title: Laser in situ keratomileusis outcomes following radial keratotomy, astigmatic keratotomy, photorefractive keratectomy, and penetrating keratoplasty.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) to enhance refractive status following other corneal surgical procedures.
  
  
  METHODS
  Clinical office-based practice.
  
  
  METHODS
  Seventy-one eyes of 57 patients had LASIK for refractive errors following radial keratotomy (n = 22), astigmatic keratotomy (n = 13), photorefractive keratectomy (n = 18), and penetrating keratoplasty (n = 18). A Moria LSK-1 microkeratome was used with a Visx S2 or Wavelight Allegretto excimer laser. Data were acquired by retrospective chart review of all appropriately qualified patients.
  
  
  RESULTS
  The mean preoperative manifest refractive spherical equivalent (MRSE) was -3.93 diopters (D) +/- 2.83 (SD) in myopic eyes and +1.43 +/- 1.79 D in hyperopic eyes. The mean time from the initial corneal surgical procedure to LASIK was 65.0 months. The mean post-LASIK follow-up was 9.40 months (range 1 to 42 months). Postoperatively, the mean MRSE was -0.85 +/- 1.42 D in myopic eyes (P<.0001) and -0.16 +/- 1.09 D in hyperopic eyes (P<.0001). Enhancement by LASIK was required in 14% of eyes.
  
  
  CONCLUSIONS
  In eyes that have had a variety of previous corneal surgeries, LASIK offers a safe and predictable method for enhancing refractive results.
authors.affiliation: Duke University Eye Center, Duke University Medical Center, Durham, North Carolina 27705, USA. afsha003@mc.duke.edu
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Afshari
authors.forename: Frank
authors.initials: F
authors.lastname: Schirra
authors.forename: Peter A
authors.initials: PA
authors.lastname: Rapoza
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Talamo
authors.forename: Klaus
authors.initials: K
authors.lastname: Ludwig
authors.forename: Ron A
authors.initials: RA
authors.lastname: Adelman
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Kenyon
mesh_terms: D001251:Astigmatism / Q000601:surgery*; D003316:Corneal Diseases / Q000601:surgery; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D007646:Keratotomy, Radial / Q000009:adverse effects*; D054018:Lasers, Excimer; D018903:Photorefractive Keratectomy / Q000009:adverse effects*; D012030:Refractive Errors / Q000209:etiology; D054140:Refractive Surgical Procedures; D012086:Reoperation; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity