title: Anxiety and depression symptoms in psychometrically identified schizotypy.
abstract: The neurodevelopmental vulnerability for schizophrenia appears to be expressed across a dynamic continuum of adjustment referred to as schizotypy. This model suggests that nonpsychotic schizotypic individuals should exhibit mild and transient forms of symptoms seen in full-blown schizophrenia. Given that depression and anxiety are reported to be comorbid with schizophrenia, the present study examined the relationship of psychometrically defined schizotypy with symptoms of depression and anxiety in a college student sample (n=1258). A series of confirmatory factor analyses indicated that a three-factor solution of positive schizotypy, negative schizotypy, and negative affect provided the best solution for self-report measures of schizotypy, anxiety, and depression. As hypothesized, the model indicated that symptoms of depression and anxiety are more strongly associated with the positive-symptom dimension of schizotypy than with the negative-symptom dimension. This is consistent with studies of schizophrenic patients and longitudinal findings that positive-symptom schizotypes are at risk for both mood and non-mood psychotic disorders, while negative-symptom schizotypes appear more specifically at risk for schizophrenia-spectrum disorders.
authors.affiliation: University of North Carolina at Greensboro, Department of Psychology, 296 Eberhart Building, Greensboro, NC 27402, USA. kelewand@uncg.edu
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Lewandowski
authors.forename: Neus
authors.initials: N
authors.lastname: Barrantes-Vidal
authors.forename: Rosemery O
authors.initials: RO
authors.lastname: Nelson-Gray
authors.forename: Carolina
authors.initials: C
authors.lastname: Clancy
authors.forename: Hayden O
authors.initials: HO
authors.lastname: Kepley
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Kwapil
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000209:etiology* / Q000523:psychology; D003863:Depression / Q000209:etiology* / Q000523:psychology; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D010555:Personality Inventory / Q000706:statistics & numerical data; D011594:Psychometrics; D012569:Schizotypal Personality Disorder / Q000150:complications*