title: [Methicillin-resistant Staphylococcus aureus (MRSA) in chronic wounds: therapeutic options and perspectives].
abstract: The contamination of chronic wounds with Methicillin-resistant Staphylococcus aureus (MRSA) represents a world-wide increasing problem. Although it is still unclear whether bacterial contamination is a relevant factor for delayed wound-healing, verification of MRSA contamination has significant logistic consequences for the medical institution as well as for the patient. In particular, if MRSA contamination progresses towards a systemic infection, options for antibiotic therapy are greatly limited. In this article, we discuss current therapeutic standards and potential alternatives for eradication of MRSA. There is evident need for effective, novel approaches for elimination of MRSA from chronic wounds that avoid the development of bacterial resistance; otherwise therapeutic alternatives for antibacterial treatment of chronic wounds will become more limited.
authors.affiliation: Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen. joachimdissemond@hotmail.com
authors.forename: Joachim
authors.initials: J
authors.lastname: Dissemond
authors.forename: Andreas
authors.initials: A
authors.lastname: Körber
authors.forename: Michaela
authors.initials: M
authors.lastname: Lehnen
authors.forename: Steohan
authors.initials: S
authors.lastname: Grabbe
mesh_terms: D002908:Chronic Disease; D024881:Drug Resistance, Bacterial; D006801:Humans; D016106:Methicillin Resistance; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D013203:Staphylococcal Infections / Q000628:therapy*; D014946:Wound Infection / Q000628:therapy*