[Genetic polymorphisms of 10 X chromosome STR loci in a Chinese Tibetan population].
OBJECTIVE
To investigate the alleles and genotypes frequency of 10 short tandem repeat (STR) loci on the X chromosome(DXS7423, DXS8378, DXS6799, DXS7424, DXS7130, DXS7132, DXS6789, DXS101, DXS6804, DXS7133) of Tibetan individuals living in Xizang Autonomous Region, Southwest China.


METHODS
The 10 X-chromosomal STR loci were analyzed with PCR, followed by polyacylamide gel electrophoresis and silver staining.


RESULTS
Among unrelated Tibetan individuals, the numbers of alleles in the 10 X-STR loci(DXS7423, DXS8378, DXS6799, DXS7424, DXS7130, DXS7132, DXS6789, DXS101, DXS6804, DXS7133) were 5, 5, 5, 9, 7, 7, 11, 9, 5 and 4, respectively. The genotype frequencies in females were in accordance with Hardy-Weinberg equilibrium.


CONCLUSIONS
The 10 X-chromosomal STRs loci are appropriate for individual identification, for paternity testing involving a female child, and for studies on related disease.
Gao
Ya
Y
The State Key Subject for Forensic Sciences, Key Laboratory of National Ministry of Health for Forensic Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R.China.
Jin
Tian-bo
TB
Yu
Bing
B
Du
Hong
H
Li
Sheng-bin
SB
D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D005006:Ethnicity; D005260:Female; D005828:Genetics, Population; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*; D018609:Tibet