title: Evaluation of esophageal peristalsis in patients with esophageal tumors: initial experience with cine MR imaging.
abstract: We evaluated esophageal peristalsis in patients with esophageal tumors by cine MR using steady-state free precession (SSFP) sequence and correlated the alteration of the esophageal peristalsis with clinical symptoms and tumor stages. Thirteen patients with pathologically proven esophageal tumors, including 12 esophageal cancers and one submucosal leiomyoma, underwent cine MRI using true fast imaging with steady precession (trueFISP) sequence, which is one SSFP sequence, after contrast-enhanced MR scanning for clinical purposes. A total of 120 serial images were obtained within 60 s through the plane along the long axis of the esophagus while patients chewed gum. The serial trueFISP images were evaluated for the presence, frequency, speed of progression, and passage of peristalsis through the tumor. The data from cine MRI were compared with clinical symptoms and tumor stages. Peristalsis was clearly identified in all patients. Seven patients with complete interruption of peristalsis had dysphagia; one with partially impaired peristalsis could intake solid foods with discomfort; and two with partially impaired peristalsis and three with preserved peristalsis remained asymptomatic. Patients with complete or partial interruption of peristalsis had Stage T3 or T4 esophageal cancer. In conclusion, trueFISP cine MR imaging enables direct visualization of esophageal peristalsis in relation to esophageal tumors. Complete interruption of peristalsis causes dysphagia, whereas partial interruption of and preserved peristalsis usually do not cause digestive problems. Interruption of peristalsis may indicate impaired muscle function caused by invasion of advanced esophageal cancers.
authors.affiliation: Department of Radiology, Kyoto University Hospital, Japan. montpeti@kuhp.kyoto-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Koyama
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Umeoka
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Saga
authors.forename: Go
authors.initials: G
authors.lastname: Watanabe
authors.forename: Ken
authors.initials: K
authors.lastname: Tamai
authors.forename: Ari
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Akira
authors.initials: A
authors.lastname: Hiraga
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Shimada
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
mesh_terms: D004938:Esophageal Neoplasms / Q000473:pathology / Q000503:physiopathology*; D004947:Esophagus / Q000503:physiopathology*; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008409:Mastication; D008875:Middle Aged; D009367:Neoplasm Staging; D010528:Peristalsis / Q000502:physiology*