[Non-randomized evaluation studies (TREND)].
Nonrandomized intervention trials are needed when randomized clinical trials cannot be performed. To report the results from nonrandomized intervention studies transparently, the TREND (Transparent Reporting of Evaluations with Nonrandomized Designs) checklist should be used. This implies that nonrandomized studies should follow the remaining methodological tools usually employed in randomized trials and that the uncertainty introduced by the allocation mechanism should be explicitly reported and, if possible, quantified.
Vallvé
Carles
C
Farmacólogo clínico, Cardedeu, Barcelona, España. vallve@telefonica.net
Artés
Maite
M
Cobo
Erik
E
D001319:Authorship / Q000592:standards; D057189:Checklist; D002986:Clinical Trials as Topic / Q000592:standards*; D005069:Evaluation Studies as Topic; D010506:Periodicals as Topic / Q000592:standards; D011643:Publishing / Q000592:standards*; D016032:Randomized Controlled Trials as Topic; D058028:Research Report / Q000592:standards*; D011795:Surveys and Questionnaires