title: Photophysical properties of diphenyl-2,3-dihydroxychlorin and diphenylchlorin.
abstract: The photophysical properties of 5,15-diphenyl-2,3-dihydroxychlorin (DPCOH) and 5,15-diphenyl-chlorin (DPC) in organic solution were studied. Absorption, fluorescence, triplet state and photobleaching experiments are reported. The ground states of both compounds show strong absorbance in red region (lambda = 638 nm, epsilon = 35,000 M(-1) cm(-1) and lambda = 645 nm, epsilon = 42,000 M(-1) cm(-1), respectively) and the singlet excited states show low fluorescence quantum yields of 0.0802 and 0.150 in benzene and the lifetimes are 7.38 and 10.18 ns, respectively. Absorption spectra of the triplet states were also measured and they have nearly the same triplet state lifetimes of 53 micros (DPCOH) and 50 micros (DPC). The triplet quantum yields are 0.82 and 0.75, respectively. The data of photobleaching quantum yields show that the presence of oxygen does not significantly affect the photobleaching. All the results demonstrate that both diphenylchlorines are good candidates for second-generation photosensitizer in photodynamic therapy.
authors.affiliation: CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.
authors.forename: Xufeng
authors.initials: X
authors.lastname: Shan
authors.forename: Tianyu
authors.initials: T
authors.lastname: Wang
authors.forename: Shayu
authors.initials: S
authors.lastname: Li
authors.forename: Lanying
authors.initials: L
authors.lastname: Yang
authors.forename: Limin
authors.initials: L
authors.lastname: Fu
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Yang
authors.forename: Zhengping
authors.initials: Z
authors.lastname: Wang
authors.forename: Jin Shi
authors.initials: JS
authors.lastname: Ma
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010777:Photochemistry; D017319:Photosensitizing Agents / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: C509069:5,15-diphenylchlorin; D001713:Biphenyl Compounds; D017319:Photosensitizing Agents; D011166:Porphyrins; D012996:Solutions; C435783:diphenyl-2,3-dihydroxychlorin