title: Anal localization as first manifestation of metastatic ductal breast carcinoma.
abstract: The incidence of extrahepatic gastrointestinal metastases from breast cancer is reported in the literature only as necroscopy studies (6-18%); they usually originate from lobular or a mixed ductal-lobular subtype. Nonspecific presenting symptoms, death of the patients caused by other more frequent metastases, and variable radiographic features mimicking primary neoplasms cause a clinical underestimation of this pathology. We report here a case of rectal metastasis from an invasive ductal carcinoma (IDC). This is to our knowledge, the first recorded instance of an anal metastasis from IDC.
authors.affiliation: Department of Surgical Oncology, Paul Strauss Cancer Institute, Strasbourg, France.
authors.forename: R
authors.initials: R
authors.lastname: Haberstich
authors.forename: J J
authors.initials: JJ
authors.lastname: Tuech
authors.forename: M
authors.initials: M
authors.lastname: Wilt
authors.forename: J F
authors.initials: JF
authors.lastname: Rodier
mesh_terms: D000368:Aged; D000077384:Anastrozole; D001005:Anus Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003082:Colectomy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D009570:Nitriles / Q000008:administration & dosage*; D035583:Rare Diseases; D018570:Risk Assessment; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage*
chemical_list: D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole