title: [Today's tuberculosis: the specific features of its pathogen, clinical picture, and treatment].
abstract: Clinical Mycobacterium tuberculosis (MBT) strains (their genotype, drug resistance, and virulence) and the characteristics of their caused processes were studied. More than a half the studied MBT isolates belonged to the genetic family Beijing. As compared with mycobacteria of individual genotypes, they showed a significantly higher rate of multidrug resistance, polyresistance, and a high virulescence and caused more common and frequently progressive pulmonary lesions requiring the use of large-dose isoniazid and second-line drugs and early surgical treatment.
authors.forename: L A
authors.initials: LA
authors.lastname: Skvortsova
authors.forename: M V
authors.initials: MV
authors.lastname: Pavlova
authors.forename: n V
authors.initials: nV
authors.lastname: Sapozhnikova
authors.forename: B I
authors.initials: BI
authors.lastname: Veshnevskiĭ
authors.forename: O V
authors.initials: OV
authors.lastname: Narvskaia
mesh_terms: D000904:Antibiotics, Antitubercular / Q000627:therapeutic use*; D005838:Genotype; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D011110:Polymorphism, Genetic / Q000235:genetics; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000235:genetics / Q000382:microbiology*
chemical_list: D000904:Antibiotics, Antitubercular