title: Lupane-triterpenes from Bupleurum flavum.
abstract: Two new triterpenoids, lup-20(29)-en-3 alpha, 28-diol (1) and lup-20(29)-en-3 alpha, 28,30-triol (2), have been isolated from aerial parts of Bupleurum flavum, a native plant of the Eastern Mediterranean area (Bulgaria, Greece, and Turkey). Their structures were elucidated by spectral analysis. The known compounds betulin, betulinic acid, jasminol, together with the lignan nemerosin and eight flavonoids (kaempferol, isokaempferide, gossipetin, quercetin, luteolin, isorhamnetin 3-O-beta-D-glucopyranoside, isorhamnetin 3-rutinoside, and rutin) were also characterized.
authors.affiliation: Dipartimento di Chimica Bioorganica e Biofarmacia, Universita degli Studi di Pisa, via Bonnano 33, 56126 Pisa, Italy. luipi@farm.unipi.it
authors.forename: Luisa
authors.initials: L
authors.lastname: Pistelli
authors.forename: Cecilia
authors.initials: C
authors.lastname: Noccioli
authors.forename: Isa
authors.initials: I
authors.lastname: Giachi
authors.forename: Burya
authors.initials: B
authors.lastname: Dimitrova
authors.forename: Reneta
authors.initials: R
authors.lastname: Gevrenova
authors.forename: Ivano
authors.initials: I
authors.lastname: Morelli
authors.forename: Donatella
authors.initials: D
authors.lastname: Potenza
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000094062:Betulinic Acid
chemical_list: D014315:Triterpenes; C002503:betulin; D000094062:Betulinic Acid