An outbreak of Serratia marcescens bloodstream infections associated with misuse of drug vials in a surgical ward.
We report an outbreak of Serratia marcescens bloodstream infection due to contamination of total parenteral nutrition solution by insulin or poligeline solution when single-use vials were used for multiple doses in a surgical ward. Four patients had severe sepsis, and no patient died. Multidose vials, used either correctly or incorrectly, may be associated with bloodstream infection.
Pan
Angelo
A
Divisione di Malattie Infettive, Spedali Civili- Universita degli Studi di Brescia, Italy. ange.pan@tiscali.it
Dolcetti
Lucia
L
Barosi
Catia
C
Catenazzi
Patrizia
P
Ceruti
Tomaso
T
Ferrari
Lucio
L
Magri
Silvia
S
Quiros Roldan
Eugenia
E
Soavi
Laura
L
Carnevale
Giuseppe
G
D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology* / Q000209:etiology; D003428:Cross Infection / Q000453:epidemiology / Q000209:etiology; D004196:Disease Outbreaks; D004340:Drug Contamination; D004349:Drug Packaging; D019983:Guideline Adherence; D006235:Hand Disinfection; D006757:Hospital Units; D006764:Hospitals, Community; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016868:Serratia Infections / Q000453:epidemiology* / Q000209:etiology; D012706:Serratia marcescens