[Significance of the changes of urinary uric acid in OSAHS before and after UPPP].
OBJECTIVE
To assess the value of urinary uric acid excretion and urinary uric acid/creatinine ratio as the marker of obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after Uvulopalatopharyngoplasty (UPPP).


METHODS
Twenty three cases diagnosed as OSAHS by polysomnography (PSG) were treated as trial group, 12 cases excluded from OSAHS by PSG were taken as control group,and 15 patients of the trial group were treated by UPPP and were taken as before UPPP therapy group and after UPPP therapy group. The makers above were compared in these groups.


RESULTS
The overnight change in urinary uric acid/creatinine ratio in trial group is 0.46+/-0.25, and after UPPP therapy group (0.13+/-0.2) significantly lower than before UPPP therapy group (0.49 +/-0.32), P < 0.01.


CONCLUSIONS
The urinary uric acid excretion and overnight change in urinary uric acid/creatinine are good markers to determine the effects of UPPP on OSAHS.
Du
Xiaodong
X
Department of Otolaryngology-Head and Neck Surgery, the Fourth Hospital of Shuzhou University, Wuxi, 214062, China. entdxd@sina.com
Pu
Hongbo
H
Shu
Chang
C
Luan
Xinyong
X
D000328:Adult; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010159:Palate / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology* / Q000601:surgery / Q000652:urine*; D014527:Uric Acid / Q000652:urine*; D014609:Uvula / Q000601:surgery
D014527:Uric Acid; D003404:Creatinine