title: Tumoral stroma of salivary pleomorphic adenoma -- histopathological, histochemical and immunohistochemical study.
abstract: The aims of our paper were to establish the main histopathological, histochemical and immunohistochemical aspects of tumoral stroma from salivary pleomorphic adenomas. For this purpose we investigated 103 cases by the classical histopathological technique with paraffin embedding and staining with Hematoxylin-Eosin (HE), Hematoxylin-Eosin-Safranin (HES), trichromic Masson, trichromic Goldner Szeckelly, orcein and Periodic Acid Schiff-Blue Alcian (PAS-AA). Immunohistochemically, they were investigated for AE1-AE3, MNF116, CK8, EMA, vimentin, alpha-actin calponin, S-100, GFAP, collagen IV, and PCNA. The results of our study suggest the key role of neoplastic myoepithelial cell in the achievement of diverse morphological aspects of stroma in such neoplasms.
authors.affiliation: Department of Pathology, Emergency County Hospital, University of Medicine and Pharmacy of Craiova. mclaudiu@umfcv.ro
authors.forename: Cl
authors.initials: C
authors.lastname: Mărgăritescu
authors.forename: M
authors.initials: M
authors.lastname: Raica
authors.forename: Cristiana
authors.initials: C
authors.lastname: Simionescu
authors.forename: L
authors.initials: L
authors.lastname: Mogoantă
authors.forename: M
authors.initials: M
authors.lastname: Surpăţeanu
authors.forename: F
authors.initials: F
authors.lastname: Jaubert
authors.forename: Fl
authors.initials: F
authors.lastname: Bogdan
mesh_terms: D008949:Adenoma, Pleomorphic / Q000145:classification / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000145:classification / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology*