Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen.
Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.
Klemm
Per
P
School of Molecular and Microbial Sciences, Building 76, University of Queensland, Brisbane QLD 4072, Australia.
Roos
Viktoria
V
Ulett
Glen C
GC
Svanborg
Catharina
C
Schembri
Mark A
MA
D000595:Amino Acid Sequence; D001437:Bacteriuria / Q000378:metabolism / Q000382:microbiology*; D004926:Escherichia coli / Q000235:genetics* / Q000472:pathogenicity* / Q000648:ultrastructure; D004927:Escherichia coli Infections / Q000378:metabolism / Q000382:microbiology*; D010861:Fimbriae, Bacterial / Q000235:genetics / Q000648:ultrastructure; D006801:Humans; D008969:Molecular Sequence Data