title: Real-time transthoracic three-dimensional echocardiographic assessment of left ventricular volume and ejection fraction in congenital heart disease.
abstract: OBJECTIVE
  The purpose of this study was to assess the (1) feasibility of real-time three-dimensional echocardiography (RT-3DE) data acquisition and (2) volumes and function of the abnormal left ventricle (LV) in adult patients with congenital heart disease (CHD), compared with magnetic resonance imaging (MRI) data.
  
  
  METHODS
  Thirty-two patients (59% were male) with CHD were evaluated on the same day by MRI and RT-3DE. Acquisition of RT-3DE data sets was feasible in 29 of the 32 patients (91%). The time of 3D data acquisition was 4 +/- 2 minutes, and LV analysis was 17 +/- 5 minutes per patient for manual border tracing.
  
  
  RESULTS
  A good correlation was observed between RT-3DE with manual border detection and MRI for LV end-diastolic volume (r = 0.97), LV end-systolic volume (r = 0.98), and LV ejection fraction (r = 0.94).
  
  
  CONCLUSIONS
  RT-3DE is feasible for volumetric analysis of the abnormal LV allowing accurate determination of LV volume and ejection fraction compared with MRI in adult patients with CHD.
authors.affiliation: Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands.
authors.forename: Annemien E
authors.initials: AE
authors.lastname: van den Bosch
authors.forename: Danielle
authors.initials: D
authors.lastname: Robbers-Visser
authors.forename: Boudewijn J
authors.initials: BJ
authors.lastname: Krenning
authors.forename: Marco M
authors.initials: MM
authors.lastname: Voormolen
authors.forename: Jackie S
authors.initials: JS
authors.lastname: McGhie
authors.forename: Wim A
authors.initials: WA
authors.lastname: Helbing
authors.forename: Jolien W
authors.initials: JW
authors.lastname: Roos-Hesselink
authors.forename: Maarten L
authors.initials: ML
authors.lastname: Simoons
authors.forename: Folkert J
authors.initials: FJ
authors.lastname: Meijboom
mesh_terms: D000328:Adult; D003199:Computer Systems; D004452:Echocardiography / Q000379:methods; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005240:Feasibility Studies; D006330:Heart Defects, Congenital / Q000150:complications / Q000000981:diagnostic imaging*; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology