[Bleomycin induced flagellate erythema].
Bleomycin is an antibiotic with antineoplastic pro prieties. It is used in the traitement of many syndromes. The cutaneous toxicity of bleomycin includes many alteration. We report a case of flagellate erythema following the administration of bleomycin in a 57-year-old women with Kaposi sarcoma. She developped linear lesions 6 days after the first dose of bleomycin. Flagellate erythema is a specific reaction to bleomycin therapy wich occurs in susceptible individuals independently of dose, route of administration and type of malignant disease treated. Its occurs in 10 to 35% of the treated patients.
Mseddi
M
M
Service de Dermatologie CHU H. Chaker, Sfax, Tunisie.
Hadj Taieb
H
H
Abdelmaksoud
W
W
Khemakhem
M
M
Turki
H
H
Masmoudi
A
A
Zahaf
A
A
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects*; D004890:Erythema / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000188:drug therapy
D000964:Antimetabolites, Antineoplastic; D001761:Bleomycin