title: Extramammary Paget's disease.
abstract: Two patients with extramammary Paget's disease are being reported. The first case was a 60-year-old male who presented with gradually progressive pruritic ulcerated lesion over perianal region not responding to various topical medications. Dermatological examination revealed a large erythematous sharply marginated scaly plaque in the perianal region extending into the anal canal, covered with grayish crusts and shallow erosions. Skin biopsy from the lesion was suggestive of Paget's disease. The second patient, a 60-year-old male, with a three year long history, presented with similar lesions and findings. Skin biopsy in this case was also consistent with Paget's disease. These two cases of extramammary Paget's disease involving the perianal region are being reported because of their rarity and also to stress the fact that a high degree of suspicion is needed for the diagnosis of this uncommon disease entity.
authors.affiliation: Military Hospital, Jodhpur, Rajasthan, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Banerjee
authors.forename: Manas
authors.initials: M
authors.lastname: Chatterjee
authors.forename: Kailash
authors.initials: K
authors.lastname: Chand
mesh_terms: D000368:Aged; D001004:Anus Diseases / Q000473:pathology*; D004817:Epidermis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*