A novel type of receptor cDNA from the prothoracic glands of the silkworm, Bombyx mori.
A cDNA encoding a novel heptahelical receptor from the prothoracic glands of the silkworm, Bombyx mori was cloned and sequenced during screening of a prothoracicotropic hormone (PTTH) receptor. Orthologs of this receptor are found not only in insects, but also in the vertebrates. In B. mori, ubiquitous expression of the mRNA was observed in the larva. Also, a higher expression level in the prothoracic glands was observed before molting and metamorphosis and was impaired after pupal molting. But, further analysis is required to confirm whether this receptor cDNA encodes the PTTH receptor.
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
Shinji
S
Nagata
Toshiki
T
Namiki
Rinkei
R
Ko
Hiroshi
H
Kataoka
Akinori
A
Suzuki
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D012831:Bombyx / Q000033:anatomy & histology* / Q000235:genetics*; D019556:COS Cells; D002522:Chlorocebus aethiops; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics*; D005786:Gene Expression Regulation; D006801:Humans; D007301:Insect Hormones / Q000378:metabolism*; D008969:Molecular Sequence Data; D010802:Phylogeny
D018076:DNA, Complementary; D007301:Insect Hormones; C009089:prothoracicotropic hormone