title: Comparison between mismatch negativity amplitude and magnetic mismatch field strength in normal adults.
abstract: The auditory mismatch negativity (MMN) or its magnetic counterpart (magnetic mismatch field, MMF) has been widely used to assess the ability of stimulus-driven change detection process in humans. The authors evaluated the similarity of inter-individual variation of the response strength between MMN and MMF recordings. Three types of MMN or MMF were recorded in ten healthy subjects: change in duration of pure-tone stimuli, change in duration of the Japanese vowel /a/, and difference between the Japanese vowels /a/ and /o/. There was no significant correlation between MMN amplitude and MMF strength under any condition and in either hemisphere. These results suggest that widely used indices of MMN in the two technologies, i.e., EEG-amplitude and MEG-ECD may not be proportional in an individual. To further clarify the differential significance of recording MMN/MMF may be important to establish MMN/MMF as clinical indices of individual ability of preattentive stage of auditory processing.
authors.affiliation: Department of Cognitive and Information Sciences, Graduate School of Humanities, Chiba University, Chiba, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Kudo
authors.forename: Kiyoto
authors.initials: K
authors.lastname: Kasai
authors.forename: Kenji
authors.initials: K
authors.lastname: Itoh
authors.forename: Ichiro
authors.initials: I
authors.lastname: Koshida
authors.forename: Masato
authors.initials: M
authors.lastname: Yumoto
authors.forename: Masato
authors.initials: M
authors.lastname: Kato
authors.forename: Satoru
authors.initials: S
authors.lastname: Kamio
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Araki
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Nakagome
authors.forename: Masato
authors.initials: M
authors.lastname: Fukuda
authors.forename: Hidenori
authors.initials: H
authors.lastname: Yamasue
authors.forename: Haruyasu
authors.initials: H
authors.lastname: Yamada
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.forename: Nobumasa
authors.initials: N
authors.lastname: Kato
authors.forename: Akira
authors.initials: A
authors.lastname: Iwanami
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008297:Male; D017603:Signal Detection, Psychological