Intralesional corticosteroid injection vs surgical treatment of chalazia in pigmented patients.
OBJECTIVE
To compare the outcome of intralesional corticosteroid injection and surgical treatment of chalazia.


METHODS
An interventional comparative study.


METHODS
PNS Shifa, Naval Hospital, Karachi from 1st September 2002 to 31st August 2003.


METHODS
During a 9-month recruitment period all patients attending PNS Shifa, Naval Hospital, Karachi, for treatment of chalazia were inducted in the study. A 141 patients with chalazia completed the study. Patients received either incision-curettage (surgical treatment/ ST group) or intralesional corticosteroid injection treatment (steroid injection/ SI group). The same procedure was repeated in unsuccessful cases only once. Z-test of proportion was used as appropriate statistical test of significance at p <0.05 for the comparison of the results between the two groups.


RESULTS
The success was achieved in 59 out of 75 patients (79%) in ST group and 41 of 66 patients (62%) in SI group at first visit after two weeks (p-value <0.01). The success in ST group improved to 89% (67 out of 75 patients) after second operation and to 80% (53 out of 66 patients) in SI group after second injection of the steroid given at second week (p-value < 0.14).


CONCLUSIONS
Intralesional steroid injection is an effective and safe alternative procedure for the treatment of chalazia. The results are comparable to surgical treatment especially after second injection. It is not associated with any serious complications although skin depigmentation is relatively common in coloured population.
Ahmad
Salahuddin
S
Eye Department, PNS Shifa, Karachi. muzains7@hotmail.com
Baig
Mushtaq Ahmed
MA
Khan
Muhammad Azam
MA
Khan
Inam-ul-Haq
IU
Janjua
Teyyeb Azeem
TA
D000293:Adolescent; D000328:Adult; D000368:Aged; D017043:Chalazion / Q000188:drug therapy* / Q000601:surgery*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D012880:Skin Pigmentation; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage*
D005938:Glucocorticoids; D014221:Triamcinolone