title: [Local and potential systemic consequences of endodontic root infection].
abstract: In root infections, bacteria are present not only in planktonic cells but also in biofilms, which are more resistant to host defence mechanisms and disinfectans. Apical periodontitis, which may be radiographically undetectable, may develop or persist as a host defence mechanism to prevent the systemic spread of bacteria and their by-products to other sites of the body. The risk of spreading microorganisms and septic emboli is present especially in compromised hosts; furthermore, long-standing inflammation may have systemic effects and affect general health. Effective procedures should be developed to minimize the burden of root infection.
authors.affiliation: Cariologie Endodontologie Pedodontologie van het Academisch Centrum Tandheelkunde Amsterdam. m.wu@acta.nl
authors.forename: M K
authors.initials: MK
authors.lastname: Wu
authors.forename: P R
authors.initials: PR
authors.lastname: Wesselink
mesh_terms: D001424:Bacterial Infections / Q000150:complications* / Q000628:therapy; D018441:Biofilms; D019232:Dental Restoration Failure; D005491:Focal Infection, Dental / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D010485:Periapical Periodontitis / Q000150:complications* / Q000628:therapy; D012389:Root Canal Obturation