title: Histopathology of lymph nodal tuberculosis--university hospital experience.
abstract: Fifty-nine cases of tuberculous cervical lymphadenitis were analysed histologically. Characteristic epithelioid cell granulomas were seen in all the cases with central areas of caseation necrosis in 96.6% (57/59) of these cases. The diagnosis of tuberculosis was further established by the demonstration of acid-fast bacilli (AFB) in the tissue sections in 29 cases. These AFB, although occasional, were found more frequently within the epithelioid cells as compared with other zones of the granuloma. There was no significant association between necrosis and bacillary content. We conclude that light microscopical assessment is still a useful screening method to diagnose tuberculosis in cases of cervical lymphadenopathy.
authors.affiliation: Department of Pathology, Faculty of Medicine, University of Malaya, 59100 Kuala Lumpur, Malaysia.
authors.forename: P
authors.initials: P
authors.lastname: Jayalakshmi
authors.forename: A K
authors.initials: AK
authors.lastname: Malik
authors.forename: H S
authors.initials: HS
authors.lastname: Soo-Hoo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D015622:Epithelioid Cells / Q000382:microbiology / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000382:microbiology / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000254:growth & development / Q000302:isolation & purification; D014388:Tuberculosis, Lymph Node / Q000382:microbiology / Q000473:pathology