title: Dihydrotrichodimerol and tetrahydrotrichodimerol, two new bisorbicillinoids, from a marine-derived Penicillium terrestre.
abstract: Two new bisorbicillinoids possessing an open-ended cage structure, dihydrotrichodimerol (1) and tetrahydrotrichodimerol (2), were isolated from a marine-derived Penicillium terrestre. Their structures were established by spectroscopic methods. Their cytotoxic activities against P388 and A-549 cell lines were preliminarily evaluated by the MTT method.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, PR China.
authors.forename: Weizhong
authors.initials: W
authors.lastname: Liu
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
authors.forename: Chengbin
authors.initials: C
authors.lastname: Cui
authors.forename: Guotao
authors.initials: G
authors.lastname: Fan
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D008386:Marine Biology; D010407:Penicillium / Q000737:chemistry*
chemical_list: D001952:Bridged-Ring Compounds; C473619:bisorbicillinolide; C508028:tetrahydrotrichodimerol