title: Detection of dopamine in the pharmacy with a carbon nanotube paste electrode using voltammetry.
abstract: A simply prepared DNA immobilized on a carbon nanotube paste electrode (CNTPE) was utilized to monitor dopamine ion concentration using the cyclic voltammetry (CV) and square-wave (SW) stripping voltammetry methods. The optimum analytical conditions were sought. The result obtained was a very low detection limit compared to other common voltammetry methods. The optimal parameters were found to be as follows: 3.5 pH, 0.48 V SW amplitude, 71 Hz frequency, 5 s accumulation time, 0.01 V increment potential, and -1.3 V (anodic-*-) and 1.2 V (cathodic-o-) accumulation potentials. Given these conditions, the linear working range was observed to be within 0.01-0.11 microg L(-1) (SW anodic and CV). The analytical detection limit was determined to be SW anodic and CV: 4.0 microg L(-1) (2.1 x 10(-11) mol L(-1)) dopamin, and the relative standard deviation at the dopamine concentration of SW anodic 0.05 microg L(-1) was 0.02% (n=15) at the optimum conditions.
authors.affiliation: Biosensor Research Institute in Seoul National University of Technology, 172, gongreung 2 dong Nowon gu, Seoul, South Korea, 139-743.
authors.forename: Suw Young
authors.initials: SY
authors.lastname: Ly
mesh_terms: D000042:Absorption; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004247:DNA / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis* / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008832:Microchemistry / Q000295:instrumentation* / Q000379:methods; D008839:Microelectrodes; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009824:Ointments; D010604:Pharmacy / Q000379:methods
chemical_list: D037742:Nanotubes, Carbon; D009824:Ointments; D004247:DNA; D004298:Dopamine