title: [Sepsis: state of the art, diagnosis and disputable problems of classification].
abstract: Sepsis is an infection without specific features but with a high variety of clinical manifestations, this explaining various theories and opinion on this problem. Main provoker of this disease is microorganisms of the strepto-staphyllococ group producing septicopyemia. Principal morphological criterion of generalization is metastatic purulent focus. Disease produced by gram = negative bacteria is a type of the bacterial (endotoxin) shock and a main morphological criterion of an infection generalization is development of DBC-syndrome with necrosis and hemorrhages in the hypophysis-adrenal system. A separate nosological unit is a subacute septic endocarditis- immunocomplex, by its pathogenesis, disease which is necessary to differentiate with acute bacterial endocarditis in septicopiemia.
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
mesh_terms: D004731:Endotoxins / Q000378:metabolism; D016905:Gram-Negative Bacterial Infections / Q000145:classification / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D018805:Sepsis / Q000145:classification* / Q000175:diagnosis* / Q000378:metabolism; D009626:Terminology as Topic
chemical_list: D004731:Endotoxins