[Changes in liver and in some organs of immune system of animals exposed to twenty-four-hour illumination].
The aim of this research was to study the morpho-functional organization of liver and some organs of immune system in animals exposed to continous twenty-four-hour illumination (CI) for 14 days. Using the methods of light and electron microscopy and morphometric analysis of histological preparations, liver and regional lymph nodes (hepatic in rats and iliac in mice) were studied. It was found that CI resulted in a state of dyschronosis, which was structurally manifested by the changes of diurnal variations of morphometric parameters of liver and its draining lymph nodes, disturbances of hemo- and lymphocirculation, destruction of cellular membranes. Response of central and peripheral organs of immune system to CI included the changes of diurnal variations of blast forms and mature lymphocytes, that was also indicative of dyschronosis development.
Michurina
S V
SV
Shurlygina
A V
AV
Belkin
A D
AD
Vakulin
G M
GM
Verbitskaia
L V
LV
Trufakin
V A
VA
D000818:Animals; D021081:Chronobiology Disorders / Q000276:immunology / Q000473:pathology*; D007107:Immune System / Q000502:physiology / Q000648:ultrastructure; D008027:Light; D008099:Liver / Q000503:physiopathology / Q000648:ultrastructure*; D008198:Lymph Nodes / Q000503:physiopathology / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D051381:Rats