[Evaluation of the endoprosthesis by metallic stent and tube stent for malignant biliary stenosis].
We evaluated the effect of biliary endoprotheses for 20 malignant stenosis patients by an expandable metallic stent and hydrophilic heparinized tube (H-PSD) connected to an implantable port (IP), which reduces bacterial adherence. Group A consisted of 6 patients of cholangiocarcinoma who underwent hepatic arterial infusion chemotherapy associated with radiotherapy. Groups B and C consisted of 8 and 6 patients of stage IVa and IVb pancreatic carcinoma, respectively, who underwent hepatic and splenic arterial infusion chemotherapy following transcatheter peripancreatic arterial embolization. The 50% patent time was 12 months, 6 months and 7 months in groups A, B and C and the 50% overall survival time was 16 months, 23 months and 13 months, respectively. There were two complications, 1 case of infection around the IP in which the IP was withdrawn, and 3 cases of cholangitis in which we had easy access to the bile duct via IP. This technique appears to offer significant benefit in selecting patients with this type of biliary obstruction.
Takahashi
Sho
S
Gastroenterology Center, Sapporo Medical University School of Medicine.
Homma
Hisato
H
Akiyama
Takehide
T
Mesawa
Shinichi
S
Koike
Kazuhiko
K
Kogawa
Katsuhisa
K
Hirata
Kenichiro
K
Niitsus
Yoshiro
Y
D000368:Aged; D000369:Aged, 80 and over; D018281:Cholangiocarcinoma / Q000150:complications*; D002779:Cholestasis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome