title: Perfusion MR imaging of an intracranial collision tumor confirmed by image-guided biopsy.
abstract: We present a patient with a new intracranial mass lesion that was initially interpreted as a metastasis on conventional anatomic MR imaging. On dynamic, contrast-enhanced, susceptibility-weighted perfusion MR imaging, however, there were regional hemodynamic differences within the lesion. Image-guided open biopsy targeting these regions uncovered a collision tumor between a typical meningioma and a metastatic breast carcinoma. In cases where conventional anatomic MR imaging is ambiguous, physiology-based neuroimaging methods provide complementary physiologic information useful for discriminating between histologically unique tissue types.
authors.affiliation: Department of Radiology, University of California, San Francisco, CA 94143, USA.
authors.forename: P
authors.initials: P
authors.lastname: Jun
authors.forename: J
authors.initials: J
authors.lastname: Garcia
authors.forename: T
authors.initials: T
authors.lastname: Tihan
authors.forename: M W
authors.initials: MW
authors.lastname: McDermott
authors.forename: S
authors.initials: S
authors.lastname: Cha
mesh_terms: D001706:Biopsy; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*
chemical_list: D003287:Contrast Media