title: Estrogen receptor binding and alkylating properties of A-ring aromatic 17,20- and 20,21-epoxy-norpregnanediols: potential target selective antitumour agents.
authors.affiliation: Department of Chemistry, University of Technology, Loughborough, Leics, UK.
authors.forename: J C
authors.initials: JC
authors.lastname: Gill
authors.forename: S E
authors.initials: SE
authors.lastname: Khan
authors.forename: P M
authors.initials: PM
authors.lastname: Lockey
authors.forename: B A
authors.initials: BA
authors.lastname: Marples
authors.forename: J R
authors.initials: JR
authors.lastname: Traynor
mesh_terms: D000970:Antineoplastic Agents; D002470:Cell Survival / Q000187:drug effects; D015195:Drug Design; D004852:Epoxy Compounds; D004958:Estradiol / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D009650:Norpregnanes / Q000737:chemistry / Q000494:pharmacology*; D011960:Receptors, Estrogen / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D004852:Epoxy Compounds; D009650:Norpregnanes; D011960:Receptors, Estrogen; D004958:Estradiol