title: Recurrence rates and long-term follow-up after laser resurfacing as a treatment for widespread actinic keratoses on the face and scalp.
abstract: BACKGROUND
  Diffuse widespread actinic keratoses are difficult to treat, have a tendency toward higher recurrence rates, and therefore require ablative treatment. Laser resurfacing is one of the treatment modalities that can treat whole surface areas.
  
  
  OBJECTIVE
  To evaluate patients who underwent laser resurfacing for widespread actinic keratoses with long-term follow-up for recurrence rates, time until new lesions occur, and the most common side effects.
  
  
  METHODS
  Retrospective case-control study from 25 patients who underwent laser resurfacing for widespread actinic keratoses on the scalp, forehead, or full face at our department. Follow-up varied from 7 to 70 months. Recurrence rates, adverse effects, and improvement were analyzed through chart analysis.
  
  
  RESULTS
  The mean average follow-up was 39 months. Forty-four percent of the patient shad no recurrence during the time period. Fifty-six percent of the patients developed new lesions after treatment but only a few. Of the recurrences, 20% occurred within 1 year and 36% occurred after 1 year. The most common short- and long-term side effects were infections (12%), hypopigmentation (48%), hyperpigmentation (8%), acne (12%), milia (12%), scar formation (8%), and atrophic and/or easily bruised skin (20%).
  
  
  CONCLUSIONS
  Laser resurfacing is an effective treatment modality for diffuse widespread actinic keratoses with long-term recurrence-free intervals.
authors.affiliation: Department of Dermatology, University Hospital Maastricht, Maastricht, The Netherlands.
authors.forename: Judith U
authors.initials: JU
authors.lastname: Ostertag
authors.forename: Patricia J F
authors.initials: PJ
authors.lastname: Quaedvlieg
authors.forename: Martino H A M
authors.initials: MH
authors.lastname: Neumann
authors.forename: Gertruud A
authors.initials: GA
authors.lastname: Krekels
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005145:Face; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000601:surgery*; D053685:Laser Therapy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011230:Precancerous Conditions / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D012535:Scalp; D012878:Skin Neoplasms / Q000601:surgery*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects