The effect of supplemental oxygen on postoperative nausea and vomiting in children undergoing dental work.
Administration of 80% intraoperative oxygen has been proposed as being a cheap, safe and effective means of reducing postoperative nausea and vomiting (PONV) but no studies have been performed in the high risk paediatric population. We tested whether 80% intraoperative oxygen reduces PONV in well children undergoing elective day-stay dental treatment under general anaesthesia. Ninety-five children received standardized sevoflurane, morphine, vecuronium anaesthesia with either 30% or 80% intraoperative oxygen and no antiemetic prophylaxis in a randomized, double blind, prospective trial. There was no difference in PONV or in the use of rescue ondansetron between the groups. The total incidence of PONV was 40% in the group that received 30% oxygen and 33% in those that received 80% oxygen. High inspired intraoperative oxygen was not found to significantly reduce PONV in well children undergoing dental work under general anaesthesia.
Donaldson
A B P
AB
Department of Anaesthesia, Royal Brisbane and Women's Hospital, Brisbane, Queensland.
D000293:Adolescent; D000766:Anesthesia, Dental / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D019140:Dental Care for Children; D003814:Dentistry, Operative / Q000379:methods*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D010100:Oxygen / Q000627:therapeutic use*; D010102:Oxygen Inhalation Therapy / Q000379:methods; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control*; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D018570:Risk Assessment; D016896:Treatment Outcome
D010100:Oxygen