title: Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.
abstract: Quinoxaline, quinazoline and benzimidazole based templates have been synthesized on solid-support employing different methodologies. This review enlightens academic and industrial examples of combinatorial synthesis for this type of heterocycles that appeared in the literature in the last decade. Hence, some of the important synthetic strategies for the generation of quinoxaline, quinazoline and benzimidazole based privileged structures, and the important biological activities for these heterocycles have been highlighted. Further, benzothiadiazinone, thioxoquinazolinone, cinnoline and indazole are also examined in this review.
authors.affiliation: Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India. ahmedkamal@iict.res.in
authors.forename: Ahmed
authors.initials: A
authors.lastname: Kamal
authors.forename: K Laxma
authors.initials: KL
authors.lastname: Reddy
authors.forename: V
authors.initials: V
authors.lastname: Devaiah
authors.forename: N
authors.initials: N
authors.lastname: Shankaraiah
authors.forename: M V
authors.initials: MV
authors.lastname: Rao
mesh_terms: D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D001581:Benzothiadiazines / Q000138:chemical synthesis; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry; D007191:Indazoles / Q000138:chemical synthesis; D015394:Molecular Structure; D010793:Phthalazines / Q000138:chemical synthesis; D011714:Pyrans / Q000138:chemical synthesis; D011799:Quinazolines / Q000138:chemical synthesis*; D011810:Quinoxalines / Q000138:chemical synthesis*
chemical_list: D001562:Benzimidazoles; D001581:Benzothiadiazines; D006574:Heterocyclic Compounds, 2-Ring; D007191:Indazoles; D010793:Phthalazines; D011714:Pyrans; D011799:Quinazolines; D011810:Quinoxalines; C014353:benzimidazolone; C476282:cinnoline