title: Quality of life and body image in the assessment of psychological impact of lipodystrophy: validation of the Italian version of assessment of body change and distress questionnaire.
abstract: Lipodystrophy (LD) includes morphologic changes that are distressing to patients with HIV. We tested the validity of an Italian version of the Assessment of Body Change and Distress (ABCD) questionnaire and analysed its relationship to physical and mental aspects of Health-Related Quality of Life. Two hundred and fifty-two patients completed the questionnaires. Construct validity of the ABCD was tested against the MOS-HIV Health Survey, body mass-index (BMI) and CD4+ T-lymphocyte counts. Cronbach's alpha for the ABCD total score was 0.94. The ABCD showed the hypothesized moderate correlations to MOS-HIV scales and clinical variables. Preliminary evidence supports the reliability and validity of the Italian version of the ABCD in people with HIV and LD. This questionnaire may be useful to identify people experiencing greater impact of LD, or to evaluate the impact of interventions to treat LD such as plastic surgery.
authors.affiliation: Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy. g.guaraldi@unimo.it
authors.forename: G
authors.initials: G
authors.lastname: Guaraldi
authors.forename: G
authors.initials: G
authors.lastname: Orlando
authors.forename: R
authors.initials: R
authors.lastname: Murri
authors.forename: M
authors.initials: M
authors.lastname: Vandelli
authors.forename: M
authors.initials: M
authors.lastname: De Paola
authors.forename: B
authors.initials: B
authors.lastname: Beghetto
authors.forename: G
authors.initials: G
authors.lastname: Nardini
authors.forename: S
authors.initials: S
authors.lastname: Ciaffi
authors.forename: F
authors.initials: F
authors.lastname: Vichi
authors.lastname: Esposito
authors.forename: A W
authors.initials: AW
authors.lastname: Wu
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D001828:Body Image; D015992:Body Mass Index; D018791:CD4 Lymphocyte Count; D005260:Female; D039682:HIV-Associated Lipodystrophy Syndrome / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life / Q000523:psychology*; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014177:Translations
chemical_list: D044966:Anti-Retroviral Agents