Potential applications of laser polarised xenon for CBF measurements by NMR.
Laser polarised (hyperpolarised) 129Xe offers a new potential way for assessment of cerebral blood flow (CBF) by nuclear magnetic resonance (NMR). We present the basic physical principles underlying noble gases'laser polarisation. Distinguishing characteristics of 129Xe NMR properties as well as theoretical basis for CBF measurement using laser polarised 129Xe are emphasized. Recent results are briefly presented and potential applications as well as current limitations of 129Xe in CBF studies are discussed.
Choquet
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P
Service de Biophysique et Médecine Nucléaire, CHU Hautepierre, 1 Avenue Molière, 67098 Strasbourg. Philippe.CHOQUET@chru-strasbourg.fr
Constantinesco
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A
D001927:Brain Diseases / Q000175:diagnosis*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D014979:Xenon Isotopes
D014979:Xenon Isotopes