QSAR study of mosquito repellents using Codessa Pro.
Protection times provided by 31 synthetic repellents against Aedes aegypti mosquitoes were correlated with the chemical structures of these repellents using Codessa Pro software. Two statistically significant quantitative models with R2 values of ca. 0.80 are presented and discussed.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611, USA. katritzky@chem.ufl.edu
Dobchev
Dimitar A
DA
Tulp
Indrek
I
Karelson
Mati
M
Carlson
David A
DA
D000818:Animals; D001733:Bites and Stings / Q000517:prevention & control*; D009033:Culicidae / Q000187:drug effects*; D007302:Insect Repellents / Q000494:pharmacology* / Q000627:therapeutic use; D021281:Quantitative Structure-Activity Relationship; D012984:Software
D007302:Insect Repellents