Initial clinical testing of a holographic non-invasive contact lens glucose sensor.
BACKGROUND
The purpose of the present study was to determine the effectiveness of a new holographic contact lens glucose sensor for the non-invasive monitoring of blood glucose.


METHODS
One fasting normal subject was given an oral challenge consisting of 44 g of glucose. The contact lens hologram signal and fingerstick blood glucose were measured over a 26- min period.


RESULTS
The contact lens hologram signal appeared to track blood glucose well. The contact lens was comfortable and well tolerated.


CONCLUSIONS
The holographic contact lens glucose sensor shows promise as a non-invasive home glucose monitor.
CIBA Vision Corporation, Duluth, Georgia, USA.
Angelika
A
Domschke
Wayne F
WF
March
Satyamoorthy
S
Kabilan
Christopher
C
Lowe
D001786:Blood Glucose / Q000032:analysis*; D003261:Contact Lenses; D004784:Environmental Monitoring / Q000379:methods; D004867:Equipment Design; D005947:Glucose / Q000032:analysis*; D006696:Holography / Q000295:instrumentation / Q000379:methods*; D006801:Humans
D001786:Blood Glucose; D005947:Glucose