Maturation of auditory steady-state responses in normal babies.
OBJECTIVE
To track the development of the auditory steady-state response (ASSR) through the neonatal and early infant periods in a group of normal-hearing babies.


METHODS
This longitudinal study involved assessment at four data collection points. ASSR thresholds to modulated 500 Hz and 4 kHz tones were established in 20 full-term subjects at 0, 2, 4, and 6 wks of age.


RESULTS
Significant developmental changes were observed for both test frequencies. Mean ASSR threshold levels decreased by approximately 10 dB between the week 0 and week 6 data collection points.


CONCLUSIONS
The results of this study indicate that ASSR threshold levels in normal-hearing neonates and young infants are different from those observed in older subjects. Clinical application of the ASSR procedure in this population will need to take into account developmental changes occurring in the first weeks of life. Furthermore, the findings indicate that ASSR thresholds in normal-hearing babies at 6 wks of age are not yet mature.
Rance
Gary
G
University of Melbourne, Melbourne, Australia. grance@unimelb.edua.au
Tomlin
Dani
D
D000367:Age Factors; D001306:Auditory Pathways / Q000502:physiology*; D001309:Auditory Threshold; D002657:Child Development / Q000502:physiology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000254:growth & development / Q000502:physiology*; D008137:Longitudinal Studies; D008297:Male