title: The LIFEdb database in 2006.
abstract: LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output table and the option to download search results in XML, (iii) the integration of data from cell-based screening assays addressing the influence of protein-overexpression on cell proliferation and (iv) the display of the relative expression ('Electronic Northern') of the genes under investigation using curated gene expression ontology information. LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface.
authors.affiliation: Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany. a.mehrle@dkfz.de
authors.forename: Alexander
authors.initials: A
authors.lastname: Mehrle
authors.forename: Heiko
authors.initials: H
authors.lastname: Rosenfelder
authors.forename: Ingo
authors.initials: I
authors.lastname: Schupp
authors.forename: Coral
authors.initials: C
authors.lastname: del Val
authors.forename: Dorit
authors.initials: D
authors.lastname: Arlt
authors.forename: Florian
authors.initials: F
authors.lastname: Hahne
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bechtel
authors.forename: Jeremy
authors.initials: J
authors.lastname: Simpson
authors.forename: Oliver
authors.initials: O
authors.lastname: Hofmann
authors.forename: Winston
authors.initials: W
authors.lastname: Hide
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Glatting
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Huber
authors.forename: Rainer
authors.initials: R
authors.lastname: Pepperkok
authors.forename: Annemarie
authors.initials: A
authors.lastname: Poustka
authors.forename: Stefan
authors.initials: S
authors.lastname: Wiemann
mesh_terms: D049109:Cell Proliferation; D019295:Computational Biology; D018076:DNA, Complementary / Q000737:chemistry; D030541:Databases, Genetic; D015870:Gene Expression; D005796:Genes; D023281:Genomics; D020407:Internet; D011506:Proteins / Q000032:analysis* / Q000235:genetics* / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D018511:Systems Integration; D014584:User-Computer Interface
chemical_list: D018076:DNA, Complementary; D011506:Proteins; D011993:Recombinant Fusion Proteins