title: [Drugs contraindicated in children: a study of drug prescriptions in ambulatory medicine in the south of France (Aude Department)].
abstract: OBJECTIVE
  The aim of this study was to describe prescriptions of drugs contra-indicated in children according to the summary product characteristics (SPC) of the drugs.
  
  
  METHODS
  An exhaustive cross-sectional study based on the data used by the French Health Insurance in the Aude Department (France) during 2001 was carried out to identify all instances where children under the age of 15 years were prescribed a drug that stated in its SPC that its use in this age group was contraindicated.
  
  
  RESULTS
  The prescription of drugs stated as being contraindicated in children under the age of 15 years involved 4316 children. The incidence rate was 116 per 1000 child-years. It was patently obvious for two classes of drugs: nasal decongestants (21.0% of prescriptions) and non-steroidal anti-inflammatory drugs (16.9%). These prescriptions were made by 610 physicians, of which 70% were general practitioners, 8% dentists and 3% paediatricians.
  
  
  CONCLUSIONS
  This study shows a high incidence of children receiving contraindicated drugs in Aude department in France. This work highlights the need for, first, the widespread dissemination of information on the good use of drugs in children and, secondly, specific clinical trials performed in children.
authors.affiliation: Echelon Local du Service Medical de l'Aude, Caisse Nationale de l'Assurance Maladie des Travailleurs Salaries, Carcassonne, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Damagnez
authors.forename: André
authors.initials: A
authors.lastname: Magnouat
authors.forename: Jacques
authors.initials: J
authors.lastname: Niezborala
authors.forename: Michel
authors.initials: M
authors.lastname: Laroze
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Gaston
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Montastruc
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005602:France; D006801:Humans; D007223:Infant; D004364:Pharmaceutical Preparations
chemical_list: D004364:Pharmaceutical Preparations