title: An efficient synthesis of new C-2 aryl substituted quinolines based on three component imino Diels-Alder reaction.
abstract: New effective approach to the synthesis of a wide variety of C-2 nitro or aminophenyl substituted quinolines was reported using diverse intermediate 4-(2-oxopyrrolinidyl-1)-tetrahydroquinolines that were prepared by a three component imino Diels-Alder reaction was reported. The key aromatisation process occurs cleanly with the loss of the 2-oxopyrrolinidyl-1 fragment.
authors.affiliation: Laboratorio de Química Orgánica y Biomolecular, Escuela de Química, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia. kouznet@uis.edu.co
authors.forename: Vladimir V
authors.initials: VV
authors.lastname: Kouznetsov
authors.forename: Arnold R Romero
authors.initials: AR
authors.lastname: Bohórquez
authors.forename: Luis Astudillo
authors.initials: LA
authors.lastname: Saavedra
authors.forename: Ricardo Fierro
authors.initials: RF
authors.lastname: Medina
mesh_terms: D003500:Cyclization; D007097:Imines / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007097:Imines; D011804:Quinolines