title: [Study of gastric function after esophagectomy and cardiectomy with vagus nerve preserved and reconstruction of gastric funds in patients with esophageal and cardiac cancer].
abstract: OBJECTIVE
  To study the gastric function after esophagectomy and cardiectomy with vagus nerve preserved and reconstruction of gastric funds (VPRG)in patients with esophageal cancer (EC) and cardiac cancer (CC).
  
  
  METHODS
  Sixty-eight patients with early or middle staged EC or CC received esophagectomy and cardiectomy with vagus nerve preserved and reconstruction of gastric funds (VPRG),while other 68 patients esophagectomy and cardiectomy with vagus nerve severed and no reconstruction of gastric funds (VSNG) as control. The symptoms,the pressure of the residual esophagus and thoracic stomach, 24-hour pH monitoring, mean basic gastric acid output, gastric emptying time of the intrathoracic stomach,fasting serum gastrin level, fibreoptic endoscopic results were compared before and after operation between the two groups.
  
  
  RESULTS
  The patients with VPRG had less symptoms after operation than those with VSNG such as anorexia, belch, reflux, heartburn, nausea, diarrhea, postcibal satiety (P< 0.01). In VPRG group,compared with the results before operation,there were no significant differences in 24-hour pH monitoring,the mean basic gastric acid output, the fasting serum gastrin level,the gastric emptying time of intrathoracic stomach one month and one year after operation (both P > 0.05). The pressure of the residual esophagus above the anastomosis in VPRG group was significantly higher than that in VSNG group (both P< 0.05). Fibreoptic endoscopic examination revealed higher incidences of postoperative atrophic gastritis and reflux esophagitis in VPRG group one month and one year after operation than those in VSNG group (P< 0.01).
  
  
  CONCLUSIONS
  Preservation of the vagus nerve and reconstruction of gastric funds after esophagectomy and cardiectomy for esophageal and cardiac cancer can prevent digestive disorder and improve the life quality of the patients.
authors.affiliation: Department of Thoracic Surgery, Shandong Tumor Hospital, Jinan 250117, China.
authors.forename: Guo-fan
authors.initials: GF
authors.lastname: Wang
authors.forename: Bai-jiang
authors.initials: BJ
authors.lastname: Zhang
authors.forename: Wen-feng
authors.initials: WF
authors.lastname: Yang
authors.forename: Shao-ping
authors.initials: SP
authors.lastname: Wang
authors.forename: Hong-ming
authors.initials: HM
authors.lastname: Shen
authors.forename: Su-juan
authors.initials: SJ
authors.lastname: Yu
mesh_terms: D000328:Adult; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D013270:Stomach / Q000503:physiopathology*; D014630:Vagus Nerve / Q000601:surgery