Melatonin influences on the neuroendocrine-reproductive axis.
The neuroendocrine-reproductive axis designates the functional activity of the hypothalamus-pituitary-gonadal axis. A delicate synchronization of many inputs at these three different levels is vital for normal reproductive function. From the median basal hypothalamus, the median eminence releases gonadotrophin releasing hormone into the portal circulation to reach the anterior pituitary gland. Gonadotrophin releasing hormone is obviously a key hormone for the regulation of the secretion of gonadotrophins LH and FSH.
Díaz López
Beatriz
B
Departamento de Biología Funcional, Area Fisiología, Facultad de Medicina, Universidad de Oviedo. C /Julián Clavería, 6. 33006 Oviedo, Spain. beatrizd@uniovi.es
Díaz Rodríguez
E
E
Urquijo
Colmenero
C
Fernández Alvarez
C
C
D000375:Aging / Q000502:physiology; D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D025461:Feedback, Physiological; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism; D006066:Gonads / Q000502:physiology*; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007986:Luteinizing Hormone / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D009865:Oocytes / Q000502:physiology; D010870:Pineal Gland / Q000502:physiology; D010902:Pituitary Gland / Q000502:physiology; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D012741:Sexual Maturation / Q000502:physiology*; D015320:Tachykinins / Q000378:metabolism
D012739:Gonadal Steroid Hormones; D015320:Tachykinins; D007987:Gonadotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D008550:Melatonin