title: Synthesis of some phenacyl derivatives of 1-methyl-7-methoxy-beta-carboline and their behavioural study.
abstract: In the present study two phenacyl derivatives of Harmaline; 2-(7-Methoxy-1-methyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-1-(3-nitro-phenyl)-ethanone and 1-(3,4-Dihydroxy-phenyl)-2-(7-methoxy-1-methyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-ethanone were synthesized and evaluated for their effect on behaviour of mice, only meta-nitro phenacyl derivative showed activity, which can be compared with parent compound.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Saify
authors.forename: Jawaid
authors.initials: J
authors.lastname: Farhad
authors.forename: Nousheen
authors.initials: N
authors.lastname: Mushtaq
authors.forename: Fozia
authors.initials: F
authors.lastname: Noor
authors.forename: Shamoona
authors.initials: S
authors.lastname: Takween
authors.forename: Shamim
authors.initials: S
authors.lastname: Akhtar
authors.forename: Waqar
authors.initials: W
authors.lastname: Hussain
authors.forename: Shaheen A
authors.initials: SA
authors.lastname: Hussain
authors.forename: Khalid M
authors.initials: KM
authors.lastname: Khan