title: [Escalating management of progressive neuropathic cancer pain].
abstract: The management of tumor-related pain, particularly that which is neuropathic in origin, is both difficult and challenging. According to WHO guidelines, opioids are the first-line analgesics in case of severe tumor-related pain syndromes. Some patients receiving continuous opioid therapy rapidly require increase of the opioid dose. In this case it can be necessary to extend the analgesic regime and to either apply interventional procedures or change the opioid or the route of administration. The case presented is remarkable regarding the severity and persistent nature of the patient's pain despite a variety of commonly employed treatments.
authors.affiliation: Klinik für Anästhesiologie, Intensivmedizin, Schmerztherapie und Palliativmedizin, Universitätsklinikum Giessen und Marburg, Giessen. daniel.heinrichs@chiru.med.uni-giessen.de
authors.forename: D
authors.initials: D
authors.lastname: Heinrichs
authors.forename: T
authors.initials: T
authors.lastname: Fritz
authors.forename: H
authors.initials: H
authors.lastname: Otto
authors.forename: K
authors.initials: K
authors.lastname: Diehlmann
authors.forename: R
authors.initials: R
authors.lastname: Matejec
authors.forename: G
authors.initials: G
authors.lastname: Hempelmann
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use*; D018450:Disease Progression; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage / Q000627:therapeutic use*; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy*; D017409:Sufentanil / Q000600:supply & distribution / Q000627:therapeutic use*
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine; D017409:Sufentanil