title: Does aprotinin reduce blood loss in total hip arthroplasty?
abstract: This prospective randomized study examined the effects of aprotinin during total hip arthroplasty (THA). Fifty patients who were enrolled in the study received aprotinin or normal saline. Mean intraoperative blood loss was reduced from 1496 mL in the control group to 1073 mL in the aprotinin group. The mean transfusion unit was 1.56 in the aprotinin group and 3.8 in the control group.
authors.affiliation: 1st Orthopaedic Department, G. Papanikolaou Hospital, Aristotle University, Thessaloniki, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Petsatodis
authors.forename: E
authors.initials: E
authors.lastname: Samoladas
authors.forename: A
authors.initials: A
authors.lastname: Christodoulou
authors.forename: I
authors.initials: I
authors.lastname: Hatzokos
authors.forename: I
authors.initials: I
authors.lastname: Pournaras
mesh_terms: D000328:Adult; D000368:Aged; D007611:Aprotinin / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D006490:Hemostatics; D007611:Aprotinin