Fluorescence based strategies for genetic analysis.
Synthetic chemistry has been central to the design of modern methods of genetic analysis. In this article, we discuss the underlying chemistry and biophysical principles that have been used in the development of robust methods for the analysis of DNA in the diagnostic laboratory.
Ranasinghe
Rohan T
RT
School of Chemistry, University of Southampton, Highfield, Southampton, UK SO17 1BJ.
Brown
Tom
T
D004247:DNA / Q000032:analysis* / Q000737:chemistry*; D015342:DNA Probes / Q000235:genetics / Q000378:metabolism; D005453:Fluorescence; D015394:Molecular Structure; D016133:Polymerase Chain Reaction
D015342:DNA Probes; D004247:DNA