Thermal expansion of blood vessels in low cryogenic temperatures Part I: A new experimental device.
As part of the ongoing effort to study the mechanical behavior of biological material during cryopreservation processes, the current study focuses on thermal expansion of blood vessels at low cryogenic temperatures. The current paper (Part I) describes a new experimental device for thermal expansion measurements of blood vessels in typical conditions of vitrification, which are associated with rapid cooling rates. For validation purposes, the thermal strain of frozen arteries in the absence of cryoprotectants was measured, and found to be about 10% larger than that of polycrystalline water; this observation agrees with literature data. The companion paper (Part II) reports on experimental results of cryoprotectants permeated with VS55, DP6, and 7.05 M DMSO at high cooling rates applicable to vitrification.
Jimenez Rios
Jorge L
JL
Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Rabin
Yoed
Y
D001808:Blood Vessels / Q000502:physiology*; D015925:Cryopreservation / Q000295:instrumentation* / Q000379:methods*; D003451:Cryoprotective Agents / Q000737:chemistry*; D004867:Equipment Design; D005615:Freezing; D006358:Hot Temperature; D009926:Organ Preservation; D013696:Temperature; D013997:Time Factors
D003451:Cryoprotective Agents