A study of the photostability of ergocalciferol (vitamin d(2)) in organic solvents.
The photolysis of ergocalciferol (vitamin D(2)) in several organic solvents has been studied to determine the influence of solvent dielectric constant and viscosity on the rate of reaction. Ergocalciferol degrades by zero-order kinetics and the rate constants vary from 0.74x10(-5) mol 1(-1) (methanol) to 1.56x10(-5) mol 1(-1) (chloroform). The rates appear to be a linear function of the reciprocal of dielectric constant and viscosity of the medium in the range studied.
Ahmad
T
T
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
Ahmad
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I
Majeed
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A