A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus.
The antibacterial activity of Haplopappus uncinatus is attributed to a new clerodane diterpenoid, 18-acetoxy-cis-cleroda-3-en-15-oic acid (10 betaH, 16 xi 19 beta, 17beta, 20 alpha form) (1), isolated as a major component from the resinous exudates of its twigs and leaves, together with the inactive 3,5-dihydroxy-6,7,3',4'-tetramethoxyflavone, n-alkanes and a few sesquiterpenoids.
Urzúa
A
A
Facultad de Química y Biología, Universidad de Santiago, Casilla 40, Correo 33 Santiago, Chile. aurzuamoll44@yahoo.com
Jara
F
F
Tojo
E
E
Wilkens
M
M
Mendoza
L
L
Rezende
M C
MC
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D031206:Haplopappus; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D013329:Structure-Activity Relationship
D000890:Anti-Infective Agents; D004224:Diterpenes; D010936:Plant Extracts