The first detection of CTX-M-14 extended-spectrum beta-lactamase among diverse beta-lactamase-producing Proteus mirabilis clinical isolates.
CTX-M-14- and -2-like extended-spectrum beta-lactamases were detected in 5 and 1 Proteus mirabilis isolates, respectively, among 92 non-duplicate strains tested from December 2002 to September 2003. This is the first report of the CTX-M-14 enzyme in P. mirabilis to the best of our knowledge and suggests that the CTX-M-type enzyme is gradually spreading to this species. bla(TEM), bla(SHV-1), and/or bla(OXA-10) alleles were also detected in 35 ampicillin-resistant isolates tested.
Yong
Dongeun
D
Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul 120-752, Korea.
Lim
Young Sik
YS
Roh
Kyoung Ho
KH
Choi
Yeoung Seon
YS
Park
Doe-Young
DY
Yum
Jong Hwa
JH
Kim
June Myung
JM
Lee
Kyungwon
K
Chong
Yunsop
Y
D000328:Adult; D000368:Aged; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D017720:Molecular Epidemiology; D011512:Proteus Infections / Q000382:microbiology*; D011513:Proteus mirabilis / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000032:analysis* / Q000235:genetics
D004269:DNA, Bacterial; C071167:beta-lactamase CTX-2; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases