title: Separation of d-(+)-Nicotine from a Racemic Mixture by Stereospecific Degradation of the l-(-) Isomer with Pseudomonas putida.
abstract: Incubation of racemic mixtures of dl-(+/-)-nicotine with Pseudomonas putida resulted in a complete stereoselective degradation of the l-(-) isomer. Unnatural d-(+)-nicotine, which is of pharmacological interest for stereochemical studies of various nicotine-responsive systems, was not affected by the bacterium and was recovered by extraction.
authors.affiliation: Litron Laboratories, Ltd., Rochester, New York 14620.
authors.forename: M C
authors.initials: MC
authors.lastname: Detraglia
authors.forename: A M
authors.initials: AM
authors.lastname: Tometsko