title: [Disseminated fusariosis by Fusarium oxysporum in an adult patient with acute myeloid leukemia and severe febrile neutropenia].
abstract: We report the first case of disseminated fusariosis in an adult patient in Chile, with a hematologic neoplasia and chemotherapy that evolved with febrile prolonged neutropenia, refractory, treated with wide spectrum antibiotics and that developed a systemic infection with sinusal, cutaneous and pulmonary compromise by Fusarium oxysporum. He was refractory to antifungal treatment with amphotericin B deoxycholate and caspofungin that were administered in a sequential schedule. The fatal outcome of this patient was associated to persistent neutropenia and infection caused by a filamentous fungus usually resistant to antifungal therapy.
authors.affiliation: Infectología, Clínica Dávila. roc0107@yahoo.com
authors.forename: Roberto
authors.initials: R
authors.lastname: Olivares
authors.forename: Jorge
authors.initials: J
authors.lastname: Alfaro
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Díaz
authors.forename: Luis
authors.initials: L
authors.lastname: Thompson
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D005670:Fusarium; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000188:drug therapy; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000150:complications* / Q000188:drug therapy; D012720:Severity of Illness Index
chemical_list: D000935:Antifungal Agents