title: Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment. Case report.
abstract: OBJECTIVE
  We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance.
  
  
  METHODS
  Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection (ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX.
  
  
  CONCLUSIONS
  Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide.
authors.affiliation: Department of Obstetrics and Gynaecology, Akdeniz University, School of Medicine, Antalya, Turkey. imendilcioglu@yahoo.com
authors.forename: Inanc
authors.initials: I
authors.lastname: Mendilcioglu
authors.forename: Mualla
authors.initials: M
authors.lastname: Ozcan
authors.forename: Gulseren
authors.initials: G
authors.lastname: Bagci
authors.forename: Mehmet
authors.initials: M
authors.lastname: Simsek
authors.forename: Sinan
authors.initials: S
authors.lastname: Kursun
authors.forename: Guven
authors.initials: G
authors.lastname: Luleci
authors.forename: Omur
authors.initials: O
authors.lastname: Taskin
mesh_terms: D004200:Diseases in Twins / Q000000981:diagnostic imaging / Q000209:etiology / Q000235:genetics*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging / Q000209:etiology / Q000235:genetics*; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D011123:Polyploidy; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D020554:Sperm Injections, Intracytoplasmic; D014463:Ultrasonography