[The practice guideline 'Carcinoma of the oral cavity and oropharynx'].
With a total incidence of ca. 800 per year, oral cavity or oropharyngeal carcinoma represents only a small fraction of the total number of cases of cancer in The Netherlands. In order to achieve as much nationwide uniformity as possible in its diagnosis, treatment, after-care and follow-up, a practice guideline has now been developed. The diagnosis of the primary tumour and the neck, careful clinical examination is complemented by echography, often combined with a biopsy, MRI and CT, while technetium scintigraphy in combination with an orthopantomogram is used to detect invasion of the mandible. The smaller oropharyngeal carcinomas (T1 and T2), surgery and radiotherapy (external therapy or brachytherapy) are equally useful, but for the larger carcinomas (T3 and T4) in patients in good general condition, surgery in combination with radiotherapy is preferred. When radiotherapy is chosen, then brachytherapy is preferred for the smaller tumours of the tongue and the floor of the mouth. In patients without demonstrable metastases to the lymph nodes, just as in the case oforopharyngeal carcinomas, the decision whether or not to treat the neck depends on the chances that cervical lymph node metastases are present: when the risk is smaller than 20% (as with smaller tumours), then a wait-and-see policy is justified, but if the risk is greater than 20% (as with larger tumours or very thick rumours), then the neck should be treated, either surgically or by radiotherapy. The practice guideline also contains information regarding decision making, information and communication, palliative therapy and symptomatic treatment, psychosocial assistance, prosthetic reconstruction, physiotherapy, oral hygiene, nutrition and dietetics, swallowing and speech rehabilitation, and the policy with regard to smoking and alcohol consumption.
Knegt
P P
PP
Erasmus MC, Postbus 2040, 3000 CA Rotterdam. p.knegt@erasmusmc.nl
Keus
R B
RB
Roodenburg
J L N
JL
D001918:Brachytherapy; D002277:Carcinoma / Q000175:diagnosis* / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008207:Lymphatic Metastasis; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000628:therapy; D009367:Neoplasm Staging; D009426:Netherlands; D009959:Oropharyngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D010166:Palliative Care; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011882:Radiotherapy, High-Energy; D012955:Societies, Medical