title: Combinatorial biomimetics. optimization of a composition of copper(II) poly-L-histidine complex as an electrocatalyst for O2 reduction by scanning electrochemical microscopy.
abstract: A simple approach to prepare and characterize biomaterial-based electrocatalysts for oxygen reduction was carried out. Poly-l-histidine was used as a matrix and ligand to complex Cu2+ to mimic the active sites of laccases. A modified glassy carbon (GC) electrode with Cu2+-poly-l-histidine complex decreases the oxygen reduction overpotential as compared with the bare GC electrode. An array of Cu2+-poly-l-histidine spots with different compositions was deposited on a GC substrate, and their catalytic activity for oxygen reduction was evaluated by a scanning electrochemical microscopy-based screening technique. The electrocatalytic activities of complexes for oxygen reduction strongly depended on the mole ratio of Cu2+ to poly-l-histidine and the applied potential of the substrate.
authors.affiliation: Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.
authors.forename: Yu Ching
authors.initials: YC
authors.lastname: Weng
authors.forename: Fu-Ren F
authors.initials: FR
authors.lastname: Fan
authors.forename: Allen J
authors.initials: AJ
authors.lastname: Bard
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D002384:Catalysis; D002413:Cations, Divalent; D003300:Copper / Q000737:chemistry*; D004563:Electrochemistry; D006639:Histidine / Q000737:chemistry*; D008667:Metalloproteins / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*
chemical_list: D002413:Cations, Divalent; D008667:Metalloproteins; C033223:polyhistidine; D006639:Histidine; D003300:Copper; D010100:Oxygen