title: Vinyl ketones to allenes: preparation of 1,3-dien-2-yl triflates and their application in Pd-catalyzed reactions with soft nucleophiles.
abstract: [chemical reaction: see text]. A general route of converting alkenyl ketones to functionalized allenes was developed. Substituted 1,3-dien-2-yl triflates, which were prepared from the alkenyl ketones via silyl dienol ethers, were excellent substrates for the palladium-catalyzed reaction with soft nucleophiles giving the multisubstituted allenes in high yields. Comparison between the dienyl triflates and analogous bromodienes in the Pd-catalyzed reaction was studied as well.
authors.affiliation: Catalysis Research Center and Graduate School of Pharmaceutical Sciences, Hokkaido University, and SORST, Japan Science and Technology Agency (JST), Kita-ku, Sapporo 001-0021, Japan. ogasawar@cat.hokudai.ac.jp
authors.forename: Masamichi
authors.initials: M
authors.lastname: Ogasawara
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Ge
authors.forename: Koichi
authors.initials: K
authors.lastname: Uetake
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Takahashi