title: New research finds possible treatment for latent HIV. Valproic acid used to deplete HIV.
abstract: Researchers have discovered a possible combination therapy that will help clear HIV from resting CD4 T-cells, which may open the doors to a new approach to eliminating HIV infection. The recent study shows that highly-active antiretroviral therapy (HAART) with subcutaneous enfuvirtide, the fusion inhibitor, plus oral valproic acid accelerated the clearance of HIV from resting T-cells in vivo.
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D015496:CD4-Positive T-Lymphocytes / Q000821:virology; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D014635:Valproic Acid / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014635:Valproic Acid