title: Are semantic deficits in schizophrenia due to problems with access or storage?
abstract: Semantic processing deficits are central to cognitive abnormalities in schizophrenia. Such semantic deficits may be related to either poor access or poor storage of semantic knowledge. 32 schizophrenia patients and 32 matched normal controls performed five semantic processing tasks that examined item-specific consistency over time, the word frequency effect and semantic priming. A subgroup of patients performed tasks on three separate occasions. It is generally assumed that a storage deficit is signalled by item-specific consistent performance, an exaggerated effect of word frequency, and the occurrence of hyperpriming; an access deficit is signalled by the absence of these effects. The data demonstrated item-specific consistency, a frequency effect and significant hyperpriming. The pattern is consistent with a storage deficit of semantic memory in schizophrenia.
authors.affiliation: Macquarie Centre for Cognitive Science (MACCS), Macquarie University, Sydney, NSW 2109, Australia. srossell@mhri.edu.au
authors.forename: Susan L
authors.initials: SL
authors.lastname: Rossell
authors.forename: Anthony S
authors.initials: AS
authors.lastname: David
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis* / Q000523:psychology; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D010153:Paired-Associate Learning; D011930:Reaction Time; D012153:Retention, Psychology; D012559:Schizophrenia / Q000175:diagnosis*; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D012660:Semantics; D014706:Verbal Learning