[Studies on the chemical constituents in root of Coleus forskohlii].
OBJECTIVE
To study the chemical constituents in root of Coleusforskohlii.


METHODS
The chemical constituents were isolated by column chromatography. The structures were elucidated on the basis of IR, MS, 1H-NMR, 13C-NMR and 2D-NMR experiments.


RESULTS
Six compounds were obtained and the structures were identified as 14-deoxycoleon U (1), demethylcryptojaponol (2), alpha-amyrin (3), betulic acid (4), alpha-cedrol (5) and beta-sitosterol (6).


CONCLUSIONS
Compounds 1 and 2 were isolated from the genus Coleus for the first time. Compounds 3 and 4 were isolated from C. forskohlii for the first time.
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, China.
Ling-ling
LL
Xu
Jie
J
Lu
Wei-jia
WJ
Li
Ling-yi
LY
Kong
D031330:Coleus / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D053978:Pentacyclic Triterpenes; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000094062:Betulinic Acid
C518169:14-deoxycoleon U; D004224:Diterpenes; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; D009828:Oleanolic Acid; C036380:beta-amyrin; D000094062:Betulinic Acid