title: Charles Bonnet syndrome associated with a first attack of multiple sclerosis.
abstract: BACKGROUND
  We treated a rare case of Charles Bonnet syndrome (CBS) manifested during temporary blindness in both eyes caused by optic neuritis associated with a first attack of multiple sclerosis (MS).
  
  
  METHODS
  A 66-year-old Japanese woman became completely blind for 3 months due to optic neuritis after a first attack of MS. During the blind period, she experienced vivid visual hallucinations for about 2 weeks.
  
  
  METHODS
  The patient had no psychiatric disorders or cognitive impairments; therefore, the visual hallucinations during the period of blindness were indicative of CBS. Unexpectedly, the hallucinations disappeared without treatment following her recovery of vision.
  
  
  CONCLUSIONS
  Although rare, visual impairment during a first attack of MS can be associated with visual hallucinations indicative of CBS. The hallucinations can disappear spontaneously with the recovery of vision without treatment.
authors.affiliation: Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan. kkome@med.nagoya-u.ac.jp.|Department of Neurology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan. kkome@med.nagoya-u.ac.jp.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Komeima
authors.affiliation: Department of Neurology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kameyama
authors.affiliation: Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors.forename: Yozo
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000368:Aged; D001766:Blindness / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006212:Hallucinations / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis; D009902:Optic Neuritis / Q000150:complications / Q000175:diagnosis; D012075:Remission, Spontaneous; D013577:Syndrome