Chronic urticaria and thyroid auto-immunity.
The association between thyroid auto-immunity and chronic urticaria (CU) has long been recognized as significant. The prevalence of antithyroid antibodies (ATAs) has been estimated as 12 to 29%. However, most studies have suggested that these auto-antibodies are not a direct causative agent in CU. In some patients, ATAs are associated with the presence of anti-immunoglobulin E receptor antibodies. It appears more likely that these antibodies are associated, parallel, auto-immune events. The effects of hormonal treatment on clinical symptoms of CU are controversial. They must be evaluated by controlled trials.
Doutre
Marie-Sylvie
MS
Department of Dermatology, Université Victor-Segalen, Hôpital Haut-Lévêque, Pessac, France. marie-sylvie.doutre@chu-bordeaux.fr
D001323:Autoantibodies / Q000097:blood; D015551:Autoimmunity; D002908:Chronic Disease; D006801:Humans; D007453:Iodide Peroxidase / Q000276:immunology; D013959:Thyroid Diseases / Q000150:complications / Q000188:drug therapy; D013961:Thyroid Gland / Q000276:immunology*; D014581:Urticaria / Q000209:etiology* / Q000276:immunology
D001323:Autoantibodies; C006606:anti-thyroglobulin; D007453:Iodide Peroxidase