Blue rubber-bleb nevus syndrome: report of a case associated with osteoid osteomas.
Blue rubber-bleb nevus syndrome (BRBNS), or Bean's syndrome, is a rare angiomatosis characterized by multiple cavernous hemangiomas of the skin, mucosae and frequently of other sites. A 49-year-old male patient had been affected since birth by multiple angiomas localized in the skin, lips, oral cavity, cranial theca, and central nervous system; intrauterine rupture of angiomas in the right parietal lobe had caused partial hypotrophic paralysis of the left hemisoma. In addition to BRBNS, the patient was affected by three osteoid osteomas: this never-described clinical association is here discussed.
Palleschi
Giovanni Maria
GM
University of Florence, Department of Dermatological Sciences, Italy.
Torchia
Daniele
D
Fabbri
Paolo
P
D001859:Bone Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D018329:Nevus, Blue / Q000473:pathology*; D010017:Osteoma, Osteoid / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013577:Syndrome