title: Capillary electrophoresis at the omics level: towards systems biology.
abstract: Emerging systems biology aims at integrating the enormous amount of existing omics data in order to better understand their functional relationships at a whole systems level. These huge datasets can be obtained through advances in high-throughput, sensitive, precise, and accurate analytical instrumentation and technological innovation. Separation sciences play an important role in revealing biological processes at various omic levels. From the perspective of systems biology, CE is a strong candidate for high-throughput, sensitive data generation which is capable of tackling the challenges in acquiring qualitative and quantitative knowledge through a system-level study. This review focuses on the applicability of CE to systems-based analytical data at the genomic, transcriptomic, proteomic, and metabolomic levels.
authors.affiliation: Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, Cheongryang, Seoul, Korea.
authors.forename: Suresh
authors.initials: S
authors.lastname: Babu C V
authors.forename: Eun Joo
authors.initials: EJ
authors.lastname: Song
authors.forename: Sheikh Md Enayetul
authors.initials: SM
authors.lastname: Babar
authors.forename: Mun Hyung
authors.initials: MH
authors.lastname: Wi
authors.forename: Young Sook
authors.initials: YS
authors.lastname: Yoo
mesh_terms: D000818:Animals; D019075:Electrophoresis, Capillary; D023281:Genomics / Q000379:methods*; D006801:Humans; D010600:Pharmacology / Q000379:methods; D040901:Proteomics / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods