An update on publicly funded multisite trials in pediatric psychopharmacology.
In the last 10 years, the National Institute of Mental Health has funded a number of multisite clinical trials in pediatric psychopharmacology. Trials have been completed or are in progress in attention-deficit hyperactivity disorder, depression, autism, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and other anxiety disorders. Direct comparison between different treatment modalities, such as pharmacotherapy and psychotherapy, alone or in combination, has been the focus of a number of these studies, to inform clinicians and families of the relative therapeutic benefits of alternative interventions. This article presents a brief overview of these studies.
Vitiello
Benedetto
B
National Institute of Mental Health, Room 7147, 6001 Executive Boulevard, MSC 9633, Bethesda, MD 20892-9633, USA. bvitiell@mail.nih.gov
D002648:Child; D002665:Child Psychiatry / Q000191:economics*; D002986:Clinical Trials as Topic / Q000191:economics*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000191:economics*; D015337:Multicenter Studies as Topic / Q000191:economics*; D011600:Psychopharmacology / Q000191:economics*; D011634:Public Health