Prenatal diagnosis of trisomy 9.
Fetal trisomy 9, especially its nonmosaic form, is a rare chromosomal abnormality and there are only 8 cases reported to have been sonographically detected in the prenatal period. We report a case of nonmosaic fetal trisomy 9, mimicking trisomy 13 on sonographic findings at 32 weeks' gestation. Although the incidence of trisomy 9 is rare, diagnosing trisomy 9 is important because the sonographic features are similar to those of trisomies 13 and 18, and cannot to be identified by routine fluorescencein situ hybridization. Because nonmosaic trisomy 9 is universally lethal, correct diagnosis and appropriate counseling is essential in patient care and clinical management.
Nakagawa
Miki
M
Department of Obstetrics, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Japan.
Hashimoto
Kazumasa
K
Ohira
Hiroki
H
Hamanaka
Takuro
T
Ozaki
Mamoru
M
Suehara
Noriyuki
N
D000328:Adult; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D014314:Trisomy / Q000175:diagnosis* / Q000473:pathology; D016216:Ultrasonography, Prenatal