WormBase: better software, richer content.
WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.
Schwarz
Erich M
EM
Division of Biology, 156-29 California Institute of Technology, Pasadena, CA, 91125, USA. emsch@its.caltech.edu
Antoshechkin
Igor
I
Bastiani
Carol
C
Bieri
Tamberlyn
T
Blasiar
Darin
D
Canaran
Payan
P
Chan
Juancarlos
J
Chen
Nansheng
N
Chen
Wen J
WJ
Davis
Paul
P
Fiedler
Tristan J
TJ
Girard
Lisa
L
Harris
Todd W
TW
Kenny
Eimear E
EE
Kishore
Ranjana
R
Lawson
Dan
D
Lee
Raymond
R
Müller
Hans-Michael
HM
Nakamura
Cecilia
C
Ozersky
Phil
P
Petcherski
Andrei
A
Rogers
Anthony
A
Spooner
Will
W
Tuli
Mary Ann
MA
Van Auken
Kimberly
K
Wang
Daniel
D
Durbin
Richard
R
Spieth
John
J
Stein
Lincoln D
LD
Sternberg
Paul W
PW
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry* / Q000235:genetics*; D018076:DNA, Complementary / Q000737:chemistry; D030541:Databases, Genetic; D020224:Expressed Sequence Tags / Q000737:chemistry; D049751:Genome, Helminth; D023281:Genomics; D020407:Internet; D020641:Polymorphism, Single Nucleotide; D034622:RNA Interference; D012984:Software; D014584:User-Computer Interface
D029742:Caenorhabditis elegans Proteins; D018076:DNA, Complementary