Neuroimaging and serologic markers of neurologic injury after cardiac arrest.
Determining prognosis in the setting of hypoxic-ischemic injury following cardiac arrest is difficult based solely on clinical parameters in the patient who is critically ill. The article discusses bio- chemical markers in the blood and in the cerebrospinal fluid that are evaluated for prognostic information, along with radiologic indicators of anoxic cerebral damage. It includes a recommended algorithm using a combination of serologic and radiologic markers of cerebral injury for assessing prognosis in the patient who is comatose following cardiac arrest.
Geraghty
Madeleine C
MC
Department of Neurology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Madison, WI 53792, USA.
Torbey
Michel T
MT
D001786:Blood Glucose; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D002545:Brain Ischemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D003402:Creatine Kinase / Q000097:blood; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D009418:S100 Proteins / Q000097:blood; D014057:Tomography, X-Ray Computed
D001786:Blood Glucose; D009418:S100 Proteins; D019344:Lactic Acid; D003402:Creatine Kinase