title: [Clinical research of artificial larynx].
abstract: OBJECTIVE
  Using delayed degradation bone matrix gelatin (BMG) to repair the defect of laryngeal frame for the goal of laryngeal external form and function recovery.
  
  
  METHODS
  Partial laryngectomy and total laryngectomy were performed in nine cases with laryngeal cancer, then delayed degradation BMG be implanted in the defect of laryngeal frame or inside sterno hyoid muscle to build the laryngeal external form. In the same time the delayed degradation BMG be implanted in the crico-arytenoid muscle and around fibre with nerve ending, then embedding and sewing up to recover the swallow function and to prevent deglutition disorder.
  
  
  RESULTS
  The delayed degradation BMG were applied in nine cases to rebuild new larynx, five of them were performed vertical partial laryngectomy and two total laryngectomy. The effect is satisfied after 15 years followed up. Eight of them rebuild the laryngeal external form and function, one patient need put on tube for long-term and cramming to speaking.
  
  
  CONCLUSIONS
  Applying delayed degradation BMG to repair the laryngeal defect not only rebuild the laryngeal external form, but also recover the laryngeal function. It is an ideal bioactivity material and best choice for the new larynx rebuilding in the operation now.
authors.affiliation: Department of Otolaryngology, Hainan Provincial People's Hospital, Haikou, 570311, China. euangweimin5187@163.com
authors.forename: Guangyi
authors.initials: G
authors.lastname: Kuang
authors.forename: Jianfei
authors.initials: J
authors.lastname: Chen
authors.forename: Huiming
authors.initials: H
authors.lastname: Yi
mesh_terms: D000328:Adult; D000368:Aged; D001857:Bone Matrix / Q000737:chemistry; D005780:Gelatin / Q000627:therapeutic use*; D006801:Humans; D007825:Laryngectomy; D007830:Larynx / Q000601:surgery*; D007831:Larynx, Artificial; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*
chemical_list: D005780:Gelatin