Antibacterial cleaning products and drug resistance.
We examined whether household use of antibacterial cleaning and hygiene products is an emerging risk factor for carriage of antimicrobial drug-resistant bacteria on hands of household members. Households (N = 224) were randomized to use of antibacterial or nonantibacterial cleaning and hygiene products for 1 year. Logistic regression was used to assess the influence of antibacterial product use in homes. Antibacterial product use did not lead to a significant increase in antimicrobial drug resistance after 1 year (odds ratio 1.33, 95% confidence interval 0.74-2.41), nor did it have an effect on bacterial susceptibility to triclosan. However, more extensive and longer term use of triclosan might provide a suitable environment for emergence of resistant species. Further research on this issue is needed.
Aiello
Allison E
AE
University of Michigan School of Public Health, Ann Arbor, Michigan 48104-2548, USA. aielloa@umich.edu
Marshall
Bonnie
B
Levy
Stuart B
SB
Della-Latta
Phyllis
P
Lin
Susan X
SX
Larson
Elaine
E
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005191:Family Characteristics; D006225:Hand / Q000382:microbiology; D006235:Hand Disinfection; D006795:Household Products / Q000009:adverse effects*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008826:Microbial Sensitivity Tests; D014260:Triclosan / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D014260:Triclosan