[Surfactants in dosage forms and biological systems. Part II].
The 2nd parts of publications are summarized the modern drug delivery systems contained surface active agents and the role of surfactants in the formation and stability of drug delivery systems. This paper reviews the structure and stability of multiple emulsions, and the different associates forming from surfactants. The solubilization is characterized and some mathematic functions between surface tension of surfactants and their solubilization capacity are introduced. Surfactants represent as important components of coherent emulsions, different vesicles and liposomes. The tensids have an important biopharmaceutical role. They can influenced the bioavailability by increase of thermodynamic activity of active substance and by change of permeability of cellular membranes.
Eros
István
I
Szegedi Tudományegyetem, Gyógyszertechnológiai Intézet, Szeged, Eötvös u. 6. - 6720.
D004304:Dosage Forms; D004655:Emulsions; D008081:Liposomes; D004364:Pharmaceutical Preparations; D012995:Solubility; D013501:Surface-Active Agents / Q000737:chemistry*
D004304:Dosage Forms; D004655:Emulsions; D008081:Liposomes; D004364:Pharmaceutical Preparations; D013501:Surface-Active Agents