Histopathologic lesions of diabetes mellitus in a domestic ferret.
A 2-year-did ferret was referred with a diagnosis of diabetes mellitus. The animal died despite insulin therapy and was submitted for necropsy. Light microscopic examination revealed a mild hepatic lipidosis and pancreatic lesions consisting of a diffuse vacuolation of the Langerhans' islet cells with a periodic acid-Schiff positive material compatible with glycogen.
Benoit-Biancamano
Marie-Odile
MO
Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, 3200, rue Sicotte, St-Hyacinthe, Québec J2S 2M2. marie-odile.benoit-biancamano@umontreal.ca
Morin
Michel
M
Langlois
Isabelle
I
D000818:Animals; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D005289:Ferrets; D006003:Glycogen / Q000032:analysis; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000473:pathology*; D010179:Pancreas / Q000473:pathology; D010503:Periodic Acid-Schiff Reaction / Q000662:veterinary; D014617:Vacuoles / Q000473:pathology
D007004:Hypoglycemic Agents; D007328:Insulin; D006003:Glycogen