[Metabolic control by means of insulin in patients with type 2 diabetes and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity--secondary publication].
Patients with diabetes have an unfavourable prognosis after an acute myocardial infarction. The DIGAMI 2 study investigated the effect of various metabolic treatment strategies in type 2 diabetic patients with acute myocardial infarction: acutely introduced, long-term insulin treatment did not improve survival when compared with conventional management at similar levels of glucose control. However, good glucose control seems important since the glucose level was found to be a strong predictor of long-term mortality in this patient category.
H:S Frederiksberg Hospital, Kardiologisk-endokrinologisk Klinik E, DK-2000 Frederiksberg. gustafsson@dadlnet.dk
Ida
I
Gustafsson
Klas
K
Malmberg
Lars
L
Rydén
Hans
H
Wedel
Kåre
K
Birkeland
Aart
A
Bootsma
Kenneth
K
Dickstein
Suad
S
Efendic
Miles
M
Fisher
Anders
A
Hamsten
Johan
J
Herlitz
Per Rossen
PR
Hildebrandt
Kenneth
K
MacLeod
Markku
M
Laakso
Christian T
CT
Torp-Pedersen
Anders
A
Waldenström
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D011379:Prognosis
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin