Recombinant human bone morphogenic protein-7: applications for clinical trauma.
Several clinical trials have examined the safety and efficacy of recombinant human bone morphogenic protein-7 (rhBMP-7) for osseous repair in clinical trauma. This article summarizes the results obtained from three recent clinical trials, which suggest that rhBMP-7 is useful in the treatment of tibial nonunion, long bone nonunion, and open tibial shaft fractures.
McKee
Michael D
MD
St. Michael's Hospital, Toronto, Ontario, Canada. McKeeM@smh.toronto.on.ca
D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use*; D017102:Fracture Healing / Q000187:drug effects*; D005599:Fractures, Ununited / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D011859:Radiography; D016032:Randomized Controlled Trials as Topic; D011994:Recombinant Proteins / Q000627:therapeutic use; D013978:Tibial Fractures / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery
D019485:Bone Morphogenetic Proteins; D011994:Recombinant Proteins