[Optimization of treatment of children with acute intestinal infections by application of Russian biological microbial preparations].
The article presents the results of long-term (several years) use of Russian bifido- and lactocontaing probiotics and data on the clinicolaboratory effectiveness of bifidumbacterin forte, probifor, bifidin, bifilis, calcidum, florin forte, acipol and acilact in children with various intestinal infections of known and unknown etiology. The presented results were obtained by studies conducted according to the requirements of The Governmental Program of L. A. Tarasevich State Institute of Standartization and Medical Biological Preparation Control, which included randomization of groups of patients receiving codified preparations or placebo according to their age, nosology, the degree of the process severity, premorbid status, and the time when the treatment was started. Each of the programs included several hundreds of children, receiving probiotics; in which of the programs the studies were multicentered. The courses of treatment with probiotics were short (1 to 2 weeks). No significant adverse effects were observed.
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D000208:Acute Disease; D000293:Adolescent; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D019936:Probiotics / Q000627:therapeutic use*