title: Effect of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.
abstract: OBJECTIVE
  To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.
  
  
  METHODS
  The levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole.
  
  
  RESULTS
  After one course of treatment with liniment levamisole, the levels of CD3(+), CD4(+), and the ratio of CD4(+)/CD8(+) increased as compared to those before the treatment but the level of CD8(+) decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole.
  
  
  CONCLUSIONS
  Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.
authors.affiliation: Department of Pathogenic Biology, School of Medicine, Anhui University of Science and Technology, Huainan 232001, Anhui Province, China. cpli@aust.edu.cn
authors.forename: Ke-Xia
authors.initials: KX
authors.lastname: Wang
authors.forename: Li-Hua
authors.initials: LH
authors.lastname: Zhang
authors.forename: Jiang-Long
authors.initials: JL
authors.lastname: Peng
authors.forename: Yong
authors.initials: Y
authors.lastname: Liang
authors.forename: Xue-Feng
authors.initials: XF
authors.lastname: Wang
authors.forename: Hui
authors.initials: H
authors.lastname: Zhi
authors.forename: Xiang-Xia
authors.initials: XX
authors.lastname: Wang
authors.forename: Huan-Xiong
authors.initials: HX
authors.lastname: Geng
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000328:Adult; D005260:Female; D019694:Hepatitis B, Chronic / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007978:Levamisole / Q000008:administration & dosage*; D008038:Liniments; D008297:Male; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000187:drug effects / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D008038:Liniments; D007978:Levamisole