Autoinducer 2 affects biofilm formation by Bacillus cereus.
Cell-free supernatants from growing Bacillus cereus strain ATCC 10987 induced luminescence in a Photorhabdus luminescens DeltaluxS mutant, indicating the production of functional autoinducer 2 (AI-2). The exogenous addition of in vitro synthesized AI-2 had an inhibitory effect on biofilm formation by B. cereus and promoted release of the cells from a preformed biofilm.
Auger
Sandrine
S
Microbiologie et Génétique Moléculaire, INRA (UMR1238), CNRS (UMR2585), INAPG, F-78850 Thiverval-Grignon, France.
Krin
Evelyne
E
Aymerich
Stéphane
S
Gohar
Michel
M
D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development*; D003470:Culture Media; D015964:Gene Expression Regulation, Bacterial; D006714:Homoserine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007783:Lactones / Q000378:metabolism* / Q000494:pharmacology*; D015398:Signal Transduction
D003470:Culture Media; D007783:Lactones; C091088:N-octanoylhomoserine lactone; D006714:Homoserine