[A case of recurrent gastric cancer with improvement of obstructive symptoms caused by carcinomatous peritonitis and prolonged survival by chemotherapy with combined use of Paclitaxel and 5-FU].
A 29-year-old male underwent Cur B surgery including total gastrectomy, pancreaticoduodenectomy, transverse colectomy, and D 2 dissection for scirrhous gastric carcinoma accompanied by duodenal and pancreatic infiltration. Thereafter, the patient suffered from recurrence with development of ileus caused by carcinomatous peritonitis. Ileus tube was inserted, followed by conservative therapy without ingestion. But, as the symptoms aggravated without any alleviation, an emergency surgical procedure was conducted. As disseminated changes were observed in the entire region of the abdominal cavity of the epigastric region, ileus by-pass procedure and ileostomy were performed. Though ileus symptoms were improved, peroral intake was difficult,and the ileus tube had to be left in place. Thereafter, chemotherapy with combined use of paclitaxel and 5-FU was initiated, and peroral intake become possible. The Ileus tube could be removed after improvement of obstructive symptoms. The patient was treated at the outpatient clinic with nutritional help of HPN, but died 14 months after the recurrence.
Dept. of Surgery, Hiroshima City Hospital.
Takahiro
T
Mimae
Motoki
M
Ninomiya
Hiroshi
H
Sasaki
Youji
Y
Kubo
Tohru
T
Kojima
Tatsuo
T
Umeoka
Norihisa
N
Takakura
D002293:Adenocarcinoma, Scirrhous / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006801:Humans; D045823:Ileus / Q000209:etiology* / Q000601:surgery; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D017239:Paclitaxel / Q000008:administration & dosage; D016577:Pancreaticoduodenectomy; D016562:Parenteral Nutrition, Home Total; D010538:Peritonitis / Q000628:therapy*; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000601:surgery
D017239:Paclitaxel; D005472:Fluorouracil