title: Binding of alpha1-antichymotrypsin to the surface of lymphocytes--preliminary study.
abstract: OBJECTIVE
  The paper presents preliminary results of investigation of binding of alpha1-antichymotrypsin to the surface of peripheral blood lymphocytes.
  
  
  METHODS
  Pooled serum samples from healthy individuals served as source of alpha1-antichymotrypsin for isolation using chromatography. Binding of alpha1-antichymotrypsin to the surface of peripheral blood lymphocytes was measured by flow cytometry.
  
  
  RESULTS
  Even on native cells alpha1-antichymotrypsin may be detected. After incubation with isolated preparation the percentage of positive lymphocytes increased.
  
  
  CONCLUSIONS
  The presence of alpha1-antichymotrypsin on the surface of lymphocytes may imply its regulatory role during acute phase response and early immune response.
authors.affiliation: Department of Physiotherapy, Rheumatology and Rehabilitation, Karol Marcinkowski University of Medical Sciences, Poznań, Poland. magdula2811@poczta.onet.pl
authors.forename: M
authors.initials: M
authors.lastname: Sobieska
mesh_terms: D005434:Flow Cytometry; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D011485:Protein Binding; D015842:Serine Proteinase Inhibitors / Q000378:metabolism*; D000514:alpha 1-Antichymotrypsin / Q000378:metabolism*
chemical_list: D015842:Serine Proteinase Inhibitors; D000514:alpha 1-Antichymotrypsin