title: Sinistral snails and gentlemen scientists.
abstract: A single gene mutation can cause a complete left-to-right and right-to-left inversion of the body axis. This mutation exemplifies a large class of so-called maternal effect genes that regulate key events during early development. This principle was first established nearly one hundred years ago, principally by the work of amateur naturalists.
authors.affiliation: Wellcome/Cancer Research UK Institute, Cambridge CB2 1QN, United Kingdom. jbg.1000@hermes.cam.ac.uk
authors.forename: J B
authors.initials: JB
authors.lastname: Gurdon
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000235:genetics; D004527:Egg Proteins / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation; D012908:Snails / Q000033:anatomy & histology*
chemical_list: D004527:Egg Proteins