title: [The significance of microvessel density and CD34 expression in nasal polyps].
abstract: OBJECTIVE
  To study the clinicopathologic significance of microvessel density (MVD) and the expression of CD34 in human nasal polyps.
  
  
  METHODS
  Using Elivision Plus immunohistochemistry method. Thirty cases of normal inferior turbinate, 60 cases of nasal polyps were stain with CD34.
  
  
  RESULTS
  MVD of CD34 marker showed higher in the group of nasal polyps than in the group of normal inferior turbinate (P <0.01). MVD in nasal polyps type II phase 3 and type III was higher than that in the nasal polyps type II phase (P < 0.01).
  
  
  CONCLUSIONS
  MVD is closely related with the formation edema and development of nasal polyps. Angiogenesis may play an important role in the development of nasal polyps.
authors.affiliation: Department of Otolaryngology, Third Hospital, Peking University, Beijing, 100083, China.
authors.forename: Li
authors.initials: L
authors.lastname: Yao
authors.forename: Xuepei
authors.initials: X
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Lu
authors.forename: Weihua
authors.initials: W
authors.lastname: Yin
mesh_terms: D000293:Adolescent; D000328:Adult; D018952:Antigens, CD34 / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D055806:Microvessels; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism* / Q000473:pathology; D009389:Neovascularization, Pathologic; D055815:Young Adult
chemical_list: D018952:Antigens, CD34