title: Surgical management of metastatic spine tumors.
abstract: Recent advances in diagnostic tests and radiologic imaging, and the development of novel chemotherapeutic agents and radiation methods have greatly altered the treatment options in patients who have spinal tumors. Improvements in fundamental understanding of the mechanisms of bone metastases, developments in spinal instrumentation, and recent introduction of recombinant bone morphogenetic proteins for spinal reconstruction offer promising strategies in selected patients. Clear applications of the fundamental surgical oncology still apply to spinal tumors. This article considers recent advances in management of the metastatic tumors to the spine.
authors.affiliation: Department of Orthopaedic Surgery, University of California at Davis Medical Center, Sacramento, 95817, USA. safdar.khan@ucdmc.ucdavis.edu
authors.forename: Safdar N
authors.initials: SN
authors.lastname: Khan
authors.forename: Rakesh
authors.initials: R
authors.lastname: Donthineni
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009367:Neoplasm Staging; D019637:Orthopedic Procedures / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000379:methods; D018570:Risk Assessment; D013123:Spinal Fusion / Q000379:methods; D013125:Spinal Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome