title: Management of severe hypotony with intravitreal injection of viscoelastic.
abstract: OBJECTIVE
  To investigate the effect of an intravitreal injection of sodium hyaluronate 1.4% and 2.3% in the treatment of hypotony.
  
  
  METHODS
  Interventional case series.
  
  
  METHODS
  Intravitreal injection of sodium hyaluronate 1.4% was performed to treat persistent hypotony in three eyes after the successful repair of retinal detachment and in one eye with uveitis. Injection of sodium hyaluronate 2.3% was performed in one eye after the successful repair of retinal detachment with removal of silicone oil.
  
  
  RESULTS
  At the last follow-up examination (2-16 months), intraocular pressure increased to at least 5 mm Hg (5-14 mm Hg) in all eyes that had been injected with sodium hyaluronate. Intraocular pressure increased to 38 mm Hg in the eye that had been injected with sodium hyaluronate 2.3% on postoperative day 1 and was 10 mm Hg at three months. Vision improved in all patients.
  
  
  CONCLUSIONS
  Intraocular injection of sodium hyaluronate 1.4 and 2.3% appears to be efficacious in reversing hypotony in some eyes. Functional and structural findings can also improve.
authors.affiliation: Department of Ophthalmology, Edward S. Harkness Eye Institute, New York Presbyterian Hospital, New York 10032, USA
authors.forename: Gian Marco
authors.initials: GM
authors.lastname: Tosi
authors.forename: William
authors.initials: W
authors.lastname: Schiff
authors.forename: Gaetano
authors.initials: G
authors.lastname: Barile
authors.forename: Norihiko
authors.initials: N
authors.lastname: Yoshida
authors.forename: Stanley
authors.initials: S
authors.lastname: Chang
mesh_terms: D000368:Aged; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects*; D008875:Middle Aged; D015814:Ocular Hypotension / Q000188:drug therapy*; D012163:Retinal Detachment / Q000601:surgery; D014065:Tonometry, Ocular; D015866:Uveitis, Posterior / Q000601:surgery; D014792:Visual Acuity; D014822:Vitreous Body
chemical_list: D006820:Hyaluronic Acid