title: [Pre-clinical and clinical studies on bone morphogenetic proteins for regenerative therapies in dentistry field].
abstract: Many researches were done on the application of bone morphogenetic proteins (BMPs) for periodontal regeneration, and bone regeneration followed by the insertion of dental implants. There are many reports which suggested that BMPs enhanced alveolar bone and cementum formations in the pre-clinical studies on periodontal regeneration. However, it is suggested that ankylosis might disturb the ideal periodontal regeneration. There are also many reports which suggested that BMPs were effective for alveolar ridge augmentation for the insertion of dental implant in pre-clinical and clinical studies. There are great hopes that the application of BMPs for the regenerative therapies on diseases involving bone loss.
authors.affiliation: Department of Oral Health Care Promotion, School of Oral Health Care Sciences, Faculty of Dentistry, Tokyo Medical and Dental University.
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Kinoshita
mesh_terms: D000539:Alveolar Process / Q000254:growth & development; D000818:Animals; D001846:Bone Development / Q000187:drug effects*; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use*; D001861:Bone Regeneration / Q000187:drug effects*; D003739:Dental Cementum / Q000187:drug effects; D015921:Dental Implants; D004285:Dogs; D006801:Humans; D051381:Rats
chemical_list: D019485:Bone Morphogenetic Proteins; D015921:Dental Implants