title: A case of vulvitis granulomatosa.
abstract: Merkersson-Rosenthal syndrome (MRS) is characterized by cheilitis or pareitis granulomatosa, facial palsy, and fissured tongue. Sometimes the forehead, eyelids and chin are involved, and occasionally genital lesions are present. A vulval lesion of MRS is named vulvitis granulomatosa. Tranilast has been described as an effective treatment for cases of MRS, granulomatous cheilitis, and granulomatous blepharitis. Herein we report a successful treatment with tranilast of an adult female patient with vulvitis granulomatosa.
authors.affiliation: Department of Dermatology, Kitasato University School of Medicine, Kanagawa, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Tsuboi
authors.forename: Mikio
authors.initials: M
authors.lastname: Masuzawa
authors.forename: Kensei
authors.initials: K
authors.lastname: Katsuoka
mesh_terms: D005260:Female; D006099:Granuloma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D014847:Vulvitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D062367:ortho-Aminobenzoates / Q000627:therapeutic use
chemical_list: D062367:ortho-Aminobenzoates; C012293:tranilast