[Chemoradiation in bladder cancer].
Bladder cancer is an urologic common tumor after prostate carcinoma. Radical treatment of localized invasive tumor is based on cystectomy. Surgical mutilation could be important when Bricker's urinary derivation is performed. Moreover, delated metastasis appeared frequently in spite of radical surgery. So, for selected patients, chemoradiotherapy is a valid alternative treatment to cystectomy. Cisplatin or derivatives were administered concurrently to radiation therapy up to 60-65 Gy. Patients underwent control cystoscopy at midtime of treatment in order to select responders from non responders. This review summarizes the main published series of radiochemotherapy in invasive bladder cancer. Results for local control, survivals, bladder preservation rates and toxicity are presented.
Durdux
Catherine
C
Onco-radiothérapie, Hôpital européen Georges Pompidou, 20, rue Leblanc, 75015 Paris. catherine.maulard-durdux@hop.egp.ap-hop-paris.fr
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy / Q000009:adverse effects / Q000379:methods; D015653:Cystectomy; D006801:Humans; D010865:Pilot Projects; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery
D000970:Antineoplastic Agents