title: Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination.
abstract: Explanted orthopedic implants from 54 patients with aseptic failure and 24 patients with prosthetic knee or hip infection were sonicated in polyethylene bags. The sensitivities of periprosthetic tissue and sonicate fluid cultures for the diagnosis of prosthetic joint infection were 54% and 75%, whereas the specificities were 98% and 87%, respectively. Sonication in bags improved bacterial recovery from the surface of orthopedic implants; however, it lacked specificity, due to bag leakage.
authors.affiliation: Division of Infectious Diseases, Mayo Clinic College of Medicine, 200 First St. S.W., Rochester, MN 55905, USA.
authors.forename: Andrej
authors.initials: A
authors.lastname: Trampuz
authors.forename: Kerryl E
authors.initials: KE
authors.lastname: Piper
authors.forename: Arlen D
authors.initials: AD
authors.lastname: Hanssen
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Osmon
authors.forename: Franklin R
authors.initials: FR
authors.lastname: Cockerill
authors.forename: James M
authors.initials: JM
authors.lastname: Steckelberg
authors.forename: Robin
authors.initials: R
authors.lastname: Patel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D001424:Bacterial Infections / Q000175:diagnosis / Q000382:microbiology; D004866:Equipment Contamination; D005260:Female; D006622:Hip Prosthesis / Q000382:microbiology*; D006801:Humans; D007720:Knee Prosthesis / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000382:microbiology; D012680:Sensitivity and Specificity; D013010:Sonication / Q000009:adverse effects* / Q000295:instrumentation