[Neutrophilic eccrine hidradenitis secondary to thioguanine in a neutropenic patient].
Neutrophilic eccrine hidradenitis (NEH) is an infrequent, self-limited inflammatory dermatosis characterized by a neutrophilic infiltrate around the eccrine glands. Clinically, it presents with different types of lesions. NEH occurs most frequently in patients who have undergone chemotherapy for hematologic neoplasms. We present a case of NEH in a 70-year-old neutropenic male who received thioguanine for acute myeloid leukemia. The erythematous plaques disappeared in 3-4 weeks. The histological findings were compatible with NEH. Skin cultures ruled out infectious causes.
Servicio de Dermatología, Hospital Universitario Reina Sofía de Córdoba, Spain. alonsobujaldon@yahoo.es
Alfonso
A
Rodríguez Bujaldon
Carmen
C
Vázquez
Rafael
R
Jiménez-Puya
Manuel
M
Galán
Antonio
A
Vélez
José C
JC
Moreno
Rafael
R
Rojas
Víctor
V
Arqueros
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D004439:Eccrine Glands; D016575:Hidradenitis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000150:complications*; D013866:Thioguanine / Q000009:adverse effects*
D000964:Antimetabolites, Antineoplastic; D013866:Thioguanine