The regulation of endocytosis by kinases: cell biology meets genomics.
The mechanisms of signal transduction and vesicular transport have traditionally been studied in isolation, but recent studies make it clear that the two processes are inextricably linked. A new genome-wide analysis of human kinases using RNA interference shows an unexpected depth and complexity to the interactions between these processes.
Balklava
Zita
Z
Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.
Grant
Barth D
BD
D000818:Animals; D022163:Clathrin-Coated Vesicles / Q000378:metabolism; D004705:Endocytosis / Q000235:genetics* / Q000502:physiology*; D023281:Genomics; D006801:Humans; D008954:Models, Biological; D010770:Phosphotransferases / Q000235:genetics* / Q000378:metabolism*
D010770:Phosphotransferases