title: Antioxidative flavanone glycosides from the branches and leaves of Viscum coloratum.
abstract: Two new flavanone glucosides, (2S)-homoeriodictyol 7,4'-di-O-beta-D-glucopyranoside (4) and (2R)-eriodictyol 7,4'-di-O-beta-D-glucopyranoside (5) were isolated from the branches and leaves of Viscum coloratum (KOMAR) NAKAI (Loranthaceae), along with three known flavanone glucosides: (2S)-homoeriodictyol 7-O-beta-D-glucopyranoside (1), (2S)-eriodictyol 7-O-beta-D-glucopyranoside (2), and (2S)-naringenin 7-O-beta-D-glucopyranoside (3). The structures of these compounds were elucidated using spectroscopic methods. The antioxidant activities of these isolated compounds were evaluated by colorimetric methods based on their scavenging effects on hydroxyl radicals and superoxide anion radicals, respectively. All the compounds showed potent albeit varied degrees of antioxidative activities and the structure-activity relationship is discussed.
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Yao
authors.forename: Zhi-Xin
authors.initials: ZX
authors.lastname: Liao
authors.forename: Qiong
authors.initials: Q
authors.lastname: Wu
authors.forename: Guang-Qing
authors.initials: GQ
authors.lastname: Lei
authors.forename: Zhi-Jun
authors.initials: ZJ
authors.lastname: Liu
authors.forename: Dao-Feng
authors.initials: DF
authors.lastname: Chen
authors.forename: Jia-Kuan
authors.initials: JK
authors.lastname: Chen
authors.forename: Tong-Shui
authors.initials: TS
authors.lastname: Zhou
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D044950:Flavanones / Q000737:chemistry* / Q000302:isolation & purification; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D017665:Hydroxyl Radical / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D016877:Oxidants / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis; D018515:Plant Leaves / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D013481:Superoxides / Q000737:chemistry; D028181:Viscum / Q000737:chemistry*; D014969:Xanthine Oxidase / Q000737:chemistry
chemical_list: C508625:(2R)-eriodictyol 7,4'-di-O-beta-D-glucopyranoside; C508624:(2S)-homoeriodictyol 7,4'-di-O-beta-D-glucopyranoside; D000975:Antioxidants; D044950:Flavanones; D016166:Free Radical Scavengers; D005960:Glucosides; D016877:Oxidants; D010936:Plant Extracts; D013481:Superoxides; D017665:Hydroxyl Radical; D014969:Xanthine Oxidase