title: Association between epithelial cell death and invasion by microspheres conjugated to Porphyromonas gingivalis vesicles with different types of fimbriae.
abstract: Microspheres (MS) conjugated to Porphyromonas gingivalis vesicles with type II fimbriae were the most efficient human epithelial cell invaders among the six types. Cell death was induced by MS, though becoming less frequent over time, with invasion efficiency partially related to cell death and gingipains likely the major cause.
authors.affiliation: Department of Oral Frontier Biology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita-Osaka 565-0871, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Inaba
authors.forename: Shinji
authors.initials: S
authors.lastname: Kawai
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kato
authors.forename: Ichiro
authors.initials: I
authors.lastname: Nakagawa
authors.forename: Atsuo
authors.initials: A
authors.lastname: Amano
mesh_terms: D018829:Adhesins, Bacterial / Q000378:metabolism; D017209:Apoptosis / Q000502:physiology; D016866:Bacteroidaceae Infections / Q000382:microbiology / Q000473:pathology; D002473:Cell Wall / Q000502:physiology; D002478:Cells, Cultured; D003546:Cysteine Endopeptidases / Q000378:metabolism; D004847:Epithelial Cells / Q000382:microbiology* / Q000473:pathology*; D010861:Fimbriae, Bacterial / Q000502:physiology*; D000080867:Gingipain Cysteine Endopeptidases; D006367:HeLa Cells; D006801:Humans; D008863:Microspheres; D016966:Porphyromonas gingivalis / Q000502:physiology*
chemical_list: D018829:Adhesins, Bacterial; D000080867:Gingipain Cysteine Endopeptidases; D003546:Cysteine Endopeptidases