Probing cell death by chemical screening.
Apoptosis occurs through precise cellular pathways, whereas necrosis is generally thought of as a nonspecific cellular response to external damage. However, identification of a chemical inhibitor of necrotic events suggests that specific molecular pathways can also trigger necrosis.
Wallach
David
D
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D009336:Necrosis; D015398:Signal Transduction / Q000187:drug effects