title: Occurrence of polychlorinated biphenyls and polybrominated diphenyl ethers in belgian human adipose tissue samples.
abstract: Levels of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were measured in 53 human adipose tissue samples. The samples consisted of adipose tissue from 31 men and 22 women having a mean age of 53 years. No information about diet or occupational exposure was collected. Cleanup was performed using a glass column containing acidified silica, deactivated alumina, and anhydrous sodium sulphate. Subsequently, samples were analyzed by high-resolution gas chromatography/tandem mass spectrometry. PBDE concentrations (sum of BDEs 28, 47, 99, 100, 154, 153, and 183) ranged between 1.23 and 57.2 ng g(-1) lipid weight and were comparable with levels in samples from other European countries. The sum of seven International Council for the Exploration of the Sea (ICES) indicator PCB congeners (PCBs 28, 52, 101, 118, 138, 153, and 180) ranged from 126 to 2090 ng g(-1) lipid weight. No age dependency was found for PBDEs (Pearson correlation -0.023, p = 0.873), whereas PCBs showed higher correlation coefficients with age (Pearson correlation 0.613, p < 0.0005). There was no relationship between PBDE and PCB levels (Pearson correlation -0.010, p = 0.943).
authors.affiliation: Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, Ghent 9000, Belgium. Caroline.Naert@UGent.be
authors.forename: C
authors.initials: C
authors.lastname: Naert
authors.forename: M
authors.initials: M
authors.lastname: Piette
authors.forename: N
authors.initials: N
authors.lastname: Bruneel
authors.forename: C
authors.initials: C
authors.lastname: Van Peteghem
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry* / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001530:Belgium; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis* / Q000378:metabolism; D005260:Female; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000032:analysis* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010647:Phenyl Ethers / Q000032:analysis* / Q000378:metabolism; D011075:Polybrominated Biphenyls / Q000032:analysis* / Q000378:metabolism
chemical_list: D004785:Environmental Pollutants; D006842:Hydrocarbons, Brominated; D010647:Phenyl Ethers; D011075:Polybrominated Biphenyls