title: Granulocyte-macrophage colony-stimulating factor for perianal hidradenitis suppurativa: report of a case.
abstract: Perianal hidradenitis suppurativa is a chronic inflammatory disease associated with significantly high morbidity, which severely affects the quality of life of those patients suffering from it. We describe a 46-year-old patient with extensive, severe gluteal and perianal PHS of 28 years duration. Repeated wide excisions, fistulotomies, treatments with hyperbaric oxygen, and finally a diverting colostomy were unsuccessful. A new form of treatment with repeated perilesional injections of granulocyte-macrophage colony-stimulating factor, in conjunction with surgical procedures, was performed with excellent results.
authors.affiliation: Department of Internal Medicine F, Assaf Harofeh Medical Center, Zerifin, Israel.
authors.forename: Ahuva
authors.initials: A
authors.lastname: Sharon-Guidetti
authors.forename: Yehiel
authors.initials: Y
authors.lastname: Ziv
authors.forename: Esther
authors.initials: E
authors.lastname: Kummer
authors.forename: Robert
authors.initials: R
authors.lastname: Yogev
authors.forename: Ariel
authors.initials: A
authors.lastname: Halevy
mesh_terms: D001003:Anal Canal; D003125:Colostomy; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D017497:Hidradenitis Suppurativa / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007267:Injections; D008297:Male; D008875:Middle Aged; D014945:Wound Healing
chemical_list: D016178:Granulocyte-Macrophage Colony-Stimulating Factor