title: Acute liver failure in children.
abstract: Acute liver failure (ALF) is a rare but devastating illness. Specific therapy to promote liver recovery is often not available, and the underlying cause of the liver failure is often unknown. This article examines current knowledge of the epidemiology, pathobiology, and treatment of ALF in children and identifies potential gaps in this knowledge for future study.
authors.affiliation: Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. john.bucuvalas@cchmc.org
authors.forename: John
authors.initials: J
authors.lastname: Bucuvalas
authors.forename: Nada
authors.initials: N
authors.lastname: Yazigi
authors.forename: Robert H
authors.initials: RH
authors.lastname: Squires
mesh_terms: D002648:Child; D006501:Hepatic Encephalopathy / Q000209:etiology; D006801:Humans; D017114:Liver Failure, Acute / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery*; D016031:Liver Transplantation