title: Effect of hinge location on corneal sensation and dry eye after laser in situ keratomileusis for myopia.
abstract: OBJECTIVE
  To evaluate the effects of a superior or nasal hinge location on corneal sensation and dry eye after laser in situ keratomileusis (LASIK).
  
  
  METHODS
  Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.
  
  
  METHODS
  This prospective randomized masked study included 47 patients having bilateral myopic LASIK surgery. The first eye was randomly assigned to have a nasal or superior hinge flap; the fellow eye had the alternate location. Visual acuity, contrast sensitivity, corneal sensation, basic secretion test, tear film breakup time, conjunctival and corneal staining, and a subjective questionnaire were evaluated preoperatively and postoperatively at 1 week and 1, 3, and 6 months. The Wilcoxon signed rank test and paired t test were used for comparison.
  
  
  RESULTS
  Dry eye occurred with the same frequency in both groups. However, eyes with the nasal hinge had significantly better nasal sensation than those with the superior hinge (P<.05) at 1 month.
  
  
  CONCLUSIONS
  Better nasal corneal sensation was found at 1 month in the nasal hinge group but there was no difference in any other parameters measured.
authors.affiliation: Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. vromandt@musc.edu
authors.forename: David T
authors.initials: DT
authors.lastname: Vroman
authors.forename: Helga P
authors.initials: HP
authors.lastname: Sandoval
authors.forename: Luis E
authors.initials: LE
authors.lastname: Fernández de Castro
authors.forename: Terrance J
authors.initials: TJ
authors.lastname: Kasper
authors.forename: Mike P
authors.initials: MP
authors.lastname: Holzer
authors.forename: Kerry D
authors.initials: KD
authors.lastname: Solomon
mesh_terms: D000328:Adult; D003228:Conjunctiva / Q000473:pathology; D015350:Contrast Sensitivity; D003315:Cornea / Q000294:innervation / Q000473:pathology / Q000503:physiopathology*; D015352:Dry Eye Syndromes / Q000209:etiology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D012677:Sensation; D016037:Single-Blind Method; D013194:Staining and Labeling; D013524:Surgical Flaps / Q000294:innervation*; D011795:Surveys and Questionnaires; D013666:Tears / Q000378:metabolism; D013997:Time Factors