title: [Health-related quality of life in Japanese patients with ischemic heart disease: a multicenter cooperative investigation assessed using SF-36].
abstract: OBJECTIVE
  To investigate the quality of life (QOL) of Japanese patients with ischemic heart disease.
  
  
  METHODS
  The QOL data of 753 patients with chronic and stable ischemic heart disease was assessed using SF-36 Japanese version 1.2 and compared with Japanese national norms. Physical (PCS) and Mental Component Summary (MCS) scores were calculated to examine the correlation with patient background. Patients were also asked about subjective symptoms during the QOL investigation.
  
  
  RESULTS
  Mean age was 63.6 +/- 7.5 years old and the male/female ratio was 85.7/14.3. About one third (30.7%) of the patients were symptomatic and about half (52.6%) had a history of myocardial infarction. Compared to Japanese national norms, physical functioning, role-physical, social functioning, general health and role-emotional were lower, and body pain, vitality and mental health were higher. PCS was significantly lower and MCS was significantly higher in aged patients than in younger patients (p < 0.0001, p < 0.0001). PCS and MCS were significantly lower in the symptom (+) group than in the symptom (-) group (p = 0.0009, p < 0.0001). PCS decreased as the number of anti-angina medications for the patients increased (p = 0.0002). PCS was significantly lower and MCS was significantly higher in the beta blocker (+) group than in the beta blocker (-) group (p < 0.0001, p < 0.03). Multivariate logistic regression analysis showed that age ( > or = 63 years old), symptom (+), duration of disease (> or = 3 years) and beta blocker (+) influenced the QOL.
  
  
  CONCLUSIONS
  The QOL level of patients with ischemic heart disease was found to depend on the clinical condition and treatment, so the optimal treatment for ischemic heart disease must be established to improve QOL.
authors.affiliation: Department of General Internal Medicine, Toranomon Hospital, Kanagawa. nishiyama@toranomon.gr.jp
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Nishiyama
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Momomura
authors.forename: Sugao
authors.initials: S
authors.lastname: Ishiwata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Daida
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hara
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Nishimura
authors.forename: Masato
authors.initials: M
authors.lastname: Nakamura
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Shirai
authors.forename: Nishi
authors.initials: N
authors.lastname: Yutaro
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Yamazaki
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D005260:Female; D006306:Health Surveys; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017202:Myocardial Ischemia / Q000523:psychology / Q000628:therapy; D011788:Quality of Life; D011795:Surveys and Questionnaires
chemical_list: D000319:Adrenergic beta-Antagonists