Treatment of tension-type headache with botox: a review of the literature.
Botulinum toxin has been shown to effectively treat several types of neurological disorders. It has recently been evaluated for the treatment of tension-type headaches in patients who are unable to tolerate or cannot benefit from standard therapies. Most of the open design studies seem to present positive results. However, the randomized, double-blind, placebo-controlled studies present contradictory results for the efficacy of botulinum toxin. Based on these data, further controlled trials of botulinum toxin are needed to evaluate its effects on tension headaches and to determine optimal injection sites, doses, and frequency of treatments.
Department of Anesthesiology and Pain Management, Box 1010, Mount Sinai Medical Center, One East 100th Street, New York, NY 10029-6574, USA. dimarozen@hotmail.com
Dima
D
Rozen
Joyti
J
Sharma
D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D006801:Humans; D007267:Injections; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018781:Tension-Type Headache / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A