title: A large, erosive intraspinal and paravertebral gout tophus. Case report.
abstract: Symptomatic gout tophi of the spine are a rare but well-characterized complication of tophaceous gout. The authors report the case of a 29-year-old previously healthy man who presented with L-5 radiculopathy. Lumbar magnetic resonance (MR) imaging revealed a 4.5 x 4.5 x 2.8-cm large gout tophus mimicking a malignant spinal tumor or abscess. The tophus completely destroyed both L-4 and L-5 facet joints and the left L-4 lamina and spread epidurally from L-3 to L-5, compressing the left L-5 nerve root. There has been no similar case reported so far with respect to the extent of bone destruction. The authors describe the case history and present intraoperative, MR imaging, and histological findings.
authors.affiliation: Department of Neurosurgery, University of Regensburg, Germany. christoph.beier@gmx.de
authors.forename: Christoph P
authors.initials: CP
authors.lastname: Beier
authors.forename: Arndt
authors.initials: A
authors.lastname: Hartmann
authors.forename: Chris
authors.initials: C
authors.lastname: Woertgen
authors.forename: Alexander
authors.initials: A
authors.lastname: Brawanski
authors.forename: Ralf D
authors.initials: RD
authors.lastname: Rothoerl
mesh_terms: D000038:Abscess / Q000175:diagnosis; D000328:Adult; D003937:Diagnosis, Differential; D006073:Gout / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D011843:Radiculopathy / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis