title: Palladium-catalyzed arylation and heteroarylation of azolopyrimidines.
abstract: A comparative study of the palladium-catalyzed arylation and heteroarylation of 5-bromoazolopyrimidines shows that aryl and electron-rich heteroaryl boronic acids gave higher yields than those obtained using the corresponding aryl and heteroaryl tributyl stannanes. In contrast, the reaction with electron-poor heteroaryl tributyl stannanes gave better results than the corresponding boronic acids.
authors.affiliation: Departamento de Química Orgánica, Universidad de Alcalá, 28871-Alcalá de Henares, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Mendiola
authors.forename: Isabel
authors.initials: I
authors.lastname: Castellote
authors.forename: Julio
authors.initials: J
authors.lastname: Alvarez-Builla
authors.forename: Javier
authors.initials: J
authors.lastname: Fernández-Gadea
authors.forename: Antonio
authors.initials: A
authors.lastname: Gómez
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Vaquero
mesh_terms: D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D001897:Boronic Acids; D011743:Pyrimidines; D010165:Palladium; C030986:pyrimidine