Bisphosphonate-related osteonecrosis of the jaws.
The purpose of this paper is to highlight an emerging phenomenon of osteonecrosis of the jaws that occurs in some patients who are on long-term bisphosphonate therapy. The condition can appear spontaneously or as a result of trauma, and is difficult to treat. Dental surgeons must be aware of patients who are at risk and institute appropriate preventive care. It is also important to recognize the condition when it does appear and refer appropriately. We present the first local case series of the condition showing varied clinical presentations and treatments.
Yeo
Aidan Choon-Poh
AC
Department of Oral and Maxillofacial Surgery, National Dental Centre, Singapore. a-yeo@rocketmail.com
Lye
Kok-Weng
KW
Poon
Choy-Yoke
CY
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000139:chemically induced / Q000628:therapy; D008439:Maxillary Diseases / Q000139:chemically induced / Q000628:therapy; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced* / Q000628:therapy; D014081:Tooth Extraction / Q000009:adverse effects
D000970:Antineoplastic Agents; D050071:Bone Density Conservation Agents; D004164:Diphosphonates