title: [Diclofenac during prostate needle biopsy. Significant pain reduction].
abstract: BACKGROUND
  The aim of this study was to evaluate the efficacy of diclofenac to reduce pain during prostate biopsy.
  
  
  METHODS
  After prospective randomization all patients received an intrarectal lidocaine gel instillation. Group 1 (n=80) functioned as control group, group 2 (n=72) received a placebo, and group 3 (n=76) a 50 mg diclofenac suppository in addition. Patients were asked to identify their pain score (VAS 10) after the biopsy. Two weeks later, the patients were called and asked about the post-biopsy course.
  
  
  RESULTS
  Patients in the diclofenac group had significantly lower pain scores than control or placebo group patients. Another biopsy without additional anesthesia was refused by 25% of the control group and 34% of the placebo group, but only by 11% of the diclofenac group (p<0.05).
  
  
  CONCLUSIONS
  The preinterventional administration of diclofenac suppositories is a simple but efficient procedure for pain reduction in patients who undergo prostate biopsy.
authors.affiliation: Abteilung für Urologie, Asklepios Klinik Barmbek, Hamburg. thorsten.bach@hansenet.de
authors.forename: T
authors.initials: T
authors.lastname: Bach
authors.forename: R
authors.initials: R
authors.lastname: Tauber
mesh_terms: D000700:Analgesics / Q000008:administration & dosage*; D000772:Anesthesia, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001707:Biopsy, Needle; D004008:Diclofenac / Q000008:administration & dosage*; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine; D008297:Male; D010147:Pain Measurement; D010342:Patient Acceptance of Health Care; D017060:Patient Satisfaction; D011292:Premedication; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D013488:Suppositories
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D013488:Suppositories; D004008:Diclofenac; D008012:Lidocaine