Metastasis of uterine leiomyosarcoma to the pancreas.
BACKGROUND
Metastasis of uterine leiomyosarcoma to the pancreas is extremely rare.


METHODS
A 46-year-old woman presented with hypermenorrhea and dysmenorrhea and underwent surgery. The histologic and immunohistochemical diagnosis was uterine leiomyosarcoma stage I with no metastasis to the ovaries or the pelvic lymph nodes. The mitotic count was very high. Thereafter, recurrences in the lung and subsequently in the pancreas were detected. The lesions in the lung and pancreas were resected and diagnosed as metastases of uterine leiomyosarcoma based on histology and immunohistochemistry.


CONCLUSIONS
We report an extraordinarily rare case of uterine leiomyosarcoma with metastasis to the pancreas following initial metastasis to the lung, both of which were diagnosed using histology and immunohistochemistry of the specimens obtained at surgery.
Iwamoto
Ichiro
I
Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan. ichiro@m.kufm.kagoshima-u.ac.jp
Fujino
Toshinori
T
Higashi
Yohichi
Y
Tsuji
Takahiro
T
Nakamura
Noboru
N
Komokata
Teruo
T
Douchi
Tsutomu
T
D000199:Actins / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D014594:Uterine Neoplasms / Q000473:pathology
D000199:Actins