Oral health related quality of life is affected by disease activity in Behçet's disease.
OBJECTIVE
This study aimed to investigate oral and general health related quality of life (QoL) in patients with Behçet's Disease (BD) and to assess the performance of Turkish versions of oral health related quality questionnaires.


METHODS
Ninety-four BD patients, 24 patients with recurrent aphthous stomatitis (RAS), 113 healthy controls (HC) and 44 dental patients were investigated. QoL was assessed by oral health impact profile-14 (OHIP-14), oral health related quality of life (OHQoL) and short form-36 (SF-36) questionnaires.


RESULTS
OHQoL, OHIP-14 and SF-36 subscale scores were significantly worse in patients with BD compared with those in HC (P < 0.05). Both OHIP-14 and OHQoL scores were significantly worse in active patients compared with inactives in BD and RAS (P < 0.05). Scores of SF-36 Role physical, Role emotional and Vitality were also lower in active patients than in inactives in BD (P < 0.05). Scores of OHIP-14 and OHQoL were significantly worse in patients treated with colchicine compared with those treated with immunosuppressives (P < 0.05).


CONCLUSIONS
Both oral and general QoL was impaired in BD and associated with disease activity and treatment modalities. Translated Turkish versions of OHIP-14 and OHQoL were also observed to be valid and reliable questionnaires for further studies.
Mumcu
G
G
Department of Basic Health Science, Faculty of Health Education, Marmara University, Istanbul, Turkey. goncamumcu@marmara.edu.tr
Inanc
N
N
Ergun
T
T
Ikiz
K
K
Gunes
M
M
Islek
U
U
Yavuz
S
S
Sur
H
H
Atalay
T
T
Direskeneli
H
H
D000328:Adult; D001294:Attitude to Health; D001528:Behcet Syndrome / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D003078:Colchicine / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004644:Emotions; D005260:Female; D006304:Health Status; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009909:Oral Health; D011788:Quality of Life; D015203:Reproducibility of Results; D013281:Stomatitis, Aphthous / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology; D011795:Surveys and Questionnaires / Q000592:standards
D007166:Immunosuppressive Agents; D003078:Colchicine