title: Escherichia coli K-12: a cooperatively developed annotation snapshot--2005.
abstract: The goal of this group project has been to coordinate and bring up-to-date information on all genes of Escherichia coli K-12. Annotation of the genome of an organism entails identification of genes, the boundaries of genes in terms of precise start and end sites, and description of the gene products. Known and predicted functions were assigned to each gene product on the basis of experimental evidence or sequence analysis. Since both kinds of evidence are constantly expanding, no annotation is complete at any moment in time. This is a snapshot analysis based on the most recent genome sequences of two E.coli K-12 bacteria. An accurate and up-to-date description of E.coli K-12 genes is of particular importance to the scientific community because experimentally determined properties of its gene products provide fundamental information for annotation of innumerable genes of other organisms. Availability of the complete genome sequence of two K-12 strains allows comparison of their genotypes and mutant status of alleles.
authors.affiliation: Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA. mriley@mbl.edu
authors.forename: Monica
authors.initials: M
authors.lastname: Riley
authors.forename: Takashi
authors.initials: T
authors.lastname: Abe
authors.forename: Martha B
authors.initials: MB
authors.lastname: Arnaud
authors.forename: Mary K B
authors.initials: MK
authors.lastname: Berlyn
authors.forename: Frederick R
authors.initials: FR
authors.lastname: Blattner
authors.forename: Roy R
authors.initials: RR
authors.lastname: Chaudhuri
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Glasner
authors.forename: Takashi
authors.initials: T
authors.lastname: Horiuchi
authors.forename: Ingrid M
authors.initials: IM
authors.lastname: Keseler
authors.forename: Takehide
authors.initials: T
authors.lastname: Kosuge
authors.forename: Hirotada
authors.initials: H
authors.lastname: Mori
authors.forename: Nicole T
authors.initials: NT
authors.lastname: Perna
authors.forename: Guy
authors.initials: G
authors.lastname: Plunkett
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Rudd
authors.forename: Margrethe H
authors.initials: MH
authors.lastname: Serres
authors.forename: Gavin H
authors.initials: GH
authors.lastname: Thomas
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Thomson
authors.forename: David
authors.initials: D
authors.lastname: Wishart
authors.forename: Barry L
authors.initials: BL
authors.lastname: Wanner
mesh_terms: D003226:Congresses as Topic; D003299:Cooperative Behavior; D048168:Escherichia coli K12 / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics*; D016680:Genome, Bacterial; D023281:Genomics; D009626:Terminology as Topic
chemical_list: D029968:Escherichia coli Proteins