title: Preliminary report: Correct diagnosis of sex in fetal cells isolated from cervical mucus during early pregnancy.
abstract: The aim of this study was to determine the accuracy of sexing fetal cells isolated from cervical mucus. Immunopositive cells identified using a fetal-specific antibody were isolated and subjected to genetic analysis. Fetal sex was predicted in all 22 samples, as confirmed by analysis of the corresponding placental tissue. This study validates the accuracy of our test for sex diagnosis and confirms the ability to effectively recover and analyse fetal cells from the cervical mucus during early pregnancy.
authors.affiliation: Monash IVF, Clayton, Victoria, Australia. dmantzaris@monashivf.edu.au
authors.forename: Debbie
authors.initials: D
authors.lastname: Mantzaris
authors.forename: David
authors.initials: D
authors.lastname: Cram
authors.forename: Christine
authors.initials: C
authors.lastname: Healy
authors.forename: Donna
authors.initials: D
authors.lastname: Howlett
authors.forename: Gab
authors.initials: G
authors.lastname: Kovacs
mesh_terms: D000328:Adult; D002582:Cervix Mucus / Q000166:cytology*; D005260:Female; D005333:Fetus / Q000166:cytology*; D005865:Gestational Age; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D016133:Polymerase Chain Reaction / Q000379:methods; D011247:Pregnancy; D012307:Risk Factors; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012732:Sex Determination Analysis / Q000379:methods*