title: Improved isotopic deuterium labeling at the diastereotopic methyl group of leucine: a synthetic route to (4S)- and (4R)-[5-2H1]leucine.
abstract: Two isotopomers of deuterium-labeled leucine in the diastereotopic methyl group were synthesized from inexpensively available (R)- and (S)-citronellol in a more convenient way than by previous methods.
authors.affiliation: Department of Earth and Planetary Sciences, Graduate School of Sciences, Kyushu University, Fukuoka, Japan. nyama@geo.kyushu-u.ac.jp
authors.forename: Noriaki
authors.initials: N
authors.lastname: Yamauchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Endoh
mesh_terms: D003903:Deuterium / Q000737:chemistry*; D007553:Isotope Labeling / Q000379:methods*; D007930:Leucine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003903:Deuterium; D007930:Leucine