title: Prenatal diagnosis and therapy of upper extremity vascular malformation causing high cardiac output and Kasabach-Merritt sequence: a report of two cases.
abstract: We present two cases of upper extremity vascular malformation causing a high output state in the prenatal period. One fetus responded well to transplacental digitalis treatment. Both newborns had a Kasabach-Meritt sequence including anemia and thrombocytopenia. Postpartum treatment included successful interventional occlusion of the main feeding arteries and subsequent surgical removal of the tumor.
authors.affiliation: Department of Obstetrics and Prenatal Medicine, University of Bonn, Bonn, Germany. daniel.kamil@ukb.uni-bonn.de
authors.forename: D
authors.initials: D
authors.lastname: Kamil
authors.forename: A
authors.initials: A
authors.lastname: Geipel
authors.forename: A
authors.initials: A
authors.lastname: Heep
authors.forename: J
authors.initials: J
authors.lastname: Breuer
authors.forename: G
authors.initials: G
authors.lastname: Knöpfle
authors.forename: U
authors.initials: U
authors.lastname: Gembruch
authors.forename: C
authors.initials: C
authors.lastname: Berg
mesh_terms: D000740:Anemia / Q000209:etiology; D001132:Arm / Q000002:abnormalities* / Q000098:blood supply; D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging* / Q000628:therapy; D021721:Balloon Occlusion / Q000379:methods; D016534:Cardiac Output, High / Q000188:drug therapy / Q000209:etiology*; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004071:Digitalis Glycosides / Q000627:therapeutic use; D005260:Female; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D013921:Thrombocytopenia / Q000209:etiology; D016216:Ultrasonography, Prenatal / Q000379:methods*
chemical_list: D002316:Cardiotonic Agents; D004071:Digitalis Glycosides