[Comparison of liver abscess between diabetic patients and non-diabetic patients].
OBJECTIVE
Klebsiella pneumoniae is emerging as the leading cause for liver abscess although the most common pathogen was Escherichia coli in the past. Patients with diabetes mellitus are more likely to have a pyogenic liver abscess with gas forming infection; a gas forming pyogenic liver abscess carries a higher morbidity and mortality than the non-gas forming group. This study was conducted to clarify the clinical presentation and prognostic factors for pyogenic liver abscess in diabetic patients compared with non-diabetic patients.


METHODS
Medical records of 140 cases of patients treated for pyogenic liver abscess from January 1995 through January 2004 were reviewed retrospectively in detail.


RESULTS
Among 140 cases of pyogenic liver abscess, underlying diabetes was present in 26.4% (37/140). The clinical presentation between the two groups was not significantly different. The most common organism for the pyogenic abscess was K. pneumoniae in both groups. A gas forming liver abscess was discovered in only the diabetic liver abscess group, 6 of 37 patients (16%).


CONCLUSIONS
K. pneumoniae was the most common organism cultured in both diabetic and non-diabetic liver abscess. Gas forming liver abscess was more common in diabetic patients than non-diabetic patients. Diabetic patients had more complications than non-diabetic patients.
Lee
Chang Jae
CJ
Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea.
Jung
Dong Sik
DS
Jung
Suk Hee
SH
Baik
Jung Hoan
JH
Lee
Jung Hyun
JH
Cho
Young Rak
YR
Go
Byoung Soung
BS
Lee
Sung Wook
SW
Han
Sang Young
SY
Lee
Dong Hyun
DH
D000328:Adult; D000368:Aged; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications; D007711:Klebsiella pneumoniae; D046290:Liver Abscess, Pyogenic / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis