title: Single molecule fluorescence control for nanotechnology.
abstract: Nanoscience and nanotechnology are providing fresh approaches to engineer materials with practical applications such as molecular-sized therapeutic and diagnostic devices, drug delivery vehicles, environmental sensors, high-rate manufacturing platforms, and self-assembling nanomachines. In many cases, researchers are mimicking biological systems that easily achieve molecular scale control through directed self-assembly. In parallel, a revolution has occurred in the basic sciences, which utilizes recent advances in fluorescence microscopy to achieve single molecule detection capability. The future will see a merger of these two separate research thrusts, as single molecule detection will afford optimal control over the assembly and performance of individual nanoscale devices.
authors.affiliation: Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, Michigan 48109-1055, USA.
authors.forename: David
authors.initials: D
authors.lastname: Rueda
authors.forename: Nils G
authors.initials: NG
authors.lastname: Walter
mesh_terms: D005453:Fluorescence; D008856:Microscopy, Fluorescence; D036103:Nanotechnology; D009696:Nucleic Acids / Q000737:chemistry
chemical_list: D009696:Nucleic Acids