title: Straightforward three-component palladium-catalysed synthesis of pyridazin-3(2H)-one libraries.
abstract: A simple and straightforward three-component methodology for the solution phase high-throughput synthesis of 2,5-disubstituted pyridazin-3(2H)-one libraries has been developed. The diversity at position 5 of the heterocycle is determined by the use of Suzuki, Sonogashira, Heck or Stille coupling.
authors.affiliation: Departamento de Química Orgánica, Laboratorio de Química Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, Santiago de Compostela 15782, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Coelho
authors.forename: Eddy
authors.initials: E
authors.lastname: Sotelo
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011724:Pyridazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011724:Pyridazines; D010165:Palladium