Dihydrotrichodimerol and tetrahydrotrichodimerol, two new bisorbicillinoids, from a marine-derived Penicillium terrestre.
Two new bisorbicillinoids possessing an open-ended cage structure, dihydrotrichodimerol (1) and tetrahydrotrichodimerol (2), were isolated from a marine-derived Penicillium terrestre. Their structures were established by spectroscopic methods. Their cytotoxic activities against P388 and A-549 cell lines were preliminarily evaluated by the MTT method.
Liu
Weizhong
W
Key Laboratory of Marine Drugs, Chinese Ministry of Education, PR China.
Gu
Qianqun
Q
Zhu
Weiming
W
Cui
Chengbin
C
Fan
Guotao
G
D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D008386:Marine Biology; D010407:Penicillium / Q000737:chemistry*
D001952:Bridged-Ring Compounds; C473619:bisorbicillinolide; C508028:tetrahydrotrichodimerol