title: Autonomic features in cluster headache. Exploratory factor analysis.
abstract: The objective is to identify the pathogenesis of each autonomic manifestation in cluster headache (CH). Through a deductive statistics method (factor analysis) we analysed the type of autonomic symptoms reported by 157 CH patients. Three principal components were identified in the analysis: parasympathetic activation (lacrimation, conjunctival injection and rhinorrhoea), sympathetic defect (miosis and ptosis) and parasympathetic mediated effect (nasal congestion, eyelid oedema and forehead sweating). This work suggests that there are three different mechanisms underlying autonomic manifestations in CH.
authors.affiliation: Centro de Estudos Egas Moniz, Instituto de Medicina Molecular, Lisbon Faculty of Medicine, Hospital de Santa Maria, 1600 Lisbon, Portugal. rgilgouveia@netcabo.pt
authors.forename: Raquel Gil
authors.initials: RG
authors.lastname: Gouveia
authors.forename: Elsa
authors.initials: E
authors.lastname: Parreira
authors.forename: Isabel
authors.initials: I
authors.lastname: Pavão Martins
mesh_terms: D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000453:epidemiology / Q000503:physiopathology*; D001763:Blepharoptosis / Q000209:etiology / Q000503:physiopathology; D003027:Cluster Headache / Q000503:physiopathology*; D003228:Conjunctiva / Q000098:blood supply / Q000294:innervation / Q000503:physiopathology; D004487:Edema / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000209:etiology / Q000503:physiopathology; D007766:Lacrimal Apparatus Diseases / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015877:Miosis / Q000209:etiology / Q000503:physiopathology; D009297:Nasal Mucosa / Q000294:innervation / Q000378:metabolism / Q000503:physiopathology; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D015995:Prevalence; D025341:Principal Component Analysis; D013564:Sympathetic Nervous System / Q000503:physiopathology*