title: Usefulness of multidetector row spiral computed tomography with 64- x 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses.
abstract: Eighty-four patients with suspected coronary artery disease were studied to determine the accuracy of noninvasive coronary angiography using a multidetector computed tomographic scanner with 64- x 0.6-mm collimation and 330-ms gantry rotation. All coronary artery segments with a diameter >1.5 mm were assessed with respect to stenoses >50% decreased diameter. Results were compared with quantitative coronary angiographic findings. After exclusion of unevaluable coronary segments (4%), multidetector computed tomography demonstrated a sensitivity of 93%, a specificity of 97%, and a negative predictive value of 100% in a per-segment analysis. In a per-artery analysis, 15 of 336 arteries (4%) were unevaluable. Sensitivity and specificity in evaluable arteries were 95% and 93%, respectively. In a per-patient analysis (81 of 84 patients included), sensitivity and specificity were 96% and 91%, respectively.
authors.affiliation: Department of Internal Medicine II, University of Erlangen, Erlangen, Germany. dieter.ropers@rzmail.uni-erlangen.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Ropers
authors.forename: Johannes
authors.initials: J
authors.lastname: Rixe
authors.forename: Katharina
authors.initials: K
authors.lastname: Anders
authors.forename: Axel
authors.initials: A
authors.lastname: Küttner
authors.forename: Ulrich
authors.initials: U
authors.lastname: Baum
authors.forename: Werner
authors.initials: W
authors.lastname: Bautz
authors.forename: Werner G
authors.initials: WG
authors.lastname: Daniel
authors.forename: Stephan
authors.initials: S
authors.lastname: Achenbach
mesh_terms: D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D036542:Tomography, Spiral Computed / Q000295:instrumentation*