Neonatal pseudohypoparathyroidism.
The case of a neonate is presented who had early onset seizure associated with hypocalcemia, hyperphosphatemia, and raised parathyroid hormone. The infant did not have any stigmata of pseudohypoparathyroidism. The hypocalcemia was initially resistant to calcium therapy, but responded to vitamin D analog therapy. The diagnosis of 'neonatal pseudohypoparathyroidism' was entertained; the infant remained stable and seizure-free with normal serum biochemistry during 3 months of follow-up.
Narang
Manish
M
Department of Pediatrics, University College of Medical Sciences and GTB Hospital, New Delhi, India. manish_2710@yahoo.com
Salota
Rashim
R
Sachdev
Sudeep Singh
SS
D002117:Calcitriol / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D019587:Dietary Supplements; D006801:Humans; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D012640:Seizures / Q000209:etiology; D014807:Vitamin D / Q000031:analogs & derivatives / Q000627:therapeutic use
D010281:Parathyroid Hormone; D010710:Phosphates; D014807:Vitamin D; D002117:Calcitriol; D002118:Calcium