Implant infection and infection resistant materials: a mini review.
Implant infection is an aggressive, often irreducible post-surgical infection. It remains the primary cause of implant failure. Bacterial contamination during surgery and subsequent adhesion onto biomaterial surface of opportunistic microorganisms, such as staphylococcal species, exopolysaccharidic slimes or specific adhesins, initiates the implant infection. Pathogenesis of periprosthestic infection is the focus of studies aimed at developing infection resistant materials.
Arciola
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Research Unit on Implant Infections, Rizzoli Orthopedic Institute, Bologna, Italy. carlarenata.arciola@ior.it
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Campoccia
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D000208:Acute Disease; D018829:Adhesins, Bacterial / Q000378:metabolism; D018441:Biofilms; D002908:Chronic Disease; D020099:Coated Materials, Biocompatible / Q000737:chemistry / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D006801:Humans; D016459:Prosthesis-Related Infections / Q000382:microbiology* / Q000503:physiopathology / Q000517:prevention & control*; D012307:Risk Factors
D018829:Adhesins, Bacterial; D020099:Coated Materials, Biocompatible