[The significance of microvessel density and CD34 expression in nasal polyps].
OBJECTIVE
To study the clinicopathologic significance of microvessel density (MVD) and the expression of CD34 in human nasal polyps.


METHODS
Using Elivision Plus immunohistochemistry method. Thirty cases of normal inferior turbinate, 60 cases of nasal polyps were stain with CD34.


RESULTS
MVD of CD34 marker showed higher in the group of nasal polyps than in the group of normal inferior turbinate (P <0.01). MVD in nasal polyps type II phase 3 and type III was higher than that in the nasal polyps type II phase (P < 0.01).


CONCLUSIONS
MVD is closely related with the formation edema and development of nasal polyps. Angiogenesis may play an important role in the development of nasal polyps.
Yao
Li
L
Department of Otolaryngology, Third Hospital, Peking University, Beijing, 100083, China.
Li
Xuepei
X
Lu
Xing
X
Yin
Weihua
W
D000293:Adolescent; D000328:Adult; D018952:Antigens, CD34 / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D055806:Microvessels; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism* / Q000473:pathology; D009389:Neovascularization, Pathologic; D055815:Young Adult
D018952:Antigens, CD34