Colorimetric determination of indolic drugs.
A colorimetric method has been developed for the quantitative determination of the rescinnamine, reserpine upto (-10(-4M)), Yohimbine on complexation with bromothymol blue. The coloured complexes exhibit absorption maxima in the region 415-416 nm. The RSD (Relative Standard Deviation) of the method is 2.02%. The method is simple, easy, rapid and convenient for routine analysis of the indolic drugs.
Azhar
Iqbal
I
Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
Mazhar
Farah
F
Manzar
Qazi Nawab
QN
Hussain
Iftekhar
I
Shamim
Sumbul
S
D001979:Bromthymol Blue / Q000737:chemistry; D002725:Chloroform; D003124:Colorimetry / Q000379:methods; D004583:Electrons; D026121:Indole Alkaloids / Q000032:analysis; D007211:Indoles / Q000032:analysis* / Q000737:chemistry; D008968:Molecular Conformation; D015203:Reproducibility of Results; D012110:Reserpine / Q000031:analogs & derivatives / Q000032:analysis; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013678:Technology, Pharmaceutical / Q000379:methods; D013997:Time Factors; D015016:Yohimbine / Q000032:analysis
D026121:Indole Alkaloids; D007211:Indoles; D012997:Solvents; D015016:Yohimbine; D002725:Chloroform; D012110:Reserpine; C084826:rescinnamine; D001979:Bromthymol Blue