title: [Risk factors for prosthesis exposure in treatment of genital prolapse via the vaginal approach].
abstract: OBJECTIVE
  Prosthetic reinforcement in the surgical repair of pelvic prolapse by the vaginal approach is currently on the increase. However, this technique is not without tolerance-related problems. The most frequently described complication is prosthesis exposure, including erosion and delayed healing. It is independent of a granuloma and a major infection as pelvic cellulitis. Its mechanism is associated with defective vaginal healing. The purpose of our study is to define the risk factors for exposure of the prosthetic material.
  
  
  METHODS
  Two hundred and seventy-seven medical records relating to patients undergoing surgery due to pelvic prolapse were included in our study. The treatment of genital prolapse was managed via the vaginal approach with polypropylene mesh. This is a continuous, retrospective study conducted over a period of 24 months.
  
  
  RESULTS
  Thirty-four cases of prosthesis exposure were observed in the 2 months following surgery, which represents an incidence of 12.27%. The risk factors are concomitant hysterectomy [odds ratio 5.17 (P = 0.001)] and inverted T colpotomy [odds ratio 6.06 (P = 0.01)]. The protective factors are preservation of the uterus and the performance of a minor colpotomy in patients who had already undergone a hysterectomy or in those whose uterus had been preserved [odds ratio 5.16 (P = 0.0001)].
  
  
  CONCLUSIONS
  In our study, we have only found risk factors of operative protocol. In fact, other information as age, menopause status or medical history of the patient is not significant. The uterus must be preserved and the number and extent of colpotomies needed to insert the prosthesis must be limited.
authors.affiliation: Clinique de chirurgie gynécologique, hôpital Jeanne-de-Flandre, CHRU de Lille, France.
authors.forename: F
authors.initials: F
authors.lastname: Belot
authors.forename: P
authors.initials: P
authors.lastname: Collinet
authors.forename: P
authors.initials: P
authors.lastname: Debodinance
authors.forename: E
authors.initials: E
authors.lastname: Ha Duc
authors.forename: J-P
authors.initials: JP
authors.lastname: Lucot
authors.forename: M
authors.initials: M
authors.lastname: Cosson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020884:Colpotomy / Q000009:adverse effects*; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D008875:Middle Aged; D011126:Polypropylenes; D019919:Prosthesis Implantation / Q000295:instrumentation / Q000379:methods / Q000592:standards; D012189:Retrospective Studies; D012307:Risk Factors; D013526:Surgical Mesh; D017211:Treatment Failure; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*
chemical_list: D011126:Polypropylenes