Autoimmune myasthenia gravis after coronary artery bypass surgery.
Myasthenia gravis is the most common disorder of neuromuscular transmission and is a heterogeneous disorder that is generally autoimmune, which is caused by an auto-antibody to the nicotinic acetylcholine receptor. We present a rare case of myasthenia gravis that occurred 8 weeks after a coronary artery bypass grafting operation. A 64-year-old man with multivessel coronary artery disease underwent myocardial revascularization. Severe myasthenic symptoms began 8 weeks after the operation and emergent mechanical ventilation was needed because of myasthenic crises. The serum anti-acetylcholine receptor antibody level was high. The details of this unusual patient are discussed.
Resatoglu
Adem Gýrbolar
AG
Department of Cardiovascular Surgery, Cankaya Hospital, Ankara, Turkey.
Tok
Mustafa
M
Yemisci
Muge
M
Yener
Nuran
N
Yener
Ali
A
D000917:Antibody Formation; D001327:Autoimmune Diseases / Q000209:etiology* / Q000473:pathology; D001026:Coronary Artery Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000209:etiology* / Q000473:pathology; D011183:Postoperative Complications; D011950:Receptors, Cholinergic / Q000276:immunology; D012121:Respiration, Artificial; D013997:Time Factors
D011950:Receptors, Cholinergic