title: [Viral diseases as a predisposing factor of developing secondary oto- and rhinogenic bacterial meningitis].
abstract: Effects of viruses and bacterial associations are suggested to promote secondary purulent intracranial complications in ENT patients. Fundamental aspects of pathogenesis of viral neuroinfections and pathogenetic mechanisms of different conditions provoked by viral factors promoting bacterial complications are presented. Hemoculture, and cerebrospinal fluid in 24 patients with secondary purulent rhinogenic and otogenic meningitis were studied with polymerase chain reaction for enteroviruses, cytomegaloviruses, Epstein-Barr, herpes, zoster viruses. The viruses were present in the studied media in 29.4% samples.
authors.forename: V F
authors.initials: VF
authors.lastname: Antoniv
authors.forename: N A
authors.initials: NA
authors.lastname: Mal'ginova
authors.forename: E V
authors.initials: EV
authors.lastname: Kovalenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Lebedeva
mesh_terms: D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis; D004770:Enterovirus / Q000235:genetics / Q000302:isolation & purification; D004769:Enterovirus Infections / Q000150:complications* / Q000821:virology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000209:etiology*; D008875:Middle Aged; D010031:Otitis / Q000150:complications* / Q000821:virology; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D012220:Rhinitis / Q000150:complications* / Q000821:virology; D012307:Risk Factors
chemical_list: D004279:DNA, Viral