title: [Behavior of intraocular pressure according to cardiorespiratory and hemodynamic effects induced by desflurane in dogs subjected to experimental hypovolemia].
abstract: OBJECTIVE
  To observe the behavior of intraocular pressure according to the cardiopulmonary and hemodynamic effects induced by desflurane in dogs subjected to experimental hypovolemia.
  
  
  METHODS
  Eighteen healthy male and female mongrel dogs, weighing between 10 and 15 kg were used. Hypovolemia was induced by withdrawal of 40 ml blood/kg body weight. Then anesthesia was induced with desflurane by mask until tracheal intubation was permitted. Intraocular pressure was measured with applanation tonometry. Heart rate, cardiac output, mean arterial pressure, central venous pressure, end-tidal concentration of CO2 and respiratory rate were recorded. Parameters were registered after animal instrumentation and before any procedure in the awake dogs (T0), fifteen minutes after experimental hemorrhage induction (T45), and after thirty minutes of desflurane anesthesia (T75).
  
  
  RESULTS
  Intraocular pressure presented direct correlation only with pressure and end-tidal concentration of CO2.
  
  
  CONCLUSIONS
  It was not possible to establish a correlation between alterations of mean arterial pressure and central venous pressure and intraocular pressure and there was a direct relationship between values of intraocular pressure and values of exhaled CO2.
authors.affiliation: Departamento de Clínica e Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, SP. iviact@ig.com.br
authors.forename: Ivia Carmem
authors.initials: IC
authors.lastname: Talieri
authors.forename: Cristiane dos Santos
authors.initials: Cdos S
authors.lastname: Honsho
authors.forename: Newton
authors.initials: N
authors.lastname: Nunes
authors.forename: Almir Pereira de
authors.initials: AP
authors.lastname: Souza
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Duque
mesh_terms: D000704:Analysis of Variance; D000758:Anesthesia / Q000662:veterinary; D018685:Anesthetics, Inhalation / Q000627:therapeutic use*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D002302:Cardiac Output / Q000187:drug effects / Q000502:physiology; D000077335:Desflurane; D004285:Dogs / Q000601:surgery*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D020896:Hypovolemia / Q000503:physiopathology* / Q000662:veterinary; D007429:Intraocular Pressure / Q000187:drug effects* / Q000502:physiology; D007530:Isoflurane / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male
chemical_list: D018685:Anesthetics, Inhalation; D000077335:Desflurane; D007530:Isoflurane