title: Effects of ischemic training on leg exercise endurance.
abstract: This study tested whether ischemic exercise training (Tr(IS+EX)) would increase endurance of ischemic (Ex(IS)) and ramp exercise (Ex(RA)) knee-extension tests more than exercise training (Tr(EX)) alone. Ten healthy subjects performed pre- and posttraining tests with each leg. For Ex(RA), after subjects warmed up, a weight was added each minute until they were exhausted. Ex(IS) was similar, but after warm-up, we inflated a thigh cuff to 150 mmHg instead of adding weights. One leg was chosen for Tr(IS+EX) (cuff inflated to 150 mmHg during exercise) and the other for Tr(EX), both with a small weight on each leg, four to six times per daily session for 3 to 5 min each, 5 days per week for 6 weeks. Ex(IS) duration increased 120% more (p = 0.002) in the Tr(IS+EX) leg than in the contralateral Tr(EX) leg, whereas Ex(RA) duration increased only 16% (nonsignificant). Tr(IS+EX )and Tr(EX) significantly attenuated the ventilation increase (ergoreflex) during Ex(IS). TheO(2) debt for Ex(IS )was significantly lower and systolic blood pressure recovery was faster after Tr(IS+EX) than after Tr(EX). Heart rate recovery after Ex(RA )andEx(IS )was faster after Tr(IS+EX). Apparently, Tr(IS+EX) with low-intensity resistance increases exercise endurance and attenuates the ergoreflex and therefore may be a useful tool to increase regional muscle endurance to improve systemic exercise capacity in patients.
authors.affiliation: Cardiology Section, Department of Veterans Affairs Medical Center, Albuquerque, NM 87108, USA. loeppky@unm.edu
authors.forename: Jack A
authors.initials: JA
authors.lastname: Loeppky
authors.forename: Burke
authors.initials: B
authors.lastname: Gurney
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Milton V
authors.initials: MV
authors.lastname: Icenogle
mesh_terms: D000328:Adult; D000368:Aged; D004576:Electromyography; D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology*; D007537:Isometric Contraction / Q000502:physiology; D007719:Knee Joint / Q000502:physiology; D007866:Leg / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000502:physiology*; D010101:Oxygen Consumption / Q000502:physiology; D010806:Physical Education and Training; D010809:Physical Fitness / Q000502:physiology; D012016:Reference Values; D016474:Weight-Bearing / Q000502:physiology; D014938:Work Capacity Evaluation