Pregnancy outcome after early detection of bacterial vaginosis.
OBJECTIVE
To assess if detecting bacterial vaginosis either in early pregnancy or at midtrimester may predict adverse pregnancy outcome in women at risk for preterm delivery.


METHODS
242 pregnant women with a previous preterm delivery were evaluated for bacterial vaginosis either in the first trimester (prior to 10+0 weeks) or in the second one (24-26 weeks). Adverse outcome was intended as miscarriage (< or =25 weeks), or premature delivery (< or =36+6).


RESULTS
The risk of adverse pregnancy outcome was significantly increased in women diagnosed at first trimester with bacterial vaginosis (OR: 4.56; 95% CI: 2.54-8.93); the same finding at midtrimester did not increase significantly the risk of preterm delivery.


CONCLUSIONS
Early screening for bacterial vaginosis in pregnant women who experienced a preterm delivery may help in predicting the risk of adverse outcome.
Guerra
Brunella
B
Department of Obstetrics and Gynecology, Policlinico S.Orsola-Malpighi, Alma Mater Studiorum-University of Bologna, Italy.
Ghi
Tullio
T
Quarta
Simona
S
Morselli-Labate
Antonio Maria
AM
Lazzarotto
Tiziana
T
Pilu
Gianluigi
G
Rizzo
Nicola
N
D000022:Abortion, Spontaneous / Q000382:microbiology; D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000382:microbiology*; D011256:Pregnancy Outcome; D011264:Pregnancy Trimesters; D047928:Premature Birth / Q000209:etiology*; D016585:Vaginosis, Bacterial / Q000150:complications*