Room-temperature Cannizzaro reaction under mild conditions facilitated by magnesium bromide ethyl etherate and triethylamine.
[reaction: see text] A room-temperature convenient Cannizzaro reaction prompted by magnesium bromide ethyl etherate and triethylamine is described for smooth conversion of aromatic aldehydes into their respective alcohols and carboxylic acids. The methodology is applicable to both inter- and intramolecular reactions and could be directed to obtain the carboxylic moiety in the form of an acid, an amide, or an ester compound depending on the selected reaction conditions or workup procedure.
Abaee
M Saeed
MS
Organic Chemistry Laboratory, Chemistry & Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran. abaee@ccerci.ac.ir
Sharifi
Roholah
R
Mojtahedi
Mohammad M
MM