Ethnic differences in the distribution of interleukin-6 polymorphisms among three Brazilian ethnic groups.
Polymorphisms in the interleukin-6 promoter region have been associated with diseases. In this study we investigated the -634G/C and -174G/C IL-6 promoter polymorphisms in three Brazilian ethnic groups. We verified that the allele frequencies of the two polymorphisms and haplotype frequencies varied significantly between the populations.
Laboratório Avançado de Saúde Pública, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, rua Waldemar Falcão 121, Salvador, Brazil.
S R
SR
Gadelha
L C
LC
Alcantara
G C S
GC
Costa
D L
DL
Rios
B
B
Galvão-Castro
D001938:Brazil; D016009:Chi-Square Distribution; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics*; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics
D015850:Interleukin-6