title: Wobenzym in treatment of recurrent obstructive bronchitis in children.
abstract: A total of 27 patients with recurrent obstructive bronchitis (at least 3 episodes of obstructive bronchitis per year) of 5-15 years of age were studied. Serum IgE level (by ELISA method) and pulmonary function indices were determined together with the full clinical examination. The systemic enzyme preparation Wobenzym was administered with a dosage of 1 tablet for 6 kg weight. Wobenzym was administered for 3 months. Effectiveness of the treatment was assessed by special questionnaire, in which existence of the main symptoms were recorded. Analysis of the data, obtained after treatment, demonstrated decrease of the Daily Symptom Score and an increase of Symptom Free Days, as well as an improvement in spirometric indices (FVC, FEV, PEF). According to these data, it was concluded, that systemic enzyme preparation Wobenzym should be used as a supporting measure in combination treatment of recurrent obstructive bronchitis.
authors.affiliation: Tbilisi State Medical University; M. Guramishvili Pediatric Clinic, Tbilisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Lanchava
authors.forename: K
authors.initials: K
authors.lastname: Nemsadze
authors.forename: I
authors.initials: I
authors.lastname: Chkhaidze
authors.forename: E
authors.initials: E
authors.lastname: Kandelaki
authors.forename: N
authors.initials: N
authors.lastname: Nareklishvili
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D029481:Bronchitis, Chronic / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006867:Hydrolases / Q000627:therapeutic use*; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*; D012008:Recurrence; D012431:Rutin / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D004338:Drug Combinations; D012431:Rutin; C023295:Wobenzym; D006867:Hydrolases