title: [Systemic lupus erythematosus presenting with a choreo-athetosic syndrome associated with antiphospholipid antibodies].
abstract: BACKGROUND
  Chorea is a rare manifestation of systemic lupus erythematosus (1-4 percent), commonly affecting young woman. Chorea is revealing lupic disease in 50 percent, in the other cases it occurs early in the course of the disease.
  
  
  METHODS
  A 33-year-old woman was hospitalized for choreo-athetosic movements prevailing on the left leg and arm accompanied by behavioral and general state deterioration. The biological assessment consolidated the diagnosis of lupic disease associated antiphospholipides antibody (aPL). Cerebral magnetic resonance imaging (MRI) was normal except for cortical and subcortical atrophy. The patient was treated by corticosteroids (1mg/kg/day) and then was lost to follow-up.
  
  
  CONCLUSIONS
  We review data in the literature on the pathophysiological mechanisms of lupic chorea focusing particularly on role of aPL.
authors.affiliation: Service de Neurologie et Explorations Fonctionnelles, CHU Ibn Rochd, Casablanca, Maroc. mo.mi2@caramail.com
authors.forename: M A
authors.initials: MA
authors.lastname: Rafai
authors.forename: B
authors.initials: B
authors.lastname: El Moutawakil
authors.forename: I
authors.initials: I
authors.lastname: Gam
authors.forename: K
authors.initials: K
authors.lastname: Hakim
authors.forename: H
authors.initials: H
authors.lastname: Fadel
authors.forename: N
authors.initials: N
authors.lastname: Kissani
authors.forename: I
authors.initials: I
authors.lastname: Slassi
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D002819:Chorea / Q000097:blood* / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood* / Q000150:complications* / Q000175:diagnosis
chemical_list: D017152:Antibodies, Antiphospholipid