Fanconi anemia manifesting as a squamous cell carcinoma of the hard palate: a case report.
Fanconi anemia is a rare autosomal recessive disorder characterized by various congenital malformations, progressive bone marrow failure at a very young age and of solid tumors development. The authors present a rare case of a squamous cell carcinoma of the hard palate in a Fanconi Anaemia patient. The atypical clinical manifestation rendered the diagnosis more difficult. This case, for age of appearance, sex and localization, is unique in international literature. We recommend a quarterly follow up of the oral-rhino-pharynx complex in FA patients and to consider as carcinomas, all oral lesions that last more than two weeks.
Gasparini
Giulio
G
U,O, Maxillofacial Surgery, Catholic University Medical School, Rome, Italy. giuliogasparini@yahoo.it
Longobardi
Gianluigi
G
Boniello
Roberto
R
Di Petrillo
Alessandro
A
Pelo
Sandro
S
D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005199:Fanconi Anemia / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019647:Oral Surgical Procedures / Q000379:methods; D010157:Palatal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D021362:Palate, Hard; D014057:Tomography, X-Ray Computed