title: Favorable outcome of pneumonia due to Panton-Valentine leukocidin-producing Staphylococcus aureus associated with hematogenous origin and absence of flu-like illness.
abstract: Reported here is what is believed to be the first case of community-acquired pneumonia caused by a Panton-Valentine leukocidin-producing strain of Staphylococcus aureus in Spain. Although lung infections caused by S. aureus strains carrying this powerful leukocidin gene are associated with necrotizing pneumonia and high mortality, the previously healthy 28-year-old male reported here experienced a good clinical course and recovery. It is thought that the hematogenous origin of the infection, the patient's lack of any previous respiratory viral infection and prompt initiation of therapy may explain the satisfactory evolution in this case.
authors.affiliation: Servei d'Anàlisis Clíniques-Microbiologia, Hospital General de l'Hospitalet, CSI, Avinguda Josep Molins 29-41, L'Hospitalet de Llobregat, Barcelona, 08906, Spain. carlesmicro@gmail.com
authors.forename: C
authors.initials: C
authors.lastname: Alonso-Tarrés
authors.forename: M L
authors.initials: ML
authors.lastname: Villegas
authors.forename: F J
authors.initials: FJ
authors.lastname: de Gispert
authors.forename: M C
authors.initials: MC
authors.lastname: Cortés-Lletget
authors.forename: A
authors.initials: A
authors.lastname: Rovira Plarromaní
authors.forename: J
authors.initials: J
authors.lastname: Etienne
mesh_terms: D000328:Adult; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D001427:Bacterial Toxins; D017714:Community-Acquired Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D005098:Exotoxins / Q000302:isolation & purification; D006801:Humans; D007251:Influenza, Human / Q000175:diagnosis; D007956:Leukocidins / Q000302:isolation & purification; D008297:Male; D011023:Pneumonia, Staphylococcal / Q000188:drug therapy / Q000382:microbiology*; D013030:Spain; D013211:Staphylococcus aureus / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin