title: [Clinical observation on medicine-separated moxibustion for treatment of primary dysmenorrhea and study on the mechanism].
abstract: OBJECTIVE
  To observe clinical therapeutic effect of medicine-separated moxibustion on primary dysmenorrhea and study on the mechanism.
  
  
  METHODS
  Ninety-six cases of primary dysmenorrhea were randomly divided into a treatment group and a control group, 48 cases in each group. They were treated respectively with medicine-separated moxibustion and Yueyueshu Perfusing Powder for 3 consecutive months.
  
  
  RESULTS
  The markedly effective and cured rate and the total effective rate were 87.5% and 100.0% in the treatment group, and 29.2% and 83.8% in the control group with significant differences between the two groups (P < 0.01 and P < 0.05). After treatment, blood prosglanding F2 content in menorrhea blood and oxytocin level in plasma during menstruation decreased significantly as compared with those before treatment (P < 0.01).
  
  
  CONCLUSIONS
  The medicine-separated moxibustion has a reliable therapeutic effect on primary dysmenorrhea and the therapeutic effect is exerted possibly by regulating abnormal prosglanding and oxytocin levels in the patient.
authors.affiliation: Nersing College of Taishan Medical College, Shandong 271000, China. wsmbest007@163.com
authors.forename: Song-Mei
authors.initials: SM
authors.lastname: Wang
authors.forename: Xing-Guo
authors.initials: XG
authors.lastname: Li
authors.forename: Li-Qun
authors.initials: LQ
authors.lastname: Zhang
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Xu
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
mesh_terms: D015669:Acupuncture Points; D004412:Dysmenorrhea / Q000628:therapy; D005260:Female; D006801:Humans; D009071:Moxibustion