title: Research of stimulants and anabolic steroids in dietary supplements.
abstract: The purpose of this study was to analyze the composition of 103 dietary supplements bought on the internet. The supplements were dispatched in four different categories according to their announced contents [creatine, prohormones, "mental enhancers" and branched chain amino acids (BCAA)]. All the supplements were screened for the presence of stimulants and main anabolic steroids parent compounds. At the same time, the research was focused on the precursors and metabolites of testosterone and nandrolone. The study pointed out three products containing an anabolic steroid, metandienone, in a very high amount. The ingestion of such products induced a high quantity of metandienone metabolites in urines that would be considered as a positive antidoping test. The results have also shown that one creatine product and three "mental enhancers" contained traces of hormones or prohormones not claimed on the labels and 14 prohormone products contained substances other than those indicated by the manufacturer. The oral intake of the creatine product revealed the presence of the two main nandrolone metabolites (19-norandrosterone and 19-noretiocholanolone) in urine.
authors.affiliation: Laboratoire Suisse d'Analyse du Dopage, Institut Universitaire de Médecine Légale, Département Universitaire de Médecine et Santé Communautaire, Lausanne, Switzerland. norbert.baume@hospvd.ch
authors.forename: N
authors.initials: N
authors.lastname: Baume
authors.forename: N
authors.initials: N
authors.lastname: Mahler
authors.forename: M
authors.initials: M
authors.lastname: Kamber
authors.forename: P
authors.initials: P
authors.lastname: Mangin
authors.forename: M
authors.initials: M
authors.lastname: Saugy
mesh_terms: D045930:Anabolic Agents / Q000032:analysis*; D000697:Central Nervous System Stimulants / Q000032:analysis*; D019587:Dietary Supplements / Q000032:analysis* / Q000600:supply & distribution; D004300:Doping in Sports; D004340:Drug Contamination; D004348:Drug Labeling; D006801:Humans; D020407:Internet; D008696:Methandrostenolone / Q000032:analysis*; D004366:Nonprescription Drugs / Q000737:chemistry* / Q000600:supply & distribution; D010865:Pilot Projects; D013177:Sports; D013256:Steroids
chemical_list: D045930:Anabolic Agents; D000697:Central Nervous System Stimulants; D004366:Nonprescription Drugs; D013256:Steroids; D008696:Methandrostenolone