title: [Determination of cinnabar in zijinhong capsules by high performance liquid chromatography].
abstract: A high performance liquid chromatographic method was established for the determination of cinnabar in Zijinhong capsules using diethyldithiocarbamate (DEDTC) chelate. A Waters X-Terra C18 column was used with a mixture of methanol-0.01 mol/L Na2HPO4 (pH 7.5) (containing 0.01% DEDTC) (73:27, V/V) as the mobile phase and a detector set at 270 nm. The calibration curve was linear (r = 0. 999 6) in the range of 10.1 mg/L - 100.9 mg/L of Hg2+. The recoveries were 97.0% - 100.8% with RSDs of 1.8% - 2.3%.
authors.affiliation: Institute for Drug and Instrument Control of Health Department, General Logistic Department of PLA, Beijing 100071, China.
authors.forename: Ai-Ying
authors.initials: AY
authors.lastname: Kong
authors.forename: Xiong-Ping
authors.initials: XP
authors.lastname: Jiang
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Wei
mesh_terms: D002214:Capsules; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D017669:Mercury Compounds / Q000032:analysis*
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D017669:Mercury Compounds; C034211:cinnabar