[Late effects after chemotherapy].
Today, about 60% of adult patients and 80% children diagnosed with cancer will survive 5 years after diagnosis. Approximately two thirds of cancer survivors will experience at least one late effect, and about one third severe or life threatening late effects. The aim of cancer treatment today is to cure the malignant disease but at the same time, to minimize the incidence of post-treatment complications. In the current overview we summarize, based on the most recent publications, typical late effects in cancer survivors.
Abteilung Hämatolgie/Onkologie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Leipzig AöR, Leipzig. nied@medizin.uni-leipzig.de
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D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D009202:Cardiomyopathies / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D009369:Neoplasms / Q000188:drug therapy* / Q000401:mortality; D009395:Nephritis, Interstitial / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D009422:Nervous System Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D011658:Pulmonary Fibrosis / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D015996:Survival Rate
D000970:Antineoplastic Agents