title: WormBase: better software, richer content.
abstract: WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.
authors.affiliation: Division of Biology, 156-29 California Institute of Technology, Pasadena, CA, 91125, USA. emsch@its.caltech.edu
authors.forename: Erich M
authors.initials: EM
authors.lastname: Schwarz
authors.forename: Igor
authors.initials: I
authors.lastname: Antoshechkin
authors.forename: Carol
authors.initials: C
authors.lastname: Bastiani
authors.forename: Tamberlyn
authors.initials: T
authors.lastname: Bieri
authors.forename: Darin
authors.initials: D
authors.lastname: Blasiar
authors.forename: Payan
authors.initials: P
authors.lastname: Canaran
authors.forename: Juancarlos
authors.initials: J
authors.lastname: Chan
authors.forename: Nansheng
authors.initials: N
authors.lastname: Chen
authors.forename: Wen J
authors.initials: WJ
authors.lastname: Chen
authors.forename: Paul
authors.initials: P
authors.lastname: Davis
authors.forename: Tristan J
authors.initials: TJ
authors.lastname: Fiedler
authors.forename: Lisa
authors.initials: L
authors.lastname: Girard
authors.forename: Todd W
authors.initials: TW
authors.lastname: Harris
authors.forename: Eimear E
authors.initials: EE
authors.lastname: Kenny
authors.forename: Ranjana
authors.initials: R
authors.lastname: Kishore
authors.forename: Dan
authors.initials: D
authors.lastname: Lawson
authors.forename: Raymond
authors.initials: R
authors.lastname: Lee
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Müller
authors.forename: Cecilia
authors.initials: C
authors.lastname: Nakamura
authors.forename: Phil
authors.initials: P
authors.lastname: Ozersky
authors.forename: Andrei
authors.initials: A
authors.lastname: Petcherski
authors.forename: Anthony
authors.initials: A
authors.lastname: Rogers
authors.forename: Will
authors.initials: W
authors.lastname: Spooner
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Tuli
authors.forename: Kimberly
authors.initials: K
authors.lastname: Van Auken
authors.forename: Daniel
authors.initials: D
authors.lastname: Wang
authors.forename: Richard
authors.initials: R
authors.lastname: Durbin
authors.forename: John
authors.initials: J
authors.lastname: Spieth
authors.forename: Lincoln D
authors.initials: LD
authors.lastname: Stein
authors.forename: Paul W
authors.initials: PW
authors.lastname: Sternberg
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry* / Q000235:genetics*; D018076:DNA, Complementary / Q000737:chemistry; D030541:Databases, Genetic; D020224:Expressed Sequence Tags / Q000737:chemistry; D049751:Genome, Helminth; D023281:Genomics; D020407:Internet; D020641:Polymorphism, Single Nucleotide; D034622:RNA Interference; D012984:Software; D014584:User-Computer Interface
chemical_list: D029742:Caenorhabditis elegans Proteins; D018076:DNA, Complementary