title: [An experience of intra-arterial thrombolytic therapy of ischemic stroke in Uzbek republic center of emergency care].
abstract: Acute period of stroke is a crucial stage of the disease. The differential therapy in the first 3-6 h from the onset of acute ischemic stroke, so-called "therapeutic window", is of special importance. Obviously, favorable clinical outcome in such patients is largely depends on the early recanalization during "therapeutic window". Presented, are the results of intra-arterial thrombolysis in patients with ischemic stroke, which reveal its high therapeutic effectiveness. Though there was limited clinical evidence for a high effect of recanalization of intra-arterial thrombolysis, this approach opens new perspectives for large scale clinical investigations using endovascular methods in thrombolytic therapy of patients with ischemic stroke.
authors.forename: B G
authors.initials: BG
authors.lastname: Gafurov
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Zakhidov
mesh_terms: D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004636:Emergency Service, Hospital; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy / Q000379:methods*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D017585:Ultrasonography, Doppler, Transcranial; D014610:Uzbekistan
chemical_list: D005343:Fibrinolytic Agents