title: Encephalopathy with isolated reversible splenial lesion of the corpus callosum.
abstract: We report a 51-year-old Japanese man with chronic alcoholism who complained of mental confusion following respiratory and intestinal infections. The splenium of the corpus callosum showed hyperintensity on both diffusion-weighted MR images and fluid-attenuated inversion recovery images and hypointensity on T1-weighted images. These findings were resolved on MR images obtained 3 days later. He showed complete neurological recovery within 2 months. We suspected that he had mild encephalopathy with a reversible splenial lesion after systemic viral or bacterial infection.
authors.affiliation: Department of Neurology, Shinoda General Hospital, Yamagata, and the Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Yaguchi
authors.forename: Hisa
authors.initials: H
authors.lastname: Yaguchi
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Itoh
authors.forename: Koichi
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000437:Alcoholism / Q000150:complications; D003337:Corpus Callosum / Q000473:pathology*; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000150:complications / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged