A case of suspected non-neurosurgical adult fatal propofol infusion syndrome.
A previously healthy woman (20 years old) was admitted to our hospital with several fractures after a car accident. She was sedated with propofol, etc. in doses ranging from 1.4 to 5.1 mg/kg/h for 88 h. She developed multiple organ failure with rhabdomyolysis and died. This case fulfils (except acidosis) the criteria of propofol-infusion syndrome (PRIS) in a young adult.
Eriksen
J
J
Department of Anesthesia, Holstebro Hospital, Holstebro, Denmark. j@eriksen.mail.dk
Povey
H M R
HM
D000293:Adolescent; D018686:Anesthetics, Intravenous / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007262:Infusions, Intravenous; D009102:Multiple Organ Failure / Q000139:chemically induced*; D015742:Propofol / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D013577:Syndrome
D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D015742:Propofol