title: Long-term outcomes of endoscopic repair of cerebrospinal fluid leaks and meningoencephaloceles.
abstract: BACKGROUND
  The management and surgical approach to cerebrospinal fluid (CSF) leaks and meningoencephaloceles have undergone transformation throughout the last 10 years. It is our interest to examine the long-term surgical outcome and reoccurrence rates of CSF leaks or meningoencephaloceles in patients having endoscopic surgical repair.
  
  
  METHODS
  We performed a retrospective evaluation of 50 patients that underwent endoscopic surgical repair of a CSF leak, meningoencephalocele, or both, between September 1985 and October 2003.
  
  
  RESULTS
  Cumulatively, reoccurrence rates were 15% (7/47) among the CSF leak patients with an average time frame for reoccurrence ranging from 1 to 25 months (average, 7 months). Patients with meningoencephaloceles had an overall reoccurrence rate of 8% (1/13). In addition, a Medline search on CSF leaks and meningoencephaloceles provided the names of 32 authors that have studied outcomes of endoscopic surgical repair. Of the 151 patients still followed in the 5- to 10-year postoperative group, there were 37 recurrences of CSF leaks and 5 reoccurrences of the meningoencephaloceles with a total recurrence rate of 27% (37 + 5/151). Of the 19 patients still followed in the >10-year postoperative group, there were three reoccurrences of CSF leaks and no reoccurrences of meningoencephaloceles, giving a reoccurrence rate of 16% (3 + 0/19).
  
  
  CONCLUSIONS
  Based on our cumulative results, a reoccurrence of a CSF leak or meningoencephalocele after endoscopic repair will occur within the first 2 years postoperatively. Once patients pass these postoperative time frames they are relatively free of reoccurrence from this very effective surgical management. Endoscopic repair results are better than craniotomy with much less morbidity.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Tulane University, New Orleans, Louisiana, USA.
authors.forename: Jodi
authors.initials: J
authors.lastname: Zuckerman
authors.forename: James A
authors.initials: JA
authors.lastname: Stankiewicz
authors.forename: James M
authors.initials: JM
authors.lastname: Chow
mesh_terms: D000328:Adult; D000368:Aged; D002555:Cerebrospinal Fluid; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008591:Meningomyelocele / Q000601:surgery*; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome