[Different patterns of abnormalities in exercise 201TI myocardial scintigraphy and their mechanisms].
OBJECTIVE
To categorize the patterns of abnormalities in exercise (201)TI myocardial scintigraphy and explore the mechanisms.


METHODS
Exercise (201)TI myocardial scintigraphy was performed in 203 patients with clinically suspected coronary artery disease, including 74 normotensive patients, 78 hypertensive patients without left ventricle hypertrophy (LVH) and 51 hypertensive patients with LVH. All the patients underwent coronary angiography one month before or after (201)TI myocardial scintigraphy, and the patterns of abnormal findings were categorized as segmental, non-segmental and mixed patterns. Patients with abnormal (201)TI myocardial perfusion and normal coronary angiographic findings were followed up.


RESULTS
In hypertensive patients without and with LVH, the ratios of abnormal perfusion in segmental, non-segmental and mixed types were 52/60 and 32/58, 4/60 and 9/58, and 4/60 and 17/58, respectively. The ratios of normal coronary angiography in the 3 types were 17/84, 13/13 and 10/21, respectively. Among the 40 patients followed up, 5 with segmental abnormality and 2 with mixed abnormalities developed large coronary artery disease, which was found in none of the patients with segmental abnormality.


CONCLUSIONS
In hypertensive patients with and without LVH, segmental perfusion abnormalities may be attributed to the anatomic and functional stenosis of the large coronary arteries, and the non-segmental abnormal perfusion might be only possible with coronary microvascular diseases.
Ouyang
Wei
W
Department of Nuclear Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. oyw88@163.net
Qian
Xue-xian
XX
He
Guo-rong
GR
Liu
Jin-hua
JH
D003327:Coronary Disease / Q000150:complications / Q000000981:diagnostic imaging*; D005080:Exercise Test / Q000379:methods; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000000981:diagnostic imaging; D008297:Male; D011875:Radionuclide Angiography / Q000379:methods; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
D013794:Thallium Radioisotopes