title: Design and synthesis of a quinazolinone natural product-templated library with cytotoxic activity.
authors.affiliation: ArQule, Inc., 19 Presidential Way, Woburn, Massachusetts 01801, USA. jliu@arqule.com
authors.forename: Ji-Feng
authors.initials: JF
authors.lastname: Liu
authors.forename: Mira
authors.initials: M
authors.lastname: Kaselj
authors.forename: Yuko
authors.initials: Y
authors.lastname: Isome
authors.forename: Ping
authors.initials: P
authors.lastname: Ye
authors.forename: Katie
authors.initials: K
authors.lastname: Sargent
authors.forename: Kevin
authors.initials: K
authors.lastname: Sprague
authors.forename: Djamel
authors.initials: D
authors.lastname: Cherrak
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Wilson
authors.forename: Ying
authors.initials: Y
authors.lastname: Si
authors.forename: Daniel
authors.initials: D
authors.lastname: Yohannes
authors.forename: Shi-Chung
authors.initials: SC
authors.lastname: Ng
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000970:Antineoplastic Agents; D011799:Quinazolines