Connexin 43 signalling and cardioprotection.
Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial Cx43 in protection by IP is reviewed.
Boengler
K
K
Institut für Pathophysiologie, Universitätsklinikum Essen, Essen, Germany.
Schulz
R
R
Heusch
G
G
D002450:Cell Communication / Q000502:physiology*; D018031:Connexin 43 / Q000502:physiology*; D006801:Humans; D019157:Ischemic Preconditioning, Myocardial; D008928:Mitochondria / Q000502:physiology*
D018031:Connexin 43