title: In vivo organ mass of Korean adults obtained from whole-body magnetic resonance data.
abstract: In vivo organ mass of the Korean adult, male and female were presented for the purpose of radiation protection. A total of 121 healthy volunteers (66 males and 55 females), whose body dimensions were close to that of average Korean adults, were recruited for this study. Whole-body magnetic resonance (MR) images were obtained, and contours of 15 organs (brain, eye, gall bladder, heart, kidney, liver, lung, pancreas, stomach, spleen, testes, thymus, thyroid, urinary bladder and uterus) and 9 bones (femur, tibia + fibula, humerus, radius + ulna, pelvis, cervical spine, thoracic and lumber spine, skull and clavicle) were segmented for organ volume rendering by anatomists using commercial software. Organ and bone masses were calculated by multiplying the Asian reference densities of the corresponding organs and bones by the measured volumes. The resulting organ and bone masses were compared with those of the International Commission of Radiological Protection (ICRP) and the Asian reference data. Significantly large standard deviation was shown in the moving organs of the respiratory and circulatory systems and in the alimentary and urogenital organs that are variable in volume in a single person. Gall bladder and pancreas showed unique Korean organ masses compared with those of ICRP and the Asian reference adults. Different from anatomical data based on autopsy, the in vivo volume and mass in this study can more exactly describe the organ volume of a living human subject for radiation protection. A larger sample size would be required for obtaining statistically more reliable results. It is also needed to establish the reference organ mass of younger age groups for which it is difficult to recruit volunteers and to immobilise the subjects for long-time MR scanning. At present, the data from this study will contribute to the establishment of a Korean reference database.
authors.affiliation: Department of Nuclear Engineering, Hanyang University, 17 Haengdang, Seongdong, Seoul, Korea.
authors.forename: S
authors.initials: S
authors.lastname: Park
authors.forename: J K
authors.initials: JK
authors.lastname: Lee
authors.forename: J I
authors.initials: JI
authors.lastname: Kim
authors.forename: Y J
authors.initials: YJ
authors.lastname: Lee
authors.forename: Y K
authors.initials: YK
authors.lastname: Lim
authors.forename: C S
authors.initials: CS
authors.lastname: Kim
authors.forename: C
authors.initials: C
authors.lastname: Lee
mesh_terms: D000328:Adult; D000886:Anthropometry / Q000379:methods*; D001824:Body Constitution / Q000502:physiology*; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D007723:Korea / Q000453:epidemiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009929:Organ Size / Q000502:physiology*; D009928:Organ Specificity; D011835:Radiation Protection / Q000379:methods / Q000592:standards; D012016:Reference Values; D014781:Viscera / Q000502:physiology*; D051598:Whole Body Imaging / Q000379:methods*