title: Audit of intrapartum group B streptococcus prophylaxis.
abstract: Group B streptococcus is the most frequent cause of severe early onset neonatal infection. For over 3 years our department has employed a risk-factor-based protocol of intra-partum antibiotic prophylaxis. Prophylaxis has been considered adequate if women receive antibiotics more than 4 hours before delivery. This study aims (1) to establish the adequacy of intrapartum prophylaxis in routine clinical practice and (2) to determine whether changing the time interval (from commencement of prophylaxis to delivery) for adequacy from 4 to 2 hours (based on RCOG guidelines) improves the percentage of women receiving adequate prophylaxis. This was an audit against established protocol. Case notes of consecutive deliveries over a 4-week period were reviewed retrospectively. A total of 396 deliveries occurred during the study period. Some 44 women (11%) were eligible for antibiotic prophylaxis. Adequate prophylaxis was achieved in 21 cases (49%). If the time for prophylaxis to be considered adequate was reduced from 4 to 2 h, the number of women receiving adequate prophylaxis increased to 33 (76%). In conclusion, despite the protocol being well established, only half of the eligible women receive adequate intra-partum prophylaxis. Reducing the time interval from 4 to 2 h appreciably increases the number of women receiving adequate prophylaxis, which reduces the necessity of providing neonatal prophylaxis.
authors.affiliation: Department of Obstetrics, Princess Royal Maternity Hospital, Glasgow, UK. chitraven@yahoo.co.uk
authors.forename: C
authors.initials: C
authors.lastname: Rajagopalan
authors.forename: M
authors.initials: M
authors.lastname: Perry
authors.forename: P
authors.initials: P
authors.lastname: Owen
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D007743:Labor, Obstetric; D008485:Medical Audit; D010400:Penicillin G / Q000008:administration & dosage*; D011247:Pregnancy; D013290:Streptococcal Infections / Q000517:prevention & control*; D013292:Streptococcus agalactiae
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G