title: Focus issue: signaling lipids.
abstract: Membranes are dynamic and specific contributors to cell signaling. Cellular membranes play a key structural role in creating sites for the formation of signaling complexes. Changes in membrane phospholipids can regulate the activity of transmembrane and peripheral membrane proteins. Modification of membrane lipids can result in formation of dynamic signaling molecules. Science's STKE highlights new insights into the roles that lipids and membranes play in cell signaling.
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D000818:Animals; D018927:Anti-Asthmatic Agents / Q000494:pharmacology; D001095:Arachidonic Acids / Q000502:physiology; D004281:Docosahexaenoic Acids / Q000378:metabolism; D063388:Endocannabinoids; D005989:Glycerides / Q000502:physiology; D046911:Macromolecular Substances; D008563:Membrane Lipids / Q000502:physiology*; D010718:Phosphatidylserines / Q000502:physiology; D053284:Polyunsaturated Alkamides; D017434:Protein Structure, Tertiary; D018078:Receptors, Prostaglandin E / Q000187:drug effects; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D018927:Anti-Asthmatic Agents; D001095:Arachidonic Acids; D063388:Endocannabinoids; D005989:Glycerides; D046911:Macromolecular Substances; D008563:Membrane Lipids; D010718:Phosphatidylserines; D053284:Polyunsaturated Alkamides; D018078:Receptors, Prostaglandin E; D004281:Docosahexaenoic Acids; C094503:glyceryl 2-arachidonate; C078814:anandamide