Airbag asthma: a case report and review of the literature.
BACKGROUND
Although airbags are a significant development in automobile safety, they have brought with them new medical problems.


OBJECTIVE
To describe a case of new-onset asthma occurring after exposure to a deployed airbag's contents.


METHODS
A 47-year-old man had a 2.5-year history of chest tightness, decreased exercise tolerance, and nocturnal and activity-associated cough beginning after a head-on motor vehicle collision when he was driving an automobile equipped with dual driver-passenger airbags. The collision activated both airbags, with the driver's side airbag breaking open, filling the automobile with particulates. The driver remained in the car for 3 minutes and developed acute shortness of breath and chest tightness for the first time in his life. He had a smoking history of 1 pack-year 20 years earlier. Before that time he could exercise frequently, running for 30 minutes almost daily without difficulty. After the collision, he had respiratory symptoms at rest and after exercise, requiring daily control and rescue medication. Subsequently, he developed bronchospasm following exposure to nonspecific agents, which he had never previously experienced.


RESULTS
Skin test reactivity was detectable only to dust mite. Methacholine challenge results were markedly positive at 8 weeks and 2.5 years after the incident. Video laryngoscopy revealed normal vocal cord appearance and function.


CONCLUSIONS
Our patient represents the first case, to our knowledge, of new-onset, persistent, irritant-induced asthma following airbag deployment. Physicians should be aware of its possibility after airbag exposure, since prompt institution of aggressive therapy may improve patient outcome and dampen or prevent persistent disease.
Hambrook
Daniel W
DW
Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. danielh@mcw.edu
Fink
Jordan N
JN
D000063:Accidents, Traffic; D017278:Air Bags / Q000009:adverse effects*; D001249:Asthma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects*; D008297:Male; D016210:Methacholine Chloride / Q000494:pharmacology; D008875:Middle Aged; D012882:Skin Tests
D016210:Methacholine Chloride