The photomediated reaction of alkynes with cycloalkanes.
In the presence of a photomediator such as benzophenone, alkynes with electron-withdrawing groups react with cycloalkanes to give vinyl cycloalkanes. The reaction involves the regiospecific addition of a photochemically generated cycloalkyl radical to the beta-carbon of the alkyne. The stereochemical outcome of the reaction depends on the nature of the photomediator and alkyne used.
Doohan
Roísín A
RA
Department of Chemistry, National University of Ireland, Galway, Ireland.
Hannan
John J
JJ
Geraghty
Niall W A
NW