Coil occlusion of patent ductus arteriosus.
BACKGROUND
Coils are the only devices available for transcatheter occlusion of patent ductus arteriosus (PDA) in Japan. Since April 1999, we have introduced a 0.052-inch Gianturco coil (0.052-inch coil) to close PDA >or=2.5 mm.


RESULTS
A retrospective survey of the outcome of coil occlusions for PDA >or=2.5 mm before and after the 0.052-inch coil became available found that (1) the frequency of PDA >or=2.5 mm among all candidates for coil occlusion significantly increased after the availability of a 0.052-inch coil (p<0.01); (2) deployment complicated by migration (p<0.01), and prolonged procedure time (p<0.05) were significantly decreased after the introduction of the 0.052-inch coil. In a multivariate logistic regression model for uneventful deployment adjusted for age, pulmonary to systemic flow ratio, and use of a 0.052-inch coil, use of the 0.052-inch coil significantly decreased eventful deployment (p<0.05); and (3) successful deployment of a coil for PDA >or=4 mm significantly increased with the 0.052-inch coil (p<0.01). Complete occlusion was achieved once deployment was successful.


CONCLUSIONS
Introduction of the 0.052-inch coil decreased complicated coil occlusion deployment for PDA >or=2.5 mm, and contributed to a better likelihood of coil occlusion for PDA >or=4 mm.
Tomita
Hideshi
H
Department of Pediatrics, Sapporo Medical University School of Medicine, Japan. tomitah@sapmed.ac.jp
Takamuro
Motoki
M
Fuse
Shigeto
S
Horita
Norihisa
N
Hatakeyama
Kinya
K
Tsutsumi
Hiroyuki
H
Yazaki
Satoshi
S
Echigo
Shigeyuki
S
Kimura
Kohji
K
D021721:Balloon Occlusion / Q000295:instrumentation / Q000379:methods*; D006328:Cardiac Catheterization; D004374:Ductus Arteriosus, Patent / Q000628:therapy*; D004867:Equipment Design; D006801:Humans; D007564:Japan; D015999:Multivariate Analysis; D016017:Odds Ratio; D012044:Regression Analysis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012449:Safety; D016896:Treatment Outcome