title: Severe Pseudomonas aeruginosa keratitis shortly after initiation of corneal refractive therapy.
abstract: OBJECTIVE
  To report the development of severe ulcerative keratitis in an adolescent, shortly after initiating corneal refractive therapy.
  
  
  METHODS
  A teenager developed severe ulcerative keratitis shortly after being fitted with reverse-geometry contact lenses. The contact lenses were worn daily and only one night before the occurrence of severe ulcerative keratitis. Pseudomonas aeruginosa was identified as the causative organism.
  
  
  RESULTS
  The patient was treated with intensive, fortified antibiotics with gradual resolution of the corneal ulcer, leaving a permanent central stromal scar.
  
  
  CONCLUSIONS
  Corneal refractive therapy contact lenses can cause severe bacterial keratitis even after a short wearing time. Significant caution should be used before prescribing corneal refractive therapy lenses, and informed consent should include potential sight-threatening infectious keratitis.
authors.affiliation: Goldschleger Eye Institute, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel.
authors.forename: Ayelet
authors.initials: A
authors.lastname: Priel
authors.forename: Aaron
authors.initials: A
authors.lastname: Grinbaum
authors.forename: Irina S
authors.initials: IS
authors.lastname: Barequet
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects* / Q000382:microbiology; D003320:Corneal Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009216:Myopia / Q000628:therapy*; D009883:Ophthalmic Solutions; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions