Cardiomyopathy in Becker muscular dystrophy--does regional fibrosis mimic infarction?
We present a case of a 39-year-old man with Becker muscular dystrophy and severe congestive cardiac failure. Cardiac magnetic resonance imaging revealed subendocardial late gadolinium enhancement, similar to that seen in myocardial infarction. He had no risk factors for atherosclerotic coronary artery disease and coronary angiography was normal. We propose that regional subendocardial myocardial fibrosis which has been described histologically in the cardiomyopathy associated with Becker muscular dystrophy may resemble previous infarction at contrast enhanced cardiac magnetic resonance imaging.
Petrie
Colin J
CJ
Department of Cardiology, Western Infirmary, Glasgow, UK. colinjamespetrie@yahoo.co.uk
Mark
Patrick B
PB
Dargie
Henry J
HJ
D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D004719:Endomyocardial Fibrosis / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000150:complications* / Q000503:physiopathology; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology; D013318:Stroke Volume; D018754:Ventricular Dysfunction / Q000175:diagnosis / Q000209:etiology