Adult Kawasaki disease unrelated to epstein-barr virus and group A Streptococcus.
A 23-year-old Japanese woman with a fever and generalized skin eruptions was referred to our hospital in July 1999. At admission, her temperature was 38.9 degrees C, and she had fluctuating symptoms including erythema of the extremities, conjunctival hyperemia, strawberry tongue, and generalized skin eruptions, but lymphadenopathy was not verified. An initially elevated urine leukocyte count (more than 100 per high power field) later returned to normal range without antibiotic therapy. Adult Kawasaki disease was diagnosed on the basis of the above symptomology. Echocardiograph showed transient effusion in the pericardium. Using the Harada scoring system for treatment of Kawasaki disease, we gave the patient aspirin and did not administer intravenous immunoglobulin. The clinical course was uneventful, and on the day of discharge (day 22 after onset), the laboratory test results were nearly normal. Laboratory test results were negative for both Epstein-Barr virus and group A Streptococcus.
Hattori
Tomohiro
T
Department of Medicine, Division of Respirology, Nihon University School of Medicine, Tokyo.
Matsukawa
Yoshihiro
Y
Takei
Masami
M
Yamaguchi
Kenji
K
Yamazaki
Tetsuo
T
Sawada
Umihiko
U
Sawada
Shigemasa
S
Horie
Takashi
T
Ayusawa
Mamoru
M
Noto
Nobutaka
N
Harada
Kensuke
K
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D000914:Antibodies, Viral / Q000032:analysis; D001241:Aspirin / Q000627:therapeutic use; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D004452:Echocardiography; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology; D006801:Humans; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D013290:Streptococcal Infections / Q000175:diagnosis*; D013297:Streptococcus pyogenes / Q000276:immunology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000907:Antibodies, Bacterial; D000914:Antibodies, Viral; D004279:DNA, Viral; D001241:Aspirin