title: Part III: Surface-enhanced Raman scattering of amino acids and their homodipeptide monolayers deposited onto colloidal gold surface.
abstract: Surface-enhanced Raman scattering (SERS) spectra were measured for monolayers of various amino acids: L-methionine (Met), L-cysteine (Cys), L-glycine (Gly), L-leucine (Leu), L-phenylalanine (Phe), and L-proline (Pro) and their homodipeptides (Met-Met, Cys-Cys, Gly-Gly, Leu-Leu, Phe-Phe, and Pro-Pro) deposited onto a colloidal gold surface. Orientation of amino acids and their homodipeptides, as well as specific-competitive interactions of their functional groups with the gold surface, were predicted by detailed spectral analysis of the obtained SERS spectra. The analysis performed allowed us to propose a particular surface geometry for each amino acid and homodipeptide on the gold surface. In addition, we compared the structures of these molecules adsorbed on colloidal gold and silver surfaces.
authors.affiliation: Laser Raman Laboratory, Regional Laboratory of Physicochemical Analysis and Structural Research, Jagiellonian University, ul. Ingardena 3, 30-060 Krakow, Poland. podstawk@chemia.uj.edu.pl
authors.forename: Edyta
authors.initials: E
authors.lastname: Podstawka
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Ozaki
authors.forename: Leonard M
authors.initials: LM
authors.lastname: Proniewicz
mesh_terms: D000596:Amino Acids / Q000032:analysis* / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000032:analysis / Q000737:chemistry*; D004151:Dipeptides / Q000032:analysis / Q000737:chemistry*; D017979:Gold Colloid / Q000032:analysis / Q000737:chemistry*; D008027:Light; D010316:Particle Size; D011485:Protein Binding; D012542:Scattering, Radiation; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D000596:Amino Acids; D020099:Coated Materials, Biocompatible; D004151:Dipeptides; D017979:Gold Colloid