New palladium-catalyzed reaction pathway to the Erythrina skeleton.
Palladium-catalyzed arylation of alpha,beta-unsaturated gamma-lactam, which could be prepared by condensation of amines and keto-esters, has been carried out to make the core structure of Erythrina alkaloids.
Kim
Guncheol
G
Department of Chemistry, College of Natural Science, Chungnam National University, Taejon 305-764, Korea. guncheol@cnu.ac.kr
Kim
Jin Hee
JH
Lee
Ki Youn
KY
D000470:Alkaloids / Q000138:chemical synthesis*; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D004895:Erythrina / Q000737:chemistry*; D004952:Esters; D007659:Ketones / Q000737:chemistry; D007769:Lactams / Q000737:chemistry*; D008968:Molecular Conformation; D010165:Palladium / Q000737:chemistry*
D000470:Alkaloids; D000588:Amines; D004952:Esters; D007659:Ketones; D007769:Lactams; D010165:Palladium