Platelet interactions with vessel wall components during thrombogenesis.
We discuss the interrelationships of platelet glycoprotein receptors, von Willebrand factor, collagen, non-collagen matrix protein, and vascular cells in the complex events of platelet plug and subsequent thrombus formation.
Roon Center for Arteriosclerosis and Thrombosis, Division of Experimental Hemostasis and Thrombosis, Department of Molecular and Experimental Medicine, The Scripps Research Institute-MEM 175, La Jolla, CA 92037, USA. ruggeri@scripps.edu
Zaverio M
ZM
Ruggeri
D000818:Animals; D004730:Endothelium, Vascular / Q000473:pathology*; D016326:Extracellular Matrix Proteins; D006801:Humans; D010973:Platelet Adhesiveness; D011956:Receptors, Cell Surface; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology; D014841:von Willebrand Factor
D016326:Extracellular Matrix Proteins; D011956:Receptors, Cell Surface; D014841:von Willebrand Factor