A modification of the Harper-McGinty microdrive for use in chronically prepared rabbits.
We describe a modification of the Harper-McGinty microdrive for use with extracellular, microwire recording in conscious, chronically prepared rabbits. Improvements over existing designs are in ease of assembly and mechanical stability. The microdrive is easily fabricated with hand tools and readily available parts. In addition, assembly of the microdrive utilizes epoxy, avoiding the difficult task of soldering stainless steel parts. Finally, the microdrive is mounted directly to the skull enhancing mechanical stability and eliminating the need to allow space for screw travel. Importantly, this microdrive has proven to be durable as well as functional in our preparation.
McKown
Michael D
MD
Dalton Cardiovascular Research Center, Department of Biomedical Sciences, University of Missouri, Columbia, MO 65203, USA.
Schadt
James C
JC
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology; D004567:Electrodes, Implanted; D004867:Equipment Design; D008839:Microelectrodes; D011817:Rabbits; D014851:Wakefulness