title: Subendometrial arterial spectral doppler assessment during IVF cycles and its correlation with treatment outcome.
abstract: The influence of blood flow impedance in subendometrial arteries on embryo implantation rate was investigated by transvaginal sonographic examination in in vitro fertilization (IVF) cycles. A total of 39 women undergoing IVF treatment were evaluated along the treatment cycle. Power and spectral Doppler studies of subendometrial arteries were performed to calculate the pulsatility index (PI), resistance index (RI) and systolic:diastolic ratio (S:D). The correlation between these parameters and pregnancy achievement was analyzed. Patients were grouped according to whether pregnancy was achieved or not. RI and S:D did not differ between the groups along the course of treatment. In pregnant patients, the PI was significantly lower in the beginning of the cycle than on the preovulation day and ovum pickup day. PI in the beginning of the treatment was significantly lower in pregnancy cycles than in nonpregnancy ones. A lower PI on day 1 was correlated with a better chance for pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Ultrasound Unit and IVF Unit, Bnai-Zion Medical Center, Haifa, Israel.
authors.forename: Roman
authors.initials: R
authors.lastname: Gorokhovsky
authors.forename: Joseph
authors.initials: J
authors.lastname: Tal
authors.forename: Zvi
authors.initials: Z
authors.lastname: Leibovitz
authors.forename: Simon
authors.initials: S
authors.lastname: Degani
authors.forename: Israel
authors.initials: I
authors.lastname: Shapiro
authors.forename: Ilan
authors.initials: I
authors.lastname: Calderon
authors.forename: Yoav
authors.initials: Y
authors.lastname: Paltiely
authors.forename: Gonen
authors.initials: G
authors.lastname: Ohel
mesh_terms: D000328:Adult; D001158:Arteries; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D010064:Embryo Implantation; D004717:Endometrium / Q000098:blood supply / Q000000981:diagnostic imaging; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D009865:Oocytes; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D011673:Pulsatile Flow; D018608:Ultrasonography, Doppler / Q000379:methods*; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging; D014655:Vascular Resistance / Q000502:physiology