title: Opening the pore hinges on proline.
authors.affiliation: Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, 4208 Molecular Biology Building, Ames, Iowa 50011, USA. amyand@iastate.edu
authors.forename: Amy H
authors.initials: AH
authors.lastname: Andreotti
mesh_terms: D000818:Animals; D001665:Binding Sites; D002462:Cell Membrane / Q000378:metabolism; D003545:Cysteine / Q000737:chemistry; D006801:Humans; D007094:Imides / Q000737:chemistry*; D015640:Ion Channel Gating / Q000502:physiology*; D007473:Ion Channels / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D007536:Isomerism; D008954:Models, Biological; D009154:Mutation; D009474:Neurons / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000378:metabolism*; D011392:Proline / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism*; D015202:Protein Engineering; D017510:Protein Folding; D017433:Protein Structure, Secondary; D044406:Receptors, Serotonin, 5-HT3 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D007094:Imides; D007473:Ion Channels; D018377:Neurotransmitter Agents; D044406:Receptors, Serotonin, 5-HT3; D011392:Proline; D003545:Cysteine