Evaluation of disk diffusion method for determining posaconazole susceptibility of filamentous fungi: comparison with CLSI broth microdilution method.
The disk diffusion method was evaluated for determining posaconazole susceptibility against 78 strains of molds using two culture media in comparison with the CLSI (Clinical Laboratory Standards Institute) broth microdilution method (M38-A). A significant correlation between disk diffusion and microdilution methods was observed with both culture media.
S. Microbiología, U. Investigación, Valme University Hospital, Seville, Spain.
E
E
López-Oviedo
A I
AI
Aller
C
C
Martín
C
C
Castro
M
M
Ramirez
J M
JM
Pemán
E
E
Cantón
C
C
Almeida
E
E
Martín-Mazuelos
D000935:Antifungal Agents / Q000494:pharmacology*; D003470:Culture Media; D005069:Evaluation Studies as Topic; D005658:Fungi / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods* / Q000592:standards*; D012044:Regression Analysis; D014230:Triazoles / Q000494:pharmacology*
D000935:Antifungal Agents; D003470:Culture Media; D014230:Triazoles; C101425:posaconazole