title: A case of transient diabetes insipidus following cardiopulmonary bypass.
abstract: Cardiopulmonary bypass surgery has been linked with a number of postoperative complications. One of the frequently reported physiological alterations is the relative diuresis seen in the immediate post-op period. Rarely reported though is the development of full-blown diabetes insipidus in such patients. The etiology is unknown and has only been hypothesized in the past. We present the clinical course of a 54 year old male who developed transient diabetes insipidus post bypass surgery with subsequent recovery following exogenous vasopressin administration. The physiological alteration leading to the development of diabetes insipidus in a small fraction of bypass patients remains unknown. We propose that the variation in natriuretic peptide levels in the post-bypass period could account for the transient event.
authors.affiliation: The Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Omer
authors.initials: O
authors.lastname: Ashraf
authors.forename: Hasanat
authors.initials: H
authors.lastname: Sharif
authors.forename: Mansoor
authors.initials: M
authors.lastname: Shah
mesh_terms: D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D003919:Diabetes Insipidus / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D013997:Time Factors