A primary culture system for human odontoblasts.
Caries is one of the most prevalent of all human diseases. In recent years there has been a growing recognition that healing or remineralization protocols for the treatment of carious lesions in dentine are possible, rather than just relying on surgical removal of the diseased tissue and placement of restorative materials. This project proposes to investigate a strategy for deliberately stimulating cellular reparative processes for the treatment of this disease. In order to do this, it is necessary to develop a cell culture system to develop and characterize the mineralizing cells (odontoblast like) from human dental explants.
Scott
Juliette M
JM
Biomaterials Research Unit, Department of Biomedical Engineering, University of Sydney, Australia.
Swain
Michael
M
Mason
Rebecca
R
D018929:Cell Culture Techniques / Q000379:methods*; D003782:Dental Pulp / Q000166:cytology*; D006801:Humans; D009804:Odontoblasts / Q000166:cytology*; D014094:Tooth, Deciduous / Q000166:cytology