Palladium(II)-catalyzed aerobic dialkoxylation of styrenes: a profound influence of an o-phenol.
We report a Pd(II)-catalyzed aerobic dialkoxylation of styrene derivatives that requires an o-phenol. Initial scope and preliminary mechanistic studies are presented in which the o-phenol is proposed to facilitate the formation of a quinone methide intermediate.
Schultz
Mitchell J
MJ
Department of Chemistry, University of Utah 315 South 1400 East, Salt Lake City, Utah 84112, USA.
Sigman
Matthew S
MS
D000478:Alkylation; D002384:Catalysis; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*
D010636:Phenols; D013343:Styrenes; D010165:Palladium; D010100:Oxygen