[Buerger's disease (thromboangiitis obliterans)].
Thromboangiitis obliterans (TAO) is a segmental, inflammatory, vasoocclusive disease that predominantly affects the small and medium-sized arteries and veins of the extremities. It most often occurs in young male smokers, especially those from Mediterranean and Asian countries. It is considered an autoimmune process related to the use of tobacco products. Clinically, it is characterized by the presence of painful, ischemic ulcers of the digits. Histopathological studies usually show an occlusive intraluminal thrombus with a predominantly acute inflammatory infiltrate. To make the diagnosis, it is important to exclude other causes of ischemia of the extremities, and different authors have proposed criteria to establish this diagnosis. Treatment is only effective if it is accompanied by abstention from tobacco. There are also different pharmacological and surgical strategies for its management.
Goiriz-Valdés
Rebeca
R
Departamento de Dermatología, Hospital Universitario de La Princesa, Madrid, Spain. rebecagv@aedv.es
Fernández-Herrera
Jesús
J
D006801:Humans; D013919:Thromboangiitis Obliterans / Q000175:diagnosis / Q000628:therapy