title: 'Computational evolution' offers riboswitch solution.
abstract: A computational strategy for the fast and efficient design of sensitive, sequence-activated ribozymes could dramatically reduce the time and benchwork investment for scientists interested in engineering specialized RNA-based tools.
authors.forename: Michael
authors.initials: M
authors.lastname: Eisenstein
mesh_terms: D000818:Animals; D019295:Computational Biology; D019143:Evolution, Molecular; D005818:Genetic Engineering; D006801:Humans; D012313:RNA / Q000737:chemistry*; D016337:RNA, Catalytic / Q000737:chemistry*
chemical_list: D016337:RNA, Catalytic; D012313:RNA