title: Reservoir competency of goats for the Ap-variant 1 strain of Anaplasma phagocytophilum.
abstract: Field-collected ticks were used to infect goats with either Ap-ha, a strain associated with human disease, or a variant strain, Ap-Variant 1, of Anaplasma phagocytophilum. Goats were shown to be competent as a reservoir for Ap-Variant 1, and challenge and immunosuppression studies were used to further examine infection in the goat model.
authors.affiliation: Centers for Disease Control and Prevention, 1600 Clifton Rd., MS G-13, Atlanta, GA 30333, USA. rfm2@cdc.gov
authors.forename: Robert F
authors.initials: RF
authors.lastname: Massung
authors.forename: Thomas N
authors.initials: TN
authors.lastname: Mather
authors.forename: Michael L
authors.initials: ML
authors.lastname: Levin
mesh_terms: D041081:Anaplasma phagocytophilum / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D000818:Animals; D004195:Disease Models, Animal; D004197:Disease Reservoirs; D016873:Ehrlichiosis / Q000382:microbiology / Q000473:pathology / Q000635:transmission; D005247:Feeding Behavior; D015511:Goat Diseases / Q000382:microbiology / Q000473:pathology; D006041:Goats / Q000382:microbiology*; D006801:Humans; D018884:Ixodes / Q000382:microbiology / Q000502:physiology