title: Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents.
abstract: OXA-58 is a recently described carbapenemase from Acinetobacter spp. in Europe. We examined earlier worldwide Acinetobacter collections and found bla(OXA-58) in 30 carbapenem-nonsusceptible isolates, including several isolates collected in Argentina and Kuwait in 1995 and 1996 and in a British outbreak strain from 2000. Most isolates (28 of 30) also had bla(OXA-51). We conclude that bla(OXA-58) is geographically widespread and has occurred in Acinetobacter spp. for over 10 years.
authors.affiliation: Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, United Kingdom.
authors.forename: Juliana
authors.initials: J
authors.lastname: Coelho
authors.forename: Neil
authors.initials: N
authors.lastname: Woodford
authors.forename: Mariya
authors.initials: M
authors.lastname: Afzal-Shah
authors.forename: David
authors.initials: D
authors.lastname: Livermore
mesh_terms: D000150:Acinetobacter / Q000187:drug effects / Q000201:enzymology*; D001426:Bacterial Proteins / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase