title: Pizza consumption and the risk of breast, ovarian and prostate cancer.
abstract: Pizza has been favourably related to the risk of prostate cancer in North America. Scanty information, however, is available on sex hormone-related cancer sites. We therefore studied the role of pizza consumption on the risk of breast, ovarian and prostate cancers using data from three hospital-based case-control studies conducted in Italy between 1991 and 2002. These included 2569 women with breast cancer, 1031 with ovarian cancer, 1294 men with prostate cancer, and a total of 4864 controls. Compared with non-pizza eaters, the multivariate odds ratios for eaters were 0.97 (95% confidence interval (CI) 0.86-1.10) for breast, 1.06 (95% CI 0.89-1.26) for ovarian and 1.04 (95% CI 0.88-1.23) for prostate cancer. Corresponding estimates for regular eaters (i.e. > or =1 portion per week) were 0.92 (95% CI 0.78-1.08), 1.00 (95% CI 0.80-1.25) and 1.12 (95% CI 0.88-1.43), respectively. Our results do not show a relevant role of pizza on the risk of sex hormone-related cancers. The difference with selected studies from North America suggests that dietary and lifestyle correlates of pizza eating vary between different populations and social groups.
authors.affiliation: Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy. gallus@marionegri.it
authors.forename: Silvano
authors.initials: S
authors.lastname: Gallus
authors.forename: Renato
authors.initials: R
authors.lastname: Talamini
authors.forename: Cristina
authors.initials: C
authors.lastname: Bosetti
authors.forename: Eva
authors.initials: E
authors.lastname: Negri
authors.forename: Maurizio
authors.initials: M
authors.lastname: Montella
authors.forename: Silvia
authors.initials: S
authors.lastname: Franceschi
authors.forename: Attilio
authors.initials: A
authors.lastname: Giacosa
authors.forename: Carlo
authors.initials: C
authors.lastname: La Vecchia
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology*; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D005502:Food; D006801:Humans; D007558:Italy / Q000453:epidemiology; D018551:Solanum lycopersicum; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D011471:Prostatic Neoplasms / Q000453:epidemiology*; D012306:Risk; D011795:Surveys and Questionnaires