title: [Auditory brainstem response in severe obstructive sleep apnea-hypopnea syndrome children].
abstract: OBJECTIVE
  To explore the characteristics of auditory brainstem response(ABR) in severe obstructive sleep apnea-hypopnea syndrome.
  
  
  METHODS
  ABR was recorded in 37 severe OSAHS patients (OSAHS group) and 20 controls.
  
  
  RESULTS
  (1) In the OSAHS group, the latency values of waves I, III and V were (1.67+/-0.20) ms, (3.87+/-0.31) ms, (5.70+/-0.31) ms respectively. In the control group, the latency values of waves I, III and V were (1.60+/-0.11) ms, (3.81+/-0.23) ms, (5.61+/-0.23) ms respectively. A statistically significant prolongation was found in the latency values of waves I in OSAHS group compared to control group (P < 0.05). (2) When comparing to the control group, the transmission time between waves III and V was found to be prolonged and waves I and III to be shortened in the OSAHS group. Furthermore, the change was considered statistically significant (P <0.05). (3) A statistically significant elevation was found in response threshold of wave V when comparing to the control group (P < 0.05).
  
  
  CONCLUSIONS
  The pathological sleepiness seen in OSAHS patients may cause ABR abnormalities, as a consequence of the chronic hypoxic and hypercapnic status occurring in the brain-stem and cochlear.
authors.affiliation: Department of Otolaryngology, Pediatric Hospital, Guangzhou, 510120, China. daboliu@126.com.cn
authors.forename: Dabo
authors.initials: D
authors.lastname: Liu
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.forename: Zhenyun
authors.initials: Z
authors.lastname: Huang
authors.forename: Jianwen
authors.initials: J
authors.lastname: Zhong
authors.forename: Lifeng
authors.initials: L
authors.lastname: Zhou
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology*