title: [Risk stratification in pre-hospital management of myocardial infarction with ST elevation: value of a risk score profile].
abstract: The aims of this study were to evaluate new tools of risk stratification in an unselected population of myocardial infarction (MI), usable in a pre-hospital situation, and to compare the risk profile of these patients with those of other clinical trials or myocardial infarction registries. The risk scores of death at 30 days (TIMI score and TIMI risk index) based on data available in the context of coronary emergencies, were applied to the population base of the MI observatory of myocardial infarction in the Côte d'Or (RICO). The risk profile was expressed by the smoothed graph of frequency distribution of each score. The TIMI score applied to the RICO population had a high discriminating power (c = 0.80) for mortality whereas TIMI risk index was less powerful (c = 0.57). The risk profile of the RICO population was comparable to that of InTIME II, ASSENT 2 and the NRMI with reperfusion registry. The NRMI without reperfusion and the MAGIC studies had different profiles characterised by a shift in the graph towards high risk patients. The authors conclude that risk stratification scores, like the TIMI score, are valuable tools for early triage in the management of MI patients. The risk profiles allow comparative analysis of risk levels of populations notably with respect to other registries and also with respect to randomised clinical trials.
authors.affiliation: Service de cardiologie, observatoire RICO, CHU Bocage, bd Mal de Lattre de Tassigny, Dijon. marianne.zeller@u-bourgogne.fr
authors.forename: M
authors.initials: M
authors.lastname: Zeller
authors.forename: J
authors.initials: J
authors.lastname: Ravisy
authors.forename: J C
authors.initials: JC
authors.lastname: Beer
authors.forename: Y
authors.initials: Y
authors.lastname: Laurent
authors.forename: L
authors.initials: L
authors.lastname: Janin-Manificat
authors.forename: B
authors.initials: B
authors.lastname: Cabrita
authors.forename: I
authors.initials: I
authors.lastname: L'Huillier
authors.forename: J E
authors.initials: JE
authors.lastname: Wolf
authors.forename: M
authors.initials: M
authors.lastname: Freysz
authors.forename: Y
authors.initials: Y
authors.lastname: Cottin
mesh_terms: D000368:Aged; D002986:Clinical Trials as Topic; D004562:Electrocardiography; D004632:Emergency Medical Services; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000401:mortality* / Q000628:therapy; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index