title: Transient splenial lesion of corpus callosum associated with antiepileptic drug: conventional and diffusion-weighted magnetic resonance images.
abstract: Transient focal lesions of splenium of corpus callosum can be seen as a component of many central nervous system diseases, including antiepileptic drug toxicity. The conventional magnetic resonance (MR) findings of the disease are characteristic and include ovoid lesions with high signal intensity at T2-weighted MRI. Limited information exists about the diffusion-weighted MRI characteristics of these lesions vanishing completely after a period of time. We examined the conventional, FLAIR, and diffusion-weighted MR images of a patient complaining of depressive mood and anxiety disorder after 1 year receiving antiepileptic medication.
authors.affiliation: Department of Radiology, Uludag University Medical School, Bursa, Turkey. bahattinh@hotmail.com
authors.forename: B
authors.initials: B
authors.lastname: Hakyemez
authors.forename: C
authors.initials: C
authors.lastname: Erdogan
authors.forename: N
authors.initials: N
authors.lastname: Yildirim
authors.forename: G
authors.initials: G
authors.lastname: Gokalp
authors.forename: M
authors.initials: M
authors.lastname: Parlak
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D001007:Anxiety / Q000188:drug therapy; D003337:Corpus Callosum / Q000187:drug effects* / Q000473:pathology*; D003863:Depression / Q000188:drug therapy; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging
chemical_list: D000927:Anticonvulsants