title: [Prediction of pelvic control using MRI for patients with cervical carcinoma treated with radiotherapy].
abstract: OBJECTIVE
  To investigate the usefulness of MRI for predicting pelvic control (PC) of cervical cancer treated with radiation therapy (RT).
  
  
  METHODS
  Forty-four cervical cancer patients treated with definitive RT were retrospectively analyzed. MRIs were completed before and after RT, and the longest diameter (LD) of the residual tumor was measured on post-RT MRI. Pathologic evaluation for residual tumor was also performed. Therapeutic response was assessed using MRI. Median follow-up time for the 44 patients was 34 months. The correlations between PC rate, MRI, and pathological findings were investigated.
  
  
  RESULTS
  The 3-year PC rates of LD = 0 cm (n = 23) after RT, 0 < LD <or= 2 cm (n = 15), and LD > 2 cm (n = 6) were 85%, 80%, and 0%, respectively (p < 0.0001). There was no significant difference in PC according to the presence (n = 8) or absence (n = 36) of residue in the pathologic materials (3-year PC rate: 63% vs. 77%). Three-year PC rates according to therapeutic responses were 85% in complete response (n = 23), 72% in partial response (n = 18), and 0% in stable disease or progressive disease (n = 3) (p < 0.0001).
  
  
  CONCLUSIONS
  MRI is useful for predicting PC in cervical cancer treated with RT, and LD greater than 2 cm after RT is a good marker for poor PC.
authors.affiliation: Department of Radiology, National Hospital Organization Shikoku Cancer Center.
authors.forename: Tomoko Hyodo
authors.initials: TH
authors.lastname: Kajiwara
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kataoka
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Hamamoto
authors.forename: Miho
authors.initials: M
authors.lastname: Ikura
authors.forename: Kouhei
authors.initials: K
authors.lastname: Hosokawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inoue
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mogami
authors.forename: Masamichi
authors.initials: M
authors.lastname: Hiura
authors.forename: Teruhito
authors.initials: T
authors.lastname: Mochizuki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010388:Pelvis / Q000473:pathology; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000532:radiotherapy*