A new approach to the inhibition of metallo-beta-lactamases.
Spencer
James
J
Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK. jim.spencer@bristol.ac.uk
Walsh
Timothy R
TR
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D008670:Metals / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D013379:Substrate Specificity; D015032:Zinc / Q000737:chemistry; D065093:beta-Lactamase Inhibitors
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D008670:Metals; D065093:beta-Lactamase Inhibitors; D015032:Zinc