Identification and localisation of the NR1 sub-unit homologue of the NMDA glutamate receptor in the honeybee brain.
The NR1 sub-unit homologue of the NMDA glutamate receptor was characterised in the honeybee. Sequence analysis suggests that the honeybee NMDA receptor may act as a coincidence detector molecule similar to its counterpart in the mammalian nervous system. The localisation of the expression sites at the mRNA and the protein levels indicates that the receptor is expressed throughout the brain, in neurons and in glial cells.
Freie Universität Berlin, Neurobiologie, Königin-Luise-Strasse 28/30, 14195 Berlin, Germany.
Mst Thangima
MT
Zannat
Fernando
F
Locatelli
Jürgen
J
Rybak
Randolf
R
Menzel
Gérard
G
Leboulle
D000595:Amino Acid Sequence; D000818:Animals; D001516:Bees / Q000378:metabolism*; D001921:Brain / Q000378:metabolism; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D021122:Protein Subunits / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics / Q000378:metabolism*
C409466:NR1 NMDA receptor; D021122:Protein Subunits; D012333:RNA, Messenger; D016194:Receptors, N-Methyl-D-Aspartate