Chemical tools for activity-based proteomics.
Several approaches for proteome analysis and the generation of proteome subsets rely on engineered chemical probes that are tailored towards the detection of different protein classes. The concepts are presented in this review covering the literature until mid-2005.
Hagenstein
Miriam C
MC
Organic and Bioorganic Chemistry, Department of Chemistry, University of Bielefeld, Germany.
Sewald
Norbert
N
D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism; D005544:Forecasting; D020869:Gene Expression Profiling; D008024:Ligands; D015335:Molecular Probes; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D040901:Proteomics / Q000379:methods*
D004791:Enzyme Inhibitors; D008024:Ligands; D015335:Molecular Probes; D011506:Proteins