[Expression of aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig].
OBJECTIVE
To detect the expression of Aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig.


METHODS
Two-step immunohistochemical method and immunofluorescence was used to examine the expression of Aquaporin-1,3.


RESULTS
Aquaporin-1 was expressed on the basilar part of spiral ligament, basal membrane of Corti's organ and epithelialis of scala tympani, and basilar part under the cellular epithelialis in endolymphatic sac. Aquaporin-3 was expressed on stria vascularis, spiral ligament, Corti's organ, spiral ganglion and, the basilar part and the cellular epithelialis in endolymphatic sac.


CONCLUSIONS
Aquaporin-1,3 were widely expressed in the cochlea and endolymphatic sac of guinea pig.
Institute of Otolaryngology, General Hospital of PLA, Beijing, 100853, China.
Qi
Q
Li
Lin
L
Lin
Yinyan
Y
Hu
Deliang
D
Huang
D000818:Animals; D051398:Aquaporin 1 / Q000378:metabolism*; D051400:Aquaporin 3 / Q000378:metabolism*; D003051:Cochlea / Q000378:metabolism*; D004712:Endolymphatic Sac / Q000378:metabolism*; D006168:Guinea Pigs
D051398:Aquaporin 1; D051400:Aquaporin 3