Mastocytosis: the great masquerader.
Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.
Kong
James S W
JS
Division of Rheumaotology, Allergy, and Clinical Immunology, Department of Internal Medicine, University of California at Davis, Davis, CA, USA.
Teuber
Suzanne
S
Hallett
Rosemary
R
Gershwin
M Eric
ME
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000502:physiology; D008415:Mastocytosis / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D014581:Urticaria / Q000175:diagnosis*