Integrating behavioral and social science research into microbicide clinical trials: challenges and opportunities.
It has been argued that rigid thinking about the types and progression of research needed to evaluate health promotion interventions has stymied the process by which research is translated to action. This argument is particularly salient in the field of HIV/AIDS prevention. We examined microbicide research and identified challenges that obstruct the integration of clinical trial and behavioral and social science research, thereby reinforcing linear programs of research. We found that behavioral and social science research can both support microbicide clinical trial performance and anticipate the information most needed for a rapid and successful introduction of future microbicide products.
Tolley
Elizabeth E
EE
Family Health International, 2224 East NC 54, Durham, NC 27713, USA. btolley@fhi.org
Severy
Lawrence J
LJ
D000287:Administration, Topical; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D035841:Behavioral Research; D035843:Biomedical Research / Q000379:methods*; D002986:Clinical Trials as Topic / Q000379:methods*; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D012107:Research Design; D012942:Social Sciences
D000890:Anti-Infective Agents