Acquired haemophilia heralded by bleeding into the oral mucosa in a patient with bullous pemphigoid, rheumatoid arthritis, and vitiligo.
Acquired haemophilia is rare and potentially fatal, with a mortality of 20% if left untreated. There is a strong association with other autoimmune diseases. This report describes a patient with rheumatoid arthritis, vitiligo, and bullous pemphigoid where the diagnosis of acquired haemophilia was made after an extensive bleed into a bullous lesion in the buccal mucosa. This case highlights some of the potential complications of acquired haemophilia and its treatment.
Patel
R S
RS
Department of Haemostasis and Thrombosis, Directorate of Haematology, Leicester Royal Infirmary, Leicester LE1 5WW, UK. rakeshspatel@hotmail.com
Harman
K E
KE
Nichols
C
C
Burd
R M
RM
Pavord
S
S
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D006467:Hemophilia A / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D009061:Mouth Mucosa; D006472:Oral Hemorrhage / Q000209:etiology*; D010391:Pemphigoid, Bullous / Q000150:complications*; D014820:Vitiligo / Q000150:complications*