Analysis of a hepatitis C screening programme for US veterans.
This study analyses a screening programme for hepatitis C virus (HCV) infection among US veterans in a suburban Veterans Affairs Medical Center, in New York. This is the first study examining all 11 potential risk factors listed in the 2001 National U.S. Veterans Health Administration Screening Guidelines. A retrospective study was conducted of 5400 veterans 'at risk' of HCV, identified through a questionnaire in this institution's primary-care outpatient departments between 1 October 2001 and 31 December 2003. Multivariate logistic regression models were built to identify independent predictors of infection. Of 2282 veterans tested for HCV, 4.6% were confirmed by HCV PCR to be HCV infected. In the multivariate model developed, injection drug use, blood transfusion before 1992, service during the Vietnam era, tattoo, and a history of abnormal liver function tests were independent predictors of HCV infection. Our data support considering a more targeted screening approach that includes five of the 11 risk factors.
Zuniga
I A
IA
Department of Preventive Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
Chen
J J
JJ
Lane
D S
DS
Allmer
J
J
Jimenez-Lucho
V E
VE
D000328:Adult; D000368:Aged; D001803:Blood Transfusion; D005260:Female; D006306:Health Surveys; D006526:Hepatitis C / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D015999:Multivariate Analysis; D009518:New York; D012189:Retrospective Studies; D012307:Risk Factors; D015819:Substance Abuse, Intravenous; D013653:Tattooing; D014481:United States; D014728:Veterans; D047829:Vietnam Conflict