[Perianal Bowen's disease treated with imiquimod].
Bowen's disease is a special form of squamous cell carcinoma in situ that usually develops in photoexposed areas of skin. The treatment of choice is surgery. Less frequently, it may appear in other locations such as the nails, glans penis, intertriginous areas and the perianal region, where conventional treatment may be complicated. We contribute a new case of perianal Bowen's disease, which responded to treatment with imiquimod with no evidence of clinical recurrence after 3 years of follow up. Imiquimod appears to be a therapeutic alternative for perianal Bowen's disease, which seems to have a particular tendency to recur in this location where surgery may also be complicated.
Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, Spain.
Alberto
A
Alfaro-Rubio
Eduardo
E
Nagore
Carlos
C
Serra
Rafael
R
Botella
Onofre
O
Sanmartín
Celia
C
Requena
Beatriz
B
Llombart
Luis
L
Hueso
Carlos
C
Guillén
D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001005:Anus Neoplasms / Q000188:drug therapy*; D001913:Bowen's Disease / Q000188:drug therapy*; D006801:Humans; D000077271:Imiquimod; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy*
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod