title: Evaluation of left ventricular systolic function using automated angle-independent motion tracking of mitral annular displacement.
abstract: Determination of ejection fraction (EF) in clinical practice typically involves manual tracing of endocardial borders. This method is time-intensive and highly dependent on image quality. Mitral annular displacement (MAD) has been shown to correlate well with EF. Previously, this method involved tedious analysis of M-mode tracings. We developed and studied a new technique that is ultrasound beam angle-independent for automated detection of MAD, based on a tissue tracking algorithm. A regression formula was derived in a study group to predict EF from MAD measurements and tested prospectively in a separate group of patients. We found that our technique provides accurate, ultra-fast estimation of EF with lower inter- and intraobserver variability when compared with manually traced biplane EF.
authors.affiliation: Department of Medicine, University of Chicago, Chicago, Illinois, USA. jdecara@medicine.bsd.uchicago.edu
authors.forename: Jeanne M
authors.initials: JM
authors.lastname: DeCara
authors.forename: Eran
authors.initials: E
authors.lastname: Toledo
authors.forename: Ivan S
authors.initials: IS
authors.lastname: Salgo
authors.forename: Georgeanne
authors.initials: G
authors.lastname: Lammertin
authors.forename: Lynn
authors.initials: L
authors.lastname: Weinert
authors.forename: Roberto M
authors.initials: RM
authors.lastname: Lang
mesh_terms: D000328:Adult; D000465:Algorithms; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D009068:Movement; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D013599:Systole; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*