Surgical therapy for hepatolithiasis: a Western experience.
BACKGROUND
Hepatolithiasis is very common in East Asia but infrequent in Western countries, and few reports have been published in European series. In East Asia, the association between cholangiocarcinoma and hepatolithiasis is well recognized, but, on the contrary, hepatolithiasis is uncommon in Europe and the United States, and the relationship with cholangiocarcinoma is not well established. The goal of this study was to analyze the perioperative and longterm results of surgical therapy for hepatolithiasis.


METHODS
Record review of 22 patients was done to locate immediate (operative morbidity and mortality) and longterm (stone recurrence and survival) results of patients with hepatolithiasis who underwent surgical treatment.


RESULTS
There were 19 (86.4%) hepatic resections and 10 (45.5%) hepatico-jejuno-anastomoses. Operative mortality was absent and morbidity rate was 27.3%. Right hepatectomy was predictive of postoperative complications at multivariate analysis (p = 0.04). One (4.5%) patient had an unknown associated cholangiocarcinoma at time of surgical intervention. Mean followup was 67.59 +/- 65.67 (range 12 to 215) months. None presented recurrent cholangitis during the followup period.


CONCLUSIONS
Surgical therapy is a safe and effective management for hepatolithiasis. The possibility of developing cholangiocarcinoma in inveterate hepatolithiasis is real, and hepatic resection removes this risk.
Vetrone
Gaetano
G
Department of Liver and Multiorgan Transplantation, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Ercolani
Giorgio
G
Grazi
Gian Luca
GL
Ramacciato
Giovanni
G
Ravaioli
Matteo
M
Cescon
Matteo
M
Varotti
Giovanni
G
Del Gaudio
Massimo
M
Quintini
Cristiano
C
Pinna
Antonio Daniele
AD
D000368:Aged; D002137:Calculi / Q000453:epidemiology / Q000601:surgery*; D002763:Cholecystectomy; D015897:Comorbidity; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies