title: [Etiology of severe hospital infections in intensive care units and antibiotic resistance of pathogens].
abstract: The leading pathogens of severe infections in intensive care units were the following: respiratory tract infections--bacteria of the famility of Enterobacteriaceae (33.8%), Pseudomonas spp. (24.9%), Acinetobacter spp. (18.1%), Staphylococcus aureus (16.0%), blood flow infections--coagulase negative staphylococci (33.6%), S. aureus (26.1%), Enterobacteriaceae (17.6%), wound infections--Enterobacteriaceae (35.7%), coagulase negative staphyloccocci (17.8%), Pseudomonas spp. (14.3%). As for various species of Enterobacteriaceae, susceptibility was preserved in 91-100% of the isolates to meropenem, in 72-100% to cefoperazone/sulbactam, in 51-65% to cefepime, in 72-86% to amikacin, and in less than 50% to cephalosporins and fluoroquinolones. As for P.aeruginosa, 28% of the isolates was resistant to all the antibacterials, except polymyxin. The highest susceptibility to cefoperazone/sulbactam and meropenem was revealed in the isolates of Acinetobacter baumannii. Oxacillin resistance was detected in 64.9% of the S.aureus isolates. The oxacillin resistance as a rule was associated with resistance to macrolides, aminoglycosides and fluoroquinolones. As for coagulase negative staphylococci, oxacillin resistance was stated in 75.6% of the isolates. All the isolates of the Staphylococcus spp. preserved their susceptibility to vancomycin and linezolid.
authors.forename: S V
authors.initials: SV
authors.lastname: Sidorenko
authors.forename: S P
authors.initials: SP
authors.lastname: Rezvan
authors.forename: L V
authors.initials: LV
authors.lastname: Eremina
authors.forename: S V
authors.initials: SV
authors.lastname: Polikarpova
authors.forename: V I
authors.initials: VI
authors.lastname: Karabak
authors.forename: E D
authors.initials: ED
authors.lastname: Men'shikova
authors.forename: V I
authors.initials: VI
authors.lastname: Tishkov
authors.forename: E A
authors.initials: EA
authors.lastname: Cherkashin
authors.forename: V B
authors.initials: VB
authors.lastname: Beloborodov
mesh_terms: D003428:Cross Infection / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests