Enamel matrix proteins associated with GTR and bioactive glass in the treatment of class III furcation in dogs.
This study investigated, both histologically and histometrically, the efficacy of enamel matrix derived proteins (EMD) associated with bioactive glass (BG) and an absorbable membrane in the treatment of class III furcation defects in mongrel dogs. After surgical defect creation and chronification, the lesions were randomly divided into three groups according to the treatment employed: Test Group 1--EMD + BG + membrane, Test Group 2--EMD + membrane and Control Group--BG + membrane. After a 90-day healing period, the dogs were sacrificed. The descriptive analysis and the histometric data showed similar results for the experimental groups in all studied parameters (MANOVA, p > 0.05). The association of Emdogain with bioglass and GTR, or with GTR only, showed similar results when compared with the ones obtained with bioglass associated with membrane in the treatment of class III furcation defects in dogs. The three modalities of treatment showed partial filling of the furcations, with bone and cementum regeneration limited to the apical portion of the defects.
Fernandes
José Marcos Alves
JM
Department of Diagnosis and Surgery, School of Dentistry of Araraquara, São Paulo State University.
Rego
Rodrigo Otávio Citó César
RO
Spolidorio
Luis Carlos
LC
Marcantonio
Rosemary Adriana Chiérici
RA
Marcantonio Júnior
Elcio
E
Cirelli
Joni Augusto
JA
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects / Q000502:physiology; D003739:Dental Cementum / Q000187:drug effects / Q000502:physiology; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004285:Dogs; D017823:Furcation Defects / Q000473:pathology / Q000628:therapy*; D005898:Glass; D016557:Guided Tissue Regeneration, Periodontal
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins