Prospective comparison of a new chromogenic medium, MRSASelect, to CHROMagar MRSA and mannitol-salt medium supplemented with oxacillin or cefoxitin for detection of methicillin-resistant Staphylococcus aureus.
MRSASelect agar was compared to CHROMagar, mannitol-salt agar with oxacillin, and mannitol-salt agar with cefoxitin (MSA-CFOX) for the isolation of methicillin-resistant Staphylococcus aureus (MRSA). The sensitivities and specificities were 97.3% and 99.8%, 82.9% and 99.1%, 80.2% and 79%, and 99.1% and 84.8%, respectively. MSA-CFOX and MRSASelect had a high sensitivity. MRSASelect, however, was more specific and proved to be a more reliable and rapid medium for the detection of MRSA.
Stoakes
Luba
L
Department of Clinical Microbiology and Infection Control, London Health Sciences Centre, Room E3-316, Westminster Tower, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada. zafar.hussain@lhsc.on.ca.
Reyes
Romina
R
Daniel
Janis
J
Lennox
Gwen
G
John
Michael A
MA
Lannigan
Robert
R
Hussain
Zafar
Z
D000362:Agar; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002440:Cefoxitin / Q000494:pharmacology; D002863:Chromogenic Compounds; D003470:Culture Media; D006801:Humans; D008353:Mannitol; D016106:Methicillin Resistance; D010068:Oxacillin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D002863:Chromogenic Compounds; D003470:Culture Media; D008353:Mannitol; D002440:Cefoxitin; D000362:Agar; D010068:Oxacillin