Microalbuminuria prevalence study (MAPS) in hypertensive patients with type 2 diabetes in Thailand.
BACKGROUND
Microalbuminuria represents the earliest clinical evidence of diabetic nephropathy, and is a marker of increased cardiovascular (CV) morbidity and mortality.


OBJECTIVE
This analysis of Thai data from the Microalbuminuria Prevalence Study (MAPS) assessed the prevalence of macroalbuminuria and microalbuminuria in hypertensive patients with type 2 diabetes.


METHODS
Cross-sectional clinic-based epidemiological study.


METHODS
A total of 100 patients were enrolled, of which 97 patients constituted the per-protocol population (patients with bacteriuria and haematuria were excluded). Patients attended one study visit with no follow-up.


RESULTS
Overall, the prevalence of diabetic kidney disease was high, with macroalbuminuria contributing 13.4% [9.9-16.9; 95% confidence interval (CI)] and microalbuminuria contributing 43.3% [38.3-48.3; 95%CI].


CONCLUSIONS
Annual screening for microalbuminuria is recommended for all patients with type 2 diabetes, as early treatment is critical for reducing CV risks. Clinical studies have shown that renin-angiotensin system inhibitors can slow the progression of diabetic nephropathy.
Division of Hypertension, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Prannok Rd, Bangkoknoi, Bangkok 10700, Thailand. sipbn@mahidol.ac.th
Peera
P
Buranakitjaroen
Chaicharn
C
Deerochanawong
Pongamorn
P
Bunnag
D000419:Albuminuria / Q000175:diagnosis* / Q000453:epidemiology / Q000652:urine; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000652:urine*; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000453:epidemiology / Q000652:urine*; D018450:Disease Progression; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000652:urine*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012084:Renin-Angiotensin System; D013785:Thailand / Q000453:epidemiology; D013997:Time Factors