title: Preservation of ventricular function in amateur athletes after completion of a marathon.
abstract: BACKGROUND
  Previous studies have demonstrated the development of impaired systolic function and new segmental wall motion abnormalities following completion of ultraendurance events. Limited information is available on the effect of an endurance event such as a marathon on the left ventricular indices and hemodynamics.
  
  
  METHODS
  We examined 45 patients (26 men, 19 women with the average age of 35+/- 8 years) who successfully trained and completed the 2001 Chicago Marathon (26.2 miles). Transthoracic 2-dimensional and Doppler echocardiography (TTE) was preformed prior to the marathon (17+/-10.7 days), immediately following the marathon (71+/-42 minutes), and at follow-up (29+/-12.9 days).
  
  
  RESULTS
  Left ventricular end diastolic volumes declined immediately post marathon and returned to baseline at the one-month follow-up. Ejection fraction was maintained and no regional wall motion abnormalities were identified at any time point. Diastolic parameters decreased immediately post marathon but returned to baseline during follow-up principally reflecting a change in volume status.
  
  
  CONCLUSIONS
  Marathon running by a group of well-trained recreational athletes does not result in impairment of left ventricular systolic or diastolic function.
authors.affiliation: Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
authors.forename: Allison J
authors.initials: AJ
authors.lastname: Kean
authors.forename: Veronica R
authors.initials: VR
authors.lastname: McCloskey
authors.forename: Frank F
authors.initials: FF
authors.lastname: Seghatol
authors.forename: Greg D
authors.initials: GD
authors.lastname: Ewert
authors.forename: David J
authors.initials: DJ
authors.lastname: Mehlman
authors.forename: David D
authors.initials: DD
authors.lastname: McPherson
authors.forename: Vera H
authors.initials: VH
authors.lastname: Rigolin
mesh_terms: D000328:Adult; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010807:Physical Endurance / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology; D012420:Running / Q000502:physiology*; D013318:Stroke Volume / Q000502:physiology; D016276:Ventricular Function; D016277:Ventricular Function, Left / Q000502:physiology*