title: Kinetic and safety assessment for salicylic acid nitration by nitric acid/acetic acid system.
abstract: The nitration process of salicylic acid for the production of the important intermediate 5-nitrosalicylic acid is studied from thermokinetic and safety points of view. Investigations carried out by considering, as process deviations, the loss of the thermal control point out the possibility of runaway phenomena due to the occurrence of polynitration reactions. Isothermal experiments are carried out in various conditions to assess the involved reaction network and reaction kinetics.
authors.affiliation: Università di Napoli Federico II, p.le V. Tecchio, 80-80125 Napoli, Italy. roberto.andreozzi@unina.it
authors.forename: R
authors.initials: R
authors.lastname: Andreozzi
authors.forename: V
authors.initials: V
authors.lastname: Caprio
authors.forename: I
authors.initials: I
authors.lastname: Di Somma
authors.forename: R
authors.initials: R
authors.lastname: Sanchirico
mesh_terms: D019342:Acetic Acid / Q000737:chemistry*; D007700:Kinetics; D009566:Nitrates / Q000737:chemistry*; D017942:Nitric Acid / Q000737:chemistry*; D009596:Nitrophenols / Q000737:chemistry; D012449:Safety; D020156:Salicylic Acid / Q000737:chemistry*; D013696:Temperature
chemical_list: D009566:Nitrates; D009596:Nitrophenols; D017942:Nitric Acid; C045573:2-nitrophenol; D020156:Salicylic Acid; D019342:Acetic Acid