title: Yeast polarity: negative feedback shifts the focus.
abstract: A new study of Cdc42p polarization in yeast suggests that the actin cytoskeleton can destabilize the polarity axis, causing Cdc42p foci to wander aimlessly around the cell cortex.
authors.affiliation: Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA. daniel.lew@duke.edu
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Lew
mesh_terms: D016764:Cell Polarity / Q000502:physiology*; D003599:Cytoskeleton / Q000502:physiology*; D008954:Models, Biological; D004718:Saccharomycetales / Q000166:cytology* / Q000502:physiology; D020846:cdc42 GTP-Binding Protein, Saccharomyces cerevisiae / Q000378:metabolism*
chemical_list: D020846:cdc42 GTP-Binding Protein, Saccharomyces cerevisiae