title: Glucosinolate metabolism and its control.
abstract: Glucosinolates and their associated degradation products have long been recognized for their distinctive benefits to human nutrition and plant defense. Because most of the structural genes of glucosinolate metabolism have been identified and functionally characterized in Arabidopsis thaliana, current research increasingly focuses on questions related to the regulation of glucosinolate synthesis, distribution and degradation as well as to the feasibility of engineering customized glucosinolate profiles. Here, we highlight recent progress in glucosinolate research, with particular emphasis on the biosynthetic pathway and its metabolic relationships to auxin homeostasis. We further discuss emerging insight into the signaling networks and regulatory proteins that control glucosinolate accumulation during plant development and in response to environmental challenge.
authors.affiliation: Department of Plant Sciences, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
authors.forename: C Douglas
authors.initials: CD
authors.lastname: Grubb
authors.forename: Steffen
authors.initials: S
authors.lastname: Abel
mesh_terms: D017360:Arabidopsis / Q000378:metabolism; D029681:Arabidopsis Proteins; D005961:Glucosinolates / Q000096:biosynthesis / Q000378:metabolism*; D007210:Indoleacetic Acids / Q000378:metabolism; D010940:Plant Proteins; D010944:Plants / Q000378:metabolism*; D020598:Proto-Oncogene Proteins c-myb; D015398:Signal Transduction
chemical_list: C511988:ATR1 protein, Arabidopsis; D029681:Arabidopsis Proteins; C511989:CPC protein, Arabidopsis; D005961:Glucosinolates; D007210:Indoleacetic Acids; D010940:Plant Proteins; D020598:Proto-Oncogene Proteins c-myb