More than 1 + 2 in mRNA decapping.
Decapping of messenger RNA was thought to involve a complex of only Dcp1 and Dcp2, but new data suggest that a larger multisubunit decapping complex exists in mammals. The larger complex includes a protein that facilitates the association of the two Dcp proteins and can be recruited by specific factors that promote mRNA decay.
Bail
Sophie
S
Kiledjian
Megerditch
M
D000818:Animals; D004722:Endoribonucleases / Q000378:metabolism*; D006801:Humans; D046912:Multiprotein Complexes / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D012315:RNA Caps / Q000235:genetics / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000378:metabolism*
D046912:Multiprotein Complexes; D012315:RNA Caps; D016601:RNA-Binding Proteins; D004722:Endoribonucleases