title: Treatment for simple plantar verrucae: monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone.
abstract: Verrucae are small, benign, highly vascular epithelial neoplasms that occur singly or in a multiple presentation. Plantar verrucae are usually caused by infection with human papillomavirus types 1, 2, and 4. A clinical trial was conducted to assess the safety and efficacy of monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone in the treatment of simple plantar verrucae. Of 57 patients enrolled in the study, 26 were in the monochloroacetic acid and 10% formaldehyde group and 31 were in the 10% formaldehyde alone group. The overall cure rate for this population was 61.4%. There was no statistically significant difference in the cure rate between treatment groups.
authors.affiliation: Department of Medicine, New York College of Podiatric Medicine, New York, NY, USA.
authors.forename: Maureen B
authors.initials: MB
authors.lastname: Jennings
authors.forename: James
authors.initials: J
authors.lastname: Ricketti
authors.forename: John
authors.initials: J
authors.lastname: Guadara
authors.forename: Wendy
authors.initials: W
authors.lastname: Nach
authors.forename: Susan
authors.initials: S
authors.lastname: Goodwin
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D000328:Adult; D004202:Disinfectants / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy*; D005557:Formaldehyde / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D014860:Warts / Q000188:drug therapy*
chemical_list: D000085:Acetates; D004202:Disinfectants; D005557:Formaldehyde; C006972:chloroacetic acid