title: Sarcoidosis in chronic granulomatous disease.
abstract: In addition to increased susceptibility to infections in patients with chronic granulomatous disease (CGD), a higher incidence of sterile inflammatory disorders in these patients has been noted. However, sarcoidosis has not been reported previously in CGD. In this report, we describe two patients who have CGD and a disorder consistent with sarcoidosis on the basis of unequivocal clinical-radiographic presentations, their responses to treatment, and serum angiotensin-converting enzyme levels. Serum angiotensin-converting enzyme levels were measured in 26 other patients with CGD to establish an appropriate reference range. A possible relationship between CGD and sarcoidosis is discussed.
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Suk See
authors.initials: SS
authors.lastname: De Ravin
authors.forename: Nora
authors.initials: N
authors.lastname: Naumann
authors.forename: Michael R
authors.initials: MR
authors.lastname: Robinson
authors.forename: Karyl S
authors.initials: KS
authors.lastname: Barron
authors.forename: David E
authors.initials: DE
authors.lastname: Kleiner
authors.forename: Jean
authors.initials: J
authors.lastname: Ulrick
authors.forename: Julia
authors.initials: J
authors.lastname: Friend
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Anderson
authors.forename: Dirk
authors.initials: D
authors.lastname: Darnell
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Kang
authors.forename: Harry L
authors.initials: HL
authors.lastname: Malech
mesh_terms: D000293:Adolescent; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis; D002648:Child; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000175:diagnosis