title: Clinical profile of typhoid patients.
abstract: OBJECTIVE
  The present study was undertaken to determine the clinical profile of typhoid fever in hospitalised patients.
  
  
  METHODS
  Prospective cross-sectional study.
  
  
  METHODS
  Kathmandu Medical College and Teaching Hospital.
  
  
  METHODS
  Total of thirty patients above fifteen years of age who had clinical features strongly suggestive of typhoid fever and on blood culture found to be positive for Salmonella typhi were analysed for clinical features.
  
  
  RESULTS
  Among total of thirty cases, there were 17 (57%) males and 13 (43%) females. 86% of cases of typhoid fever clustered around 15-30 years of age. Predominant symptoms were fever (100%), headache (90%), abdominal Pain (37%) and constipation (33%). Common clinical signs were splenomegaly (37%), relative bradycardia (27%) and hepatomegaly (17%). None of the patients presented with complications.
  
  
  CONCLUSIONS
  The clinical profile of typhoid fever in our study revealed not much difference from that of other studies on typhoid fever. Rose spots were not noticed and we did not find a single case of complication of typhoid fever. Probably early initiation of antibiotics prevented the complications.
authors.affiliation: Department of Medicine, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal. kcmathura@wlink.com.np
authors.forename: K C
authors.initials: KC
authors.lastname: Mathura
authors.forename: D L
authors.initials: DL
authors.lastname: Gurubacharya
authors.forename: A
authors.initials: A
authors.lastname: Shrestha
authors.forename: S
authors.initials: S
authors.lastname: Pant
authors.forename: P
authors.initials: P
authors.lastname: Basnet
authors.forename: D B
authors.initials: DB
authors.lastname: Karki
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D009390:Nepal; D011446:Prospective Studies; D012485:Salmonella typhi / Q000472:pathogenicity*; D014435:Typhoid Fever / Q000503:physiopathology*