title: [Breast cancer and pregnancy: a study of 3 cases].
abstract: Cancer is rare during pregnancy. Breast cancer is the most common cancer in pregnant women. We report 3 cases of breast cancer associated with pregnancy. The mean age was of 34 years. Cancer was detected during the second trimester of pregnancy in two patients. They were treated with mastectomy followed by 6 courses of adjuvant chemotherapy. The first course was given before delivery. Loco regional radiotherapy was given after the end of chemotherapy. The third patient presented with a bilateral breast cancer which was discovered 2 months after delivery. The patient was treated with mastectomy of the left breast and conservative surgery of the right one, associated with adjuvant chemotherapy and radiotherapy. Two patients died the course of the disease. Twenty months later, the third patient is still alive, free of all symptoms and signs. Based on our findings and through a review of literature, we try to determine the epidemiological and clinical features of this association as well the outcome of therapy and eventual prognosis.
authors.affiliation: Service De Carcinologie Médicale, CHU Habib Bourguiba Sfax.
authors.forename: Afef
authors.initials: A
authors.lastname: Khanfir
authors.forename: Moez
authors.initials: M
authors.lastname: Meziou
authors.forename: Faouzi
authors.initials: F
authors.lastname: Bouzid
authors.forename: Jamel
authors.initials: J
authors.lastname: Daoud
authors.forename: Mounir
authors.initials: M
authors.lastname: Frikha
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy