Platelet interactions with vessel wall components during thrombogenesis.
We discuss the interrelationships of platelet glycoprotein receptors, von Willebrand factor, collagen, non-collagen matrix protein, and vascular cells in the complex events of platelet plug and subsequent thrombus formation.
Ruggeri
Zaverio M
ZM
Roon Center for Arteriosclerosis and Thrombosis, Division of Experimental Hemostasis and Thrombosis, Department of Molecular and Experimental Medicine, The Scripps Research Institute-MEM 175, La Jolla, CA 92037, USA. ruggeri@scripps.edu
D000818:Animals; D004730:Endothelium, Vascular / Q000473:pathology*; D016326:Extracellular Matrix Proteins; D006801:Humans; D010973:Platelet Adhesiveness; D011956:Receptors, Cell Surface; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology; D014841:von Willebrand Factor
D016326:Extracellular Matrix Proteins; D011956:Receptors, Cell Surface; D014841:von Willebrand Factor