Association of increased body mass index and impaired endothelial function among Hispanic women.
We tested the hypothesis that an increased body mass index was similarly associated with impaired endothelial function as measured by flow-mediated dilation in a high-risk, Hispanic population of men and women living in northern Manhattan. The association of flow-mediated dilation and body mass index was significant in women (beta -0.16 +/- 0.04, p <0.0001) but not in men (beta -0.02 +/- 0.06, p = 0.72). This is the first study to demonstrate a gender-specific difference in endothelial function associated with body mass index.
Pulerwitz
Todd
T
Department of Medicine, Division of Cardiology, Columbia University, New York, New York, USA.
Grahame-Clarke
Cairistine
C
Rodriguez
Carlos J
CJ
Miyake
Yumiko
Y
Sciacca
Robert R
RR
Hirata
Kumiko
K
DiTullio
Marco R
MR
Boden-Albala
Bernadette
B
Sacco
Ralph L
RL
Homma
Shunichi
S
D000367:Age Factors; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D016014:Linear Models; D008297:Male; D015999:Multivariate Analysis; D009765:Obesity / Q000503:physiopathology*; D012737:Sex Factors; D014463:Ultrasonography; D014664:Vasodilation / Q000502:physiology*