Intra-abdominal desmoid tumor following retroperitoneal lymph node dissection for testicular germ cell tumor.
In the testicular cancer post-treatment setting a rapidly growing retroperitoneal mass leads to a differential diagnosis including recurrent germ cell tumor, residual mature teratoma, or sarcomatoid degeneration. We report the case of a 27-year-old man with a large abdominal mass occurring in the setting of a mixed germ cell tumor after radical orchiectomy with primary chemotherapy followed by retroperitoneal lymph node dissection. Surgical excision of this mass followed by pathological review revealed an intra-abdominal desmoid tumor. Fluorescence in situ hybridization (FISH) for isochromosome 12p failed to demonstrate a germ cell tumor origin. This is the fourth such case of an intra-abdominal desmoid tumor after retroperitoneal lymph node dissection for testicular cancer in the urologic literature. This case highlights the need for careful consideration of a desmoid tumor when a rapidly growing spindle cell tumor is encountered in a post-treatment testis cancer patient.
Lawatsch
Eric J
EJ
Department of Urology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Datta
Milton W
MW
Van Tuinen
Peter
P
Sudakoff
Gary S
GS
Davis
Nancy B
NB
Langenstroer
Peter
P
D000008:Abdominal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D018222:Desmoid Tumors / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007813:Laparotomy; D008197:Lymph Node Excision; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000601:surgery*; D009919:Orchiectomy / Q000009:adverse effects; D012187:Retroperitoneal Space; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed