A note on QTL detecting for censored traits.
Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".
Fang
Yixin
Y
Department of Statistics, Columbia University, New York, NY 10027, USA. yf2113@columbia.edu
D002874:Chromosome Mapping; D003198:Computer Simulation; D008957:Models, Genetic; D040641:Quantitative Trait Loci