[Epidemiological, clinical and parasitological data about canine leishmaniasis in Tunisia].
Epidemiological, clinical and parasitological data concerning canine leishmaniasis were collected in two Tunisian populations of dogs, different in breed and life style: 23 rural dogs and 26 dogs of European breeds. All were symptomatic and lived in the north of Tunisia where human visceral and cutaneous leishmaniasis caused by Leishmania infantum are endemic. Leishmaniasis has been confirmed in all dogs by serology or/and by parasitic identification. Significant differences concerning age and symptoms suggest a higher susceptibility to infection in European imported breeds. In fact individuals of this population were significantly younger; 81% were less than 5 years old whereas 57% of the autochthonous rural dogs were more than 5 years old with 31% of them being older than 9 (p = 0.014). In spite of their young age, 75% of imported breeds presented an affection of their general state with more frequent cutaneous symptoms than the rural dogs (96% versus 69%, p = 0.02). Isoenzyme typing of 31 strains, obtained from the two populations, from different sites (blood, lymph nodes, spleen) has only identified the zymodeme Leishmania infantum MON-1. This stresses the need of more investigations to determine reservoirs of the other enzymatic variants identified in humans in Tunisia and Mediterranean basin.
Bouratbine
A
A
Laboratoire de parasitologie clinique, Institut Pasteur de Tunis, 13 Place Pasteur. B.P. 74. 1002, Tunis Belvedère, Tunisie. aida.bouratbine@pasteur.rns.tn
Aoun
K
K
Gharbi
M
M
Haouas
N
N
Zaroui
J
J
Harrat
Z
Z
Baba
H
H
Darghouth
M A
MA
D000367:Age Factors; D000818:Animals; D004197:Disease Reservoirs; D004198:Disease Susceptibility; D004283:Dog Diseases / Q000453:epidemiology / Q000469:parasitology*; D004285:Dogs / Q000145:classification; D019353:Endemic Diseases; D006801:Humans; D018314:Leishmania infantum / Q000145:classification / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology / Q000662:veterinary; D007898:Leishmaniasis, Visceral / Q000453:epidemiology / Q000662:veterinary*; D012424:Rural Population; D014416:Tunisia / Q000453:epidemiology; D015047:Zoonoses / Q000453:epidemiology