A simple different method to use proximal isovelocity surface area (PISA) for measuring mitral valve area.
BACKGROUND
Angle-correction is an important limiting factor for using proximal isovelocity surface area (PISA) method in measuring mitral valve area (MVA). In this study, we derived a novel formula, which simplifies the angle-correction, and tested its use in patients with mitral stenosis (MS).


METHODS
The study included 30 MS patients without concomitant aortic or mitral regurgitation. We used mathematical equations and established a relation between the angle and its corresponding border, 'a', by using linear regression analysis. It was found that MVA is equal to [(1.11*a2 + 0.95)* r2 (Val/Vmax)]. We compared this formula with plain angle-corrected and solid angle-corrected PISA methods, planimetry (reference method) and pressure-half time method by linear regression analysis.


RESULTS
All methods were in significant relation with the reference method, two-dimensional planimetry. We found that there is a good relation between our method and planimetry (r = 0.79, p < 0.001), pressure half-time method (r = 0.85, p < 0.001), angle-corrected PISA method (r = 0.99, p < 0.001), and solid angle-corrected PISA method (r = 0.88, p < 0.001). The time duration of the new method was shorter (p < 0.001).


CONCLUSIONS
Our method is an easy way for applying angle-corrected PISA method to mitral valve area measurement in patients with mitral stenosis. Absence of the need for estimating the angle is the major advantage.
Uzun
Mehmet
M
Department of Cardiology, Gulhane Military Medical Academy, Etlik, Ankara, Turkey. muzun1@yahoo.com
Baysan
Oben
O
Erinc
Kursad
K
Ozkan
Mustafa
M
Sag
Cemal
C
Genc
Celal
C
Karaeren
Hayrettin
H
Yokusoglu
Mehmet
M
Isik
Ersoy
E
D000328:Adult; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000473:pathology*; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000473:pathology*; D015588:Observer Variation; D011446:Prospective Studies; D015203:Reproducibility of Results