A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximately 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.
Siddiqui
Asim S
AS
Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Research Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
Khattra
Jaswinder
J
Delaney
Allen D
AD
Zhao
Yongjun
Y
Astell
Caroline
C
Asano
Jennifer
J
Babakaiff
Ryan
R
Barber
Sarah
S
Beland
Jaclyn
J
Bohacec
Slavita
S
Brown-John
Mabel
M
Chand
Steve
S
Charest
David
D
Charters
Anita M
AM
Cullum
Rebecca
R
Dhalla
Noreen
N
Featherstone
Ruth
R
Gerhard
Daniela S
DS
Hoffman
Brad
B
Holt
Robert A
RA
Hou
Juan
J
Kuo
Byron Y-L
BY
Lee
Lisa L C
LL
Lee
Stephanie
S
Leung
Derek
D
Ma
Kevin
K
Matsuo
Corey
C
Mayo
Michael
M
McDonald
Helen
H
Prabhu
Anna-liisa
AL
Pandoh
Pawan
P
Riggins
Gregory J
GJ
de Algara
Teresa Ruiz
TR
Rupert
James L
JL
Smailus
Duane
D
Stott
Jeff
J
Tsai
Miranda
M
Varhol
Richard
R
Vrljicak
Pavle
P
Wong
David
D
Wu
Mona K
MK
Xie
Yuan-Yun
YY
Yang
George
G
Zhang
Ida
I
Hirst
Martin
M
Jones
Steven J M
SJ
Helgason
Cheryl D
CD
Simpson
Elizabeth M
EM
Hoodless
Pamela A
PA
Marra
Marco A
MA
D017398:Alternative Splicing / Q000235:genetics; D000818:Animals; D020869:Gene Expression Profiling; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D051379:Mice / Q000235:genetics*; D008810:Mice, Inbred C57BL / Q000235:genetics*; D005810:Multigene Family / Q000235:genetics; D022661:RNA, Untranslated / Q000235:genetics; D015203:Reproducibility of Results; D014158:Transcription, Genetic / Q000235:genetics
D022661:RNA, Untranslated