title: Risk factors for falls in older disabled women with diabetes: the women's health and aging study.
abstract: BACKGROUND
  The aim of this study was to determine whether older disabled women with diabetes have an increased risk of falls compared to women without diabetes and to identify fall risk factors among this high-risk subgroup of patients.
  
  
  METHODS
  Data are from the Women's Health and Aging Study I (n = 1002, age > or = 65 years), a prospective, population-based cohort study of the one third most disabled women in the Baltimore (MD) urban community-dwelling population. Participants were followed semiannually for 3 years. Falls were ascertained at each interview. Diabetes was ascertained by means of a standardized algorithm using multiple sources of information.
  
  
  RESULTS
  Baseline prevalence of diabetes was 15.5%. Of the 878 women who participated in at least one follow-up visit and were able to walk at baseline, 64.9% fell at least once during the study and 29.6% experienced two or more falls during a follow-up interval. After adjustment for traditional risk factors, women with diabetes had a higher probability of any fall (odds ratio [OR] 1.38; 95% confidence interval [CI], 1.04-1.81) and of falling two or more times during a follow-up interval (OR 1.69; CI, 1.18-2.43), compared with women without diabetes. Among diabetic women, presence of widespread musculoskeletal pain (OR 5.58; CI, 1.89-16.5), insulin therapy (OR 2.02; CI, 1.10-3.71), overweight (OR 3.50; CI, 1.21-10.1), and poor lower-extremity performance (OR 7.76; CI, 1.03-58.8) were independently associated with increased likelihood of recurrent falls, after adjusting for major risk factors. There were synergistic effects of diabetes and lower-extremity pain and also diabetes and body mass index levels on the risk of falling (p for interactions <.05).
  
  
  CONCLUSIONS
  Even among disabled older women diabetes is associated with an increased risk of falling, independent of established fall risk factors. In this specific group of older women, pain, high body mass index, and poor lower-extremity performance are powerful predictors of falling.
authors.affiliation: Department of Clinical and Experimental Medicine, University of Ferrara, Via Savonarola, 9, 44100 Ferrara, Italy. vlt@unife.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Volpato
authors.forename: Suzanne G
authors.initials: SG
authors.lastname: Leveille
authors.forename: Caroline
authors.initials: C
authors.lastname: Blaum
authors.forename: Linda P
authors.initials: LP
authors.lastname: Fried
authors.forename: Jack M
authors.initials: JM
authors.lastname: Guralnik
mesh_terms: D000058:Accidental Falls / Q000706:statistics & numerical data*; D000368:Aged; D000369:Aged, 80 and over; D003920:Diabetes Mellitus; D006233:Persons with Disabilities; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D012307:Risk Factors