Antifertility activity of Piper longum Linn. in female rats.
The crude extract, its different fractions and the major pure compound from the active fraction of the powdered fruits of Piper longum were studied for the antifertility effect in female rats. The crude extract and its hexane fraction exhibited 100 and 86% efficacy respectively (days 1-7 post-coitum (p.c.) schedule). On the other hand, 1-butanol soluble, 1-butanol insoluble and chloroform fractions were inactive.
Lakshmi
V
V
Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow-226 001, India. vijailakshmi@rediff.com
Kumar
R
R
Agarwal
S K
SK
Dhar
J D
JD
D000019:Abortifacient Agents; D000818:Animals; D005260:Female; D031701:Piper; D010946:Plants, Medicinal; D051381:Rats; D017207:Rats, Sprague-Dawley
D000019:Abortifacient Agents