title: Evaluation of the protection conferred by a disinfectant against clinical disease caused by Avibacterium paragallinarum serovars A, B, and C from Argentina.
abstract: This work evaluates the efficiency of the administration of the disinfectant N-alkyl dimethyl benzyl ammonium chloride (TIMSEN) in the prevention of the horizontal transmission of serovars A, B, and C of Avibacterium paragallinarum, the causative agent of avian infectious coryza. This disinfectant was administered in drinking water (50 ppm) and once or twice per day by coarse spray (800 ppm, 8 ml per m3 during 3 seconds). In three trials conducted with vaccinated birds, the disinfectant reduced the clinical signs of infectious coryza significantly (P < 0.05). There was no significant effect when the product was used in a fourth trial with unvaccinated birds. Furthermore, the application of only one daily environmental spraying was sufficient to significantly reduce clinical signs. According to these results, in order to diminish the clinical signs of infectious coryza in birds vaccinated against A. paragallinarum, it is recommended to administer this disinfectant in drinking water and by environmental spraying.
authors.affiliation: Instituto Nacional de Tecnologîa Agropecuaria (INTA), Estación Experimental Agropecuaria (EEA) Balcarce, Argentina.
authors.forename: Yosef D
authors.initials: YD
authors.lastname: Huberman
authors.forename: Dante J
authors.initials: DJ
authors.lastname: Bueno
authors.forename: Horacio R
authors.initials: HR
authors.lastname: Terzolo
mesh_terms: D000336:Aerosols; D000818:Animals; D001548:Benzalkonium Compounds / Q000008:administration & dosage; D002645:Chickens / Q000382:microbiology*; D004202:Disinfectants / Q000008:administration & dosage*; D006192:Haemophilus Infections / Q000382:microbiology / Q000517:prevention & control / Q000635:transmission / Q000662:veterinary*; D044134:Haemophilus paragallinarum / Q000145:classification; D011201:Poultry Diseases / Q000382:microbiology / Q000517:prevention & control* / Q000635:transmission; D012703:Serotyping; D014881:Water Supply
chemical_list: D000336:Aerosols; D001548:Benzalkonium Compounds; D004202:Disinfectants