title: [Perforation of the nasal septum in cocaine abusers].
abstract: Cocaine has been used for centuries for its stimulating and euphoric effects, but it also possesses vasoconstrictive and thrombotic properties. The cocaine-induced lesions depend mainly on the method of administration. In the present case, in which cocaine was nasally inhaled, the perforation of the cartilaginous nasal septum propably result from a combination of factors, including the topical effects and the complications linked to the use of the drug. This clinical observation corresponds to a high level of the progressive nasal pathology associated with cocaine abuse.
authors.affiliation: Université de Liége, Belgique.
authors.forename: G
authors.initials: G
authors.lastname: Blaise
authors.forename: O
authors.initials: O
authors.lastname: Vanhooteghem
authors.forename: M
authors.initials: M
authors.lastname: De La Brassinne
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D019970:Cocaine-Related Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D009300:Nasal Septum / Q000293:injuries*; D009668:Nose Diseases / Q000209:etiology