[The role of pro- and antioxidant processes in the liver tissue of guinea pigs in pathogenesis of allergic alveolitis].
It was shown that allergic alveolitis development is accompanied by increase of superoxyddismutase and catalase activity as well as an increase of dien conjugates and malonic dialdehyde content in Guinea pig liver. The administration of alfa-tokoferol acetate, an antioxidant resulted in decrease of these indices in the liver tissue that testifies its correcting influence upon PLO and antioxidant system processes.
Shchepans'kyĭ
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Reheda
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D000542:Alveolitis, Extrinsic Allergic / Q000201:enzymology / Q000209:etiology / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002374:Catalase / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D015227:Lipid Peroxidation / Q000187:drug effects*; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects*; D013482:Superoxide Dismutase / Q000378:metabolism; D024505:Tocopherols; D024502:alpha-Tocopherol / Q000031:analogs & derivatives* / Q000494:pharmacology
D000975:Antioxidants; D008054:Lipid Peroxides; D002374:Catalase; D013482:Superoxide Dismutase; D024502:alpha-Tocopherol; D024505:Tocopherols