Molecular diagnostics of non-small cell lung cancer using mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration.
Non-small cell lung cancer is a common cancer with significant mortality. Accurate and early staging of this cancer has a significant impact on outcome. Endoscopic ultrasound-guided fine needle aspiration of involved mediastinal lymph nodes is critical for staging. Several molecular markers have been identified recently in association with non-small cell carcinoma of the lung that are promising to make early detection of metastatic disease more reliable.
Al-Haddad
M
M
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Wallace
M B
MB
D014408:Biomarkers, Tumor / Q000032:analysis; D044963:Biopsy, Fine-Needle; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D019160:Endosonography; D018773:Genes, erbB-1; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D008198:Lymph Nodes / Q000378:metabolism*; D008207:Lymphatic Metastasis; D008482:Mediastinum; D025202:Molecular Diagnostic Techniques; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019098:Telomerase / Q000032:analysis
D014408:Biomarkers, Tumor; D019098:Telomerase