[Primary eosinophilic esophagitis].
Primary eosinophilic esophagitis (EE) is a rare disease with symptoms similar to those of gastroesophageal reflux disease (GERD). However, EE is caused by severe eosinophilic invasion of the esophageal epithelium, typically followed by dysphagia. A man 28 years of age presented persistent symptoms of GERD despite traditional antireflux therapy. Histologic evaluation showed eosinophilia (85 eosinophils/high-power field (x 400)). Treatment by bouginage resulted in mucosal lacerations and transitory clinical improvement. Local steroid therapy for four weeks eliminated the symptoms.
Høyerup
Peter
P
H:S Rigshospitalet, Medicinsk Gastroenterologisk Klinik, Abdominalcentret, og Patologiafdelingen, Diagnostisk Center. peppep@sol.dk
Svendsen
Lars Bo
LB
Mogensen
Anne Mellon
AM
Staun
Michael
M
D000328:Adult; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000188:drug therapy / Q000473:pathology*; D004941:Esophagitis / Q000188:drug therapy / Q000473:pathology*; D005764:Gastroesophageal Reflux / Q000175:diagnosis; D006801:Humans; D008297:Male