Studies on the mode of action of non-steroid anti-inflammatory drugs.
During the past decade the mode of action of anti-inflammatory drugs has mainly been related to the inhibition of prostaglandin (PGS) synthesis (Vane 1971). In a presentation by Burne (1982) it has been shown that PGS are not the only most important mediators of inflammation, and the inhibition of prostaglandin synthesis alone does not explain all common effects and mode of action of NSAIDs. Hence alternative concepts are presented in this paper, which may be adopted as the mode of action of NSAIDs.
Ahmad
S P
SP
Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
Rasheed
S
S