[Anesthesia in patients with glucose-6-phosphate dehydrogenase deficiency: case report and perioperative anesthesiologic management].
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a frequent congenital human enzyme defect, is the most frequent cause of hemolytic anemia triggered by drugs or infectious diseases. Drugs which induce acute hemolysis in patients with G6PD deficiency are often used in anesthesia and perioperative pain therapy. Considering the fact that patients from geographic regions with a high prevalence of the disease are often treated in European hospitals, special attention should be paid to this problem. We report a case of a 30-year-old female patient with favism and review the disease and anesthesia-related implications.
Depta
A L
AL
Klinik für Anästhesiologie, Johannes Gutenberg-Universität, Mainz, Germany. depta@anaesthesie.klinik.uni-mainz.de
Erdös
G
G
Werner
C
C
D000328:Adult; D000758:Anesthesia; D000777:Anesthetics / Q000009:adverse effects; D003937:Diagnosis, Differential; D005236:Favism / Q000097:blood / Q000150:complications* / Q000235:genetics; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood / Q000150:complications* / Q000235:genetics; D005978:Glutathione / Q000378:metabolism; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D011229:Preanesthetic Medication; D013965:Thyroidectomy
D000777:Anesthetics; D005978:Glutathione