title: Use of trafermin to treat a skin ulcer after repair of a deep auricular laceration: a case report.
abstract: We used trafermin (recombinant human basic fibroblast growth factor) to treat a skin ulcer (diameter, 1 cm; depth, 2 mm) that developed after an extremely deep auricular laceration was sutured. Excellent results were obtained after use of trafermin for 2 weeks. To our knowledge, we report the first clinical use of trafermin in a patient with a skin ulcer resulting from auricular trauma. Trafermin may promise to be an effective treatment for skin ulcers.
authors.affiliation: Department of Otolaryngology, Aichi Medical University, Aichi, Japan. tanigawa@aichi-med-u.ac.jp
authors.forename: Tohru
authors.initials: T
authors.lastname: Tanigawa
authors.forename: Meiho
authors.initials: M
authors.lastname: Nakayama
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Nakamura
authors.forename: Shigeru
authors.initials: S
authors.lastname: Inafuku
mesh_terms: D000368:Aged; D004431:Ear, External / Q000293:injuries; D005346:Fibroblast Growth Factors / Q000627:therapeutic use*; D006801:Humans; D022125:Lacerations / Q000601:surgery; D008297:Male; D010446:Peptide Fragments / Q000627:therapeutic use*; D011183:Postoperative Complications; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology
chemical_list: D010446:Peptide Fragments; C114444:trafermin; D005346:Fibroblast Growth Factors