Treating dyslipidemia in the elderly.
OBJECTIVE
The treatment of dyslipidemia has been dynamic over the past several years. Of special importance is the impact of recent clinical trial data on management strategies of dyslipidemia in the elderly. People 65 years and older are living longer and are the fastest growing subset of the US population, necessitating more attention to chronic disease conditions that manifest in this age group. This review addresses guidelines of lipid management, discusses data that support their use, and examines the benefits of lipid-lowering therapy in the elderly with attention to the chronic conditions that are common in this population.


RESULTS
Clinical trials completed since the publication of the 2001 National Cholesterol Education Program (NCEP) Adult Treatment Panel III guidelines support the use of lipid-lowering therapy in the elderly population. Lipid-lowering therapy has not only proven to be generally safe in the elderly, but has also proven effective in helping manage the chronic disease conditions that are common in this age group.


CONCLUSIONS
The elderly segment of our population continues to grow. Along with this growth in population is a growth in incidence of cardiovascular disease, the metabolic syndrome, chronic kidney disease, cerebrovascular disease, and diabetes mellitus. There is no known panacea for managing these chronic disease conditions; however, lipid-lowering therapy has been shown to prevent or delay the progression of these diseases and the mortality and morbidity that accompanies them.
Pohlel
Khan
K
Emory University School of Medicine, Atlanta, Georgia 30303, USA.
Grow
Parker
P
Helmy
Tarek
T
Wenger
Nanette K
NK
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D018450:Disease Progression; D050171:Dyslipidemias / Q000401:mortality / Q000628:therapy*; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D015994:Incidence; D008297:Male; D009313:National Health Programs; D010353:Patient Education as Topic; D014481:United States