title: Videocapillaroscopic alterations in erythematotelangiectatic rosacea.
abstract: BACKGROUND
  Rosacea is a common chronic dermatosis that involves the cutaneous microvasculature of the face. There are no objective measures for assessing the severity of erythematotelangiectatic rosacea.
  
  
  OBJECTIVE
  Our purpose was to characterize and provide objective measures of vessel changes in erythematotelangiectatic rosacea by videocapillaroscopy.
  
  
  METHODS
  We compared 30 patients with erythematotelangiectatic rosacea with 30 age- and sex-matched patients with facial seborrheic dermatitis and 30 healthy control subjects. Videocapillaroscopy was performed both on the cheeks and on the nailfold region. The analyzed parameters of the face were morphological (background color, vessel irregularities) and quantitative (polygonal net perimeter, telangiectasia, and vessel diameters).
  
  
  RESULTS
  Characteristic alterations of skin vessels were observed in facial rosacea, with a pattern distinct from that of facial seborrheic dermatitis. In particular, rosacea showed neoangiogenesis and significantly larger polygons (13.21 +/- 3 vs 7.8 +/- 3 mm; mean +/- standard deviation, P < .001), more prominent telangiectases (267.8 +/- 108 vs 118.2 +/- 35 microm; P < .001) and larger mean vessel diameter (46.71 +/- 9 vs 24 +/- 10 microm; P < .001) compared with seborrheic dermatitis. Seborrheic dermatitis displayed more polygon irregularities and vessel tortuosity. In contrast, no differences were found in the nailfold region.
  
  
  CONCLUSIONS
  Vessel irregularities and overall erythema may be difficult to quantify.
  
  
  CONCLUSIONS
  Videocapillaroscopy may represent a valid adjunctive method in the early diagnosis and measurement of erythematotelangiectatic rosacea.
authors.affiliation: Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy. paolo.rosina@univr.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Rosina
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Zamperetti
authors.forename: Andrea
authors.initials: A
authors.lastname: Giovannini
authors.forename: Carlo
authors.initials: C
authors.lastname: Chieregato
authors.forename: Giampiero
authors.initials: G
authors.lastname: Girolomoni
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D012628:Dermatitis, Seborrheic / Q000473:pathology; D004890:Erythema / Q000473:pathology*; D005145:Face / Q000098:blood supply; D005260:Female; D006801:Humans; D008297:Male; D020678:Microscopic Angioscopy; D018715:Microscopy, Video; D008875:Middle Aged; D009262:Nails / Q000098:blood supply; D009389:Neovascularization, Pathologic / Q000473:pathology; D012393:Rosacea / Q000473:pathology*; D012720:Severity of Illness Index; D012867:Skin / Q000098:blood supply / Q000473:pathology; D013684:Telangiectasis / Q000473:pathology*