title: Fifteen-year series of skin-sparing mastectomy for stage 0 to 2 breast cancer.
abstract: BACKGROUND
  In 1989, skin-sparing mastectomy started at a number of breast centers in the United States because of an increasing demand for immediate reconstruction and a desire for better cosmetic outcomes.
  
  
  METHODS
  To ensure the safety of this new approach, we have reviewed the personal series of a single surgeon using a standardized skin-sparing technique during 1989 to 2004.
  
  
  RESULTS
  Skin-sparing mastectomy with immediate reconstruction was performed on 225 patients, and standard mastectomy was performed on 1,022 patients. The age distribution was 8 years younger on average in the reconstructed group. The average follow-up for each group was 49 months. The local recurrence for each group was 1.7% and 1.5% (P > .80). The regional recurrence was 3.8% and 3.9% (P > .80). The average time to local recurrence was similar in each group (33.1 and 32.6 months, P > .80).
  
  
  CONCLUSIONS
  A skin-sparing mastectomy does not change the local, regional, or systemic risk to breast cancer patients.
authors.affiliation: OU Breast Institute, 920 S. L. Young Blvd, Suite 2290, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
authors.forename: Roy M
authors.initials: RM
authors.lastname: Greenway
authors.forename: Leon
authors.initials: L
authors.lastname: Schlossberg
authors.forename: William C
authors.initials: WC
authors.lastname: Dooley
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D062109:Dermatologic Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D013524:Surgical Flaps; D013997:Time Factors; D016896:Treatment Outcome