Development of specific immunoglobulin Ga (IgGa) and IgGb antibodies correlates with control of parasitemia in Babesia equi Infection.
In this study, the kinetics of specific immunoglobulin G (IgG) isotypes were characterized in Babesia equi (Theileria equi)-infected horses. IgGa and IgGb developed during acute infection, whereas IgG(T) was detected only after resolution of acute parasitemia. The same IgG isotype profile induced during acute infection was obtained by equi merozoite antigen 1/saponin immunization.
Cunha
Cristina W
CW
Washington State University, Department of Veterinary Microbiology and Pathology, Pullman, WA 99164-7040, USA. cwcunha@vetmed.wsu.edu
McGuire
Travis C
TC
Kappmeyer
Lowell S
LS
Hines
Stephen A
SA
Lopez
A Marianela
AM
Dellagostin
Odir A
OA
Knowles
Donald P
DP
D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis*; D001403:Babesia / Q000276:immunology*; D001404:Babesiosis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay; D006734:Horse Diseases / Q000276:immunology* / Q000469:parasitology; D006736:Horses; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000145:classification; D007132:Immunoglobulin Isotypes / Q000096:biosynthesis; D018512:Parasitemia / Q000276:immunology / Q000469:parasitology / Q000662:veterinary; D013997:Time Factors
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007132:Immunoglobulin Isotypes