[New charge-deficient agmatine analogs].
N,N'-Di-Boc-N"-triflylguanidine was demonstrated to be an efficient guanidinylation reagent for O-substituted hydroxylamines. N-(3-Aminooxypropyl)- and N-(3-aminopropoxy)guanidines, previously unknown isosteric and charge-deficient agmatine analogues, have been synthesized. The possibilities of using these compounds in studying polyamine metabolism are discussed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 6; see also http://www.maik.ru.
Simonian
A R
AR
Grigorenko
N A
NA
Vepsalainen
J
J
Khomutov
A R
AR
D000376:Agmatine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
D000376:Agmatine