[Eccrine squamous syringometaplasia from chemotherapy extravasation].
Eccrine squamous syringometaplasia is a rare entity that occurs in patients who have received chemotherapy treatment. It also occurs in association with chronic ulcers, skin tumors, and after the ingestion of drugs, exposure to toxic agents and inflammatory processes. We present the case of a 47-year-old male diagnosed with microcytic lung carcinoma and superior vena cava syndrome. After receiving the third cycle of chemotherapy, and after accidental extravasation, he presented with an erythematous plaque. The histopathological study revealed eccrine squamous syringometaplasia together with interphase dermatitis and epidermal changes that may be responsible for the epidermal necrosis.
Bordel
María Teresa
MT
Servicio de Dermatología, Hospital Clínico Universitario de Valladolid, Facultad de Medicina de Valladolid, Spain. matebordel@yahoo.es
Miranda
Alberto
A
D000970:Antineoplastic Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D004439:Eccrine Glands / Q000473:pathology*; D006801:Humans; D008297:Male; D008679:Metaplasia / Q000139:chemically induced; D008875:Middle Aged; D013543:Sweat Gland Diseases / Q000139:chemically induced*
D000970:Antineoplastic Agents