Antibacterial and cytotoxic xanthones from the roots of Cratoxylum formosum.
Chemical investigation of the roots of Cratoxylum formosum has resulted in the isolation and characterization of xanthones: three new, named formoxanthone A-C and three known together with three known anthraquinones. Their structures were established on the basis of analysis of spectroscopic evidence. In addition, antibacterial and cytotoxic activities of the isolates were also evaluated.
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.
Sompong
S
Boonsri
Chatchanok
C
Karalai
Chanita
C
Ponglimanont
Akkharawit
A
Kanjana-opas
Kan
K
Chantrapromma
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D028084:Clusiaceae / Q000737:chemistry*; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal; D018675:Toxicity Tests; D014407:Tumor Cells, Cultured; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D044004:Xanthones; C511826:formoxanthone A; C511827:formoxanthone B; C511828:formoxanthone C