[HIV infection and the kidneys (Part II): Morphologic changes and their diagnostic significance].
HIV-infected patients may be faced with a variety of renal problem patterns. HIV-associated nephropathy is a unique pattern of sclerosing glomerulopathy and represents the most rapidly progressive form of focal segmental glomerulosclerosis. This study involved the examination of 32 renal biopsies: by light, immunofluorescence, and electron microscopy, in order to determine the most accurate and reliable diagnostic procedure. The findings show that the most sensitive and accurate procedure is electron microscopy, capable of detecting specific EM changes very early on, which is sufficient for the diagnosis of HIV-associated nephropathy.
Basta-Jovanović
Gordana
G
Institute of Pathology, School of Medicine, University of Belgrade.
Radojević
Sanja
S
Savin
Marina
M
Terzić
Tatjana
T
Nenadović
Maja
M
Stojimirović
Biljana
B
Skodrić
Stevo
S
Nesić
Vidosava
V
Dikman
Steve
S
D016263:AIDS-Associated Nephropathy / Q000175:diagnosis / Q000473:pathology*; D001706:Biopsy; D005923:Glomerulosclerosis, Focal Segmental / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology*