title: Reactivation of koi herpesvirus infections in common carp Cyprinus carpio.
abstract: Two co-habitation studies with common carp were conducted to determine whether latent infections of koi herpesvirus (KHV) exist. Fish were exposed to KHV using 2 different temperature profiles, which induced low and high initial mortality. Subsequently, certain groups of fish were co-habited with naive fish while others were not. Koi herpesvirus was reactivated in fish from 3 of the 5 experimental tanks. Reactivation of the virus occurred regardless of the initial mortality associated with the virus or whether fish were co-habited with naive fish. The reactivation of the virus in our experiments occurred several months after the initial exposure to KHV and appeared to be temperature dependent.
authors.affiliation: CEFAS Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset DT4 8UB, UK. sthisoph@isu.edu
authors.forename: S
authors.initials: S
authors.lastname: St-Hilaire
authors.forename: N
authors.initials: N
authors.lastname: Beevers
authors.forename: K
authors.initials: K
authors.lastname: Way
authors.forename: R M
authors.initials: RM
authors.lastname: Le Deuff
authors.forename: P
authors.initials: P
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: Joiner
mesh_terms: D000818:Animals; D002347:Carps; D004797:Enzyme-Linked Immunosorbent Assay; D005393:Fish Diseases / Q000635:transmission* / Q000821:virology*; D006564:Herpesviridae / Q000235:genetics*; D006566:Herpesviridae Infections / Q000635:transmission / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011156:Population Density; D013696:Temperature; D013997:Time Factors