title: Neoadjuvant radiochemotherapy for patients with locally advanced rectal cancer leads to impairment of the anal sphincter.
authors.affiliation: Department of Surgery, Klinikum Rechts der Isar, Technische Universität Muenchen, Ismaningerstrasse 22, 81675 Munich, Germany. theisen@nt1.chir.med.tu-muenchen.de
authors.forename: Joerg
authors.initials: J
authors.lastname: Theisen
authors.forename: Werner K-H
authors.initials: WK
authors.lastname: Kauer
authors.forename: Hjalmar
authors.initials: H
authors.lastname: Nekarda
authors.forename: Ludwig
authors.initials: L
authors.lastname: Schmid
authors.forename: Hubert J
authors.initials: HJ
authors.lastname: Stein
authors.forename: Joerg-Ruediger
authors.initials: JR
authors.lastname: Siewert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal / Q000187:drug effects / Q000503:physiopathology* / Q000528:radiation effects; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D020360:Neoadjuvant Therapy; D011312:Pressure; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D005472:Fluorouracil