Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes.
The title compounds are enantioselectively synthesized in just two preparative steps, making use of the Ugi-four-component reaction with an amino acid as chiral component, followed by a gold-catalyzed hydroamination.
Kadzimirsz
Daniel
D
Fakultät für Chemie, Ruhr-Universität Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany.
Hildebrandt
Dirk
D
Merz
Klaus
K
Dyker
Gerald
G