Adalimumab effectively controlled recalcitrant generalized pustular psoriasis in an adolescent.
Generalized pustular psoriasis is a rare form of psoriasis which may be serious and can be fatal. We report here the treatment of an adolescent girl who responded to adalimumab after failing to respond to a combination of methotrexate, cyclosporin and isotretinoin, and having had a pustular reaction that followed the use of etanercept, but might have been triggered by an infection.
Callen
Jeffrey P
JP
Division of Dermatology, University of Louisville, Louisville, KY 40292, USA. jefca@aol.com
Jackson
Joe H
JH
D000068879:Adalimumab; D000293:Adolescent; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D007155:Immunologic Factors; D000068879:Adalimumab