Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid-base status.
OBJECTIVE
We evaluated the effect of two different preload solutions: (i) Ringer's lactate (compound sodium lactate intravenous infusion BP) and (ii) 0.9% sodium chloride solution on the neonatal acid-base status of the newborn infants. The two standard regimens were compared to detect a possible difference.


METHODS
A 2 L crystalloid fluid bolus was administered immediately before spinal anaesthesia for elective Caesarean section in two groups of 20 healthy parturients, while rigorously maintaining maternal normotension.


RESULTS
No significant differences in the Apgar scores at 1 and 5 min, or infant well-being were demonstrated in either of the two groups. The data show that umbilical artery PCO2 is lower in the Ringer's lactate group and that pH is insignificantly higher by 0.03.


CONCLUSIONS
The choice of Ringer's lactate or saline for fluid preload does not have any effect on neonatal well-being.
Chanimov
M
M
Assaf Harofeh Medical Center, Department of Anesthesiology, Zerifin, Israel.
Gershfeld
S
S
Cohen
M L
ML
Sherman
D
D
Bahar
M
M
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D002585:Cesarean Section; D000077324:Crystalloid Solutions; D004311:Double-Blind Method; D004809:Ephedrine / Q000008:administration & dosage; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007022:Hypotension / Q000188:drug therapy; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D007552:Isotonic Solutions / Q000008:administration & dosage*; D011247:Pregnancy; D011446:Prospective Studies; D000077325:Ringer's Lactate; D012965:Sodium Chloride / Q000008:administration & dosage; D016896:Treatment Outcome; D014662:Vasoconstrictor Agents / Q000008:administration & dosage
D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D000077325:Ringer's Lactate; D014662:Vasoconstrictor Agents; D012965:Sodium Chloride; D004809:Ephedrine