TreeFam: a curated database of phylogenetic trees of animal gene families.
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as well as reliable ortholog and paralog assignments. Curated families are being added progressively, based on seed alignments and trees in a similar fashion to Pfam. Release 1.1 of TreeFam contains curated trees for 690 families and automatically generated trees for another 11 646 families. These represent over 128 000 genes from nine fully sequenced animal genomes and over 45 000 other animal proteins from UniProt; approximately 40-85% of proteins encoded in the fully sequenced animal genomes are included in TreeFam. TreeFam is freely available at http://www.treefam.org and http://treefam.genomics.org.cn.
Li
Heng
H
Beijing Institute of Genomics of the Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China.
Coghlan
Avril
A
Ruan
Jue
J
Coin
Lachlan James
LJ
Hériché
Jean-Karim
JK
Osmotherly
Lara
L
Li
Ruiqiang
R
Liu
Tao
T
Zhang
Zhang
Z
Bolund
Lars
L
Wong
Gane Ka-Shu
GK
Zheng
Weimou
W
Dehal
Paramvir
P
Wang
Jun
J
Durbin
Richard
R
D000818:Animals; D030541:Databases, Genetic; D019143:Evolution, Molecular; D005796:Genes; D023281:Genomics; D006801:Humans; D020407:Internet; D051379:Mice; D010802:Phylogeny; D011506:Proteins / Q000145:classification* / Q000235:genetics; D051381:Rats; D012984:Software; D014584:User-Computer Interface
D011506:Proteins