title: [Recurrent Impetigo Herpetiformis: successfully managed with ciclosporine. Report of one case].
abstract: Impetigo Herpetiformis is a high-risk gestational skin disease that represents a risk for both the mother and offspring. Its management is based on multisystemic support and maternal steroid therapy. When these measures are insufficient to control the disease, the association of ciclosporine to the treatment has been proposed. We report a 24 year-old woman with a 16 weeks pregnancy, that presented with Impetigo Herpetiformis. The disease was refractory to the use of steroids, the patient had a metabolic decompensation and a dehydration with electrolyte imbalance. Therefore, treatment with ciclosporine was initiated and a rapid regression of the lesions was observed. Gestation was maintained, with a good perinatal outcome.
authors.affiliation: Departamento de Obstetricia y Ginecología, Hospital Clínico, Universidad de Chile. evaldes@ns.hospital.uchile.cl
authors.forename: Enrique
authors.initials: E
authors.lastname: Valdés
authors.forename: Tatiana
authors.initials: T
authors.lastname: Núñez
authors.forename: Daniel
authors.initials: D
authors.lastname: Pedraza
authors.forename: Hernán
authors.initials: H
authors.lastname: Muñoz
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000627:therapeutic use*; D003874:Dermatitis Herpetiformis / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007169:Impetigo / Q000188:drug therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D012008:Recurrence
chemical_list: D003879:Dermatologic Agents; D016572:Cyclosporine