title: Swine in biomedical research: creating the building blocks of animal models.
abstract: The opportunities for utilizing swine biomedical models are immense, particularly in models that address lifestyle issues (nutrition, stress, alcohol, drugs of abuse, etc.). However, in order to fully capitalize upon the promise, there needs to be a more general recognition of these cofactors, such as nutrition, as key modulators of phenotype via genomic, epigenetic, and postgenomic mechanisms. Furthermore, increased interactions between nutrition scientists and clinical and fundamental researchers in other disciplines, including developmental biology, immunology, neuroscience, oncology, and cardiovascular and gastrointestinal physiology, are required. Closing discussions focused on the need for future conferences at more frequent intervals to support interactions between the various disciplines. This was especially critical because of the global distribution of investigators.
authors.affiliation: University of Illinois, Institute for Genomic Biology, 382 ERML, 1201 W. Gregory Avenue, Urbana, IL 61801, USA. schook@uiuc.edu
authors.forename: Lawrence
authors.initials: L
authors.lastname: Schook
authors.forename: Craig
authors.initials: C
authors.lastname: Beattie
authors.forename: Jonathan
authors.initials: J
authors.lastname: Beever
authors.forename: Sharon
authors.initials: S
authors.lastname: Donovan
authors.forename: Russell
authors.initials: R
authors.lastname: Jamison
authors.forename: Federico
authors.initials: F
authors.lastname: Zuckermann
authors.forename: Steven
authors.initials: S
authors.lastname: Niemi
authors.forename: Max
authors.initials: M
authors.lastname: Rothschild
authors.forename: Mark
authors.initials: M
authors.lastname: Rutherford
authors.forename: Douglas
authors.initials: D
authors.lastname: Smith
mesh_terms: D000818:Animals; D035843:Biomedical Research; D004195:Disease Models, Animal; D006801:Humans; D023421:Models, Animal; D013552:Swine