title: A2B adenosine receptor antagonists: recent developments.
abstract: There are pharmacological evidences that A(2B) receptors are involved in inflammatory processes, such as asthma. For this reason, many efforts has been made for identifying selective A(2B) antagonists as anti-asthmatic agents. The updated material related to this field has been rationalised and arranged in order to offer an overview of the topic.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Piazzale Europa 1, I-34127 Trieste, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Cacciari
authors.forename: Giorgia
authors.initials: G
authors.lastname: Pastorin
authors.forename: Chiara
authors.initials: C
authors.lastname: Bolcato
authors.forename: Giampiero
authors.initials: G
authors.lastname: Spalluto
authors.forename: Magdalena
authors.initials: M
authors.lastname: Bacilieri
authors.forename: Stefano
authors.initials: S
authors.lastname: Moro
mesh_terms: D058917:Adenosine A2 Receptor Antagonists; D000595:Amino Acid Sequence; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000473:pathology; D001665:Binding Sites; D015195:Drug Design; D006801:Humans; D008969:Molecular Sequence Data; D011799:Quinazolines / Q000737:chemistry / Q000378:metabolism; D014230:Triazoles / Q000737:chemistry / Q000378:metabolism; D014970:Xanthines / Q000737:chemistry / Q000378:metabolism
chemical_list: D058917:Adenosine A2 Receptor Antagonists; D018927:Anti-Asthmatic Agents; D000893:Anti-Inflammatory Agents; D011799:Quinazolines; D014230:Triazoles; D014970:Xanthines