[Biological and pathological data in a case of yellow fever imported from the Gambia].
A 47-year-old woman developed fever and asthenia 1 week after having traveled to Gambia. Four days after the first symptoms, she was transferred to the intensive care unit. She was in poor general condition, with anuria and jaundice. Liver function tests showed severely disturbed function and the diagnosis of yellow fever infection was made by RT-PCR in this patient who had not been vaccinated. Encephalopathy appeared on day 7 and death occurred on day 8 due to massive gastrointestinal bleeding. At autopsy, extensive panlobular liver necrosis was observed together with the presence of numerous Councilman bodies in the three hepatic zones.
Département d'Anatomie Pathologique, Cliniques St-Luc, Université catholique de Louvain, Bruxelles, Belgique.
Muriel
M
Parent
Philippe
P
Hantson
Patrick
P
Honore
Robert
R
Colebunders
Jacques
J
Rahier
Frédéric
F
Bonbled
D001002:Anuria / Q000209:etiology; D001530:Belgium; D003424:Crohn Disease / Q000150:complications; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005334:Fever / Q000209:etiology; D005714:Gambia; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006501:Hepatic Encephalopathy / Q000209:etiology; D006525:Hepatitis, Viral, Human / Q000175:diagnosis; D006801:Humans; D008099:Liver / Q000473:pathology; D008288:Malaria / Q000175:diagnosis; D008875:Middle Aged; D009336:Necrosis; D012771:Shock, Hemorrhagic / Q000209:etiology; D014195:Travel; D015004:Yellow Fever / Q000175:diagnosis / Q000473:pathology*