[Assessment of mortality and specific index in acute renal failure].
A variety of systems of risk factor stratification have been studied to predict the outcome in acute renal failure (ARF).


OBJECTIVE
Assess and compare mortality and the Acute Tubular Necrosis Individual Severity Score (ATN-ISS) in patients with AFR treated in a university hospital.


METHODS
A prospective analysis was made of 103 patients with a diagnosis of intrinsic ARF admitted to the Hospital das Clinicas da Faculdade de Medicina de Botucatu, UNESP. Patients were followed up until recovery of renal function or death. The Score ATN-ISS was recorded during the first hours of the assessment by a nephrologist. Results were reported as median or mean +/- SD, with statistical significance of p < 0.05.


RESULTS
Fifty-one percent of patients were male with a mean age of 58 +/- 36 years. Forty-four percent died in the hospital. Mortality was higher in patients from the surgical wards (52.7%) and in patients who were treated with dialysis (63.8%). The score ATN-ISS showed a good confidence level, with high discriminatory power (area under the curve of 0.95) and good accuracy.


CONCLUSIONS
Mortality in this study was comparable to that found in literature. The ATN-ISS was shown to be a prognostic index with a high confidence level that could be routinely applied by nephrologists to patients with AFR.
Balbi
André Luis
AL
Departamento de Clínica Médica, Universidade Estadual Paulista, UNESP, Botucatu, SP.
Gabriel
Daniela Ponce
DP
Barsante
Renata Cristina
RC
Caramori
Jacqueline Teixeira
JT
Martin
Luis Cuadrado
LC
Barreti
Pasqual
P
D058186:Acute Kidney Injury / Q000401:mortality* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D002648:Child; D004812:Epidemiologic Methods; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012737:Sex Factors