High serum leptin levels in depressive disorders with atypical features.
Leptin is thought to be related to vegetative symptoms of depression such as alterations in food intake and weight. Fifty-seven drug-free patients and 26 healthy controls were enrolled in this study. We have found that the serum leptin levels were higher in patients with atypical depressive disorder than in controls, but not in patients with non-atypical depressive disorder, however, body mass index, age, and gender were not significantly different between these groups. Probably, these findings seem to be associated with some features of the atypical depressive disorders such as weight gain, a result of hyperphagia.
Gecici
Omer
O
Department of Psychiatry, Medical Faculty, Kocatepe University, Afyon, Turkey. drogecici@yahoo.com
Kuloglu
Murat
M
Atmaca
Murad
M
Tezcan
A Ertan
AE
Tunckol
Hikmet
H
Emül
H Murat
HM
Ustundag
Bilal
B
D000328:Adult; D015992:Body Mass Index; D003866:Depressive Disorder / Q000097:blood* / Q000523:psychology*; D005260:Female; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood*; D008297:Male; D015430:Weight Gain
D007328:Insulin; D020738:Leptin; D019382:Human Growth Hormone; D006854:Hydrocortisone