title: Antimalarial activity of methylpiperazinyl-substituted benzophenone-based farnesyltransferase inhibitors.
authors.affiliation: Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität München, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Kettler
authors.forename: J
authors.initials: J
authors.lastname: Wiesner
authors.forename: R
authors.initials: R
authors.lastname: Ortmann
authors.forename: H M
authors.initials: HM
authors.lastname: Dahse
authors.forename: H
authors.initials: H
authors.lastname: Jomaa
authors.forename: M
authors.initials: M
authors.lastname: Schlitzer
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000494:pharmacology*; D001577:Benzophenones / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D051231:Farnesyltranstransferase / Q000037:antagonists & inhibitors*; D005982:Glutathione Transferase / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D010879:Piperazines / Q000494:pharmacology*; D010963:Plasmodium falciparum / Q000187:drug effects / Q000254:growth & development; D013329:Structure-Activity Relationship
chemical_list: D000962:Antimalarials; D001577:Benzophenones; D004791:Enzyme Inhibitors; D007202:Indicators and Reagents; D010879:Piperazines; D005982:Glutathione Transferase; D051231:Farnesyltranstransferase