Successful treatment of cervical spinal epidural abscess by combined hyperbaric oxygenation.
A 49-year-old man underwent hyperbaric oxygen (HBO) therapy for the treatment of primary spinal epidural abscess. Although the epidural abscess was initially treated with antibiotic (cefozopran) for 5 days, he subsequently developed motor weakness, paresthesia and urinary retention. MRI demonstrated spinal cord compression at the C1-C4 level. HBO therapy was added to the antibiotic regimen, and three days later we found clinical evidence of a response to treatment. Neurological symptoms were relieved 13 days after HBO therapy. This case suggests that HBO therapy is an effective therapeutic adjunct for the treatment of spinal epidural abscess.
Kohshi
Kiyotaka
K
Department of Neurosurgery and Division of Hyperbaric Medicine, University Hospital of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan. k-kohshi@clnc.uoeh-u.ac.jp
Abe
Haruhiko
H
Mizoguchi
Yoshito
Y
Shimokobe
Masayuki
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D020802:Epidural Abscess / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D008297:Male; D016920:Meningitis, Bacterial / Q000628:therapy*; D008875:Middle Aged; D009333:Neck; D013117:Spinal Cord Compression / Q000175:diagnosis; D000097586:Cefozopran
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000097586:Cefozopran