title: Microtubule flux: what is it good for?
abstract: During mitosis in a eukaryotic cell, microtubule subunits continuously move towards spindle poles. A new study has revealed that inhibiting this microtubule flux in mammalian cells has no major effects on chromosome movements; it does, however, increase the probability of erroneous chromosome segregation.
authors.affiliation: Division of Molecular Medicine,Wadsworth Center, New York State Department of Health, Albany, New York 12201-0509, USA.
authors.forename: Alexey
authors.initials: A
authors.lastname: Khodjakov
authors.forename: Tarun
authors.initials: T
authors.lastname: Kapoor
mesh_terms: D020090:Chromosome Segregation / Q000502:physiology*; D016547:Kinesins / Q000378:metabolism; D018386:Kinetochores / Q000502:physiology; D008870:Microtubules / Q000502:physiology*; D008938:Mitosis / Q000502:physiology*; D008954:Models, Biological; D008941:Spindle Apparatus / Q000502:physiology*; D014404:Tubulin / Q000378:metabolism
chemical_list: D014404:Tubulin; D016547:Kinesins