[The possible teratogenic effect of levamisole treatment during pregnancy].
The possible teratogenic effect of levamisole treatment during pregnancy. Levamisole (Decaris) is an anthelminthic agent. The teratogenic effect of levamisole was evaluated by the analysis of a large population-based data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996. The mean gestational age was somewhat longer after levamisole treatment (adjusted t = 1.04; p = 0.30) while the mean birth weight was nearly similar in the two study groups (adjusted t = 0.36; p = 0.72). This first controlled case-control epidemiological study does not indicate a higher rate of congenital abnormalities in children born to mothers who had received oral levamisole treatment during pregnancy.
Kazy
Zoltán
Z
Genetikai Artalmak Társadalmi Megelozése Alapítvány, Budapest.
Puchó
Erzsébet
E
Czeizel
Endre
E
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology* / Q000209:etiology; D000328:Adult; D000871:Anthelmintics / Q000009:adverse effects*; D016022:Case-Control Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D015994:Incidence; D007978:Levamisole / Q000009:adverse effects*; D011159:Population Surveillance; D011247:Pregnancy; D013723:Teratogens
D000871:Anthelmintics; D013723:Teratogens; D007978:Levamisole