Normal macular thickness measurements in healthy eyes using Stratus optical coherence tomography.
OBJECTIVE
To report normal macular thickness measurements in healthy eyes using the latest commercially available optical coherence tomography (OCT) mapping software, version 3.0, from the Stratus OCT (OCT3).


METHODS
Thirty-seven eyes from 37 healthy subjects underwent a complete ophthalmologic examination, including OCT. Six radial scans, 6 mm in length and centered on the fovea, were obtained using the OCT3. Retinal thickness was automatically calculated by OCT mapping software. Measurements were displayed as the mean and standard deviation for each of the 9 regions defined in the Early Treatment Diabetic Retinopathy Study.


RESULTS
Foveal thickness (mean thickness in the central 1000-microm diameter area) and central foveal thickness (mean thickness at the point of intersection of 6 radial scans) on the OCT3 were 212 +/- 20 and 182 +/- 23 microm, respectively. Macular thickness measurements were thinnest at the center of the fovea, thickest within 3-mm diameter of the center, and diminished toward the periphery of the macula. The temporal quadrant was thinner than the nasal quadrant. Central foveal thickness was also manually determined as 170 +/- 18 microm, approximately 12 microm less than the value automatically obtained from the OCT3 software. There was no correlation between age and foveal thickness (P = .80).


CONCLUSIONS
Mean foveal thickness measurements were 38 to 62 microm thicker than previously reported values, while mean central foveal thickness measurements were 20 to 49 microm thicker than previously published values. This discrepancy should be considered when interpreting OCT scans.
Chan
Annie
A
New England Eye Center, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Mass 02111-1533, USA.
Duker
Jay S
JS
Ko
Tony H
TH
Fujimoto
James G
JG
Schuman
Joel S
JS
D000328:Adult; D000368:Aged; D001837:Body Weights and Measures; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D041623:Tomography, Optical Coherence / Q000379:methods*