Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy.
Pain arises from numerous causes in cancer patients. Well known to cancer care providers, but perhaps less well so to others, is that the main causes of pain in cancer patients in fact arise due to cancer treatments more so than the disease itself. In this paper clinical and laboratory findings on the characteristics of chemotherapy-induced neuropathic pain are reviewed and a scheme for the underlying mechanisms is outlined.
Department of Anesthesiology and Pain Medicine, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA.
J P
JP
Cata
H R
HR
Weng
B N
BN
Lee
J M
JM
Reuben
P M
PM
Dougherty
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000633:toxicity; D001522:Behavior, Animal / Q000502:physiology; D006801:Humans; D010147:Pain Measurement; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology
D000970:Antineoplastic Agents