title: Chronic progressive autonomic dysfunction in a dog.
abstract: A 3.5-year-old intact male American Pit Bull was presented because of urinary incontinence and dysuria. Constipation, followed by diarrhoea, ocular disturbances and finally regurgitation developed over the next 4 years. Autonomic dysfunction was evidenced by clinical presentation, as well as positive ophthalmic pilocarpine test and subnormal Schirmer tear test. Diagnosis, however, was established through histopathological and immunohistochemical examination. Lesions attributable to inflammatory degenerative neuropathy of the autonomic ganglia, which represents one of the various types of human autonomic failure, were detected.
authors.affiliation: Companion Animal Clinic (Medicine), Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 11 St. Voutyra str., GR-54 627, Thessaloniki, Greece. kadamama@vet.auth.gr
authors.forename: K K
authors.initials: KK
authors.lastname: Adamama-Moraitou
authors.forename: G D
authors.initials: GD
authors.lastname: Brellou
authors.forename: T S
authors.initials: TS
authors.lastname: Rallis
authors.forename: N
authors.initials: N
authors.lastname: Zavros
authors.forename: D
authors.initials: D
authors.lastname: Pardali
authors.forename: A
authors.initials: A
authors.lastname: Dinopoulos
authors.forename: I
authors.initials: I
authors.lastname: Vlemmas
mesh_terms: D000818:Animals; D001342:Autonomic Nervous System Diseases / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D008297:Male; D011379:Prognosis; D013997:Time Factors