Performing vitreous biopsy by perfluorocarbon-perfused vitrectomy.
OBJECTIVE
To evaluate the safety and efficacy of perfluorocarbon-perfused vitrectomy (PCPV) as a novel technique in obtaining a large undiluted vitreous biopsy.


METHODS
Cross-sectional interventional study.


METHODS
Patients with undiagnosed posterior uveitis scheduled for vitreous biopsy underwent PCPV. A syringe containing 5 ml of perfluorocarbon liquid (PCL) was connected to the infusion line. Aspiration of the central and superior vitreous was initiated with simultaneous infusion of the PCL.


RESULTS
Twenty eyes of 20 patients were included in this study. The mean +/- SD amount of PCL used in each eye was 4.50 +/- 0.69 ml. The volume of vitreous sample obtained in each eye was 2.25 +/- 0.413 ml. No complications occurred.


CONCLUSIONS
PCPV is a safe and effective method for obtaining large undiluted vitreous biopsy.
Quiroz-Mercado
Hugo
H
Retina Service, Asociación Para Evitar la Ceguera, Hospital Dr. Luis Sanchez Bulnes, Vicente Garcia Torres 46, San Lucas Coyoacan 04030, Coyoacan, Mexico City, Mexico. retinamex@yahoo.com
Rivera-Sempertegui
Jorge
J
Macky
Tamer A
TA
Navarro-López
Patricia
P
Griselda-Alvarez
Lidia
L
Ibarra-Ponce
Nayeli
N
Moreno-Páramo
Daniel
D
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D003430:Cross-Sectional Studies; D004322:Drainage / Q000379:methods; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D015866:Uveitis, Posterior / Q000473:pathology*; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000473:pathology*
D005466:Fluorocarbons