[Acute renal failure following mucosal administration of povidone iodine].
BACKGROUND
Povidone iodine is a widely-used antiseptic agent, especially for cutaneous lesions. Despite its apparent innocuousness, some cases of acute renal failure are reportedly due to iodine toxicity.


METHODS
We report a case of an acute renal failure secondary to povidone iodine exposure in a 37-year-old woman. She underwent a hysteroscopy for diagnosis of primary sterility, and povidone iodine was used as the contrast agent. She developed acute renal failure with oliguria during the postoperative period. Treatment with diuretics and hemodialysis led to a favorable outcome and return of normal kidney function.


CONCLUSIONS
Mucosal administration of povidone iodine appears to lead to greater iodine toxicity than cutaneous administration. The clinical feature of our patient suggested tubular necrosis caused by iodine, after the other possible causes of acute renal failure were ruled out.


CONCLUSIONS
Acute renal failure secondary to povidone iodine administration is possible, especially through mucosal surfaces. Outcome is favorable after the conclusion of exposure and symptomatic treatment.
Béji
Soumaya
S
Service de néphrologie et de médecine interne, Hôpital Charles Nicolle, Tunis, Tunisie.
Kaaroud
Hayet
H
Ben Moussa
Fatma
F
Abderrahim
Ezzedine
E
Zghidi
Souheil
S
Ben Hamida
Fethi
F
Ben Maiz
Hédi
H
Kheder
Adel
A
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000009:adverse effects*; D003287:Contrast Media / Q000009:adverse effects*; D004232:Diuretics / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005665:Furosemide / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015907:Hysteroscopy; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000009:adverse effects*; D006435:Renal Dialysis; D013997:Time Factors; D016896:Treatment Outcome
D000891:Anti-Infective Agents, Local; D003287:Contrast Media; D004232:Diuretics; D005665:Furosemide; D011206:Povidone-Iodine