title: Top-down versus step-up approaches to chronic inflammatory bowel disease: presumed innocent or presumed guilty.
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Hanauer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001691:Biological Therapy; D003424:Crohn Disease / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D018579:Patient Selection; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000305:Adrenal Cortex Hormones; D014409:Tumor Necrosis Factor-alpha