title: Enzymic Dehalogenation of 4-Chlorobenzoyl Coenzyme A in Acinetobacter sp. Strain 4-CB1.
abstract: 4-Chlorobenzoate degradation in cell extracts of Acinetobacter sp. strain 4-CB1 occurs by initial synthesis of 4-chlorobenzoyl coenzyme A (4-chlorobenzoyl CoA) from 4-chlorobenzoate, CoA, and ATP. 4-Chlorobenzoyl CoA is dehalogenated to 4-hydroxybenzoyl CoA. Following the dehalogenation reaction, 4-hydroxybenzoyl CoA is hydrolyzed to 4-hydroxybenzoate and CoA. Possible roles for the CoA moiety in the dehalogenation reaction are discussed.
authors.affiliation: Cooperative Institute for Research in Environmental Science and Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, Colorado 80309-0215.
authors.forename: S D
authors.initials: SD
authors.lastname: Copley
authors.forename: G P
authors.initials: GP
authors.lastname: Crooks