Asymmetry analysis of the retinal nerve fiber layer thickness in normal eyes using optical coherence tomography.
OBJECTIVE
To investigate the asymmetry of the retinal nerve fiber layer thickness (RNFLT) with respect to the horizontal and vertical meridian and between the right and left eye in normal subjects.


METHODS
The RNFLT was measured in 121 normal volunteers by optical coherence tomography (OCT). The RNFLT was analyzed by dividing the circle scanning area (diameter 3.4 mm) around the optic disc into 4 quadrants and 12 sectors.


RESULTS
There was a significant difference between the RNFLT of the nasal and temporal quadrant in individual eyes. There was a significant difference between the RNFLT of corresponding sectors with respect to the vertical or horizontal meridian in individual eyes. The nasal and temporal RNFLTs were asymmetrical between the right and left eye in the quadrant and sector analysis. The RNFLT of the nasal and temporal quadrant was thicker in the right eye. The nasal and inferior RNFLT measured by OCT had a significant correlation with degree of refractive error.


CONCLUSIONS
In normal subjects without significant anisometropia, there was significant asymmetry of the RNFLT for each eye as well as between the right and left eye.
Cheil Eye Hospital, Daegu, Korea.
Joon Jeong
JJ
Park
Dong Ryeul
DR
Oh
Sung Pyo
SP
Hong
Kyoo Won
KW
Lee
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000648:ultrastructure*; D009898:Optic Disk / Q000166:cytology; D012016:Reference Values; D012160:Retina / Q000166:cytology*; D012165:Retinal Ganglion Cells / Q000648:ultrastructure*; D041623:Tomography, Optical Coherence