[Mechanic's hands: a characteristic cutaneous sign of antisynthetase syndrome].
"Mechanic's hands" are a characteristic cutaneous sign of idiopathic inflammatory myositis. We describe the case of a 61-year-old male patient who was diagnosed with idiopathic polymyositis and non-specific interstitial lung disease in 1999, and three years later developed scaly, fissured hyperkeratotic lesions on the lateral and palmar surfaces of the first three fingers of both hands, with little pruritus. The presence of the anti-Jo-1 antisynthetase antibody in the patient's serum, the finding of skin lesions characteristic of "mechanic's hands" and the patient's other systemic clinical manifestations made it possible to establish the diagnosis of "antisynthetase syndrome."
Blanco
Susana
S
Servicio de Dermatología, Hospital de Cabueñes, Cabueñes s/n, 33394 Gijón, Spain. susanabb@telecable.es
Rodríguez
Eloy
E
Galache
Cristina
C
Cosme Alvarez-Cuesta
César
C
Nosti
Dolores
D
D000974:Antibodies, Antinuclear / Q000097:blood; D003882:Dermatomyositis / Q000097:blood / Q000473:pathology*; D006229:Hand Dermatoses / Q000097:blood / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood / Q000473:pathology*; D013577:Syndrome
D000974:Antibodies, Antinuclear; C046750:Jo-1 antibody