Hypertension in sub-Saharan African populations.
BACKGROUND
Hypertension in sub-Saharan Africa is a widespread problem of immense economic importance because of its high prevalence in urban areas, its frequent underdiagnosis, and the severity of its complications.


RESULTS
We searched PubMed and relevant journals for words in the title of this article. Among the major problems in making headway toward better detection and treatment are the limited resources of many African countries. Relatively recent environmental changes seem to be adverse. Mass migration from rural to periurban and urban areas probably accounts, at least in part, for the high incidence of hypertension in urban black Africans. In the remaining semirural areas, inroads in lifestyle changes associated with "civilization" may explain the apparently rising prevalence of hypertension. Overall, significant segments of the African population are still afflicted by severe poverty, famine, and civil strife, making the overall prevalence of hypertension difficult to determine. Black South Africans have a stroke rate twice as high as that of whites. Two lifestyle changes that are feasible and should help to stem the epidemic of hypertension in Africa are a decreased salt intake and decreased obesity, especially in women.


CONCLUSIONS
Overall, differences from whites in etiology and therapeutic responses in sub-Saharan African populations are graded and overlapping rather than absolute. Further studies are needed on black Africans, who may (or may not) be genetically and environmentally different from black Americans and from each other in different parts of this vast continent.
Opie
Lionel H
LH
Hatter Institute for Cardiology Research, University of Cape Town, Cape Town, South Africa. Opie@capeheart.uct.ac.za
Seedat
Yackoob K
YK
D017954:Africa South of the Sahara / Q000453:epidemiology / Q000208:ethnology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000208:ethnology / Q000235:genetics; D039781:PubMed; D012084:Renin-Angiotensin System / Q000235:genetics; D012964:Sodium / Q000378:metabolism
D012964:Sodium