Susceptibility of several macrolides and a ketolide against clinically isolated 'Streptococcus milleri' group.
The susceptibility of four macrolides (erythromycin, clarithromycin, roxithromycin and azithromycin) and a ketolide (telithromycin) was tested using 58 clinically isolated strains of the 'Streptococcus milleri' group (SMG). Among the 58 strains, 9 strains were determined to be resistant to erythromycin as well as other macrolides. Of the four macrolides and the ketolide, telithromycin was the most effective antibiotic against the SMG, including the erythromycin-resistant strains.
Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases (First Department of Internal Medicine), Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0215, Japan.
Natsuo
N
Yamamoto
Jiro
J
Fujita
Futoshi
F
Higa
Masao
M
Tateyama
Isamu
I
Nakasone
Nobuhisa
N
Yamane
D006801:Humans; D048628:Ketolides / Q000494:pharmacology*; D018942:Macrolides / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D034364:Streptococcus milleri Group / Q000187:drug effects* / Q000302:isolation & purification*
D048628:Ketolides; D018942:Macrolides