title: Pyo-pneumothorax in patients with active pulmonary tuberculosis: an analysis of 17 cases without intrapleural fibrinolytic treatment.
abstract: OBJECTIVE
  To review the medical records of patients with active pulmonary tuberculosis (TB) and pyo-pneumothorax (PPT).
  
  
  METHODS
  Medical records of 17 patients (14 male, 3 female, mean age 23.8 years, range 20-52) with PPT and active pulmonary tuberculosis at Gulhane Military Medical Academia Haydarpasa Training Hospital, Istanbul, Turkey, were reviewed from January 1998 to December 2002. The patients were treated with chest tube drainage and chemotherapy. Intrapleural fibrinolytic agents or irrigation was not performed.
  
  
  RESULTS
  Pleural fluid samples were available in 14 patients and the mean levels of LDH, protein and glucose in the pleural fluid were 1,767 +/- 944 U/l, 5.2 +/- 1.4 g/dl and 31.7 +/- 22.6 mg/dl, respectively. Mycobacterium tuberculosis was detected in the pleural effusion of 3 patients. The duration of chest tube drainage was longer in cases who underwent open drainage (p = 0.014). At the end of the treatment period 10 patients developed pleural thickening, 4 of them underwent decortication and pneumonectomy was also done in 1 patient. The development of pleural thickening was related to the level of pleural fluid glucose (p = 0.04).
  
  
  CONCLUSIONS
  This study shows that while taking care of patients with pulmonary TB the physician must be aware of the complication of PPT and that adequate chemotherapy and drainage must be duly performed.
authors.affiliation: Department of Pulmonary Diseases, Gulhane Military Medical Academia Haydarpasa Training Hospital, Istanbul, Turkey. zkartaloglu@hotmail.com
authors.forename: Z
authors.initials: Z
authors.lastname: Kartaloglu
authors.forename: O
authors.initials: O
authors.lastname: Okutan
authors.forename: T
authors.initials: T
authors.lastname: Işitmangil
authors.forename: E
authors.initials: E
authors.lastname: Kunter
authors.forename: S
authors.initials: S
authors.lastname: Sebit
authors.forename: M
authors.initials: M
authors.lastname: Apaydin
authors.forename: A
authors.initials: A
authors.lastname: Ilvan
mesh_terms: D000328:Adult; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D008889:Military Personnel; D035422:Pleural Cavity; D011030:Pneumothorax / Q000150:complications* / Q000188:drug therapy; D013492:Suppuration; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000473:pathology / Q000628:therapy; D014421:Turkey
chemical_list: D005343:Fibrinolytic Agents