title: Enamel matrix proteins associated with GTR and bioactive glass in the treatment of class III furcation in dogs.
abstract: This study investigated, both histologically and histometrically, the efficacy of enamel matrix derived proteins (EMD) associated with bioactive glass (BG) and an absorbable membrane in the treatment of class III furcation defects in mongrel dogs. After surgical defect creation and chronification, the lesions were randomly divided into three groups according to the treatment employed: Test Group 1--EMD + BG + membrane, Test Group 2--EMD + membrane and Control Group--BG + membrane. After a 90-day healing period, the dogs were sacrificed. The descriptive analysis and the histometric data showed similar results for the experimental groups in all studied parameters (MANOVA, p > 0.05). The association of Emdogain with bioglass and GTR, or with GTR only, showed similar results when compared with the ones obtained with bioglass associated with membrane in the treatment of class III furcation defects in dogs. The three modalities of treatment showed partial filling of the furcations, with bone and cementum regeneration limited to the apical portion of the defects.
authors.affiliation: Department of Diagnosis and Surgery, School of Dentistry of Araraquara, São Paulo State University.
authors.forename: José Marcos Alves
authors.initials: JM
authors.lastname: Fernandes
authors.forename: Rodrigo Otávio Citó César
authors.initials: RO
authors.lastname: Rego
authors.forename: Luis Carlos
authors.initials: LC
authors.lastname: Spolidorio
authors.forename: Rosemary Adriana Chiérici
authors.initials: RA
authors.lastname: Marcantonio
authors.forename: Elcio
authors.initials: E
authors.lastname: Marcantonio Júnior
authors.forename: Joni Augusto
authors.initials: JA
authors.lastname: Cirelli
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects / Q000502:physiology; D003739:Dental Cementum / Q000187:drug effects / Q000502:physiology; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D004285:Dogs; D017823:Furcation Defects / Q000473:pathology / Q000628:therapy*; D005898:Glass; D016557:Guided Tissue Regeneration, Periodontal
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins