title: The role of SPECT/CT with 99mTc-MDP image fusion to diagnose temporomandibular dysfunction.
abstract: OBJECTIVE
  The objective of this study was the evaluation of Single Photon Emission Computed Tomography with Technetium 99m Methylene Diphosphonate (SPECT with 99mTc-MDP) and computed tomography (CT), simultaneously acquired image in diagnosis of temporomandibular joint (TMJ) dysfunction.
  
  
  METHODS
  A prospective study was conducted with 33 patients, 29 female and 4 male, all of then presenting signs and/or complaints suggestive of temporomandibular dysfunction. SPECT/CT with 99mTc-MDP was performed in all patients and imaging results compared with final diagnosis and clinical outcome.
  
  
  RESULTS
  The correlation of signs and symptoms with SPECT/CT imaging showed sensitivity 100%, specificity 90.91%, and accuracy 96.97%.
  
  
  CONCLUSIONS
  SPECT/CT with 99mTc-MDP coregistered imaging fusion is a suitable method of temporomandibular dysfunction diagnosis, due to the sensitivity, specificity, and accuracy observed.
authors.affiliation: Oral Radiology Division, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil. alecoutinho@terra.com.br
authors.forename: Alessandra
authors.initials: A
authors.lastname: Coutinho
authors.forename: Marlene
authors.initials: M
authors.lastname: Fenyo-Pereira
authors.forename: Luciano Lauria
authors.initials: LL
authors.lastname: Dib
authors.forename: Eduardo Nóbrega Pereira
authors.initials: EN
authors.lastname: Lima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004164:Diphosphonates; D005157:Facial Pain / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011446:Prospective Studies; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed
chemical_list: D004164:Diphosphonates; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C114890:technetium 99m methylene bisphosphonate