title: The effect of centrally acting drug chlorpromazine on the secretion of prolactin in the lizard, Uromastix hardwickii.
abstract: This investigation deals with the effect of chlorpromazine, on Uromastix hypophyseal prolactin. Administration of the doses 0.125, 0.25, 0.5 and 1 mg chlorpromazine per 3 days per animal resulted in a significant increase pigeon crop-sac response (p<0.01). The degree of proliferation of crop-gland showed a dose dependent threshold. Chlorpromazine binds to the target cell specific receptors of PRL and GH, both at the same time.
authors.affiliation: Department of Physiology, University of Karachi, Karachi-75270, Pakistan.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Ahmad
authors.forename: Ruqaiya
authors.initials: R
authors.lastname: Hasan
authors.forename: Sohail
authors.initials: S
authors.lastname: Yameen
authors.forename: Mansoor
authors.initials: M
authors.lastname: Ahmad