Dermatomyositis complicated with Kaposi sarcoma: a case report.
We describe the case of a 75-year-old Italian woman affected by dermatomyositis (DM) treated with steroid, high-dose intravenous immunoglobulins (IVIgs) and cyclophosphamide (CPX), taken orally. After a few months, the patient presented multiple red vascular skin lesions diagnosed as Kaposi sarcoma (KS). Steroid was furtherly reduced, and CPX was stopped. We put the patient on chemotherapy with intravenous infusion of vinblastine and vincristine on alternate weeks obtaining the remission of KS. DM is well controlled by a low-dosage steroid and high-dose IVIgs.
Simeoni
Sara
S
Department of Clinical and Experimental Medicine, Section of Internal Medicine, University of Verona, Policlinico GB Rossi, P. le LA Scuro, 37134 Verona, Italy.
Puccetti
Antonio
A
Moruzzi
Sara
S
Tinazzi
Elisa
E
Peterlana
Dimitri
D
Lunardi
Claudio
C
D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D011241:Prednisone / Q000009:adverse effects*; D012514:Sarcoma, Kaposi / Q000139:chemically induced* / Q000188:drug therapy; D014747:Vinblastine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D014750:Vincristine; D014747:Vinblastine; D011241:Prednisone