title: Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients.
abstract: The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. sc4030@ha.mc.ntu.edu.tw
authors.forename: Shan-Chwen
authors.initials: SC
authors.lastname: Chang
authors.forename: Jann-Tay
authors.initials: JT
authors.lastname: Wang
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Huang
authors.forename: Yee-Chun
authors.initials: YC
authors.lastname: Chen
authors.forename: Chi-Tai
authors.initials: CT
authors.lastname: Fang
authors.forename: Wang-Huei
authors.initials: WH
authors.lastname: Sheng
authors.forename: Jiun-Ling
authors.initials: JL
authors.lastname: Wang
authors.forename: Chong-Jen
authors.initials: CJ
authors.lastname: Yu
authors.forename: Pan-Chyr
authors.initials: PC
authors.lastname: Yang
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood; D008137:Longitudinal Studies; D045473:Severe acute respiratory syndrome-related coronavirus / Q000276:immunology*; D045169:Severe Acute Respiratory Syndrome / Q000821:virology*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M