Magnetic resonance spectroscopy-guided transperineal prostate biopsy and brachytherapy for recurrent prostate cancer.
Brachytherapy targeted to the peripheral zone with magnetic resonance imaging (MRI) guidance is a prostate cancer treatment option with potentially fewer complications than other treatments. Follow-up MRI when failure is suspected is, however, difficult because of radiation-induced changes. Furthermore, MR spectroscopy (MRS) is compromised by susceptibility artifacts from radioactive seeds in the peripheral zone. We report a case in which combined MRI/MRS was useful for the detection of prostate cancer in the transitional zone in patients previously treated with MR-guided brachytherapy. We propose that MRI/MRS can help detect recurrent prostate cancer, guide prostate biopsy, and help manage salvage treatment decisions.
Barnes
Agnieszka Szot
AS
Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. aszot@partners.org
Haker
Steven J
SJ
Mulkern
Robert V
RV
So
Minna
M
D'Amico
Anthony V
AV
Tempany
Clare M
CM
D001706:Biopsy / Q000379:methods; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000532:radiotherapy*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000532:radiotherapy*