Central neurocytoma: report of two cases.
BACKGROUND
Central neurocytomas are rare neuroectodermal tumors believed to arise from the subependymal matrix of the lateral ventricles.


METHODS
A 26-year-old woman and a 33-year-old man each had a large, heterogeneous, contrast enhancing mass in the lateral ventricles at the foramen of Monro causing bilateral hydrocephalus. The woman died after surgery, but the man is asymptomatic after three years.


RESULTS
Both tumors were composed of isomorphic rounded cells positive for synaptophysin, chromogranin and NSE, while some reacted for GFAP, vimentin and S-100 protein. Electron microscopy revealed neuropil-like tissue between cells, but synapses were rare.
Borges
Guilherme
G
Discipline of Neurosurgery, School of Medicine, State University of Campinas, Campinas, SP, Brazil.
Pereira
Hoyama Costa
HC
Carelli
Edmur Franco
EF
Fernandes
Yvens Barbosa
YB
Bonilha
Leonardo
L
Roma
Maria Fernanda
MF
Zanardi
Verônica A
VA
Netto
José R Menezes
JR
Schenka
André A
AA
Queiroz
Luciano S
LS
D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D018306:Neurocytoma / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure