title: Autoinducer 2 affects biofilm formation by Bacillus cereus.
abstract: Cell-free supernatants from growing Bacillus cereus strain ATCC 10987 induced luminescence in a Photorhabdus luminescens DeltaluxS mutant, indicating the production of functional autoinducer 2 (AI-2). The exogenous addition of in vitro synthesized AI-2 had an inhibitory effect on biofilm formation by B. cereus and promoted release of the cells from a preformed biofilm.
authors.affiliation: Microbiologie et Génétique Moléculaire, INRA (UMR1238), CNRS (UMR2585), INAPG, F-78850 Thiverval-Grignon, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Auger
authors.forename: Evelyne
authors.initials: E
authors.lastname: Krin
authors.forename: Stéphane
authors.initials: S
authors.lastname: Aymerich
authors.forename: Michel
authors.initials: M
authors.lastname: Gohar
mesh_terms: D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development*; D003470:Culture Media; D015964:Gene Expression Regulation, Bacterial; D006714:Homoserine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007783:Lactones / Q000378:metabolism* / Q000494:pharmacology*; D015398:Signal Transduction
chemical_list: D003470:Culture Media; D007783:Lactones; C091088:N-octanoylhomoserine lactone; D006714:Homoserine