title: Highly efficient methods for the one-pot synthesis of beta-substituted enones.
abstract: A mild and practically-convenient one-pot procedure for the direct beta-substitution of enones has been developed using a conjugate addition-oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl chloride; alkyl- and aryl-substituted enones are delivered in good to excellent yields.
authors.affiliation: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, Scotland, UK G1 1XL. w.kerr@strath.ac.uk
authors.forename: William J
authors.initials: WJ
authors.lastname: Kerr
authors.forename: Colin M
authors.initials: CM
authors.lastname: Pearson
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Thurston
mesh_terms: D002625:Chemistry, Organic / Q000379:methods; D003300:Copper; D007202:Indicators and Reagents; D007659:Ketones / Q000138:chemical synthesis*; D010084:Oxidation-Reduction; D013441:Sulfinic Acids / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D007659:Ketones; D013441:Sulfinic Acids; D003300:Copper