Paratesticular papillary mesothelioma: a case with borderline features.
Most often, mesotheliomas involve the serosal (serous) membranes of the pleura and peritoneum. Sometimes, mesothelial proliferations are identified in other locations. On very rare occasions, a mesothelioma is found within the tunica vaginalis of the paratesticular region. We report a case of papillary mesothelioma of the tunica vaginalis in a 52-year-old man. Although this lesion had papillary structures lined by a single layer of mesothelial cells with predominantly bland nuclear and cytologic features, there was evidence of a minimal presence of mesothelial cells in the underlying stroma. This combination of benign and semimalignant characteristics can make the diagnosis of such a lesion problematic. We think that a diagnosis of "borderline papillary mesothelioma" can be considered for similar mesothelial proliferations to allow for a possible increase in diagnostic accuracy and provide an enhanced informational platform from which patients and clinicians can benefit.
Cabay
Robert J
RJ
Department of Pathology, College of Medicine, University of Illinois, Chicago, IL 60612-7335, USA. rcabay1@uic.edu
Siddiqui
Noman H
NH
Alam
Shumyle
S
D014408:Biomarkers, Tumor / Q000032:analysis; D018572:Disease-Free Survival; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013737:Testis / Q000737:chemistry / Q000473:pathology*; D016896:Treatment Outcome
D014408:Biomarkers, Tumor