Mechanistic studies of an unusual epoxide-forming elimination of a beta-hydroxyalkyl rhodium porphyrin.
A new and remarkably facile sp3-C-O bond forming reaction of beta-hydroxyalkyl Rh porphyrins to form epoxides has been discovered and its mechanism investigated.
Han
Yuan-Zhang
YZ
Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Sanford
Melanie S
MS
England
Michael D
MD
Groves
John T
JT
D000478:Alkylation; D035843:Biomedical Research; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D006878:Hydroxides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D004852:Epoxy Compounds; D006878:Hydroxides; D011166:Porphyrins; D002244:Carbon; D012238:Rhodium; D010100:Oxygen