[Application of metal ions and their complexes in medicine II. Application of platina complexes in the treatment of tumor].
The rapid development of inorganic medical chemistry opens enormous potential for various applications of a range of inorganic substances in the medicine. Thus inorganic chemistry offers real possibilities to pharmaceutical industries, which used to be dominated by organic chemistry alone. The field has particularly been stimulated by the success-story of cisplatin, which is the World's best selling anticancer drug. Nowadays orally administered Pt(IV) complexes with reduced toxicity, and activity against resistant tumors are on various phases of clinical trial.
Nagy
László
L
Szegedi Tudományegyetem, Szervetlen és Analitikai Kémia Tanszék, Szeged.
Csintalan
Gabriella
G
Kálmán
Eszter
E
Nagy
Eniko
E
Sipos
Pál
P
D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D006801:Humans; D008670:Metals / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy*; D017671:Platinum Compounds / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D008670:Metals; D017671:Platinum Compounds; D002945:Cisplatin