Surviving glioblastoma for more than 5 years: the patient's perspective.
The authors performed a comprehensive analysis of the functional outcome of 10 patients who had survived 5 years from a diagnosis of glioblastoma. Neurologic deficits were mild in most patients, but neuropsychological testing demonstrated cognitive deficits in all patients. Depression and anxiety were common. Although most patients thought that their social functioning and work ability were impaired, little reduction in overall quality of life was perceived.
Steinbach
J P
JP
Department of General Neurology, Hertie Institute for Clinical Brain Research, Tübingen, Germany. joachim.steinbach@uni-tuebingen.de
Blaicher
H-P
HP
Herrlinger
U
U
Wick
W
W
Nägele
T
T
Meyermann
R
R
Tatagiba
M
M
Bamberg
M
M
Dichgans
J
J
Karnath
H-O
HO
Weller
M
M
D000203:Activities of Daily Living; D000328:Adult; D001007:Anxiety / Q000209:etiology; D001932:Brain Neoplasms / Q000150:complications* / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D003863:Depression / Q000209:etiology; D005260:Female; D005909:Glioblastoma / Q000150:complications* / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology / Q000503:physiopathology; D009483:Neuropsychological Tests; D011788:Quality of Life; D017741:Survivors; D013997:Time Factors; D014937:Work