Effects of Metals on 3-Acetyldeoxynivalenol Production by Fusarium graminearum R2118 in Submerged Cultures.
The effects of selected metals (Mg, Mn, Zn, and Fe) on 3-acetyldeoxynivalenol (3-ADN) production by Fusarium graminearum R2118 and on its mycelial growth were investigated by using a two-stage submerged-culture technique. In certain concentrations ranges, Mg and Fe stimulated growth but suppressed 3-ADN production; at other concentrations, Mg, Fe, and Zn suppressed growth but stimulated 3-ADN production. In contrast, Mn stimulated growth but totally inhibited 3-ADN production at all concentrations tested. In general, the production of 3-ADN was inversely related to the growth rate of the fungus with these metals. Mn appears to be a crucial factor regulating the onset of 3-ADN biosynthesis.
Vasavada
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Department of Environmental Toxicology, University of California, Davis, California 95616.
Hsieh
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