On the role of alkylcobalamins in the vitamin B12-catalyzed reductive dehalogenation of perchloroethylene and trichloroethylene.
Theoretical studies are presented on the structures and reactivity of chlorinated ethylcobalamins, potential intermediates in the vitamin B12-catalyzed reductive dehalogenation of the environmental pollutants perchloroethylene and trichloroethylene; the results suggest an alternative mechanism of catalysis.
Pratt
Derek A
DA
Department of Chemistry, Queen's University, 90 Bader Crescent, Kingston, Ontario, Canada K7L 3N6. pratt@chem.queensu.ca
van der Donk
Wilfred A
WA