title: [Primary eosinophilic esophagitis].
abstract: Primary eosinophilic esophagitis (EE) is a rare disease with symptoms similar to those of gastroesophageal reflux disease (GERD). However, EE is caused by severe eosinophilic invasion of the esophageal epithelium, typically followed by dysphagia. A man 28 years of age presented persistent symptoms of GERD despite traditional antireflux therapy. Histologic evaluation showed eosinophilia (85 eosinophils/high-power field (x 400)). Treatment by bouginage resulted in mucosal lacerations and transitory clinical improvement. Local steroid therapy for four weeks eliminated the symptoms.
authors.affiliation: H:S Rigshospitalet, Medicinsk Gastroenterologisk Klinik, Abdominalcentret, og Patologiafdelingen, Diagnostisk Center. peppep@sol.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Høyerup
authors.forename: Lars Bo
authors.initials: LB
authors.lastname: Svendsen
authors.forename: Anne Mellon
authors.initials: AM
authors.lastname: Mogensen
authors.forename: Michael
authors.initials: M
authors.lastname: Staun
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000188:drug therapy / Q000473:pathology*; D004941:Esophagitis / Q000188:drug therapy / Q000473:pathology*; D005764:Gastroesophageal Reflux / Q000175:diagnosis; D006801:Humans; D008297:Male