title: Hyperkeratotic head and neck Malassezia dermatosis.
abstract: BACKGROUND
  Pityriasis versicolor (tinea versicolor) is a common skin disorder due to Malassezia usually affecting adolescents and young adults, more frequently in the tropics. Facial involvement, isolated or not, is not frequent in white adults.
  
  
  OBJECTIVE
  Here, we report a possible atypical hyperkeratotic form of dermatosis of the face, in two young immunocompetent Caucasian patients, particularly recalcitrant to therapy.
  
  
  RESULTS
  Skin scrapings grew yeasts belonging to the genus Malassezia, including both M. globosa and M. sympodialis. This unusual variant needs long-term therapy with systemic and topical imidazoles together with facial cleansing.
  
  
  CONCLUSIONS
  We propose the name hyperkeratotic head and neck Malassezia dermatosis for this distinctive clinical entity. This variant of pityriasis versicolor should be considered in the differential diagnosis of seborrheic dermatitis and dermatitis neglecta.
authors.affiliation: Department of Dermatology, Hôpital Saint-André, Bordeaux, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Boralevi
authors.forename: Josefina
authors.initials: J
authors.lastname: Marco-Bonnet
authors.forename: Sebastien
authors.initials: S
authors.lastname: Lepreux
authors.forename: Christel
authors.initials: C
authors.lastname: Buzenet
authors.forename: Bernard
authors.initials: B
authors.lastname: Couprie
authors.forename: Alain
authors.initials: A
authors.lastname: Taïeb
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006257:Head; D006801:Humans; D007642:Keratosis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D007654:Ketoconazole / Q000008:administration & dosage / Q000627:therapeutic use; D008290:Malassezia / Q000187:drug effects / Q000302:isolation & purification*; D008297:Male; D009333:Neck; D009626:Terminology as Topic; D014010:Tinea Versicolor / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D007654:Ketoconazole