[Effects of pricking blood therapy on ACTH contents in the hypothalamus-pituitary-adrenal axis in the rat of experimental allergic rhinitis].
OBJECTIVE
To explore the mechanism of pricking blood therapy (PBT) for allergic rhinitis (AR).


METHODS
The model rat of experimental allergic rhinitis (EAR) was established by administration of ovoglohulin and they were divided into five groups randomly: a model group, a PBT group, a TCM point application group, a beclomethasone dipropionate (BDP) treatment group, and a health control group. Adrenocorticotrophic hormone (ACTH) contents in hypothalamus, pituitary gland, adrenal gland and plasma were determined by radioimmunoassay before and after treatment.


RESULTS
The ACTH levels in the hypothalamus, pituitary gland, adrenal gland and plasma in the rat of EAR were lower than those in the health control group (P < 0.01). After treatment of pricking blood ther, ACTH levels in the above tissues increased significantly (P < 0.01), with very significant differences (P < 0.01) as compared with the model group, similar to those in the BDP group (P > 0.05).


CONCLUSIONS
Pricking blood therapy has a regulatory action on ACTH in HPA axis of rats with experimental allergic rhinitis.
Chen
Yong-hong
YH
Zhuang Medicine Hospital of Guangxi, Nanning 530001, China.
Lü
Lin
L
Chen
Hong
H
Dong
Ye
Y
Wei
Jin-yu
JY
Li
Yan
Y
Wei
Tao
T
D000324:Adrenocorticotropic Hormone; D000818:Animals; D007030:Hypothalamo-Hypophyseal System; D007031:Hypothalamus; D010913:Pituitary-Adrenal System; D051381:Rats; D065631:Rhinitis, Allergic
D000324:Adrenocorticotropic Hormone