Randomised controlled trial of combined paracetamol and ibuprofen for fever.
A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.
Erlewyn-Lajeunesse
M D S
MD
Clinical Sciences at South Bristol, Faculty of Medicine, University of Bristol, UK. Mich.Lajeunesse@bristol.ac.uk
Coppens
K
K
Hunt
L P
LP
Chinnick
P J
PJ
Davies
P
P
Higginson
I M
IM
Benger
J R
JR
D000082:Acetaminophen / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004630:Emergencies; D005260:Female; D005334:Fever / Q000188:drug therapy*; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D007052:Ibuprofen