Teaching resources. Regulation of complexes by cytoskeletal elements: integrins serve as force transducers linking mechanical stimuli and biochemical signals.
This Teaching Resource provides a summary and slides derived from a lecture on the integrin family members and the downstream signaling pathways they activate; it is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture focuses on the capacity of integrins to serve as mechanotransducers, with particular emphasis on signaling mechanisms downstream of integrins.
Felsenfeld
Dan P
DP
Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA. dan.felsenfeld@mssm.edu
D000818:Animals; D001296:Audiovisual Aids; D001695:Biology / Q000193:education*; D003599:Cytoskeleton / Q000502:physiology*; D004500:Education, Graduate; D006801:Humans; D016023:Integrins / Q000502:physiology*; D046912:Multiprotein Complexes / Q000502:physiology*; D010812:Physical Stimulation; D015398:Signal Transduction / Q000502:physiology*; D013314:Stress, Mechanical; D014159:Transducers
D016023:Integrins; D046912:Multiprotein Complexes