title: Neurodevelopmental delays in children with deformational plagiocephaly.
abstract: BACKGROUND
  The purpose of this study was to determine whether, in fact, infants with deformational plagiocephaly, or plagiocephaly without synostosis, demonstrated cognitive and psychomotor developmental delays when compared with a standardized population. Through this study, we chose to expand upon our earlier findings from 2001 on patients with deformational plagiocephaly.
  
  
  METHODS
  The study population includes a total of 110 consecutive patients, prospectively followed then retrospectively reviewed. Each infant was assessed using the Bayley Scales of Infant Development-II scoring system. The developmental analysis was categorized as either mental or psychomotor using the mental developmental index or the psychomotor developmental index, respectively. These infants were subcategorized into four groups: accelerated, normal, mild, or severely delayed. The groups were then compared with a standardized Bayley's age-matched population, using chi-square test goodness-of-fit tests.
  
  
  RESULTS
  Infants with deformational plagiocephaly were found to have significantly different psychomotor development indexes and mental developmental indexes when compared with the standardized population (p < 0.0001; p < 0.0001). With regards to the mental developmental index scores, none of the infants with deformational plagiocephaly were accelerated, 90 percent were normal, 7 percent were mildly delayed, and 3 percent were severely delayed. With regards to the psychomotor development index scores, none of infants were accelerated, 74 percent were normal, 19 percent were mildly delayed, and 7 percent were severely delayed.
  
  
  CONCLUSIONS
  This study indicates that before any intervention, infants with deformational plagiocephaly show significant delays in both mental and psychomotor development. Also of particular note is that no child with deformational plagiocephaly showed accelerated development.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Oklahoma School of Medicine, Health Science Center, Oklahoma City, Oklahoma, USA. shark4rk@aol.com
authors.forename: Rouzbeh K
authors.initials: RK
authors.lastname: Kordestani
authors.forename: Shaurin
authors.initials: S
authors.lastname: Patel
authors.forename: David E
authors.initials: DE
authors.lastname: Bard
authors.forename: Robin
authors.initials: R
authors.lastname: Gurwitch
authors.forename: Jayesh
authors.initials: J
authors.lastname: Panchal
mesh_terms: D000428:Alcohol Drinking; D003072:Cognition Disorders / Q000209:etiology*; D015986:Confounding Factors, Epidemiologic; D002658:Developmental Disabilities / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D049068:Plagiocephaly, Nonsynostotic / Q000150:complications*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011446:Prospective Studies; D011596:Psychomotor Disorders / Q000209:etiology*; D019966:Substance-Related Disorders