title: [Minimally invasive esophagectomy: prospective evaluation of laparoscopic gastric mobilization].
abstract: OBJECTIVE
  Esophagectomy carries high morbidity, mainly due to respiratory complications. In digestive surgery, postoperative outcome is generally improved by minimally invasive surgery. A prospective study was conducted to evaluate feasibility and postoperative outcome of minimally invasive esophagectomy (MIE).
  
  
  METHODS
  From July 2001 to June 2004, 20 patients underwent esophagectomy with laparoscopic gastric mobilization (LGM) for squamous cell carcinoma (N=11), adenocarcinoma (N=7), Barrett's esophagus with high-grade dysplasia (N=1), and long peptic stricture (N=1). Tumours (N=19) were located on the cardia (N=5), on the lower third of the oesophagus (N=10), on the median third (N=3), and on the upper third (N=1). Following LGM, transthoracic (N=19) or transhiatal (N=1) oesophagectomy was performed.
  
  
  RESULTS
  Complete LGM was achieved in all cases. Mean operative time for LGM was 197+/-48 minutes. In the 19 patients operated for tumours, 18 underwent R0 resection. Eleven patients (55%) developed postoperative complications, mainly (30%) respiratory. Intrathoracic anastomotic leakage occurred in 2 patients, with favourable outcome. Pylorospasm (N=1) was the only intraabdominal complication. One patient died (5%).
  
  
  CONCLUSIONS
  Esophagectomy with LGM is feasible with few specific complications. However, no decrease in morbidity could be observed with this technique. Further studies are required to evaluate if thoracoscopy could improve the postoperative course after LGM and to validate oncologic safety of MIE.
authors.affiliation: Service de Chirurgie Générale, Digestive et Endocrinienne, Hôpital Universitaire Saint-Louis, APHP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Godiris-Petit
authors.forename: N
authors.initials: N
authors.lastname: Munoz-Bongrand
authors.forename: I
authors.initials: I
authors.lastname: Honigman
authors.forename: P
authors.initials: P
authors.lastname: Cattan
authors.forename: E
authors.initials: E
authors.lastname: Sarfati
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000328:Adult; D000368:Aged; D001471:Barrett Esophagus / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects / Q000379:methods*; D004938:Esophageal Neoplasms / Q000601:surgery; D016629:Esophagectomy / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies