Primary pulmonary mucosa-associated lymphoid tissue lymphoma combined with idiopathic thrombocytopenic purpura and amyloidoma in the lung.
Three abnormal shadows were detected in the right lung on chest X-ray films and computed tomography in a 75-year-old woman during follow-up for idiopathic thrombocytopenic purpura. Because a definitive diagnosis was not obtained through general examinations, exploratory thoracotomy was performed for diagnosis and treatment. The main lesion in the right middle lobe was diagnosed as mucosa-associated lymphoid tissue (MALT) lymphoma according to histopathological findings, cytogenic studies and reverse transcriptase-polymerase chain reaction analysis, and nodular lesions in S(3) and S(7) were diagnosed with Congo-red staining as local deposition of amyloid. The patient had no recurrence of the MALT lymphoma of the lung or other organs for 4 years after surgery. To our knowledge, this is the first reported case of primary pulmonary MALT lymphoma combined with idiopathic thrombocytopenic purpura/lung amyloidoma.
Kawashima
Tetsuo
T
Division of Thoracic Surgery, Department of Surgery, Nippon Medical School, Tokyo, Japan. tkawa@nms.ac.jp
Nishimura
Hitoshi
H
Akiyama
Hirohiko
H
Hirai
Kyoji
K
Yamagishi
Shigeki
S
Okada
Daisuke
D
Kinoshita
Hiroyasu
H
Enomoto
Yutaka
Y
Okamoto
Junichi
J
Nakajima
Yuki
Y
Takeuchi
Shingo
S
Iijima
Yoshihito
Y
Furuhata
Ken
K
Nakayama
Keisuke
K
Izumo
Toshiyuki
T
Koizumi
Kiyoshi
K
Shimizu
Kazuo
K
D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000473:pathology; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed