Role of stress and sympathetic innervation in the development of polycystic ovary syndrome.
This article presents a review of the role of the sympathetic activity in ovarian pathologies affecting reproductive function. We provide a succinct outline of the findings of our group in this area. The participation of stress as an etiological factor for ovarian pathologies throughout animal models and data in patients with polycystic ovary syndrome give strong support for participation of sympathetic nerves in the ovary function both in normal and pathological status.
Greiner
Monika
M
Laboratory of Neurobiochemistry, Department Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Chile.
Paredes
Alfonso
A
Araya
Verónica
V
Lara
Hernán E
HE
D000818:Animals; D005260:Female; D000882:Haplorhini; D006801:Humans; D006080:Ovarian Follicle / Q000294:innervation / Q000503:physiopathology; D010053:Ovary / Q000294:innervation* / Q000503:physiopathology; D011085:Polycystic Ovary Syndrome / Q000209:etiology / Q000503:physiopathology*; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000502:physiology*; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology; D017779:Sympathetic Fibers, Postganglionic / Q000503:physiopathology; D013564:Sympathetic Nervous System / Q000166:cytology / Q000503:physiopathology*
D011943:Receptors, Adrenergic, beta