Morphology evaluation of primary enamel exposed to antihistamine and fluoride dentifrice--an in vitro study.
This in vitro study sought to evaluate the action of a pediatric medication with low pH and high acidity in primary enamel submitted (or not) to daily applications of fluoride dentifrice. For this study, 70 blocks of primary molars (n = 10 per subgroup) were analyzed using scanning electron microscopy. Six subgroups (two control and four experimental) were submitted to different treatments for 10 days. Microscopically, the enamel blocks of the subgroups that received medication and fluoride demonstrated the largest areas of partially or totally conditioned superficial enamel. The opposite was observed in the subgroups that were not exposed to fluoride; erosions in the internal enamel and in the transition zone between deep enamel and dentine showed superior percentiles. It was concluded that the medication modified the morphology of the primary enamel and that the use of fluoride was able to reduce the erosive effect of the formulation.
Post Graduate Program in Dentistry, Federal University of Santa Catarina, Florianopolis, SC, Brazil.
Covolo Carolina
CC
da Costa
Izabel Cristina Santos
IC
Almeida
Luiz Cesar
LC
da Costa Filho
Hugo Mitsuo Silva
HM
Oshima
D002327:Cariostatic Agents / Q000494:pharmacology; D003743:Dental Enamel / Q000187:drug effects* / Q000648:ultrastructure; D003747:Dental Enamel Solubility; D003802:Dentifrices / Q000494:pharmacology; D005459:Fluorides / Q000494:pharmacology; D039563:Histamine H1 Antagonists, Non-Sedating / Q000009:adverse effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017336:Loratadine / Q000009:adverse effects*; D008855:Microscopy, Electron, Scanning; D008963:Molar; D018709:Statistics, Nonparametric; D017001:Tooth Demineralization / Q000517:prevention & control; D014077:Tooth Erosion / Q000139:chemically induced* / Q000517:prevention & control; D014094:Tooth, Deciduous / Q000187:drug effects*
D002327:Cariostatic Agents; D003802:Dentifrices; D039563:Histamine H1 Antagonists, Non-Sedating; D017336:Loratadine; D005459:Fluorides