title: Aerobic oxidative cyclization under Pd(II) catalysis: a regioselective approach to heterocycles.
abstract: [chemical reaction: see text]. An efficient Yb(OTf)3-promoted palladium-catalyzed oxidative cyclization of gamma-heteroalkenyl beta-keto amides has been developed. Under simple aerobic condition, a variety of six-, seven-, and eight-membered-ring N- and O-heterocycles were obtained regioselectively in excellent yield.
authors.affiliation: Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.
authors.forename: Kai-Tai
authors.initials: KT
authors.lastname: Yip
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
authors.forename: On-Yi
authors.initials: OY
authors.lastname: Lee
authors.forename: Dan
authors.initials: D
authors.lastname: Yang