title: [OPUS: a randomised multicenter trial of integrated versus standard treatment for patients with a first-episode psychosis--secondary publication].
abstract: A total of 547 patients with first-episode psychosis were included in a randomised clinical trial comparing integrated treatment with standard treatment. The integrated treatment consisted of assertive community treatment with programmes for family involvement and social skills training. Patients in integrated treatment had significantly fewer psychotic and negative symptoms, less comorbid substance abuse, better adherence to treatment and more satisfaction with treatment at one-year and two-year follow-ups.
authors.affiliation: H:S Bispebjerg Hospital, Psykiatrisk Afdeling, København NV. merete.nordentoft@dadlnet.dk
authors.forename: Merete
authors.initials: M
authors.lastname: Nordentoft
authors.forename: Lone
authors.initials: L
authors.lastname: Petersen
authors.forename: Pia
authors.initials: P
authors.lastname: Jeppesen
authors.forename: Anne A Elgaard
authors.initials: AA
authors.lastname: Thorup
authors.forename: Maj-Britt Helle
authors.initials: MB
authors.lastname: Abel
authors.forename: Johan
authors.initials: J
authors.lastname: Ohlenschlaeger
authors.forename: Torben Østergaard
authors.initials: TØ
authors.lastname: Christensen
authors.forename: Gertrud
authors.initials: G
authors.lastname: Krarup
authors.forename: Per
authors.initials: P
authors.lastname: Jørgensen
mesh_terms: D000293:Adolescent; D000328:Adult; D003156:Community Mental Health Services; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000628:therapy*; D012559:Schizophrenia / Q000628:therapy*; D012944:Social Support; D016896:Treatment Outcome