title: Adverse obstetric outcome in women with a history of infertility: a retrospective study.
abstract: Women with a history of infertility are associated with a higher incidence of adverse pregnancy outcome. This retrospective study reviewed 105 women with a known history of infertility; of these 105 women, 77 (73%) conceived spontaneously and 28 (27%) had assisted conception. Our finding confirms higher perinatal complications; relative ratios (RR) for pre-eclampsia was 4.6 (95% CI=2.1-9.9), intrauterine growth restriction 4.8 (95% CI=1.9-12.0), gestational diabetes 1.8 (95% CI=0.5-5.8), pre-term premature rupture of membrane 2.3 (95% CI=0.6-8.8) and pre-term labour 2.6 (95% CI=1.1-5.9). We postulate that women with a history of infertility are at high risk of such obstetric complications and may benefit from intensified antenatal care.
authors.affiliation: Department of Obstetrics and Gynaecology, Stafford General Hospital, Stafford, UK. hyasmin24@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Yasmin
authors.forename: I
authors.initials: I
authors.lastname: Hassan
authors.forename: P
authors.initials: P
authors.lastname: Vanga
authors.forename: M
authors.initials: M
authors.lastname: Subramanium
authors.forename: J H
authors.initials: JH
authors.lastname: Adeghe
mesh_terms: D000328:Adult; D005260:Female; D005306:Fertilization; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000209:etiology*; D011256:Pregnancy Outcome / Q000453:epidemiology; D011295:Prenatal Care; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies; D006113:United Kingdom / Q000453:epidemiology