title: Photodynamic production of superoxide in vitro by altertoxins in the presence of reducing agents.
abstract: Superoxide production by the three 4,9-dihydroxyperylene-3,10-quinone fungal toxins, altertoxins I, II, and III, was stimulated on illumination with broad-spectrum light. As determined previously for cercosporin, superoxide production by illuminated altertoxins was increased by the addition of the reducing substances ergothioneine or urate; ascorbate also effectively increased superoxide production. Illuminated urate alone engendered some superoxide production.
authors.affiliation: Department of Biology, The Johns Hopkins University, Baltimore, Maryland 21218, and Division of Contaminants Chemistry, Food and Drug Administration, Washington, DC 20204.
authors.forename: P E
authors.initials: PE
authors.lastname: Hartman
authors.forename: C K
authors.initials: CK
authors.lastname: Suzuki
authors.forename: M E
authors.initials: ME
authors.lastname: Stack