title: Optimization of factor analysis of the left ventricle in echocardiography for detecting wall motion abnormalities.
abstract: This study has tested solutions to optimize the ability of factor analysis of the left ventricle in echocardiography (FALVE) to detect segmental wall motion abnormalities automatically. On four- and two-chamber views of 38 patients, two factors (one flat curve and one curve describing the contraction-relaxation sequence) were extracted and associated factor images were combined to synthesize a parametric image (constant image in green, positive/negative values of the contraction-relaxation image in red/blue). The segments were graded on the visual and the parametric views. The impact of selecting a whole cardiac cycle, masking the left ventricle and realigning the image sequence on the results, was demonstrated. Systematic realignment had a positive impact, especially for patients with left bundle branch block or pacemaker. After alignment, for the entire population, the absolute concordance was 68.6% and the relative concordance (within one grade) was 99%. Thus, FALVE is promising for detecting segmental wall motion abnormalities.
authors.affiliation: INSERM, U678, CHU Pitié-Salpêtrière, Paris, France. benoit.diebold@egp.ap-hop-paris.fr
authors.forename: Benoît
authors.initials: B
authors.lastname: Diebold
authors.forename: Annie
authors.initials: A
authors.lastname: Delouche
authors.forename: Eric
authors.initials: E
authors.lastname: Abergel
authors.forename: Hanna
authors.initials: H
authors.lastname: Raffoul
authors.forename: Hervé
authors.initials: H
authors.lastname: Diebold
authors.forename: Frédérique
authors.initials: F
authors.lastname: Frouin
mesh_terms: D000328:Adult; D004452:Echocardiography / Q000379:methods*; D005163:Factor Analysis, Statistical; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*