[Clinical value of ultrasound guided transperineal prostate biopsy in detecting prostate cancer].
OBJECTIVE
To report our experience of ultrasound guided transperineal 6-core prostate biopsy (UG6CPB) in the diagnosis of prostate cancer (PCa).


METHODS
In a prospective study, we performed UG6CPB in 104 suspected PCa patients with tPSA more than 4 microg/L and analysed the positive rate and complications of the diagnostic approach.


RESULTS
PCa was detected in 24 of the 104 patients (23%), with low grade Gleason 2 to 4 in 3 cases (12.5%), intermediate grade Gleason 5 to 7 in 15 (62.5%) and high grade Gleason 8 to 10 in the remaining 6 (25%). Complications included temporary hematuria in 5 patients (4.8%), mild postbiopsy perineal discomfort in 5 (4.8%) and fever in 4 (3.8%). TPSA > or =10 microg/L, fPSA > or = 2 microg/L, fPSA/tPSA < 0.16, PSAD > or = 0.2 and prostate volume < 40 ml were the significant influencing factors of biopsy positive rate (P < 0.05).


CONCLUSIONS
UG6CPB is an exact and a safe way of detecting PCa.
Li
Gui-Zhong
GZ
Department of Urology, Beijing Jishuitan Hospital, Beijing 100035, China. lee_gz99@sohu.com
Liu
Liu
L
Huang
Guang-Lin
GL
Chen
Tao
T
Yan
Bing
B
Gao
Yan
Y
Luo
Fei
F
Liu
Ning
N
Wang
Jian-Wei
JW
Man
Li-Bo
LB
He
Feng
F
Wang
Hai
H
D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D008297:Male; D010502:Perineum; D011446:Prospective Studies; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography
D017430:Prostate-Specific Antigen