Effect of low power laser irradiation on disconnecting the membrane-attached hemoglobin from erythrocyte membrane.
In our previous study we found that low power laser irradiation improved the erythrocyte deformability, but the mechanism is unclear. The membrane-attached hemoglobin (Hbm) may be one of the determining factors for the erythrocyte deformability. We report here for the first time, that laser irradiation can reduce the Hbm contents in pig's erythrocytes, providing the explanation for the improvement of erythrocyte deformability. The decrease of the Hbm was proportional to the irradiation dose, but the relative change of Hbm was saturated around 35%. The 532 nm laser was more efficient at lowering Hbm than the 632.8 nm laser, consistent with the absorption spectrum of Hbm.
Mi
X Q
XQ
Department of Physics, Fudan University, Shanghai 200433, China; State Key Laboratory of Applied Surface Physics, Fudan University, Shanghai, China.
Chen
J Y
JY
Zhou
L W
LW
D000818:Animals; D004907:Erythrocyte Deformability / Q000528:radiation effects; D004910:Erythrocyte Membrane / Q000737:chemistry* / Q000528:radiation effects*; D006454:Hemoglobins / Q000737:chemistry* / Q000528:radiation effects*; D066298:In Vitro Techniques; D028022:Low-Level Light Therapy; D018462:Photobiology; D034421:Sus scrofa
D006454:Hemoglobins