title: [Cerebral Aspergillus abscess in immunocompetent patient].
abstract: We report an unusual case of brain aspergillosis with multiple recurrent abscess in a 40 year-old immunocompetent woman, with good therapeutical outcome. The patient presented a subarachnoid hemorrhage caused by a ruptured pericallosal artery aneurysm and was submitted to a craniotomy for aneurysm surgery. Five months later, she developed multiple Aspergillus cerebral abscess. Two craniotomies and amphotericin B became necessary during treatment. Fourteen years later, she is asymptomatic. Treatment of brain aspergillosis abscess implied the combination of both surgical and drug therapy with amphotericin B.
authors.affiliation: Serviço de Neurocirurgia, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte MG, Brasil. pianettigpf@aol.com.br
authors.forename: Geraldo
authors.initials: G
authors.lastname: Pianetti Filho
authors.forename: Enio Roberto Pietra
authors.initials: ER
authors.lastname: Pedroso
authors.forename: Alexandre Varela
authors.initials: AV
authors.lastname: Giannetti
authors.forename: Rogério
authors.initials: R
authors.lastname: Darwich
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001230:Aspergillus / Q000302:isolation & purification; D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007121:Immunocompetence; D002532:Intracranial Aneurysm / Q000601:surgery; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000628:therapy; D011183:Postoperative Complications / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole