title: In situ dye injection bile leakage test of the graft in living donor liver transplantation.
abstract: BACKGROUND
  Bile leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ leakage testing of the cut surface of grafts in LDLT.
  
  
  METHODS
  A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of bile leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables.
  
  
  RESULTS
  Bile leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of bile leakage (22.5%). On the other hand, there was only one case (2.5%) of bile leakage in the test group (P<0.05). The bile leakage case in the test group was resolved preservationally. However, 2 of the 9 (22.2%) bile leakage cases in the control group required surgery.
  
  
  CONCLUSIONS
  Although there is biliary complication, especially bile leakage from the cut surface, as an inevitable consequence of LDLT, this study suggests that there is advantage in conducting bile leakage testing to minimize the incidence of bile leakage from the cut surface, which is associated with a high risk of graft failure.
authors.affiliation: Department of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi, Japan. tsuehiro@med.gunma-u.ac.jp
authors.forename: Taketoshi
authors.initials: T
authors.lastname: Suehiro
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shimada
authors.forename: Keiji
authors.initials: K
authors.lastname: Kishikawa
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Shimura
authors.forename: Yuji
authors.initials: Y
authors.lastname: Soejima
authors.forename: Tomoharu
authors.initials: T
authors.lastname: Yoshizumi
authors.forename: Kohji
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Mochida
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Maehara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D000328:Adult; D001652:Bile Ducts / Q000601:surgery; D002648:Child; D005260:Female; D005705:Gallbladder Diseases / Q000209:etiology / Q000601:surgery; D006801:Humans; D007208:Indocyanine Green; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D019520:Living Donors; D008297:Male
chemical_list: D007208:Indocyanine Green