Regional differences in the epidemiology of invasive pneumococcal disease in toddlers in Germany.
In a population-based study, regional differences in incidence, serotype distribution and resistance rates in invasive pneumococcal disease in 1-2-year-old children were related to different day care attendance rates. Day-care attendance appears to be a relevant risk factor in some German states and should be considered for inclusion in the recommendations for pneumococcal vaccination of children at risk.
Siedler
Anette
A
Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany. siedlera@rki.de
Reinert
Ralf René
RR
Toschke
Michael
M
Al-Lahham
Adnan
A
von Kries
Rüdiger
R
D000293:Adolescent; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002656:Child Day Care Centers; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D011159:Population Surveillance; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects
D000900:Anti-Bacterial Agents; D004917:Erythromycin