[Study on the effect of promoting intelligence development and preventing hypoxia/reoxygenation injury of selenium-banqiao-Codonopsis pilosula-overground part in mice].
OBJECTIVE
To study on the effect of promoting intelligence development and preventing Hypoxia/Reoxygenation injury of Selenium-Banqiao-Codonopsis pilosula-overground part in mice.


METHODS
Promoting Intelligence Development experiment was induced by PIA; Hypoxia/reoxygenation ingury model was established to observe the activity of ROS, SOD, MOD and CAT in blood.


RESULTS
Selenium-Banqiao-Codonopsis pilosula-overground part could enhance the learning and memory ability of old mice and obviously extend the swimming time of mice. It could also decrease the quality of ROS and MDA, increase the activity of SOD, but no significant effect on CAT.


CONCLUSIONS
Selenium-Banqiao-Codonopsis pilosula-overground part has effect on promoting intelligence development and preventing hypoxia/reoxygenation injury.
Xiao
Benjian
B
The Medical school of Hubei Institute for Nationalities, Enshi, Hubei.
Chen
Guodong
G
Lan
Zongping
Z
D000818:Animals; D029745:Codonopsis / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D000860:Hypoxia / Q000378:metabolism / Q000473:pathology*; D007360:Intelligence; D007858:Learning / Q000187:drug effects; D008568:Memory / Q000187:drug effects; D008569:Memory Disorders / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology*; D051379:Mice; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D015427:Reperfusion Injury / Q000378:metabolism / Q000473:pathology; D012643:Selenium
D004365:Drugs, Chinese Herbal; D012643:Selenium