title: Clinical application of computed tomography for the diagnosis of feline hepatic lipidosis.
abstract: The usefulness of computed tomography (CT) for the diagnosis of feline hepatic lipidosis (FHL) was evaluated. Liver CT number was 54.7+/-5.6 HU (mean+/-SD) in 26 healthy cats. We fast 6 healthy cats for 72 hr to induced FHL experimentally and the cats were assessed by CT and serum biochemical analysis. Liver CT number of the six cats was 53.8+/-3.0 HU before fasting, 46.8+/-2.4 HU after fasting, and 50.2+/-3.6 HU two weeks after restarted feeding. The decreased CT number was associated with the elevation of serum non-esterified fatty acid (NEFA) and beta-hydroxybutyrate levels. These results indicate that measurement of CT number of the liver is an effective procedure for the diagnosis of FHL.
authors.affiliation: Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, Japan.
authors.forename: Momoko
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Chen
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Momoi
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
mesh_terms: D020155:3-Hydroxybutyric Acid / Q000097:blood; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D005230:Fatty Acids, Nonesterified / Q000097:blood; D008064:Lipidoses / Q000175:diagnosis / Q000662:veterinary*; D008107:Liver Diseases / Q000175:diagnosis / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*
chemical_list: D005230:Fatty Acids, Nonesterified; D020155:3-Hydroxybutyric Acid