Risk of perinatal transmission of rubella and parvovirus B19 in Jordanian pregnant women.
The seroprevalence and the risk of perinatal transmission of rubella virus (RV) and human parvovirus B19 were assessed in 439 Jordanian pregnant women. Seroprevalence data indicate that 43.7%, 48.7% and 19% of women are susceptible to RV, parvovirus B19 infections and both, respectively. A total of 12.2% and 20.2% of RV susceptible women are at the first and second trimester of gestation, respectively. They are at risk of bearing infants with congenital rubella syndrome (CRS). However, 15% and 23% of parvovirus B19 susceptible women are at the first and second trimester of gestation, respectively. They are at risk of fetal loss or hydrops fetalis. Prenatal screening for these viruses, postpartum MMR vaccination and parvovirus B19 passive immunization are recommended.
Bdour
Salwa
S
Department of Biological Sciences, Faculty of Science, University of Jordan, Queen Rania Street, Amman, Jordan. bsalwa@ju.edu.jo
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D007597:Jordan / Q000453:epidemiology; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000276:immunology / Q000635:transmission* / Q000821:virology; D016732:Parvovirus B19, Human / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011264:Pregnancy Trimesters; D012306:Risk; D012409:Rubella / Q000453:epidemiology / Q000276:immunology / Q000635:transmission*; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral; C040901:rubella antibodies