title: [Insulin treatment in elder patients with diabetes].
abstract: Diabetes is a highly expanding health problem in Japan, especially for older people. The prevalence of glucose intolerance and diabetes increases with age. A postprandial hyperglycemia is the primary clinical manifestation. In older diabetic patients, atherosclerotic complications (macroangiopathies), as well as microangiopathies, are significant problems, threatening their quality of life. Though insulin therapy requires some special considerations, insulin is indicated for any patients with a poor glycemic control with oral agents. Single or multiple dose (s) of insulin injection therapy is selected for each patient to prevent symptomatic hyperglycemia, or to achieve near-normal glycemic control. Also, to maintain the quality of life for these older patients, hypoglycemia, as well as hyperglycemia, should be avoided. Newly developed insulin analogue (s) may be more appropriate for preventing hypoglycemia. Another method of prevention and treatment of hypoglycemia are discussed in this article.
authors.affiliation: Division of Diabetes & Metabolism, Department of Internal Medicine, Hyogo College of Medicine.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Hamaguchi
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Namba
mesh_terms: D000368:Aged; D050197:Atherosclerosis; D015190:Blood Glucose Self-Monitoring; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy*; D006801:Humans; D006943:Hyperglycemia; D007003:Hypoglycemia / Q000139:chemically induced / Q000517:prevention & control; D007328:Insulin / Q000008:administration & dosage* / Q000009:adverse effects; D019518:Postprandial Period; D011788:Quality of Life
chemical_list: D007328:Insulin