Surgery for thyroid Hürthle cell tumours--a single institution experience.
OBJECTIVE
The objective of the study was to report a series of patients with Hürthle cell tumours.


METHODS
We reviewed medical records of single institution from January 1982 to December 2002, including follow-up information.


RESULTS
We identified 199 patients with Hürthle cell tumours (HCT), 88 patients with Hürthle cell carcinoma (HCC) and 111 patients with Hürthle cell adenoma (HCA). The HCC group had significantly longer duration of the disease and larger tumours (4.8 vs 3.8 cm) compared with HCA group. Gender appeared to play significant role in patients with HCT (women outnumbered man by 7:1; p < 0.01). Surgical management for 80% of patients with HCA consisted of hemithyroidectomy and total thyroidectomy in 87% patients in the HCC group. Temporary laryngeal nerve palsy and temporary hypoparathyroidismus were not seen in HCA group, in HCC group were confirmed in 2.27 and 3.41%, respectively. Four patients with HCC relapsed and two died of HCC.


CONCLUSIONS
HCC has outlook for favorable outcome when treated radically with total thyroidectomy.
Center for Endocrine Surgery, Institute of Endocrinology, Clinical Center of Serbia, Dr Subotica 13, Belgrade, Serbia and Montenegro. kipaun@eunet.yu
I
I
Paunovic
K
K
Krgovic
S
S
Tatic
A
A
Diklic
V
V
Zivaljevic
N
N
Kalezic
M
M
Havelka
D018249:Adenoma, Oxyphilic / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D017678:Sex Distribution; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D016896:Treatment Outcome