[The application of basic fibroblast growth factor in tendon tissue engineering].
OBJECTIVE
To review the recent researches of basic fibroblast growth factor (bFGF) in tendon tissue engineering.


METHODS
Recent original related literature was extensively reviewed and analyzed.


RESULTS
bFGF played an important role in establishing standard tendon tissue engineering cell lines, inducing the compound and analysis of extracellular matrix, enhancing interactions between cells and extracellular matrix and accelerating tissue engineering materials' neovascularization.


CONCLUSIONS
The progresses in increasing endogenetic bFGF expression, controlling the release of exogenous bFGF and improving the bio-utilization of bFGF has laid foundation for wider use of bFGF in tendon tissue engineering.
Hao
Peng
P
Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
Xiang
Zhou
Z
Yang
Zhiming
Z
D000818:Animals; D002460:Cell Line; D016222:Fibroblast Growth Factor 2 / Q000494:pharmacology*; D006801:Humans; D013710:Tendons; D023822:Tissue Engineering; D054457:Tissue Scaffolds
D016222:Fibroblast Growth Factor 2