title: Pt(II)- or Au(III)-catalyzed [3+2] cycloaddition of metal-containing azomethine ylides: highly efficient synthesis of the mitosene skeleton.
abstract: [reaction: see text] Only 1-3 mol % of PtCl(2) or AuBr(3) was sufficient to promote generation and [3+2] cycloaddition of transition-metal-containing azomethine ylides derived from N-(o-alkynylphenyl)imines bearing an internal alkyne moiety. A highly efficient method for the preparation of synthetically useful tricyclic indole derivatives having a substituent at the 3-position of the indole nucleus was established by this method.
authors.affiliation: Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kusama
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Miyashita
authors.forename: Jun
authors.initials: J
authors.lastname: Takaya
authors.forename: Nobuharu
authors.initials: N
authors.lastname: Iwasawa