title: [Epidural analgesia and the course of delivery in term primiparas].
abstract: OBJECTIVE
  Epidural analgesia provides the most effective pain control during labor. Of great concern is its influence on the course of delivery and perinatal complications.
  
  
  METHODS
  The aim of the study was to assess the effect of epidural analgesia on the course of delivery and perinatal outcome.
  
  
  METHODS
  609 deliveries among 1334 (323 women with epidural analgesia (53%) and 548 without epidural analgesia (47%)) met the following criteria: primipara, singleton, live pregnancy, > =37 weeks' gestation, cephalic presentation of a fetus, lack of contraindication for vaginal delivery. The incidence of instrumental deliveries and fetal distress, duration of the first, second and third stage of labor, perinatal outcome, perinatal complications and perinatal blood loss and were analyzed.
  
  
  RESULTS
  The incidence of fetal distress during second stage of labor was significantly higher in the epidural group (12.69 vs. 6.99%, P=0.02). The incidence of fetal distress during first stage of labor did not differ in both groups (10.53% vs. 8.74%, NS). Cesarean sections rate was similar in epidural and non-epidural group (17.7 vs. 18.2%, NS). Among vaginal deliveries duration of the first and second stage of labor was longer in epidural group (6.5+/-2.4 vs. 5.4+/-2.5 godz., P=0,000003 and 47.3+/-34.8 vs. 29.1+/-25.8 min., P=0.000003) and this was independent of period of time between onset of first stage of labor and epidural analgesia. Oxitocin use was significantly more frequent in the epidural group (20.6 vs. 10.3%, P<0.004). There were no statistically significant differences in the rates of instrumental vaginal deliveries, 1 and 5-minute Apgar scores, length of third stage of labor and perinatal blood loss in patients with and without epidural analgesia. Perinatal outcome did not depend on previous use of epidural analgesia or mode of analgesia for the operation in cesarean section subgroup.
  
  
  CONCLUSIONS
  Epidural labor analgesia is associated with slower progress of labor but has no adverse effect on perinatal outcome and perinatal complications.
authors.affiliation: II Katedra i Klinika Połoznictwa i Ginekologii Akademii Medycznej w Warszawie.
authors.forename: Jacek
authors.initials: J
authors.lastname: Sieńko
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Czajkowski
authors.forename: Magdalena
authors.initials: M
authors.lastname: Swiatek-Zdzienicka
authors.forename: Romana
authors.initials: R
authors.lastname: Krawczyńska-Wichrzycka
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000779:Anesthetics, Local / Q000008:administration & dosage*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D048949:Labor Pain / Q000188:drug therapy*; D007747:Labor Stage, First / Q000187:drug effects; D007748:Labor Stage, Second / Q000187:drug effects; D007743:Labor, Obstetric / Q000187:drug effects*; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: D000779:Anesthetics, Local