Triphenylphosphine as a ligand for room-temperature Ni(0)-catalyzed cross-coupling reactions of aryl chlorides with arylboronic acids.
Room-temperature Ni(0)-catalyzed cross-coupling reactions of deactivated aryl chlorides with arylboronic acids with inexpensive triphenylphosphine (PPh3) as a supporting ligand have been accomplished in good to excellent yields. Air-stable Ni(PPh3)2Cl2 has also been established as catalyst precursor, and highly active nickel catalysts were obtained when the reduction of Ni(PPh3)2Cl2 with n-BuLi was carried out in the presence of an aryl chloride.
Tang
Zhen-Yu
ZY
Department of Chemistry, College of Staten Island and Graduate Center of the City University of New York, Staten Island, New York 10314, USA.
Hu
Qiao-Sheng
QS
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D008024:Ligands; D009532:Nickel / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013696:Temperature
D001897:Boronic Acids; D002712:Chlorides; D008024:Ligands; D009943:Organophosphorus Compounds; C061896:triphenylphosphine; D009532:Nickel