title: Progression of peripheral anterior synechiae after laser iridotomy.
abstract: OBJECTIVE
  To determine the incidence and to characterize the risk factors of peripheral anterior synechiae (PAS) progression after laser iridotomy (LI).
  
  
  METHODS
  Retrospective observational cohort study.
  
  
  METHODS
  The extents of pre- and postlaser PAS and ocular and systemic data were obtained from the charts of 54 primary angle-closure glaucoma patients (59 eyes), all of whom had undergone LI.
  
  
  RESULTS
  PAS progressed in 19 of the 59 eyes (32.2%), during a mean follow-up period of 34.4 months (range, 6-95 months). Multivariate analysis showed that the presence of plateau iris (P = .024), and a high intraocular pressure 1 hour before LI (P = .042) were risk factors of PAS progression.
  
  
  CONCLUSIONS
  Approximately one of three of the eyes showed PAS progression during a 3-year follow-up period after LI. The probability of progression was found to be higher in the eyes that exhibited plateau iris and in eyes that proved to be relatively unresponsive to medication before LI.
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Guro Hospital, 97 Gurodong-gil, Guro-gu, Seoul 152-703, South Korea.
authors.forename: Jun Sung
authors.initials: JS
authors.lastname: Choi
authors.forename: Yong Yeon
authors.initials: YY
authors.lastname: Kim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D032801:Iridectomy; D007498:Iris / Q000601:surgery; D007499:Iris Diseases / Q000175:diagnosis*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D000267:Tissue Adhesions; D014129:Trabecular Meshwork / Q000473:pathology*