An event-related fMRI study of the neural networks underlying repetition suppression and reaction time priming in implicit visual memory.
Unfamiliar line drawings were presented to subjects three times during BOLD fMRI scanning. A set of brain areas was detected in which the effect of stimulus repetition on the evoked fMRI response depended on whether or not the drawing could be conceived as a coherent three-dimensional structure. Differential repetition effects were found in the neural response to drawings of both structurally possible and impossible objects. This differential effect of repetition was related to the amount of reaction time priming on the concurrent task involving decisions about three-dimensional structure in the possible but not in the impossible objects. These results point to different neurophysiological processing mechanisms for structurally possible and impossible images and demonstrate neural plasticity that predicts behavioral priming for structurally possible images.
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, 622 West 168th Street, PH-18, New York, NY 10039, USA. ch629@columbia.edu
Christian
C
Habeck
H John
HJ
Hilton
Eric
E
Zarahn
Truman
T
Brown
Yaakov
Y
Stern
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008568:Memory / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*