title: GIST: a clinical dilemma.
abstract: The authors report a clinical case of malignant gastric and duodenojejunal GIST, in which the only surgical treatment seems to be definitive. In a 69-year-old female, a surgical resection of the gastric and duodenojejunal tumor was performed. Histological analysis showed two spindle cells stromal tumors with mitotic rate >20/10 HPF and its uncommitted origin was demonstrated. Despite the high malignancy degree, the patient refused chemotherapy treatment and there were no local recurrence nor metastasis at a follow-up of 8 years. For this reason and because of the uncertain behavior of histologically benign GIST, the authors propose a lifelong follow-up of all patients managed with potentially curative surgical resection.
authors.affiliation: Dipartimento Chirurgico, Materno-Infantile e di Scienze dell'lmmagine, Sezione di Semeiotica Chirurgica, Università degli Studi di Cagliari.
authors.forename: A
authors.initials: A
authors.lastname: Pisanu
authors.forename: N
authors.initials: N
authors.lastname: Cillara
authors.forename: A
authors.initials: A
authors.lastname: Montisci
authors.forename: P
authors.initials: P
authors.lastname: Ongetta
authors.forename: A
authors.initials: A
authors.lastname: Uccheddu
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans