Emergence of Enterobacteriaceae isolates producing CTX-M extended-spectrum beta-lactamase in Austria.
Among 149 extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.
Eisner
Alexandra
A
Institute of Hygiene, Medical University of Graz, Universitätsplatz 4, A-8010 Graz, Austria. alexandra.eisner@meduni-graz.at
Fagan
Elizabeth J
EJ
Feierl
Gebhard
G
Kessler
Harald H
HH
Marth
Egon
E
Livermore
David M
DM
Woodford
Neil
N
D016521:Electrophoresis, Gel, Pulsed-Field; D004755:Enterobacteriaceae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D029968:Escherichia coli Proteins / Q000096:biosynthesis; D006801:Humans; D001618:beta-Lactamases / Q000096:biosynthesis*
D029968:Escherichia coli Proteins; C412613:CTX-M-9 protein, E coli; C071167:beta-lactamase CTX-2; C473109:beta-lactamase CTX-M-15; C055184:beta-lactamase TEM-3; D001618:beta-Lactamases