Community-associated methicillin-resistant Staphylococcus aureus, Minnesota, 2000-2003.
We compared characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) and CA-MRSA invasive disease identified in Minnesota from 2000 through 2003. A total of 586 patients with SSTIs and 65 patients with invasive disease were identified. Patients with invasive disease were more likely to be smokers (p = 0.03), and report a history of immunosuppressive therapy (p = 0.03), emphysema (p = 0.011), or injection drug use (p = 0.020) than were SSTI patients. Invasive disease isolates were less likely to be susceptible to ciprofloxacin (p = 0.002) and clindamycin (p = 0.001) and more likely to have healthcare-associated pulsed-field gel electrophoresis subtypes than SSTI isolates (p<0.001). Patients with invasive disease may have had healthcare exposures that put them at risk of acquiring healthcare-associated MRSA and which were not exclusion criteria in the CA-MRSA case definition. Continued surveillance of MRSA is needed to better characterize CA-MRSA infections.
Buck
Jessica M
JM
Minnesota Department of Health, Minneapolis, Minnesota, USA.
Como-Sabetti
Kathryn
K
Harriman
Kathleen H
KH
Danila
Richard N
RN
Boxrud
David J
DJ
Glennen
Anita
A
Lynfield
Ruth
R
D000328:Adult; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008910:Minnesota / Q000453:epidemiology; D012307:Risk Factors; D018461:Soft Tissue Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology; D013207:Staphylococcal Skin Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification