title: Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.
authors.affiliation: Laboratorium für Organische Chemie, ETH Hönggerberg, HCI, 8093 Zürich, Switzerland.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Crane
authors.forename: Johannes
authors.initials: J
authors.lastname: Kaiser
authors.forename: Nicola L
authors.initials: NL
authors.lastname: Ramsden
authors.forename: Susan
authors.initials: S
authors.lastname: Lauw
authors.forename: Felix
authors.initials: F
authors.lastname: Rohdich
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Eisenreich
authors.forename: William N
authors.initials: WN
authors.lastname: Hunter
authors.forename: Adelbert
authors.initials: A
authors.lastname: Bacher
authors.forename: François
authors.initials: F
authors.lastname: Diederich
mesh_terms: D000962:Antimalarials / Q000138:chemical synthesis / Q000494:pharmacology*; D001665:Binding Sites; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D029968:Escherichia coli Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000494:pharmacology*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D019761:Phosphorus-Oxygen Lyases / Q000037:antagonists & inhibitors* / Q000737:chemistry; D013729:Terpenes / Q000378:metabolism*
chemical_list: D000962:Antimalarials; D004791:Enzyme Inhibitors; D029968:Escherichia coli Proteins; D005456:Fluorescent Dyes; D008024:Ligands; D013729:Terpenes; D019761:Phosphorus-Oxygen Lyases; C400181:ISPF protein, E coli