Comment on point: counterpoint "in health and in a normoxic environment, VO2 max is/is not limited primarily by cardiac output and locomotor muscle blood flow". Vol 100: 744-8, 2006. The major factor limiting VO2 max in health and normoxia is oxygen transport to active muscles.
di Prampero
P E
PE
Capelli
C
C
Ferretti
G
G
D001692:Biological Transport / Q000502:physiology; D002302:Cardiac Output; D015444:Exercise; D006801:Humans; D008931:Mitochondria, Muscle / Q000201:enzymology / Q000502:physiology; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000502:physiology; D010100:Oxygen / Q000097:blood / Q000378:metabolism; D010101:Oxygen Consumption; D012039:Regional Blood Flow / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology
D010100:Oxygen