Perioperative management of oral anticoagulation.
Based on an individual assessment of risk factors for arterial or venous thrombosis and the risk of postoperative bleeding, this article outlines the preoperative and postoperative approach to anticoagulant management. Preceding this is a brief description of the therapies most commonly used in the perioperative period. The prevention of arterial thromboembolism is considered separately from the prevention of venous thrombosis.
O'Donnell
Martin
M
McMaster University and Henderson Research Centre, Hamilton, ON L8V 1C3, Canada.
Kearon
Clive
C
D000284:Administration, Oral; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D019990:Perioperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000188:drug therapy / Q000517:prevention & control*; D011379:Prognosis; D012307:Risk Factors; D013514:Surgical Procedures, Operative / Q000009:adverse effects* / Q000379:methods; D015996:Survival Rate; D013923:Thromboembolism / Q000188:drug therapy / Q000517:prevention & control*; D016896:Treatment Outcome
D000925:Anticoagulants