title: Non-ablative 1,450-nm diode laser treatment of striae distensae.
abstract: OBJECTIVE
  Striae distensae are dermal scars with flattening and atrophy of the epidermis. Successful treatment of these stretch marks has been disappointing. The non-ablative 1,450-nm diode laser has been shown to improve atrophic scars and may be expected to improve striae. As yet, no study has been published to document the effects of this laser on striae. Our aim is to evaluate the efficacy of the 1,450-nm diode laser in the treatment of striae rubra and striae alba in Asian patients with skin types 4-6.
  
  
  METHODS
  Striae on one half of the body in 11 patients were treated with the 1,450-nm diode laser with cryogen cooling spray with the other half serving as a control. The following parameters were used: 6 mm spot size and dynamic cooling device (DCD) for 40 milliseconds to protect the epidermis. Patients were randomly assigned to receive either 4, 8, or 12 J/cm2. A total of three treatments were given at 6-week intervals. The following sites were treated: abdomen, arms, back, buttocks, and thighs. Two patients had striae rubra and nine striae alba. Clinical photographs were taken before and after each treatment and analysis was undertaken through photographic evaluation by non-treating physicians.
  
  
  RESULTS
  At 2 months after the last treatment, no patients showed any noticeable improvement in the striae on the treated side compared to baseline and to the control areas. Side effects were limited to transient erythema and postinflammatory hyperpigmentation (PIH), which occurred in seven (64%) patients.
  
  
  CONCLUSIONS
  The non-ablative 1,450-nm diode laser is not useful in the treatment of striae in patients with skin types 4, 5, and 6.
authors.affiliation: Division of Dermatology, Changi General Hospital, 2 Simei Street 3, Singapore. yong_kwang_tay@cgh.com.sg
authors.forename: Yong-Kwang
authors.initials: YK
authors.lastname: Tay
authors.forename: Colin
authors.initials: C
authors.lastname: Kwok
authors.forename: Eileen
authors.initials: E
authors.lastname: Tan
mesh_terms: D000328:Adult; D044466:Asian People; D002921:Cicatrix / Q000628:therapy*; D020405:Dermis / Q000528:radiation effects*; D004817:Epidermis / Q000528:radiation effects; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology; D053685:Laser Therapy / Q000009:adverse effects; D008297:Male; D016896:Treatment Outcome