Kikuchi's lymphadenitis (necrotizing lymphadenitis) and systemic lupus erythematosus: a case report.
A 26-year-old Indian lady was admitted for lower abdominal pain, diarrhoea, vomiting, fever and cough. The initial diagnosis was that of peritonitis secondary to ruptured or perforated viscus with lobar pneumonia. On laparotomy, she was found to have necrotizing or Kikuchi's lymphadenitis of the abdominal lymph nodes. The initial two antinuclear antibody (ANA) results came back negative. She was diagnosed to have systemic lupus erythematosus (SLE) when the third sample for ANA came back positive and the double-stranded DNA (dsDNA) antibody test was homogenously positive. This case illustrates a need to be aware that necrotizing lymphadenitis can precede the onset of systemic lupus erythematosus.
Fernandez
S H
SH
Department of Pathology, Hospital Sultanah Aminah, Johor Baru, Malaysia.
D000005:Abdomen; D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D004247:DNA / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes; D008199:Lymphadenitis / Q000150:complications / Q000473:pathology*; D009336:Necrosis; D010538:Peritonitis / Q000175:diagnosis
D000974:Antibodies, Antinuclear; D004247:DNA