Surgical and radiotherapy treatment of a spinal cord ependymoma in a dog.
A 4-year-old Beagle dog was presented for investigation of a left pelvic limb gait abnormality. Neurolocalisation indicated a lumbar (L2 to L5) spinal cord lesion. On magnetic resonance imaging (MRI), an intramedullary mass was demonstrated at L3. The mass was partially removed under general anaesthesia and a diagnosis of ependymoma was made on histological examination. The dog was treated with postoperative orthovoltage x-ray radiation (total dose; 44 Gy given in 11 fractions over a 4 week period) combined with low dose carboplatin (25 mg/m2). The dog was alive 16 months after surgery without further neurological deficits. No further tumour growth was detected on subsequent MRI evaluations.
Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan. uehiro@cc.gifu-u.ac.jp
H
H
Ueno
M
M
Morimoto
Y
Y
Kobayashi
T
T
Hizume
N
N
Murayama
Y
Y
Uzuka
D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D004285:Dogs; D004806:Ependymoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome