title: Bacteriuria, pyuria and bacteremia frequency following outpatient cystoscopy.
abstract: OBJECTIVE
  The assumed necessity of antimicrobial prophylaxis prior to cystoscopy is controversial. In this study, the rate of bacteriuria, pyuria and bacteremia in outpatients who underwent cystoscopy without antimicrobial prophylaxis is investigated prospectively.
  
  
  METHODS
  The study included 75 patients who underwent cystoscopy for various indications and had sterile urine prior to intervention. A clean midstream urine sample was obtained 24 h before and 48 h after the procedure. Blood cultures were taken 1 h after cystoscopy. Patients were questioned for newly developed symptoms 48 h after cystoscopy. Blood cultures were taken again from patients who presented with fever.
  
  
  RESULTS
  Six patients (8%) developed significant bacteriuria, and six patients (8%) developed pyuria without significant bacteriuria. Bacteremia was not determined in any of the patients. The association between presence of pyuria prior to the procedure and development of bacteriuria after the procedure was significant (P < 0.05). Four patients out of six who had bacteriuria were asymptomatic. In our study we found significant bacteriuria after cystoscopy in 8% of patients, and no bacteremia.
  
  
  CONCLUSIONS
  Thus we conclude that cystoscopy is a safe and well-tolerated procedure. Antimicrobial prophylaxis should not be administrated unless specific indications are present.
authors.affiliation: Ankara Training and Research Hospital Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey. turanhale@yahoo.com
authors.forename: Hale
authors.initials: H
authors.lastname: Turan
authors.forename: Ugur
authors.initials: U
authors.lastname: Balci
authors.forename: F Sebnem
authors.initials: FS
authors.lastname: Erdinc
authors.forename: Necla
authors.initials: N
authors.lastname: Tulek
authors.forename: Cankon
authors.initials: C
authors.lastname: Germiyanoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures / Q000009:adverse effects*; D016470:Bacteremia / Q000453:epidemiology* / Q000209:etiology; D001437:Bacteriuria / Q000453:epidemiology* / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003558:Cystoscopy / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011776:Pyuria / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors