Sulfation: a new biocombinatorial tool.
Considerable progress has been achieved in derivatization of glycopeptide antibiotics by using genetic engineering and in vitro enzymatic approaches. In this issue of Chemistry & Biology, the identification and application of a glycopeptide-specific sulfotransferase by Lamb et al. expands the tool box of biocombinatorial synthesis.
Combinature Biopharm AG, Berlin, Germany.
Stefan
S
Pelzer
Agnieszka
A
Dziarnowski
D000900:Anti-Bacterial Agents / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D005818:Genetic Engineering; D013431:Sulfates / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D013431:Sulfates