Vinylation of aryl bromides using an inexpensive vinylpolysiloxane.
[reaction: see text] A mild and general method for the palladium-catalyzed vinylation of aryl bromides has been developed. The use of tetrabutylammonium fluoride (TBAF) as the activator and an inexpensive and nontoxic vinyl donor, 1,3,5,7-tetramethyl-1,3,5,7-tetravinylcyclotetrasiloxane (D(4)(V), 1), allows for a general and high-yielding preparation of substituted styrenes.
Denmark
Scott E
SE
Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, 61801, USA. denmark@scs.uiuc.edu
Butler
Christopher R
CR
D001965:Bromides / Q000737:chemistry*; D012833:Siloxanes / Q000737:chemistry*; D013343:Styrenes / Q000138:chemical synthesis*
D001965:Bromides; D012833:Siloxanes; D013343:Styrenes; C507689:1,3,5,7-tetramethyl-1,3,5,7-tetravinylcyclotetrasiloxane