A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop.
Epigenetic processes control the packaging and function of the human genome and contribute to normal and pathologic states, including cancer. The time is ripe to undertake an international effort to identify all the chemical changes and relationships between chromatin constituents that provide function to the genetic code. A timely workshop of leading experts, convened by the American Association for Cancer Research (AACR), confirmed that the technology is at hand to begin defining human epigenomes at high resolution.
Jones
Peter A
PA
University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, 90089, USA. jones_p@ccnt.hsc.usc.edu
Martienssen
Robert
R
D019175:DNA Methylation; D044127:Epigenesis, Genetic; D005786:Gene Expression Regulation; D036281:Genetic Research; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D008495:Medical Oncology / Q000458:organization & administration