title: [Severe infections: source control and antimicrobial therapy].
abstract: Source control and antimicrobial therapy together are the keys of successful treatment of sever infections. Source control may be surgical, radiological nor medical. Whatever the cause, drainage is the main important point. Antimicrobial therapy has to be introduced early in the course of infection, must be adequate, essentially with a broad spectrum and prescribed at the right dosage. Combination of antimicrobial therapy is more justified by broadening spectrum than for obtaining synergy.
authors.affiliation: Unité de réanimation polyvalente, département d'anesthésie-réanimation, centre hospitalier universitaire Nord, place Victor-Pauchet, Amiens, France. dupont.herve@chu-amiens.fr
authors.forename: H
authors.initials: H
authors.lastname: Dupont
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000517:prevention & control*; D003428:Cross Infection / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D017053:Infection Control / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents