Delayed postpartum hemorrhage--a rare clinical presentation of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: a case report.
Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are rare and closely related disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. Many risk factors have been reported including infection, cancer, pregnancy, a variety of drugs (e.g. anticancer drugs), and autoimmune diseases. The incidence of TTP-HUS is higher in females than in males, especially during pregnancy and the immediate postpartum period. Review of the literature reveals that delayed postpartum hemorrhage is a rare clinical presentation of TTP-HUS. We report a case of TTP-HUS with recurrent delayed postpartum hemorrhage and dismal outcome.
Chen
Yu-Chieh
YC
Departament of Obstetrics and Gynecology, Kaohsiung Medical University Chung-Ho Memorial Hospital, Taiwan.
Chen
Hung-Sheng
HS
Shen
Ching-Ju
CJ
Chang
Huei-Ming
HM
Tsai
Eing-Mei
EM
D000293:Adolescent; D005260:Female; D017359:HELLP Syndrome / Q000175:diagnosis; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D006473:Postpartum Hemorrhage / Q000209:etiology*; D011247:Pregnancy; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000209:etiology