[Lymphoma's manifestations in Sjögren's syndrome: is there a relation?].
Sjögren's Syndrome (SS) is considered a multisystemic chronic disorder, which is characterized by a lymphocytic infiltration of exocrine glands and autoantibodies production.


OBJECTIVE
Several studies have demonstrated increased incidence of Lymphoma in SS patients. Our study tries to determine this relation.


METHODS
Transversal cohort.


METHODS
Patients with Sicca's Syndrome from the Stomathology service, Santa Casa de Misericórdia Hospital, in Sao Paulo, ENT Department, from July 1999 to April 2002.


RESULTS
Out of 39 patients, 24 were diagnose as SS. Ages ranged from 19 to 83 years old, with predominance of women (69.7%). Time between the first symptoms and SS diagnosis were variable, ranging within 3.77 years. None of the analyzed patients developed lymphoma.


CONCLUSIONS
Both SS early diagnosis and the increased risk of lymphoma's development in those patients are important, reason why long-term follow-up is essential. We observed that our findings were different from those in the literature. We did not detect any cases of lymphoma in our patients.
Limares
Fabrícia Dias Colombano
FD
Faculdade de Ciências Médicas de São Paulo.
Soler
Rita De Cássia
Rde C
Bussoloti Filho
Ivo
I
D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013997:Time Factors