title: Hemodynamic effects of osteopathic manipulative treatment immediately after coronary artery bypass graft surgery.
abstract: BACKGROUND
  Coronary artery bypass graft (CABG) surgery is a common procedure for patients with coronary artery disease. The physiologic effects of postoperative osteopathic manipulative treatment (OMT) following CABG have not been documented previously.
  
  
  OBJECTIVE
  To determine the effects of OMT on cardiac hemodynamics post-CABG surgery.
  
  
  METHODS
  Pilot prospective clinical study (N=29).
  
  
  METHODS
  Treatment subjects (n=10) undergoing CABG surgery were recruited for postoperative OMT. The primary assessment compared, pre-OMT versus post-OMT, measurements of thoracic impedance, mixed venous oxygen saturation (SvO2), and cardiac index. Records of control subjects (n=19) who underwent CABG surgery--but who did not receive OMT--were assessed for SvO2 and cardiac index at 1 hour and 2 hours postsurgery.
  
  
  METHODS
  Immediately following CABG surgery (< or = 2 h), OMT was provided to subjects to alleviate anatomic dysfunction of the rib cage caused by median sternotomy and to improve respiratory function. This adjunctive treatment occurred while subjects were completely anesthetized.
  
  
  RESULTS
  A post-OMT increase in thoracic impedance (P < or = .02) in OMT subjects demonstrated that central blood volume was reduced after OMT, suggesting an improved peripheral circulation. Mixed venous oxygen saturation also increased (P < or = .005) after OMT. These increases were accompanied by an improvement in cardiac index (P < or = .01). Comparisons of postoperative measurements in OMT subjects versus those in control subjects revealed statistically significant differences for SvO2 (P < or = .005) and cardiac index (P < or = .02) between the two groups.
  
  
  CONCLUSIONS
  The observed changes in cardiac function and perfusion indicated that OMT had a beneficial effect on the recovery of patients after CABG surgery. The authors conclude that OMT has immediate, beneficial hemodynamic effects after CABG surgery when administered while the patient is sedated and pharmacologically paralyzed.
authors.affiliation: Department of Surgery, Texas College of Osteopathic Medicine, University of North Texas Health Center, Fort Worth, TX 76107, USA.
authors.forename: Albert H
authors.initials: AH
authors.lastname: O-Yurvati
authors.forename: Michael S
authors.initials: MS
authors.lastname: Carnes
authors.forename: Michael B
authors.initials: MB
authors.lastname: Clearfield
authors.forename: Scott T
authors.initials: ST
authors.lastname: Stoll
authors.forename: Walter J
authors.initials: WJ
authors.lastname: McConathy
mesh_terms: D000368:Aged; D001810:Blood Volume; D002302:Cardiac Output; D001026:Coronary Artery Bypass; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D026301:Manipulation, Osteopathic; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010865:Pilot Projects; D011182:Postoperative Care; D011446:Prospective Studies
chemical_list: D010100:Oxygen