The laboratory in a droplet.
In this issue of Chemistry and Biology, the groups of Tawfik and Griffiths present fluorescence-activated cell sorting of double emulsions as a generally applicable screen for enzyme activity. This novel methodology increases the throughput of a typical enzyme screen by two orders of magnitude.
O'Hare
Helen M
HM
Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Johnsson
Kai
K
D002469:Cell Separation / Q000379:methods*; D004655:Emulsions / Q000737:chemistry*; D004798:Enzymes / Q000032:analysis / Q000737:chemistry*; D004926:Escherichia coli / Q000201:enzymology; D005434:Flow Cytometry / Q000379:methods*; D012680:Sensitivity and Specificity
D004655:Emulsions; D004798:Enzymes