title: Allergic contact dermatitis to thiourea in a neoprene knee brace.
abstract: SUMMARY An elderly woman developed an itchy, weeping, erythematous, papular eruption, confined to the skin under her neoprene knee brace. Allergic contact dermatitis to diethylthiourea and to her neoprene knee brace were diagnosed by positive patch test reactions. Allergic contact dermatitis from thioureas may be underdiagnosed, as they are not tested as part of the standard patch test series. Clinicians are encouraged to consider this diagnosis in patients with reactions to synthetic rubber, especially neoprene.
authors.affiliation: Faculty of Medicine, Monash University, Melbourne, Australia.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Sakata
authors.forename: Jennifer
authors.initials: J
authors.lastname: Cahill
authors.forename: Rosemary
authors.initials: R
authors.lastname: Nixon
mesh_terms: D000368:Aged; D001915:Braces / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007718:Knee Injuries / Q000175:diagnosis / Q000534:rehabilitation; D009387:Neoprene / Q000009:adverse effects* / Q000737:chemistry; D012882:Skin Tests; D013890:Thiourea / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D009387:Neoprene; D013890:Thiourea