title: Coronary-artery calcium scores using electron beam CT in patients with chronic renal failure.
abstract: We evaluated the risk of coronary-artery disease in patients with chronic renal failure (CRF) by measuring the coronary-artery calcium scores with electron beam CT (EBCT). A total of 81 CRF patients were divided into three groups; pre-dialysis (group I, n = 35), hemodialysis (group II, n = 31) and peritoneal dialysis (group III, n = 15). The several serum biochemical markers and calcium score levels by EBCT were determined. The Ca x P products were significantly higher in groups II (p < 0.05) and III (p < 0.01) than in group I. The serum calcium levels were significantly higher in group III than in both group I (p < 0.01) and II (p < 0.05). The serum calcium level in 15 patients with a calcium score > 400 was significantly higher than the 66 patients with a score < or =400 (p < 0.01). The calcium score was significantly higher in the 15 patients with cardiovascular complications than in the 66 patients without cardiovascular complications (628.9+/-904.8 vs. 150.4+/-350.9, p < 0.01). EBCT seemed to be a good diagnostic tool for evaluating the risk of coronary-artery disease ''noninvasively'' in CRF patients who are at increased risk of cardiovascular morbidity and mortality.
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Chan-Duck
authors.initials: CD
authors.lastname: Kim
authors.forename: Ji-Hyung
authors.initials: JH
authors.lastname: Cho
authors.forename: Hyuk-Joon
authors.initials: HJ
authors.lastname: Choi
authors.forename: Min-Hwa
authors.initials: MH
authors.lastname: Jang
authors.forename: Hyeog-Man
authors.initials: HM
authors.lastname: Kwon
authors.forename: Jun-Chul
authors.initials: JC
authors.lastname: Kim
authors.forename: Sun-Hee
authors.initials: SH
authors.lastname: Park
authors.forename: Jong-Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Dong-Kyu
authors.initials: DK
authors.lastname: Cho
authors.forename: Yong-Lim
authors.initials: YL
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000378:metabolism; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000209:etiology / Q000378:metabolism; D003331:Coronary Vessels / Q000378:metabolism*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D002118:Calcium