title: [Transcatheter closure of patent foramen ovale in patients with platypnea-orthodeoxia].
abstract: Platypnea-orthodeoxia is a rare syndrome characterized by the occurrence of dyspnea and hypoxemia on adoption of an upright posture (i.e., orthodeoxia) and by the absence of symptoms and hypoxemia in decubitus. This syndrome is frequently related to patent foramen ovale and right-to-left shunting. We describe two patients in whom patent foramen ovale with right-to-left shunting was observed on transthoracic and transesophageal echocardiography and who had platypnea-orthodeoxia in the absence of pulmonary disease. They underwent transcatheter closure using an Amplatz device. The echocardiographic diagnosis and closure procedure are discussed. These case reports demonstrate that closure of patent foramen ovale is an effective treatment for platypnea-orthodeoxia.
authors.affiliation: Servicio de Cardiología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain. jorttru@gobiernodecanarias.org
authors.forename: José R
authors.initials: JR
authors.lastname: Ortega Trujillo
authors.forename: Javier
authors.initials: J
authors.lastname: Suárez de Lezo Herreros de Tejada
authors.forename: Antonio
authors.initials: A
authors.lastname: García Quintana
authors.forename: Francisco
authors.initials: F
authors.lastname: Melián Nuez
authors.forename: Raquel
authors.initials: R
authors.lastname: Rodríguez Delgado
authors.forename: Alfonso
authors.initials: A
authors.lastname: Medina Fernández-Aceytuno
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization; D004417:Dyspnea / Q000209:etiology / Q000628:therapy; D005260:Female; D006343:Heart Septal Defects / Q000150:complications / Q000628:therapy*; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy; D011187:Posture; D013577:Syndrome