title: Clinical profile of forefoot eczema: a study of 42 cases.
abstract: BACKGROUND
  Forefoot eczema (FE) is characterized by dry fissured dermatitis of the plantar surface of the feet.
  
  
  OBJECTIVE
  To study the clinical profile of FE and the possible etiological factors.
  
  
  METHODS
  Forty-two patients with FE were included in the study. A detailed history was recorded and examination done. Fungal scrapings and patch test with Indian Standard Series (ISS) were performed in all patients.
  
  
  RESULTS
  The most common site affected was the plantar surface of the great toe in 16 (38.09%) patients. Hand involvement, with fissuring and soreness of the fingertips and palm, was seen in four patients (9.5%). Seven patients (16.6%) had a personal history of atopy whereas family history of atopy was present in six (14.2%). Seven patients (16.6%) reported aggravation of itching with plastic, rubber or leather footwear, and 13 (30.9%), with detergents and prolonged contact with water. Negative fungal scrapings in all patients ruled out a dermatophyte infection. Patch testing with ISS was performed in 19 patients and was positive in five.
  
  
  CONCLUSIONS
  FE is a distinctive dermatosis of the second and third decade, predominantly in females, with a multifactorial etiology, possible factors being chronic irritation, atopy, footwear and seasonal influence.
authors.affiliation: Department of Skin and STD, Kasturba Medical College, Manipal, India.
authors.forename: Kamal Jeet
authors.initials: KJ
authors.lastname: Brar
authors.forename: S D
authors.initials: SD
authors.lastname: Shenoi
authors.forename: C
authors.initials: C
authors.lastname: Balachandran
authors.forename: Vandana Rai
authors.initials: VR
authors.lastname: Mehta
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000453:epidemiology; D003879:Dermatologic Agents / Q000627:therapeutic use; D003881:Dermatomycoses / Q000175:diagnosis* / Q000453:epidemiology; D004485:Eczema / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D005533:Foot Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005545:Forefoot, Human; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D010328:Patch Tests; D011379:Prognosis; D018570:Risk Assessment; D012494:Sampling Studies; D017678:Sex Distribution; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents