Linear basal cell carcinoma: a distinct clinical entity in the periocular region.
OBJECTIVE
To report periocular linear basal cell carcinoma (BCC) as a distinct clinical entity, and to highlight its existence in the ophthalmic literature.


METHODS
Retrospective, noncomparative, multicenter, interventional small case series.


METHODS
Four patients with linear BCC in the periocular region.


METHODS
All patients underwent margin-controlled excision, 3 utilizing Mohs' micrographic surgery and 1 using frozen section.


METHODS
Age, gender, location, preoperative tumor size, histological growth pattern, presence of perineural invasion, number of Mohs' levels used to obtain histologic clearance, postoperative defect size, and recurrence.


RESULTS
In all 4 cases, the site of occurrence was in the lower eyelid and cheek. Histology revealed pigmented nodular BCC with an infiltrative component in 2 cases and nodular BCC in the remaining 2 cases. No perineural invasion was noted in any of the cases. Two Mohs' levels were required for complete excision in 3 patients.


CONCLUSIONS
Linear BCC is a distinct clinical entity. Presence of the tumor along relaxing skin tension lines, increase in subclinical extension, and aggressive tumor behavior are reported observations. Because of these observations, it is suggested that margin-controlled excision should be considered for linear BCC.
Mavrikakis
Ioannis
I
Corneoplastic Unit & Eye Bank, Queen Victoria Hospital NHS Trust, East Grinstead, United Kingdom.
Malhotra
Raman
R
Barlow
Richard
R
Huilgol
Shyamala C
SC
Selva
Dinesh
D
D000368:Aged; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery