[Sensitivity of influenza A/H5 viruses isolated from wild birds on the territory of Russia to arbidol in the cultured MDCK cells].
The effect of the antiviral drug arbidol on the reproduction of avian influenza A/H5 viruses was studied in in vitro experiments. The strains were isolated from the wild birds of Eastern Siberia and they were closely related to the 1997-2000 viruses from South-Eastern Asia. Arbidol was shown to exert a selective inhibiting effect on the reproduction of these viruses in the MDCH cell cultures.
Fediakina
I T
IT
Leneva
I A
IA
Iamnikova
S S
SS
Livov
D K
DK
Glushkov
R G
RG
Shuster
A M
AM
D000818:Animals; D000835:Animals, Wild / Q000821:virology; D000998:Antiviral Agents / Q000494:pharmacology*; D001717:Birds / Q000821:virology; D002460:Cell Line; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D007211:Indoles / Q000494:pharmacology*; D053125:Influenza A Virus, H5N2 Subtype / Q000187:drug effects* / Q000502:physiology; D005585:Influenza in Birds / Q000821:virology; D008826:Microbial Sensitivity Tests; D014779:Virus Replication / Q000187:drug effects; D013440:Sulfides
D000998:Antiviral Agents; D007211:Indoles; C086979:umifenovir; D013440:Sulfides