Maternal primary hyperparathyroidism: discordant outcomes in a twin pregnancy.
The case reports a neonate (twin 2 of a twin girl pregnancy) presenting with seizures due to hypocalcaemia. The presumptive cause of the hypocalcaemia was maternal hyperparathyroidism with concurrent vitamin D deficiency. The first twin remained free of hypocalcaemia and was vitamin D replete, despite similar exposure in the pregnancy and similar postnatal care.
Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, Victoria, Australia.
Ciara M
CM
McDonnell
Margaret R
MR
Zacharin
D002125:Calcium Gluconate / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000503:physiopathology; D006996:Hypocalcemia / Q000097:blood* / Q000175:diagnosis / Q000628:therapy; D007231:Infant, Newborn; D009035:Mothers; D014427:Twins; D014739:Victoria; D014808:Vitamin D Deficiency / Q000097:blood
D002125:Calcium Gluconate