[Influence of cell therapy and alimentary correction on the condition of microcirculatory system in experimental dyslipidemia].
A comparative analysis of the impact of cell therapy (allogenic fetal liver cells, stem cells of autologic bone marrow) on lipid homeostasis, microcirculatory disturbances and structural changes in some organs was made using the atherosclerosis model in guinea-pigs. A positive effect of cell therapy on these parameters was established. The effect was stronger and prolonged after transplantation of stem cells. Atherogenic diet weakens the effect of cell therapy. Thus, cell therapy is more effective in restriction of atherogenic risk factors.
Kobozeva
L P
LP
Michunskaia
A B
AB
Kulikova
O S
OS
Bersenev
A V
AV
Klimenko
E D
ED
Onishchenko
N A
NA
Pozdniakov
O M
OM
D000818:Animals; D050197:Atherosclerosis / Q000473:pathology / Q000628:therapy; D016026:Bone Marrow Transplantation / Q000379:methods*; D017690:Cell Transplantation / Q000379:methods*; D004036:Diet, Atherogenic; D050171:Dyslipidemias / Q000473:pathology / Q000628:therapy*; D006168:Guinea Pigs; D008099:Liver / Q000196:embryology / Q000473:pathology; D008297:Male; D008833:Microcirculation