title: Cardiovascular events in patients with coronary plaque rupture and nonsignificant stenosis.
abstract: The long-term outcome of patients who present with an identified plaque rupture in a nonflow-limiting lesion is not well known. We retrospectively studied 17 consecutive patients in whom intravascular ultrasound identified plaque rupture in nonflow-limiting lesions (minimum lumen area >4.0 mm2) that were not treated with coronary intervention. After a mean follow-up of 43 +/- 25 months, events related to those lesions were 1 death (6%) of undetermined cause (6%) that occurred after 69 months, no myocardial infarction, and 2 revascularizations (12%) that occurred at 3 and 67 months. Overall, the cumulative rate of cardiac events was 18%.
authors.affiliation: Cardiovascular Research Institute/Medstar Research Institute, Washington Hospital Center, Washington, DC, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Ohlmann
authors.forename: Sang-Wook
authors.initials: SW
authors.lastname: Kim
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Jerzy
authors.initials: J
authors.lastname: Pregowski
authors.forename: Pawel
authors.initials: P
authors.lastname: Tyczynski
authors.forename: Akiko
authors.initials: A
authors.lastname: Maehara
authors.forename: Esteban
authors.initials: E
authors.lastname: Escolar
authors.forename: Jana A
authors.initials: JA
authors.lastname: Fournadjieva
authors.forename: Augusto D
authors.initials: AD
authors.lastname: Pichard
authors.forename: Lowell F
authors.initials: LF
authors.lastname: Satler
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Kent
authors.forename: William O
authors.initials: WO
authors.lastname: Suddath
authors.forename: Ron
authors.initials: R
authors.lastname: Waksman
authors.forename: Neil J
authors.initials: NJ
authors.lastname: Weissman
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000000981:diagnostic imaging / Q000209:etiology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D023921:Coronary Stenosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D009204:Myocardial Revascularization; D011379:Prognosis; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D013997:Time Factors; D018084:Ultrasonography, Interventional