title: Stability of estimated IQ across mood state in patients with bipolar disorder.
abstract: OBJECTIVE
  The goal of this study was to assess the impact of mania symptoms on the stability of the American version of the National Adult Reading Test (ANART), a measure that provides a putative estimate of premorbid intellectual functioning.
  
  
  METHODS
  The ANART was administered to a sample of 10 inpatients with bipolar disorder who were experiencing an acute episode of mania. During a subsequent follow-up visit during which these individuals exhibited at most minimal mood symptoms, the ANART was re-administered.
  
  
  RESULTS
  ANART estimated intelligence quotient (IQ) scores during mania and affective stability were assessed in the 10 patients using a paired sample t-test. Within-subject performance across the two mood states did not significantly differ [t(9) = -1.24, p = 0.25]. Additionally, the greatest individual difference across mood states was only 3.68 points, and the average estimated IQ difference across mood states was 1.66.
  
  
  CONCLUSIONS
  While the results are preliminary and based on a small sample, the highly consistent scores achieved across mood states in this study suggest that the ANART is a reliable indicator of premorbid IQ.
authors.affiliation: Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45221-0376, USA.
authors.forename: Brian K
authors.initials: BK
authors.lastname: Lebowitz
authors.forename: Paula K
authors.initials: PK
authors.lastname: Shear
authors.forename: Marc A
authors.initials: MA
authors.lastname: Steed
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Strakowski
mesh_terms: D000208:Acute Disease; D000328:Adult; D000339:Affect; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007206:Individuality; D007360:Intelligence; D007361:Intelligence Tests / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D011594:Psychometrics / Q000706:statistics & numerical data; D011932:Reading; D015203:Reproducibility of Results