[Polymethyleneamine alkaloids of animal origin. I. Metabolites of marine and microbial organisms].
This review, issued in two parts, describes the information on the structure and biological activity of animal alkaloids derived from polymethyleneamines and produced by marine organisms, wasps, spiders, and microorganisms. Animal alkaloids are outstanding models for developing methods and drugs for the treatment of many human diseases. In the first part, we consider compounds produced by marine and microbial organisms. Some promising synthetic analogues of these alkaloids are used in developing modem preparations for the chelate therapy of excessive blood iron content and antituberculosis, antiproliferative, and immunosuppressive drugs. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 6; see also http://www.maik.ru.
Rogoza
L N
LN
Salakhutdinov
N F
NF
Tolstikov
G A
GA
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D000818:Animals; D001419:Bacteria / Q000737:chemistry; D005658:Fungi / Q000737:chemistry; D008386:Marine Biology; D011073:Polyamines / Q000737:chemistry* / Q000302:isolation & purification; D013112:Spiders / Q000737:chemistry; D014863:Wasps / Q000737:chemistry
D000470:Alkaloids; D011073:Polyamines