title: Haloperoxidases: Enzymatic Synthesis of alpha,beta-Halohydrins from Gaseous Alkenes.
abstract: The enzymatic synthesis of alpha,beta-halohydrins from gaseous alkenes is described. The enzymatic reaction required an alkene, a halide ion, dilute hydrogen peroxide, and a haloperoxidase enzyme. A wide range of gaseous alkenes were suitable for this reaction, including those containing isolated, conjugated, and cumulative carbon-carbon double bonds. Chlorohydrins, bromohydrins, and iodohydrins could be formed. The combining of this enzymatic synthesis with a previously described enzymatic synthesis of epoxides from alpha,beta-halohydrins provides an alternate pathway, other than the well-known enzymatic direct epoxidation pathway, from alkene to an epoxide.
authors.affiliation: Cetus Corporation, Berkeley, California 94710.
authors.forename: J
authors.initials: J
authors.lastname: Geigert
authors.forename: S L
authors.initials: SL
authors.lastname: Neidleman
authors.forename: D J
authors.initials: DJ
authors.lastname: Dalietos
authors.forename: S K
authors.initials: SK
authors.lastname: Dewitt