GIST: a clinical dilemma.
The authors report a clinical case of malignant gastric and duodenojejunal GIST, in which the only surgical treatment seems to be definitive. In a 69-year-old female, a surgical resection of the gastric and duodenojejunal tumor was performed. Histological analysis showed two spindle cells stromal tumors with mitotic rate >20/10 HPF and its uncommitted origin was demonstrated. Despite the high malignancy degree, the patient refused chemotherapy treatment and there were no local recurrence nor metastasis at a follow-up of 8 years. For this reason and because of the uncertain behavior of histologically benign GIST, the authors propose a lifelong follow-up of all patients managed with potentially curative surgical resection.
Pisanu
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Dipartimento Chirurgico, Materno-Infantile e di Scienze dell'lmmagine, Sezione di Semeiotica Chirurgica, Università degli Studi di Cagliari.
Cillara
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N
Montisci
A
A
Ongetta
P
P
Uccheddu
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A
D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans