title: Rupture of adductor longus tendon due to ciprofloxacin.
abstract: We present a rare case of spontaneous rupture of the adductor longus tendon induced by ciprofloxacin. A 35-year-old man was diagnosed with pneumonia and was recommended ciprofloxacin 500 mg iv twice a day for 7 days. Three days after receiving the initial dose, he developed discomfort in his left medial thigh, and pain and swelling in the same area followed ten days later. He consulted us when he noted a palpable mass on the medial side of his left thigh, and MRI study revealed adductor longus tendon rupture. There was no obvious underlying disease or other factor causing fragility of his adductor longus tendon. We review the pathophysiological mechanisms leading to fluoroquinolone-related tendon rupture as well as the risk factors and discuss proper management.
authors.affiliation: Sparta Hospital, Sparta and Laiko Hospital, Athens, Greece. gmouzopoulos@yahoo.gr
authors.forename: George
authors.initials: G
authors.lastname: Mouzopoulos
authors.forename: Mihalis
authors.initials: M
authors.lastname: Stamatakos
authors.forename: George
authors.initials: G
authors.lastname: Vasiliadis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Skandalakis
mesh_terms: D000328:Adult; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy*; D018570:Risk Assessment; D012422:Rupture, Spontaneous / Q000139:chemically induced / Q000473:pathology; D013708:Tendon Injuries / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D002939:Ciprofloxacin