[Apoptosis of cardiomyocytes, cytokines and remodeling of myocardium against the development of chronic heart failure].
A literature review considers apoptosis-related immunological aspects of chronic heart failure (CHF). Scientific data on the induction of cardiomiocyte apoptosis, NO and immune factors--cytokines in the development of CHF and remodeling of myocardium were analyzed. Modern approaches of therapy for patients with CHF were discussed in the article. They include combined correction of functioning mechanisms of neurohumoral systems and elimination of adverse effects of apoptosis--associated cytokine "aggression".
Dynnik
O B
OB
Gavrilenko
T I
TI
Zalesskiĭ
V N
VN
D017209:Apoptosis / Q000276:immunology*; D002908:Chronic Disease; D016207:Cytokines / Q000097:blood / Q000276:immunology*; D006333:Heart Failure / Q000276:immunology / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D009206:Myocardium / Q000276:immunology; D032383:Myocytes, Cardiac / Q000276:immunology*; D012196:Review Literature as Topic; D020257:Ventricular Remodeling
D016207:Cytokines