Idiopathic intracranial hypertension and sickle cell disease: two case reports.
METHODS
Two patients with sickle cell disease presented with headaches and visual disturbances, typical complaints of this disorder. However, prompt diagnosis of idiopathic intracranial hypertension and initiation of medical therapy lead to improved symptoms and restored vision. Ophthalmologists should consider sickle cell disease to be an independent risk factor for idiopathic intracranial hypertension when a patient is being assessed for visual disturbances.


CONCLUSIONS
Although a rare condition, idiopathic intracranial hypertension has several key signs useful in establishing a diagnosis. It is critical to recognize the warning signs and symptoms to prevent devastating ophthalmologic complications. We report the first cases of idiopathic intracranial hypertension in patients with the novel Quebec-Chori beta-chain variant of sickle cell disease.
Segal
Laura
L
Department of Ophthalmology, McGill University Health Centre, Montreal, QC.
Discepola
Marino
M
D000086:Acetazolamide / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D009765:Obesity / Q000150:complications; D011559:Pseudotumor Cerebri / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012307:Risk Factors; D014786:Vision Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014794:Visual Fields / Q000187:drug effects
D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide