title: Pattern of positions sensitive to mutations in human haemoglobin alpha-chain.
abstract: In this study, we used the distribution rank, which has been developed by us over the past several years, to quantify 134 mutations in the human hemoglobin alpha-chain in order to gain an insight into the general pattern in mutations. The results suggest that the pattern presented by distribution rank can approximately estimate the positions that are sensitive to mutations in human hemoglobin alpha-chain.
authors.affiliation: Department of Pharmacology, Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Nannan
authors.initials: N
authors.lastname: Gao
authors.forename: Shaomin
authors.initials: S
authors.lastname: Yan
authors.forename: Guang
authors.initials: G
authors.lastname: Wu
mesh_terms: D006454:Hemoglobins / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D009154:Mutation; D011336:Probability
chemical_list: D006454:Hemoglobins