Atypical cytogenetic presentation of t(11;14) in mantle cell lymphoma.
Eighteen cases of mantle cell lymphomas (MCL) with an atypical t(11;14) were studied using fluorescence in situ hybridization experiments (FISH). The atypical presentation was confirmed and unsuspected duplicated cases were identified in six patients. These data underline that FISH analysis must be be systematically performed in cases with an aberrant presentation to prevent a misdiagnosis.
Gazzo
Sophie
S
Felman
Pascale
P
Berger
Françoise
F
Salles
Gilles
G
Magaud
Jean-Pierre
JP
Callet-Bauchu
Evelyne
E
D000782:Aneuploidy; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics* / Q000648:ultrastructure; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics* / Q000648:ultrastructure; D020440:Gene Duplication; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D020522:Lymphoma, Mantle-Cell / Q000235:genetics*; D014178:Translocation, Genetic