Acetylation percentage method for determination of acetylator status in human volunteers and tuberculous patients.
Acetylation percentage method described here is rapid and economical. A comparison has been made between plasma half life (t (1/2)), acetylation ratio and acetylation percentage methods for the determination of phenotyping. Isoniazid (INH) was selected as a test drug. In 120 healthy volunteers and 60 tuberculosis patients, acetylation percentage method has been found simple and reliable as compared to the other methods.
Sohrani
A S
AS
Department of Pharmacy, Bahauddin Zakariya University, Multan-60800, Pakistan.
Ahmad
B
B
Janbaz
K H
KH