title: [Genetic polymorphism of six short tandem repeat loci on the X chromosome in a Han race population in China].
abstract: OBJECTIVE
  To investigate the alleles and genotype frequencies of 6 short tandem repeat (STR) loci DXS7130, DXS1214, DXS6799, DXS6804, DXS7424 and DXS7133 on the X chromosome in Chinese Han individuals living in Shaanxi province of Northwest China.
  
  
  METHODS
  The 6 X-chromosomal STR loci were typed by PCR, denatured polyacylamide gel electrophoresis and silver stain.
  
  
  RESULTS
  Among females from Xi'an Han population, the numbers of alleles in the 5 loci (DXS7130, DXS6799, DXS6804, DXS7424 and DXS7133) were detected to be 9, 6, 6, 7, and 7 respectively; the numbers of genotypes were 21, 14, 15, 17 and 12 respectively; and the number of alleles in the DXS1214 was 8. Exact tests demonstrated that genotype frequencies of females had no departure from Hardy-Weinberg equilibrium.
  
  
  CONCLUSIONS
  The six loci of X-chromosomal STRs are appropriate for individual identification, paternity test involving in female child and for study in related disease.
authors.affiliation: Key Laboratory of National Ministry of Health for Forensic Sciences & Environment and Genes, Diseases Key Laboratory of the Education Ministry, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R.China.
authors.forename: Xue
authors.initials: X
authors.lastname: Feng
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Fan
authors.forename: Bing
authors.initials: B
authors.lastname: Yu
authors.forename: Sheng-bin
authors.initials: SB
authors.lastname: Li
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D041321:Chromosomes, Human, X / Q000235:genetics*; D005006:Ethnicity; D005260:Female; D005828:Genetics, Population; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D011153:Population; D020080:Tandem Repeat Sequences / Q000235:genetics*