title: [Peripheral neuropathy and deterioration of the cognitive functions associated to chronic exposure to organophosphates].
abstract: OBJECTIVE
  To analyze the relationship between the chronic exposure (EC) to organophosphated insecticides (IOF) with the presence of peripheral neuropathy (NP) and the deterioration of cognitive functions (DFC).
  
  
  METHODS
  Cross-section, comparative and observational.
  
  
  METHODS
  Workers with more than three months of seniority, who participated in any stage of the process of production of IOF were included, and those with alterations in the neurological function were excluded. Two control groups were made up: the first one, without direct exposure to IOF, and the second one, without any exposure whatsoever to IOF. A physical examination was practiced on inferior limbs and a motor neuroconduction of the fibular nerves was carried out. The Minimum Exam of the Mental State was set (Mental Mini). The sampling was not random.
  
  
  RESULTS
  It was found that the presence of DFC and the clinical data for NP were greater in the exposed group than in the controls, (p < 0.05). Besides, data with a tendency to the continuation in the parameters of latencies, widths and waves F for the motor neuroconduction of inferior limbs were presented.
  
  
  CONCLUSIONS
  The long term exposure to IOF is related to deterioration in the cognitive function; as well as to the neurological manifestations in inferior limbs that condition an injury in the peripheral nerve, without being conclusive about the loss of its function.
authors.affiliation: Hospital General de Zona con Medicina Familliar 2, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León. guerairene@yahoo.es
authors.forename: Irene
authors.initials: I
authors.lastname: Orozco-De Los Ríos
authors.forename: Pedro Miguel
authors.initials: PM
authors.lastname: Sánchez-Vizcaíno
authors.forename: Diego
authors.initials: D
authors.lastname: González-Ramírez
authors.forename: José
authors.initials: J
authors.lastname: García-Piñón
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003072:Cognition Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004576:Electromyography; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects*; D009946:Organothiophosphorus Compounds / Q000009:adverse effects*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D009946:Organothiophosphorus Compounds