Clinical application of computed tomography for the diagnosis of feline hepatic lipidosis.
The usefulness of computed tomography (CT) for the diagnosis of feline hepatic lipidosis (FHL) was evaluated. Liver CT number was 54.7+/-5.6 HU (mean+/-SD) in 26 healthy cats. We fast 6 healthy cats for 72 hr to induced FHL experimentally and the cats were assessed by CT and serum biochemical analysis. Liver CT number of the six cats was 53.8+/-3.0 HU before fasting, 46.8+/-2.4 HU after fasting, and 50.2+/-3.6 HU two weeks after restarted feeding. The decreased CT number was associated with the elevation of serum non-esterified fatty acid (NEFA) and beta-hydroxybutyrate levels. These results indicate that measurement of CT number of the liver is an effective procedure for the diagnosis of FHL.
Nakamura
Momoko
M
Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology, Japan.
Chen
Hui-Min
HM
Momoi
Yasuyuki
Y
Iwasaki
Toshiroh
T
D020155:3-Hydroxybutyric Acid / Q000097:blood; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D005230:Fatty Acids, Nonesterified / Q000097:blood; D008064:Lipidoses / Q000175:diagnosis / Q000662:veterinary*; D008107:Liver Diseases / Q000175:diagnosis / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*
D005230:Fatty Acids, Nonesterified; D020155:3-Hydroxybutyric Acid