title: Abdominal positron-emission tomography lesions with increased standardized uptake values correlate with intraoperative findings.
abstract: BACKGROUND
  The reporting of standardized uptake value (SUV) on fluoro-2-deoxy-D-glucose positron-emission tomography (FDG-PET) in colorectal cancer is becoming common practice, but its clinical utility remains to be determined. This study was designed to compare FDG-PET uptake as measured by SUV with operative findings.
  
  
  METHODS
  A colorectal cancer database was queried to identify patients who underwent FDG-PET scans with reported SUVs followed by exploratory laparotomy within 3 months and compare these results to determine FDG-PET sensitivity.
  
  
  RESULTS
  Of 46 patients, 16 (34.8%) were found to be have increased extent of disease intraoperatively than seen on FDG-PET scan. This patient population had a statistically significant decreased mean maximal SUV than the patients whose FDG-PET scan equaled intraoperative findings (P < .025).
  
  
  CONCLUSIONS
  This initial study indicates patients with potentially resectable disease by PET scan but decreased FDG uptake should undergo laparoscopic evaluation before performing laparotomy.
authors.affiliation: Division of Internal Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: Sara
authors.initials: S
authors.lastname: Horst
authors.forename: Ergun
authors.initials: E
authors.lastname: Kocak
authors.forename: Donn
authors.initials: D
authors.lastname: Young
authors.forename: Joseph
authors.initials: J
authors.lastname: Mantil
authors.forename: Edward W
authors.initials: EW
authors.lastname: Martin
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging / Q000601:surgery; D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18