title: [Prostate cancer metastasized to thyroid cartilage: a case report].
abstract: A 75-year-old male was diagnosed as prostate cancer (serum PSA: 4,772 ng/ml, Gleason score: 4 + 4 = 8) with multiple bone metastases. And he noticed a painless mass of the frontal neck a month before the diagnosis. Computed tomography of the neck showed a tumor in the thyroid cartilage. Biopsy of the neck tumor revealed metastasis of prostate cancer by positive PSA staining. Metastasis of malignant tumor to cartilaginous tissue is extremely rare because there are usually no vessels in it. Only 4 cases of the metastasis of prostate cancer to the thyroid cartilage have been reported. It was thought that tiny bone marrows were formed in the ossified cartilage and it caused hematogenous metastasis.
authors.affiliation: Department of Urology, National Hospital Organization Osaka National Hospital.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nohara
authors.forename: Atsunari
authors.initials: A
authors.lastname: Kawashima
authors.forename: Tohru
authors.initials: T
authors.lastname: Takahashi
authors.forename: Masaya
authors.initials: M
authors.lastname: Kitamura
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Akai
authors.forename: Toshitsugu
authors.initials: T
authors.lastname: Oka
authors.forename: Masayuki
authors.initials: M
authors.lastname: Mano
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D001859:Bone Neoplasms / Q000556:secondary*; D006801:Humans; D008297:Male; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D009999:Ossification, Heterotopic / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology*; D013957:Thyroid Cartilage / Q000473:pathology*