title: Chemical biology at the crossroads of molecular structure and mechanism.
abstract: Chemical insight into biological function is the holy grail of structural biology. Small molecules are central players as building blocks, effectors and probes of macromolecular structure and function.
authors.affiliation: Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94705, USA. doudna@berkeley.edu
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Doudna
mesh_terms: D001671:Biochemistry / Q000379:methods*; D018360:Crystallography, X-Ray; D008967:Molecular Biology / Q000379:methods*; D008968:Molecular Conformation; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D012313:RNA