title: [Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri].
abstract: The main pharmacological constituents of Chinese traditional medicine herb Cnidium monnieri are coumarin compounds and volatile oil. In addition, it contains monoterpene polyols, glucides, as well as recently discovered sesquiterpene components. In recent years, rather active investigations of its anti-tumor were performed at home and abroad. C. monnieri possesses multi-aspect and comprehensive anti-tumor functions, involving directly tumor-inhibitory activity, anti-mutagenicity, reversing multi-drug tolerance of tumor, as well as improving immune functions and so on. In this review, chemical constituents, anti-tumor activities and relevant investigations of Fructus Cnidii were summarized recent decade.
authors.affiliation: Chinese Academy of Medical Sciences, Tradiation Medica Institute, Tianjin 300192, China. zhouzewei666@yahoo.com.cn
authors.forename: Ze-wei
authors.initials: ZW
authors.lastname: Zhou
authors.forename: Pei-xun
authors.initials: PX
authors.lastname: Liu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D031048:Cnidium / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D011564:Furocoumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D003374:Coumarins; D004365:Drugs, Chinese Herbal; D011564:Furocoumarins; C030123:coumarin; C031534:imperatorin; C046627:osthol