Laparoscopic ovarian transposition to preserve ovarian function before pelvic radiation and chemotherapy in a young patient with rectal cancer.
BACKGROUND
Ovarian transposition is a surgical maneuver used to protect ovarian function before delivery of gonadocidal doses of radiation therapy. Ovarian transposition has been performed in patients whose treatment includes pelvic radiotherapy as a part of management for Hodgkin's disease and other gynecologic malignancies.


METHODS
Laparoscopic ovarian transposition was performed on a 28-year-old female with rectal cancer. At 13-month follow-up from completion of chemoradiation treatments, normal menstrual cycles at regular monthly intervals are reported. FSH, LH, and progesterone levels obtained during the second half of menstrual cycles were within normal ranges.


CONCLUSIONS
Ovarian transposition is an effective surgical procedure for preserving ovarian function in patients at risk of radiotherapy-induced ovarian failure. Laparoscopic techniques can be used to move the ovaries outside of the radiation portal. Consideration should be given for ovarian transposition for other abdominal and pelvic malignancies before onset of radiation treatments in patients who desire preservation of ovarian function.
Farber
Leonard A
LA
Radiation Oncology, Long Island Radiation Therapy/Nassau Radiologic Group, New York, NY, USA.
Ames
John W
JW
Rush
Stephen
S
Gal
David
D
D000328:Adult; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control*; D010053:Ovary / Q000503:physiopathology* / Q000637:transplantation*; D010388:Pelvis / Q000528:radiation effects; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D016042:Transplantation, Heterotopic