Cutaneous small-vessel vasculitis with unexpected circulating and in situ bound pemphigus autoantibodies.
Pemphigus or pemphigus-related autoantibodies have been found in sera of patients with diverse diseases, such as toxic epidermal necrolysis, thermal burns, and penicillin reactions. Here we report a patient with a typical cutaneous necrotizing vasculitis in whom immunofluorescence studies revealed the presence of circulating and tissue-bound pemphigus autoantibodies.
Pavlović
Milos D
MD
Department of Dermatology, Military Medical Academy, Belgrade, Serbia & Montenegro. mdpavlovic2004@yahoo.com
Zecević
Rados D
RD
D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D010392:Pemphigus / Q000276:immunology*; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D014657:Vasculitis / Q000097:blood* / Q000473:pathology
D001323:Autoantibodies