title: Glomerulonephritis associated with chronic infection from long-term central venous catheterization.
abstract: There have been few reports on immune complex-mediated glomerulonephritis associated with chronic infection from long-term central venous catheterization in adulthood. We report here on a 13-year-old boy with nephritis who exhibited glomerulonephritis that had been induced by the long-term use of central venous catheters, and its resolution after extraction of the central venous catheter. A diagnosis of glomerulonephritis associated with chronic infection caused by long-term central venous catheterization was made, based on the absence of clinical findings after removal of the catheter, hypocomplementemia, pathology findings resembling membranoproliferative glomerulonephritis, and detection of Staphylococcus epidermidis from culture of the removed catheter culture. For clinicians using long-term central venous access for parenteral feeding, rapid catheter exchange is necessary for patients with fever of unknown origin.
authors.affiliation: Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima City, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Ohara
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Kawasaki
authors.forename: Kei
authors.initials: K
authors.lastname: Takano
authors.forename: Masato
authors.initials: M
authors.lastname: Isome
authors.forename: Ruriko
authors.initials: R
authors.lastname: Nozawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Hosoya
mesh_terms: D000293:Adolescent; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects* / Q000382:microbiology; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D016331:Parenteral Nutrition, Home; D013203:Staphylococcal Infections / Q000209:etiology*; D013212:Staphylococcus epidermidis