Changes in amplitude-integrated electroencephalography in neonates treated with extracorporeal membrane oxygenation: a pilot study.
Neonates (n = 20) treated with extracorporeal membrane oxygenation were evaluated with serial amplitude-integrated electroencephalography (aEEG). There was no acute change in aEEG during extracorporeal membrane oxygenation cannulation, nor were there lateralizing effects. An abnormal aEEG predicted death or moderate to severe intracranial neuropathology with sensitivity = 1.0, specificity = 0.75, positive predictive value = 0.86, and negative predictive value = 1.0.
Pappas
Athina
A
Neonatal-Perinatal Medicine Department, Wayne State University School of Medicine, Detroit, Michigan, USA. apappas@med.wayne.edu
Shankaran
Seetha
S
Stockmann
Paul T
PT
Bara
Rebecca
R
D020520:Brain Infarction / Q000175:diagnosis / Q000503:physiopathology; D001930:Brain Injuries / Q000175:diagnosis* / Q000503:physiopathology; D004569:Electroencephalography / Q000379:methods*; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000503:physiopathology; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010865:Pilot Projects; D012131:Respiratory Insufficiency / Q000628:therapy*; D012680:Sensitivity and Specificity