title: Smaller volume of anterior cingulate cortex in abuse-related posttraumatic stress disorder.
abstract: OBJECTIVE
  The anterior cingulate cortex (ACC) plays an important role in emotion, and studies in animals have shown changes in ACC structure with early life stress. The purpose of this study was to measure volume of the ACC in PTSD.
  
  
  METHODS
  Magnetic resonance imaging (MRI) was used to measure ACC volume in 8 subjects with abuse-related PTSD and 13 healthy subjects without PTSD. ACC volume included Brodmann's area [BA] 24 and 32.
  
  
  RESULTS
  Right ACC volume in PTSD patients was significantly smaller than in non-PTSD subjects.
  
  
  CONCLUSIONS
  These results are consistent with smaller ACC volume in PTSD.
authors.affiliation: Division of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-higashi, Kodaira-shi, Tokyo 187-8553, Japan. norikita@fd6.so-net.ne.jp
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kitayama
authors.forename: Sinead
authors.initials: S
authors.lastname: Quinn
authors.forename: J Douglas
authors.initials: JD
authors.lastname: Bremner
mesh_terms: D000328:Adult; D001284:Atrophy; D002648:Child; D002649:Child Abuse / Q000175:diagnosis* / Q000523:psychology; D004292:Dominance, Cerebral / Q000502:physiology; D004644:Emotions / Q000502:physiology; D005260:Female; D006179:Gyrus Cinguli / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology