[Clinical research of qingkailing soft capsules in treating acute upper respiratory infection].
OBJECTIVE
To discuss the efficacy of Qingkailing soft capsules in treating acute fever, and the relationship between symptoms-effect and time effect.


METHODS
Qingkailing soft capsules was taken orally, 4 times a day, 1.6 g each time. Shuanghuanglian kou fu liquid was taken as control. 129 patients with acute upper respiratory tract infection were recruited.


RESULTS
There were 73.34% of patients cured by Qingkailing soft capsules and 43.59% cured by Shuanghuanglian kou fu liquid. The efficacy of the former was better than that of the latter (P < 0.05). The efficacy of Qingkailing soft capsules in treating Fengrexing was better than that in Fenghanxing (P < 0.05). The efficacy of Qingkailing soft capsules in reducing rapid pulse and adding moderate pulse was more remarkable than Shuanghuanglian kou fu liquid (P < 0.05). Taking Qingkailing soft capsules seldom induced mild gastrointestinal disturbance.


CONCLUSIONS
Qingkailing soft capsules showed good result in the treatment of acute upper respiratory tract infection with less adverse effect.
Li
Chun-sheng
CS
Xiyuan Hospital, Academy of Traditional Chinese Medicine, Beijing 100091, China.
Li
Jie
J
Wang
Xiu-zhen
XZ
Wang
Xian-chun
XC
Lin
Xian-yi
XY
Liu
Shao-neng
SN
Tang
Xu-dong
XD
Kong
Wei-ping
WP
Wang
Shu
S
Shang
Yan-zhong
YZ
Fan
Jin
J
Zheng
Shu-yi
SY
D000328:Adult; D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008419:Materia Medica / Q000302:isolation & purification / Q000627:therapeutic use*; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D012141:Respiratory Tract Infections / Q000188:drug therapy*
D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica; C504928:Qingkailing