Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.
BACKGROUND
Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins.


METHODS
We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.
Micheletti
Adilha Misson Rua
AM
Universidade Federal do Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
Silva
Ana Cristina Araújo Lemos da
AC
Nascimento
Antonio Geraldo
AG
Da Silva
Cléber Sérgio
CS
Murta
Eddie Fernando Candido
EF
Adad
Sheila Jorge
SJ
D018322:Angiofibroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001472:Bartholin's Glands; D003560:Cysts / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery