Mutual information content of homologous DNA sequences.
The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DNA sequence that can be useful to identify sequences homologous to it. To reach it, we used signal processing techniques, specially spectral analysis and information theory.
Leitão
Helena Cristina G
HC
Instituto de Computação, Universidade Federal Fluminense, Niterói, RJ, Brazil. hcgl@ic.uff.br
Pessôa
Luciana S
LS
Stolfi
Jorge
J
D001483:Base Sequence; D005583:Fourier Analysis; D006801:Humans; D007257:Information Theory; D008957:Models, Genetic; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid