title: Structural-functional model of the mitotic chromosome.
abstract: In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.
authors.affiliation: Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
authors.forename: V Yu
authors.initials: VY
authors.lastname: Polyakov
authors.forename: O V
authors.initials: OV
authors.lastname: Zatsepina
authors.forename: I I
authors.initials: II
authors.lastname: Kireev
authors.forename: A N
authors.initials: AN
authors.lastname: Prusov
authors.forename: D I
authors.initials: DI
authors.lastname: Fais
authors.forename: E V
authors.initials: EV
authors.lastname: Sheval
authors.forename: Yu V
authors.initials: YV
authors.lastname: Koblyakova
authors.forename: S A
authors.initials: SA
authors.lastname: Golyshev
authors.forename: Yu S
authors.initials: YS
authors.lastname: Chentsov
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D002843:Chromatin / Q000737:chemistry / Q000648:ultrastructure; D002868:Chromosomal Proteins, Non-Histone / Q000737:chemistry / Q000378:metabolism; D002875:Chromosomes / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D002877:Chromosomes, Human / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D004247:DNA / Q000737:chemistry; D022041:Euchromatin / Q000737:chemistry / Q000378:metabolism; D006570:Heterochromatin / Q000737:chemistry / Q000378:metabolism; D006657:Histones / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007399:Interphase; D008938:Mitosis
chemical_list: D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D022041:Euchromatin; D006570:Heterochromatin; D006657:Histones; D004247:DNA; D002118:Calcium