title: Design and validation of an analyser to measure sulphur hexafluoride gas during respiration.
abstract: The study presents the results of the development of an analyser to measure sulphur hexafluoride (SF6) gas in breathing circuits, for application is studies of lung function. The analyser consists of an in-line breathing circuit measurement transducer and a compact unit for signal treatment. The detector unit of the analyser consists of a near-infrared light source, a bandpass filter and a pyro-electrical detector. When incremental steps of SF6 gas between 0 and 2% were presented to the analyser, the maximum deviation from the theoretical calibration curve was calculated to be 0.01% SF6. The step response of the analyser (10-90%) was 250 ms. The sensitivity of the analyser to ambient temperature was 0.01% SF6 degrees C(-1) in the range between 0 and 2% SF6. It is concluded that the analyser presented is accurate, and has a sufficient response speed to be used in clinical measurement settings. Furthermore, the analyser is resistant to changes in temperature, gas flow, orientation and movement, which are likely to occur in clinical measurement settings.
authors.affiliation: Center of Optical Diagnostics & Therapy and the Surgical Intensive Care Unit, Erasmus Medical Centre Rotterdam, The Netherlands. jkkkanhai@hotmail.com
authors.forename: J K K
authors.initials: JK
authors.lastname: Kanhai
authors.forename: F
authors.initials: F
authors.lastname: Eijskoot
authors.forename: E G J
authors.initials: EG
authors.lastname: Reinders
authors.forename: H A
authors.initials: HA
authors.lastname: Bruining
authors.forename: G J
authors.initials: GJ
authors.lastname: Puppels
mesh_terms: D001944:Breath Tests / Q000295:instrumentation / Q000379:methods*; D004582:Electronics, Medical; D004867:Equipment Design; D006801:Humans; D008176:Lung Volume Measurements / Q000379:methods*; D019265:Spectroscopy, Near-Infrared / Q000379:methods; D013459:Sulfur Hexafluoride
chemical_list: D013459:Sulfur Hexafluoride