title: Early liver cancer: concepts, diagnosis, and management.
abstract: Hepatocellular carcinoma is a major health problem worldwide. The prognosis of patients depends on the stage when the disease is diagnosed. For the early detection of these tumors, both the selection of patients at high risk and effective surveillance programs are important. When the tumor is diagnosed early, patients can choose potentially curative treatment, including surgical resection, transplantation, and ablation therapy. Here, we give an overview of the present management of hepatocellular carcinoma. Further studies in diagnosis, treatment, and prevention are required to achieve the best clinical management of this disease.
authors.affiliation: Department of Gastroenterology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. yoshidah-2im@h.u-tokyo.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Yoshida
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Yoshida
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Shiina
authors.forename: Masao
authors.initials: M
authors.lastname: Omata
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D003952:Diagnostic Imaging; D042241:Early Diagnosis; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D016031:Liver Transplantation; D009367:Neoplasm Staging
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor