title: Spinal hamartoma associated with spinal dysraphism.
abstract: OBJECTIVE
  The aims of the study were (1) to review the pathological findings of spinal lipomatous masses associated with congenital spinal dysraphism and (2) to discuss the pathological diagnosis.
  
  
  METHODS
  The pathological records of 47 patients at our institution were reviewed, and three illustrative cases were presented.
  
  
  CONCLUSIONS
  Spinal tumorous lesions associated with spinal dysraphism have been traditionally described as lipoma since they are composed mostly of fatty tissue. However, they are different from lipomas arising in other part of the body in that they often contain various tissues of ecto- and mesodermal origin. In our study, we detected such heterotopic components in 24 out of 47 cases. Although they are also similar to teratoma, it is generally accepted that they are malformative lesions which lack neoplastic potential. We therefore should diagnose them as hamartoma rather than lipoma or teratoma.
authors.affiliation: Department of Pathology, Miyagi Children's Hospital, 4-3-17 Ochiai, Aoba-ku, Sendai 989-3126, Japan. jtakeyama@miyagi-children.or.jp
authors.forename: Junji
authors.initials: J
authors.lastname: Takeyama
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hayashi
authors.forename: Mioko
authors.initials: M
authors.lastname: Saito
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Shimanuki
authors.forename: Mika
authors.initials: M
authors.lastname: Watanabe
authors.forename: Hironobu
authors.initials: H
authors.lastname: Sasano
authors.forename: Reizo
authors.initials: R
authors.lastname: Shirane
mesh_terms: D002648:Child; D003884:Dermoid Cyst / Q000151:congenital / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D006222:Hamartoma / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D009436:Neural Tube Defects / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012447:Sacrum / Q000473:pathology / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000151:congenital / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D016135:Spinal Dysraphism / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013125:Spinal Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013724:Teratoma / Q000151:congenital / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed