title: [Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in patients with solid organ transplantation: a clinical, neurophysiological and neuropathological study of 4 cases].
abstract: BACKGROUND
  Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) rarely develops in patients with solid organ transplantation.
  
  
  METHODS
  We describe the clinical, biological, electrophysiological and neuropathological features of 4 patients with solid organ transplantation who developed CIDP. Two patients had liver transplantation, one had kidney transplantation and one had lung transplantation.
  
  
  RESULTS
  All 4 patients developed in the months following transplantation a syndrome that fulfilled criteria for definite CIDP. All patients had immunosuppressive therapy, with ciclosporin + prednisolone in 2 cases, tacrolimus in 1 case and azathioprine + prednisolone + ciclosporin in one case. One patient had chronic HCV and HBV infection. Treatment with intravenous immune globulin (IVIG) and/or a change in immunosuppressive therapy improved the neuropathy in all cases.
  
  
  CONCLUSIONS
  CIDP is a rare and potentially treatable condition that should be considered in all patients with solid organ transplantation who develop a rapidly disabling sensorimotor polyneuropathy.
authors.affiliation: Département de Neurologie, Hôpital Civil, Strasbourg. Echniz-Laguna@medecine.u-strasbg.fr
authors.forename: A
authors.initials: A
authors.lastname: Echaniz-Laguna
authors.forename: M
authors.initials: M
authors.lastname: Anheim
authors.forename: P
authors.initials: P
authors.lastname: Wolf
authors.forename: R
authors.initials: R
authors.lastname: Kessler
authors.forename: G
authors.initials: G
authors.lastname: Massard
authors.forename: M
authors.initials: M
authors.lastname: Mohr
authors.forename: B
authors.initials: B
authors.lastname: Moulin
authors.forename: L
authors.initials: L
authors.lastname: Braun-Parvez
authors.forename: D
authors.initials: D
authors.lastname: Jaeck
authors.forename: C
authors.initials: C
authors.lastname: Tranchant
mesh_terms: D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D016031:Liver Transplantation / Q000009:adverse effects*; D016040:Lung Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology