Effects of combined administration of quercetin, rutin, and extract of white radish sprout rich in kaempferol glycosides on the metabolism in rats.
Quercetin, rutin, the extract of white radish sprout rich in kaempferol glycosides, and their combination were intragastrically administered to Wistar rats to investigate the interactive metabolism of these flavonoids. The combined administration of these flavonoids changed the concentrations of the metabolites in plasma as compared with the concentrations after the administration of a single compound.
Hashimoto
Takashi
T
Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University, Japan. takashi@kobe-u.ac.jp
Ueda
Yuko
Y
Oi
Naomi
N
Sakakibara
Hiroyuki
H
Piao
Chengyuan
C
Ashida
Hitoshi
H
Goto
Miho
M
Kanazawa
Kazuki
K
D000818:Animals; D003116:Color; D006027:Glycosides / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000494:pharmacology; D044949:Kaempferols / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism / Q000494:pharmacology*; D018520:Plant Shoots / Q000737:chemistry; D011794:Quercetin / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism / Q000494:pharmacology*; D031224:Raphanus / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D012431:Rutin / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism / Q000494:pharmacology*
D006027:Glycosides; D044949:Kaempferols; D010936:Plant Extracts; D012431:Rutin; D011794:Quercetin