title: Assessment of dietary zinc requirement of weaned piglets fed diets with or without microbial phytase.
abstract: Fifty-four pigs, weaned at 26 days of age at an average body weight of 7.74 kg were used in a 26-day experiment to assess the zinc requirement of piglets, using diets based on maize and soybean meal, with or without microbial phytase. The nine experimental diets were the basal diet containing 33 mg of zinc/kg supplemented with 10, 25, 40, 60 or 80 mg of zinc as sulphate (ZnSO(4), 7H(2)O)/kg and the basal diet supplemented with 0, 10, 25 or 40 mg of zinc as sulphate/kg and 700 units (U) of microbial phytase (Natuphos)/kg. Pigs were fed the basal diet for a 7-day adjustment period prior to the 19-day experimental period. Microbial phytase enhanced plasma alkaline phosphatase (AP) activity, plasma zinc and bone zinc concentrations. These parameters increased linearly with zinc intake, with a similar slope with and without phytase. The response of bone zinc-to-zinc added did not plateau. Without microbial phytase, plasma AP activity and zinc concentration were maximized when dietary zinc reached 86 and 92 mg/kg respectively. With microbial phytase they were maximized when dietary zinc concentration reached 54 and 49 mg/kg respectively. Accounting for a safety margin, the recommended supply of zinc for weaned piglets up to 16 kg fed maize-soybean meal diets supplemented with zinc as sulphate is thus of 100-110 mg/kg diet. This supply may be reduced by around 35 mg if the diet is supplemented with 700 U of microbial phytase.
authors.affiliation: Institut National de la Recherche Agronomique, Unité Mixte de Recherches INRA-Agrocampus Rennes Systèmes d'Elevage, Nutrition Animale et Humaine, France.
authors.forename: P S
authors.initials: PS
authors.lastname: Revy
authors.forename: C
authors.initials: C
authors.lastname: Jondreville
authors.forename: J Y
authors.initials: JY
authors.lastname: Dourmad
authors.forename: Y
authors.initials: Y
authors.lastname: Nys
mesh_terms: D010832:6-Phytase / Q000008:administration & dosage* / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000831:Animals, Newborn; D004305:Dose-Response Relationship, Drug; D008297:Male; D009751:Nutritional Requirements; D011897:Random Allocation; D012449:Safety; D013552:Swine / Q000254:growth & development* / Q000378:metabolism; D014886:Weaning; D015430:Weight Gain; D015032:Zinc / Q000008:administration & dosage* / Q000009:adverse effects / Q000097:blood*
chemical_list: D000469:Alkaline Phosphatase; D010832:6-Phytase; D015032:Zinc