title: Dramatic improvement of penile venous leakage upon testosterone administration. A case report and review of literature.
abstract: The main effect of testosterone was long-time assumed to be on sexual interest and, indirectly, on erectile function. Newer insights demonstrate that testosterone deficiency impairs the anatomical, ultrastructural, biological and physiological/functional substrate of penile erection, which can be, at least in part, restored by normalization of plasma testosterone levels. This is a report on a 56-year-old man suffering from diabetes mellitus type II and metabolic syndrome, who had complaints of a severe erectile dysfunction because of venous leakage, confirmed by pharmaco-cavernosography. He was also testosterone deficient (1.8 ng ml(-1)). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage.
authors.affiliation: Clinic of Urology/Andrology, Segeberger Kliniken, Norderstedt-Hamburg, Germany. yassin@t-online.de
authors.forename: A A
authors.initials: AA
authors.lastname: Yassin
authors.forename: F
authors.initials: F
authors.lastname: Saad
mesh_terms: D000375:Aging / Q000097:blood / Q000502:physiology; D000728:Androgens / Q000627:therapeutic use*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology; D007172:Erectile Dysfunction / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D018783:Impotence, Vasculogenic / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000503:physiopathology; D008875:Middle Aged; D010413:Penis / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011859:Radiography; D013739:Testosterone / Q000097:blood / Q000172:deficiency* / Q000502:physiology / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000728:Androgens; D013739:Testosterone