Dissociable modulating effect of repetitive transcranial magnetic stimulation on sensory and pain perception.
The effects of high frequency repetitive transcranial magnetic stimulation on sensory perception and the pain tolerance thresholds were investigated applying both motor cortex stimulation and medial frontal cortex stimulation in normal study participants. Both the sensory perception and pain tolerance thresholds were significantly increased in the motor cortex stimulation, whereas the pain tolerance thresholds, but not the sensory perception was significantly decreased in the medial frontal cortex stimulation. These results suggest the dissociable modulating effects of sensory and pain perception by the high frequency repetitive transcranial magnetic stimulation on the medial pain regulating system, but not the lateral pain regulating system.
Yoo
Woo-Kyoung
WK
Department of Physical Medicine and Rehabilitation Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
Kim
Yun-Hee
YH
Doh
Won-Su
WS
Lee
Ji-Hun
JH
Jung
Kwang-Ik
KI
Park
Dong-Sik
DS
Park
Eun-Sook
ES
D000328:Adult; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000502:physiology / Q000528:radiation effects*; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement / Q000379:methods; D010465:Perception / Q000528:radiation effects*; D012684:Sensory Thresholds / Q000528:radiation effects*; D013997:Time Factors; D050781:Transcranial Magnetic Stimulation