title: The effects of acetylsalicylic acid on the pituitary prolactin of the lizard, Uromastix hardwickii.
abstract: This study deals with the intravenous administration of 7 mg acetylsalicylic acid (ASA) solution to Uromastix hardwickii for 4 days. It enhances the activity of anterior pituitary lactotrophs, when 0.1 ml of pituitary homogenate of ASA treated was injected hypodermically to crop-sac showed a greater diametric response and increased activity with milk like secretion than that of the injections of 0.1 ml homogenate of control pituitary. The present study indicated that ASA induces hyperprolactinemia.
authors.affiliation: Department of Physiology, University of Karachi, Karachi-75270, Pakistan.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Ahmad
authors.forename: Ruqaiya
authors.initials: R
authors.lastname: Hasan
authors.forename: Mansoor
authors.initials: M
authors.lastname: Ahmad
authors.forename: Anila
authors.initials: A
authors.lastname: Qureshi
authors.forename: Shama
authors.initials: S
authors.lastname: Masroor
mesh_terms: D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D008116:Lizards; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism; D011388:Prolactin / Q000378:metabolism*; D011453:Prostaglandins / Q000502:physiology
chemical_list: D016861:Cyclooxygenase Inhibitors; D011453:Prostaglandins; D011388:Prolactin; D001241:Aspirin