title: [Study on new extraction technology of astragaloside IV].
abstract: OBJECTIVE
  To explore the possibility and the optimal extraction technology of astragaloside IV by SFE-CO2.
  
  
  METHODS
  According the content of astragaloside IV, the optimum extraction technology parameters such as extraction temperature, pressure, extraction time, velocity of fluid and co-solvent were investigated and the result was compared with that of water extraction.
  
  
  RESULTS
  The optimum technical parameters were as follows: Extracting pressure 40 Mpa, temperature 45 degrees C, extracting time 2h, co-solvent was 95% ethanol and its dosage was 4ml/g, the ratio of CO2 fluid was 10 kg/kg x h.
  
  
  CONCLUSIONS
  Extraction technology of astragaloside IV by SFE-CO2 is reliable, stable.
authors.affiliation: Department of Applied Biological Engineering, Shenzhen College of Polytechnic, Shenzhen.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Sun
authors.forename: Su
authors.initials: S
authors.lastname: Guan
authors.forename: Min
authors.initials: M
authors.lastname: Huang
mesh_terms: D027885:Astragalus propinquus / Q000737:chemistry*; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D012503:Saponins / Q000032:analysis / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D014315:Triterpenes / Q000032:analysis / Q000302:isolation & purification*
chemical_list: D012503:Saponins; D014315:Triterpenes; D002245:Carbon Dioxide; C052064:astragaloside A; D000431:Ethanol