[Renal cell carcinoma with bilateral adrenal and small intestinal metastases: a case report].
A 69-year-old man who had a complaint of melena and hematemesis was referred to our hospital for further evaluation and treatment of renal masses, bilateral adrenal swelling and a tumor in the small intestine. The abdominal CT scan demonstrated two tumors sized 45 mm and 15 mm in diameter, located in the center and lower pole of the left kidney. Bilateral adrenal swelling and a small intestinal tumor with invagination were also observed. We diagnosed left renal cell carcinomas with bilateral adrenal metastases or hyperplasia, and a primary or metastatic small intestinal tumor. He received left radical nephrectomy, right adrenalectomy, and small intestinal resection. Pathological diagnosis was renal cell carcinoma, granular cell carcinoma, G2>G3>G1, INFalpha, v (+), pT1a, pM1, Stage IV. Bilateral adrenal swelling and small intestinal tumor were metastases from the renal cell carcinoma After operation, we administered interferon-alpha and steroid replacement. He died after 27-month follow-up period because of renal cell carcinoma. Renal cell carcinoma with simultaneous metastases to bilateral adrenal glands and the small intestine is extremely rare.
Department of Urology, Tsukuba Medical Center Hospital.
Satoshi
S
Ando
Yoshiharu
Y
Fukuhara
Jun
J
Miyazaki
Kazunori
K
Hattori
Sadamu
S
Tsukamoto
Shiro
S
Hinotsu
Toru
T
Shimazui
Hideyuki
H
Akaza
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006396:Hematemesis / Q000209:etiology; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D007421:Intestine, Small; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008297:Male; D008551:Melena / Q000209:etiology