title: Long-term survival cases of lung cancer presented as solitary bone metastasis.
abstract: The prognosis of non-small cell lung carcinoma (NSCLC) with bone metastasis has been regarded as very poor. We report herein on two cases of NSCLC which presented as a solitary bone metastasis, were treated with surgical resection. Both these cases survived for over 5 years after their last operations. A 71-year-old-man was hospitalized with right crural pain. A diagnosis of squamous cell carcinoma of the left lower lobe with right fibula metastasis was made. A marginal resection of the right fibula was performed. After that, a left lower lobe lobectomy and systemic chemotherapy were carried out. He had a local recurrence in the right mediastinal lymph nodes eleven months after the operation. He received intraluminal and external radiation therapy and obtained complete remission. He has survived for 5 years without any other recurrence or metastasis. A 52-year-old-man was admitted to our hospital with left thigh pain. A diagnosis of adenocarcinoma of the right upper lobe with left thigh metastasis was made. A right upper lobe lobectomy and a resection of the left thigh tumor were performed. Three cycles of systemic chemotherapy were given after that. He has survived for 5 years since his last operation without any recurrence or metastasis.
authors.affiliation: Department of General and Cardiothoracic Surgery, Kanazawa University School of Medicine, Kanazawa, Japan.
authors.forename: Yasumitsu
authors.initials: Y
authors.lastname: Hirano
authors.forename: Makoto
authors.initials: M
authors.lastname: Oda
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsunezuka
authors.forename: Norihiko
authors.initials: N
authors.lastname: Ishikawa
authors.forename: Go
authors.initials: G
authors.lastname: Watanabe
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary*; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005360:Fibula; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D017741:Survivors