[Haemostatic ointment efficacy in the treatment and prevention of epistaxis: a multi-centric study in 100 patients].
OBJECTIVE
To evaluate the protective effects of an haemostatic ointment, at rhinosinusal mucosa level, on the development of bleeding in patients affected by epistaxis or with a positive clinical history for epistaxis in previous 7 days.


METHODS
100 patients affected by epistaxis or with a positive clinical history for epistaxis in previous 7 days. Patients underwent 15 days of treatment with an haemostatic ointment 2 times/day.


RESULTS
The haemostatic ointment significantly reduced the percentage of patients affected by epistaxis and the number and severity of bleeding episodes (p < 0.001). 51% of patients experienced nasal obstruction during treatment, which persisted at the end of therapy only in 11% of them (p < 0.001). Nasal burning, nasal itching and rinorrhea involved less than 40% of patients in the first days of treatment and no more than 10% at the end of therapy (p < 0.001).


CONCLUSIONS
The use of the haemostatic ointment in the treatment and in the prevention of not severe epistaxis acquire, in our opinion, a strong rationale.
Passàli
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Dipart. di Scienze Ortopedico Riabilitative, Radiologiche ed Otorinolaringoiatriche, Policlinico Le Scotte, Università di Siena, Italia. passali@unisi.it
D000328:Adult; D016009:Chi-Square Distribution; D004844:Epistaxis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D005260:Female; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D018579:Patient Selection; D012494:Sampling Studies; D013997:Time Factors; D016896:Treatment Outcome
D006490:Hemostatics; D009824:Ointments