title: Exposure to loud noise and risk of acoustic neuroma.
abstract: Exposure to occupational loud noise has been previously identified as a possible risk factor for acoustic neuroma in only one relatively small (n = 86 cases) case-control study of men. The goal of the present study was to further examine the role of loud noise in acoustic neuroma etiology. In their population-based case-control study of both sexes conducted from 1999 to 2002 in Sweden, the authors compared reports on type and duration of occupational and nonoccupational loud noise exposure of 146 acoustic neuroma cases and 564 controls. Controls were randomly selected from the study base and were frequency matched on age, sex, and residential area. The authors found that individuals reporting loud noise exposure from any source were at increased risk for acoustic neuroma (odds ratio (OR) = 1.55, 95% confidence interval (CI): 1.04, 2.30). Exposure to loud noise from machines, power tools, and/or construction increased the risk for acoustic neuroma (OR = 1.79, 95% CI: 1.11, 2.89), as did exposure to loud music (OR = 2.25, 95% CI: 1.20, 4.23). The odds ratio for a latency period of 13 or more years since the first loud noise exposure from any source was 2.12 (95% CI: 1.40, 3.20). The findings of an increased risk of acoustic neuroma with loud noise exposure support previous research.
authors.affiliation: Division of Epidemiology, School of Public Health, The Ohio State University, Starling-Loving Hall Rm. A446, 320 West Tenth Avenue, Columbus, OH 43210, USA. colin.edwards@osumc.edu
authors.forename: Colin G
authors.initials: CG
authors.lastname: Edwards
authors.forename: Judith A
authors.initials: JA
authors.lastname: Schwartzbaum
authors.forename: Stefan
authors.initials: S
authors.lastname: Lönn
authors.forename: Anders
authors.initials: A
authors.lastname: Ahlbom
authors.forename: Maria
authors.initials: M
authors.lastname: Feychting
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000453:epidemiology / Q000209:etiology*; D009622:Noise / Q000009:adverse effects*; D009623:Noise, Occupational / Q000009:adverse effects; D016273:Occupational Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D016017:Odds Ratio; D012306:Risk; D018570:Risk Assessment; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology