Neurocutaneous melanosis: an atypical presentation.
An eleven-year-old male child presented with multiple small melanocytic nevi in a generalized distribution and a giant congenital melanocytic nevus (GCMN) over the lumbosacral area since birth. He had had difficulty in walking since the age of two and a half years. Histopathological examination revealed intradermal melanocytic nevi. Serial Magnetic Resonance Imaging (MRI) scans showed brainstem atrophy with central nervous system abnormality suggestive of neuromelanosis. Clinically and histologically, the diagnosis was suggestive of neurocutaneous melanosis (NCM). The present case is reported due to its clinical presentation of quadriparesis, which has been rarely reported as a manifestation of neurocutaneous melanosis.
Khera
Siddharth
S
Department of Dermatology and Venereology, Vardhman Mahavir Medical College and Safdarjang Hospital, New Delhi, India.
Sarkar
Rashmi
R
Jain
Rakesh Kumar
RK
Saxena
Ashok Kumar
AK
D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008548:Melanosis / Q000150:complications / Q000473:pathology*; D020752:Neurocutaneous Syndromes / Q000150:complications / Q000473:pathology*; D009508:Nevus, Pigmented / Q000151:congenital / Q000473:pathology; D011782:Quadriplegia / Q000150:complications; D012878:Skin Neoplasms / Q000151:congenital / Q000473:pathology