title: Interaction of polyelectrolytes and their composites with living cells.
abstract: Since the layer-wise polyelectrolyte deposition offers the opportunity to modify surfaces for biomedical applications, interactions and toxicity between polyelectrolytes and living cells become interesting. The aim of the present work is to determine the different factors such as contact area, charge, and transplantation site that influence the cell reaction to a specific polymer. We found that toxicity is influenced by all these factors and cannot be tested easily in a model.
authors.affiliation: CNR-INFM, Department of Physics, University of Genoa, 16146 Genoa, Italy.
authors.forename: Munish
authors.initials: M
authors.lastname: Chanana
authors.forename: Alessandra
authors.initials: A
authors.lastname: Gliozzi
authors.forename: Alberto
authors.initials: A
authors.lastname: Diaspro
authors.forename: Irina
authors.initials: I
authors.lastname: Chodnevskaja
authors.forename: Sabine
authors.initials: S
authors.lastname: Huewel
authors.forename: Vasiliy
authors.initials: V
authors.lastname: Moskalenko
authors.forename: Karin
authors.initials: K
authors.lastname: Ulrichs
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Galla
authors.forename: Silke
authors.initials: S
authors.lastname: Krol
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004573:Electrolytes / Q000009:adverse effects*; D042783:Endothelial Cells / Q000187:drug effects* / Q000473:pathology*; D007674:Kidney Diseases / Q000139:chemically induced* / Q000473:pathology*; D008422:Materials Testing; D049329:Nanostructures / Q000009:adverse effects* / Q000737:chemistry*; D051381:Rats; D011917:Rats, Inbred Lew; D013552:Swine
chemical_list: D004573:Electrolytes