title: Pooled analysis of two case-control studies on the use of cellular and cordless telephones and the risk of benign brain tumours diagnosed during 1997-2003.
abstract: The use of cellular and cordless telephones and the risk of brain tumours is of concern since the brain is a high exposure area. We present the results of a pooled analysis of two case-control studies on benign brain tumours diagnosed during 1997-2003 including answers from 1,254 (88%) cases and 2,162 (89%) controls aged 20-80 years. For acoustic neuroma, the use of analogue cellular phones gave an odds ratio (OR) of 2.9 and a 95% confidence interval (CI) of 2.0-4.3; for digital cellular phones, OR=1.5; 95% CI=1.1-2.1; and for cordless telephones, OR=1.5, 95% CI=1.04-2.0. The highest OR was found for analogue phones with a latency period of >15 years; OR=3.8, 95% CI=1.4-10. Regarding meningioma, the results were as follows: for analogue phones, OR=1.3, 95% CI=0.99-1.7; for digital phones, OR=1.1, 95% CI=0.9-1.3; and for cordless phones, OR=1.1, 95% CI=0.9-1.4. In the multivariate analysis, a significantly increased risk of acoustic neuroma was found with the use of analogue phones.
authors.affiliation: Department of Oncology, University Hospital, SE-701 85 Orebro, Sweden. lennart.hardell@orebroll.se
authors.forename: Lennart
authors.initials: L
authors.lastname: Hardell
authors.forename: Michael
authors.initials: M
authors.lastname: Carlberg
authors.forename: Kjell
authors.initials: K
authors.lastname: Hansson Mild
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000209:etiology*; D016022:Case-Control Studies; D040421:Cell Phone; D005260:Female; D006801:Humans; D008297:Male; D008579:Meningioma / Q000209:etiology*; D008875:Middle Aged; D015999:Multivariate Analysis; D009464:Neuroma, Acoustic / Q000209:etiology*; D016017:Odds Ratio; D012307:Risk Factors; D013548:Sweden; D013997:Time Factors