[Comparative assessment of the quality of life of reproductive age patients with endometriosis depending on the method of treatment].
The purpose of the study was to investigate the influence of endometriosis as well as certain widely-spread methods of its conservative hormonal and surgical treatment on the quality of life of the patients in reproductive age. 546 twenty to forty years old women have been examined: 371 patients with the first time diagnosed endometriosis (I group), 64 -- after conservative hormonal therapy (II group), 111 -- after radical surgery (III group) and 30 healthy women (control group). All women operated for endometriosis were assessed to determine the quality of life by the following scores: "unsatisfactory" -- 0 point, "satisfactory" -- 1 point, excellent -- 2 points. The average index of quality of life among all subjects was equal to 0,5+/-0,62 points (from 1,0+/-0,69 in the group of patients after one-sided ovariectomy or adnexectomy to 0,3+/-0,45 -- in patients after double adnexectomy with hysterectomy) that was 7,8 times (p<0,001) and 2,6 times less than the given indices in the control group and in the untreated patients correspondingly. So, endometriosis in reproductive age significantly deteriorates the quality of life of the patients in comparison with healthy women. This quality can't be fully restored by any of the analyzed methods of conservative hormonal treatment, radical surgery leads to its further significant deterioration requiring thus to continue searching for the most optimal approaches to the treatment and rehabilitation of patients with endometriosis in the reproductive age.
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D000328:Adult; D004715:Endometriosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D014591:Uterine Diseases / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*