title: Resistance pattern of antibiotics against clinical isolates of Staphylococcus aureus.
abstract: The present research was conducted to study the susceptibility and resistance pattern of Staphylococcus aureus isolates against various brands of commonly used antibiotics. A total of 50 bacterial isolates were obtained from various clinical specimens submitted to the clinical laboratory of Pakistan Institute of Medical Sciences Islamabad (PIMS). Out of 50 isolates 30 (60%) were identified as coagulase positive Staphylococcus aureus. These isolates were tested for susceptibility pattern 19 (63%), these isolates were resistant to penicillin, 17 (57%) to ampicillin, 19 (63%) to cloxacillin, 20 (67%) to streptomycin, 11 (37%) to clindamycin, 16 (53%) to lincomycin and 19 (63%) to neomycin. These isolates had MIC range of penicillin and lincomycin (<0.5 to > 512 microg/mL), ampicillin, cloxacillin and clindamycin (0.5 to 256 microg/mL), streptomycin (4 to >512 microg/mL) and neomycin (2 to 256 microg/mL). Clindamycin was found to be the most effective among these antibiotics tested in the study against these clinical isolates.
authors.affiliation: Department of Biological Sciences, Quaid-i-Azam University, Islamabad.
authors.forename: Safama Abdul
authors.initials: SA
authors.lastname: Sattar
authors.forename: Kalsoom
authors.initials: K
authors.lastname: Farzana
authors.forename: Abdul
authors.initials: A
authors.lastname: Hameed
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents