title: [Endocrine disturbances in circumscribed scleroderma].
abstract: OBJECTIVE
  To evaluate prevalence of endocrine pathology in patients with circumscribed scleroderma (CS), baseline immunopathological alterations in CS patients.
  
  
  METHODS
  Circulating immune complexes were studied by the Digeon method in a total of 70 CS patients (female 52, 74.3%; male 18, 25.7%; age 16 to 70 years).
  
  
  RESULTS
  Circulating immune complexes assay by Digeon detected evident immune imbalance characteristic for metabolic disturbances of the connective tissue and affection of the endocrine system.
  
  
  CONCLUSIONS
  CS patients need a combined examination including endocrinological and immunological tests.
authors.forename: I V
authors.initials: IV
authors.lastname: Khamaganova
authors.forename: A S
authors.initials: AS
authors.lastname: Dvornikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000276:immunology; D004700:Endocrine System Diseases / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000276:immunology* / Q000503:physiopathology; D015995:Prevalence; D012594:Scleroderma, Localized / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology* / Q000503:physiopathology
chemical_list: D000936:Antigen-Antibody Complex