title: Serum leptin levels in patients with allergic rhinitis.
abstract: OBJECTIVE
  To investigate the serum leptin levels in patients with allergic rhinitis during the symptomatic period.
  
  
  METHODS
  A randomized, prospective study was performed on 26 adult patients with allergic rhinitis and 20 control subjects with similar age, sex and body mass index in a tertiary otolaryngology center.
  
  
  RESULTS
  Leptin levels were 28.8 +/- 14.1 ng/mL in the patients with allergic rhinitis, and 20.8 +/- 13.5 ng/mL in the control group respectively. The difference between the groups was statistically significant (p = 0.04).
  
  
  CONCLUSIONS
  Serum leptin levels were found to be significantly higher in patients with allergic rhinitis in symptomatic period.
  
  
  CONCLUSIONS
  Apart from its primary role in the regulation of body weight and energy expenditure, leptin may have a role in the inflammatory process of the allergic rhinitis.
authors.affiliation: Department of Biochemistry, Mersin University, School of Medicine, Mersin, Turkey. munal@mersin.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Unal
authors.forename: Gülçin
authors.initials: G
authors.lastname: Eskandari
authors.forename: Necati
authors.initials: N
authors.lastname: Muşlu
authors.forename: Yavuz Selim
authors.initials: YS
authors.lastname: Pata
authors.forename: Yücel
authors.initials: Y
authors.lastname: Akbaş
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007249:Inflammation / Q000276:immunology; D020738:Leptin / Q000097:blood*; D008297:Male; D011446:Prospective Studies; D012220:Rhinitis / Q000097:blood* / Q000276:immunology
chemical_list: D020738:Leptin