Cardiovascular events in patients with coronary plaque rupture and nonsignificant stenosis.
The long-term outcome of patients who present with an identified plaque rupture in a nonflow-limiting lesion is not well known. We retrospectively studied 17 consecutive patients in whom intravascular ultrasound identified plaque rupture in nonflow-limiting lesions (minimum lumen area >4.0 mm2) that were not treated with coronary intervention. After a mean follow-up of 43 +/- 25 months, events related to those lesions were 1 death (6%) of undetermined cause (6%) that occurred after 69 months, no myocardial infarction, and 2 revascularizations (12%) that occurred at 3 and 67 months. Overall, the cumulative rate of cardiac events was 18%.
Ohlmann
Patrick
P
Cardiovascular Research Institute/Medstar Research Institute, Washington Hospital Center, Washington, DC, USA.
Kim
Sang-Wook
SW
Mintz
Gary S
GS
Pregowski
Jerzy
J
Tyczynski
Pawel
P
Maehara
Akiko
A
Escolar
Esteban
E
Fournadjieva
Jana A
JA
Pichard
Augusto D
AD
Satler
Lowell F
LF
Kent
Kenneth M
KM
Suddath
William O
WO
Waksman
Ron
R
Weissman
Neil J
NJ
D000368:Aged; D000789:Angina, Unstable / Q000000981:diagnostic imaging / Q000209:etiology*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D023921:Coronary Stenosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D009204:Myocardial Revascularization; D011379:Prognosis; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D013997:Time Factors; D018084:Ultrasonography, Interventional