Autoimmune hepatitis and multiple sclerosis: a coincidental association?
In the present study we report, as part of a large multiple sclerosis (MS) cohort (1800 patients), three cases of untreated patients who developed autoimmune hepatitis (AIH). The prevalence of AIH in the general population is about 0.0169% and seems to be higher in our MS cohort (0.17%). We suggest that a liver biopsy should systematically be performed in untreated MS patients with a sustained increase of liver enzyme.
de Seze
J
J
Department of Neurology, University of Lille, France. j-deseze@chru-lille.fr
Canva-Delcambre
V
V
Fajardy
I
I
Delalande
S
S
Stojkovic
T
T
Godet
E
E
Vermersch
P
P
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000328:Adult; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D019693:Hepatitis, Autoimmune / Q000453:epidemiology*; D006801:Humans; D016899:Interferon-beta / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000453:epidemiology*; D015995:Prevalence; D011379:Prognosis
D000276:Adjuvants, Immunologic; D016899:Interferon-beta