[Anlysis on features of dead cases with human Streptococcus suis infections].
OBJECTIVE
To describe the clinical and epidemiological features of dead cases with human Streptococcus suis infections, and to find the target population for preventing death and the related indicators.


METHODS
Epidemiological investigation on human Streptococcus suis infections was implemented used unified questionnaires. Analysis on dead cases and survival cases (as contrast) was done.


RESULTS
The population with highest fatality rate was in 40-49 age group. 97.37% of dead cases had toxic shock syndrome. The mean interval from onset to admission was 0.76 days, and the mean course was 2.11 days. The progression among dead cases was faster than that among survival cases. Chief clinical manifestations of dead cases that are more frequent than survival cases are purpura (73.68%), diarrhea (50.0%), dyspnea (21.05%), conjunctival congestion (34.21%), etc. Renal impairment and liver involvement in dead cases were more significant than that in survival cases. No significant difference between mean incubation period, exposure rates of main risk factors in dead cases and in survival cases was found.


CONCLUSIONS
Preventing toxic shock syndrome might reduce the fatality rate. The target population for preventing death is aged > or = 40. Liver function and renal function testing might be indicators for monitoring the progression of human Streptococcus suis infections.
Zhu
Xiao-ping
XP
Sichuan Provincial Center for Disease Control and Provention, Chengdu 610031, China.
Zu
Rong-qiang
RQ
Chen
Zhi-hai
ZH
Liu
Xue-cheng
XC
Liu
Lun-guang
LG
Zhong
Wen-jun
WJ
Wang
Shi-wen
SW
Xiang
Ni-juan
NJ
Yuan
Heng
H
Meng
Ling
L
Ou
Yang-bing
YB
Gao
Yong-jun
YJ
Lv
Qiang
Q
Huang
Yan
Y
An
Xiang-dong
XD
Huang
Ting
T
Zhou
Xing-yu
XY
Feng
Liao
L
Pang
Qi-di
QD
Yang
Wei-zhong
WZ
D000328:Adult; D000368:Aged; D002681:China; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013290:Streptococcal Infections / Q000097:blood / Q000382:microbiology* / Q000401:mortality* / Q000473:pathology; D017011:Streptococcus suis / Q000502:physiology*; D055815:Young Adult