[Research progress of targeting and translocation of proteins mediated by signal recognition particle in prokaryote].
How proteins are targeted and translocated mediated by signal recognition particle (SRP) in eukaryotic cell is very clear and uniform. In contrast, SRP systems are different in various kinds of prokaryotic cells, So it is difficult to identify. Nowadays, the studies of prokaryotic SRP system focus on the structure and function of Ffh, FtsY, 4.5S RNA, and GTP as a regulating molecular. Here, a description was given on research progress of constitutes, structures and functions of bacterial SRP complex proteins. The research status of streptomyces SRP pathway was also reviewed, and this study in streptomyces will be helpful to explain the molecular mechanism of prokaryotic SRP system.
Zheng
Jing
J
College of Life Science, Zhejiang University, Hangzhou 310027, China.
Dong
Hui-Jun
HJ
Wang
Chun-Xia
CX
Guan
Wen-Jun
WJ
Li
Yong-Quan
YQ
D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology; D006160:Guanosine Triphosphate / Q000502:physiology; D021381:Protein Transport; D012329:RNA, Bacterial / Q000737:chemistry / Q000502:physiology; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry / Q000502:physiology; D018271:Signal Recognition Particle / Q000502:physiology*; D013302:Streptomyces / Q000378:metabolism*
C409968:4.5S RNA; D001426:Bacterial Proteins; C087406:FtsY protein, Bacteria; D012329:RNA, Bacterial; D018160:Receptors, Cytoplasmic and Nuclear; D018271:Signal Recognition Particle; D006160:Guanosine Triphosphate