title: Witzelsucht after right putaminal hemorrhage: a case report.
abstract: Witzelsucht is a tendency to tell inappropriate and poor jokes. It usually occurs after a focal lesion involving orbitofrontal cortical or paramedian thalamic regions, especially on the right side. Here we report a 56-year-old man developing witzelsucht and hypersexuality after a right putaminal hemorrhage. The hematoma extended to the sublenticular part of posterior internal capsule and mesencephalon. The hemorrhage might have disconnected the fibers in the ascending reticular systems, and the fibers between paramedian thalamus and orbitofrontal cortex, and thus could be responsible for the patient's rare clinical manifestations.
authors.affiliation: Department of Neurology, National Cheng Kung University Medical Center, Tainan, Taiwan.
authors.forename: Ying-Chu
authors.initials: YC
authors.lastname: Chen
authors.forename: Chi-Yu
authors.initials: CY
authors.lastname: Tseng
authors.forename: Ming-Chyi
authors.initials: MC
authors.lastname: Pai
mesh_terms: D003071:Cognition; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020146:Putaminal Hemorrhage / Q000473:pathology / Q000523:psychology*; D012725:Sexual Behavior; D014925:Wit and Humor as Topic