title: Ex vivo anticholinesterase activity of benzoic acid derivatives.
abstract: p-Aminobenzoic acid (p-ABA) derivatives were evaluated as acetylcholinesterase inhibitors (AChEIs). Finding a correlation between AChE activity with the partition coefficient (log P) and the highest occupied molecular orbital (HOMO) energy of the compounds.
authors.affiliation: Sección de Estudios de Posgrado e Investigación y Departamento de Bioquímica, Escuela Superior de Medicina, IPN, Plan de San Luis y Díaz Mirón, DF, 11340 México, Mexico.
authors.forename: José
authors.initials: J
authors.lastname: Correa-Basurto
authors.forename: Judith
authors.initials: J
authors.lastname: Espinosa-Raya
authors.forename: Iván
authors.initials: I
authors.lastname: Vázquez-Alcántara
authors.forename: Cesar A
authors.initials: CA
authors.lastname: Flores-Sandoval
authors.forename: José
authors.initials: J
authors.lastname: Trujillo-Ferrara
mesh_terms: D000818:Animals; D019817:Benzoic Acid / Q000737:chemistry* / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D002802:Cholinesterases / Q000378:metabolism*; D008297:Male; D051379:Mice; D015394:Molecular Structure
chemical_list: D002800:Cholinesterase Inhibitors; D019817:Benzoic Acid; D002802:Cholinesterases