Effect of Monensin on Growth and Methanogenesis of Methanobacterium formicicum.
Monensin inhibited methanogenesis from formate but not from H(2)-CO(2) by resting-cell suspensions of Methanobacterium formicicum. The antibiotic severely inhibited growth on formate. The lag phase of H(2)-CO(2)-grown cultures was prolonged by monensin, but these cultures recovered from the initial inhibition. The recovery did not result from the development of a monensin-resistant population or inactivation of the antibiotic.
Dellinger
C A
CA
Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061.
Ferry
J G
JG