[New aspects of corneal pachymetry in congenital glaucoma and pediatric aphakic glaucoma].
BACKGROUND
Knowledge of individual corneal thickness in individual eyes is proving to be more and more crucial for correcting Goldmann applanation tonometry, as well as to assess its predictive value regarding the possible progression of glaucomatous damage. It has become an important factor in determining appropriate glaucoma therapy. Only few pachymetric data exist about eyes with congenital or secondary pediatric aphakic glaucoma.


METHODS
12 eyes with congenital glaucoma (6 patients, mean age 3.3 years, mean 3.9 previous operations) and 7 eyes with secondary pediatric aphakic glaucoma (4 patients, mean age 14.8 years, mean 3 previous operations) without clinical signs of corneal decompensation were investigated by ultrasound pachymetry.


RESULTS
Eyes with glaucoma due to aphakia had a mean corneal thickness of 708 +/- 77.3 microm. Mean corneal thickness of the eyes with congenital glaucoma was 688.1 +/- 115.9 microm, which is far above the values known from the literature. Two eyes, which had a central corneal thickness of 646 microm and 640 microm, presented with a localised paracentral corneal thickness of only 402 microm and 405 microm, respectively, correlating with microscopic descemet scars.


CONCLUSIONS
Congenital glaucoma and the pediatric aphakic glaucoma present with very heterogeneous clinical pictures. Especially for congenital glaucoma, this is confirmed by the high interindividual, but also intraindividual, variability of corneal pachymetry.
Jordan
J F
JF
Zentrum für Augenheilkunde, Universität zu Köln. jens.jordan@uk-koeln.de
Dietlein
T S
TS
Dinslage
S
S
Krieglstein
G K
GK
D000293:Adolescent; D001036:Aphakia, Postcataract / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D019781:Corneal Topography / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005901:Glaucoma / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D012680:Sensitivity and Specificity; D014463:Ultrasonography