Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret.
A 2-year-old domestic ferret that appeared clinically healthy was repeatedly seropositive for Aleutian mink disease parvovirus (ADV) over a 2-year observation period. Antibody titers, determined by counter-immunoelectrophoresis, ranged from 1024 to 4096. Viral DNA also was identified in serum, urine, feces, and blood cell fractions by polymerase chain reaction analysis. Ultimately, DNA in situ hybridization revealed ADV DNA in histologic sections of various tissues and organs. These data indicate that this asymptomatic ferret was persistently infected with ADV.
Department of Pathology, University of Georgia College of Veterinary Medicine, Athens 30602, USA.
Kate E
KE
Pennick
Mary Ann M
MA
Stevenson
Kenneth S
KS
Latimer
Branson W
BW
Ritchie
Christopher R
CR
Gregory
D000453:Aleutian Mink Disease / Q000821:virology*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002353:Carrier State / Q000503:physiopathology / Q000821:virology*; D004279:DNA, Viral; D005289:Ferrets / Q000502:physiology / Q000821:virology*; D007668:Kidney / Q000821:virology; D008099:Liver / Q000821:virology; D008168:Lung / Q000821:virology; D008297:Male; D013154:Spleen / Q000821:virology; D014556:Urine / Q000821:virology; D017201:Virus Shedding
D000914:Antibodies, Viral; D004279:DNA, Viral