title: Sirt1: a metabolic master switch that modulates lifespan.
authors.forename: Ingo B
authors.initials: IB
authors.lastname: Leibiger
authors.forename: Per-Olof
authors.initials: PO
authors.lastname: Berggren
mesh_terms: D000375:Aging; D000818:Animals; D031204:Caloric Restriction; D005947:Glucose / Q000378:metabolism*; D022781:Hepatocytes / Q000378:metabolism*; D006655:Histone Deacetylases / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008099:Liver / Q000378:metabolism*; D051379:Mice; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D056564:Sirtuin 1; D037761:Sirtuins / Q000378:metabolism / Q000502:physiology*; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D014157:Transcription Factors; C447939:SIRT1 protein, human; D056564:Sirtuin 1; D037761:Sirtuins; D006655:Histone Deacetylases; D005947:Glucose