[Genetic variability and discriminating power of four microsatellite loci in Russian population].
Allele and genotype frequencies of 4 STR loci (LPL, vWA, FES/FPS H F 13B), used in forensic medicine, were analyzed in Russian Siberian population. Genetic and molecular diversity of these polymorphic systems were characterized in comparison with US Caucasoid population. High discriminating power (PD = 0.99975) of the system of four studied STR loci was shown. Comparative analysis of genetic diversity in Russian population and Caucasoid US population revealed the significant differences between two populations and demonstrated that STR frequency data for US population should not be used for forensic expertise in Russia. The data obtained in the current investigation may be used as reference data for forensic medicine laboratories in Siberia.
Shorokhova
D A
DA
Stepanov
B A
BA
Udovenko
Iu D
IuD
Novoselov
V P
VP
Pusyrev
V P
VP
D000483:Alleles; D016172:DNA Fingerprinting / Q000379:methods; D005006:Ethnicity; D005554:Forensic Medicine / Q000379:methods; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics*; D012800:Siberia