Nebulin: does it measure up as a ruler?
A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the pointed end of actin filaments in striated muscle.
Fowler
Velia M
VM
Department of Cell Biology- CB163, The Scripps Research Institute, La Jolla, CA 92037, USA.
McKeown
Caroline R
CR
Fischer
Robert S
RS
D008841:Actin Cytoskeleton / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D008954:Models, Biological; D009124:Muscle Proteins / Q000502:physiology*; D018482:Muscle, Skeletal / Q000648:ultrastructure*; D051381:Rats; D012518:Sarcomeres / Q000502:physiology
D009124:Muscle Proteins; C035620:nebulin