Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli.
A new norditerpenoid and a known alkaloid were isolated from the alkaloidal fraction of the processed tubers of Aconitum carmichaeli. The structure of the new norditerpenoid alkaloid was elucidated as lipoforesaconitine (1) on the basis of spectroscopic analysis. The known norditerpenoid alkaloid was characterized as lipoyunanaconitine (2). In addition, a new flavonoid, 6"-O-acetylliquiritin (7), along with a known ceramide, (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxylignoceroylamino]-8(E)-octadecene-1,3,4-triol (3), as well as a known steroid saponin, gracillin (8), and three known flavonoids, liquiritigenin (4), isoliquiritigenin (5), and liquiritin (6), were also isolated and characterized. All known compounds were isolated from this plant for the first time. The structures of the isolates were established by spectroscopic and chemical methods.
Shim
Sang Hee
SH
Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
Lee
So Young
SY
Kim
Ju Sun
JS
Son
Kun Ho
KH
Kang
Sam Sik
SS
D000107:Acetylation; D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D002240:Carbohydrate Sequence; D002681:China; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry; D013055:Spectrophotometry, Infrared
D000470:Alkaloids; D004224:Diterpenes