title: Pustular calicivirus dermatitis on the abdomen of two cats following routine ovariectomy.
abstract: An unusual form of calicivirus dermatitis is described in two cats. Two fully vaccinated cats were re-admitted for anorexia and depression following routine ovariectomy. Signs of upper respiratory disease were not present. One cat subsequently showed painful necrosis of the incision wound, the other one developed dyspnoea with pleural effusion and discrete tongue ulcers. Intact pustular lesions confined to the surgically prepared abdomen appeared in both cats, respectively, on days 11 and 9. The histopathological diagnosis was panepidermal pustulosis and necrotizing dermatitis. Positive immunohistochemical staining consistent with feline calicivirus antigen was detected in epithelial cells within pustular lesions. The cats were treated with antibiotics and ketoprofen. The cat with progressive dyspnoea was euthanized. The clinical signs in the other cat rapidly and completely resolved following glucocorticoid therapy. It is hypothesized that the reported cases may represent a distinct calicivirus-induced pustular dermatitis following ovariectomy.
authors.affiliation: Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. jan.declercq.vet@skynet.be
authors.forename: J
authors.initials: J
authors.lastname: Declercq
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use; D017250:Caliciviridae Infections / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D017927:Calicivirus, Feline / Q000302:isolation & purification*; D002371:Cat Diseases / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D002415:Cats; D003872:Dermatitis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D007150:Immunohistochemistry / Q000662:veterinary; D010052:Ovariectomy / Q000009:adverse effects / Q000662:veterinary*; D017193:Skin Diseases, Viral / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000662:veterinary*
chemical_list: D000998:Antiviral Agents; D005938:Glucocorticoids