Acremonium kiliense infection in a child with chronic granulomatous disease.
Infection by unusual microorganisms can be one of the clinical manifestations of primary immunodeficiency (PID). We report on a four-month-old child with pneumonia caused by the fungus Acremonium kiliense as the first clinical manifestation of chronic granulomatous disease. We emphasize the importance of an active search for unusual organisms in immunodeficient patients, and a precise diagnosis and early institution of specific treatment against such microorganisms for the reduction of the morbidity and mortality of these patients.
Pastorino
Antonio Carlos
AC
Allergy and Immunology Unit, Department of Pediatrics, University of São Paulo, São Paulo, SP, Brazil. antoniocp@icr.hcnet.usp.br
Menezes
Ulissis Pádua de
UP
Marques
Heloisa Helena de Souza
HH
Vallada
Marcelo G
MG
Cappellozi
Vera Lúcia
VL
Carnide
Eugénia Maria Grilo
EM
Jacob
Cristina Miuki Abe
CM
D000164:Acremonium / Q000302:isolation & purification*; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007223:Infant; D008297:Male; D009181:Mycoses / Q000175:diagnosis / Q000382:microbiology*; D009894:Opportunistic Infections / Q000150:complications / Q000175:diagnosis / Q000382:microbiology*; D011014:Pneumonia / Q000150:complications / Q000175:diagnosis / Q000382:microbiology*