Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function.
Salmonella enterica serovar Typhimurium colonizes the gut of chickens and is cleared from the intestine within about 3 weeks. Infection induces high levels of specific antibody, but B cells do not play an essential role in clearance of primary infection or in the enhanced clearance after secondary challenge.
Beal
Richard K
RK
Division of Immunology, Institute for Animal Health, Compton, Newbury, Berkshire, United Kingdom.
Powers
Claire
C
Davison
T Fred
TF
Barrow
Paul A
PA
Smith
Adrian L
AL
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001402:B-Lymphocytes / Q000502:physiology*; D002645:Chickens / Q000276:immunology*; D011201:Poultry Diseases / Q000276:immunology* / Q000382:microbiology; D012481:Salmonella Infections, Animal / Q000276:immunology* / Q000382:microbiology; D012486:Salmonella typhimurium / Q000276:immunology / Q000472:pathogenicity*
D000907:Antibodies, Bacterial