title: Antioxidant in plasma of hemoglobin-E trait.
abstract: A study of antioxidant levels among Thai subjects with a hemoglobin E trait was undertaken. The objective of this study was to determine whether the antioxidant level would be disturbed in the HbE condition. All 185 volunteer subjects, 171 normal healthy subjects and 14 HbE carriers were recruited. For each case, an antioxidant determination was performed using the Trolox equivalent antioxidant capacity (TEAC) method. According to this study, the average antioxidant level in the healthy group was 3.439 +/- 0.220 mM Trolox equivalent, and in HbE trait group was 3.276 +/- 0.209 mM Trolox equivalent. There was a significant decrease of the antioxidant level in the HbE trait group (p = 0.008).
authors.affiliation: Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Attakorn.P@chula.ac.th
authors.forename: Attakorn
authors.initials: A
authors.lastname: Palasuwan
authors.forename: Thanawat
authors.initials: T
authors.lastname: Kittisakulrat
authors.forename: Warisa
authors.initials: W
authors.lastname: Amornrit
authors.forename: Suphan
authors.initials: S
authors.lastname: Soogarun
authors.forename: Viroj
authors.initials: V
authors.lastname: Wiwanitkit
authors.forename: Paweena
authors.initials: P
authors.lastname: Pradniwat
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D001797:Blood Protein Electrophoresis; D016022:Case-Control Studies; D006446:Hemoglobin E / Q000032:analysis*; D006456:Hemoglobinuria / Q000097:blood* / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D018384:Oxidative Stress; D013785:Thailand; D017086:beta-Thalassemia / Q000097:blood* / Q000235:genetics
chemical_list: D000975:Antioxidants; D006446:Hemoglobin E