[A study of the safety of probiotic bacilli].
The aim of the study was to evaluate the biological safety of a range of probiotic bacilli, ingredients of the commercial preparations biosporin, bactisubtil, and irilis; their biological effects were scrutinized in an animal experiment. The study demonstrated that the strains B. subtilis 3, 07, and B. licheniformis 31, 09, ingredients of biosporin and irilis, unlike B. cereus IP 5832, an ingredient of bactisubtil, were not toxic, toxigenic, or virulent, and did not impair the antitoxic hepatic function, which allows considering them to be safe.
Sorokulova
I B
IB
Osipova
I G
IG
Tereshkina
N V
NV
Vasil'eva
E A
EA
Budanova
E V
EV
D000818:Animals; D001407:Bacillus / Q000472:pathogenicity; D001409:Bacillus cereus / Q000472:pathogenicity; D001412:Bacillus subtilis / Q000472:pathogenicity; D001685:Biological Factors; D005260:Female; D008099:Liver / Q000187:drug effects; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D019936:Probiotics / Q000494:pharmacology / Q000592:standards* / Q000633:toxicity; D012449:Safety; D013997:Time Factors; D014774:Virulence
D001685:Biological Factors; C089800:bactisubtil; C091592:biosporin