title: Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions.
abstract: [reaction: see text]. An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.
authors.affiliation: Department of Chemistry, University of Montana, Missoula, Montana 59812, USA.
authors.forename: Jasmina
authors.initials: J
authors.lastname: Nikodinovic
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Dinges
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Bergmeier
authors.forename: Mark C
authors.initials: MC
authors.lastname: McMills
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Wright
authors.forename: Nigel D
authors.initials: ND
authors.lastname: Priestley
mesh_terms: D000332:Aerobiosis; D000693:Anaerobiosis; D005663:Furans / Q000737:chemistry* / Q000378:metabolism; D018942:Macrolides / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012240:Rhodococcus / Q000378:metabolism*; D013237:Stereoisomerism
chemical_list: D005663:Furans; D018942:Macrolides; C514123:methyl nonactate; C050476:nonactin