Indocyanine green angiographic findings for patients with systemic lupus erythematosus nephropathy.
OBJECTIVE
To study indocyanine green (ICG) angiographic findings for patients with systemic lupus erythematosus (SLE) nephropathy. In particular, the presence of choroidal abnormalities at ICG angiography, which could not be detected by fluorescein angiography, was studied.


METHODS
Observational case report study.


METHODS
Nine consecutive female patients (mean age +/- SD, 38.2 +/- 9.7 years) with SLE-related nephropathy underwent simultaneous ICG angiography and fluorescein angiography according to a standard angiographic protocol for uveitis.


RESULTS
Two findings were revealed by ICG angiography: focal, transient hypofluorescent areas in the early phase; and spots of choroidal hyperfluorescence visible from the intermediate to late phase.


CONCLUSIONS
ICG angiography can provide information that is not detectable by clinical or fluorescein angiographic examination for patients with lupus nephropathy. This information may prove useful in better understanding the pathogenesis of SLE choroidopathy.
Gharbiya
Magda
M
Department of Ophthalmology, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy. magda.gharbiya@tiscalinet.it
Pecci
Gabriella
G
Baglio
Veronica
V
Gargiulo
Antonio
A
Allievi
Francesca
F
Balacco-Gabrieli
Corrado
C
D000328:Adult; D002829:Choroid / Q000098:blood supply; D015862:Choroid Diseases / Q000175:diagnosis*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007208:Indocyanine Green; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D008181:Lupus Nephritis / Q000175:diagnosis*; D008875:Middle Aged
D004396:Coloring Agents; D007208:Indocyanine Green