Self-adhesion among phospholipid vesicles.
A compound was synthesized that binds to a phospholipid bilayer via a hydrophobic steroid thereby projecting a strong multi-hydrogen bonding unit into the surrounding water. As shown by light scattering, light microscopy, and cryo-HRSEM, this latter unit self-adheres and induces membrane-membrane attachments, as found in many biological systems.
Menger
F M
FM
Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA. menger@emory.edu
Zhang
Hailing
H
D002448:Cell Adhesion; D019281:Dimerization; D006860:Hydrogen Bonding; D008051:Lipid Bilayers / Q000737:chemistry* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000737:chemistry* / Q000378:metabolism; D011744:Pyrimidinones / Q000737:chemistry
C029046:2-ureido-4(3H)-pyrimidinone; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D011744:Pyrimidinones; C028694:1-palmitoyl-2-oleoylphosphatidylcholine