title: Descemet's membrane detachment after cataract extraction.
abstract: BACKGROUND
  Descemet's membrane detachment is a rare but potentially serious complication of intraocular surgery, most commonly cataract extraction. Small Descemet's membrane detachments typically resolve with topical medical therapy; however, larger detachments require surgical intervention. The most common surgical procedure is a gas-fluid exchange with 20% sulfur hexafluoride (SF6) or 14% perfluropropane (C3F8), which is typically performed at the biomicroscope and is nontoxic to the endothelium.
  
  
  METHODS
  A 77-year-old man underwent phacoemulsification with a posterior chamber lens implantation by clear corneal incision in the left eye. Visual acuity was 20/40 in the left eye 1 month postoperatively with persistent corneal edema. Visual acuity continued to deteriorate to counting fingers (CF), despite the use of topical hyperosmotics and steroids. At 2 months, a scrolled Descemet's membrane detachment was present from the incision site to the central cornea causing extensive edema. Anterior chamber injection of 14% C3F8 successfully reattached Descemet's membrane. Six weeks after surgery, the gas bubble had resolved, the central cornea was clear, and a curvilinear scar was present from 5:00 to 11:00. Visual acuity remained at CF owing to anterior capsular fibrosis. Anterior YAG capsulotomy improved the vision to 20/40.
  
  
  CONCLUSIONS
  Descemet's membrane detachment can have a devastating effect on vision. Timely management is imperative to preserve vision. This case shows the successful repair of Descemet's membrane detachment with 14% C3F8 after unsuccessful topical treatment.
authors.affiliation: VA Medical Center, Manchester, New Hampshire. jessicalynpotter@yahoo.com
authors.forename: Jessica
authors.initials: J
authors.lastname: Potter
authors.forename: Nadia
authors.initials: N
authors.lastname: Zalatimo
mesh_terms: D000368:Aged; D000867:Anterior Chamber; D002387:Cataract Extraction / Q000009:adverse effects*; D003316:Corneal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003886:Descemet Membrane / Q000473:pathology*; D005466:Fluorocarbons / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D011183:Postoperative Complications
chemical_list: D005466:Fluorocarbons; C042852:perflutren