title: Solid-phase approach to tetrahydroquinolones using a sulfur linker cleaved by SmI2.
abstract: [reaction: see text] A sulfur alpha-heteroatom-substituted carbonyl (HASC) linker has been utilized in a solid-phase approach to tetrahydroquinolones. The route illustrates the compatibility of the linker system with palladium-catalyzed transformations and its utility for library synthesis. The linker is cleaved by electron transfer from samarium(II) iodide.
authors.affiliation: The School of Chemistry, University of Manchester, UK.
authors.forename: Kristy L
authors.initials: KL
authors.lastname: Turner
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Baker
authors.forename: Saidul
authors.initials: S
authors.lastname: Islam
authors.forename: David J
authors.initials: DJ
authors.lastname: Procter
authors.forename: Mark
authors.initials: M
authors.lastname: Stefaniak