title: [Effective TS-1+paclitaxel administration for gastric cancer with malignant ascites--a case report].
abstract: We report a case in which TS-1 + paclitaxel (PTX) administration was effective for gastric cancer with malignant ascites. The patient was a 66-year-old male who received total gastrectomy, distal pancreatectomy and splenectomy. He complained of abdominal fullness and ascites 18 months later. The administered regimen of chemotherapy was TS-1 100 mg/day for two weeks, and PTX 120 mg/day on day 1 and 8 of TS-1 intake, followed by 1-week rest. Computed tomography (CT) showed complete loss of malignant ascites. The toxic events were grade 2 leukopenia and grade 2 alopecia.
authors.affiliation: Dept. of Gastroenterological Surgery, Shimonoseki Welfare Social Hospital.
authors.forename: Shigenori
authors.initials: S
authors.lastname: Sugihara
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ikuta
authors.forename: Hironori
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tsuruta
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yonemitsu
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Toyama
authors.forename: Kenichi
authors.initials: K
authors.lastname: Teshima
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001201:Ascites / Q000150:complications*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel; D002945:Cisplatin