title: Mycobacterium chelonae in a CF patient with anaplastic large cell lymphoma.
abstract: A 13-year-old patient with cystic fibrosis was diagnosed with anaplastic large cell lymphoma. At the same time colonization with Mycobacterium chelonae was detected in sputum cultures. Despite massive immunosuppression, the patient did not show evidence of mycobacterial invasive disease. Colonisation persisted for 18 months after discontinuation of chemotherapy and was not detected in the 6 years thereafter. This case highlights the dilemma of differentiating between colonisation and infection if mycobacteria are found in CF sputum samples.
authors.affiliation: Children's Hospital, University of Duisburg-Essen, Essen, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Tschiedel
authors.forename: H
authors.initials: H
authors.lastname: Grasemann
authors.forename: F
authors.initials: F
authors.lastname: Ratjen
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000175:diagnosis; D016926:Mycobacterium chelonae / Q000302:isolation & purification*; D012137:Respiratory System / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents