[HLA-DRB1 polymorphism in the Ewenki Ethnic of Inner Mongolian].
OBJECTIVE
To study the HLA-DRB1 genetic polymorphism in the Ewenki of Inner mongolia.


METHODS
HLA-DRB1 allele polymorphisms in 84 normal Ewenki were determined by PCR with sequencing based typing (SBT).


RESULTS
Twenty-five HLA-DRB1 alleles were observed. The allele frequency of HLA-DRB1*03011(14.88%) is the highest; the allele frequencies of HLA -DRB1*09012 (13.69%), DRB1*07011(8.92%), DRB1*04011(9.52%) and DRB1*12011(8.33%) are lower.


CONCLUSIONS
The distribution of HLA-DRB1 alleles frequencies in normal Ewenki from Inner Mongolia exhibits a unique profile, which is of important reference value for studies on anthropology and related illnesses in Ewenki population.
Hai
Rong
R
Clinical Medical Research Center, Inner Mongolian Medical College, Huhehhte, Inner Mongolian 010050, P.R. China.
Bi
Li-fu
LF
Su
Xiu-lan
XL
D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005006:Ethnicity; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D011110:Polymorphism, Genetic
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C553509:HLA-DRB1*09:01:02 antigen