Palladium-catalyzed arylation and heteroarylation of azolopyrimidines.
A comparative study of the palladium-catalyzed arylation and heteroarylation of 5-bromoazolopyrimidines shows that aryl and electron-rich heteroaryl boronic acids gave higher yields than those obtained using the corresponding aryl and heteroaryl tributyl stannanes. In contrast, the reaction with electron-poor heteroaryl tributyl stannanes gave better results than the corresponding boronic acids.
Mendiola
Javier
J
Departamento de Química Orgánica, Universidad de Alcalá, 28871-Alcalá de Henares, Madrid, Spain.
Castellote
Isabel
I
Alvarez-Builla
Julio
J
Fernández-Gadea
Javier
J
Gómez
Antonio
A
Vaquero
Juan J
JJ
D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
D001391:Azo Compounds; D001897:Boronic Acids; D011743:Pyrimidines; D010165:Palladium; C030986:pyrimidine