Polygalacturonase-inhibiting protein (PGIP) in plant defence: a structural view.
Polygalacturonase-inhibiting proteins are plant extracellular leucine-rich repeat proteins that specifically bind and inhibit fungal polygalacturonases. The interaction with PGIP limits the destructive potential of polygalacturonases and might trigger the plant defence responses induced by oligogalacturonides. A high degree of polymorphism is found both in PGs and PGIPs, accounting for the specificity of different plant inhibitors for PGs from different fungi. Here, we review the structural features and our current understanding of the PG-PGIP interaction.
Di Matteo
Adele
A
Dipartimento di Biologia Vegetale, Universita' di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.
Bonivento
Daniele
D
Tsernoglou
Demetrius
D
Federici
Luca
L
Cervone
Felice
F
D000818:Animals; D006801:Humans; D007930:Leucine / Q000737:chemistry; D008958:Models, Molecular; D010940:Plant Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D011096:Polygalacturonase / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation
C081479:PGIP protein, plant; D010940:Plant Proteins; D011096:Polygalacturonase; D007930:Leucine