title: Polyelectrolyte multilayer film coating and stability at the surfaces of oral prosthesis base polymers: an in vitro and in vivo study.
abstract: A new type of coating involving a layer-by-layer technique has been recently reported. This coating is composed of a polyelectrolyte multilayer film that confers specific properties on surfaces to which it is applied. Here, we studied the applicability of such a technique to the coating of oral prostheses, by first testing the construction of polyelectrolyte multilayer films on several polymers used in oral prosthesis bases, and, subsequently, by studying the stability of these coatings in vitro, in human saliva, and in vivo in a rat model. We demonstrated that the multilayered films are able to coat the surfaces of all tested polymers completely, thus increasing their wettability. We also showed that saliva does not degrade the film after 7 days in vitro and after 4 days in vivo. Taken together, our results establish that the layer-by-layer technique is suitable for the coating of oral devices.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, Unité 595, 11, rue Humann, 67085 Strasbourg Cedex, France.
authors.forename: O
authors.initials: O
authors.lastname: Etienne
authors.forename: C
authors.initials: C
authors.lastname: Picart
authors.forename: C
authors.initials: C
authors.lastname: Taddei
authors.forename: P
authors.initials: P
authors.lastname: Keller
authors.forename: E
authors.initials: E
authors.lastname: Hubsch
authors.forename: P
authors.initials: P
authors.lastname: Schaaf
authors.forename: J C
authors.initials: JC
authors.lastname: Voegel
authors.forename: Y
authors.initials: Y
authors.lastname: Haikel
authors.forename: J A
authors.initials: JA
authors.lastname: Ogier
authors.forename: C
authors.initials: C
authors.lastname: Egles
mesh_terms: D000179:Acrylates / Q000737:chemistry; D000327:Adsorption; D000818:Animals; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003764:Dental Materials / Q000737:chemistry*; D017266:Dental Prosthesis; D003819:Denture Bases; D004563:Electrochemistry; D006801:Humans; D008297:Male; D008422:Materials Testing; D023421:Models, Animal; D011073:Polyamines / Q000737:chemistry; D011094:Polyethyleneimine / Q000737:chemistry; D011099:Polyglutamic Acid / Q000737:chemistry; D011107:Polylysine / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D019904:Polymethyl Methacrylate / Q000737:chemistry; D011145:Polyvinyls / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012463:Saliva / Q000737:chemistry; D012833:Siloxanes / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry; D013499:Surface Properties; D017155:Wettability
chemical_list: D000179:Acrylates; D020099:Coated Materials, Biocompatible; D003764:Dental Materials; D011073:Polyamines; D011108:Polymers; D011145:Polyvinyls; D012833:Siloxanes; D013451:Sulfonic Acids; C034183:vinyl polysiloxane; D011107:Polylysine; D011099:Polyglutamic Acid; C063994:polyallylamine; D011094:Polyethyleneimine; D019904:Polymethyl Methacrylate; C077114:styrenesulfonic acid polymer