title: The 2-year stability of neurological soft signs after a first episode of non-affective psychosis.
abstract: We examined the 2-year stability of neurological soft signs (NSS) in 29 patients after a first episode of psychosis. The numbers of NSS at inclusion and at 2 years follow-up were similar, but there was a significant increase in the numbers of NSS in the sub-group of patients whose dosage of antipsychotic medication had increased over time.
authors.affiliation: Department of Psychiatry, University Hospital Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands. m.p.m.boks@psych.azu.nl
authors.forename: Marco P M
authors.initials: MP
authors.lastname: Boks
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Selten
authors.forename: Stuart
authors.initials: S
authors.lastname: Leask
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Van den Bosch
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D015897:Comorbidity; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009422:Nervous System Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology*; D009460:Neurologic Examination / Q000187:drug effects / Q000706:statistics & numerical data; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D013223:Statistics as Topic
chemical_list: D014150:Antipsychotic Agents