title: [Segmental mandibular reconstruction by elasticity distraction osteogenesis associated with guided bone regeneration].
abstract: OBJECTIVE
  To accelerate distraction osteogenesis by utilizing guided bone regeneration technique, and to improve the automatic process of canine segmental mandibular reconstruction by elasticity distraction osteogenesis using shape memory metal alloy distractor.
  
  
  METHODS
  Adult hybrid canines were used. Osteotomy was performed to remove a bone segment of 2.5-4.0 cm in one side of the mandible. Mandibular fixation devices and shape memory metal alloy distractor were secured according to the principles of bi-focal distraction technique. A piece of ePTFE membrane was sutured to cover the buccal side of bone defect and osteotomy gap of transport disc, where the periosteum was peeled for exposing mandible in operation. Then the incisions were totally closed. The canines were sacrificed 3 months later to harvest the mandibles for morphological observation and measurement of bone density and intensity.
  
  
  RESULTS
  The shape memory metal alloy distractor performed distraction osteogenesis automatically and reconstructed the mandibles with bone defect. A regenerated bone segment of 1.5-2.0 cm was formed in the compression region between transport disc and contralateral mandibular end. The new bone in both of distraction and compression regions had similar height and thickness with normal mandible. Moreover the new bone density and intensity were rather satisfied.
  
  
  CONCLUSIONS
  Membrane guided bone regeneration can avoid bone synthesis commonly caused by cicatrization of soft tissue in the bone defect, and accelerate ossification and maturation of new generated bone.
authors.affiliation: Department of Oral and Maxillofacial Surgery, College of Stomatology, The Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Hong-zhi
authors.initials: HZ
authors.lastname: Zhou
authors.forename: Min
authors.initials: M
authors.lastname: Hu
authors.forename: Hong-chen
authors.initials: HC
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Yao
authors.forename: Liang
authors.initials: L
authors.lastname: Ma
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D004285:Dogs; D048091:Guided Tissue Regeneration; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D009532:Nickel; D019857:Osteogenesis, Distraction / Q000295:instrumentation* / Q000379:methods; D014025:Titanium
chemical_list: C040654:titanium nickelide; D009532:Nickel; D014025:Titanium