Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit.
OBJECTIVE
Previous publications using nonconcurrent series of patients indicate improved survival for patients with hypoplastic left heart syndrome (HLHS) undergoing stage I palliation with a right ventricle to pulmonary artery conduit (NW-RVPA) vs. a modified Blalock-Taussig shunt (NW-BT). We compared postoperative outcomes in a concurrent series of patients with HLHS undergoing an NW-BT procedure vs. NW-RVPA procedure.


METHODS
Perioperative data from 66 consecutive patients who underwent NW-BT (n = 37) or NW-RVPA (n = 29) procedures were retrospectively analyzed.


METHODS
Cardiac intensive care unit in a tertiary pediatric hospital.


METHODS
Charts were reviewed for all patients with the diagnosis of HLHS undergoing the NW-BT or NW-RVPA procedure between January 2002 and December 2003.


RESULTS
Cardiopulmonary bypass time was longer in the NW-BT group than in the NW-RVPA group (152.5 +/- 52.0 vs. 134.5 +/- 36.1 mins; p = .04). Postoperative diastolic pressures were higher and the Pao2 to Fio2 ratio profiles were lower for the NW-RVPA group over the first 72 hrs. Time to sternal closure (2 [1-6] vs. 4 [2-41] days; p = .01), duration of mechanical ventilation (113 [49-386] vs. 136 [84-764] hrs; p = .01), time to establish enteral feeds (4 [2-8] vs. 5 [3-22] days; p = .01), length of intensive care unit stay (11 [7-55] vs. 15 [8-90] days; p = .04), and length of hospital stay (16 [11-67] vs. 27 [12-126] days; p = .01) were shorter in the NW-RVPA group. Postoperative mortality was not significantly different between the NW-RVPA group (7%) and NW-BT group (11%).


CONCLUSIONS
At an experienced institution with low stage I palliation mortality for HLHS, there were no differences in early morbidity and mortality between the NW-RVPA and NW-BT procedures. The primary advantage of the NW-RVPA procedure may be faster recovery following surgery and earlier discharge from the hospital.
Department of Cardiology, Children's Hospital, Boston, MA, USA.
Clifford L
CL
Cua
Ravi R
RR
Thiagarajan
Kimberlee
K
Gauvreau
Lillian
L
Lai
John M
JM
Costello
David L
DL
Wessel
Pedro J
PJ
Del Nido
John E
JE
Mayer
Jane W
JW
Newburger
Peter C
PC
Laussen
D000704:Analysis of Variance; D000714:Anastomosis, Surgical; D006348:Cardiac Surgical Procedures / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000601:surgery*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010166:Palliative Care / Q000379:methods*; D011183:Postoperative Complications; D011379:Prognosis; D011651:Pulmonary Artery / Q000601:surgery; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D016896:Treatment Outcome