Pasteurella multocida infection of a total knee arthroplasty after a "dog lick".
The patient we report here underwent a total knee arthroplasty (TKA) which got infected with P. multocida after her dog had licked a small wound at the third toe of the same foot. Despite a correct treatment comprising synovectomy and cleansing, and an active antibiotic treatment for 3 months, the patient was readmitted for persistent infection of the same knee 2 weeks after the end of the antibiotic treatment. Sampling during surgery allowed for the growth of a P. multocida isolate proven by a molecular method to be identical to the previously isolated strain. This recurrent P. multocida infection was treated by a two-step change of the TKA comprising a 2-month period of antibiotic treatment between the two surgical interventions.
Microbiology Department, Ambroise Paré Hospital, AP-HP, Faculté de Médecine Paris-Ile de France-Ouest, UVSQ, 9 Avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France. beate.heym@apr.ap-hop-paris.fr
B
B
Heym
F
F
Jouve
M
M
Lemoal
A
A
Veil-Picard
A
A
Lortat-Jacob
M H
MH
Nicolas-Chanoine
D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019645:Arthroplasty, Replacement, Knee; D002939:Ciprofloxacin / Q000627:therapeutic use; D004285:Dogs / Q000382:microbiology*; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D010326:Pasteurella Infections / Q000175:diagnosis / Q000628:therapy*; D016979:Pasteurella multocida / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000382:microbiology* / Q000628:therapy; D012008:Recurrence; D012086:Reoperation; D012293:Rifampin / Q000627:therapeutic use; D000074402:Synovectomy
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D000658:Amoxicillin; D004318:Doxycycline; D012293:Rifampin