Stem cell research goes underground: the RETINOBLASTOMA-RELATED gene in root development.
Both cellular differentiation and stem cell maintenance must occur at the root apex in order to ensure the continuous growth of plant roots. In this issue of Cell, it is revealed that a canonical retinoblastoma pathway plays a crucial role in regulating the balance between differentiation and renewal of plant root stem cells.
Dinneny
José R
JR
Department of Biology, Duke University, Durham, NC 27708, USA.
Benfey
Philip N
PN
D017360:Arabidopsis / Q000166:cytology*; D002454:Cell Differentiation / Q000502:physiology; D018517:Plant Roots / Q000166:cytology* / Q000254:growth & development*; D016160:Retinoblastoma Protein / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology*
D016160:Retinoblastoma Protein