title: Prevalence of negative chest radiography results in the emergency department patient with decompensated heart failure.
abstract: OBJECTIVE
  Although chest radiography is quick and inexpensive, previous research suggests that it is often misleading in emergency department (ED) patients with decompensated heart failure, resulting in misdiagnosis and inappropriate treatment. This study determines the rate of negative chest radiography results in patients found to have disease and the potential contribution of negative findings to a diagnosis discordant with heart failure by an emergency physician.
  
  
  METHODS
  We used data from the Acute Decompensated Heart Failure National Registry (ADHERE), a registry of patients with a primary hospital discharge diagnosis of heart failure. We compared initial ED admitting diagnosis to the criterion standard of a hospital discharge diagnosis of heart failure and related these to radiographic findings of heart failure (interstitial edema, pulmonary edema, or vascular congestion, as determined by a staff radiologist) for patients first treated in the ED. The proportion of patients with a non-heart failure ED diagnosis and the diagnostic sensitivity of radiographic findings of heart failure are calculated.
  
  
  RESULTS
  There were 85,376 patients with chest radiograph results and an ED admitting diagnosis. Overall, there were 15,937 patients with no signs of congestion on ED chest radiography, giving a negative rate of 18.7% (95% confidence interval [CI] 18.4% to 18.9%). The proportion of patients with an ED non-heart failure admitting diagnosis was higher in patients with a negative chest radiograph result (23.3%; 95% CI 22.6% to 23.9%) than in patients with a positive chest radiograph result (13.0%; 95% CI 12.7% to 13.2%).
  
  
  CONCLUSIONS
  Approximately 1 of every 5 patients admitted from the ED with acute decompensated heart failure had no signs of congestion on chest radiography. Patients lacking signs of congestion on ED chest radiography were more likely to have an ED non-heart failure diagnosis than patients with signs of congestion. Clinicians should not rule out heart failure in patients with no radiographic signs of congestion.
authors.affiliation: Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA. sean.collins@uc.edu
authors.forename: Sean P
authors.initials: SP
authors.lastname: Collins
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Lindsell
authors.forename: Alan B
authors.initials: AB
authors.lastname: Storrow
authors.forename: William T
authors.initials: WT
authors.lastname: Abraham
mesh_terms: D000368:Aged; D015331:Cohort Studies; D004635:Emergency Medicine / Q000379:methods*; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D005188:False Negative Reactions; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000453:epidemiology; D006801:Humans; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D015995:Prevalence; D011859:Radiography; D012042:Registries; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014481:United States / Q000453:epidemiology