Oxidation of alcohols to carbonyl compounds with CrO3.SiO2 in supercritical carbon dioxide.
Supercritical carbon dioxide (scCO2) is an effective reaction medium to perform the oxidation of primary and secondary aliphatic alcohols to the corresponding carbonyl compounds with chromium trioxide supported on silica. These reactions were performed by flowing a solution of the alcohol in scCO2 through a column containing the supported reagent and recovering the product by depressurization. This method avoids the use of organic solvents and the contamination of the products with chromium species.
González-Núñez
María Elena
ME
Departamento de Química Orgánica, Universidad de Valencia, Avda. V. Andrés Estellés s/n, 46100-Burjassot (Valencia), Spain.
Mello
Rossella
R
Olmos
Andrea
A
Acerete
Rafael
R
Asensio
Gregorio
G