title: Influence of supplemental high molecular weight pullulan or gamma-cyclodextrin on ileal and total tract nutrient digestibility, fecal characteristics, and microbial populations in the dog.
abstract: This study was conducted to determine if supplemental pullulan and gamma-cyclodextrin affect canine nutrient digestibility, microbial populations, and fecal characteristics. Ileal cannulated dogs were fed a commercial diet, and treatments were administered daily in a 5 x 5 Latin square design: (i) no supplement; (ii) 2 g pullulan; (iii) 4 g pullulan; (iv) 2 g gamma-cyclodextrin; (v) 4 g gamma-cyclodextrin. Ileal and fecal samples were collected the last 4 d of each 14-d period. Increasing pullulan tended (p < 0.10) to linearly increase ileal bifidobacteria and lactobacilli and quadratically increase fecal lactobacilli. A similar response was noted in ileal bifidobacteria and lactobacilli with gamma-cyclodextrin. Gamma-Cyclodextrin resulted in a quadratic decrease (p < 0.05) in fecal Clostridium perfringens. Increasing pullulan linearly increased (p < 0.05) fecal score, while gamma-cyclodextrin resulted in a linear decrease (p < 0.05). Pullulan and gamma-cyclodextrin supplementation may have beneficial effects on the microbial ecology of dogs.
authors.affiliation: Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA.
authors.forename: Julie K
authors.initials: JK
authors.lastname: Spears
authors.forename: Lisa K
authors.initials: LK
authors.lastname: Karr-Lilienthal
authors.forename: George C
authors.initials: GC
authors.lastname: Fahey
mesh_terms: D000818:Animals; D001644:Bifidobacterium / Q000254:growth & development* / Q000378:metabolism; D003016:Clostridium perfringens / Q000254:growth & development; D004063:Digestion; D004285:Dogs / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000382:microbiology; D005260:Female; D005936:Glucans / Q000008:administration & dosage* / Q000378:metabolism; D007082:Ileum / Q000382:microbiology; D007778:Lactobacillus / Q000254:growth & development* / Q000378:metabolism; D008970:Molecular Weight; D019936:Probiotics; D011897:Random Allocation; D047408:gamma-Cyclodextrins / Q000008:administration & dosage* / Q000378:metabolism
chemical_list: D005936:Glucans; D047408:gamma-Cyclodextrins; C009109:pullulan