title: Pregnancy outcome after early detection of bacterial vaginosis.
abstract: OBJECTIVE
  To assess if detecting bacterial vaginosis either in early pregnancy or at midtrimester may predict adverse pregnancy outcome in women at risk for preterm delivery.
  
  
  METHODS
  242 pregnant women with a previous preterm delivery were evaluated for bacterial vaginosis either in the first trimester (prior to 10+0 weeks) or in the second one (24-26 weeks). Adverse outcome was intended as miscarriage (< or =25 weeks), or premature delivery (< or =36+6).
  
  
  RESULTS
  The risk of adverse pregnancy outcome was significantly increased in women diagnosed at first trimester with bacterial vaginosis (OR: 4.56; 95% CI: 2.54-8.93); the same finding at midtrimester did not increase significantly the risk of preterm delivery.
  
  
  CONCLUSIONS
  Early screening for bacterial vaginosis in pregnant women who experienced a preterm delivery may help in predicting the risk of adverse outcome.
authors.affiliation: Department of Obstetrics and Gynecology, Policlinico S.Orsola-Malpighi, Alma Mater Studiorum-University of Bologna, Italy.
authors.forename: Brunella
authors.initials: B
authors.lastname: Guerra
authors.forename: Tullio
authors.initials: T
authors.lastname: Ghi
authors.forename: Simona
authors.initials: S
authors.lastname: Quarta
authors.forename: Antonio Maria
authors.initials: AM
authors.lastname: Morselli-Labate
authors.forename: Tiziana
authors.initials: T
authors.lastname: Lazzarotto
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Pilu
authors.forename: Nicola
authors.initials: N
authors.lastname: Rizzo
mesh_terms: D000022:Abortion, Spontaneous / Q000382:microbiology; D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000382:microbiology*; D011256:Pregnancy Outcome; D011264:Pregnancy Trimesters; D047928:Premature Birth / Q000209:etiology*; D016585:Vaginosis, Bacterial / Q000150:complications*