title: Primary spinal extranodal Hodgkin's disease at two levels.
abstract: About 90% of Hodgkin's disease cases originate from lymph nodes whereas 10% from extranodal regions. Patients rarely present with spinal cord compression due to epidural Hodgkin's disease. Primary spinal extradural Hodgkin's disease which does not have any other organ involvement in the body is even rarer. A 39-year-old male patient who complained of lumbar pain had normal findings upon neurological examination. Radiological examination revealed a mass on the epidural space at level L3 and the involvement of the vertebral corpus accompanied by the involvement of C6 vertebral body. Primary focus could not be identified despite further investigation. The patient underwent L3 laminectomy and posterior decompression and biopsy was obtained from the lesion extending to epidural space. The pathological result was reported as lymphocyte dominant type Hodgkin's disease. Flow cytometry was performed to the lesion, also. The patient was evaluated as Stage 4A according to Ann Arbor classification. Postoperative radiotherapy was applied to lumbar and cervical region. In the literature we have not come across any case of primary spinal extranodal Hodgkin's disease with involvement at two levels. In conclusion, although it might be extremely rare, primary spinal extranodal Hodgkin's disease with involvement at two levels might be observed.
authors.affiliation: Zonguldak Karaelmas Universitesi, Tip Fakültesi Hastanesi Nöroşirürji AD, Zonguldak 67600, Turkey. cagavif@yahoo.com
authors.forename: Ferda
authors.initials: F
authors.lastname: Cağavi
authors.forename: Murat
authors.initials: M
authors.lastname: Kalayci
authors.forename: Ishak Ozel
authors.initials: IO
authors.lastname: Tekin
authors.forename: Gamze
authors.initials: G
authors.lastname: Numanoğlu
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Cağavi
authors.forename: Sanser
authors.initials: S
authors.lastname: Gül
authors.forename: Bektaş
authors.initials: B
authors.lastname: Açikgöz
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae; D006689:Hodgkin Disease / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D013125:Spinal Neoplasms / Q000473:pathology* / Q000628:therapy