Progression of peripheral anterior synechiae after laser iridotomy.
OBJECTIVE
To determine the incidence and to characterize the risk factors of peripheral anterior synechiae (PAS) progression after laser iridotomy (LI).


METHODS
Retrospective observational cohort study.


METHODS
The extents of pre- and postlaser PAS and ocular and systemic data were obtained from the charts of 54 primary angle-closure glaucoma patients (59 eyes), all of whom had undergone LI.


RESULTS
PAS progressed in 19 of the 59 eyes (32.2%), during a mean follow-up period of 34.4 months (range, 6-95 months). Multivariate analysis showed that the presence of plateau iris (P = .024), and a high intraocular pressure 1 hour before LI (P = .042) were risk factors of PAS progression.


CONCLUSIONS
Approximately one of three of the eyes showed PAS progression during a 3-year follow-up period after LI. The probability of progression was found to be higher in the eyes that exhibited plateau iris and in eyes that proved to be relatively unresponsive to medication before LI.
Choi
Jun Sung
JS
Department of Ophthalmology, Korea University College of Medicine, Guro Hospital, 97 Gurodong-gil, Guro-gu, Seoul 152-703, South Korea.
Kim
Yong Yeon
YY
D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D032801:Iridectomy; D007498:Iris / Q000601:surgery; D007499:Iris Diseases / Q000175:diagnosis*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D000267:Tissue Adhesions; D014129:Trabecular Meshwork / Q000473:pathology*