title: [Total antioxidant capacity of seminal plasma in fertile and infertile men].
abstract: OBJECTIVE
  To evaluate total antioxidant capacity (TAC) of seminal plasma in fertile and infertile men and understand the relation between seminal plasma TAC and male fertility.
  
  
  METHODS
  Two hundred and twenty-five infertile men were divided into 10 cases of obstructive azoospermic men, 42 cases of non-obstructive azoospermic men,20 cases of oligozoospermic men, 78 cases of asthenozoospermic men, 57 cases of oligoasthenozoospermic men, and 18 cases of normozoospermic men, then 28 fertile men were taken as the control. The seminal parameter analysis was performed by computer-assisted semen analysis (CASA) system. Seminal plasma TAC was measured using spectroscopic analysis.
  
  
  RESULTS
  Seminal plasma TAC were (1.71 +/- 1.33) U in obstructive azoospermic men, (12.73 +/- 9.44) U in non-obstructive azoospermic men, (10.85 +/- 6.64) U in oligozoospermic men, (13.88 +/- 8.24) U in asthenozoospermic men, (11.20 +/- 7.02) U in oligoasthenozoospermic men, (18.07 +/- 8.73) U in normozoospermic men, and (19.82 +/- 6.33) U in fertile men. There was no significant difference in TAC between normozoospermic men and fertile men (P > 0.05). Compared with fertile men, seminal plasma TAC in other infertile groups was significantly lower (P < 0.01). There were significantly made positive correlation between seminal plasma TAC and sperm density (r = 0.182, P < 0.05), as well as sperm with grade a (r = 0.150, P < 0.05).
  
  
  CONCLUSIONS
  Seminal plasma TAC is closely related to male fertility, and the decreased level of TAC in seminal plasma may be one of the causes of male infertility.
authors.affiliation: Department of Andrology, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
authors.forename: Yi-chao
authors.initials: YC
authors.lastname: Shi
authors.forename: Hui-min
authors.initials: HM
authors.lastname: Sun
authors.forename: Xue-jun
authors.initials: XJ
authors.lastname: Shang
authors.forename: Pei-yuan
authors.initials: PY
authors.lastname: Zhu
authors.forename: Yu-feng
authors.initials: YF
authors.lastname: Huang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005298:Fertility / Q000502:physiology*; D006801:Humans; D007248:Infertility, Male / Q000503:physiopathology*; D008297:Male; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species / Q000378:metabolism*; D012661:Semen / Q000737:chemistry*
chemical_list: D017382:Reactive Oxygen Species