title: [The design of an instrument furnished with hydrogen clearance technique for measuring local blood-flow and the microcomputer analysis curve on hydrogen clearance].
abstract: A new instrument, furnished with hydrogen clearance technique for measuring local blood-flow, was designed by use of new electronic components and a microcontroller. The corresponding program was developed. The curve of hydrogen clearance was sampled automatically by microcomputer, fitted into an exponential function by least square method, and then the local blood-flow was calculated. The cerebral blood-flow in the rat's striatum had been measured using the system. The fitted curve corresponds with the curve of hydrogen clearance and the obtained parameter was correct. The design of the instrument was reasonable. It can work reliably and stably. The calculated results are more accurate and they can be acquired more quickly, because the curve of hydrogen clearance is automatically sampled and analyzed by the microcomputer.
authors.affiliation: Center of Information, The First Affiliated Hospital, Hebei Medical University, Shijiazhuang 050031, China.
authors.forename: Zhenzhong
authors.initials: Z
authors.lastname: Fan
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Yi
authors.forename: Minyan
authors.initials: M
authors.lastname: Wang
authors.forename: Heshan
authors.initials: H
authors.lastname: Mei
mesh_terms: D000818:Animals; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004867:Equipment Design; D006859:Hydrogen / Q000032:analysis* / Q000493:pharmacokinetics; D008297:Male; D008838:Microcomputers; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D051381:Rats; D017208:Rats, Wistar; D012039:Regional Blood Flow / Q000502:physiology*; D012212:Rheology / Q000295:instrumentation; D012815:Signal Processing, Computer-Assisted
chemical_list: D006859:Hydrogen