title: Genomic regulation of Hox collinearity.
abstract: During vertebrate limb development, Hoxd genes are transcribed in two temporal phases; an early wave controls growth and polarity up to the forearm and a late wave patterns the digits. In this issue of Developmental Cell, Tarchini and Duboule (2006) report that two opposite regulatory modules direct early collinear expression of Hoxd genes.
authors.affiliation: Department of Zoology, University of Florida, P.O. Box 118525, Gainesville, Florida 32611, USA.
authors.forename: Renata
authors.initials: R
authors.lastname: Freitas
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Cohn
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000502:physiology; D005121:Extremities / Q000196:embryology; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox / Q000235:genetics / Q000502:physiology*; D023281:Genomics; D018398:Homeodomain Proteins / Q000235:genetics / Q000502:physiology*; D051379:Mice
chemical_list: D018398:Homeodomain Proteins