Rotavirus and severe childhood diarrhea.
Studies published between 1986 and 1999 indicated that rotavirus causes approximately 22% (range 17%-28%) of childhood diarrhea hospitalizations. From 2000 to 2004, this proportion increased to 39% (range 29%-45%). Application of this proportion to the recent World Health Organization estimates of diarrhea-related childhood deaths gave an estimated 611,000 (range 454,000-705,000) rotavirus-related deaths.
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. uap2@cdc.gov
Umesh D
UD
Parashar
Christopher J
CJ
Gibson
Joseph S
JS
Bresee
Roger I
RI
Glass
D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology / Q000821:virology; D014943:Global Health; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012401:Rotavirus; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology / Q000821:virology; D012720:Severity of Illness Index; D012923:Social Class