title: Homologous recombination is promoted by translesion polymerase poleta.
abstract: Two new studies provide in vivo ( [this issue of Molecular Cell]) and in vitro ( [this issue of Molecular Cell]) evidence that poleta functions to extend 3' strands exchanged during homologous recombination and raise the issue of how TLS polymerases are selected onto different substrates.
authors.affiliation: Gene Regulation and Chromosome Biology Laboratory, NCI-Frederick, P.O. Box B, Maryland 21702, USA.
authors.forename: Alison J
authors.initials: AJ
authors.lastname: Rattray
authors.forename: Jeffrey N
authors.initials: JN
authors.lastname: Strathern
mesh_terms: D000818:Animals; D004247:DNA / Q000235:genetics / Q000378:metabolism*; D004260:DNA Repair; D004259:DNA-Directed DNA Polymerase / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D008957:Models, Genetic; D051135:Rad51 Recombinase / Q000378:metabolism; D011995:Recombination, Genetic; D012689:Sequence Homology, Nucleic Acid; D000099270:Y-Family DNA Polymerases
chemical_list: D004247:DNA; D004259:DNA-Directed DNA Polymerase; D051135:Rad51 Recombinase; C112338:Rad30 protein; D000099270:Y-Family DNA Polymerases