Comparison of albendazole regimen for prophylaxis of strongyloides hyperinfection in nephrotic syndrome patients on long-term steroids in Cambodia.
Nephrotic syndrome patients on long-term steroids face the risk of having heavy uncomplicated strongyloidiasis or death from its extreme form, the strongyloides hyperinfection. The risk can be minimized if we eradicate the parasite first. We compare a once daily and twice daily albendazole regimen in preventing this potentially fatal complication in 122 patients with nephrotic syndrome.
Leang
Bunse
B
Medical Department, Sihanouk Hospital Center of Hope (SHCH), Phnom Penh, Cambodia. tmed1shch@online.com.kh
Lynen
Lut
L
Schrooten
Ward
W
Hines
Jennifer
J
D000293:Adolescent; D000328:Adult; D015766:Albendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D002160:Cambodia; D018890:Chemoprevention; D006801:Humans; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage; D013256:Steroids / Q000008:administration & dosage; D017171:Strongyloides stercoralis / Q000187:drug effects* / Q000472:pathogenicity; D013322:Strongyloidiasis / Q000401:mortality / Q000517:prevention & control*; D016896:Treatment Outcome
D000871:Anthelmintics; D013256:Steroids; D011239:Prednisolone; D015766:Albendazole