[Chronic sinusitis therapy with antibiotics (axetyl cefuroxym, clarithromycin) and steroid (prednisone)].
We started therapy sinusitis of our patients with antibiotics cefuroxime axetil (Zinnat, GSK), clarithromycin (Klacid Uno, Abbott) and orally given steroid-prednisone in one group (A+S) 56 patients. Second group of 60 patients were cured only with antibiotics (A). We compare effects of this therapy. There were 50% totally cured patients in the first group (A+S) and 46.6% cured in the second group. Percentage totally cured patients with (A+S) is 3.4% better that cured only with antibiotics in the same time. It is statistically important. We present benefits for patients who were operated in the next step. Post therapy with the use of antibiotics and steroids there were less bleeding from the mucosal membrane, and there was no edema. It is a good method of therapy if patients have no contraindications.
Remer
Marek
M
S.P.Sz.W. w Zamościu, Oddział Laryngologii z Chirurgia Szczekowo-Twarzowa. remery@interia.pl
Polberg
Krzysztof
K
Obszańska
Bogusława
B
Klatka
Janusz
J
D000890:Anti-Infective Agents / Q000008:administration & dosage; D002444:Cefuroxime / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002908:Chronic Disease; D017291:Clarithromycin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D011241:Prednisone / Q000008:administration & dosage*; D012852:Sinusitis / Q000188:drug therapy*; D016896:Treatment Outcome
D000890:Anti-Infective Agents; D017291:Clarithromycin; D002444:Cefuroxime; D011241:Prednisone; C040738:cefuroxime axetil