Resistance training improves insulin signaling and action in skeletal muscle.
Resistance training can improve glucose transport in both normal and insulin-resistant skeletal muscle by enhancing the activation of the insulin signaling cascade and increasing GLUT-4 protein concentration. These training-induced alterations improve the quality of the skeletal muscle and can occur independent of significant increases in skeletal muscle mass.
Yaspelkis
Ben B
BB
Exercise Biochemistry Laboratory, Department of Kinesiology, College of Health and Human Development, California State University Northridge, CA 91330-8287, USA. ben.yaspelkis@csun.edu
D000818:Animals; D051275:Glucose Transporter Type 4 / Q000378:metabolism; D007328:Insulin / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000502:physiology; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D010805:Physical Conditioning, Animal / Q000502:physiology*; D011493:Protein Kinase C / Q000378:metabolism; D051381:Rats; D015398:Signal Transduction / Q000502:physiology*
D051275:Glucose Transporter Type 4; D007328:Insulin; D019869:Phosphatidylinositol 3-Kinases; D011493:Protein Kinase C