title: Highly enantioselective synthesis of tetrahydro-beta-carbolines and tetrahydro-gamma-carbolines via Pd-catalyzed intramolecular allylic alkylation.
abstract: A novel Pd-catalyzed intramolecular allylic alkylation of indoles allows THBCs and THGCs to be effectively synthesized in high yields and excellent enantiomeric excesses (ee up to 97%).
authors.affiliation: Dipartimento di Chimica "G. Ciamician", Alma Mater Studiorum, Università di Bologna, via Selmi 2, 40126 Bologna, Italy. marco.bandini@unibo.it
authors.forename: Marco
authors.initials: M
authors.lastname: Bandini
authors.forename: Alfonso
authors.initials: A
authors.lastname: Melloni
authors.forename: Fabio
authors.initials: F
authors.lastname: Piccinelli
authors.forename: Riccardo
authors.initials: R
authors.lastname: Sinisi
authors.forename: Simona
authors.initials: S
authors.lastname: Tommasi
authors.forename: Achille
authors.initials: A
authors.lastname: Umani-Ronchi
mesh_terms: D000478:Alkylation; D000498:Allyl Compounds / Q000737:chemistry*; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000498:Allyl Compounds; D002243:Carbolines; D010165:Palladium; C009804:tryptoline