Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003.
The proportion of Staphylococcus aureus isolates that were methicillin resistant (MRSA) increased from 35.9% in 1992 to 64.4% in 2003 for hospitals in the National Nosocomial Infections Surveillance system. During the same period, there was a decrease in resistance rates for several non- beta -lactam drugs among the MRSA isolates.
Klevens
R Monina
RM
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. rmk2@cdc.gov
Edwards
Jonathan R
JR
Tenover
Fred C
FC
McDonald
L Clifford
LC
Horan
Teresa
T
Gaynes
Robert
R
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006801:Humans; D007362:Intensive Care Units / Q000639:trends*; D016106:Methicillin Resistance; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D013997:Time Factors; D014481:United States / Q000453:epidemiology
D000900:Anti-Bacterial Agents