title: Cineole as skin penetration enhancer.
abstract: Cineole is a chief constituent of eucalyptus oil and constitutes almost 80% of this essential oil. A study was conducted on skin penetration enhancing capacity of cineole (1, 8-cineole) towards the permeation of 5 flurouracil in excised rat skin; it caused almost 83 fold increase in drug permeability co-efficient, the mode of action of acceleration may be described by combined process of partition and diffusion.
authors.affiliation: Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Saify
authors.forename: O
authors.initials: O
authors.lastname: Ahsan
authors.forename: A
authors.initials: A
authors.lastname: Dayo