Retroperitoneal fibrosis and c-ANCA positivity.
Retroperitoneal fibrosis (RPF) is an uncommon collagen vascular disease characterized by a chronic nonspecific inflammation of the retroperitoneum, which can entrap and obstruct retroperitoneal structures. Although obscure, an autoimmune-mediated or vasculitic etiology has been hypothesized. In the current report, a case of RPF associated with the presence of antibodies against proteinase III, which responded effectively to immunosuppressive therapy, is presented.
Mavragani
Clio P
CP
Department of Pathophysiology, School of Medicine, National University of Athens, Athens, Greece. MavraganiK@HSS.EDU
Voulgarelis
Michalis
M
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D012185:Retroperitoneal Fibrosis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D014657:Vasculitis / Q000150:complications / Q000628:therapy
D019268:Antibodies, Antineutrophil Cytoplasmic