[Growth hormone deficiency in children and adults].
Recently, it has become clear that growth hormone (GH) deficiency is by far more frequent disease than it was previously thought. This disorder, associated with remarkable morbidity and mortality, is characterised by a variety of auxological, clinical, genetic, radiological and laboratory abnomalities, which may be pronounced to a different extent in patients. Despite progress made in its recognition and treatment, diagnosis of GH deficiency is still the subject of many debates and controversies. Numerous studies have helped to determine the optimum management of GH replacement in both children and adults. In this paper, aetiology, symptoms, diagnosis and treatment of GH deficiency in various age groups are reviewed with putting special emphasis on the results of recently published studies.
Krysiak
Robert
R
Katedra Farmakologii, Zakład Farmakologii Klinicznej Slaskiej Akademii Medycznej w Katowicach. r.krysiak@pharmanet.com.pl
Okopień
Bogusław
B
Herman
Zbigniew Stanisław
ZS
D000368:Aged; D002648:Child; D003397:Craniopharyngioma / Q000150:complications; D004393:Dwarfism, Pituitary / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D013006:Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications
D013006:Growth Hormone