Atypical pyoderma gangrenosum as a manifestation of childhood acute lymphoblastic leukemia.
Pyoderma gangrenosum is a neutrophilic dermatosis that may occur idiopathically or in association with various systemic diseases and malignancy. Although the association of this entity with myeloid malignancies is well known, its association with lymphoid malignancy is extremely rare. We describe atypical pyoderma gangrenosum in association with acute lymphoblastic leukemia in a 2-year-old child, an occurrence not reported before.
Bakhshi
Sameer
S
Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India. sambakh@hotmail.com
Sethuraman
Gomathy
G
Singh
Manoj K
MK
Arya
Laxman Singh
LS
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001215:Asparaginase / Q000627:therapeutic use; D001707:Biopsy, Needle; D002675:Child, Preschool; D003630:Daunorubicin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014750:Vincristine; D001215:Asparaginase; D011241:Prednisone; D003630:Daunorubicin