title: [The Vogt-Koyanagi-Harada syndrome: a rare differential diagnosis of uveitis in childhood. A case report taking into account the revised diagnostic criteria].
abstract: BACKGROUND
  The diagnosis of the multisystemic Vogt-Koyanagi-Harada (VKH) syndrome including ocular, neurological and dermatological manifestations is difficult due to the absence of diagnostic serological parameters and the variable onset of clinical signs and symptoms in the course of the disease.
  
  
  METHODS
  A 12 year old female patient was admitted to our clinic , presenting with bilateral choroiditis, vitiligo and episodes of headache. After having ruled out an underlying rheumatological or infectious disease, a VKH syndrome was suspected and effectively treated with systemic steroids. The initial diagnosis of VKH syndrome would not have been possible, if the existing diagnostic criteria had been applied.
  
  
  CONCLUSIONS
  As can be seen in the case of our patient, the existing diagnostic criteria of VKH syndrome may prove to be inadequate in diagnosing VKH syndrome, particularly at the onset of the disease. Considering, that early diagnosis and treatment is crucial in improving the outcome of the disease, current diagnostic criteria have been revised. Recent retrospective data suggest a higher sensitivity for the revised diagnostic criteria.
authors.affiliation: Universitätsklinikum, Medizinische Fakultät der Humboldt-Universität zu Berlin.
authors.forename: R
authors.initials: R
authors.lastname: Rieger
authors.forename: R
authors.initials: R
authors.lastname: Keitzer
authors.forename: U
authors.initials: U
authors.lastname: Pleyer
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards / Q000639:trends; D014605:Uveitis / Q000175:diagnosis; D014607:Uveomeningoencephalitic Syndrome / Q000145:classification* / Q000175:diagnosis*