title: Prevalence and evolution of methicillin-resistant Staphylococcus aureus in Spanish hospitals between 1996 and 2002.
abstract: Pulsed-field gel electrophoretic analysis of 2,144 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from patients in Spanish hospitals over a 7-year period revealed 17 predominant profiles. Typing showed the replacement of Iberian clone E1 (ST247-MRSA-I) by two prevalent clones, E7 and E8, that are closely related to each other and have the same genetic background as ST125-MRSA-IV.
authors.affiliation: Nosocomial Infectious Diseases Laboratory, Servicio de Bacteriología, Instituto de Salud Carlos III, Centro Nacional de Microbiología, Madrid, Spain. avindel@isciii.es
authors.forename: A
authors.initials: A
authors.lastname: Vindel
authors.forename: P
authors.initials: P
authors.lastname: Trincado
authors.forename: E
authors.initials: E
authors.lastname: Gómez
authors.forename: R
authors.initials: R
authors.lastname: Cabrera
authors.forename: T
authors.initials: T
authors.lastname: Boquete
authors.forename: C
authors.initials: C
authors.lastname: Solá
authors.forename: S
authors.initials: S
authors.lastname: Valdezate
authors.forename: J A
authors.initials: JA
authors.lastname: Saez-Nieto
mesh_terms: D005075:Biological Evolution; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D019143:Evolution, Molecular; D005798:Genes, Bacterial / Q000235:genetics; D006761:Hospitals; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance / Q000235:genetics*; D015995:Prevalence; D013030:Spain; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000145:classification* / Q000187:drug effects / Q000235:genetics
chemical_list: D008712:Methicillin