title: Fluctuations of biochemical constituents and marker enzymes as a consequence of naphthalene toxicity in the edible estuarine crab Scylla serrata.
abstract: The sublethal effects of naphthalene on protein, deoxyribonucleic acid (DNA), ribonucleic acid (RNA), carbohydrates, lipids, and certain marker enzymes such as phosphatases, transaminases, and lactate dehydrogenase were studied in hepatopancreas, hemolymph, and ovary in the edible crab Scylla serrata. The results revealed that there was overall decrease in total protein, total DNA, total RNA, free sugar, glycogen, protein-bound sugars, neutral lipid, glycolipid, and phospholipid in the test samples compared to control. Similarly all the marker enzymes (acid phosphatase, alkaline phosphatase, aspartate transaminase, alanine transaminase, and lactate dehydrogenase) were decreased in hepatopancreas and ovary. On the other hand, in hemolymph, the activities of marker enzymes were increased. The results were tested statistically and interpreted accordingly.
authors.affiliation: Department of Pharmacology and Environmental Toxicology, Dr. ALM-Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai 600 113, Tamil Nadu, India. viji222@rediffmail.com
authors.forename: K
authors.initials: K
authors.lastname: Vijayavel
authors.forename: M P
authors.initials: MP
authors.lastname: Balasubramanian
mesh_terms: D000818:Animals; D015415:Biomarkers; D003386:Brachyura / Q000187:drug effects* / Q000378:metabolism; D002241:Carbohydrates / Q000032:analysis; D004247:DNA / Q000032:analysis; D005260:Female; D006458:Hemolymph / Q000201:enzymology / Q000378:metabolism; D043143:Hepatopancreas / Q000201:enzymology / Q000378:metabolism; D007928:Lethal Dose 50; D008055:Lipids / Q000032:analysis; D009281:Naphthalenes / Q000633:toxicity*; D010053:Ovary / Q000201:enzymology / Q000378:metabolism; D011506:Proteins / Q000032:analysis; D012313:RNA / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D002241:Carbohydrates; D008055:Lipids; D009281:Naphthalenes; D011506:Proteins; D014874:Water Pollutants, Chemical; C031721:naphthalene; D012313:RNA; D004247:DNA