title: Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device.
abstract: Thirty-seven consecutive patients with elevated PSA levels and negative tumor prostate biopsies underwent a MR-guided prostate biopsy in a 1.5-T scanner in the supine position. After localization of suspected tumor areas using an endorectal coil and two body-phased array coils, the biopsy device was positioned without any repositioning of the patient. The biopsy device consisted of a mount, a ball joint, a positioning stage and an insertion stage with a needle guide, which was filled with a MR-visible fluid to control positioning of the needle using a balanced steady-state free precession sequence (TrueFISP) and a high-resolution turbo spin echo (T2-TSE) sequence. Core biopsies were taken manually in the magnet. The biopsy needle could be correctly positioned in all cases. Suspected lesions with a diameter > or =10 mm could be successfully punctured. Four to nine (mean = 6) biopsies were taken per patient. In 14 patients, prostate cancer was confirmed at histology. Twenty-four biopsies positive for cancer were performed in 14 patients. A correct correlation was found between the site of biopsy and histology. MR-guided prostate biopsy can be effective in increasing primary positive tumor biopsy results in patients with a history of negative tumor TRUS-guided prostate biopsies.
authors.affiliation: Radiologische Abteilung, Krankenhaus Martha-Maria, Stadenstr. 59, 90491 Nürnberg, Germany. k.engelhard@martha-maria.de
authors.forename: K
authors.initials: K
authors.lastname: Engelhard
authors.forename: H P
authors.initials: HP
authors.lastname: Hollenbach
authors.forename: B
authors.initials: B
authors.lastname: Kiefer
authors.forename: A
authors.initials: A
authors.lastname: Winkel
authors.forename: K
authors.initials: K
authors.lastname: Goeb
authors.forename: D
authors.initials: D
authors.lastname: Engehausen
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D003287:Contrast Media; D004867:Equipment Design; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000032:analysis; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology; D011472:Prostatitis / Q000473:pathology; D015642:Radiology, Interventional / Q000379:methods*; D016683:Supine Position
chemical_list: D003287:Contrast Media; D017430:Prostate-Specific Antigen