The use of desorption/ionization on porous silicon mass spectrometry for the detection of negative ions for fatty acids.
The study of low molecular weight compounds by matrix-assisted laser desorption/ionization (MALDI) is difficult because of the presence of ions originating from the matrix in the low-m/z range. In order to resolve these problems, new matrix-free approaches were developed based on laser desorption/ionization from the surface of various materials such as graphite and porous silicon. Our work involves the use of 'desorption ionization on porous silicon mass spectrometry' (DIOS-MS) in the negative ion mode to study fatty acid compounds. The potential of the DIOS-MS technique is shown and an insight into the ionization mechanism provided.
Budimir
Natali
N
Equipe de Spectrométrie de masse (LCSOB) UMR 7613 CNRS (Synthèse, Structure et Fonction de Molécules Bioactives), B45, Université Pierre et Marie Curie, 4 place Jussieu, 75252 Paris Cedex 05, France.
Blais
Jean-Claude
JC
Fournier
Françoise
F
Tabet
Jean-Claude
JC
D000838:Anions / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry*; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D012825:Silicon / Q000737:chemistry*
D000838:Anions; D005227:Fatty Acids; D011108:Polymers; D012825:Silicon