Marginal zone lymphoma with a dual cutaneous and leukemic presentation and an aberrant myeloid-monocytic phenotype.
Marginal zone lymphoma (MZL) is an indolent neoplasm of mature B cells, classified by the World Health Organization into three categories: nodal, splenic, and extranodal MZL of mucosa-associated lymphoid tissue (MALT lymphoma). We present an unusual case of MZL with cutaneous, leukemic, and bone marrow involvement at presentation and expression of an aberrant myeloid-monocytic phenotype. This case is best classified as MZL of leukemic subtype.
Keehn
Connie A
CA
Department of Pathology, University of south Florida college of Medicine, Tampa, FL, USA. ckeehn@hsc.usf.edu
Cualing
Hernani
H
D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D001854:Bone Marrow Cells / Q000378:metabolism / Q000473:pathology*; D019070:Cell Lineage; D002471:Cell Transformation, Neoplastic; D017809:Fatal Outcome; D006801:Humans; D007938:Leukemia / Q000378:metabolism / Q000473:pathology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009000:Monocytes / Q000378:metabolism / Q000473:pathology*; D010641:Phenotype; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*
D014408:Biomarkers, Tumor