Early development of neurophysiological processes involved in normal reading and reading disability: a magnetic source imaging study.
This longitudinal study examined the development of the brain mechanism involved in phonological decoding in beginning readers using magnetic source imaging. Kindergarten students were assigned to 2 groups: those who showed mastery of skills that are important predictors of proficient reading (low-risk group) and those who initially did not show mastery but later benefited from systematic reading instruction and developed average-range reading skills at the end of Grade 1 (high-risk responders). Spatiotemporal profiles of brain activity were obtained during performance of letter-sound and pseudoword naming tasks before and after Grade 1 instruction. With few exceptions, low-risk children showed early development of brain activation profiles that are typical of older skilled readers. Provided that temporoparietal and visual association areas were recruited into the brain mechanism that supported reading, the majority of high-risk responder children benefited from systematic reading instruction and developed adequate reading abilities.
Simos
Panagiotis G
PG
Department of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX, USA. psimos@psy.soc.uoc.gr
Fletcher
Jack M
JM
Sarkari
Shirin
S
Billingsley
Rebecca L
RL
Francis
David J
DJ
Castillo
Eduardo M
EM
Pataraia
Ekaterina
E
Denton
Carolyn
C
Papanicolaou
Andrew C
AC
D000704:Analysis of Variance; D001921:Brain / Q000033:anatomy & histology / Q000503:physiopathology; D001931:Brain Mapping; D002648:Child; D004410:Dyslexia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007804:Language Development; D008137:Longitudinal Studies; D015225:Magnetoencephalography; D008297:Male; D010153:Paired-Associate Learning / Q000502:physiology; D011932:Reading; D012306:Risk; D014706:Verbal Learning / Q000502:physiology*