Synthesis of novel quaternary chitosan derivatives via N-Chloroacyl-6-O-triphenylmethylchitosans.
Various quaternary chitosan derivative structures were synthesized by reacting N-chloroacyl-6-O-triphenylmethylchitosans with tertiary amines. Full substitutions were obtained from the quaternization reactions and the obtained water-soluble quaternary chitosan derivatives were thoroughly characterized with (1)H NMR, (13)C NMR, (1)H-(13)C HSQC NMR, and FT-IR.
Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland. Jukka.Holappa@uku.fi
Jukka
J
Holappa
Tapio
T
Nevalainen
Pasi
P
Soininen
Már
M
Másson
Tomi
T
Järvinen
D000588:Amines / Q000737:chemistry*; D002240:Carbohydrate Sequence; D002247:Carbon Isotopes; D048271:Chitosan / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011522:Protons; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013237:Stereoisomerism
D000588:Amines; D002247:Carbon Isotopes; D011522:Protons; D000644:Quaternary Ammonium Compounds; D048271:Chitosan