Adult-onset Still's disease with prurigo pigmentosa-like skin eruption.
A 34-year-old woman with adult-onset Still's disease (AOSD) developed prurigo pigmentosa-like lesions on her chest and upper back in addition to the typical rash of AOSD. A biopsy specimen taken from the upper back showed characteristic features of prurigo pigmentosa. The eruption and fever subsided immediately after the administration of 40 mg/day prednisolone, but arthralgia persisted even after intravenous pulse methylprednisolone therapy in combination with immunosuppressive drugs. Various atypical skin rashes, including prurigo pigmentosa-like lesions, have been reported in association with AOSD. Therefore, one should carefully follow the clinical course of a patient in order not to overlook these atypical cutaneous manifestations of AOSD.
Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan. qqwz56kh9@arion.ocn.ne.jp
Kahori
K
Tomaru
Yayoi
Y
Nagai
Naoko
N
Ohyama
Michiko
M
Hasegawa
Yukie
Y
Endo
Atsushi
A
Tamura
Osamu
O
Ishikawa
D000328:Adult; D001415:Back / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology* / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage; D011536:Prurigo / Q000209:etiology* / Q000473:pathology; D016706:Still's Disease, Adult-Onset / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013909:Thorax / Q000473:pathology
D011239:Prednisolone