title: [Selected issues of pathogenesis and clinical symptomatology of chronic venous insufficiency].
abstract: The paper presents a brief review of existing theories concerning development and progression of trophic disturbances in chronic venous insufficiency (CVI). The interrelation of physiopathological processes during CVI at the level of micro- and macrocirculation is delineated, the necessity and feasibility of medical therapy with the last generation pharmacological agents is stressed.
authors.forename: S V
authors.initials: SV
authors.lastname: Sapelkin
mesh_terms: D002908:Chronic Disease; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008833:Microcirculation / Q000502:physiology; D012307:Risk Factors; D014689:Venous Insufficiency / Q000209:etiology / Q000503:physiopathology