title: [Clinical study of percutaneous ultrasound-guided or freehand core needle biopsy of primary breast cancer].
abstract: OBJECTIVE
  To evaluate ultrasound-guided or freehand percutaneous core needle biopsy in histopathological assessment of primary breast cancer lesions and its utility in primary breast cancer treatment.
  
  
  METHODS
  Retrospectively analysis of the clinical data of 697 primary breast cancer examined by mean of core needle biopsy.
  
  
  RESULTS
  The diagnostic accuracy, false negative rate and insufficiency rate was 90.5%, 8.9% and 0.6%, respectively. Diagnostic accuracy was significantly higher in ultrasound guiding comparing to palpable guiding (92.7% vs. 88.2%, P < 0.05). There was a nonsignificant trend toward increased false negative rate in palpable guiding (10.9% vs. 7.1%, P > 0.05).
  
  
  CONCLUSIONS
  Percutaneous core needle biopsy is reliable in histopathological assessment of primary breast cancer lesions. Ultrasound guiding was superior to palpable guiding in term of diagnostic accuracy in this study.
authors.affiliation: Breast Cancer Unit, Beijing Oncology Hospital, School of Oncology, Peking University, Beijing 100036, China. ouyanghongtao@263.net
authors.forename: Tao
authors.initials: T
authors.lastname: Ouyang
authors.forename: Jin-feng
authors.initials: JF
authors.lastname: Li
authors.forename: Tian-feng
authors.initials: TF
authors.lastname: Wang
authors.forename: Yun-tao
authors.initials: YT
authors.lastname: Xie
authors.forename: Zhao-qing
authors.initials: ZQ
authors.lastname: Fan
authors.forename: Ben-yao
authors.initials: BY
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary