Effect of a killer toxin of yeast on eucaryotic systems.
The Saccharomyces cerevisiae killer toxin KT 28, which inhibits sensitive yeasts, was shown to have no effect on several pathogenic fungi or on the protozoan Trichomonas vaginalis. At concentrations of about 0.1 mg/ml, a partial inhibition of the skin pathogenic fungi Trichophyton rubrum and Microsporum canis was observed at pH 6.5. No pharmacological activity was detected in various tests with several animal organs.
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Institut für Mikrobiologie und Weinforschung, Johannes Gutenberg-Universität Mainz, Postfach 3980, D-6500 Mainz, and Abteilungen Pharmakologie und Chemotherapie, Hoechst AG, Postfach 80 03 20, D-6230 Frankfurt 80, Federal Republic of Germany.
Radler
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Caspritz
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Hänel
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