title: Histomorphometric evaluation of human sinus floor augmentation healing responses to placement of calcium phosphate or Ricinus communis polymer associated with autogenous bone.
abstract: BACKGROUND
  Prosthetic rehabilitation of the posterior maxilla with dental implants is often difficult because of proximity to the maxillary sinus and insufficient bone height. Maxillary sinus floor augmentation procedures aim to obtain enough bone with an association between biomaterials and autogenous bone.
  
  
  OBJECTIVE
  The purpose of this study was to evaluate histomorphometrically two grafting materials (calcium phosphate and Ricinus communis polymer) used in maxillary sinus floor augmentation associated with autogenous bone.
  
  
  METHODS
  Biopsies were taken from 10 consecutive subjects (mean age 45 years) 10 months after maxillary sinus floor augmentation. The sinus lift was performed with a mixture of autogenous bone and R. communis polymer or calcium phosphate in a 1:2 proportion. Routine histologic processing and staining with hematoxylin and eosin were performed.
  
  
  RESULTS
  The histomorphometric analysis indicated satisfactory regenerative results in both groups for a mean of bone tissue in the grafted area (44.24 +/- 13.79% for the calcium phosphate group and 38.77 +/- 12.85% for the polymer group). Histologic evaluation revealed the presence of an inflammatory infiltrate of mononuclear prevalence that, on average, was nonsignificant. The histologic sections depicted mature bone with compact and cancellous areas in both groups.
  
  
  CONCLUSIONS
  The results indicated that both graft materials associated with the autogenous bone were biocompatible, although both were still present after 10 months.
authors.affiliation: Department of Periodontology, Dental School at Araraquara, State University of São Paulo, UNESP, Araraquara, SP, Brazil.
authors.forename: Rodolfo Jorge
authors.initials: RJ
authors.lastname: Boëck-Neto
authors.forename: Mário Francisco Real
authors.initials: MF
authors.lastname: Gabrielli
authors.forename: Jamil Awad
authors.initials: JA
authors.lastname: Shibli
authors.forename: Elcio
authors.initials: E
authors.lastname: Marcantonio
authors.forename: Raphael Carlos Comelli
authors.initials: RC
authors.lastname: Lia
authors.forename: Elcio
authors.initials: E
authors.lastname: Marcantonio
mesh_terms: D000328:Adult; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001704:Biopolymers; D001853:Bone Marrow / Q000473:pathology; D001861:Bone Regeneration / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation; D002130:Calcium Phosphates / Q000627:therapeutic use*; D005260:Female; D006253:Haversian System / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007963:Leukocytes, Mononuclear / Q000473:pathology; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery*; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D010006:Osteoblasts / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology; D012116:Resins, Plant / Q000627:therapeutic use*; D012278:Ricinus; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D018786:Bone Substitutes; D002130:Calcium Phosphates; D012116:Resins, Plant; C509865:poliquil; C020243:calcium phosphate