[Dyslipidemia in the critically ill patient].
Dyslipidemia seen in the critically ill patient is a common disturbance, poorly recognized by physicians in this setting. Shock states, sepsis, multifactorial systemic inflammatory response syndrome and ischemia-reperfusion injury are associated with important metabolic changes that contribute to this disturbance. As a result, the lipid concentration, including cholesterol, high-density lipoproteins and apo-lipoprotein A-I, diminishes. Previous reports correlate the disturbance in lipids with a higher risk of infection, systemic inflammatory response syndrome, multiple organic dysfunction syndrome, and raised mortality. The use of reconstituted high-density lipoprotein may be a therapeutic alternative for the management of this entity.
Carrillo-Esper
Raúl
R
Academia Nacional de Medicina, Asociación Mexicana de Medicina Crítica y Terapia Intensiva, UNAM. seconcapcma@mail.medinet.net.mx
Carvajal-Ramos
Roberto
R
D000818:Animals; D002986:Clinical Trials as Topic; D016638:Critical Illness; D050171:Dyslipidemias / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D006801:Humans