Preliminary assessment of genome differences between the reference Nine Mile isolate and two human endocarditis isolates of Coxiella burnetii.
This study investigates the complete genome sequences of the Nine Mile, K, and G isolates to improve our understanding of the unique virulence properties of C. burnetii and to provide important insight into the genome architecture and genetic diversity of this pathogen.
Beare
Paul A
PA
Coxiella Pathogenesis Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA.
Porcella
Stephen F
SF
Seshadri
Rekha
R
Samuel
James E
JE
Heinzen
Robert A
RA
D000208:Acute Disease; D000818:Animals; D002642:Chick Embryo; D016997:Coxiella burnetii / Q000235:genetics* / Q000302:isolation & purification* / Q000472:pathogenicity; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D016680:Genome, Bacterial; D006801:Humans; D011778:Q Fever / Q000382:microbiology*; D014774:Virulence