title: [Study on the pretreatment of the series of HPD macroporous adsorption resin].
abstract: OBJECTIVE
  To develop a method for the pretreatment of the series of HPD macroporous adsorption resin (MAR).
  
  
  METHODS
  The effect of 2% NaOH to pretreatment of the series of HPD MAR was studied by gas chromatography and UV spectrometery.
  
  
  RESULTS
  The eluting effect by ethanol was better after the MAR was marinated and eluted by 2% NaOH.
  
  
  CONCLUSIONS
  The pretreatment of the series of HPD MAR was: after marinated and eluted by 2% NaOH, the series of HPD MAR were eluted by ethanol at 2 BV x h(-1) at 60 degrees C for 3-4 bed volumes (BV). At then the UV absorbance of eluate was 0.2-0.5. Benzene was not detected and the other residues less than 10 mg x L(-1) in eluted-MAR by GC. And the MARs match to the standard of medicine.
authors.affiliation: School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, China.
authors.forename: Cun-Qin
authors.initials: CQ
authors.lastname: Jia
authors.forename: Yang-Chun
authors.initials: YC
authors.lastname: Li
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Tu
authors.forename: Hong-Quan
authors.initials: HQ
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D002849:Chromatography, Gas; D004340:Drug Contamination; D000431:Ethanol; D009281:Naphthalenes / Q000032:analysis; D012117:Resins, Synthetic / Q000737:chemistry; D012972:Sodium Hydroxide; D013056:Spectrophotometry, Ultraviolet; D014050:Toluene / Q000032:analysis
chemical_list: D009281:Naphthalenes; D012117:Resins, Synthetic; C031721:naphthalene; D014050:Toluene; D000431:Ethanol; D012972:Sodium Hydroxide