[Place of thyroglobulin antibodies assay in laboratory diagnostic of autoimmune thyroid diseases].
Tyroglobulin and thyroid peroxidase antibodies have been estimated in patients with thyroid autoimmune diseases. In a group of 109 patients with Hashimoto's thyroidities 85.53% and 78.89% were positive for Tyroglobulin antibodies and anti-TPO antibodies respectively. The anti-Tg antibodies has not been detected in 14.67% and anti-TPO in 21.1% patients. Both antibodies have not been detected in 1.83% of patients. In a group of 79 patients with Graves' disease 62.02 and 91.13% were positive for anti-Tg and anti-TPO antibodies respectively. The anti-Tg antibodies has not been detected in 37.97% and anti-TPO in 8.66% patients. Both antibodies have not been detected in one patients with exophtalmos (1.26%). Our results indicate that anti-tyroglobulin antibodies should be estimated only in patients suspected for thyroid autoimmune disease and negative for thyroid peroxidase antibodies.
Lastrzebska-Bohaterewicz
Ewa
E
Department of Clinical Biochemistry, Medical Center of Postgraduate Education, 01-813 Warsaw, Marymoncka 99, Poland.
Wojciechowska
Wanda
W
Gardas
Andrzej
A
D006111:Graves Disease / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D050031:Hashimoto Disease / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D007124:Immunoenzyme Techniques / Q000379:methods; D018828:Immunoglobulins, Thyroid-Stimulating / Q000097:blood* / Q000276:immunology; D007753:Laboratories; D011044:Poland; D012680:Sensitivity and Specificity; D013954:Thyroglobulin / Q000097:blood* / Q000276:immunology
D018828:Immunoglobulins, Thyroid-Stimulating; D013954:Thyroglobulin