[Schilddrüse und polyendokrinopathien].
The thyroid gland can be affected in the course of several polyendocrinopathy syndromes either by impairment of physiological function or thyroid carcinoma. The various syndromes -- polyglandular autoimmune syndrome, autoimmune hypophysitis, multiple pituitary hormone deficiency, multiple endocrine neoplasia, and Carney complex -- are discussed. Therapy of thyroid dysfunction is identical whether it is part of a specific syndrome or not. Genetic testing for mutations, however, has had an enormous impact on screening procedures and therapeutic consequences.
Luger
Anton
A
Klinische Abteilung für Endokrinologie und Stoffwechsel, Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Wien, Austria. anton.luger@meduniwien.ac.at
D002869:Chromosome Aberrations; D005808:Genes, Recessive; D005820:Genetic Testing; D006801:Humans; D016884:Polyendocrinopathies, Autoimmune / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy; D013959:Thyroid Diseases / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy; D013961:Thyroid Gland / Q000503:physiopathology; D013964:Thyroid Neoplasms / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy