title: Anaphylaxis to cisatracurium following negative skin testing.
abstract: General anaesthesia for the patient with a history of anaesthesia-related anaphylaxis is challenging. Precautions against anaphylaxis and the use of skin test negative drugs can reduce but not eliminate the risk. In the majority of such cases, subsequent anaesthesia is uneventful. However, the absence of a clearly identified triggering agent increases the difficulties facing the anaesthetist. We present a case of anaphylaxis to cisatracurium following a negative skin test.
authors.affiliation: Department of Anaesthesia and Pain Management, Alfred Hospital, Melbourne, Victoria.
authors.forename: B A
authors.initials: BA
authors.lastname: Fraser
authors.forename: J A
authors.initials: JA
authors.lastname: Smart
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D000768:Anesthesia, General / Q000009:adverse effects* / Q000379:methods; D001279:Atracurium / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000601:surgery; D005188:False Negative Reactions; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008579:Meningioma / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage / Q000009:adverse effects*; D019635:Neurosurgical Procedures / Q000379:methods; D010328:Patch Tests; D018570:Risk Assessment
chemical_list: D009466:Neuromuscular Blocking Agents; D001279:Atracurium; C101584:cisatracurium