Absolute configuration of amino alcohols by 1H-NMR.
A general NMR spectroscopy protocol for determination of absolute configuration of 1,2-amino alcohols, that allows differentiation of the four possible stereoisomers by analysis of the 1H NMR spectra of their bis-MPA derivatives, is described.
Leiro
Victoria
V
Departamento de Química Orgánica, Facultad de Química y Unidad de RMN de Biomoléculas Asociada al CSIC, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
Freire
Félix
F
Quiñoá
Emilio
E
Riguera
Ricardo
R