title: [Cryotherapy of the resection edge after hepatectomy of colorectal liver metastases].
abstract: Obtaining a one-centimeter negative margin is an important factor in preventing disease recurrence after surgery for hepatic tumors. Cryotherapy of the resected edge has been used to achieve optimal margin clearance in cases in which the alternative would be an extended high-risk liver resection. As a concrete method, cryotherapy was delivered with a liquid nitrogen based compact system (CRY-AC, Brymill Co., USA). The resection edge with involved or inadequate resection margins was ablated directly by using the flat probe for 3 minutes per 1 place. Between 2002 and present, a total of 14 patients with colorectal liver metastases underwent edge cryotherapy. Although there was no hemorrhage from the stump, postoperative leak of the bile and stump recurrence were recognized in each patient. Since cryotherapy has features that make the vascular difficult to be damaged, the complication was not recognized in the patient with exposed vascular in the resected edge. By extending the follow-up period, we want to examine whether the edge recurrence could be controlled or not.
authors.affiliation: Dept. of Gastrointestinal Surgery, Toho University School of Medicine, Omori Hospital.
authors.forename: Masashi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Hironori
authors.initials: H
authors.lastname: Kaneko
authors.forename: Wataru
authors.initials: W
authors.lastname: Takita
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Otsuka
authors.forename: Masaru
authors.initials: M
authors.lastname: Tsuchiya
authors.forename: Akira
authors.initials: A
authors.lastname: Tamura
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Maeda
authors.forename: Yoko
authors.initials: Y
authors.lastname: Oshima
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Teramoto
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D003452:Cryosurgery / Q000379:methods; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D011183:Postoperative Complications