title: Incorporation of the sunscreen agent, octyl methoxycinnamate in a cellulosic fabric grafted with beta-cyclodextrin.
abstract: The aim of the study was to investigate the incorporation of the sunscreen agent, octyl methoxycinnamate into cyclodextrin cavities covalently bound to cloth fibres. Tencel, a cellulosic fabric, was grafted with beta-cyclodextrin molecules through reaction with monochlorotriazinyl-beta-cyclodextrin (beta-CDMCT). The finished and untreated textiles were soaked in water-methanol mixtures containing 2% (v/v) of sunscreen agent and subsequently subjected to several washing cycles. The unmodified and modified fabrics were characterized by UV spectrophotometry and thermogravimetric analysis. The level of octyl methoxycinnamate entrapped in the Tencel tissue was determined by high-performance liquid chromatography and was found to be much higher (0.0203%, w/w) for the textile functionalised with beta-CDMCT compared to the unmodified fabric (0.0025%, w/w). In addition, spectrophotometric assessment of UV transmission through the fabric samples using the Transpore test showed that the in vitro sun protection factor of the textile support was markedly enhanced (3.2-fold increase) by impregnation with octyl methoxycinnamate of the beta-CDMCT grafted textile. Hence, even after repeated washings, the beta-CD finished fabric exhibits higher sunscreen agent retention and photoprotective properties than the unmodified textile material.
authors.affiliation: Department of Pharmaceutical Sciences, University of Ferrara, via Fossato di Mortara, 44100 Ferrara, Italy. sls@unife.it
authors.forename: Santo
authors.initials: S
authors.lastname: Scalia
authors.forename: Rosanna
authors.initials: R
authors.lastname: Tursilli
authors.forename: Anna
authors.initials: A
authors.lastname: Bianchi
authors.forename: Pierandrea Lo
authors.initials: PL
authors.lastname: Nostro
authors.forename: Eugenio
authors.initials: E
authors.lastname: Bocci
authors.forename: Francesca
authors.initials: F
authors.lastname: Ridi
authors.forename: Piero
authors.initials: P
authors.lastname: Baglioni
mesh_terms: D002483:Cellulose, Oxidized / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D002934:Cinnamates / Q000737:chemistry*; D003020:Clothing; D013056:Spectrophotometry, Ultraviolet; D013473:Sunscreening Agents / Q000737:chemistry*; D013784:Textiles; D013818:Thermogravimetry; D014466:Ultraviolet Rays; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D002483:Cellulose, Oxidized; D002934:Cinnamates; D013473:Sunscreening Agents; D047392:beta-Cyclodextrins; C118580:octylmethoxycinnamate