[Chronic lead intoxication associated with Ayurvedic medication].
A 46-year-old man with multiple sclerosis had severe generalised pain for which treatment with paracetamol, ibuprofen, gabapentin and methyl-prednisolone had been unsuccessful. In addition normocytic anaemia without haemolysis and with a normal iron load was found. Due to bright red rectal blood loss and nausea, vomiting, weight loss, anorexia, abdominal pain and constipation a colonoscopy was planned. However, before this was performed, manual slide differentiation of a blood smear showed basophilic stippling and it turned out that the patient had been taking Ayurvedic medication up to one month before presentation. A moderately severe lead intoxication was diagnosed: 0.77 mg/l. The herbal medication had a very high lead content. The patient was successfully treated with the oral lead chelator 23-dimercaptosuccinic acid. Traditional and folk remedies often are important causes of lead poisoning.
Kanen
B L J
BL
VU Medisch Centrum, Postbus 7057, 1007 MB Amsterdam. boris.kanen@vumc.nl
Perenboom
R M
RM
D015913:Chelation Therapy / Q000379:methods; D006801:Humans; D007855:Lead Poisoning / Q000175:diagnosis* / Q000209:etiology*; D008297:Male; D008515:Medicine, Ayurvedic; D008875:Middle Aged; D016896:Treatment Outcome