title: The relevance of convection in clinical practice: a critical review of the literature.
abstract: Convective treatments (high-flux hemodialysis (HD), hemodiafiltration and hemofiltration) are characterized by enhanced removal of middle and large molecular weight solutes compared with conventional low-flux HD. As these molecules are claimed to play an important role in the genesis of many complications of chronic HD, the availability of these techniques represented an intriguing innovation and a possible means to improve the still poor prognosis of HD patients. Here we will critically review the most important published studies comparing convective treatments with low-flux HD on chronic morbidity, preservation of residual renal function, and long-term survival.
authors.affiliation: Department of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Pozzoni
authors.forename: Salvatore
authors.initials: S
authors.lastname: Filippo
authors.forename: Celestina
authors.initials: C
authors.lastname: Manzoni
authors.forename: Francesco
authors.initials: F
authors.lastname: Locatelli
mesh_terms: D017583:Hemodiafiltration / Q000009:adverse effects / Q000592:standards; D006440:Hemofiltration / Q000009:adverse effects / Q000592:standards; D006801:Humans; D007668:Kidney / Q000502:physiology; D008970:Molecular Weight; D009017:Morbidity; D006435:Renal Dialysis / Q000009:adverse effects / Q000592:standards; D017582:Renal Replacement Therapy / Q000009:adverse effects / Q000592:standards*; D015996:Survival Rate; D016896:Treatment Outcome