title: Allele frequencies of six miniSTR loci of three ethnic populations in Singapore.
abstract: MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. This study investigated the allele frequency of six miniSTR loci, D1S1677, D2S441, D4S2364, D10S1248, D14S1434 and D22S1045, in three Singapore populations. All loci showed a moderate degree of polymorphism with observed heterozygosity >0.6 for all three populations. The allele frequencies, forensic parameters and heterozygosity comparison with other CODIS STR in similar populations are presented.
authors.affiliation: Defence Medical and Environmental Research Institute, DSO National Laboratories, 27 Medical Drive, Singapore 117510, Singapore. ritayong@dso.org.sg
authors.forename: R Y Y
authors.initials: RY
authors.lastname: Yong
authors.forename: L S H
authors.initials: LS
authors.lastname: Gan
authors.forename: M D
authors.initials: MD
authors.lastname: Coble
authors.forename: E P H
authors.initials: EP
authors.lastname: Yap
mesh_terms: D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D016133:Polymerase Chain Reaction; D012846:Singapore; D020080:Tandem Repeat Sequences