Comparative study of MTA and other materials in retrofilling of pulpless dogs' teeth.
This in vivo study compared the effect of mineral trioxide aggregate (MTA), IRM, Super EBA and ZOE in a puttylike consistency, used as retrofilling materials, in the healing process of periapical tissue of pulpless dogs' teeth submitted to a conventional retrofilling technique. Twenty-four premolars obtained from three dogs were used. At the first intervention, the animals were anesthetized, coronal access was obtained and pulpectomy was done. Root canals were kept open to the oral environment for 180 days to induce the formation of apical lesions. After surgical removal of the lesions with curettes, 2 mm of the apical root was cut out perpendicular to the long axis of the teeth, and root-end cavities were shaped with a low-speed round bur. The bone cavities were irrigated and dried, and the root-end cavities were filled with MTA, IRM, Super EBA and ZOE in a puttylike consistency. The bone cavities were passively filled with blood and flaps were sutured. The coronal access openings were cleaned and double-sealed with ZOE and amalgam. After 180 days, the animals were killed by anesthetic overdose, maxilla and mandible were removed and the pieces were processed for histomorphologic analysis. Data were evaluated blindly on the basis of several histopathologic events and the scores obtained were analyzed statistically using the Kruskal Wallis test. No significant differences were observed among MTA, Super EBA and IRM (p>0.05). However, ZOE had a significantly more negative influence on the apical healing (p<0.05). In conclusion, MTA, Super EBA and IRM had similar histopathologic effects among each other and better performance than ZOE used in a puttylike consistency. Furthermore, only MTA stimulated hard tissue deposition in direct contact with the retrofilling material, even when it was inserted under critical conditions.
Discipline of Endodontics, Department of Restorative Dentistry, Faculty of Dentistry of Araçatuba, São Paulo State University (UNESP), Brazil. bernabe@foa.unesp.br
Pedro Felício Estrada
PF
Bernabé
Roberto
R
Holland
Ricardo
R
Morandi
Valdir
V
de Souza
Mauro Juvenal
MJ
Nery
José Arlindo
JA
Otoboni Filho
Eloi
E
Dezan Junior
João Eduardo
JE
Gomes-Filho
D017607:Aluminum Compounds / Q000627:therapeutic use*; D000818:Animals; D001047:Apicoectomy; D017610:Calcium Compounds / Q000627:therapeutic use*; D003475:Curettage; D003739:Dental Cementum / Q000473:pathology; D003804:Dentin / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D004285:Dogs; D004338:Drug Combinations; D008768:Methylmethacrylates / Q000627:therapeutic use; D010087:Oxides / Q000627:therapeutic use*; D010483:Periapical Diseases / Q000473:pathology / Q000601:surgery / Q000628:therapy; D010486:Periapical Tissue / Q000473:pathology; D011670:Pulpectomy; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D018915:Root Canal Preparation; D017640:Silicates / Q000627:therapeutic use*; D016037:Single-Blind Method; D013997:Time Factors; D019553:Tooth, Nonvital / Q000628:therapy*; D014945:Wound Healing; D015035:Zinc Oxide-Eugenol Cement / Q000627:therapeutic use
D017607:Aluminum Compounds; D017610:Calcium Compounds; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; D008768:Methylmethacrylates; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; D015035:Zinc Oxide-Eugenol Cement; C086631:mineral trioxide aggregate; C031667:IRM cement; C084074:Super EBA