A case of acute thallotoxicosis successfully treated with double-filtration plasmapheresis.
The authors report a 48-year-old Chinese woman who presented with acute peripheral neuritis with progressive alopecia. Laboratory examinations disclosed a high blood concentration of thallium (97 microg/L) versus a normal value (0.9 microg/L), and she was diagnosed as having acute thallotoxicosis. After her hospitalization, the cutantest of dimercaptopropansulfonate sodium was positive and the patient refused to take Prussian blue because it caused constipation. She rapidly entered remission after assistance via double-filtration plasmapheresis (DFPP), suggesting the potential efficacy of DFPP for thallotoxicosis.
Tian
Ying Ran
YR
Department of Neurology, Xi'jing Hospital, Fourth Military Medical University, No. 15 West Chang'le Road, Xi'an 710032, PR China.
Sun
Li Li
LL
Wang
Wen
W
Du
Fong
F
Song
Ai Xia
AX
Ni
Chun Yan
CY
Zhu
Qing
Q
Wan
Qi
Q
D005260:Female; D006801:Humans; D008875:Middle Aged; D009443:Neuritis / Q000097:blood / Q000139:chemically induced / Q000628:therapy*; D010523:Peripheral Nervous System Diseases / Q000097:blood / Q000628:therapy*; D010956:Plasmapheresis / Q000379:methods*; D013793:Thallium / Q000097:blood / Q000633:toxicity*
D013793:Thallium