Primary non-Hodgkin's lymphoma of the spleen presenting as space occupying lesion: a case report and review of literature.
Primary splenic lymphoma (PSL) is rare with a reported incidence of less than 1%. Diffuse large cell pathology has been reported in 22-23% of the cases and is felt to have poor outcome. This study reports a 50 year old male who presented with fever and weakness. He was found to have a mass lesion in the spleen documented by CT scan. A splenectomy was performed which showed non-Hodgkin's lymphoma. Immunohistological studies showed a positivity for CD20 and CD30.
Ambulkar
Indumati
I
Asian Institute of Oncology, S. L. Raheja Hospital, Raheja Rugnalaya Road, Mahim, Mumbai, 400 016, India. ambulkarindumati@rediffmail.com
Kulkarni
Bijal
B
Borges
Anita
A
Jagannath
P
P
Advani
S H
SH
D018951:Antigens, CD20 / Q000378:metabolism; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D012680:Sensitivity and Specificity; D013156:Splenectomy / Q000379:methods; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D014750:Vincristine / Q000627:therapeutic use
D018951:Antigens, CD20; D017730:Ki-1 Antigen; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone