title: Predicting changes in blood flow in patient-specific operative plans for treating aortoiliac occlusive disease.
abstract: Traditionally, a surgeon will select a procedure for a particular patient on the basis of past experience with patients with a similar state of disease. The experience gained from this patient will be selectively used when treating the next patient with similar symptoms. This article describes a surgical planning system that was developed to enable a vascular surgeon to create and test alternative operative plans prior to surgery for a given patient. One-dimensional and three-dimensional hemodynamic (i.e., blood flow) simulations were performed for rest and exercise for operative plans for two aorto-femoral bypass patients and compared with actual postoperative data. The information obtained from one-dimensional (volume flow distribution and pressure losses) and three-dimensional (flow, pressure, and wall shear stress) hemodynamic simulations may be clinically relevant to vascular surgeons planning interventions.
authors.affiliation: Department of Surgery, Stanford University, Stanford, California 94305-5431, USA. nwilson@stanford.edu
authors.forename: Nathan M
authors.initials: NM
authors.lastname: Wilson
authors.forename: Frank R
authors.initials: FR
authors.lastname: Arko
authors.forename: Charles A
authors.initials: CA
authors.lastname: Taylor
mesh_terms: D001018:Aortic Diseases / Q000503:physiopathology / Q000601:surgery*; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D001783:Blood Flow Velocity / Q000502:physiology; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D007083:Iliac Artery; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D010347:Patient Care Planning; D012984:Software; D025321:Surgery, Computer-Assisted / Q000379:methods*