Optimal target search on a fast-folding polymer chain with volume exchange.
We study the search process of a target on a rapidly folding polymer ("DNA") by an ensemble of particles ("proteins"), whose search combines 1D diffusion along the chain, Lévy type diffusion mediated by chain looping, and volume exchange. A rich behavior of the search process is obtained with respect to the physical parameters, in particular, for the optimal search.
Lomholt
Michael A
MA
NORDITA, Blegdamsvej 17, Copenhagen Ø, Denmark.
Ambjörnsson
Tobias
T
Metzler
Ralf
R