Surgical and radiotherapy treatment of a spinal cord ependymoma in a dog.
A 4-year-old Beagle dog was presented for investigation of a left pelvic limb gait abnormality. Neurolocalisation indicated a lumbar (L2 to L5) spinal cord lesion. On magnetic resonance imaging (MRI), an intramedullary mass was demonstrated at L3. The mass was partially removed under general anaesthesia and a diagnosis of ependymoma was made on histological examination. The dog was treated with postoperative orthovoltage x-ray radiation (total dose; 44 Gy given in 11 fractions over a 4 week period) combined with low dose carboplatin (25 mg/m2). The dog was alive 16 months after surgery without further neurological deficits. No further tumour growth was detected on subsequent MRI evaluations.
Ueno
H
H
Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan. uehiro@cc.gifu-u.ac.jp
Morimoto
M
M
Kobayashi
Y
Y
Hizume
T
T
Murayama
N
N
Uzuka
Y
Y
D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D004285:Dogs; D004806:Ependymoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome