Magnesium profile in autism.
The aim of the present study was to determine and compare plasma and erythrocyte concentrations of magnesium in 12 autistic children (10 boys, 2 girls), 17 children with other autistic spectrum disorders (14 boys, 3 girls), 5 girls with classic Rett syndrome, and 14 normal children (7 boys, 7 girls) of the same age. No differences in intracellular Mg were found between controls and pathological subjects; however, autistic children and children with other autistic spectrum disorders had significantly lower plasma concentrations of Mg than normal subjects (p=0.013 and p=0.02, respectively). Although our study population was small, we conclude that children with autistic spectrum disorders require special dietary management. If these cases are diagnosed at an early stage, they can be helped through diet.
Strambi
Mirella
M
Department of Paediatrics, Obstetrics and Reproductive Medicine, Section of Neonatology and Preventive Paediatrics, Azienda Universitaria Ospedaliera Senese, Policlinico Le Scotte, Siena, Italy. strambi@umisit.it
Longini
Mariangela
M
Hayek
Joseph
J
Berni
Silvia
S
Macucci
Francesca
F
Scalacci
Elisa
E
Vezzosi
Piero
P
D000293:Adolescent; D001321:Autistic Disorder / Q000097:blood* / Q000178:diet therapy; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003627:Data Interpretation, Statistical; D019587:Dietary Supplements; D004912:Erythrocytes / Q000737:chemistry*; D005260:Female; D006801:Humans; D007223:Infant; D008274:Magnesium / Q000097:blood* / Q000627:therapeutic use; D008297:Male; D015518:Rett Syndrome / Q000097:blood / Q000178:diet therapy
D008274:Magnesium