title: The tongue as an alternative donor site for graft urethroplasty: a pilot study.
abstract: OBJECTIVE
  Urethroplasty with a buccal mucosal graft provides excellent clinical results but it may also cause oral complications in some cases. The mucosa covering the lateral and under surface of the tongue is identical in structure with that lining the rest of the oral cavity. We evaluated LMGs for urethroplasty.
  
  
  METHODS
  From January 2001 to September 2004, 8 men 34 to 65 years old (mean age 46.1) with urethral strictures 1.5 to 4.5 cm long were selected for 1-stage dorsal onlay urethroplasty. The site of the harvest graft was the lateral mucosal lining of the tongue. Postoperatively all patients were followed with urethrography, uroflowmetry, cystourethrography and flexible urethroscopy after 3 and 12 months. Successful reconstruction criteria were peak flow rate greater than 15 ml per second and no need for postoperative urethral dilation.
  
  
  RESULTS
  Median followup was 18 months (mean 22.1, range 3 to 47). Seven cases were successful. One patient had a partial urethral stricture. In successful cases cystourethrography revealed no significant graft contractures or sacculations and at flexible urethroscopy LMG was almost indistinguishable from native urethra. There were no pain, esthetic or functional complications at the donor site.
  
  
  CONCLUSIONS
  Harvesting the LMG is feasible and easy to perform. Compared with the buccal mucosal graft the LMG seems to be associated with less postoperative pain and a minor risk of donor site complications. These preliminary functional and esthetic data are satisfactory.
authors.affiliation: Department of Urology Luciano Giuliani, University of Genoa, Genoa, Milan, Italy. alchiedesimonato@libero.it
authors.forename: Alchiede
authors.initials: A
authors.lastname: Simonato
authors.forename: Andrea
authors.initials: A
authors.lastname: Gregori
authors.forename: Andrea
authors.initials: A
authors.lastname: Lissiani
authors.forename: Stefano
authors.initials: S
authors.lastname: Galli
authors.forename: Francesco
authors.initials: F
authors.lastname: Ottaviani
authors.forename: Roberta
authors.initials: R
authors.lastname: Rossi
authors.forename: Anna
authors.initials: A
authors.lastname: Zappone
authors.forename: Giorgio
authors.initials: G
authors.lastname: Carmignani
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation*; D010865:Pilot Projects; D014059:Tongue / Q000637:transplantation*; D014521:Urethra / Q000601:surgery*; D014525:Urethral Stricture / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods