Neurobiological correlates of autism: a review of recent research.
This review paper integrates recent structural and functional imaging, postmortem, animal lesion, and neurochemical research about the pathophysiology of autism. An understanding of the neurobiological correlates of autism is becoming increasingly important as more children are diagnosed with the condition and funding for well-targeted interventions increases. Converging evidence suggests that autism involves abnormalities in brain volume, neurotransmitter systems, and neuronal growth. In addition, evidence firmly links autism with abnormalities in the cerebellum, the medial temporal lobe, and the frontal lobe. Potential implications of these findings and suggestions for future research are reviewed.
Penn
Helen E
HE
Clinical-Developmental Psychology Program, York University, Toronto, Ontario M3J IP3, Canada. hpenn@yorku.ca
D001321:Autistic Disorder / Q000503:physiopathology*; D001921:Brain / Q000002:abnormalities* / Q000378:metabolism; D002531:Cerebellum / Q000002:abnormalities / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D018377:Neurotransmitter Agents / Q000378:metabolism; D049268:Positron-Emission Tomography
D018377:Neurotransmitter Agents