Synthesis and herbicidal activity of novel 3-aminocarbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring.
A series of 3-aminocarbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring were designed and synthesized. The structures of all of the title compounds were characterized by 1H NMR, 13C NMR, IR, and HRMS. Their agricultural bioactivities were evaluated, and some of these compounds exhibited good herbicidal activities against Echinochloa crusgalli, Sorghum vulgare, Digitaria sanguinalis, Eclipta prostrasta, Cucumis sativus, and Brassica campestris, which were associated mainly with their steric properties and lipophilicities based on the structure-activity relationship discussion.
Li
Gangyue
G
State Key Laboratory of Fine Chemicals, Dalian University of Technology, P.O. Box 89, Zhongshan Road 158, Dalian 116012, Liaoning Province, People's Republic of China.
Qian
Xuhong
X
Cui
Jingnan
J
Huang
Qingchun
Q
Zhang
Rong
R
Guan
Huai
H
D006540:Herbicides / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011725:Pyridines / Q000737:chemistry*; D013329:Structure-Activity Relationship
D006540:Herbicides; D010080:Oxazoles; D011725:Pyridines