title: Comparison of unilateral and bilateral transfer of injected oocytes into fallopian tubes: a prospective, randomized clinical trial.
abstract: OBJECTIVE
  To assess whether pregnancy rate differs in unilateral vs. bilateral transfer in "immediate transfer of injected oocytes into the fallopian tubes."
  
  
  METHODS
  Prospective randomized clinical trial.
  
  
  METHODS
  Tertiary university hospital.
  
  
  METHODS
  The study population included 160 patients presenting with male factor infertility who fulfilled the criteria for immediate transfer of injected oocytes into tubes.
  
  
  METHODS
  Four injected oocytes were transferred into two tubes (study group) or one tube (control group).
  
  
  METHODS
  Implantation rate, clinical pregnancy rate, multiple pregnancy rate, and incidence of pregnancy with unknown location (PUL).
  
  
  RESULTS
  A total of 72 (45%) pregnancies were achieved. There were 32 pregnancies (1 PUL, 4 multiple, and 27 singletons) in the bilateral transfer group and 40 pregnancies in the unilateral transfer group (1 PUL, 7 multiple, and 32 singletons). No significant difference was found in the implantation rate, clinical pregnancy rate, multiple pregnancy rate, and incidence of PUL.
  
  
  CONCLUSIONS
  This study demonstrates that no difference in outcome occurred between unilateral and bilateral transfer in microinjected oocytes intrafallopian transfer (MIFT). Therefore, along with the same outcome parameters, unilateral transfer is the preferred method of MIFT.
authors.affiliation: Dr. Shariati Hospital, Department of Obstetrics and Gynecology, Vali-e-asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Alleyassin
authors.forename: Afsaneh
authors.initials: A
authors.lastname: Khademi
authors.forename: Marzieh
authors.initials: M
authors.lastname: Aghahosseini
authors.forename: Leili
authors.initials: L
authors.lastname: Safdarian
authors.forename: Hojatollah Saeidi
authors.initials: HS
authors.lastname: Saeidabadi
authors.forename: Hylda
authors.initials: H
authors.lastname: Hedayati
mesh_terms: D000293:Adolescent; D000328:Adult; D005187:Fallopian Tubes; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000379:methods*; D006801:Humans; D008845:Microinjections; D009865:Oocytes / Q000166:cytology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data; D011446:Prospective Studies; D020554:Sperm Injections, Intracytoplasmic