title: The Surviving Sepsis Campaign sepsis change bundles and clinical practice.
abstract: The Surviving Sepsis Campaign (SSC) is an international effort to reduce mortality in severe sepsis and septic shock. The campaign included the creation of evidence-based guidelines sponsored and endorsed by 11 international organizations. From these guidelines, sepsis change bundles for initial resuscitation (6 hours) and management (24 hours) were created as a performance improvement tool. In this issue of Critical Care, Gao et al. have evaluated performance at their institution by using a close adaptation of the two SSC bundle sets and demonstrated an association between 100% compliance with the bundle elements and clinical outcome. The next step will be to demonstrate that the use of education and feedback for performance improvement will increase compliance and decrease mortality in the patient population in general.
authors.affiliation: Section of Critical Care Medicine, Cooper University Hospital, Robert Wood Johnson Medical School, Camden, New Jersey, USA. dellinger-phil@cooperhealth.edu
authors.forename: R Phillip
authors.initials: RP
authors.lastname: Dellinger
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Vincent
mesh_terms: D002985:Clinical Protocols; D003422:Critical Care / Q000592:standards*; D004739:England / Q000453:epidemiology; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D017052:Hospital Mortality; D006801:Humans; D010043:Outcome and Process Assessment, Health Care / Q000379:methods; D018805:Sepsis / Q000401:mortality* / Q000628:therapy*; D016019:Survival Analysis