Caged gene-inducer spatially and temporally controls gene expression and plant development in transgenic Arabidopsis plant.
Two new types of caged gene-inducers, caged 17beta-estradiol and caged dexamethazone, were synthesized. Caged gene-inducers were applied to transgenic Arabidopsis plants carrying a steroid hormone-inducible transactivation system. Light uncaged caged gene-inducers and controlled spatial and temporal expression of transgene in the transgenic plant. Furthermore, caged gene-inducers enabled the control of root development by light.
Hayashi
Ken-ichiro
K
Department of Biochemistry, Okayama University of Science, 1-1 Ridai-cho, Okayama City 700-0005, Japan. hayashi@dbc.ous.ac.jp
Hashimoto
Kazuya
K
Kusaka
Naoyuki
N
Yamazoe
Atsushi
A
Fukaki
Hidehiro
H
Tasaka
Masao
M
Nozaki
Hiroshi
H
D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development* / Q000528:radiation effects; D003907:Dexamethasone / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D004958:Estradiol / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects* / Q000528:radiation effects; D018506:Gene Expression Regulation, Plant / Q000187:drug effects* / Q000528:radiation effects; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D030821:Plants, Genetically Modified / Q000187:drug effects / Q000528:radiation effects; D013329:Structure-Activity Relationship; D014466:Ultraviolet Rays
C511139:1-(2-nitrophenyl)ethylcarbonyl imidazole; D007093:Imidazoles; D009574:Nitro Compounds; D004958:Estradiol; D003907:Dexamethasone