An autopsy case of postpartum acute myocardial infarction associated with postpartum ergot alkaloids administration in old-aged pregnant women.
Cases of acute myocardial infarction (AMI) that occur during pregnancy or postpartum are rarely reported. Ergot derivatives are known to induce the spasmodic contraction of coronary arteries. Administration of ergot derivatives can cause AMI, even in normal healthy people. In several reported cases, ergot derivatives triggered severe AMI during the postpartum period. Here, we report the case of a forty-year-old woman who was successfully impregnated by artificial fertilization and died after treatment with ergot derivatives. The autopsy revealed AMI with severe coronary atherosclerosis. This is the first case that reports aggravation of pre-existent severe coronary atherosclerosis after postpartum infusion of ergot derivatives.
Eom
Minseob
M
Department of Forensic Medicine, Chonbuk National University College of Medicine, 2-20 San, Keumam-dong, Dukjin-gu, Jeonju, Chonbuk 561-180, Korea.
Lee
Jeong-Heon
JH
Chung
Jae-Hun
JH
Lee
Ho
H
D000328:Adult; D003324:Coronary Artery Disease / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D004876:Ergot Alkaloids / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008423:Maternal Age; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D049590:Postpartum Period; D011247:Pregnancy
D004876:Ergot Alkaloids