[Cerebral aneurysm related to pediatric AIDS. Case report].
BACKGROUND
Aneurysms, described in pediatric AIDS, are related with bad prognosis with high mortality in 5 months. The twenty reports found in literature were considered late (mean age 9.97 years old) and associated with severe immunological involvement. The mean CD-4 count was 79.17 cells and mean viral load 222,662 copies/mL. Some authors consider this complication associated to the human immunodeficiency virus (HIV), to an opportunistic agent (citomegalovirus and Mycobacterium avium) or due to inflammatory mechanisms related with the immunological improvement.


METHODS
This paper present a 9 years old girl with severe AIDS (C-3) and with transient amaurosis related to transient ischemic attacks on ophthalmic artery during her immunological improvement on viral load and CD-4 counts. Necropsy showed aneurysm due to atypical micobateriosis.


CONCLUSIONS
This report highlights the occurrence of this rare but severe HIV complication witch was associated with an opportunistic etiology during an immunological recovery, when inflammatory mediators could play a role.
Fernandes
A R
AR
Servicio de Neurología Pediátrica, Hospital Municipal Jesus, Río de Janeiro, Brazil. xande.fernandes@globo.com
Favoreto
A
A
Cruz
A
A
Aloe
M
M
Penna
C
C
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology / Q000503:physiopathology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000503:physiopathology; D018791:CD4 Lymphocyte Count; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D015269:Mycobacterium avium Complex; D019562:Viral Load