Prognostic relevance of large-platelet counts in patients with immune thrombocytopenic purpura.
In this preliminary study, the value of different platelet parameters, measured by the ADVIA120 Analyzer, in predicting the immediate response to intravenous immunoglobulin or intravenous anti-RhoD was assessed in 31 patients with immune thrombocytopenic purpura. The number of large platelets pre-treatment was the only independent predictor of the 24 hour-platelet increase.
Michel
Marc
M
Kreidel
Felix
F
Chapman
E Sabrinah
ES
Zelmanovic
David
D
Bussel
James B
JB
D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000648:ultrastructure*; D048429:Cell Size; D002648:Child; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007518:Isoantibodies / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D010976:Platelet Count; D011379:Prognosis; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood* / Q000401:mortality / Q000601:surgery / Q000628:therapy; D018029:Rho(D) Immune Globulin; D013156:Splenectomy
D016756:Immunoglobulins, Intravenous; D007518:Isoantibodies; C061961:RHO(D) antibody; D018029:Rho(D) Immune Globulin