title: A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus.
abstract: The antibacterial activity of Haplopappus uncinatus is attributed to a new clerodane diterpenoid, 18-acetoxy-cis-cleroda-3-en-15-oic acid (10 betaH, 16 xi 19 beta, 17beta, 20 alpha form) (1), isolated as a major component from the resinous exudates of its twigs and leaves, together with the inactive 3,5-dihydroxy-6,7,3',4'-tetramethoxyflavone, n-alkanes and a few sesquiterpenoids.
authors.affiliation: Facultad de Química y Biología, Universidad de Santiago, Casilla 40, Correo 33 Santiago, Chile. aurzuamoll44@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Urzúa
authors.forename: F
authors.initials: F
authors.lastname: Jara
authors.forename: E
authors.initials: E
authors.lastname: Tojo
authors.forename: M
authors.initials: M
authors.lastname: Wilkens
authors.forename: L
authors.initials: L
authors.lastname: Mendoza
authors.forename: M C
authors.initials: MC
authors.lastname: Rezende
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D031206:Haplopappus; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D004224:Diterpenes; D010936:Plant Extracts