[Analytical profile of 1-(4-fluorophenyl)-4-[3-(3-propoxyphenylcarbamoyloxy)-2-hydroxypropyl]piperazinium chloride (6f)].
The paper presents the results of an analytical evaluation and a study of some physicochemical properties of a potential antiarrhythmic agent marked as 6f. The melting point, spectral properties, solubility and chromatographic behaviour of the drug on the thin layer were investigated. For the content determination, spectrophotometry in the ultraviolet region of the spectrum at the wavelength of the second absorption maximum of the substance and high-performance liquid chromatography were used.
Sedlárová
E
E
Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra farmaceutickej chémie. sedlarova@fpharm.uniba.sk
Malík
I
I
Csollei
J
J
Andriamanty
F
F
D000889:Anti-Arrhythmia Agents / Q000032:analysis*; D002845:Chromatography; D010879:Piperazines / Q000032:analysis*; D013057:Spectrum Analysis
C508123:1-(4-fluorophenyl)-4-(3-(3-propoxyphenylcarbamoyloxy)-2-hydroxypropyl)piperazinium chloride; D000889:Anti-Arrhythmia Agents; D010879:Piperazines