Heteropoly acids as solid green Brønsted acids for a one-pot synthesis of beta-acetamido ketones by Dakin-West reaction.
An efficient improved procedure for the synthesis of beta-acetamido ketones has been developed by a heteropoly acid (HPA) catalyzed three-component coupling protocol. The present methodology offers several advantages such as excellent yields, simple procedure, short reaction times, and mild conditions.
Rafiee
Ezzat
E
Department of Chemistry, Faculty of Science, Razi University, Kermanshah 67149, Iran. e.rafiei@razi.ac.ir
Tork
Fariba
F
Joshaghani
M
M
D000081:Acetamides / Q000737:chemistry*; D000143:Acids / Q000737:chemistry*; D002384:Catalysis; D003116:Color; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D013696:Temperature
D000081:Acetamides; D000143:Acids; D007659:Ketones