Effects in fat.
Biological actions in adipocytes can be mediated directly via circulating hormones or indirectly via sympathetic innervation of fat. Direct effects can be usefully assessed in preparations in which adipocytes have been dissociated from each other, and are therefore directly exposed to substrate and hormones. Amylin appears to have no direct effects in isolated adipocytes.
Young
Andrew
A
Amylin Pharmaceuticals, Inc., San Diego, California, USA.
D017667:Adipocytes / Q000187:drug effects* / Q000378:metabolism; D000682:Amyloid / Q000494:pharmacology*; D000818:Animals; D005990:Glycerol / Q000378:metabolism; D006801:Humans; D058228:Islet Amyloid Polypeptide
D000682:Amyloid; D058228:Islet Amyloid Polypeptide; D005990:Glycerol