Traumatic intracranial hemorrhage in patients with seizures: descriptive characteristics.
We reviewed the records of all patients with recurrent seizures and severe head injury-induced traumatic intracranial hemorrhage (TIH) between 1989 and 2003 in three Israeli medical centers. We identified 52 cases (44 males, mean age=43+/-19 years, range=8-84; 8 females; mean age=74+/-12 years, range=48-85). Twenty-seven (52%) had additional known risk factors for TIH, e.g., older age, alcohol abuse, and anticoagulant use. All five children and adolescents had mental retardation. Approximately one-half of patients with seizures and TIH have additional risk factors for TIH. Non-mentally retarded children and adolescents with seizures are probably at low risk of developing TIH. Women less than 70 years old with seizures are much less prone to TIH than men. In young "otherwise healthy" patients with epilepsy, suboptimal treatment seems to be an important factor in the occurrence of TIH.
Medvdovsky
Mordekhay
M
EEG and Epilepsy Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Ifergane
Gal
G
Wirguin
Itzhak
I
Vander
Tatiana
T
Dori
Amir
A
Kipervasser
Svetlana
S
Shifrin
Alla
A
Vakhapova-Danicek
Veronica
V
Neufeld
Miri Y
MY
D000058:Accidental Falls; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000435:Alcoholic Intoxication / Q000150:complications; D000925:Anticoagulants / Q000009:adverse effects; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D020198:Intracranial Hemorrhage, Traumatic / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D012640:Seizures / Q000150:complications*
D000925:Anticoagulants; D000927:Anticonvulsants