title: Detection of quantitative trait loci affecting milk production traits on bovine chromosome 6 in a Chinese Holstein population by the daughter design.
abstract: Fourteen microsatellite markers with a coverage of 63.5 cM on bovine chromosome 6 were selected, and 26 sire families with 2,260 daughters were analyzed for mapping quantitative trait loci (QTL) affecting 5 milk production traits in a Chinese Holstein population. In the analyses across 26 families and within the largest significant families with a one-QTL model fitted, a QTL near BMS470 was detected that affected fat yield at the 5% experiment-wide significance level. When a 2-QTL model was fitted in the across-family analysis, it was found that there might exist 2 QTL affecting the 3 yield traits, although the exact or empirical thresholds for the significance testing were unknown. In all analyses, the results for milk yield and protein yield were generally consistent, which might have resulted from the same genetic background for milk and protein yield.
authors.affiliation: State Key Laboratory for Agrobiotechnology, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100094, China.
authors.forename: H Y
authors.initials: HY
authors.lastname: Chen
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.forename: C C
authors.initials: CC
authors.lastname: Yin
authors.forename: C K
authors.initials: CK
authors.lastname: Wang
authors.forename: W J
authors.initials: WJ
authors.lastname: Gong
authors.forename: G
authors.initials: G
authors.lastname: Mei
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics*; D002874:Chromosome Mapping / Q000662:veterinary; D005260:Female; D007774:Lactation / Q000235:genetics*; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics; D008892:Milk / Q000737:chemistry; D008894:Milk Proteins / Q000032:analysis; D010641:Phenotype; D040641:Quantitative Trait Loci / Q000235:genetics*
chemical_list: D008894:Milk Proteins