title: [Lymphoma's manifestations in Sjögren's syndrome: is there a relation?].
abstract: Sjögren's Syndrome (SS) is considered a multisystemic chronic disorder, which is characterized by a lymphocytic infiltration of exocrine glands and autoantibodies production.
  
  
  OBJECTIVE
  Several studies have demonstrated increased incidence of Lymphoma in SS patients. Our study tries to determine this relation.
  
  
  METHODS
  Transversal cohort.
  
  
  METHODS
  Patients with Sicca's Syndrome from the Stomathology service, Santa Casa de Misericórdia Hospital, in Sao Paulo, ENT Department, from July 1999 to April 2002.
  
  
  RESULTS
  Out of 39 patients, 24 were diagnose as SS. Ages ranged from 19 to 83 years old, with predominance of women (69.7%). Time between the first symptoms and SS diagnosis were variable, ranging within 3.77 years. None of the analyzed patients developed lymphoma.
  
  
  CONCLUSIONS
  Both SS early diagnosis and the increased risk of lymphoma's development in those patients are important, reason why long-term follow-up is essential. We observed that our findings were different from those in the literature. We did not detect any cases of lymphoma in our patients.
authors.affiliation: Faculdade de Ciências Médicas de São Paulo.
authors.forename: Fabrícia Dias Colombano
authors.initials: FD
authors.lastname: Limares
authors.forename: Rita De Cássia
authors.initials: Rde C
authors.lastname: Soler
authors.forename: Ivo
authors.initials: I
authors.lastname: Bussoloti Filho
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013997:Time Factors