[The effect of betulonic acid and its alanine amide derivatives on rat liver parenchyma repair during postcytostatic period].
The effects of betulonic acid, its p-alanine amide derivative, and p-alanine amide derivative of betulonic acid methyl ether on the histologic structure of rat liver have been studied on the model of experimental polychemotherapy in rats. These agents significantly decrease the dystrophic and cytolytic damage of hepatocytes and increase the repair processes in liver parenchyma.
Grek
O R
OR
Pozdniakova
S V
SV
Nadeev
A P
AP
Pronin
V S
VS
Zhukova
N A
NA
Sorokina
I V
IV
Volkova
E B
EB
Tolstikova
T G
TG
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D022781:Hepatocytes / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000293:injuries* / Q000473:pathology; D008115:Liver Regeneration / Q000187:drug effects*; D009828:Oleanolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D051381:Rats; D000094062:Betulinic Acid
D000970:Antineoplastic Agents; D009828:Oleanolic Acid; C118308:betulonic acid; D000094062:Betulinic Acid