[The colicynogenic activity and anthibiotic sensitivity of collected and newly isolated strains of Shigella flexneri and Shigella sonnei].
Among the collection strains of S. flexneri 10.5; 5.5; 2.6; 2.6 and 7.9% of strains were resistant to ampicillin, tetracycline, ceftryaxon, cefasoline, chloramphenycol, respectively. The maximum number of R-determinants of one strain was 4. The strains resistant to cefalosporynes were not revealed; among newly isolated strains of this agent, these strains resistant to ampicilline, tetracycline and chloramphenycol made 20%. Among the collection and newly isolated strains of S. flexneri, isolated 50 and more years ago, the part of colicinogenic ones was 10%. And, on the contrary both for the collection and newly isolated strains of S. sonnei colicinogenic activity is specific biological property (above 80%). Correlation relation between two tested pathogenic factors, certain serovars and biovars of the agents, was not revealed.
Koltukova
N V
NV
Serebriakova
T L
TL
Ianovs'ka
V V
VV
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003087:Colicins / Q000096:biosynthesis*; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D048168:Escherichia coli K12 / Q000378:metabolism; D012763:Shigella flexneri / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism; D012764:Shigella sonnei / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003087:Colicins