title: Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer.
abstract: A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.
authors.affiliation: Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Marcel, lí Domingo s/n, Campus Sescelades, Tarragona, Spain.
authors.forename: Ester
authors.initials: E
authors.lastname: Caro
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Marcé
authors.forename: Peter A G
authors.initials: PA
authors.lastname: Cormack
authors.forename: David C
authors.initials: DC
authors.lastname: Sherrington
authors.forename: Francesc
authors.initials: F
authors.lastname: Borrull
mesh_terms: D000893:Anti-Inflammatory Agents / Q000032:analysis / Q000302:isolation & purification*; D045483:Rivers / Q000737:chemistry*; D014867:Water; D014876:Water Pollution
chemical_list: D000893:Anti-Inflammatory Agents; D014867:Water