The c-kit (CD117) sequence variation M541L, but not N564K, is frequent in the general population, and is not associated with CML in Caucasians.
Krüger
S
S
Emig
M
M
Lohse
P
P
Ehninger
G
G
Hochhaus
A
A
Schackert
H K
HK
D019943:Amino Acid Substitution / Q000235:genetics; D014644:Genetic Variation; D005838:Genotype; D005858:Germany; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics*; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics*; D013045:Species Specificity; D044465:White People / Q000235:genetics*
D019009:Proto-Oncogene Proteins c-kit