Advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in an "atheroma-free model": Down's syndrome.
Murdoch et al. in 1977 called Down syndrome an "atheroma-free model." In this preliminary study, we investigated advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy patients, we detected no new biochemical risk factors for atherosclerosis, such as AOPP and hs-CRP, so risks are probably considerably lower.
Goi
G
G
Baquero-Herrera
C
C
Licastro
F
F
Dogliotti
G
G
Corsi
M M
MM
D000293:Adolescent; D000328:Adult; D050197:Atherosclerosis / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000097:blood* / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010084:Oxidation-Reduction; D011506:Proteins / Q000378:metabolism*
D011506:Proteins; D002097:C-Reactive Protein