title: Drugs and hormones used to treat pediatric and adolescent reproductive endocrine disorders.
abstract: Pediatric and adolescent reproductive endocrine disorders represent a myriad of diseases including cryptorchidism, male and female sex steroid deficiencies, precocious puberty, and polycystic ovarian syndrome. While there are many traditional therapeutic interventions, some disorders now benefit from new medications or formulations. In this article, we review the most commonly used pharmacological therapies for these disorders and discuss treatment controversies and toxicities.
authors.affiliation: Division of Pediatric Endocrinology and Metabolism, Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA.
authors.forename: Rose A
authors.initials: RA
authors.lastname: Gubitosi-Klug
authors.forename: Alejandro
authors.initials: A
authors.lastname: Martinez
authors.forename: Veronica
authors.initials: V
authors.lastname: Mericq
authors.forename: Mark R
authors.initials: MR
authors.lastname: Palmert
mesh_terms: D000293:Adolescent; D002648:Child; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006058:Gonadal Disorders / Q000188:drug therapy*; D006727:Hormone Antagonists / Q000627:therapeutic use*; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D012098:Reproduction
chemical_list: D004791:Enzyme Inhibitors; D006727:Hormone Antagonists; D006728:Hormones; D007004:Hypoglycemic Agents