title: A practical and green approach towards synthesis of dihydropyrimidinones: using heteropoly acids as efficient catalysts.
abstract: A simple and green chemistry procedure for the synthesis of dihydropyrimidinones using heteropoly acid mediated cyclocondensation reaction is described. This method provides an efficient and much improved modification of the original Biginelli reaction reported in 1893, in terms of high yields, and short reaction times. It has the ability to allow a wide variety of substitutions in all three components.
authors.affiliation: Department of Chemistry, Faculty of Science, Razi University, Kermanshah 67149, Iran. e.rafiei@razi.ac.ir
authors.forename: Ezzat
authors.initials: E
authors.lastname: Rafiee
authors.forename: Hadi
authors.initials: H
authors.lastname: Jafari
mesh_terms: D000143:Acids / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000143:Acids; D011744:Pyrimidinones