High-capacity functional protein encapsulation in nanoengineered polypeptide microcapsules.
Addition of polyethylene glycol to aqueous assembly solutions of oppositely charged polypeptides enables high-capacity "loading" of functional protein in biocompatible microcapsules by template-supported layer-by-layer nanoassembly.
Zhi
Zheng-Liang
ZL
School of Biological Sciences, University of Liverpool, UK. zzhi@liverpool.ac.uk
Haynie
Donald T
DT
D000327:Adsorption; D005949:Glucose Oxidase / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D010455:Peptides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011099:Polyglutamic Acid / Q000737:chemistry; D011107:Polylysine / Q000737:chemistry; D012996:Solutions / Q000737:chemistry; D013499:Surface Properties; D014867:Water / Q000737:chemistry
D010455:Peptides; D012996:Solutions; D014867:Water; D011107:Polylysine; D011099:Polyglutamic Acid; D011092:Polyethylene Glycols; D005949:Glucose Oxidase