Labdane diterpenes from Juniperus communis L. berries.
A phytochemical study of the methanol extract of Juniperus communis berries was undertaken. The crude extract was analysed by HPLC-UV and the isolation of the minor compounds was performed by centrifugal partition chromatography. By this means, five diterpenes were isolated, one of which was a new labdane diterpene 15,16-epoxy-12-hydroxy-8(17),13(16),14-labdatrien-19-oic acid. The structures of the isolated compounds were elucidated by spectroscopic methods, including UV, NMR, MS and HR-MS.
Martin
Anne Marie
AM
Laboratory of Pharmacognosy and Phytochemistry, University of Geneva, Geneva, Switzerland.
Queiroz
Emerson Ferreira
EF
Marston
Andrew
A
Hostettmann
Kurt
K
D002853:Chromatography, Liquid / Q000379:methods; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D018653:Juniperus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013056:Spectrophotometry, Ultraviolet
D004224:Diterpenes; C433017:labdane