[Extensive Fournier gangrene. A dermatologic emergency].
Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men. The cause is a polymicrobial infection associated with superficial trauma, urological diseases and operations, as well as colorectal diseases. Diabetes mellitus, alcoholism, immunosuppression and other severe illnesses are frequent co-factors. Immediate administration of systemic broad-spectrum antibiotic therapy with coverage of both gram-positive and gram-negative bacteria combined with surgical debridement and intensive medical care can lower the high mortality rate of this condition.
Aschoff
R
R
Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden. Roland.Aschoff@mailbox.tu-dresden.de
Baldauf
A
A
Leike
S
S
Wirth
M P
MP
Meurer
M
M
D000328:Adult; D002439:Cefotaxime / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D004630:Emergencies; D005500:Follow-Up Studies; D018934:Fournier Gangrene / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009336:Necrosis; D010409:Penile Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012611:Scrotum / Q000473:pathology / Q000601:surgery; D012867:Skin / Q000473:pathology; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013297:Streptococcus pyogenes; D014031:Tobramycin / Q000627:therapeutic use
D008795:Metronidazole; D002439:Cefotaxime; D014031:Tobramycin