The metabolic syndrome in women: a growing problem for cardiac risk.
The risk of developing cardiovascular disease has recently been associated with a set of metabolic and physiological risk factors that include abdominal obesity, atherogenic dyslipidemia, hypertension, and elevated plasma glucose. The term most commonly used to describe this conglomeration of risk factors is the metabolic syndrome. Coronary heart disease risk is tripled in those individuals with this syndrome. Primary treatment focuses on weight reduction and physical activity to reduce risk factors and prevent the progression to cardiovascular disease. This article will review the definition, prevalence, pathogenesis, and treatment of the metabolic syndrome in women and will discuss the role of polycystic ovarian syndrome in relation to the metabolic syndrome.
Heart Function Clinic, Western Piedmont Heart Centers, 1771 Tate Boulevard SE, Suite 201, Hickory, NC 28602, USA. smcpaul@earthlink.net
Sara
S
Paul
Lanna
L
Smith
D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D009765:Obesity / Q000503:physiopathology; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D015995:Prevalence; D012307:Risk Factors