title: Application of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis complex isolates.
abstract: The usefulness of a low-tech rapid test for culture confirmation of Mycobacterium tuberculosis complex, Capilia TB, was tested on 172 mycobacteria-positive clinical samples. The overall sensitivity and specificity were 92.4% and 100%, respectively. In three of nine false-negative isolates a mutation in the mpb64 gene could be detected.
authors.affiliation: National Reference Center for Mycobacteria, Forschungszentrum Borstel, Borstel, Germany. dhillemann@fz-borstel.de
authors.forename: D
authors.initials: D
authors.lastname: Hillemann
authors.forename: S
authors.initials: S
authors.lastname: Rüsch-Gerdes
authors.forename: E
authors.initials: E
authors.lastname: Richter
mesh_terms: D002845:Chromatography / Q000379:methods*; D005060:Europe; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012680:Sensitivity and Specificity