Community acquired pneumonia (CAP) caused by Cryptococcus neoformans in a healthy individual.
A 41-y-old male had been diagnosed as having community acquired pneumonia (CAP) with consolidations in the chest radiograph, fever and cough. Since clarithromycin and ss-lactam agents were not effective, bronchoscopic examination was performed. Indian ink staining of bronchial wash smears revealed yeast-like cells with a thick capsule, and Cryptococcus neoformans was isolated several d later. Serum glucuronoxylomannan antigen was > or = x 1024. The patient was treated with itraconazole for 16 weeks.
Nakamura
Shigeki
S
Second Department of Internal Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
Miyazaki
Yoshitsugu
Y
Higashiyama
Yasuhito
Y
Yanagihara
Katsunori
K
Ohno
Hideaki
H
Hirakata
Yoichi
Y
Shikuwa
Masahiro
M
Mizuta
Yohei
Y
Tashiro
Takayoshi
T
Kohno
Shigeru
S
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003453:Cryptococcosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D011014:Pneumonia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
D000935:Antifungal Agents; D017964:Itraconazole