title: [The effect of muscovite on the quality of gastric ulcer healing].
abstract: OBJECTIVE
  To explore the effect of muscovite on the quality of gastric ulcer healing.
  
  
  METHODS
  Gastric ulcers were produced in male rats by serosal application of acetic acid. Rats were gavaged for 14 days with saline, omeprazole and muscovite starting 3 days after ulcer induction. Then the tissue and blood samples were obtained and measured.
  
  
  RESULTS
  In the muscovite group, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, EGF, bFGF were enhanced, and the express of EGFR was stronger.
  
  
  CONCLUSIONS
  Muscovite can promote the gastric ulcer healing and improve the quality of gastric ulcer healing.
authors.affiliation: Institute of Clinic Medicine Research of Sir Run Run Shaw, Zhejiang University, Hangzhou 310016, China. sijm@163.net
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Si
authors.forename: Yun
authors.initials: Y
authors.lastname: Qian
authors.forename: Jia-Guo
authors.initials: JG
authors.lastname: Wu
mesh_terms: D000538:Aluminum Silicates / Q000494:pharmacology*; D000818:Animals; D015232:Dinoprostone / Q000097:blood; D066246:ErbB Receptors / Q000378:metabolism*; D016222:Fibroblast Growth Factor 2 / Q000378:metabolism; D005753:Gastric Mucosa / Q000473:pathology / Q000503:physiopathology; D006595:Hexosamines / Q000378:metabolism; D008297:Male; D008419:Materia Medica / Q000494:pharmacology*; D009093:Mucus / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology
chemical_list: D000538:Aluminum Silicates; D006595:Hexosamines; D008419:Materia Medica; D016222:Fibroblast Growth Factor 2; D066246:ErbB Receptors; D015232:Dinoprostone