title: Photodynamic therapy for subfoveal classic choroidal neovascularization related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like).
abstract: OBJECTIVE
  To evaluate the safety and efficacy of photodynamic therapy with verteporfin (PDT) for subfoveal classic choroidal neovascularization (CNV) related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like).
  
  
  METHODS
  Retrospective review of 16 eyes from 14 patients with subfoveal classic CNV associated with PIC or POHS-like and treated with PDT.
  
  
  RESULTS
  The mean visual acuity increased from 4.5/10 (range: 1/10-9/10) to 7/10 (range: 2/10-10/10) after a mean follow-up of 21 months (range: 8-32 months) and a mean number of 2 PDT (range: 1-6). Visual acuity remained stable or improved in 13 of the 16 eyes (81%) and decreased in three.
  
  
  CONCLUSIONS
  This nearly two-year follow-up study suggests that PDT could be helpful for patients with subfoveal classic CNV related to PIC or POHS-like.
authors.affiliation: Department of Ophthalmology, Centres Hospitaliers Universitaires Brugmann et Saint-Pierre, ULB, Bruxelles, Belgium. laurence.postelmans@chu-brugmann.be
authors.forename: Laurence
authors.initials: L
authors.lastname: Postelmans
authors.forename: Brigitte
authors.initials: B
authors.lastname: Pasteels
authors.forename: Pascale
authors.initials: P
authors.lastname: Coquelet
authors.forename: Laure
authors.initials: L
authors.lastname: Caspers
authors.forename: Claire
authors.initials: C
authors.lastname: Verougstraete
authors.forename: Anita
authors.initials: A
authors.lastname: Leys
authors.forename: Mieke
authors.initials: M
authors.lastname: Wirix
authors.forename: Martine
authors.initials: M
authors.lastname: Mauget-Faÿsse
authors.forename: Maddalena
authors.initials: M
authors.lastname: Quanranta
authors.forename: Bernadette
authors.initials: B
authors.lastname: Snyers
authors.forename: Erica
authors.initials: E
authors.lastname: Smets
mesh_terms: D000293:Adolescent; D000328:Adult; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000209:etiology; D015821:Eye Infections, Fungal / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005584:Fovea Centralis; D005654:Fundus Oculi; D006660:Histoplasmosis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D012189:Retrospective Studies; D013577:Syndrome; D016896:Treatment Outcome; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin