Plaque density on CT, a potential marker of ischemic stroke.
The authors sought to determine in a retrospective analysis whether carotid plaque soft TD on CT is associated with recent ischemic neurologic events. Among 141 patients (99 asymptomatic), 106 plaques with more than 50% stenosis were selected for density measurements. They found an odds ratio for neurologic events associated with a 10-point decrease in density of 1.54 (p = 0.002), showing an association between plaque density and neurologic events.
Serfaty
J M
JM
Department of Radiology, University Hospital Center, Lyon, France. jean-michel.serfaty@bch.aphp.fr
Nonent
M
M
Nighoghossian
N
N
Rouhart
F
F
Derex
L
L
Rotaru
C
C
Chirossel
P
P
Thabut
G
G
Guias
B
B
Heautot
J-F
JF
Gouny
P
P
de la Vega
A
A
Pachai
C
C
Ecochard
R
R
Villard
J
J
Douek
P C
PC
D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D012189:Retrospective Studies; D020521:Stroke / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed / Q000592:standards*
D015415:Biomarkers; D003287:Contrast Media