Incidence and mortality risk of congestive heart failure in atrial fibrillation patients: a community-based study over two decades.
OBJECTIVE
We sought to determine whether the incidence of and survival following congestive heart failure (CHF) in patients with atrial fibrillation (AF) have changed over time.


RESULTS
Olmsted County, Minnesota residents diagnosed with first AF during 1980-2000 were identified and followed in medical records to 2004. The trends of incidence and survival of CHF over time were assessed. Of the 3288 subjects (mean age 71+/-15 years) diagnosed with first AF and without CHF prior to or at AF diagnosis, 790 (24%) developed a first CHF during a mean follow-up of 6.1+/-5.2 years (unadjusted incidence, 44 per 1000 person years). Age- and sex-adjusted CHF incidence was unrelated to calendar year of AF diagnosis (P = 0.86). The age- and sex-adjusted mortality risk following CHF was higher than that in patients without CHF (hazard ratio 3.4, 95% confidence interval 3.1-3.8, P < 0.0001). There were no detectable changes over time with respect to the absolute (P = 0.94) or the relative (P = 0.68) mortality risk after CHF diagnosis.


CONCLUSIONS
In this study spanning two decades, there appeared to have been no significant reduction in terms of the incidence and mortality risk of CHF following first AF diagnosis.
Miyasaka
Yoko
Y
Division of Cardiovascular Disease and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Barnes
Marion E
ME
Gersh
Bernard J
BJ
Cha
Stephen S
SS
Bailey
Kent R
KR
Abhayaratna
Walter
W
Seward
James B
JB
Iwasaka
Toshiji
T
Tsang
Teresa S M
TS
D000368:Aged; D001281:Atrial Fibrillation / Q000150:complications / Q000401:mortality*; D004812:Epidemiologic Methods; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000401:mortality*; D006801:Humans; D008297:Male; D008910:Minnesota / Q000453:epidemiology; D009026:Mortality / Q000639:trends; D011379:Prognosis; D017678:Sex Distribution