Rectal inflammation as first manifestation of graft-vs-host disease: radiologic-pathologic findings.
Graft-vs-host disease (GVHD) is a common, life-threatening complication of bone marrow transplantation that frequently involves the gastrointestinal tract. Since symptoms are typically nonspecific, radiologic examination is often performed to reach a diagnosis. To the best of our knowledge, this is the first reported radiologic description of a case of rectal involvement as the first manifestation of GVHD. The differential diagnosis of segmental rectal wall thickening in a patient following bone marrow transplantation should include GVHD.
Cantisani
Vito
V
Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Mortele
Koenraad J
KJ
Viscomi
Salvatore G
SG
Glickman
Jonathan
J
Silverman
Stuart G
SG
Ros
Pablo R
PR
D015746:Abdominal Pain / Q000175:diagnosis; D000328:Adult; D001706:Biopsy; D016026:Bone Marrow Transplantation; D003287:Contrast Media; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis; D005260:Female; D006086:Graft vs Host Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009190:Myelodysplastic Syndromes / Q000601:surgery; D011349:Proctitis / Q000000981:diagnostic imaging* / Q000473:pathology; D011351:Proctoscopy; D036542:Tomography, Spiral Computed; D014057:Tomography, X-Ray Computed
D003287:Contrast Media