title: Innate immunity and the pneumococcus.
abstract: The innate immune system provides a non-specific first line of defence against microbes and is crucial both in the development and effector stages of subsequent adaptive immune responses. Consistent with its importance, study of the innate immune system is a broad and fast-moving field. Here we provide an overview of the recent key advances made in this area with relation to the important pathogen Streptococcus pneumoniae (the pneumococcus).
authors.affiliation: Division of Infection and Immunity, University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: Gavin K
authors.initials: GK
authors.lastname: Paterson
authors.affiliation: Division of Infection and Immunity, University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: Tim J
authors.initials: TJ
authors.lastname: Mitchell
mesh_terms: D006801:Humans; D007113:Immunity, Innate / Q000502:physiology*; D011008:Pneumococcal Infections / Q000276:immunology* / Q000382:microbiology / Q000401:mortality / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D013296:Streptococcus pneumoniae; D051193:Toll-Like Receptors / Q000502:physiology
chemical_list: D022242:Pneumococcal Vaccines; D051193:Toll-Like Receptors