title: Central nervous system toxicity induced by irinotecan.
authors.forename: Paul
authors.initials: P
authors.lastname: Hamberg
authors.forename: Richard C J M
authors.initials: RC
authors.lastname: Donders
authors.forename: Daan
authors.initials: D
authors.lastname: ten Bokkel Huinink
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000009:adverse effects*; D002166:Camptothecin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D002490:Central Nervous System / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013618:Tachyphylaxis
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002166:Camptothecin