title: Vestibular schwannoma management: What is the 'best' option?
abstract: There is an abundance of medical literature describing the management options for vestibular schwannomas. However, the lack of high quality clinical trials means that, for any individual patient, the decision is often based on the clinician's personal biases. The management options that are available are conservative treatment, surgery, single-dose stereotactic radiosurgery and fractionated radiotherapy. In this review, we set out what the aims of managing a vestibular schwannoma should be and compare how these different treatment modalities perform. The particular objectives of tumour control, cranial nerve preservation, prevention of malignancy, quality of life and cost-effectiveness are discussed. It remains difficult to differentiate between these methods when more than one is suitable; the literature confirms that they are all safe and effective, but the decision must be the patient's, based on their individual priorities. This review should equip the clinician to provide an informed overview of the options.
authors.affiliation: Department of Neurosurgery, Hope Hospital, Manchester, UK. scott.rutherford@srht.nhs.uk
authors.forename: S A
authors.initials: SA
authors.lastname: Rutherford
authors.forename: A T
authors.initials: AT
authors.lastname: King
mesh_terms: D003362:Cost-Benefit Analysis; D018450:Disease Progression; D005158:Facial Paralysis / Q000517:prevention & control; D006311:Hearing Disorders / Q000517:prevention & control; D006801:Humans; D009464:Neuroma, Acoustic / Q000150:complications / Q000191:economics / Q000628:therapy*; D011183:Postoperative Complications / Q000517:prevention & control; D011788:Quality of Life