title: Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli.
abstract: A new norditerpenoid and a known alkaloid were isolated from the alkaloidal fraction of the processed tubers of Aconitum carmichaeli. The structure of the new norditerpenoid alkaloid was elucidated as lipoforesaconitine (1) on the basis of spectroscopic analysis. The known norditerpenoid alkaloid was characterized as lipoyunanaconitine (2). In addition, a new flavonoid, 6"-O-acetylliquiritin (7), along with a known ceramide, (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxylignoceroylamino]-8(E)-octadecene-1,3,4-triol (3), as well as a known steroid saponin, gracillin (8), and three known flavonoids, liquiritigenin (4), isoliquiritigenin (5), and liquiritin (6), were also isolated and characterized. All known compounds were isolated from this plant for the first time. The structures of the isolates were established by spectroscopic and chemical methods.
authors.affiliation: Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
authors.forename: Sang Hee
authors.initials: SH
authors.lastname: Shim
authors.forename: So Young
authors.initials: SY
authors.lastname: Lee
authors.forename: Ju Sun
authors.initials: JS
authors.lastname: Kim
authors.forename: Kun Ho
authors.initials: KH
authors.lastname: Son
authors.forename: Sam Sik
authors.initials: SS
authors.lastname: Kang
mesh_terms: D000107:Acetylation; D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D002240:Carbohydrate Sequence; D002681:China; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry; D013055:Spectrophotometry, Infrared
chemical_list: D000470:Alkaloids; D004224:Diterpenes