title: 2005 update on pathology of prostate biopsies with cancer.
abstract: OBJECTIVE
  To review the diagnostic and prognostic importance of pathologic findings in prostate biopsies.
  
  
  RESULTS
  While the primary goal of the biopsy is to diagnose prostatic adenocarcinoma, once carcinoma is detected, information regarding the type, amount, and grade of cancer forms the cornerstone for contemporary management of the patient and for assessment of the potential for local cure and the risk for distant metastasis.
  
  
  CONCLUSIONS
  The novelty of this 2005 update is represented by a detailed morphologic and immunohistochemical description of prostatic adenocarcinoma features in biopsies.
authors.affiliation: Pathology, Polytechnic University, Ancona, Italy. r.montironi@univpm.it
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.forename: Remigio
authors.initials: R
authors.lastname: Vela-Navarrete
authors.forename: Antonio
authors.initials: A
authors.lastname: Lopez-Beltran
authors.forename: Roberta
authors.initials: R
authors.lastname: Mazzucchelli
authors.forename: Aldo
authors.initials: A
authors.lastname: Bono
mesh_terms: D044963:Biopsy, Fine-Needle / Q000639:trends*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009361:Neoplasm Invasiveness; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D013194:Staining and Labeling
chemical_list: D017430:Prostate-Specific Antigen