Renal impairment: a risk factor for ischemic heart disease.
Chronic kidney disease has emerged as a public health problem of primary importance, mainly because of the high risk for coronary heart disease and other cardiovascular complications of this condition. Patients with end-stage renal disease are at a uniquely high risk for a severe form of the disease but most of the population burden generated by atherosclerotic complications derives from patients with moderate and severe degrees of kidney disease. A reduction in coronary heart disease and cardiovascular events as related to chronic kidney disease demands large-scale preventive measures targeting individuals with evidence of renal dysfunction, well before the end-stage renal disease phase.
Zoccali
Carmine
C
Department of Nephrology, Hypertension & Renal Transplantation, CNR-IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal, Italy. carmine.zoccali@tin.it
D003327:Coronary Disease / Q000188:drug therapy / Q000628:therapy; D005919:Glomerular Filtration Rate; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D017202:Myocardial Ischemia / Q000209:etiology* / Q000517:prevention & control; D009204:Myocardial Revascularization; D012307:Risk Factors