[Effects of sildenafil on erectile dysfunction in the aged men with diabetes].
OBJECTIVE
To evaluate the efficacy and safety of sildenafil on erectile dysfunction in the aged men with diabetes.


METHODS
One hundred and ten patients aged 55 years old above with type I or II diabetes and a minimum 3-month history of ED were studied. Patients were instructed to take one dose of their treatment orally at any time before anticipated sexual activity. Changes from baseline in mean scores on the erectile function domain of the International index of Erectile Function and changes from baseline in the proportion of "yes" responses to question 2, and 3, of the Sexual Encounter Profile were coprimary outcome measures.


RESULTS
Treatment with sildenafil significantly improved all primary efficacy variables.


CONCLUSIONS
Sildenafil therapy significantly enhanced erectile function and was well tolerated by men with diabetes and ED.
He
Zhan-Ju
ZJ
Department of Urology, Peking University, Institute of Urology, First Hospital, Beijing 100034, China. hezhanju@263.net
Jin
Jie
J
Zhang
Kai
K
D000368:Aged; D048909:Diabetes Complications / Q000188:drug therapy*; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate