Daily plasma-exchange for life-threatening class I HELLP syndrome with prevalent pulmonary involvement.
HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) is a thrombotic microangiopathy affecting a minority of women with pre-eclampsia and usually resolves after delivery. The role of plasma exchange in HELLP syndrome has to be defined. Herein is reported a case of a primipara with a class I HELLP syndrome with prevalent pulmonary involvement successfully treated with 8 consecutive plasma exchange plus corticosteroids. In class I HELLP syndrome with cardiopulmonary complications early plasma exchange could be considered a therapeutic option.
Del Fante
Claudia
C
Immunohaematology and Transfusion Service, Center for Transplant Immunology, Viale Golgi 19, IRCCS Policlinico San Matteo, 27100 Pavia, Italy. c.delfante@smatteo.pv.it
Perotti
Cesare
C
Viarengo
Gianluca
G
Gallini
Giuseppe Sala
GS
Tinelli
Carmine
C
Salvaneschi
Laura
L
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D017359:HELLP Syndrome / Q000628:therapy*; D006801:Humans; D008168:Lung / Q000473:pathology*; D010949:Plasma; D010951:Plasma Exchange / Q000379:methods*; D011225:Pre-Eclampsia / Q000628:therapy; D011247:Pregnancy; D011654:Pulmonary Edema / Q000628:therapy; D013997:Time Factors
D000305:Adrenal Cortex Hormones