Nondisjunction rates of mouse chromosomes involved in heterozygous Rb rearrangements measured by chromosome painting of spermatocytes. II. The effects of trivalent combinations and genetic background.
Chromosome specific nondisjunction rates were quantified by dual-colour FISH in spermatocytes II of Robertsonian heterozygous mice with different trivalent combinations or, alternatively, with different genetic backgrounds. We found that such factors do not influence the proneness to nondisjunction of specific chromosomes.
Department of Biology, University of Rome Tor Vergata, Rome, Italy. m.scascitelli@inwind.it
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Scascitelli
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Gustavino
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Pacchierotti
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Spirito
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Rizzoni
D000818:Animals; D002874:Chromosome Mapping; D020223:Chromosome Painting; D003433:Crosses, Genetic; D005260:Female; D005298:Fertility; D015321:Gene Rearrangement; D006580:Genetic Carrier Screening; D007621:Karyotyping; D008297:Male; D051379:Mice; D009630:Nondisjunction, Genetic; D011995:Recombination, Genetic; D016160:Retinoblastoma Protein / Q000235:genetics*; D013090:Spermatocytes / Q000473:pathology / Q000502:physiology*
D016160:Retinoblastoma Protein