[Study of serum levels of homocystein, lipids and their peroxidation products in patients with coronary heart disease].
The subjects of the study were 30 patients with coronary heart disease (19--with stable, and 11--with instable angina), and 15 practically healthy individuals. The study included measurement of the levels of homocysteine (HC), total cholesterol, cholesterol of low-density lipoproteins, cholesterol of high-density lipoproteins, and lipidperoxidation (LP) products (TBA-reactive products), as well as coagulo-fibrinolytic parameters. The study revealed that patients with instable angina had significantly higher levels of HC and TBA-reactive products compared to those with stable angina and healthy controls. HC level correlated with LP processes in CHD patients (r = 0.55). Methionine loading allowed revealing latent hyperhomocysteinemia.
Belaia
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Fedorova
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D000328:Adult; D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood*; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index
D015415:Biomarkers; D008055:Lipids; D006710:Homocysteine