Retrobulbar metastasis from gallbladder carcinoma after laparoscopic cholecystectomy. A case report.
Extra-abdominal metastases from gallbladder cancer are very rare; the sites outside the abdomen most frequently affected are the skin, bone and central nervous system. In the literature, only one case of orbital metastasis from gallbladder cancer has been reported, in a patient previously treated by open cholecystectomy. We report the case of a 53-year-old woman who underwent a laparoscopic cholecystectomy for symptomatic gallbladder stones. Postoperative histological examination revealed an unsuspected gallbladder adenocarcinoma. One month later she came to our observation after having developed diplopia and ophthalmic pain due to an orbital metastasis. We decided not to perform a surgical second look because of the already rapid dissemination of the malignant tumor. The few cases of uncommon gallbladder cancer metastases after laparoscopic cholecystectomy described in the literature are discussed, as well as the possible role of laparoscopy in the dissemination and localized seeding of malignant cells.
Puglisi
Francesco
F
Unit of General Surgery and Liver Transplantation, University of Bari, Italy. g.bros@tiscali.it
Capuano
Palma
P
Gentile
Antonia
A
Lobascio
Pierluigi
P
Russo
Silvana
S
Martines
Gennaro
G
Lograno
Giuseppe
G
Memeo
Vincenzo
V
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery*; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009366:Neoplasm Seeding; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed