title: Protection of the carbonyl group as 1,2,4-trioxane and its regeneration under basic conditions.
abstract: [chemical reaction: see text]. An experimental protocol demonstrating the protection of the carbonyl group as 1,2,4-trioxane, the stability of the protecting group under a variety of reaction conditions, and the regeneration of the carbonyl group with Triton B in THF at room temperature is presented. The method provides a useful alternative for the protection of carbonyl compounds having acid-sensitive moieties.
authors.affiliation: Division of Medicinal and Process Chemistry, Central Drug Research Institute, Lucknow 226001, India. chandancdri@yahoo.com
authors.forename: Chandan
authors.initials: C
authors.lastname: Singh
authors.forename: Heetika
authors.initials: H
authors.lastname: Malik