Embolic protection: limitations of current technology and novel concepts.
Distal embolic event is one of the major limitations of coronary and non-coronary vascular interventions. Balloon and filter-based Embolic Protection Devices (EPDs) are a new class of interventional devices, used to prevent consequential morbidity and mortality of the distal embolic events. Data from first generation EPD supply proof of concept and show approximately 40% reduction in mortality and morbidity, when EPDs are used during saphenous vein grafts (SVGs) interventions. Current limitations of all first generation EPD technology taper their penetration. With breakthroughs in embolic protection technology, it is estimated that, in the near future, EPDs will be used with stenting in all high-risk lesions (SVGs, carotid arteries and acute coronary syndromes), become the standard of care and even be used in low risk cases.
Hamood
Hatem
H
Department of Cardiology, Bnai-Zion Medical Center, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, ISRAEL.
Makhoul
Nabeel
N
Hassan
Amin
A
Shefer
Arie
A
Rosenschein
Uri
U
D004617:Embolism / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D012307:Risk Factors; D014656:Vascular Surgical Procedures / Q000009:adverse effects*