title: [Clinical value of ultrasound guided transperineal prostate biopsy in detecting prostate cancer].
abstract: OBJECTIVE
  To report our experience of ultrasound guided transperineal 6-core prostate biopsy (UG6CPB) in the diagnosis of prostate cancer (PCa).
  
  
  METHODS
  In a prospective study, we performed UG6CPB in 104 suspected PCa patients with tPSA more than 4 microg/L and analysed the positive rate and complications of the diagnostic approach.
  
  
  RESULTS
  PCa was detected in 24 of the 104 patients (23%), with low grade Gleason 2 to 4 in 3 cases (12.5%), intermediate grade Gleason 5 to 7 in 15 (62.5%) and high grade Gleason 8 to 10 in the remaining 6 (25%). Complications included temporary hematuria in 5 patients (4.8%), mild postbiopsy perineal discomfort in 5 (4.8%) and fever in 4 (3.8%). TPSA > or =10 microg/L, fPSA > or = 2 microg/L, fPSA/tPSA < 0.16, PSAD > or = 0.2 and prostate volume < 40 ml were the significant influencing factors of biopsy positive rate (P < 0.05).
  
  
  CONCLUSIONS
  UG6CPB is an exact and a safe way of detecting PCa.
authors.affiliation: Department of Urology, Beijing Jishuitan Hospital, Beijing 100035, China. lee_gz99@sohu.com
authors.forename: Gui-Zhong
authors.initials: GZ
authors.lastname: Li
authors.forename: Liu
authors.initials: L
authors.lastname: Liu
authors.forename: Guang-Lin
authors.initials: GL
authors.lastname: Huang
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.forename: Bing
authors.initials: B
authors.lastname: Yan
authors.forename: Yan
authors.initials: Y
authors.lastname: Gao
authors.forename: Fei
authors.initials: F
authors.lastname: Luo
authors.forename: Ning
authors.initials: N
authors.lastname: Liu
authors.forename: Jian-Wei
authors.initials: JW
authors.lastname: Wang
authors.forename: Li-Bo
authors.initials: LB
authors.lastname: Man
authors.forename: Feng
authors.initials: F
authors.lastname: He
authors.forename: Hai
authors.initials: H
authors.lastname: Wang
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D008297:Male; D010502:Perineum; D011446:Prospective Studies; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen