title: [Acute renal failure following mucosal administration of povidone iodine].
abstract: BACKGROUND
  Povidone iodine is a widely-used antiseptic agent, especially for cutaneous lesions. Despite its apparent innocuousness, some cases of acute renal failure are reportedly due to iodine toxicity.
  
  
  METHODS
  We report a case of an acute renal failure secondary to povidone iodine exposure in a 37-year-old woman. She underwent a hysteroscopy for diagnosis of primary sterility, and povidone iodine was used as the contrast agent. She developed acute renal failure with oliguria during the postoperative period. Treatment with diuretics and hemodialysis led to a favorable outcome and return of normal kidney function.
  
  
  CONCLUSIONS
  Mucosal administration of povidone iodine appears to lead to greater iodine toxicity than cutaneous administration. The clinical feature of our patient suggested tubular necrosis caused by iodine, after the other possible causes of acute renal failure were ruled out.
  
  
  CONCLUSIONS
  Acute renal failure secondary to povidone iodine administration is possible, especially through mucosal surfaces. Outcome is favorable after the conclusion of exposure and symptomatic treatment.
authors.affiliation: Service de néphrologie et de médecine interne, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Soumaya
authors.initials: S
authors.lastname: Béji
authors.forename: Hayet
authors.initials: H
authors.lastname: Kaaroud
authors.forename: Fatma
authors.initials: F
authors.lastname: Ben Moussa
authors.forename: Ezzedine
authors.initials: E
authors.lastname: Abderrahim
authors.forename: Souheil
authors.initials: S
authors.lastname: Zghidi
authors.forename: Fethi
authors.initials: F
authors.lastname: Ben Hamida
authors.forename: Hédi
authors.initials: H
authors.lastname: Ben Maiz
authors.forename: Adel
authors.initials: A
authors.lastname: Kheder
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000009:adverse effects*; D003287:Contrast Media / Q000009:adverse effects*; D004232:Diuretics / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005665:Furosemide / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015907:Hysteroscopy; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000009:adverse effects*; D006435:Renal Dialysis; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D003287:Contrast Media; D004232:Diuretics; D005665:Furosemide; D011206:Povidone-Iodine