[Serum creatine kinase levels and the number of sarcolemmal dystrophin disruptions in human skeletal muscle fibers under conditions of weightlessness simulation].
9 male volunteers took part in the experiment. They were divided in two groups. 5 volunteers (control group) have been in "dry" immersion for 7 days. 4 volunteers (stimulated group) in addition to "dry" immersion were treated with artificial support stimulation. We investigated the number of muscle fibers with the disruptions of sarcolemmal dystrophin and serum creatine kinase levels. 7-day "dry" immersion did not change the mean number of muscle fibers with dystrophin disruptions, it led to significant decrease of serum creatine kinase levels and did not influence on the sensitivity of sarcolemma to injury. Artificial support stimulation did not influence on these parameters.
Gasnikova
N M
NM
Markin
A A
AA
Kozlovskaia
I B
IB
Larina
I M
IM
Shenkman
B S
BS
D000328:Adult; D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism*; D016189:Dystrophin / Q000378:metabolism*; D006801:Humans; D008297:Male; D018485:Muscle Fibers, Skeletal / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism; D012508:Sarcolemma / Q000473:pathology; D013997:Time Factors; D018474:Weightlessness Simulation
D016189:Dystrophin; D003402:Creatine Kinase