Assessment of ancestry probabilities in the presence of genotyping errors.
This paper extends an approach for estimating the ancestry probability, the probability that an inbred line is an ancestor of a given hybrid, to account for genotyping errors. The effect of such errors on ancestry probability estimates is evaluated through simulation. The simulation study shows that if misclassification is ignored, then ancestry probabilities may be slightly overestimated. The sensitivity of ancestry probability calculations to the assumed genotyping error rate is also assessed.
Zhang
Hongmei
H
Department of Mathematics and Statistics, The University of West Florida, Pensacola, FL 32514, USA. hzhang@uwf.edu
Stern
Hal
H
D000483:Alleles; D001499:Bayes Theorem; D002678:Chimera / Q000235:genetics; D003198:Computer Simulation; D008040:Genetic Linkage; D005819:Genetic Markers; D005838:Genotype; D016013:Likelihood Functions; D008433:Mathematics; D018895:Microsatellite Repeats; D008957:Models, Genetic; D011336:Probability
D005819:Genetic Markers