The role of Hsp70 in age-related diseases and the prevention of cancer.
This article focuses on the structure, function, mode of action of one of the major heat shock proteins, Hsp70, and its implication in age-related diseases and cancer.
Pierpaoli
Ezra V
EV
Chemin du Verger 16, 1752 Villars-sur-Glâne, Switzerland. epierpaoli@hotmail.com
D000375:Aging / Q000502:physiology*; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D019496:Cancer Vaccines; D018840:HSP70 Heat-Shock Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008958:Models, Molecular; D018832:Molecular Chaperones / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism / Q000517:prevention & control; D019636:Neurodegenerative Diseases / Q000378:metabolism; D017510:Protein Folding; D017434:Protein Structure, Tertiary
D001426:Bacterial Proteins; D019496:Cancer Vaccines; D018840:HSP70 Heat-Shock Proteins; D018832:Molecular Chaperones