Reduction of 2,3-dihydroisoxazoles to beta-amino ketones and beta-amino alcohols.
[chemical reaction: see text]. We report the reduction of 2,3-dihydroisoxazoles to beta-amino ketones and beta-amino alcohols. The latter are obtained in high diastereoselectivity with preference for the syn isomer.
Aschwanden
Patrick
P
Laboratorium für Organische Chemie, ETH Hönggerberg, CH-8093 Zürich, Switzerland.
Kvaernø
Lisbet
L
Geisser
Roger W
RW
Kleinbeck
Florian
F
Carreira
Erick M
EM