Other than potency, are all statins the same?
Statins have been shown to interact with metabolic pathways that potentially affect physiologic functions beyond cholesterol balance. We may broadly categorize non-lipid effects of statins as clinically favorable or clinically detrimental. Whether non-lipid effects of statins are of clinical significance and whether there are differences in non-lipid effects among statins remain points of major current controversy. This review evaluates the available information on potential differences among statins in non-lipid effects.
Abate
Nicola
N
Department of Internal Medicine, UT Southwestern Medical Center, 6011 Harry Hines Boulevard, Dallas, TX 75390-9169, USA. Nicola.abate@utsouthwestern.edu
Chandalia
Manisha
M
D002986:Clinical Trials as Topic; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000494:pharmacology*; D006949:Hyperlipidemias / Q000188:drug therapy*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors