title: [Prediction of 2-year outcome by combining TIMI myocardial perfusion grading with sum ST segment resolution in patients with acute myocardial infarction].
abstract: OBJECTIVE
  To evaluate the value of combining TIMI myocardial perfusion (TMP) grading with sum ST segment resolution (sumSTR) in prediction of the 2-year outcome and heart function in patients with acute myocardial infarction (AMI) after emergency percutaneous intervention (PCI).
  
  
  METHODS
  Seventy-seven consecutive patients of AMI with elevated ST segment, 62 males and 15 females, aged 63 +/- 12 (30-91), underwent PCI. TMP grading was used in combination of electrocardiography to calculate the sumSTR so as to evaluate the effect of myocardial reperfusion. The patients with TMP grade 2-3 and sumSTR > or = 30% were included in the group of better perfusion, and those with the TMP grade 0-1 and sumSTR < 30% were included in the group of lower perfusion. The cardiac events, including death, reinfarction, revascularization, angina pectoris, and heart failure were recorded. The left ventricular end-diastolic dimension (LVEDD) and left ventricular ejection fraction (LVEF) were measured by echocardiography 72 hours and 2 years after the PCI.
  
  
  RESULTS
  There were 37 patients in the lower perfusion group and 39 patients in the better perfusion group. Cos regression showed that TMP grade 0-1 associated with sumSTR < 30% was an independent factor for 2-year cardiac events (RR = 13.186, 95% CI 2.149 - 80.917, P = 0.005). The LVEDD 2 years after PCI was 60 mm +/- 4 mm, significantly higher than that 72 hours after PCI (53 mm +/- 4 mm. P < 0.01) in the lower perfusion group. The LVEDD increased by 7.1 mm +/- 1.9 mm two years after PCI in the lower perfusion group, significantly more than that in the better perfusion group (1.5 mm +/- 1.2 mm, P < 0.01). The myocardial perfusion after PCI was closely correlated with the extent of heart function improvement 2 years after (chi(2) = 50.58, P < 0.01).
  
  
  CONCLUSIONS
  TMP grading combined with sumSTR helps predict the 2-year outcome and heart function in the patients with AMI after emergency PCI.
authors.affiliation: Department of Cardiology, Third Hospital of Peking University, Beijing 100083, China.
authors.forename: Fei
authors.initials: F
authors.lastname: She
authors.forename: Fu-chun
authors.initials: FC
authors.lastname: Zhang
authors.forename: Fang-jing
authors.initials: FJ
authors.lastname: Wei
authors.forename: Jie-ming
authors.initials: JM
authors.lastname: Mao
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Guo
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Niu
authors.forename: Xin-heng
authors.initials: XH
authors.lastname: Feng
authors.forename: Yi-ming
authors.initials: YM
authors.lastname: Zhao
authors.forename: Jing-qiao
authors.initials: JQ
authors.lastname: Lü
authors.forename: Jing-xuan
authors.initials: JX
authors.lastname: Guo
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003326:Coronary Circulation; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis