title: Quantifying regional right ventricular function in tetralogy of Fallot.
abstract: Right ventricular (RV) function is notoriously difficult to quantify. Patients with tetralogy of Fallot (TOF) have decreased systolic performance. We measure regional RV performance using MRI with 1-dimensional myocardial tissue tagging. By tagging cine-MRI in two views, we measured regional shortening in 12 regions throughout the RV. We image 32 pediatric patients: 21 normal patients and 11 patients with repaired TOF. We establish a normal range for each RV region. TOF patients have decreased shortening on a region-by-region basis. We conclude that regional RV performance can be measured using this technique, and that decreased performance can be demonstrated in TOF patients.
authors.affiliation: Division of Cardiology, Children's Hospital Los Angeles, MS #34, 4650 Sunset Blvd., Los Angeles, CA 90027, USA. jmenteer@chla.usc.edu
authors.forename: Jondavid
authors.initials: J
authors.lastname: Menteer
authors.forename: Paul M
authors.initials: PM
authors.lastname: Weinberg
authors.forename: Mark A
authors.initials: MA
authors.lastname: Fogel
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D006348:Cardiac Surgical Procedures; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015986:Confounding Factors, Epidemiologic; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007091:Image Processing, Computer-Assisted; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009200:Myocardial Contraction; D011665:Pulmonary Valve Insufficiency / Q000503:physiopathology; D013318:Stroke Volume; D013771:Tetralogy of Fallot / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome; D016278:Ventricular Function, Right