Comparison of human (and other) genome browsers.
The sequence of the human genome provides a scaffold on which numerous annotations, such the locations of genes, can be laid. Genome browsers have been created to allow the simultaneous display of multiple annotations within a graphical interface. In addition, they provide the ability to search for markers and sequences, to extract annotations for specific regions or for the whole genome and to act as a central starting point for genomic research. This review describes the basic functionality of genome browsers and compares three of them: the University of California Santa Cruz (UCSC) Genome Browser, the Ensembl Genome Browser and the NCBI MapViewer.
Furey
Terrence S
TS
Institute for Genome Sciences and Policy, Duke University, Box 3382, Durham, NC 27708, USA. terry.furey@duke.edu
D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D030561:Databases, Nucleic Acid; D005819:Genetic Markers; D014644:Genetic Variation; D016678:Genome; D015894:Genome, Human; D006801:Humans; D012984:Software
D005819:Genetic Markers; D004247:DNA