Ocular argyrosis after long-term self-application of eyelash tint.
OBJECTIVE
To report cases of ocular argyrosis that developed after long-term self-application of commercially available eyelash tint.


METHODS
Observational case series.


METHODS
Case review, clinicopathologic analysis, and literature review.


RESULTS
Three patients developed ocular argyrosis after the long-term self-application of Revlon Professional Roux Lash and Brow Tint (Colomer USA Corp, New York, New York, USA). Clinical evaluation revealed various degrees of silver deposition on the upper eyelid, lid margin, caruncle and conjunctiva, and diffuse Descemet's membrane deposits. In one case, histologic examination demonstrated silver deposition in the basement membrane and superficial substantia propria of the conjunctiva.


CONCLUSIONS
Argyrosis can occur after long-term application of readily available eyelash tints, and the deposition of silver may be permanent. In certain circumstances, conjunctival argyrosis may simulate benign and malignant lesions, including conjunctival melanoma. These products should only be applied by trained cosmetologists.
Gallardo
Mark J
MJ
Department of Ophthalmology, University of Texas Health Sciences Center, San Antonio, TX, USA.
Randleman
J Bradley
JB
Price
Kristina M
KM
Johnson
Daniel A
DA
Acosta
Sharon
S
Grossniklaus
Hans E
HE
Stulting
R Doyle
RD
D000368:Aged; D001129:Argyria / Q000209:etiology* / Q000473:pathology; D003229:Conjunctival Diseases / Q000209:etiology* / Q000473:pathology; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D003886:Descemet Membrane / Q000187:drug effects; D005140:Eyelashes; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006202:Hair Dyes / Q000009:adverse effects*; D006801:Humans; D012646:Self Administration
D006202:Hair Dyes