title: Factors affecting endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound during IVF treatment.
abstract: BACKGROUND
  No information exists in the literature regarding the factors affecting the blood flow towards the endometrial and subendometrial regions during IVF treatment.
  
  
  METHODS
  We examined the effect of women's age, their smoking habits, their type of infertility (i.e. primary or secondary) and parity, causes of infertility and serum estradiol (E2) concentration on endometrial and subendometrial blood flows as measured by a three-dimensional (3D) power Doppler ultrasound during IVF treatment. All patients received a standard long protocol of ovarian stimulation and serum E2 concentration was determined on the day of hCG. 3D ultrasound examination with power Doppler was performed on the day of oocyte collection to determine vascularization index (VI), flow index (FI) and vascularization flow index (VFI) of endometrial and subendometrial regions.
  
  
  RESULTS
  The age of women, their smoking habits, their types of infertility and parity and causes of infertility had no effect on the endometrial and subendometrial 3D power Doppler flow indices. There was a negative correlation between serum E(2) concentration and endometrial FI (r = -0.109; P = 0.006).
  
  
  CONCLUSIONS
  Endometrial blood flow in IVF treatment was negatively affected by serum E2 concentration only.
authors.affiliation: Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China. nghye@hkucc.hku.hk
authors.forename: Ernest Hung Yu
authors.initials: EH
authors.lastname: Ng
authors.forename: Carina Chi Wai
authors.initials: CC
authors.lastname: Chan
authors.forename: Oi Shan
authors.initials: OS
authors.lastname: Tang
authors.forename: William Shu Biu
authors.initials: WS
authors.lastname: Yeung
authors.forename: Pak Chung
authors.initials: PC
authors.lastname: Ho
mesh_terms: D000328:Adult; D000367:Age Factors; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004717:Endometrium / Q000098:blood supply* / Q000000981:diagnostic imaging*; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D021621:Imaging, Three-Dimensional; D007247:Infertility, Female / Q000000981:diagnostic imaging / Q000628:therapy; D010298:Parity; D011247:Pregnancy; D012907:Smoking; D018608:Ultrasonography, Doppler / Q000379:methods
chemical_list: D006063:Chorionic Gonadotropin; D004958:Estradiol