title: Group o human immunodeficiency virus type 1 infection that escaped detection in two immmunoassays.
abstract: We report a case of human immunodeficiency virus type 1 group O infection not detected by two highly sensitive immunoassays. The sera were strongly reactive to the V3 peptide of group O but not to the gp41 immunodominant epitope. Gp41 was sequenced, confirming that this virus belonged to group O.
authors.affiliation: Department of Biology, Hopital de Versailles, 177 Rue de Versailles, Le Chesnay 78150, France.
authors.forename: Said
authors.initials: S
authors.lastname: Zouhair
authors.forename: Sylvie
authors.initials: S
authors.lastname: Roussin-Bretagne
authors.forename: Alain
authors.initials: A
authors.lastname: Moreau
authors.forename: Sylvie
authors.initials: S
authors.lastname: Brunet
authors.forename: Syria
authors.initials: S
authors.lastname: Laperche
authors.forename: Michèle
authors.initials: M
authors.lastname: Maniez
authors.forename: Francis
authors.initials: F
authors.lastname: Barin
authors.forename: Martine
authors.initials: M
authors.lastname: Harzic
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D014644:Genetic Variation; D015483:HIV Antibodies / Q000097:blood*; D015699:HIV Envelope Protein gp120 / Q000276:immunology; D015700:HIV Envelope Protein gp41 / Q000737:chemistry / Q000235:genetics / Q000276:immunology; D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D015497:HIV-1 / Q000145:classification* / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007118:Immunoassay; D016056:Immunodominant Epitopes / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000821:virology; D012703:Serotyping
chemical_list: D015483:HIV Antibodies; D015699:HIV Envelope Protein gp120; D015700:HIV Envelope Protein gp41; C059762:HIV envelope protein gp120 (305-321); D016056:Immunodominant Epitopes; D010446:Peptide Fragments