[Kidney transplantation improves spermatogenic function in patients with uremia].
OBJECTIVE
To study the changes of testicular spermatogenic function after kidney transplantation.


METHODS
Thirty male patients with uremia underwent kidney transplantation. Semen analyses were made and sperm ultrastructural changes were studied before and after the operation.


RESULTS
Sperm viability, motility and movement velocity were significantly higher in the postoperative group than in the preoperative group [(70.08 +/- 2.86 vs (36.04 +/- 8.01)], [(76.15 +/- 3.75)% vs (39.27 +/- 4.14)%], [(16.80 +/- 1.11) microm/s vs (8.43 +/- 2.01)] micro/s, respectively (P < 0.01). Sertoli cell, acrosome and mitochondria structures inclined to normal after kidney transplantation.


CONCLUSIONS
Kidney transplantation can significantly improve spermatogenic function in patients with uremia.
Yu
Jian-Jun
JJ
Department of Urology, Sixth Peoples Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China. yujj917@163.com
Xu
Yue-Min
YM
Zhang
Hua
H
D000328:Adult; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D013081:Sperm Motility; D013091:Spermatogenesis / Q000502:physiology*; D013094:Spermatozoa / Q000648:ultrastructure; D014511:Uremia / Q000503:physiopathology* / Q000601:surgery