title: [Inter-laboratory validation studies of analytical method for determination of chloramphenicol in royal jelly].
abstract: Inter-laboratory validation studies were conducted in 6 laboratories to validate the analytical method for determination of chloramphenicol in royal jelly. Chloramphenicol spiked at the levels of 0.1 and 0.5 ppm was analyzed. Mean recoveries were 89 and 89%, reproducibility relative standard deviations (RSD(R)) were 10.5 and 6.8%, HORRAT(R) values were 0.5 and 0.4. Samples containing residues at the levels of 0.25 and 0.80 ppm were analyzed. Mean recoveries were 89 and 84%, RSD(R) were 9.8 and 12.3%, and HORRAT(R) values were 0.5 and 0.7. The determination limit was 0.05 ppm. These results show that this method has good performance.
authors.affiliation: Japan Food Research Laboratories Nagoya Branch, 4-5-13, Osu, Naka-ku, Nagoya 460-0011, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Fujita
authors.forename: Hiromi
authors.initials: H
authors.lastname: Osuka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Fujiki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yoneyama
authors.forename: Kiyoki
authors.initials: K
authors.lastname: Sengoku
authors.forename: Yoshimichi
authors.initials: Y
authors.lastname: Sumiya
authors.forename: Megumi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Yuri
authors.initials: Y
authors.lastname: Mizutani
authors.forename: Xiying
authors.initials: X
authors.lastname: Zhao
authors.forename: Tsuguo
authors.initials: T
authors.lastname: Hirose
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D002701:Chloramphenicol / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004350:Drug Residues / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D007753:Laboratories; D000099219:Royal Jelly
chemical_list: D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D005227:Fatty Acids; D000099219:Royal Jelly