title: A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H.
abstract: We report a case of sporadic atypical hemolytic uremic syndrome (HUS) with a transient decrease in complement factor H. Referred for hemolysis and azotemia without diarrhea prodrome, this 31-month-old boy showed a decreased complement 3 (C3) and complement factor H (FH) level. However, the factor H gene (HF1) mutation was missing. After the hemolysis was controlled with plasma infusion, the C3 and FH levels recovered. The patient's renal function fully recovered and remained normal, and there was no recurrence of the HUS.
authors.affiliation: Department of Pediatrics, Eulji University School of Medicine, Daejeon, Korea. petercat67@empal.com
authors.forename: Hyewon
authors.initials: H
authors.lastname: Hahn
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Um
authors.forename: Young Seo
authors.initials: YS
authors.lastname: Park
authors.forename: Hae Il
authors.initials: HI
authors.lastname: Cheong
mesh_terms: D002675:Child, Preschool; D017242:Complement Factor H / Q000032:analysis*; D006463:Hemolytic-Uremic Syndrome / Q000097:blood* / Q000175:diagnosis; D006801:Humans; D008297:Male
chemical_list: D017242:Complement Factor H