Hypocalcaemia following therapy of thyrotoxicosis in an infant.
A 2-mo-old infant born to a mother with Graves' disease and having symptoms of thyrotoxicosis was started on antithyroid drugs. Life-threatening hypocalcaemia requiring high-dose calcium infusions developed 1 mo after starting therapy. Serum alkaline phosphatase and paratharmone levels were elevated. This communication may serve to alert treating physicians about this rare complication in infants with thyrotoxicosis after initiation of antithyroid therapy.


CONCLUSIONS
Severe hypocalcaemia may follow initiation of antithyroid therapy in infants with thyrotoxicosis.
Kansra
Sonal
S
Department of Paediatrics, Advanced Paediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India. devbijaya@yahoo.co.in
Devidayal
Suri
Deepti
D
Singh
Meenu
M
D013956:Antithyroid Agents / Q000009:adverse effects*; D006111:Graves Disease / Q000150:complications* / Q000151:congenital / Q000175:diagnosis; D006801:Humans; D006996:Hypocalcemia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D007223:Infant; D008297:Male; D013971:Thyrotoxicosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology
D013956:Antithyroid Agents