Cytogenetic investigations in four canine lymphomas.
Four cases of canine lymphoma are presented, including histological examination and cytogenetic investigation. The first case showed a derivative chromosome 13, the second case showed a clonal trisomy 8 and the third case showed a complex karyotype with a clonal trisomy 13 and additional clonal trisomies of the chromosomes 20, 30 and 37, as well as a non-clonal tetrasomy 9. Case four showed a single trisomy 2. Comparing these results with human hematopoietic malignancies, there are notable similarities between both species.
Winkler
Susanne
S
Center for Human Genetics, University of Bremen, Leobener Strasse ZHG, 28359 Bremen, Germany.
Murua Escobar
Hugo
H
Reimann-Berg
Nicola
N
Bullerdiek
Jörn
J
Nolte
Ingo
I
D000818:Animals; D002869:Chromosome Aberrations; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics* / Q000662:veterinary*; D008297:Male; D014314:Trisomy