title: Deep corneal neovascularization after implantation with intrastromal corneal ring segments.
abstract: OBJECTIVE
  To demonstrate the development of deep corneal neovascularization after intrastromal corneal ring segment (ICRS) implantation, and to demonstrate complete regression after treatment with surgical removal and anti-inflammatory therapy.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  A 29-year-old man developed deep stromal neovascularization after ICRS implantation for post-laser-assisted in situ keratomileusis ectasia that was not associated with the surgical wound.
  
  
  RESULTS
  After surgical removal of the ICRS and treatment with topical prednisolone acetate 1.0% and cyclosporine A 1.0%, complete vessel regression occurred in 2 weeks.
  
  
  CONCLUSIONS
  ICRS can induce deep corneal neovascularization that is not associated with the surgical wound. Surgical removal of the intrastromal ring and treatment with topical anti-inflammatory agents can induce vessel regression.
authors.affiliation: Anterior Segment Division, Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. atorbaq@health.net.sa
authors.forename: Abdullah
authors.initials: A
authors.lastname: Al-Torbak
authors.forename: Abdullrahman
authors.initials: A
authors.lastname: Al-Amri
authors.forename: Michael D
authors.initials: MD
authors.lastname: Wagoner
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003316:Corneal Diseases / Q000601:surgery; D016510:Corneal Neovascularization / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D003319:Corneal Stroma / Q000098:blood supply / Q000601:surgery*; D016572:Cyclosporine / Q000627:therapeutic use; D020878:Device Removal; D004108:Dilatation, Pathologic / Q000601:surgery; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000009:adverse effects*
chemical_list: D016572:Cyclosporine; C009935:prednisolone acetate; D011239:Prednisolone