title: Central neurocytoma: report of two cases.
abstract: BACKGROUND
  Central neurocytomas are rare neuroectodermal tumors believed to arise from the subependymal matrix of the lateral ventricles.
  
  
  METHODS
  A 26-year-old woman and a 33-year-old man each had a large, heterogeneous, contrast enhancing mass in the lateral ventricles at the foramen of Monro causing bilateral hydrocephalus. The woman died after surgery, but the man is asymptomatic after three years.
  
  
  RESULTS
  Both tumors were composed of isomorphic rounded cells positive for synaptophysin, chromogranin and NSE, while some reacted for GFAP, vimentin and S-100 protein. Electron microscopy revealed neuropil-like tissue between cells, but synapses were rare.
authors.affiliation: Discipline of Neurosurgery, School of Medicine, State University of Campinas, Campinas, SP, Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Borges
authors.forename: Hoyama Costa
authors.initials: HC
authors.lastname: Pereira
authors.forename: Edmur Franco
authors.initials: EF
authors.lastname: Carelli
authors.forename: Yvens Barbosa
authors.initials: YB
authors.lastname: Fernandes
authors.forename: Leonardo
authors.initials: L
authors.lastname: Bonilha
authors.forename: Maria Fernanda
authors.initials: MF
authors.lastname: Roma
authors.forename: Verônica A
authors.initials: VA
authors.lastname: Zanardi
authors.forename: José R Menezes
authors.initials: JR
authors.lastname: Netto
authors.forename: André A
authors.initials: AA
authors.lastname: Schenka
authors.forename: Luciano S
authors.initials: LS
authors.lastname: Queiroz
mesh_terms: D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D018306:Neurocytoma / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure