Nocardiosis in a patient with primary anti-phospholipid syndrome.
Antiphospholipid syndrome is an autoimmune disease that is characterised by tendency to thrombosis, obstetrical and hematological complications. Corticosteroids may be useful for therapy of some features of this syndrome, such as thrombocytopenia. Nocardia is an important opportunistic infectious agent in immunocompromised hosts, i.e. in patients taking corticosteroids. It is important to be aware of these rare complications, which are correlated with the prognosis. In this paper, we report a patient with primary anti-phospholipid syndrome treated by corticosteroid, who developed disseminated nocardiosis.
Soy
Mehmet
M
Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, 22100 Turkey. msoy_2000@yahoo.com
Oktun
Müşerref Tatman
MT
Tunçbilek
Nermin
N
Ermantaş
Nilay
N
Okten
Omür
O
Altinay
Gündeniz
G
Turgut
Burhan
B
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000188:drug therapy*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002738:Chloroquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008775:Methylprednisolone / Q000009:adverse effects*; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D013921:Thrombocytopenia / Q000188:drug therapy* / Q000209:etiology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; C023676:chloroquine diphosphate; D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002738:Chloroquine; D008775:Methylprednisolone