Dietary fat and breast cancer in Saudi Arabia: a case-control study.
A case-control study investigated the association between dietary fat and breast cancer in Saudi Arabian women attending a specialist hospital in Riyadh. Women with breast carcinoma (n= 499) newly diagnosed between 1996-2002, and control women (n = 498) randomly selected from patients' attendants and relatives, completed a food frequency questionnaire. Serum levels of triglycerides and total cholesterol were measured. A significant positive association was found between risk of breast cancer and intake of fats, protein and calories. Adjusted odds ratios for the highest quartile of intake versus the lowest were 2.43 for saturated fat, 2.25 for animal protein, 2.12 for polyunsaturated fat, 1.88 for cholesterol and 2.69 for total energy from dietary intake. For serum triglycerides the adjusted odds ratio was 2.16 for the highest quartile.
Alothaimeen
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Department of Biostatistics, Epidemiology and Scientific Computing, Nutrition Research, Riyadh, Saudi Arabia.
Ezzat
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A
Mohamed
G
G
Muammar
T
T
Al-Madouj
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D000328:Adult; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D002784:Cholesterol / Q000008:administration & dosage / Q000097:blood; D004034:Diet Surveys; D004041:Dietary Fats / Q000009:adverse effects* / Q000032:analysis; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D005227:Fatty Acids / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage; D005247:Feeding Behavior; D005260:Female; D019456:Health Transition; D006782:Hospitals, Special; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D015999:Multivariate Analysis; D016017:Odds Ratio; D011159:Population Surveillance; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000008:administration & dosage / Q000097:blood
D004041:Dietary Fats; D004044:Dietary Proteins; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D014280:Triglycerides; D002784:Cholesterol