Physical anhedonia in the acute phase of schizophrenia.
BACKGROUND
The aim of the current study is to investigate the relationship between physical anhedonia and psychopathological parameters, pharmacological parameters or motor side-effects in a sample of inpatients with schizophrenia in an acute episode of their illness.


METHODS
Eighty one patients with schizophrenia, consecutively admitted, with an acute episode of their illness, at the Eginition Hospital, Department of Psychiatry, University of Athens, during a one-year period were investigated regarding possible relationships between physical anhedonia, social-demographic data and clinical parameters as well as motor side-effects, induced by antipsychotic agents. All patients were assessed using the Chapman Revised Physical Anhedonia Scale (RPAS), the Positive and Negative Syndrome Scale (PANSS), the Rating Scale for Extrapyramidal Side-Effects (EPSE), the Barnes Akathisia Rating Scale (BARS) and the Abnormal Involuntary Movement Scale (AIMS). Simple cross tabulations were initially employed. Subsequently, multiple regression analysis was performed.


RESULTS
Both positive and negative symptoms were associated with physical anhedonia. A positive association between physical anhedonia and the non-paranoid sub-category of schizophrenia was also proved.


CONCLUSIONS
According to these results, it seems that in the acute phase of schizophrenia, physical anhedonia may be a contributing factor to patient's psychopathology.
Kontaxakis
Vassilis P
VP
Department of Psychiatry, University of Athens, Eginition Hospital, 74 Vas, Sophias Ave, 11528 Athens, Greece. bkont@cc.uoa.gr
Kollias
Costas T
CT
Havaki-Kontaxaki
Beata J
BJ
Margariti
Maria M
MM
Stamouli
Sophia S
SS
Petridou
Eleni
E
Christodoulou
George N
GN