Toscana virus central nervous system infections in southern Italy.
Toscana virus was detected by reverse transcription-nested PCR in 5.6% of cerebrospinal fluid (CSF) samples from patients with meningitis and encephalitis during the summer in southern Italy. The central nervous system infections were associated with young adults and with a substantially benign clinical course. Presenting features and CSF findings are also discussed in the present report.
Di Nicuolo
Giuseppe
G
Laboratory of Virology, D. Cotugno Hospital, Via G. Quagliariello 54, Naples 80131, Italy. giuseppe.dinicuolo@ospedalecotugno.it
Pagliano
Pasquale
P
Battisti
Sonia
S
Starace
Maria
M
Mininni
Vera
V
Attanasio
Vittorio
V
Faella
Francesco Saverio
FS
D000293:Adolescent; D000328:Adult; D002555:Cerebrospinal Fluid / Q000821:virology; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000821:virology; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000821:virology; D010217:Phlebotomus Fever / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D029301:Sandfly fever Naples virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*