title: Assessment of antibacterial activity of some topical otological solutions.
abstract: OBJECTIVE
  Otological solutions have long been used in the treatment of the bacterial and fungal infections of the ear. We investigated antibacterial activity of some otic solutions against the most common bacteria isolated from discharging ears.
  
  
  METHODS
  Three solutions were used (Castellani's, Burrow's, and 2% salicyl alcohol) for 20 fresh isolates of each of the following organisms: Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter spp.. The activity of each solution was determined by the size of the zone of inhibition of bacterial growth.
  
  
  RESULTS
  The Castellani's solution showed significantly larger average inhibition zones than the other solutions did (p<0.001).
  
  
  CONCLUSIONS
  The Castellani's solution may be considered a good option against bacterial or mixed infections (bacterial and fungal) of the ear.
authors.affiliation: Department of Otolaryngology, Medicine Faculty of Atatürk University, Erzurum, Turkey. hucuncu@atauni.edu.tr
authors.forename: Harun
authors.initials: H
authors.lastname: Uçüncü
authors.forename: A Esin
authors.initials: AE
authors.lastname: Aktaş
authors.forename: Halil
authors.initials: H
authors.lastname: Yazgi
authors.forename: Nimet
authors.initials: N
authors.lastname: Yiğit
authors.forename: Bülent
authors.initials: B
authors.lastname: Aktan
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Sütbeyaz
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010035:Otitis Media, Suppurative / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents