[Multiple fibromas in systemic mastocytosis].
An adult man with systemic mastocytosis developed multiple fibromas within his involved skin, predominantly in the intertriginous areas. Friction in the intertriginous areas and scratching due to severe itch may have induced the release of mast cell factors which subsequently resulted in fibroma formation.
Klepper
Ludger
L
Hautklinik, Städtisches Krankenhaus Hildesheim. klepper_l@gmx.de
Tronnier
Michael
M
D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D000982:Antipruritics / Q000627:therapeutic use; D001706:Biopsy; D005350:Fibroma / Q000209:etiology*; D006651:Histocytochemistry; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use; D008297:Male; D034721:Mastocytosis, Systemic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011701:PUVA Therapy; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology*; D014299:Trimipramine / Q000627:therapeutic use; D014582:Urticaria Pigmentosa / Q000175:diagnosis / Q000473:pathology
D000929:Antidepressive Agents, Tricyclic; D000982:Antipruritics; D014299:Trimipramine; D007665:Ketotifen