title: Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center.
abstract: Aspergillus isolates (n = 103) collected from cancer patients were screened to determine the taxonomic distribution and quantity of gliotoxin production. Gliotoxin was detected in 93% of Aspergillus fumigatus, 75% of A. niger, 25% of A. terreus, and 4% of A. flavus cultures. Gliotoxin concentrations were highest in cultures of A. fumigatus.
authors.affiliation: University of Houston College of Pharmacy, Texas Medical Center Campus, 1441 Moursund St. #423, Houston, TX 77030, USA. rlewis@uh.edu
authors.forename: Russell E
authors.initials: RE
authors.lastname: Lewis
authors.forename: Nathan P
authors.initials: NP
authors.lastname: Wiederhold
authors.forename: Michail S
authors.initials: MS
authors.lastname: Lionakis
authors.forename: Randall A
authors.initials: RA
authors.lastname: Prince
authors.forename: Dimitrios P
authors.initials: DP
authors.lastname: Kontoyiannis
mesh_terms: D001228:Aspergillosis / Q000453:epidemiology* / Q000382:microbiology*; D001230:Aspergillus / Q000145:classification* / Q000254:growth & development / Q000302:isolation & purification*; D003470:Culture Media; D005912:Gliotoxin / Q000096:biosynthesis*; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D013045:Species Specificity
chemical_list: D003470:Culture Media; D005912:Gliotoxin