[Insulin delivery by using PLGA nanoparticulate system].
The usefulness of PLGA nanoparticulate system for insulin delivery is described. The preparation methods of PLGA nanosphere encapsulating insulin are reviewed. To improve the therapeutic effect of insulin, the method of drug releasing control of PLGA nanosphere is discussed. The practical insulin DDS of PLGA nanosphere is summerized.
Kawashima
Yoshiaki
Y
School of Pharmaceutical Science, Aichi Gakuin University.
D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy; D004337:Drug Carriers; D007328:Insulin / Q000008:administration & dosage*; D019344:Lactic Acid; D049329:Nanostructures; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers; D051381:Rats
D004337:Drug Carriers; D007328:Insulin; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid