Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers.
A library of novel amphiphilic, self-assembling dendrimers was designed and synthesised to evaluate the effects of structural changes on transfection efficiency.
Guillot
Marine
M
Laboratorium für Organische Chemie, ETH-Zürich, 8093 Zürich, Switzerland.
Eisler
Sara
S
Weller
Kathrin
K
Merkle
Hans P
HP
Gallani
Jean-Louis
JL
Diederich
François
F
D050091:Dendrimers; D005822:Genetic Vectors / Q000737:chemistry* / Q000235:genetics; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D008081:Liposomes / Q000737:chemistry; D011073:Polyamines / Q000737:chemistry; D013329:Structure-Activity Relationship; D014162:Transfection / Q000379:methods*
D050091:Dendrimers; D008081:Liposomes; C104700:PAMAM Starburst; D011073:Polyamines; D049452:Green Fluorescent Proteins