architecture for micro-CT systems.
abstract: Recent developments in micro-CT have revolutionized the ability to examine in vivo living experimental animal models such as mouse with a spatial resolution less than 50 microm. The main requirements of in vivo imaging for biological researchers are a good spatial resolution, a low dose induced to the animal during the full examination and a reduced acquisition and reconstruction time for screening purposes. We introduce inline acquisition and reconstruction architecture to obtain in real time the 3D attenuation map of the animal fulfilling the three previous requirements. The micro-CT system is based on commercially available x-ray detector and micro-focus x-ray source. The reconstruction architecture is based on a cluster of PCs where a dedicated communication scheme combining serial and parallel treatments is implemented. In order to obtain high performance transmission rate between the detector and the reconstruction architecture, a dedicated data acquisition system is also developed. With the proposed solution, the time required to filter and backproject a projection of 2048 x 2048 pixels inside a volume of 140 mega voxels using the Feldkamp algorithm is similar to 500 ms, the time needed to acquire the same projection.
authors.affiliation: Institut de Recherches Subatomiques, IN2P3-CNRS/ULP, Strasbourg, France. david.brasse@ires.in2p3.fr
authors.forename: David
authors.initials: D
authors.lastname: Brasse
authors.forename: Bernard
authors.initials: B
authors.lastname: Humbert
authors.forename: Carole
authors.initials: C
authors.lastname: Mathelin
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Rio
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Guyonnet
mesh_terms: D000465:Algorithms; D000818:Animals; D021621:Imaging, Three-Dimensional; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D051379:Mice; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed