Dynamic mechanical studies of hydrolytic degradation in isotropic and oriented Maxon B.
Hydrolytic degradation studies have been undertaken on Maxon B, a bioresorbable block copolymer of polyglycolic acid (PGA) and polytrimethylene carbonate (TMC). Isotropic and oriented samples were studied by dynamic mechanical measurements over a wide range of temperatures. In addition to mechanical tests, water content and mass loss were also determined on the degraded samples. At early stages of degradation water content was the dominant factor and plasticisation lead to reductions in the glass transition temperatures of the PGA and TMC components. Orientation was shown to give significant improvements in the mechanical properties, including overall increases in modulus and an increase in the glass transition temperature of the PGA component, which is important for the behaviour at body temperature (37 degrees C). Oriented samples also showed significantly less reduction in mechanical properties on degradation. Simple one-dimensional Takayanagi models were used to provide useful insight into the understanding of the mechanical behaviour.
Hill
Stuart P
SP
IRC in Polymer Science and Technology, School of Physics and Astronomy, University of Leeds, Leeds, LS2 9JT, UK.
Montes de Oca
Horacio
H
Klein
Phil G
PG
Ward
Ian M
IM
Rose
John
J
Farrar
David
D
D001672:Biocompatible Materials / Q000737:chemistry*; D001831:Body Temperature; D002021:Buffers; D004146:Dioxanes / Q000737:chemistry*; D004548:Elasticity; D005898:Glass; D006358:Hot Temperature; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008422:Materials Testing; D011100:Polyglycolic Acid / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013314:Stress, Mechanical; D013696:Temperature; D013718:Tensile Strength; D013997:Time Factors; D014867:Water
D001672:Biocompatible Materials; D002021:Buffers; D004146:Dioxanes; D011108:Polymers; D014867:Water; D011100:Polyglycolic Acid; C059299:polytrimethylene carbonate; C046409:polyglyconate