title: [TPA increases cell proliferation of HEp-2 cell line in vitro].
abstract: OBJECTIVE
  To investigate the influence of TPA treatment on HEp-2 cell line in vitro.
  
  
  METHODS
  HEp-2 cell line cultured in vitro was treated by different concentration levels of TPA. MTT method was used to detect survival cell ratio of HEp-2.
  
  
  RESULTS
  Cell growth of HEp-2 after treatment of TPA manifested an peak. The highest peak which was 1.3 to 1.4 times of control cell presented on 10 microg/L concentration level. Cell proliferation ability dropped gradually following increase of TPA concentration.
  
  
  CONCLUSIONS
  TPA can increase cell proliferation of HEp-2 cell in vitro.
authors.affiliation: Cancer Center of Sun Yat-Sen University, Guangzhou 510060, China. drliuwei@163.com
authors.forename: Weiwei
authors.initials: W
authors.lastname: Liu
authors.forename: Zongyuan
authors.initials: Z
authors.lastname: Zeng
authors.forename: Xibin
authors.initials: X
authors.lastname: Xiao
mesh_terms: D002273:Carcinogens / Q000633:toxicity; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D013755:Tetradecanoylphorbol Acetate / Q000633:toxicity*
chemical_list: D002273:Carcinogens; D013755:Tetradecanoylphorbol Acetate