title: TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruzi.
abstract: TcruziDB (http://TcruziDB.org) is an integrated post-genomics database for the parasitic organism, Trypanosoma cruzi, the causative agent of Chagas' disease. TcruziDB was established in 2003 as a flat-file database with tools for mining the unannotated sequence reads and preliminary contig assemblies emerging from the Tri-Tryp genome consortium (TIGR/SBRI/Karolinska). Today, TcruziDB houses the recently published assembled genomic contigs and annotation provided by the genome consortium in a relational database supported by the Genomics Unified Schema (GUS) architecture. The combination of an annotated genome and a relational architecture has facilitated the integration of genomic data with expression data (proteomic and EST) and permitted the construction of automated analysis pipelines. TcruziDB has accepted, and will continue to accept the deposition of genomic and functional genomic datasets contributed by the research community.
authors.affiliation: Instituto de Investigaciones Biotecnológicas, Universidad de San Martín San Martín, B 1650 KNA, Buenos Aires, Argentina.
authors.forename: Fernán
authors.initials: F
authors.lastname: Agüero
authors.forename: Wenlong
authors.initials: W
authors.lastname: Zheng
authors.forename: D Brent
authors.initials: DB
authors.lastname: Weatherly
authors.forename: Pablo
authors.initials: P
authors.lastname: Mendes
authors.forename: Jessica C
authors.initials: JC
authors.lastname: Kissinger
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D015870:Gene Expression; D018503:Genome, Protozoan; D023281:Genomics; D020407:Internet; D015800:Protozoan Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012984:Software; D018511:Systems Integration; D014349:Trypanosoma cruzi / Q000235:genetics* / Q000378:metabolism; D014584:User-Computer Interface
chemical_list: D015800:Protozoan Proteins