title: Research opportunities and challenges in 2005.
abstract: OBJECTIVE
  Biomedical informatics practice and research have become so broad that I will comment on only three areas. These are the electronic health record; prospective population studies; and interactive publications.
  
  
  METHODS
  Review of the literature, Internet resources and material and reports generated by internal and external research projects.
  
  
  RESULTS
  Development of an electronic health record continues to be problematic in the U.S. A number of large-scale prospective cohort studies of normal populations are now actively occurring or in planning stage in a number of countries; these present special research opportunities in biomedical informatics. Although there are engineering challenges to the implementation of interactive publications, they have the potential to enhance understanding, learning, and memory of scientific and health concepts.
  
  
  CONCLUSIONS
  Three areas of bio-medical informatics challenge us and offer interesting and worthy research opportunities. These include the electronic health record, prospective cohort studies, and interactive publications.
authors.affiliation: National Library of Medicine, Bethesda, Maryland 20894, USA. lindberg@nlm.nih.gov
authors.forename: D A B
authors.initials: DA
authors.lastname: Lindberg
mesh_terms: D004059:Diffusion of Innovation; D005544:Forecasting; D023281:Genomics / Q000639:trends; D006801:Humans; D008490:Medical Informatics / Q000639:trends*; D016347:Medical Records Systems, Computerized / Q000592:standards / Q000639:trends*; D011446:Prospective Studies; D011643:Publishing / Q000639:trends*; D014481:United States; D018875:Vocabulary, Controlled