title: delta-Lactone from Oedogonium capillare and their effects on rat ileum.
abstract: Antispasmodic activity-guided fractionation together with chemical analysis led to the isolation of one novel delta-lactone named oedogonolide from Oedogonium capillare. Identification was based on spectroscopic methods. The oedogonolide produces a significant antispasmodic effect on the contractions of the rat ileum induced by acetylcholine, histamine and barium chloride.
authors.affiliation: Laboratorio de Investigación de Productos Naturales, Escuela Superior de Ingeniería Química e Industias extractivas IPN, Punto fijo 16, col. Torres Lindavista cp 07708, México D.F., México. rmpg@prodigy.net.mx
authors.forename: Rosa Martha
authors.initials: RM
authors.lastname: Perez Gutierrez
authors.forename: Solis
authors.initials: S
authors.lastname: Rosario Vargas
authors.forename: Francisco
authors.initials: F
authors.lastname: Martinez Martinez
authors.forename: Efren
authors.initials: E
authors.lastname: Garcia Baez
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Figueroa Torres
mesh_terms: D000818:Animals; D007082:Ileum / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009119:Muscle Contraction / Q000187:drug effects; D051381:Rats
chemical_list: D007783:Lactones