Planar chiral cyclic amine and its derivatives: synthesis and stereochemical behavior.
Nine-membered diallylic cyclic amines and amides have remarkably stable planar chirality. The transformation of enantiomerically enriched amides provides optically active nitrogen heterocycles containing stereogenic centers in a stereospecific fashion.
Tomooka
Katsuhiko
K
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8552, Japan. ktomooka@apc.titech.ac.jp
Suzuki
Masaki
M
Shimada
Maki
M
Yanagitsuru
Syun-ichi
S
Uehara
Kazuhiro
K