[Determination of organochlorine pesticide residue in nine Chinese herbs by gas chromatography].
OBJECTIVE
To determine organochlorine pesticide residue in 9 Chinese herbs.


METHODS
The organochlorine pesticides were extracted from the herbs with mixed solvents of n-hexane and acetone by a solid-phase extraction cartridge Florisil. Capillary gas chromatography was used to separate the samples.


RESULTS
Good linearities were obtained for 11 organochlorine pesticides. The average recoveries at two concentration levels ranged from 79.9% to 89.0%,and from 86.3% to 104.8%, with relative standard deviations of 1.8% to 7.1%, respectively and detection limit of 2 g/kg. The residues of the organic pesticides exceeded national standard in Pogostemon cablin and Panax notoginseng.


CONCLUSIONS
Capillary gas chromatography combined with electron capture detection provides a practical means for detecting organic pesticide residue in Chinese herbal medicines, and the limits of pesticide residues should be formulated in Chinese pharmacopoeia.
Yang
Xue-mei
XM
College of Pharmacy, Southern Medical University, Guangzhou 510515, China. xujp@fimmu.com
Zhong
Huai-ning
HN
Yan
Yi-chen
YC
Yi
Rong
R
Xu
Jiang-ping
JP
D002849:Chromatography, Gas; D004340:Drug Contamination; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*
D004365:Drugs, Chinese Herbal; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues