Erythromelanosis follicularis faciei et colli associated with keratosis pilaris in two brothers.
Erythromelanosis follicularis faciei et colli is characterized by well-demarcated erythema, hyperpigmentation, and follicular papules. Since the original description, it has seldom been reported in the literature. We present two adolescent brothers who had this disorder associated with keratosis pilaris on the shoulders and the extensor surfaces of the arms. Dermatologic examination found brown-red pigmentation, erythema, and follicular papules on both maxillary, preauricular regions, and the cheeks. The lesions of the older brother were more prominent. Histopathologic examination of skin biopsy specimens taken from both brothers revealed hyperpigmentation of the basal layer, follicular plugging, dermal vascular dilatation and congestion, and perivascular inflammatory infiltration. We suggest that the coexistence of these two conditions in brothers implies a genetic inheritance and a possible relationship between the disorders.
Ermertcan
Aylin Türel
AT
Department of Dermatology, Medical Faculty of Celal Bayar University, Manisa, Turkey. draylinturel@hotmail.com
Oztürkcan
Serap
S
Sahin
Mustafa Turhan
MT
Türkdogan
Peyker
P
Saçar
Tuncer
T
D000293:Adolescent; D001707:Biopsy, Needle; D007644:Darier Disease / Q000150:complications / Q000235:genetics / Q000473:pathology*; D004890:Erythema / Q000150:complications / Q000235:genetics / Q000473:pathology; D005148:Facial Dermatoses / Q000150:complications / Q000235:genetics / Q000473:pathology; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D017495:Hyperpigmentation / Q000150:complications / Q000235:genetics / Q000473:pathology*; D007150:Immunohistochemistry; D008297:Male; D008548:Melanosis / Q000150:complications / Q000235:genetics / Q000473:pathology*; D010375:Pedigree; D035583:Rare Diseases; D035781:Siblings