title: Comparative randomised active drug controlled clinical trial of a herbal eye drop in computer vision syndrome.
abstract: A comparative double-blind placebo-controlled clinical trial of a herbal eye drop (itone) was conducted to find out its efficacy and safety in 120 patients with computer vision syndrome. Patients using computers for more than 3 hours continuously per day having symptoms of watering, redness, asthenia, irritation, foreign body sensation and signs of conjunctival hyperaemia, corneal filaments and mucus were studied. One hundred and twenty patients were randomly given either placebo, tears substitute (tears plus) or itone in identical vials with specific code number and were instructed to put one drop four times daily for 6 weeks. Subjective and objective assessments were done at bi-weekly intervals. In computer vision syndrome both subjective and objective improvements were noticed with itone drops. Itone drop was found significantly better than placebo (p<0.01) and almost identical results were observed with tears plus (difference was not statistically significant). Itone is considered to be a useful drug in computer vision syndrome.
authors.affiliation: Susrut Eye Foundation & Research Centre, Kolkata.
authors.forename: Pranab Kr
authors.initials: PK
authors.lastname: Chatterjee
authors.forename: Debasis
authors.initials: D
authors.lastname: Bairagi
authors.forename: Sudipta
authors.initials: S
authors.lastname: Roy
authors.forename: Nilay Kr
authors.initials: NK
authors.lastname: Majumder
authors.forename: Ratish Ch
authors.initials: RCh
authors.lastname: Paul
authors.forename: Sunil Ch
authors.initials: SCh
authors.lastname: Bagchi
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003201:Computers; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D028321:Plant Preparations / Q000627:therapeutic use*; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D009883:Ophthalmic Solutions; D028321:Plant Preparations