title: Prothrombin overload causes thromboembolic complications in prothrombin complex concentrates: in vitro and in vivo evidence.
authors.forename: Claudia
authors.initials: C
authors.lastname: Grundman
authors.forename: Roland
authors.initials: R
authors.lastname: Plesker
authors.forename: Manuela
authors.initials: M
authors.lastname: Kusch
authors.forename: Kay Martin
authors.initials: KM
authors.lastname: Hanschmann
authors.forename: Stefanie
authors.initials: S
authors.lastname: Eich
authors.forename: Rainer
authors.initials: R
authors.lastname: Seitz
authors.forename: Herbert
authors.initials: H
authors.lastname: König
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D001779:Blood Coagulation Factors / Q000009:adverse effects* / Q000737:chemistry; D015949:Factor IXa / Q000008:administration & dosage / Q000494:pharmacology; D002836:Hemophilia B / Q000188:drug therapy; D066298:In Vitro Techniques; D011516:Prothrombin / Q000008:administration & dosage / Q000009:adverse effects*; D011817:Rabbits; D013923:Thromboembolism / Q000209:etiology*
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates; D011516:Prothrombin; D015949:Factor IXa