title: Fluorescence based strategies for genetic analysis.
abstract: Synthetic chemistry has been central to the design of modern methods of genetic analysis. In this article, we discuss the underlying chemistry and biophysical principles that have been used in the development of robust methods for the analysis of DNA in the diagnostic laboratory.
authors.affiliation: School of Chemistry, University of Southampton, Highfield, Southampton, UK SO17 1BJ.
authors.forename: Rohan T
authors.initials: RT
authors.lastname: Ranasinghe
authors.forename: Tom
authors.initials: T
authors.lastname: Brown
mesh_terms: D004247:DNA / Q000032:analysis* / Q000737:chemistry*; D015342:DNA Probes / Q000235:genetics / Q000378:metabolism; D005453:Fluorescence; D015394:Molecular Structure; D016133:Polymerase Chain Reaction
chemical_list: D015342:DNA Probes; D004247:DNA