title: Acute central serous chorioretinopathy and fundus autofluorescence.
abstract: OBJECTIVE
  To describe fundus autofluorescence (FAF) in a series of patients with acute central serous chorioretinopathy (CSC).
  
  
  METHODS
  Nine eyes of six patients with acute CSC were evaluated with fluorescein angiography (FA) and FAF imaging to evaluate the nature of the focal retinal pigment epithelial (RPE) leak evident with FA.
  
  
  RESULTS
  All nine eyes in this series demonstrated hypo-autofluorescence corresponding precisely to the site of the focal RPE leak seen on FA.
  
  
  CONCLUSIONS
  In this group of patients, the acute focal RPE leaks seen with FA corresponded precisely to an area of hypo-autofluorescence imaged with FAF. This observation supports the concept that a mechanical defect or absence of the RPE accounts for the leakage from the inner choroid to the sub-neurosensory space in CSC. FAF is also a useful noninvasive diagnostic adjunct to identify the focal RPE leak in patients with acute CSC.
authors.affiliation: The LuEsther T. Mertz Retina Research Center of Manhattan Eye, Ear and Throat Hospital, New York, NY 10021, USA.
authors.forename: Chiara M
authors.initials: CM
authors.lastname: Eandi
authors.forename: Michael
authors.initials: M
authors.lastname: Ober
authors.forename: Reza
authors.initials: R
authors.lastname: Iranmanesh
authors.forename: Enrico
authors.initials: E
authors.lastname: Peiretti
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Yannuzzi
mesh_terms: D000208:Acute Disease; D000328:Adult; D002199:Capillary Permeability; D002829:Choroid / Q000098:blood supply; D015862:Choroid Diseases / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005453:Fluorescence; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000503:physiopathology