[Clinical study of percutaneous ultrasound-guided or freehand core needle biopsy of primary breast cancer].
OBJECTIVE
To evaluate ultrasound-guided or freehand percutaneous core needle biopsy in histopathological assessment of primary breast cancer lesions and its utility in primary breast cancer treatment.


METHODS
Retrospectively analysis of the clinical data of 697 primary breast cancer examined by mean of core needle biopsy.


RESULTS
The diagnostic accuracy, false negative rate and insufficiency rate was 90.5%, 8.9% and 0.6%, respectively. Diagnostic accuracy was significantly higher in ultrasound guiding comparing to palpable guiding (92.7% vs. 88.2%, P < 0.05). There was a nonsignificant trend toward increased false negative rate in palpable guiding (10.9% vs. 7.1%, P > 0.05).


CONCLUSIONS
Percutaneous core needle biopsy is reliable in histopathological assessment of primary breast cancer lesions. Ultrasound guiding was superior to palpable guiding in term of diagnostic accuracy in this study.
Ouyang
Tao
T
Breast Cancer Unit, Beijing Oncology Hospital, School of Oncology, Peking University, Beijing 100036, China. ouyanghongtao@263.net
Li
Jin-feng
JF
Wang
Tian-feng
TF
Xie
Yun-tao
YT
Fan
Zhao-qing
ZQ
Lin
Ben-yao
BY
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary