[Photodynamic therapy of experimental tumors using 5-aminolevulinic acid].
The photodynamic therapy (PDT) of Lewis carcinoma in c57Bl/6 mice and sarcoma 180 in random bred mice was carried out with 5-aminolaevulinic acid (ALA) used as a photosensitizer. It has been shown that ALA-PDT effectively inhibited the growth of Lewis carcinoma and sarcoma 180, decreased the frequency of metastatic spreading and the number of metastases to lung in mice with Lewis carcinoma. It is concluded that PDT with ALA is a potentially perspective method of tumor treatment.
Hamaliia
M F
MF
Kutsenok
V V
VV
Horobets'
O B
OB
Lozyns'kyĭ
M O
MO
Borysevych
A M
AM
Kholin
V V
VV
D000622:Aminolevulinic Acid / Q000494:pharmacology*; D000818:Animals; D018827:Carcinoma, Lewis Lung / Q000473:pathology / Q000628:therapy*; D051379:Mice; D008810:Mice, Inbred C57BL; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000473:pathology / Q000628:therapy*
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid