Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols.
Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.
Black
Phillip J
PJ
Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Cami-Kobeci
Gerta
G
Edwards
Michael G
MG
Slatford
Paul A
PA
Whittlesey
Michael K
MK
Williams
Jonathan M J
JM