Characterization of the rhesus monkey superior olivary complex by calcium binding proteins and synaptophysin.
This study was performed in order to characterize the main nuclei of the rhesus monkey superior olivary complex by means of antibodies against the calcium binding proteins parvalbumin, calbindin and calretinin and the synaptic vesicle protein synaptophysin. These markers revealed the neuronal morphology and organization of nuclei located within the rhesus monkey superior olivary complex. The architectural details included the distribution of axonal terminals on neurons. The medial superior olivary nucleus was present as a column of neurons. No clear segregation of calretinin-positive terminals was noticed on the medial and lateral dendritic fields of these neurons. The lateral superior olivary nucleus was characterized by a distinct nuclear shape. Calretinin-, parvalbumin- or calbindin-positive terminals contacted somata and dendrites. The medial nucleus of trapezoid body could be clearly differentiated as a distinct region in the rhesus monkey superior olivary complex. Somata of that nucleus showed calbindin- and parvalbumin-labelling whereas somatic calyces of Held were reavealed by calretinin and synaptophysin labelling. The results are discussed with respect to the processing of acoustic information in primate species and their ability to hear high and low frequencies, which is reflected by anatomical correlates.
Bazwinsky
Ivonne
I
Institute of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, Halle, Germany. ivonne.bazwinsky@medizin.uni-halle.de
Bidmon
Hans-Jürgen
HJ
Zilles
Karl
K
Hilbig
Heidegard
H
D000818:Animals; D001306:Auditory Pathways / Q000502:physiology*; D015415:Biomarkers / Q000032:analysis; D064032:Calbindin 2; D064026:Calbindins; D002135:Calcium-Binding Proteins / Q000032:analysis*; D005260:Female; D007150:Immunohistochemistry / Q000379:methods; D008252:Macaca fascicularis / Q000033:anatomy & histology*; D008856:Microscopy, Fluorescence; D009847:Olivary Nucleus / Q000033:anatomy & histology* / Q000737:chemistry; D010320:Parvalbumins / Q000032:analysis; D064030:S100 Calcium Binding Protein G / Q000032:analysis; D016708:Synaptophysin / Q000032:analysis*
D015415:Biomarkers; D064032:Calbindin 2; D064026:Calbindins; D002135:Calcium-Binding Proteins; D010320:Parvalbumins; D064030:S100 Calcium Binding Protein G; D016708:Synaptophysin