[Epidemiology of chronic hepatitis B].
The prevalence of hepatitis B surface antigen (HBsAg) carriage in France is 0.68% and that of HBcAb 8.18%. Chronic hepatitis B is more frequent in subjects of low socioeconomic status and those receiving government health insurance for the needy (CMU). The prevalence of chronic hepatitis B that is HBeAg-positive is now 64.4%. Nearly 60% of these patients were not born in France. Patients with HBeAg-negative chronic hepatitis B are more likely to be older, male, and have cirrhosis; they also have lower levels of serum transaminase activity and HBV DNA than those with HBeAg-positive chronic hepatitis B.
Zarski
Jean-Pierre
JP
Département d'hépato-gastroentérologie, Unité Inserm U548, CHU de Grenoble. JPZarski@chu-grenoble.fr
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000032:analysis; D004641:Emigration and Immigration; D005260:Female; D005602:France / Q000453:epidemiology; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000235:genetics; D019694:Hepatitis B, Chronic / Q000201:enzymology / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012959:Socioeconomic Factors; D000637:Transaminases / Q000097:blood
D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens; D000637:Transaminases