title: [Management of primary HIV-infection].
abstract: Clinical suspicion of a primary HIV infection is aroused by the patient's exposure history and can only be confirmed by an HIV PCR test. The classic HIV antibody test (ELISA) often is non-reactive during the very early stage of HIV infection. The value of antiviral therapy during primary HIV infection is unclear. In spite of a positive influence on surrogate markers in vitro, studies so far have not been able to demonstrate a clinical benefit. Treatment should be carried out only in specialized infectious disease centers, most preferably within controlled clinical studies.
authors.affiliation: Facharzt für Innere Medizin, Praxis St. Georg, Hamburg. schewe@praxis-st-georg.de
authors.forename: C K
authors.initials: CK
authors.lastname: Schewe
mesh_terms: D015492:AIDS Serodiagnosis; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016516:CD4-CD8 Ratio; D042241:Early Diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D006679:HIV Seropositivity / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents