title: [Effect of tobacco smoking, respiratory symptoms and asthma on spirometry among adults attending a check-up clinic in Mexico City].
abstract: OBJECTIVE
  To evaluate the effect of tobacco smoking, respiratory symptoms, and asthma on lung function among Mexican adults who were evaluated during a medical exam in a private health clinic.
  
  
  METHODS
  Reference prediction equations were generated for spirometry parameters [forced vital capacity (FVC), forced expired volume in one second (FEV1) and FEV1/FVC] based on multiple linear regression models. The effect of tobacco smoking, respiratory symptoms and asthma on these equations were explored.
  
  
  RESULTS
  Spirometry tests were performed on 919 subjects from 14 to 86 years of age. Asthma decreased FVC and FEV1 in men with a R2 change <1%. Respiratory symptoms decreased the FEV1/FVC ratio in both sexes. Tobacco smoking was associated with a significant reduction in FEV in women.
  
  
  CONCLUSIONS
  Asthma lightly reduced lung function in males while tobacco smoking decreased FEV, particularly in females.
authors.affiliation: Departamentos de Fisiología Respiratoria y de Investigación en Tabaquismo, Instituto Nacional de Enfermedades Respiratorias, México, DF México.
authors.forename: Justino
authors.initials: J
authors.lastname: Regalado-Pineda
authors.forename: Alejandro
authors.initials: A
authors.lastname: Gómez-Gómez
authors.forename: Javier
authors.initials: J
authors.lastname: Ramírez-Acosta
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Vázquez-García
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000503:physiopathology*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D012129:Respiratory Function Tests; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects*; D013147:Spirometry; D014505:Urban Population; D014797:Vital Capacity