title: [High doses statins administration causing rhabdomyolysis: case report].
abstract: Rhabdomyolysis has been the theme in medical literature for the last fifty years. In these last decades, with statins being used in primary and secondary cardiovascular prevention events, this theme returns and statins are now pointed as the trigger to this almost always fatal complication. Rhabdomyolysis due to statins administration occurs mainly in association with other drugs. Our case reports on a patient with fatal statin-induced rhabdomyolysis whose medical history included diffuse atherosclerotic disease.
authors.affiliation: Departamento de Medicina Interna, Faculdade Evangélica do Paraná, Hospital Universitário Evangélico de Curitiba, Curitiba, RS. m.gama@sul.com.br
authors.forename: Mirnaluci P Ribeiro
authors.initials: MP
authors.lastname: Gama
authors.forename: Silviane
authors.initials: S
authors.lastname: Pellegrinello
authors.forename: Sheyla Santos Quelle
authors.initials: SS
authors.lastname: Alonso
authors.forename: Juliana Filus
authors.initials: JF
authors.lastname: Coelho
authors.forename: Caroline F Luz
authors.initials: CF
authors.lastname: Martins
authors.forename: Gleyne Lopes Kujew
authors.initials: GL
authors.lastname: Biagini
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D001161:Arteriosclerosis / Q000188:drug therapy; D004347:Drug Interactions; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D019821:Simvastatin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019821:Simvastatin