title: [The great important of tumor-free margins in the breast-saving procedure].
abstract: There is increasing evidence that local recurrence after breast-conserving surgery may lead to an increase in distant metastases and disease-specific mortality. The most important factor responsible for recurrence is the margin status after excision. The treatment of patients with breast cancer should be decided upon by a multidisciplinary treatment group so that the candidates for a breast-conserving procedure can be adequately selected with emphasis on achieving maximum local control.
authors.affiliation: Universitair Medisch Centrum St Radboud, afd. Heelkunde, Postbus 9101, 6500 HB Nijmegen. t.wobbes@chir.umcn.nl
authors.forename: T
authors.initials: T
authors.lastname: Wobbes
mesh_terms: D000367:Age Factors; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental / Q000009:adverse effects; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D018579:Patient Selection