Total synthesis of (+)-lasonolide A.
[structure: see text]. An enantiocontrolled total synthesis of (+)-lasonolide A has been accomplished by using the sequential cross metathesis and macrolactonization for the key assembly of the 20-membered polyene macrolide core of the natural product.
Yoshimura
Tomoyuki
T
Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78 Sho-machi, Tokushima 770-8505, Japan.
Yakushiji
Fumika
F
Kondo
Shingo
S
Wu
Xiaofeng
X
Shindo
Mitsuru
M
Shishido
Kozo
K
D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D001688:Biological Products; D018942:Macrolides; C450700:lasonolide A