title: Ethanol Perturbs Glycosylation and Inhibits Hypersecretion in Trichoderma reesei.
abstract: The effects of ethanol and phenylethanol on the growth of and glycoprotein secretion by Trichoderma reesei were studied. Low levels (1.5%, vol/vol) of ethanol perturbed the glycosylation process, as shown by alterations in the isoelectric profile of the secreted proteins and a reduction in the rate of incorporation of mannose into oligosaccharides. In addition to these effects on posttranslational modification, ethanol drastically lowered the protein secretion level of a hypersecretory strain.
authors.affiliation: Department of Biology, Lehigh University, Bethlehem, Pennsylvania 18015.
authors.forename: H
authors.initials: H
authors.lastname: Merivuori
authors.forename: B S
authors.initials: BS
authors.lastname: Montenecourt
authors.forename: J A
authors.initials: JA
authors.lastname: Sands