title: [The extracellular matrix in bone tissue engineering].
abstract: OBJECTIVE
  To review the research progress of osteoblast extracellular matrix (ECM) and its application in bone tissue engineering.
  
  
  METHODS
  The recent related literatures were extensively reviewed.
  
  
  RESULTS
  The ECM was complex in its components. The configuration of cell and cell's adhesion, migration, proliferation, and differentiation were subject to the ECM. The bioactivity of the tissue engineering products was revealed by ECM, which predicted the product's efficiency in clinic application.
  
  
  CONCLUSIONS
  ECM has the potential to become the effective index in evaluating tissue engineered products.
authors.affiliation: Division of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy, Sichuan University, Chengdu Sichuan 610041, PR China.
authors.forename: Jie
authors.initials: J
authors.lastname: Qi
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Yang
mesh_terms: D005109:Extracellular Matrix; D010006:Osteoblasts / Q000166:cytology*; D023822:Tissue Engineering