title: Microsatellite polymorphism in intron 1 of the bovine myostatin gene.
abstract: Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.
authors.affiliation: Laboratorio de Biotecnología Animal I, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro esq. Elías Pińa, Col. Narciso Mendoza, Cd. Reynosa, Tam. C.P. 88710, México.
authors.forename: Xochitl F
authors.initials: XF
authors.lastname: De la Rosa-Reyna
authors.forename: Mario A
authors.initials: MA
authors.lastname: Rodríguez Pérez
authors.forename: Ana M
authors.initials: AM
authors.lastname: Sifuentes-Rincón
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle / Q000145:classification / Q000235:genetics*; D005838:Genotype; D007438:Introns / Q000235:genetics*; D018895:Microsatellite Repeats / Q000235:genetics*; D008969:Molecular Sequence Data; D055435:Myostatin; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D016212:Transforming Growth Factor beta / Q000235:genetics*
chemical_list: C525911:MSTN protein, human; D055435:Myostatin; D016212:Transforming Growth Factor beta