Musculoskeletal ultrasound including definitions for ultrasonographic pathology.
Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joints in a short period of time. However, there are scarce data regarding its validity, reproducibility, and responsiveness to change, making interpretation and comparison of studies difficult. In particular, there are limited data describing standardized scanning methodology and standardized definitions of US pathologies. This article presents the first report from the OMERACT ultrasound special interest group, which has compared US against the criteria of the OMERACT filter. Also proposed for the first time are consensus US definitions for common pathological lesions seen in patients with inflammatory arthritis.
Wakefield
Richard J
RJ
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK. medrjw@leeds.ac.uk
Balint
Peter V
PV
Szkudlarek
Marcin
M
Filippucci
Emilio
E
Backhaus
Marina
M
D'Agostino
Maria-Antonietta
MA
Naredo
Esperanza
E
Iagnocco
Annamaria
A
Schmidt
Wolfgang A
WA
Bruyn
George A W
GA
Bruyn
George
G
Kane
David
D
O'Connor
Philip J
PJ
Manger
Bernhard
B
Joshua
Fred
F
Koski
Juhani
J
Grassi
Walter
W
Lassere
Marissa N D
MN
Swen
Nanno
N
Kainberger
Franz
F
Klauser
Andrea
A
Ostergaard
Mikkel
M
Brown
Andrew K
AK
Machold
Klaus P
KP
Conaghan
Philip G
PG
D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging*; D006801:Humans; D006984:Hypertrophy; D007596:Joints / Q000000981:diagnostic imaging*; D009141:Musculoskeletal System / Q000000981:diagnostic imaging*; D013583:Synovial Membrane / Q000000981:diagnostic imaging; D013585:Synovitis / Q000000981:diagnostic imaging; D013717:Tenosynovitis / Q000000981:diagnostic imaging; D009626:Terminology as Topic; D014463:Ultrasonography