title: Uterine liposarcoma in a young woman: a case report.
abstract: Liposarcoma of uterus is a very rare neoplasm encountered generally in the sixth or seventh decade of life. We reported the eighth case of uterine liposarcoma with extension to broad ligament in a 23-year-old woman who presented with pelvic pain, dysuria, and rapidly enlarging pelvic mass. During laparotomy, the mass was detected to be originated from the uterine cervix. In frozen section, no definitive diagnosis was established, and for preservation of fertility, extirpation of the mass was performed. The histopathologic examination of the specimen revealed liposarcoma. The tumor cells were diffusely and intensively immune reactive for vimentin and S-100, and negative for smooth muscle actin, desmin, h-caldesmon, pan cytokeratin, and CD10. Staining with periodic acid and Schiff, alcian blue, mucicarmine, and epithelial membrane antigen (EMA) were negative. No recurrence was detected in the postoperative seventh month. Present case is the youngest patient with uterine liposarcoma and also the first case detected in reproductive period.
authors.affiliation: Department of Obstetrics and Gynecology, Zeynep Kamil Women and Children Diseases Education and Research Hospital, Uskudar, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Karateke
authors.forename: A
authors.initials: A
authors.lastname: Gurbuz
authors.forename: C
authors.initials: C
authors.lastname: Kabaca
authors.forename: A
authors.initials: A
authors.lastname: Alkan
authors.forename: G
authors.initials: G
authors.lastname: Kir
authors.forename: H
authors.initials: H
authors.lastname: Cetiner
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008080:Liposarcoma / Q000473:pathology* / Q000628:therapy; D015080:Mesna / Q000008:administration & dosage; D020011:Protective Agents / Q000008:administration & dosage; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy
chemical_list: D020011:Protective Agents; D004317:Doxorubicin; D015080:Mesna; D007069:Ifosfamide