[Osteoporosis treatment].
As for any chronic disease, adherence to osteoporosis treatment is low. Folates and vitamin B12 decrease hip fracture risk in elderly Japanese with stroke. Raloxifene (Evista) decreases the incidence of positive estrogen receptor breast cancer and could prevent cardiovascular events in patients at high risk. Strontium ranelate (Protélos) prevents hip fracture in elderly women. The action of alendronate (Fosamax) on bone mineral density and markers of bone remodelling is of higher amplitude than that of risedronate (Actonel). Once monthly ibandronate (Bonviva) increases bone mineral density in post menopausal women with osteoporosis. Excessive suppression of bone remodelling and osteonecrosis of the yaws could be related to bisphosphonate intake.
Uebelhart
B
B
Service des maladies osseuses, Centre collaborateur de I'OMS pour la prevention de l'ostéoporose, Departement de rehabilitation et gériatrie, HUG, 1211 Geneve 14. Brigitte.Uebelhart@hcuge.ch
Rizzoli
R
R
D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D001862:Bone Resorption; D002908:Chronic Disease; D005492:Folic Acid / Q000627:therapeutic use; D050723:Fractures, Bone / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D010020:Osteonecrosis / Q000209:etiology / Q000517:prevention & control; D010024:Osteoporosis / Q000150:complications* / Q000188:drug therapy*; D014805:Vitamin B 12 / Q000627:therapeutic use
D050071:Bone Density Conservation Agents; D005492:Folic Acid; D014805:Vitamin B 12