Design and synthesis of a quinazolinone natural product-templated library with cytotoxic activity.
Liu
Ji-Feng
JF
ArQule, Inc., 19 Presidential Way, Woburn, Massachusetts 01801, USA. jliu@arqule.com
Kaselj
Mira
M
Isome
Yuko
Y
Ye
Ping
P
Sargent
Katie
K
Sprague
Kevin
K
Cherrak
Djamel
D
Wilson
Christopher J
CJ
Si
Ying
Y
Yohannes
Daniel
D
Ng
Shi-Chung
SC
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000470:Alkaloids; D000970:Antineoplastic Agents; D011799:Quinazolines