title: Association study of polymorphisms in SOCS family genes with type 1 diabetes mellitus.
abstract: Suppressors of cytokine signalling (SOCS) proteins play important roles in the negative regulation of cytokine signal. We first searched for polymorphisms in SOCS-1, SOCS-3 and SOCS-5 genes, and examined the association of the polymorphisms with type 1 diabetes (T1D). As a result, we did not find any significant associations between SOCS genes and T1D.
authors.affiliation: Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Ni
authors.forename: K
authors.initials: K
authors.lastname: Ihara
authors.forename: K
authors.initials: K
authors.lastname: Miyako
authors.forename: M
authors.initials: M
authors.lastname: Takemoto
authors.forename: M
authors.initials: M
authors.lastname: Ishimura
authors.forename: H
authors.initials: H
authors.lastname: Kohno
authors.forename: N
authors.initials: N
authors.lastname: Matsuura
authors.forename: A
authors.initials: A
authors.lastname: Yoshimura
authors.forename: T
authors.initials: T
authors.lastname: Hara
mesh_terms: D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D020641:Polymorphism, Single Nucleotide; D050826:Suppressor of Cytokine Signaling Proteins / Q000235:genetics*
chemical_list: D050826:Suppressor of Cytokine Signaling Proteins