Penicillium marneffei infection: an AIDS-defining illness.
A 29-year-old HIV seropositive male patient from Manipur presented with fever, cough, weight loss and asymptomatic papules and nodules all over the body. Differential diagnoses of secondary syphilis, histoplasmosis, cryptococcosis and penicilliosis were considered. Histopathological and mycological study of the skin biopsy tissue, and blood culture confirmed the diagnosis of penicilliosis. Although penicilliosis, an AIDS-defining illness, is restricted to Southeast Asia, more and more cases are being recognized in non-endemic countries.
Maniar
J K
JK
Department of Dermatovenereology and AIDS Medicine, K. J. Somaiya Medical College and Research Centre, Mumbai, India. jkmaniar@vsnl.com
Chitale
A R
AR
Miskeen
Autar
A
Shah
Keyur
K
Maniar
Alok
A
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D003881:Dermatomycoses / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007194:India; D008297:Male; D010407:Penicillium / Q000302:isolation & purification*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
D000935:Antifungal Agents