Vesicular monogamy?
Vesicular neurotransmitter transporters package transmitter into the lumen of synaptic vesicles for quantal release. However, the number of transporters that localize to each vesicle is not known. In this issue of Neuron, a study by Daniels et al. using the Drosophila neuromuscular junction and mutations of the vesicular glutamate transporter suggests that one transporter may suffice to fill each vesicle.
Krantz
David E
DE
Department of Psychiatry and Biobehavioral Sciences, Hatos Center for Neuropharmacology, The David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.
D000818:Animals; D004330:Drosophila / Q000378:metabolism; D009154:Mutation; D009469:Neuromuscular Junction / Q000378:metabolism; D013572:Synaptic Vesicles / Q000378:metabolism*; D050496:Vesicular Glutamate Transport Proteins / Q000235:genetics / Q000378:metabolism; D050481:Vesicular Neurotransmitter Transport Proteins / Q000378:metabolism*
D050496:Vesicular Glutamate Transport Proteins; D050481:Vesicular Neurotransmitter Transport Proteins