title: Cancer of the nasal vestibule, nasal cavity and paranasal sinuses.
abstract: The usual clinical presentation of sinonasal tumours includes symptoms that are indistinguishable from inflammatory sinus disease, namely nasal airway obstruction, pain, and epistaxis. Abnormal V1 and/or V2 sensations are a strong indication of the possibility of tumour. Computed tomography is the most reliable and informative imaging tool for evaluating the cancers of the paranasal sinuses. Magnetic resonance imaging is essential for tumour mapping because of the excellent tissue characterisation and the possibility of differentiating between neoplasms and retained secretions. A wide variety of histologies may be encountered, although squamous cell carcinoma (SCCA) is the most common. Radiation is a common adjuvant to surgery. The response of sinonasal tract tumours to radiation therapy varies with the stage and histology of the tumour. Rehabilitation after surgical resection may be accomplished with prosthodontics or reconstructive flaps. Bony erosion of the orbital walls does not constitute an indication for orbital exenteration. Patients with tumour involvement of the skull base, either in the infratemporal fossa or at the fovea ethmoidalis and cribriform plate, should be considered for craniofacial resection. Management of these tumours requires a multimodal approach, involving surgery, radiation therapy and, increasingly in recent years, chemotherapy. Management should therefore be entrusted to multidisciplinary teams only.
authors.affiliation: ENT-HNS Department, CHR Citadelle, 4000 Liège, Belgium. daele@cybernet.be
authors.forename: J J
authors.initials: JJ
authors.lastname: Daele
authors.forename: V
authors.initials: V
authors.lastname: Vander Poorten
authors.forename: P
authors.initials: P
authors.lastname: Rombaux
authors.forename: M
authors.initials: M
authors.lastname: Hamoir
mesh_terms: D017024:Chemotherapy, Adjuvant; D006801:Humans; D008279:Magnetic Resonance Imaging; D009296:Nasal Cavity / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed