Vinylcyclobutane-cyclohexene rearrangement: theoretical exploration of mechanism and relationship to the Diels-Alder potential surface.
[graph: see text] The vinylcyclobutane-cyclohexene rearrangement has been studied computationally with density functional theory and complete active space SCF calculations. The rearrangement proceeds through a diradical that exists on a very flat potential energy surface. Transition structures for conformational processes, only slightly higher in energy than the minimum energy reaction path, account for the stereochemistries of products observed in the thermal rearrangements of vinylcyclobutane derivatives. The connection of this rearrangement to the Diels-Alder reaction of butadiene with ethylene is discussed.
Northrop
Brian H
BH
Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA.
Houk
K N
KN