Development of contrast enhancement after long-term observation of a dysembryoplastic neuroepithelial tumor.
Dysembryoplastic neuroepithelial tumors (DNET) are usually benign lesions that arise in cortical regions and are discovered after new onset of seizure. These lesions have many different imaging characteristics. We report a patient with a presumed low-grade medial temporal lobe lesion that was followed for many years without any change in size or imaging characteristics. This previously non-enhancing tumor evolved to become contrast enhanced on routine imaging without apparent tumor growth. The patient underwent surgery, and the pathology was confirmed as a DNET with no atypical changes. This case demonstrates the potential that DNETs may exhibit a changing MRI pattern over time. Natural history, imaging characteristics, and management are reviewed.
Jensen
Randy L
RL
Department of Neurosurgery, University of Utah, Salt Lake City, Utah 84132-2303, USA. randy.jensen@hsc.utah.edu
Caamano
Eryn
E
Jensen
Elizabeth M
EM
Couldwell
William T
WT
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018302:Neoplasms, Neuroepithelial / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D011856:Radiographic Image Enhancement; D012640:Seizures / Q000209:etiology
D014408:Biomarkers, Tumor; D003287:Contrast Media; D005682:Gadolinium