Periocular microcystic adnexal carcinoma: management and outcome with Mohs' micrographic surgery.
OBJECTIVE
To report a series of patients with periocular microcystic adnexal carcinoma (MAC) treated with Mohs' micrographic surgery (MMS).


METHODS
Prospective, interventional case series.


METHODS
This series included all patients treated with MMS for periocular MAC, who were monitored by the Skin and Cancer Foundation Australia between 1993 and 2002.


RESULTS
There were 5 patients (4 males, 1 female) with a mean age of 52 +/- 12 years. Four tumors were located in the medial canthus and one in the lower lid. The tumor was initially misdiagnosed as basal cell carcinoma in 3 patients and squamous cell carcinoma in 1 patient. The average number of excision levels required for complete removal of the tumor during MMS was 2.2 (range 1-6). Perineural invasion was recorded in one patient.Five-year follow-up data was available for 3 patients, and there was no tumor recurrence in any of these cases.


CONCLUSIONS
The low 5-year recurrence rate of periocular MAC with MMS emphasizes the importance of margin-controlled excision of this tumor.
Oculoplastic and Orbital Unit, Department of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.
Igal
I
Leibovitch
Shyamala C
SC
Huilgol
Shawn
S
Richards
Robert
R
Paver
Dinesh
D
Selva
D018280:Carcinoma, Skin Appendage / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery / Q000379:methods*; D011446:Prospective Studies; D016896:Treatment Outcome