title: Lethal subarachnoid bleeding under immunosuppressive therapy due to mycotic arteritis.
abstract: A subarachnoid haemorrhage (SAH) occurred 67 days after cardiac transplantation in a 10-year-old girl with consecutive immunocompromising therapy. Neither digital subtraction angiography (DSA) nor computed tomographic angiography showed signs of intracranial vascular malformations. One month before the lethal SAH occurred, she had developed arterial hypertension and attacks of severe headache with cerebrospinal fluid (CSF) pleocytosis while CT scans showed an infarct of the left thalamus. Pathologic findings established the rare diagnosis of SAH due to aspergillosis-related mycotic arteritis. Imaging characteristics are presented.
authors.affiliation: Department of Clinical Radiology, University Hospital of Muenster, Albert-Schweitzer-Strasse 33, 48149 Münster, Germany. weigels@uni-muenster.de
authors.forename: Stefanie
authors.initials: S
authors.lastname: Weigel
authors.forename: Stephan
authors.initials: S
authors.lastname: Kloska
authors.forename: Hans Gerd
authors.initials: HG
authors.lastname: Kehl
authors.forename: Michael
authors.initials: M
authors.lastname: Freund
mesh_terms: D000792:Angiography; D015901:Angiography, Digital Subtraction; D001167:Arteritis / Q000382:microbiology*; D001228:Aspergillosis / Q000150:complications*; D002539:Cerebral Arterial Diseases / Q000382:microbiology*; D002544:Cerebral Infarction / Q000382:microbiology; D002648:Child; D017809:Fatal Outcome; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D013345:Subarachnoid Hemorrhage / Q000209:etiology*; D013788:Thalamus / Q000098:blood supply; D014057:Tomography, X-Ray Computed
chemical_list: D007166:Immunosuppressive Agents