Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma.
This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined by quantifying the number of apoptotic bodies per hundred cells (apoptotic index) on haematoxylin and eosin stained histological sections [corrected] A significant correlation was noted between increasing apoptotic indices and increasing Gleason grades within a cancer.
Sherwani
Rana
R
Department of Pathology & General Surgery, J.N. Medical College, Aligarh Muslim University, Aligarh. ranasherwani@yahoo.com
Khan
Sabina
S
Khan
Nazoora
N
Kamran
Mohd
M
Husain
Musharraf
M
D000368:Aged; D017209:Apoptosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000473:pathology; D019048:Prostatic Intraepithelial Neoplasia / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*