Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems.
The in vitro stability of archaeosomes made from novel synthetic membrane-spanning tetraether lipids was evaluated in conditions mimicking those of oral route application in terms of bile salts, serum and low pH..
Benvegnu
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ENSCR UMR CNRS 6052, Laboratoire Synthèses et Activations de Biomolécules, Institut de Chimie de Rennes, Avenue du Général Leclerc, 35700, Rennes, France. Thierry.Benvegnu@ensc_rennes.fr
Réthoré
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G
Brard
M
M
Richter
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W
Plusquellec
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D
D000284:Administration, Oral; D016503:Drug Delivery Systems; D004986:Ether / Q000737:chemistry*; D008055:Lipids / Q000138:chemical synthesis / Q000737:chemistry*; D008854:Microscopy, Electron; D015394:Molecular Structure
D008055:Lipids; D004986:Ether