title: A resin-modified glass ionomer cement barrier for treating degree II furcation defects: a pilot study in dogs.
abstract: OBJECTIVE
  The aim of this study was to evaluate in an animal model the healing of degree II furcation defects treated with: an experimental barrier of resin-modified glass-ionomer cement (GIC), a polylactic acid barrier (GUI), and flap surgery (CTR).
  
  
  METHODS
  In 3 beagles, 18 class II furcation defects were surgically produced in mandibular and maxillary premolars and exposed to plaque accumulation for 21 days. Following a full flap, notches were made at the base to the bone defect. GIC barriers were prepared immediately before use from a commercial product and fit to place with the same product. The GIC barriers were removed after 30 days and the dogs euthanized after 120 days. Histologic sections were analyzed in a computer-assisted microscope. Epithelium, new cementum with inserting fibers, and connective tissue lining the root surface in-between notches were measured and medians of percentage values calculated.
  
  
  RESULTS
  In the GIC, epithelium constituted 3.5% (median values) of the notch-to-notch root area; new cementum was 83.6% and connective tissue 12.9%. These values were 0%, 73.6%, and 26.4% for the GUI group and 35.6%, 43.2%, and 0% for the CTR group. Bone fill median values were 54.3% for GIC, 20.6% for GUI, and 24.6% for CTR.
  
  
  CONCLUSIONS
  GIC and GUI prevented epithelial migration and promoted the formation of new periodontal tissues in experimentally induced class II furcation defects in dogs.
authors.affiliation: Graduate Programme in Periodontology, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. Leticia.Miranda@ofa.ki.se
authors.forename: Letícia Algarves
authors.initials: LA
authors.lastname: Miranda
authors.forename: Sabrina Carvalho
authors.initials: SC
authors.lastname: Gomes
authors.forename: Ilson José
authors.initials: IJ
authors.lastname: Soares
authors.forename: Rui Vicente
authors.initials: RV
authors.lastname: Oppermann
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D002951:Citrates; D003238:Connective Tissue / Q000502:physiology; D003739:Dental Cementum / Q000502:physiology; D004285:Dogs; D004848:Epithelium / Q000502:physiology; D005260:Female; D017823:Furcation Defects / Q000601:surgery*; D005899:Glass Ionomer Cements; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation*; D008567:Membranes, Artificial; D010865:Pilot Projects; D011091:Polyesters
chemical_list: D001672:Biocompatible Materials; D002951:Citrates; D005899:Glass Ionomer Cements; C105021:Guidor; D008567:Membranes, Artificial; D011091:Polyesters