[Metabolic control by means of insulin in patients with type 2 diabetes and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity--secondary publication].
Patients with diabetes have an unfavourable prognosis after an acute myocardial infarction. The DIGAMI 2 study investigated the effect of various metabolic treatment strategies in type 2 diabetic patients with acute myocardial infarction: acutely introduced, long-term insulin treatment did not improve survival when compared with conventional management at similar levels of glucose control. However, good glucose control seems important since the glucose level was found to be a strong predictor of long-term mortality in this patient category.
Gustafsson
Ida
I
H:S Frederiksberg Hospital, Kardiologisk-endokrinologisk Klinik E, DK-2000 Frederiksberg. gustafsson@dadlnet.dk
Malmberg
Klas
K
Rydén
Lars
L
Wedel
Hans
H
Birkeland
Kåre
K
Bootsma
Aart
A
Dickstein
Kenneth
K
Efendic
Suad
S
Fisher
Miles
M
Hamsten
Anders
A
Herlitz
Johan
J
Hildebrandt
Per Rossen
PR
MacLeod
Kenneth
K
Laakso
Markku
M
Torp-Pedersen
Christian T
CT
Waldenström
Anders
A
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D011379:Prognosis
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin