title: The fate of systemic blood pressure in patients after effectively stented coarctation.
abstract: OBJECTIVE
  The current study was designed to assess midterm results of stent implantation into the aorta for native and recurrent coarctation (CoA) in children and young adults.
  
  
  RESULTS
  Forty-three patients (native CoA, 8; female, 12) were treated with stent implantation at a median age of 16.8 years (range 7.9-44.8 years). Only stents dilatable to an adult size aorta were implanted. All but two patients with functionally univentricular hearts had arterial hypertension. Exercise tests, 24-h blood pressure, clinical examination, echocardiography, and elective catheterization were used to assess follow-up. The narrowed segment was widened significantly from a median of 8 to 12.4 mm (P < 0.0005). The peak-to-peak gradient between the ascending and the descending aorta was lowered significantly from a median of 22 mmHg to 1 mmHg (P < 0.0005). No major complications occurred. The systolic blood pressure at the right arm was lowered significantly (P < 0.0005) from 144 mmHg before stent implantation to 128 mmHg at the last visit. At a median follow-up of 30 months (3-72 months), 68% of all patients were classified to be normotensive.
  
  
  CONCLUSIONS
  Stent implantation for selected patients with recurrent and native CoA is safe and may effectively reduce the blood pressure gradient across the CoA site. We suggest using only stents dilatable to an adult size aorta. However, arterial hypertension persists in a significant number of the patients. Impaired elastic properties of the aorta may be the cause for this finding.
authors.affiliation: Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Technische Universität, Germany. eicken@dhm.mhn.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Eicken
authors.forename: Ulrike
authors.initials: U
authors.lastname: Pensl
authors.forename: Walter
authors.initials: W
authors.lastname: Sebening
authors.forename: Alfred
authors.initials: A
authors.lastname: Hager
authors.forename: Thomas
authors.initials: T
authors.lastname: Genz
authors.forename: Christian
authors.initials: C
authors.lastname: Schreiber
authors.forename: Dieter
authors.initials: D
authors.lastname: Lang
authors.forename: Harald
authors.initials: H
authors.lastname: Kaemmerer
authors.forename: Raymonde
authors.initials: R
authors.lastname: Busch
authors.forename: John
authors.initials: J
authors.lastname: Hess
mesh_terms: D000293:Adolescent; D000328:Adult; D000800:Angioplasty, Balloon; D001017:Aortic Coarctation / Q000503:physiopathology / Q000628:therapy*; D001794:Blood Pressure / Q000502:physiology; D006328:Cardiac Catheterization / Q000706:statistics & numerical data; D002648:Child; D004868:Equipment Failure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008134:Long-Term Care; D008297:Male; D018709:Statistics, Nonparametric; D015607:Stents