[Early diagnosis of spondyloarthritis with special attention to the axial forms].
The axial spondyloarthritis (SpA) is the most important disease out of the whole group of SpA. If a sacroiliits is clearly detectable by x-rays a diagnosis of ankylosing spondylitis can be made. However, there is still a delay of 5-10 years from the first symptoms until a final diagnosis is made. An important reason for this is the fact that radiological changes are often only detectable after several years of disease, despite the presence of inflammation as detected by MRI and the presence of clinical manifestations such as pain and stiffness. An early diagnosis becomes more and more important because effective therapies have become available which are probably even more effective if given early. New strategies how to make an early diagnosis and how primary care physicians can screen for these patients are discussed.
Rudwaleit
M
M
Rheumatologie, Medizinische Klinik I, Charité, Universitätsmedizin Berlin Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany. martin.rudwaleit@charite.de
Sieper
J
J
D001268:Atlanto-Axial Joint / Q000473:pathology*; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011379:Prognosis; D025241:Spondylarthritis / Q000145:classification* / Q000175:diagnosis* / Q000628:therapy; D013997:Time Factors