title: [Microbiological investigations and studies of phagocytic activities of peripheral neutrophils during the treatment of parodontitis by Unimag].
abstract: During the treatment by Unimag (UN), quantity of microbes in the mouth cavity of patients with periodontitis (PD), significantly decreases in comparison with the patients treated by traditional scheme. That is due to direct and indirect influence of UN on the pathogenic microorganisms. During the treatment of patients with PD by UN, quantity of Gram-negative microbes gradually decreases and their substitution by Gram-positive microbes, typical for mouth cavity, takes place. On the background of the treatment by UN, phagocytic activity (PA) of polynuclear cells (PC) increases. In comparison with the patients treated by traditional scheme, increases both phagocytic number and number of active neutrophils. On 14-15 days after beginning of treatment of patients with PD by traditional scheme, PA of PC does not change significantly. Reduction of the microbial number in the mouth cavity and the active substitution of Gram-negative microbes by Gram-positive microorganisms during the treatment of patients with PD by UN, have prognostic importance and together with the reinforcement of PA of PC indicate to the improvement of the therapeutic effect and shortening of the duration of the treatment.
authors.forename: M G
authors.initials: MG
authors.lastname: Saralidze
authors.forename: L M
authors.initials: LM
authors.lastname: Dzhashi
authors.forename: T G
authors.initials: TG
authors.lastname: Tskitishvili
authors.forename: N N
authors.initials: NN
authors.lastname: Gogebashvili
authors.forename: B V
authors.initials: BV
authors.lastname: Surguladze
mesh_terms: D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use; D005260:Female; D052203:Ferrosoferric Oxide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000378:metabolism* / Q000648:ultrastructure*; D010510:Periodontal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D010586:Phagocytes / Q000378:metabolism* / Q000648:ultrastructure*
chemical_list: D018712:Analgesics, Non-Narcotic; D052203:Ferrosoferric Oxide; D004121:Dimethyl Sulfoxide