Effect of kosmotropicity of ionic liquids on the enzyme stability in aqueous solutions.
This paper examined the effect of several pyridinium and imidazolium-based ionic liquids (ILs) on the protease stability in aqueous solutions. In general, the enzyme was found quite active at low concentrations of hydrophilic ILs. In aqueous environment, the enzyme was stabilized by the kosmotropic anions (such as CF3COO- and CH3COO-) and chaotropic cations (such as [BuPy]+ and [EMIM]+), but was destabilized by chaotropic anions (such as tosylate and BF4-) and kosmotropic cations (such as [BMIM]+).
Zhao
Hua
H
Chemistry Program, Department of Natural Sciences and Mathematics, Savannah State University, Savannah, GA 31404, USA. zhaoh@savstate.edu
Olubajo
Olarongbe
O
Song
Zhiyan
Z
Sims
Artez L
AL
Person
Terra E
TE
Lawal
Rasheed A
RA
Holley
Ladena A
LA
D019342:Acetic Acid / Q000737:chemistry; D001230:Aspergillus / Q000201:enzymology*; D004795:Enzyme Stability; D007093:Imidazoles / Q000737:chemistry*; D007477:Ions; D010447:Peptide Hydrolases / Q000737:chemistry / Q000378:metabolism*; D011725:Pyridines / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D013997:Time Factors; D014269:Trifluoroacetic Acid / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D007093:Imidazoles; D007477:Ions; D011725:Pyridines; D012996:Solutions; D014867:Water; D014269:Trifluoroacetic Acid; D010447:Peptide Hydrolases; D019342:Acetic Acid