title: Evaluation of the subjects' response to antipsychotics questionnaire.
abstract: The present study reports on the development of a new self-administered instrument to assess patients' responses to antipsychotic medication. The Subjects' Response to Antipsychotics (SRA) Questionnaire is a 74-item instrument with eight scales (Recovery, Weight Gain, Sexual Anhedonia, Sedation, Affective Flattening, Extrapyramidal Side-Effects, Diminished Sociability and Increased Sleep), and a total adverse responses score including additional items. Psychometric aspects were examined in a study of 320 inpatients and outpatients showing good internal consistency, reproducibility and external validity. Concordance with other instruments claiming to measure the subjective response is low, suggesting that the instruments measure different concepts. The SRA Questionnaire appears to be a reliable and efficient way of measuring patients' subjective responses to antipsychotic medication.
authors.affiliation: Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
authors.forename: Hugo A
authors.initials: HA
authors.lastname: Wolters
authors.forename: Rikus
authors.initials: R
authors.lastname: Knegtering
authors.forename: Durk
authors.initials: D
authors.lastname: Wiersma
authors.forename: Robert J
authors.initials: RJ
authors.lastname: van den Bosch
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001294:Attitude to Health; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011618:Psychotic Disorders / Q000188:drug therapy*; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents