title: Levetiracetam in a neonate with malignant migrating partial seizures.
abstract: This report describes the first neonatal case of "malignant migrating partial seizures in infancy" with a positive therapeutic response to levetiracetam. This patient is the youngest reported infant with this rare syndrome, and the report provides the first documentation on levetiracetam treatment in a neonatal patient. Treatment with levetiracetam improved both ictal and interictal status. This observation also highlights the need to consider and include malignant migrating partial seizures in the differential diagnosis of early neonatal seizure disorders, even during the first hours of life.
authors.affiliation: Neurologie Pédiatrique, Cliniques Universitaires Saint Luc (UCL), Brussels, Belgium.
authors.forename: Ghassan
authors.initials: G
authors.lastname: Hmaimess
authors.forename: Hazim
authors.initials: H
authors.lastname: Kadhim
authors.forename: Marie-Cécile
authors.initials: MC
authors.lastname: Nassogne
authors.forename: Christine
authors.initials: C
authors.lastname: Bonnier
authors.forename: Kenou
authors.initials: K
authors.lastname: van Rijckevorsel
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use*; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D000077287:Levetiracetam; D008297:Male; D010889:Piracetam / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D000077287:Levetiracetam; D010889:Piracetam