[Evaluation of the antimicrobial potential of immune sera].
The inhibiting activity of blood sera obtained from 20 volunteers immunized with the multi-component vaccine "PYOPOL", 25 nonimmune donors and 7 lots of human antistaphylococcal immunoglobulin with respect to Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa has been studied in the liquid nutrient medium with the use an automated microbiological analyzer. The sera of donors immunized with the vaccine "PYOPOL" have been found to possess high antimicrobial activity, comparable with the definite concentration of the antiseptic agent "Myramistin". The proposed method may be recommended for the evaluation of the bacteriostatic activity of different immuno- biological preparations.
Mikhaĭlova
N A
NA
Bitkova
E E
EE
Skala
L Z
LZ
Khvatov
V B
VB
Krivoshein
Iu S
IuS
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001428:Bacterial Vaccines / Q000276:immunology; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000254:growth & development; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology*; D008297:Male; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development; D014611:Vaccination; D017778:Vaccines, Combined / Q000276:immunology
D000900:Anti-Bacterial Agents; D001428:Bacterial Vaccines; D007106:Immune Sera; D017778:Vaccines, Combined