A simple guide for predicting regioselectivity in the coupling of polyhaloheteroaromatics.
A simple guide for predicting the order and site of coupling (Suzuki, Stille, Negishi, Sonogashira, etc.) in polyhaloheteroaromatics based upon the (1)H NMR chemical shift values of the parent non-halogenated heteroaromatics has been developed.
Handy
Scott T
ST
Department of Chemistry, Middle Tennessee State University, Murfreesboro, 37132, USA. shandy@mtsu.edu
Zhang
Yanan
Y