Phaeohyphomycosis: an unusual pituitary mass.
A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection consistent with phaeohyphomycosis. Development of this lesion is probably attributed to allergic rhinitis and insulin-dependent diabetes mellitus. Intravenous amphotericin and itraconazole treatment resulted in full recovery and the patient remains well at 6-month postoperative follow-up.
Yeung
I Y L
IY
Department of Neurosurgery, Hammersmith Hospital, UK.
Whitelaw
B C
BC
Hortobágyi
T
T
Bódi
I
I
Petrou
M A
MA
Connor
S E J
SE
Thomas
N W M
NW
D020314:Central Nervous System Fungal Infections / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010900:Pituitary Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013101:Sphenoid Sinus / Q000473:pathology