Kikuchi-Fujimoto disease: a rare but important cause of fever and lymphadenopathy in pregnant women.
We report a case of Kikuchi-Fujimoto disease (KFD) in a 28-year-old pregnant woman with prolonged fever and generalized lymphadenopathy. We evaluated the patient for etiology of the fever and adenopathy, which were unresponsive to antibiotic therapy. Cervical lymph node histology showed KFD. Currently, there is scant data available regarding the course and treatment of KFD during pregnancy. We administered steroid therapy (prednisone 1 mg/kg/day) to control severe systemic and constitutional symptoms. We observed a reduction in lymph node size as well as abatement of fever and other constitutional symptoms. The patient carried the fetus to full term with no apparent adverse effect. Our experience showed that steroid therapy may be used effectively to control KFD-related symptoms after the first 16 weeks without terminating the pregnancy.
Altuntas
Fevzi
F
Department of Hematology-Oncology, Erciyes University, Faculty of Medicine, Dedeman Oncology Hospital, Kayseri, Turkey. faltuntas@hotmail.com
Sari
Ismail
I
Canoz
Ozlem
O
Yildiz
Orhan
O
Eser
Bulent
B
Cetin
Mustafa
M
Unal
Ali
A
D005260:Female; D005334:Fever / Q000188:drug therapy / Q000209:etiology*; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011256:Pregnancy Outcome; D016896:Treatment Outcome
D011241:Prednisone