A deuterated deep-cavity cavitand confirms the importance of C-H...X-R hydrogen bonds in guest binding.
A deuterated cavitand host was examined for its affinity to a series of guests; for halogenated, preorganized guests binding was significantly stronger than the corresponding protium host.
Laughrey
Zachary R
ZR
Department of Chemistry, University of New Orleans, New Orleans, LA 70148, USA.
Upton
Thomas G
TG
Gibb
Bruce C
BC