title: Primary non-Hodgkin's lymphoma of the spleen presenting as space occupying lesion: a case report and review of literature.
abstract: Primary splenic lymphoma (PSL) is rare with a reported incidence of less than 1%. Diffuse large cell pathology has been reported in 22-23% of the cases and is felt to have poor outcome. This study reports a 50 year old male who presented with fever and weakness. He was found to have a mass lesion in the spleen documented by CT scan. A splenectomy was performed which showed non-Hodgkin's lymphoma. Immunohistological studies showed a positivity for CD20 and CD30.
authors.affiliation: Asian Institute of Oncology, S. L. Raheja Hospital, Raheja Rugnalaya Road, Mahim, Mumbai, 400 016, India. ambulkarindumati@rediffmail.com
authors.forename: Indumati
authors.initials: I
authors.lastname: Ambulkar
authors.forename: Bijal
authors.initials: B
authors.lastname: Kulkarni
authors.forename: Anita
authors.initials: A
authors.lastname: Borges
authors.forename: P
authors.initials: P
authors.lastname: Jagannath
authors.forename: S H
authors.initials: SH
authors.lastname: Advani
mesh_terms: D018951:Antigens, CD20 / Q000378:metabolism; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D012680:Sensitivity and Specificity; D013156:Splenectomy / Q000379:methods; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D018951:Antigens, CD20; D017730:Ki-1 Antigen; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone