Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infection.
We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples showed high titers against the heterologous virus.
Universidad del Desarrollo, Santiago, Chile.
Francisca
F
Valdivieso
Pablo
P
Vial
Marcela
M
Ferres
Chunyan
C
Ye
Diane
D
Goade
Analia
A
Cuiza
Brian
B
Hjelle
D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D002677:Chile / Q000453:epidemiology; D006476:Orthohantavirus / Q000276:immunology*; D018804:Hantavirus Pulmonary Syndrome / Q000097:blood / Q000453:epidemiology / Q000276:immunology* / Q000821:virology; D006801:Humans; D009500:Neutralization Tests; D029261:Sin Nombre virus / Q000276:immunology*; D017741:Survivors; D014481:United States / Q000453:epidemiology
D000914:Antibodies, Viral