title: Liver graft volume estimation in 100 living donors: measure twice, cut once.
abstract: Estimation of graft volume (GV) is critical in living donor liver transplantation. This study examines the accuracy of formula-derived GV estimates and compares them to both radiogically-derived estimates and actual measurements. We first compared formula-derived estimates of GV and compared them to actual volumes to provide estimates for both right lobe (RL) and left lateral segment (LLS) GV. We then applied these formulae to a validation cohort. Finally, we evaluated both formula-derived and radiologically-derived estimates by comparing them to actual GV measurements. There is a marginal concordance between formula-derived calculation and GV for RL donors, but the error ratio was lower than for radiologic estimates. In contrast, MRI measurements for LLS grafts demonstrated a lower error ratio than formula-derived estimation. Formula-derived estimates of GV should be routinely used in the initial screening of potential living donors as long as their limitations are appreciated.
authors.affiliation: Division of Organ Transplantation, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Paolo R O
authors.initials: PR
authors.lastname: Salvalaggio
authors.forename: Talia B
authors.initials: TB
authors.lastname: Baker
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Koffron
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Fryer
authors.forename: Lori
authors.initials: L
authors.lastname: Clark
authors.forename: Riccardo A
authors.initials: RA
authors.lastname: Superina
authors.forename: Andres T
authors.initials: AT
authors.lastname: Blei
authors.forename: Albert
authors.initials: A
authors.lastname: Nemcek
authors.forename: Michael M
authors.initials: MM
authors.lastname: Abecassis
mesh_terms: D001699:Biometry; D001830:Body Surface Area; D015331:Cohort Studies; D006801:Humans; D008099:Liver / Q000033:anatomy & histology*; D016031:Liver Transplantation; D019520:Living Donors; D008279:Magnetic Resonance Imaging; D008953:Models, Anatomic; D015203:Reproducibility of Results; D012189:Retrospective Studies