CvP-bias as an index to predict the life style of last common ancestor.
CvP-bias (difference between proportions of charged and polar non-charged amino acids) has been recognized as an efficient criterion to distinguish hyperthermophiles from mesothermophiles. By analyzing the CvP-biases of seven barophiles's proteomes, we reveal that this criterion still works for barophiles. As a result, CvP-bias criterion is applicable to disclosing some secrets in the lifestyles of the last common ancestor (LCA), no matter the LCA lived in deep sea or not, which is helpful to building a self-consistent model for the LCA.
Ma
Bin-Guang
BG
Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Center for Advanced Study, Shandong University of Technology, Zibo 255049, P. R. China.
Song
Qin-Song
QS
Zhang
Hong-Yu
HY
D000596:Amino Acids / Q000032:analysis; D001105:Archaea / Q000145:classification / Q000235:genetics*; D019843:Archaeal Proteins / Q000235:genetics*; D019143:Evolution, Molecular; D020543:Proteome; D013816:Thermodynamics
D000596:Amino Acids; D019843:Archaeal Proteins; D020543:Proteome