[Congenital transmission of Trypanosoma cruzi in Brazil: estimation of prevalence based on preliminary data of national serological surveys in children under 5 years old and other sources].
A prevalence estimation of congenital transmission in Brazil is performed, based on several sources of recent data. From a serological survey conducted now in Brazil, with children below 5 years old, preliminary data from the state of Minas Gerais only 19/9,556 children did have antibodies against Trypanosoma cruzi. All 19 mothers were infected, but only one child persisted with antibodies on a second blood collection, hence diagnosed as congenital. The other were just passive transference of maternal antibodies. From a recent publication, 278 children born from 145 infected mothers were studied. Two cases (0.7%) were congenital. In other source, from 1,348 blood donors, 35 were born in non endemic areas. When 10 of them were called, 8 were born from infected mothers and five may be congenital. Finally, no infection was detected in 93 children born from 78 infected mothers. The reasons for this low prevalence are discussed, are lower than in other countries of the South Cone, that harbor also T. cruzi 2, but are unrecognized up to now.
Luquetti
Alejandro O
AO
Laboratório de Pesquisa da doença de Chagas, Hospital das Clínicas, Universidade Federal de Goias (UFG), Goiânia, Brasil. luquetti@hc.ufg.br
Ferreira
António Walter
AW
Oliveira
Rosângela A
RA
Tavares
Suelene B N
SB
Rassi
Anis
A
Dias
João Carlos P
JC
Prata
Aluizio
A
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000097:blood / Q000453:epidemiology / Q000635:transmission*; D002675:Child, Preschool; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000706:statistics & numerical data*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic; D015995:Prevalence; D014349:Trypanosoma cruzi
D000913:Antibodies, Protozoan