[Toxic epidermal necrolysis caused by lamotrigine].
Toxic epidermal necrolysis (TEN) is a serious entity consisting of a generalized eruption with the formation of flaccid blisters. It affects at least 30 % of the cutaneous surface and is usually related to the prior ingestion of medications. We describe TEN symptoms related to the introduction of lamotrigine, an anti-epileptic drug prescribed in this case for the prevention of migrainous episodes.
Rodríguez-Blanco
Isabel
I
Servicio de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, San Francisco s/n, 15782 Santiago de Compostela, Spain. mejaime@usc.es
Sánchez-Aguilar
Dolores
D
Toribio
Jaime
J
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000077213:Lamotrigine; D013262:Stevens-Johnson Syndrome / Q000209:etiology*; D014227:Triazines / Q000009:adverse effects*
D000927:Anticonvulsants; D014227:Triazines; D000077213:Lamotrigine