[Sub-Tenon's injection of triamcinolone acetonide for choroidal neovascularization].
OBJECTIVE
To evaluate the efficacy of sub-Tenon's injection of triamcinolone acetonide for age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).


METHODS
Sub-Tenon's injection of triamcinolone acetonide was performed in patients (27 eyes) with the subfoveal choroidal neovascularization of AMD and in patients (10 eyes) with PCV, and its efficacy was evaluated. The visual acuity and the exudation from lesions evaluated by fluorescein angiography or optical coherence tomography (OCT) at three months or six months after injection were compared to the baseline values.


RESULTS
Visual acuity was maintained in 23 of the 27 eyes (85.0%) with AMD and in 8 of the 10 eyes (80.0%) with PCV at three months after injection. Six months after infusion, the rate declined to 76.0% and 66.7%, respectively. Exudation from lesions had decreased in 10 eyes of 25 eyes(40.0%) with AMD and in 2 eyes of 9 eyes (22.2%) with PCV by six months after injection. Complete suppression of the lesions was observed in seven eyes (18.9%) with relatively small lesions.


CONCLUSIONS
Sub-Tenon's injection of triamcinolone acetonide is useful as a treatment modality for AMD and PCV.
Department of Ophthalmology, Osaka University Hospital, Suita, Japan. aya.kimu@mhc.west.ntt.co.jp
Aya
A
Kim
Fumi
F
Gomi
Hirokazu
H
Sakaguchi
Yusuke
Y
Oshima
Yasushi
Y
Ikuno
Motohiro
M
Kamei
Masahito
M
Oji
Yasuo
Y
Tano
D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014792:Visual Acuity
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide