Recent advances of protein microarrays.
Technological innovations and novel applications have greatly advanced the field of protein microarrays. Over the past two years, different types of protein microarrays have been used for serum profiling, protein abundance determinations, and identification of proteins that bind DNA or small compounds. However, considerable development is still required to ensure common quality standards and to establish large content repertoires. Here, we summarize applications available to date and discuss recent technological achievements and efforts on standardization.
Hultschig
Claus
C
Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, D-14195 Berlin, Germany.
Kreutzberger
Jürgen
J
Seitz
Harald
H
Konthur
Zoltán
Z
Büssow
Konrad
K
Lehrach
Hans
H
D000818:Animals; D000906:Antibodies / Q000737:chemistry / Q000276:immunology; D000937:Antigen-Antibody Reactions; D006801:Humans; D007103:Immobilization; D040081:Protein Array Analysis / Q000379:methods* / Q000592:standards; D012680:Sensitivity and Specificity
D000906:Antibodies