[Studies on chemical constituents in leaf of Isatis indigotica].
OBJECTIVE
To study the chemical constituents of the leaf of Isatis indigotica.


METHODS
Chromatography and spectral analysis were respectively used to isolate and identify the constituents.


RESULTS
Three compounds were isolated from the ethanol extracts of theleaf of I. indigotica, and identified as indirubin, tryptanthrin and L-pyroglutamic acid.


CONCLUSIONS
L-pyroglutamic acid was isolated from the genus for the first time, and tryptanthrin was isolated from the leaf of this plant for the first time.
Ruan
Jin-Lan
JL
College of Pharmacy, Tongji Medical Center of Huazhong University of Science and Technology, Wuhan 430030, China. jinlan5952@hotmail.com
Zou
Jian-Hua
JH
Cai
Ya-Ling
YL
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification; D031219:Isatis / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011761:Pyrrolidonecarboxylic Acid / Q000737:chemistry / Q000302:isolation & purification*; D011799:Quinazolines / Q000737:chemistry / Q000302:isolation & purification*
D004365:Drugs, Chinese Herbal; D007211:Indoles; D011799:Quinazolines; C046243:tryptanthrine; D011761:Pyrrolidonecarboxylic Acid; C027185:indirubin