title: Cutaneous thermal sensitivity in diabetic neuropathy.
abstract: BACKGROUND
  The goal of this investigation was to determine if cutaneous thermal sensitivity could be used as a discriminator of peripheral neuropathy in diabetic subjects who were sensate to the Semmes-Weinstein 5.07 monofilament.
  
  
  METHODS
  Sixty adult subjects were separated into two groups. The control group (A) was composed of 30 young healthy individuals without a history of diabetes. The focus group (B) was composed of 26 individuals with adult onset diabetes and four with juvenile onset. All of the subjects underwent thermal sensitivity testing in peripheral nerve root dermatomes of their hands and feet. Testing was performed with custom devices fabricated from materials with different thermal conduction capacities (copper, steel, glass, and plastic). Similar tests were performed with glass tubes containing heated or cooled water to develop a range of thermal sensitivity for the subjects.
  
  
  RESULTS
  There was a strong relationship between cold perception and stimulation with the copper probe in dermatomes of the radial nerve of the upper limb and the superficial peroneal dermatome of the lower limb.
  
  
  CONCLUSIONS
  Thermal sensitivity to copper and cold stimulation may be more discriminative and have a higher threshold than sensitivity to the Semmes-Weinstein monofilament. This simple method may have a role in the early detection of peripheral neuropathy in adult-onset diabetes mellitus.
authors.affiliation: Universidade Federal de Sao Paolo Orthopaedic Surgery, Sao Paolo, Brazil.
authors.forename: Fabio
authors.initials: F
authors.lastname: Batista
authors.forename: Michael S
authors.initials: MS
authors.lastname: Pinzur
authors.forename: Caio A S
authors.initials: CA
authors.lastname: Nery
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003080:Cold Temperature; D003929:Diabetic Neuropathies / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D012867:Skin / Q000503:physiopathology*; D013697:Thermosensing / Q000502:physiology*