Synthesis of crescent aromatic oligoamides.
[structures: see text] This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.
Yuan
Lihua
L
Department of Chemistry, The State University of New York at Buffalo, Buffalo, New York 14260, USA.
Sanford
Adam R
AR
Feng
Wen
W
Zhang
Aimin
A
Zhu
Jin
J
Zeng
Huaqiang
H
Yamato
Kazuhiro
K
Li
Minfeng
M
Ferguson
Joseph S
JS
Gong
Bing
B
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000577:Amides