title: Relapsing linear acantholytic dermatosis in a four-year-old boy.
abstract: Linear acantholytic dermatoses are a spectrum of cutaneous disorders that form a subset of linear dermatoses with distinct clinical features and histopathologically show acantholysis. The lesions may be zosteriform or follow the lines of Blaschko. This report describes a four-year-old boy who, on a follow up of two years, exhibited a relapsing acantholytic dermatosis along the lines of Blaschko. Histopathology of a representative lesion revealed epidermal acantholysis with multiple acantholytic keratinocytes with in the prickle cell layer and an absence of corp ronds and grains, consistent with features of Hailey-Hailey disease. This, to our knowledge, is the third case of relapsing linear acantholytic dermatosis reported.
authors.affiliation: Department of Dermatology, Base Hospital, Delhi Cantt-110 010, India. sarora@vsnl.com
authors.forename: Sandeep
authors.initials: S
authors.lastname: Arora
authors.forename: Gulhima
authors.initials: G
authors.lastname: Arora
authors.forename: P
authors.initials: P
authors.lastname: Ranjan
mesh_terms: D000051:Acantholysis / Q000378:metabolism / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism; D008297:Male; D012008:Recurrence