Unprecedented reactivity in the Morita-Baylis-Hillman reaction; intramolecular alpha-alkylation of enones using saturated alkyl halides.
sp3 Hybridized electrophiles, never before used in the organomediated Morita-Baylis-Hillman reaction, now facilitate the formation of five- and six-membered enone cycloalkylation products.
Krafft
Marie E
ME
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, 32306-4390, USA. mek@chem.fsu.edu
Seibert
Kimberly A
KA
Haxell
Thomas F N
TF
Hirosawa
Chitaru
C