A new method for the synthesis of Z-enediones via IBX-mediated oxidative rearrangement of 2-alkynyl alcohol systems.
o-Iodoxybenzoic acid (IBX) was found to mediate the conversion of alpha-alkynyl alcohols into Z-enediones under notably mild conditions via a novel rearrangement mechanism (33-65% yield, 13 examples).
Crone
Benedikt
B
Department Chemie, Technische Universität München, Lichtenbergstr. 4, 85747, Garching, Germany.
Kirsch
Stefan F
SF