Comparative study between preoperative and postoperative histologic grading in adenocarcinoma of the colon and rectum.
BACKGROUND
Preoperative histologic grading was used to decide the length of the margin of resection in adenocarcinoma of colon and rectum.


OBJECTIVE
The aim of the present study was to determine the accuracy of preoperative histologic grading by comparison with postoperative histologic grading.


METHODS
Preoperative and postoperative histologic grading of patients with adenocarcinoma of the colon and rectum in the department of surgery, Phramongkutklao Hospital between January 1999 and October 2004 were collected and compared together using percentage and chi-square test.


RESULTS
260 patients were included in the present study. 47.3% of all cases had inaccurate preoperative histologic grading. 43% of all cases had worse differentiation. 52.7% of all cases had the same differentiation. Only 4.3% of all cases had better differentiation.


CONCLUSIONS
Preoperative histologic grading was not accurate and could not be used in deciding the length of the margin of resection.
Division of Colorectal Surgery, Department of Surgery, Phramongkutklao Hospital, Bangkok 10400, Thailand. bunluec@yahoo.com
Bunlue
B
Chaleoykitti
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy; D003107:Colorectal Surgery / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging / Q000592:standards*; D011182:Postoperative Care / Q000592:standards*; D011300:Preoperative Care / Q000592:standards*; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery