title: HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins.
abstract: Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.
authors.affiliation: School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom.
authors.forename: Anoushka
authors.initials: A
authors.lastname: Davé
authors.forename: David J
authors.initials: DJ
authors.lastname: Jeenes
authors.forename: Donald A
authors.initials: DA
authors.lastname: Mackenzie
authors.forename: David B
authors.initials: DB
authors.lastname: Archer
mesh_terms: D001234:Aspergillus niger / Q000235:genetics / Q000378:metabolism; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D009247:NADH, NADPH Oxidoreductases / Q000235:genetics / Q000378:metabolism; D010105:Oxygenases / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D005656:Fungal Proteins; D018840:HSP70 Heat-Shock Proteins; D008565:Membrane Proteins; D012333:RNA, Messenger; D014157:Transcription Factors; D010105:Oxygenases; C019766:benzoate 1,2-dioxygenase; D009247:NADH, NADPH Oxidoreductases; C408906:cytochrome P450 reductase, Aspergillus niger