Human protein reference database--2006 update.
Human Protein Reference Database (HPRD) (http://www.hprd.org) was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein-protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein-protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (http://www.genprot.org), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data.
Mishra
Gopa R
GR
Institute of Bioinformatics, International Tech Park, Bangalore 560 066, India.
Suresh
M
M
Kumaran
K
K
Kannabiran
N
N
Suresh
Shubha
S
Bala
P
P
Shivakumar
K
K
Anuradha
N
N
Reddy
Raghunath
R
Raghavan
T Madhan
TM
Menon
Shalini
S
Hanumanthu
G
G
Gupta
Malvika
M
Upendran
Sapna
S
Gupta
Shweta
S
Mahesh
M
M
Jacob
Bincy
B
Mathew
Pinky
P
Chatterjee
Pritam
P
Arun
K S
KS
Sharma
Salil
S
Chandrika
K N
KN
Deshpande
Nandan
N
Palvankar
Kshitish
K
Raghavnath
R
R
Krishnakanth
R
R
Karathia
Hiren
H
Rekha
B
B
Nayak
Rashmi
R
Vishnupriya
G
G
Kumar
H G Mohan
HG
Nagini
M
M
Kumar
G S Sameer
GS
Jose
Rojan
R
Deepthi
P
P
Mohan
S Sujatha
SS
Gandhi
T K B
TK
Harsha
H C
HC
Deshpande
Krishna S
KS
Sarker
Malabika
M
Prasad
T S Keshava
TS
Pandey
Akhilesh
A
D030562:Databases, Protein / Q000706:statistics & numerical data; D023281:Genomics; D006801:Humans; D020407:Internet; D025941:Protein Interaction Mapping; D020033:Protein Isoforms / Q000032:analysis / Q000235:genetics / Q000502:physiology; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000032:analysis / Q000235:genetics / Q000502:physiology; D020543:Proteome / Q000737:chemistry / Q000235:genetics* / Q000502:physiology*; D040901:Proteomics; D015398:Signal Transduction; D018511:Systems Integration; D014584:User-Computer Interface
D020033:Protein Isoforms; D011506:Proteins; D020543:Proteome