24-nor-Ursane type triterpenoids from the stems of Rumex japonicus.
Fractionation of an EtOAc-soluble extract of the stems of Rumex japonicus led to the isolation of two new 24-norursane type triterpenoids, 2alpha,3alpha,19alpha-trihydroxy-24-norurs-4(23),12-dien-28-oic acid (1) and 4(R),23-epoxy-2alpha,3alpha,19alpha-trihydroxy-24-norurs-12-en-28-oic acid (2), along with the known compounds myrianthic acid (3), tormentic acid, and emodin. The structures of 1 and 2 were elucidated by spectroscopic methods, particularly by extensive 1D and 2D NMR studies.
Jang
Dae Sik
DS
Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon, Korea.
Kim
Jong Min
JM
Kim
Joo-Hwan
JH
Kim
Jin Sook
JS
D002236:Carbohydrate Conformation; D007723:Korea; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000737:chemistry; D031804:Rumex / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
C507956:2alpha,3alpha,19alpha-trihydroxy-24-norurs-4(23),12-dien-28-oic acid; D014315:Triterpenes