Cutaneous metastases from adenocarcinoma of the rete testis.
Adenocarcinoma of the rete testis (ACRT) is extremely rare and has only been the subject of sporadic case reports, in most of which the neoplasm manifested as a scrotal mass with diffuse enlargement of the testis. Only a few cases of scrotal infiltration by a contiguous ACRT have been described. To our knowledge, none have reported distant skin metastases. We report a case of ACRT presenting with suprapubic skin metastases. The diagnosis was based on clinical and histopathological findings and supported by the results of immunohistochemical and ultrastructural studies. We discuss the differential diagnosis to this rare entity, which include metastatic adenocarcinoma, serous tumor of the testis, and mesothelioma of the tunica vaginalis.
Rubegni
Pietro
P
Department of Clinical Medicine and Immunological Sciences, Section of Dermatology, University of Siena, Italy.
Poggiali
Sara
S
De Santi
Margherita
M
Marsili
Stefania
S
Bilenchi
Roberta
R
Miracco
Clelia
C
Fimiani
Michele
M
D000230:Adenocarcinoma / Q000556:secondary* / Q000648:ultrastructure; D000368:Aged; D006801:Humans; D008297:Male; D046529:Microscopy, Electron, Transmission; D012152:Rete Testis / Q000473:pathology*; D012878:Skin Neoplasms / Q000556:secondary* / Q000648:ultrastructure; D013736:Testicular Neoplasms / Q000473:pathology*