title: Chromatographic behavior of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)ethanol on a quinidine-carbamate chiral stationary phase.
abstract: The enantioseparation of 2,2,2-trifluoro-1-(9-anthryl)ethanol on silica-bonded quinidine carbamate was examined under linear chromatographic conditions. The significant impact of nonselective adsorption on the retention was demonstrated. The influences of a polar additive in the mobile phase on the retention, the selectivity and the thermodynamic quantities of the retention were measured. A small effect of the pressure on the selectivity and on the accuracy of the thermodynamic measurements was observed.
authors.affiliation: Department of Chemistry, The University of Tennessee, 552 Buehler Hall, Knoxville, TN 37996-1600, USA.
authors.forename: Leonid
authors.initials: L
authors.lastname: Asnin
authors.forename: Gustaf
authors.initials: G
authors.lastname: Götmar
authors.forename: Georges
authors.initials: G
authors.lastname: Guiochon
mesh_terms: D000097:Acetonitriles; D000873:Anthracenes / Q000737:chemistry* / Q000302:isolation & purification*; D002219:Carbamates / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D019277:Entropy; D011802:Quinidine / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature; D013816:Thermodynamics; D014270:Trifluoroethanol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000097:Acetonitriles; D000873:Anthracenes; D002219:Carbamates; C090817:2,2,2-trifluoro-1-(9-anthryl)ethanol; D014270:Trifluoroethanol; D012822:Silicon Dioxide; D011802:Quinidine