title: Disseminated Aspergillus fumigatus infection with consecutive mitral valve endocarditis in a lung transplant recipient.
abstract: Aspergillus infection is a known complication of lung transplantation and remains associated with high mortality rates. The manifestation of the infection varies from simple colonization of the lung to disseminated complicated infections. Early Aspergillus infection has been rarely observed in a small number of lung transplant recipients; most cases occur during the late post-operative period. The pulmonary involvement has often been described as the first clinical localization of the disease. Although other various forms of Aspergillus infection are not uncommonly encountered after lung transplantation, Aspergillus mitral valve endocarditis is rare. We present a case of disseminated Aspergillus fumigatus infection with consecutive mitral valve endocarditis having developed 78 days after double-lung transplantation for cystic fibrosis.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, J. W. Goethe University, Frankfurt am Main, Germany. M.Scherer@em.uni-frankfurt.de
authors.forename: Mirela
authors.initials: M
authors.lastname: Scherer
authors.forename: Hans-Gerd
authors.initials: HG
authors.lastname: Fieguth
authors.forename: Tayfun
authors.initials: T
authors.lastname: Aybek
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Ujvari
authors.forename: Anton
authors.initials: A
authors.lastname: Moritz
authors.forename: Gerhard
authors.initials: G
authors.lastname: Wimmer-Greinecker
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000209:etiology* / Q000473:pathology; D001232:Aspergillus fumigatus / Q000302:isolation & purification / Q000472:pathogenicity; D001927:Brain Diseases / Q000382:microbiology; D003550:Cystic Fibrosis / Q000601:surgery; D004696:Endocarditis / Q000209:etiology* / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008943:Mitral Valve / Q000382:microbiology / Q000473:pathology; D008944:Mitral Valve Insufficiency / Q000209:etiology; D011183:Postoperative Complications