Tissue engineering templates using minimal surfaces.
The status quo of tissue engineering can be summarized as "a random walk through the design space". The existing scaffold designs based on computeraided design (CAD) and solid freeform fabrication (SFF) are anti-biomorphic and mechanically weak cubic partitions with sharp edges. We introduce minimal surface based unit cells to create biomorphic scaffolds with optimal stress/strain distribution and superior mechanical strength.
Rajagopalan
Srinivasan
S
Biomedical Imaging Resource, Mayo Clinic College of Medicine, Rochester, MN, USA.
Cameron
Bruce M
BM
Robb
Richard A
RA
D003198:Computer Simulation; D017076:Computer-Aided Design; D003238:Connective Tissue; D006801:Humans; D014481:United States