title: Elevated total and isoenzyme forms of acid phosphatase in falciparum malaria.
abstract: The activities of total serum acid phosphatase (E.C. 3.1.3.2) and of two of its isoenzymes, tartrate-resistant acid phosphatase and erythrocyte-specific acid phosphatase were measured in 109 adult male and female patients presenting acute falciparum malaria infection, and a normal, healthy control group comprised of 82 subjects. All the three forms of acid phosphatase were found to be significantly (p<0.05) higher during infection as compared to their activity in the control group. This result suggests that the measurement of acid phosphatase, particularly the erythrocyte isoenzyme, in serum could be potentially used as a biomarker of acute falciparum malaria infection.
authors.affiliation: Chemistry Programme, School of Science, Abubakar Tafawa Balewa University, PMB 0248 Bauchi, Nigeria. ihgarba2002@yahoo.com
authors.forename: Ibrahim H
authors.initials: IH
authors.lastname: Garba
authors.forename: Donatien
authors.initials: D
authors.lastname: Gatsing
authors.forename: Gregory
authors.initials: G
authors.lastname: Ubom
mesh_terms: D000135:Acid Phosphatase / Q000097:blood*; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D016778:Malaria, Falciparum / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria
chemical_list: D007527:Isoenzymes; D000135:Acid Phosphatase