title: [Long-term results of xenoscleroplasty of the posterior pole of the eyeball in the treatment of patients with progressive myopia].
abstract: The study deals with the development of an effective, atraumatic and easy-to-use treatment for patients with progressive myopia, by using a discoid xenograft. The treatment involves implantation of a discoid xenograft to the episclera of the posterior pole of the eye. The xenograft is a white disk prepared from the treated bovine pericardium and it has 2 mm in thickness and a diameter of 13 mm. Clinical studies were performed in 89 patients (161 eyes) operated on by the proposed procedure, by evaluating the stabilized progression of myopia 4 years later. In the late period of a follow-up, the stabilization effect was 88.3 to 92.6% in relation to the degree of myopia. There was evidence for increases in the thickness of the sclera (and its acoustic density) on the posterior pole of the eye, for improved regional hemodynamics and better electrophysiological functions of the retina in the postoperative period. Xenoscleroplasty of the posterior pole of the eye with a bovine pericardial xenograft is an easy-to-use, pathogenetically oriented, highly effective, and safe treatment in patients with progressive myopia.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Cheglakov
authors.forename: I E
authors.initials: IE
authors.lastname: Ioshin
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Cheglakov
authors.forename: G L
authors.initials: GL
authors.lastname: Moiseenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002417:Cattle; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D010496:Pericardium / Q000637:transplantation; D012029:Refraction, Ocular; D016639:Scleroplasty / Q000379:methods*; D012720:Severity of Illness Index; D014183:Transplantation, Heterologous; D016896:Treatment Outcome; D014792:Visual Acuity