title: [Study on the relations between overweight, obesity, blood pressures, serum lipids and glucose in schoolchildren of Shijiazhunag].
abstract: OBJECTIVE
  To explore the clustering character of overweight and obesity with multiple cardiovascular disease risk factors such as blood pressure, serum lipids and glucose, and to provide evidence for intervention in childhood.
  
  
  METHODS
  A cross-sectional study was conducted on 913 children aged 7-13 years in urban area of Shijiazhuang. Measurements included height, weight, systolic blood pressure (SBP), diastolic blood pressure (DBP) and fasting serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and serum glucose (GLU).
  
  
  RESULTS
  Overall prevalence rate of overweight and obesity was 29.24% (boys: 34.98% vs. girls: 24.23%). When compared with normal children, children with overweight or obesity had significantly higher levels of SBP, DBP, TC, TG but low HDL-C. The prevalence rates of high SBP, DBP, TC, TG, GLU and low HDL-C in overweight and obese children were higher than in normal children. After adjusted for gender and age, the odds ratios of overweight and obese children for high SBP, DBP, TC, TG, GLU and low HDL-C were 6.77, 3.22, 2.55, 6.42, 3.85 and 2.94 (95% CI: 4.15-11.04, 1.38-7.49, 1.59-4.11, 3.46-11.92, 1.69-8.78 and 1.83-4.73), respectively. Odds ratios of overweight and obese children holding any one, two or three of the selected six risk factors appeared to be 2.74, 13.15 and 15.33 (95% CI : 1.92-3.92, 6.69-25.87 and 4.17-56.39), respectively.
  
  
  CONCLUSIONS
  Childhood overweight and obesity increased the clustering of children's risk factors on cardiovascular diseases, as well as increasing the risk of children acquiring multiple cardiovascular disease risk factors. Controlling overweight and obesity would help early prevention on children from getting cardiovascular diseases.
authors.affiliation: Department of Environmental Health, School of Public Health, Hebei Medical University, Shijiazhuang 050017, China.
authors.forename: Feng-zhu
authors.initials: FZ
authors.lastname: Tan
authors.forename: Hui-min
authors.initials: HM
authors.lastname: Dong
authors.forename: Gui-hua
authors.initials: GH
authors.lastname: Feng
authors.forename: Chang-long
authors.initials: CL
authors.lastname: Feng
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zeng
authors.forename: Shao-xia
authors.initials: SX
authors.lastname: Dong
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiu-yin
authors.initials: XY
authors.lastname: Zhou
authors.forename: Zhan-jing
authors.initials: ZJ
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000517:prevention & control; D002648:Child; D002681:China / Q000453:epidemiology; D002947:Cities / Q000706:statistics & numerical data; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D012307:Risk Factors; D012574:Schools / Q000706:statistics & numerical data*
chemical_list: D001786:Blood Glucose; D008055:Lipids