title: [Experience of therapy for sepsis in cancer patients with neutropenia].
abstract: The paper generalizes experience gained in performing 5800 courses of multidrug therapy (MDT) in patients with malignant tumors at various sites, complicated in 68 cases of severe neutropenia (neutrophils less than 500 per microl). Sepsis was diagnosed in 22 cases. With the timely admission of patients with sepsis and neutropenia during complex intensive therapy, their mortality was 22.7%. Emphasis is laid on a role of colony-stimulating factors in the correction of agranulocytosis. Their use decreases the duration of neutropenia, antibiotic therapy, and the length of stay by 1.3 times, as well as the cost of treatment.
authors.forename: A E
authors.initials: AE
authors.lastname: Smirnova
authors.forename: D V
authors.initials: DV
authors.lastname: Lileev
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy*; D009503:Neutropenia / Q000150:complications* / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents