High resolution printing of DNA feature on poly(methyl methacrylate) substrates using supramolecular nano-stamping.
In recent years, a large number of devices based on organic and biological materials have been developed. To scale-up the production of these systems to industrially acceptable standards, there is a need to develop soft-material stamping approaches with the needed resolution, complexity, and versatility. We have recently developed a DNA-based stamping method (supramolecular nano-stamping, SuNS) that has superior resolution and can print multiple molecules at the same time. A similar technique was independently developed by Crooks and co-workers. Here we show that SuNS can be used to efficiently print DNA features on a polymeric substrate (poly(methyl methacrylate), PMMA) with a 40 nm point resolution and a coverage that exceeds 100 mum2. The stamped PMMA substrate was also used as a master to print on a gold substrate. With PMMA being optically clear and electrically insulating, future applications of SuNS to print DNA micro- and nanoarrays are envisioned.
Yu
Arum Amy
AA
Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, 02139, USA.
Savas
Tim
T
Cabrini
Stefano
S
Difabrizio
Enzo
E
Smith
Henry I
HI
Stellacci
Francesco
F
D004277:DNA, Single-Stranded / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D036103:Nanotechnology / Q000379:methods*; D019904:Polymethyl Methacrylate / Q000737:chemistry*
D004277:DNA, Single-Stranded; D019904:Polymethyl Methacrylate