Steroid and/or other immunosuppressive therapies in idiopathic interstitial pneumonias: have they still a role?
The idiopathic interstitial pneumonias (IIPs) comprise a number of clinico-pathological entities of unknown origin, which are sufficiently different from one another to be designated as separate disease entities. The aim of this review is to describe the level of evidence available on the efficacy of corticosteroids and immunosuppressive, antifibrotic, or immunomodulatory therapies in the treatment of different IIPs.
Luppi
Fabrizio
F
Clinic of Respiratory Disease, Department of Oncology and Hematology, University of Modena and Reggio Emilia, Modena, Italy.
Cerri
Stefania
S
Richeldi
Luca
L
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D001989:Bronchiolitis Obliterans / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality; D008297:Male; D011379:Prognosis; D011658:Pulmonary Fibrosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012720:Severity of Illness Index; D015996:Survival Rate; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents