Advancing glycomics: implementation strategies at the consortium for functional glycomics.
Glycomics-an integrated approach to study structure-function relationships of complex carbohydrates (or glycans)-is an emerging field in this age of post-genomics. Realizing the importance of glycomics, many large scale research initiatives have been established to generate novel resources and technologies to advance glycomics. These initiatives are generating and cataloging diverse data sets necessitating the development of bioinformatic platforms to acquire, integrate, and disseminate these data sets in a meaningful fashion. With the consortium for functional glycomics (CFG) as the model system, this review discusses databases and the bioinformatics platform developed by this consortium to advance glycomics.
Raman
Rahul
R
Center for Biomedical Engineering, Massachusetts Institute of Technology; Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Venkataraman
Maha
M
Ramakrishnan
Subu
S
Lang
Wei
W
Raguram
S
S
Sasisekharan
Ram
R
D000818:Animals; D019295:Computational Biology; D030562:Databases, Protein; D023281:Genomics; D051379:Mice; D008822:Mice, Transgenic; D011134:Polysaccharides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D013329:Structure-Activity Relationship
D011134:Polysaccharides; D011506:Proteins