Development of severe ovarian hyperstimulation syndrome after inadvertent stimulation with a gonadotropin-releasing hormone agonist and human menopausal gonadotropin in a pre-existing early pregnancy.
OBJECTIVE
To report a case of severe ovarian hyperstimulation syndrome (OHSS) after inadvertent GnRH long protocol/hMG stimulation in a pre-existing early pregnancy.


METHODS
Case report.


METHODS
Private infertility clinic.


METHODS
A 28-year-old woman who conceived spontaneously following IVF and cryo-embryo transfer (cryo-ET).


METHODS
IVF/intracytoplasmic sperm injection (ICSI), cryo-ET, analgesia, and forced diuresis.


METHODS
Viable pregnancy.


RESULTS
Viable pregnancy with OHSS despite inadvertent administration of GnRH-agonist, stimulation with hMG, and ET in a pre-existing pregnancy.


CONCLUSIONS
Observation of follicle development following stimulation during pregnancy with low quantity and poor quality oocytes combined with abnormal endometrium.
Zech
Nicolas H
NH
Institute for Reproductive Medicine and Endocrinology, Bregenz, Austria. zech@ivf.at
Netzbandt
Paulo
P
Zech
Herbert
H
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006062:Gonadotropins / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D008593:Menopause; D016471:Ovarian Hyperstimulation Syndrome / Q000139:chemically induced* / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First
D006062:Gonadotropins; D007987:Gonadotropin-Releasing Hormone