title: Some considerations about acquired adult and pediatric cholesteatomas.
abstract: Authors debate about cholesteatomas, from the first time this word was employed, by Muller, in 1838, until the recent updates. They dissert about its definition, etiology and pathology and present basic concepts about its biology. They also make a wide review about pediatric cholesteatoma, its epidemiology and biology, and compare it with adult cholesteatoma. Finally, they describe some articles about ossicle chain erosion and its correlation with cholesteatoma perimatrix, collagen and collagenase.
authors.affiliation: Pediatrics, UFRGS. cristinadornelles@yahoo.com.br
authors.forename: Cristina
authors.initials: C
authors.lastname: Dornelles
authors.forename: Sady S da
authors.initials: SS
authors.lastname: Costa
authors.forename: Luíse
authors.initials: L
authors.lastname: Meurer
authors.forename: Cláudia
authors.initials: C
authors.lastname: Schweiger
mesh_terms: D000328:Adult; D002648:Child; D018424:Cholesteatoma, Middle Ear / Q000145:classification / Q000209:etiology / Q000473:pathology; D006801:Humans