title: Diversity and utilization of antimalarial ethnophytotherapeutic remedies among the Kikuyus (Central Kenya).
abstract: Plants in Kenya are becoming increasingly important as sources of traditional medicines. The World Health Organization (WHO) has estimated that malaria kills about 2.7 million people every year, 90% of who are from Africa. Malaria continues to be a national concern in Kenya as it plays a major role in the high mortality rates being experienced currently. The use and mis-use of chloroquine to prevent and treat falciparium malaria has led to widespread appearance of chloroquine resistant parasites in Kenya and other tropical countries. These factors and the rising costs of non-chloroquine drugs have made the local people to turn to traditional remedies for management of this menace. This paper examines the current utilization of traditional plant medicines in managing malaria menace in Central Kenya. The results show both indigenous and introduced species are in use indicating traditional medicinal practices in this region are dynamic. In total 58 species in 54 genera and 33 families were identified. The family Rubiaceae was found to have the highest number of reported species. Use of the various taxa is compared between five districts within Central Province of Kenya. The commonest species in this pharmacopoeia are: Caesalpinia volkensii Harms, Strychnos henningsii Gilg, Ajuga remota Benth., Warbugia ugandensis Sprague and Olea europaea L. The first three species are used in all the five districts while the others are restricted in some of the districts. In 74% of the anti-malarial plant species reported in this study, the remedies are obtained in destructive manner and may need conservation measures to ensure sustainable utilization. The results of this study become a basis for selecting plants for further pharmacological and phytochemical studies in developing new and locally relevant anti-malarial agents.
authors.affiliation: Jomo Kenyatta University of Agriculture Science and Technology, Botany Department, P.O. Box 62000, Nairobi, Kenya. gnjerinjoroge@hotmail.com
authors.forename: Grace N
authors.initials: GN
authors.lastname: Njoroge
authors.forename: Rainer W
authors.initials: RW
authors.lastname: Bussmann
mesh_terms: D000962:Antimalarials / Q000627:therapeutic use*; D019448:Ethnobotany; D005260:Female; D006801:Humans; D007630:Kenya; D008288:Malaria / Q000517:prevention & control*; D008297:Male; D016488:Medicine, African Traditional; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use*; D018514:Plant Structures; D010946:Plants, Medicinal
chemical_list: D000962:Antimalarials; D028321:Plant Preparations