Serum albumin and self-reported prevalence of stroke: a population-based, cross-sectional study.
BACKGROUND
Since information about the association between serum albumin and risk of stroke is limited the purpose of the present paper was to re-investigate this relationship.


METHODS
The study followed a cross-sectional design.


METHODS
In the cross-sectional Norwegian Oslo Health Study the concentration of serum albumin and blood pressure was determined in a random sample of 5071 men and women, 30-75 years of age. Logistic regression was used to study the association between the serum albumin concentration and self-reported prevalence of stroke. In the sample there were 122 subjects with a history of stroke and 4949 subjects without.


RESULTS
Low albumin (i.e. < or =47 versus >47 g/l) was associated with increased prevalence of self-reported stroke (odds ratio 1.83; 95% confidence interval, 1.20-2.78; P=0.005), after adjusting for age (< or =45 versus > or =59 years) and sex. Including smoking, blood pressure and length of education into the model did not have any major influence on the result.


CONCLUSIONS
Low serum albumin is associated with increased prevalence of self-reported stroke.
Høstmark
Arne T
AT
Department of Preventive Medicine and Epidemiology, University of Oslo, Norway. a.t.hostmark@medisin.uio.no
Tomten
Sissel E
SE
D000328:Adult; D000367:Age Factors; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D012709:Serum Albumin / Q000378:metabolism*; D020521:Stroke / Q000097:blood / Q000453:epidemiology*
D012709:Serum Albumin