title: Strategies for developing therapeutic application of human embryonic stem cells.
abstract: The ongoing debate on human embryonic stem cells (hESC) is fueled by ethical concerns but also by the legitimate hope that hESC could one day be used for the cure of presently untreatable human diseases. Here we discuss current approaches to and constraints upon hESC differentiation and describe their potential application in clinical medicine.
authors.affiliation: Department of Internal Medicine and Veterans Affairs Medical Center, Iowa City, Iowa, USA.
authors.forename: Sudhanshu P
authors.initials: SP
authors.lastname: Raikwar
authors.forename: Thomas
authors.initials: T
authors.lastname: Mueller
authors.forename: Nicholas
authors.initials: N
authors.lastname: Zavazava
mesh_terms: D002454:Cell Differentiation; D002478:Cells, Cultured; D033041:Embryo Research; D006801:Humans; D010641:Phenotype; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology