title: Significance of release technology in tissue engineering.
abstract: Regenerative medical therapy has been expected to compensate for the therapeutic disadvantages of reconstructive surgery and organ transplantation, as well as offering a new therapeutic strategy. The objective of regenerative medical therapy is to induce the repair of defective tissues based on the natural healing potential of patients. For successful tissue regeneration, it is indispensable to provide cells with a local environment of artificial extracellular matrix where they can proliferate and differentiate efficiently. Tissue engineering is the key to this regeneration environment; release technology often enhances the in vivo stability of growth factors and related genes and prolongs the maintenance of biological functions for tissue regeneration.
authors.affiliation: Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. yasuhiko@frontier.kyoto-u.ac.jp
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tabata
mesh_terms: D000818:Animals; D003692:Delayed-Action Preparations; D006133:Growth Substances; D006801:Humans; D020100:Hydrogels; D018919:Neovascularization, Physiologic; D010012:Osteogenesis; D012038:Regeneration; D023822:Tissue Engineering
chemical_list: D003692:Delayed-Action Preparations; D006133:Growth Substances; D020100:Hydrogels