Regional brain cerebral glucose metabolism and temperament: a positron emission tomography study.
Personality, and in particular temperament, is thought to have a biological basis. In the present study, the relationships between regional brain glucose metabolism and temperament have been investigated. Regional brain glucose metabolism was measured using [18F] fluorodeoxyglucose positron emission tomography in 31 healthy subjects. Temperament was assessed using the Temperament and Character Inventory. Temperament dimensions were observed to be significantly correlated with specific brain regions. In particular, novelty seeking was significantly correlated with the superior temporal gyrus, inferior parietal lobule, and the precuneus, which have been reported to be related with impulsiveness, while reward dependence was significantly correlated with the caudate head, which has been shown to be associated with reward processing. The various aspects of temperament may have biological bases in the specific brain regions. The accumulation of results from studies of this kind should provide further evidence connecting personality traits with their biological bases.
Hakamata
Yuko
Y
Department of Psychology and Human Developmental Sciences, Nagoya University, Graduate School of Education and Human Development, Nagoya, Japan.
Iwase
Mikio
M
Iwata
Hiroshi
H
Kobayashi
Toshiki
T
Tamaki
Tsuneo
T
Nishio
Masami
M
Kawahara
Katsuhiko
K
Matsuda
Hiroshi
H
Ozaki
Norio
N
Honjo
Shuji
S
Inada
Toshiya
T
D000328:Adult; D000368:Aged; D016739:Behavior, Addictive / Q000378:metabolism / Q000503:physiopathology; D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000378:metabolism*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000378:metabolism; D004734:Energy Metabolism / Q000502:physiology*; D005106:Exploratory Behavior / Q000502:physiology; D005260:Female; D019788:Fluorodeoxyglucose F18; D007839:Functional Laterality / Q000502:physiology; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D007175:Impulsive Behavior / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009415:Nerve Net / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000378:metabolism; D009434:Neural Pathways / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000378:metabolism; D009483:Neuropsychological Tests; D009714:Nucleus Accumbens / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000378:metabolism; D049268:Positron-Emission Tomography; D012201:Reward; D013694:Temperament / Q000502:physiology*
D019788:Fluorodeoxyglucose F18; D005947:Glucose