Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging.
We report here the synthesis and characterization of a new type of non-ionic blue fluorescent water-soluble chromophores specifically designed for two-photon absorption microscopy. The water solubility is induced by introduction of short oligo(ethylene glycol) monomethyl ether moieties. This work has led to low molecular weight dyes with efficient two-photon absorption cross sections and high fluorescence quantum yield in organic solvents as well as in aqueous solutions.
Hayek
Ali
A
Groupe des Matériaux Organiques, Institut de Physique et Chimie des Matériaux de Strasbourg, CNRS, 23 rue du Loess, F-67034, Strasbourg, France.
Bolze
Frédéric
F
Nicoud
Jean-François
JF
Baldeck
Patrice L
PL
Mély
Yves
Y
D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D008970:Molecular Weight; D017785:Photons; D011789:Quantum Theory; D012680:Sensitivity and Specificity; D012995:Solubility; D013050:Spectrometry, Fluorescence; D013267:Stilbenes / Q000138:chemical synthesis* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
C509721:4,4'-bis(3',4',5'-tridodecyloxystilbene-4-yl)biphenyl; D001713:Biphenyl Compounds; D005456:Fluorescent Dyes; D013267:Stilbenes; D014867:Water