A new stilbene glycoside from Dryopteris sublaeta.
OBJECTIVE
To study the chemical constituents of Dryopteris sublaeta Ching et Hsu.


METHODS
Fresh plant of Dryopteris sublaeta ching et hsu was extracted twice with boiling water, concentrated to small volume under reduced pressure at 50 degrees C. The concentrated material was partitioned with ether, ethyl acetate, and n-butanol. The fraction of ethyl acetate extract was chromatographed over macroporous adsorption resin (Diaion HP-20) eluted with a mixture of H2O and MeOH in increasing MeOH content. Their fractions from resin were repeatedly chromatographed over Toyopearl HW-40, Sephadex LH-20 and silica gel column chromatography. The compounds were identified on the basis of their physiochemical and spectral data.


RESULTS
Four compounds were obtained and identified as 3,5-dihydroxy-stilbene-3-O-neohesperidoside (1), 3,5-dihydroxy-stilbene-3-O-beta-D-glucoside (2), polydotin peceid (3) and 3,5,4'-trihydroxy-bibenzyl-3-O-beta-D-glucoside (4).


CONCLUSIONS
Compound 1 is a new compound, the others were isolated from Dryopteris for the first time.
Feng
Wei-sheng
WS
Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. fwsh@hactcm.edu.cn
Cao
Xin-wei
XW
Kuang
Hai-xue
HX
Zheng
Xiao-ke
XK
D032492:Dryopteris / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification*
C521173:3,5-dihydroxy-stilbene-3-O-neohesperidoside; D006027:Glycosides; D013267:Stilbenes