HIV vaccine design: insights from live attenuated SIV vaccines.
The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian immunodeficiency virus vaccines in monkeys. Here, the strategies defining key components of the protective immune response elicited by these vaccines are discussed.
Koff
Wayne C
WC
International AIDS Vaccine Initiative, New York, New York 10038, USA. wkoff@iavi.org
Johnson
Philip R
PR
Watkins
David I
DI
Burton
Dennis R
DR
Lifson
Jeffrey D
JD
Hasenkrug
Kim J
KJ
McDermott
Adrian B
AB
Schultz
Alan
A
Zamb
Timothy J
TJ
Boyle
Rosanne
R
Desrosiers
Ronald C
RC
D016915:AIDS Vaccines; D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D000818:Animals; D000882:Haplorhini; D006801:Humans; D016097:Simian Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D015302:Simian Immunodeficiency Virus / Q000276:immunology*; D014613:Vaccines, Attenuated
D016915:AIDS Vaccines; D014613:Vaccines, Attenuated