title: [Pharmacological guidelines for the treatment of refractory patients with obsessive-compulsive disorder].
abstract: OCD is a chronic and disabling anxiety disorder, it has a chronic course and few patients achieve true remission. OCD is clearly associated with a significant functional disability. Treatment with selective serotonin reuptake inhibitors (SSRIs) is effective in 40 % to 60 % of patients with OCD, but that leaves a large percentage of patients who are non responsive to treatment. This article will discuss guidelines for the use of SSRIs and novel approaches for managing treatment-refractory patients.
authors.affiliation: Departamento de Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argenitna. etoro@fibertel.com.ar
authors.forename: Esteban
authors.initials: E
authors.lastname: Toro-Martínez
mesh_terms: D004351:Drug Resistance; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors