Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst.
5-Pyrrolidin-2-yltetrazole performs as a useful organocatalyst for the asymmetric addition of malonates to a range of enones, with good to excellent enantioselectivities.
Knudsen
Kristian Rahbek
KR
Department of Chemistry, University of Cambridge, Lensfield Rd, Cambridge, UKCB2 1EW.
Mitchell
Claire E T
CE
Ley
Steven V
SV