Recent developments in membrane-protein structural genomics.
Recent work has identified the topology of almost all the inner membrane proteins in Escherichia coli, and advances in nuclear magnetic resonance spectroscopy now allow the determination of alpha-helical membrane protein structures at high resolution. Together these developments will help overcome the current limitations of high-throughput determination of membrane protein structures.
Gao
Fei Philip
FP
Department of Chemistry and Biochemistry, and the National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310, USA. gao@magnet.fsu.edu
Cross
Timothy A
TA
D030562:Databases, Protein; D015870:Gene Expression; D016678:Genome; D023281:Genomics; D008565:Membrane Proteins / Q000737:chemistry* / Q000235:genetics*; D019906:Nuclear Magnetic Resonance, Biomolecular
D008565:Membrane Proteins