title: Cephalosporin resistant Shigella flexneri from a clinical isolate--a rare finding.
abstract: Shigellosis is an important public health problem, especially in developing countries. Antibiotic treatment of dysentery aimed at resolving diarrhea or reducing its duration, and to prevent transmission to other close contacts. Isolates with resistance to first line drugs have been reported throughout world, third generation cephalosporins and quinolones are mainstay of treatment. Shigella flexneri resistant to third generation cephalosporins in a clinical isolate is a rare finding, and this has been reported for the first time in Pakistan.
authors.affiliation: Department of Pathology and Microbiology, The Aga Khan University, Karachi, Pakistan.
authors.forename: Nasim
authors.initials: N
authors.lastname: Sabir
authors.forename: Afia
authors.initials: A
authors.lastname: Zafar
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018550:Cephalosporin Resistance; D002511:Cephalosporins / Q000494:pharmacology*; D004405:Dysentery, Bacillary / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008297:Male; D010154:Pakistan; D012763:Shigella flexneri / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins