Psychosocial effects of age-related macular degeneration.
BACKGROUND
Age-related macular degeneration (AMD) affects approximately 10% of persons aged 65-74 years and 30% of those aged 75 and older and is the major cause of blindness in old age. AMD is progressive and irreversible.


OBJECTIVE
To review the psychosocial effects of AMD.


METHODS
OVID data bases (MEDLINE, psycINFO and CINAHL) from 1966 to 2004 were reviewed.


RESULTS
AMD is associated with functional impairment, high rates of depression, anxiety and emotional distress and increased mortality. Risk factors for depression are not well-defined, except for the degree of functional impairment and impending or actual loss of vision in the second eye. Behavioral and self-management programs may be effective in managing depression associated with AMD, but few studies have been performed, and none using drugs or multimodal therapy.


CONCLUSIONS
AMD will become even more prevalent as the population ages. Identification of risk factors for psychological consequences and of effective interventions remain to be recognized.
Berman
K
K
Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Randwick, NSW, Australia.
Brodaty
H
H
D000203:Activities of Daily Living / Q000523:psychology; D000342:Affective Symptoms / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D000368:Aged; D001008:Anxiety Disorders / Q000523:psychology / Q000628:therapy; D001766:Blindness / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D006801:Humans; D008268:Macular Degeneration / Q000523:psychology*