title: A ring-closing yne-carbonyl metathesis of ynamides.
abstract: [reaction: see text] An acid-catalyzed ring-closing ynamide-carbonyl metathesis is described here. This hetero RCM methodology is applicable to the construction of carbocycles as well as heterocycles such as chromenes, quinolizidines, indolizidines, and pyrrolizidines.
authors.affiliation: Department of Chemistry, University of Minnesota, Minneapolis, 55455, USA.
authors.forename: Kimberly C M
authors.initials: KC
authors.lastname: Kurtz
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
authors.forename: Yanshi
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011763:Pyrrolizidine Alkaloids / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000577:Amides; D006574:Heterocyclic Compounds, 2-Ring; D011763:Pyrrolizidine Alkaloids