Phosphoric acid-promoted synthesis of 4-acylpyrrole-2-carboxylic esters and dipyrryl ketones from mixed anhydrides.
[reaction: see text] An efficient synthesis of 4-acylpyrrole-2-carboxylic esters utilizing a phosphoric acid-catalyzed mixed anhydride system is described. The new route also enables the preparation of dipyrryl ketones and N-confused dipyrryl ketones.
Beshara
Cory S
CS
Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J3.
Thompson
Alison
A