Cardiovascular fitness and physical activity in children with and without impaired glucose tolerance.
OBJECTIVE
To examine differences in cardiovascular fitness (VO(2max)) and physical activity levels in overweight Hispanic children with normal glucose tolerance (NGT) vs impaired glucose tolerance (IGT).


METHODS
A total of 173 overweight (BMI percentile 97.0 +/- 3.1) Hispanic children ages 8-13 years with a family history of type 2 diabetes.


METHODS
VO(2max) was measured via a maximal effort treadmill test and open circuit spirometry. Physical activity was determined by questionnaire. Glucose tolerance was established by a 2-h oral glucose challenge (1.75 g of glucose/kg body weight). IGT was defined from an oral glucose tolerance test as a 2-h plasma glucose level > or =140 and <200 mg/dl.


RESULTS
IGT was detected in 46 of the 173 participants (approximately 27%); no cases of type 2 diabetes were identified. No significant differences were found between youth with NGT and those with IGT in absolute VO(2max) (2.2 +/- 0.6 vs 2.1 +/- 0.5 l/min), VO(2max) adjusted for gender, age, and body composition (2.2 +/- 0.2 vs 2.1 +/- 0.2 l/min), or recreational physical activity levels (8.7 +/- 8.2 vs 6.9 +/- 6.2 h/week).


CONCLUSIONS
Overweight Hispanic youth with IGT exhibit similar levels of VO(2max) and physical activity compared to their NGT counterparts. Longitudinal analyses are necessary to determine whether fitness/activity measures contribute significantly to diabetes risk over time in this group.
Shaibi
G Q
GQ
Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, 90033, USA.
Ball
G D C
GD
Cruz
M L
ML
Weigensberg
M J
MJ
Salem
G J
GJ
Goran
M I
MI
D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics; D015444:Exercise; D005080:Exercise Test / Q000379:methods; D005260:Female; D020022:Genetic Predisposition to Disease; D018149:Glucose Intolerance / Q000097:blood / Q000503:physiopathology*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D009043:Motor Activity; D050177:Overweight / Q000502:physiology*; D010101:Oxygen Consumption; D010809:Physical Fitness; D011236:Prediabetic State / Q000097:blood / Q000503:physiopathology*
D001786:Blood Glucose; D007328:Insulin