Eremostachiin: a new furanolabdane diterpene glycoside from Eremostachys glabra.
The reversed-phase preparative HPLC analysis of the methanol extract of the rhizomes of Eremostachys glabra (Lamiaceae) led to the isolation of two furanolabdane diterpene glycosides, phlomisoside II, and beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl ester of phlomisoic acid (named eremostachiin), the latter being a novel natural product. The structure of the new compound has been elucidated unambiguously by HRMS and a series of 1D- and 2D-NMR spectroscopic techniques. The free radical scavenging activity of these compounds was assessed using the DPPH assay.
Delazar
Abbas
A
School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Modarresi
Masoud
M
Shoeb
Mohammad
M
Nahar
Lutfun
L
Reid
Raymond G
RG
Kumarasamy
Yashodharan
Y
Majinda
Runner R T
RR
Sarker
Satyajit D
SD
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D019686:Lamiaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D027343:Rhizome / Q000737:chemistry*
D004224:Diterpenes; D005960:Glucosides; C509360:eremostachiin