title: Metallic stents for treatment of benign biliary obstruction: a long-term study comparing different stents.
abstract: OBJECTIVE
  To investigate the role of metallic stents in the treatment of benign biliary strictures and analyze the differences in primary patency associated with the various types of stents deployed.
  
  
  METHODS
  Between 1990 and 1997, 21 patients with benign obstructive jaundice were treated with transhepatic placement of metallic stents (11 Wallstents in 10 patients, nine Palmaz stents in seven patients, and four tantalum Strecker stents in four patients). Nineteen patients presented with strictures not responding to balloon angioplasty (postsurgical, n = 13; cholangitis, n = 5; unknown, n = 1). Estimates for cumulative patency, patency rate in the different stent groups, and survival were calculated with use of life-table analysis; the log-rank test was used to compare the different stent groups. The prognostic relevance of the selected variables-stent type, stent length, etiology, and location-were modeled with respect to patency according to Weibull distribution.
  
  
  RESULTS
  The median follow-up time was 80.5 months (range, 2-116 months). The median survival time was 91 months. One patient was lost to follow-up after 3 months. Repeat intervention for recurrent obstructive jaundice was necessary in 11 patients (55%), and the median patency rate was 26 months (range, 2-96 months). The Palmaz stent was the most effective in achieving long-term patency, with a median patency duration of 36 months (range, 22-96 months), versus 9 months (range, 3-67 months) for the Wallstent and 6 months (range, 2-15 months) for the tantalum Strecker stent. The cumulative patency rate with the Palmaz stent was significantly higher than for the tantalum Strecker stent (log-rank test, P = .017) and nonsignificantly higher compared with the Wallstent (log-rank test, P = .07). Multivariate analysis showed that the type of stent (Wald test, P = .003) and stent length (Wald test, P < .0001) influenced the patency rate.
  
  
  CONCLUSIONS
  These results suggest that the type of stent and the stent length have a significant influence on the patency rate. In this series, the Palmaz stent was most effective in achieving long-term patency in benign biliary strictures.
authors.affiliation: Department of Clinical Radiology, Universitätsklinikum, Mannheim, Germany. k.tesdal@klinikum-fn.de
authors.forename: I Kaare
authors.initials: IK
authors.lastname: Tesdal
authors.forename: Thomas
authors.initials: T
authors.lastname: Roeren
authors.forename: Christel
authors.initials: C
authors.lastname: Weiss
authors.forename: Werner
authors.initials: W
authors.lastname: Jaschke
authors.forename: Christoph
authors.initials: C
authors.lastname: Dueber
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D002779:Cholestasis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D041781:Jaundice, Obstructive / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000601:surgery; D011446:Prospective Studies; D011474:Prosthesis Design / Q000145:classification; D012086:Reoperation; D015607:Stents / Q000145:classification; D016019:Survival Analysis; D013995:Time; D016896:Treatment Outcome; D014654:Vascular Patency