title: Lawsonia intracellularis proliferative enteropathy in a filly.
abstract: Proliferative enteropathy (PE) caused by the obligate intracellular bacterium Lawsonia intracellularis is a disease of high economic impact in swine worldwide. In most other species the disease occurs as a sporadic infection. This paper reports a PE caused by L. intracellularis in a 9-month-old Pura Raza Española filly with a history of profuse diarrhoea. Pathological lesions consisted of a severe proliferative enteritis associated with argyrophilic bacteria in the apical cytoplasm of proliferating crypt epithelium. Characteristic PCR products confirmed the presumptive diagnosis of L. intracellularis infection. To our knowledge this is the first report of PE in a horse in Europe caused by L. intracellularis.
authors.affiliation: Institute of Animal Pathology, Vetsuisse Faculty, 3001 Berne, Switzerland. kuno.wuersch@itpa.unibe.ch
authors.forename: K
authors.initials: K
authors.lastname: Wuersch
authors.forename: D
authors.initials: D
authors.lastname: Huessy
authors.forename: C
authors.initials: C
authors.lastname: Koch
authors.forename: A
authors.initials: A
authors.lastname: Oevermann
mesh_terms: D000818:Animals; D045824:Desulfovibrionaceae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D004751:Enteritis / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D006736:Horses; D007150:Immunohistochemistry / Q000662:veterinary; D020639:Lawsonia Bacteria / Q000302:isolation & purification*; D013557:Switzerland / Q000453:epidemiology