Correlation study of toxicity of substituted phenols to river bacteria and their biodegradability in river water.
OBJECTIVE
To study the correlation of toxicity with biodegradability (BODT) in order to promote QSBR development and understand the degradation mechanism.


METHODS
Toxicity of substituted phenols to river bacteria was determined by the turbidities that were measured using a spectrophotometer (UV-190) at 530 nm against a blank control. The biodegradability of substituted phenols was expressed as BODT and the DO concentrations were determined by the iodometric titration method.


RESULTS
The BODT and toxicity(log 1/IC50) of 12 substituted phenols to bacteria from the Songhua River were determined respectively. The correlation of biodegradability with toxicity was developed: BODT=8.21 (+/-2.22) pKa -32.44 (+/-8.28) log 1/IC50 +89.04 (+/-38.20), n=12, R2=0.791, R2(adj)=0.745, SE=9.134, F=17.066, P=0.001.


CONCLUSIONS
The BODT of substituted phenols was influenced by their toxicity and the ionization constant pKa. The stronger the toxicity, the less readily the compound was degraded by river bacteria.
Yuan
Xing
X
Department of Environmental Science, Northeast Normal University, Changchun 130024, Jilin, China. yuanx@nenu.edu.cn
Lu
Guang-Hua
GH
Su
Li-Min
LM
D001419:Bacteria / Q000378:metabolism; D001673:Biodegradation, Environmental; D003627:Data Interpretation, Statistical; D008954:Models, Biological; D010636:Phenols / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*; D045483:Rivers / Q000382:microbiology; D014874:Water Pollutants, Chemical / Q000378:metabolism* / Q000633:toxicity*
D010636:Phenols; D014874:Water Pollutants, Chemical