Selective endo and exo iodocyclizations in the synthesis of quinolines and indoles.
[reaction: see text] A simple, efficient method for a divergent synthesis of indoles, quinolines, and quinolinones using a highly selective endo/exo iodocyclization procedure is described.
Hessian
Karl O
KO
Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, Parkville, Australia.
Flynn
Bernard L
BL
D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis*; D015363:Quinolones / Q000138:chemical synthesis; D013237:Stereoisomerism
D007211:Indoles; D011804:Quinolines; D015363:Quinolones; D007455:Iodine