The EROP-Moscow oligopeptide database.
Natural oligopeptides may regulate nearly all vital processes. To date, the chemical structures of nearly 6000 oligopeptides have been identified from >1000 organisms representing all the biological kingdoms. We have compiled the known physical, chemical and biological properties of these oligopeptides--whether synthesized on ribosomes or by non-ribosomal enzymes--and have constructed an internet-accessible database, EROP-Moscow (Endogenous Regulatory OligoPeptides), which resides at http://erop.inbi.ras.ru. This database enables users to perform rapid searches via many key features of the oligopeptides, and to carry out statistical analysis of all the available information. The database lists only those oligopeptides whose chemical structures have been completely determined (directly or by translation from nucleotide sequences). It provides extensive links with the Swiss-Prot-TrEMBL peptide-protein database, as well as with the PubMed biomedical bibliographic database. EROP-Moscow also contains data on many oligopeptides that are absent from other convenient databases, and is designed for extended use in classifying new natural oligopeptides and for production of novel peptide pharmaceuticals.
Zamyatnin
Alexander A
AA
A.N. Bach Institute of Biochemistry, Russian Academy of Sciences, 33 Leninsky prosp., Moscow 119071, Russian Federation. aaz@inbi.ras.ru
Borchikov
Alexander S
AS
Vladimirov
Michail G
MG
Voronina
Olga L
OL
D000890:Anti-Infective Agents / Q000737:chemistry; D030562:Databases, Protein; D020407:Internet; D009031:Moscow; D009479:Neuropeptides / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry*; D036361:Peptide Hormones / Q000737:chemistry; D014118:Toxins, Biological / Q000737:chemistry; D014584:User-Computer Interface
D000890:Anti-Infective Agents; D009479:Neuropeptides; D009842:Oligopeptides; D036361:Peptide Hormones; D014118:Toxins, Biological