Use of dexmedetomidine in awake craniotomy in adolescents: report of two cases.
Awake craniotomy is a key tool in resection of lesions near critical functional regions, particularly the speech area. Craniotomy with an awake portion for mapping may be performed in carefully selected adolescents and preteenaged children. A number of different regimens may be used for sedation and anesthesia in these cases. We describe two adolescent patients in whom awake craniotomy was performed using an intravenous anesthesia technique with dexmedetomidine and without need for airway instrumentation.
Department of Pediatric Anesthesiology, University of Washington, Seattle, WA, USA. leverett@partners.org
Lucinda L
LL
Everett
Inge F
IF
van Rooyen
Molly H
MH
Warner
Hillary A
HA
Shurtleff
Russell P
RP
Saneto
Jeffrey G
JG
Ojemann
D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000601:surgery; D016292:Procedural Sedation; D003399:Craniotomy; D020927:Dexmedetomidine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D008297:Male; D009837:Oligodendroglioma / Q000150:complications / Q000601:surgery; D015742:Propofol / Q000008:administration & dosage; D012640:Seizures / Q000209:etiology / Q000601:surgery; D014851:Wakefulness
D018712:Analgesics, Non-Narcotic; D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine; D015742:Propofol