title: Application of olefin cross-metathesis to the synthesis of biologically active natural products.
abstract: An overview of the use of olefin cross-metathesis in the synthesis of biologically active natural products is presented. The diverse examples are organized according to the outcome of the olefin constructed by the cross-metathesis reaction: this olefin can be either present in the final product, reduced, engaged in other transformations, or involved in tandem processes.
authors.affiliation: Laboratoire de Synthèse Organique, UMR CNRS 7652, Ecole Polytechnique, DCSO, 91128 Palaiseau, France. joelle.prunet@polytechnique.fr
authors.forename: Joëlle
authors.initials: J
authors.lastname: Prunet
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D008982:Molybdenum / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001688:Biological Products; D006571:Heterocyclic Compounds; D047028:Macrocyclic Compounds; D012428:Ruthenium; D008982:Molybdenum