[Hope to the cancer therapy: cancer stem cell].
Cancer stem cells are defined as rare cells in cancer tissues with indefinite potential for self-renewal that drives tumorigenesis. It was first extensively documented for leukaemia and multiple myeloma. It has also been found in solid cancers such as human breast cancer and nervous system tumors. Studies of cancer stem cell biology and mechanisms of tumorigenesis are lending insight into the origins of cancer and will ultimately yield new approaches to fight cancer.
Liu
Da-qing
DQ
Department of Stem Cell and Regenerative Medicine, Institute of Blood Transfusion, Academy of Military Medical Science, Beijing 100850, China.
Pei
Xue-tao
XT
D000818:Animals; D002471:Cell Transformation, Neoplastic; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000473:pathology / Q000628:therapy; D014411:Neoplastic Stem Cells / Q000166:cytology*; D014410:Tumor Stem Cell Assay / Q000379:methods