title: Rotaxanes of cyclic peptides.
abstract: The synthesis of rotaxanes derived from the synthetic peptide macrocycles cyclo(l-ProGly)4 and cyclo(l-ProGly)5 and diammonium threads is described. [2]Rotaxanes are formed in good yields (56-63%), despite the disruption of internal amide-amide hydrogen bonding in the macrocycles.
authors.affiliation: University of Edinburgh, School of Chemistry, The King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK.
authors.forename: Vincent
authors.initials: V
authors.lastname: Aucagne
authors.forename: David A
authors.initials: DA
authors.lastname: Leigh
authors.forename: Julia S
authors.initials: JS
authors.lastname: Lock
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Thomson
mesh_terms: D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D043862:Rotaxanes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D010456:Peptides, Cyclic; D043862:Rotaxanes; C062238:cyclo(prolylglycyl)