title: Blue-light filtering intraocular lens in patients with diabetes: contrast sensitivity and chromatic discrimination.
abstract: OBJECTIVE
  To evaluate potential changes in contrast sensitivity and color discrimination in diabetic patients who had cataract surgery and implantation of the blue-light filtering AcrySof Natural (SN60AT) intraocular lens (IOL) compared with an ultraviolet-only filtering (AcrySof SA60AT) IOL.
  
  
  METHODS
  Refractive Surgery Unit, Hospital NISA Valencia al Mar, Valencia, Spain.
  
  
  METHODS
  Forty-four eyes of 22 diabetic patients were enrolled in a blue-light filtering fellow-eye control study. Patients received yellow-tinted IOLs (AcrySof Natural) in 1 eye and non-yellow-tinted IOLs (AcrySof SA60AT) in the fellow eye. Three months after surgery, monocular contrast sensitivity function was measured with the CSV 1000-E contrast sensitivity chart at distance and color discrimination was tested with the Farnsworth-Munsell 100-hue test.
  
  
  RESULTS
  Eyes implanted with the blue-light filtering IOLs showed better contrast sensitivity values than fellow eyes implanted with non-yellow-tinted IOLs (P<.05). The blue-light filtering IOL did not modify chromatic discrimination compared with the non-yellow-tinted IOL (P = .62). In the blue-yellow axis discrimination study, the eyes implanted with the AcrySof Natural IOL had statistically significant better color vision (P = .008).
  
  
  CONCLUSIONS
  In diabetic patients, the AcrySof Natural IOL provides better contrast sensitivity than the AcrySof SA60AT. The blue-light filter of the AcrySof Natural IOL did not cause chromatic discrimination defects based on total error scores and improved color vision in the blue-yellow chromatic axis in diabetic patients.
authors.affiliation: Refractive Surgery Unit, Hospital NISA Valencia al Mar, Valencia, Spain. trg1@vodafone.es
authors.forename: Antonio
authors.initials: A
authors.lastname: Rodríguez-Galietero
authors.forename: Robert
authors.initials: R
authors.lastname: Montés-Micó
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Muñoz
authors.forename: Cesar
authors.initials: C
authors.lastname: Albarrán-Diego
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications* / Q000503:physiopathology; D003118:Color Perception / Q000502:physiology*; D015350:Contrast Sensitivity / Q000502:physiology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification; D011474:Prosthesis Design