title: Pemetrexed: mRNA expression of the target genes TS, GARFT and DHFR correlates with the in vitro chemosensitivity of human solid tumors.
authors.affiliation: Allgemeines Krankenhaus St. Georg, Hamburg, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Eismann
authors.forename: O
authors.initials: O
authors.lastname: Oberschmidt
authors.forename: M
authors.initials: M
authors.lastname: Ehnert
authors.forename: J
authors.initials: J
authors.lastname: Fleeth
authors.forename: F E
authors.initials: FE
authors.lastname: Lüdtke
authors.forename: S
authors.initials: S
authors.lastname: Struck
authors.forename: L
authors.initials: L
authors.lastname: Schulz
authors.forename: J
authors.initials: J
authors.lastname: Blatter
authors.forename: M M
authors.initials: MM
authors.lastname: Lahn
authors.forename: D
authors.initials: D
authors.lastname: Ma
authors.forename: C
authors.initials: C
authors.lastname: Niyikiza
authors.forename: P
authors.initials: P
authors.lastname: Paoletti
authors.forename: A R
authors.initials: AR
authors.lastname: Hanauske
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D005971:Glutamates / Q000494:pharmacology*; D006147:Guanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D000068437:Pemetrexed; D051026:Phosphoribosylglycinamide Formyltransferase / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics / Q000378:metabolism; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D005493:Folic Acid Antagonists; D005971:Glutamates; D012333:RNA, Messenger; D000068437:Pemetrexed; D006147:Guanine; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D051026:Phosphoribosylglycinamide Formyltransferase