Malignant hypercalcemia associated with a parathyroid macrocyst and the early genesis of a giant cell tumor.
Parathyroid cysts rarely cause primary hyperparathyroidism. In most cases, the resultant hypercalcemia is mild and detected before any significant skeletal disease develops. We report a patient with severe hypercalcemia, a synchronous brown tumor (osteitis fibrosa cystica) of the maxilla, and a large benign functional parathyroid cyst. The unusual patient presentation and management are described and illustrated. The pertinent literature is reviewed.
Oh
Anthony
A
Department of General Surgery and Surgical Oncology, Riverside Medical Center, Riverside, CA, USA.
Mojica
Pablo
P
Sullivan
Maureen
M
Tan
Dongfeng
D
Hicks
Wesley
W
Loree
Thom
T
Rigual
Nestor
N
D001707:Biopsy, Needle; D003560:Cysts / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis*; D007150:Immunohistochemistry; D008875:Middle Aged; D009367:Neoplasm Staging; D010279:Parathyroid Diseases / Q000473:pathology / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000473:pathology* / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods; D016896:Treatment Outcome