Multiplicity-edited broadband HMBC NMR spectra.
A new, edited HMBC experiment is introduced that leads to two subspectra according to the number of protons attached to 13C nuclei being even or odd, i.e. one subspectrum with C + CH2 and another with CH + CH3. This experiment can be useful for resolving spectral overlap among the typically large number of peaks in HMBC spectra. It is implemented in a broadband version similar to broadband HMBC and demonstrated on prednisolone [(11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione].
Nyberg
Nils T
NT
Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.
Sørensen
Ole W
OW
D002247:Carbon Isotopes / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008697:Methane / Q000737:chemistry; D015394:Molecular Structure; D011239:Prednisolone / Q000737:chemistry*; D011522:Protons
D002247:Carbon Isotopes; D011522:Protons; D006859:Hydrogen; D011239:Prednisolone; D008697:Methane