Vitamin B12 deficiency in infancy as a cause of developmental regression.
Vitamin B12 deficiency can cause serious developmental regression, hypotonia and cerebral atrophy in infants. We report a 6-month-old infant, with insidious developmental regression and brain atrophy showed by CT scan, secondarily to vitamin B12 deficiency. His mother was a strict vegetarian and the patient was exclusively breastfed. The clinical symptoms and the brain CT were normalized after vitamin B12 administration.
Casella
Erasmo Barbante
EB
Child Neurology Unit, Pediatric Department, University of São Paulo Medical School, São Paulo, Brazil. erasmobc@icr.hcnet.usp.br
Valente
Marcelo
M
de Navarro
Jessie Medeiros
JM
Kok
Fernando
F
D001284:Atrophy; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001942:Breast Feeding; D002658:Developmental Disabilities / Q000209:etiology*; D014676:Diet, Vegetarian / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D009123:Muscle Hypotonia / Q000209:etiology; D011859:Radiography; D014805:Vitamin B 12 / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000188:drug therapy
D014805:Vitamin B 12