Use of prophylactic antibiotics in a paediatric day-case surgery at NAUTH, Nnewi, Nigeria: a randomized double-blinded study.
This was a randomized double-blinded study to assess the need for prophylactic antibiotics in paediatric day-case surgery, as well as the cost implication. Group A received preoperative intravenous ampiclox and vitamin B complex in doses appropriate for weight and age, while group B received only vitamin B complex as a placebo. The study was completed by 138 (95.2%) patients in group A, and by 140 (97.2%) patients in group B. Wound infection was seen in seven (5%) patients in group A and six (4.3%) patients in group B. The average cost of hernia repair in group A was US 43 dollars and US 31.1 dollars in group B.
Paediatric Surgery Unit, Department of Surgery, NAUTH, PMB 5025, Nnewi, Nigeria. dranosuigwe@yahoo.com
A N
AN
Osuigwe
C N
CN
Ekwunife
C H
CH
Ihekowba
D000556:Ambulatory Surgical Procedures / Q000009:adverse effects* / Q000191:economics; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D002648:Child; D004311:Double-Blind Method; D005260:Female; D006552:Hernia, Inguinal / Q000191:economics; D006801:Humans; D008297:Male; D009549:Nigeria; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents