title: Recognising F-response interference as a source of increased jitter in stimulated single fibre EMG.
abstract: OBJECTIVE
  To determine the source of an abnormal pattern of latency shifts leading to falsely high jitters in single fibre electromyography (SFEMG).
  
  
  METHODS
  We observed a sudden shortening of the latency to an individual single fibre spike component followed by a gradual return to baseline values during stimulation single fibre electromyography (SFEMG) of the facial muscle. The pattern could be reproduced in healthy controls.
  
  
  RESULTS
  The sudden decrease in latency proved to follow an additional discharge of the muscle fibre, not due to the external stimulus. This additional discharge was identified as an F-response.
  
  
  CONCLUSIONS
  The mechanism is thought to be a higher muscle fibre conduction velocity resulting from a temporary increase in stimulus frequency, in the form of an extra impulse along the muscle fibre represented by the F-response.
  
  
  CONCLUSIONS
  The typical abnormal pattern should be recognised because it can falsely increase the mean jitter. We advice to increase the time base to 50 ms if this pattern is observed and to exclude the affected potentials from jitter measurements.
authors.affiliation: Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. p.blijham@neuro.umcn.nl
authors.forename: P J
authors.initials: PJ
authors.lastname: Blijham
authors.forename: J G
authors.initials: JG
authors.lastname: van Dijk
authors.forename: E
authors.initials: E
authors.lastname: Stålberg
authors.forename: M J
authors.initials: MJ
authors.lastname: Zwarts
mesh_terms: D000465:Algorithms; D004558:Electric Stimulation / Q000379:methods; D004576:Electromyography; D005152:Facial Muscles / Q000503:physiopathology* / Q000528:radiation effects; D006801:Humans; D009468:Neuromuscular Diseases / Q000503:physiopathology; D011930:Reaction Time / Q000528:radiation effects*; D013997:Time Factors