title: Diagnosis of placental abscess in association with recurrent maternal bacteremia in a twin pregnancy.
abstract: BACKGROUND
  Placental abscess formation is rarely recognized prenatally. We present a case detected ultrasonographically that developed from a central line infection and caused recurrent maternal bacteremia.
  
  
  METHODS
  A young woman with a 21-week twin gestation presented with recurrent fevers. She had received treatment for bacteremia due to Serratia marcescens. The initial source of the infection was a peripherally inserted central catheter line placed in the first trimester for hyperemesis gravidarum. Fevers continued throughout the second course of antibiotics. An abscess seen sonographically in twin A's placenta was aspirated using a spinal needle, revealing Serratia bacteria. Aspiration was performed at 22 weeks of gestation. Amniotic fluid samples obtained from both sacs were negative for infection. Over 4 weeks, the abscess enlarged and she was delivered. Twin A died of sepsis and twin B had a relatively favorable neonatal course.
  
  
  CONCLUSIONS
  Prenatal diagnosis of placental abscess presents a difficult management dilemma. Traditional amniotic fluid studies did not predict the poor outcome of the affected fetus.
authors.affiliation: Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA. nmeirowitz@pol.net
authors.forename: Natalie B
authors.initials: NB
authors.lastname: Meirowitz
authors.forename: Adiel
authors.initials: A
authors.lastname: Fleischer
authors.forename: Michele
authors.initials: M
authors.lastname: Powers
authors.forename: Francine
authors.initials: F
authors.lastname: Hippolyte
mesh_terms: D000038:Abscess / Q000150:complications / Q000000981:diagnostic imaging*; D000328:Adult; D016470:Bacteremia / Q000209:etiology*; D005260:Female; D006801:Humans; D010922:Placenta Diseases / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000000981:diagnostic imaging*; D011272:Pregnancy, Multiple; D012008:Recurrence; D016868:Serratia Infections / Q000150:complications / Q000000981:diagnostic imaging*; D012706:Serratia marcescens; D016216:Ultrasonography, Prenatal