title: Assessment of acute spontaneous intracerebral hematoma by CT perfusion imaging.
abstract: A single-section deconvolution-derived computerized tomographic perfusion imaging was performed in 45 patients (22 male and 23 female; mean age=69.89+/-10.07 years) with acute supratentorial spontaneous intracerebral hemorrhage. Mean rCBF and rCBV were lower in the hemorrhagic core than in the perihematomal low density area (p<0.001), and in the perihematomal low density area than in normal appearing brain parenchyma (p<0.001). Mean rMTT values were higher in perihematomal low density area than in normal appearing area (p<0.01) and in both hemorrhagic and perihematomal area than in controlateral ROI (p<0.001). There were no differences in rMTT mean values between hemorrhagic core and perihematomal area, as well as between normal appearing and controlateral areas. We found a concentric distribution of all CT perfusion parameters characterized by an improvement from the core to the periphery, with low perihematomal rCBF and rCBV values suggesting edema formation.
authors.affiliation: Neuroradiology Unit, Department of Neuroscience, Arcispedale S. Anna, Corso della Giovecca 203, 44100 Ferrara, Italy. henryfai@tin.it
authors.forename: E
authors.initials: E
authors.lastname: Fainardi
authors.forename: M
authors.initials: M
authors.lastname: Borrelli
authors.forename: A
authors.initials: A
authors.lastname: Saletti
authors.forename: R
authors.initials: R
authors.lastname: Schivalocchi
authors.forename: M
authors.initials: M
authors.lastname: Russo
authors.forename: C
authors.initials: C
authors.lastname: Azzini
authors.forename: C
authors.initials: C
authors.lastname: Cavallo
authors.forename: S
authors.initials: S
authors.lastname: Ceruti
authors.forename: A
authors.initials: A
authors.lastname: Chieregato
authors.forename: R
authors.initials: R
authors.lastname: Tamarozzi
mesh_terms: D000208:Acute Disease; D000368:Aged; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006406:Hematoma / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed