title: An outbreak of Serratia marcescens bloodstream infections associated with misuse of drug vials in a surgical ward.
abstract: We report an outbreak of Serratia marcescens bloodstream infection due to contamination of total parenteral nutrition solution by insulin or poligeline solution when single-use vials were used for multiple doses in a surgical ward. Four patients had severe sepsis, and no patient died. Multidose vials, used either correctly or incorrectly, may be associated with bloodstream infection.
authors.affiliation: Divisione di Malattie Infettive, Spedali Civili- Universita degli Studi di Brescia, Italy. ange.pan@tiscali.it
authors.forename: Angelo
authors.initials: A
authors.lastname: Pan
authors.forename: Lucia
authors.initials: L
authors.lastname: Dolcetti
authors.forename: Catia
authors.initials: C
authors.lastname: Barosi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Catenazzi
authors.forename: Tomaso
authors.initials: T
authors.lastname: Ceruti
authors.forename: Lucio
authors.initials: L
authors.lastname: Ferrari
authors.forename: Silvia
authors.initials: S
authors.lastname: Magri
authors.forename: Eugenia
authors.initials: E
authors.lastname: Quiros Roldan
authors.forename: Laura
authors.initials: L
authors.lastname: Soavi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Carnevale
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology* / Q000209:etiology; D003428:Cross Infection / Q000453:epidemiology / Q000209:etiology; D004196:Disease Outbreaks; D004340:Drug Contamination; D004349:Drug Packaging; D019983:Guideline Adherence; D006235:Hand Disinfection; D006757:Hospital Units; D006764:Hospitals, Community; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016868:Serratia Infections / Q000453:epidemiology* / Q000209:etiology; D012706:Serratia marcescens