Multivalent, bifunctional dendrimers prepared by click chemistry.
Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.
Wu
Peng
P
The Scripps Research Institute, Department of Chemistry, La Jolla, CA 92037, USA.
Malkoch
Michael
M
Hunt
Jasmine N
JN
Vestberg
Robert
R
Kaltgrad
Eiton
E
Finn
M G
MG
Fokin
Valery V
VV
Sharpless
K Barry
KB
Hawker
Craig J
CJ
D000114:Acetylene / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D050091:Dendrimers; D000114:Acetylene