title: Relating cell killing to inactivation of critical components.
abstract: In this paper I relate the loss of CFU following a life-threatening treatment to the inactivation of critical components. Equations are used to calculate the loss of CFU following isothermal and temperature-scanning treatments, and the results are discussed in relation to differential scanning calorimetry of bacteria.
authors.affiliation: University of Bristol, Collagen Research Group, School of Veterinary Science, Langford, Bristol, UK. Chris.Miles@bristol.ac.uk
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Miles
mesh_terms: D001419:Bacteria / Q000254:growth & development* / Q000378:metabolism; D002152:Calorimetry, Differential Scanning; D015169:Colony Count, Microbial; D004269:DNA, Bacterial / Q000737:chemistry* / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry* / Q000378:metabolism; D006358:Hot Temperature; D008954:Models, Biological; D009691:Nucleic Acid Denaturation; D011489:Protein Denaturation; D012270:Ribosomes / Q000737:chemistry* / Q000378:metabolism
chemical_list: D004269:DNA, Bacterial; D012321:DNA-Directed RNA Polymerases