title: Bubble packing application in computerized planning of cryosurgery.
abstract: Among many factors, the effectiveness of the cryoprocedure is determined by the quality of the cryoprobes layout. A computerized planning tool for optimizing this layout has the potential of improving the outcome of cryosurgery, reducing post-operative complications, and reducing the cost of the clinical operation. As part of an ongoing effort to develop planning tools for cryosurgery, the current study takes a novel approach, based on bubble-packing method. This study shows that the application of bubble-packing shortens runtime by an order of magnitude. In this study, the bubble-packing method is integrated with bioheat transfer simulations to demonstrate the quality of planning.
authors.affiliation: Department of Biomedical Engineering, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA 15217, USA.
authors.forename: Daigo
authors.initials: D
authors.lastname: Tanaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Shimada
authors.forename: Yoed
authors.initials: Y
authors.lastname: Rabin
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D003452:Cryosurgery / Q000295:instrumentation*; D006801:Humans; D014481:United States