TCDB: the Transporter Classification Database for membrane transport protein analyses and information.
The Transporter Classification Database (TCDB) is a web accessible, curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from a variety of living organisms. TCDB is a curated repository for factual information compiled from >10,000 references, encompassing approximately 3000 representative transporters and putative transporters, classified into >400 families. The transporter classification (TC) system is an International Union of Biochemistry and Molecular Biology approved system of nomenclature for transport protein classification. TCDB is freely accessible at http://www.tcdb.org. The web interface provides several different methods for accessing the data, including step-by-step access to hierarchical classification, direct search by sequence or TC number and full-text searching. The functional ontology that underlies the database structure facilitates powerful query searches that yield valuable data in a quick and easy way. The TCDB website also offers several tools specifically designed for analyzing the unique characteristics of transport proteins. TCDB not only provides curated information and a tool for classifying newly identified membrane proteins, but also serves as a genome transporter-annotation tool.
Saier
Milton H
MH
Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA. msaier@ucsd.edu
Tran
Can V
CV
Barabote
Ravi D
RD
D030562:Databases, Protein; D006801:Humans; D020407:Internet; D026901:Membrane Transport Proteins / Q000737:chemistry / Q000145:classification* / Q000502:physiology; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface
D026901:Membrane Transport Proteins