title: Benign multicystic peritoneal mesothelioma: cases reports in the family with diverticulosis and literature review.
abstract: We report on benign multicystic peritoneal mesothelioma in two siblings whose family had a history of multiple familial diseases including diverticulosis. After a genetic evaluation and a chromosomal analysis, we were not able to identify a specific genetic cause of the family's pattern of disease. We assumed that previous surgical procedures and the chronic inflammatory process from diverticulitis were the underlying etiology. Both patients had multiple recurrences with indolent courses similar to those reported in other cases. After the recurrences, one patient was treated with cystic aspiration and the other with hormones. The cysts in both cases regressed partially but the patients were relieved of their clinical symptoms, for 2 years after cystic drainage in one case and for 5 years after hormonal treatment in the other.
authors.affiliation: Department of Gynecologic Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
authors.forename: S
authors.initials: S
authors.lastname: Tangjitgamol
authors.forename: J
authors.initials: J
authors.lastname: Erlichman
authors.forename: H
authors.initials: H
authors.lastname: Northrup
authors.forename: A
authors.initials: A
authors.lastname: Malpica
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: E
authors.initials: E
authors.lastname: Lee
authors.forename: J J
authors.initials: JJ
authors.lastname: Kavanagh
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D004240:Diverticulum / Q000150:complications; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D018261:Mesothelioma, Cystic / Q000150:complications / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy*; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy*; D012008:Recurrence; D013396:Suction
chemical_list: D018931:Antineoplastic Agents, Hormonal