title: Bisphosphonate-related osteonecrosis of the jaws.
abstract: The purpose of this paper is to highlight an emerging phenomenon of osteonecrosis of the jaws that occurs in some patients who are on long-term bisphosphonate therapy. The condition can appear spontaneously or as a result of trauma, and is difficult to treat. Dental surgeons must be aware of patients who are at risk and institute appropriate preventive care. It is also important to recognize the condition when it does appear and refer appropriately. We present the first local case series of the condition showing varied clinical presentations and treatments.
authors.affiliation: Department of Oral and Maxillofacial Surgery, National Dental Centre, Singapore. a-yeo@rocketmail.com
authors.forename: Aidan Choon-Poh
authors.initials: AC
authors.lastname: Yeo
authors.forename: Kok-Weng
authors.initials: KW
authors.lastname: Lye
authors.forename: Choy-Yoke
authors.initials: CY
authors.lastname: Poon
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000139:chemically induced / Q000628:therapy; D008439:Maxillary Diseases / Q000139:chemically induced / Q000628:therapy; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced* / Q000628:therapy; D014081:Tooth Extraction / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents; D050071:Bone Density Conservation Agents; D004164:Diphosphonates