title: Arene cis-dihydrodiol formation: from biology to application.
abstract: The range of available arene dihydroxylating dioxygenase enzymes, their structure and mechanism, and recent examples of the application of arene cis-dihydrodiol bioproducts as chiral precursors in the synthesis of natural and unnatural products and chiral ligands are discussed.
authors.affiliation: School of Chemistry and Centre for Theory and Application of Catalysis, Queen's University of Belfast, Belfast, UKBT9 5AG.
authors.forename: Derek R
authors.initials: DR
authors.lastname: Boyd
authors.forename: Timothy D H
authors.initials: TD
authors.lastname: Bugg
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis; D049308:Dioxygenases / Q000378:metabolism*; D006841:Hydrocarbons, Aromatic / Q000378:metabolism*; D008024:Ligands; D009281:Naphthalenes / Q000378:metabolism*
chemical_list: D001688:Biological Products; D006841:Hydrocarbons, Aromatic; D008024:Ligands; D009281:Naphthalenes; C507866:trans-1,2-dihydro-1,2-naphthalenediol; D049308:Dioxygenases