title: Bovine pericardium (Tutopatch) wrap for hydroxyapatite implants.
abstract: OBJECTIVE
  To evaluate bovine pericardium (Tutopatch) as a wrapping material for hydroxyapatite implants in patients undergoing enucleation for uveal melanoma.
  
  
  METHODS
  Prospective cohort study of patients who had enucleation for uveal melanoma between January 2003 and August 2003 were included in the study. Any patient with less than 3 months follow-up was excluded. Enucleation was performed under general anaesthesia followed by insertion of hydroxyapatite implants wrapped in bovine pericardium (Tutopatch). The recti muscles were sutured directly to the wrap. The tenon's capsule and conjunctiva were closed in two layers. A conformer was inserted at 1 week and artificial eye at 2-3 months. The patients were followed up regularly and were assessed for cosmetic result, exposure of implant, and the need for any further surgical procedures.
  
  
  RESULTS
  A total of 19 patients (seven male and 12 female) were included in the study. Median age at diagnosis was 63 years (range 38-80 years). Median follow-up was 26 months (range 22-30 months). No patient developed postoperative complications of wound dehiscence. The overall cosmetic result was excellent in all the patients. The rate of postoperative complications compared favourably with published data using other wrapping materials/implants.
  
  
  CONCLUSIONS
  Tutopatch is a safe wrapping material for hydroxyapatite orbital implants in patients undergoing enucleation for uveal melanoma.
authors.affiliation: Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK. mohiteye@yahoo.co.uk
authors.forename: M
authors.initials: M
authors.lastname: Gupta
authors.forename: F
authors.initials: F
authors.lastname: Lyon
authors.forename: A D
authors.initials: AD
authors.lastname: Singh
authors.forename: P A
authors.initials: PA
authors.lastname: Rundle
authors.forename: I G
authors.initials: IG
authors.lastname: Rennie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001672:Biocompatible Materials; D002417:Cattle; D017886:Durapatite; D015353:Eye Enucleation / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000601:surgery*; D008875:Middle Aged; D020273:Orbital Implants; D010496:Pericardium; D011183:Postoperative Complications; D011446:Prospective Studies; D011474:Prosthesis Design; D016896:Treatment Outcome; D014604:Uveal Neoplasms / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite