title: Unusually high alkaline phosphatase due to intestinal isoenzyme in a healthy adult.
abstract: Intestinal alkaline phosphatase (ALP) is more prevalent in individuals of blood group O or B, and increases after a meal, especially on a high-fat diet. We did not realize that clinicians could underestimate the importance of fasting for ALP measurement until one healthy adult showed a huge difference in ALP levels before and after a meal. We report a case of transient hyperphosphatasemia resulting in unnecessary workup due to intestinal ALP in a healthy adult of blood group O.
authors.affiliation: Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea. sungran@ajou.ac.kr
authors.forename: Sung R
authors.initials: SR
authors.lastname: Cho
authors.forename: Young A
authors.initials: YA
authors.lastname: Lim
authors.forename: Wee G
authors.initials: WG
authors.lastname: Lee
mesh_terms: D000017:ABO Blood-Group System; D000469:Alkaline Phosphatase / Q000378:metabolism*; D005215:Fasting / Q000378:metabolism; D006262:Health; D006801:Humans; D007422:Intestines / Q000201:enzymology*; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D008875:Middle Aged
chemical_list: D000017:ABO Blood-Group System; D007527:Isoenzymes; D000469:Alkaline Phosphatase