Takayasu's arteritis and ulcerative colitis in a young non-Asian woman: a rare association.
The association between ulcerative colitis and Takayasu's arteritis has been well described in patients of Asian ethnicity. We present the third non-Asian case reported in the English literature, of a 37-year-old woman with a 4-year history of Takayasu's arteritis, who developed idiopathic ulcerative colitis. She was found to carry the human leucocyte antigens HLA-B52 and DR2, which have been previously noted to be associated with these inflammatory conditions, mainly in the Japanese population. Ulcerative colitis was steroid-dependent despite simultaneous administration of mesalazine. Azathioprime achieved remission of both diseases. The possible pathogenic association of the disorders is discussed.
Katsinelos
P
P
Department of Endoscopy and Motility Unit, Central Hospital, Thessaloniki, Greece. papaziog@med.auth.gr
Tsolkas
P
P
Beltsis
A
A
Chatzimavroudis
G
G
Papaziogas
B
B
Kapelidis
P
P
Katsinelos
T
T
Atmatzidis
K
K
Paroutoglou
G
G
D000328:Adult; D044466:Asian People; D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D035583:Rare Diseases; D013223:Statistics as Topic; D013625:Takayasu Arteritis / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome