[Preliminary study on the effects of an artificial liver support system in the treatment of medicamentous liver insufficiency].
OBJECTIVE
To study the effectiveness of an artificial liver support system.


METHODS
Thirty-two patients with medicamentous liver insufficiency were treated with an artificial liver support system in addition to the routine medicinal therapy. Thirty patients treated with routine medicinal therapy only served as controls.


RESULTS
The clinical symptoms (e.g. hepatic encephalopathy) and the laboratory indices (serum total bilirubin and prothrombin time) of the treatment group patients were obviously improved compared with those of the control group patients (P < 0.05). The cure rate and hospitalization days were 90.6% (26/32) and 47 days respectively in the treatment group, and 43.3% (13/30) and 72 days in the control group (P < 0.05).


CONCLUSIONS
Using an artificial liver support system combined with routine medicinal therapy is more effective than using medication alone.
Shang
Jia
J
Henan Provincial People's Hospital, Zhengzhou 450003, China. shangjia666@126.com
Xu
Yun
Y
Yang
Yu-xiu
YX
Jia
Bai-ling
BL
Zhang
He-ping
HP
Jin
Xiu
X
Chen
Ping
P
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000995:Antitubercular Agents / Q000009:adverse effects; D005260:Female; D048550:Hepatic Insufficiency / Q000139:chemically induced / Q000628:therapy*; D006801:Humans; D019164:Liver, Artificial; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents; D000995:Antitubercular Agents