title: Adverse reactions associated with dapsone therapy in HIV-positive patients: a case presentation and review.
abstract: Dapsone is commonly used for the prophylaxis of Pneumocystis jiroveci pneumonia in patients with a diagnosis of HIV infection who have allergies to sulfa-based drugs. Dapsone has several adverse effects in its profile that make it a potentially dangerous second-line agent. We report an adverse effect encountered in an HIV-positive patient receiving dapsone and review the common adverse effects encountered with this alternative treatment option.
authors.affiliation: University of Oklahoma College of Pharmacy, Tulsa, USA.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Stroup
authors.forename: Johnny R
authors.initials: JR
authors.lastname: Stephens
authors.forename: Randall
authors.initials: R
authors.lastname: Reust
authors.forename: J Angela
authors.initials: JA
authors.lastname: Miller
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control*; D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003622:Dapsone / Q000009:adverse effects* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000503:physiopathology*; D006801:Humans; D008297:Male; D045363:Pneumocystis carinii / Q000472:pathogenicity*; D011020:Pneumonia, Pneumocystis / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000890:Anti-Infective Agents; D003622:Dapsone