[Matched case-control study for risk factors of human Streptococcus suis infection in Sichuan Province, China].
OBJECTIVE
To study the potential risk factors of human infecting with Streptococcus suis.


METHODS
1: M matched case-control study was conducted. 29 human cases of Streptococcus suis infection in the early phase were included in the case group, Patients' family members, neighbors and peoples who had worked together with patients to handle deceased or sick pigs in the last week were recruited as matched controls. There were 147 controls in total. Both cases and controls received questionnaire investigation including the ways to contact sick/dead pigs. Conditional logistic regression was employed to analyze matching data.


RESULTS
According to the results of multivariate analysis, slaughtering (OR = 11.978, 95% CI: 3.355-42.756), carcasses cutting and processing (OR = 3.008, 95% CI: 1.022-8.849) sick/dead pigs were associated with cases related to human Streptococcus suis infection. The attributable risk proportion were 91.65% and 66.76% respectively. The other types of exposures to sick/ dead pigs, including feeding, selling, burying and eating, were not associated with the human Streptococcus suis infection in our study population.


CONCLUSIONS
Slaughtering, carcasses cutting and processing sick/dead pigs were important risky behavior for humans to be infected by Streptococcus suis.
Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Hong-jie
HJ
Yu
Xue-cheng
XC
Liu
Shi-wen
SW
Wang
Lun-guang
LG
Liu
Rong-qiang
RQ
Zu
Wen-jun
WJ
Zhong
Xiao-ping
XP
Zhu
Ni-juan
NJ
Xiang
Heng
H
Yuan
Ling
L
Meng
Yang-bing
YB
Ou
Yong-jun
YJ
Gao
Qiang
Q
Lv
Yan
Y
Huang
Xiang-dong
XD
An
Ting
T
Huang
Xing-yu
XY
Zhou
Liao
L
Feng
Qi-di
QD
Pang
Wei-zhong
WZ
Yang
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016273:Occupational Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D012307:Risk Factors; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000209:etiology / Q000382:microbiology*; D017011:Streptococcus suis / Q000502:physiology*