Latent acute promyelocytic leukemia t(15;17)(q22;q12-21) and sarcoidosis: long-term cohabitation.
The association of sarcoidosis with hematological malignancies is a well-known phenomenon. To our knowledge, we report the first case involving sarcoidosis and acute promyelocytic leukemia (APL) t(15;17)(q22;q12-21). The major interest lies in the chronology of the two diseases: the APL demonstrated an unusual smoldering evolution, suggesting that pre-existing sarcoidosis may have a non-fortuitous immunological impact on leukemic clone proliferation.
Leymarie
V
V
Laboratory of Hematology, Hautepierre University Hospital, avenue Moliere, F-67098 Strasbourg Cedex, France. vincent.leymarie@chru-strasbourg.fr
Galoisy
A C
AC
Falkenrodt
A
A
Natarajan-Ame
S
S
Dufour
P
P
Lessard
M
M