title: Familial testicular tumour in two brothers: a case report.
abstract: Testicular tumors account for 1% of all cancers in men and it occurs in 1 in 500 men. Incidence of familial testicular tumours is rare. Total number of cases till the year 1992 in identical twins is 21, in brothers 82 and father-son both affected in 31 pairs. We report a case of two brothers presenting simultaneously with testicular tumours. Both were subjected to retrograde orchidectomy. Histopathologic examination of one revealed embryonal cell carcinoma and other mature teratoma of the testis. Patient with embryonal carcinoma was given adjuvant chemotherapy based on Bleomycin, Etoposide and cisplatinum (BEP) and one with mature teratoma was put on a follow up.
authors.affiliation: Department of Radiotherapy & Oncology, Regional Cancer Centre, IGMC, Shimla, India. mkgupta62@yahoo.co.in
authors.forename: M K
authors.initials: MK
authors.lastname: Gupta
authors.forename: R K
authors.initials: RK
authors.lastname: Seam
authors.forename: D S
authors.initials: DS
authors.lastname: Gurung
authors.forename: S
authors.initials: S
authors.lastname: Kanika
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D018237:Germinoma / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009919:Orchiectomy; D010375:Pedigree; D018570:Risk Assessment; D035781:Siblings; D013736:Testicular Neoplasms / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome