title: False-positive amplified Mycobacterium tuberculosis direct test results for samples containing Mycobacterium leprae.
abstract: Nucleic acid amplification tests are widely used in mycobacteriology laboratories to rapidly detect Mycobacterium tuberculosis complex directly in clinical specimens. A positive result provides an early diagnosis of tuberculosis, allowing initiation of appropriate therapy and public health measures.
authors.affiliation: Ministry of Health and Long-Term Care, Public Health Laboratories Branch, TB and Mycobacteriology, 81 Resources Road, Etobicoke, Ontario M9P 3T1, Canada. pam.chedore@moh.gov.on.ca
authors.forename: Pam
authors.initials: P
authors.lastname: Chedore
authors.forename: George
authors.initials: G
authors.lastname: Broukhanski
authors.forename: Zev
authors.initials: Z
authors.lastname: Shainhouse
authors.forename: Frances
authors.initials: F
authors.lastname: Jamieson
mesh_terms: D000328:Adult; D003951:Diagnostic Errors; D005189:False Positive Reactions; D006801:Humans; D007918:Leprosy / Q000175:diagnosis; D008198:Lymph Nodes / Q000382:microbiology*; D008297:Male; D009166:Mycobacterium leprae / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D016133:Polymerase Chain Reaction; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology