Peripheral T-cell lymphoma.
A 32-year-old man presented with a 5-year history of cutaneous nodules on his head and a diffuse, lichenified eruption. Histopathologic examination showed an atypical lymphocytic infiltrate. Immunophenotyping studies determined that the lymphocyte population to be CD4-positive, with partial loss of CD3 and CD7, and immunogenotyping studies showed a clonal rearrangement of the T-cell receptor. A positron-emission tomography scan showed increased uptake in cervical, axillary, and inguinal lymph nodes. A diagnosis of peripheral T-cell lymphoma was made, and the patient is undergoing chemotherapy.
Rosenberg
Benjamin
B
Departmentof Dermatology, New York University School of Medicine, USA.
D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*