Reactivation of koi herpesvirus infections in common carp Cyprinus carpio.
Two co-habitation studies with common carp were conducted to determine whether latent infections of koi herpesvirus (KHV) exist. Fish were exposed to KHV using 2 different temperature profiles, which induced low and high initial mortality. Subsequently, certain groups of fish were co-habited with naive fish while others were not. Koi herpesvirus was reactivated in fish from 3 of the 5 experimental tanks. Reactivation of the virus occurred regardless of the initial mortality associated with the virus or whether fish were co-habited with naive fish. The reactivation of the virus in our experiments occurred several months after the initial exposure to KHV and appeared to be temperature dependent.
St-Hilaire
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CEFAS Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset DT4 8UB, UK. sthisoph@isu.edu
Beevers
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N
Way
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K
Le Deuff
R M
RM
Martin
P
P
Joiner
C
C
D000818:Animals; D002347:Carps; D004797:Enzyme-Linked Immunosorbent Assay; D005393:Fish Diseases / Q000635:transmission* / Q000821:virology*; D006564:Herpesviridae / Q000235:genetics*; D006566:Herpesviridae Infections / Q000635:transmission / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011156:Population Density; D013696:Temperature; D013997:Time Factors