Analytical and biological variables influencing quantitative hepatitis C virus (HCV) measurement in HIV-HCV coinfection.
The present review considers issues pertaining to the precision and variability of quantitative hepatitis C virus (HCV) measurement in general, outlines the characteristics of HCV RNA in HIV-HCV coinfection and evaluates those factors which may affect this measure. The clinical relevance of accurate HCV measurement in HIV-HCV coinfection is discussed.
Cooper
C L
CL
University of Ottawa, Ottawa, Canada. ccooper@ottawahospital.on.ca
Cooper
Curtis L
CL
MacPherson
Paul
P
Cameron
William
W
D044966:Anti-Retroviral Agents / Q000494:pharmacology / Q000627:therapeutic use; D018450:Disease Progression; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D006526:Hepatitis C / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D011237:Predictive Value of Tests; D012367:RNA, Viral / Q000187:drug effects* / Q000378:metabolism; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D044966:Anti-Retroviral Agents; D012367:RNA, Viral