Heterotopic pregnancy following ovulation induction by clomiphene citrate and timed intercourse: a case report.
We report a combined intra-uterine and unruptured tubal pregnancy following ovulation induction by clomiphene citrate (CC) and timed intercourse. The diagnosis of heterotopic pregnancy (HP) is the major problem until occurrence of tubal rupture. Because HP is a life-threatening condition, the diagnosis should be made as soon as possible. In a spontaneous conception, HP is a rare event. The risk of HP significantly increases after ovulation induction. Clomiphene itself could be associated with a high HP rate. We present a case with normally developing intra-uterine singleton pregnancy successfully managed by salpingectomy of synchronous tubal pregnancy following ovulation induction by CC and a review of the literature.
Naki
M Murat
MM
Department of Obstetrics and Gynecology, Göztepe Research and Training Hospital, Istanbul, Turkey. mmuratnaki@yahoo.com
Tekcan
Cevahir
C
Uysal
Arzu
A
Güzin
Kadir
K
Yücel
Neşe
N
D000328:Adult; D002996:Clomiphene / Q000009:adverse effects*; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D006801:Humans; D010062:Ovulation Induction / Q000009:adverse effects* / Q000379:methods; D011247:Pregnancy; D011256:Pregnancy Outcome; D011274:Pregnancy, Tubal / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery
D005300:Fertility Agents, Female; D002996:Clomiphene