title: [Effect of tissue-type plasminogen activator and its inhibitor in haemostasis system function in norm and pathology].
abstract: The paper is dedicated to the study of structure and physiological functions of tissue type plasminogen activator and its inhibitor PAI-1, changes of these parametres in normal and pathology conditions. The interrelation of the coagulation and the fibrinolytic system during the range of pathologies was studied. It was demonstrated that simultaneous analysis of the coagulation and fibrinolytic systems analysis allow to diagnose the thrombotic complications.
authors.forename: Ie M
authors.initials: IeM
authors.lastname: Krasnobryzha
authors.forename: O M
authors.initials: OM
authors.lastname: Savchuk
authors.forename: T M
authors.initials: TM
authors.lastname: Platonova
authors.forename: H L
authors.initials: HL
authors.lastname: Volkov
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000378:metabolism*; D006487:Hemostasis; D006801:Humans; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D010959:Tissue Plasminogen Activator / Q000097:blood / Q000378:metabolism / Q000502:physiology*
chemical_list: D017395:Plasminogen Activator Inhibitor 1; D010959:Tissue Plasminogen Activator