title: Solid-phase synthesis of 1,3,4-oxadiazoline-5-thione derivatives from resin-bound acylhydrazines.
abstract: A new strategy for solid-phase synthesis of 2,5-disubstituted 1,3,4-oxadiazoles has been developed. The 1,3,4-oxadiazoline-5-thione derivatives were synthesized from resin-bound acylhydrazines in several steps providing 78-88% overall yields and excellent purity.
authors.affiliation: Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou 310028, People's Republic of China. liuzhanx@zju.edu.cn
authors.forename: Zhanxiang
authors.initials: Z
authors.lastname: Liu
authors.forename: Jinlong
authors.initials: J
authors.lastname: Zhao
authors.forename: Xian
authors.initials: X
authors.lastname: Huang
mesh_terms: D006834:Hydrazines / Q000737:chemistry*; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D006834:Hydrazines; D010069:Oxadiazoles