Higher preoperative D-dimer value remain high postoperatively in patients with rheumatoid arthritis compared with those with osteoarthrosis.
The differences in hemostatic condition between patients with inflammatory rheumatoid arthritis (RA) and noninflammatory osteoarthrosis (OA) were studied. Twenty-six patients undergoing total knee arthroplasty were enrolled. Compared with OA patients, RA patients showed a higher platelet count and D-dimer value preoperatively, and D-dimer remained high for 1 week after the operation. Patients with OA showed popular DD change, with the lowest value observed before the operation, and a gradual increase for 1 week after the operation. The highest value of thrombin-antithrombin complex was observed immediately after the operation. Fibrinogen and the clot rate at 1 week after operation were higher in both patient groups. We concluded that patients with RA showed different perioperative hemostatic change than patients with OA.
Mukubo
Yukiko
Y
Tokyo Women's Medical University, Medical Center East, 2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan.
Kawamata
Miwako
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000601:surgery; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000097:blood* / Q000601:surgery; D020246:Venous Thrombosis / Q000097:blood
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D