title: Polygalacturonase-inhibiting protein (PGIP) in plant defence: a structural view.
abstract: Polygalacturonase-inhibiting proteins are plant extracellular leucine-rich repeat proteins that specifically bind and inhibit fungal polygalacturonases. The interaction with PGIP limits the destructive potential of polygalacturonases and might trigger the plant defence responses induced by oligogalacturonides. A high degree of polymorphism is found both in PGs and PGIPs, accounting for the specificity of different plant inhibitors for PGs from different fungi. Here, we review the structural features and our current understanding of the PG-PGIP interaction.
authors.affiliation: Dipartimento di Biologia Vegetale, Universita' di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.
authors.forename: Adele
authors.initials: A
authors.lastname: Di Matteo
authors.forename: Daniele
authors.initials: D
authors.lastname: Bonivento
authors.forename: Demetrius
authors.initials: D
authors.lastname: Tsernoglou
authors.forename: Luca
authors.initials: L
authors.lastname: Federici
authors.forename: Felice
authors.initials: F
authors.lastname: Cervone
mesh_terms: D000818:Animals; D006801:Humans; D007930:Leucine / Q000737:chemistry; D008958:Models, Molecular; D010940:Plant Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D011096:Polygalacturonase / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: C081479:PGIP protein, plant; D010940:Plant Proteins; D011096:Polygalacturonase; D007930:Leucine