title: Cytogenetic investigations in four canine lymphomas.
abstract: Four cases of canine lymphoma are presented, including histological examination and cytogenetic investigation. The first case showed a derivative chromosome 13, the second case showed a clonal trisomy 8 and the third case showed a complex karyotype with a clonal trisomy 13 and additional clonal trisomies of the chromosomes 20, 30 and 37, as well as a non-clonal tetrasomy 9. Case four showed a single trisomy 2. Comparing these results with human hematopoietic malignancies, there are notable similarities between both species.
authors.affiliation: Center for Human Genetics, University of Bremen, Leobener Strasse ZHG, 28359 Bremen, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Winkler
authors.forename: Hugo
authors.initials: H
authors.lastname: Murua Escobar
authors.forename: Nicola
authors.initials: N
authors.lastname: Reimann-Berg
authors.forename: Jörn
authors.initials: J
authors.lastname: Bullerdiek
authors.forename: Ingo
authors.initials: I
authors.lastname: Nolte
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics* / Q000662:veterinary*; D008297:Male; D014314:Trisomy