title: [Validation of a questionnaire to estimate satisfaction with antiretroviral treatment: CESTA questionnaire].
abstract: BACKGROUND
  Assessment of patient satisfaction with antiretroviral therapy is generating increasing interest in clinical practice, since the outcome is directly related with compliance with therapy and its effectiveness. Currently, there is no validated patient satisfaction questionnaire to evaluate this factor as related to control of the disease.
  
  
  METHODS
  An "ad hoc" questionnaire--Cuestionario Español de Satisfacción con el Tratamiento Antiretroviral (CESTA), Spanish Antiretroviral Treatment Satisfaction Questionnaire--was developed to evaluate satisfaction in patients switching to a simplified regimen. In a second phase, the questionnaire was validated in an observational study including 321 patients divided into two cohorts (patients switching to a simplified regimen and patients maintaining the same regimen).
  
  
  RESULTS
  A total of 99% and 93% patients, respectively, completed the questionnaire at baseline and at the end-of-study visit. Cronbach's alpha coefficient for internal consistency and test-retest reliability were 0.82 and 0.69, respectively. Patients switching to a simplified regimen showed a statistically significant higher overall satisfaction score at the third-month visit than at baseline.
  
  
  CONCLUSIONS
  The CESTA questionnaire is a valid instrument for use in clinical practice and provides valuable information on patient satisfaction with antiretroviral therapy.
authors.affiliation: Servicio de Medicina Interna, Hospital de Móstoles, Madrid, Spain.
authors.forename: Emilia
authors.initials: E
authors.lastname: Condes
authors.forename: Koldo
authors.initials: K
authors.lastname: Aguirrebengoa
authors.forename: David
authors.initials: D
authors.lastname: Dalmau
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Estrada
authors.forename: Luis
authors.initials: L
authors.lastname: Force
authors.forename: Miguel
authors.initials: M
authors.lastname: Górgolas
authors.forename: Xavier
authors.initials: X
authors.lastname: Badia
authors.forename: Daniel
authors.initials: D
authors.lastname: Podzamczer
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D015331:Cohort Studies; D004334:Drug Administration Schedule; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data; D017060:Patient Satisfaction; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents