Antidermatophytic and bacterial activity of mimosine.
Mimosine, a non-protein aromatic amino acid was tested at 100, 50 and 25 microg/mL on some human pathogenic bacteria and fungi. Mimosine exhibited total lethality towards Trichophyton tonsurans and Trichophyton rubrum at 100 microg/mL. Among the tested bacteria Staphylococcus aureus was inhibited to a larger extent than the other bacteria. The studies revealed mimosine to be potent against fungi rather than bacteria. This study reports the effect of mimosine on dermatophytes for the first time.
Anitha
R
R
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai-600 025, India. anitha_rajasekar@hotmail.com
Jayavelu
S
S
Murugesan
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects; D003881:Dermatomycoses / Q000188:drug therapy; D007887:Fabaceae / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D008898:Mimosine / Q000494:pharmacology* / Q000627:therapeutic use; D013211:Staphylococcus aureus / Q000187:drug effects*; D014249:Trichophyton / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D008898:Mimosine