Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry.
In this paper a rapid optimized method for routine analysis of carbendazim residues in fruit juices is reported. The procedure is based on matrix solid-phase dispersion (MSPD) with diatomaceous earth and analysis of the extract by liquid chromatography-tandem mass spectrometry, with electrospray ionization (LC-ESI-MS/MS). In the method optimization, finding of the optimal pH for the extraction of carbendazim from juice was particularly critical. Significant matrix effects were observed, but could be eliminated using matrix-matched standards. High recoveries (82-102%), good repeatability (RSD<or=12%) and low limits of detection (0.03 ng ml-1) and quantification (0.1 ng ml-1) were achieved with this method.
Grujic
Svetlana
S
Faculty of Technology and Metallurgy - Analytical Chemistry, Belgrade, Serbia and Montenegro. cekili@tmf.bg.ac.yu
Radisic
Marina
M
Vasiljevic
Tatjana
T
Lausevic
Mila
M
D001562:Benzimidazoles / Q000032:analysis*; D001628:Beverages / Q000032:analysis*; D002219:Carbamates / Q000032:analysis*; D002853:Chromatography, Liquid / Q000379:methods; D005504:Food Analysis / Q000379:methods; D005506:Food Contamination / Q000032:analysis*; D005638:Fruit / Q000737:chemistry*; D005659:Fungicides, Industrial / Q000032:analysis; D006801:Humans; D010573:Pesticide Residues / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
D001562:Benzimidazoles; D002219:Carbamates; D005659:Fungicides, Industrial; D010573:Pesticide Residues; C006698:carbendazim