title: Endovascular treatment of cerebral arteriovenous malformations with Onyx embolization.
abstract: BACKGROUND
  In the past 5 years, new treatment materials and techniques offering a different concept in endovascular treatment have been described for cerebral arteriovenous malformations (CAVMs). The aim of this study was to assess the endovascular treatment of CAVMs by using a liquid embolic material, Onyx (Micro Therapeutics. Inc., Irvine, CA, USA).
  
  
  METHODS
  From September 2003 to September 2004, Onyx was used to treat 22 patients with CAVMs. Ten AVMS were located in functional areas, 8 in deep cerebral areas, and 4 in the cerebellar hemisphere. The size of CAVMs was about 3 cm in diameter in 5 patients, 3-6 cm in 11, and more than 6 cm in 6.
  
  
  RESULTS
  In the 22 patients, Onyx embolization was successful. Nidus occlusion was complete in 3 patients, > 90% in 8, > 80% and < 90% in 6, and > 50% and < 80% in 5. Complications included transient neurological deficits in 2 patients, and adherence of microcatheter to the site of injection in 2.
  
  
  CONCLUSIONS
  Being non-adhesiveness, Onyx is a safe and satisfactory embolic material in the treatment of CAVMs. But its long-term efficacy awaits further follow-up.
authors.affiliation: Department of Neurosurgery, Qilu Hospital, Shandong University, Jinan 250012, China.
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: He
authors.forename: Chu-han
authors.initials: CH
authors.lastname: Jiang
authors.forename: Hong-bing
authors.initials: HB
authors.lastname: Liu
authors.forename: You-xiang
authors.initials: YX
authors.lastname: Li
authors.forename: Jing-bo
authors.initials: JB
authors.lastname: Zhang
authors.forename: Zhong-xue
authors.initials: ZX
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D004121:Dimethyl Sulfoxide