title: Association of estrogen receptor-alpha genepolymorphisms with venous thrombosis.
abstract: XbaI and PvuII polymorphisms of the estrogen receptor-alpha gene (ERalpha) have been associated with several multifactorial diseases. We studied the distribution of ERalpha polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.
authors.forename: Federico
authors.initials: F
authors.lastname: Lussana
authors.forename: Elena M
authors.initials: EM
authors.lastname: Faioni
authors.forename: Carmelo
authors.initials: C
authors.lastname: Mavilia
authors.forename: Paolo
authors.initials: P
authors.lastname: Bucciarelli
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Brandi
authors.forename: Marco
authors.initials: M
authors.lastname: Cattaneo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D015252:Deoxyribonucleases, Type II Site-Specific; D047628:Estrogen Receptor alpha / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D012737:Sex Factors; D020246:Venous Thrombosis / Q000235:genetics*
chemical_list: D047628:Estrogen Receptor alpha; C025580:endodeoxyribonuclease XBAI; C025630:CAGCTG-specific type II deoxyribonucleases; D015252:Deoxyribonucleases, Type II Site-Specific