title: Lymphangiogenesis in development and human disease.
abstract: The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues and returns it to the blood. Lymphatic vessels are also an essential part of the body's immune defence. They have an important role in the pathogenesis of several diseases, such as cancer, lymphoedema and various inflammatory conditions. Recent biological and technological developments in lymphatic vascular biology will lead to a better understanding and treatment of these diseases.
authors.affiliation: Molecular/Cancer Biology Laboratory, Ludwig Institute for Cancer, Research, P.O.B. 63 (Haartmaninkatu 8), 00014 University of Helsinki, Finland. Kari.Alitalo@Helsinki.FI
authors.forename: Kari
authors.initials: K
authors.lastname: Alitalo
authors.forename: Tuomas
authors.initials: T
authors.lastname: Tammela
authors.forename: Tatiana V
authors.initials: TV
authors.lastname: Petrova
mesh_terms: D000818:Animals; D004194:Disease; D042783:Endothelial Cells / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D042583:Lymphangiogenesis / Q000187:drug effects / Q000502:physiology*; D008207:Lymphatic Metastasis; D042601:Lymphatic Vessels / Q000166:cytology / Q000187:drug effects / Q000473:pathology / Q000502:physiology