[Effect of hypokinetic stress and low intensity electromagnetic field of extremely high frequency on changes of cytokine concentration in rat blood].
The influence of hypokinetic stress and low-intensive electromagnetic field of extremely high frequency (EMF of EHF) on cytokine concentration changes (IL-1, 2, 4, 6 and TNF-6) in serum of rats was investigated. Using an immunoenzyme method it was shown that the concentration of the investigated cytokines under influence of the hypokinetic stress and low-intensive EMF of EHF is changed in an inversed direction.. An isolated influence of EMF of EHF on animals resulted in significant decrease of IL- 1B concentration and in the tendency of IL-6 concentration reduction while concentration of IL-2, IL-4 and TNF-6 increased. Mobility restriction of animals has caused substantial growth of IL-1B, IL-2, IL-6 and TNF-6 concentration with simultaneous decrease of IL-4 concentration. Variation of the investigated parameters differed considerably from the results obtained for animals in the case of a restricted mobility, which does not take place under activity of EMF of EHF with the combined influence of hypokinesia activity and EMF of EHF. It is assumed that revealed changes of the cytokine profile after the use of low-intensive EMF of EHF resulted in increase of the nonspecific immunological reactivity level of animals that is very important component of its physiological action.
Chuian
O M
OM
Temur'iants
N A
NA
Makhonina
M M
MM
Zaiachnikova
T V
TV
D000818:Animals; D016207:Cytokines / Q000097:blood* / Q000276:immunology; D007107:Immune System / Q000528:radiation effects*; D008297:Male; D008872:Microwaves; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood / Q000276:immunology*
D016207:Cytokines