Risk factors for groin wound infection after femoral artery catheterization: a case-control study.
OBJECTIVE
Groin wound infection (GWI) after femoral artery catheterization is unusual. However, several reports of GWI associated with the use of a Perclose device appear in the surgical literature.


METHODS
A case-control study.


METHODS
We pooled 23 cases and 83 controls from a university hospital and a community medical center.


METHODS
A case was defined as a patient who developed a GWI after a femoral artery catheterization. At the university hospital, 3 controls were randomly selected from the at-risk population and matched to each case by time of procedure only (within 2 weeks). At the community medical center, 4 controls were selected and matched to each case by time of procedure (within 2 weeks), sex, and age (within 5 years).


RESULTS
We considered several covariates, including age, sex, body mass index, medical conditions, Perclose use, hematoma formation, and antithrombotic therapy. In a multivariate model, only hematoma formation (odds ratio, 68.8; 95% confidence interval, 12.1-391.4) and glycoprotein IIb/IIIa platelet inhibitor therapy (odds ratio, 6.1; 95% confidence interval, 1.1-33.6) were statistically significant predictors of GWI; Perclose use (odds ratio, 0.9; 95% confidence interval, 0.2-3.7) was not a statistically significant predictor of GWI. However, most of the hematomas (15/17) formed after procedures during which a Perclose device was used.


CONCLUSIONS
Perclose use did not have any additional effect on GWI risk beyond the effect that hematoma formation had.
Polgreen
Philip M
PM
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA. philip-polgreen@uiowa.edu
Diekema
Daniel J
DJ
Vandeberg
Jeff
J
Wiblin
R Todd
RT
Chen
Yi Yi
YY
David
Sherry
S
Rasmus
Dianne
D
Gerdts
Nicole
N
Ross
Angelena
A
Katz
Louis
L
Herwaldt
Loreen A
LA
D016022:Case-Control Studies; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000295:instrumentation; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005263:Femoral Artery; D006119:Groin; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology