Commensal bacteria influence Escherichia coli O157:H7 persistence and Shiga toxin production in the mouse intestine.
The presence of commensal flora reduced colonization of Escherichia coli O157:H7 and production of Shiga toxin (Stx) in the murine intestine. Stx production was not detected in mice colonized with E. coli that were resistant to the Shiga toxin phage, but it was detected in mice colonized with phage-susceptible E. coli.
Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267-0524, USA.
Shantini D
SD
Gamage
Angela K
AK
Patton
Jane E
JE
Strasser
Claudia L
CL
Chalk
Alison A
AA
Weiss
D000818:Animals; D004927:Escherichia coli Infections; D019453:Escherichia coli O157 / Q000378:metabolism* / Q000472:pathogenicity / Q000821:virology; D007422:Intestines / Q000382:microbiology*; D051379:Mice; D022621:Shiga Toxin / Q000096:biosynthesis*; D013559:Symbiosis
D022621:Shiga Toxin