Reduced expression of perchloric acid-soluble protein after partial hepatectomy in rats.
We examined the expression of perchloric acid-soluble protein (PSP) during liver regeneration after partial hepatectomy (PH) in rats. Liver regeneration was almost complete at 7-d after PH. Expression of PSP protein and mRNA decreased and then gradually increased during liver regeneration. An immunohistochemical study showed that PSP is distributed in cytosol and nuclei in normal liver, but localization in the nuclei was not be recognized in the regenerated liver.
Kanouchi
Hiroaki
H
Department of Biochemistry, Kawasaki Medical School, Okayama, Japan. kanouchihiroaki@mac.com
Taga
Masaki
M
Okamoto
Takeaki
T
Yamasaki
Masao
M
Oka
Tatsuzo
T
Yamada
Koji
K
Tone
Shigenobu
S
Minatogawa
Yohsuke
Y
D000818:Animals; D005786:Gene Expression Regulation / Q000235:genetics*; D006360:Heat-Shock Proteins / Q000235:genetics* / Q000378:metabolism*; D006498:Hepatectomy; D007150:Immunohistochemistry; D008115:Liver Regeneration / Q000235:genetics; D008297:Male; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012260:Ribonucleases / Q000235:genetics* / Q000378:metabolism*
D006360:Heat-Shock Proteins; D012333:RNA, Messenger; C097211:Rida protein, rat; D012260:Ribonucleases