Two new sesquiterpene polyesters from the seeds of Euonymus nanoides LOES.
Two new beta-dihydroagarofuran sesquiterpene polyesters, 1S,13-diacetyloxy-4S-hydroxy-6R-(3-)furancarbonyloxy-9S-cinnamoyloxy-beta-dihydroagarofuran (1) and 1S,6R-di(2-)methylbutanoyloxy-4S-hydroxy-8S-benzoyloxy-9R-(3-)furancarbonyloxy-13-acetyloxy-beta-dihydroagarofuran (2), together with one known compound (3) were isolated from the seeds of Euonymus nanoides LOES. Their structures were elucidated by spectroscopic data interpretation. Compound 2 showed moderate antitumor activity against BEL-7402, P-388, HL-60 and A-549.
Wang
Hong
H
College of Pharmaceutical Science, Zhejiang University of Technology, Hangshou, PR China. hongw@zjut.edu.cn
Tian
Xuan
X
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002853:Chromatography, Liquid; D002855:Chromatography, Thin Layer; D004354:Drug Screening Assays, Antitumor; D029756:Euonymus / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D012639:Seeds; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D000972:Antineoplastic Agents, Phytogenic; D012717:Sesquiterpenes