Radiotherapy with laser-plasma accelerators: Monte Carlo simulation of dose deposited by an experimental quasimonoenergetic electron beam.
The most recent experimental results obtained with laser-plasma accelerators are applied to radio-therapy simulations. The narrow electron beam, produced during the interaction of the laser with the gas jet, has a high charge (0.5 nC) and is quasimonoenergetic (170 +/- 20 MeV). The dose deposition is calculated in a water phantom placed at different distances from the diverging electron source. We show that, using magnetic fields to refocus the electron beam inside the water phantom, the transverse penumbra is improved. This electron beam is well suited for delivering a high dose peaked on the propagation axis, a sharp and narrow tranverse penumbra combined with a deep penetration.
Laboratoire d'Optique Appliquée-ENSTA, UMR 7639, CNRS, Ecole Polytechnique, 91761 Palaiseau, France.
Y
Y
Glinec
J
J
Faure
V
V
Malka
T
T
Fuchs
H
H
Szymanowski
U
U
Oelfke
D001822:Body Burden; D003198:Computer Simulation; D004583:Electrons / Q000627:therapeutic use*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D005740:Gases; D006358:Hot Temperature; D053685:Laser Therapy; D008954:Models, Biological; D015233:Models, Statistical; D009010:Monte Carlo Method; D010315:Particle Accelerators / Q000295:instrumentation*; D011874:Radiometry / Q000379:methods*; D011878:Radiotherapy / Q000295:instrumentation* / Q000379:methods*; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness
D005740:Gases