A note on QTL detecting for censored traits.
Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".
Department of Statistics, Columbia University, New York, NY 10027, USA. yf2113@columbia.edu
Yixin
Y
Fang
D002874:Chromosome Mapping; D003198:Computer Simulation; D008957:Models, Genetic; D040641:Quantitative Trait Loci