title: Patients' recollections of therapeutic paralysis in the intensive care unit.
abstract: BACKGROUND
  Neuromuscular blocking agents used for therapeutic purposes, such as facilitating mechanical ventilation and relieving life-threatening agitation, paralyze patients but leave them fully conscious. Aggressive sedation or analgesia is necessary to reduce awareness, relieve fear, produce comfort, decrease anxiety, induce unconsciousness, and minimize possible complications such as posttraumatic stress syndrome. Little information is available on the extent to which patients experience awareness during therapeutic paralysis.
  
  
  OBJECTIVE
  To determine and describe the remembered experiences of critical care patients who were given neuromuscular blocking agents and sedatives and/or analgesics to facilitate mechanical ventilation, improve hemodynamic stability, and improve oxygenation.
  
  
  METHODS
  A phenomenological approach with in-depth interviews with 11 patients was used. Data were analyzed by using the constant comparative approach.
  
  
  RESULTS
  A total of 4 themes and 3 subthemes were identified. The first theme was back and forth between reality and the unreal, between life and death; the subtheme was having weird dreams. The second theme was loss of control; the 2 subthemes were (1) fighting or being tied down and (2) being scared. The third theme was almost dying, and the fourth theme was feeling cared for.
  
  
  CONCLUSIONS
  Patients can remember having both negative and positive experiences during neuromuscular blockade. Steps to improve the experiences of patients receiving neuromuscular blockers include improving assessment parameters, developing and using sedation/analgesia guidelines, and investing in quality improvement programs to provide assessment of awareness during therapeutic paralysis and follow-up and referral as necessary. Ways to decrease the use of neuromuscular blockers would also be useful.
authors.affiliation: WellStar Health System, Marietta, GA, USA.
authors.forename: Nancy
authors.initials: N
authors.lastname: Ballard
authors.forename: Lois
authors.initials: L
authors.lastname: Robley
authors.forename: Darcy
authors.initials: D
authors.lastname: Barrett
authors.forename: Danielle
authors.initials: D
authors.lastname: Fraser
authors.forename: Inocencia
authors.initials: I
authors.lastname: Mendoza
mesh_terms: D000328:Adult; D000368:Aged; D000698:Analgesia / Q000523:psychology; D001007:Anxiety / Q000523:psychology; D001364:Awareness / Q000187:drug effects; D016292:Procedural Sedation / Q000523:psychology; D003422:Critical Care / Q000379:methods*; D004325:Dreams / Q000523:psychology; D005260:Female; D006801:Humans; D007103:Immobilization / Q000379:methods / Q000523:psychology*; D007297:Inpatients / Q000523:psychology*; D007362:Intensive Care Units; D007407:Interviews as Topic / Q000379:methods; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000627:therapeutic use*; D010146:Pain / Q000517:prevention & control / Q000523:psychology
chemical_list: D009466:Neuromuscular Blocking Agents