title: A case of systemic lupus erythematosus complicated by alveolar hemorrhage and cytomegalovirus colitis.
abstract: We report a rare case of systemic lupus erythematosus (SLE) complicated by alveolar hemorrhage and cytomegalovirus (CMV) colitis. Despite the successful treatment of lupus nephritis by steroid pulse therapy, the patient developed an acute alveolar hemorrhage 2 months later. Cyclophosphamide pulse therapy ameliorated the hemorrhage. One month later, she suddenly developed melena secondary to CMV colitis. Antiviral therapy was successful. We emphasize the importance of timely and precise differential diagnosis for successful management of complicated SLE.
authors.affiliation: 30-1 Oyaguchi Kami-machi, Itabashi-ku, Tokyo, 173-8610, Japan. numtakei@med.nihon-u.ac.jp
authors.forename: Masami
authors.initials: M
authors.lastname: Takei
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamakami
authors.forename: Ko
authors.initials: K
authors.lastname: Mitamura
authors.forename: Noboru
authors.initials: N
authors.lastname: Kitamura
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Matsukawa
authors.forename: Shigemasa
authors.initials: S
authors.lastname: Sawada
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003092:Colitis / Q000150:complications* / Q000473:pathology; D003106:Colon / Q000473:pathology; D003113:Colonoscopy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000000981:diagnostic imaging; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D011650:Pulmonary Alveoli; D011859:Radiography; D016896:Treatment Outcome; D005719:gamma-Globulins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D005719:gamma-Globulins; D003520:Cyclophosphamide; D015774:Ganciclovir