Preload and flow propagation velocity: insight into patients with uremia and different left ventricular systolic function.
OBJECTIVE
The aim of this study was to investigate the changes of flow propagation velocity (FPV) after regular hemodialysis (H/D) in patient who were uremic with different baseline left ventricular (LV) functions.


METHODS
In all, 24 patients with uremia and abnormal LV systolic function were enrolled in this study and 30 patients with uremia and normal LV systolic performance served as the control group. All patients had in sinus rhythm and underwent a comprehensive transthoracic echocardiographic examination and mitral FPV by color M-mode echocardiography before and after H/D.


RESULTS
The decline in FPV before H/D was proportional to the decline in the baseline LV function, whereas FPV after H/D varied according to the LV ejection fraction. An obvious decrement of FPV for patients with normal LV systolic function was noted, but no obvious difference was seen for patients with abnormal LV systolic function.


CONCLUSIONS
FPV was strongly preload dependent for patients with normal LV systolic function. It was not significantly influenced by preload for patients with abnormal LV systolic function. FPV is a relatively good diastolic parameter for investigating patients with LV systolic dysfunction.
Hsiao
Shih-Hung
SH
Division of Cardiology, Internal Medicine Department, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Republic of China.
Huang
Wei-Chen
WC
Lee
Tao Yu
TY
Sy
Cheng Len L
CL
Lin
Shih-Kai
SK
Liu
Chun-Peng
CP
D001783:Blood Flow Velocity; D001794:Blood Pressure; D003326:Coronary Circulation; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013318:Stroke Volume; D016896:Treatment Outcome; D014511:Uremia / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*