title: Perfusion studies of steady flow in poroelastic myocardium tissue.
abstract: The behaviour of the heart has always elicited interest and particularly the study of its myocardium, as 5-10% of the blood pumped by the heart is passed through the coronary arteries to the myocardium itself. An in-depth investigation of the myocardium behaviour is useful. The present work aims to investigate how myocardium perfusion is influenced by myocardial stress and diseased states, and in general by LV pumping abnormalities. LV myocardial perfusion can then serve as a possible index of the capacity of the LV to respond to its work demand, and thus of the risk of heart failure. The poroelastic analysis of the myocardium based on finite element method (FEM) for regional perfusion through a rectangular element with various physiological ranges of loading conditions was studied.
authors.affiliation: Nanyang Technological University, School of Mechanical and Aerospace Engineering, Singapore, 639798, Singapore. mykng@ntu.edu.sg
authors.forename: E Y K
authors.initials: EY
authors.lastname: Ng
authors.forename: D N
authors.initials: DN
authors.lastname: Ghista
authors.forename: R C
authors.initials: RC
authors.lastname: Jegathese
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D003198:Computer Simulation; D003326:Coronary Circulation / Q000502:physiology*; D004548:Elasticity; D006321:Heart / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D016062:Porosity; D011673:Pulsatile Flow / Q000502:physiology*