title: Perspicamides A and B, quinolinecarboxylic acid derivatives from the Australian ascidian Botrylloides perspicuum.
abstract: Two novel quinoline-2-carboxylic acid derivatives, perspicamides A (2) and B (3), were isolated from the Australian ascidian Botrylloides perspicuum. Extraction of the freeze-dried ascidian with methanol and purification of the extract by C18 MPLC followed by repeated C18 HPLC yielded the new compounds 2 and 3 as well as the known compounds botryllamides A-C (4-6). The structures of 2 and 3 were determined from analysis of 2D NMR spectra.
authors.affiliation: Natural Product Discovery, Eskitis Institute, Griffith University, Brisbane, Queensland, Australia 4111.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: McKay
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Carroll
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Quinn
mesh_terms: D000818:Animals; D001315:Australia; D002264:Carboxylic Acids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011804:Quinolines / Q000737:chemistry / Q000302:isolation & purification*; D014561:Urochordata / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D011804:Quinolines; C506988:perspicamide A; C506989:perspicamide B