title: L-Isoleucyl-L-serine 0.33-hydrate, L-phenylalanyl-L-serine and L-methionyl-L-serine 0.34-hydrate.
abstract: The structures of the title dipeptides, C9H18N2O4.0.33H2O, C12H16N2O4 and C8H16N2O4S.0.34H2O, complete a series of investigations focused on L-Xaa-L-serine peptides, where Xaa is a hydrophobic residue. All three structures are divided into hydrophilic and hydrophobic layers. The hydrophilic layers are thin for L-phenylalanyl-L-serine, rendered possible by an unusual peptide conformation, and thick for L-isoleucyl-L-serine and L-methionyl-L-serine, which include cocrystallized water molecules on the twofold axes.
authors.affiliation: Department of Chemistry, University of Oslo, PO Box 1033, Blindern, N-0315 Oslo, Norway. c.h.gorbitz@kjemi.uio.no
authors.forename: Carl Henrik
authors.initials: CH
authors.lastname: Görbitz
authors.forename: Marius
authors.initials: M
authors.lastname: Bruvoll
authors.forename: Selma
authors.initials: S
authors.lastname: Dizdarevic
authors.forename: Nina
authors.initials: N
authors.lastname: Fimland
authors.forename: Jasmina
authors.initials: J
authors.lastname: Hafizovic
authors.forename: Helen Therese
authors.initials: HT
authors.lastname: Kalfjøs
authors.forename: Alexander
authors.initials: A
authors.lastname: Krivokapic
authors.forename: Kristian
authors.initials: K
authors.lastname: Vestli
mesh_terms: D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure
chemical_list: D004151:Dipeptides; C025275:phenylalanylserine