title: [Extranodal T/NK-cell lymphoma, nasal type: a case report and review of the literature].
abstract: Extranodal T/NK-cell lymphoma, nasal type: a case report and review of the literature. Extranodal NK/T-cell lymphoma, nasal type, is an extranodal lymphoma, usually with an NK-cell phenotype and EBV positive, with a broad morphologic spectrum, frequent necrosis and angioinvasion, and most commonly presenting in the midfacial region, but also in other extranodal sites. We present the case of a 42-years old-man with a intranasal mass, left cervical adenopathies and indolent thrombocytosis. The biopsy of the nasal mass showed a diffuse infiltrate of medium-sized lymphoid cells, with slightly irregular nuclei and moderate polymorphous. The immunophenotype of tumor cells was CD45+, cCD3+, Granzyme B+, CD56+, CD20-,CD4-,CD8-, LMP1(EBV)-. The diagnosis of the case was Extranodal T/NK-cell lymphoma, nasal type. There was not disseminated disease in the extent studies. With the diagnosis of localized extranodal T/NK-cell lymphoma and reactive thrombocytosis, the patient was treated with chemotherapy and sequential radiotherapy, followed by bone marrow transplantation.
authors.affiliation: Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid. drkhosravi@hotmail.com
authors.forename: P
authors.initials: P
authors.lastname: Khosravi Shahi
authors.forename: V M
authors.initials: VM
authors.lastname: Díaz Muñoz de la Espada
mesh_terms: D000328:Adult; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural; D016399:Lymphoma, T-Cell / Q000276:immunology / Q000473:pathology*; D008297:Male; D009669:Nose Neoplasms / Q000276:immunology / Q000473:pathology*