title: HvrBase++: a phylogenetic database for primate species.
abstract: HvrBase++ is the improved and extended version of HvrBase. Extensions are made by adding more population-based sequence samples from all primates including humans. The current collection comprises 13,873 hypervariable region I (HVRI) sequences and 4940 hypervariable region II (HVRII) sequences. In addition, we included 1376 complete mitochondrial genomes, 205 sequences from X-chromosomal loci and 202 sequences from autosomal chromosomes 1, 8, 11 and 16. In order to reduce the introduction of erroneous data into HvrBase++, we have developed a procedure that monitors GenBank for new versions of the current data in HvrBase++ and automatically updates the collection if necessary. For the stored sequences, supplementary information such as geographic origin, population affiliation and language of the sequence donor can be retrieved. HvrBase++ is Oracle based and easily accessible by a web interface (http://www.hvrbase.org). As a new key feature, HvrBase++ provides an interactive graphical tool to easily access data from dynamically created geographical maps.
authors.affiliation: Heinrich-Heine-University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.
authors.forename: Jochen
authors.initials: J
authors.lastname: Kohl
authors.forename: Ingo
authors.initials: I
authors.lastname: Paulsen
authors.forename: Thomas
authors.initials: T
authors.lastname: Laubach
authors.forename: Achim
authors.initials: A
authors.lastname: Radtke
authors.forename: Arndt
authors.initials: A
authors.lastname: von Haeseler
mesh_terms: D000818:Animals; D033481:Chromosomes, Mammalian / Q000737:chemistry; D003196:Computer Graphics; D004272:DNA, Mitochondrial / Q000737:chemistry; D030561:Databases, Nucleic Acid; D005828:Genetics, Population; D006801:Humans; D020407:Internet; D010802:Phylogeny; D011323:Primates / Q000145:classification* / Q000235:genetics*; D017422:Sequence Analysis, DNA; D014584:User-Computer Interface
chemical_list: D004272:DNA, Mitochondrial