title: Biochemistry. Loop grafting and the origins of enzyme species.
authors.affiliation: Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel. tawfik@weizmann.ac.il
authors.forename: Dan S
authors.initials: DS
authors.lastname: Tawfik
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D020134:Catalytic Domain; D019020:Directed Molecular Evolution; D019143:Evolution, Molecular; D015202:Protein Engineering; D013379:Substrate Specificity; D013869:Thiolester Hydrolases / Q000737:chemistry* / Q000378:metabolism*; D001618:beta-Lactamases / Q000737:chemistry / Q000378:metabolism*; D047090:beta-Lactams / Q000378:metabolism; D000099301:Hydroxyacylglutathione Hydrolase
chemical_list: D013869:Thiolester Hydrolases; D001618:beta-Lactamases; D047090:beta-Lactams; D000099301:Hydroxyacylglutathione Hydrolase; C409201:beta-lactamase IMP-1