title: Comparison of accuracy of 64-slice cardiovascular computed tomography with coronary angiography in patients with suspected coronary artery disease.
abstract: Cardiovascular computed tomography (CVCT) with the recently released 64-slice technology increases spatial resolution and decreases acquisition times and slice thickness. We investigated the accuracy of 64-slice CVCT in relation to catheter angiography. We studied 66 sequential subjects who underwent 64-slice CVCT and catheter angiography within 30 days. Accuracy results were 94% for interpretable images, 95% for sensitivity, 96% for specificity, 97% for positive predictive value, and 92% for negative predictive value for lesions with >50% stenosis. We found 100% agreement between 64-slice CVCT and catheterization among vein graft evaluations (9 of 9). These metrics are vastly improved from the 16-slice generation and support 64-slice CVCT as a reliable diagnostic tool.
authors.affiliation: The Department of Investigator Initiated Research, South Carolina Heart Center, Columbia, South Carolina, USA. jfine@scheart.com
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Fine
authors.forename: Christie B
authors.initials: CB
authors.lastname: Hopkins
authors.forename: Nicol
authors.initials: N
authors.lastname: Ruff
authors.forename: F Carter
authors.initials: FC
authors.lastname: Newton
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*