RNA helicases: versatile ATP-driven nanomotors.
RNA helicases are a large family of molecular motors that utilize nucleoside triphosphates to unwind RNA duplexes and to remodel RNA protein complexes. In this review, we discuss the structure and function of RNA helicases with an emphasis on the potential application of these enzymes to control conformational changes in nanoassemblies that contain RNA.
Jankowsky
Eckhard
E
Department of Biochemistry and Center for RNA Molecular Biology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Fairman
Margaret E
ME
Yang
Quansheng
Q
D000255:Adenosine Triphosphate / Q000502:physiology*; D001709:Biotechnology; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D020365:RNA Helicases / Q000737:chemistry* / Q000502:physiology*; D016601:RNA-Binding Proteins / Q000502:physiology
D016601:RNA-Binding Proteins; D000255:Adenosine Triphosphate; D020365:RNA Helicases