title: Succimer therapy for congenital lead poisoning from maternal petrol sniffing.
abstract: An infant, born at 35 weeks' gestation to a woman who sniffed petrol, had a cord blood lead level eight times the accepted limit. Treatment with oral dimercaptosuccinic acid promptly reduced his blood lead levels. To our knowledge, this is the first reported case of congenital lead poisoning secondary to maternal petrol sniffing. We suggest that at-risk pregnancies should be identified, cord blood lead levels tested, and chelation therapy and developmental follow-up offered to affected infants.
authors.affiliation: Paediatrics, Tamworth Base Hospital, PO Box 640, Tamworth, NSW 2340, Australia. Suzanna.Powell@hnehealth.nsw.gov.au
authors.forename: Suzanna T
authors.initials: ST
authors.lastname: Powell
authors.forename: Srinivas
authors.initials: S
authors.lastname: Bolisetty
authors.forename: Gavin R
authors.initials: GR
authors.lastname: Wheaton
mesh_terms: D000328:Adult; D002614:Chelating Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D020264:Lead Poisoning, Nervous System, Childhood / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D010578:Petroleum / Q000009:adverse effects*; D011247:Pregnancy; D011248:Pregnancy Complications; D019966:Substance-Related Disorders / Q000150:complications*; D004113:Succimer / Q000627:therapeutic use*
chemical_list: D002614:Chelating Agents; D010578:Petroleum; D004113:Succimer