title: [Evolution of severe pediatric malaria in Togo between 2000 and 2002].
abstract: The aim of this study was to analyse the clinical and evolutive aspects of severe malaria in hospitalised children in 2000, 2001, and 2002 in Togo. The study included 361 children in the pediatrics department of Lomé-Tokoin University hospital. All them received a 10% dextrose infusion, then an infusion of quinine or intramuscular artemether. Malaria accounted for 4.37% of all hospitalizations. Children aged 1 to 5 years were more affected (69.53%). The most frequent clinical forms were anaemia (55.7%) followed by cerebral manifestations. The frequency of hemoglobinuria increased (17.2%) as well as renal failure (3%) compared to previous years. Thirty-five children died (9.7%). Most of them presented with anaemia, neurological manifestations, or respiratory distress. Neurological sequels were present in 2.2% of patients.
authors.affiliation: Service de pédiatrie, CHU-Tokoin, BP 8881, Lomé, Togo. adgbadoe@yahoo.fr
authors.forename: A D
authors.initials: AD
authors.lastname: Gbadoé
authors.forename: M
authors.initials: M
authors.lastname: Kini-Caussi
authors.forename: S
authors.initials: S
authors.lastname: Koffi
authors.forename: H
authors.initials: H
authors.lastname: Traoré
authors.forename: D Y
authors.initials: DY
authors.lastname: Atakouma
authors.forename: K
authors.initials: K
authors.lastname: Tatagan-Agbi
authors.forename: J K
authors.initials: JK
authors.lastname: Assimadi
mesh_terms: D000740:Anemia / Q000453:epidemiology / Q000209:etiology; D000962:Antimalarials / Q000627:therapeutic use; D002675:Child, Preschool; D003128:Coma / Q000453:epidemiology / Q000209:etiology; D018450:Disease Progression; D006456:Hemoglobinuria / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007223:Infant; D008288:Malaria / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality; D016779:Malaria, Cerebral / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D015995:Prevalence; D051437:Renal Insufficiency / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D012640:Seizures / Q000453:epidemiology / Q000209:etiology; D014037:Togo / Q000453:epidemiology
chemical_list: D000962:Antimalarials