title: Successful treatment of cervical spinal epidural abscess by combined hyperbaric oxygenation.
abstract: A 49-year-old man underwent hyperbaric oxygen (HBO) therapy for the treatment of primary spinal epidural abscess. Although the epidural abscess was initially treated with antibiotic (cefozopran) for 5 days, he subsequently developed motor weakness, paresthesia and urinary retention. MRI demonstrated spinal cord compression at the C1-C4 level. HBO therapy was added to the antibiotic regimen, and three days later we found clinical evidence of a response to treatment. Neurological symptoms were relieved 13 days after HBO therapy. This case suggests that HBO therapy is an effective therapeutic adjunct for the treatment of spinal epidural abscess.
authors.affiliation: Department of Neurosurgery and Division of Hyperbaric Medicine, University Hospital of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan. k-kohshi@clnc.uoeh-u.ac.jp
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Kohshi
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Abe
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Mizoguchi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Shimokobe
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D020802:Epidural Abscess / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D008297:Male; D016920:Meningitis, Bacterial / Q000628:therapy*; D008875:Middle Aged; D009333:Neck; D013117:Spinal Cord Compression / Q000175:diagnosis; D000097586:Cefozopran
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000097586:Cefozopran