title: Optical coherence tomography speckle reduction by a partially spatially coherent source.
abstract: Speckle in optical coherence tomography (OCT) images originates in the high spatial coherence of incident light that enables interference of light backscattered from spatially heterogenous tissue specimens. We report results of a numerical simulation and an experiment to test speckle reduction using a partially spatially coherent source. A Gaussian-Schell model for a partially spatially coherent source is used in the OCT simulation. For the experiment, such a source was generated by a spatially coherent boardband light source and a multimode fiber. The advantage of using a multimode fiber in combination with a broadband source is the large number of photons per coherence volume. To illustrate speckle reduction with a partially spatially coherent source, we record low-coherence interferograms of a scattering surface using single-mode and multimode source fibers. Interferograms recorded using a single-mode source fiber are indicative of those observed using conventional OCT. Speckle in OCT images recorded using a multimode source fiber is substantially reduced.
authors.affiliation: University of Texas at Austin, College of Engineering, Department of Biomedical Engineering, Austin, Texas 78703, USA. jeehyun@laser.bli.uci.edu
authors.forename: Jeehyun
authors.initials: J
authors.lastname: Kim
authors.forename: Donald T
authors.initials: DT
authors.lastname: Miller
authors.forename: Eunha
authors.initials: E
authors.lastname: Kim
authors.forename: Sanghoon
authors.initials: S
authors.lastname: Oh
authors.forename: Junghwan
authors.initials: J
authors.lastname: Oh
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Milner
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008027:Light; D008954:Models, Biological; D019047:Phantoms, Imaging; D012542:Scattering, Radiation; D041623:Tomography, Optical Coherence / Q000379:methods*