title: Familial parathyroid hyperplasia: is there a place for minimally invasive surgery? Description of the first treated case.
abstract: While the majority of patients affected with sporadic primary hyperparathyroidism (sPHPT) can be selected for minimal access surgery, patients affected with 4-gland hyperplasia still do not represent an indication for it. Minimally invasive video-assisted parathyroidectomy (MIVAP) was introduced in 1996; this technique relies on a single central incision and external retraction and therefore allows a bilateral neck exploration. This was the case of a 27-yr-old female with familial primary hyperparathyroidism (FPHPT). Three enlarged glands were immediately identified in orthotopic positions and the fourth was intrathyroideal. A subtotal parathyroidectomy was then performed, leaving a small fragment of the inferior right gland and completed with the cervical thymectomy by inverting the positions of the camera and the retractor assistants with regard to the positions originally described. Quick intraoperative PTH assay (QPTH) confirmed the surgical cure of the disease.
authors.affiliation: Department of Surgery, University of Pisa, Pisa, Italy. p.miccoli@dc.med.unipi.it
authors.forename: P
authors.initials: P
authors.lastname: Miccoli
authors.forename: M N
authors.initials: MN
authors.lastname: Minuto
authors.forename: F
authors.initials: F
authors.lastname: Cetani
authors.forename: C E
authors.initials: CE
authors.lastname: Ambrosini
authors.forename: P
authors.initials: P
authors.lastname: Berti
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology / Q000601:surgery; D019060:Minimally Invasive Surgical Procedures; D016343:Monitoring, Intraoperative; D010279:Parathyroid Diseases / Q000473:pathology* / Q000601:surgery*; D010280:Parathyroid Glands / Q000473:pathology / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods*; D013965:Thyroidectomy / Q000379:methods; D016896:Treatment Outcome; D020535:Video-Assisted Surgery