title: Effects of cytomegalovirus (CMV) related deafness on pediatric cochlear implant outcomes.
abstract: OBJECTIVE
  Human cytomegalovirus (CMV) is a commonly recognized viral cause of perinatal sensorineural hearing loss. CMV-infected infants are also at risk for developmental neurological deficits. This retrospective study assesses the impact of CMV-induced deafness on pediatric cochlear implant outcomes.
  
  
  METHODS
  Thirteen patients from the Johns Hopkins pediatric cochlear implant database were identified with CMV-related deafness. A retrospective review of the medical records of the Johns Hopkins Hospital was performed.
  
  
  RESULTS
  The mean age at implantation was 5.6 years. Follow-up audiometric data ranged from 6 to 48 months postoperatively. Mean speech perception scores were 4.5 (out of 6) following implantation.
  
  
  CONCLUSIONS
  We have shown that cochlear implants can provide useful speech comprehension to patients with CMV-related deafness. Speech recognition scores were within the range established by our overall pediatric implant population.
  
  
  CONCLUSIONS
  This observation underscores the importance of a multidisciplinary rehabilitation program following implantation in these patients at risk for cognitive delay.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Lee
authors.forename: Lawrence
authors.initials: L
authors.lastname: Lustig
authors.forename: Margaret
authors.initials: M
authors.lastname: Sampson
authors.forename: Jill
authors.initials: J
authors.lastname: Chinnici
authors.forename: John K
authors.initials: JK
authors.lastname: Niparko
mesh_terms: D000914:Antibodies, Viral / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation / Q000295:instrumentation*; D003054:Cochlear Implants; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000821:virology; D003638:Deafness / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D013067:Speech Perception / Q000502:physiology; D013069:Speech Reception Threshold Test; D016896:Treatment Outcome
chemical_list: D000914:Antibodies, Viral