Fermentative production of L-lysine: fungal fermentation and mutagenesis-II: a review.
Lysine has been recognized as one of the most deficient essential amino acids. It is an economically important food and feed supplement. It has also got various pharmaceutical applications in the formulation of diets with balanced amino acid concentration and in amino acid infusions. Chemical, enzymatic and fermentation processes have been used to synthesize lysine. The objective of this review is to outline the research work of various scientists which provide important and beneficial information regarding the production of lysine through fungal fermentation and mutagenesis. Moreover, methods to improve the total yield and quality of lysine are also presented.
Shah
Abdul Haleem
AH
Department of Chemistry, Gomal University, Dera Ismail Khan, NWFP, Pakistan.
Hameed
Abdul
A
Khan
Gul Majid
GM