Removal of a residual portion of a uterine septum in women of advanced reproductive age: obstetric outcome.
BACKGROUND
To learn more about the obstetric outcome after initial septum resection and remnant septum (< or =1 cm) resection.


METHODS
In 94 patients with septate uteri who underwent uterine septum resection, the reproductive efficiency was analysed in a prospective observational study. The reproductive outcome was analysed after initial resection and (if required) consecutive procedures.


RESULTS
A total of 94 women were enrolled in the study; all had had two or more miscarriages. The septum was completely removed during the first hysteroscopy in 58 (62%) cases. A residual septum was observed in 36 (38%) patients. Subsequent operative hysteroscopy was performed in the cases (29/36; 80.5%) involving repeated miscarriage and unsuccessful conception. The minimum observation time was 24 months. The difference in delivery rate after the first hysteroscopy between those with a normalized uterine cavity (26/58; 44.8%) and those with remnants (7/36; 19.4%) was statistically significant (P < 0.05). In fact, following the normalization of the uterine cavity, 62.1% (18/29) of the patients delivered, as compared with 19.4% of those (7/36) with a residue and Kaplan-Meyer curves revealed a statistically significant difference (P < 0.05).


CONCLUSIONS
Women with a remnant uterine septum have an increased chance of successful pregnancy with an improved obstetric outcome after normalization of the uterine cavity.
Kormányos
Zsolt
Z
Department of Obstetrics and Gynaecology, Faculty of General Medicine, Albert Szent-Györgyi Medical and Pharmacological Centre, University of Szeged, Szeged, Hungary. kormanyos@obgyn.szote.u-szeged.hu
Molnár
Béla G
BG
Pál
Attila
A
D000022:Abortion, Spontaneous; D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000601:surgery*; D008423:Maternal Age; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000002:abnormalities / Q000473:pathology / Q000601:surgery*