title: Chronic fatigue syndrome of childhood. Comparative study with emotional disorders.
abstract: OBJECTIVE
  To examine clinical specificity in chronic fatigue syndrome (CFS) of childhood, by comparing clinical features in childhood CFS and in emotional disorders (ED). METHOD SAMPLE: 28 children with CFS; 27 with ED.
  
  
  METHODS
  History of disorder; K-SADS psychiatric interviews; self-esteem and physical symptoms questionnaires; premorbid history, behavioural and personality assessments.
  
  
  RESULTS
  There were high levels of comorbid emotional disorders in children with CFS, and the two groups were comparable on self-esteem, but CFS children endorsed more fatigue and other somatic symptoms. The two groups were comparable on age at illness onset, but parents of children with CSF reported more biological illness precipitants, more pre-morbid recurrent medical problems and infections. The CFS group had fewer pre-morbid psychological problems and less psychiatric comorbidity than the ED group.
  
  
  CONCLUSIONS
  There is considerable clinical overlap between CFS and ED of childhood, but there are also differences in clinical presentation between these disorders.
authors.affiliation: Academic Unit of Child and Adolescent Psychiatry, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK. e.garralda@imperial.ac.uk
authors.forename: M Elena
authors.initials: ME
authors.lastname: Garralda
authors.forename: Luiza
authors.initials: L
authors.lastname: Rangel
mesh_terms: D000293:Adolescent; D002648:Child; D015897:Comorbidity; D015673:Fatigue Syndrome, Chronic / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D008131:London / Q000453:epidemiology; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D010554:Personality Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology