title: Control of acute myeloid leukemia morbidity in northwest Iran.
abstract: BACKGROUND
  To investigate protocols of remission induction therapy for prevention of morbidity of acute myeloid leukemia.
  
  
  METHODS
  The responses of 150 patients to "2+5" and "3+7" protocols during 1996-2003 were assessed and analyzed with the Chi-Square method.
  
  
  RESULTS
  Complete remission was observed in 30% of cases treated with 2 days of daunorubicin and 5 days of cytarabine (2+5 regimen). Remission was increased to 52.5% when patients were treated with 3+7 regimens with the same drugs. Partial remission resulted in 25 and 10 percent of cases, respectively.
  
  
  CONCLUSIONS
  As in previous studies the 3+7 regimen was demonstrated to be more effective than the 2+5 regimen in our hospital (p=0.0009).
authors.affiliation: Ghazi Hematology Oncology Research Department, Tabriz University of Medical Sciences, Iran 51665-139. jeziaei@yahoo.com
authors.forename: Jamal
authors.initials: J
authors.lastname: Eivazi-Ziaei
mesh_terms: D000293:Adolescent; D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D003561:Cytarabine / Q000008:administration & dosage*; D003630:Daunorubicin / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D006801:Humans; D007492:Iran; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008875:Middle Aged; D012074:Remission Induction; D012189:Retrospective Studies
chemical_list: D000903:Antibiotics, Antineoplastic; D000964:Antimetabolites, Antineoplastic; D003561:Cytarabine; D003630:Daunorubicin