Axis formation: squint comes into focus.
Gene products provided by the mother to the embryo determine the body axes in most animals. A recent study in zebrafish proposes that the TGFss signal Squint is one such factor.
Schier
Alexander F
AF
Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA. schier@fas.harvard.edu
D000818:Animals; D001757:Blastomeres / Q000378:metabolism; D019521:Body Patterning / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology; D018507:Gene Expression Regulation, Developmental; D055456:Nodal Signaling Ligands; D023121:RNA, Messenger, Stored / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D015027:Zebrafish / Q000196:embryology*; D029961:Zebrafish Proteins / Q000378:metabolism* / Q000502:physiology
D055456:Nodal Signaling Ligands; D023121:RNA, Messenger, Stored; D029961:Zebrafish Proteins; C485171:ndr1 protein, zebrafish