Erythema elevatum diutinum as a first clinical manifestation for diagnosing HIV infection: case history.
BACKGROUND
Erythema elevatum diutinum is a chronic and rare dermatosis that is considered to be a variant of leukocytoclastic vasculitis. It is probably mediated by immune complexes. It is generally associated with autoimmune, neoplastic and infectious processes. Recently, it has been added to the group of specific dermatoses that are associated with HIV.


METHODS
We report on the case of a patient who had erythema elevatum diutinum as the first clinical evidence for diagnosing HIV infection. Dapsone was used in the treatment of this patient, and partial regression of the lesions was achieved within 15 days, even before anti-retroviral therapy was prescribed.


CONCLUSIONS
When there is a diagnosis of erythema elevatum diutinum, HIV infection should be investigated, especially in atypical and exacerbated clinical manifestations.
Rover
Patrícia Accioni
PA
Dermatology Department, Hospital Universitdrio Celso Pierro (HMCP), Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, Brazil. parover@ig.com.br
Bittencourt
Caroline
C
Discacciati
Mariana Pimenta
MP
Zaniboni
Mariana Colombini
MC
Arruda
Lúcia Helena de Fávaro
LH
Cintra
Maria Letícia
ML
D000890:Anti-Infective Agents / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004890:Erythema / Q000188:drug therapy / Q000209:etiology*; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
D000890:Anti-Infective Agents; D003622:Dapsone