[Interleukin-6 as a marker of the activity of a pathological process in patients with psoriasis].
71 patients with psoriasis have been observed. Interleukin-6 and its receptor levels in blood serum have been determined by means of immune-enzyme analysis. Patients have received zonal ultraviolet irradiation and 0.1% methylprednisolone aceponatatis ointment. The level of Interleukin-6 and its receptor levels in blood serum were established increased in psoriatic patients. Interleukin-6 level in blood serum correlates with psoriasis area and severity index and may be used as an activity rate of pathological process. Complex treatment with zonal ultraviolet irradiation and methylprednisolone aceponatatis proved to be effective and normalized indices of Interleukin-6 and its receptor in blood serum of patients with psoriasis.
Koliadenko
V H
VH
Chernyshov
P V
PV
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001782:Blood Donors; D015331:Cohort Studies; D003131:Combined Modality Therapy; D006801:Humans; D015850:Interleukin-6 / Q000097:blood* / Q000235:genetics; D008297:Male; D008775:Methylprednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D011701:PUVA Therapy; D011565:Psoriasis / Q000097:blood* / Q000188:drug therapy / Q000473:pathology*; D019947:Receptors, Interleukin-6 / Q000097:blood; D011994:Recombinant Proteins / Q000097:blood; D012720:Severity of Illness Index
D015415:Biomarkers; D015850:Interleukin-6; D019947:Receptors, Interleukin-6; D011994:Recombinant Proteins; C078007:methylprednisolone aceponate; D008775:Methylprednisolone