[The effect of vilon (Lys-Glu) on 1.2-dimethylhydrazine-induced neoplasia].
The influence of vilon (Lys-Glu) on 1.2-dimethylhydrazine-induced neoplasia in mice has been studied. After treatment with 10 microg/kg, tumors developed in 14.3% which survived until first tumor detection (46 weeks) while, in control group, tumors occurred in 60%. Vilon-related inhibition of preneoplastic alterations in the kidneys was reported.
Pliss
G B
GB
Mel'nikov
A S
AS
Malinin
V V
VV
Khavinson
V Kh
VKh
D019813:1,2-Dimethylhydrazine; D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D004151:Dipeptides / Q000494:pharmacology*; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000473:pathology* / Q000517:prevention & control*; D051379:Mice; D011230:Precancerous Conditions / Q000139:chemically induced / Q000473:pathology* / Q000517:prevention & control*
D016588:Anticarcinogenic Agents; D004151:Dipeptides; C415909:lysylglutamic acid; D019813:1,2-Dimethylhydrazine