[Endocrine disturbances in circumscribed scleroderma].
OBJECTIVE
To evaluate prevalence of endocrine pathology in patients with circumscribed scleroderma (CS), baseline immunopathological alterations in CS patients.


METHODS
Circulating immune complexes were studied by the Digeon method in a total of 70 CS patients (female 52, 74.3%; male 18, 25.7%; age 16 to 70 years).


RESULTS
Circulating immune complexes assay by Digeon detected evident immune imbalance characteristic for metabolic disturbances of the connective tissue and affection of the endocrine system.


CONCLUSIONS
CS patients need a combined examination including endocrinological and immunological tests.
Khamaganova
I V
IV
Dvornikov
A S
AS
D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000276:immunology; D004700:Endocrine System Diseases / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000276:immunology* / Q000503:physiopathology; D015995:Prevalence; D012594:Scleroderma, Localized / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology* / Q000503:physiopathology
D000936:Antigen-Antibody Complex