title: Idiopathic juxtafoveal retinal telangiectasis: new findings by ultrahigh-resolution optical coherence tomography.
abstract: OBJECTIVE
  To investigate the capabilities of ultrahigh-resolution optical coherence tomography (UHR OCT); to compare with the commercially available OCT standard-resolution system, StratusOCT, for imaging of idiopathic juxtafoveal retinal telangiectasis (IJT); and to demonstrate that UHR OCT provides additional information on disease morphology, pathogenesis, and management.
  
  
  METHODS
  Retrospective, observational, interventional case series.
  
  
  METHODS
  Nineteen eyes of 10 patients diagnosed with IJT in at least one eye.
  
  
  METHODS
  All patients were imaged with UHR OCT and StratusOCT at the same visit. A subset of patients was also imaged before and after treatment of IJT.
  
  
  METHODS
  Ultrahigh- and standard-resolution cross-sectional tomograms of IJT pathology.
  
  
  RESULTS
  Using both standard- and ultrahigh-resolution OCT, we identified the following features of IJT: (1) a lack of correlation between retinal thickening on OCT and leakage on fluorescein angiography, (2) loss and disruption of the photoreceptor layer, (3) cystlike structures in the foveola and within internal retinal layers such as the inner nuclear or ganglion cell layers, (4) a unique internal limiting membrane draping across the foveola related to an underlying loss of tissue, (5) intraretinal neovascularization near the fovea, and (6) central intraretinal deposits and plaques. In 63% of cases, the presence of abnormal vessels and a discontinuity of the photoreceptor layer correlated with visual acuity.
  
  
  CONCLUSIONS
  Ultrahigh-resolution OCT improves visualization of the retinal pathology associated with IJT and allows identification of new features associated with it. Some of these features, such as discontinuity of the photoreceptor layer, are revealed only by UHR OCT.
authors.affiliation: New England Eye Center, Tufts-New England Medical Center, Tufts University, Boston, Massachusetts 02111, USA. jduker@tufts-nemc.org
authors.forename: Lelia A
authors.initials: LA
authors.lastname: Paunescu
authors.forename: Tony H
authors.initials: TH
authors.lastname: Ko
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.forename: Annie
authors.initials: A
authors.lastname: Chan
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Drexler
authors.forename: Joel S
authors.initials: JS
authors.lastname: Schuman
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D000368:Aged; D003941:Diagnostic Techniques, Ophthalmological; D004108:Dilatation, Pathologic; D005260:Female; D005584:Fovea Centralis / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology*; D012189:Retrospective Studies; D013684:Telangiectasis / Q000175:diagnosis*; D041623:Tomography, Optical Coherence / Q000379:methods*