[Scanning electron microscopic study of titanium-hydroxyapatite, the functionally graded-material implanted in rabbits].
OBJECTIVE
The purpose of this study was to observe the tissue tolerance of Ti-HA functionally graded-material (FGM) and the form of the material-bone interface.


METHODS
The sintered Ti -HA FGM, pure HA and pure Ti were respectively implanted into the parietal bone of rabbits. The specimens were observed by SEM at 2, 4, 8 postoperative weeks.


RESULTS
In the early stage, the new bone surrounding the Ti -HA FGM formed earlier with larger amount and better maturity than the pure Ti. The condition was similar to the pure HA. Two months after the operation, direct bonding of material-bone interface was formed between the Ti -HA FGM and the new bone as an integral body. However, there was a little space left between the new bone and the pure Ti.


CONCLUSIONS
The Ti -HA FGM has good tissue tolerance. Its early integration with bone is similar to pure HA and better than pure Ti.
Tang
Xiao-jun
XJ
Plastic Surgery Hospital, Beijing, China.
Xing
Shu-zhong
SZ
Song
Xiao-ling
XL
Gui
Lai
L
Chu
Cheng-lin
CL
D000818:Animals; D018786:Bone Substitutes / Q000737:chemistry*; D005260:Female; D006882:Hydroxyapatites / Q000737:chemistry*; D008297:Male; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration; D011817:Rabbits; D014025:Titanium / Q000737:chemistry*
D018786:Bone Substitutes; D006882:Hydroxyapatites; C098170:hydroxyapatite-titanium alloy; D014025:Titanium