[Investigation into microcirculation in the vascular bed of healthy people and patients at rest and during the LBNP test].
Computer capillaroscopy during the lower body pressure test (LBNP) provided additional information about the effects of orthostasis on blood microcirculation and separate estimation of blood velocity in arterial, intermediate and venous segments of capillaries. Microcirculation was demonstrated to be sensitive to the LBNP exposure as in healthy volunteered subjects, so in ischemic, including hypertensive, patients. The highest velocity of capillary blood and the lowest Kv were determined in ischemic patients including hypertensive, in whom venous velocity in capillaries prevailed over arterial (Kv < 1), whereas in healthy subjects Kv never fell below 1. 09. Results of the comparative investigations of blood microcirculation in healthy people and patients with various cardiovascular problems can be used in clinical and space medicine for assessment of the CVS functioning and orthostatic tolerance.
Mikhaĭlov
V M
VM
Gurfinkel'
Iu I
IuI
Kudutkina
M I
MI
Ushakov
B B
BB
D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D002196:Capillaries / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008150:Lower Body Negative Pressure; D008297:Male; D008833:Microcirculation / Q000502:physiology; D020678:Microscopic Angioscopy; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology*; D009262:Nails / Q000098:blood supply*