title: Prediction equation of resting energy expenditure in an adult Spanish population of obese adult population.
abstract: OBJECTIVE
  The aim of our study was to evaluate the accuracy of the equations to estimate REE in obese patents and develop a new equation in our obese population.
  
  
  METHODS
  A population of 200 obesity outpatients was analyzed in a prospective way. The following variables were specifically recorded: age, weight, body mass index (BMI), waist circumference, and waist-to-hip ratio. Basal glucose, insulin, and TSH (thyroid-stimulating hormone) were measured. An indirect calorimetry and a tetrapolar electrical bioimpedance were performed. REE measured by indirect calorimetry was compared with REE obtained by prediction equations to obese or nonobese patients.
  
  
  RESULTS
  The mean age was 44.8 +/- 16.81 years and the mean BMI 34.4 +/- 5.3. Indirect calorimetry showed that, as compared to women, men had higher resting energy expenditure (REE) (1,998.1 +/- 432 vs. 1,663.9 +/- 349 kcal/day; p < 0.05) and oxygen consumption (284.6 +/- 67.7 vs. 238.6 +/- 54.3 ml/min; p < 0.05). Correlation analysis among REE obtained by indirect calorimetry and REE predicted by prediction equations showed the next data; Berstein's equation (r = 0.65; p < 0.05), Harris Benedict's equation (r = 0.58; p < 0.05), Owen's equation (r = 0.56; p < 0.05), Ireton's equation (r = 0.58; p < 0.05) and WHO's equation (r = 0.57; p < 0.05). Both the Berstein's and the Ireton's equations overpredicted REE and showed nonsignificant mean differences form measured REE. The Owen's, WHO's, and Harris Benedict's equations underpredicted REE. Our male prediction equation was REE = 58.6 + (6.1 x weight (kg)) + (1,023.7 x height (m)) - (9.5 x age). The female model was REE = 1,272.5 + (9.8 x weight (kg)) - (61.6 x height (m)) - (8.2 x age). Our prediction equations showed a nonsignificant difference with REE measured (-3.7 kcal/day) with a significant correlation coefficient (r = 0.67; p < 0.05).
  
  
  CONCLUSIONS
  Previously developed prediction equations overestimated and underestimated REE measured. WHO equation developed in normal weight individuals provided the closest values. The two new equations (male and female equations) developed in our study had a good accuracy.
authors.affiliation: Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain.
authors.forename: D A
authors.initials: DA
authors.lastname: de Luis
authors.forename: R
authors.initials: R
authors.lastname: Aller
authors.forename: O
authors.initials: O
authors.lastname: Izaola
authors.forename: E
authors.initials: E
authors.lastname: Romero
mesh_terms: D000328:Adult; D001481:Basal Metabolism / Q000502:physiology*; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002153:Calorimetry, Indirect / Q000379:methods; D017097:Electric Impedance; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D009767:Obesity, Morbid / Q000378:metabolism*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012737:Sex Factors; D013030:Spain; D013851:Thinness / Q000378:metabolism