Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats.
Ethanolic extract of Beta vulgaris roots given orally at doses of 1000, 2000 and 4000 mg/kg exhibited significant dose-dependent hepatoprotective activity against carbontetrachloride (CCl(4))-induced hepatotoxicity in rats. Hepatotoxicity and its prevention were assessed by serum markers viz. cholesterol, triglyceride, alanine amino transferase and alkaline phosphatase.
Agarwal
M
M
Department of Pharmacology, VMMC and Safdarjung Hospital, New Delhi, India. monika_anuj@yahoo.com
Srivastava
V K
VK
Saxena
K K
KK
Kumar
A
A
D000469:Alkaline Phosphatase / Q000097:blood / Q000187:drug effects; D000818:Animals; D027461:Beta vulgaris / Q000737:chemistry*; D002251:Carbon Tetrachloride / Q000008:administration & dosage / Q000494:pharmacology; D056486:Chemical and Drug Induced Liver Injury; D002784:Cholesterol / Q000097:blood; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000737:chemistry; D005260:Female; D008099:Liver / Q000293:injuries; D008107:Liver Diseases / Q000517:prevention & control*; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012838:Silymarin / Q000494:pharmacology; D014280:Triglycerides / Q000097:blood
D010936:Plant Extracts; D012838:Silymarin; D014280:Triglycerides; D000431:Ethanol; D002784:Cholesterol; D002251:Carbon Tetrachloride; D000469:Alkaline Phosphatase