title: [Alveolar echinococcosis].
abstract: Alveolar echinococcosis is a serious parasitic disease, leading to large hepatic lesions. It must be distinguished from cystic echinococcosis, or hydatic cyst, caused by Echinococcus granulosus. Early diagnosis may allow surgical removal of the lesions by segmental hepatectomy, the only curative treatment. Parasitostatic medical treatment with albendazole may promote stabilization of the disease. Until recently, Belgium was considered a country at very low risk for alveolar echinococcosis, as no human case was reported, despite up to 51% of fox infection in southern Belgium autopsy series. Recently four patients presented with alveolar echinococcosis at the University Hospital Center of Liege, leading to the fear of a possible alveolar echinococcosis endemy in southern Belgium. Two of these patients underwent curative hepatectomy, but the other two had already pulmonary metastases at diagnosis and received palliative albendazole therapy. This article presents these cases, and reviews the clinical features of this parasitic disease.
authors.affiliation: Service de Chirurgie Abdominale, Endocrine et de Transplantation, CHU, Liége.
authors.forename: O
authors.initials: O
authors.lastname: Wauters
authors.forename: C
authors.initials: C
authors.lastname: Honoré
authors.forename: O
authors.initials: O
authors.lastname: Detry
authors.forename: J
authors.initials: J
authors.lastname: Delwaide
authors.forename: J
authors.initials: J
authors.lastname: Demonty
authors.forename: P
authors.initials: P
authors.lastname: Léonard
authors.forename: A
authors.initials: A
authors.lastname: Thiry
authors.forename: M P
authors.initials: MP
authors.lastname: Hayette
authors.forename: A
authors.initials: A
authors.lastname: De Roover
authors.forename: P
authors.initials: P
authors.lastname: Honoré
authors.forename: J
authors.initials: J
authors.lastname: Boniver
authors.forename: J
authors.initials: J
authors.lastname: Belaïche
authors.forename: M
authors.initials: M
authors.lastname: Meurisse
mesh_terms: D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000871:Anthelmintics / Q000627:therapeutic use; D001530:Belgium; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000150:complications / Q000601:surgery; D004445:Echinococcosis, Pulmonary / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015047:Zoonoses
chemical_list: D000871:Anthelmintics; D015766:Albendazole