title: Wegener granulomatosis presenting as bilateral loss of vision.
abstract: We describe a man presenting with bilateral loss of vision secondary to a branch retinal artery occlusion and ischemic optic neuropathy, in turn related to underlying Wegener granulomatosis (WG). This case is unusual, because the simultaneous development of branch retinal artery occlusion and anterior ischemic optic neuropathy has, to our knowledge, not been reported in WG. Furthermore, only rarely does WG cause bilateral vision loss. The patient responded to immunosuppressive therapy and recovered sufficient vision to resume his vocation as a farmer.
authors.affiliation: Department of Medicine, University of Wisconsin Hospital, Madison, Wisconsin 53792, USA.
authors.forename: Vandana
authors.initials: V
authors.lastname: Khurma
authors.forename: Richard
authors.initials: R
authors.lastname: Appen
authors.forename: Mitchell D
authors.initials: MD
authors.lastname: Wolf
authors.forename: Karen E
authors.initials: KE
authors.lastname: Hansen
mesh_terms: D001766:Blindness / Q000188:drug therapy / Q000209:etiology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000150:complications / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D015356:Retinal Artery Occlusion / Q000150:complications / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone; D008775:Methylprednisolone; D008727:Methotrexate