Mycobacterium marinum, a further infectious agent associated with sarcoidosis: the polyetiology hypothesis.
A 39-y-old male had a diagnosis of sarcoidosis and corticosteroid therapy was started. Surprisingly, following his discharge from hospital, Mycobacterium marinum was isolated in 1 of 3 sputum samples taken 7 weeks earlier on admission. After this, Mycobacterium marinum-DNA was identified in the stored lung biopsies by the PCR-RFLP of the hsp65 gene.
Moling
Oswald
O
Division of Infectious Diseases, Ospedale Generale, Bolzano, Italy. molosw@hotmail.com
Sechi
Leonardo A
LA
Zanetti
Stefania
S
Seebacher
Christine
C
Rossi
Patrizia
P
Rimenti
Giovanni
G
Pagani
Leonardo
L
Vedovelli
Claudio
C
D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics; D018834:Chaperonin 60; D018833:Chaperonins / Q000235:genetics; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000175:diagnosis; D019910:Mycobacterium marinum / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D012507:Sarcoidosis / Q000209:etiology* / Q000382:microbiology
D001426:Bacterial Proteins; D018834:Chaperonin 60; C074119:heat-shock protein 65, Mycobacterium; D018833:Chaperonins