Sequential formation of a ternary complex among dihexylammonium, cucurbit[6]uril, and cyclodextrin with positive cooperativity.
A unique ternary 1:1:1 cucurbit[6]uril (CB[6])-cyclodextrin (CD)-dihexylammonium (DHA) complex was designed and noncovalently synthesized in stepwise fashion: first, CB[6] interacts strongly with DHA to form a 1:1 complex; second, addition of CD into the solution of the 1:1 complex leads to the exclusive formation of the 1:1:1 ternary complex. The ternary complex was characterized by various experimental techniques including ITC, NMR, and ESI-MS.
Entropy Control Project, ICORP, JST, 4-6-3 Kamishinden, Toyonaka 560-0085, Japan.
Mikhail V
MV
Rekharsky
Hatsuo
H
Yamamura
Masao
M
Kawai
Issey
I
Osaka
Ryuichi
R
Arakawa
Akihiro
A
Sato
Young Ho
YH
Ko
N
N
Selvapalam
Kimoon
K
Kim
Yoshihisa
Y
Inoue
D001952:Bridged-Ring Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013816:Thermodynamics; D047392:beta-Cyclodextrins / Q000138:chemical synthesis / Q000737:chemistry*; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
D001952:Bridged-Ring Compounds; D007093:Imidazoles; D000644:Quaternary Ammonium Compounds; D047392:beta-Cyclodextrins; C454805:cucurbit(6)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils