Focal seizures originating from the left temporal lobe in a case with chorea-acanthocytosis.
Neuroacanthocytosis is a group of disorders, clinically characterized with movement disorders, self-mutilation and seizures. There is little information in the literature regarding the clinical and EEG findings of the accompanying seizures in this neurodegenerative disorder. A 46-year-old man who was diagnosed as chorea-acanthocytosis, a subgroup of neuroacanthocytosis, was investigated for severe drug resistant seizures. Continuous video-EEG monitoring revealed an active left temporal epileptogenic focus with left temporal rhythmic discharges detected during his complex partial seizures. T2-weighted cranial MRI indicated hyperintensity of the left amygdala as well as hyperintensity and atrophy of bilateral basal ganglia. We discuss the development of focal seizures in a patient who has a neurodegenerative disease, namely neuroacanthocytosis.
Department of Neurology, Hacettepe University School of Medicine, Ankara, Turkey.
Bedile Irem
BI
Tiftikcioglu
Nese
N
Dericioglu
Serap
S
Saygi
D000328:Adult; D002819:Chorea / Q000175:diagnosis*; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis*; D006801:Humans; D008297:Male; D035583:Rare Diseases / Q000175:diagnosis; D012652:Self Mutilation