[Acute renal failure due to abdominal compartment syndrome].
OBJECTIVE
To observe the effect of intra-abdominal hypertension on renal function.


METHODS
30 intra-abdominal hypertension patients, 26 mals and 4 femals, age 42 +/- 17, were observed. Intra-abdominal pressure, mean arterial pressure, central venous pressure and serum creatinine were recorded and tested at the same time every day.


RESULTS
When the intra-abdominal pressure increased, the urine output decreased (from 78 ml/h +/- 26 ml/h to 31 ml/h +/- 11 ml/h, P < 0.01), serum creatinine increased (from 110 mmol/L +/- 98 mmol/L to 224 mmol/L +/- 147 mmol/L, P < 0.01) with high central venous pressure (6.0 mm Hg +/- 2.1 mm Hg to 8.8 mm Hg +/- 2.5 mm Hg, 1 mm Hg = 0.133 kPa, P < 0.01) and high mean arterial pressure (from 79 mm Hg +/- 8 mm Hg to 86 mm Hg +/- 10 mm Hg, P < 0.01). There is a significant negative correlation between the intra-abdominal hypertension and urine output (r = -0.747, P < 0.01), and a significant positive correlation between the intra-abdominal hypertension and serum creatinine (r = 0.816, P < 0.01). During the ICU stay, 12 patients died, amoung which 8 died from multiple organ dysfunction due to septicemia and 4 died from abdominal hemorrhage.


CONCLUSIONS
Intra-abdominal hypertension is correlated with lower urine output and increased blood creatinine significantly, and these results can be inversed when the intra-abdominal pressure decreases.
Ma
Ying-min
YM
Department of Emergence, General Hospital of People's Liberation Army, Beijing 100853, China.
Qian
Chao
C
Xie
Fei
F
Zhou
Fei-hu
FH
Pan
Liang
L
Song
Qing
Q
D000005:Abdomen / Q000503:physiopathology; D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D003161:Compartment Syndromes / Q000150:complications*; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011312:Pressure