title: [Border-line smooth-muscle tumor of the uterus: analysis of 131 patients].
abstract: OBJECTIVE
  To investigate whether the border-line uterine smooth-muscle tumor is different from leiomyoma or leiomyosarcoma in history and clinical manifestations.
  
  
  METHODS
  The medical records of 131 surgically treated patients suffering from the so-called cellular leiomyoma or mitotically active leiomyoma of the uterus treated from 1984 to 2002 were retrospectively reviewed. All pathological sections of these patients were reviewed by a senior pathologist. Chi-square test and Kaplan-Meier life table were used for statistical analysis.
  
  
  RESULTS
  The overall 5-year survival rate of patients with the border-line uterine smooth-muscle tumors was 100%, however, 19.1% (24/131) of whom developed a late recurrence and 8 patients had repeated recurrences with a more shortened course and aggressive potential changes of mitosis and cellular atypia. The overall 5-year survival rate the patients with recurrence was 91.7%, but only 75.0% for those with repeated recurrences.
  
  
  CONCLUSIONS
  Patients with border-line uterine smooth-muscle tumor do possess some difference in nature from the leiomyoma or leimyosarcoma. Long-term follow-up is very important for these patients after surgery.
authors.affiliation: Department of Gynecological Oncology, Cancer Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. mskd2@sina.com
authors.forename: Shao-kang
authors.initials: SK
authors.lastname: Ma
authors.forename: Hong-tu
authors.initials: HT
authors.lastname: Zhang
authors.forename: Ling-ying
authors.initials: LY
authors.lastname: Wu
authors.forename: Li-ying
authors.initials: LY
authors.lastname: Liu
authors.forename: Bin
authors.initials: B
authors.lastname: Li
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D018235:Smooth Muscle Tumor / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate; D014594:Uterine Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery