title: Coronary artery bypass grafting within the first year after treatment of large acute myocardial infarctions with angioplasty or fibrinolysis.
abstract: OBJECTIVE
  To calculate the incidence and analyse and outcome after coronary artery bypass grafting (CABG) within the first year after randomisation of 1,572 patients with acute myocardial infarctions with ST-segment elevation (STEMI) to either percutaneous coronary intervention (PCI) or fibrinolysis.
  
  
  METHODS
  The study includes 131 patients: 108 male and 23 female with a mean age 62 years.
  
  
  RESULTS
  The total 30-day mortality after CABG was 4.6% (7.5% in the PCI group and 2.6% in the fibrinolysis group). The 30-day mortality was 9.8% after CABG within the first 30-days and 1.3% after CABG within 31-365 days. The patients who were operated early had a reduced EF to 43% as compared to 50% in patients who were not operated or patients having CABG after 30-days (p=0.002).
  
  
  CONCLUSIONS
  CABG was performed within the first year after STEMI in 10% of patients randomised to fibrinolysis and in 6.7% of patients randomised to PCI. Patients having CABG within the first 30-days after treatment of STEMI had an increased mortality of 9.8%.
authors.affiliation: Department of Cardiothoracic Surgery, Gentofte Hospital, 2900 Hellerup, Denmark. hekja@gentoftehosp.kbhamt.dk
authors.forename: Henrik K
authors.initials: HK
authors.lastname: Kjaergard
authors.forename: Per Hostrup
authors.initials: PH
authors.lastname: Nielsen
authors.forename: Jan Jesper
authors.initials: JJ
authors.lastname: Andreasen
authors.forename: Daniel
authors.initials: D
authors.lastname: Steinbrüchel
authors.forename: Lars Ib
authors.initials: LI
authors.lastname: Andersen
authors.forename: Klaus
authors.initials: K
authors.lastname: Rasmussen
authors.forename: Henning Rud
authors.initials: HR
authors.lastname: Andersen
authors.forename: Torsten Toftegaard
authors.initials: TT
authors.lastname: Nielsen
authors.forename: Leif Spange
authors.initials: LS
authors.lastname: Mortensen
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001026:Coronary Artery Bypass / Q000401:mortality / Q000706:statistics & numerical data; D023903:Coronary Restenosis / Q000601:surgery*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic; D013318:Stroke Volume; D016019:Survival Analysis; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents