title: [The calcipotriol-betamethasone dipropionate association].
abstract: The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues. A new galenic formulation allows to combine them in a single application. Dovobet (LEO Pharma) ointment is the association of calcipotriol 50 microg/g with betamethasone dipoprionate 0.5 mg/g. This formulation boosts the therapeutic activity of calcipotriol. It also decreases the irritative inflammatory reaction due to calcipotriol without increasing the atrophogenic risk of the dermocorticoid.
authors.affiliation: CHU du Sart Tilman, Service de Dermatopathologie, Liège.
authors.forename: F
authors.initials: F
authors.lastname: Henry
authors.forename: C
authors.initials: C
authors.lastname: Flagothier
authors.forename: P
authors.initials: P
authors.lastname: Delvoye
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000287:Administration, Topical; D001623:Betamethasone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007249:Inflammation; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: C055085:calcipotriene; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D002117:Calcitriol