title: Eosinophilic cystitis: successful long-term treatment with montelukast sodium.
abstract: We report a rare case of eosinophilic cystitis in a 6-year-old boy who presented with irritative voiding symptoms, peripheral eosinophilia, and a bladder mass initially visualized on ultrasonography. Cystoscopy and transurethral biopsy confirmed the diagnosis. Complete resolution of his symptoms occurred within 1 week of corticosteroid use and the x-ray findings improved within 6 weeks. At 6 months of follow-up, the patient continued to require a leukotriene receptor antagonist (montelukast sodium) despite several attempts to discontinue its use. We propose that eosinophilic cystitis in children who present with peripheral eosinophilia will often require long-term treatment.
authors.affiliation: Department of Urology, University of Nebraska Medical Center, Omaha, Nebraska 68198-2360, USA. ssterrett@unmc.edu
authors.forename: S
authors.initials: S
authors.lastname: Sterrett
authors.forename: J
authors.initials: J
authors.lastname: Morton
authors.forename: D
authors.initials: D
authors.lastname: Perry
authors.forename: J
authors.initials: J
authors.lastname: Donovan
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D002648:Child; D003521:Cyclopropanes; D003556:Cystitis / Q000150:complications / Q000188:drug therapy*; D004802:Eosinophilia / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use*; D008297:Male; D011804:Quinolines / Q000627:therapeutic use*; D012074:Remission Induction; D013440:Sulfides; D013997:Time Factors
chemical_list: D000085:Acetates; D003521:Cyclopropanes; D020024:Leukotriene Antagonists; D011804:Quinolines; D013440:Sulfides; C093875:montelukast