Comparison between mismatch negativity amplitude and magnetic mismatch field strength in normal adults.
The auditory mismatch negativity (MMN) or its magnetic counterpart (magnetic mismatch field, MMF) has been widely used to assess the ability of stimulus-driven change detection process in humans. The authors evaluated the similarity of inter-individual variation of the response strength between MMN and MMF recordings. Three types of MMN or MMF were recorded in ten healthy subjects: change in duration of pure-tone stimuli, change in duration of the Japanese vowel /a/, and difference between the Japanese vowels /a/ and /o/. There was no significant correlation between MMN amplitude and MMF strength under any condition and in either hemisphere. These results suggest that widely used indices of MMN in the two technologies, i.e., EEG-amplitude and MEG-ECD may not be proportional in an individual. To further clarify the differential significance of recording MMN/MMF may be important to establish MMN/MMF as clinical indices of individual ability of preattentive stage of auditory processing.
Kudo
Noriko
N
Department of Cognitive and Information Sciences, Graduate School of Humanities, Chiba University, Chiba, Japan.
Kasai
Kiyoto
K
Itoh
Kenji
K
Koshida
Ichiro
I
Yumoto
Masato
M
Kato
Masato
M
Kamio
Satoru
S
Araki
Tsuyoshi
T
Nakagome
Kazuyuki
K
Fukuda
Masato
M
Yamasue
Hidenori
H
Yamada
Haruyasu
H
Abe
Osamu
O
Kato
Nobumasa
N
Iwanami
Akira
A
D000328:Adult; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008297:Male; D017603:Signal Detection, Psychological