[Biochemical markers of bone remodeling].
Bone markers are aimed to assess bone cells activity. Some are specific of bone formation (osteocalcin, bone alkaline phosphatase, extension peptides of type I procollagen); others are specific of bone resorption (deoxypyridinoline and peptidebound forms.). Their main applications are: evaluation of fracture risk and follow-up of antiosteoporotic treatments. Their use in clinical practice is difficult: choice of the most appropriate bone marker, relevance of changes, and may require the specialist's opinion.
Briot
K
K
Service de rhumatologie, hôpital Cochin (APHP), université Paris-Descartes, France.
Roux
C
C
D000135:Acid Phosphatase / Q000032:analysis / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000032:analysis / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis* / Q000378:metabolism; D016723:Bone Remodeling / Q000502:physiology*; D001862:Bone Resorption / Q000175:diagnosis / Q000628:therapy; D003094:Collagen / Q000032:analysis / Q000378:metabolism; D024042:Collagen Type I; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008593:Menopause; D015675:Osteocalcin / Q000032:analysis / Q000378:metabolism; D010024:Osteoporosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D010455:Peptides / Q000032:analysis / Q000378:metabolism; D012307:Risk Factors
D015415:Biomarkers; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D015675:Osteocalcin; D003094:Collagen; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase