title: Hemolytic anemia produced by regurgitation through transposed chordae tendineae.
abstract: Hemolytic anemia after mitral repair and annuloplasty ring placement is very uncommon, and rarely described. The case is presented of a 53-year-old woman who developed severe mitral regurgitation and transfusion-dependent hemolytic anemia following mitral valve repair with a Carpentier-Edwards annuloplasty ring, which included transposition of chordae tendineae from the posterior leaflet to the anterior leaflet. Transesophageal echocardiography suggested that the transposed chordae tethered the anterior leaflet, causing malcoaptation of the leaflets. This resulted in central regurgitation divided by the chordae tendineae, producing two turbulent flow jets causing hemolysis. At reoperation, these chordae were removed and two longer Gortex neochordae to the anterior leaflet were placed with subsequent resolution of the anemia. To the authors' knowledge, this is the first case of hemolytic anemia caused by transposed mitral valve chordae tendineae from the posterior to the anterior leaflet.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, University of Kansas Hospital, Kansas City, Kansas 66160, USA.
authors.forename: James P
authors.initials: JP
authors.lastname: Birkbeck
authors.forename: Michael E
authors.initials: ME
authors.lastname: Gorton
authors.forename: James L
authors.initials: JL
authors.lastname: Vacek
mesh_terms: D000743:Anemia, Hemolytic / Q000209:etiology* / Q000628:therapy; D001803:Blood Transfusion; D002815:Chordae Tendineae / Q000601:surgery*; D017548:Echocardiography, Transesophageal; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery*; D012086:Reoperation