title: World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of ectoparasiticides against myiasis causing parasites on ruminants.
abstract: These guidelines have been prepared to assist in the planning, conduct and interpretation of studies for the assessment of efficacy of ectoparasiticides against the myiasis causing parasites of ruminants. These guidelines specifically focus on larvicidal efficacy against myiasis causing flies. Information is provided on the selection of animals, dose determination and dose confirmation studies, field studies, record keeping and result interpretation. These guidelines advocate the use of pen facilities for dose determination and dose confirmation studies for defining therapeutic and persistent efficacy. These guidelines are also intended to assist investigators on how to conduct specific experiments, to provide specific information for registration authorities involved in the decision-making process, to assist in the approval and registration of new ectoparasiticides, and to facilitate the world-wide adoption of standard procedures.
authors.affiliation: Avcare Limited, Locked Bag 916, Canberra, 2601 ACT, Australia. peter.holdsworth@avcare.org.au
authors.forename: P A
authors.initials: PA
authors.lastname: Holdsworth
authors.forename: J
authors.initials: J
authors.lastname: Vercruysse
authors.forename: S
authors.initials: S
authors.lastname: Rehbein
authors.forename: R J
authors.initials: RJ
authors.lastname: Peter
authors.forename: C
authors.initials: C
authors.lastname: De Bruin
authors.forename: T
authors.initials: T
authors.lastname: Letonja
authors.forename: P
authors.initials: P
authors.lastname: Green
mesh_terms: D000818:Animals; D002417:Cattle; D004175:Diptera / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000592:standards*; D007814:Larva / Q000187:drug effects; D009198:Myiasis / Q000517:prevention & control / Q000662:veterinary*; D012107:Research Design / Q000592:standards; D012418:Ruminants / Q000469:parasitology*; D016896:Treatment Outcome
chemical_list: D007306:Insecticides