title: Value of fat-suppressed PD-weighted TSE-sequences for detection of anterior and posterior cruciate ligament lesions--comparison to arthroscopy.
abstract: OBJECTIVE
  To evaluate fat-suppressed (FS) proton-density-weighted (PDw) turbo spin-echo (TSE) magnetic resonance imaging for the detection of anterior and posterior cruciate ligament lesions in comparison to arthroscopy.
  
  
  METHODS
  In a prospective study 31 knee joints were imaged on a 1.5T MR scanner (Vision, Siemens, Erlangen) prior to arthroscopy using following sequences: (a) sagittal FS-PDw/T2w TSE (TR/TE: 4009/15/105 ms); (b) sagittal PDw/T2w TSE (TR/TE:3800/15/105 ms). Further imaging parameters: slice thickness 3mm, FOV 160 mm, matrix 256 x 256. A total of 62 anterior and posterior cruciate ligaments (ACL/PCL) were evaluated, standard of reference was arthroscopy. Sensitivity, specificity, positive (ppv) and negative predictive value (npv) and accuracy were calculated.
  
  
  RESULTS
  Twenty-one cruciate ligament ruptures were detected in arthroscopy, 19 ACL- and 2 PCL-ruptures (on MRI 34/124, 25/62 ACL, 9/62 PCL lesions). For all four sequences in the 31 patients with arthroscopic correlation sensitivity, specificity, ppv, npv and accuracy were 86%, 98%, 95%, 93% and 94% for detection of tears, and 84%, 100%, 100%, 80% and 90% for ACL-ruptures respectively. The two PCL-ruptures were true positive in all sequences, one intact PCL was diagnosed as torn (false positive).
  
  
  CONCLUSIONS
  Fat-suppressed PDw/T2w TSE-MR sequences are comparable to PDw TSE sequences for the detection of ACL/PCL-lesions.
authors.affiliation: Department of Diagnostic Radiology, University Hospital of Schleswig-Holstein Campus Kiel, Arnold-Heller-Strasse 9, 24105 Kiel, Germany. f.schaefer@rad.uni-kiel.de
authors.forename: Fritz K W
authors.initials: FK
authors.lastname: Schaefer
authors.forename: Philipp J
authors.initials: PJ
authors.lastname: Schaefer
authors.forename: Joachim
authors.initials: J
authors.lastname: Brossmann
authors.forename: Christian
authors.initials: C
authors.lastname: Frahm
authors.forename: Claus
authors.initials: C
authors.lastname: Muhle
authors.forename: Ralf Erik
authors.initials: RE
authors.lastname: Hilgert
authors.forename: Martin
authors.initials: M
authors.lastname: Heller
authors.forename: Thomas
authors.initials: T
authors.lastname: Jahnke
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016118:Anterior Cruciate Ligament / Q000473:pathology*; D001182:Arthroscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007592:Joint Diseases / Q000175:diagnosis*; D007719:Knee Joint / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D016119:Posterior Cruciate Ligament / Q000473:pathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012421:Rupture / Q000175:diagnosis; D012680:Sensitivity and Specificity