Cucurbitosides F-M, acylated phenolic glycosides from the seeds of Cucurbita pepo.
Eight new phenolic glycosides, cucurbitosides F-M (1-8), were isolated from the seeds of Cucurbita pepo. Their structures were elucidated as 4-(2-hydroxyethyl)phenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (1), 4-(2-hydroxyethyl)phenyl 5-O-(3-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (2), 4-(2-hydroxyethyl)phenyl 5-O-nicotinyl-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (3), 4-(2-hydroxyethyl)phenyl 5-O-(4-aminobenzoyl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (4), 4-(2-hydroxyethyl)-2-methoxyphenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (5), 4-(hydroxymethyl)phenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (6), 4-(hydroxymethyl)phenyl 5-O-nicotinyl-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (7), and 4-(hydroxymethyl)phenyl 5-O-(4-aminobenzoyl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (8) on the basis of various spectroscopic analyses and analyses of hydrolysis products.
Li
Wei
W
Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Koike
Kazuo
K
Tatsuzaki
Masaru
M
Koide
Atsushi
A
Nikaido
Tamotsu
T
D000107:Acetylation; D028464:Cucurbita / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification*; D012639:Seeds / Q000737:chemistry
D006027:Glycosides; D010636:Phenols