title: [Kaposi' s sarcoma. A series of 65 cases].
abstract: Kaposi sarcoma (SK) is characterized by proliferation of vascular and spindle-shaped cells with variable clinical presentations. The association with AIDS modifies the profile of this disease. The pathophysiology seems to be based on the major role HHV-8. The goal of this work was to specify the profile of this disease in our region through a retrospective study of 65 cases of SK over a 23-year period (1981-2003). In our series, the classic form prevailed 163 cases (96.9%)]. One patient had a secondary form due to steroid therapy and another patient had a KS associated with AIDS. A male prevalence was noticed (M/F: 2.8). Cutaneous lesions were dominated by papulo-nodular lesions (90.9%) of the lower limbs (92.3% of the cases). Mucous lesions were present in 15.4% of the cases. Therapeutic abstention was decided in 38.4%. Surgical excision was indicated in 35.4% of cases, radiotherapy in 4.6% of the cases and chemotherapy in 23% of the cases. The classic form of KS is the most frequent in our area; the other forms remaining rare.
authors.affiliation: Service de Dermatologie CHU H. Caker, Sfax, Tunisie.
authors.forename: Madiha
authors.initials: M
authors.lastname: Mseddi
authors.forename: Wafa
authors.initials: W
authors.lastname: Abdelmaksoud
authors.forename: Marrekchi
authors.initials: M
authors.lastname: Slah
authors.forename: Jalel Meziou
authors.initials: JM
authors.lastname: Taha
authors.forename: Samir
authors.initials: S
authors.lastname: Bouassida
authors.forename: Sonia
authors.initials: S
authors.lastname: Boudaya
authors.forename: Hamida
authors.initials: H
authors.lastname: Turki
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Zahaf
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012514:Sarcoma, Kaposi / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D012737:Sex Factors