title: [Langerhans' cell histiocytosis of the mandible in infant: report of one case].
abstract: Langerhans' cell histiocytosis of the mandible is a rare disease in infant. This article reported a case of Langerhans' cell histiocytosis of mandible in a 2-year old female child. The clinical manifestation, radiographic characteristics, pathologic diagnosis, differential diagnosis and treatment were discussed. It is concluded that Langerhans' cell histiocytosis of the mandible in infant is rare without typical clinical manifestation and radiographic characteristics; final diagnosis is based on pathological examination with the characteristic hyperplasia of Langerhans' cell; immunohistochemistry examination of S-100 and CD1a are useful for diagnosis and differential diagnosis. Surgical resection with close postoperative follow-up is suggested as the main treatment for this disease.
authors.affiliation: Department of Pathology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Lai-ping
authors.initials: LP
authors.lastname: Zhong
authors.forename: Li-rong
authors.initials: LR
authors.lastname: Chen
authors.forename: Guan-fu
authors.initials: GF
authors.lastname: Chen
authors.forename: Fei-yun
authors.initials: FY
authors.lastname: Ping
mesh_terms: D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D007223:Infant; D008334:Mandible / Q000473:pathology*