Newborn infant with maternal anti-SSA antibody-induced complete heart block accompanying cardiomyopathy.
Newborn case of maternal anti-SSA antibody-induced congenital complete heart block (CCHB) accompanying cardiomyopathy is presented. Unexpectedly, she died of ventricular tachycardia, not bradycardia, 6 days after birth. Autopsy revealed left ventricular cardiomyopathy with endocardial fibroelastosis. Thus, when evaluating fetal cardiac performance in cases of maternal anti-SSA antibody-induced CCHB, it is necessary to pay attention to myocardial attributes such as endocardial hyperplasia.
Iida
Midori
M
Department of Pediatric Cardiology and Pathology, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Japan.
Inamura
Noboru
N
Takeuchi
Makoto
M
D000974:Antibodies, Antinuclear / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology; D001344:Autopsy; D009202:Cardiomyopathies / Q000276:immunology / Q000473:pathology*; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006327:Heart Block / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D009206:Myocardium / Q000473:pathology; D011247:Pregnancy; D011296:Prenatal Diagnosis
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; C035356:SS-A antibodies