Relationships between the N-glycan structures and biological activities of recombinant human erythropoietins produced using different culture conditions and purification procedures.
Yuen
C T
CT
National Institute for Biological Standards and Control, Potters Bar, Herts., UK.
Storring
P L
PL
Tiplady
R J
RJ
Izquierdo
M
M
Wait
R
R
Gee
C K
CK
Gerson
P
P
Lloyd
P
P
Cremata
J A
JA
D000818:Animals; D002236:Carbohydrate Conformation; D018929:Cell Culture Techniques; D004921:Erythropoietin / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D051379:Mice; D011134:Polysaccharides / Q000737:chemistry*; D011487:Protein Conformation; D020033:Protein Isoforms / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism; D011994:Recombinant Proteins / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*
D011134:Polysaccharides; D020033:Protein Isoforms; D011994:Recombinant Proteins; D004921:Erythropoietin