title: Studies on nepalese crude drugs. XXVIII. Chemical constituents of Bhote Khair, the underground parts of Eskemukerjea megacarpum HARA.
abstract: From the underground parts of Eskemukerjea megacarpum HARA, two new stilbenes (14, 15) were isolated, together with a known coumarin, 5,7-dihydroxycoumarin (1), a tyramine derivative, trans-feruloyltyramine (2), two pyrogallol derivatives, gallic acid (3) and beta-glucogallin (4), four flavonoids, trifolin (5), hyperin (6), myricetin 3-O-beta-D-galactopyranoside (7), and myricitrin (8), five stilbenes, resveratorol (9), astringenin (10), piceid (11) astringin (12), and resveratorol 3-O-beta-D-(6-O-galloyl)glucopyranoside (13), a flavan-3-ol, (-)-epigallocatechin 3-O-gallate (16), two proanthocyanidins, catechin-(4alpha-->8)-epigallocatechin 3-O-gallate (17) and epicatechin 3-O-gallate-(4beta-->8)-epigallocatechin 3-O-gallate (18), and an anthocyanin, idaein (19). Compounds 14 and 15 were identified as (E)-3,5,3',4'-tetrahydroxystilbene 3-O-beta-D-(6-O-galloyl)glucopyranoside and (E)-3,5,4'-trihydroxystilbene 3-O-beta-D-(6-O-galloyl)glucopyranoside, respectively, based on spectral and chemical data.
authors.affiliation: Department of Pharmacognosy, Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, Japan. y-miyaichi@hokuriko-u.ac.jp
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Miyaichi
authors.forename: Norihisa
authors.initials: N
authors.lastname: Nunomura
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kawata
authors.forename: Haruhisa
authors.initials: H
authors.lastname: Kizu
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tomimori
authors.forename: Takashi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Akihito
authors.initials: A
authors.lastname: Takano
authors.forename: Kuber Jung
authors.initials: KJ
authors.lastname: Malla
mesh_terms: D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D004121:Dimethyl Sulfoxide; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008518:Medicine, East Asian Traditional; D009390:Nepal; D010946:Plants, Medicinal / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*; D012997:Solvents; D013055:Spectrophotometry, Infrared; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D003374:Coumarins; D012997:Solvents; D013267:Stilbenes; D004121:Dimethyl Sulfoxide