Acute pancreatitis associated with omeprazole.
Since their introduction in the late 1980s, proton pump inhibitors (PPI) have demonstrated gastric acid suppression superior to that of histamine H2-receptor blockers. This class of drugs has improved the treatment of various acid-peptic disorders, including gastroesophageal reflux disease, peptic ulcer disease, and nonsteroidal anti-inflammatory drug-induced gastropathy. PPIs have minimal side effects and few significant drug interactions. They are generally considered safe for long-term treatment. We present a rare side effect, acute pancreatitis, occurring in a patient who was treated with the proton pump inhibitor omeprazole.
Youssef
S S
SS
James H. Quillen Veterans Affairs and James H. Quillen College of Medicine, Johnson City, TN, USA.
Iskandar
S B
SB
Scruggs
J
J
Roy
T M
TM
D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009853:Omeprazole / Q000009:adverse effects*; D010195:Pancreatitis / Q000139:chemically induced*; D054328:Proton Pump Inhibitors
D000897:Anti-Ulcer Agents; D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D009853:Omeprazole