title: Asymptomatic choroidal granulomas in common variable immunodeficiency.
abstract: Common variable immunodeficiency disease represents the most common cause of significant antibody deficiency in adults. It is a heterogeneous group of disorders that can be sporadic or familial with various modes of inheritance with defects in B-cell function, regulatory T-cells and macrophage function all being reported. Herein a case of asymptomatic bilateral choroidal granulomatous disease in a 27-year-old man with common variable immunodeficiency disease is described.
authors.forename: Shaharm
authors.initials: S
authors.lastname: Kashani
authors.forename: Gus
authors.initials: G
authors.lastname: Gazzard
authors.forename: Stephen
authors.initials: S
authors.lastname: Jolles
authors.forename: Genevieve
authors.initials: G
authors.lastname: Larkin
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000188:drug therapy; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000188:drug therapy; D015862:Choroid Diseases / Q000150:complications*; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000150:complications*; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000150:complications / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone