[Topical treatment of melanoma skin metastases with imiquimod].
The treatment of skin metastases of melanoma can be difficult in many cases because of the patients age, as well as the number, size and location of the lesions. We present the case of an 82-year-old male with melanoma skin metastases on the scalp, which responded satisfactorily to treatment with 5 % imiquimod cream. Imiquimod is a topical immunomodulator with antiviral and antineoplastic action. This case, along with others that have recently been published, supports the usefulness of this treatment in selected cases of melanoma skin metastases, at least for palliative purposes.
Servicios de Dermatología, Hospital Universitario La Paz, Valle de Bergantiños 23, B-B, 28039 Madrid, Spain. mmss@wanadoo.es
Mercedes
M
Sigüenza
Angel
A
Pizarro
Matías
M
Mayor
Carmen
C
Vidaurrázaga
Lara
L
Miralles
María
M
González-Beato
Mariano
M
Casado
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D000634:Aminoquinolines / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000556:secondary*; D012535:Scalp; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000556:secondary*
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod