title: Laparoscopic adrenalectomy of an adrenal adenoma with myelolipoma relieves severe hypertension in a 16-year-old patient.
abstract: Adrenal adenoma with myelolipoma is extremely rare in pediatrics. Although the tumor is usually asymptomatic, sometimes it may result in serious manifestations. A 16-year-old patient was diagnosed with severe hypertension associated with a right adrenal mass. The laboratory work-up was inconclusive of the nature of the tumor. Plasma and urinary hormonal studies were not diagnostic. Magnetic resonance imaging (MRI) of the brain and meta-iodobenzylguanidine (MIBG) scanning were normal. MRI of the abdomen showed a heterogeneous adrenal mass 4.2x3.3 cm. Laparoscopic resection of the mass was done, and the pathology revealed an adrenal adenoma with myelolipoma. After tumor resection the hypertension resolved, and within 1 month the patient was off medications. At 2-year follow-up the patient's blood pressure remained normal at 120/73 mmHg. This is a case in which an adrenal adenoma with myelolipoma, a benign and usually asymptomatic tumor, presented as severe hypertension resolving with surgical resection of the tumor.
authors.affiliation: Endocrinology Section, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Rana F
authors.initials: RF
authors.lastname: Ammoury
authors.forename: Rubina A
authors.initials: RA
authors.lastname: Heptulla
authors.forename: Nina
authors.initials: N
authors.lastname: Tatevian
authors.forename: Ewa
authors.initials: E
authors.lastname: Elenberg
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D000315:Adrenalectomy; D018246:Adrenocortical Adenoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D010535:Laparoscopy; D008297:Male; D018209:Myelolipoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000601:surgery*