title: Early pre-eclampsia: what proportion of women qualify for expectant management and if not, why not?
abstract: OBJECTIVE
  To determine what proportion of women with early pre-eclampsia qualify for expectant management and the magnitude of factors excluding this approach.
  
  
  METHODS
  A prospective case series with continuous data capture over one year at a tertiary referral centre. All women (n=169) with singleton pregnancies, presenting with early (> or =20 and <34 weeks' gestation) pre-eclampsia, were admitted, stabilised and evaluated. Major maternal or fetal complications at this stage were indications for delivery. However, when the pregnancy was otherwise stable, expectant management was commenced if the gestation was >or =24 weeks. Termination was offered from 20 to 23 weeks' gestation.
  
  
  RESULTS
  Of the 169 women admitted, 82 (48.5%) were managed expectantly and 87 (51.5%) delivered after stabilisation and evaluation. Early fetal distress (32%) and major maternal complications (28%) were the most frequent reasons preventing expectant management. Ascites (18%) and HELLP syndrome (13%) ranked highest amongst the maternal complications.
  
  
  CONCLUSIONS
  In this study, almost half of the women presenting with early onset pre-eclampsia qualified for expectant management. Early fetal distress was the most frequent reason preventing expectant management.
authors.affiliation: Department of Obstetrics and Gynaecology, Tygerberg Hospital and Stellenbosch University, P.O. Box 19063, Tygerberg 7505, South Africa.
authors.forename: David R
authors.initials: DR
authors.lastname: Hall
authors.forename: Debbie
authors.initials: D
authors.lastname: Grové
authors.forename: Erna
authors.initials: E
authors.lastname: Carstens
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005316:Fetal Distress; D006801:Humans; D010346:Patient Care Management / Q000706:statistics & numerical data*; D011225:Pre-Eclampsia / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods / Q000706:statistics & numerical data*; D011446:Prospective Studies; D013019:South Africa