Bone morphogenic protein science and studies.
The use of growth factors, such as bone morphogenic proteins (BMPs), is showing great promise in orthopaedic surgery. The BMPs, which are osteoinductive, have been used successfully in spine fusion and fracture healing. This article describes the development and production of the recombinant BMPs and summarizes their use in preclinical trials.
Hospital for Special Surgery, New York, NY 10021, USA. lanej@hss.edu
Joseph M
JM
Lane
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000502:physiology* / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D005264:Femoral Fractures / Q000601:surgery / Q000628:therapy*; D017102:Fracture Healing / Q000502:physiology*; D006133:Growth Substances / Q000627:therapeutic use*; D006801:Humans
D019485:Bone Morphogenetic Proteins; D006133:Growth Substances