[Peculiarities of pH influence on aldehyde reductase activity in the liver of rats from different age groups subject to immobilization stress].
In order to develop the notions about the causes of age-dependent changes in the organism resistance to the influence of damaging stress factors the study of aldehyde reductase activity manifestations was carried out in the liver of 1.5-, 2-, 6-, 12-, 24-months-old rats subject to immobilization stress with different values of pH of reactive mixture. It has been shown that the immobilization stress is accompanied by the shift of the enzyme pH-optimum to the acid side. This change manifestation in 1.5-months-old and 24-months-old animals has been less significant as compared with that in the rats of other age groups.
Fomina
E V
EV
Davydov
V V
VV
D000375:Aging / Q000378:metabolism*; D000449:Aldehyde Reductase / Q000378:metabolism*; D000818:Animals; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000201:enzymology* / Q000254:growth & development; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000201:enzymology*
D000449:Aldehyde Reductase