Serial cholinesterase estimation in carbamate poisoning.
Poisoning is one of the most important causes of morbidity and mortality in developing countries like India. Anticholinesterase compounds like organophosphates (OP) and carbamates account for the majority of these poisoning cases because of their easy availability and agricultural use. Carbamates are as popular as OPs as insecticides that often go undiagnosed. A fatal case of carbofuran poisoning is presented where serial cholinesterase estimation played a major role in the diagnosis of the same. The pertinent medical literature on carbofuran poisoning is reviewed. The establishment of poison information center in each state is needed for proper diagnosis and management of poisoning cases.
Pinakini
K S
KS
Pharmacology, Melaka Manipal Medical College, Manipal 576104, India. pimochi@yahoo.co.in
Kumar
T S Mohan
TS
D002235:Carbofuran / Q000506:poisoning*; D002800:Cholinesterase Inhibitors / Q000506:poisoning*; D002801:Cholinesterase Reactivators / Q000627:therapeutic use; D002802:Cholinesterases / Q000097:blood*; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D011220:Pralidoxime Compounds / Q000627:therapeutic use
D002800:Cholinesterase Inhibitors; D002801:Cholinesterase Reactivators; D011220:Pralidoxime Compounds; D002802:Cholinesterases; C028797:pralidoxime; D002235:Carbofuran