title: Heidelberg retina tomograph II findings of Acanthamoeba keratitis.
abstract: OBJECTIVE
  Heidelberg retina tomograph II (HRTII) examination was performed with cornea module in one patient with Acanthamoeba keratitis (AK) to provide images detailing characteristic findings of the disease.
  
  
  METHODS
  A 34-year-old woman presented with clinical signs and symptoms of AK. HRTII with cornea module was performed and the patient underwent laboratory investigations.
  
  
  RESULTS
  HRTII examination with cornea module revealed numerous 20-26-micro m diameter high-contrast round particles within the corneal epithelium and anterior stroma, resembling Acanthamoeba cysts. Stellate cells as well as ovoid irregular objects, possibly inflammatory cells, trophozoites, altered cysts, or activated keratocytes, were also present in the area of stromal infiltrates. Laboratory investigations confirmed the diagnosis of AK.
  
  
  CONCLUSIONS
  HRTII cornea module can be helpful in the diagnosis of AK by identifying acanthamoeba cyst-like structures in the cornea. This technique also has potential uses in monitoring the efficiency of anti-infective treatment.
authors.affiliation: Quinze-Vingts National Center of Ophthalmology, Universities Paris 6 and Paris 5, Paris, France. bourcier.flo@wanadoo.fr
authors.forename: Tristan
authors.initials: T
authors.lastname: Bourcier
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Dupas
authors.forename: Vincent
authors.initials: V
authors.lastname: Borderie
authors.forename: Christine
authors.initials: C
authors.lastname: Chaumeil
authors.forename: Pierre
authors.initials: P
authors.lastname: Larricart
authors.forename: Christophe
authors.initials: C
authors.lastname: Baudouin
authors.forename: Laurent
authors.initials: L
authors.lastname: Laroche
mesh_terms: D000048:Acanthamoeba / Q000235:genetics / Q000302:isolation & purification; D015823:Acanthamoeba Keratitis / Q000175:diagnosis* / Q000469:parasitology; D000328:Adult; D000818:Animals; D016054:DNA, Protozoan / Q000032:analysis; D003937:Diagnosis, Differential; D019573:Epithelium, Corneal / Q000469:parasitology / Q000473:pathology*; D005260:Female; D006801:Humans; D007834:Lasers; D009887:Ophthalmoscopy / Q000379:methods; D016133:Polymerase Chain Reaction; D012160:Retina; D014054:Tomography
chemical_list: D016054:DNA, Protozoan