Therapeutic hypothermia following perinatal asphyxia.
Well constructed and carefully analysed trials of hypothermic neural rescue therapy for infants with neonatal encephalopathy have recently been reported. The data suggest that either selective head cooling or total body cooling reduces the combined chance of death or disability after birth asphyxia. However, as there are still unanswered questions about these treatments, many may still feel that further data are needed before health care policy can be changed to make cooling the standard of care for all babies with suspected birth asphyxia.
Division of Clinical Sciences, Faculty of Medicine, Imperial College London, UK. David.Edwards@imperial.ac.uk
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D001238:Asphyxia Neonatorum / Q000150:complications*; D002658:Developmental Disabilities / Q000517:prevention & control; D019317:Evidence-Based Medicine; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D020925:Hypoxia-Ischemia, Brain / Q000209:etiology / Q000628:therapy*; D007231:Infant, Newborn