title: Nocardiosis in a patient with primary anti-phospholipid syndrome.
abstract: Antiphospholipid syndrome is an autoimmune disease that is characterised by tendency to thrombosis, obstetrical and hematological complications. Corticosteroids may be useful for therapy of some features of this syndrome, such as thrombocytopenia. Nocardia is an important opportunistic infectious agent in immunocompromised hosts, i.e. in patients taking corticosteroids. It is important to be aware of these rare complications, which are correlated with the prognosis. In this paper, we report a patient with primary anti-phospholipid syndrome treated by corticosteroid, who developed disseminated nocardiosis.
authors.affiliation: Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, 22100 Turkey. msoy_2000@yahoo.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Soy
authors.forename: Müşerref Tatman
authors.initials: MT
authors.lastname: Oktun
authors.forename: Nermin
authors.initials: N
authors.lastname: Tunçbilek
authors.forename: Nilay
authors.initials: N
authors.lastname: Ermantaş
authors.forename: Omür
authors.initials: O
authors.lastname: Okten
authors.forename: Gündeniz
authors.initials: G
authors.lastname: Altinay
authors.forename: Burhan
authors.initials: B
authors.lastname: Turgut
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000188:drug therapy*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002738:Chloroquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008775:Methylprednisolone / Q000009:adverse effects*; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D013921:Thrombocytopenia / Q000188:drug therapy* / Q000209:etiology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; C023676:chloroquine diphosphate; D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002738:Chloroquine; D008775:Methylprednisolone