[The damage of the neural retina and of the retinal pigment epithelium of eyes of rats exposed to highly intensive visible light under alloxanic diabetes].
The experiments on white mongrel rats showed that the light with the intensity of 6000 1x lasting for 6 hours resulted the destruction of the retinal pigment epithelium, of the internal and the external neurosensory cellular processes with subsequent nuclei piknosis and radial glia replacement. On the 7th day after exposure to light focal effusion of the retina corresponding layers. Under the irradiation in diabetes the amount of cells with karyopyknosis increases in 1.6 times in comparision with the findings in case free of diabetes. Was found, that the alloxanic diabetes in its early stage increases the light impairment of the neurosensory cells of the retina.
Logvinov
S V
SV
Varakuta
E Iu
EIu
Potapov
A V
AV
D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000473:pathology*; D008027:Light; D008297:Male; D020419:Photoreceptor Cells, Vertebrate / Q000473:pathology* / Q000528:radiation effects; D010857:Pigment Epithelium of Eye / Q000473:pathology* / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000473:pathology* / Q000528:radiation effects
D000496:Alloxan