title: [Resistance of Mycobacterium tuberculosis in a four-year period in a Madrid hospital].
abstract: Tuberculosis is considered a serious public health problem. Some factors, such as HIV infection and immigration, have had a major impact on the epidemiology of this illness in Spain. The problem has worsened in recent years due to the dissemination of multiresistant strains. Therefore, a periodic surveillance should be established with respect to the incidence and the resistances observed. In this study we collect M. tuberculosis isolates carried out in the years 2001, 2002, 2003 and 2004, and their susceptibility characteristics in patients from Area 2 in Madrid. To evaluate the isolates' susceptibilities, the MGIT 960 system was used. Of a total of 244 isolates, 15.2% were resistant to at least one antibiotic (different to streptomycin), and 29.9% of the isolates were obtained in samples from immigrant patients. In addition, the immigrant population affected showed a greater percentage of resistances (p <0.01) and a younger mean age (p <0.01) than the indigenous population.
authors.affiliation: Servicio de Microbiología y Parasitología, Hospital Universitario La Princesa, Madrid, España.
authors.forename: E
authors.initials: E
authors.lastname: Aznar
authors.forename: D
authors.initials: D
authors.lastname: Domingo
authors.forename: S
authors.initials: S
authors.lastname: Abanades
authors.forename: E
authors.initials: E
authors.lastname: García-Peñuela
authors.forename: M
authors.initials: M
authors.lastname: López-Brea
mesh_terms: D000328:Adult; D002648:Child; D024881:Drug Resistance, Bacterial; D015658:HIV Infections / Q000382:microbiology; D006786:Hospitals, Urban; D006801:Humans; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D013030:Spain; D013997:Time Factors; D014171:Transients and Migrants; D014504:Urban Health