title: In117, an unusual In0-like class 1 integron containing CR1 and bla(CTX-M-2) and associated with a Tn21-like element.
abstract: An unusual In0-like class 1 integron containing a common region that includes the putative recombinase gene named orf513 (CR1) and bla(CTX-M-2) was characterized from Escherichia coli. The integron contained an unusual gene cassette array, estX-aadA1, embedded between the 5'-conserved segment (5'-CS) and 3'-CS1 regions and was flanked by mer-Tn21 sequences downstream of the tni truncated module. This element constitutes one of the few examples of CR1-bearing class 1 integrons that has been fully characterized.
authors.affiliation: Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain.
authors.forename: Aránzazu
authors.initials: A
authors.lastname: Valverde
authors.forename: Rafael
authors.initials: R
authors.lastname: Cantón
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Galán
authors.forename: Patrice
authors.initials: P
authors.lastname: Nordmann
authors.forename: Fernando
authors.initials: F
authors.lastname: Baquero
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Coque
mesh_terms: D001483:Base Sequence; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D032023:Integrons; D008969:Molecular Sequence Data; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; C071167:beta-lactamase CTX-2; D001618:beta-Lactamases