RETRACTED: Selective targeting of checkpoint kinase 1 in tumor cells with a novel potent oncolytic adenovirus.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

This article has been retracted at the request of the editor-in-chief. Similarities were reported between images in this article and an article in Clinical Cancer Research (Zhou et al., 2005, Clin. Cancer Res. 11, 8431-8440, https://10.1158/1078-0432.CCR-05-1085). Q.J., J.Z., X.H., G.C., Y.L., K.L., L.Z., and D.M. were all authors of the Clinical Cancer Research paper as well. These concerns were initially reported in a Pubpeer thread (https://pubpeer.com/publications/FF881782FF5AFD316D42E0C0F00766). Image analysis performed by the editorial office confirmed findings of image recycling in Figures 2A and 3B of the Molecular Therapy article. This reuse (and in part misrepresentation) of data without appropriate attribution represents a severe abuse of the scientific publishing system.
Gao
Qinglei
Q
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Zhou
Jianfeng
J
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Huang
Xiaoyuan
X
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Chen
Gang
G
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Ye
Fei
F
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Lu
Yunping
Y
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Li
Kanyan
K
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Zhuang
Liang
L
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Huang
Mei
M
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Xu
Gang
G
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Wang
Shxuan
S
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China.
Ma
Ding
D
Cancer Biology Research Center, TongJi Hospital, TongJi Medical School, Huazhong University of Science & Technology, WuHan, Hubei 430030, People's Republic of China. Electronic address: dma@tjh.tjmu.edu.cn.
D000256:Adenoviridae / Q000235:genetics* / Q000502:physiology; D017500:Adenovirus E1A Proteins / Q000172:deficiency* / Q000235:genetics; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000201:enzymology / Q000628:therapy* / Q000821:virology; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival; D000071877:Checkpoint Kinase 1; D002945:Cisplatin / Q000627:therapeutic use; D003588:Cytopathogenic Effect, Viral / Q000502:physiology; D016373:DNA, Antisense / Q000235:genetics; D005260:Female; D018390:Gene Targeting; D005822:Genetic Vectors / Q000008:administration & dosage / Q000627:therapeutic use; D006367:HeLa Cells; D006801:Humans; D008113:Liver Neoplasms / Q000201:enzymology / Q000628:therapy* / Q000821:virology; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D008957:Models, Genetic; D011401:Promoter Regions, Genetic; D011494:Protein Kinases / Q000235:genetics* / Q000378:metabolism; D014779:Virus Replication; D023041:Xenograft Model Antitumor Assays
D017500:Adenovirus E1A Proteins; D000970:Antineoplastic Agents; D016373:DNA, Antisense; D011494:Protein Kinases; C000605867:CHEK1 protein, human; D000071877:Checkpoint Kinase 1; C000605869:Chek1 protein, mouse; D002945:Cisplatin