title: Hormone replacement therapy and longitudinal cognitive performance in postmenopausal women.
abstract: OBJECTIVE
  The authors examined the impact of hormone replacement therapy (HRT) on longitudinal cognitive performance (controlling for mood state) in 69 community-dwelling, postmenopausal women.
  
  
  METHODS
  The authors conducted a 5-year follow-up of cognitive performance in 37 postmenopausal HRT users and 32 non-users. The groups did not differ with respect to age, years of education, or inter-test interval.
  
  
  RESULTS
  No main effect of HRT was observed on any of the cognitive measures, and depressive symptomatology did not affect the relationship between HRT and cognition.
  
  
  CONCLUSIONS
  Overall, our findings do not suggest that HRT affects longitudinal cognitive performance in postmenopausal, community-dwelling older women.
authors.affiliation: Dept. of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305-5550, USA. roh@leland.stanford.edu
authors.forename: Ruth
authors.initials: R
authors.lastname: O'Hara
authors.forename: Carmen M
authors.initials: CM
authors.lastname: Schröder
authors.forename: Cinnamon
authors.initials: C
authors.lastname: Bloss
authors.forename: Amber M
authors.initials: AM
authors.lastname: Bailey
authors.forename: Aviva M
authors.initials: AM
authors.lastname: Alyeshmerni
authors.forename: Martin S
authors.initials: MS
authors.lastname: Mumenthaler
authors.forename: Leah F
authors.initials: LF
authors.lastname: Friedman
authors.forename: Jerome A
authors.initials: JA
authors.lastname: Yesavage
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000187:drug effects*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D017698:Postmenopause / Q000502:physiology*; D011795:Surveys and Questionnaires