[High doses statins administration causing rhabdomyolysis: case report].
Rhabdomyolysis has been the theme in medical literature for the last fifty years. In these last decades, with statins being used in primary and secondary cardiovascular prevention events, this theme returns and statins are now pointed as the trigger to this almost always fatal complication. Rhabdomyolysis due to statins administration occurs mainly in association with other drugs. Our case reports on a patient with fatal statin-induced rhabdomyolysis whose medical history included diffuse atherosclerotic disease.
Gama
Mirnaluci P Ribeiro
MP
Departamento de Medicina Interna, Faculdade Evangélica do Paraná, Hospital Universitário Evangélico de Curitiba, Curitiba, RS. m.gama@sul.com.br
Pellegrinello
Silviane
S
Alonso
Sheyla Santos Quelle
SS
Coelho
Juliana Filus
JF
Martins
Caroline F Luz
CF
Biagini
Gleyne Lopes Kujew
GL
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D001161:Arteriosclerosis / Q000188:drug therapy; D004347:Drug Interactions; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D019821:Simvastatin / Q000009:adverse effects* / Q000627:therapeutic use
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019821:Simvastatin