A case of systemic lupus erythematosus complicated by alveolar hemorrhage and cytomegalovirus colitis.
We report a rare case of systemic lupus erythematosus (SLE) complicated by alveolar hemorrhage and cytomegalovirus (CMV) colitis. Despite the successful treatment of lupus nephritis by steroid pulse therapy, the patient developed an acute alveolar hemorrhage 2 months later. Cyclophosphamide pulse therapy ameliorated the hemorrhage. One month later, she suddenly developed melena secondary to CMV colitis. Antiviral therapy was successful. We emphasize the importance of timely and precise differential diagnosis for successful management of complicated SLE.
Takei
Masami
M
30-1 Oyaguchi Kami-machi, Itabashi-ku, Tokyo, 173-8610, Japan. numtakei@med.nihon-u.ac.jp
Yamakami
Kenji
K
Mitamura
Ko
K
Kitamura
Noboru
N
Matsukawa
Yoshihiro
Y
Sawada
Shigemasa
S
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003092:Colitis / Q000150:complications* / Q000473:pathology; D003106:Colon / Q000473:pathology; D003113:Colonoscopy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000000981:diagnostic imaging; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D011650:Pulmonary Alveoli; D011859:Radiography; D016896:Treatment Outcome; D005719:gamma-Globulins / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D005719:gamma-Globulins; D003520:Cyclophosphamide; D015774:Ganciclovir