title: RNA helicases: versatile ATP-driven nanomotors.
abstract: RNA helicases are a large family of molecular motors that utilize nucleoside triphosphates to unwind RNA duplexes and to remodel RNA protein complexes. In this review, we discuss the structure and function of RNA helicases with an emphasis on the potential application of these enzymes to control conformational changes in nanoassemblies that contain RNA.
authors.affiliation: Department of Biochemistry and Center for RNA Molecular Biology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
authors.forename: Eckhard
authors.initials: E
authors.lastname: Jankowsky
authors.forename: Margaret E
authors.initials: ME
authors.lastname: Fairman
authors.forename: Quansheng
authors.initials: Q
authors.lastname: Yang
mesh_terms: D000255:Adenosine Triphosphate / Q000502:physiology*; D001709:Biotechnology; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D020365:RNA Helicases / Q000737:chemistry* / Q000502:physiology*; D016601:RNA-Binding Proteins / Q000502:physiology
chemical_list: D016601:RNA-Binding Proteins; D000255:Adenosine Triphosphate; D020365:RNA Helicases