title: Evidence of resilience: neuroimaging in former prisoners of war.
abstract: In this study, single voxel proton magnetic resonance spectroscopic imaging ((1)H-MRS) and volumetric analysis of hippocampal magnetic resonance imaging (MRI) images were used to determine if any differences in hippocampal biochemistry or volume were present between former prisoners of war (POWs) with and without posttraumatic stress disorder (PTSD) and control subjects matched for age and education. This study did not find lower hippocampal concentrations of N-acetylaspartate (NAA), smaller hippocampal volumes, or more impaired memory function in older veterans with PTSD compared with a group matched for traumatic experience or a nontraumatized control group.
authors.affiliation: Mental Health Service, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA. THOMAS.FREEMAN@MED.VA.GOV
authors.forename: Thomas
authors.initials: T
authors.lastname: Freeman
authors.forename: Tim
authors.initials: T
authors.lastname: Kimbrell
authors.forename: Leroy
authors.initials: L
authors.lastname: Booe
authors.forename: Michael
authors.initials: M
authors.lastname: Myers
authors.forename: David
authors.initials: D
authors.lastname: Cardwell
authors.forename: Diana M
authors.initials: DM
authors.lastname: Lindquist
authors.forename: John
authors.initials: J
authors.lastname: Hart
authors.forename: Richard A
authors.initials: RA
authors.lastname: Komoroski
mesh_terms: D000368:Aged; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D003710:Demography; D006624:Hippocampus / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008568:Memory; D011329:Prisoners / Q000523:psychology*; D013313:Stress Disorders, Post-Traumatic / Q000378:metabolism* / Q000523:psychology*; D014857:Warfare
chemical_list: D001224:Aspartic Acid; C000179:N-acetylaspartate