title: One year results of a randomised controlled multi-centre study comparing Prolene and Vypro II-mesh in Lichtenstein hernioplasty.
abstract: A standard polypropylene mesh used in Lichtenstein's operation induces a strong foreign tissue reaction with potential harmful effects. A mesh with less polypropylene could possibly be beneficial. Six hundred men with primary unilateral inguinal hernias were randomised to Lichtenstein's operation using a Prolene- or Vypro II-mesh in six centres. The patients were blinded to which mesh they received. A validated questionnaire assessing recurrence and pain along with SF-36 Health Survey was sent after 1 year to all patients and a selected group was clinically examined. Of the 591 operated patients, 526 (89.0%) returned the questionnaire. 188 patients had some complaints or sensations of which 111 patients were clinically examined. The mean follow-up time was 13.6 (SD. 4.0) months. The incidence of hernia recurrence (four vs. four patients) and neuralgia (three vs. four patients) did not differ between Prolene and Vypro II-groups, respectively. One Vypro II-patient was re-operated due to neuralgia. There was no difference in the SF-36 scores. The results of Lichtenstein's operation with either Prolene or Vypro II do not seem to differ significantly.
authors.affiliation: Center for Surgical Sciences, Karolinska Institutet, Department of Surgery, Södertälje Hospital, 15286 Södertälje, Sweden. sven.bringman@cfss.ki.se
authors.forename: S
authors.initials: S
authors.lastname: Bringman
authors.forename: S
authors.initials: S
authors.lastname: Wollert
authors.forename: J
authors.initials: J
authors.lastname: Osterberg
authors.forename: S
authors.initials: S
authors.lastname: Smedberg
authors.forename: H
authors.initials: H
authors.lastname: Granlund
authors.forename: G
authors.initials: G
authors.lastname: Felländer
authors.forename: T
authors.initials: T
authors.lastname: Heikkinen
mesh_terms: D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000209:etiology; D010149:Postoperative Pain; D011098:Polyglactin 910; D011126:Polypropylenes; D011183:Postoperative Complications; D012008:Recurrence; D016037:Single-Blind Method; D013526:Surgical Mesh
chemical_list: D011126:Polypropylenes; D011098:Polyglactin 910