Baeyer-Villiger oxidation with potassium peroxomonosulfate supported on acidic silica gel.
[reaction: see text] Potassium peroxomonosulfate deposited onto silica SiO2 x KHSO5 efficiently reacts with ketones in dichloromethane at room temperature to give the corresponding esters or lactones in quantitative yields. This method avoids hydrolysis of the reaction products. The Baeyer-Villiger reaction is catalyzed by potassium hydrogensulfate present in the supported reagent.
González-Núñez
María E
ME
Departamento de Química Orgánica, Universidad de Valencia, Avda. V. Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.
Mello
Rossella
R
Olmos
Andrea
A
Asensio
Gregorio
G