False-positive amplified Mycobacterium tuberculosis direct test results for samples containing Mycobacterium leprae.
Nucleic acid amplification tests are widely used in mycobacteriology laboratories to rapidly detect Mycobacterium tuberculosis complex directly in clinical specimens. A positive result provides an early diagnosis of tuberculosis, allowing initiation of appropriate therapy and public health measures.
Chedore
Pam
P
Ministry of Health and Long-Term Care, Public Health Laboratories Branch, TB and Mycobacteriology, 81 Resources Road, Etobicoke, Ontario M9P 3T1, Canada. pam.chedore@moh.gov.on.ca
Broukhanski
George
G
Shainhouse
Zev
Z
Jamieson
Frances
F
D000328:Adult; D003951:Diagnostic Errors; D005189:False Positive Reactions; D006801:Humans; D007918:Leprosy / Q000175:diagnosis; D008198:Lymph Nodes / Q000382:microbiology*; D008297:Male; D009166:Mycobacterium leprae / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D016133:Polymerase Chain Reaction; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology