title: Cartilage hair hypoplasia and multiple basal cell carcinomas.
abstract: Cartilage hair hypoplasia (CHH) is an autosomal recessively inherited syndrome characterized by short stature, sparse hair, and immunodeficiency. An increased incidence of malignancy has been reported in this condition, but basal cell carcinoma and CHH has not previously been reported in the dermatology literature. We report the case of a 25-year-old woman with CHH and multiple basal cell carcinomas. A causal relationship is conceivable and, therefore, for patients with CHH, dermatologists should be aware of a possible increased risk of basal cell carcinomas.
authors.affiliation: Department of Dermatology, University of Virginia, Charlottesville, Virginia 22908, USA.
authors.forename: Jodi M
authors.initials: JM
authors.lastname: Eisner
authors.forename: Mark
authors.initials: M
authors.lastname: Russell
mesh_terms: D000328:Adult; D002280:Basal Cell Carcinoma / Q000150:complications*; D005260:Female; D006197:Hair / Q000473:pathology*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D009378:Neoplasms, Multiple Primary / Q000150:complications; D010009:Osteochondrodysplasias / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*