[An in vitro study of cholesterol-lowering properties of probiotics isolated from the human feces].
21 strains of Lactobacillus and Bifidobacterium, isolated from feces of healthy youth and children feces and identified by molecular biological methods, together with 6 strains of probiotics preserved in Onlly lab were studied in the experiments, including removal cholesterol from media, bile-tolerance and acid-tolerance. The results demonstrated that all strains could remove cholesterol from media and removal rates of 5 strains were more than 40%. Meanwhile these 5 strains had high removal effectiveness. The bile-tolerance and acid-tolerance were varied from strain to strain. Among 27 strains, Bm26 demonstrated higher ability of removal cholesterol, bile-tolerance and bile-tolerance than other strains.
College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China. jerress_zhao@yahoo.com.cn
Jia-Rui
JR
Zhao
Xiao-Bing
XB
Fan
Xiao-Min
XM
Hang
Yi-Ming
YM
Wang
Hong
H
Yang
D000293:Adolescent; D000924:Anticholesteremic Agents / Q000494:pharmacology*; D001644:Bifidobacterium / Q000187:drug effects / Q000502:physiology*; D001647:Bile Acids and Salts / Q000494:pharmacology; D002648:Child; D005243:Feces / Q000382:microbiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000187:drug effects / Q000502:physiology*; D008297:Male; D019936:Probiotics / Q000494:pharmacology*
D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts