title: [Drug therapy of chronic venous insufficiency with Venza].
abstract: An open prospective study on the use of the drug Venza for complex variceal disease treatment was conducted. The study included 125 patients aged from 21 to 75. The outcome measures were: patient complaints and medical history, as well as Doppler ultrasound of lower limb veins, arteriovenous index (AVI) and leg circumference at the ankle level for the objective assessment of therapeutic effectiveness. Malleolar circumference decreased by average 0.8+/-0.3 cm. The drug therapy resulted in the regression of clinical signs (leg fatigue heaviness and edema, night palsies). Venza had a positive effect on all evaluated parameters of patient's quality of life. Its clinical effectiveness was estimated as "very good" and "good" in 27.5% and 57.5%, respectively. The study proved the Venza's effectiveness in treatment of patients with lower limb chronic venous insufficiency.
authors.forename: L I
authors.initials: LI
authors.lastname: Bogdanets
authors.forename: V S
authors.initials: VS
authors.lastname: Arakelian
authors.forename: S V
authors.initials: SV
authors.lastname: Sapelkin
authors.forename: E V
authors.initials: EV
authors.lastname: Kalinina
mesh_terms: D000328:Adult; D031319:Aesculus; D000368:Aged; D001783:Blood Flow Velocity / Q000187:drug effects / Q000502:physiology; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods*; D028321:Plant Preparations / Q000627:therapeutic use*; D011446:Prospective Studies; D011788:Quality of Life; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D028321:Plant Preparations