Management of severe hypotony with intravitreal injection of viscoelastic.
OBJECTIVE
To investigate the effect of an intravitreal injection of sodium hyaluronate 1.4% and 2.3% in the treatment of hypotony.


METHODS
Interventional case series.


METHODS
Intravitreal injection of sodium hyaluronate 1.4% was performed to treat persistent hypotony in three eyes after the successful repair of retinal detachment and in one eye with uveitis. Injection of sodium hyaluronate 2.3% was performed in one eye after the successful repair of retinal detachment with removal of silicone oil.


RESULTS
At the last follow-up examination (2-16 months), intraocular pressure increased to at least 5 mm Hg (5-14 mm Hg) in all eyes that had been injected with sodium hyaluronate. Intraocular pressure increased to 38 mm Hg in the eye that had been injected with sodium hyaluronate 2.3% on postoperative day 1 and was 10 mm Hg at three months. Vision improved in all patients.


CONCLUSIONS
Intraocular injection of sodium hyaluronate 1.4 and 2.3% appears to be efficacious in reversing hypotony in some eyes. Functional and structural findings can also improve.
Tosi
Gian Marco
GM
Department of Ophthalmology, Edward S. Harkness Eye Institute, New York Presbyterian Hospital, New York 10032, USA
Schiff
William
W
Barile
Gaetano
G
Yoshida
Norihiko
N
Chang
Stanley
S
D000368:Aged; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects*; D008875:Middle Aged; D015814:Ocular Hypotension / Q000188:drug therapy*; D012163:Retinal Detachment / Q000601:surgery; D014065:Tonometry, Ocular; D015866:Uveitis, Posterior / Q000601:surgery; D014792:Visual Acuity; D014822:Vitreous Body
D006820:Hyaluronic Acid