[Anlysis on features of dead cases with human Streptococcus suis infections].
OBJECTIVE
To describe the clinical and epidemiological features of dead cases with human Streptococcus suis infections, and to find the target population for preventing death and the related indicators.


METHODS
Epidemiological investigation on human Streptococcus suis infections was implemented used unified questionnaires. Analysis on dead cases and survival cases (as contrast) was done.


RESULTS
The population with highest fatality rate was in 40-49 age group. 97.37% of dead cases had toxic shock syndrome. The mean interval from onset to admission was 0.76 days, and the mean course was 2.11 days. The progression among dead cases was faster than that among survival cases. Chief clinical manifestations of dead cases that are more frequent than survival cases are purpura (73.68%), diarrhea (50.0%), dyspnea (21.05%), conjunctival congestion (34.21%), etc. Renal impairment and liver involvement in dead cases were more significant than that in survival cases. No significant difference between mean incubation period, exposure rates of main risk factors in dead cases and in survival cases was found.


CONCLUSIONS
Preventing toxic shock syndrome might reduce the fatality rate. The target population for preventing death is aged > or = 40. Liver function and renal function testing might be indicators for monitoring the progression of human Streptococcus suis infections.
Sichuan Provincial Center for Disease Control and Provention, Chengdu 610031, China.
Xiao-ping
XP
Zhu
Rong-qiang
RQ
Zu
Zhi-hai
ZH
Chen
Xue-cheng
XC
Liu
Lun-guang
LG
Liu
Wen-jun
WJ
Zhong
Shi-wen
SW
Wang
Ni-juan
NJ
Xiang
Heng
H
Yuan
Ling
L
Meng
Yang-bing
YB
Ou
Yong-jun
YJ
Gao
Qiang
Q
Lv
Yan
Y
Huang
Xiang-dong
XD
An
Ting
T
Huang
Xing-yu
XY
Zhou
Liao
L
Feng
Qi-di
QD
Pang
Wei-zhong
WZ
Yang
D000328:Adult; D000368:Aged; D002681:China; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013290:Streptococcal Infections / Q000097:blood / Q000382:microbiology* / Q000401:mortality* / Q000473:pathology; D017011:Streptococcus suis / Q000502:physiology*; D055815:Young Adult