[Tooth extraction under medication with acetylsalicylic acid].
OBJECTIVE
The purpose of this prospective study was to show and analyze the bleeding complications after teeth extraction under therapy with 100 mg acetylsalicylic acid (ASA) and to compare them to bleeding complications after teeth extraction in patients with a healthy blood profile.


METHODS
In 65 patients under medication with 100 mg ASA and in 252 healthy patients, 151/ 543 teeth were extracted and the bleeding complications monitored.


RESULTS
The postoperative bleeding frequency was 1.54% in the ASA 100 group and 1.59% in the healthy control group without any medication. No serious or uncontrollable postoperative bleedings arose in either group. All bleedings could be easily handled. No obvious difference concerning the bleeding frequency between the two groups was observed. The small number of bleeding events and the complexity of affecting parameters did not permit statistical tests.


CONCLUSIONS
It is not necessary to interrupt the medication of 100 mg acetylsalicylic acid given to prevent thromboembolism before tooth extractions.
Hemelik
M
M
Poliklinik für Chirurgische Zahn-, Mund- und Kieferheilkunde, Universität Bonn, Germany. g.wahl@uni-bonn.de
Wahl
G
G
Kessler
B
B
D000284:Administration, Oral; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D001241:Aspirin / Q000008:administration & dosage* / Q000009:adverse effects; D016063:Blood Loss, Surgical / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014081:Tooth Extraction
D000700:Analgesics; D001241:Aspirin