Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance.
Equine herpesvirus (EHV)-1 is a pathogen of horses, well known for its ability to induce abortion and nervous system disorders. Clinical signs may occur despite the presence of a virus-specific immune response in the horse. The current review will summarize the research, on how, EHV-1-infected cells can hide from recognition by the immune system. Research findings on immune evasion of EHV-1 will be compared with those of other herpesviruses of veterinary importance.
Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. karen.vandermeulen@ugent.be
Karen M
KM
van der Meulen
Herman W
HW
Favoreel
Maurice B
MB
Pensaert
Hans J
HJ
Nauwynck
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D016207:Cytokines / Q000276:immunology; D006566:Herpesviridae Infections / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D004861:Herpesvirus 1, Equid / Q000276:immunology*; D006734:Horse Diseases / Q000276:immunology* / Q000821:virology*; D006736:Horses; D014764:Viral Proteins / Q000276:immunology
D000914:Antibodies, Viral; D016207:Cytokines; D014764:Viral Proteins