Ethnic differences in the distribution of interleukin-6 polymorphisms among three Brazilian ethnic groups.
Polymorphisms in the interleukin-6 promoter region have been associated with diseases. In this study we investigated the -634G/C and -174G/C IL-6 promoter polymorphisms in three Brazilian ethnic groups. We verified that the allele frequencies of the two polymorphisms and haplotype frequencies varied significantly between the populations.
Gadelha
S R
SR
Laboratório Avançado de Saúde Pública, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, rua Waldemar Falcão 121, Salvador, Brazil.
Alcantara
L C
LC
Costa
G C S
GC
Rios
D L
DL
Galvão-Castro
B
B
D001938:Brazil; D016009:Chi-Square Distribution; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics*; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics
D015850:Interleukin-6