The analysis of contingency tables with ordinal data: an application to monitoring antibiotic resistance.
Rationalization of antibiotic therapy in the management of infectious diseases is helped by a knowledge of the patterns of sensitivity and resistance of bacteria to antibiotics and their possible changes both in time and from one hospital unit to another. In this paper we present the results regarding the sensitivities of several groups of bacteria and different Units of the S.Orsola-Malpighi Hospital of Bologna in the period 1995-1997. We apply recent methods of analysis of ordinal contingency tables that rely on stochastic ordering of the rows to test the assumption that a decrease (or increase) in sensitivity of bacteria to specific antibiotics has taken place against the alternative that no such thing has happened. In most cases the results seem to indicate an increase in sensitivity rather than what was expected, namely the opposite.
Bonetto
C
C
Dipartimento di Medicina e Salute Pubblica, Sezione di Psichiatria Ospedale Policlinico, Università di Verona P.le L.A. Scuro 10, 37134 Verona, Italy. chiara.bonetto.@univr.it
Giannerini
S
S
Giovagnoli
A
A
D004351:Drug Resistance; D007558:Italy; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data*; D015233:Models, Statistical; D016017:Odds Ratio; D013269:Stochastic Processes