title: Laparoscopic bilateral partial adrenalectomy for adrenocortical adenomas causing Cushing's syndrome: report of a case.
abstract: Laparoscopic total adrenalectomy has become a standard technique for small adrenal tumors; however, bilateral adrenalectomy results in postoperative adrenal insufficiency, necessitating lifelong steroid replacement. To preserve adrenocortical function in a 41-year-old woman with bilateral adrenocortical adenoma (BAA) causing Cushing's syndrome, we performed laparoscopic bilateral partial adrenalectomy. We based our preoperative diagnosis of bilateral adrenocortical tumors causing Cushing's syndrome on the results of endocrinological investigations and imaging findings. Thus, we performed lateral transperitoneal laparoscopic bilateral partial adrenalectomy, preserving the adrenal glands, which were normal. Pathological examination of both tumors confirmed the diagnosis of adrenocortical adenoma. The patient had no postoperative complications, and her adrenocortical function was normal without steroid replacement at her 10-month follow-up. This report shows that Cushing's syndrome resulting from bilateral adenomas can be effectively treated by laparoscopic bilateral partial adrenalectomy as a minimally invasive, adrenocortical-preserving operation.
authors.affiliation: Division of Organ Regeneration Surgery, Department of Surgery, School of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori 683-8504, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Inoue
authors.forename: Kiyosuke
authors.initials: K
authors.lastname: Ishiguro
authors.forename: Takako
authors.initials: T
authors.lastname: Suda
authors.forename: Norimasa
authors.initials: N
authors.lastname: Ito
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Yuji
authors.initials: Y
authors.lastname: Taniguchi
authors.forename: Shigetsugu
authors.initials: S
authors.lastname: Ohgi
mesh_terms: D000315:Adrenalectomy / Q000379:methods*; D018246:Adrenocortical Adenoma / Q000150:complications / Q000601:surgery*; D000328:Adult; D003480:Cushing Syndrome / Q000209:etiology*; D005260:Female; D006801:Humans; D010535:Laparoscopy