[Hydration of patients treated with cisplatin: practical investigation and establishment of a protocol].
BACKGROUND
Administration of cisplatin requires hyperhydration of the patient to prevent nephrotoxic effects of this molecule.


METHODS
A survey done in different hospitals - university hospitals, general hospitals and cancer institutes--has shown a large variability in the hydration protocols. A multidisciplinary group was set up in our university hospital comprising oncologists, nephrologists and pharmacists. This group has developed a consensual local protocol from a bibliographic analysis (Medline) and from the personal experience of each member.


CONCLUSIONS
This protocol was approved by our hospital's Committee of Drugs and Medical Devices.
Saint-Lorant
Guillaume
G
Pharmacie Centrale, CHU de Caen, Caen, France. guillaume.saint-lorant@wanadoo.fr
Madelaine
Jeannick
J
Galais
Marie-Pierre
MP
Thierry
Lobbedez
L
Chédru-Legros
Valérie
V
D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D012996:Solutions
D012996:Solutions; D002945:Cisplatin