title: [A study of mydocalm efficiency in the treatment of chronic headache of tension].
abstract: Mydocalm was used for the treatment of 31 patients, mean age 45 +/- 4 years, with chronic headache of tension in a dosage of 150 mg 3 times per day during 4 weeks. Twenty-six patients have completed the therapy course. Before- and after treatment, neurological status, dynamics of psychoautonomic disorders, an extent of anxiety and depression, quality of sleep, quality of life, pain syndrome measured by a number of tests, were assessed, along with electromyography and examination of nociceptive reflex. Subjective evaluation of the drug efficacy was taken into account as well. A marked positive effect of mydocalm was observed in 70% of patients, moderate effect--in 30%. A predictor of mydocalm efficacy was severity of muscle tonic syndrome.
authors.forename: A D
authors.initials: AD
authors.lastname: Solov'eva
authors.forename: E S
authors.initials: ES
authors.lastname: Akarachkova
authors.forename: S A
authors.initials: SA
authors.lastname: Gordeev
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004576:Electromyography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D010147:Pain Measurement / Q000187:drug effects; D012720:Severity of Illness Index; D018781:Tension-Type Headache / Q000188:drug therapy* / Q000503:physiopathology; D014049:Tolperisone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D009125:Muscle Relaxants, Central; D014049:Tolperisone