Synthesis of 3,6-diaminophthalimides for ureidophthalimide-based foldamers.
[reaction: see text]. Herein, we report an improved methodology for the synthesis of a variety of 3,6-diaminophthalimides in high yields. This enables decoration of the periphery of foldamers with a wide range of functionalities.
Sinkeldam
Renatus W
RW
Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
van Houtem
Michel H C J
MH
Koeckelberghs
Guy
G
Vekemans
Jef A J M
JA
Meijer
E W
EW