[Prognostic value of N-terminal pro-BNP-type natriuretic peptide in patients with stable coronary heart disease--secondary publication].
We assessed the relationship between NT-proBNP levels and all-cause mortality in patients with stable coronary heart disease. NT-proBNP was measured in 1,034 patients referred for elective coronary angiography. In a multivariable Cox regression analysis, the hazard ratio for death from any cause for patients with NT-proBNP levels in the fourth quartile as compared with those in the first quartile was 2.4 (95% CI 1.5-4.0). NT-proBNP provides prognostic information on all-cause mortality independent of conventional cardiovascular risk factors and left ventricular dysfunction.
H:S Frederiksberg Hospital, Kardiologisk-endokrinologisk Klinik E, DK-2000 Frederiksberg. kragelund@dadlnet.dk
Charlotte B
CB
Kragelund
Bjørn Aaris
BA
Grønning
Lars
L
Køber
Per Rossen
PR
Hildebrandt
Rolf
R
Steffensen
D000368:Aged; D015415:Biomarkers / Q000097:blood*; D003327:Coronary Disease / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D009419:Nerve Tissue Proteins / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors; D015996:Survival Rate
D015415:Biomarkers; D009419:Nerve Tissue Proteins; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain