title: Feasibility and accuracy of real-time 3-dimensional echocardiographic assessment of ventricular septal defects.
abstract: The aim of this study was to evaluate feasibility, accuracy, and clinical applicability of real-time (RT) transthoracic 3-dimensional (3D) echocardiography (3DE) in the determination of the position, size, and shape of a ventricular septal defect (VSD). In all, 34 patients (age: 2 months-46 years), who were scheduled for surgical closure of a VSD, were enrolled in the study. VSD localization, shape, and dimensions were assessed and compared with measurements performed by the surgeon. Acquisition of RT-3DE datasets was feasible in 30 of 34 (88%) patients. Duration of 3D data acquisition was 6 +/- 2 minutes. Reconstruction time was 23 +/- 16 minutes. Localization and number of VSD were determined correctly by RT-3DE in all patients. There was a good correlation for VSD measurements between RT-3DE and operation (r = 0.95). RT-3DE allows accurate determination of VSD size, shape, and location. The short acquisition time and acceptable reconstruction time make this technique clinically applicable.
authors.affiliation: Department of Cardiology, Erasmus MC University Hospital, Rotterdam, The Netherlands. a.e.vandenbosch@erasmusmc.nl
authors.forename: Annemien E
authors.initials: AE
authors.lastname: van den Bosch
authors.forename: Derk-Jan
authors.initials: DJ
authors.lastname: Ten Harkel
authors.forename: Jackie S
authors.initials: JS
authors.lastname: McGhie
authors.forename: Jolien W
authors.initials: JW
authors.lastname: Roos-Hesselink
authors.forename: Maarten L
authors.initials: ML
authors.lastname: Simoons
authors.forename: Ad J J C
authors.initials: AJ
authors.lastname: Bogers
authors.forename: Folkert J
authors.initials: FJ
authors.lastname: Meijboom
mesh_terms: D000328:Adult; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000000981:diagnostic imaging*; D006352:Heart Ventricles / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology