Poly-N-methylated alpha-peptides: synthesis and X-ray structure determination of beta-strand forming foldamers.
The first high resolution X-ray structure determination of poly-N-methylated alpha-peptides, a class of peptides widely used in biomedical research, is described; it shows that these molecules adopt a beta-strand conformation.
Zhang
Suode
S
Department of Chemistry, Organic Chemistry, Uppsala University, S-75124, Uppsala, Sweden.
Prabpai
Samran
S
Kongsaeree
Palangpon
P
Arvidsson
Per I
PI
D035843:Biomedical Research / Q000379:methods*; D018360:Crystallography, X-Ray / Q000379:methods; D006860:Hydrogen Bonding; D008745:Methylation; D008968:Molecular Conformation; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary
D010455:Peptides