title: Orbital metastasis from breast carcinoma presenting as neurotrophic keratitis.
abstract: METHODS
  This is a case report of an 81-year-old woman with previous breast cancer. The patient presented with a history of unilateral painless red eye and displayed on examination a nodule in the superior orbital rim, proptosis, and neurotrophic keratitis. Clinical and radiographic examinations were followed by biopsy of the orbital mass. Computed tomography displayed an extraconal mass adjacent to the left superior orbital rim extending to the soft tissues. Light microscopy findings suggested the diagnosis of orbital metastatic breast carcinoma that was confirmed by immunohistochemistry. The histopathologic diagnosis was metastatic adenocarcinoma of the breast to the left orbit.
  
  
  CONCLUSIONS
  This study emphasizes that orbital metastasis must be considered in patients with ocular complaints and neoplastic disease thought to be stable.
authors.affiliation: Department of Ophthalmology, McGill University Health Centre, Montreal, Que. hpsolari@yahoo.com.br
authors.forename: Helena Parente
authors.initials: HP
authors.lastname: Solari
authors.forename: Marcelo Palis
authors.initials: MP
authors.lastname: Ventura
authors.forename: Devinder P
authors.initials: DP
authors.lastname: Cheema
authors.forename: Alexandre Nakao
authors.initials: AN
authors.lastname: Odashiro
authors.forename: Miguel N
authors.initials: MN
authors.lastname: Burnier
mesh_terms: D000369:Aged, 80 and over; D001706:Biopsy; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D014057:Tomography, X-Ray Computed