title: Alkaloids from Daphniphyllum longeracemosum.
abstract: Four new Daphniphyllum alkaloids, daphnilongeranins A-D (1-4), along with four known ones, daphniphylline, longistylumphylline A, deoxyisocalyciphylline B, and daphnicyclidin D, were isolated from the leaves and stems of Daphniphyllum longeracemosum. Daphnilongeranin A (1) is the first seco-10,17-longistylumphylline A type Daphniphyllum alkaloid, and daphnilongeranin B (2) is a new C-22 nor-Daphniphyllum alkaloid based on a new C21 skeleton. Their structures and stereochemistry were determined using spectroscopic data and chemical methods.
authors.affiliation: State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, People's Republic of China.
authors.forename: Sheng-Ping
authors.initials: SP
authors.lastname: Yang
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Chuan-Rui
authors.initials: CR
authors.lastname: Zhang
authors.forename: Hua-Dong
authors.initials: HD
authors.lastname: Cheng
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Yue
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal