Illustration of dynamic changes in Alzheimer pathology: from mild cognitive impairment to terminal stage.
It is quite important to examine the neuropathology of large numbers of brains from non-demented as well as demented subjects to elucidate the pathogenesis of dementia. Such a study, "power neuropathology" reveals the temporal profile of the disease, and results in the development of the treatment and the prevention of dementia.
Yamaguchi
Haruyasu
H
Gunma University School of Health Sciences, 3-39-15 Showa-machi, Maebashi 371-8514, Japan. yamaguti@health.gunma-u.ac.jp
D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications / Q000473:pathology*; D016229:Amyloid beta-Peptides / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000473:pathology*; D003704:Dementia / Q000209:etiology / Q000473:pathology; D006801:Humans; D058225:Plaque, Amyloid / Q000473:pathology*; D013997:Time Factors
D016229:Amyloid beta-Peptides