Myocardial infarction after taking zolmitriptan.
We report the case of a patient with mild non-obstructive coronary artery disease who sustained an inferior wall myocardial infarction shortly after taking zolmitriptan as abortive therapy for migraine headaches. A Medline search was performed to review all reported cases of myocardial infarction related to migraine therapy with zolmitriptan and related medications. Zolmitriptan may cause myocardial infarction (MI) even in the absence of significant coronary artery disease.
Pacheco-Coronado
Roberto
R
Rush University Medical Center, Chicago, Illinois, USA.
McMullan
Paul W
PW
Galbut
Brian H
BH
Galbut
Erica J
EJ
Snell
Jeffrey
J
Schaer
Gary L
GL
Kavinsky
Clifford J
CJ
D000368:Aged; D003324:Coronary Artery Disease / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy*; D009203:Myocardial Infarction / Q000139:chemically induced*; D023303:Oxazolidinones / Q000009:adverse effects* / Q000627:therapeutic use; D017366:Serotonin Receptor Agonists / Q000009:adverse effects; D014363:Tryptamines / Q000009:adverse effects* / Q000627:therapeutic use
D023303:Oxazolidinones; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C089750:zolmitriptan