title: Atropine-induced lens extrusion in an open eye surgery.
abstract: A 2-month-old male baby undergoing penetrating keratoplasty (PKP) under general anesthesia developed bradycardia and a decrease in heart rate to 53 b x min(-1) when stay sutures were taken through the superior and inferior recti. A bolus of 0.1 mg intravenous atropine resulted in tachycardia of up to 180-220 b x min(-1), which persisted for 35 min. After corneal trephination was performed the eyeball seemed to pulsate with the heartbeat. Spontaneous extrusion of the lens and vitreous occurred, which necessitated a lensectomy and vitrectomy in addition to PKP. The role of atropine in corneal transplant surgery is discussed here.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. anjolie5@hotmail.com
authors.forename: Anjolie
authors.initials: A
authors.lastname: Chhabra
authors.forename: Sailesh
authors.initials: S
authors.lastname: Mishra
authors.forename: Arun
authors.initials: A
authors.lastname: Kumar
authors.forename: Jeewan Singh
authors.initials: JS
authors.lastname: Titiyal
mesh_terms: D000768:Anesthesia, General; D001285:Atropine / Q000009:adverse effects*; D003318:Corneal Opacity / Q000601:surgery*; D016039:Corneal Transplantation; D006801:Humans; D007231:Infant, Newborn; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D009184:Mydriatics / Q000009:adverse effects*
chemical_list: D009184:Mydriatics; D001285:Atropine