title: A small scale survey of ivermectin resistance in sheep nematodes using the faecal egg count reduction test on samples collected from Scottish sheep.
abstract: Thirty-eight sheep flocks, predominantly from the south/central Scotland, were examined using a faecal egg count reduction test (FECRT) for the presence of ivermectin (IVM) resistant nematodes. Efficacies of less than 95%, 14-17 days post-treatment, were identified in 6 of 17 naturally grazing flocks where pre-treatment faecal egg counts were in excess of 150 eggs per gram. Efficacies on these IVM resistant farms ranged from 66 to 92%. One other suspected cases of IVM resistance was also identified in returned material. The larvae detected in post-treatment coprocultures from resistant flocks were from the genera Teladorsagia (4 from 6) and Trichostrongylus (2 from 6).
authors.affiliation: Department of Parasitology, Moredun Research Institute, Pentland Science Park, Bush Loan, Penicuik EH26 0PZ, UK. dave.bartley@moredun.ac.uk
authors.forename: D J
authors.initials: DJ
authors.lastname: Bartley
authors.forename: A A
authors.initials: AA
authors.lastname: Donnan
authors.forename: E
authors.initials: E
authors.lastname: Jackson
authors.forename: N
authors.initials: N
authors.lastname: Sargison
authors.forename: G B B
authors.initials: GB
authors.lastname: Mitchell
authors.forename: F
authors.initials: F
authors.lastname: Jackson
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000494:pharmacology*; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D005260:Female; D007559:Ivermectin / Q000494:pharmacology*; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary*; D021261:Parasitic Sensitivity Tests / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology*; D016896:Treatment Outcome
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin