Phage display systems and their applications.
Screening phage display libraries of proteins and peptides has, for almost two decades, proven to be a powerful technology for selecting polypeptides with desired biological and physicochemical properties from huge molecular libraries. The scope of phage display applications continues to expand. Recent applications and technical improvements driving further developments in the field of phage display are discussed.
Paschke
Matthias
M
Institut für Biochemie, Charité-Universitätsmedizin Berlin, Monbijoustrasse 2A, 10117 Berlin, Germany. matthias.paschke@charite.de
D001435:Bacteriophages / Q000235:genetics / Q000378:metabolism; D018076:DNA, Complementary / Q000235:genetics; D015723:Gene Library; D019151:Peptide Library; D011506:Proteins / Q000235:genetics* / Q000378:metabolism*
D018076:DNA, Complementary; D019151:Peptide Library; D011506:Proteins