title: Vaccination coverage in adults undergoing splenectomy: evaluation of hospital vaccination policies.
abstract: Vaccination coverage in 595 adult patients undergoing total splenectomy in the Hospital Clinic of Barcelona during 1992-2002 was studied. The rates of cover for pneumococcal, Haemophilus influenzae type b and meningococcal vaccines were 63, 63 and 61% respectively, during 2000-2002; 32, 17 and 22% in 1997-1999; and 24, 9 and 8% in 1992-1996. Multivariate analysis showed a greater risk of no vaccination in splenectomies due to trauma, malignant neoplasms of solid organs and incidental splenectomy compared with both neoplastic and non-neoplastic haematological disease, and those patients undergoing splenectomy before 2001. Coverage (>/=1 vaccine) since 1997 in patients with haematological diseases was 83.5% (71/85), haematological neoplasias 69.2% (18/26), solid organ neoplasms 38.3% (36/94), incidental splenectomy 35.6% (16/45), and traumas 28.4% (21/74). Mandatory hospital admission of patients undergoing splenectomy offers a good opportunity for vaccination of these patients. Specific vaccination policies should be developed to take advantage of this circumstance.
authors.affiliation: Preventive Medicine Service, Adult Vaccination Centre, Hospital Clínic -- IDIBAPS, Barcelona, Spain. laiabruni@comb.es
authors.forename: L
authors.initials: L
authors.lastname: Bruni
authors.forename: J M
authors.initials: JM
authors.lastname: Bayas
authors.forename: A
authors.initials: A
authors.lastname: Vilella
authors.forename: A
authors.initials: A
authors.lastname: Conesa
mesh_terms: D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D005260:Female; D018073:Haemophilus Vaccines / Q000008:administration & dosage; D006760:Hospitalization; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D022401:Meningococcal Vaccines / Q000008:administration & dosage; D008875:Middle Aged; D022242:Pneumococcal Vaccines / Q000008:administration & dosage; D013030:Spain; D013156:Splenectomy; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D018073:Haemophilus Vaccines; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines