title: Suzuki-Miyaura, alpha-ketone arylation and dehalogenation reactions catalyzed by a versatile N-heterocyclic carbene-palladacycle complex.
abstract: [reaction: see text] The activity of the complex (IPr)PdCl(eta2-N,C-C12H7NMe2), 1 [IPr = (N,N'-bis(2,6-diisopropylphenyl)imidazol)-2-ylidene], in the Suzuki-Miyaura cross-coupling reaction involving unactivated aryl chlorides and triflates with arylboronic acids at room temperature in technical grade 2-propanol is described. These conditions allow for the synthesis of di- and tri-ortho-substituted biaryls in very short reaction times. This complex also displays very high activity for alpha-ketone arylation and dehalogenation reactions of activated and unactivated aryl chlorides.
authors.affiliation: Department of Chemistry, University of New Orleans, New Orleans, Louisiana 70148, USA.
authors.forename: Oscar
authors.initials: O
authors.lastname: Navarro
authors.forename: Nicolas
authors.initials: N
authors.lastname: Marion
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Oonishi
authors.forename: Roy A
authors.initials: RA
authors.lastname: Kelly
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan