Unusually high alkaline phosphatase due to intestinal isoenzyme in a healthy adult.
Intestinal alkaline phosphatase (ALP) is more prevalent in individuals of blood group O or B, and increases after a meal, especially on a high-fat diet. We did not realize that clinicians could underestimate the importance of fasting for ALP measurement until one healthy adult showed a huge difference in ALP levels before and after a meal. We report a case of transient hyperphosphatasemia resulting in unnecessary workup due to intestinal ALP in a healthy adult of blood group O.
Cho
Sung R
SR
Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea. sungran@ajou.ac.kr
Lim
Young A
YA
Lee
Wee G
WG
D000017:ABO Blood-Group System; D000469:Alkaline Phosphatase / Q000378:metabolism*; D005215:Fasting / Q000378:metabolism; D006262:Health; D006801:Humans; D007422:Intestines / Q000201:enzymology*; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D008875:Middle Aged
D000017:ABO Blood-Group System; D007527:Isoenzymes; D000469:Alkaline Phosphatase