Vascular and Alzheimer-type pathology in an autopsy study of African-Americans.
The authors studied 13 autopsy brains from a larger cohort of 270 African-Americans with a clinical diagnosis of Alzheimer disease (AD), vascular dementia (VaD), or stroke without dementia. Two subjects exhibited changes of pure VaD, 5 had pure AD, and 6 showed a mixture of AD pathology and strokes. Overall, there was good agreement between the pathologic diagnoses and the clinical diagnoses.
Pytel
P
P
Department of Pathology, The University of Chicago, IL, USA. peter.pytel@uchospitals.edu
Cochran
E J
EJ
Bonner
G
G
Nyenhuis
D L
DL
Thomas
C
C
Gorelick
P B
PB
D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000208:ethnology / Q000473:pathology*; D001344:Autopsy; D001921:Brain / Q000473:pathology*; D002544:Cerebral Infarction / Q000208:ethnology / Q000473:pathology*; D015140:Dementia, Vascular / Q000208:ethnology / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D016037:Single-Blind Method