title: [Dermatofibrosarcoma protuberans. About 18 cases].
abstract: Dermatofibrosarcoma protuberans (DFSP) is a rare mesenchyma skin tumor. It is characterized by a slow growth with a high rate of recurrence but limited potential for metastasis. We report the result of a retrospective study of 18 cases of DFSP collected over 16 years in the dermatology department of La Rabta Hospital. The mean age was 32 years with a sex ratio of 1.57. The site of predilection was the trunk (77.5%). Histological features were typical in all cases with positivity for CD34 in 14 cases. Treatment was surgical in 13 cases. DFSP is a tumor of intermediate malignancy, which can have aggressive course. This tumor is best treated with surgery in which large excision are necessary to reduce the risk of recurrence.
authors.affiliation: Service de dermatologie, Hôpital La Rabta, Tunis.
authors.forename: I
authors.initials: I
authors.lastname: Zaraa
authors.forename: E
authors.initials: E
authors.lastname: Cherif
authors.forename: L
authors.initials: L
authors.lastname: Ferchichi
authors.forename: K
authors.initials: K
authors.lastname: Ben Romdhane
authors.forename: N
authors.initials: N
authors.lastname: Kchir
authors.forename: M
authors.initials: M
authors.lastname: Mokni
authors.forename: A Ben Osman
authors.initials: AB
authors.lastname: Dhahri
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D018223:Dermatofibrosarcoma / Q000473:pathology* / Q000601:surgery*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012744:Sex Ratio