title: Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide.
abstract: Staphylococcus aureus responds with protective strategies against phagocyte-derived reactive oxidants to infect humans. Herein, we report the transcriptome analysis of the cellular response of S. aureus to hydrogen peroxide-induced oxidative stress. The data indicate that the oxidative response includes the induction of genes involved in virulence, DNA repair, and notably, anaerobic metabolism.
authors.affiliation: Center for Biosystems Research, University of Maryland Biotechnology Institute, College Park 20742, USA.
authors.forename: Wook
authors.initials: W
authors.lastname: Chang
authors.forename: David A
authors.initials: DA
authors.lastname: Small
authors.forename: Freshteh
authors.initials: F
authors.lastname: Toghrol
authors.forename: William E
authors.initials: WE
authors.lastname: Bentley
mesh_terms: D020869:Gene Expression Profiling; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D006861:Hydrogen Peroxide; D020411:Oligonucleotide Array Sequence Analysis; D016133:Polymerase Chain Reaction; D012329:RNA, Bacterial / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D013211:Staphylococcus aureus / Q000235:genetics* / Q000502:physiology; D013997:Time Factors; D014158:Transcription, Genetic
chemical_list: D012329:RNA, Bacterial; D012333:RNA, Messenger; D006861:Hydrogen Peroxide