title: Case study: data management strategies in an integrated pathway tool.
abstract: This paper describes the development strategies for an integrated tool to support scientists in the creative exploration of data relating to biochemical pathways. The multiple user groups, diverse functionalities, and many types and sources of data demanded a flexible yet coherent approach. This paper summarises the software requirements and the implied modules and functions, and focuses on the design decisions relevant to the representation, management and flow of data. Finally, several case studies in the use of the software are described and evaluated, and recommendations are made for future work.
authors.affiliation: LION bioscience AG, Heidelberg, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Bernauer
authors.forename: David
authors.initials: D
authors.lastname: Croft
authors.forename: Paul
authors.initials: P
authors.lastname: Gardina
authors.forename: Eric
authors.initials: E
authors.lastname: Minch
authors.forename: Manuel
authors.initials: M
authors.lastname: de Rinaldis
authors.forename: Ivayla
authors.initials: I
authors.lastname: Vatcheva
mesh_terms: D000818:Animals; D003198:Computer Simulation; D003628:Database Management Systems; D016208:Databases, Factual; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D008954:Models, Biological; D020543:Proteome / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D018511:Systems Integration
chemical_list: D020543:Proteome