title: Are recombinant gonadotrophins safer, purer and more effective than urinary gonadotrophins?
abstract: Recombinant gonadotrophins have been proposed as the gold standard for current infertility treatment. However, there is little difference between the various available urinary or recombinant gonadotrophins in terms of safety, purity or clinical efficacy. Resources committed to determining an advantage of one gonadotrophin preparation over another would be better spent on research for new treatments.
authors.affiliation: Division of Reproductive Sciences, Department of Obstetrics and Gynecology, Samuel Lunenfeld Research Institute and the University of Toronto, Canada. rfcasper@aol.com
authors.forename: Robert F
authors.initials: RF
authors.lastname: Casper
mesh_terms: D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects / Q000302:isolation & purification / Q000627:therapeutic use*; D006062:Gonadotropins / Q000235:genetics / Q000627:therapeutic use* / Q000652:urine; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D010062:Ovulation Induction / Q000379:methods / Q000592:standards*; D011994:Recombinant Proteins / Q000009:adverse effects / Q000302:isolation & purification / Q000627:therapeutic use
chemical_list: D005300:Fertility Agents, Female; D006062:Gonadotropins; D011994:Recombinant Proteins