title: [Tear film profile in patients with active thyroid orbithopathy].
abstract: Dry eye symptoms and tear film profile were examined in 21 patients with Graves' disease complicated by active thyroid orbitopathy (OT). Dry eye symptoms and clinical tests: break-up time (BUT), Schirmer I, fluorescein and lissamine green staining in OT patients, were comparable with control group. Dry eye symptoms were present in 85% of OT patients compared with 30% in control group. BUT (5.84 +/- 3,31sec.) and Schirmer test (11.11 +/- 9,14mm) were significantly lower when compared with control group (11.4 +/- 3,75sec and 20.5 +/- 9,65mm). Lissamin green staining intensity score (3.61 +/- 1,74) as well as positive fluorescein staining in OT patients, were significantly higher when compared with control.
authors.affiliation: Z Zakładu Patofizjologii Katedry Patofizjologii i Endokrynologii Slaskiej Akademii Medycznej w Katowicach.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Nowak
authors.forename: Bogdan
authors.initials: B
authors.lastname: Marek
authors.forename: Beata
authors.initials: B
authors.lastname: Kos-Kudła
authors.forename: Dariusz
authors.initials: D
authors.lastname: Kajdaniuk
authors.forename: Lucyna
authors.initials: L
authors.lastname: Siemińska
mesh_terms: D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D006111:Graves Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D007765:Lacrimal Apparatus / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013666:Tears / Q000502:physiology*; D013961:Thyroid Gland / Q000503:physiopathology*