Sphingolactones: selective and irreversible inhibitors of neutral sphingomyelinase.
Wascholowski
Veit
V
University of Leipzig, Institute of Organic Chemistry, 04103 Leipzig, Germany.
Giannis
Athanassios
A
D002518:Ceramides / Q000138:chemical synthesis / Q000737:chemistry; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008968:Molecular Conformation; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors*; D013109:Sphingomyelins / Q000737:chemistry; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors
D002518:Ceramides; D004791:Enzyme Inhibitors; D007783:Lactones; D013109:Sphingomyelins; D013108:Sphingomyelin Phosphodiesterase