title: Postrenal transplant non-EBV multiple myeloma of donor origin.
abstract: Multiple myeloma occurring after solid organ transplantation is a rare condition, with only a few case reports found in the literature. We report a case of Epstein-Barr virus-negative, posttransplant multiple myeloma in a 67-year-old female, presenting 18 months after renal transplantation. Interestingly, fluorescence in situ hybridization analysis of the tumor revealed a Y chromosome in the majority of the cells, indicating that the neoplasm was derived from the donor kidney. To our knowledge, this represents the first reported case with these features.
authors.affiliation: Department of Radiology, University of Washington Medical Center, Seattle, Washington, USA.
authors.forename: N
authors.initials: N
authors.lastname: Peri
authors.forename: S
authors.initials: S
authors.lastname: Kussick
authors.forename: R
authors.initials: R
authors.lastname: Bakthavatsalam
authors.forename: L
authors.initials: L
authors.lastname: Mitsumori
authors.forename: M
authors.initials: M
authors.lastname: Dighe
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D041322:Chromosomes, Human, Y; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000473:pathology; D009101:Multiple Myeloma / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology; D014019:Tissue Donors