title: Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity.
abstract: Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Stachys bombycina (Lamiaceae) afforded two acylated flavonoids glycosides, chrysoeriol 7-O-[6-O-acetyl-beta-D-allopyranosyl]-(1 --> 2)-beta-D-glucopyranoside (1) and apigenin 7-O-beta-D-(6-p-coumaroyl)-glucopyranoside (2), the former being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques. The free radical scavenging activity of 1 and 2 compounds were assessed by DPPH assay, and the RC50 values were 1.25 x 10(-2) and 7.69 x 10(-4) mg/mL, respectively.
authors.affiliation: School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Delazar
authors.forename: S
authors.initials: S
authors.lastname: Celik
authors.forename: R S
authors.initials: RS
authors.lastname: Göktürk
authors.forename: O
authors.initials: O
authors.lastname: Unal
authors.forename: L
authors.initials: L
authors.lastname: Nahar
authors.forename: S D
authors.initials: SD
authors.lastname: Sarker
mesh_terms: D000215:Acylation; D047310:Apigenin / Q000737:chemistry*; D019540:Area Under Curve; D002851:Chromatography, High Pressure Liquid; D047309:Flavones; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D016166:Free Radical Scavengers; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D031366:Stachys / Q000737:chemistry*
chemical_list: D047309:Flavones; D005419:Flavonoids; D016166:Free Radical Scavengers; D006027:Glycosides; D010936:Plant Extracts; D047310:Apigenin; C007054:chrysoeriol