Design, synthesis and evaluation of near-infrared fluorescent pH indicators in a physiologically relevant range.
Removal of a hydroxylsulfonylbutyl arm from indocyanine green dye produced a pH-sensitive near-infrared (NIR) fluorescent indicator that is useful at physiological range.
Zhang
Zongren
Z
Department of Radiology, Washington University, St. Louis, Missouri 63110, USA.
Achilefu
Samuel
S
D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007208:Indocyanine Green / Q000737:chemistry; D007259:Infrared Rays; D015394:Molecular Structure
D005456:Fluorescent Dyes; D007208:Indocyanine Green