Chemical biology at the crossroads of molecular structure and mechanism.
Chemical insight into biological function is the holy grail of structural biology. Small molecules are central players as building blocks, effectors and probes of macromolecular structure and function.
Doudna
Jennifer A
JA
Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94705, USA. doudna@berkeley.edu
D001671:Biochemistry / Q000379:methods*; D018360:Crystallography, X-Ray; D008967:Molecular Biology / Q000379:methods*; D008968:Molecular Conformation; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D013329:Structure-Activity Relationship
D012313:RNA