[Long-term survival rate of patients transfused with leucocyte-depleted and buffy-coat-poor blood during colorectal surgery--secondary publication. An eight-year post-trial follow-up study].
This study investigated the long-term survival rate of 589 patients enrolled in a trial in 1992-1995 who underwent colorectal surgery. The patients were randomised to receive leucocyte-depleted or buffy-coat-poor blood when transfusion was indicated. Significantly more of the non-transfused patients (59%) were alive seven years later compared to patients transfused with leucocyte-depleted blood (41%) and to patients transfused with buffy-coat-poor blood (45%).
Arhus Universitetshospital, Arhus Sygehus, Kirurgisk-gastroenterologisk Afdeling L. lsjen@as.aaa.dk
Lone S
LS
Jensen
Erzsebet
E
Puho
Lars
L
Pedersen
Frank V
FV
Mortensen
Henrik Toft
HT
Sørensen
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000401:mortality; D001781:Blood Component Removal; D015179:Colorectal Neoplasms / Q000401:mortality / Q000601:surgery*; D017707:Erythrocyte Transfusion; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D047589:Leukocyte Reduction Procedures; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality*; D016032:Randomized Controlled Trials as Topic; D015996:Survival Rate