title: Retrospective gating for mouse cardiac MRI.
abstract: Cardiac MR imaging in small animals presents some difficulties due to shorter cardiac cycles and smaller dimensions than in human beings, but prospectively gated techniques have been successfully applied. As with human imaging, there may be certain applications in animal imaging for which retrospective gating is preferable to prospective gating. For example, cardiac imaging in multiple mice simultaneously is one such application. In this work we investigate the use of retrospective gating for cardiac imaging in a mouse. Using a three-dimensional imaging protocol, we show that image quality with retrospective gating is comparable to prospectively gated imaging. We conclude that retrospective gating is applicable for small animal cardiac MRI and show how it can be applied to the problem of cardiac MRI in multiple mice.
authors.affiliation: Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Bishop
authors.forename: Akiva
authors.initials: A
authors.lastname: Feintuch
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Bock
authors.forename: Brian
authors.initials: B
authors.lastname: Nieman
authors.forename: Jun
authors.initials: J
authors.lastname: Dazai
authors.forename: Lorinda
authors.initials: L
authors.lastname: Davidson
authors.forename: R Mark
authors.initials: RM
authors.lastname: Henkelman
mesh_terms: D000818:Animals; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D051379:Mice