title: Administer single-site 30-mL intramuscular injection?
abstract: A physician orders fosphenytoin to be administered intramuscularly in a dosage of 30 mL in volume. A change in the traditional practice of limiting intramuscular injection volumes to 5 mL in adult patients is discussed.
authors.affiliation: Presbyterian Hospital, Plano, TX, USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Harrington
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects / Q000379:methods / Q000451:nursing; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D011355:Prodrugs / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D000927:Anticonvulsants; D011355:Prodrugs; D010672:Phenytoin; C043114:fosphenytoin