Vicinal diamino functionalities as privileged structural elements in biologically active compounds and exploitation of their synthetic chemistry.
The chemistry, synthetic routes and medicinal properties of vicinal diamines and imidazolines are discussed. Synthetic routes towards chemically and pharmaceutically important molecules containing vicinal diamine functionality are discussed in detail. This mini review article covers the new developments of diamine chemistry between 2000 and 2005.
Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
S R S
SR
Saibabu Kotti
Cody
C
Timmons
Guigen
G
Li
D003959:Diamines / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D048288:Imidazolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D010600:Pharmacology / Q000639:trends
D003959:Diamines; D048288:Imidazolines