title: Acquired haemophilia heralded by bleeding into the oral mucosa in a patient with bullous pemphigoid, rheumatoid arthritis, and vitiligo.
abstract: Acquired haemophilia is rare and potentially fatal, with a mortality of 20% if left untreated. There is a strong association with other autoimmune diseases. This report describes a patient with rheumatoid arthritis, vitiligo, and bullous pemphigoid where the diagnosis of acquired haemophilia was made after an extensive bleed into a bullous lesion in the buccal mucosa. This case highlights some of the potential complications of acquired haemophilia and its treatment.
authors.affiliation: Department of Haemostasis and Thrombosis, Directorate of Haematology, Leicester Royal Infirmary, Leicester LE1 5WW, UK. rakeshspatel@hotmail.com
authors.forename: R S
authors.initials: RS
authors.lastname: Patel
authors.forename: K E
authors.initials: KE
authors.lastname: Harman
authors.forename: C
authors.initials: C
authors.lastname: Nichols
authors.forename: R M
authors.initials: RM
authors.lastname: Burd
authors.forename: S
authors.initials: S
authors.lastname: Pavord
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D006467:Hemophilia A / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D009061:Mouth Mucosa; D006472:Oral Hemorrhage / Q000209:etiology*; D010391:Pemphigoid, Bullous / Q000150:complications*; D014820:Vitiligo / Q000150:complications*