[Composite template membranes as synthetic receptor systems 1. Preparation, specificity and template effect].
Molecularly impregnated membranes for selective recognizing of adenosine 3',5'-cyclic monophosphate (cAMP) were obtained and their separation properties were studied. Composite polyvinylidenfluoride microfiltration membranes covered with a thin layer of polymer impregnated with cAMP were prepared using photoinitiated copolymerization of dimethylaminoethylmethacrylate as a functional monomer and trimethylolpropane thrimethacrylate as a cross-linker in the presence of cAMP as a template. It was concluded that the ability of MIP membranes to selective binding of cAMP is a result of both specific shape and dimension of the recognizing site as well as specific interactions between functional groups responsible for selective template binding inside the receptor site.
Kochkodan
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Honcharuk
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D000242:Cyclic AMP / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008567:Membranes, Artificial; D011108:Polymers / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
D008567:Membranes, Artificial; D011108:Polymers; D000242:Cyclic AMP