title: Monitoring the effects of water pollution on Cyprinus carpio in Karakaya Dam Lake, Turkey.
abstract: Karakaya Dam Lake (KDL) is one of the most important water sources, both for irrigation and fishery, located in eastern part of Turkey. This study is concerned with the pollution of the lake contributed by urban, industrial and agricultural activities. The parameters selected for this aim were the enzymes commonly used as biomarkers of environmental pollution. The activity of glutathione S-transferase (GST), carboxylesterase (CE), lactate dehydrogenase (LDH), acid phosphatase (ACP) and aspartate amino transferase (AST) has been determined in liver tissue samples of Cyprinus carpio, a representative species of KDL. Furthermore, brain acetylcholinesterase (AChE) activity which is mainly affected by pesticides such as organophosphates, has been assayed. Chemical analysis results showed that KDL was polluted by various heavy metals as it was apparent from water, sediment and gill tissue. The activity of brain AChE was significantly lower in all localities than Tecimli area (St-5) where there is no agricultural and industrial activities in the immediate periphery. Thus, this change of AChE activity may relate to agricultural pollution in KDL. On the other hand, no significant differences were found for selected enzyme biomarkers, but condition factor (CF) or hepatosomatic index were significantly different from the St-5 samples, a result that may be attributed to water pollution in KDL by various contaminants.
authors.affiliation: Faculty of Arts and Science, Department of Biology, Environmental Toxicology Laboratory, Inonu University, 44069, Malatya, Turkey. mozmen@inonu.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Ozmen
authors.forename: Abbas
authors.initials: A
authors.lastname: Güngördü
authors.forename: F Zehra
authors.initials: FZ
authors.lastname: Kucukbay
authors.forename: R Elif
authors.initials: RE
authors.lastname: Güler
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D015415:Biomarkers; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D002347:Carps / Q000378:metabolism*; D004784:Environmental Monitoring; D005618:Fresh Water / Q000032:analysis; D019015:Geologic Sediments / Q000032:analysis; D005880:Gills / Q000737:chemistry; D005982:Glutathione Transferase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D019216:Metals, Heavy / Q000032:analysis / Q000633:toxicity; D009566:Nitrates / Q000032:analysis / Q000633:toxicity; D010710:Phosphates / Q000032:analysis / Q000633:toxicity; D014422:Turkeys; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*; D014876:Water Pollution / Q000009:adverse effects
chemical_list: D015415:Biomarkers; D019216:Metals, Heavy; D009566:Nitrates; D010710:Phosphates; D014874:Water Pollutants, Chemical; D007770:L-Lactate Dehydrogenase; D005982:Glutathione Transferase; D000110:Acetylcholinesterase