Factors determining successful outcome following pneumatic balloon dilation in achalasia cardia.
BACKGROUND
Pneumatic balloon dilation is a popular method of treating patients with achalasia cardia. It may be useful to know the factors that predict response to this treatment.


OBJECTIVE
To determine predictors of outcome following pneumatic balloon dilation in patients with achalasia cardia.


METHODS
Records of 62 patients who had undergone pneumatic dilation using Rigiflex balloon dilators (Boston Scientific, Boston, MA, USA) were reviewed. Follow-up data were available for 52 patients. Data from patients with and without improvement in symptoms were compared.


RESULTS
Of the 52 patients (age mean 44 [range 11-68] years; 27 male; median symptom duration 20 [4-90] months], 42 (81%) patients had response in symptoms after balloon dilatation. On univariate analysis, the responders more often had age> 40 years (26/42 [62%] versus 1/10 [10%], p=0.003), and less often had lower esophageal sphincter pressure> 50 mmHg (8/10 [80%] versus 10/42 [24%], p=0.0007) and mid-esophageal body hypocontraction (7/10 [70%] versus 12/24 [29%] p=0.01) than the non-responders. On multivariate analysis only age <or= 40 years (p=0.02) was associated with poor outcome.


CONCLUSIONS
Younger age may predict non-response to balloon dilation using Rigiflex balloon dilators in patients with achalasia cardia.
Mehta
Rajiv
R
Department of Gastroenterology, Amrita Institute of Medical Sciences,Amrita Lane, Elamakkara P O, Cochin 682 026, India. rmgastro@yahoo.com
John
Anil
A
Sadasivan
Shine
S
Mustafa
C P
CP
Nandkumar
R
R
Raj
V V
VV
Balakrishnan
V
V
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002404:Catheterization / Q000379:methods*; D002648:Child; D004931:Esophageal Achalasia / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome