title: Dermatomyositis complicated with Kaposi sarcoma: a case report.
abstract: We describe the case of a 75-year-old Italian woman affected by dermatomyositis (DM) treated with steroid, high-dose intravenous immunoglobulins (IVIgs) and cyclophosphamide (CPX), taken orally. After a few months, the patient presented multiple red vascular skin lesions diagnosed as Kaposi sarcoma (KS). Steroid was furtherly reduced, and CPX was stopped. We put the patient on chemotherapy with intravenous infusion of vinblastine and vincristine on alternate weeks obtaining the remission of KS. DM is well controlled by a low-dosage steroid and high-dose IVIgs.
authors.affiliation: Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Policlinico GB Rossi, P. le LA Scuro, 37134 Verona, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Simeoni
authors.forename: Antonio
authors.initials: A
authors.lastname: Puccetti
authors.forename: Sara
authors.initials: S
authors.lastname: Moruzzi
authors.forename: Elisa
authors.initials: E
authors.lastname: Tinazzi
authors.forename: Dimitri
authors.initials: D
authors.lastname: Peterlana
authors.forename: Claudio
authors.initials: C
authors.lastname: Lunardi
mesh_terms: D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D011241:Prednisone / Q000009:adverse effects*; D012514:Sarcoma, Kaposi / Q000139:chemically induced* / Q000188:drug therapy; D014747:Vinblastine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D014750:Vincristine; D014747:Vinblastine; D011241:Prednisone