title: Hypoprolactinemia following intradermal administration of ouabain in Uromastix hardwickii.
abstract: A variety of drugs can alter the secretion of prolactin (PRL) by the pituitary gland in most animals. Secretion of prolactin is predominantly, under negative control of hypothalamus, and in this respect, it is unique among the pituitary hormones. This study was undertaken to evaluate the crop-sac diameterical response to ouabain treated Uromastix pituitary suspension. 0.1 ml suspension of ouabain treated Uromastix pituitary gave a minimum diametric crop-sac response of 0.85 cm and a maximum of 0.95 cm. Data indicates that oubain promotes the secretion of prolactin inhibiting hormone (PRIH), and produces hypoprolactinemia.
authors.affiliation: Department of Physiology, University of Karachi, Karachi-75270, Pakistan.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Ahmad
authors.forename: Iftikhar
authors.initials: I
authors.lastname: Mahmood
authors.forename: Ruqaiya
authors.initials: R
authors.lastname: Hasan
authors.forename: Habib
authors.initials: H
authors.lastname: Fatima
authors.forename: Aisha
authors.initials: A
authors.lastname: Javaid
authors.forename: Tazeen
authors.initials: T
authors.lastname: Naim
authors.forename: Mansoor
authors.initials: M
authors.lastname: Ahmad