Sensitive chiral analysis by capillary electrophoresis.
In this review, an updated view of the different strategies used up to now to enhance the sensitivity of detection in chiral analysis by CE will be provided to the readers. With this aim, it will include a brief description of the fundamentals and most of the recent applications performed in sensitive chiral analysis by CE using offline and online sample treatment techniques (SPE, liquid-liquid extraction, microdialysis, etc.), on-column preconcentration techniques based on electrophoretic principles (ITP, stacking, and sweeping), and alternative detection systems (spectroscopic, spectrometric, and electrochemical) to the widely used UV-Vis absorption detection.
García-Ruiz
Carmen
C
Departamento de Química Analítica, Facultad de Química, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain.
Marina
María Luisa
ML
D019075:Electrophoresis, Capillary / Q000379:methods*; D008968:Molecular Conformation; D004364:Pharmaceutical Preparations / Q000302:isolation & purification; D011506:Proteins / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
D004364:Pharmaceutical Preparations; D011506:Proteins