Efficacy of imiquimod in solitary plaques of mycosis fungoides.
Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. The extent and type of skin involvement (T classification) and presence of lymph node or visceral involvement are important predictors in selecting the type of treatment. Skin directed treatment represents the most appropriate therapy for early stage disease. Current topical treatment including potent topical steroids and nitrogen mustard are associated with adverse effects such as cutaneous atrophy and contact dermatitis. In the present study, we tested the efficacy of imiquimod in mycosis fungoides plaques.
Onsun
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N
Department of Dermatology, Vakif Gureba Teaching Hospital, Istanbul, Turkey. nahide@netone.com.tr
Ufacik
H
H
Kural
Y
Y
Topçu
E
E
Somay
A
A
D000634:Aminoquinolines / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D003879:Dermatologic Agents / Q000494:pharmacology*; D005260:Female; D006801:Humans; D000077271:Imiquimod; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy* / Q000473:pathology* / Q000503:physiopathology
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D003879:Dermatologic Agents; D000077271:Imiquimod