title: Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma.
abstract: This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined by quantifying the number of apoptotic bodies per hundred cells (apoptotic index) on haematoxylin and eosin stained histological sections [corrected] A significant correlation was noted between increasing apoptotic indices and increasing Gleason grades within a cancer.
authors.affiliation: Department of Pathology & General Surgery, J.N. Medical College, Aligarh Muslim University, Aligarh. ranasherwani@yahoo.com
authors.forename: Rana
authors.initials: R
authors.lastname: Sherwani
authors.forename: Sabina
authors.initials: S
authors.lastname: Khan
authors.forename: Nazoora
authors.initials: N
authors.lastname: Khan
authors.forename: Mohd
authors.initials: M
authors.lastname: Kamran
authors.forename: Musharraf
authors.initials: M
authors.lastname: Husain
mesh_terms: D000368:Aged; D017209:Apoptosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000473:pathology; D019048:Prostatic Intraepithelial Neoplasia / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*