Enzyme-triggered self-assembly of peptide hydrogels via reversed hydrolysis.
We demonstrate that proteases can be used to selectively trigger the self-assembly of peptide hydrogels via reversed hydrolysis.
Toledano
Sophie
S
School of Materials & Manchester Interdisciplinary Biocentre, The University of Manchester, UK.
Williams
Richard J
RJ
Jayawarna
Vineetha
V
Ulijn
Rein V
RV
D000596:Amino Acids / Q000737:chemistry; D001407:Bacillus / Q000737:chemistry; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry; D005449:Fluorenes / Q000737:chemistry; D020100:Hydrogels / Q000737:chemistry*; D006868:Hydrolysis; D057927:Hydrophobic and Hydrophilic Interactions; D007700:Kinetics; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010447:Peptide Hydrolases / Q000737:chemistry; D013820:Thermolysin / Q000737:chemistry
D000596:Amino Acids; D004151:Dipeptides; D005449:Fluorenes; D020100:Hydrogels; C016456:N(alpha)-fluorenylmethyloxycarbonylamino acids; D009842:Oligopeptides; D010447:Peptide Hydrolases; D013820:Thermolysin