title: Saddle arterial embolus in a patient with Down syndrome.
abstract: We report acute thromboembolic events in a 14-year-old boy with Down syndrome and repaired atrioventricular septal defect. He presented with sudden onset of bilateral lower limb ischemia. Transesophageal echocardiography detected a thrombus in the right atrium. An arterial saddle embolus was removed following bilateral iliac embolectomy. Despite anticoagulation, he presented again with sudden bilateral lower limb ischemia and respiratory distress. Multiple pulmonary emboli and a thrombus in the right atrium were noted on imaging studies. An arterial embolus was removed from the abdominal aorta at the bifurcation. To our knowledge, this is the first report of a child or adolescent with a repaired congenital heart lesion and arterial embolism requiring embolectomy. This association and possible etiological factors are discussed.
authors.affiliation: Department of Paediatric Cardiology, Royal Brompton and Harefield Hospital, London, SW3 6NP, UK.
authors.forename: U R
authors.initials: UR
authors.lastname: Mohan
authors.affiliation: Department of Paediatric Cardiology, Royal Brompton and Harefield Hospital, London, SW3 6NP, UK.
authors.forename: J S
authors.initials: JS
authors.lastname: Mangat
authors.affiliation: Department of Paediatric Cardiology, Watford General Hospital, Vicarage Road, Watford, WD18 OHB, UK.
authors.forename: N
authors.initials: N
authors.lastname: Sutaria
authors.affiliation: Department of Paediatric Cardiology, Royal Brompton and Harefield Hospital, London, SW3 6NP, UK. r.franldin@rbh.nthames.nhs.uk.
authors.forename: R C G
authors.initials: RCG
authors.lastname: Franklin
mesh_terms: D000293:Adolescent; D001012:Aorta, Abdominal / Q000601:surgery; D001027:Aortography; D004314:Down Syndrome / Q000150:complications*; D017548:Echocardiography, Transesophageal; D017128:Embolectomy; D006325:Heart Atria / Q000601:surgery; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006345:Heart Septal Defects, Ventricular / Q000601:surgery*; D006801:Humans; D007083:Iliac Artery / Q000601:surgery; D007091:Image Processing, Computer-Assisted; D007511:Ischemia / Q000175:diagnosis* / Q000601:surgery; D007866:Leg / Q000098:blood supply*; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis* / Q000601:surgery; D012307:Risk Factors; D013923:Thromboembolism / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed