title: Erythema elevatum diutinum as a first clinical manifestation for diagnosing HIV infection: case history.
abstract: BACKGROUND
  Erythema elevatum diutinum is a chronic and rare dermatosis that is considered to be a variant of leukocytoclastic vasculitis. It is probably mediated by immune complexes. It is generally associated with autoimmune, neoplastic and infectious processes. Recently, it has been added to the group of specific dermatoses that are associated with HIV.
  
  
  METHODS
  We report on the case of a patient who had erythema elevatum diutinum as the first clinical evidence for diagnosing HIV infection. Dapsone was used in the treatment of this patient, and partial regression of the lesions was achieved within 15 days, even before anti-retroviral therapy was prescribed.
  
  
  CONCLUSIONS
  When there is a diagnosis of erythema elevatum diutinum, HIV infection should be investigated, especially in atypical and exacerbated clinical manifestations.
authors.affiliation: Dermatology Department, Hospital Universitdrio Celso Pierro (HMCP), Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, Brazil. parover@ig.com.br
authors.forename: Patrícia Accioni
authors.initials: PA
authors.lastname: Rover
authors.forename: Caroline
authors.initials: C
authors.lastname: Bittencourt
authors.forename: Mariana Pimenta
authors.initials: MP
authors.lastname: Discacciati
authors.forename: Mariana Colombini
authors.initials: MC
authors.lastname: Zaniboni
authors.forename: Lúcia Helena de Fávaro
authors.initials: LH
authors.lastname: Arruda
authors.forename: Maria Letícia
authors.initials: ML
authors.lastname: Cintra
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004890:Erythema / Q000188:drug therapy / Q000209:etiology*; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000890:Anti-Infective Agents; D003622:Dapsone