Effect of a carbamide peroxide bleaching gel containing calcium or fluoride on human enamel surface microhardness.
This in vitro study evaluated the surface microhardness of human enamel submitted to bleaching with 10% carbamide peroxide (CP) containing calcium or fluoride. Ninety-eight dental blocks (5 x 5 mm2) with polished enamel surfaces were randomly assigned to 7 treatment groups (n=14), as follows: without bleaching and storage in artificial saliva (control); 10% CP; 10% CP + 0.05% calcium; 10% CP + 0.1% calcium; 10% CP + 0.2% calcium; 10% CP + 0.2% fluoride; and 10% CP + 0.5% fluoride. During 14 days, enamel surfaces were daily exposed to a 6-h bleaching regimen followed by storage in artificial saliva. Surface microhardness was measured before (baseline), during (7th day), immediately after bleaching (14th day) and 1 week post bleaching. Data were analyzed by two-way ANOVA and Tukey's test (p<0.05). All treatments reduced SM significantly during the bleaching cycle (7th day), immediately after bleaching (14th day) and 1 week post bleaching, compared to baseline and to the unbleached control group. In conclusion, in spite of the addition of calcium and fluoride, all bleaching treatments affected the enamel surface microhardness.
Department of Restorative Dentistry, Faculty of Dentistry of Piracicaba, Sate University of Campinas (UNICAMP), SP, Brazil.
Rogério
R
de Oliveira
Adriana Franco
AF
Paes Leme
Marcelo
M
Giannini
D002118:Calcium / Q000627:therapeutic use*; D000077463:Carbamide Peroxide; D002327:Cariostatic Agents / Q000627:therapeutic use*; D003743:Dental Enamel / Q000033:anatomy & histology / Q000187:drug effects*; D004338:Drug Combinations; D005459:Fluorides / Q000627:therapeutic use*; D006244:Hardness; D006801:Humans; D006863:Hydrogen-Ion Concentration; D016877:Oxidants / Q000627:therapeutic use*; D010545:Peroxides / Q000627:therapeutic use*; D012464:Saliva, Artificial / Q000737:chemistry; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods*; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
D002327:Cariostatic Agents; D004338:Drug Combinations; D016877:Oxidants; D010545:Peroxides; D012464:Saliva, Artificial; D000077463:Carbamide Peroxide; D014508:Urea; D005459:Fluorides; D002118:Calcium