Nonlinear modelling approach to human promoter sequences.
By means of the nonlinear modelling technique, we find the nonlinear deterministic structures in the totally 4737 human promoter sequences. These deterministic structures prefer to occur much more outside of a special region around the transcriptional start site. The number and positions of the deterministic structures are basically different for different promoter sequences. Generally, they do not coincide with the CpG islands, the simple repetitive sequences and the low-complexity sequences, which tell us that they should be special structures with biological functions rather than these special segments.
Yang
Huijie
H
Nonlinear Science Center and Department of Modern Physics, University of Science and Technology of China, Hefei Anhui 230026, China. huijieyangn@eyou.com
Zhao
Fangcui
F
Gu
Jianzhong
J
Wang
Binghong
B
D018899:CpG Islands; D015894:Genome, Human; D006801:Humans; D008957:Models, Genetic; D017711:Nonlinear Dynamics; D011401:Promoter Regions, Genetic / Q000235:genetics*