title: [The correlation between prognostic factors and outcome of second look laparotomy in ovarian cancer].
abstract: OBJECTIVE
  The objective of this study was to verify the correlation between prognostic factors, positive or negative second look laparotomy (SLL) and 5-year survival in patients with ovarian cancer.
  
  
  METHODS
  Between 1984 and 1993, 178 patients after primary surgery and first-line chemotherapy with complete clinical response underwent second look laparotomy. The correlation between clinical stage and grade of cancers, residual disease, age of patients in two group of patients: with positive and negative second look laparotomy were evaluated.
  
  
  RESULTS
  95 patients (53%) had positive SLL. The 5-years survival in this group was only 20%. Adverse prognostic factors were: advanced primary stage (IV-0% of 5-years survival), low grade of differentiation (9.1% of 5-years survival) and residual disease > 2cm (9.4% of 5-years survival). The 5-year survival in group with negative SLL was 78.3%. The analysed prognostic factors in this group were insignificant in predicting 5-year survival.
  
  
  CONCLUSIONS
  This study confirms that the SLL can provide an important prognostic evaluation in patients without evidence of disease and allows surgical cytoreduction in group with positive SLL (more than 50% of patients). The analyzed prognostic factors in group with negative SLL were insignificant in predicting 5-year survival. The multicenter research for new prognostic factors in this group are required.
authors.affiliation: Klinika Ginekologii AM w Gdańsku.
authors.forename: Mirosław
authors.initials: M
authors.lastname: Dudziak
authors.forename: Dagmara
authors.initials: D
authors.lastname: Klasa-Mazurkiewicz
authors.forename: Tomasz
authors.initials: T
authors.lastname: Milczek
authors.forename: Ewa
authors.initials: E
authors.lastname: Zmudzińska
authors.forename: Janusz
authors.initials: J
authors.lastname: Emerich
mesh_terms: D005260:Female; D006801:Humans; D007813:Laparotomy / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery*; D011044:Poland; D011379:Prognosis; D024162:Second-Look Surgery; D016019:Survival Analysis; D013997:Time Factors