title: West Nile virus infection in a teenage boy with acute lymphocytic leukemia in remission.
abstract: West Nile Virus (WNV) infection is an important cause of encephalitis. Although the medical literature contains examples of WNV encephalitis in susceptible, mainly elderly, immunocompromised hosts, few case reports have described pediatric cases. The authors describe an adolescent with acute lymphocytic leukemia and WNV encephalitis. Surveillance studies indicate an increase in WNV activity. Physicians need to be aware of WNV activity in their community and consider WNV as a potential source of infection.
authors.affiliation: Children's Hospital of The King's Daughters, Norfolk, VA 23510, USA. hindohk@chkd.org
authors.forename: Heather
authors.initials: H
authors.lastname: Hindo
authors.forename: E Stephen
authors.initials: ES
authors.lastname: Buescher
authors.forename: L Matthew
authors.initials: LM
authors.lastname: Frank
authors.forename: Dee
authors.initials: D
authors.lastname: Pettit
authors.forename: Christopher
authors.initials: C
authors.lastname: Dory
authors.forename: Rebecca
authors.initials: R
authors.lastname: Byrd
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D002442:Ceftazidime / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D009033:Culicidae; D003937:Diagnosis, Differential; D018792:Encephalitis, Viral / Q000175:diagnosis; D017809:Fatal Outcome; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007299:Insect Bites and Stings / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D015122:Mercaptopurine / Q000008:administration & dosage; D009657:North Carolina / Q000208:ethnology; D018458:Persistent Vegetative State / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000008:administration & dosage; D014640:Vancomycin / Q000627:therapeutic use; D014750:Vincristine / Q000008:administration & dosage; D014768:Virginia; D014901:West Nile Fever / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014902:West Nile virus / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D014750:Vincristine; D014640:Vancomycin; D002443:Ceftriaxone; D002442:Ceftazidime; D015122:Mercaptopurine; D011241:Prednisone; D000212:Acyclovir