title: Incidence of intraocular pressure spike and other adverse events after vitreoretinal surgery.
abstract: OBJECTIVE
  To determine the incidence of significant postoperative intraocular pressure (IOP) elevation and other adverse medical events during the first postoperative day in patients undergoing inpatient vitreoretinal surgery.
  
  
  METHODS
  Noncomparative interventional case series.
  
  
  METHODS
  Two hundred two consecutive patients were admitted prospectively as inpatients after vitreoretinal surgery (vitrectomy and/or scleral buckling).
  
  
  METHODS
  Intraocular pressure was measured preoperatively, 5 to 12 hours postoperatively, and on postoperative day 1. Additionally, pain, nausea, and serious systemic adverse events were monitored.
  
  
  RESULTS
  Seventeen patients (8.4%) had a 5- to 12-hour IOP measurement above 29 mmHg. Thirty patients (14.8%) had a postoperative day 1 IOP measurement above 29 mmHg. Three patients (1.5%) required a parenteral narcotic to achieve adequate analgesia. Nine patients (4.5%) utilized a parenteral antiemetic for nausea control. Six patients (3.0%) had a hyperglycemic event. No serious systemic adverse events occurred in the early postoperative period.
  
  
  CONCLUSIONS
  The incidence of a significant IOP spike or systemic adverse events in the early postoperative period in patients undergoing vitreoretinal surgery is low.
authors.affiliation: Retina Service, Wills Eye Hospital, Philadelphia, Pennsylvania, USA. mailforanderson@yahoo.com
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Anderson
authors.forename: Mitchell S
authors.initials: MS
authors.lastname: Fineman
authors.forename: Gary C
authors.initials: GC
authors.lastname: Brown
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000601:surgery; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D008268:Macular Degeneration / Q000601:surgery; D008875:Middle Aged; D009325:Nausea / Q000188:drug therapy / Q000209:etiology*; D009798:Ocular Hypertension / Q000188:drug therapy / Q000209:etiology*; D010149:Postoperative Pain / Q000188:drug therapy / Q000209:etiology*; D011183:Postoperative Complications; D011446:Prospective Studies; D012163:Retinal Detachment / Q000601:surgery; D012167:Retinal Perforations / Q000601:surgery; D012591:Scleral Buckling / Q000009:adverse effects*; D014065:Tonometry, Ocular; D014821:Vitrectomy / Q000009:adverse effects*