Novel derivatives of chitosan and their antifungal activities in vitro.
Three kinds of Schiff bases of carboxymethyl chitosan (CMCTS) were prepared, and their antifungal activities were assessed according to Jasso de Rodríguez's method. The results indicated that 2-(2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HNCMCTS) and 2-(5-chloro-2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HCCMCTS) had better inhibitory effects than those of chitosan or CMCTS against Fusarium oxysporium f. sp. vasinfectum, Alternaria solani, and Valsa mali.
Guo
Zhanyong
Z
Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China. guozhanyong@ms.qdio.ac.cn
Chen
Rong
R
Xing
Ronge
R
Liu
Song
S
Yu
Huahua
H
Wang
Pibo
P
Li
Cuiping
C
Li
Pengcheng
P
D000528:Alternaria / Q000187:drug effects / Q000254:growth & development; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D048271:Chitosan / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology*; D005670:Fusarium / Q000187:drug effects / Q000254:growth & development; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; D048271:Chitosan