New approaches to combating antimicrobial drug resistance.
Recent work shows that the inhibition of the SOS stress response in Escherichia coli reduces the development of resistance to the antibiotics ciprofloxacin and rifampicin. This finding may help in the battle against the rise of resistance to antimicrobial drugs.
Avison
Matthew B
MB
Department of Cellular and Molecular Medicine, Bristol Centre for Antimicrobial Research and Evaluation, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK. Matthewb.Avison@bristol.ac.uk
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000187:drug effects* / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000502:physiology*; D008954:Models, Biological; D009154:Mutation / Q000235:genetics; D013014:SOS Response, Genetics / Q000187:drug effects*
D000900:Anti-Bacterial Agents