title: Progressive facilitation of antegrade conduction via an accessory pathway in a patient with Wolff-Parkinson-White syndrome and permanent atrial fibrillation.
abstract: The case of a 64-year-old man with Wolff-Parkinson-White syndrome and permanent atrial fibrillation (AF) is reported. The patient was admitted due to electrocardiographic feature of AF with rapid conduction over the left-sided accessory pathway. Administration of pirmenol effectively suppressed the ventricular response via an accessory pathway. A transesophageal echocardiography detected an uncertain thrombus in the left atrial appendage. During the 33-month follow-up period, the ventricular response via an accessory pathway was progressively facilitated. Radiofrequency catheter ablation using a transseptal approach was performed during AF, resulting in complete elimination of the antegrade accessory pathway conduction.
authors.affiliation: Department of Internal Medicine 1, Oita University, Japan.
authors.forename: Naohiko
authors.initials: N
authors.lastname: Takahashi
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Ooie
authors.forename: Mikiko
authors.initials: M
authors.lastname: Nakagawa
authors.forename: Masahide
authors.initials: M
authors.lastname: Hara
authors.forename: Tetsunori
authors.initials: T
authors.lastname: Saikawa
authors.forename: Hironobu
authors.initials: H
authors.lastname: Yoshimatsu
mesh_terms: D000889:Anti-Arrhythmia Agents; D001281:Atrial Fibrillation / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D002036:Bundle of His / Q000187:drug effects / Q000503:physiopathology* / Q000601:surgery; D017115:Catheter Ablation; D004562:Electrocardiography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications / Q000503:physiopathology* / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D010880:Piperidines; C024318:pirmenol