Circadian pathway: the other shoe drops.
Three new papers report the long-awaited functional characterization of the Drosophila receptor for the circadian-rhythm-regulating signalling molecule PIGMENT DISPERSING FACTOR (PDF). The discovery of the PDF receptor heralds progress in understanding the circadian pacemaker circuit and output pathways in insects.
Holmes
Todd C
TC
Department of Biology, New York University, New York 10003, USA.
Sheeba
Vasu
V
D000818:Animals; D002450:Cell Communication / Q000235:genetics / Q000502:physiology; D002940:Circadian Rhythm / Q000235:genetics* / Q000502:physiology; D004330:Drosophila / Q000235:genetics* / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000235:genetics* / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled / Q000235:genetics* / Q000378:metabolism
D029721:Drosophila Proteins; D009479:Neuropeptides; C507073:PDFR protein, Drosophila; D043562:Receptors, G-Protein-Coupled; C113883:pdf protein, Drosophila