title: Male genital tuberculosis in Siberians.
abstract: To study the epidemiology and the clinical picture of male genital tuberculosis in Siberia, Russia. Five hundred and fourteen patients with genitourinary tuberculosis were enrolled in the study: 414 had kidney tuberculosis only, 100 had genital involvement. The clinical picture and structure of genital tuberculosis were investigated: 42 had tuberculosis of scrotal organs and 58 had tuberculosis of the prostate. Urinary cultures, urinalysis, three-glass test, and investigation of the prostate secretion, Mycobacteria culture, and susceptibility testing were performed in all 514 patients. 33.6% of all patients earlier suffered from pulmonary or extrapulmonary tuberculosis and were successfully cured. In 61.9% nephrotuberculosis was diagnosed alongside with an orchiepididymitis. In 30.9% of patients bilateral epididymorchitis was diagnosed. Mycobacteriuria was present in 38.1%. Scrotal fistula was found in 11.9%. In 66.7% the symptoms appeared acutely. Half of the patients with prostate tuberculosis complained of dysuria, 23 (39.6%) had perineal pain, 34 (58.6%) had flank pain. Leucocytes in urine were present in 49 (84.5%) patients, and in prostatic secretion in 45 (77.6%) patients. Erythrocytes in urine were present in 31 (53.4%) patients, and in prostatic secretions in 17 (29.3%) patients. Male genital tuberculosis has no specific pathognomonic signs. Using a special algorithm for the management of patients with prostatitis or epididymitis is recommended.
authors.affiliation: Novosibirsk Research TB Institute, 107/1 Kubovaya str. ap. 57, 630040 Novosibirsk, Russia. ekaterina_k@online.nsk.su
authors.forename: Ekaterina
authors.initials: E
authors.lastname: Kulchavenya
authors.forename: Victor
authors.initials: V
authors.lastname: Khomyakov
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001707:Biopsy, Needle; D015331:Cohort Studies; D004823:Epididymitis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006306:Health Surveys; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D015995:Prevalence; D011379:Prognosis; D011472:Prostatitis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D018570:Risk Assessment; D012720:Severity of Illness Index; D012800:Siberia / Q000453:epidemiology; D014057:Tomography, X-Ray Computed; D014374:Tuberculin Test; D014389:Tuberculosis, Male Genital / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D014401:Tuberculosis, Urogenital / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000995:Antitubercular Agents