title: Does yeast shmooing mean a commitment to apoptosis?
abstract: Treatment of yeast Saccharomyces cerevisiae with alpha-pheromone has been reported to lead to massive apoptosis of cells finding no conjugation partner [Severin FF, Hyman AA. Pheromone induces programmed cell death in S. cerevisiae. Curr Biol 2002;12:R233-5]. We report here that this effect is not common in yeast. Using different yeast strains, we demonstrate that identical treatment results in a low mortality even after prolonged treatment with the pheromone. These findings are followed by a general discussion of the biological relevance of apoptosis in yeast.
authors.affiliation: Department of Biochemistry and Cell Biology, University of Rzeszów, ul. Rejtana 16C, 35-959 Rzeszów, Poland.
authors.forename: Renata
authors.initials: R
authors.lastname: Zadrag
authors.forename: Leszek
authors.initials: L
authors.lastname: Wojnar
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Bartosz
authors.forename: Tomasz
authors.initials: T
authors.lastname: Biliński
mesh_terms: D017209:Apoptosis / Q000187:drug effects*; D000072235:Mating Factor; D010455:Peptides / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D013997:Time Factors; D015003:Yeasts / Q000166:cytology* / Q000187:drug effects* / Q000502:physiology
chemical_list: D010455:Peptides; D017382:Reactive Oxygen Species; D000072235:Mating Factor