Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome.
A giant cell tumour is a primary lesion of bone of intermediate severity. Its histogenesis is unclear. In a few cases pulmonary metastases have been described. Multiple skeletal metastases in the absence of sarcomatous change have been observed. We present a case report of a 25-year-old woman with a recurrent giant cell tumour of the distal fibula. After a second recurrence and six years after the initial diagnosis, she rapidly developed multiple bony metastases. The outcome was fatal.
Orthopaedic Department, Tübingen University Hospital, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.
C I
CI
Leichtle
U G
UG
Leichtle
V
V
Gärtner
H
H
Schimmel
J T
JT
Hartmann
M
M
Rudert
D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D005360:Fibula / Q000000981:diagnostic imaging*; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011859:Radiography; D051598:Whole Body Imaging