Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret.
A 2-year-old domestic ferret that appeared clinically healthy was repeatedly seropositive for Aleutian mink disease parvovirus (ADV) over a 2-year observation period. Antibody titers, determined by counter-immunoelectrophoresis, ranged from 1024 to 4096. Viral DNA also was identified in serum, urine, feces, and blood cell fractions by polymerase chain reaction analysis. Ultimately, DNA in situ hybridization revealed ADV DNA in histologic sections of various tissues and organs. These data indicate that this asymptomatic ferret was persistently infected with ADV.
Pennick
Kate E
KE
Department of Pathology, University of Georgia College of Veterinary Medicine, Athens 30602, USA.
Stevenson
Mary Ann M
MA
Latimer
Kenneth S
KS
Ritchie
Branson W
BW
Gregory
Christopher R
CR
D000453:Aleutian Mink Disease / Q000821:virology*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002353:Carrier State / Q000503:physiopathology / Q000821:virology*; D004279:DNA, Viral; D005289:Ferrets / Q000502:physiology / Q000821:virology*; D007668:Kidney / Q000821:virology; D008099:Liver / Q000821:virology; D008168:Lung / Q000821:virology; D008297:Male; D013154:Spleen / Q000821:virology; D014556:Urine / Q000821:virology; D017201:Virus Shedding
D000914:Antibodies, Viral; D004279:DNA, Viral