MicroRNA: microRNAs reach out into dendrites.
A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Division of Chemistry and Chemical Engineering, California Institute of Technology, 164-30, Pasadena, California 91125, USA.
Hwan-Ching
HC
Tai
Erin M
EM
Schuman
D003712:Dendrites / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000502:physiology; D054461:Lim Kinases; D035683:MicroRNAs / Q000378:metabolism / Q000502:physiology*; D014176:Protein Biosynthesis / Q000502:physiology; D011494:Protein Kinases / Q000378:metabolism
D035683:MicroRNAs; D011494:Protein Kinases; D054461:Lim Kinases