title: Change in mobility activity in the second year after stroke in a rehabilitation population: who is at risk for decline?
abstract: OBJECTIVE
  To investigate the development of mobility status during the second year after stroke in patients who had had inpatient rehabilitation, and to evaluate risk factors for mobility decline.
  
  
  METHODS
  Evaluation of change in Rivermead Mobility Index (RMI) score over the second year after stroke in an inception cohort of first-ever stroke patients eligible for inpatient rehabilitation. Logistic regression techniques were used to predict decline. Independent variables were measured with standardized instruments 1 year after stroke.
  
  
  METHODS
  Home or institution, after discharge from rehabilitation center.
  
  
  METHODS
  Patients (N=148) with single first-ever stroke (supratentorial), age more than 18 years.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Decline of 2 or more points on the RMI and the percentages and odds ratios (ORs) for decline.
  
  
  RESULTS
  The mean RMI score did not significantly change over time. Mobility declined in 12% of the patients. Mobility decline was found more often in patients with depression (25%) than without (7%), with right-sided weakness (17% vs 8%), with ischemic stroke (13% vs 8%), with aphasia (22% vs 11%), with cognitive dysfunction (17% vs 11%), with comorbidity interfering with locomotion (25% vs 12%), with poor social functioning (15% vs 10%), and with mobility disability (16% vs 8%). Statistical significance was found only for depression (OR=4.2; 95% confidence interval, 1.3-13.2).
  
  
  CONCLUSIONS
  Most patients maintained the level of mobility they achieved during inpatient rehabilitation over the second year after stroke. Only 12% had a decline in mobility, and depression was the only statistically significant predictor for decline.
authors.affiliation: Rehabilitation Center de Hoogstraat, Rudolph Magnus Institute of Neuroscience, Department of Rehabilitation, University Medical Center Utrecht, the Netherlands. i.v.wijk@dehoogstraat.nl
authors.forename: Iris
authors.initials: I
authors.lastname: van Wijk
authors.forename: Ale
authors.initials: A
authors.lastname: Algra
authors.forename: Ingrid G
authors.initials: IG
authors.lastname: van de Port
authors.forename: Bas
authors.initials: B
authors.lastname: Bevaart
authors.forename: Eline
authors.initials: E
authors.lastname: Lindeman
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D010351:Patient Discharge; D026741:Physical Therapy Modalities; D011336:Probability; D020127:Recovery of Function / Q000502:physiology*; D012047:Rehabilitation Centers; D012307:Risk Factors; D018709:Statistics, Nonparametric; D020521:Stroke / Q000175:diagnosis*; D000071939:Stroke Rehabilitation; D013997:Time Factors