title: Percutaneous edge-to-edge mitral valve repair: 2-year follow-up in the first human case.
abstract: We report the first-in-human mitral valve repair using percutaneous technology that creates a "surgical-like" edge-to-edge repair. A catheter-delivered clip was introduced transseptally from the femoral vein, advanced through the mitral orifice, retracted to grasp the leaflets, and detached to create a functional double-orifice valve. The patient had an uncomplicated post-procedural course. Echocardiography at 1- and 2-years post procedure showed mild mitral regurgitation and positive ventricular remodeling. The success of this case suggests that percutaneous mitral valve repair may be a feasible therapy for certain patients suffering from mitral regurgitation.
authors.affiliation: Unidad de Cardiologia, Centro Médico de Caracas, Caracas, Venezuela.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Condado
authors.forename: Harry
authors.initials: H
authors.lastname: Acquatella
authors.forename: Leonardo
authors.initials: L
authors.lastname: Rodriguez
authors.forename: Patrick
authors.initials: P
authors.lastname: Whitlow
authors.forename: Manuel
authors.initials: M
authors.lastname: Vélez-Gimo
authors.forename: Frederick G
authors.initials: FG
authors.lastname: St Goar
mesh_terms: D006328:Cardiac Catheterization; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000628:therapy*