title: Augmentation of osteoporotic bone: effect of pulsed jet-lavage on injection forces, cement distribution, and push-out strength of implants.
abstract: Demographic change in the population leads to higher incidence of fragility fractures. Fracture fixation with standard implants may lead to implant cut-out due to reduced purchase. Augmentation of the bone stock with bone cements might overcome this problem. However, cancellous bone infiltration with the viscous cement dough reveals problems of fat embolism or high pressures during application of the cement. This study investigates the improved quality of bovine cancellous bone augmentation when pulsed jet-lavage is used for fat and marrow removal. Parameters such as injection forces, cement dough distribution through cannulated implants and mechanical strength of the fixation were applied for quantification. Injection of 5 mL of acrylic bone cement required significantly lower forces in the lavaged as compared to the untreated bone (50 N vs. > 300 N). Cement distribution was much more homogeneous and push-out forces significantly higher in the pretreated bone group (8.33 +/- 1.41 kN vs. 1.66 +/- 0.63 kN). The application of pulsed jet-lavage for fat removal prior to acrylic cement augmentation led to much more controlled outcomes of the augmentation. This seems to be a relevant step towards safe and efficient injection of bone cements into cancellous bone structures.
authors.affiliation: AO Development Institute, Clavadelerstrasse, Davos Platz 7270, Switzerland. armando.gisep@aofoundation.org
authors.forename: A
authors.initials: A
authors.lastname: Gisep
authors.forename: R
authors.initials: R
authors.lastname: Curtis
authors.forename: S
authors.initials: S
authors.lastname: Flütsch
authors.forename: N
authors.initials: N
authors.lastname: Suhm
mesh_terms: D001843:Bone Cements; D018786:Bone Substitutes / Q000008:administration & dosage*; D019245:Compressive Strength; D007267:Injections; D010024:Osteoporosis / Q000628:therapy*; D019904:Polymethyl Methacrylate / Q000008:administration & dosage
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D019904:Polymethyl Methacrylate