[Symptoms of food-borne diseases and gastroenteritis in Kyushu, Japan].
In this study we analyzed the symptoms of gastroenteritis or food-borne disease caused by the 10 most prevalent pathogens: Norovirus, Salmonella, Vibrio parahaemolyticus, Campylobacter jejuni, Clostridium perfringens, Shiga toxin-producing Escherichia coli (STEC), enterotoxigenic E. coli (ETEC), Shigella sonnei/flexneri (Shigella), Staphylococcus aureus, and emetic-type Bacillus cereus. The symptoms diarrhea, vomiting, fever, abdominal pain, and headache, and the incubation period in 646 cases in 10 districts of Kyushu between January 2000 and December 2004 were recorded. The pathogen with the shortest mean incubation period was B. cereus (0.8 h), and was followed by S. aureus (3.3 h), C. perfringens (10.7 h) and V. parahaemolyticus (16.4 h). All the patients infected with B. cereus and S. aureus developed symptoms within 6 hours, and those infected with V. parahaemolyticus and C. perfringens developed symptoms within 24 hours. Bloody diarrhea was associated with STEC and Shigella, but rare with other pathogens. Vomiting was associated with almost all cases of S. aureus and B. cereus infection, and occurred in 71.5% of the Norovirus cases and 56.1% of the V. parahaemolyticus cases. Vomiting was less common in the C. perfringens (22.0%) and the ETEC and STEC (both about 5%). Bloody diarrhea, abdominal pain, and vomiting were statistically significantly more common with STEC 0157 infection than with STEC non-0157 infection. Since the cases analyzed in this study included all degrees of illness, mild to severe, and a wide range of ages, the information obtained will serve as a good reference material for administrative and laboratory work when an outbreak takes place.
Kudaka
Jun
J
Okinawa Prefectural Institute of Health and Environment.
Horikawa
Kazumi
K
Uryu
Kayo
K
Matsuyuki
Seiko
S
Ogata
Kikuyo
K
Kawano
Kimiko
K
Yamaguchi
Yoshitaka
Y
Yamasaki
Shogo
S
Watanabe
Haruo
H
Iwanaga
Masaaki
M
D015746:Abdominal Pain / Q000209:etiology*; D003967:Diarrhea / Q000821:virology; D004927:Escherichia coli Infections / Q000503:physiopathology; D005334:Fever / Q000209:etiology*; D005516:Food Microbiology; D005517:Foodborne Diseases / Q000382:microbiology / Q000503:physiopathology* / Q000821:virology; D005759:Gastroenteritis / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D029322:Norovirus / Q000472:pathogenicity; D013202:Staphylococcal Food Poisoning / Q000503:physiopathology; D014839:Vomiting / Q000209:etiology*