Gene-hypermutated isoforms of MYC protein: Tumour-suppressor P-53 protective-initiation of apoptosis that normally prevents Burkitt's lymphoma tumorigenesis can be enhanced.
Wiseman
Alan
A
D000818:Animals; D017209:Apoptosis; D002051:Burkitt Lymphoma / Q000235:genetics / Q000378:metabolism*; D049109:Cell Proliferation; D006801:Humans; D008954:Models, Biological; D009154:Mutation; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism*; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*
C489427:MYC protein, human; D009363:Neoplasm Proteins; D020033:Protein Isoforms; D016271:Proto-Oncogene Proteins c-myc; D016159:Tumor Suppressor Protein p53