Fatal postoperative pulmonary embolism in mild haemophilia.
The use of thromboprophylaxis in patients with haemophilia receiving factor replacement is often not considered necessary, but remains an area of debate. In this report we describe a patient with mild haemophilia A, who underwent major pelvic surgery. He had several underlying risk factors associated with the development of thromboembolism, and ultimately died as a direct consequence of multiple pulmonary emboli. The need for thromboprophylaxis and the risk balance ratio should always be considered in patients with bleeding disorders if they fall into what would otherwise be high-risk category for hospital acquired venous thromboembolism.
Butcher
J H
JH
Department of Haematology, Bart's and The London, Queen Mary's School of Medicine and Dentistry, London, UK.
Pasi
K J
KJ
D000368:Aged; D015179:Colorectal Neoplasms / Q000601:surgery; D017809:Fatal Outcome; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D011655:Pulmonary Embolism / Q000209:etiology* / Q000517:prevention & control; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control