[Case report: mast cell leukosis in a neonatal calf].
Multicentric mast cell tumours in a newborn Fleckvieh-calf are described. The calf showed clearly pronounced lesions over the whole body. The lesions were multiple raised, cutaneous, greyisch-red and partially ulcerated. It died three hours after birth. Pathohistological examinations resulted in multiple mast cell tumours within the dermis. In addition multifocal to diffuse mast cell aggregations were observed in several internal organs including the lymph nodes and the bone marrow. No evidence for the presence of bovine leukemia virus was found by both investigating a lymph node homogenate of the calf and a blood sample of the mother cow. In this paper the pathomorphology of this rare disease is described, a possible cause is discussed and a short review of the available literature is presented.
Müller
M
M
Bayerischen Landesamt für Gesundheit und Lebensmittelsicherheit, Erlangen.
Breuer
W
W
Nitzschke
K
K
Drost
G
G
Krisch
A
A
Schmid
M
M
Bogner
K H
KH
Beier
D
D
D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D017809:Fatal Outcome; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D034701:Mastocytosis, Cutaneous / Q000473:pathology / Q000662:veterinary*; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*