title: The evidence for clinical efficacy of rose hip and seed: a systematic review.
abstract: BACKGROUND
  The objective of this review is to evaluate whether clinical research has gained any evidence of effectiveness of Rosa canina preparations.
  
  
  METHODS
  Several databases and other sources were searched to identify randomized controlled trials of Rosa canina preparations.
  
  
  RESULTS
  Trials were described in a narrative way, taking into consideration methodological quality scores. Four trials were included in this review and two were identified as subgroup analyses.
  
  
  CONCLUSIONS
  Moderate evidence exists for the use of a powder of the seeds and husks of a Rosa canina subspecies in patients suffering from osteoarthritis.
authors.affiliation: Institute of Forensic Medicine, University of Freiburg i.Br., Albertstr. 9, 79104 Freiburg i.Br., Germany.
authors.forename: C
authors.initials: C
authors.lastname: Chrubasik
authors.forename: R K
authors.initials: RK
authors.lastname: Duke
authors.forename: S
authors.initials: S
authors.lastname: Chrubasik
mesh_terms: D018771:Arthralgia / Q000188:drug therapy*; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D028321:Plant Preparations / Q000627:therapeutic use; D027826:Rosa / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*
chemical_list: D010936:Plant Extracts; D028321:Plant Preparations