Disseminate and fatal cytomegalovirus disease with thymitis in a naive HIV-patient after early initiation of HAART: immune restoration disease?
We describe a naive HIV-infected patient who developed a Pneumocystis carinii pneumonia and disseminate and fatal cytomegalovirus disease within 3 months after initiation of HAART, suggesting due to coincidence in time, an immune restoration disease. We propose an alternative hypothesis.
Gutiérrez
Sonia
S
Department of Internal Medicine, Virgen del Rocio University Hospital, Seville, Spain.
Alconchel
Silvia
S
Ruiz-Mateos
Ezequiel
E
Genebat
Miguel
M
Vallejo
Alejandro
A
Lissen
Eduardo
E
Fernández-Alonso
Jorge
J
Leal
Manuel
M
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology* / Q000821:virology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D003586:Cytomegalovirus Infections / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007150:Immunohistochemistry; D007181:Inclusion Bodies, Viral / Q000378:metabolism; D008168:Lung / Q000821:virology; D008482:Mediastinum / Q000000981:diagnostic imaging; D008590:Meningoencephalitis / Q000473:pathology; D011020:Pneumonia, Pneumocystis / Q000276:immunology*; D012367:RNA, Viral / Q000097:blood; D011859:Radiography; D011948:Receptors, Antigen, T-Cell / Q000032:analysis; D013950:Thymus Gland / Q000821:virology; D013997:Time Factors; D019562:Viral Load
D012367:RNA, Viral; D011948:Receptors, Antigen, T-Cell