[Stereomorphometric study of target organs in rats with hereditary stress-induced arterial hypertension at different periods of postnatal ontogenesis under changed conditions of nursing].
In rats with inherited stress-induced arterial hypertension (ISIAH strain), myocardium, adrenal gland, and renal glomerular apparatus were studied at different periods of postnatal ontogenesis (3 weeks and 6 months) to assess the influence of the changed conditions of nursing on the development of a hypertensive status and structural-functional characteristics of target organs. It was demonstrated that nursing of rats by foster normotensive Wistar females exerted a modulating influence upon the realization of stress-determined program of arterial hypertension development, seemingly delaying it and alleviating the negative consequences in respect to the target organs, through increased effectiveness of recruitment of adaptive-compensatory organism reserves, however, on the whole, it did not interrupt this program.
Shmerling
M D
MD
Buzueva
I I
II
Korostyshevskaia
I M
IM
Lazarev
V A
VA
Maksimov
V F
VF
Filiushina
E E
EE
Markel'
A L
AL
Iakobson
G S
GS
D000311:Adrenal Glands / Q000254:growth & development / Q000648:ultrastructure*; D000818:Animals; D000833:Animals, Suckling; D005247:Feeding Behavior; D005260:Female; D006321:Heart / Q000254:growth & development; D006973:Hypertension / Q000209:etiology* / Q000235:genetics; D007678:Kidney Glomerulus / Q000254:growth & development / Q000648:ultrastructure*; D009206:Myocardium / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000150:complications* / Q000235:genetics