title: Vaginal involvement in a woman with Darier's disease: a case report.
abstract: BACKGROUND
  Involvement of the female genital tract by Darier's disease, an unusual genodermatosis, is uncommon, and the manifestation of the disease in a cervicovaginal smear is exceptionally rare.
  
  
  METHODS
  A 39-year-old woman had an abnormal Pap smear caused by involvement of the female genital tract by Darier's disease. Cytologic examination showed features consistent with a low grade squamous intraepithelial lesion, but during a biopsy it was found to be vaginal involvement by Darier's disease.
  
  
  CONCLUSIONS
  The correct interpretation of cytologic findings is not possible when the diagnosis of Darier's disease is not known since a low grade squamous intraepithelial lesion cannot be ruled out. This case underlines the importance of knowing the patient's medical histoiy in any moment of medical attention.
authors.affiliation: Department of Pathology, Clinical University Hospital of Santiago de Compostela, Spain. jsuarezp@usc.es
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Suárez-Peñaranda
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Antúnez
authors.forename: Emilio
authors.initials: E
authors.lastname: Del Rio
authors.forename: Veiga H
authors.initials: VH
authors.lastname: Vázquez
authors.forename: Alejandro
authors.initials: A
authors.lastname: Novo Domínguez
mesh_terms: D017255:Acitretin / Q000627:therapeutic use; D000328:Adult; D002584:Cervix Uteri / Q000473:pathology; D007644:Darier Disease / Q000150:complications* / Q000235:genetics / Q000473:pathology*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007633:Keratins / Q000378:metabolism; D007641:Keratolytic Agents / Q000627:therapeutic use; D065006:Papanicolaou Test; D012008:Recurrence; D012867:Skin / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014621:Vagina / Q000473:pathology*; D014623:Vaginal Diseases / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000473:pathology
chemical_list: D007641:Keratolytic Agents; D007633:Keratins; D017255:Acitretin