title: Decreased regurgitation with a soy formula containing added soy fiber.
abstract: The objective of this randomized study was to determine if fiber-supplemented soy formula reduced regurgitation in young infants. We compared regurgitation in 179 infants randomly assigned cow's milk-based (CM, 90) formula or soy formula with fiber (SF, 89). Initial daily incidence was similar (CM, 3.6; SF, 3.9 episodes), but significantly lower after 7 days on SF (CM, 3.4; SF, 2.3; p = 0.001). Less frequent regurgitation after 7 days on SF was sustained after 28 days (CM, 48%; SF, 31% of feedings; p = 0.001). Feeding SF effectively managed regurgitation while providing balanced nutrition without altering caloric distribution as occurs with adding rice cereal to formula.
authors.affiliation: Ross Products Division, Abbott Laboratories, Columbus, OH 43215-1724, USA.
authors.forename: Karin M
authors.initials: KM
authors.lastname: Ostrom
authors.forename: Joan R
authors.initials: JR
authors.lastname: Jacobs
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Merritt
authors.forename: Robert D
authors.initials: RD
authors.lastname: Murray
mesh_terms: D000818:Animals; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D041943:Infant Formula / Q000008:administration & dosage*; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D008297:Male; D008892:Milk; D011336:Probability; D012016:Reference Values; D018570:Risk Assessment; D041942:Soy Milk / Q000008:administration & dosage*