title: Effects of fermented soy milk on the liver lipids under oxidative stress.
abstract: OBJECTIVE
  To investigate the effects of fermented soy milk powder on the antioxidative status and lipid metabolism in the livers of CCl4-injected rats.
  
  
  METHODS
  Forty-five healthy male Sprague-Dawley rats were randomly assigned to five groups according to five different diets: control (AIN-76), AIN-76+high-dose fermented soy milk powder, AIN-76+low-dose fermented soy milk powder, AIN-76+high-dose milk yogurt powder and AIN-76+low-dose milk yogurt powder. The experiment lasted for 8 wk. After 4 wk, all the rats received intraperitoneal administration of CCl(4)(0.2 mL/100 g body weight) every week. Total cholesterol (TC), triglyceride (TG), TBARS, ALP, and antioxidative enzymes in the liver were evaluated.
  
  
  RESULTS
  There was also no significant difference in TBARS and antioxidative enzymes in the liver. TC and TG in the groups fed with fermented soy milk powder were generally lower than those fed with casein powder.
  
  
  CONCLUSIONS
  Consumption of fermented soy milk was positive in lowering total cholesterol and TG accumulation in the liver under CCl(4)-induced oxidative stress.
authors.affiliation: Graduate Institute of Nutrition and Health Sciences, Taipei Medical University, (110) 250 Wu-Hsing Street, Taipei, Taiwan, China. lin5611@tmu.edu.tw
authors.forename: Ching-Yi
authors.initials: CY
authors.lastname: Lin
authors.forename: Zheng-Yu
authors.initials: ZY
authors.lastname: Tsai
authors.forename: I-Chi
authors.initials: IC
authors.lastname: Cheng
authors.forename: Shyh-Hsiang
authors.initials: SH
authors.lastname: Lin
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001628:Beverages; D002251:Carbon Tetrachloride / Q000633:toxicity; D005285:Fermentation; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D011208:Powders; D051381:Rats; D017207:Rats, Sprague-Dawley; D013025:Glycine max; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D000975:Antioxidants; D011208:Powders; D017392:Thiobarbituric Acid Reactive Substances; D002251:Carbon Tetrachloride; D000469:Alkaline Phosphatase