[Event-related EEG and evoked potential investigations in clinical practice].
Considering the limits of the traditional EEG techniques the authors review the main methods and clinical importance of the event-related EEG investigations. According to methods, these can be classified into the spectral analysis of task-related, pre-task and post-task recordings as well as stimulus-controlled measurements based on evoked potential techniques. The main results of clinical studies on the event-related EEG methods are summarized according to chief disease groups (Alzheimer's disease, epilepsy, schizophrenia, Parkinson's disease, dyslexia, depression). The authors discuss the stimulus-dependent EEG discharges (P300, cognitive potential) in detail. They present the meta-analysis of 224 recent publications on human application of these methods. They analyze the involved scientific areas and the frequency by which these methods were applied in each. Following this, the results of 83 selected clinical studies are summarized. The frequency of the application of the various event-related EEG methods and the tested wave components and other parameters are listed. Finally a summary of the main clinical results is presented again by groups of diseases (schizophrenia, behavioral disorders, traumatic lesions, enuresis nocturna, depression, memory disturbance and dementia, drug effect). Finally, the potential perspectives and the limitations of the event-related EEG methods are briefly discussed.
Rajna
Péter
P
Semmelweis Egyetem, Altalános Orvostudományi Kar, Pszichiátriai es Pszichoterápiás Klinika, Budapest. rajna@psych.sote.hu
Hidasi
Zoltán
Z
Waldemar
Szelenberger
S
D000544:Alzheimer Disease / Q000503:physiopathology; D003863:Depression / Q000503:physiopathology; D004410:Dyslexia / Q000503:physiopathology; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology; D018913:Event-Related Potentials, P300; D005071:Evoked Potentials; D006801:Humans; D010300:Parkinson Disease / Q000503:physiopathology; D012559:Schizophrenia / Q000503:physiopathology