title: Palatal fistula repair using acellular dermal matrix: the University of Florida experience.
abstract: Palatal fistulas represent a challenging problem for surgeons caring for patients with cleft palate. The purpose of this study was to examine the rate of fistula closure using conventional surgical techniques (Group 1) versus a newer technique (Group 2) employing the use of acellular dermal matrix (AlloDerm). We reviewed the charts of all patients who underwent palatal fistula repair between July 1994 and February 2005. The surgical techniques in Group 1 varied and were considered a historical control. In the second group, a piece of dermal matrix was interposed between the nasal and oral mucoperiosteum after closure of these layers. The primary fistula closure rate for Group 1 was 83.3% (10/12 patients). Fistula closure was obtained in 100% of the patients in Group 2. There were no complications noted other that the failure of the 2 patients in Group 1. The use of AlloDerm in palatal fistula repair has reduced our failure rate from 16.7% to 0%. The use of AlloDerm during palatal fistula repair is safe, effective over time, and has the potential to reduce palatal fistula recurrence rates.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610-0286, USA. steelmh@surgery.ufl.edu
authors.forename: Matthew H
authors.initials: MH
authors.lastname: Steele
authors.forename: M Brent
authors.initials: MB
authors.lastname: Seagle
mesh_terms: D002648:Child; D002675:Child, Preschool; D002972:Cleft Palate / Q000601:surgery*; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005402:Fistula / Q000601:surgery*; D005431:Florida; D006801:Humans; D007223:Infant; D008297:Male; D014495:Universities
chemical_list: C440568:Alloderm; D003094:Collagen