Serotonergic mechanisms: a potential link between affective disorders and cardiovascular risk.
Cardiovascular disease and major depression are highly prevalent disorders in our society. Evidence has been found that confirms a reciprocal relationship between mechanisms of depression and those of cardiovascular pathology. This possible feedback between both pathologies is a subject of great concern. In recent years some studies suggest that platelets and serotonergic mechanisms could be involved in both conditions. The present review seeks a better understanding of the mechanisms that could link depression with an enhanced cardiovascular risk.
Servicio de Hemoterapia y Hemostasia, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Faculty of Medicine, University of Barcelona, Barcelona, Spain.
Ginés
G
Escolar
Maribel
M
Díaz-Ricart
Esther
E
Gomez-Gil
Montserrat
M
Serra
Cristobal
C
Gasto
Jordi
J
Bozzo
Ana Maria
AM
Galán