title: Membranoproliferative glomerulonephritis complicating diabetic nephropathy.
abstract: BACKGROUND
  Renal diseases other than diabetic nephropathy can be found in diabetic patients who have undergone renal biopsy. Various forms of primary and secondary glomerular diseases were reported, but membranoproliferative glomerulonephritis was rare.
  
  
  METHODS
  Analyzing data at our Department for the past three years, we noted 18 patients with primary membranoproliferative glomerulonephritis and 4 associated with diabetic nephropathy.
  
  
  RESULTS
  Nodular glomerulosclerosis with diffuse membranoproliferative glomerulonephritis was registered in two patients and a diffuse form of diabetic nephropathy with a combination of segmental and diffuse changes characteristic of membranoproliferative glomerulonephritis in the other two patients.
  
  
  CONCLUSIONS
  Analyzing what can be common for these two diseases we can conclude that they are at least three disorders: 1. hyperperfusion injury, hallmark for the diabetic nephropathy, but also with the highest incidence in membranoproliferative glomerulonephritis than in the other glomerulonephritides; 2. mesangial matrix expansion, and; 3. thickening of all extracellular membranes.
authors.affiliation: Department of Nephrology, Clinical Center Skopje, R. Macedonia. makrofpo@mt.net.mk
authors.forename: L
authors.initials: L
authors.lastname: Grcevska
authors.forename: G
authors.initials: G
authors.lastname: Petrusevska
authors.forename: S
authors.initials: S
authors.lastname: Dzikova
authors.forename: S
authors.initials: S
authors.lastname: Kostadinova
authors.forename: M
authors.initials: M
authors.lastname: Polenaković
mesh_terms: D000328:Adult; D003928:Diabetic Nephropathies / Q000150:complications* / Q000473:pathology; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008875:Middle Aged