Evaluation of antidiabetic effects of chlorpropamids in the presence of aspirin.
The present work has been done in an attempt to evaluate the hypoglycemic effect of Chlorpropamide in the presence of aspirin. Diabetiogenic effect of Alloxan was utilized which produced an Insulin-Dependent Diabetic State in the animals. Diabetic animals were given oral Chlorpropamide (100 mg/kg body weight) and it was seen that the drug reduced the blood sugar values although not to a significant level. Later the animals were given aspirin (30 mg/kg body weight) alongwith the daily dose of Chlorpropamide and a more significant reduction of blood sugar level took place.
Shafi
A
A
Islamabad Hospital Complex, Islamabad, Pakistan.
Muzaffar
N A
NA