[Peculiarities of free radical and antioxidant statute in patients with systemic lupus erythematosus and rheumatoid arthritis].
The state of lipid peroxidation and antioxidant defence was investigated in sera of 66 patients with rheumatoid arthritis (RA), 50 patients with systemic lupus erythematosus (SLE) and in 235 healthy donors using the method of chemiluminescence and EPR-spectroscopy. The results indicate involvement of free radical oxidation in pathogenesis of RA and SLE. Peroxide and antioxidant imbalance was more pronounced in RA than in SLE.
Podoprigorova
V G
VG
Bobylev
A A
AA
Ivanova
S M
SM
Speranskiĭ
A I
AI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004578:Electron Spin Resonance Spectroscopy; D005260:Female; D005609:Free Radicals / Q000097:blood*; D006706:Homeostasis; D006801:Humans; D015227:Lipid Peroxidation; D049449:Luminescence; D008180:Lupus Erythematosus, Systemic / Q000097:blood*; D008297:Male; D008875:Middle Aged
D000975:Antioxidants; D005609:Free Radicals