title: Can systemic diseases co-induce (not just exacerbate) periodontitis? A hypothetical "two-hit" model.
authors.affiliation: Department of Oral Biology & Pathology, School of Dental Medicine, SUNY at Stony Brook, Stony Brook, NY, USA. lgolub@epo.hsc.sunysb.edu
authors.forename: L M
authors.initials: LM
authors.lastname: Golub
authors.forename: J B
authors.initials: JB
authors.lastname: Payne
authors.forename: R A
authors.initials: RA
authors.lastname: Reinhardt
authors.forename: G
authors.initials: G
authors.lastname: Nieman
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003773:Dental Plaque / Q000150:complications; D004164:Diphosphonates / Q000627:therapeutic use; D006801:Humans; D008954:Models, Biological; D015663:Osteoporosis, Postmenopausal / Q000150:complications; D010518:Periodontitis / Q000188:drug therapy / Q000209:etiology*; D011480:Protease Inhibitors / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D011480:Protease Inhibitors