title: [Fetal lung development on MRT. Normal course and impairment due to premature rupture of membranes].
abstract: A well-organized interplay between many molecular factors as well as mechanical forces influence fetal lung development. At the end of this complex process a sufficiently sized and structurally mature organ should ensure the postnatal survival of the newborn. Besides prenatal ultrasonography, magnetic resonance imaging (MRI) can now be used to investigate normal and pathological human lung growth in utero. Oligohydramnios, due to premature rupture of membranes (PROM), is an important risk factor for compromised fetal lung growth. In these situations MR volumetry can be used to measure the size of the fetal lung quite accurately. Together with the evaluation of lung signal intensities on T2-weighted sequences, fetuses with pulmonary hypoplasia can be readily detected.
authors.affiliation: Klinik für Radiodiagnostik, Medizinische Universität Wien. gregor.kasprian@meduniwien.ac.at
authors.forename: G
authors.initials: G
authors.lastname: Kasprian
authors.forename: P C
authors.initials: PC
authors.lastname: Brugger
authors.forename: H
authors.initials: H
authors.lastname: Helmer
authors.forename: M
authors.initials: M
authors.lastname: Langer
authors.forename: C
authors.initials: C
authors.lastname: Balassy
authors.forename: D
authors.initials: D
authors.lastname: Prayer
mesh_terms: D005321:Extraembryonic Membranes / Q000473:pathology*; D005315:Fetal Diseases / Q000175:diagnosis; D006801:Humans; D008168:Lung / Q000196:embryology* / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000196:embryology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011296:Prenatal Diagnosis / Q000379:methods*; D012422:Rupture, Spontaneous / Q000196:embryology / Q000473:pathology