title: Metastasis of uterine leiomyosarcoma to the pancreas.
abstract: BACKGROUND
  Metastasis of uterine leiomyosarcoma to the pancreas is extremely rare.
  
  
  METHODS
  A 46-year-old woman presented with hypermenorrhea and dysmenorrhea and underwent surgery. The histologic and immunohistochemical diagnosis was uterine leiomyosarcoma stage I with no metastasis to the ovaries or the pelvic lymph nodes. The mitotic count was very high. Thereafter, recurrences in the lung and subsequently in the pancreas were detected. The lesions in the lung and pancreas were resected and diagnosed as metastases of uterine leiomyosarcoma based on histology and immunohistochemistry.
  
  
  CONCLUSIONS
  We report an extraordinarily rare case of uterine leiomyosarcoma with metastasis to the pancreas following initial metastasis to the lung, both of which were diagnosed using histology and immunohistochemistry of the specimens obtained at surgery.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan. ichiro@m.kufm.kagoshima-u.ac.jp
authors.forename: Ichiro
authors.initials: I
authors.lastname: Iwamoto
authors.forename: Toshinori
authors.initials: T
authors.lastname: Fujino
authors.forename: Yohichi
authors.initials: Y
authors.lastname: Higashi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuji
authors.forename: Noboru
authors.initials: N
authors.lastname: Nakamura
authors.forename: Teruo
authors.initials: T
authors.lastname: Komokata
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Douchi
mesh_terms: D000199:Actins / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D014594:Uterine Neoplasms / Q000473:pathology
chemical_list: D000199:Actins