title: Biomarkers in croakers Micropogonias furnieri (Teleostei: Sciaenidae) from polluted and non-polluted areas from the Patos Lagoon estuary (Southern Brazil): evidences of genotoxic and immunological effects.
abstract: Biomarkers of exposure and effect of pollutants were analyzed in croakers Micropogonias furnieri (Teleostei: Sciaenidae) captured in winter and summer in a polluted and in a non-polluted site at the Patos Lagoon estuary (Southern Brazil). Catalase and glutathione S-transferase activities (exposure biomarkers) and lipid peroxidation (effect biomarker) were analyzed in liver samples. Other two effect biomarkers were also studied: blood cells DNA damage (through comet assay and micronucleus test) and respiratory burst measurements. In a broad view, results point to an important seasonal variation of the biochemical biomarkers analyzed. However, data obtained clearly indicate that croakers collected in winter at the polluted site were subjected to a level of clastogenic agents sufficient to generate irreversible genetic damages (mutations) and impair the fish immune system.
authors.affiliation: Programa de Pós-Graduação em Oceanografia Biológica, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil.
authors.forename: Lílian Lund
authors.initials: LL
authors.lastname: Amado
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: da Rosa
authors.forename: Alice Meirelles
authors.initials: AM
authors.lastname: Leite
authors.forename: Loraine
authors.initials: L
authors.lastname: Moraes
authors.forename: Wagner Vaz
authors.initials: WV
authors.lastname: Pires
authors.forename: Grasiela L Leães
authors.initials: GL
authors.lastname: Pinho
authors.forename: Camila Martinez Gaspar
authors.initials: CM
authors.lastname: Martins
authors.forename: Ricardo Berteaux
authors.initials: RB
authors.lastname: Robaldo
authors.forename: Luis Eduardo Maia
authors.initials: LE
authors.lastname: Nery
authors.forename: José Maria
authors.initials: JM
authors.lastname: Monserrat
authors.forename: Adalto
authors.initials: A
authors.lastname: Bianchini
authors.forename: Pablo Elias
authors.initials: PE
authors.lastname: Martinez
authors.forename: Laura Alicia
authors.initials: LA
authors.lastname: Geracitano
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D001773:Blood Cells / Q000187:drug effects; D001938:Brazil; D002374:Catalase / Q000187:drug effects / Q000378:metabolism; D004249:DNA Damage / Q000187:drug effects / Q000502:physiology*; D004781:Environmental Exposure; D004784:Environmental Monitoring; D005393:Fish Diseases / Q000139:chemically induced; D005982:Glutathione Transferase / Q000187:drug effects / Q000378:metabolism; D007154:Immune System Diseases / Q000139:chemically induced / Q000662:veterinary; D015227:Lipid Peroxidation / Q000187:drug effects; D008668:Metallothionein / Q000032:analysis; D010473:Perciformes / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D016897:Respiratory Burst / Q000187:drug effects; D012621:Seasons; D012623:Seawater / Q000737:chemistry; D014876:Water Pollution / Q000009:adverse effects*
chemical_list: D015415:Biomarkers; D008668:Metallothionein; D002374:Catalase; D005982:Glutathione Transferase