title: The role of the Rcs phosphorelay in Enterobacteriaceae.
abstract: The Rcs phosphorelay is composed of the sensor kinase, RcsC, the HPt-domain protein RcsD and the response regulator, RcsB. In this review we discuss the role of the Rcs phosphorelay in the Enterobacteriaceae, highlighting the observation that the Rcs phosphorelay appears to play a key role in the temporal regulation of biofilm formation and pathogenicity.
authors.affiliation: Molecular Microbiology Laboratory, Department of Biology and Biochemistry, University of Bath, UK.
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Huang
authors.forename: Lionel
authors.initials: L
authors.lastname: Ferrières
authors.forename: David J
authors.initials: DJ
authors.lastname: Clarke
mesh_terms: D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism*; D018441:Biofilms; D004755:Enterobacteriaceae / Q000378:metabolism* / Q000472:pathogenicity; D004926:Escherichia coli / Q000502:physiology; D029968:Escherichia coli Proteins / Q000378:metabolism*; D009097:Multienzyme Complexes / Q000378:metabolism*; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D012475:Salmonella / Q000472:pathogenicity / Q000502:physiology; D015398:Signal Transduction; D037521:Virulence Factors / Q000235:genetics / Q000502:physiology; D015007:Yersinia / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D009097:Multienzyme Complexes; D037521:Virulence Factors; C074889:RcsB protein, Bacteria; D010770:Phosphotransferases; D011494:Protein Kinases; C434271:rcsD protein, E coli; D010749:Phosphoprotein Phosphatases