Influence of optic edge design, optic material, and haptic design on capsular bend configuration.
OBJECTIVE
To assess and classify capsular bend configuration at the optic rim and its association with posterior capsule (PCO) and anterior capsule opacification (ACO) and capsulorhexis contraction with various intraocular lenses (IOLs).


METHODS
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.


METHODS
A total of 659 post-cataract surgery eyes of 370 patients from different prospective randomized studies were evaluated. All eyes had standardized phacoemulsification surgery with implantation of an IOL in the capsular bag. The IOLs had a sharp or round optic edge design and were made of silicone, acrylic, or poly(methyl methacrylate) optic materials. One year postoperatively, the configuration of the capsular bend at the optic rim was assessed at the slitlamp, and standardized slitlamp images of ACO and fibrotic PCO were taken. One week, 1 year, and 3 years postoperatively, digital retroillumination images were taken for objective quantification of regeneratory PCO and the capsulorhexis area. The outcome measures were the type of capsular bend configuration, ACO score (0% to 100%), regeneratory PCO score (0 to 10), fibrotic PCO score (0 to 3), and amount of capsulorhexis contraction (mm(2)).


RESULTS
Four main types of capsular bend configuration were classified: parallel, "Y," right angle, and wrapping. The right-angle type was observed in the most cases (52%). Eyes with a wrapping capsular bend configuration had significantly less PCO, more capsulorhexis contraction, and more ACO than eyes with the other configurations. Wrapping capsule configuration was seen most often (55%) in round-edged silicone IOLs that had a thin optic rim.


CONCLUSIONS
The design and material of IOLs influenced the long-term capsular bend configuration at the optic rim. The right-angle type was the most common capsular bend configuration. Intraocular lenses with silicone optic material and a thin optic rim caused a wrapping capsule configuration and resulted in more capsulorhexis contraction and ACO, but less PCO.
Sacu
Stefan
S
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Findl
Oliver
O
Menapace
Rupert
R
Buehl
Wolf
W
D001672:Biocompatible Materials; D019923:Capsulorhexis; D002386:Cataract / Q000517:prevention & control; D004867:Equipment Design; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology* / Q000503:physiopathology*; D007910:Lenses, Intraocular; D055095:Optics and Photonics; D016032:Randomized Controlled Trials as Topic; D012828:Silicones
D001672:Biocompatible Materials; D012828:Silicones