title: Impact of three-phase bone scintigraphy on the diagnosis and treatment of complex regional pain syndrome type I or reflex sympathetic dystrophy.
abstract: OBJECTIVE
  To determine the impact of three-phase bone scintigraphy (TPBS) on the diagnosis and management of complex regional pain syndrome type I (CRPSI) or reflex sympathetic dystrophy (RSD).
  
  
  METHODS
  Twenty consecutive patients with a recent clinical evidence of CRPSI were referred for TPBS as part of their routine management plan. All patients underwent neurological examinations with special attention to the evaluation of clinical features of vasomotor, sudomotor, motor and sensory dysfunction. Patients were followed prospectively. When both the clinical and TPBS results supported the diagnosis of CRPSI, patients were started on treatment.
  
  
  RESULTS
  Of the 20 patients, TPBS supported the diagnosis of RSD in 9 who were treated with steroids and physiotherapy. Complete follow-up was available for 7 of them and all had a satisfactory response to treatment. For the remaining 11 patients RSD was diagnosed clinically but not confirmed by TPBS. On follow-up there was no evidence that TPBS failed to identify RSD in these 11 patients.
  
  
  CONCLUSIONS
  The results indicate that TPBS confirmed the clinical diagnosis of RSD, and, more importantly, had a significant impact on its management.
authors.affiliation: Department of Medicine, Faculty of Medicine, Kuwait University. diaa@hsc.edu.kw
authors.forename: Dia
authors.initials: D
authors.lastname: Shehab
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Elgazzar
authors.forename: B David
authors.initials: BD
authors.lastname: Collier
authors.forename: Sleiman
authors.initials: S
authors.lastname: Naddaf
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Jarallah
authors.forename: Abdelmoneim
authors.initials: A
authors.lastname: Omar
authors.forename: Moudi
authors.initials: M
authors.lastname: Al-Mutairy
mesh_terms: D000328:Adult; D001847:Bone Diseases / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007730:Kuwait; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012019:Reflex Sympathetic Dystrophy / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000628:therapy
chemical_list: D019275:Radiopharmaceuticals