title: [Therapy for advanced colorectal carcinoma--new developments and standards].
abstract: Colorectal carcinoma is the second common cause of death from cancer. For a long period patients with metastatic disease were considered incurable except for a small subgroup with isolated surgically complete removable lesions in the lungs and the liver. Chemotherapy was a treatment of unproven value, beneficial in very few patients. However, in the last two decades it has become a well-documented survival prolonging treatment, postponing tumor symptoms in the majority of patients, and potentially curing some patients if combined with aggressive surgery.
authors.affiliation: Medizinische Klinik und Poliklinik II, Abteilung Hämatologie, Onkologie, Immunologie, Rheumatologie, Pulmonologie, Südwestdeutsches Tumorzentrum, Universitätsklinikum der Eberhard-Karls-Universität Tübingen. joerg.hartmann@med.uni-tuebingen.de
authors.forename: J T
authors.initials: JT
authors.lastname: Hartmann
authors.forename: L
authors.initials: L
authors.lastname: Kanz
mesh_terms: D000465:Algorithms; D000970:Antineoplastic Agents / Q000627:therapeutic use / Q000633:toxicity; D017024:Chemotherapy, Adjuvant; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D009367:Neoplasm Staging; D010166:Palliative Care; D011013:Pneumonectomy
chemical_list: D000970:Antineoplastic Agents