title: [Alanine aminotransferase is a substitute marker of viral hepatitis].
abstract: The incidence of viral hepatitis was compared in donors (n = 184532) with the increased or normal activity of alanine aminotransferase (ALT) without the specific markers of hepatitis - HbsAg and anti-HCV. The activity of ALT was found to retain its diagnostic values in preventing blood-transmitted diseases only with the insufficient sensitivity of the specific markers of viral hepatitis in donors. A prospective case-control study of the specific markers of the infections may be recommended to assess the quality of work of diagnostic laboratories.
authors.forename: E B
authors.initials: EB
authors.lastname: Zhiburt
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D001782:Blood Donors; D016022:Case-Control Studies; D006525:Hepatitis, Viral, Human / Q000175:diagnosis*; D006801:Humans
chemical_list: D015415:Biomarkers; D000410:Alanine Transaminase