Remodeling characteristics of minimally diseased coronary arteries are consistent along the length of the artery.
Using a method that creates anatomically correct, 3-dimensional arterial reconstructions, 55 minimally diseased coronary arteries from 40 patients were studied. Homogenous remodeling characteristics along the entire length of the artery were observed in 48 arteries (87%). In the aggregate, arteries exhibited compensatory expansive remodeling. Individually, the full spectrum of compensatory expansive remodeling (60%), excessive expansive remodeling (21%), and constrictive remodeling (19%) was observed across arteries. Each artery was consistent in its remodeling characteristics from proximal to distal portions of the artery, and the remodeling pattern of each artery was independent within the same patient.
Feldman
Charles L
CL
Cardiovascular Division, Brigham & Women's Hospital, Boston, Massachusetts, USA.
Coskun
Ahmet Umit
AU
Yeghiazarians
Yerem
Y
Kinlay
Scott
S
Wahle
Andreas
A
Olszewski
Mark E
ME
Rossen
James D
JD
Sonka
Milan
M
Popma
Jeffrey J
JJ
Orav
John
J
Kuntz
Richard E
RE
Stone
Peter H
PH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000473:pathology*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography