title: Esophageal cancer epidemiology in blacks and whites: racial and gender disparities in incidence, mortality, survival rates and histology.
abstract: BACKGROUND
  Esophageal cancer rate disparities are pronounced for blacks and whites. This study presents black-white esophageal cancer incidence, mortality, relative survival rates, histology and trends for two five-year time periods--1991-1995 and 1996-2000--and for the time period 1991-2000.
  
  
  METHODS
  The study used data from the National Cancer Institute's population-based Surveillance Epidemiology End Results (SEER) program with submission dates 1991-2000. Age-adjusted incidence, mortality, relative survival rates and histology for esophageal carcinoma were calculated for nine SEER cancer registries for 1991-2000. Rates were analyzed by race and gender for changes over specified time periods.
  
  
  RESULTS
  Esophageal cancer age-adjusted incidence of blacks was about twice that of whites (8.63 vs. 4.39/100,000, p < 0.05). Age-adjusted mortality for blacks, although showing a declining trend, was nearly twice that of whites (7.79 vs. 3.96, p < 0.05). Although survival was poor for all groups, it was significantly poorer in blacks than in whites. Squamous cell carcinoma was more commonly diagnosed in blacks and white females, whereas adenocarcinoma was more common among white males (p < 0.001).
  
  
  CONCLUSIONS
  Racial disparities in esophageal cancer incidence, mortality, survival and histology exist. Survival rates from this disease have not significantly improved over the decade. These data support the need for advances in prevention, early detection biomarker research and research on new, more effective treatment modalities for this disease.
authors.affiliation: Department of Internal Medicine, Office of Policy and Planning, University of Maryland School of Medicine, Baltimore, MD 21201, USA. cbaquet@som.umaryland.edu
authors.forename: Claudia R
authors.initials: CR
authors.lastname: Baquet
authors.forename: Patricia
authors.initials: P
authors.lastname: Commiskey
authors.forename: Kelly
authors.initials: K
authors.lastname: Mack
authors.forename: Stephen
authors.initials: S
authors.lastname: Meltzer
authors.forename: Shiraz I
authors.initials: SI
authors.lastname: Mishra
mesh_terms: D000230:Adenocarcinoma / Q000208:ethnology; D044383:Black People / Q000706:statistics & numerical data*; D002294:Carcinoma, Squamous Cell / Q000208:ethnology; D004938:Esophageal Neoplasms / Q000208:ethnology* / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D017678:Sex Distribution; D016019:Survival Analysis; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data*; D001741:Black or African American