[Burkitt's lymphoma in a patient with systemic lupus erythematosus treated with immunosuppressive drugs. A case report].
BACKGROUND
Neoplasia and lymphoproliferative disorders are sometimes reported in patients with systemic lupus erythematosus (SLE). However, the pathophysiological link between lymphoma and SLE is still a matter of debate. We report a new case of Burkitt's lymphoma occurring in a patient treated with immunosuppressive drugs for SLE.


METHODS
A 38-year-old woman with SLE treated for 10 years with immunosuppressive drugs was admitted for the rapid onset of multiple neuritis with cranial nerves palsy, without extra-neurological involvement. The cerebrospinal fluid was normal. A bone marrow biopsy revealed Burkitt's lymphoma.


CONCLUSIONS
This is the third case reported of Burkitt's lymphoma occurring in SLE. Here we discuss the data of the literature and the possible pathophysiological links between Burkitt's lymphoma and SLE.
Bellier
C
C
Service de Médecine Interne, CHU Henri-Mondor, APHP, Créteil, France. claire.bellier@bjn.ap-hop-paris.fr
Khellaf
M
M
Lambotte
O
O
Godeau
B
B
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002051:Burkitt Lymphoma / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D003520:Cyclophosphamide / Q000009:adverse effects; D016572:Cyclosporine / Q000009:adverse effects; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D003520:Cyclophosphamide