Health-related quality of life after polypectomy with and without additional surgery.
OBJECTIVE
The objective of this study was to compare the health-related quality of life of patients undergoing simple polypectomy with that of patients undergoing polypectomy with additional surgery.


METHODS
This was a prospective, multicenter cohort study of adults undergoing sinonasal surgery.


METHODS
Eight hundred forty-four patients received simple polypectomy and 1,004 patients received polypectomy with additional surgery. Health-related quality of life was compared at 12 and 36 months after surgery using the Sino-Nasal Outcome Test (SNOT-22). Total SNOT-22 scores may range from zero to 110 with lower scores representing better outcomes. We used linear regression to adjust postoperative SNOT-22 scores for baseline characteristics. When comparing the difference between the two surgical techniques, positive SNOT-22 scores represent a better outcome for those undergoing additional surgery.


RESULTS
There were only small differences between the two groups at 12 months (difference in SNOT-22 -0.5; 95% confidence interval [CI]=-2.3-1.3; P=.58) and 36 months after surgery (difference -2.1; 95% CI=-4.4-0.2; P=.08). The additional surgery group had a slightly higher risk of excessive perioperative bleeding (8.6% vs. 6.0%; P=.04) but a slightly lower risk of revision surgery within 36 months (10.4% vs. 13.3%; P=.12).


CONCLUSIONS
Nasal polypectomy with additional surgery seems to have no benefit over simple polypectomy in terms of health-related quality of life improvement for patients with nasal polyposis.
Browne
John Patrick
JP
Clinical Effectiveness Unit, Royal College of Surgeons of England, London, and the Royal United Hospital Bath, Bath, Somerset, United Kingdom. jbrowne@rcseng.ac.uk
Hopkins
Claire
C
Slack
Robert
R
Topham
John
J
Reeves
Barnaby
B
Lund
Valerie
V
Brown
Peter
P
Copley
Lynn
L
van der Meulen
Jan
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D009298:Nasal Polyps / Q000601:surgery*; D013517:Otorhinolaryngologic Surgical Procedures; D011446:Prospective Studies; D011788:Quality of Life; D016896:Treatment Outcome