title: [US-guided percutaneous management of femoral artery pseudoaneurysms by thrombin injection: personal experience and review of the literature].
abstract: Treatment of femoral artery pseudoaneurysms includes US-guided compression, endovascular coil embolisation or stenting, thrombin injection and open surgical repair. Thrombin injection is currently the standard approach to all non-complicated pseudoaneurysms of the peripheral arteries. Between January 2001 and December 2004, 59 pseudoaneurysms of the femoral artery were submitted to percutaneous US-guided thrombin injection in our surgery division. Complicated pseudoaneurysms, patients in whom percutaneous treatment failed, and chronic pseudoaneurysms with large necks were excluded from this kind of treatment and underwent surgical repair. Eighteen patients were on therapeutic anticoagulation (30.5%) and none of the pseudoaneurysms had an associated arteriovenous fistula. All patients were submitted to clinical and ultrasound follow-up at 24 hours and at 1, 6 and 12 months, and thereafter at yearly intervals for evaluation of recurrences. The thrombin injection was successful in 57/59 patients (96.6%) while two patients (3.4%) were submitted to surgical treatment after failure of the procedure. In 1 patient (1.7%) an additional injection was necessary to achieve complete thrombosis of the pseudoaneurysm. No complications occurred; none of the patients reported discomfort and there was no request for sedation. No recurrences were seen at follow-up. Nowadays US-guided percutaneous thrombin injection is the treatment of choice for femoral artery pseudoaneurysms. Surgical treatment is reserved to rare selected cases. More studies are necessary to evaluate further indications for treatment of visceral or small distal artery pseudoaneurysms.
authors.affiliation: I Divisione Clinicizzata di Chirurgia Generale, Università degli Studi di Verona, Ospedale Civile Maggiore, Verona.
authors.forename: Gian Franco
authors.initials: GF
authors.lastname: Veraldi
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Tasselli
authors.forename: Maria
authors.initials: M
authors.lastname: Firpo
authors.forename: Corrado
authors.initials: C
authors.lastname: Pedrazzani
authors.forename: Andrea
authors.initials: A
authors.lastname: Ruzzenente
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000601:surgery*; D002406:Catheterization, Peripheral; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D005500:Follow-Up Studies; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D018084:Ultrasonography, Interventional
chemical_list: D006490:Hemostatics; D013917:Thrombin