Imaging tumor angiogenesis: functional assessment using MDCT or MRI?
Functional imaging using multidetector row computed tomography and dynamic contrast-enhanced magnetic resonance imaging are increasingly advocated for assessment of tumor vascularity because these techniques provide excellent anatomic imaging and reliable quantitative perfusion data and are easily incorporated into routine examinations. However, differences in acquisition techniques, mathematical analysis, measurement parameters, and propensity to artifacts influence the choice of imaging modality, which is explored in this review.
Goh
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Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, United Kingdom. vicky.goh@paulstrickland-scannercentre.org.uk
Padhani
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AR
D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009389:Neovascularization, Pathologic / Q000175:diagnosis*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003287:Contrast Media