[Reaction of pyridinium salts with active methylene compounds].
The carbon-carbon bond-forming reactions of 1-methyl-2-methylthiophenylpyridinium iodides with active methylene compounds (such as dimethyl malonate, malononitrile) using NaH as a base gave the 2-substituted methylene-1,2-dihydropyridine derivatives.
Fujita
Reiko
R
Tohoku Pharmaceutical University, Sendai City, Japan. refujita@tohoku-pharm.ac.jp
Hoshino
Masato
M
Nishiuchi
Yasuhiro
Y
Tomisawa
Hiroshi
H
D000812:Anhydrides / Q000737:chemistry; D002625:Chemistry, Organic; D008314:Malonates / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D055601:Organic Chemistry Phenomena; D011726:Pyridinium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012964:Sodium / Q000737:chemistry
D000812:Anhydrides; D008314:Malonates; D009570:Nitriles; D011726:Pyridinium Compounds; D012964:Sodium; C000945:dicyanmethane; C005230:methyl malonate