title: [Relationship between serum resistin level and preeclampsia].
abstract: To investigate the alteration of serum resistin levels in normal pregnancy and preeclampsia.
  
  
  
  Blood samples were take from 28 normal non-pregnant women, 27 women in the 1st, 26 in the 2nd and 26 in the 3rd trimester of normal pregnancy and 25 women with preeclampsia. Serum resistin concentration was determined using ELISA method.
  
  
  
  Serum levels of resistin were not significantly different among non-pregnancy, the 1st and the 2nd trimester of pregnancy (P>0.05 for all). Serum resistin level was significantly elevated in the 3rd trimester of pregnancy as compared with non-pregnancy (P<0.01), the 1st (P<0.001) and the 2nd trimester of pregnancy (P<0.001). Serum resistin level was significantly lower in preeclampsia than in the 3rd trimester of normal pregnancy (P<0.001), but was comparable to that of non-pregnancy, the 1st and the 2nd trimester of pregnancy (P>0.05 for all).
  
  
  
  The decrease of serum resistin level in the preeclampsia may provide insight into the pathogenesis of the disease.
authors.affiliation: The Affiliated Obstetrics and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China. chendq@zju.edu.cn
authors.forename: Dan-qing
authors.initials: DQ
authors.lastname: Chen
authors.forename: Zheng
authors.initials: Z
authors.lastname: Shi
authors.forename: Min-yue
authors.initials: MY
authors.lastname: Dong
authors.forename: Qin
authors.initials: Q
authors.lastname: Fang
authors.forename: Jing
authors.initials: J
authors.lastname: He
authors.forename: Zheng-ping
authors.initials: ZP
authors.lastname: Wang
authors.forename: Xiao-fu
authors.initials: XF
authors.lastname: Yang
mesh_terms: D000328:Adult; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000097:blood; D052243:Resistin / Q000097:blood*
chemical_list: D052243:Resistin