Severe pneumonia during primary infection with an atypical strain of Toxoplasma gondii in an immunocompetent young man.
We report a case of severe acute primary pulmonary toxoplasmosis in an immunocompetent young man living in Nice (Southern France). The Toxoplasma DNA extracted from the broncho-alveolar lavage fluid allowed a genetic characterization of the responsible strain which displayed an atypical genotype of Toxoplasma gondii. This unusual genetic composition of the parasite may have influenced, among other factors, the severity of the disease.
De Salvador-Guillouët
Francine
F
Centre Hospitalier-Universitaire de Nice, Service d'Infectiologie, Hôpital de l'Archet, BP 3079 06202--Nice Cedex 3, France. de-salvador.f@chu-nice.fr
Ajzenberg
Daniel
D
Chaillou-Opitz
Sylvie
S
Saint-Paul
Marie-Christine
MC
Dunais
Brigitte
B
Dellamonica
Pierre
P
Marty
Pierre
P
D000328:Adult; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D014122:Toxoplasma / Q000145:classification*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000469:parasitology*
D000981:Antiprotozoal Agents