Congenital subcutaneous dendritic cell rich lymphoepithelial hamartoma.
We present the clinical, radiologic, histologic, immunohistochemical, and ultrastructural characteristics of a congenital pretibial subcutaneous lesion composed of a mixture of T and B cells, epithelial cells, and dendritic cells, probably representing a hamartoma. After total removal, there has been no recurrence. The prominent dendritic component of this lesion, demonstrated immunohistochemically and ultrastructurally, separates the lesion from cutaneous lymphadenoma and other adnexal tumors.
Craver
Randall
R
Children's Hospital of New Orleans, Department of Pathology, Louisiana State University Health Science Center, New Orleans, 70118, USA. rcrave@lsuhsc.edu
Ward
Kenneth
K
Heinrich
Stephen
S
D001402:B-Lymphocytes / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure; D003560:Cysts / Q000473:pathology; D003713:Dendritic Cells / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D003937:Diagnosis, Differential; D004847:Epithelial Cells / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008067:Lipoma / Q000473:pathology; D008297:Male; D046529:Microscopy, Electron, Transmission; D018294:Neoplasms, Adnexal and Skin Appendage / Q000473:pathology; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D013601:T-Lymphocytes / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure