Genital vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.
BACKGROUND
Genital vitiligo is common and has a deleterious effect on the psychosexual function of patients. It is well known that glabrous skin (non-hair-bearing skin such as below the ankles, genitalia, lips, distal ends of fingers) rarely responds to the therapy unless it has some residual pigment.


OBJECTIVE
The objective was to report genital vitiligo treated successfully by autologous, noncultured, melanocyte-keratinocyte cell transplantation.


METHODS
Three cases of clinically stable genital vitiligo were treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.


RESULTS
All lesions treated repigmented almost completely. All patients were very satisfied with the excellent cosmetic results.


CONCLUSIONS
Autologous, noncultured melanocyte-keratinocyte cell transplantation may be an effective surgical treatment for management of genital vitiligo.
Mulekar
Sanjeev V
SV
National Center for Vitiligo and Psoriasis, Riyadh, Saudi Arabia. dr_mulekar@vsnl.com
Al Issa
Ahmed
A
Al Eisa
Abdullah
A
Asaad
Marwan
M
D000328:Adult; D017690:Cell Transplantation / Q000379:methods; D006801:Humans; D015603:Keratinocytes / Q000637:transplantation*; D008297:Male; D008544:Melanocytes / Q000637:transplantation*; D010413:Penis; D016038:Skin Transplantation / Q000379:methods*; D014182:Transplantation, Autologous; D014820:Vitiligo / Q000601:surgery*