title: Natural insights for chemical biologists.
abstract: Chemical biologists studying natural-product pathways encoded in genomes have unearthed new chemistry and insights into the evolution of biologically active metabolites.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. christopher_walsh@hms.harvard.edu
authors.forename: Christopher T
authors.initials: CT
authors.lastname: Walsh
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D001671:Biochemistry / Q000639:trends*; D001761:Bleomycin / Q000096:biosynthesis / Q000138:chemical synthesis; D019295:Computational Biology / Q000639:trends; D015195:Drug Design; D007559:Ivermectin / Q000031:analogs & derivatives / Q000138:chemical synthesis; D008148:Lovastatin / Q000096:biosynthesis / Q000138:chemical synthesis; D013058:Mass Spectrometry / Q000639:trends; D015394:Molecular Structure; D040901:Proteomics / Q000639:trends
chemical_list: D001426:Bacterial Proteins; D001761:Bleomycin; D007559:Ivermectin; C019264:avermectin; D008148:Lovastatin