title: Squamous cell carcinoma of the hand masquerading as a cutaneous infection.
abstract: SUMMARY A 33-year-old male concreter presented with a small abscess on his right index finger following an injury at work. Histological examination of the lesion was consistent with chronic inflammation and Staphylococcus aureus, Streptococcus anginosus and Escherichia coli were isolated on cultures. The lesion was treated as a chronic fungal infection with bacterial superinfection. Seventeen months later, a bone scan showed periarticular involvement, and a diagnostic biopsy identified a well-differentiated squamous cell carcinoma. He underwent amputation of his index and middle fingers. After 4 years of follow up, there has been no evidence of recurrence at the primary site, but he has since developed two further primary squamous cell carcinomas. This case emphasizes the importance of considering malignancy when dealing with chronic infections of the hand.
authors.affiliation: St Vincent's Hospital, Darlinghurst, New South Wales, Australia.
authors.forename: Jemima
authors.initials: J
authors.lastname: Fisher
authors.forename: James
authors.initials: J
authors.lastname: Masson
authors.forename: Robert
authors.initials: R
authors.lastname: Rosen
mesh_terms: D000328:Adult; D000671:Amputation, Surgical / Q000379:methods; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000628:therapy; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004926:Escherichia coli / Q000302:isolation & purification; D005385:Fingers / Q000503:physiopathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012720:Severity of Illness Index; D012874:Skin Diseases, Infectious / Q000175:diagnosis* / Q000628:therapy; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy; D016038:Skin Transplantation / Q000379:methods; D013211:Staphylococcus aureus / Q000302:isolation & purification; D034366:Streptococcus anginosus / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents