title: Risk factors for groin wound infection after femoral artery catheterization: a case-control study.
abstract: OBJECTIVE
  Groin wound infection (GWI) after femoral artery catheterization is unusual. However, several reports of GWI associated with the use of a Perclose device appear in the surgical literature.
  
  
  METHODS
  A case-control study.
  
  
  METHODS
  We pooled 23 cases and 83 controls from a university hospital and a community medical center.
  
  
  METHODS
  A case was defined as a patient who developed a GWI after a femoral artery catheterization. At the university hospital, 3 controls were randomly selected from the at-risk population and matched to each case by time of procedure only (within 2 weeks). At the community medical center, 4 controls were selected and matched to each case by time of procedure (within 2 weeks), sex, and age (within 5 years).
  
  
  RESULTS
  We considered several covariates, including age, sex, body mass index, medical conditions, Perclose use, hematoma formation, and antithrombotic therapy. In a multivariate model, only hematoma formation (odds ratio, 68.8; 95% confidence interval, 12.1-391.4) and glycoprotein IIb/IIIa platelet inhibitor therapy (odds ratio, 6.1; 95% confidence interval, 1.1-33.6) were statistically significant predictors of GWI; Perclose use (odds ratio, 0.9; 95% confidence interval, 0.2-3.7) was not a statistically significant predictor of GWI. However, most of the hematomas (15/17) formed after procedures during which a Perclose device was used.
  
  
  CONCLUSIONS
  Perclose use did not have any additional effect on GWI risk beyond the effect that hematoma formation had.
authors.affiliation: Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA. philip-polgreen@uiowa.edu
authors.forename: Philip M
authors.initials: PM
authors.lastname: Polgreen
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Diekema
authors.forename: Jeff
authors.initials: J
authors.lastname: Vandeberg
authors.forename: R Todd
authors.initials: RT
authors.lastname: Wiblin
authors.forename: Yi Yi
authors.initials: YY
authors.lastname: Chen
authors.forename: Sherry
authors.initials: S
authors.lastname: David
authors.forename: Dianne
authors.initials: D
authors.lastname: Rasmus
authors.forename: Nicole
authors.initials: N
authors.lastname: Gerdts
authors.forename: Angelena
authors.initials: A
authors.lastname: Ross
authors.forename: Louis
authors.initials: L
authors.lastname: Katz
authors.forename: Loreen A
authors.initials: LA
authors.lastname: Herwaldt
mesh_terms: D016022:Case-Control Studies; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000295:instrumentation; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005263:Femoral Artery; D006119:Groin; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology