Intravascular pressure measurements in feeding pedicles of brain arteriovenous malformations.
Pressure measurements in arterial feeders of arteriovenous malformations (AVMs) can be easily acquired during endovascular treatment procedures. In this study, mean arterial pressure values in arterial feeders (Pfed) of brain AVMs were determined using a pressure measuring system connected to a standard microcatheter. A total of 148 measurements were performed in 139 patients. Mean systemic arterial pressure values were subtracted for correction. The levels of correlation between the pressure values and various clinical parameters (i.e., AVM location, size, previous hemorrhage) and pathoanatomical features of the AVM (e.g., nidus structure, number of draining veins) were determined. Pfed values were 54.5 mmHg on average. Pfed was lower in more distally located AVMs, in larger lesions and in AVMs with multiple drainage veins. Pressure values were significantly higher in patients with previous hemorrhage and in smaller AVMs. Our results support the importance of hemodynamic parameters in determining the presentation of AVMs. More extensive studies using this simple technique may further elucidate these mechanisms and may result in improved criteria for patient selection and reduction of complications.
Henkes
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H
Klinik füer Radiologie und Neuroradiologie, Alfried Krupp Krankenhaus, Essen, Germany. HHHenkes@aol.com
Gotwald
T F
TF
Brew
S
S
Miloslavski
E
E
Kämmerer
F
F
Kühne
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D017130:Angioplasty; D001794:Blood Pressure / Q000502:physiology*; D002531:Cerebellum / Q000098:blood supply*; D002536:Cerebral Arteries / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D002831:Choroid Plexus / Q000098:blood supply*; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged