Chronic cutaneous lupus flare induced by systemic 5-fluorouracil.
5-Fluorouracil is an antineoplastic antimetabolite responsible for a variety of cutaneous reactions. We report a case of chronic cutaneous lupus flare related to systemic 5-fluorouracil administration for breast cancer in a patient with documented history of chronic cutaneous lupus.
Kluger
N
N
Department of Dermatology, Hôpital Saint Eloi, Montpellier, France.
Bessis
D
D
Guillot
B
B
D000230:Adenocarcinoma / Q000188:drug therapy; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil