Lupane-triterpenes from Bupleurum flavum.
Two new triterpenoids, lup-20(29)-en-3 alpha, 28-diol (1) and lup-20(29)-en-3 alpha, 28,30-triol (2), have been isolated from aerial parts of Bupleurum flavum, a native plant of the Eastern Mediterranean area (Bulgaria, Greece, and Turkey). Their structures were elucidated by spectral analysis. The known compounds betulin, betulinic acid, jasminol, together with the lignan nemerosin and eight flavonoids (kaempferol, isokaempferide, gossipetin, quercetin, luteolin, isorhamnetin 3-O-beta-D-glucopyranoside, isorhamnetin 3-rutinoside, and rutin) were also characterized.
Pistelli
Luisa
L
Dipartimento di Chimica Bioorganica e Biofarmacia, Universita degli Studi di Pisa, via Bonnano 33, 56126 Pisa, Italy. luipi@farm.unipi.it
Noccioli
Cecilia
C
Giachi
Isa
I
Dimitrova
Burya
B
Gevrenova
Reneta
R
Morelli
Ivano
I
Potenza
Donatella
D
D019661:Apiaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000094062:Betulinic Acid
D014315:Triterpenes; C002503:betulin; D000094062:Betulinic Acid