title: Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany).
abstract: The widespread use of cellular telephones has generated concern about possible adverse health effects, particularly brain tumors. In this population-based case-control study carried out in three regions of Germany, all incident cases of glioma and meningioma among patients aged 30-69 years were ascertained during 2000-2003. Controls matched on age, gender, and region were randomly drawn from population registries. In total, 366 glioma cases, 381 meningioma cases, and 1,494 controls were interviewed. Overall use of a cellular phone was not associated with brain tumor risk; the respective odds ratios were 0.98 (95% confidence interval (CI): 0.74, 1.29) for glioma and 0.84 (95% CI: 0.62, 1.13) for meningioma. Among persons who had used cellular phones for 10 or more years, increased risk was found for glioma (odds ratio = 2.20, 95% CI: 0.94, 5.11) but not for meningioma (odds ratio = 1.09, 95% CI: 0.35, 3.37). No excess of temporal glioma (p = 0.41) or meningioma (p = 0.43) was observed in cellular phone users as compared with nonusers. Cordless phone use was not related to either glioma risk or meningioma risk. In conclusion, no overall increased risk of glioma or meningioma was observed among these cellular phone users; however, for long-term cellular phone users, results need to be confirmed before firm conclusions can be drawn.
authors.affiliation: Institute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg-University of Mainz, Mainz, Germany. joachim@cancer.dk
authors.forename: Joachim
authors.initials: J
authors.lastname: Schüz
authors.forename: Eva
authors.initials: E
authors.lastname: Böhler
authors.forename: Gabriele
authors.initials: G
authors.lastname: Berg
authors.forename: Brigitte
authors.initials: B
authors.lastname: Schlehofer
authors.forename: Iris
authors.initials: I
authors.lastname: Hettinger
authors.forename: Klaus
authors.initials: K
authors.lastname: Schlaefer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Wahrendorf
authors.forename: Katharina
authors.initials: K
authors.lastname: Kunna-Grass
authors.forename: Maria
authors.initials: M
authors.lastname: Blettner
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000209:etiology; D016022:Case-Control Studies; D040421:Cell Phone; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D005858:Germany / Q000453:epidemiology; D005910:Glioma / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D015994:Incidence; D007407:Interviews as Topic; D008297:Male; D008579:Meningioma / Q000453:epidemiology* / Q000209:etiology; D008875:Middle Aged; D012042:Registries; D018570:Risk Assessment; D012307:Risk Factors