[ALK-1 positive anaplastic large cell lymphoma of the lung. Report of a pediatric case].
Ki-1 anaplastic large cell non-Hodgkin lymphoma is a well recognized clinical entity. The main clinical feature includes lymphadenopathy with mediastinal sparing. In the extranodal disease, which occurs in approximately half of the cases, the skin is the most common site; bone marrow, lung and central nervous system are generally not involved. Anaplastic large cell lymphoma is more common among young people, in whom the prognosis is more favorable. Primary anaplastic large cell lymphoma of the lung is a rare clinical entity. Its clinical expression is similar to a high grade malignant lymphoma, and in most cases the diagnosis is made in advanced stages. We present a pediatric case with ALK-1 positive anaplastic large cell lymphoma of the lung.
Siordia-Reyes
A Georgina
AG
Servicio de Patología, Hospital de Pediatría, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D. F., México. georginasiordia@hotmail.com
Ferman-Cano
Floribel
F
Rodríguez-Velasco
Alicia
A
D030301:Activin Receptors, Type II; D002648:Child; D006801:Humans; D008175:Lung Neoplasms / Q000737:chemistry* / Q000175:diagnosis; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry* / Q000175:diagnosis; D008297:Male; D008565:Membrane Proteins / Q000032:analysis*
D008565:Membrane Proteins; C425364:ACVRL1 protein, human; D030301:Activin Receptors, Type II