title: [Cochlear involvement in acute otitis media].
abstract: OBJECTIVE
  An experimental design with mice has been realized to understand the origin of sensorial hearing loss related to infectious processes in the middle ear. Our aim is to study if the cilliated cells in the Corti organ's are lost after one or more acute otitis media.
  
  
  METHODS
  For that, thirty Sprague-Dawley mice have been divided in two groups. In the first one, we have induced one acute otitis media, in the second group we have induced two infections of this kind.
  
  
  RESULTS
  The statistic study shows that the loss of the cilliated cells is greater in the basal turn of the mice is cochlea, in the first group (alpha=0,020) and also in the second (alpha=0,038). We've noticed in the first group the near absence of injury in the middle turn, but in all samples of the second group we found that injury (alpha=0,002).
  
  
  CONCLUSIONS
  In acute otitis media, the loss of ciIliated cells are mainly in the basal turn of the mice is cochlea, and affects the middle turn when the infection is repeated.
authors.affiliation: Unidad de Otorrinolaringología Hospital Nostra Senyora de Meritxell Avinguda Fiter i Rossell, 1-13 Escaldes-Engordany. ebodet@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Bodet
authors.forename: V
authors.initials: V
authors.lastname: Martínez
authors.forename: C
authors.initials: C
authors.lastname: Romeu
mesh_terms: D000208:Acute Disease; D000818:Animals; D015834:Cochlear Diseases / Q000209:etiology*; D006198:Hair Cells, Auditory; D008297:Male; D010033:Otitis Media / Q000150:complications*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012008:Recurrence