title: Double-headed acyclo C-nucleoside analogues. Functionalized 1,2-bis-(1,2,4-triazol-3-yl)ethane-1,2-diol.
abstract: Reaction of L-tartaric acid with thiocarbohydcrazide afforded (1R, 2S)-1,2-bis(4-amino-5-mercapto-1,2,4-triazol-3-yl)-ethane-1,2-diol (3). The functional groups in 3 allowed the construction of fused heterocycles on the 1,2,4-triazole rings, mainly of the 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine type as in 4, 5, 7, 10, 13 and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole type as in 14.
authors.affiliation: Chemistry Department, faculty of Science, Zagazig University, Zagazig.
authors.forename: A H
authors.initials: AH
authors.lastname: Moustafa
authors.forename: R A
authors.initials: RA
authors.lastname: Haggam
authors.forename: M E
authors.initials: ME
authors.lastname: Younes
authors.forename: E S H
authors.initials: ES
authors.lastname: El Ashry
mesh_terms: D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D009705:Nucleosides; D014230:Triazoles