title: Bulbar conjunctival staining in contact lens wearers and non lens wearers and its association with symptomatology.
abstract: It has become increasingly apparent that bulbar conjunctival anomalies are associated with dry eye symptoms. Lissamine green (LG) and sodium fluorescein (FL) conjunctival staining were assessed in 102 soft contact lens wearers and 79 non contact lens wearers. Conjunctival staining was increased in symptomatic patients. Both LG and FL staining were discriminating factors for symptomatic non lens wearers (>or=grade 1.5, p<0.001). Only LG staining could discriminate symptomatic from asymptomatic lens wearers (>or=grade 1.0, p=0.007). This analysis confirms the involvement of the conjunctiva in dry eye symptomatology. While both stains are useful, LG shows greater specificity for symptomatic subjects, particularly in contact lens wearer. It is recommended that the examination of patients complaining of dry eyes, in particular contact lens wearing patients include as routine, the examination of the conjunctiva with lissamine green.
authors.affiliation: Optometric Technology Group, 42 Vauxhall Bridge Road, Pimlico, London SW 1V 2RX, UK. mguillon@otg.co.uk
authors.forename: Michel
authors.initials: M
authors.lastname: Guillon
authors.forename: Cecile
authors.initials: C
authors.lastname: Maissa
mesh_terms: D000328:Adult; D004396:Coloring Agents; D003229:Conjunctival Diseases / Q000175:diagnosis* / Q000209:etiology; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects; D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D019793:Fluorescein; D006801:Humans; D008086:Lissamine Green Dyes; D008297:Male; D009883:Ophthalmic Solutions; D013194:Staining and Labeling / Q000379:methods
chemical_list: D004396:Coloring Agents; D008086:Lissamine Green Dyes; D009883:Ophthalmic Solutions; D019793:Fluorescein