title: Optimal designs in stability studies.
abstract: New optimality criteria for stability studies are proposed, and the related optimal designs are investigated. For each optimality criterion, optimal designs are identified within a class of competing designs. The property of the optimal designs for detecting slope differences is discussed.
authors.affiliation: Mathematics, Statistics and Computer Science Department, University of Illinois at Chicago, Chicago, Illinois, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Hedayat
authors.forename: Xu
authors.initials: X
authors.lastname: Yan
authors.forename: Lawrence
authors.initials: L
authors.lastname: Lin
mesh_terms: D004345:Drug Industry; D004355:Drug Stability; D015233:Models, Statistical; D012107:Research Design