[Isolated pathogen microorganisms in respiratory samples from children with cystic fibrosis].
Cystic Fibrosis (CF) is characterized by a dysfunction of the exocrine secretion glands. The first symptoms often appear in the respiratory system which constitutes one of the most important morbimortality causes in these patients. Chronic respiratory tract colonization is caused mainly by bacteria such as Staphylococcus aureus, Haemophilus spp. and Pseudomonas aeruginosa. Respiratory samples from patients with CF (age group: 4 months to 11 years) were analyzed from November 2001 to August 2004. The most frequently isolated microorganisms were S. aureus (38.7%), P. aeruginosa (37.4%) and Haemophilus spp (15.3%). A high resistance to erithromycine (35.0%) and clindamicine (29.4%) was observed in S. aureus strains and 25.9% of them were methicillin-resistant. P. aeruginosa strains were mainly gentamicin-resistant (31.0%). The rate of ampicillin-resistant Haemophilus spp. was 23.0% and it was due to the presence of beta-lactamases, but a high trimethoprim-sulfamethoxazole resistance was observed in this microorganism (59.0%).
Anzaudo
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Sección Bacteriología del Hospital de Niños Dr. Orlando Alassia Mendoza 4151, 3000, Santa Fe, Argentina. milanzaudo@yahoo.com.ar
Busquets
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NP
Ronchi
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Mayoral
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D001419:Bacteria / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000209:etiology / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D004198:Disease Susceptibility; D024881:Drug Resistance, Bacterial; D025141:Drug Resistance, Fungal; D005260:Female; D005658:Fungi / Q000187:drug effects / Q000302:isolation & purification; D006190:Haemophilus / Q000187:drug effects / Q000302:isolation & purification; D006192:Haemophilus Infections / Q000209:etiology / Q000382:microbiology; D006801:Humans; D007223:Infant; D008297:Male; D009181:Mycoses / Q000209:etiology / Q000382:microbiology; D011552:Pseudomonas Infections / Q000209:etiology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000209:etiology / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000209:etiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification