title: [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].
abstract: A 23-year-old woman experienced generalized urticaria and loss of consciousness during walking after ingestion of wheat. Skin prick test and CAP-RAST were positive for gluten. An oral challenge test using 100g wheat was positive without exercise. The patient was given diagnosis of wheat allergy. In addition, not only exercise but also administration of 500mg aspirin were found to exacerbate her symptoms after the ingestion of wheat, suggesting that acetylsalicylic acid could be an augmentation factor in wheat allergy. Etodorac failed to enhance the symptoms. Further, oral administration of Fexofenadine could prevent allergic reactions induced by ingestion of 100g wheat, but sodium cromoglycate partially reduced the reactions.
authors.affiliation: Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan. fuji_fuji_fuji_0101@yahoo.co.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujita
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osuna
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kanbara
authors.forename: Naoko
authors.initials: N
authors.lastname: Inomata
authors.forename: Zenro
authors.initials: Z
authors.lastname: Ikezawa
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001241:Aspirin / Q000009:adverse effects*; D004205:Cromolyn Sodium / Q000008:administration & dosage; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D011852:Radioallergosorbent Test; D012882:Skin Tests; D016593:Terfenadine / Q000008:administration & dosage / Q000031:analogs & derivatives; D021182:Wheat Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control
chemical_list: D016593:Terfenadine; C093230:fexofenadine; D004205:Cromolyn Sodium; D001241:Aspirin