title: [Application of HPLC/ELSD fingerprint and constellation graphical clustering method applied to evaluate the quality of Qingkailing injection].
abstract: OBJECTIVE
  To evaluate the quality of Qingkailing injections effectively, and to develop a credible method for the quality control of traditional Chinese medicine.
  
  
  METHODS
  Fingerprints of 18 Qingkailing injection samples from various manufacturers were obtained by HPLC/ELSD, and quality evaluation was performed by constellation graphical clustering method.
  
  
  RESULTS
  HPLC/ELSD and constellation graphical clustering method properly revealed the quality information apparently and accurately.
  
  
  CONCLUSIONS
  It was an apparent, credible and efficient method for quality evaluation of Chinese medicines.
authors.affiliation: Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
authors.forename: Shi-Kai
authors.initials: SK
authors.lastname: Yan
authors.forename: Wen-Feng
authors.initials: WF
authors.lastname: Xin
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Wang
authors.forename: Guo-An
authors.initials: GA
authors.lastname: Luo
authors.forename: Yi-Yu
authors.initials: YY
authors.lastname: Cheng
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D016000:Cluster Analysis; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D007267:Injections; D008027:Light; D008419:Materia Medica / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011786:Quality Control; D012542:Scattering, Radiation
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica; C504928:Qingkailing