An unusual presentation of rhinofacial zygomycosis due to Cunninghamella sp. in an immunocompetent patient: a case report and literature review.
Zygomycosis is a rare fungal infection usually found in immunocompromised patients. It is a rapidly progressing infection with a high mortality rate. Our report describes an unusual case of rhinofacial zygomycosis due to Cunninghamella sp. in an immunocompetent patient, who presented with a slowly progressive swelling of the left cheek. An interrupted course of amphotericin B treatment caused regression of the lesion. Drug therapy was abandoned due to impairment of renal function. The patient was clinically and radiologically disease free for 2 years following cessation of therapy.
Jayasuriya
N S S
NS
Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka.
Tilakaratne
W M
WM
Amaratunga
E A P D
EA
Ekanayake
M K B
MK
D058186:Acute Kidney Injury / Q000139:chemically induced; D000328:Adult; D000666:Amphotericin B / Q000009:adverse effects / Q000627:therapeutic use; D000935:Antifungal Agents / Q000009:adverse effects / Q000627:therapeutic use; D020093:Cunninghamella / Q000472:pathogenicity*; D006801:Humans; D025301:Hyphae; D007121:Immunocompetence; D008297:Male; D008443:Maxillary Sinus / Q000382:microbiology; D009091:Mucormycosis / Q000188:drug therapy / Q000382:microbiology*; D010254:Paranasal Sinus Diseases / Q000188:drug therapy / Q000382:microbiology*; D013172:Spores, Fungal
D000935:Antifungal Agents; D000666:Amphotericin B