A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates.
Fokkens
Jasmine
J
Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Germany.
Klebe
Gerhard
G
D002151:Calorimetry; D018360:Crystallography, X-Ray; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry; D015842:Serine Proteinase Inhibitors / Q000737:chemistry; D013237:Stereoisomerism; D013917:Thrombin / Q000737:chemistry / Q000378:metabolism; D014357:Trypsin / Q000737:chemistry / Q000378:metabolism
D011506:Proteins; D015842:Serine Proteinase Inhibitors; D014357:Trypsin; D013917:Thrombin