Toxin conjugate therapy of cancer.
Standard approaches to the treatment of malignancies include surgery, chemotherapy, and radiation. More recently, with understanding of these processes in molecular detail, biologics have become another important aspect of treatment. Conjugate toxins are biologics that combine a potent toxin with a peptide that will target cancer cells with minimal damage to normal tissues. This review will detail examples of these conjugate toxins and their targeted malignancies.
Wong
Lucas
L
Division of Hematology/Oncology, Scott & White Hospital, Temple, TX 76508, USA.
Suh
Dick Y
DY
Frankel
Arthur E
AE
D001427:Bacterial Toxins / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006801:Humans; D000922:Immunotoxins / Q000627:therapeutic use*; D009369:Neoplasms / Q000276:immunology / Q000628:therapy
D001427:Bacterial Toxins; D000922:Immunotoxins