title: Promoting children's health through understanding of genetics and genomics.
abstract: OBJECTIVE
  To describe the effects of genetics and genomics on children's health care.
  
  
  METHODS
  The breakthroughs in the Human Genome Project have great potential for disease prediction, treatment, and prevention in the health care of children with chronic health conditions. Most childhood conditions based on a single gene are influenced by a complex interaction of genetic and environmental factors.
  
  
  METHODS
  A review of the literature was conducted to determine the most common childhood diseases linked to genetic causes.
  
  
  RESULTS
  Two examples were selected to depict how a health professional would use genetic knowledge to provide holistic health promotion and disease prevention.
  
  
  CONCLUSIONS
  Knowledge of the interaction of the genetic profile coupled with a person's lifestyle, work environment, and family context provide a more holistic picture of a person's health profile. The clinical implications are that this knowledge will provide opportunities for health professionals to advise families on individualized treatment options or to tailor health promotion to future disease states based on genes and their interaction with the environment.
authors.affiliation: University of Oklahoma Health Sciences Center, College of Nursing, Oklahoma City, OK 73117, USA. Carole-Kenner@ouhsc.edu
authors.forename: Carole
authors.initials: C
authors.lastname: Kenner
authors.forename: Agatha M
authors.initials: AM
authors.lastname: Gallo
authors.forename: Kellie D
authors.initials: KD
authors.lastname: Bryant
mesh_terms: D000755:Anemia, Sickle Cell / Q000235:genetics / Q000517:prevention & control; D030342:Genetic Diseases, Inborn / Q000235:genetics / Q000517:prevention & control*; D005820:Genetic Testing; D006293:Health Promotion; D016045:Human Genome Project; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening; D052245:Usher Syndromes / Q000235:genetics / Q000517:prevention & control