Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment. Case report.
OBJECTIVE
We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance.


METHODS
Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection (ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX.


CONCLUSIONS
Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide.
Mendilcioglu
Inanc
I
Department of Obstetrics and Gynaecology, Akdeniz University, School of Medicine, Antalya, Turkey. imendilcioglu@yahoo.com
Ozcan
Mualla
M
Bagci
Gulseren
G
Simsek
Mehmet
M
Kursun
Sinan
S
Luleci
Guven
G
Taskin
Omur
O
D004200:Diseases in Twins / Q000000981:diagnostic imaging / Q000209:etiology / Q000235:genetics*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging / Q000209:etiology / Q000235:genetics*; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D011123:Polyploidy; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D020554:Sperm Injections, Intracytoplasmic; D014463:Ultrasonography