Molecular-level control of feature separation in one-dimensional nanostructure assemblies formed by biomolecular nanolithography.
In this paper, we present a convenient and reliable method to organize small gold nanoparticles (d(CORE) = 1.5 nm) into linear chains with precisely controlled interparticle spacing over a range of 1.5-2.8 nm through biomolecular nanolithography. Controlling the feature separations of 1 to a few nanometers with angstrom-level precision is a key requirement in electronic and optical applications of nanostructures to tune the properties of the nanostructures and manipulate the interactions between neighboring structures. Here, chains are formed in solution by utilizing functional-group-directed self-assembly to organize ligand-stabilized gold nanoparticles onto DNA templates. The spacing between neighboring nanoparticles can be controlled chemically and tuned at the molecular level by utilizing nanoparticles possessing ligand shells of varying thickness to achieve angstrom-level resolution at spacings of 1.5, 2.1, and 2.8 nm. The small standard deviation (< or = 20%) in the values for the interparticle spacing illustrates the reproducibility of the approach. Because the interparticle spacing is enforced by the ligand shell rather than the scaffold, the spacing is uniform even in nonlinear sections of the chain. We further show that the assembly process is robust and produces extended linear nanoparticle chains of up to 1 microm in length and a total coverage of > 90%. All structures and interparticle spacings were analyzed using transmission electron microscopy. Our results demonstrate the potential of scaffold-assisted assembly approaches for patterning features with tunable dimensions on a length scale that is important for future applications of these materials in nanoscale electronics and optics.
Woehrle
Gerd H
GH
Department of Chemistry and Materials Science Institute, 1253 University of Oregon, Eugene, Oregon 97403, USA.
Warner
Marvin G
MG
Hutchison
James E
JE
D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D008024:Ligands; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D013329:Structure-Activity Relationship; D013499:Surface Properties
D008024:Ligands; D006046:Gold; D004247:DNA