title: [Role of cytokines and pathogen associated molecular pattern receptors in sepsis].
abstract: Sepsis is life-treating state caused by overwhelming inflammatory response to infection accompanied by disregulation of non-specific immunity mechanisms. In this review we discussed influence of Gram-positive and Gram-negative bacterial virulence factors, cytokines as well as pathogen associated molecular pattern receptors (TLR-toll like receptors, peptydoglican recognition proteins, nucleotide binding oligomerization domains, triggering receptor expressed on myeloid cells-1) on the development and course of sepsis.
authors.affiliation: Katedra i Zakład Mikrobiologii Lekarskiej Slaskiej Akademii Medycznej w Katowicach.
authors.forename: Piotr
authors.initials: P
authors.lastname: Kłuciński
authors.forename: Gayane
authors.initials: G
authors.lastname: Martirosian
mesh_terms: D016905:Gram-Negative Bacterial Infections / Q000378:metabolism* / Q000517:prevention & control; D016908:Gram-Positive Bacterial Infections / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D018805:Sepsis / Q000276:immunology* / Q000378:metabolism*; D051193:Toll-Like Receptors / Q000378:metabolism*
chemical_list: D051193:Toll-Like Receptors