title: Health-related quality of life and appropriateness of knee or hip joint replacement.
abstract: BACKGROUND
  We studied the association between explicit appropriateness criteria for total hip joint replacement (THR) and total knee replacement (TKR) with changes in health-related quality of life of patients undergoing these procedures.
  
  
  METHODS
  Prospective observational study of 1576 consecutive patients with diagnoses of osteoarthritis on waiting lists to undergo THR or TKR. Explicit appropriateness criteria using the RAND appropriateness method were applied. Patients completed 2 questionnaires that measured health-related quality of life, the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), before the procedure and 6 months afterward.
  
  
  RESULTS
  Patients who were considered appropriate candidates for these procedures had greater improvements than those who were considered inappropriate candidates in all 3 WOMAC domains (pain, functional limitation, and stiffness; THR: 43.0, 40.6, and 40.4 vs 14.7, 19.1, and 15.9; TKR: 34.9, 32.5, and 30.2 vs 23.2, 18.9, and 17.1; P<.001 for all comparisons). Patients who underwent THR and were judged to be appropriate candidates had greater improvements in the physical function, role-physical, bodily pain, and social function domains of the SF-36 than those judged to be inappropriate candidates (34.4, 35.1, 33.1, and 26.6 vs 19.6, 9.2, 5.7, and 7.0; P = .04, P = .03, P < .001, and P < .001, respectively). Appropriate candidates for TKR demonstrated greater improvement in the social function domain of the SF-36 after the procedure than those deemed inappropriate candidates (19.9 vs 7.9; P = .004) but not in the other domains of functional status.
  
  
  CONCLUSIONS
  These results suggest a direct relationship between explicit appropriateness criteria and better health-related quality-of-life outcomes after THR and TKR surgery. Our results support the use of these criteria for clinical guidelines or evaluation purposes.
authors.affiliation: Unidad de Investigación, Hospital de Galdakao, Galdakao, Vizcaya, Spain. jmquinta@hgda.osakidetza.net
authors.forename: José M
authors.initials: JM
authors.lastname: Quintana
authors.forename: Antonio
authors.initials: A
authors.lastname: Escobar
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Arostegui
authors.forename: Amaia
authors.initials: A
authors.lastname: Bilbao
authors.forename: Jesús
authors.initials: J
authors.lastname: Azkarate
authors.forename: J Ignacio
authors.initials: JI
authors.lastname: Goenaga
authors.forename: Juan C
authors.initials: JC
authors.lastname: Arenaza
mesh_terms: D000203:Activities of Daily Living; D000222:Adaptation, Physiological; D000223:Adaptation, Psychological; D000367:Age Factors; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods / Q000523:psychology*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods / Q000523:psychology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015207:Osteoarthritis, Hip / Q000175:diagnosis / Q000601:surgery; D020370:Osteoarthritis, Knee / Q000175:diagnosis / Q000601:surgery; D010147:Pain Measurement; D018579:Patient Selection; D011336:Probability; D011379:Prognosis; D011446:Prospective Studies; D011788:Quality of Life; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D018434:Sickness Impact Profile; D013030:Spain; D011795:Surveys and Questionnaires