title: Primary endodermal sinus tumor of the cerebellar hemisphere: a case report with review of the literature.
abstract: Primary intracranial endodermal sinus tumors, which have been regarded as a rare histologic subtype, usually arise in the pineal and suprasellar regions and are often associated with components of other germ cell tumors. We report an extremely rare case of pure primary endodermal sinus tumor found in the cerebellar hemisphere. A 3-year-old boy was admitted to our institution because of gait disturbance, vomiting and deteriorated mental state. MR imaging revealed the presence of a round mass with heterogeneous enhancement in the left cerebellar hemisphere. Radical surgical removal of the tumor was performed, followed by adjuvant chemotherapy, consisting of etoposide, carboplatin and bleomycin. The patient has since attended regular follow-ups, without any neurological deficit or signs of recurrence in the 4 years since diagnosis.
authors.affiliation: Department of Neurosurgery, Research Institute of Medical Sciences, Chonnam National University, Hwasun Hospital & Medical School, Gwang-ju, Korea.
authors.forename: Hyo-Cheol
authors.initials: HC
authors.lastname: Cheon
authors.forename: Shin
authors.initials: S
authors.lastname: Jung
authors.forename: Kyung-Sub
authors.initials: KS
authors.lastname: Moon
authors.forename: Min-Cheol
authors.initials: MC
authors.lastname: Lee
authors.forename: In-Young
authors.initials: IY
authors.lastname: Kim
authors.forename: Tae-Young
authors.initials: TY
authors.lastname: Jung
authors.forename: Soo-Han
authors.initials: SH
authors.lastname: Kim
authors.forename: Sam-Suk
authors.initials: SS
authors.lastname: Kang
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D018240:Endodermal Sinus Tumor / Q000473:pathology* / Q000628:therapy*; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures
chemical_list: D001761:Bleomycin; D005047:Etoposide; D016190:Carboplatin