Spontaneous recovery of steroid-induced osteopenia.
We report a case of an adolescent girl treated with high-dose oral steroids for prolonged coughing thought to be secondary to unstable asthma. Iatrogenic adrenal suppression led to clinical appearance of Cushing syndrome and associated bilateral early post-capsular cataracts, slowing of growth velocity and osteopenia. After weaning off steroids, there was a spontaneous increase in aeral lumbar bone mineral density and also catch-up growth evident over a 5-year period.
Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, Victoria, Australia.
Tiziana G
TG
Gozzi
Peter J
PJ
Simm
Fergus J
FJ
Cameron
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000188:drug therapy; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D001239:Inhalation; D014739:Victoria
D000305:Adrenal Cortex Hormones