title: [GHB, GBL and butanediol poisonings--a serious problem in Western Sweden].
abstract: Acute poisoning with GHB (Gamma-hydroxybutyrate, Gamma-hydroxybutyric acid) has been an increasing medical and social problem during the last decade in Sweden, especially on the west coast. The number of poisonings decreased in the beginning of this millennium but has again increased during the last years. At the same time the number of seizures by the police has increased similarly as well as the number of drug-related deaths. During 2004 the number of GHB-abuse related deaths in western Sweden was seven, approximately the same figures as for heroin. Two other substances which are transformed to GHB in the human body, GBL (gamma-butyrolactone) and 1,4-butanediol, have during the last years presented themselves among the same users as for GHB. Since GBL and butanediol are not classified as illicit drugs the possibilities for the police force to intervene and capture the drugs are severely restricted. Intoxication by GBL and butanediol has shown to be as dangerous as intoxication by GHB. Acute intoxications and abuse of these drugs is still a serious medical and social problem. A legal classification of GBL and butanediol as narcotics appears to be medically motivated.
authors.affiliation: Sahlgrenska Universitetssjukhuset/Sahlgrenska (SU/S), Göteborg. kai.knudsen@aniv.gu.se
authors.forename: Kai
authors.initials: K
authors.lastname: Knudsen
authors.forename: Joachim
authors.initials: J
authors.lastname: Greter
authors.forename: Mario
authors.initials: M
authors.lastname: Verdicchio
authors.forename: Thomas
authors.initials: T
authors.lastname: Cederquist
mesh_terms: D015107:4-Butyrolactone / Q000737:chemistry / Q000506:poisoning*; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002072:Butylene Glycols / Q000737:chemistry / Q000506:poisoning*; D062787:Drug Overdose; D004630:Emergencies; D006801:Humans; D006885:Hydroxybutyrates / Q000737:chemistry / Q000506:poisoning*; D019966:Substance-Related Disorders / Q000401:mortality; D013548:Sweden / Q000453:epidemiology
chemical_list: D002072:Butylene Glycols; D006885:Hydroxybutyrates; C111420:4-hydroxybutyric acid; D015107:4-Butyrolactone