[Study progress in reversing multidrug resistance to breast cancer with Chinese herbs].
Multidrug resistance of breast cancer is one of the most causes of failure in clinical chemotherapy. It is important to find out some safe and effective drugs to reserve multidrug resistance to breast cancer. The effect of some herbs had been identified in vitro. This article mainly reviewed the research progress in reversing multidrug resistance to breast cancer with Chinese herb. If the herb's effects and safety can be testified in vivo by further research, it will be effectively applied in clinic.
Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China.
Rui-fang
RF
Zhou
Peng-xi
PX
Liu
D018435:ATP Binding Cassette Transporter, Subfamily B / Q000378:metabolism; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004260:DNA Repair / Q000187:drug effects; D004338:Drug Combinations; D018432:Drug Resistance, Multiple; D019008:Drug Resistance, Neoplasm; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D008419:Materia Medica / Q000302:isolation & purification / Q000494:pharmacology; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry
D018435:ATP Binding Cassette Transporter, Subfamily B; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica; D027425:ATP-Binding Cassette, Sub-Family C Proteins