title: [Inter-laboratory validation studies of biological method for determination of streptomycin in royal jelly].
abstract: Inter-laboratory validation studies were conducted in 6 laboratories to validate the biological method for determination of streptomycin in royal jelly. Streptomycin spiked at the level of 0.2 and 1.0 ppm was analyzed. Mean recoveries were 89 and 96%, reproducibility relative standard deviations (RSD(R)) were 15.0 and 14.0%, HORRAT(R) values were 0.7 and 0.9. Samples containing residues at the levels of 0.25 and 0.80 ppm were analyzed. Mean recoveries were 113 and 99%, RSD(R) were 15.0 and 10.4%, and HORRAT(R) values were 0.8 and 0.6. The determination limit was 0.1 ppm. These results show that this method has good performance.
authors.affiliation: Japan Food Research Laboratories Nagoya Branch, 4-5-13, Osu, Naka-ku, Nagoya 460-0011, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Fujita
authors.forename: Keiko
authors.initials: K
authors.lastname: Akita
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yoneyama
authors.forename: Kiyoki
authors.initials: K
authors.lastname: Sengoku
authors.forename: Yoshimichi
authors.initials: Y
authors.lastname: Sumiya
authors.forename: Megumi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Yuri
authors.initials: Y
authors.lastname: Mizutani
authors.forename: Hizuru
authors.initials: H
authors.lastname: Ohdaira
authors.forename: Tsuguo
authors.initials: T
authors.lastname: Hirose
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D001681:Biological Assay / Q000379:methods*; D004350:Drug Residues / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D007753:Laboratories; D013307:Streptomycin / Q000032:analysis*; D000099219:Royal Jelly
chemical_list: D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D013307:Streptomycin; D000099219:Royal Jelly