title: [Idiopathic central precocious puberty in girls in Bahia, Brazil].
abstract: BACKGROUND
  Although the therapeutic effects of GnRH analogues (GnRHa) in central precocious puberty (CPP) have been established, clinical aspects may vary according to racial groups.
  
  
  OBJECTIVE
  To describe the profile of 175 girls from Bahia, Brazil, treated with GnRHa for idiopathic CPP.
  
  
  RESULTS
  The mulatto racial group predominated in the sample. The chronological age at puberty was 6.3 +/- 0.1 years. At diagnosis, height was 2.2 +/- 0.1 SD and body mass index (BMI) was 1.5 +/- 0.1 SD (> 2 SD in 32%), this one, inversely associated with age at onset of puberty (R = -0.20, p = 0.008). At treatment, chronological and bone ages were 8.4 +/- 0.1 years and 10.3 +/- 0.1 years, respectively. At the end of treatment (n = 52) age, BMI and height were 10.6 +/- 0.1 years, 1.6 +/- 0.2 SD and 1.9 +/- 0.2 SD, respectively.
  
  
  CONCLUSIONS
  Clinical presentation and evolution were similar to other studies, independently of racial characteristics. In this sample, treatment with GnRHa was not associated to significant weight gain.
authors.affiliation: Departamento de Pediatria, Faculdade de Medicina, Universidade Federal da Bahia, Centro de Diabetes e Endocrinologia, Salvador, BA.
authors.forename: Ana Luísa
authors.initials: AL
authors.lastname: Aguiar
authors.forename: Ana Cláudia
authors.initials: AC
authors.lastname: Couto-Silva
authors.forename: Isabel
authors.initials: I
authors.lastname: Freitas
authors.forename: Thomaz
authors.initials: T
authors.lastname: Cruz
authors.forename: Maíra
authors.initials: M
authors.lastname: Rodrigues
authors.forename: Luís Fernando
authors.initials: LF
authors.lastname: Adan
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002648:Child; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives*; D006801:Humans; D011629:Puberty, Precocious / Q000188:drug therapy* / Q000453:epidemiology; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D005300:Fertility Agents, Female; D007987:Gonadotropin-Releasing Hormone