[The role of mast cells in innate immunity in antibacterial defense].
Nowadays it is well documented that bacteria and/or their products directly or indirectly activate mast cells to secrete mediators and cytokines. These mediators and cytokines induce various effects leading to the development of local inflammation. Moreover, mast cells have the capacity to bind and phagocytose bacteria. What is more, these cells have the capacity to kill bacteria. Thus, mast cells play a pivotal role in host defense, especially in natural immunity, during bacterial infection.
Brzezińska-Błaszczyk
Ewa
E
Zakład Immunologii Doświadczalnej, Uniwersytet Medyczny w Łodzi. ewab@csk.umed.lodz.pl
Rdzany
Rafał S
RS
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology*; D016207:Cytokines / Q000096:biosynthesis; D006801:Humans; D007249:Inflammation / Q000276:immunology; D018836:Inflammation Mediators / Q000276:immunology; D008407:Mast Cells / Q000276:immunology*; D010587:Phagocytosis / Q000276:immunology
D016207:Cytokines; D018836:Inflammation Mediators