GOAT: An R Tool for Analysing Gene Ontologytrade mark Term Enrichment.
Understanding the composition of gene lists that result from high-throughput experiments requires elaborate processing of gene annotation lists. In this article we present GOAT (Gene Ontology Analysis Tool), a tool based on the statistical software 'R' for analysing Gene Ontologytrade mark (GO) term enrichment in gene lists. Given a gene list, GOAT calculates the enrichment and statistical significance of every GO term and generates graphical presentations of significantly enriched terms. GOAT works for any organism with a genome-scale GO annotation and allows easy updates of ontologies and annotations.


BACKGROUND
GOAT is freely available from http://dictygenome.org/software/GOAT/ CONTACT: Gad Shaulsky (gadi@bcm.tmc.edu).
Xu
Qikai
Q
Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USADepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
Shaulsky
Gad
G