[The main pharmacology study of ZhongSheng capsule dosage form changing].
OBJECTIVE
To study pharmacological action variety of ZhongSheng Pill dosage form changing from pill to capsule.


METHODS
Using anti-pathogenic microbe, antipyretic and antipyrotic effect as the pharmacological index,we compared the pharmacological action between Zhongsheng Pill formation and Capsule formation.


RESULTS
Zhongsheng Capsule had various degrees extraneous antagonistic actions against familiar and conditioned pathogenic bacteria and virus of respiratory tract. Furthermore it coud also reduce the death ratio of mouse infected by staphylococcus aureus and influenza virus, remove fever and diminish inflammation. All these effects had the dose-effect relationship. There were no difference between pill fromation and cpasule formation.


CONCLUSIONS
Zhongsheng Capsule retain the original pharmacological action of Zhongsheng Pill after dosage form changing.
Rong
Xianglu
X
Guangzhou University of TCM, Guangzhou 510405.
Xing
Yanhong
Y
Wu
Qinghe
Q
Huang
Ping
P
D000818:Animals; D002214:Capsules; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005334:Fever / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology*; D009982:Gammainfluenzavirus / Q000187:drug effects; D008297:Male; D051379:Mice; D009929:Organ Size / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D051381:Rats; D012229:Rhinovirus / Q000187:drug effects*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000473:pathology*; D013211:Staphylococcus aureus / Q000187:drug effects*
D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal