title: Transient aquagenic palmar hyperwrinkling: the first instance reported in a young boy.
abstract: Transient reactive papulotranslucent acrokeratoderma is a rare palmoplantar keratoderma seen predominantly in adolescent and young adult women. Clinically it is characterized by translucent white papules generally involving the palmar surfaces after exposure to water. The typical "hands-in-the-bucket" sign, which is not clearly visible until the hand is submerged in water, is indispensable for the diagnosis. Histologic examination shows a mild orthokeratotic hyperkeratosis and dilated eccrine ducts. We propose the term "transient aquagenic palmar hyperwrinkling" to describe this condition. Until now, a total of 12 patients have been reported in the literature, all female, with an age of onset from 9 to 33 years. We present the first reported instance of this condition in a young boy.
authors.affiliation: Department of Clinical and Experimental Medicine, Section of Dermatology, University of the Study of Bologna, Italy.
authors.forename: Iria
authors.initials: I
authors.lastname: Neri
authors.forename: Federica
authors.initials: F
authors.lastname: Bianchi
authors.forename: Annalisa
authors.initials: A
authors.lastname: Patrizi
mesh_terms: D000169:Acrodermatitis / Q000209:etiology / Q000473:pathology*; D001707:Biopsy, Needle; D002648:Child; D004439:Eccrine Glands / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007101:Immersion / Q000009:adverse effects; D007150:Immunohistochemistry; D007645:Keratoderma, Palmoplantar / Q000209:etiology / Q000473:pathology*; D008297:Male; D035583:Rare Diseases; D012008:Recurrence; D018570:Risk Assessment; D012720:Severity of Illness Index; D014867:Water / Q000009:adverse effects*
chemical_list: D014867:Water