title: [Meconium as a new biological material for detecting intrauterine exposure to toxic substances].
abstract: The use of licit and illicit drugs and exposure to other xenobiotic agents during pregnancy is common. These substances are known to have adverse effects on the pregnancy and fetus; however information on fetal exposure is sparse due to the lack of an appropriate measure of exposure. Meconium analysis is a new method for identifying in utero exposure of infants to a number of illicit and legal drugs, alcohol, nicotine, heavy metals, pesticides, congenital infections. It's testing is non-invasive, highly accurate and able to detect prior exposure in utero during 12-40 weeks of gestation. This has implications for toxicology to develop improved methods to identify exposed infants.
authors.affiliation: Katedra i Zakład Biochemii i Chemii Klinicznej, Akademia Medyczna w Warszawie. tomasz@artibus.pl
authors.forename: Barbara
authors.initials: B
authors.lastname: Lisowska-Myjak
mesh_terms: D015198:Designer Drugs / Q000009:adverse effects; D005260:Female; D006266:Health Education / Q000592:standards; D006801:Humans; D013287:Illicit Drugs / Q000009:adverse effects; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000139:chemically induced / Q000175:diagnosis; D008429:Maternal Welfare; D008470:Meconium / Q000737:chemistry; D009035:Mothers / Q000193:education; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000175:diagnosis; D015262:Xenobiotics / Q000009:adverse effects*
chemical_list: D015198:Designer Drugs; D013287:Illicit Drugs; D015262:Xenobiotics