Stem cell transplantation for the treatment of myocardial infarction.
Stem cell transplantation provides a potential regenerative therapy for the heart damaged by myocardial infarction. Numerous scientific studies have been undertaken in animals and humans to analyze the safety and efficacy of this new approach. However, at the present time, the results have been mixed and inconclusive, and the mechanism of stem cell transplantation therapy remains unclear. This review discusses the controversies and problems that need to be addressed in future investigations.
Dai
Wangde
W
The Heart Institute, Good Samaritan Hospital, Division of Cardiovascular Medicine of the Keck School of Medicine at University of Southern California, 1225 Wilshire Boulevard, Los Angeles, CA 90017-2395, USA.
Hale
Sharon L
SL
Kloner
Robert A
RA
D000818:Animals; D018421:Cardiomyoplasty / Q000379:methods / Q000639:trends; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods* / Q000639:trends