In117, an unusual In0-like class 1 integron containing CR1 and bla(CTX-M-2) and associated with a Tn21-like element.
An unusual In0-like class 1 integron containing a common region that includes the putative recombinase gene named orf513 (CR1) and bla(CTX-M-2) was characterized from Escherichia coli. The integron contained an unusual gene cassette array, estX-aadA1, embedded between the 5'-conserved segment (5'-CS) and 3'-CS1 regions and was flanked by mer-Tn21 sequences downstream of the tni truncated module. This element constitutes one of the few examples of CR1-bearing class 1 integrons that has been fully characterized.
Valverde
Aránzazu
A
Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain.
Cantón
Rafael
R
Galán
Juan Carlos
JC
Nordmann
Patrice
P
Baquero
Fernando
F
Coque
Teresa M
TM
D001483:Base Sequence; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D032023:Integrons; D008969:Molecular Sequence Data; D001618:beta-Lactamases / Q000235:genetics*
D004251:DNA Transposable Elements; C071167:beta-lactamase CTX-2; D001618:beta-Lactamases