Measurement of diffusion through calcium alginate gel matrices.
The diffusion of high molecular weight dextran samples and low molecular weight quinine sulphate in homogenous calcium alginate gel matrices was studied. An experimental design suitable for studying the diffusion of substances from or through a gel sample was established. The experimental results indicate that the different types of molecules diffuse in the gel by different mechanisms. The diffusion rate of the molecules in the gel is dependent on gel composition.
Holte
O
O
School of Pharmacy, University of Oslo, Norway.
Tønnesen
H H
HH
Karlsen
J
J
D000464:Alginates / Q000737:chemistry*; D000465:Algorithms; D002118:Calcium / Q000032:analysis; D003911:Dextrans; D004058:Diffusion; D005782:Gels; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008970:Molecular Weight; D011803:Quinine / Q000737:chemistry
D000464:Alginates; D003911:Dextrans; D005782:Gels; D006603:Hexuronic Acids; D020723:Glucuronic Acid; D011803:Quinine; D002118:Calcium