The effect of interaction between hepatitis C virus and cigarette smoking on the risk of hepatocellular carcinoma.
We evaluated the interaction between hepatitis C virus (HCV) and cigarette smoking on death from hepatocellular cancer in The Japan Collaborative Cohort Study. The odds ratio of death from HCC for smoking was 9.60 (1.50-61.35) and 1.71(0.58-5.08) among anti-HCV positive and negative individuals, respectively.
Fujita
Y
Y
Department of Public Health, Kurume University School of Medicine, Kurume 830-0011, Japan. yf123@med.kurume-u.ac.jp
Shibata
A
A
Ogimoto
I
I
Kurozawa
Y
Y
Nose
T
T
Yoshimura
T
T
Suzuki
H
H
Iwai
N
N
Sakata
R
R
Ichikawa
S
S
Tamakoshi
A
A
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000401:mortality* / Q000821:virology; D015331:Cohort Studies; D005260:Female; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008113:Liver Neoplasms / Q000453:epidemiology / Q000401:mortality* / Q000821:virology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*