title: Seroprevalence of HIV infection among blood donors in Port Harcourt, Nigeria.
abstract: BACKGROUND
  This study was undertaken to determine the seroprevalence of human immunodeficiency virus infection among blood donors living in the Niger Delta area of Nigeria.
  
  
  METHODS
  A total of 1500 consecutive donors comprising 1481 males and 19 females were screened for HIV-I and HIV-II antibodies using the World Health Organization (WHO) approved Immunocomb HIV I and II test kit. All initially reactive samples were confirmed using the Genscreen HIV I and II test kit.
  
  
  RESULTS
  The overall prevalence of HIV was 1.0%. The highest prevalence occurred in the 20 - 29 years age group (60%), followed by 30 - 39 years age group (21.5%). Commercial remunerated donors had the highest infection burden (1.4%) followed by the family replacement donors (0.7%) (p < 0.05). HIV-I accounted for the more predominant strain (0.8%).
  
  
  CONCLUSIONS
  This study has shown an overall prevalence of 1% among blood donors in the Niger Delta area of Nigeria with the highest prevalence amongst donors in the 20 to 29 years age group. We advocate for the mandatory screening of donor units intended for transfusion and the immediate take off of the national blood transfusion service. Furthermore, there is an urgent need for the health education of the people of the Niger Delta area on preventive measures aimed at arresting the spread of HIV.
authors.affiliation: Department of Haematology and Blood Transfusion, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
authors.forename: O A
authors.initials: OA
authors.lastname: Ejele
authors.forename: C A
authors.initials: CA
authors.lastname: Nwauche
authors.forename: O
authors.initials: O
authors.lastname: Erhabor
mesh_terms: D000328:Adult; D001782:Blood Donors; D016009:Chi-Square Distribution; D005260:Female; D015528:HIV Seroprevalence; D006801:Humans; D008297:Male; D009549:Nigeria / Q000453:epidemiology