Methyl transfer reaction from monomethyltin reagent under palladium(0) catalysis: a versatile method for labelling with carbon-11.
The 11C-monomethylstannate prepared from [11C]-methyl iodide and Lappert's stannylene, was subject to a palladium-mediated cross-coupling reaction with an aryl halide under ligand-free conditions, to afford easily purified 11C-methyl(hetero)arenes in high radiochemical yields.
Huiban
Mickaël
M
Groupe de Développements Méthodologiques en Tomographie par Emission de Positons, DRM-DSV, UMR CEA 2 FRE CNRS 2698, Université de Caen-Basse Normandie, Centre Cyceron, 15 Boulevard Becquerel, BP 5229, F-14074, Caen Cedex, France.
Huet
Aline
A
Barré
Louisa
L
Sobrio
Franck
F
Fouquet
Eric
E
Perrio
Cécile
C