Investigations of the Malagasy species Tachiadenus longiflorus Grisebach (Gentianaceae): linking chemical finding and traditional usage.
A decoction of the aerial parts of Tachiadenus longiflorus, a Gentianaceae endemic to Madagascar, is drunk to relieve stomach pains and dyspepsia; while a leaf decoction is drunk as a purgative or to relieve gall bladder ailments in folk medicine in Madagascar. The stem and bark have yielded a large amount of the triterpenoid, oleanolic acid, and the coumarins, scoparone and scopoletin. These compounds have been isolated previously from other sources and have shown broad pharmacological properties. We report the possible link between the compounds isolated and the traditional use of Tachiadenus longiflorus.
Randrianarivelojosia
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Malaria Research Group, BP 1274, Antananarivo, 101, Institut Pasteur de Madagascar, Madagascar. milijaon@pasteur.mg
Langlois
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A
Mulholland
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DA
D029965:Gentianaceae / Q000737:chemistry*; D008270:Madagascar; D008519:Medicine, Traditional; D008517:Phytotherapy