[New epidemiology of acute gastrointestinal hemorrhage].
Due to progress in general medicine and especially in gastroenterology, the incidence of acute gastrointestinal hemorrhage could be expected to have decreased during the last 25 years. However, published epidemiological data cannot, in general, fulfill this hope. The interpretation of potential trends is, however, often limited by low study quality. For example, questionable bleeding sources such as erosions in the upper gastrointestinal tract or colon diverticula are often rather uncritically named the definitive causes of bleeding. However, there is clear evidence of changes in grouping of patients. After the almost complete disappearance of Helicobacter pylori in younger indigenous populations of most industrialized countries, it is mostly elderly comorbid people with additional risk factors (NSAID use, low-dose aspirin, anticoagulation) who are affected. Not unexpectedly, this group has generally experienced no change in incidence and in fact shows a deterioration of prognosis in case of acute bleeding.
Koelz
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HR
Abteilung für Gastroenterologie, Medizinische Klinik, Stadtspital Triemli Zürich. hansrudolf.koelz@triemli.stzh.ch
Arn
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D000208:Acute Disease; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D015984:Causality; D003430:Cross-Sectional Studies; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology* / Q000209:etiology; D006306:Health Surveys; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology; D006489:Hemostatic Techniques / Q000639:trends; D006801:Humans; D010438:Peptic Ulcer Hemorrhage / Q000453:epidemiology / Q000209:etiology
D000894:Anti-Inflammatory Agents, Non-Steroidal