title: The effect of parity on placental weight and birth weight: interaction with placental alkaline phosphatase polymorphism.
abstract: The effect of parity on placental weight and birth weight is examined through a series of birth records from an Indian population in Calcutta. Placental weight and birth weight increase with parity, the maximum increment occurring between parities 1 and 2. This is compatible with a hypothesis of sensitization of the mother to foetal, paternally derived, antigens. The three common placental alkaline phosphatase enzymic genotypes have no effect on determining foetal development.
authors.affiliation: Center for Demographic and Population Genetics, University of Texas, USA.
authors.forename: R
authors.initials: R
authors.lastname: Chakraborty
authors.forename: S R
authors.initials: SR
authors.lastname: Das
authors.forename: M
authors.initials: M
authors.lastname: Roy
authors.forename: B N
authors.initials: BN
authors.lastname: Mukherjee
authors.forename: S K
authors.initials: SK
authors.lastname: Das
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase; D000704:Analysis of Variance; D001724:Birth Weight; D005260:Female; D058851:GPI-Linked Proteins; D005838:Genotype; D006761:Hospitals; D006801:Humans; D007194:India; D007527:Isoenzymes / Q000235:genetics*; D008423:Maternal Age; D009929:Organ Size; D010298:Parity; D010920:Placenta / Q000033:anatomy & histology* / Q000201:enzymology*; D011110:Polymorphism, Genetic; D011247:Pregnancy
chemical_list: D058851:GPI-Linked Proteins; D007527:Isoenzymes; D000469:Alkaline Phosphatase; C019839:alkaline phosphatase, placental