Clostridium difficile-associated disease: new challenges from an established pathogen.
Clostridium difficile-associated disease (CDAD) can range from uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing, possibly due to a new strain. Transmission of C difficile occurs primarily in health care facilities via the fecal-oral route following transient contamination of the hands of health care workers and patients; contamination of the patient care environment also plays an important role.
Division of Healthcare Quality Promotion, US Centers for Disease Control and Prevention, USA.
Rebecca H
RH
Sunenshine
L Clifford
LC
McDonald
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use; D016360:Clostridioides difficile / Q000302:isolation & purification / Q000472:pathogenicity*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000188:drug therapy* / Q000517:prevention & control; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy* / Q000517:prevention & control; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D017053:Infection Control / Q000379:methods; D012307:Risk Factors
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents