Granulocyte-macrophage colony-stimulating factor for perianal hidradenitis suppurativa: report of a case.
Perianal hidradenitis suppurativa is a chronic inflammatory disease associated with significantly high morbidity, which severely affects the quality of life of those patients suffering from it. We describe a 46-year-old patient with extensive, severe gluteal and perianal PHS of 28 years duration. Repeated wide excisions, fistulotomies, treatments with hyperbaric oxygen, and finally a diverting colostomy were unsuccessful. A new form of treatment with repeated perilesional injections of granulocyte-macrophage colony-stimulating factor, in conjunction with surgical procedures, was performed with excellent results.
Sharon-Guidetti
Ahuva
A
Department of Internal Medicine F, Assaf Harofeh Medical Center, Zerifin, Israel.
Ziv
Yehiel
Y
Kummer
Esther
E
Yogev
Robert
R
Halevy
Ariel
A
D001003:Anal Canal; D003125:Colostomy; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D017497:Hidradenitis Suppurativa / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007267:Injections; D008297:Male; D008875:Middle Aged; D014945:Wound Healing
D016178:Granulocyte-Macrophage Colony-Stimulating Factor