title: Basaloid squamous cell carcinoma of the larynx: a case report.
abstract: Basaloid squamous cell carcinoma (SCC) is a very rare, high grade, and aggressive variant of SCC, with a predilection for the upper aerodigestive system. Treatment should include surgery of the primary tumor and dissection of the cervical lymph nodes, followed by radiotherapy. We present a 50-year-old man with basaloid SCC of the supraglottic larynx, which was initially misdiagnosed as SCC. Supraglottic laryngectomy with bilateral radical neck dissection was performed, and radiotherapy was applied postoperatively. During a follow-up of 26 months, no evidence for recurrence was found. Basaloid SCC should be considered in the differential diagnosis of upper aerodigestive system malignancies because it has a distinct prognostic significance compared to conventional SCC.
authors.affiliation: Department of Otolaryngology, Medicine Faculty of Marmara University, Istanbul, Turkey. ozturkmarmara@hotmail.com
authors.forename: Ozmen
authors.initials: O
authors.lastname: Oztürk
authors.forename: Murat
authors.initials: M
authors.lastname: Sari
authors.forename: Selçuk
authors.initials: S
authors.lastname: Inanli
authors.forename: Esin Kotiloğlu
authors.initials: EK
authors.lastname: Kara
mesh_terms: D002281:Carcinoma, Basosquamous / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D008297:Male; D008875:Middle Aged