A successful anticoagulation protocol for the first HeartMate II implantation in the United States.
Bleeding and thrombus formation are common problems with life-threatening implications in patients receiving a left ventricular assist device. We describe the anticoagulation protocol for the 1st patient in the United States to undergo successful implantation of the HeartMate II left ventricular assist system.
Amir
Offer
O
Department of Cardiopulmonary Transplantation, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
Bracey
Arthur W
AW
Smart
Frank W
FW
Delgado
Reynolds M
RM
Shah
Nyma
N
Kar
Biswajit
B
D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D000991:Antithrombins / Q000008:administration & dosage / Q000627:therapeutic use; D003911:Dextrans / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006353:Heart-Assist Devices; D006629:Hirudins / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010446:Peptide Fragments / Q000008:administration & dosage / Q000627:therapeutic use; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000379:methods*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D012770:Shock, Cardiogenic / Q000628:therapy*; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control*
D000925:Anticoagulants; D000991:Antithrombins; D003911:Dextrans; D006629:Hirudins; D010446:Peptide Fragments; D011994:Recombinant Proteins; C074619:bivalirudin