title: A case of pulmonary synovial sarcoma diagnosed with detection of chimera gene: imaging findings.
abstract: Pulmonary synovial sarcoma is a rare disease, and reports detailing clinicians' radiological findings are few. We report a case of a primary pulmonary synovial sarcoma in a 68-year-old woman. Chest CT revealed a well-defined and homogeneous oval mass measuring 3x2.5 cm in the left lower lobe in contact with the visceral pleura. No pleural effusion was evident. No calcification or fat component was detected. The tumor showed homogeneous hypointensity on both T1- and T2-weighted MR imaging. In this case, a lung metastasis could be excluded with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET), and the final diagnosis was histopathologically confirmed by the chimeric gene detection.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, Fukuoka Prefecture 812-8582, Japan. yymatsuo@radiol.med.kyushu-u.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsuo
authors.forename: Shuji
authors.initials: S
authors.lastname: Sakai
authors.forename: Hidetake
authors.initials: H
authors.lastname: Yabuuchi
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Soeda
authors.forename: Naoki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Okafuji
authors.forename: Kengo
authors.initials: K
authors.lastname: Yoshimitsu
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Koga
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yoshino
authors.forename: Yoshinao
authors.initials: Y
authors.lastname: Oda
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000235:genetics*; D046528:Chimerism; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000235:genetics; D008279:Magnetic Resonance Imaging; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D049268:Positron-Emission Tomography; D013584:Sarcoma, Synovial / Q000175:diagnosis* / Q000235:genetics
chemical_list: D014408:Biomarkers, Tumor; D015514:Oncogene Proteins, Fusion; C116512:SYT-SSX fusion protein; D019788:Fluorodeoxyglucose F18