title: [Percutaneous large core breast biopsy].
abstract: Percutaneous large core biopsy of the breast with a 14-gauge needle, supported by sonographic and mammographic procedures, shows a high degree of safety during the collection for benign and malignant lesions. All malignant diagnoses (B 5) with a portion of 44% (267/604) were confirmed surgically, whereby the typing with 79% and grading with 58% were congruent. In 3.3% (20/604), there was uncertainty (B 3 and B 4), with the necessity for further clarification by open biopsy. This was supported by the fact that in 10/16 operated cases carcinoma was found. In the B 2-category, with a portion of nearly 44% (264/604), four cases of cancer were verified--not due to a wrongly negative histology but to non-representative material. In 8.8% (53/604), a questionable representative histology (B 1) occurred, but no cancer was found after surgical intervention (n=7). The indication for surgery is not only the punch biopsy result, but additionally negative histology and suspect or malignant clinical findings.
authors.affiliation: Gemeinschaftspraxis Pathologie, Starnberg, Germany. k.prechtel@t-online.de
authors.forename: K
authors.initials: K
authors.lastname: Prechtel
authors.forename: J
authors.initials: J
authors.lastname: de Waal
authors.forename: A
authors.initials: A
authors.lastname: Nerlich
authors.forename: D
authors.initials: D
authors.lastname: Hölzel
authors.forename: J
authors.initials: J
authors.lastname: Weitz
mesh_terms: D001706:Biopsy / Q000295:instrumentation / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D009339:Needles; D015203:Reproducibility of Results