Strategies for developing therapeutic application of human embryonic stem cells.
The ongoing debate on human embryonic stem cells (hESC) is fueled by ethical concerns but also by the legitimate hope that hESC could one day be used for the cure of presently untreatable human diseases. Here we discuss current approaches to and constraints upon hESC differentiation and describe their potential application in clinical medicine.
Raikwar
Sudhanshu P
SP
Department of Internal Medicine and Veterans Affairs Medical Center, Iowa City, Iowa, USA.
Mueller
Thomas
T
Zavazava
Nicholas
N
D002454:Cell Differentiation; D002478:Cells, Cultured; D033041:Embryo Research; D006801:Humans; D010641:Phenotype; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology