title: When prostate brachytherapy fails: a case report and discussion.
abstract: For appropriately selected brachytherapy patients, prostate-specific antigen failure is uncommon. Our patient experienced biochemical failure after 125I brachytherapy treatment for low-risk prostate adenocarcinoma. We suggest neoadjuvant/adjuvant hormonal therapy combined with pelvic external-beam radiation therapy as a reasonable salvage treatment. At the 2-year follow-up, he is apparently doing well. With limited data available, salvage management for this situation is presently investigational.
authors.affiliation: University of California, Berkeley, California, USA.
authors.forename: Cigall
authors.initials: C
authors.lastname: Kadoch
authors.forename: Anthony V
authors.initials: AV
authors.lastname: D'Amico
authors.forename: Richard H
authors.initials: RH
authors.lastname: Matthews
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D001918:Brachytherapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D017211:Treatment Failure
chemical_list: D017430:Prostate-Specific Antigen