Acromegaly secondary to growth hormone releasing hormone secretion.
BACKGROUND
Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare.


OBJECTIVE
To report a case of acromegaly diagnosed in 1984 and assumed to be pituitary in origin. Sixteen years later, the cause was found to be a GHRH secreting neuroendocrine pancreatic tumour.


METHODS
A case report.


CONCLUSIONS
Although ectopic GHRH production is very rare, endocrinologists should be aware of this possibility in acromegaly patients if a pituitary tumour was not detected using pituitary imaging.
Agha
Department of Endocrinology, James Connolly Memorial Hospital, Dublin, Ireland. amaragha@yahoo.com
Farrell
L
L
Downey
P
P
Keeling
P
P
Leen
E
E
Sreenan
S
S
D000172:Acromegaly / Q000175:diagnosis / Q000503:physiopathology*; D000328:Adult; D005260:Female; D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging; D018358:Neuroendocrine Tumors / Q000503:physiopathology*; D010190:Pancreatic Neoplasms / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed
D013007:Growth Hormone-Releasing Hormone