Triphenylphosphine as a ligand for room-temperature Ni(0)-catalyzed cross-coupling reactions of aryl chlorides with arylboronic acids.
Room-temperature Ni(0)-catalyzed cross-coupling reactions of deactivated aryl chlorides with arylboronic acids with inexpensive triphenylphosphine (PPh3) as a supporting ligand have been accomplished in good to excellent yields. Air-stable Ni(PPh3)2Cl2 has also been established as catalyst precursor, and highly active nickel catalysts were obtained when the reduction of Ni(PPh3)2Cl2 with n-BuLi was carried out in the presence of an aryl chloride.
Department of Chemistry, College of Staten Island and Graduate Center of the City University of New York, Staten Island, New York 10314, USA.
Zhen-Yu
ZY
Tang
Qiao-Sheng
QS
Hu
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D008024:Ligands; D009532:Nickel / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013696:Temperature
D001897:Boronic Acids; D002712:Chlorides; D008024:Ligands; D009943:Organophosphorus Compounds; C061896:triphenylphosphine; D009532:Nickel