title: Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.
abstract: BACKGROUND
  Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins.
  
  
  METHODS
  We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.
authors.affiliation: Universidade Federal do Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
authors.forename: Adilha Misson Rua
authors.initials: AM
authors.lastname: Micheletti
authors.forename: Ana Cristina Araújo Lemos da
authors.initials: AC
authors.lastname: Silva
authors.forename: Antonio Geraldo
authors.initials: AG
authors.lastname: Nascimento
authors.forename: Cléber Sérgio
authors.initials: CS
authors.lastname: Da Silva
authors.forename: Eddie Fernando Candido
authors.initials: EF
authors.lastname: Murta
authors.forename: Sheila Jorge
authors.initials: SJ
authors.lastname: Adad
mesh_terms: D018322:Angiofibroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001472:Bartholin's Glands; D003560:Cysts / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery