Identification of Cpgp40/15 Type Ib as the predominant allele in isolates of Cryptosporidium spp. from a waterborne outbreak of gastroenteritis in South Burgundy, France.
Cryptosporidium sp. isolates from a waterborne outbreak of diarrhea in France were analyzed by PCR-restriction fragment length polymorphism analysis and sequencing of the Cpgp40/15 locus. Ninety-one percent of the isolates were Cryptosporidium hominis type Ib. The results of this study and those of studies of other outbreaks suggest that the type Ib allele is the predominant allele associated with waterborne cryptosporidiosis.
Cohen
Seth
S
Division of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Boston, MA 02111, USA.
Dalle
Frédéric
F
Gallay
Anne
A
Di Palma
Marc
M
Bonnin
Alain
A
Ward
Honorine D
HD
D000483:Alleles; D000818:Animals; D003457:Cryptosporidiosis / Q000453:epidemiology / Q000469:parasitology; D003458:Cryptosporidium / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016054:DNA, Protozoan / Q000032:analysis; D004196:Disease Outbreaks; D005602:France / Q000453:epidemiology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000469:parasitology; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D015800:Protozoan Proteins / Q000235:genetics* / Q000378:metabolism; D017422:Sequence Analysis, DNA; D014867:Water / Q000469:parasitology*
C451425:Cpgp40-15 protein, Cryptosporidium parvum; D016054:DNA, Protozoan; D015800:Protozoan Proteins; D014867:Water