title: Low-field compact magnetic resonance imaging system for the hand and wrist in rheumatoid arthritis.
abstract: OBJECTIVE
  To investigate the feasibility of an originally developed compact MRI system for evaluating rheumatoid arthritis (RA), and determine its advantages and disadvantages as an imaging modality for evaluating RA.
  
  
  METHODS
  We prospectively studied 13 healthy controls with no clinical symptoms of arthritis, and 13 patients with hand and wrist pains (including pain from RA) with a 0.2 T permanent-magnet compact MR imager. All MR images were obtained while the subjects were in a sitting position. Coronal three-dimensional spin-echo T1-weighted images and coronal two-dimensional short tau inversion recovery (STIR) images were obtained with image matrix = 256 x 128 and field of view (FOV) = 20.48 cm. Plain radiograph findings and MRI findings of patients were compared.
  
  
  RESULTS
  In three of the patients with suspected early RA (N = 7), early RA was evaluated based on STIR images. All RA patients showed morphologic or signal intensity changes that allowed an evaluation of RA from MR findings. Four of five RA patients showed high signal intensity on STIR images in the wrist, proximal interphalangeal (PIP) joint, or metacarpophalangeal (MCP) joint that suggested synovitis. Multiple erosions in the hand and wrist were seen in four RA patients, with low signal intensity on T1-weighted images.
  
  
  CONCLUSIONS
  RA was correctly evaluated, and early RA could be identified with the compact MRI system. However, the current system has limitations, such as the nonselective STIR sequence used and magnetic field inhomogeneity.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. hyoshioka@partners.org
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshioka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ito
authors.forename: Shinya
authors.initials: S
authors.lastname: Handa
authors.forename: Sadanori
authors.initials: S
authors.lastname: Tomiha
authors.forename: Katsumi
authors.initials: K
authors.lastname: Kose
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Haishi
authors.forename: Akito
authors.initials: A
authors.lastname: Tsutsumi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Sumida
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D005240:Feasibility Studies; D005260:Female; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D014953:Wrist