Pure testicular carcinoid associated with intratubular germ cell neoplasia.
This case report describes for the first time a case of pure testicular carcinoid pre-aortic lymph node metastases in a 25 year old patient with carcinoid syndrome. The simultaneous occurrence of intratubular germ cell neoplasia in the surrounding testicular tissue was identified by OCT4 and placental-like alkaline phosphatase positivity. This confirmed that the tumour had a germ cell origin in the testis, rather than being a metastasis from an extragenital carcinoid.
Merino
J
J
Department of Pathology, University Hospital, E-18012 Granada, Spain.
Zuluaga
A
A
Gutierrez-Tejero
F
F
Del Mar Serrano
M
M
Ciani
S
S
Nogales
F F
FF
D000328:Adult; D002276:Carcinoid Tumor / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000473:pathology; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*