title: [Investigation of TiO2 photocatalytic degradation of bovine serum albumin].
abstract: The present paper reports photocatalytic degradation of bovine serum albumin (BSA) by TiO2 under near UV (365 nm) irradiation. Ultraviolet-Visible spectrometry, FTIR spectrometry and HPLC were used to study the degradation and characterize the final degradation products. It was found that under near UV irradiation, BSA (0.1 g x L(-1)) can be totally degraded to small fragments by TiQ2 in 5 h. Total mineralization of BSA (93.5%) is reached after reacting for 40 h. C, N and S in BSA are mineralized to give CO2, NO3- and SO4(2-). It is suggested that the degradation of BSA happens in two steps: first to small fragments, then further mineralized to small inorganic molecule. The absence of UV irradiation or TiQ2 can only lead to partial degradation of BSA (30%) in 5 h and no CO2 is observed even in longer reaction time.
authors.affiliation: Research Institute of Photocatalysis, Fuzhou University, Fuzhou 350002, China.
authors.forename: Gui-qin
authors.initials: GQ
authors.lastname: Yang
authors.forename: Zhao-hui
authors.initials: ZH
authors.lastname: Li
authors.forename: Zhang-xiang
authors.initials: ZX
authors.lastname: Lin
authors.forename: Xu-xu
authors.initials: XX
authors.lastname: Wang
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Xian-zhi
authors.initials: XZ
authors.lastname: Fu
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000737:chemistry / Q000378:metabolism; D002384:Catalysis / Q000528:radiation effects; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D009566:Nitrates / Q000737:chemistry / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000737:chemistry* / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013431:Sulfates / Q000737:chemistry / Q000378:metabolism; D013997:Time Factors; D014025:Titanium / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D009566:Nitrates; D013431:Sulfates; D002245:Carbon Dioxide; C009495:titanium dioxide; D012710:Serum Albumin, Bovine; D014025:Titanium