title: Circadian pathway: the other shoe drops.
abstract: Three new papers report the long-awaited functional characterization of the Drosophila receptor for the circadian-rhythm-regulating signalling molecule PIGMENT DISPERSING FACTOR (PDF). The discovery of the PDF receptor heralds progress in understanding the circadian pacemaker circuit and output pathways in insects.
authors.affiliation: Department of Biology, New York University, New York 10003, USA.
authors.forename: Todd C
authors.initials: TC
authors.lastname: Holmes
authors.forename: Vasu
authors.initials: V
authors.lastname: Sheeba
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000235:genetics / Q000502:physiology; D002940:Circadian Rhythm / Q000235:genetics* / Q000502:physiology; D004330:Drosophila / Q000235:genetics* / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000235:genetics* / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled / Q000235:genetics* / Q000378:metabolism
chemical_list: D029721:Drosophila Proteins; D009479:Neuropeptides; C507073:PDFR protein, Drosophila; D043562:Receptors, G-Protein-Coupled; C113883:pdf protein, Drosophila