title: [About a correlation between calcium ion concentration (Ca2+) in the blood and the state of physiological functions in animals in deep cooling].
abstract: The changes in physiological functions of the organism (respiration, functions of the heart and vessels, thermoregulation) were studied. The concentration of Ca2+ ions in the blood of white rats was determined by the ion-selective electrodes at various stages of hypothermia. The aim of the study was to reveal changes in the blood concentration of ionized calcium in animals during their gradual cooling. In deep hypothermia (16 degrees C), calcium ion concentration in the blood increased by 30% against the norm which coincides with arrest of the cold shivering and lung ventilation. An increased content of Ca2+ in the blood is supposed to result in an increase in the content of these ions in the intercellular liquid and in the nervous cells, which is one of the reasons for the cold paralysis of the respiration and thermoregulation centers.
authors.forename: G S
authors.initials: GS
authors.lastname: Fedorov
authors.forename: I L
authors.initials: IL
authors.lastname: Potekhina
authors.forename: K P
authors.initials: KP
authors.lastname: Ivanov
mesh_terms: D000818:Animals; D001833:Body Temperature Regulation; D002118:Calcium / Q000097:blood*; D007036:Hypothermia, Induced; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012119:Respiration
chemical_list: D002118:Calcium