title: [The peculiarities of separate and combined exposure to low dose-rate gamma-radiation and 232Th nitrate on thyroid gland].
abstract: We studied the effects of both: of the separate and of the combined exposure to gamma-radiation (absorbed doses for 30 days were 1.4-1.8 cGy, for 90 days were 4.3-5.4 cGy) and 232Th nitrate (in concentrations 6.0; 20.0 and 60.0 mg/l) on the CBA line mice thyroid gland. Hat is shown the thyroid gland response to the combined exposure is significant in an appearance of non-linear effects of interaction. The intensiveness of the radiation influence (time and doses) is revealed to affect on the biological response direction in thyroid gland. The intensity of this effect was depended on the correlation between the radiation activity and the chemical components concentration. The dispersive analyses showed that all the studied factors caused structural changes in thyroid gland in this experiment, but the gamma-radiation influence causes the primary contribution.
authors.forename: O V
authors.initials: OV
authors.lastname: Raskosha
authors.forename: O V
authors.initials: OV
authors.lastname: Ermakova
mesh_terms: D000818:Animals; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D017970:Thorium Compounds / Q000494:pharmacology*; D013961:Thyroid Gland / Q000473:pathology / Q000528:radiation effects*
chemical_list: D017970:Thorium Compounds; C036680:thorium nitrate