title: Severe pneumonia during primary infection with an atypical strain of Toxoplasma gondii in an immunocompetent young man.
abstract: We report a case of severe acute primary pulmonary toxoplasmosis in an immunocompetent young man living in Nice (Southern France). The Toxoplasma DNA extracted from the broncho-alveolar lavage fluid allowed a genetic characterization of the responsible strain which displayed an atypical genotype of Toxoplasma gondii. This unusual genetic composition of the parasite may have influenced, among other factors, the severity of the disease.
authors.affiliation: Centre Hospitalier-Universitaire de Nice, Service d'Infectiologie, Hôpital de l'Archet, BP 3079 06202--Nice Cedex 3, France. de-salvador.f@chu-nice.fr
authors.forename: Francine
authors.initials: F
authors.lastname: De Salvador-Guillouët
authors.forename: Daniel
authors.initials: D
authors.lastname: Ajzenberg
authors.forename: Sylvie
authors.initials: S
authors.lastname: Chaillou-Opitz
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Saint-Paul
authors.forename: Brigitte
authors.initials: B
authors.lastname: Dunais
authors.forename: Pierre
authors.initials: P
authors.lastname: Dellamonica
authors.forename: Pierre
authors.initials: P
authors.lastname: Marty
mesh_terms: D000328:Adult; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D014122:Toxoplasma / Q000145:classification*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000469:parasitology*
chemical_list: D000981:Antiprotozoal Agents