[The phenotropil treatment of the consequences of brain organic lesions].
Ninety-nine patients with encephalopathy developed in the remote period after acute lesions of cerebral blood circulation, brain traumas and cerebral gliomas surgery have been studied. Phenotropil was used in a dosage of 200 mg per day during one month. A CT survey revealed that in a stable state of brain changes phenotropil exerted the mostly pronounced influence on movement disturbances: decreased an extent of pareses in limb and face muscles, improved motor coordination, higher brain functions, memory, attention, counting. Patients exhibited higher mobility and daily activity, along with lower discomfort, anxiety and depression. EEG study showed more intensive alpha- and beta-rhythms, a decrease of paroxysmal activity and slow waves as well as a general tendency to its normalization.
Savchenko
A Iu
AIu
Zakharova
N S
NS
Stepanov
I N
IN
D000328:Adult; D001783:Blood Flow Velocity / Q000187:drug effects; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000502:physiology; D003071:Cognition / Q000187:drug effects; D004569:Electroencephalography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018697:Nootropic Agents / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology
D018697:Nootropic Agents