title: Higher preoperative D-dimer value remain high postoperatively in patients with rheumatoid arthritis compared with those with osteoarthrosis.
abstract: The differences in hemostatic condition between patients with inflammatory rheumatoid arthritis (RA) and noninflammatory osteoarthrosis (OA) were studied. Twenty-six patients undergoing total knee arthroplasty were enrolled. Compared with OA patients, RA patients showed a higher platelet count and D-dimer value preoperatively, and D-dimer remained high for 1 week after the operation. Patients with OA showed popular DD change, with the lowest value observed before the operation, and a gradual increase for 1 week after the operation. The highest value of thrombin-antithrombin complex was observed immediately after the operation. Fibrinogen and the clot rate at 1 week after operation were higher in both patient groups. We concluded that patients with RA showed different perioperative hemostatic change than patients with OA.
authors.affiliation: Tokyo Women's Medical University, Medical Center East, 2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Mukubo
authors.forename: Miwako
authors.initials: M
authors.lastname: Kawamata
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000601:surgery; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000097:blood* / Q000601:surgery; D020246:Venous Thrombosis / Q000097:blood
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D