Physical and biological characterizations of a novel multiphase anodic spark deposition coating to enhance implant osseointegration.
The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark-treated materials, with values higher than machined titanium. The results suggest that the BioSpark treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.
Giordano
Carmen
C
Department of Chemistry, Materials and Chemical Engineering G.Natta', Polytechnic of Milan, Via Mancinelli, 7, Milan, Italy. carmen.giordano@polimi.it
Chiesa
Roberto
R
Sandrini
Enrico
E
Cigada
Alberto
A
Giavaresi
Gianluca
G
Fini
Milena
M
Giardino
Roberto
R
D001842:Bone and Bones; D002448:Cell Adhesion; D002460:Cell Line; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration; D019736:Prostheses and Implants; D014961:X-Ray Diffraction