Disseminate and fatal cytomegalovirus disease with thymitis in a naive HIV-patient after early initiation of HAART: immune restoration disease?
We describe a naive HIV-infected patient who developed a Pneumocystis carinii pneumonia and disseminate and fatal cytomegalovirus disease within 3 months after initiation of HAART, suggesting due to coincidence in time, an immune restoration disease. We propose an alternative hypothesis.
Department of Internal Medicine, Virgen del Rocio University Hospital, Seville, Spain.
Sonia
S
Gutiérrez
Silvia
S
Alconchel
Ezequiel
E
Ruiz-Mateos
Miguel
M
Genebat
Alejandro
A
Vallejo
Eduardo
E
Lissen
Jorge
J
Fernández-Alonso
Manuel
M
Leal
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology* / Q000821:virology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D003586:Cytomegalovirus Infections / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007150:Immunohistochemistry; D007181:Inclusion Bodies, Viral / Q000378:metabolism; D008168:Lung / Q000821:virology; D008482:Mediastinum / Q000000981:diagnostic imaging; D008590:Meningoencephalitis / Q000473:pathology; D011020:Pneumonia, Pneumocystis / Q000276:immunology*; D012367:RNA, Viral / Q000097:blood; D011859:Radiography; D011948:Receptors, Antigen, T-Cell / Q000032:analysis; D013950:Thymus Gland / Q000821:virology; D013997:Time Factors; D019562:Viral Load
D012367:RNA, Viral; D011948:Receptors, Antigen, T-Cell