title: [A case report of recurrence of liver metastases from colorectal cancer, which seemed to have vanished for a time by intra-aortic chemotherapy].
abstract: A 66-year-old man underwent lower anterior resection for rectum cancer with multiple liver metastases. The diagnosis was Stage IV well-differentiated tubular adeno carcinoma. n1H3M(-). As adjuvant chemotherapy, we chose intra-arterial infusion of 5-FU 1,500 mg/body/week from July 2002 to February 2003. The metastatic focuses have become smaller and smaller until they seemed to be scars. In July 2003, there appeared to be a liver metastasis again, which emerged at the same place of the first metastatic focus. We tried intra arterial infusion of DXR in addition to intra-venous infusion of CPT-11, but it seemed to have no effect. Finally, we performed a partial resection of the liver in March 2005. There were many metastatic legions that emerged, but we successfully carried through partial resections for all legions. The uniqueness of this case was the liver metastasis that had appeared at the same place of the first metastatic focus. As the strategy for liver metastasis of colon cancer, it is better to perform a surgical resection as soon as the focus becomes resectable.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Bokutoh Hospital.
authors.forename: Yukako
authors.initials: Y
authors.lastname: Shiba
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Umekita
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Noda
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Kitamura
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology* / Q000556:secondary; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D015179:Colorectal Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage*; D006498:Hepatectomy; D006801:Humans; D007261:Infusions, Intra-Arterial; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D009364:Neoplasm Recurrence, Local
chemical_list: D000964:Antimetabolites, Antineoplastic; D000077146:Irinotecan; D005472:Fluorouracil; D002166:Camptothecin