title: Does a first trimester dating scan using crown rump length measurement reduce the rate of induction of labour for prolonged pregnancy? An uncompleted randomised controlled trial of 463 women.
abstract: OBJECTIVE
  To evaluate the effect of a first trimester ultrasound dating scan on the rate of induction of labour for prolonged pregnancy.
  
  
  METHODS
  Randomised controlled trial to include 400 women in each arm of the trial.
  
  
  METHODS
  Participating general practices and a district general teaching hospital.
  
  
  METHODS
  Women attending their general practitioner in the first trimester to confirm pregnancy, in whom a first trimester ultrasound scan was not indicated.
  
  
  METHODS
  Women randomised to the study group (scan group) underwent an ultrasound dating scan between 8 and 12 weeks, measuring crown-rump length. The estimated date of delivery (EDD) was changed if there was a discrepancy of more than 5 days from the gestation, calculated from the last menstrual period (LMP). For the remaining women (no-scan group), gestation was determined using the LMP.
  
  
  METHODS
  The rate of induction of labour for prolonged pregnancy.
  
  
  RESULTS
  Due to circumstances beyond the researchers' control, recruitment was abandoned when 463 women had been enrolled. The EDD was adjusted in 13 (5.7%) women in the scan group and in 2 (0.9%) in the no-scan group. There was no difference in the rate of induction for prolonged pregnancy between the scan (19 [8.2%]) and the no-scan (17 [7.4%]) groups (relative risk 1.10; 95% CI 0.59-2.07).
  
  
  CONCLUSIONS
  Acknowledging the reduced numbers recruited for study, it is concluded that there is no evidence that a first trimester ultrasound dating scan reduces the rate of induction of labour for prolonged pregnancy and may result in a more expensive healthcare strategy.
authors.affiliation: Department of Obstetrics and Gynaecology, The Women's Centre, John Radcliffe Hospital, Oxford, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Harrington
authors.forename: I Z
authors.initials: IZ
authors.lastname: MacKenzie
authors.forename: K
authors.initials: K
authors.lastname: Thompson
authors.forename: M
authors.initials: M
authors.lastname: Fleminger
authors.forename: C
authors.initials: C
authors.lastname: Greenwood
mesh_terms: D000328:Adult; D017046:Cost Savings; D018568:Crown-Rump Length; D005260:Female; D005865:Gestational Age; D006801:Humans; D007751:Labor, Induced / Q000191:economics; D011247:Pregnancy; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D011273:Pregnancy, Prolonged / Q000000981:diagnostic imaging / Q000191:economics / Q000517:prevention & control*; D016216:Ultrasonography, Prenatal / Q000191:economics / Q000379:methods