Long-term outcome and quality of life after continent ileostomy.
BACKGROUND
This study was designed to evaluate long-term outcomes for patients undergoing Kock continent ileostomy, identify factors associated with adverse outcomes, and compare changes in quality of life after removal of the reservoir.


METHODS
The records of all patients (n = 330) undergoing continent ileostomy at the Cleveland Clinic Foundation between 1974 and 2001 were reviewed. Patient-related, intraoperative, and postoperative factors were evaluated as predictor variables of long-term pouch survival. Quality of life was evaluated using the continent ileostomy surgery follow-up questionnaire and the Cleveland Global Quality of Life scale (n = 216). These were compared between patients with continent ileostomy (n = 181) and patients who underwent removal of the continent ileostomy and conversion to an end stoma (n = 35).


RESULTS
The median patient follow-up was 11 (range, 1-27) years. The median revision-free pouch interval was 14 (95 percent confidence interval, 11-17) months. The 10-year and 20-year pouch survival was 87 and 77 percent, respectively. Patients had an average of 3.7(range, 1-28) complications and 2.9 (range, 1-27) pouch revisions during follow-up. On multivariate analysis, Crohn's disease (hazard ratio = 4.5), female gender (hazard ratio = 2.4), fistula development (hazard ratio = 3), and body mass index (hazard ratio = 2.4 per 5 unit increase) were independent predictors of pouch failure. Quality of life measurements for patients with a continent ileostomy were higher on all scales in comparison with patients who had the Kock reservoir and then reverted to a Brooke ileostomy.


CONCLUSIONS
Despite the associated morbidity with continent ileostomy surgery, long-term results and quality of life were encouraging. Continent ileostomy may be offered as an attractive long-term option to select patients whose only alternative is an end ileostomy.
Nessar
Gurel
G
Department of Colon and Rectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Fazio
Victor W
VW
Tekkis
Paris
P
Connor
Jason
J
Wu
James
J
Bast
Jane
J
Borkowski
Allison
A
Delaney
Conor P
CP
Remzi
Feza H
FH
D000293:Adolescent; D000328:Adult; D000368:Aged; D003108:Colonic Diseases / Q000601:surgery; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009820:Ohio; D017060:Patient Satisfaction; D016016:Proportional Hazards Models; D011788:Quality of Life; D012086:Reoperation; D011795:Surveys and Questionnaires; D016896:Treatment Outcome