title: Erectile dysfunction associated with pregabalin add-on treatment in patients with partial seizures: five case reports.
abstract: Sexual dysfunction has been reported in both men and women with epilepsy. Associated factors are diverse but include, among others, antiepileptic drugs. We present the cases of 5 men who reported mild to moderate erectile dysfunction or impotence for the first time when treated with the new antiepileptic drug pregabalin as add-on therapy.
authors.affiliation: Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, Scotland, UK.
authors.forename: Nikolas
authors.initials: N
authors.lastname: Hitiris
authors.forename: Jeannette A
authors.initials: JA
authors.lastname: Barrett
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Brodie
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004828:Epilepsies, Partial / Q000188:drug therapy*; D007172:Erectile Dysfunction / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069583:Pregabalin; D016032:Randomized Controlled Trials as Topic; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid