Oral histoplasmosis in an HIV-negative patient.
Histoplasmosis is a deep mycosis caused by Histoplasma capsulatum, which has been found in soil with accumulated excreta of bats and birds. This disease has variable clinical findings with only pulmonary or systemic involvement. Upper aerodigestive lesions are found mainly associated with systemic disease, affecting particularly patients with immunosuppression conditions mainly caused by HIV. However, it is uncommon in immunocompetent patients. This report describes a case of oro-laryngeal-esophageal histoplasmosis in a HIV-seronegative patient without detectable systemic involvement.
Alcure
Mônica Leal
ML
Department of Oral Diagnosis, Dental School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
Di Hipólito Júnior
Oswaldo
O
Almeida
Oslei Paes de
OP
Bonilha
Hamilton
H
Lopes
Márcio Ajudarte
MA
D000935:Antifungal Agents / Q000627:therapeutic use; D004935:Esophageal Diseases / Q000188:drug therapy / Q000473:pathology; D018023:HIV Seronegativity; D006660:Histoplasmosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D009960:Oropharynx / Q000473:pathology; D010608:Pharyngeal Diseases / Q000188:drug therapy / Q000473:pathology
D000935:Antifungal Agents; D017964:Itraconazole