title: [Effects of acupuncture at Neiguan (PC 6) on human brain functional imaging in different functional states].
abstract: OBJECTIVE
  To study on effects of acupuncture at a same point at physiological or pathological state on brain functional imaging.
  
  
  METHODS
  Electroacupuncture was given at Neiguan (PC 6) of the healthy senile persons (normal group) and the patients of Alzheimer's disease (AD group), and they were scanned on a 1.5 T MRI scanner and the data of functional magnetic resonance imaging (fMRI) were analyzed by Statistical Parametric Mapping (SPM99). The functional imaging of different brain regions were obtained from both the healthy group and the AD group.
  
  
  RESULTS
  Both the frontal lobe and the temporal lobe were activated in varying degrees by electroacupuncture at Neiguan (PC 6) in the healthy group. However, the frontal lobe, the temporal lobe and the cingulate gyrus as well as the cerebellum were activated in varying degrees and other brain regions were not activated by electroacupuncture at Neiguan (PC 6) in the AD group.
  
  
  CONCLUSIONS
  Acupuncture at Neiguan (PC 6) can activate functions of different brain regions in the healthy group and the AD group, indicating that acupuncture at Neiguan (PC 6) has different effects on functional magnetic resonance imaging in different functional states.
authors.affiliation: Xuanwu Hospital of Capital Medical University, Beijing 100053, China. doc_fuping@sina.com
authors.forename: Ping
authors.initials: P
authors.lastname: Fu
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Jia
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhu
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Huang
mesh_terms: D026881:Acupuncture; D015669:Acupuncture Points; D015670:Acupuncture Therapy; D001921:Brain; D006801:Humans; D008279:Magnetic Resonance Imaging