title: Acoustic analysis findings in objective laryngopharyngeal reflux patients.
abstract: OBJECTIVE
  The aim of this study was to identify the effects of objective laryngopharyngeal reflux (LPR) on the acoustic parameters of patients by comparing their voice samples with that of control subjects.
  
  
  METHODS
  Prospective study in two tertiary reference hospitals.
  
  
  METHODS
  48 consecutive patients with symptoms related to LPR and 64 control subjects were included in the study. Suspected LPR patients underwent a 24-hour ambulatory pH monitoring, and 25 (52%) of them were shown to have objective LPR. Acoustical evaluation results of objective LPR patients were compared with that of symptomatic LPR patients and control subjects.
  
  
  RESULTS
  All frequency perturbation values obtained from objective and symptomatic LPR patients were higher than the control subjects (P<0.01). Mean fundamental frequency, amplitude perturbation measures, and noise-to-harmonics ratio were not significantly different between groups.
  
  
  CONCLUSIONS
  LPR patients have significantly different frequency perturbation values than control subjects.
authors.affiliation: SB Ankara Training and Research Hospital, 2nd Clinic of Otolaryngology, Ankara, Turkey. drhoguz@hmail.com
authors.forename: Haldun
authors.initials: H
authors.lastname: Oguz
authors.forename: Erkan
authors.initials: E
authors.lastname: Tarhan
authors.forename: Murat
authors.initials: M
authors.lastname: Korkmaz
authors.forename: Ugur
authors.initials: U
authors.lastname: Yilmaz
authors.forename: Mustafa A
authors.initials: MA
authors.lastname: Safak
authors.forename: Munir
authors.initials: M
authors.lastname: Demirci
authors.forename: Levent N
authors.initials: LN
authors.lastname: Ozluoglu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007013:Hypopharynx / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D013061:Speech Acoustics; D014832:Voice Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014833:Voice Quality