Measuring the induction or inhibition of apoptosis by HPV proteins.
Many viral proteins influence the cellular pathways that control cell proliferation and cell death. Some viral proteins trigger apoptotic cell death, and this may be important in host defense and viral spread. In other cases, viral proteins inhibit apoptosis. In this chapter, we will describe some of the methods that can be used to investigate the induction or inhibition of apoptosis by papillomavirus proteins.
Kowalczyk
Anna M
AM
Department of Biochemistry, School of Medical Sciences, University of Bristol, UK.
Roeder
Geraldine E
GE
Green
Katie
K
Stephens
David J
DJ
Gaston
Kevin
K
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002453:Cell Cycle; D016923:Cell Death; D002455:Cell Division; D002843:Chromatin / Q000502:physiology; D005434:Flow Cytometry; D017930:Genes, Reporter; D006367:HeLa Cells; D006801:Humans; D020287:In Situ Nick-End Labeling; D008856:Microscopy, Fluorescence; D009336:Necrosis; D027383:Papillomaviridae / Q000502:physiology*; D014764:Viral Proteins / Q000502:physiology*
D002843:Chromatin; D014764:Viral Proteins