title: Development of an adenocarcinoma of the esophagus 22 years after primary repair of a congenital atresia.
abstract: Esophageal cancer development after previous atresia repair is extremely rare in young patients. We present the clinical course of a patient who developed an adenocarcinoma of the esophagus at the age of 22 years, after repair of a tracheoesophageal fistula with esophageal atresia in the neonatal period. She developed a stricture of the esophageal anastomosis requiring frequent dilatations. Six years after an antireflux procedure because of a difficult treatable severe gastroesophageal reflux, an advanced adenocarcinoma was detected at the site of the end-to-end anastomosis of the previous atresia.
authors.affiliation: Department of Surgical Oncology, University Medical Center Groningen (UMCG), 9700 RB Groningen, The Netherlands.
authors.forename: Bareld B
authors.initials: BB
authors.lastname: Pultrum
authors.forename: Charles M
authors.initials: CM
authors.lastname: Bijleveld
authors.forename: Zacharias J
authors.initials: ZJ
authors.lastname: de Langen
authors.forename: John Th M
authors.initials: JT
authors.lastname: Plukker
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000714:Anastomosis, Surgical; D004933:Esophageal Atresia / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000473:pathology; D004947:Esophagus / Q000601:surgery; D005260:Female; D005764:Gastroesophageal Reflux; D006801:Humans; D013997:Time Factors