title: Cytotoxic pregnane steroids from the formosan soft coral Stereonephthya crystalliana.
abstract: Nine new steroids, stereonsteroids A-I (1-9), were isolated from the methylene chloride solubles of the Formosan soft coral Stereonephthya crystalliana Kükenthal. The structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
authors.affiliation: Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China.
authors.forename: Shang-Kwei
authors.initials: SK
authors.lastname: Wang
authors.forename: Chang-Feng
authors.initials: CF
authors.lastname: Dai
authors.forename: Chang-Yih
authors.initials: CY
authors.lastname: Duh
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007941:Leukemia P388; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013624:Taiwan; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D011278:Pregnanes; D013256:Steroids