Syntheses of hydroxylated cyclic beta-amino acid derivatives.
This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated beta-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated beta-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.
Palkó
Márta
M
Institute of Pharmaceutical Chemistry, University of Szeged, H-6701 Szeged, PO Box 121, Hungary.
Kiss
Loránd
L
Fülöp
Ferenc
F
D000598:Amino Acids, Cyclic / Q000138:chemical synthesis*; D000890:Anti-Infective Agents / Q000138:chemical synthesis; D006900:Hydroxylation; D011692:Puromycin Aminonucleoside / Q000138:chemical synthesis; D013237:Stereoisomerism; D047090:beta-Lactams / Q000138:chemical synthesis
D000598:Amino Acids, Cyclic; D000890:Anti-Infective Agents; D047090:beta-Lactams; D011692:Puromycin Aminonucleoside