Ulysses - an application for the projection of molecular interactions across species.
We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses.
Kemmer
Danielle
D
Center for Genomics and Bioinformatics, Karolinska Institutet, 171 77 Stockholm, Sweden. danielle@cmmt.ubc.ca
Huang
Yong
Y
Shah
Sohrab P
SP
Lim
Jonathan
J
Brumm
Jochen
J
Yuen
Macaire M S
MM
Ling
John
J
Xu
Tao
T
Wasserman
Wyeth W
WW
Ouellette
B F Francis
BF
D000818:Animals; D030541:Databases, Genetic; D006801:Humans; D023421:Models, Animal; D025941:Protein Interaction Mapping / Q000379:methods*; D012984:Software; D013045:Species Specificity; D014584:User-Computer Interface