title: Isolation of a Plasmodium vivax refractory Anopheles culicifacies strain from India.
abstract: Anopheles culicifaciessensu lato comprises five sibling species. We report the isolation of an An. culicifacies species B strain which is completely refractory to Plasmodium vivax sporogonic development and partially refractory to P. falciparum. Parasite development in this strain is arrested by a melanotic encapsulation mechanism in the mid-gut. We compare the infectivity of this refractory strain and four other species B strains from different epidemiological zones of India with P. vivax in the laboratory.
authors.affiliation: National Institute of Malaria Research, Delhi, India. adak.mrc@gmail.com
authors.forename: T
authors.initials: T
authors.lastname: Adak
authors.forename: O P
authors.initials: OP
authors.lastname: Singh
authors.forename: Nutan
authors.initials: N
authors.lastname: Nanda
authors.forename: V P
authors.initials: VP
authors.lastname: Sharma
authors.forename: Sarala K
authors.initials: SK
authors.lastname: Subbarao
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D005260:Female; D041981:Gastrointestinal Tract / Q000469:parasitology; D006801:Humans; D007194:India / Q000453:epidemiology; D007303:Insect Vectors / Q000469:parasitology*; D008288:Malaria / Q000453:epidemiology* / Q000635:transmission; D016778:Malaria, Falciparum / Q000453:epidemiology / Q000635:transmission; D016780:Malaria, Vivax / Q000453:epidemiology / Q000635:transmission; D033661:Oocysts / Q000302:isolation & purification; D010963:Plasmodium falciparum / Q000502:physiology; D010966:Plasmodium vivax / Q000472:pathogenicity / Q000502:physiology*; D013045:Species Specificity; D033761:Spores, Protozoan / Q000502:physiology