Initial Candida dubliniensis isolate in Candida spp. positive haemocultures in Turkey between 2001 and 2004.
Candida dubliniensis which was first recognized in 1995 can be easily misidentified because of its phenotypic similarities with Candida albicans. In this study blood samples of patients from various departments of Ankara University Medical Faculty between January 2001-June 2004 were investigated for the distribution of Candida spp. and the presence of C. dubliniensis. Culture positive 67 fungi were included to the study. Phenotypic tests such as chlamydospore formation, colony morphology on Staib agar, growth at 45 degrees C, carbohydrate assimilation profiles were investigated for identification and differentiation of C. dubliniensis from C. albicans. To confirm the results polymerase chain reaction were used for suspected C. albicans and C. dubliniensis isolates. Among 38 germ tube and chlamydospore forming isolates, 37 of them were found as C. albicans and one as C. dubliniensis. The incidence of C. dubliniensis in our hospital is still low, this is the first C. dubliniensis isolate as an agent of candidaemia reported from Turkey.
Tekeli
Alper
A
Department of Microbiology and Clinical Microbiology, Ibn-I Sina Hospital, Ankara University School of Medicine, Turkey. tekeli@dialup.ankara.edu.tr
Akan
Ozay Arikan
OA
Koyuncu
Esra
E
Dolapci
Istar
I
Uysal
Sevil
S
D002175:Candida / Q000145:classification* / Q000302:isolation & purification / Q000502:physiology; D002177:Candidiasis / Q000382:microbiology*; D004271:DNA, Fungal / Q000235:genetics; D016469:Fungemia / Q000382:microbiology*; D006784:Hospitals, Teaching; D006801:Humans; D016133:Polymerase Chain Reaction; D014421:Turkey
D004271:DNA, Fungal