Palladium-catalyzed intramolecular N-arylation of heteroarenes: a novel and efficient route to benzimidazo[1,2-a]quinolines.
An efficient new route for the synthesis of benzimidazo[1,2-a]quinolines has been developed via the palladium-catalyzed intramolecular Buchwald-Harwtig aryl amination of newly synthesized 2-(2'-bromoanilino)quinolines.
Venkatesh
C
C
Department of Chemistry, Indian Institute of Technology, Kanpur-208016, India.
Sundaram
G S M
GS
Ila
H
H
Junjappa
H
H
D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007546:Isoquinolines / Q000138:chemical synthesis / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D012997:Solvents; D013696:Temperature
D001562:Benzimidazoles; D007546:Isoquinolines; D008024:Ligands; D012997:Solvents; C427107:benzimidazo(2,1-a)isoquinoline; D010165:Palladium