[Advances of genome and secondary metabolism in Streptomyces].
Streptomycetes are Gram-positive, soil-inhabiting bacteria of Actinomycetales. These organisms exhibit complex life cycle and secondary metabolic pathways, and produce many economically important secondary metabolites. This review presented recent progress in Streptomycetes chromosome structure,genomics and the research of secondary metabolic pathway in Streptomyces. As more genomic sequences become available, it wiil be greatly facilitated to elucidate metabolic and regulatory networks and gain the over-production of desired metabolites or create the novel production of commercially important compounds.
Wu
Xue-Chang
XC
College of Life Sciences, Zhejiang University, Hangzhou 310012, China. mgf@zju.edu.cn
Miao
Ke-Pai
KP
Qian
Kai-Xian
KX
D016680:Genome, Bacterial; D023281:Genomics; D008660:Metabolism; D013302:Streptomyces / Q000737:chemistry / Q000235:genetics / Q000378:metabolism