title: Biological studies of indigenous medicinal plants--I: physicochemical and antimicrobial screening of non-alkaloidal constituents of some solanaceous seeds.
abstract: The seeds of Atropa belladonna Datura fastuosa D. stramoniurn and Hyoscyamus niger were investigated for the isolation and anti-microbial activity of non-alkaloidal constituents. The compounds were separated by column chromatography and spectral studies i.e. IR and UV were performed to ascertain their chemical nature. The anti-microbial activity of crude extracts and purified compounds was tested against Gram positive and Gram negative bacteria and a fungus. All the micro-organisms tested were markedly inhibited, however, the crude extracts as well as the purified compounds isolated from the seeds of A. belladonna and D. fastuosa showed little inhibitory activity.
authors.affiliation: Department of Pharmacy, University of the Punjab, Allama Iqbal Campus, Lahore-54000, Pakistan.
authors.forename: F Z
authors.initials: FZ
authors.lastname: Khan
authors.forename: M
authors.initials: M
authors.lastname: Alam
authors.forename: R
authors.initials: R
authors.lastname: Saleem
authors.forename: I
authors.initials: I
authors.lastname: Rashid