Determining chemical exchange rates of the uracil labile protons by NMR diffusion experiments.
The exchange rates of the amido-protons of uracil with water were determined by NMR diffusion experiments and the results showed a factor 2 difference in lability between them, which was confirmed by more classical 2D-NMR exchange experiments.
Thureau
Pierre
P
Jeune Equipe 2421 TRACES, Université de Provence et Paul Cézanne, Centre de St Jérome, 13397 Marseille cedex 20, France.
Ancian
Bernard
B
Viel
Stéphane
S
Thévand
André
A
D004058:Diffusion; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D015394:Molecular Structure; D011522:Protons; D012015:Reference Standards; D012680:Sensitivity and Specificity; D014498:Uracil / Q000737:chemistry*
D011522:Protons; D014498:Uracil