Stability of phosphoinosit1des containing liposomes: effects of triton x-100, temperature and 68 rpm.
The stability of phosphoinositide containing liposomes was investigated. It was found that 2% of triton X-100 completely released entrapped carboxyfluorescein. The release of carboxyfluorescein occurred the most of 58 degrees C (78% at 2 hours) and the least at 4 degrees C (5.4% at 118 hours). When stored at 68 RPM (at 25 degrees C) about the 20% carboxyfluorescein was released at 48 hours, but when the liposomes were kept at 25 degrees C for the same period of time, the release was about 10%.
Riaz
M
M
Faculty of Pharmacy, University of the Punjab, Lahore, Pakistan.
Weiner
N
N