Our method of povidone-iodine ointment and gauze dressings reduced catheter-related infection in serious cases.
In experiment 1, we evaluated our method of catheter care at subclavian vein insertion sites for the control of catheter-related infections in seriously ill neurosurgical patients who needed prolonged catheter placement, compared with an older method. In our method, the insertion site was prepared with 10% povidone-iodine solution, followed by application of 10% povidone-iodine ointment, and covered with sterile gauze and a transparent polyurethane dressing. The older method was based on 1996 guidelines for the prevention of intravascular device-related infections. Catheter colonization and mortality were both found to be significantly reduced with our method (p = 0.0214, p = 0.0379, respectively). In experiment 2, we evaluated whether a regimen of catheter care with 10% povidone-iodine ointment was more effective than that without povidone-iodine ointment for the prevention of infections. This suggested effectiveness of 10% povidone-iodine ointment for reduction of infection. Our method of catheter care was useful even in seriously ill neurosurgical patients.
Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan. fukunaga@sc.itc.kei.ac.jp
Atsushi
A
Fukunaga
Heiji
H
Naritaka
Raita
R
Fukaya
Masanao
M
Tabuse
Tsuneo
T
Nakamura
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000150:complications / Q000382:microbiology / Q000517:prevention & control*; D001458:Bandages; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects / Q000382:microbiology; D003428:Cross Infection / Q000150:complications / Q000382:microbiology / Q000517:prevention & control*; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications / Q000601:surgery; D019635:Neurosurgical Procedures; D009824:Ointments; D011206:Povidone-Iodine / Q000008:administration & dosage*; D017592:Skin Care / Q000379:methods; D012996:Solutions; D013350:Subclavian Vein
D000891:Anti-Infective Agents, Local; D009824:Ointments; D012996:Solutions; D011206:Povidone-Iodine