Helicobacter pylori infection and gastric MALT lymphoma.
Helicobacter pylori infection is implicated in the development of two different gastric cancers: gastric adenocarcinoma and gastric MALT lymphoma. The association with the gastric MALT lymphoma is strong and causal. It is currently the only cancer which can be treated by a simple antibiotic treatment. However, the evolution of an H. pylori infection towards lymphoma is exceptional. Host susceptibility factors and environmental factors predisposing a patient to lymphoma have not yet been determined. The bacterial factors are currently being identified.
Lehours
P
P
INSERM-ERI 10, Centre National de Réfrénce des Campylobacters et Hélicobacters Laboratoire de Bactériologie, CHU Pellegrin, Bordeaux, France. philippe.lehours@labhel.u-bordeaux2.fr
Mégraud
F
F
D016481:Helicobacter Infections / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000472:pathogenicity*; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000382:microbiology* / Q000473:pathology; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000473:pathology