Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.
Samaranayake
Mala
M
Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
Bujnicki
Janusz M
JM
Carpenter
Michael
M
Bhagwat
Ashok S
AS
D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies / Q000276:immunology; D020137:Base Pair Mismatch; D003596:Cytosine / Q000378:metabolism*; D043525:Cytosine Deaminase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004247:DNA / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004249:DNA Damage; D004260:DNA Repair; D003641:Deamination; D006801:Humans; D007316:Insemination, Artificial, Heterologous; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016296:Mutagenesis
D000906:Antibodies; D003596:Cytosine; D004247:DNA; D043525:Cytosine Deaminase