title: High-throughput screening for the asymmetric transformation reaction of L-histidine to D-histidine by capillary array electrophoresis.
abstract: Asymmetric transformation reaction of L-histidine to D-histidine was studied by homemade capillary array electrophoresis for the first time. The enantiomeric excess value of asymmetric histidine products can be directly determined from the electrophoretogram of capillary array electrophoresis. The experiment results showed that the optimized asymmetric transformation reaction condition was in the presence of salicylaldehyde as catalyst and acetic acid as solvent.
authors.affiliation: State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, PR China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Kaiying
authors.initials: K
authors.lastname: Liu
authors.forename: Guangming
authors.initials: G
authors.lastname: Sun
authors.forename: Jiling
authors.initials: J
authors.lastname: Bai
authors.forename: Li
authors.initials: L
authors.lastname: Wang
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D019075:Electrophoresis, Capillary / Q000295:instrumentation; D006639:Histidine / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; C013243:salicylaldehyde; D006639:Histidine