title: Allosteric control of oligonucleotide hybridization by metal-induced cyclization.
abstract: A bis(terpyridine) modified single-stranded DNA smoothly forms a stable cycle by Fe2+-assisted ring closure. A novel, complex type of allosteric behavior is observed with Zn2+, which reversibly off-regulates binding of a complementary oligonucleotide only in a narrow concentration range.
authors.affiliation: Anorganisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
authors.forename: Mareike
authors.initials: M
authors.lastname: Göritz
authors.forename: Roland
authors.initials: R
authors.lastname: Krämer
mesh_terms: D001483:Base Sequence; D003500:Cyclization; D004270:DNA, Circular / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization / Q000379:methods*; D009841:Oligonucleotides / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D004270:DNA, Circular; D004277:DNA, Single-Stranded; D009841:Oligonucleotides; D015032:Zinc