Restoration of accommodation.
OBJECTIVE
This review examines the current status of accommodation restoration concepts with reference to the recent, published peer-reviewed literature with an emphasis on physiological aspects of accommodation and presbyopia.


RESULTS
The mechanisms of accommodation and the causes of presbyopia are described. The physiological amenability of the accommodative structures in the presbyopic eye to accommodation restoration is discussed. General theoretical concepts of accommodation restoration are introduced. The methods that have been used to assess accommodation restoration, including the use of animal models, drug stimulated accommodation, subjective near-vision tests and objective measurements, are reviewed.


CONCLUSIONS
While physiological and clinical evidence supports the notion that accommodation can be restored to the presbyopic eye, progress in this potentially exciting area is hindered by the scarcity of good, large-scale clinical studies using objective measurement techniques to evaluate the outcomes of accommodation restoration concepts.
Glasser
Adrian
A
College of Optometry, 4901 Calhoun Rd, University of Houston, TX 77204-2020, USA. aglasser@uh.edu
D000065:Accommodation, Ocular / Q000502:physiology*; D006801:Humans; D019654:Lens Implantation, Intraocular; D011305:Presbyopia / Q000503:physiopathology; D015626:Tissue Expansion / Q000379:methods