Clathrin-mediated endocytosis before fluorescent proteins.
The recent technological advance of using fluorescent proteins to image endocytic protein traffic has resulted in a greater understanding of this dynamic process. However, most of the main concepts for how clathrin-mediated endocytosis functions were formulated long before intrinsically fluorescent proteins were available. These important conceptual breakthroughs came from the clever interpretation of simple observations.
Roth
Michael G
MG
Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA. michael.roth@utsouthwestern.edu
D000818:Animals; D001695:Biology / Q000266:history*; D002966:Clathrin / Q000378:metabolism*; D004705:Endocytosis; D011992:Endosomes / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D049673:History, 20th Century; D006801:Humans; D008164:Luminescent Proteins / Q000032:analysis
D002966:Clathrin; D008164:Luminescent Proteins