title: Developing a physical model of the human cochlea using micro-fabrication methods.
abstract: Advances in micro-machining technology have provided the opportunity to explore possibilities of creating life-sized physical models of the cochlea. The physical model of the cochlea consists of two fluid-filled channels separated by an elastic partition. The partition is micro-machined from silicon and uses a 36-mm linearly tapered polyimide plate with a width of 100 microm at the basal end and 500 microm at the apex to represent the basilar membrane. Thicknesses from 1 to 5 microm have been fabricated. Discrete aluminum fibers (1.5 microm in width) are machined to create direction-dependent properties. A 0.5 x 0.5 mm opening represents the helicotrema. The fluid channels are machined from plexiglas using conventional machining methods. A magnet-coil system excites the fluid channel. Measurements on a model with thickness 4.75 microm show a velocity gain of 4 and phase of 3.5 pi radians at a location 23 mm from the base. Mathematical modeling using a 3-D formulation confirm the general characteristics of the measured response.
authors.affiliation: Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Wittbrodt
authors.forename: Charles R
authors.initials: CR
authors.lastname: Steele
authors.forename: Sunil
authors.initials: S
authors.lastname: Puria
mesh_terms: D001307:Auditory Perception / Q000502:physiology; D001489:Basilar Membrane / Q000033:anatomy & histology / Q000502:physiology; D003051:Cochlea / Q000033:anatomy & histology* / Q000502:physiology*; D003198:Computer Simulation; D004582:Electronics, Medical / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008432:Mathematical Computing; D008953:Models, Anatomic; D008954:Models, Biological; D009925:Organ of Corti / Q000033:anatomy & histology / Q000502:physiology; D013199:Stapes / Q000033:anatomy & histology / Q000502:physiology; D014159:Transducers