title: Nasal septal perforation: a novel clinical manifestation of systemic juvenile idiopathic arthritis/adult onset Still's disease.
abstract: Nasal septal perforation has been well recognized in patients with various rheumatic diseases. To our knowledge, this condition has not been reported in children with systemic juvenile idiopathic arthritis (SJIA) or patients with adult onset Still's disease (AOSD). We describe 3 patients with persistent SJIA/AOSD who developed nasal septal perforation during the course of their disease. As illustrated by these cases, nasal septal perforation may develop as a rare complication of SJIA/AOSD and can be considered as part of the clinical spectrum of the disease. In one case the nasal septal perforation was associated with vasculitis.
authors.affiliation: Division of Rheumatology, Department of Otolaryngology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
authors.forename: Tadej
authors.initials: T
authors.lastname: Avcin
authors.forename: Earl D
authors.initials: ED
authors.lastname: Silverman
authors.forename: Vito
authors.initials: V
authors.lastname: Forte
authors.forename: Rayfel
authors.initials: R
authors.lastname: Schneider
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009300:Nasal Septum / Q000473:pathology; D009668:Nose Diseases / Q000209:etiology* / Q000473:pathology; D016706:Still's Disease, Adult-Onset / Q000150:complications*; D014657:Vasculitis / Q000150:complications