title: Personality profile in type I alcoholism: long duration of alcohol intake and low serotonergic activity are predictive factors of anxiety proneness.
abstract: The aim of the present study was to further investigate personality profiles in male type I alcohol-dependent subjects (n = 33), in relation to central serotonergic neurotransmission, history of excessive alcohol consumption and present use of tobacco. Central serotonergic neurotransmission was assessed by the prolactin (PRL) response to D-fenfluramine. By using the Temperament and Character Inventory and the Karolinska Scales of Personality, all subjects self-rated their personality profile. The results showed that individuals with low PRL response and long duration of excessive alcohol consumption had significantly higher anxiety proneness, and that years of excessive alcohol consumption was the strongest predictor. Long duration of excessive alcohol consumption thus appears to have an influence on personality traits in male type I alcohol-dependent individuals and these personality traits may therefore be a consequence of, rather than preceding, alcoholism in these individuals.
authors.affiliation: Department of Psychology, Göteborg University, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Berglund
authors.forename: C
authors.initials: C
authors.lastname: Fahlke
authors.forename: U
authors.initials: U
authors.lastname: Berggren
authors.forename: M
authors.initials: M
authors.lastname: Eriksson
authors.forename: J
authors.initials: J
authors.lastname: Balldin
mesh_terms: D000328:Adult; D000368:Aged; D000374:Aggression; D000437:Alcoholism / Q000150:complications / Q000523:psychology*; D001007:Anxiety / Q000150:complications / Q000523:psychology*; D005277:Fenfluramine; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D010556:Personality Tests; D011237:Predictive Value of Tests; D011388:Prolactin / Q000097:blood; D011569:Psychiatric Status Rating Scales; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*; D017367:Selective Serotonin Reuptake Inhibitors; D012907:Smoking / Q000523:psychology; D009435:Synaptic Transmission / Q000502:physiology; D014029:Tobacco Use Disorder / Q000523:psychology
chemical_list: D005277:Fenfluramine; D011388:Prolactin; D012701:Serotonin; D017367:Selective Serotonin Reuptake Inhibitors