Adverse reactions associated with dapsone therapy in HIV-positive patients: a case presentation and review.
Dapsone is commonly used for the prophylaxis of Pneumocystis jiroveci pneumonia in patients with a diagnosis of HIV infection who have allergies to sulfa-based drugs. Dapsone has several adverse effects in its profile that make it a potentially dangerous second-line agent. We report an adverse effect encountered in an HIV-positive patient receiving dapsone and review the common adverse effects encountered with this alternative treatment option.
Stroup
Jeffrey S
JS
University of Oklahoma College of Pharmacy, Tulsa, USA.
Stephens
Johnny R
JR
Reust
Randall
R
Miller
J Angela
JA
D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control*; D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003622:Dapsone / Q000009:adverse effects* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000503:physiopathology*; D006801:Humans; D008297:Male; D045363:Pneumocystis carinii / Q000472:pathogenicity*; D011020:Pneumonia, Pneumocystis / Q000209:etiology / Q000517:prevention & control*
D000890:Anti-Infective Agents; D003622:Dapsone