Unnatural selection: reducing antibiotic resistance in neonatal units.
Antibiotic use selects for antibiotic resistant bacteria. This is an example of rapid Darwinian natural selection in action. It occurs in neonatal intensive care units with the use of parenteral antibiotics, and in the community with oral antibiotic use. A 10 point plan is put forward to reduce antibiotic resistance in neonatal units.
Isaacs
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Department of Allergy, Immunology & Infectious Diseases, Children's Hospital at Westmead, Westmead, Sydney, 2122, NSW, Australia. davidi@chw.edu.au
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003428:Cross Infection / Q000517:prevention & control; D003906:Developing Countries; D024881:Drug Resistance, Bacterial; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000592:standards*; D012641:Selection, Genetic; D018805:Sepsis / Q000175:diagnosis
D000900:Anti-Bacterial Agents