title: Clinical research on monitoring CSFP through lumbar epidural pressure.
abstract: OBJECTIVE
  Explore the relationship between lumbar Epidural Pressure (LEDP) and CSFP through clinical studies and to determine whether LEDP can represent CSFP.
  
  
  METHODS
  We selected 150 cases of cerebral diseases at random for this study. A special mini transducer was implanted into the lumbar epidural space between the third and the 4th lumbar vertebra by means of a No. 18 Touhy needle for monitoring of LEDP. In the meantime, a traditional lumbar puncture was made between the 4th and the 5th lumbar vertebrae and CSFP, which was taken as the standard value, was measured using an ordinary catheter. The transducer was adjusted until the LEDP was equal to CSFP and was designated LEDP0. The LEDP0 was monitored continuously and was translated into a continuous curve. In each and every case, a lumbar puncture was repeated at 24, 48, 72 and 96 hours to obtain CSFP for comparison and to explore the relationship between LEDP0 and CSFP. While monitoring LEDP0, we observed the variation in pressure when the patient breathed, coughed, changed posture, and also if the clinical symptoms changed with intracranial hypertension.
  
  
  RESULTS
  The values of the intracranial pressure measured by these two methods were identical.
  
  
  CONCLUSIONS
  LEDP responded to the changes of CSFP.
authors.affiliation: Neurosurgery Department, Fuzhou General Hospital, Fuzhou, Fujian, China. liuzheng@vip.cvn.com.cn
authors.forename: Z
authors.initials: Z
authors.lastname: Liu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Dou
authors.forename: R
authors.initials: R
authors.lastname: Chen
authors.forename: X Z
authors.initials: XZ
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D015170:Cerebrospinal Fluid Pressure; D004824:Epidural Space / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000503:physiopathology*; D007427:Intracranial Pressure; D008159:Lumbar Vertebrae / Q000503:physiopathology; D008297:Male; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014160:Transducers, Pressure