title: [Surgical treatment for stage IV lung cancer].
abstract: OBJECTIVE
  To find out the optimal surgical indication in stage IV lung cancer patients, we evaluated them retrospectively.
  
  
  RESULTS
  From 1975 to 2005, 62 patients without multiple metastases were operated at our hospital. The most common histological type was adenocarcinoma (67.7%). The metastatic lesions were lung (33.9%), brain (24.2%), liver, bone, adrenal gland and so on. The overall survival rate of stage IV lung cancer was 10.4% at 5-year. Five-year survival for patients with lung or brain metastasis who had no lymph node metastasis were significantly more superior than those with lymph node metastasis (p=0.0389, 0.0021). Four of 62 patients had 5-year survival. Two were lung and the others were brain and adrenal gland metastasis without lymph node metastasis.
  
  
  CONCLUSIONS
  Stage IV lung cancer with lung or brain or adrenal gland metastasis without lymph node metastasis should be resected.
authors.affiliation: Division of Surgical Oncology, Nagasaki University Graduate School of Medicine, Nagasaki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyazaki
authors.forename: T
authors.initials: T
authors.lastname: Tagawa
authors.forename: A
authors.initials: A
authors.lastname: Nakamura
authors.forename: N
authors.initials: N
authors.lastname: Yamasaki
authors.forename: S
authors.initials: S
authors.lastname: Hashizume
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Taguchi
authors.forename: S
authors.initials: S
authors.lastname: Morino
authors.forename: T
authors.initials: T
authors.lastname: Nagayasu
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000401:mortality / Q000556:secondary; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000401:mortality; D012189:Retrospective Studies; D016019:Survival Analysis