title: A simple tool to predict exercise capacity of obese patients with ischaemic heart disease.
abstract: OBJECTIVE
  To define an equation that predicts exercise capacity taking into account body mass index (BMI).
  
  
  METHODS
  Retrospective analysis and validation study of a multidisciplinary programme aimed at weight loss and physical rehabilitation.
  
  
  METHODS
  Tertiary referral hospital.
  
  
  METHODS
  372 consecutive obese participants (249 men) with stable ischaemic heart disease, aged mean 60.1 (SD 8.7) years, underwent a treadmill exercise test. BMI was 37.8 (4.5) kg/m(2). In the validation study the model was tested in 87 patients with similar characteristics.
  
  
  RESULTS
  Mean exercise intensity was 6.6 (SD 2.4) metabolic equivalents (METs). Multivariate linear regression analysis defined two simple models that considered exercise intensity as the dependent variable and a set of independent variables such as anthropometric measures, age and sex in the first one, plus associated clinical conditions and drug treatment in the second one. The correlation coefficients of the two models were R = 0.630 and R = 0.677, respectively. Age, BMI and sex were the strongest predictors of exercise capacity. The first derived equation efficiently predicted exercise capacity: in the validation study predicted exercise intensity was 6.3 (1.6) METs and attained exercise intensity was 6.3 (2.4) METs (p = 0.903) with a highly significant correlation (R = 0.534, p < 0.001).
  
  
  CONCLUSIONS
  BMI is an important determinant of exercise capacity of obese people with ischaemic heart disease. The use of a simple equation may help in predicting exercise capacity, in individualising exercise protocol and in setting up rehabilitation programs for obese patients.
authors.affiliation: Unit of Cardiac Rehabilitation, Ospedale San Giuseppe, IRCCS, Istituto Auxologico Italiano, Verbania, Italy. gondoni@auxologico.it
authors.forename: L A
authors.initials: LA
authors.lastname: Gondoni
authors.forename: A
authors.initials: A
authors.lastname: Liuzzi
authors.forename: A M
authors.initials: AM
authors.lastname: Titon
authors.forename: O
authors.initials: O
authors.lastname: Taronna
authors.forename: F
authors.initials: F
authors.lastname: Nibbio
authors.forename: P
authors.initials: P
authors.lastname: Ferrari
authors.forename: G
authors.initials: G
authors.lastname: Leonetti
mesh_terms: D015992:Body Mass Index; D005080:Exercise Test / Q000379:methods; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D015397:Program Evaluation; D012189:Retrospective Studies; D013318:Stroke Volume / Q000502:physiology; D015431:Weight Loss