Hepatitis D.
Hepatitis D virus (HDV) is a small, RNA-containing virus that requires the concomitant presence of Hepatitis B virus (HBV) in an obligate manner for its survival and pathogenicity. HDV infection is very uncommon in Czech Republic. The results of antiviral therapy of hepatitis D patients are not satisfactory. Alpha-interferon (alpha-IFN) in high doses (9-10 MU three times a week for 12 months) is usually recommended.
Husa
P
P
Department of Infectious Diseases, University Hospital Brno, Jihlavska 20, 625 00 Brno, Czech Republic. phusa@med.muni.cz
Linhartová
A
A
Nemecek
V
V
Husová
L
L
D000998:Antiviral Agents / Q000627:therapeutic use; D006509:Hepatitis B / Q000150:complications; D003699:Hepatitis D / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D003698:Hepatitis Delta Virus / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D008954:Models, Biological
D000998:Antiviral Agents; D016898:Interferon-alpha