title: Amiodarone toxicity presenting as pulmonary mass and peripheral neuropathy: the continuing diagnostic challenge.
abstract: A 64 year old man receiving long term amiodarone treatment presented with dyspnea, cough, and weight loss. Radiographs and computed tomography showed a lung mass with associated multiple pulmonary nodules. Biopsies of the pulmonary mass showed foamy histiocytes without malignant cells. However, findings on FDG-PET scan were consistent with a malignant tumour. These findings on computed tomography and PET scan and the unusually late resolution of the pulmonary lesions after withdrawal of amiodarone treatment posed a challenging diagnostic problem.
authors.affiliation: Department of Internal Medicine A, Bnai-Zion Medical Centre and Rappaport Family Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Azzam
authors.forename: N
authors.initials: N
authors.lastname: Tov
authors.forename: N
authors.initials: N
authors.lastname: Elias
authors.forename: J E
authors.initials: JE
authors.lastname: Naschitz
mesh_terms: D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D003074:Solitary Pulmonary Nodule / Q000139:chemically induced*; D017180:Tachycardia, Ventricular / Q000188:drug therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone