title: [Assessment of thyroid function in women treated for vomiting in early pregnancy].
abstract: OBJECTIVE
  Hyperthyroidism does not influence procreation ability significantly, but very often causes complications of the course of pregnancy and increases neonatal morbidity and mortality in newborns. Nausea and vomiting in the first trimester of pregnancy are very common complaints in these patients.
  
  
  METHODS
  The aim of the study was to prove, that assessment of the thyroid hormones in every vomiting woman in the first trimester allows to start the proper treatment of hyperthyreosis as early as possible and improves the prognosis.
  
  
  METHODS
  Authors analyzed 22 pregnant women treated for vomiting during the first trimester in the Department of Obstetrics and 5 women treated in the Outpatient Clinic.
  
  
  RESULTS
  In none of them hormonal dysfunction was diagnosed before pregnancy. In 21 patients free thyroxine (fT4) in serum was assessed. In 8 cases (38%) hyperthyreosis was diagnosed. Except the routine anti vomiting treatment, they received a beta-blocker 30 mg per day. It allowed to avoid hospitalization in three pregnant women treated in the outpatient clinic. Two patients, who had earlier two spontaneous abortions, delivered healthy babies.
  
  
  CONCLUSIONS
  1. The beta-blocker in treatment gives very good results and allows to avoid hospitalization in patients with hyperthyroidism and hyper emesis gravidarum. 2. In some patients vomiting may be the only symptom of sub clinical hyperthyroidism in early pregnancy. Assessment of the thyroid hormones levels and adequate treatment may give these women a chance for a healthy child.
authors.affiliation: Klinika Połoznictwa Instytutu Połoznictwa i Chorób Kobiecych Akademii Medycznej w Gdańsku.
authors.forename: Beata
authors.initials: B
authors.lastname: Makowska
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Preis
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Swiatkowska-Freund
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Leszczyńska
mesh_terms: D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000097:blood / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control; D006980:Hyperthyroidism / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D012189:Retrospective Studies; D013974:Thyroxine / Q000097:blood*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D013974:Thyroxine