title: Biomimetic surface modifications based on the cyanobacterial iron chelator anachelin.
abstract: Siderophores are natural iron chelators that have been evolutionarily selected to bind to Fe ions with very high binding constants. We utilize these unique properties to bind to metal oxide surfaces using a fragment of the cyanobacterial siderophore anachelin. The resulting poly(ethylene glycol) conjugate forms stable adlayers on TiO2 as has been shown by variable angle spectroscopic ellipsometry and X-ray photoelectron spectroscopy. Moreover, these coated surfaces are highly protein-resistant against the adsorption of full human serum.
authors.affiliation: Laboratory for Surface Science and Technology, Department of Materials, Surface SolutionS GmbH, Switzerland. stefan.zuercher@mat.ethz.ch
authors.forename: Stefan
authors.initials: S
authors.lastname: Zürcher
authors.forename: David
authors.initials: D
authors.lastname: Wäckerlin
authors.forename: Yann
authors.initials: Y
authors.lastname: Bethuel
authors.forename: Barbora
authors.initials: B
authors.lastname: Malisova
authors.forename: Marcus
authors.initials: M
authors.lastname: Textor
authors.forename: Samuele
authors.initials: S
authors.lastname: Tosatti
authors.forename: Karl
authors.initials: K
authors.lastname: Gademann
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D000458:Cyanobacteria / Q000737:chemistry; D007502:Iron Chelating Agents / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011806:Quinolinium Compounds / Q000737:chemistry*
chemical_list: D007502:Iron Chelating Agents; D009842:Oligopeptides; D011806:Quinolinium Compounds; C420972:anachelin; D011092:Polyethylene Glycols