Thermodynamic dissociation constant studies of caffeine at different temperatures and in organic water solvent mixture.
Thermodynamic dissociation studies have been carried out potentiometrically at various temperatures from 25 to 50 degrees C and in 10, 20, 30 and 40% v/v dioxane-water solvent mixture at 25 degrees C. The influence of temperature and nature of solvent on dissociation equilibria of caffeine is being investigated. A computer program in GW-BASIC has been used to calculate the pK values.
Saeeduddin
Shah Abdul Latif College Mirpurkhas (Sindh), Pakistan.
Khanzada
A W K
AW