title: The effects of creatine supplementation on performance during the repeated bouts of supramaximal exercise.
abstract: OBJECTIVE
  The aim of this study was to investigate the effects of creatine supplementation on performance during the repeated bouts of supramaximal exercise.
  
  
  METHODS
  Twenty-three untrained young males participated in the study. A double blind design was used to create the creatine and placebo groups. Wingate test was performed 5 times with 90 g x kg(-1) body weight load with 2-min intervals. Peak power, mean power (MP), fatigue index (FI) were calculated. Capillary blood samples for lactate analysis were taken during the initial rest period and soon after the fifth Wingate test. For 6 days the creatine group (n=12) ingested 5 g creatine monohydrate, the placebo group (n=11) a flavored drink without creatine monohydrate 4 times daily. On the 7th day, the Wingate tests were repeated, as was the 1st day.
  
  
  RESULTS
  In the creatine group, MP in the 3rd and 4th Wingate test, in the placebo group FI in the 1st and 2nd Wingate test significantly increased. While the total power output obtained from the five Wingate tests increased 7.6% from 366.3+/-65 W to 394+/-67.1 W, there was no change in the placebo group.
  
  
  CONCLUSIONS
  It is concluded that creatine supplementation enhances total power output during the repeated bouts of supramaximal exercise separated by short resting intervals.
authors.affiliation: Department of Physiology, Meram Faculty of Medicine, Selçuk University, Konya, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Okudan
authors.forename: H
authors.initials: H
authors.lastname: Gokbel
mesh_terms: D000293:Adolescent; D000328:Adult; D015308:Anaerobic Threshold / Q000187:drug effects; D001642:Bicycling / Q000502:physiology; D003401:Creatine / Q000494:pharmacology*; D019587:Dietary Supplements; D004311:Double-Blind Method; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006801:Humans; D008297:Male; D018763:Muscle Fatigue / Q000187:drug effects*; D018482:Muscle, Skeletal / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects*; D010725:Phosphocreatine / Q000096:biosynthesis; D005082:Physical Exertion / Q000187:drug effects*
chemical_list: D010725:Phosphocreatine; D003401:Creatine