title: Intrathecal and epidural anesthesia and analgesia for cardiac surgery.
abstract: Adequate postoperative analgesia prevents unnecessary patient discomfort. It may also decrease morbidity, postoperative hospital length of stay and, thus, cost. Achieving optimal pain relief after cardiac surgery is often difficult. Many techniques are available, and all have specific advantages and disadvantages. Intrathecal and epidural techniques clearly produce reliable analgesia in patients undergoing cardiac surgery. Additional potential benefits include stress response attenuation and thoracic cardiac sympathectomy. The quality of analgesia obtained with thoracic epidural anesthetic techniques is sufficient to allow cardiac surgery to be performed in awake patients without general endotracheal anesthesia. However, applying regional anesthetic techniques to patients undergoing cardiac surgery is not without risk. Side effects of local anesthetics (hypotension) and opioids (pruritus, nausea/vomiting, urinary retention, and respiratory depression), when used in this manner, may complicate perioperative management. Increased risk of hematoma formation in this scenario has generated much of lively debate regarding the acceptable risk-benefit ratio of applying regional anesthetic techniques to patients undergoing cardiac surgery.
authors.affiliation: Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois 60637, USA. mchaney@dacc.uchicago.edu
authors.forename: Mark A
authors.initials: MA
authors.lastname: Chaney
mesh_terms: D015360:Analgesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000770:Anesthesia, Endotracheal / Q000009:adverse effects / Q000379:methods*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy / Q000453:epidemiology; D019106:Postoperative Hemorrhage / Q000139:chemically induced* / Q000453:epidemiology*; D016032:Randomized Controlled Trials as Topic