Anterior uveitis and iris nodules that are associated with Langerhans cell histiocytosis.
OBJECTIVE
To describe a case of Langerhans cell histiocytosis (LCH) that involved the anterior uveal tract.


METHODS
Interventional case report.


METHODS
A retrospective review was conducted on a patient with iris nodules and anterior uveitis in the setting of LCH. Visual acuity and clinical findings that were noted on slit lamp biomicroscopy were extracted.


RESULTS
An 18-year-old male patient with unilateral anterior segment inflammation and iris nodules experienced visual improvement from 20/200 to 20/25 after treatment with a 5-day course of topical corticosteroids. Regression of the iris nodules and anterior segment inflammation was also noted. Bone marrow aspirate confirmed recurrent, active LCH.


CONCLUSIONS
The clinician should include LCH in the differential diagnosis when faced with anterior segment inflammation in conjunction with iris nodules. Additionally, LCH can be treated successfully with topical corticosteroid therapy.
Tsai
Julie H
JH
Cincinnati Eye Institute-NKY, Edgewood, Kentucky, USA.
Galaydh
Farah
F
Ching
Steven S T
SS
D000293:Adolescent; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006470:Hemorrhage / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007499:Iris Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D012189:Retrospective Studies; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity
D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone