Pyogenic liver abscess: a retrospective analysis of 107 patients during a 3-year period.
Pyogenic liver abscess (PLA) is a potentially life-threatening disease, and early diagnosis may be difficult. In order to provide diagnostic clues and to enhance the prompt management of such cases, we retrospectively investigated the clinical characteristics of PLA during a 3-year period in a tertiary-care hospital. The crude incidence rate of PLA in our study was 446.1 per 100,000 hospital admissions. Male predominance and a mean age of 57.6 +/- 14.4 years were observed. Diabetes mellitus was the most common concomitant disease, and biliary pathologies were the most common predisposing cause of this type of abscess. The most common clinical features were fever, chills, and abdominal pain. Leukocytosis was found in 67.3% of the patients, and the observed C-reactive protein (CRP) values were high. The most common pathogen was Klebsiella pneumoniae. The mortality rate was 6.5%. A complete history, physical examination, evaluation of the white blood cell count and CRP, and the prompt arrangement of imaging studies may lead to an earlier diagnosis. The aggressive performance of image-guided catheter drainage and the appropriate administration of antibiotics may reduce the mortality rate of PLA.
Chan
Khee-Siang
KS
Department of Intensive Care Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Chen
Chin-Ming
CM
Cheng
Kuo-Chen
KC
Hou
Ching-Cheng
CC
Lin
Hung-Jung
HJ
Yu
Wen-Liang
WL
D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D046290:Liver Abscess, Pyogenic / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017678:Sex Distribution; D013997:Time Factors