title: Renal anemia aggravated by long-term parvovirus B19 and cytomegalovirus infection in a renal transplant patient: case report and evaluation of B19 seroprevalence in dialysis patients.
abstract: Due to viral replication in erythroid precursor cells, severe anemia represents a major complication of B19 infection. However, cytomegalovirus (CMV) is the leading cause of virus-induced complications with a significant impact on graft outcome of renal transplant patients. Herein, we present a long-term B19 infection in a 45-year-old female renal transplant patient, which aggravated the renal anemia associated with a concomitant CMV infection. Since no data were available on the seroprevalence of this virus in pretransplant patients, we determined the B19 serostatus of 90 dialyzed pretransplant adult subjects.
authors.affiliation: Institute of Medical Microbiology and Immunology, University of Bonn, Bonn, Germany.
authors.forename: M R
authors.initials: MR
authors.lastname: Becker
authors.forename: B
authors.initials: B
authors.lastname: Schneider
authors.forename: U
authors.initials: U
authors.lastname: Reber
authors.forename: U
authors.initials: U
authors.lastname: Pöge
authors.forename: B
authors.initials: B
authors.lastname: Klein
authors.forename: H U
authors.initials: HU
authors.lastname: Klehr
authors.forename: H
authors.initials: H
authors.lastname: Zhou
authors.forename: H P
authors.initials: HP
authors.lastname: Fischer
authors.forename: A M
authors.initials: AM
authors.lastname: Eis-Hübinger
mesh_terms: D000328:Adult; D000368:Aged; D000740:Anemia / Q000150:complications*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000150:complications* / Q000453:epidemiology; D016732:Parvovirus B19, Human / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D016036:Seroepidemiologic Studies
chemical_list: D007074:Immunoglobulin G