title: Recent findings with computerized methods for scalp hair growth measurements.
abstract: Sensitive tools have been developed in order to monitor hair loss and treatment responses. Recently the Tricho-Scan was presented (by RH) as such a method which combines epiluminescence microscopy (ELM) with automatic digital image analysis. Herewith new TrichoScan data obtained from 10 women and 21 men with androgenetic hair loss after 6 mo of treatment with 5%-minoxidil are presented. Even in this small cohort of patients, we noticed a significant increase of hair density, cumulative hair thickness and terminal hair counts. Alternative methods were developed during a human alopecia investigation and research technology (HAIR Technology) programme at Skinterface. This involves contrast-enhancement, image acquisition, and processing by qualified technicians followed by computer-assisted image analysis. The specific identification of exogen hair, further adds to this very refined non-invasive investigative method for hair follicle function investigation. Regional variations of hair growth dynamics do exist in the human scalp such as in female patients complaining of hair loss, scalp hair density and growth on top of the head differs significantly from the occipital site. Finally, from transversal studies and from detailed monitoring of subsequent hair cycles during longitudinal studies, data were obtained that support the fact that shortening of hair cycle, slowing down of growth rates and thinning of hair shafts are heralding hair miniaturisation. In the workshop the TrichoScan, the method of Canfield and Skinterface have been shown.
authors.affiliation: Dermaticum, Freiburg, Germany. Rolf.Hoffmann@dermaticum.de
authors.forename: Rolf
authors.initials: R
authors.lastname: Hoffmann
authors.forename: Dominique
authors.initials: D
authors.lastname: Van Neste
mesh_terms: D000328:Adult; D000505:Alopecia / Q000188:drug therapy; D003205:Computing Methodologies; D046169:Dermoscopy / Q000379:methods*; D005260:Female; D006197:Hair / Q000254:growth & development*; D018859:Hair Follicle / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008914:Minoxidil / Q000627:therapeutic use
chemical_list: D008914:Minoxidil