Efficient synthesis of C-11 functionalized steroids.
An efficient synthesis from readily available materials of numerous steroids functionalized at C-11 position, interesting from a biological point of view, is described using our general approach. The characteristic (1)H and (13)C NMR spectroscopic features of the synthesized steroids are reported.
UMR 6180 CNRS and Université d'Aix Marseille III: "Chirotechnologies: catalyse et biocatalyse", Laboratoire de Synthèse Organique associé au CNRS, Faculté des Sciences et Techniques de Saint Jérôme, 13397 Marseille Cedex 20, France.
Patrick
P
Bazzini
Malika
M
Ibrahim-Ouali
Hélène
H
Pellissier
Maurice
M
Santelli
D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry*
D009570:Nitriles; D013256:Steroids