Antioxidative and antiradical properties of plant phenolics.
The plant phenolic compounds such as flavonoids, tannins and phenolic acids appeared to be strong antiradical and antioxidant compounds. The number of hydroxy groups and the presence of a 2,3-double bond and orthodiphenolic structure enhance antiradical and antioxidative activity of flavonoids. The glycosylation, blocking the 3-OH group in C-ring, lack of a hydroxy group or the presence of only a methoxy group in B-ring have a decreasing effect on antiradical or antioxidative activity of these compounds. Tannins show strong antioxidative properties. Some tannins in red wine or gallate esters were proved to have antioxidative effect in vivo. The number of hydroxy groups connected with the aromatic ring, in ortho or para position relative to each other, enhance antioxidative and antiradical activity of phenolic acids. The substitution of a methoxy group in ortho position to the OH in monophenols seems to favour the antioxidative activity of the former.
Sroka
Zbigniew
Z
Department of Pharmacognosy, Wrocław University of Medicine, Poland. zbsroka@bf.uni.wroc.pl
D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000494:pharmacology*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D010944:Plants / Q000737:chemistry*
D000975:Antioxidants; D047309:Flavones; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols