title: [Prostate cancer with penile metastasis: a case report].
abstract: A 77-year-old man presented with complaints of dysuria, nocturia and painless nodule on his penis. Laboratory examination revealed elevated serum prostate-specific antigen (PSA) and CA19-9. Pathological examinations on prostate and penile biopsy specimens revealed prostate adenocarcinoma with penile metastasis. The patient was diagnosed as having prostate cancer stage D2 (T4N1M1) with bone, lymph node and penile metastases. There was no response to initial hormonal therapy with the surgical castration and diethylstilbestrol. However, decrease of the tumor size, as well as PSA and CA19-9 values were achieved after the combined chemotherapy with Estramustine, Paclitaxel and Carboplatin.
authors.affiliation: The Department of Urology, Kyoto University, Faculty of the Medicine.
authors.forename: Atsuro
authors.initials: A
authors.lastname: Sawada
authors.forename: Takehiko
authors.initials: T
authors.lastname: Segawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakanishi
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Shingo
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kamoto
authors.forename: Osamu
authors.initials: O
authors.lastname: Ogawa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D018395:CA-19-9 Antigen / Q000097:blood; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004961:Estramustine / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009919:Orchiectomy; D017239:Paclitaxel / Q000008:administration & dosage; D010412:Penile Neoplasms / Q000188:drug therapy / Q000556:secondary*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D004961:Estramustine; D016190:Carboplatin; D017430:Prostate-Specific Antigen; D017239:Paclitaxel