A resin-modified glass ionomer cement barrier for treating degree II furcation defects: a pilot study in dogs.
OBJECTIVE
The aim of this study was to evaluate in an animal model the healing of degree II furcation defects treated with: an experimental barrier of resin-modified glass-ionomer cement (GIC), a polylactic acid barrier (GUI), and flap surgery (CTR).


METHODS
In 3 beagles, 18 class II furcation defects were surgically produced in mandibular and maxillary premolars and exposed to plaque accumulation for 21 days. Following a full flap, notches were made at the base to the bone defect. GIC barriers were prepared immediately before use from a commercial product and fit to place with the same product. The GIC barriers were removed after 30 days and the dogs euthanized after 120 days. Histologic sections were analyzed in a computer-assisted microscope. Epithelium, new cementum with inserting fibers, and connective tissue lining the root surface in-between notches were measured and medians of percentage values calculated.


RESULTS
In the GIC, epithelium constituted 3.5% (median values) of the notch-to-notch root area; new cementum was 83.6% and connective tissue 12.9%. These values were 0%, 73.6%, and 26.4% for the GUI group and 35.6%, 43.2%, and 0% for the CTR group. Bone fill median values were 54.3% for GIC, 20.6% for GUI, and 24.6% for CTR.


CONCLUSIONS
GIC and GUI prevented epithelial migration and promoted the formation of new periodontal tissues in experimentally induced class II furcation defects in dogs.
Miranda
Letícia Algarves
LA
Graduate Programme in Periodontology, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. Leticia.Miranda@ofa.ki.se
Gomes
Sabrina Carvalho
SC
Soares
Ilson José
IJ
Oppermann
Rui Vicente
RV
D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D002951:Citrates; D003238:Connective Tissue / Q000502:physiology; D003739:Dental Cementum / Q000502:physiology; D004285:Dogs; D004848:Epithelium / Q000502:physiology; D005260:Female; D017823:Furcation Defects / Q000601:surgery*; D005899:Glass Ionomer Cements; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation*; D008567:Membranes, Artificial; D010865:Pilot Projects; D011091:Polyesters
D001672:Biocompatible Materials; D002951:Citrates; D005899:Glass Ionomer Cements; C105021:Guidor; D008567:Membranes, Artificial; D011091:Polyesters