A synthetic, chloride-selective channel that alters chloride transport in epithelial cells.
An Ussing chamber was used to demonstrate that synthetic amphiphilic anion transporters function as chloride transporters in mammalian airway epithelial cells.
Pajewski
Robert
R
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8103, St. Louis, MO 63110, USA.
Garcia-Medina
Raquel
R
Brody
Steven L
SL
Leevy
W Matthew
WM
Schlesinger
Paul H
PH
Gokel
George W
GW
D000818:Animals; D001692:Biological Transport / Q000187:drug effects / Q000502:physiology; D018118:Chloride Channels / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*; D002712:Chlorides / Q000378:metabolism*; D004847:Epithelial Cells / Q000187:drug effects* / Q000378:metabolism; D008322:Mammals; D012137:Respiratory System / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors
D018118:Chloride Channels; D002712:Chlorides