title: Formation and stability of charged amino acid clusters and the role of chirality.
abstract: Amino acid clusters have been studied by several groups and most notably magic number clusters and chiral recognition have been reported. In this work, we have studied the formation of amino acid clusters by electrospray ionization (ESI) and their stability by high-energy collision-induced dissociation (CID). Appearance sizes were determined for multiply charged clusters where the charge is either due to protons or to sodium ions. Finally, we conclude that chiral selectivity plays an important role in cluster formation but seems to be of minor importance for the fragmentation of mixed clusters.
authors.affiliation: Department of Physics and Astronomy, University of Aarhus, Aarhus, Denmark.
authors.forename: B
authors.initials: B
authors.lastname: Concina
authors.forename: P
authors.initials: P
authors.lastname: Hvelplund
authors.forename: A B
authors.initials: AB
authors.lastname: Nielsen
authors.forename: S Brøndsted
authors.initials: SB
authors.lastname: Nielsen
authors.forename: J
authors.initials: J
authors.lastname: Rangama
authors.forename: B
authors.initials: B
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Tomita
mesh_terms: D000465:Algorithms; D000596:Amino Acids / Q000737:chemistry*; D006371:Helium / Q000737:chemistry; D008968:Molecular Conformation; D011522:Protons; D012694:Serine / Q000737:chemistry; D012964:Sodium / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D011522:Protons; D006371:Helium; D012694:Serine; D012964:Sodium