Warfarin use and the risk of motor vehicle crash in older drivers.
OBJECTIVE
On the basis of a recent report, we assessed whether the use of warfarin by elderly drivers results in an increased risk of motor vehicle crash.


METHODS
We used computerized records of Quebec insurance programmes, covering a population of 7 million people, to conduct a case-control study based on 5,579 cases and 12,911 controls.


RESULTS
The rate of injurious motor vehicle crash associated with the use of warfarin in the past year was not elevated (rate ratio 0.74; 95% confidence interval 0.55, 1.05).


CONCLUSIONS
Warfarin therapy does not appear to increase the risk of motor vehicle accidents in elderly drivers.
Delaney
J A 'Chris'
JA
Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Center, McGill University, Montreal, Canada.
Opatrny
Lucie
L
Suissa
Samy
S
D000063:Accidents, Traffic / Q000706:statistics & numerical data*; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects*; D001334:Automobile Driving; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D011792:Quebec; D018570:Risk Assessment; D014859:Warfarin / Q000009:adverse effects*
D000925:Anticoagulants; D014859:Warfarin