[Grounds for treatment of patients with infectious-allergic rhinitis with bacterial allergens].
We studied mechanisms of cell and humoral immunity in the course of allergen-specific immunotherapy (ASIT) with bacterial allergens in patients with infectious-allergic rhinosinusitis (IAR). Measurements of cytokines determining the type of immune response in conduction of ASIT with bacterial allergens (IL-2 and IL-6) have demonstrated that ASIT shifted cytokines balance to prevalence of Th1 cells. Good and excellent results were achieved in 80% IAR patients. Thus, T-lymphocyte activation of immune system is essential in the mechanism of IAR formation.
Baranova
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Pochinina
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Kostina
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D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000276:immunology / Q000627:therapeutic use*; D000942:Antigens, Bacterial; D016207:Cytokines / Q000276:immunology; D003888:Desensitization, Immunologic / Q000379:methods*; D006801:Humans; D007111:Immunity, Cellular; D008213:Lymphocyte Activation / Q000276:immunology; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D016896:Treatment Outcome
D000485:Allergens; D000942:Antigens, Bacterial; D016207:Cytokines