Biomarkers in croakers Micropogonias furnieri (Teleostei: Sciaenidae) from polluted and non-polluted areas from the Patos Lagoon estuary (Southern Brazil): evidences of genotoxic and immunological effects.
Biomarkers of exposure and effect of pollutants were analyzed in croakers Micropogonias furnieri (Teleostei: Sciaenidae) captured in winter and summer in a polluted and in a non-polluted site at the Patos Lagoon estuary (Southern Brazil). Catalase and glutathione S-transferase activities (exposure biomarkers) and lipid peroxidation (effect biomarker) were analyzed in liver samples. Other two effect biomarkers were also studied: blood cells DNA damage (through comet assay and micronucleus test) and respiratory burst measurements. In a broad view, results point to an important seasonal variation of the biochemical biomarkers analyzed. However, data obtained clearly indicate that croakers collected in winter at the polluted site were subjected to a level of clastogenic agents sufficient to generate irreversible genetic damages (mutations) and impair the fish immune system.
Amado
Lílian Lund
LL
Programa de Pós-Graduação em Oceanografia Biológica, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil.
da Rosa
Carlos Eduardo
CE
Leite
Alice Meirelles
AM
Moraes
Loraine
L
Pires
Wagner Vaz
WV
Pinho
Grasiela L Leães
GL
Martins
Camila Martinez Gaspar
CM
Robaldo
Ricardo Berteaux
RB
Nery
Luis Eduardo Maia
LE
Monserrat
José Maria
JM
Bianchini
Adalto
A
Martinez
Pablo Elias
PE
Geracitano
Laura Alicia
LA
D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D001773:Blood Cells / Q000187:drug effects; D001938:Brazil; D002374:Catalase / Q000187:drug effects / Q000378:metabolism; D004249:DNA Damage / Q000187:drug effects / Q000502:physiology*; D004781:Environmental Exposure; D004784:Environmental Monitoring; D005393:Fish Diseases / Q000139:chemically induced; D005982:Glutathione Transferase / Q000187:drug effects / Q000378:metabolism; D007154:Immune System Diseases / Q000139:chemically induced / Q000662:veterinary; D015227:Lipid Peroxidation / Q000187:drug effects; D008668:Metallothionein / Q000032:analysis; D010473:Perciformes / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D016897:Respiratory Burst / Q000187:drug effects; D012621:Seasons; D012623:Seawater / Q000737:chemistry; D014876:Water Pollution / Q000009:adverse effects*
D015415:Biomarkers; D008668:Metallothionein; D002374:Catalase; D005982:Glutathione Transferase