Collagen and biphasic calcium phosphate bone graft in large osseous defects.
The cavity left by the removal of tumors represents a challenge for the orthopedic oncologic surgeon. This article takes a critical look at the use of a synthetic bone graft to fill the residual space. A combination of hydroxyapatite, tricalcium phosphate, and bovine collagen was used for intramedullary tumors. Thirty patients were followed for an average of 23 months. The majority (93%) returned to full activity with only 6 (20%) complications. Study results showed collagen and biphasic calcium phosphate ceramic bone graft makes an effective substrate for filling intramedullary cavities remaining after tumor excision.
Department of Orthopedic Surgery, Texas Tech University, Lubbock, Tex, USA.
Jerry Speight
JS
Grimes
Therese J
TJ
Bocklage
John David
JD
Pitcher
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D018786:Bone Substitutes; D016025:Bone Transplantation; D002130:Calcium Phosphates / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013977:Tibia / Q000601:surgery
D018786:Bone Substitutes; D002130:Calcium Phosphates; C065819:Collagraft; D003094:Collagen