title: Diabetes and percutaneous coronary intervention in the setting of an acute coronary syndrome.
abstract: Diabetes mellitus has reached epidemic proportions worldwide. Patients with diabetes are at increased risk for acute coronary syndromes, and these syndromes lead to frequent morbidity and cardiovascular mortality. Emerging adjunctive pharmacological strategies coupled with the drug-eluting stent platform have resulted in improved adverse event rates for this high-risk group. This review will concentrate on the historical data associated with acute coronary syndromes in diabetes mellitus, focusing on revascularisation, drug-eluting stents and antiplatelet therapies.
authors.affiliation: Mid America Heart Institute, Saint Luke's Hospital, Kansas City, Missouri 64111, USA.
authors.forename: David M
authors.initials: DM
authors.lastname: Safley
authors.forename: Steven P
authors.initials: SP
authors.lastname: Marso
mesh_terms: D000208:Acute Disease; D015906:Angioplasty, Balloon, Coronary; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000188:drug therapy / Q000628:therapy*; D023903:Coronary Restenosis / Q000209:etiology / Q000517:prevention & control*; D048909:Diabetes Complications / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D017239:Paclitaxel / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D058919:Purinergic P2 Receptor Antagonists; D016032:Randomized Controlled Trials as Topic; D020123:Sirolimus / Q000627:therapeutic use; D015607:Stents / Q000706:statistics & numerical data; D013577:Syndrome
chemical_list: D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D058919:Purinergic P2 Receptor Antagonists; D017239:Paclitaxel; D020123:Sirolimus