Cineole as skin penetration enhancer.
Cineole is a chief constituent of eucalyptus oil and constitutes almost 80% of this essential oil. A study was conducted on skin penetration enhancing capacity of cineole (1, 8-cineole) towards the permeation of 5 flurouracil in excised rat skin; it caused almost 83 fold increase in drug permeability co-efficient, the mode of action of acceleration may be described by combined process of partition and diffusion.
Saify
Z S
ZS
Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.
Ahsan
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O
Dayo
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A