Lessons learned fighting HIV can be applied to anti-cancer drug design.
Protein Structure Section, Macromolecular Crystallography Laboratory, NCI at Frederick, Frederick, Maryland 21702, USA.
Alla
A
Gustchina
Mariusz
M
Jaskólski
Alexander
A
Wlodawer
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors / Q000378:metabolism; D006800:Deltaretrovirus Infections / Q000188:drug therapy / Q000201:enzymology; D015195:Drug Design; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000494:pharmacology; D006801:Humans; D008958:Models, Molecular
D000970:Antineoplastic Agents; D017320:HIV Protease Inhibitors; D016282:Aspartic Acid Endopeptidases; C079711:HTLV-1 protease