Rapid chloride analysis using miniaturised isotachophoresis.
A new design of miniaturised separation device for performing isotachophoresis (ITP) has been produced. The device contains a simple arrangement of channels comprising a single separation channel with a 'double T' injection geometry. The device was produced in poly(methyl methacrylate) and incorporates an on-column conductivity detector. A new electrolyte system was developed to enable the rapid determination of chloride to be made. This electrolyte system uses a leading ion of 3.5 mM nitrate at pH 3.0 with 0.5 mM indium(III) added as a complexing agent. Use of this electrolyte system with the new separation device allowed chloride samples to be analysed in under 100 s, with a limit of detection (LOD) calculated to be 2.2 mg l(-1).
Prest
Jeff E
JE
School of Chemical Engineering and Analytical Science, The University of Manchester, UK. j.prest@manchester.ac.uk
Baldock
Sara J
SJ
Fielden
Peter R
PR
Goddard
Nicholas J
NJ
Mohr
Stephan
S
Treves Brown
Bernard J
BJ
D002712:Chlorides / Q000032:analysis*; D004573:Electrolytes; D004586:Electrophoresis / Q000295:instrumentation / Q000379:methods*; D008904:Miniaturization; D009566:Nitrates
D002712:Chlorides; D004573:Electrolytes; D009566:Nitrates