Mechanisms of resistance to beta-lactams in some common Gram-negative bacteria causing nosocomial infections.
Gram-negative bacilli remain major killers of hospitalized patients and continue to evolve new resistance mechanisms. This review describes the mechanisms of resistance to beta-lactam antibiotics from those Gram-negative pathogens most often isolated from nosocomial infections.
Suárez
Carlos José
CJ
Bacterial Resistance Line, CIDEIM (International Center for Medical Research and Training), Cali, Colombia. carlosj_suarez@cideim.org.co
Lolans
Karen
K
Villegas
Maria Virginia
MV
Quinn
John P
JP
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy* / Q000235:genetics; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000235:genetics; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D018440:beta-Lactam Resistance / Q000187:drug effects / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D047090:beta-Lactams