[Specific features of Helicobacter pylori infection and the character of immune response in patients with a severe course of duodenal ulcer].
The presence of genetic markers of vacA-positive strains with s1/s2 subtype (76%) with a high proportions (84%) of mixed genotype and detection in a breath air the ammonia at significantly high concentrations, have been found to be the specific features of H. pylori infection in patients with a severe course of duodenal ulcer. A low level of specific IgG antibodies, the growth of immunological inflammation markers and the depression of humoral immunity have been established.
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D000641:Ammonia / Q000032:analysis / Q000378:metabolism; D000907:Antibodies, Bacterial / Q000097:blood*; D001426:Bacterial Proteins / Q000235:genetics; D001944:Breath Tests; D004381:Duodenal Ulcer / Q000097:blood / Q000378:metabolism / Q000382:microbiology; D005819:Genetic Markers; D016481:Helicobacter Infections / Q000097:blood / Q000378:metabolism / Q000382:microbiology; D016480:Helicobacter pylori / Q000235:genetics* / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D011110:Polymorphism, Genetic; D013045:Species Specificity; D014774:Virulence; D037521:Virulence Factors / Q000235:genetics
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D005819:Genetic Markers; D007074:Immunoglobulin G; C074689:VacA protein, Helicobacter pylori; D037521:Virulence Factors; D000641:Ammonia