title: Self-assembling a molecular pegboard.
abstract: This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a "molecular pegboard". We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations.
authors.affiliation: Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287, USA.
authors.forename: Kyle
authors.initials: K
authors.lastname: Lund
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Stuart
authors.initials: S
authors.lastname: Lindsay
authors.forename: Hao
authors.initials: H
authors.lastname: Yan
mesh_terms: D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry*; D046228:Microarray Analysis; D018625:Microscopy, Atomic Force; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D019809:Streptavidin / Q000737:chemistry
chemical_list: D004247:DNA; D019809:Streptavidin