title: Initial Candida dubliniensis isolate in Candida spp. positive haemocultures in Turkey between 2001 and 2004.
abstract: Candida dubliniensis which was first recognized in 1995 can be easily misidentified because of its phenotypic similarities with Candida albicans. In this study blood samples of patients from various departments of Ankara University Medical Faculty between January 2001-June 2004 were investigated for the distribution of Candida spp. and the presence of C. dubliniensis. Culture positive 67 fungi were included to the study. Phenotypic tests such as chlamydospore formation, colony morphology on Staib agar, growth at 45 degrees C, carbohydrate assimilation profiles were investigated for identification and differentiation of C. dubliniensis from C. albicans. To confirm the results polymerase chain reaction were used for suspected C. albicans and C. dubliniensis isolates. Among 38 germ tube and chlamydospore forming isolates, 37 of them were found as C. albicans and one as C. dubliniensis. The incidence of C. dubliniensis in our hospital is still low, this is the first C. dubliniensis isolate as an agent of candidaemia reported from Turkey.
authors.affiliation: Department of Microbiology and Clinical Microbiology, Ibn-I Sina Hospital, Ankara University School of Medicine, Turkey. tekeli@dialup.ankara.edu.tr
authors.forename: Alper
authors.initials: A
authors.lastname: Tekeli
authors.forename: Ozay Arikan
authors.initials: OA
authors.lastname: Akan
authors.forename: Esra
authors.initials: E
authors.lastname: Koyuncu
authors.forename: Istar
authors.initials: I
authors.lastname: Dolapci
authors.forename: Sevil
authors.initials: S
authors.lastname: Uysal
mesh_terms: D002175:Candida / Q000145:classification* / Q000302:isolation & purification / Q000502:physiology; D002177:Candidiasis / Q000382:microbiology*; D004271:DNA, Fungal / Q000235:genetics; D016469:Fungemia / Q000382:microbiology*; D006784:Hospitals, Teaching; D006801:Humans; D016133:Polymerase Chain Reaction; D014421:Turkey
chemical_list: D004271:DNA, Fungal