A new approach to combretastatin D2.
A concise and convergent route to combretastatin D2 is described together with some preliminary biological data.
Cousin
David
D
School of Chemistry, Queen's University Belfast, Stranmillis Rd., Belfast, UK BT9 5AG.
Mann
John
J
Nieuwenhuyzen
Mark
M
van den Berg
Hendrik
H
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001632:Bibenzyls / Q000138:chemical synthesis* / Q000494:pharmacology; D001897:Boronic Acids / Q000737:chemistry; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D002460:Cell Line; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000473:pathology; D018360:Crystallography, X-Ray; D042783:Endothelial Cells / Q000187:drug effects; D005260:Female; D006801:Humans; D007783:Lactones / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015394:Molecular Structure; D019800:Phenol / Q000737:chemistry; D010647:Phenyl Ethers / Q000138:chemical synthesis* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D013267:Stilbenes / Q000138:chemical synthesis* / Q000494:pharmacology
D000970:Antineoplastic Agents; D001632:Bibenzyls; D001897:Boronic Acids; D007783:Lactones; D010647:Phenyl Ethers; D013267:Stilbenes; C521610:combretastatin D2; D019800:Phenol; C040105:combretastatin