Optical coherent tomography features of malattia leventinese.
OBJECTIVE
Malattia leventinese (ML) is an inherited macular degeneration characterized by the presence of large paracentral and small radial drusen. Our purpose was to describe optical coherent tomography (OCT) features observed in ML.


METHODS
Prospective observational case series.


METHODS
Ten eyes from five patients with ML aged 27 to 44 years were prospectively included. Best-corrected visual acuity, fundus color photography of the retina, and OCT were performed in each patient.


RESULTS
OCT revealed a hyperreflective thickening of the retinal pigment epithelium-Bruch membrane complex, associated with localized dome-shaped elevations. Retinal thickness above the drusen ranged from 221 to 292 microm (mean 260 microm). Foveal thickness ranged from 72 to 200 microm (mean 144 microm)


CONCLUSIONS
The large paracentral drusen presented either as a thickening of the retinal pigment epithelium-Bruch complex or as local limited elevation of retinal pigment epithelium-Bruch complex, both associated with preservation of the neurosensory retina.
Souied
Eric H
EH
Clinique Ophthamologique Universitaire de Créteil, Höpital Intercommunal, Créteil, France. eric.souied@chicreteil.fr
Leveziel
Nicolas
N
Letien
Valerie
V
Darmon
Jacques
J
Coscas
Gabriel
G
Soubrane
Gisele
G
D000328:Adult; D016570:Bruch Membrane / Q000473:pathology*; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis* / Q000235:genetics*; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D011446:Prospective Studies; D015593:Retinal Drusen / Q000175:diagnosis*; D041623:Tomography, Optical Coherence