title: Histomorphometric and mechanical analysis of the hydroxyapatite-bone interface after electromagnetic stimulation: an experimental study in rabbits.
abstract: We investigated the effect of stimulation with a pulsed electromagnetic field on the osseointegration of hydroxyapatite in cortical bone in rabbits. Implants were inserted into femoral cortical bone and were stimulated for six hours per day for three weeks. Electromagnetic stimulation improved osseointegration of hydroxyapatite compared with animals which did not receive this treatment in terms of direct contact with the bone, the maturity of the bone and mechanical fixation. The highest values of maximum push-out force (F(max)) and ultimate shear strength (sigma(u)) were observed in the treated group and differed significantly from those of the control group at three weeks (F(max); p < 0.0001; sigma(u), p < 0.0005).
authors.affiliation: Experimental Surgery Laboratory, Research Institute Codivilla-Putti, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy. milena.fini@ior.it
authors.forename: M
authors.initials: M
authors.lastname: Fini
authors.forename: G
authors.initials: G
authors.lastname: Giavaresi
authors.forename: R
authors.initials: R
authors.lastname: Giardino
authors.forename: F
authors.initials: F
authors.lastname: Cavani
authors.forename: R
authors.initials: R
authors.lastname: Cadossi
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D018483:Diaphyses / Q000473:pathology; D017886:Durapatite / Q000737:chemistry*; D004574:Electromagnetic Fields; D005269:Femur / Q000473:pathology; D006622:Hip Prosthesis; D007595:Joint Prosthesis; D008297:Male; D008422:Materials Testing / Q000379:methods; D016348:Osseointegration; D011817:Rabbits; D033081:Shear Strength
chemical_list: D017886:Durapatite