title: XYY chromosome abnormality in sexual homicide perpetrators.
abstract: In a retrospective investigation of the court reports about sexual homicide perpetrators chromosome analysis had been carried out in 13 of 166 (7.8%) men. Three men (1.8%) with XYY chromosome abnormality were found. This rate is much higher than that found in unselected samples of prisoners (0.7-0.9%) or in the general population (0.01%). The three men had shown prepubescent abnormalities, school problems, and had suffered from physical abuse. The chromosome analysis in all cases had been carried out in connection with the forensic psychiatric court report due to the sexual homicide. However, two men had earlier psychiatric referrals. All were diagnosed as sexual sadistic, showed a psychopathic syndrome or psychopathy according to the Psychopathy Checklist-Revised [Hare RD, 1991, The Hare Psychopathy Checklist-Revised, Toronto, Ontario, Canada: Multi-Health Systems]. Two were multiple murderers. Especially forensic psychiatrists should be vigilant of the possibility of XYY chromosome abnormalities in sexual offenders.
authors.affiliation: Institute of Sex Research and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. briken@uke.uni-hamburg.de
authors.forename: Peer
authors.initials: P
authors.lastname: Briken
authors.forename: Niels
authors.initials: N
authors.lastname: Habermann
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Berner
authors.forename: Andreas
authors.initials: A
authors.lastname: Hill
mesh_terms: D000328:Adult; D005555:Forensic Psychiatry; D006708:Homicide; D006801:Humans; D008297:Male; D011329:Prisoners / Q000523:psychology; D012742:Sex Offenses; D014997:XYY Karyotype / Q000235:genetics* / Q000523:psychology