[Perioperative use of beta-blockers in noncardiac surgery].
A variety of strategies have been used to reduce the high prevalence and mortality rates of cardiac complications in patients undergoing noncardiac surgery. One approach taken is to prescribe agents that block beta-adrenergic receptors. The effect of beta-blockers on myocardial ischemia is multifactorial: they correct myocardial oxygen imbalance, prevent rupture of atheromatous plaque, and reduce coronary vasoconstriction. We summarize the results of several recently published studies that confirm the beneficial effects and the low incidence of side effects.
Cruz Pardos
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P
Servicio de Anestesiología, Reanimación y Tratamiento del Dolor, Hospital General Universitario Gregorio Marañón, Madrid. triciacp@eresmas.com
Fernańdez Riveira
C
C
Garutti
I
I
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000517:prevention & control; D050197:Atherosclerosis / Q000188:drug therapy; D002986:Clinical Trials as Topic; D000075202:Contraindications; D019317:Evidence-Based Medicine; D006331:Heart Diseases / Q000517:prevention & control*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007431:Intraoperative Complications / Q000517:prevention & control*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control*; D011229:Preanesthetic Medication; D012308:Risk Management; D012422:Rupture, Spontaneous; D013514:Surgical Procedures, Operative
D000319:Adrenergic beta-Antagonists