Supramolecular oxidation of anilines using hydrogen peroxide as stoichiometric oxidant.
6A,6D-Di-O-(propan-2-on-1,3-diyl) alpha-cyclodextrin-6A,6D-dicarboxylate (2alpha) and 6A,6D-di-O-(propan-2-on-1,3-diyl) beta-cyclodextrin-6A,6D-dicarboxylate (2beta) were found to catalyze the oxidation of aromatic amines in the presence of hydrogen peroxide. The products were the corresponding nitro compounds or in some cases azo-, azoxy-, or other dimerization products. The catalysis was found to follow enzyme kinetics giving a rate increase (kcat/kuncat) of up to 1100 in the best case.
Marinescu
Lavinia
L
Department of Chemistry, University of Aarhus, DK-8000, Denmark.
Mølbach
Merete
M
Rousseau
Cyril
C
Bols
Mikael
M