DRESS like severe drug rash with eosinophilia, atypic lymphocytosis and fever secondary to ceftriaxone.
We report a case in a 50-year-old male who had been treated with ceftriaxone for 3 weeks to treat meningitis. He was admitted 4 days after cessation of the ceftriaxone treatment with fever, headache, nausea, vomiting, myalgia, arthralgia, pruriginous skin rashes, and with edema on face. Blood tests showed marked eosinophilia and atypic lymphocytosis. He was successfully treated with prednisone p.o. We report this case as we could not recognize a case like this which was induced by ceftriaxone.
Akcam
Fusun Zeynep
FZ
Department of Clinical Microbiology and Infectious Disease, Suleyman Demirel University, Isparta, Turkey. fzeynep@med.sdu.edu.tr
Aygun
Fadime Ozge
FO
Akkaya
Vahide Baysal
VB
D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002443:Ceftriaxone / Q000009:adverse effects*; D003875:Drug Eruptions; D004342:Drug Hypersensitivity / Q000473:pathology; D004802:Eosinophilia / Q000139:chemically induced*; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008218:Lymphocytosis / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D002443:Ceftriaxone; D011241:Prednisone