Synthesis and characterization of single-phase silicon-substituted alpha-tricalcium phosphate.
Silicon-substituted calcium phosphate (CaP) powders with a Ca/(P+Si) ratio of 1.50 have been prepared by a wet chemical method, with silicon contents up to 2.16 weight percent (wt%). Sintering for 2 h at 1250 degrees C yields single-phase silicon-substituted alpha tricalcium phosphate (Si-alpha-TCP) for compositions between 0.59 and 1.14 wt% silicon. The sintered powders have been characterized with X-ray fluorescence (XRF) spectrometry, X-ray diffraction (XRD), attenuated total reflection infrared spectroscopy (ATR-IR) and transmission electron microscopy (TEM). Compositions with less than 0.59 wt% silicon result in mixtures of Si-alpha-TCP, beta-TCP, and calcium hydroxyapatite (HA), while compositions with more than 1.14 wt% silicon result in mixtures of Si-alpha-TCP and HA. The lattice parameters of single-phase Si-alpha-TCP prepared with 0.87 wt% silicon are a=12.874(1)A, b = 27.372(2) A, c = 15.225(1) A, and beta = 126.38(1) degrees .
Reid
Joel W
JW
Millenium Biologix Corp., 785 Midpark Drive, Kingston, Ont., Canada K7M 7G3. joel.reid@millenium-biologix.com
Tuck
Loughlin
L
Sayer
Michael
M
Fargo
Karen
K
Hendry
Jason A
JA
D018786:Bone Substitutes / Q000032:analysis* / Q000737:chemistry*; D002130:Calcium Phosphates / Q000032:analysis* / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D008422:Materials Testing; D008968:Molecular Conformation; D010316:Particle Size; D044367:Phase Transition; D012825:Silicon / Q000737:chemistry*
D018786:Bone Substitutes; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; D012825:Silicon