title: Telemonitoring of medication adherence in patients with schizophrenia.
abstract: Nonadherence to medication is a widespread problem in schizophrenia and is associated with poor clinical outcomes and inappropriate management and utilization of resources. The aim of the current investigation was to assess the impact of telemonitoring of medication adherence on symptomatology and service use in patients with schizophrenia. A total of 108 schizophrenia patients were randomized into three equal groups according to the approaches used to assess medication adherence; self-report, pill counting, and telemonitoring. Telementoring was achieved through an innovative new platform called @HOME. This platform offers clinicians early warnings about impeding nonadherence as well as information about the pattern of medication taking. Patient's adherence was observed over an 8-week period, during which patient's clinical status and service use were recorded. In comparison to the other two groups, patients using @HOME showed improvement in the Global Clinical Impression Scale and a significant reduction in emergency visits and medical appointments. The @HOME platform was highly acceptable by patients, caregivers, and professionals, and required minimal training for implementation. The results of the study suggest that the use of telemonitoring in psychiatric settings was both feasible and acceptable and may be associated with significant clinical and service related benefits.
authors.affiliation: Section of Neurobiology of Psychosis, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK. S.Frangou@iop.kcl.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Frangou
authors.forename: I
authors.initials: I
authors.lastname: Sachpazidis
authors.forename: A
authors.initials: A
authors.lastname: Stassinakis
authors.forename: G
authors.initials: G
authors.lastname: Sakas
mesh_terms: D000328:Adult; D003625:Data Collection; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012559:Schizophrenia / Q000188:drug therapy*; D012984:Software; D017216:Telemedicine