[Modification of histogenetic processes in rat nervous tissue after dexamethasone administration during prenatal development].
In experiments performed on rats, using the methods of confocal microscopy and immunohistochemistry, it was detected that administration of a single dose of synthetic corticosteroid dexamethasone during the period of increased sensitivity of developing nervous system (embryonic day 13) resulted in modification of histogenetic processes in the brain, resulting in the changes of its structural and functional characteristics during postnatal period of ontogenesis.
Korzhevskiĭ
D E
DE
Gilerovich
E G
EG
Khozhaĭ
L I
LI
Grigor'ev
I P
IP
Otellin
V A
VA
D000818:Animals; D001921:Brain / Q000166:cytology / Q000187:drug effects* / Q000196:embryology*; D003907:Dexamethasone / Q000008:administration & dosage / Q000633:toxicity*; D005260:Female; D007150:Immunohistochemistry; D018613:Microscopy, Confocal; D051381:Rats; D017208:Rats, Wistar
D003907:Dexamethasone