title: An intramolecular Diels-Alder approach to the eunicellins: enantioselective total syntheses of ophirin B and astrogorgin.
abstract: The enantioselective syntheses of the eunicellins ophirin B and astrogorgin have been completed. Ring-closing metatheses provide efficient access to the oxonene rings, and highly diastereoselective intramolecular Diels-Alder reactions resulted in the formation of the hydrobenzofuran portion of the molecules.
authors.affiliation: Department of Chemistry, University of North Carolina at Chapel Hill, 27599-3290, USA. crimmins@email.unc.edu
authors.forename: Michael T
authors.initials: MT
authors.lastname: Crimmins
authors.forename: Brandon H
authors.initials: BH
authors.lastname: Brown
authors.forename: Hilary R
authors.initials: HR
authors.lastname: Plake
mesh_terms: D000818:Animals; D003063:Cnidaria / Q000737:chemistry; D004224:Diterpenes / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; C492960:ophirin B