Serum leptin levels in patients with allergic rhinitis.
OBJECTIVE
To investigate the serum leptin levels in patients with allergic rhinitis during the symptomatic period.


METHODS
A randomized, prospective study was performed on 26 adult patients with allergic rhinitis and 20 control subjects with similar age, sex and body mass index in a tertiary otolaryngology center.


RESULTS
Leptin levels were 28.8 +/- 14.1 ng/mL in the patients with allergic rhinitis, and 20.8 +/- 13.5 ng/mL in the control group respectively. The difference between the groups was statistically significant (p = 0.04).


CONCLUSIONS
Serum leptin levels were found to be significantly higher in patients with allergic rhinitis in symptomatic period.


CONCLUSIONS
Apart from its primary role in the regulation of body weight and energy expenditure, leptin may have a role in the inflammatory process of the allergic rhinitis.
Unal
Murat
M
Department of Biochemistry, Mersin University, School of Medicine, Mersin, Turkey. munal@mersin.edu.tr
Eskandari
Gülçin
G
Muşlu
Necati
N
Pata
Yavuz Selim
YS
Akbaş
Yücel
Y
D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007249:Inflammation / Q000276:immunology; D020738:Leptin / Q000097:blood*; D008297:Male; D011446:Prospective Studies; D012220:Rhinitis / Q000097:blood* / Q000276:immunology
D020738:Leptin