title: Annular lipoatrophy of the ankles.
abstract: Lipoatrophic panniculitis likely represents a group of disorders characterized by an inflammatory panniculitis followed by lipoatrophy. It occurs locally in a variety of settings and has been reported in the literature under various terms, including annular atrophic connective tissue panniculitis of the ankles, annular and semicircular lipoatrophy, abdominal lipoatrophy, and connective tissue panniculitis. Herein, a case of annular lipoatrophy of the ankles is described in a 6-year-old girl with autoimmune thyroid disease. Histologically, a mixed lobular panniculitis with lipophages was present. This pattern resembles that seen in lipoatrophic panniculitis. After a single, acute episode of an inflammatory process with subsequent lipoatrophy, her skin lesions have stabilized for 2 years requiring no treatment.
authors.affiliation: Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
authors.forename: Otobia G
authors.initials: OG
authors.lastname: Dimson
authors.forename: Nancy B
authors.initials: NB
authors.lastname: Esterly
mesh_terms: D000842:Ankle; D001284:Atrophy; D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D009336:Necrosis; D015434:Panniculitis / Q000276:immunology / Q000473:pathology*; D050151:Subcutaneous Fat / Q000276:immunology / Q000473:pathology*; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000276:immunology