title: The use of desorption/ionization on porous silicon mass spectrometry for the detection of negative ions for fatty acids.
abstract: The study of low molecular weight compounds by matrix-assisted laser desorption/ionization (MALDI) is difficult because of the presence of ions originating from the matrix in the low-m/z range. In order to resolve these problems, new matrix-free approaches were developed based on laser desorption/ionization from the surface of various materials such as graphite and porous silicon. Our work involves the use of 'desorption ionization on porous silicon mass spectrometry' (DIOS-MS) in the negative ion mode to study fatty acid compounds. The potential of the DIOS-MS technique is shown and an insight into the ionization mechanism provided.
authors.affiliation: Equipe de Spectrométrie de masse (LCSOB) UMR 7613 CNRS (Synthèse, Structure et Fonction de Molécules Bioactives), B45, Université Pierre et Marie Curie, 4 place Jussieu, 75252 Paris Cedex 05, France.
authors.forename: Natali
authors.initials: N
authors.lastname: Budimir
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Blais
authors.forename: Françoise
authors.initials: F
authors.lastname: Fournier
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Tabet
mesh_terms: D000838:Anions / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry*; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D012825:Silicon / Q000737:chemistry*
chemical_list: D000838:Anions; D005227:Fatty Acids; D011108:Polymers; D012825:Silicon