title: [Histomorphometric evaluation of bone ingrowth of porous titanium by a computer-assisted analyzing system].
abstract: The objective of this study was to evaluate the bone ingrowth of a new vacuum plasma sprayed titanium surface (vps-ti) in comparison to cs-titanium implants in a göttinger minipig model. Fifteen göttinger minipigs each received the two implants, vacuum plasma sprayed titanium with a porosity of 50% and a pore size of 200 microm (vps-ti) and an implant with a similar porosity but a different pore size 500 microm (cs-ti), at the proximal femur metaphysis by press-fit technique. The pigs were euthanized at three different postsurgical periods: 4, 8 and 12 weeks. Each femur was harvested and qualitative (macroscopic and microscopic) and quantitative (histomorphometric) histological analysis was done on histological slides. The results indicated that there was a difference in bone ingrowth between the two implants, whereas the bone ingrowth of vps-ti was superior to cs-ti after 4 and 8 weeks healing time. 12 weeks post implantationem no statistiscal difference was evident. The pore size of 200 microm seemed superior to a pore size of 500 microm. Whether or not these effects lead to a better mechanical stability remains unanswered.
authors.affiliation: Labor für experimentelle Orthopädie und Biomechanik der Philipps-Universität Marburg. endres@med.uni-marburg.de
authors.forename: S
authors.initials: S
authors.lastname: Endres
authors.forename: M
authors.initials: M
authors.lastname: Wilke
authors.forename: H
authors.initials: H
authors.lastname: Frank
authors.forename: P
authors.initials: P
authors.lastname: Knöll
authors.forename: M
authors.initials: M
authors.lastname: Kratz
authors.forename: M
authors.initials: M
authors.lastname: Windler
authors.forename: A
authors.initials: A
authors.lastname: Wilke
mesh_terms: D000818:Animals; D019544:Equipment Failure Analysis / Q000379:methods*; D005269:Femur / Q000166:cytology* / Q000502:physiology* / Q000601:surgery; D006622:Hip Prosthesis; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008422:Materials Testing / Q000379:methods; D016348:Osseointegration / Q000502:physiology*; D016062:Porosity; D013552:Swine; D013556:Swine, Miniature; D014025:Titanium / Q000032:analysis / Q000737:chemistry*
chemical_list: D014025:Titanium