Association between erectile dysfunction and coronary artery disease: a case report study.
Evidence is accumulating in favor of classifying erectile dysfunction (ED) as a vascular disorder. There are three main clinical scenarios in which ED and coronary artery disease (CAD) may coexist: the patient with ED who later develops CAD, the patient with overt CAD who is casually found to have ED, and the patient with acute coronary syndrome who has normal sexual function. This study presents three cases and discusses a "putative" pathophysiological mechanism underlying all these clinical presentations. Further studies, coupling functional and structural changes of coronary circulation with those of penile (i.e., dynamic penile test) circulation in each of these situations are mandatory to support this hypothesis.
Montorsi
Piero
P
Institute of Cardiology University of Milan, Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Ravagnani
Paolo M
PM
Galli
Stefano
S
Briganti
Alberto
A
Salonia
Andrea
A
Dehò
Federico
F
Schulman
Claude
C
Montorsi
Francesco
F
D000368:Aged; D015415:Biomarkers; D001775:Blood Circulation / Q000502:physiology; D003324:Coronary Artery Disease / Q000150:complications / Q000503:physiopathology*; D003326:Coronary Circulation / Q000502:physiology; D003331:Coronary Vessels / Q000503:physiopathology; D007172:Erectile Dysfunction / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged
D015415:Biomarkers