title: Rhabdomyolysis following laparoscopic gastric bypass.
abstract: Rhabdomyolysis is a rare complication of serious surgical procedures, and constitutes a clinical and biochemical syndrome, caused by injury and destruction of skeletal muscles. It is accompanied by pain in the region of the referred muscle group, increase in creatine phosphokinase levels, myoglobinuria, often with severe renal failure, and finally multi-organ system failure and death, if not treated in time. The main risk factor in the development of postoperative rhabdomyolysis is prolonged intraoperative immobilization of the patient. Morbidly obese patients who undergo laparoscopic bariatric operations should be considered high-risk for rhabdomyolysis, from extended immobilization and pressure phenomena in the lumbar region and gluteal muscles. We report a 20-year-old woman with BMI 51, who underwent a prolonged laparoscopic Roux-en-Y gastric bypass. Postoperatively, she presented severe myalgia in the gluteal muscles and lumbar region, oliguria and creatine phosphokinase levels that reached 38,700 U/L. She was treated with intensive hydration and analgesics, and did not develop acute renal failure because diagnosis and treatment were attained immediately.
authors.affiliation: Bariatric Unit, Department of Surgical Oncology, Medical School, University of Crete, Heraklion, Crete, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Filis
authors.forename: M
authors.initials: M
authors.lastname: Daskalakis
authors.forename: I
authors.initials: I
authors.lastname: Askoxylakis
authors.forename: M
authors.initials: M
authors.lastname: Metaxari
authors.forename: J
authors.initials: J
authors.lastname: Melissas
mesh_terms: D000328:Adult; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects*; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D009767:Obesity, Morbid / Q000601:surgery*; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy