title: [Spontaneous splenic hematoma: trauma injury or drug reaction or both?].
abstract: BACKGROUND
  Spontaneous splenic hematomas are uncommon and frequently associated with infectious, hematologic, or neoplastic diseases. Presentation is typically acute but progressive forms have been described.
  
  
  METHODS
  We report the case of a 45-year-old man consulting for abdominal pain that was found to be due to a spontaneous splenic hematoma. No recent injuries, infections, or hematologic, neoplastic or gastrointestinal diseases were found, but the patient had had a minor injury 9 months earlier and had been treated with selective serotonin reuptake inhibitors (venlafaxine) for the past year. This history suggested that the drug might play a role.
  
  
  CONCLUSIONS
  Although the likely cause of this splenic hematoma appears to be a minor injury 9 months before the onset of pain, we cannot rule out the possibility that selective serotonin reuptake inhibitor treatment was a predisposing factor.
authors.affiliation: Département de médecine interne, CHU Rouen-Boisguillaume, Rouen (76).
authors.forename: J-C
authors.initials: JC
authors.lastname: Chakarian
authors.forename: F
authors.initials: F
authors.lastname: Héron
authors.forename: C
authors.initials: C
authors.lastname: Belizna
authors.forename: F
authors.initials: F
authors.lastname: Hervé
authors.forename: J-H
authors.initials: JH
authors.lastname: Maillochaud
authors.forename: I
authors.initials: I
authors.lastname: Marie
authors.forename: H
authors.initials: H
authors.lastname: Lévesque
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000058:Accidental Falls; D000062:Accidents, Occupational; D003863:Depression / Q000188:drug therapy; D006406:Hematoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D000070599:Shoulder Injuries; D013158:Splenic Diseases / Q000175:diagnosis*
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors