title: Paediatric fibro-osseous lesions of the nose and paranasal sinuses.
abstract: OBJECTIVE
  The term "fibro-osseous lesion" is a generic description for a group of lesions involving the paranasal sinuses and anterior skull base. We aim to improve understanding of the clinical and pathological presentation of fibro-osseous lesions in children.
  
  
  RESULTS
  We report two cases of aggressive "fibro-osseous" lesions arising from paranasal sinuses and anterior skull base in childhood that were successfully managed surgically. We compare our case reports with a review of the available literature and evaluate the management of these lesions.
  
  
  CONCLUSIONS
  The clinical behaviour and radiological features of fibro-osseous lesions is variable. Aggressive lesions require a radical surgical approach to ensure complete excision, in spite of an increase in associated morbidity. Incomplete excision of aggressive lesions may result in disease recurrence with severe morbidity or mortality. In contrast a slowly progressive lesion often does not warrant extensive surgical excision. Understanding the nature of fibro-osseous lesions facilitates appropriate clinical management.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Queens Medical Centre, Nottingham, UK.
authors.forename: D
authors.initials: D
authors.lastname: Mehta
authors.forename: N
authors.initials: N
authors.lastname: Clifton
authors.forename: L
authors.initials: L
authors.lastname: McClelland
authors.forename: N S
authors.initials: NS
authors.lastname: Jones
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D018214:Fibroma, Ossifying / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D005357:Fibrous Dysplasia of Bone / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome