title: Chronic disorders with episodic manifestations: focus on epilepsy and migraine.
abstract: Epilepsy and migraine are chronic neurological disorders with episodic manifestations that are commonly treated in neurological practice and frequently occur together. In this review we examine similarities and contrasts between these disorders, with focus on epidemiology and classification, temporal coincidence, triggers, and mechanistically based therapeutic overlap. This investigation draws attention to unique aspects of both epilepsy and migraine, while identifying areas of crossover in which each specialty could benefit from the experience of the other.
authors.affiliation: Comprehensive Epilepsy Management Center, Department of Neurology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Sheryl R
authors.initials: SR
authors.lastname: Haut
authors.affiliation: Department of Neurology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Marcelo E
authors.initials: ME
authors.lastname: Bigal
authors.affiliation: Department of Neurology and Department of Epidemiology and Population Health, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Richard B
authors.initials: RB
authors.lastname: Lipton
mesh_terms: D002908:Chronic Disease; D004827:Epilepsy / Q000453:epidemiology* / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D015994:Incidence; D008881:Migraine Disorders / Q000453:epidemiology* / Q000503:physiopathology* / Q000628:therapy; D010507:Periodicity; D012307:Risk Factors