[Diclofenac during prostate needle biopsy. Significant pain reduction].
BACKGROUND
The aim of this study was to evaluate the efficacy of diclofenac to reduce pain during prostate biopsy.


METHODS
After prospective randomization all patients received an intrarectal lidocaine gel instillation. Group 1 (n=80) functioned as control group, group 2 (n=72) received a placebo, and group 3 (n=76) a 50 mg diclofenac suppository in addition. Patients were asked to identify their pain score (VAS 10) after the biopsy. Two weeks later, the patients were called and asked about the post-biopsy course.


RESULTS
Patients in the diclofenac group had significantly lower pain scores than control or placebo group patients. Another biopsy without additional anesthesia was refused by 25% of the control group and 34% of the placebo group, but only by 11% of the diclofenac group (p<0.05).


CONCLUSIONS
The preinterventional administration of diclofenac suppositories is a simple but efficient procedure for pain reduction in patients who undergo prostate biopsy.
Bach
T
T
Abteilung für Urologie, Asklepios Klinik Barmbek, Hamburg. thorsten.bach@hansenet.de
Tauber
R
R
D000700:Analgesics / Q000008:administration & dosage*; D000772:Anesthesia, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001707:Biopsy, Needle; D004008:Diclofenac / Q000008:administration & dosage*; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine; D008297:Male; D010147:Pain Measurement; D010342:Patient Acceptance of Health Care; D017060:Patient Satisfaction; D011292:Premedication; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D013488:Suppositories
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D013488:Suppositories; D004008:Diclofenac; D008012:Lidocaine