Fungicidal activity of Artemisia herba alba Asso (Asteraceae).
The antifungal activity of Artemisia herba alba was found to be associated with two major volatile compounds isolated from the fresh leaves of the plant. Carvone and piperitone were isolated and identified by GC/MS, GC/IR, and NMR spectroscopy. Antifungal activity was measured against Penicillium citrinum (ATCC 10499) and Mucora rouxii (ATCC 24905). The antifungal activity (IC50) of the purified compounds was estimated to be 5 microg/ml, 2 microg/ml against Penicillium citrinum and 7 microg/ml, 1.5 microg/ml against Mucora rouxii carvone and piperitone, respectively.
Saleh
Mahmoud A
MA
Department of Chemistry, Texas Southern University, Houston, Texas 77004, USA. saleh_ma@tsu.edu
Belal
Mohamed H
MH
el-Baroty
Gamal
G
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D019306:Artemisia / Q000737:chemistry*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D005658:Fungi / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D009822:Oils, Volatile; D010936:Plant Extracts