title: Treatment of chronic plantar fasciitis with Botulinum toxin A: preliminary clinical results.
abstract: Based on recent results in chronic lateral epicondylitis we decided to investigate the efficacy of Botulinum toxin A (BTX-A) for treatment of chronic therapy resistant plantar fasciitis. Nine patients with an average duration of symptoms of 14 months and at least two prior conservative treatments received a one injection of 200 units of BTX-A (Dysport) subfascially into the painful area. The patients documented pain at rest and during weight-bearing after 2, 6, 10 and 14 weeks by a visual analogue scale. A significant reduction of pain during weight-bearing to about 50% was seen 6 weeks after injection. The effect was still present at the latest follow-up of 14 weeks. Similarly, the pain at rest was reduced to less than half of the initial value at any follow-up. All patients were satisfied and did not require further treatment.
authors.affiliation: Klinik und Poliklinik fur Orthopaedie, Universitateklinikum Hamburg-Eppendorf, Hamburg, Germany. richard.placzek@charite.de
authors.forename: Richard
authors.initials: R
authors.lastname: Placzek
authors.forename: Georg
authors.initials: G
authors.lastname: Deuretzbacher
authors.forename: A Ludwig
authors.initials: AL
authors.lastname: Meiss
mesh_terms: D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D036981:Fasciitis, Plantar / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D017060:Patient Satisfaction
chemical_list: D001905:Botulinum Toxins