title: stx2vha is the dominant genotype of Shiga toxin-producing Escherichia coli O157:H7 isolated from patients and domestic animals in three regions of China.
abstract: Shiga toxin-producing Escherichia coli(STEC) O157: H7 strains were isolated from domestic animals and patients from Xuzhou City, Jiangsu Province, China and the bordering Anhui and Henan Provinces and were examined for the stx genotype. Of 390 strains, 277 were identified as genotype stx2vha ; 41, stx2 ; 51, stx2-stx1 ; 1, stx2-stx2vha-stx1 ; 5, stx2-stx2vha ; and 15 were un-typeable. Of the 277 stx2vha-bearing isolates, 116 were isolated from goats; 42, cattle; 38, hens, and 35 from pigs. The study shows stx2vha is the dominant genotype and goats are an important reservoir.
authors.affiliation: Department of Diarrhea Diseases, National Institute for Communicable Diseases Prevention and Control, China Center for Disease Prevention and Control.
authors.forename: Han
authors.initials: H
authors.lastname: Zheng
authors.forename: Huaiqi
authors.initials: H
authors.lastname: Jing
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Shengli
authors.initials: S
authors.lastname: Xia
authors.forename: Wangfu
authors.initials: W
authors.lastname: Hu
authors.forename: Shuyu
authors.initials: S
authors.lastname: Cui
authors.forename: Zhenqiang
authors.initials: Z
authors.lastname: Bi
authors.forename: Jinchuan
authors.initials: J
authors.lastname: Yang
authors.forename: Bo
authors.initials: B
authors.lastname: Pang
authors.forename: Guangfa
authors.initials: G
authors.lastname: Zhao
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.forename: Hongwei
authors.initials: H
authors.lastname: Li
authors.forename: Jianguo
authors.initials: J
authors.lastname: Xu
mesh_terms: D000818:Animals; D002417:Cattle; D002645:Chickens; D002681:China; D004197:Disease Reservoirs / Q000382:microbiology; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D005243:Feces / Q000382:microbiology; D005798:Genes, Bacterial; D006041:Goats / Q000382:microbiology; D006463:Hemolytic-Uremic Syndrome / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D022641:Shiga Toxin 2 / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity; D013552:Swine
chemical_list: D022641:Shiga Toxin 2