Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis.
The cell envelopes of actinomycetes contain lipidated macroamphiphiles, of which the most extensively characterised are the lipoarabinomannans of mycobacteria and related bacteria. We have investigated the mycolic acid-containing actinomycete Gordonia bronchialis and identified the presence of a lipoarabinomannan-like lipoglycan. The extraction and purification procedures recovered a second amphiphilic fraction with properties suggesting a phosphatidylinositol mannoside, consistent with studies of other Gordonia species.
Garton
Natalie J
NJ
Department of Infection, Immunity and Inflammation, Leicester University, Medical Sciences Building, University Road, PO Box 138, LE1 9HN, Leicester, UK.
Sutcliffe
Iain C
IC
D005227:Fatty Acids / Q000032:analysis; D033601:Gordonia Bacterium / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000302:isolation & purification*; D019308:Palmitic Acid / Q000032:analysis; D013229:Stearic Acids / Q000032:analysis
D005227:Fatty Acids; D008070:Lipopolysaccharides; D013229:Stearic Acids; C050016:lipoarabinomannan; D019308:Palmitic Acid; C031183:stearic acid; C026082:tuberculostearic acid; C013102:margaric acid