title: Sertoli-Leydig cell tumour in a postmenopausal woman showing all facets of the insulin resistance syndrome (IRS).
abstract: Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of < 0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels due to a Sertoli-Leydig cell tumour. This is the first case to suggest an association between IRS and Sertoli-Leydig cell tumours. Furthermore, we highlight the difficulties in detecting this ovarian tumour with sonography.
authors.affiliation: Department of Obstetrics and Gynecology, the Sahlgrenska Academy at Göteborg University, Sweden. eva.dahlgren@vgregion.se
authors.forename: Eva
authors.initials: E
authors.lastname: Dahlgren
authors.forename: Berit
authors.initials: B
authors.lastname: Gull
authors.forename: Roger
authors.initials: R
authors.lastname: Willén
authors.forename: Frank
authors.initials: F
authors.lastname: Sundler
authors.forename: Thord
authors.initials: T
authors.lastname: Rosén
authors.forename: Per-Anders
authors.initials: PA
authors.lastname: Jansson
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007333:Insulin Resistance; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology*; D018310:Sertoli-Leydig Cell Tumor / Q000150:complications* / Q000473:pathology*