title: Microbial transformation of esters of chlorinated carboxylic acids.
abstract: Two groups of compounds were selected for microbial transformation studies. In the first group were carboxylic acid esters having a fixed aromatic moiety and an increasing length of the alkyl component. Ethyl esters of chlorine-substituted carboxylic acids were in the second group. Microorganisms from environmental waters and a pure culture of Pseudomonas putida U were used. The bacterial populations were monitored by plate counts, and disappearance of the parent compound was followed by gas-liquid chromatography as a function of time. The products of microbial hydrolysis were the respective carboxylic acids. Octanol-water partition coefficients (K(ow)) for the compounds were measured. These values spanned three orders of magnitude, whereas microbial transformation rate constants (k(b)) varied only 50-fold. The microbial rate constants of the carboxylic acid esters with a fixed aromatic moiety increased with an increasing length of alkyl substituents. The regression coefficient for the linear relationships between log k(b) and log K(ow) was high for group 1 compounds, indicating that these parameters correlated well. The regression coefficient for the linear relationships for group 2 compounds, however, was low, indicating that these parameters correlated poorly.
authors.affiliation: Environmental Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30613.
authors.forename: D F
authors.initials: DF
authors.lastname: Paris
authors.forename: N L
authors.initials: NL
authors.lastname: Wolfe
authors.forename: W C
authors.initials: WC
authors.lastname: Steen