title: Novel Allylic Oxidation of alpha-Cedrene to sec-Cedrenol by a Rhodococcus Strain.
abstract: A bacterial strain, designated KSM-7358, that can use alpha-cedrene for growth was isolated. The strain was identified as a member of the genus Rhodococcus and catalyzed the novel allylic oxidation of alpha-cedrene regiospecifically to produce (R)-10-hydroxycedrene (sec-cedrenol) with a very high yield. alpha-Curcumene was also produced as a possible metabolite of sec-cedrenol. A possible pathway for the microbial conversion of alpha-cedrene to sec-cedrenol and alpha-curcumene is proposed.
authors.affiliation: Tochigi Research Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-34, and Wakayama Research Laboratories of Kao Corporation, 1334 Minato, Wakayama 640, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takigawa
authors.forename: H
authors.initials: H
authors.lastname: Kubota
authors.forename: H
authors.initials: H
authors.lastname: Sonohara
authors.forename: M
authors.initials: M
authors.lastname: Okuda
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Fujikura
authors.forename: S
authors.initials: S
authors.lastname: Ito