Structural-functional model of the mitotic chromosome.
In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.
Polyakov
V Yu
VY
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Zatsepina
O V
OV
Kireev
I I
II
Prusov
A N
AN
Fais
D I
DI
Sheval
E V
EV
Koblyakova
Yu V
YV
Golyshev
S A
SA
Chentsov
Yu S
YS
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002843:Chromatin / Q000737:chemistry / Q000648:ultrastructure; D002868:Chromosomal Proteins, Non-Histone / Q000737:chemistry / Q000378:metabolism; D002875:Chromosomes / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D002877:Chromosomes, Human / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D004247:DNA / Q000737:chemistry; D022041:Euchromatin / Q000737:chemistry / Q000378:metabolism; D006570:Heterochromatin / Q000737:chemistry / Q000378:metabolism; D006657:Histones / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007399:Interphase; D008938:Mitosis
D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D022041:Euchromatin; D006570:Heterochromatin; D006657:Histones; D004247:DNA; D002118:Calcium