title: Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation.
abstract: Von Hippel-Lindau disease (VHL) is a rare genetic disease with a lifetime risk of clear cell renal cell carcinoma in approximately 70% of cases. We present a case of a 63-year-old man with bilateral, multifocal renal masses. Genetic testing results were consistent with a VHL deletion. The patient had no other disease manifestations consistent with VHL. The patient underwent staged bilateral nephron-sparing procedures. Pathology of all renal masses revealed oncocytoma. To our knowledge, we describe the first reported case of multiple renal oncocytomas in a male patient with a germline VHL mutation.
authors.affiliation: Department of Urology, New York University School of Medicine/Bellevue Hospital, New York, New York, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Fiske
authors.forename: Rupa
authors.initials: R
authors.lastname: Patel
authors.forename: Eric
authors.initials: E
authors.lastname: Kau
authors.forename: John G
authors.initials: JG
authors.lastname: Pappas
authors.forename: Roberto A
authors.initials: RA
authors.lastname: Garcia
authors.forename: Samir S
authors.initials: SS
authors.lastname: Taneja
mesh_terms: D018249:Adenoma, Oxyphilic / Q000235:genetics*; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D006623:von Hippel-Lindau Disease / Q000235:genetics*