title: Amiodarone in treatment of fetal supraventricular tachycardia. A case report and review of literature.
abstract: We report a case of nonimmune hydrops fetalis detected at 32 weeks of gestation. Fetal heart rate was 300 beats per minute. Ultrasound and fetal Doppler echocardiography showed it to be due to supraventricular tachycardia (SVT). Following failed maternal therapy with digoxin alone, amiodarone with digoxin was used. Conversion to sinus rhythm and resolution of hydrops followed this treatment. Since there is no ideal treatment protocol for these cases at present, we reviewed reports of transplacental treatment of SVT.
authors.affiliation: Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, U.P., India. mandakini@sgpgi.ac.in
authors.forename: Mandakini
authors.initials: M
authors.lastname: Pradhan
authors.forename: Mrs
authors.initials: M
authors.lastname: Manisha
authors.forename: Renu
authors.initials: R
authors.lastname: Singh
authors.forename: Aditya
authors.initials: A
authors.lastname: Kapoor
mesh_terms: D000328:Adult; D000638:Amiodarone / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004077:Digoxin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015150:Echocardiography, Doppler; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis / Q000209:etiology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013617:Tachycardia, Supraventricular / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016216:Ultrasonography, Prenatal
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D000638:Amiodarone