title: Thrombogenesis in experimental microvascular anastomosis.
abstract: A large number of microvascular anastomoses, involving both arteriovenous and artery-artery end-to-side and end-to-end anastomoses, were carried out in the rat to develop a temporal and morphologic profile of thrombogenesis. While excellent patency rates were obtained in purely arterial preparations, significant thrombus formation occurred in the arteriovenous preparations, both at the suture line and more distally in the vein. Factors contributing to thrombogenesis in these microvascular anastomoses are discussed.
authors.affiliation: Neurochirurgische Universitätsklinik, Kantonsspital Zürich, Switzerland.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
authors.forename: M G
authors.initials: MG
authors.lastname: Yasargil
authors.forename: R D
authors.initials: RD
authors.lastname: Smith
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D017536:Carotid Artery, Common / Q000601:surgery*; D004195:Disease Models, Animal; D005500:Follow-Up Studies; D007601:Jugular Veins / Q000601:surgery*; D051381:Rats; D013536:Suture Techniques / Q000009:adverse effects*; D013927:Thrombosis / Q000209:etiology*; D017211:Treatment Failure; D014656:Vascular Surgical Procedures / Q000379:methods*