title: Prevalence of measles antibody in children of different ages in Shiraz, Islamic Republic of Iran.
abstract: An outbreak of measles due to secondary vaccine failure prompted this investigation into the prevalence of measles antibody in children. We studied 608 children in 7 different age groups: 6, 9, 14 and 18 months and 6, 10 and 15 years. Children in the 2 youngest groups received no vaccination; the rest were vaccinated at 9 months and 15 months. The 15-year-old age group received an additional vaccination. Transplacental measles antibody (Ab) decreased from 10.0% at 6 months to 0% at 9 months. Measles Ab was positive in 52.9% (14 months), 89.4% (18 months), 60.8% 96 years), 45.0% (10 years) and 96.8% (15 years). To increase Ab levels, a booster vaccination is recommended, administered either with the second DPT booster or at pre-high school age.
authors.affiliation: Clinical Microbiology Research Centre, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: A
authors.initials: A
authors.lastname: Karimi
authors.forename: A
authors.initials: A
authors.lastname: Arjomandi
authors.forename: A
authors.initials: A
authors.lastname: Alborzi
authors.forename: M
authors.initials: M
authors.lastname: Rasouli
authors.forename: M R
authors.initials: MR
authors.lastname: Kadivar
authors.forename: B
authors.initials: B
authors.lastname: Obood
authors.forename: B
authors.initials: B
authors.lastname: Pourabbas
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control / Q000706:statistics & numerical data*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007117:Immunization, Secondary; D007074:Immunoglobulin G / Q000097:blood*; D015994:Incidence; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000706:statistics & numerical data; D007492:Iran / Q000453:epidemiology; D008297:Male; D008457:Measles / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission; D008459:Measles virus / Q000276:immunology*; D020380:Needs Assessment; D011159:Population Surveillance; D015995:Prevalence; D016036:Seroepidemiologic Studies; D012959:Socioeconomic Factors; D014504:Urban Health / Q000706:statistics & numerical data; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G