Potential new avenues of treatment for chronic rhinosinusitis: an anti-inflammatory approach.
Chronic rhinosinusitis is a complex disease process, one that is characterized by much more than just infection. Until its pathophysiology is understood fully, truly definitive therapy may remain elusive. As this underlying inflammatory process begins to unravel, however, new avenues of therapy will begin to emerge. This article discusses some of these new therapies and provides some clues as to where future avenues may go.
Statham
Melissa McCarty
MM
Department of Otolaryngology, University of Cincinnati, 231 Albert Sabin Way, M.L. 528, Cincinnati, OH 45267, USA.
Seiden
Allen
A
D000281:Administration, Intranasal; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007167:Immunotherapy; D018836:Inflammation Mediators / Q000276:immunology; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D018942:Macrolides / Q000627:therapeutic use; D012220:Rhinitis / Q000188:drug therapy* / Q000503:physiopathology; D012852:Sinusitis / Q000188:drug therapy* / Q000503:physiopathology
D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D007155:Immunologic Factors; D018836:Inflammation Mediators; D020024:Leukotriene Antagonists; D018942:Macrolides