title: Fluoride's effect on human dentin ultrasound velocity (elastic modulus) and tubule size.
abstract: Despite fluoride (F) use in caries prevention, not much is known about its effects on tooth quality. This study evaluated the effect of tooth F concentration ([F]) on selected dentin structural and mechanical properties. Third molars (n = 136) from Toronto, which has 1 part per million (p.p.m.) water [F], Montreal (0.2 p.p.m. water [F]), and Fortaleza (Brazil) (0.7 p.p.m. water [F]), were analyzed for [F], dental fluorosis (DF) severity, ultrasound velocity, and dentin tubule size and density. The enamel [F] was found to vary between 32 and 940 p.p.m., the dentin [F] was found to vary between 110 and 860 p.p.m., while the DF severity varied between TF0 and TF4. The enamel [F] showed no correlation with dentin [F], DF severity, ultrasound velocity, dentin tubule size or density. The dentin [F] correlated with DF severity, dentin tubule size, and ultrasound velocity. DF severity showed a correlation with dentin [F] and ultrasound velocity. It was concluded that dentin [F] is an indicator of dentin structural properties (dentin tubule size and ultrasound velocity), while DF severity is an indicator of dentin mechanical properties (ultrasound velocity).
authors.affiliation: Faculty of Dentistry, University of Toronto, Toronto, Canada.
authors.forename: Anya P G F
authors.initials: AP
authors.lastname: Vieira
authors.forename: Ron
authors.initials: R
authors.lastname: Hancock
authors.forename: Mircea
authors.initials: M
authors.lastname: Dumitriu
authors.forename: Hardy
authors.initials: H
authors.lastname: Limeback
authors.forename: Marc D
authors.initials: MD
authors.lastname: Grynpas
mesh_terms: D000704:Analysis of Variance; D001938:Brazil; D003743:Dental Enamel / Q000737:chemistry / Q000000981:diagnostic imaging; D003804:Dentin / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000187:drug effects* / Q000648:ultrastructure; D004548:Elasticity; D005457:Fluoridation; D005459:Fluorides / Q000032:analysis / Q000494:pharmacology*; D009050:Fluorosis, Dental / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008964:Molar, Third / Q000737:chemistry / Q000000981:diagnostic imaging / Q000648:ultrastructure; D009501:Neutron Activation Analysis; D009864:Ontario; D011792:Quebec; D014463:Ultrasonography; D014732:Vibration
chemical_list: D005459:Fluorides