Solid-phase synthesis with resin-bound triarylbismuthanes: traceless and multidirectional cleavage of unsymmetrical biphenyls.
A multistep solid-phase organic synthesis with resin-bound bismuth linker is described. The flexibilities inherent in this system through novel chemoselective cross-coupling reactions, in conjunction with multidirectional and/or traceless cleavage methodologies, are exploited.
Rasmussen
L Kyhn
LK
Department of Medicinal Chemistry, H. Lundbeck A/S, 9 Ottiliavej, DK-2500 Valby, Denmark.
Begtrup
Mikael
M
Ruhland
Thomas
T
D001713:Biphenyl Compounds / Q000737:chemistry*; D001729:Bismuth / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D001713:Biphenyl Compounds; D001729:Bismuth; D001897:Boronic Acids; C010574:biphenyl