[Disc neovascularization in a patient with Vogt-Koyanagi-Harada disease and efficacy of steroid pulse therapy].
OBJECTIVE
To report a patient with Vogt-Koyanagi-Harada disease who developed neovascularization at the optic disc.


METHODS
A 19-year-old woman visited our hospital two months after becoming aware of fever, headache, tinnitus, hearing disturbance, and floaters in the right eye. Ophthalmic examination disclosed granulomatous inflammation in the anterior segment, sunset glow fundus and neovascularization at the optic disc. Vogt-Koyanagi-Harada disease was diagnosed and treated with corticosteroid pulse therapy, followed by oral corticosteroids. Three months after the systemic corticosteroid therapy, the neovascularization disappeared.


CONCLUSIONS
Sufficient treatment with systemic corticosteroids is effective for the intraocular neovascularization associated with consecutive inflammation.
Department of Ophthalmology and Visual Science, Graduate School, Tokyo Medical and Dental University, Japan. t.kawaguchi.oph@tmd.ac.jp
Tatsushi
T
Kawaguchi
Mako
M
Yokota
Sunao
S
Sugita
Manabu
M
Mochizuki
D000328:Adult; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage*; D009389:Neovascularization, Pathologic / Q000188:drug therapy*; D009898:Optic Disk; D020551:Pulse Therapy, Drug; D014607:Uveomeningoencephalitic Syndrome / Q000188:drug therapy*
D008775:Methylprednisolone