Toward high-throughput drug screening using mass spectrometry.
A critical overview on the potential of mass spectrometry-based methods regarding high-throughput screening analysis is presented. Within this scope, screening procedures will be discussed for simultaneous detection of several drug classes relevant to clinical and forensic toxicology or doping control in urine or blood using gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry.
Maurer
Hans H
HH
Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, University of Saarland, Homburg, Saar, Germany. hans.maurer@uniklinikum-saarland.de
Peters
Frank T
FT
D004353:Drug Evaluation, Preclinical / Q000379:methods* / Q000639:trends; D013287:Illicit Drugs / Q000032:analysis; D013058:Mass Spectrometry / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000032:analysis
D013287:Illicit Drugs; D004364:Pharmaceutical Preparations