title: Sexual pleasure in women with obsessive-compulsive disorder?
abstract: BACKGROUND
  Although patients with OCD have reported sexual dissatisfaction frequently, controlled studies are sparse. This study compared subjective appreciation of sexuality and sexual functioning between OCD patients and healthy subjects and controlled for the influence of medication or OCD subtypes on sexual functioning and satisfaction.
  
  
  METHODS
  Self-report questionnaires were sent to 350 female outpatients with OCD and 101 questionnaires were completed.
  
  
  RESULTS
  OCD patients reported significantly more sexual disgust (t = 4.48, p < 0.001), less sexual desire (t = 5.52, p < 0.001), sexual arousal (t = 4.28, p < 0.001), and satisfying orgasms (t = 4.94, p < 0.001), than controls. Neither medication nor OCD phenotypes did affect outcome.
  
  
  CONCLUSIONS
  A self-report questionnaire and relatively low response-rate (29%) could have biased the results and the sample was limited to women so results might not be generalisable to men.
  
  
  CONCLUSIONS
  Female patients with OCD report low sexual pleasure, high sexual disgust and diminished sexual functioning, which are not only attributed to medication or contamination obsessions. In the future, clinicians should explicitly ask for sexual function in the assessment of patients with OCD.
authors.affiliation: The Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht (UMCU), B.01.206, P.O. Box 85500, 3508 GA Utrecht, The Netherlands. N.C.C.vulink@azu.nl
authors.forename: Nienke C C
authors.initials: NC
authors.lastname: Vulink
authors.forename: Damiaan
authors.initials: D
authors.lastname: Denys
authors.forename: Léonie
authors.initials: L
authors.lastname: Bus
authors.forename: Herman G M
authors.initials: HG
authors.lastname: Westenberg
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002997:Clomipramine / Q000009:adverse effects / Q000627:therapeutic use; D003075:Coitus; D004328:Drive; D005260:Female; D006801:Humans; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D010549:Personal Satisfaction; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D020018:Sexual Dysfunctions, Psychological / Q000175:diagnosis* / Q000523:psychology; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents; D002997:Clomipramine; D017367:Selective Serotonin Reuptake Inhibitors