title: Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot.
abstract: A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 microg/ml and the IC50 value was 50 microg/ml.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University. miyazawa@apch.kindai.ac.jp
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Miyazawa
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Utsunomiya
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Inada
authors.forename: Tomoki
authors.initials: T
authors.lastname: Yamada
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Okuno
authors.forename: Harunari
authors.initials: H
authors.lastname: Tanaka
authors.forename: Masae
authors.initials: M
authors.lastname: Tatematsu
mesh_terms: D005663:Furans / Q000737:chemistry / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects*; D017705:Lignans / Q000737:chemistry / Q000494:pharmacology*; D000432:Methanol; D027861:Prunus / Q000737:chemistry*; D012997:Solvents; D013055:Spectrophotometry, Infrared; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D005663:Furans; D017705:Lignans; D012997:Solvents; C042192:syringaresinol; D000432:Methanol