Parvovirus b19 infection in HIV patient with pure red cell aplasia.
Anemia in HIV-infected patients is a common clinical manifestation. We report on a 31-year-old Thai male, who had been HIV positive for 6 years, did not harbor any opportunistic infection, and had been receiving Highly Active Anti Retroviral Therapy (HAART) for one month, and who developed severe anemia. Investigation revealed pure red cell aplasia, suspected secondary to parvovirus B19 infection. This diagnosis was confirmed by the detection of parvovirus B19 DNA in his serum. He received blood transfusions for supportive treatment and continued on HAART to improve his immune status and to resolve the anemia. This case suggests that parvovirus B19 infection should be considered as a possible cause of anemia in HIV-infected individuals.
Sanphasitvong
Wanviput
W
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Poovorawan
Kittiyod
K
Boonsuk
Pitirat
P
Assanasen
Thamathorn
T
Na Nakorn
Thanyaphong
T
Poovorawan
Yong
Y
D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001483:Base Sequence; D017931:DNA Primers; D004279:DNA, Viral / Q000097:blood; D006801:Humans; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications*; D016732:Parvovirus B19, Human / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012010:Red-Cell Aplasia, Pure / Q000209:etiology*; D013785:Thailand
D017931:DNA Primers; D004279:DNA, Viral