title: Primary intraosseous carcinoma and odontogenic cyst. Three new cases and review of the literature.
abstract: BACKGROUND
  The Odontogenic Primary Intraosseous Carcinoma (PIOC) are a rare group of malignant tumours with strict clinic and anatomy pathological diagnosis criteria. The different classification suggested for these tumours and the small amount of cases described in literature makes it hard to know exactly how many of the cases published until now are real.
  
  
  METHODS
  We present three new cases of PIOC originated from a previous cystic lesion that where treated in our Hospital. Two of them in the posterior jaw region where is more frequent, and the third in the upper jaw. We explain the procedure we used in each case and the aesthetic-functional reconstruction used witches are two fibula osteomyocutaneous free flaps and a bone graft of iliac crest and further placing of implants. The classification, the clinical and radiological diagnosis, the treatment and its survival are discussed.
  
  
  RESULTS
  In all three cases we were able to see in the anatomy pathological study an epithelial, exclusively without surrounding oral mucosa affectation or tissues near the lesion as well as the lack of tumorous pathology in other parts of the body. One of the patients died because of premature massive cervical recidiva while the other two patients are currently free form illness, for ten years one of them and fifteen months the other.
  
  
  CONCLUSIONS
  The anatomy pathological study of all of the lesions of cystic characteristics at jaw level is very important because of the risk of coexisting with carcinomatous cells. The treatment of these tumours consists in practising aggressive surgery and, in some cases, radio and/or chemotherapy post intervention.
authors.affiliation: Hospital Universitari de Bellvitge. samir74es@yahoo.es
authors.forename: Samir
authors.initials: S
authors.lastname: Aboul-hosn Centenero
authors.forename: Antonio
authors.initials: A
authors.lastname: Marí-Roig
authors.forename: Pedro
authors.initials: P
authors.lastname: Piulachs-Clapera
authors.forename: Inma
authors.initials: I
authors.lastname: Juárez-Escalona
authors.forename: Antonio
authors.initials: A
authors.lastname: Monner-Diéguez
authors.forename: Arturo
authors.initials: A
authors.lastname: Díaz-Carandell
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Lluch
authors.forename: Josep
authors.initials: J
authors.lastname: Pericot-Ayats
mesh_terms: D000293:Adolescent; D002471:Cell Transformation, Neoplastic; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000473:pathology*; D051527:Odontogenic Tumor, Squamous / Q000145:classification / Q000473:pathology* / Q000601:surgery; D019647:Oral Surgical Procedures / Q000379:methods; D011230:Precancerous Conditions / Q000473:pathology* / Q000601:surgery; D013524:Surgical Flaps; D009626:Terminology as Topic