title: Central corneal thickness and development of glaucomatous optic disk hemorrhages.
abstract: OBJECTIVE
  To evaluate whether central corneal thickness influences the development of optic disk hemorrhages in chronic open-angle glaucoma.
  
  
  METHODS
  Prospective observational clinical study.
  
  
  METHODS
  The study included 390 eyes of 223 white subjects with chronic open-angle glaucoma observed during a mean follow-up time of 61.3 +/- 36.4 months. Central corneal thickness was measured by corneal pachymetry.
  
  
  RESULTS
  The event of optic disk hemorrhages during follow-up was detected in 63 eyes (16.2%). Development of optic disk hemorrhages was, univariately (P = .73) as well as in a multiple Cox regression analysis, controlling for age, sex, normal tension glaucoma, intraocular pressure, neuroretinal rim area, and size of beta zone of peripapillary atrophy, statistically independent (P = .56) of central corneal thickness.
  
  
  CONCLUSIONS
  Development of optic disk hemorrhages may not be markedly influenced by central corneal thickness.
authors.affiliation: Department of Ophthalmology and Eye Hospital, University Erlangen-Nürnberg, Erlangen, Germany. Jost.Jonas@augen.ma.uni-heidelberg.de
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
authors.forename: Andrea
authors.initials: A
authors.lastname: Stroux
authors.forename: Isabel M
authors.initials: IM
authors.lastname: Oberacher-Velten
authors.forename: Naris
authors.initials: N
authors.lastname: Kitnarong
authors.forename: Anselm
authors.initials: A
authors.lastname: Juenemann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003315:Cornea / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D011446:Prospective Studies; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000209:etiology; D012307:Risk Factors