Successful treatment of eosinophilic pleural effusions following congenital heart surgery.
We report two children, age 7 months and 5 years, who underwent surgery for congenital heart disease and developed persistent pleural effusions with elevated eosinophil counts. Given the elevation of eosinophil counts in both blood and pleural fluid of these patients, it was considered that an allergic response might have caused the persistent effusion. In both cases, the effusion resolved within 48 hours after treatment with corticosteroids was begun. It is possible that postoperative eosinophilic pleural effusion may represent a subgroup of effusions that are more likely to respond to treatment with corticosteroids.
Perens
G S
GS
Department of Cardiology, Mattel Children's Hospital at UCLA, B2-427 MDCC, 10833 Le Conte Avenue, Los Angeles, CA, 90095-1743, USA. gperens@medret.ucla.edu.
Shannon
K M
KM
Department of Cardiology, Mattel Children's Hospital at UCLA, B2-427 MDCC, 10833 Le Conte Avenue, Los Angeles, CA, 90095-1743, USA.
Levi
D S
DS
Department of Cardiology, Mattel Children's Hospital at UCLA, B2-427 MDCC, 10833 Le Conte Avenue, Los Angeles, CA, 90095-1743, USA.
Drant
S
S
Department of Cardiology, Mattel Children's Hospital at UCLA, B2-427 MDCC, 10833 Le Conte Avenue, Los Angeles, CA, 90095-1743, USA.
D015505:Chest Tubes; D002675:Child, Preschool; D003131:Combined Modality Therapy; D018752:Diet, Fat-Restricted; D004802:Eosinophilia / Q000188:drug therapy*; D004804:Eosinophils / Q000187:drug effects; D005938:Glucocorticoids / Q000008:administration & dosage*; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D007958:Leukocyte Count; D008297:Male; D008776:Methylprednisolone Hemisuccinate / Q000008:administration & dosage*; D010289:Parenteral Nutrition, Total; D010996:Pleural Effusion / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy*
D005938:Glucocorticoids; D008776:Methylprednisolone Hemisuccinate