title: The regulation of appetite.
abstract: The worsening global obesity epidemic, particularly the increase in childhood obesity, has prompted research into the mechanisms of appetite regulation. Complex pathways modulate energy balance, involving appetite centres in the hypothalamus and brain stem, and hormonal signals of energy status released by the gut and by the periphery. Better understanding of appetite regulation improves understanding of the aetiology of obesity. Manipulation of this homoeostatic system offers potentially useful treatments for obesity.
authors.affiliation: Department of Metabolic Medicine, Imperial College London, 6th Floor, Commonwealth Building, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
authors.forename: M
authors.initials: M
authors.lastname: Druce
authors.forename: S R
authors.initials: SR
authors.lastname: Bloom
mesh_terms: D000328:Adult; D000818:Animals; D001069:Appetite Regulation / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D004734:Energy Metabolism / Q000502:physiology; D005768:Gastrointestinal Hormones / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D006728:Hormones / Q000502:physiology; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D009765:Obesity / Q000503:physiopathology* / Q000628:therapy; D012527:Satiation / Q000502:physiology
chemical_list: D005768:Gastrointestinal Hormones; D006728:Hormones