title: Mutual information content of homologous DNA sequences.
abstract: The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DNA sequence that can be useful to identify sequences homologous to it. To reach it, we used signal processing techniques, specially spectral analysis and information theory.
authors.affiliation: Instituto de Computação, Universidade Federal Fluminense, Niterói, RJ, Brazil. hcgl@ic.uff.br
authors.forename: Helena Cristina G
authors.initials: HC
authors.lastname: Leitão
authors.forename: Luciana S
authors.initials: LS
authors.lastname: Pessôa
authors.forename: Jorge
authors.initials: J
authors.lastname: Stolfi
mesh_terms: D001483:Base Sequence; D005583:Fourier Analysis; D006801:Humans; D007257:Information Theory; D008957:Models, Genetic; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid