title: Possible spontaneous regression of a metastatic lesion of keratoacanthoma-like squamous cell carcinoma in a regional lymph node.
abstract: We report herein a case of keratoacanthoma-like squamous cell carcinoma in an 82-year-old male that showed regional lymph node metastasis followed by self-regression of the metastatic lesion. This case is consistent with the previously reported observation that tumors compatible with the clinical features of keratoacanthoma may have malignant biological potential, however, it also demonstrates that even metastatic lesions may exhibit self-regression similar to that observed for primary lesions. Despite the view that keratoacanthoma-like squamous cell carcinoma may represent a variant of squamous cell carcinoma, occasionally it undergoes a unique clinical course.
authors.affiliation: Division of Dermatology and Plastic Surgery, Department of Sensory Medicine, Akita University School of Medicine, Akita, Japan.
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Ansai
authors.forename: Motomu
authors.initials: M
authors.lastname: Manabe
mesh_terms: D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D006801:Humans; D007636:Keratoacanthoma / Q000473:pathology*; D008297:Male; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*