title: [Hydration of patients treated with cisplatin: practical investigation and establishment of a protocol].
abstract: BACKGROUND
  Administration of cisplatin requires hyperhydration of the patient to prevent nephrotoxic effects of this molecule.
  
  
  METHODS
  A survey done in different hospitals - university hospitals, general hospitals and cancer institutes--has shown a large variability in the hydration protocols. A multidisciplinary group was set up in our university hospital comprising oncologists, nephrologists and pharmacists. This group has developed a consensual local protocol from a bibliographic analysis (Medline) and from the personal experience of each member.
  
  
  CONCLUSIONS
  This protocol was approved by our hospital's Committee of Drugs and Medical Devices.
authors.affiliation: Pharmacie Centrale, CHU de Caen, Caen, France. guillaume.saint-lorant@wanadoo.fr
authors.forename: Guillaume
authors.initials: G
authors.lastname: Saint-Lorant
authors.forename: Jeannick
authors.initials: J
authors.lastname: Madelaine
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Galais
authors.forename: Lobbedez
authors.initials: L
authors.lastname: Thierry
authors.forename: Valérie
authors.initials: V
authors.lastname: Chédru-Legros
mesh_terms: D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D012996:Solutions
chemical_list: D012996:Solutions; D002945:Cisplatin