title: TCDB: the Transporter Classification Database for membrane transport protein analyses and information.
abstract: The Transporter Classification Database (TCDB) is a web accessible, curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from a variety of living organisms. TCDB is a curated repository for factual information compiled from >10,000 references, encompassing approximately 3000 representative transporters and putative transporters, classified into >400 families. The transporter classification (TC) system is an International Union of Biochemistry and Molecular Biology approved system of nomenclature for transport protein classification. TCDB is freely accessible at http://www.tcdb.org. The web interface provides several different methods for accessing the data, including step-by-step access to hierarchical classification, direct search by sequence or TC number and full-text searching. The functional ontology that underlies the database structure facilitates powerful query searches that yield valuable data in a quick and easy way. The TCDB website also offers several tools specifically designed for analyzing the unique characteristics of transport proteins. TCDB not only provides curated information and a tool for classifying newly identified membrane proteins, but also serves as a genome transporter-annotation tool.
authors.affiliation: Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA. msaier@ucsd.edu
authors.forename: Milton H
authors.initials: MH
authors.lastname: Saier
authors.forename: Can V
authors.initials: CV
authors.lastname: Tran
authors.forename: Ravi D
authors.initials: RD
authors.lastname: Barabote
mesh_terms: D030562:Databases, Protein; D006801:Humans; D020407:Internet; D026901:Membrane Transport Proteins / Q000737:chemistry / Q000145:classification* / Q000502:physiology; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface
chemical_list: D026901:Membrane Transport Proteins