title: Role of glucocorticoids in dopamine-related neuropsychiatric disorders.
abstract: 'Psychoneuroendocrinology' is now quickly emerging as a hot interdisciplinary research field that addresses the interplay between neuronal and endocrine signaling in psychiatric diseases. Both glucocorticoid hormones and dopamine have an important role in maintaining normal brain functions. In this review, molecular and mechanistic aspects of glucocorticoid effects on brain function and behavior will be discussed with specific reference to dopamine signaling.
authors.affiliation: Laboratory for Eukaryotic Gene Expression and Signal Transduction, LEGEST, Department of Molecular Biology, Ghent University-UGent, K.L. Ledeganckstraat 35, 9000 Gent, Belgium.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Van Craenenbroeck
authors.forename: Karolien
authors.initials: K
authors.lastname: De Bosscher
authors.forename: Wim
authors.initials: W
authors.lastname: Vanden Berghe
authors.forename: Peter
authors.initials: P
authors.lastname: Vanhoenacker
authors.forename: Guy
authors.initials: G
authors.lastname: Haegeman
mesh_terms: D000818:Animals; D016739:Behavior, Addictive / Q000503:physiopathology; D003865:Major Depressive Disorder / Q000503:physiopathology; D004298:Dopamine / Q000235:genetics / Q000502:physiology*; D044127:Epigenesis, Genetic; D005786:Gene Expression Regulation / Q000502:physiology; D005938:Glucocorticoids / Q000235:genetics / Q000502:physiology*; D006801:Humans; D001523:Mental Disorders / Q000503:physiopathology*; D018377:Neurotransmitter Agents / Q000502:physiology; D010300:Parkinson Disease / Q000503:physiopathology; D020239:Receptor Cross-Talk / Q000502:physiology; D011954:Receptors, Dopamine / Q000235:genetics / Q000502:physiology; D011965:Receptors, Glucocorticoid / Q000235:genetics / Q000502:physiology; D012559:Schizophrenia / Q000503:physiopathology; D015398:Signal Transduction
chemical_list: D005938:Glucocorticoids; D018377:Neurotransmitter Agents; D011954:Receptors, Dopamine; D011965:Receptors, Glucocorticoid; D004298:Dopamine