title: Paradoxic technetium-99 methylene diphosphonate localization in malignant mesothelioma.
abstract: The literature is replete with cases of Tc-99m bone imaging agent uptake in pleural effusions. Far rarer is the report of photopenia in a pleural effusion. In this case of malignant mesothelioma, we describe a unique case of unilateral hemithoracic photopenia from a pleural effusion with concomitant uptake in the contralateral lung resulting from calcified pleural plaques. Although initially perplexing clinically, this case can be readily explained with an understanding of basic physiological principles.
authors.affiliation: Department of Radiology, Department of the Army, Madigan Army Medical Center, Tacoma, WA 98431, USA. Daniel.Reidman@nw.amedd.army.mil
authors.forename: Daniel
authors.initials: D
authors.lastname: Reidman
authors.forename: Antonio
authors.initials: A
authors.lastname: Balingit
mesh_terms: D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging* / Q000378:metabolism; D016066:Pleural Effusion, Malignant / Q000000981:diagnostic imaging* / Q000378:metabolism; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate