[Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 49 Tunisian cases].
This is a retrospective study about 49 cases of xeroderma pigmentosum (XP). The goal was to determine the clinical features of XP in Tunisia. Our study revealed the predominance of a moderate form. Malignant skin tumors showed early. Squamous cell carcinoma (SCC) remainsed the most frequent skin malignancy in all clinical forms. Neurological abnormalities were more frequent in the moderate form. Mental retardation and peripheral neuropathy were the most common signs.
Zghal
Mohamed
M
Service de dermatologie, Hôpital Habib Thameur, Tunis.
El-Fekih
Nadia
N
Fazaa
Becima
B
Fredj
Mohamed
M
Zhioua
Raja
R
Mokhtar
Insaf
I
Mrabet
Amel
A
Ferjani
Mohamed
M
Gaigi
Sadok
S
Kamoun
Med Ridha
MR
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005128:Eye Diseases / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology; D012189:Retrospective Studies; D012871:Skin Diseases / Q000209:etiology; D014983:Xeroderma Pigmentosum / Q000150:complications*