title: [Invasive bladder cancer recurrenced 5 years after complete response status by chemotherapy and radiotherapy: a case report].
abstract: A 72-year-old man had undergone trasucethral resection of bladder tumor (TUR-Bt) three times from 1990 to 1991 and he had been lost to follow with no recurrence from 1996, came to our hospital complaining of asymptomatic macrohematuria in May 1999. A bladder tumor existed around the right ureteral orifice with right hydronephrosis. MRI and TUR-Bt revealed that the cancer was transitional cell carcinoma (TCC) > small cell carcinoma, G3, pT3b. Because the patient insisted on bladder preservation, intra arterial chemotherapy with cisplatinum (CDDP) and epirubicin (EPI-adr) followed by radiotherapy with CDDP was performed. The treatment resulted in a clinical complete response (CR), and the bladder was preserved. In January 2004, an invasive bladder cancer recurred at the left lateral wall. This time, neoadjuvant intra-arterial chemotherapy with CDDP and EPI-adr, followed by radical cystectomy was performed. Histologically, the recurrent bladder cancer was TCC, G3, pT3b.
authors.affiliation: The Department of Urology, Minoh City Hospital.
authors.forename: Sinichirou
authors.initials: S
authors.lastname: Ito
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yokomizo
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Imazu
authors.forename: Hideki
authors.initials: H
authors.lastname: Sugao
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D015653:Cystectomy; D015251:Epirubicin / Q000008:administration & dosage; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012074:Remission Induction; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*
chemical_list: D015251:Epirubicin; D002945:Cisplatin