[Haemorrhagic colitis in a young male after the use of amoxicillin].
A 16-year-old boy had rectal blood loss due to haemorrhagic colitis probably resulting from oral and intravenous administration of amoxicillin. He also had haemolytic anaemia and thrombocytopenia, both also most likely resulting from the use of amoxicillin and/or ibuprofen. In the week following the discontinuation of amoxicillin and ibuprofen, the symptoms of bloody diarrhoea disappeared spontaneously and the blood picture became normal. Haemorrhagic colitis is a known side effect of amoxicillin that is rarely seen. Discontinuation of treatment typically results in a quick and uneventful recovery.
van Hensbroek
P Boele
PB
Medisch Centrum Alkmaar, afd. Kindergeneeskunde, Wilhelminalaan 12, 1815 JD Alkmaar.
Hack
W W M
WW
Labadie
J
J
D000293:Adolescent; D000658:Amoxicillin / Q000009:adverse effects*; D000743:Anemia, Hemolytic / Q000139:chemically induced; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000139:chemically induced
D000900:Anti-Bacterial Agents; D000658:Amoxicillin