title: Low prevalence of pertussis among children admitted with respiratory symptoms during respiratory syncytial virus season.
abstract: Pertussis may go unrecognized during respiratory syncytial virus (RSV) epidemics. Nosocomially transmitted pertussis can be severe in infants. Polymerase chain reaction (PCR) screening may identify infants with pertussis on admission, allowing for preemptive isolation. In a random sample, 1 (0.6%) of 166 children admitted to the hospital during RSV season were Bordetella pertussis PCR positive during a nonepidemic period. These data show that screening may not be useful when pertussis prevalence is low.
authors.affiliation: Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. gksiberr@jhmi.edu
authors.forename: George K
authors.initials: GK
authors.lastname: Siberry
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Paquette
authors.forename: Tracy L
authors.initials: TL
authors.lastname: Ross
authors.forename: Trish M
authors.initials: TM
authors.lastname: Perl
authors.forename: Alexandra
authors.initials: A
authors.lastname: Valsamakis
mesh_terms: D015142:Baltimore / Q000453:epidemiology; D001886:Bordetella pertussis / Q000302:isolation & purification*; D015331:Cohort Studies; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008403:Mass Screening; D016133:Polymerase Chain Reaction; D015995:Prevalence; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000453:epidemiology*; D012621:Seasons; D014917:Whooping Cough / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*