title: Association of increased body mass index and impaired endothelial function among Hispanic women.
abstract: We tested the hypothesis that an increased body mass index was similarly associated with impaired endothelial function as measured by flow-mediated dilation in a high-risk, Hispanic population of men and women living in northern Manhattan. The association of flow-mediated dilation and body mass index was significant in women (beta -0.16 +/- 0.04, p <0.0001) but not in men (beta -0.02 +/- 0.06, p = 0.72). This is the first study to demonstrate a gender-specific difference in endothelial function associated with body mass index.
authors.affiliation: Department of Medicine, Division of Cardiology, Columbia University, New York, New York, USA.
authors.forename: Todd
authors.initials: T
authors.lastname: Pulerwitz
authors.forename: Cairistine
authors.initials: C
authors.lastname: Grahame-Clarke
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Rodriguez
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Miyake
authors.forename: Robert R
authors.initials: RR
authors.lastname: Sciacca
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hirata
authors.forename: Marco R
authors.initials: MR
authors.lastname: DiTullio
authors.forename: Bernadette
authors.initials: B
authors.lastname: Boden-Albala
authors.forename: Ralph L
authors.initials: RL
authors.lastname: Sacco
authors.forename: Shunichi
authors.initials: S
authors.lastname: Homma
mesh_terms: D000367:Age Factors; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D016014:Linear Models; D008297:Male; D015999:Multivariate Analysis; D009765:Obesity / Q000503:physiopathology*; D012737:Sex Factors; D014463:Ultrasonography; D014664:Vasodilation / Q000502:physiology*