title: First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes.
abstract: Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae.
authors.affiliation: Federal Environmental Agency, FG II 3.3, Corrensplatz 1, 14195 Berlin, Germany. karina.preussel@uba.de
authors.forename: Karina
authors.initials: K
authors.lastname: Preussel
authors.forename: Anke
authors.initials: A
authors.lastname: Stüken
authors.forename: Claudia
authors.initials: C
authors.lastname: Wiedner
authors.forename: Ingrid
authors.initials: I
authors.lastname: Chorus
authors.forename: Jutta
authors.initials: J
authors.lastname: Fastner
mesh_terms: D000470:Alkaloids; D046890:Aphanizomenon / Q000302:isolation & purification* / Q000378:metabolism*; D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; D005618:Fresh Water / Q000382:microbiology*; D005858:Germany; D014498:Uracil / Q000031:analogs & derivatives* / Q000096:biosynthesis
chemical_list: D000470:Alkaloids; D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; C089595:cylindrospermopsin; D014498:Uracil