Retrospective clinical and radiologic evaluation of nonsurgical endodontic treatment in human immunodeficiency virus (HIV) infection.
OBJECTIVE
This retrospective study evaluated the clinical and radiographic status of nonsurgical endodontic treatment (ET) of anterior and posterior teeth in HIV-seropositive patients.


METHODS
ET was analyzed in 26 anterior and 34 posterior teeth from 54 consecutive HIV patients (gender ratio 3 Male : 1 Female, mean age 40.2 years, mean CD4 240, CD4<500 in 88%, 12 with AIDS) over a six year period with a minimum of six months follow-up. ET was evaluated as successful, questionable, or failure based upon clinical factors (palpation, mobility, sinus tract, percussion, function, infection/swelling, occlusion, symptoms) and radiographic factors (periodontal ligament space, rarefaction, lamina dura, root resorption, obturation) during post-treatment examinations with a mean follow up of 26 months.


RESULTS
Clinical evaluation at follow up found ET outcome was successful in 88%, questionable in 10% (tenderness with percussion, mobility, widened ligament), and a failure in 2% (developed lesion after ET). Periapical lesions were present in 37% of cases (mean lesion size 6.2 mm). Following ET, mean lesion size (1.8 mm) had decreased by 71%. Obturation was evaluated as optimal or acceptable in 68%. Radiographic evaluation was considered successful in 80%, no change in 15%, and a failure in 5%.


CONCLUSIONS
Despite obturation deficiencies and the immunocompromised state of the patients, endodontic therapy has a relatively high degree of success in the majority of HIV/AIDS patients. HIV infection and AIDS should not be considered as a contraindication to endodontic therapy in this patient population.
Suchina
John A
JA
Department of Endodontics, University of Texas Health Science Center, Houston, TX, USA.
Levine
Debora
D
Flaitz
Catherine M
CM
Nichols
C Mark
CM
Hicks
M John
MJ
D000328:Adult; D000704:Analysis of Variance; D018791:CD4 Lymphocyte Count; D017742:Dental Care for Chronically Ill; D003751:Dental Fistula / Q000209:etiology; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections; D006801:Humans; D008297:Male; D010485:Periapical Periodontitis / Q000209:etiology; D011859:Radiography; D012189:Retrospective Studies; D012390:Root Canal Therapy / Q000009:adverse effects / Q000379:methods*; D012391:Root Resorption / Q000000981:diagnostic imaging / Q000209:etiology; D018709:Statistics, Nonparametric; D014086:Tooth Mobility / Q000209:etiology; D014092:Tooth Root / Q000000981:diagnostic imaging; D016896:Treatment Outcome