Human metapneumovirus-associated lower respiratory tract infections in korean infants and young children.
To define the role of human metapneumovirus (hMPV) in previously healthy Korean children, a retrospective study was done on 166 children with lower respiratory tract infections and on their stored nasal aspirates. The hMPV gene was detected by reverse transcriptase-polymerase chain reaction. Twenty-six of 166 individuals tested positive for hMPV. The clinical diagnoses of hMPV infection were pneumonia in 15 children and bronchiolitis in 11 children.
Kim
Yun-Kyung
YK
Department of Pediatrics, Korea University College of Medicine, Korea,
Lee
Hoan-Jong
HJ
D000293:Adolescent; D001990:Bronchiolitis, Viral / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007723:Korea / Q000453:epidemiology; D008297:Male; D029121:Metapneumovirus / Q000235:genetics / Q000302:isolation & purification*; D018184:Paramyxoviridae Infections / Q000453:epidemiology* / Q000821:virology; D010802:Phylogeny; D011024:Pneumonia, Viral / Q000453:epidemiology* / Q000821:virology; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012621:Seasons