[Extensive Fournier gangrene. A dermatologic emergency].
Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men. The cause is a polymicrobial infection associated with superficial trauma, urological diseases and operations, as well as colorectal diseases. Diabetes mellitus, alcoholism, immunosuppression and other severe illnesses are frequent co-factors. Immediate administration of systemic broad-spectrum antibiotic therapy with coverage of both gram-positive and gram-negative bacteria combined with surgical debridement and intensive medical care can lower the high mortality rate of this condition.
Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden. Roland.Aschoff@mailbox.tu-dresden.de
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D000328:Adult; D002439:Cefotaxime / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D004630:Emergencies; D005500:Follow-Up Studies; D018934:Fournier Gangrene / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009336:Necrosis; D010409:Penile Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012611:Scrotum / Q000473:pathology / Q000601:surgery; D012867:Skin / Q000473:pathology; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013297:Streptococcus pyogenes; D014031:Tobramycin / Q000627:therapeutic use
D008795:Metronidazole; D002439:Cefotaxime; D014031:Tobramycin