title: Combination of 2D sensitivity encoding and 2D partial fourier techniques for improved acceleration in 3D contrast-enhanced MR angiography.
abstract: Sensitivity encoding (SENSE) and partial Fourier (PF) techniques both reduce MRI acquisition time. Two-dimensional SENSE uses coil sensitivities to unfold aliasing in the phase/slice-encoding plane. One-dimensional PF and homodyne reconstruction are routinely applied in the frequency/phase-encoding plane to compensate for nonsampled k-space of the presumed real magnetization. Recently, a modified 3D elliptical centric acquisition was proposed to facilitate 2D-PF and homodyne reconstruction on an undersampled phase/slice-encoding plane. In this work we hypothesized that this 2D-PF technique can be combined with 2D-SENSE to achieve a greater acceleration factor than what each method can provide separately. Reconstruction of data whereby SENSE and PF are applied along the same axes is described. Contrast-enhanced MR angiography (CE-MRA) results from experiments using four receiver coils in phantom and volunteer studies are shown. In 11 volunteer studies, the SENSE-PF-homodyne technique using sevenfold acceleration (4x SENSE, 1.7x PF) consistently provided high-diagnostic-quality images with near 1-mm isotropic resolution in acquisition times of <20 s.
authors.affiliation: Magnetic Resonance Imaging Laboratory, Department of Radiology, Mayo Clinic College of Medicine, 200 1st Street S.W., Rochester, Minnesota 55905, USA.
authors.forename: Houchun H
authors.initials: HH
authors.lastname: Hu
authors.forename: Ananth J
authors.initials: AJ
authors.lastname: Madhuranthakam
authors.forename: David G
authors.initials: DG
authors.lastname: Kruger
authors.forename: James F
authors.initials: JF
authors.lastname: Glockner
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Riederer
mesh_terms: D003287:Contrast Media; D005583:Fourier Analysis; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007866:Leg / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA