title: [Ratio of lymph node metastasis in gastric carcinoma after D2 gastrectomy].
abstract: The classification of lymph node metastasis in patients with gastric carcinoma is controversial. In the past, all systems used for this disease defined N classification by the location of lymph node metastases relatively to the primary tumor. In the 1997, the UICC and AJCC redefined the pathologic nodal status on the basis of the number of involved nodes rather than their location. More recently, the ratio between the number of metastatic and the total examined lymph nodes has been proposed as a new quantitative staging system. Aim of our study was to clarify the outcome of the ratio of the metastatic lymph nodes (RML) in a monoinstitutional series of 164 patient with primary gastric cancer who underwent gastrectomy with D2 lymph node dissection. Our data showed that ratio of metastatic lymph nodes is a simple, convenient, and reproducible staging system with an ability to predict surgical results and it is an independent prognostic factor after D2-gastrectomy.
authors.affiliation: Dipartimento di Scienze Chirurgiche, Istituto di Patologia Speciale Chirurgica. Università Cattolica del Sacro Cuore, Roma.
authors.forename: R
authors.initials: R
authors.lastname: Persiani
authors.forename: S
authors.initials: S
authors.lastname: Rausei
authors.forename: A
authors.initials: A
authors.lastname: Biondi
authors.forename: V
authors.initials: V
authors.lastname: Vigorita
authors.forename: G
authors.initials: G
authors.lastname: Retrosi
authors.forename: D
authors.initials: D
authors.lastname: D'Ugo
mesh_terms: D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008207:Lymphatic Metastasis; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*