title: Abruptio placentae during fetal myelomeningocele repair.
abstract: Myelomeningocele (MM) is a congenital neural tube defect with serious consequences, including hydrocephaly. An important hope for intrauterine repair is that hydrocephaly may be prevented by reversing the Arnold-Chiari malformation. Three medical centers in the United States are doing trials with this objective. We describe an intrauterine correction of MM in a Brazilian research center of fetal medicine, which resulted in abruptio placentae and fetal death, to illustrate factors that influence fetal-maternal risks during this surgical procedure.
authors.affiliation: Department of Surgery, Faculdade de Ciências Médicas, Division of Pediatric Surgery and Maternal Fetal Medicine, State University of Campinas, UNICAMP, Campinas, Brazil.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Barini
authors.forename: Maria Weber G
authors.initials: MW
authors.lastname: Barreto
authors.forename: Kleber
authors.initials: K
authors.lastname: Cursino
authors.forename: Herder
authors.initials: H
authors.lastname: Zambelli
authors.forename: Adilson
authors.initials: A
authors.lastname: Prando
authors.forename: Lourenço
authors.initials: L
authors.lastname: Sbragia
mesh_terms: D000037:Abruptio Placentae / Q000209:etiology* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology*; D008591:Meningomyelocele / Q000150:complications / Q000601:surgery*; D011247:Pregnancy; D012307:Risk Factors