title: [Sagittal balance of the spine and degenerative spondylolisthesis].
abstract: OBJECTIVE
  Several reports have examined the pathophysiology of degenerative spondylolisthesis. Very little work has however been devoted to the influence of spinal balance in the sagittal plane in its pathogenesis. The purpose of this work was to present a descriptive analysis of pelvic and spinal sagittal balance in a cohort of seventy patients treated for degenerative spondylolisthesis and to compare findings with those established in a population of 250 volunteers. The goal was to deduct pathophysiological hypotheses and identify therapeutic implications.
  
  
  METHODS
  Seventy patients were included in this study. The following variables were noted: pelvic incidence and version, sacral slope, lumbar lordosis, thoracic kyphosis, T9 sagittal tilt and S1-S2 angle. These variables were measured on digitalized lateral views of the spine using a dedicated software (SpineView). Univariate analysis of the values obtained was performed to identify the variable distributions. Multivariate analysis was applied to study the relationships between these variables and to better define perturbations of spinal balance in the anteroposterior plane. The findings were compared with those obtained in a control population.
  
  
  RESULTS
  One of the essential characteristics of the cohort of patients with degenerative spondylolisthesis was the presence of an exaggerated pelvic incidence (62.6 degrees versus 54.7 degrees in the control population). The most significant determinants of T9 sagittal tilt (which reflects sagittal balance) were: pelvic version, pelvic incidence, lumbar lordosis, and L4-S1 local lordosis. One-third of our patients presented posterior tilt due to exaggerated thoracic kyphosis. The high pelvic incidence, via hyperlordosis and increased pelvic version, could be one of the factors favoring degenerative disease of the spinal unit.
  
  
  CONCLUSIONS
  This work enabled us to better describe sagittal balance in patients with degenerative spondylolisthesis and to propose hypotheses concerning the underlying mechanism of progressive degeneration. We emphasize the diversity of spinal balance in these patients and the different therapeutic implications.
authors.affiliation: Service de Chirurgie Orthopédique, Hôpital Beaujon, 100, boulevard du Général-Leclerc, 92110 Clichy.
authors.forename: E
authors.initials: E
authors.lastname: Morel
authors.forename: B
authors.initials: B
authors.lastname: Ilharreborde
authors.forename: T
authors.initials: T
authors.lastname: Lenoir
authors.forename: E
authors.initials: E
authors.lastname: Hoffmann
authors.forename: R
authors.initials: R
authors.lastname: Vialle
authors.forename: L
authors.initials: L
authors.lastname: Rillardon
authors.forename: P
authors.initials: P
authors.lastname: Guigui
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000503:physiopathology; D004856:Postural Balance; D012447:Sacrum; D013131:Spine / Q000503:physiopathology*; D013168:Spondylolisthesis / Q000503:physiopathology*