title: [Therapeutic effect and safety of transcatheter occlusion of ventricular septal defects in 50 patients].
abstract: OBJECTIVE
  To determine the therapeutic effect and safety of transcatheter closure of ventricular septal defects (VSD) in 50 patients.
  
  
  METHODS
  Fifty patients were diagnosed by transthoracic echocardiography. To perform the operation, transthoracic echocardiography and X ray were used continuously to monitor the procedure. Transthoracic echocardiography and ECG were performed at 1, 3, and 6 months after the operation to evaluate the therapeutic effect.
  
  
  RESULTS
  The VSD diameter ranged from 1.8 to 13.4 (5.54 +/- 2. 75) mm. The successful rate of the operation was 96.0%, and the complication rate of the operation was 16.7%. A 3 month follow-up was completed in 20 patients, and the median left ventricle end-diastolic dimension significantly decreased from (40.20 +/- 8.80) mm to (32.90 +/- 8.36) mm (P < 0.001).
  
  
  CONCLUSIONS
  Transcatheter closure of ventricular septal defects is a good method with a high success rate of placement, fewer complications, and a good occlusion effect.
authors.affiliation: Department of Cardiology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Da-Jun
authors.initials: DJ
authors.lastname: Hu
authors.forename: Chuan-Chang
authors.initials: CC
authors.lastname: Li
authors.forename: Xiao-Qun
authors.initials: XQ
authors.lastname: Pu
authors.forename: Zhao-Fen
authors.initials: ZF
authors.lastname: Zheng
authors.forename: Yang-Cheng
authors.initials: YC
authors.lastname: Zhao
authors.forename: Tian-Lun
authors.initials: TL
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D021721:Balloon Occlusion / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D006328:Cardiac Catheterization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D016896:Treatment Outcome