title: Community acquired pneumonia (CAP) caused by Cryptococcus neoformans in a healthy individual.
abstract: A 41-y-old male had been diagnosed as having community acquired pneumonia (CAP) with consolidations in the chest radiograph, fever and cough. Since clarithromycin and ss-lactam agents were not effective, bronchoscopic examination was performed. Indian ink staining of bronchial wash smears revealed yeast-like cells with a thick capsule, and Cryptococcus neoformans was isolated several d later. Serum glucuronoxylomannan antigen was > or = x 1024. The patient was treated with itraconazole for 16 weeks.
authors.affiliation: Second Department of Internal Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Nakamura
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Higashiyama
authors.forename: Katsunori
authors.initials: K
authors.lastname: Yanagihara
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ohno
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hirakata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shikuwa
authors.forename: Yohei
authors.initials: Y
authors.lastname: Mizuta
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Tashiro
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003453:Cryptococcosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D011014:Pneumonia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole