HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins.
Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.
Davé
Anoushka
A
School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom.
Jeenes
David J
DJ
Mackenzie
Donald A
DA
Archer
David B
DB
D001234:Aspergillus niger / Q000235:genetics / Q000378:metabolism; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D009247:NADH, NADPH Oxidoreductases / Q000235:genetics / Q000378:metabolism; D010105:Oxygenases / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D005656:Fungal Proteins; D018840:HSP70 Heat-Shock Proteins; D008565:Membrane Proteins; D012333:RNA, Messenger; D014157:Transcription Factors; D010105:Oxygenases; C019766:benzoate 1,2-dioxygenase; D009247:NADH, NADPH Oxidoreductases; C408906:cytochrome P450 reductase, Aspergillus niger