title: Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis.
abstract: The cell envelopes of actinomycetes contain lipidated macroamphiphiles, of which the most extensively characterised are the lipoarabinomannans of mycobacteria and related bacteria. We have investigated the mycolic acid-containing actinomycete Gordonia bronchialis and identified the presence of a lipoarabinomannan-like lipoglycan. The extraction and purification procedures recovered a second amphiphilic fraction with properties suggesting a phosphatidylinositol mannoside, consistent with studies of other Gordonia species.
authors.affiliation: Department of Infection, Immunity and Inflammation, Leicester University, Medical Sciences Building, University Road, PO Box 138, LE1 9HN, Leicester, UK.
authors.forename: Natalie J
authors.initials: NJ
authors.lastname: Garton
authors.forename: Iain C
authors.initials: IC
authors.lastname: Sutcliffe
mesh_terms: D005227:Fatty Acids / Q000032:analysis; D033601:Gordonia Bacterium / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000302:isolation & purification*; D019308:Palmitic Acid / Q000032:analysis; D013229:Stearic Acids / Q000032:analysis
chemical_list: D005227:Fatty Acids; D008070:Lipopolysaccharides; D013229:Stearic Acids; C050016:lipoarabinomannan; D019308:Palmitic Acid; C031183:stearic acid; C026082:tuberculostearic acid; C013102:margaric acid