title: Raynaud phenomena and migraine in two children: inclusion within a family of related disorders.
abstract: We report a case of two siblings with Raynaud phenomena and migraine, whose symptoms were successfully treated with pizotifen.
  
  
  CONCLUSIONS
  To our knowledge, this is the first case documenting the association between Raynaud phenomena and migraine in two siblings with a family history of Raynaud phenomena and ischaemic heart disease.
authors.affiliation: Department of Paediatrics, St. Thomas' Hospital, London, United Kingdom.
authors.forename: Rachel Ej
authors.initials: RE
authors.lastname: Besser
authors.forename: Colin Mm
authors.initials: CM
authors.lastname: Stern
mesh_terms: D000293:Adolescent; D002648:Child; D015897:Comorbidity; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*; D010918:Pizotyline / Q000627:therapeutic use; D011928:Raynaud Disease / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics*; D012702:Serotonin Antagonists / Q000627:therapeutic use
chemical_list: D012702:Serotonin Antagonists; D010918:Pizotyline