Propensity scores and the surgeon.
BACKGROUND
Evidence-based surgery has been established as a cornerstone of good clinical practice, promising to improve the treatment of patients and the quality of surgical education. However, evidence-based surgery requires dedicated clinicians trained to perform methodologically sound clinical investigations. Statistical knowledge is therefore invaluable. Surgical studies often cannot be randomized. Propensity scores offer a powerful alternative to multivariable analysis in the assessment of observational, non-randomized surgical studies. Unfortunately, many surgeons are unaware of this important analytical approach that has gained increasing stature in medical research. Thus, propensity score analyses are not used often in surgical studies.


OBJECTIVE
The purpose of this paper is to provide a comprehensive overview of propensity score analysis, allowing the surgeon to understand the role, advantages and limitations of propensity scores, boosting their development in surgical investigations.
Adamina
M
M
Division of General Surgery and Institute for Surgical Research and Hospital Management, University of Basel, Hebelstrasse 20, CH-4031 Basel, Switzerland.
Guller
U
U
Weber
W P
WP
Oertli
D
D
D015986:Confounding Factors, Epidemiologic; D019317:Evidence-Based Medicine; D013502:General Surgery / Q000592:standards*; D006801:Humans; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011379:Prognosis; D012044:Regression Analysis