title: Fanconi anemia manifesting as a squamous cell carcinoma of the hard palate: a case report.
abstract: Fanconi anemia is a rare autosomal recessive disorder characterized by various congenital malformations, progressive bone marrow failure at a very young age and of solid tumors development. The authors present a rare case of a squamous cell carcinoma of the hard palate in a Fanconi Anaemia patient. The atypical clinical manifestation rendered the diagnosis more difficult. This case, for age of appearance, sex and localization, is unique in international literature. We recommend a quarterly follow up of the oral-rhino-pharynx complex in FA patients and to consider as carcinomas, all oral lesions that last more than two weeks.
authors.affiliation: U,O, Maxillofacial Surgery, Catholic University Medical School, Rome, Italy. giuliogasparini@yahoo.it
authors.forename: Giulio
authors.initials: G
authors.lastname: Gasparini
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Longobardi
authors.forename: Roberto
authors.initials: R
authors.lastname: Boniello
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Petrillo
authors.forename: Sandro
authors.initials: S
authors.lastname: Pelo
mesh_terms: D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005199:Fanconi Anemia / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019647:Oral Surgical Procedures / Q000379:methods; D010157:Palatal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D021362:Palate, Hard; D014057:Tomography, X-Ray Computed