title: [Chronobiology of pulp sensibility in young people].
abstract: OBJECTIVE
  To explore the biological clock of pulp sensibility in young people so as to enrich the theory of pulp-chronobiology and conduce to clinical diagnosis and the treatment of pulposis.
  
  
  METHODS
  40 healthy young volunteers (20 males and 20 females) were examined. Pulp sensibility test was performed using the pulp sensibility tester produced in France. Pulp sensibility reading was obtained at each 4 hours from 8:00 a.m. till next 8:00 a.m., thus there were totally seven time-pints in 24 hours. And the readings were averaged.
  
  
  RESULTS
  The pulp sensibility data of every volunteer were analyzed by methods for cosinor-rhythmometry, and significant difference (P<0.05) was found. The acrophase and bathyphase appeared at 0:00 and 12:00 separately. We did not find significant difference of the mesor, amplitude and phase between young males and females (P> 0.05).
  
  
  CONCLUSIONS
  Circadian rhythm is demonstrated in thepulp sensibility data of young people; the highest pulp sensibility is at 12:00 while the lowest is at 0:00.
authors.affiliation: West China School of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Guo
authors.forename: Zhen
authors.initials: Z
authors.lastname: Xu
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Chen
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Wang
authors.forename: Si-Jing
authors.initials: SJ
authors.lastname: Xie
authors.forename: Qiong
authors.initials: Q
authors.lastname: Zhang
authors.forename: Xue-Dong
authors.initials: XD
authors.lastname: Zhou
mesh_terms: D000328:Adult; D002909:Chronobiology Phenomena; D002940:Circadian Rhythm; D003782:Dental Pulp / Q000294:innervation*; D003791:Dental Pulp Test; D005260:Female; D006801:Humans; D008297:Male; D012677:Sensation; D012737:Sex Factors