title: Cysteine-derived s-protected oxazolidinones: potential chemical devices for the preparation of peptide thioesters.
abstract: [reaction: see text]. An N-S acyl-transfer-mediated preparation of peptide thioesters using the S-protected oxazolidinone derived from cysteine has been developed and applied to the synthesis of a 32-mer biologically active peptide by native chemical ligation protocols.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ohta
authors.forename: Saori
authors.initials: S
authors.lastname: Itoh
authors.forename: Akira
authors.initials: A
authors.lastname: Shigenaga
authors.forename: Saori
authors.initials: S
authors.lastname: Shintaku
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Fujii
authors.forename: Akira
authors.initials: A
authors.lastname: Otaka
mesh_terms: D003545:Cysteine / Q000737:chemistry*; D004952:Esters; D015394:Molecular Structure; D023303:Oxazolidinones / Q000138:chemical synthesis* / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D013457:Sulfur Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004952:Esters; D023303:Oxazolidinones; D010455:Peptides; D013457:Sulfur Compounds; D003545:Cysteine