Remineralization potential of an anticaries/antigingivitis mouthrinse.
OBJECTIVE
To assess the ability of a new formulation (Listerine with 0.022% NaF) to remineralize initially decalcified bovine enamel compared to a positive control, clinically established 0.022% NaF rinse.


METHODS
A cyclic demineralization/remineralization in vitro model was utilized and the level of remineralization was monitored by examining the Knoop microhardness over 6 and 18 D/T/R cycles


RESULTS
(1) both the test formulation and positive control rinses were statistically significantly effective in remineralizing artificial lesions in vitro; and (2) the test formulation performed "at least as good as" the positive control. These results support the concept that the remineralization potential of the fluoride rinse is not adversely affected by the addition of essential oils.
Yu
Duncan
D
Pfizer Inc, Morris Plains, NJ, USA. Duncan.yu@pfizer.com
Sipos
Tibor
T
Wu
Mei-Miau
MM
Naleway
Conrad
C
D000818:Animals; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002417:Cattle; D004338:Drug Combinations; D005891:Gingivitis / Q000188:drug therapy; D006244:Hardness / Q000187:drug effects; D009067:Mouthwashes / Q000627:therapeutic use*; D012459:Salicylates / Q000627:therapeutic use*; D012969:Sodium Fluoride / Q000627:therapeutic use*; D013729:Terpenes / Q000627:therapeutic use*; D014089:Tooth Remineralization / Q000379:methods*
D002327:Cariostatic Agents; D004338:Drug Combinations; D009067:Mouthwashes; D012459:Salicylates; D013729:Terpenes; C057473:Listerine; D012969:Sodium Fluoride