title: Clinical and prognostic aspects of laryngeal clear cell carcinoma.
abstract: Clear cell carcinoma (CCC) of the larynx is a rare pathological finding; only eight cases are described in the literature. It occurs in older adults and shows a predilection for men. We report the ninth observation of laryngeal CCC in the literature. We reviewed the literature and correlated the prognosis of the tumour according to its site of onset and treatment. The literature review showed that this neoplasm is highly aggressive, with a high recurrence rate and short mean survival time; the treatment of choice is surgery, and chemo- or radiotherapy are used mainly for the treatment of recurrences.
authors.affiliation: Institute of Otolaryngology-Head and Neck Surgery, University of Naples Federico II, Naples, Italy. domenictesta@libero.it
authors.forename: Domenico
authors.initials: D
authors.lastname: Testa
authors.forename: Vieri
authors.initials: V
authors.lastname: Galli
authors.forename: Gaetano
authors.initials: G
authors.lastname: de Rosa
authors.forename: Renata
authors.initials: R
authors.lastname: Iovine
authors.forename: Stefania
authors.initials: S
authors.lastname: Staibano
authors.forename: Pasquale
authors.initials: P
authors.lastname: Somma
authors.forename: Chiara
authors.initials: C
authors.lastname: Mignogna
authors.forename: Maurizio
authors.initials: M
authors.lastname: Iengo
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000628:therapy; D011379:Prognosis