title: Biological activity and composition of the essential oils of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica.
abstract: The essential oils obtained by water distillation from aerial parts of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica were analyzed by gas chromatography and gas chromatography/mass spectrometry. 1,8-Cineole (32.5 and 26.1%, respectively) was the main component in both oils. The oil of A. aleppica subsp. aleppica was also found to be rich in bisabolol and its derivates. When tested for their antimicrobial, antiinflammatory, and antinociceptive activities, the oil of A. aleppica subsp. aleppica showed significant antiinflammatory, antinociceptive, and moderate antimicrobial activities.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470, Eskisehir, Turkey. giscan@anadolu.edu.tr
authors.forename: Gökalp
authors.initials: G
authors.lastname: Işcan
authors.forename: Neşe
authors.initials: N
authors.lastname: Kirimer
authors.forename: Mine
authors.initials: M
authors.lastname: Kürkçüoglu
authors.forename: Turan
authors.initials: T
authors.lastname: Arabaci
authors.forename: Esra
authors.initials: E
authors.lastname: Küpeli
authors.forename: K Hüsnü Can
authors.initials: KH
authors.lastname: Başer
mesh_terms: D031162:Achillea / Q000737:chemistry*; D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D003511:Cyclohexanols / Q000032:analysis; D000077591:Eucalyptol; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male; D051379:Mice; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D003511:Cyclohexanols; D039821:Monoterpenes; D009822:Oils, Volatile; D000077591:Eucalyptol