title: Poststroke fatigue: course and its relation to personal and stroke-related factors.
abstract: OBJECTIVE
  To describe the course of fatigue during the first year poststroke and to determine the relation between fatigue at 1 year poststroke and personal characteristics, stroke characteristics, and poststroke impairments.
  
  
  METHODS
  Inception cohort.
  
  
  METHODS
  Rehabilitation center.
  
  
  METHODS
  Patients (N=167) with a first-ever supratentorial stroke admitted for inpatient rehabilitation.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  The Fatigue Severity Scale measured the presence and impact of fatigue at admittance for inpatient rehabilitation, as well as at 6 months and 1 year poststroke.
  
  
  RESULTS
  At admission, 6 months and 1 year poststroke, fatigue was present in 51.5%, 64.1%, and 69.5% of the patients, respectively. Fatigue impact 1 year poststroke was greater among patients with more depressive symptoms, higher age, women, and patients with a locus of control more directed to powerful others.
  
  
  CONCLUSIONS
  Because fatigue impact is an increasing problem during the first year poststroke, it deserves more attention in clinical practice and scientific research. Locus of control and depression are related to poststroke fatigue and might be important foci for future interventions.
authors.affiliation: Center of Excellence for Rehabilitation Medicine Utrecht, Rehabilitation Center De Hoogstraat, The Netherlands. V.Schepers@dehoogstraat.nl
authors.forename: Vera P
authors.initials: VP
authors.lastname: Schepers
authors.forename: Anne M
authors.initials: AM
authors.lastname: Visser-Meily
authors.forename: Marjolijn
authors.initials: M
authors.lastname: Ketelaar
authors.forename: Eline
authors.initials: E
authors.lastname: Lindeman
mesh_terms: D000367:Age Factors; D003863:Depression / Q000150:complications; D005221:Fatigue / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D007389:Internal-External Control; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D012737:Sex Factors; D020521:Stroke / Q000150:complications* / Q000523:psychology; D000071939:Stroke Rehabilitation