title: Ulysses - an application for the projection of molecular interactions across species.
abstract: We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses.
authors.affiliation: Center for Genomics and Bioinformatics, Karolinska Institutet, 171 77 Stockholm, Sweden. danielle@cmmt.ubc.ca
authors.forename: Danielle
authors.initials: D
authors.lastname: Kemmer
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Sohrab P
authors.initials: SP
authors.lastname: Shah
authors.forename: Jonathan
authors.initials: J
authors.lastname: Lim
authors.forename: Jochen
authors.initials: J
authors.lastname: Brumm
authors.forename: Macaire M S
authors.initials: MM
authors.lastname: Yuen
authors.forename: John
authors.initials: J
authors.lastname: Ling
authors.forename: Tao
authors.initials: T
authors.lastname: Xu
authors.forename: Wyeth W
authors.initials: WW
authors.lastname: Wasserman
authors.forename: B F Francis
authors.initials: BF
authors.lastname: Ouellette
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D006801:Humans; D023421:Models, Animal; D025941:Protein Interaction Mapping / Q000379:methods*; D012984:Software; D013045:Species Specificity; D014584:User-Computer Interface