The effects of mefenamic acid on the blood haemoglobin of the lizard, Uromastix hardwickii.
This study deals with the effect of 7.1 mg/day, 10.5 mg/day and 14 mg/day doses of mefenamic acid administered for 12 days to three groups of Uromastix hardwickii respectively. Individual blood samples were obtained from the anterior abdominal vein and hemoglobin content was determined. The hemoglobin in test was 5.1 g/100 ml compared to 8.0 g/100 ml of controls in experiment I and its amount remained almost similar in the case of experiment II, whereas, 4.5 g/100 ml was observed of test compared to 8.0 g/100 ml of their counterparts.
Ahmad
Mahmood
M
Department of Physiology, University of Karachi, Karachi 75270, Pakistan.
Hasan
Ruqaiya
R
Ahmad
Mansoor
M
Qureshi
Anila
A
Ahmed
Zulfiqar
Z
Mansoor
Shama
S
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D006454:Hemoglobins / Q000378:metabolism*; D007202:Indicators and Reagents; D008116:Lizards / Q000097:blood*; D008528:Mefenamic Acid / Q000494:pharmacology*; D008706:Methemoglobin / Q000031:analogs & derivatives / Q000737:chemistry; D012015:Reference Standards
D000894:Anti-Inflammatory Agents, Non-Steroidal; D006454:Hemoglobins; D007202:Indicators and Reagents; C007169:cyanomethemoglobin; D008528:Mefenamic Acid; D008706:Methemoglobin