Affinity prediction for substrates of the peptide transporter PepT1.
A quantitative method has been developed for determining the affinity of substrates for the peptide transporter PepT1, allowing oral availability of drugs via PepT1 to be estimated.
Bailey
Patrick D
PD
School of Chemistry, Faraday Building, University of Manchester, Sackville Street, Manchester, UK M60 1QD. pat.bailey@manchester.ac.uk
Boyd
C A Richard
CA
Collier
Ian D
ID
George
John P
JP
Kellett
George L
GL
Meredith
David
D
Morgan
Keith M
KM
Pettecrew
Rachel
R
Price
Richard A
RA
D000465:Algorithms; D001665:Binding Sites; D001692:Biological Transport; D015394:Molecular Structure; D000074011:Peptide Transporter 1; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D013379:Substrate Specificity; D027981:Symporters / Q000737:chemistry* / Q000378:metabolism
D000074011:Peptide Transporter 1; D010455:Peptides; D027981:Symporters