title: Identification of deep-sea-sediment bacteria which produce tetrodotoxin.
abstract: Forty-nine bacterial strains were isolated from deep-sea sediments. Among them, 22 strains were shown by the tissue culture assay method to produce sodium channel blockers. For some strains, high-performance liquid chromatography analysis confirmed that the blocker was tetrodotoxin. Tetrodotoxin-producing bacteria seem to be widespread in marine sediment.
authors.affiliation: Department of Marine Microbiology, Ocean Research Institute, University of Tokyo, Minamidai, Nakano, Tokyo 164, Japan.
authors.forename: H K
authors.initials: HK
authors.lastname: Do
authors.forename: K
authors.initials: K
authors.lastname: Kogure
authors.forename: U
authors.initials: U
authors.lastname: Simidu