A ring-closing yne-carbonyl metathesis of ynamides.
[reaction: see text] An acid-catalyzed ring-closing ynamide-carbonyl metathesis is described here. This hetero RCM methodology is applicable to the construction of carbocycles as well as heterocycles such as chromenes, quinolizidines, indolizidines, and pyrrolizidines.
Kurtz
Kimberly C M
KC
Department of Chemistry, University of Minnesota, Minneapolis, 55455, USA.
Hsung
Richard P
RP
Zhang
Yanshi
Y
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011763:Pyrrolizidine Alkaloids / Q000138:chemical synthesis / Q000737:chemistry
D000577:Amides; D006574:Heterocyclic Compounds, 2-Ring; D011763:Pyrrolizidine Alkaloids