title: Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: a randomized controlled study.
abstract: OBJECTIVE
  To compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children.
  
  
  METHODS
  Forty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n=16) received bupivacaine, group 2 (n=15) received ropivacaine, and a group 3 (control) (n=15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24h postoperatively.
  
  
  RESULTS
  No difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p>0.05). The pain scores in both analgesia groups were significantly (p<0.05) lower 1, 4, 12, 16, and 24h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p<0.05) different between the analgesia and control groups.
  
  
  CONCLUSIONS
  Local ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain.
authors.affiliation: Department of Otolaryngology, Mustafa Kemal University Medical Faculty, Araştirma Hastanesi, 31100 Antakya, Turkey.
authors.forename: Ertap
authors.initials: E
authors.lastname: Akoglu
authors.forename: B Cagla Ozbakis
authors.initials: BC
authors.lastname: Akkurt
authors.forename: Kerem
authors.initials: K
authors.lastname: Inanoglu
authors.forename: Semsettin
authors.initials: S
authors.lastname: Okuyucu
authors.forename: Safak
authors.initials: S
authors.lastname: Dagli
mesh_terms: D000577:Amides / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D000077212:Ropivacaine; D014068:Tonsillectomy; D016896:Treatment Outcome
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D002045:Bupivacaine