title: Low-dose dobutamine stress echocardiography to predict reversibility of mitral regurgitation with CABG.
abstract: The optimal management of moderate (grade 2-3+) ischemic mitral regurgitation (MR) in patients undergoing coronary artery bypass grafting (CABG) remains controversial. While CABG alone can reverse regurgitation in some patients with moderate MR, adjunctive mitral repair may be necessary in others. We performed low-dose dobutamine stress echocardiography (DSE) in 60 patients with moderate MR who were about to undergo CABG. Group I, 25 patients who demonstrated reduction in MR during DSE, had CABG alone. Group II, 35 patients in whom MR was unchanged during DSE, had mitral valve repair as well as CABG. MR was reduced postoperatively in both groups (P < 0.0001). Postoperative ejection fraction in Group I (12.2%) improved more than that in Group II (9.3%) (P < 0.01). We conclude that CABG alone may be sufficient to correct moderate MR when MR is reduced during DSE.
authors.affiliation: Day Hospital, Tehran, Islamic Republic of Iran.
authors.forename: Farideh
authors.initials: F
authors.lastname: Roshanali
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Mandegar
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Yousefnia
authors.forename: Farshid
authors.initials: F
authors.lastname: Alaeddini
authors.forename: Samuel
authors.initials: S
authors.lastname: Wann
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D004280:Dobutamine / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D025401:Echocardiography, Stress; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000601:surgery; D011237:Predictive Value of Tests
chemical_list: D004280:Dobutamine