Expression of cadherin10, a type II classic cadherin gene, in the nervous system of the embryonic zebrafish.
Cadherins are cell surface adhesion molecules that play important roles in development of tissues and organs. In this study, we analyzed expression pattern of cadherin10, a member of the type II classic cadherin subfamily, in the embryonic zebrafish using in situ hybridization methods. cadherin10 message (cdh10) is first and transiently expressed by the notochord. In the developing nervous system, cdh10 was first detected in a subset of the cranial ganglia, then in restricted brain regions and neural retina. As development proceeds, cdh10 expression domain and/or expression levels increased in the embryonic nervous system. Our results show that cdh10 expression in the zebrafish developing nervous system is both spatially and temporally regulated.
Liu
Qin
Q
Department of Biology, University of Akron, OH, USA.
Duff
Robert J
RJ
Liu
Bei
B
Wilson
Amy L
AL
Babb-Clendenon
Sherry G
SG
Francl
Jessie
J
Marrs
James A
JA
D000595:Amino Acid Sequence; D000818:Animals; D015820:Cadherins / Q000737:chemistry / Q000235:genetics*; D002490:Central Nervous System / Q000196:embryology* / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016415:Sequence Alignment; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics*; D029961:Zebrafish Proteins / Q000737:chemistry / Q000235:genetics*
D015820:Cadherins; D029961:Zebrafish Proteins; C513924:cdh10a protein, zebrafish