[Morphological study of placenta and liver of pregnant rats in experimental endotoxicosis and after ceolite protection].
In 45 rats and 120 fetuses the protective effect of food, containing the additives of natural ceolites, on the outcome of pregnancy complicated by an acute experimental endotoxicosis, caused by hyperthermic challenge of the animals, was studied. Using gravimetric, histological, histochemical, electron microscopical methods and monitoring the markers of endogenous intoxication, it was demonstrated that the consumption of ceolite additives contributed to the increase of resistance of the organism to the extremal challenge. Ceolite enteroprotection of acute endotoxicosis, caused by hyperthermic challenge of the pregnant rats, resulted in the increased survival of animals, lower embryonic losses, adaptive changes in placenta and maternal liver.
Popp
E A
EA
Pravotorov
G V
GV
Novikov
V D
VD
Sklianov
Iu I
IuI
D000818:Animals; D016061:Enterosorption; D005260:Female; D006979:Hyperthermia, Induced; D008099:Liver / Q000648:ultrastructure*; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000648:ultrastructure*; D011225:Pre-Eclampsia / Q000473:pathology / Q000517:prevention & control*; D011247:Pregnancy; D051381:Rats; D017641:Zeolites / Q000627:therapeutic use*
D017641:Zeolites