Ciprofloxacin-induced torsade de pointes.
We report a rare case of torsade de pointes, a polymorphic ventricular tachycardia associated with QT interval prolongation, caused by intravenous ciprofloxacin given for pneumonia in a 22-year-old healthy Marine. Although the risk for quinolone-associated torsade de pointes appears to be low, caution is still warranted when given in the presence of pre-existing QT prolongation.
Flanagan
M Casey
MC
Mitchell
Eric S
ES
Haigney
Mark C P
MC
D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D017147:Defibrillators, Implantable; D004562:Electrocardiography / Q000187:drug effects; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D008297:Male; D018410:Pneumonia, Bacterial / Q000188:drug therapy; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy
D000890:Anti-Infective Agents; D002939:Ciprofloxacin