title: Esophageal squamous cell carcinoma after liver transplantation.
abstract: The occurrence of an oesophageal squamous cell carcinoma following liver transplantation is very infrequent. Such an event has been related to a history of alcohol-induced cirrhosis, as in other squamous cell tumours of the oropharynx. We report the case of a 64-year-old male patient diagnosed as having oesophageal squamous cell carcinoma six years after having had a liver transplant due to alcohol-induced cirrhosis. The tumour was treated surgically and consisted of an Ivor-Lewis oesophagectomy. The patient is disease-free 17 months after surgery. A review of the cases reported in the literature indicated treatment with chemotherapy and radiation therapy, and with excision in some cases. Generally, despite aggressive treatment the prognosis is poor.
authors.affiliation: Unidad de Cirugía Esófago-Gástrica, Servicio de Cirugía General, Hospital Virgen del Camino, Pamplona, Navarra, Spain. adiazdea@cfnavarra.es
authors.forename: Alvaro
authors.initials: A
authors.lastname: Díaz de Liaño
authors.forename: Cristina
authors.initials: C
authors.lastname: Artieda
authors.forename: Concepción
authors.initials: C
authors.lastname: Yárnoz
authors.forename: Carlos
authors.initials: C
authors.lastname: Garde
authors.forename: Laura
authors.initials: L
authors.lastname: Flores
authors.forename: Héctor
authors.initials: H
authors.lastname: Ortiz
mesh_terms: D000437:Alcoholism / Q000150:complications*; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000601:surgery; D002299:Cardia / Q000473:pathology* / Q000601:surgery; D003680:Deglutition Disorders / Q000209:etiology; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000601:surgery; D004940:Esophageal Stenosis / Q000209:etiology; D016629:Esophagectomy; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008104:Liver Cirrhosis, Alcoholic / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000209:etiology* / Q000601:surgery; D016559:Tacrolimus / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus