Cell transplantation for patients with Parkinson's disease.
This chapter focuses on cell replacement therapies in Parkinson's disease (PD) and describes experimental data leading to clinical trials, as well as the methodology and efficacy of grafts of human embryonic nigral tissue in patients with PD. It also highlights some of the clinical problems the procedure presents and considers future alternative sources of donor tissue, including various forms of stem cells.
Paul
G
G
Neuronal Survival Unit, Experimental Medical Sciences, Wallenberg Neurocentrum, University of Lund, BMC A10, 22184 Lund, Sweden. gesine.paul@mphy.lu.se
D000818:Animals; D016380:Brain Tissue Transplantation; D018849:Controlled Clinical Trials as Topic; D004298:Dopamine / Q000378:metabolism; D006801:Humans; D010300:Parkinson Disease / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism
D004298:Dopamine