title: Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure.
abstract: Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems. Failure of antimonials or severe toxicity is particularly troublesome in patients with renal insufficiency. We report a case of visceral leishmaniasis and renal insufficiency successfully treated with fluconazole and allopurinol for 4 months.
authors.affiliation: Departments of Nephrology, School of Medicine, Pamukkale University, Denizli, Turkey. murcol@mynet.com
authors.forename: Murat
authors.initials: M
authors.lastname: Colakoglu
authors.forename: Guzin Fidan
authors.initials: GF
authors.lastname: Yaylali
authors.forename: Nagihan Yalcin
authors.initials: NY
authors.lastname: Colakoglu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yilmaz
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D000963:Antimetabolites / Q000627:therapeutic use*; D003928:Diabetic Nephropathies / Q000150:complications; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000150:complications*
chemical_list: D000935:Antifungal Agents; D000963:Antimetabolites; D000493:Allopurinol; D015725:Fluconazole