Studies on nepalese crude drugs. XXVIII. Chemical constituents of Bhote Khair, the underground parts of Eskemukerjea megacarpum HARA.
From the underground parts of Eskemukerjea megacarpum HARA, two new stilbenes (14, 15) were isolated, together with a known coumarin, 5,7-dihydroxycoumarin (1), a tyramine derivative, trans-feruloyltyramine (2), two pyrogallol derivatives, gallic acid (3) and beta-glucogallin (4), four flavonoids, trifolin (5), hyperin (6), myricetin 3-O-beta-D-galactopyranoside (7), and myricitrin (8), five stilbenes, resveratorol (9), astringenin (10), piceid (11) astringin (12), and resveratorol 3-O-beta-D-(6-O-galloyl)glucopyranoside (13), a flavan-3-ol, (-)-epigallocatechin 3-O-gallate (16), two proanthocyanidins, catechin-(4alpha-->8)-epigallocatechin 3-O-gallate (17) and epicatechin 3-O-gallate-(4beta-->8)-epigallocatechin 3-O-gallate (18), and an anthocyanin, idaein (19). Compounds 14 and 15 were identified as (E)-3,5,3',4'-tetrahydroxystilbene 3-O-beta-D-(6-O-galloyl)glucopyranoside and (E)-3,5,4'-trihydroxystilbene 3-O-beta-D-(6-O-galloyl)glucopyranoside, respectively, based on spectral and chemical data.
Miyaichi
Yukinori
Y
Department of Pharmacognosy, Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, Japan. y-miyaichi@hokuriko-u.ac.jp
Nunomura
Norihisa
N
Kawata
Yukio
Y
Kizu
Haruhisa
H
Tomimori
Tsuyoshi
T
Watanabe
Takashi
T
Takano
Akihito
A
Malla
Kuber Jung
KJ
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D004121:Dimethyl Sulfoxide; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008518:Medicine, East Asian Traditional; D009390:Nepal; D010946:Plants, Medicinal / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*; D012997:Solvents; D013055:Spectrophotometry, Infrared; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification
D003374:Coumarins; D012997:Solvents; D013267:Stilbenes; D004121:Dimethyl Sulfoxide