[Influence of enteroviruses on metabolism of fatty acids in human embryo fibroblasts].
The investigations on changes in metabolism of lipids--saturated and nonsaturated fatty acids in membranes of fibroblasts of the human embryo on a background of Coxsackie B virus infection have been done. Virus-induced changes of the lipid composition are indicated by a higher level of content of eicosatrienic and arachidonic PNFA, and a sum of nonsaturated and polynon saturated fatty acids. Such phenomena (most expressed for serotypes of Coxsackie B2, B3, B4 viruses) promote the increase of permeability of biological membranes and infiltration of viruses into the cell.
Shyrobokov
V P
VP
Ievtushenko
O I
OI
Krotenko
O V
OV
Briuzhina
T S
TS
D002462:Cell Membrane / Q000378:metabolism* / Q000821:virology; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral; D004622:Embryo, Mammalian; D029822:Enterovirus B, Human / Q000472:pathogenicity*; D005227:Fatty Acids / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism* / Q000821:virology; D006801:Humans
D005227:Fatty Acids