Identification of atractyloside by LC-ESI-MS in alleged herbal poisonings.
An LC-MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera.
Steenkamp
P A
PA
Biosciences, CSIR, Private Bag X 2, Modderfontein 1645, South Africa. psteenkamp@csir.co.za
Harding
N M
NM
van Heerden
F R
FR
van Wyk
B-E
BE
D001278:Atractyloside / Q000032:analysis* / Q000506:poisoning*; D001826:Body Fluids / Q000737:chemistry; D036084:Callilepis / Q000737:chemistry / Q000506:poisoning; D002853:Chromatography, Liquid; D049429:Forensic Pathology; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry / Q000506:poisoning; D010939:Plant Poisoning / Q000175:diagnosis* / Q000473:pathology; D018517:Plant Roots / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D014781:Viscera / Q000737:chemistry*
D010936:Plant Extracts; D001278:Atractyloside