Movement disorders and Creutzfeldt-Jakob disease: a review.
Movement disorders are reported in a significant number of patients within the course of Creutzfeldt-Jakob disease (CJD). Although myoclonus is more frequent, dystonia, choreoathetosis, tremor, hemiballismus, and atypical parkinsonian syndromes have also been reported. In this review, we report the principal movement disorders associated with CJD and evaluate their correlations with neuroradiological and neuropathological findings that could in fact suggest a basal ganglia dysfunction. Further studies are warranted in order to clarify these correlations.
Maltête
David
D
Department of Neurology, Rouen University Hospital, Charles Nicolle, 1 Germont Street 76031 Rouen Cedex, France. david.maltete@chu-rouen.fr
Guyant-Maréchal
Lucie
L
Mihout
Bruno
B
Hannequin
Didier
D
D000818:Animals; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D004421:Dystonia / Q000503:physiopathology; D006801:Humans; D009069:Movement Disorders / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D009207:Myoclonus / Q000503:physiopathology; D010300:Parkinson Disease / Q000503:physiopathology; D011859:Radiography; D014202:Tremor / Q000503:physiopathology