Natural products as angiogenesis modulators.
Cancer remains one of the major causes of death worldwide. Anti-angiogenic therapy is one of the new approaches to anticancer therapy. Out of 22 angiogenesis inhibitors currently under clinical trials there are 11 natural products or were modeled on a natural product parent. This review shows the potential of natural products for the discovery of new anti-angiogenic leads.
El Sayed
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Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monore, Monore, LA 71209, USA. Elsayed@ulm.edu
D020533:Angiogenesis Inhibitors; D000818:Animals; D001688:Biological Products / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D009389:Neovascularization, Pathologic / Q000188:drug therapy / Q000473:pathology
D020533:Angiogenesis Inhibitors; D001688:Biological Products