Fundus autofluorescence imaging in serous and drusenoid pigment epithelial detachments associated with age-related macular degeneration.
OBJECTIVE
To investigate the fundus autofluorescence (FAF) imaging findings in patients with serous and drusenoid pigment epithelial detachment (PED) associated with age-related macular degeneration (AMD).


METHODS
Observational case series.


METHODS
Fourteen eyes of 13 consecutive patients with serous (n = 10) and drusenoid (n = 4) PED were prospectively included.


RESULTS
In all cases of serous vascularized (n = 7) and avascular (n = 3) PED, the FAF signal was increased, corresponding to the area of detachment. In drusenoid PED, the FAF was either increased or decreased. The decreased signal was recorded in cases associated with pigmented clumping.


CONCLUSIONS
These findings are useful for a more detailed phenotyping of patients with PED associated with AMD. FAF may derive not only from lipofuscin, but also from other sources, such as sub-retinal pigment epithelium fluid.
Karadimas
Panagiotis
P
Medical Retina Unit, 1st Department of Ophthalmology, Henry Dunant Hospital, 107 Mesogion Avenue, 11526 Athens, Greece. t_karadimas@yahoo.com
Bouzas
Evrydiki A
EA
D000368:Aged; D000369:Aged, 80 and over; D003952:Diagnostic Imaging; D005260:Female; D005451:Fluorescein Angiography; D005453:Fluorescence; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008268:Macular Degeneration / Q000150:complications / Q000175:diagnosis*; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis* / Q000209:etiology; D015593:Retinal Drusen / Q000175:diagnosis* / Q000209:etiology; D044967:Serum
D007208:Indocyanine Green