title: Palladium-catalyzed asymmetric amination and imidation of 2,3-allenyl phosphates.
abstract: [reaction: see text] Asymmetric amination of 2,3-allenyl phosphates with nitrogen nucleophiles such as amines, hydroxylamines, and imides can be performed efficiently using a combination of zerovalent palladium complexes and SEGPHOS or MeOBIPHEP ligand, affording the corresponding optically active 1-aminated derivatives with enantiomeric excess of up to 97% ee.
authors.affiliation: Department of Chemistry, Graduate School of Engineering Science, Osaka University Machikaneyama, Toyonaka, Osaka 560-8531, Japan. imada@chem.es.osaka-u.ac.jp
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Imada
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nishida
authors.forename: Koji
authors.initials: K
authors.lastname: Kutsuwa
authors.forename: Shun-Ichi
authors.initials: S
authors.lastname: Murahashi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Naota