Dietary treatment of diabetes mellitus in the pre-insulin era (1914-1922).
Before the discovery of insulin, one of the most common dietary treatments of diabetes mellitus was a high-fat, low-carbohydrate diet. A review of Frederick M. Allen's case histories shows that a 70% fat, 8% carbohydrate diet could eliminate glycosuria among hospitalized patients. A reconsideration of the role of the high-fat, low-carbohydrate diet for the treatment of diabetes mellitus is in order.
Westman
Eric C
EC
Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA. ewestman@duke.edu
Yancy
William S
WS
Humphreys
Margaret
M
D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy / Q000266:history*; D003927:Diet, Diabetic / Q000266:history*; D049673:History, 20th Century; D006801:Humans; D007004:Hypoglycemic Agents / Q000266:history / Q000627:therapeutic use; D007328:Insulin / Q000266:history / Q000627:therapeutic use
D007004:Hypoglycemic Agents; D007328:Insulin