title: Effects of diet on clinical signs of exocrine pancreatic insufficiency in dogs.
abstract: OBJECTIVE
  To assess the effects of dietary modification on clinical signs of exocrine pancreatic insufficiency (EPI) in dogs.
  
  
  METHODS
  Blinded randomized crossover study.
  
  
  METHODS
  21 dogs with EPI.
  
  
  METHODS
  Dogs were fed the diet they received at home for 2 weeks. Thereafter, they received 3 special diets (a high-fat diet, a high-fiber diet, and a highly digestible low-residue diet) for 3 weeks each. Owners scored dogs daily for the last 2 weeks of each 3-week period for severity of 6 clinical signs including appetite, defecation frequency, consistency of feces, borborygmus, flatulence, and coprophagia. An EPI index was calculated for each dog by adding the daily scores for each clinical sign.
  
  
  RESULTS
  Significant differences in daily EPI indices among diets were observed in 20 dogs. The original diet appeared to be the most suitable in 8 dogs, whereas the high-fat diet was most suitable in 5 dogs, the high-fiber diet was most suitable in 4 dogs, and the low-residue diet was most suitable in 2 dogs. In 1 dog, the lowest EPI index score was the same during the original diet and the high-fat diet feeding periods. One dog did not complete the feeding period for the high-fiber diet. Differences in mean EPI indices among diets were not significant.
  
  
  CONCLUSIONS
  Results indicated that responses to different diets varied among individual dogs. Because responses to the feeding regimens were unpredictable, it is suggested that feeding regimens be individually formulated for dogs with EPI.
authors.affiliation: Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, University of Helsinki, Hämeentie 57, 00014 Finland.
authors.forename: Elias
authors.initials: E
authors.lastname: Westermarck
authors.forename: Maria E
authors.initials: ME
authors.lastname: Wiberg
mesh_terms: D000818:Animals; D001066:Appetite / Q000187:drug effects / Q000502:physiology; D003303:Coprophagia / Q000453:epidemiology; D018592:Cross-Over Studies; D003672:Defecation / Q000187:drug effects / Q000502:physiology; D004041:Dietary Fats / Q000008:administration & dosage*; D004043:Dietary Fiber / Q000008:administration & dosage*; D004283:Dog Diseases / Q000178:diet therapy*; D004285:Dogs; D010188:Exocrine Pancreatic Insufficiency / Q000178:diet therapy / Q000662:veterinary*; D005243:Feces / Q000737:chemistry; D005414:Flatulence / Q000453:epidemiology / Q000662:veterinary; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D004041:Dietary Fats; D004043:Dietary Fiber