Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives.
Synthesis of twelve Sansalvamide A derivatives and their SAR against colon cancer (HT-29).
Department of Chemistry and Biochemistry, San Diego State University, CA 92182-1030, USA.
Katerina
K
Otrubova
Thomas J
TJ
Styers
Po-Shen
PS
Pan
Rodrigo
R
Rodriguez
Kathleen L
KL
McGuire
Shelli R
SR
McAlpine
D000596:Amino Acids / Q000737:chemistry; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D003110:Colonic Neoplasms / Q000378:metabolism / Q000473:pathology; D047630:Depsipeptides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D000596:Amino Acids; D047630:Depsipeptides; C119376:sansalvamide A