Amiodarone in treatment of fetal supraventricular tachycardia. A case report and review of literature.
We report a case of nonimmune hydrops fetalis detected at 32 weeks of gestation. Fetal heart rate was 300 beats per minute. Ultrasound and fetal Doppler echocardiography showed it to be due to supraventricular tachycardia (SVT). Following failed maternal therapy with digoxin alone, amiodarone with digoxin was used. Conversion to sinus rhythm and resolution of hydrops followed this treatment. Since there is no ideal treatment protocol for these cases at present, we reviewed reports of transplacental treatment of SVT.
Pradhan
Mandakini
M
Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, U.P., India. mandakini@sgpgi.ac.in
Manisha
Mrs
M
Singh
Renu
R
Kapoor
Aditya
A
D000328:Adult; D000638:Amiodarone / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004077:Digoxin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015150:Echocardiography, Doppler; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis / Q000209:etiology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013617:Tachycardia, Supraventricular / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016216:Ultrasonography, Prenatal
D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D000638:Amiodarone