Ambulatory monitoring of aborted sudden cardiac death related to hypertrophic cardiomyopathy.
BACKGROUND
A 47-year-old woman with obstructive hypertrophic cardiomyopathy presented with chest pain that had persisted despite treatment with verapamil and alpha-receptor antagonists. The patient had no other significant cardiac symptoms, no history of hypertension, and no familial predisposition to hypertrophic cardiomyopathy or sudden cardiac death. A loud (grade III/VI), dynamic, systolic ejection murmur was noted that could be heard diffusely over the precordium.


METHODS
Radionuclide perfusion imaging, coronary angiography, intracoronary Doppler flow measurements, and ambulatory electrocardiographic monitoring.


METHODS
Obstructive hypertrophic cardiomyopathy, myocardial ischemia and sudden cardiac arrest.


RESULTS
Surgical myectomy and cardioverter-defibrillator implantation.
Vaglio
Joseph C
JC
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Sorajja
Paul
P
Gersh
Bernard J
BJ
D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D017023:Coronary Angiography; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000517:prevention & control; D017147:Defibrillators, Implantable; D015716:Electrocardiography, Ambulatory; D005260:Female; D006346:Heart Septum / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D014463:Ultrasonography; D014693:Ventricular Fibrillation / Q000175:diagnosis