title: Factors affecting the quality of life in childhood epilepsy in China.
abstract: OBJECTIVE
  To explore the level of, and factors affecting the quality of life (QOL) in childhood epilepsy in China.
  
  
  METHODS
  At the Peking University First Hospital, we consecutively identified 418 parents whose children were with known epilepsy to complete a questionnaire, which included children's demographic characteristics, clinical message of epilepsy, QOL, familial message, parental symptoms of anxiety/depression.
  
  
  RESULTS
  Significant (p<0.05) affecting factors of children's quality of life included current educational degree, mental development, age at diagnosis, age at onset, seizure frequency, duration, AED number; parental significant (p<0.05) affecting factors included anxiety, depression and health. On regression analysis, parental anxiety was the most important factor in explaining lower QOL in childhood epilepsy. AEDs, familial economic state, paternal career, seizure frequency were also significant factors.
  
  
  CONCLUSIONS
  Parental anxiety outweighed the physical factors in determining QOL in childhood epilepsy. Recognition of this will be helpful for professionals to treat disease and improve the QOL of childhood epilepsy.
authors.affiliation: Institute of Child and Adolescent Health, Peking University, Beijing, China.
authors.forename: L
authors.initials: L
authors.lastname: Yong
authors.forename: J
authors.initials: J
authors.lastname: Chengye
authors.forename: Q
authors.initials: Q
authors.lastname: Jiong
mesh_terms: D017668:Age of Onset; D001007:Anxiety; D002648:Child; D002675:Child, Preschool; D002681:China / Q000208:ethnology; D003430:Cross-Sectional Studies; D004522:Educational Status; D004827:Epilepsy / Q000150:complications / Q000208:ethnology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D010287:Parent-Child Relations; D011788:Quality of Life; D012720:Severity of Illness Index