New drugs from fat bugs?
Signal transduction cascades, such as Hedgehog (Hh) signaling, are potentially important targets for new drugs. A new study in this issue of Cell Metabolism identifies hedgehog signaling in the formation of the Drosophila fly body and in mammalian adipogenesis.
Rosen
Evan D
ED
Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.
D050156:Adipogenesis / Q000502:physiology*; D000818:Animals; D029721:Drosophila Proteins / Q000819:agonists / Q000502:physiology*; D004331:Drosophila melanogaster / Q000502:physiology; D053823:Hedgehog Proteins / Q000819:agonists / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D029721:Drosophila Proteins; D053823:Hedgehog Proteins; C077245:hh protein, Drosophila