Synthesis and antimicrobial activities of 1, 2-di (6-methylquinolyl-2) 1, 2-ethanedion.
The 1,2-di(6-methylquinolyl-2)-1,2-ethanedion is obtained when 1,2-di(6-methylquinolyl-2)-1,2-ethenediol was oxidized using air as an oxidizing agent whereas the starting material itself was synthesized when 6-methyl quinoline-2-carboxaldehyde was subjected to condensation reaction in the presence of potassium cyanide. The biological screening of the resulting substituted 1,2-diketone revealed its significant antimicrobial activities.
Ansar
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Department of Chemistry, Adamjee Government Science College, Karachi, Pakistan.
Nizami
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