[Neurological complications following haploidentical bone marrow transplantation].
To explore the occurrence patterns of neurological complications following haploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, choices of therapies and prognosis in 10 patients with neurological disorders were summarized. The results showed that complications occurred in 10 out of 74 patients after bone marrow transplantation, which include 3 with encephalorrhagia, 3 infection, 1 epilepsy, 1 Guillian-Barr's syndrome, 1 encephalopathy and 1 schizophrenia. 4 patients died of neurological complications.


CONCLUSIONS
neurological complications commonly occurred in haploidentical bone marrow transplantation, and encephalorrhagia might be the main indication that needs intensive care. Moreover, central nerve system infection and peripheral nerve diseases associated with slow immune reconstitution should have clinical interests.
Wang
Heng-Xiang
HX
Department of Hemotology, General Hospital of Air Force, PLA, Beijing 100036, China. wang-hengxiang123@yahoo.com.cn
Ji
Shu-Quan
SQ
Zhu
Ling
L
Liu
Jing
J
Xue
Mei
M
Ding
Li
L
Duan
Lian-Ning
LN
Yan
Hong-Min
HM
Chen
Hui-Ren
HR
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects* / Q000276:immunology; D002648:Child; D005260:Female; D006648:Histocompatibility; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology; D007938:Leukemia / Q000601:surgery*; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology*