Inhibition of NFAT increases osteoblast differentiation by increasing Fra-2 expression.
Zayzafoon
M
M
Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA. mzayzafo@path.uab.edu
D000818:Animals; D015153:Blotting, Western; D002454:Cell Differentiation / Q000502:physiology; D002460:Cell Line; D016572:Cyclosporine / Q000494:pharmacology; D024202:Electrophoretic Mobility Shift Assay; D051921:Fos-Related Antigen-2 / Q000235:genetics*; D007166:Immunosuppressive Agents / Q000494:pharmacology; D051379:Mice; D050778:NFATC Transcription Factors / Q000037:antagonists & inhibitors* / Q000235:genetics; D010006:Osteoblasts / Q000502:physiology*; D034741:RNA, Small Interfering / Q000494:pharmacology; D020133:Reverse Transcriptase Polymerase Chain Reaction
D051921:Fos-Related Antigen-2; D007166:Immunosuppressive Agents; D050778:NFATC Transcription Factors; D034741:RNA, Small Interfering; D016572:Cyclosporine