title: Long-term outcome of cadaveric pediatric en bloc transplantation--a 15-year experience.
abstract: Pediatric en bloc transplantation of infant organs into adult recipients is a recognized technique to expand the number of kidneys available for transplantation. We reviewed our experience with this technique over a 15-year period to determine the long-term outcomes. Twelve patients underwent pediatric en bloc transplantation from donors aged <4 years. All transplants functioned immediately with no graft thrombosis. Two patients died 12 and 10 years posttransplant with functioning grafts. The remaining 10 recipients experienced excellent graft function with a mean follow-up time of 73.8 months (range, 10 to 169 months) with no evidence of hyperfiltration injury. We conclude that pediatric en bloc transplantations achieve excellent long-term allograft function in selected recipients.
authors.affiliation: Department of Urology and Transplantation, Beaumont Hospital, Dublin, Ireland.
authors.forename: G P
authors.initials: GP
authors.lastname: Smyth
authors.forename: M P
authors.initials: MP
authors.lastname: Eng
authors.forename: R P
authors.initials: RP
authors.lastname: Power
authors.forename: D P
authors.initials: DP
authors.lastname: Hickey
authors.forename: D M
authors.initials: DM
authors.lastname: Little
mesh_terms: D000328:Adult; D000368:Aged; D002102:Cadaver; D002423:Cause of Death; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D016030:Kidney Transplantation / Q000379:methods* / Q000401:mortality / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors; D014019:Tissue Donors / Q000706:statistics & numerical data*; D016896:Treatment Outcome