title: Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area.
abstract: Malarial anemia (MA) is a multifactorial disease for which the complex etiological basis is only partially defined. The association of clinical, nutritional, demographic, and socioeconomic factors with parasitemia, anemia, and MA was determined for children presenting at a hospital in a holoendemic area of Plasmodium falciparum transmission in western Kenya. Parasitemia was not associated with malaria disease severity. In univariate logistic regression, fever was significantly associated with parasitemia, and wasting was associated with increased presentation of MA. Caretaker's level of education and occupation were significantly correlated with parasitemia, anemia, and MA. Housing structure was also significantly associated with parasitemia and anemia. Bed net use was protective against parasitemia but not anemia or MA. Multivariate logistic regression models demonstrated that fever, mother's occupation, and bed net use were associated with parasitemia. In the current study, none of the factors were associated with anemia or MA in the multivariate models.
authors.affiliation: University of Pittsburgh/KEMRI Laboratories of Parasitic and Viral Diseases, Kenya Medical Research Institute, Center for Vector Biology and Control Research, Kisumu, Kenya.
authors.forename: John Michael
authors.initials: JM
authors.lastname: Ong'echa
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Keller
authors.forename: Tom
authors.initials: T
authors.lastname: Were
authors.forename: Collins
authors.initials: C
authors.lastname: Ouma
authors.forename: Richard O
authors.initials: RO
authors.lastname: Otieno
authors.forename: Zachary
authors.initials: Z
authors.lastname: Landis-Lewis
authors.forename: Daniel
authors.initials: D
authors.lastname: Ochiel
authors.forename: Jamie L
authors.initials: JL
authors.lastname: Slingluff
authors.forename: Stephen
authors.initials: S
authors.lastname: Mogere
authors.forename: George A
authors.initials: GA
authors.lastname: Ogonji
authors.forename: Alloys S
authors.initials: AS
authors.lastname: Orago
authors.forename: John M
authors.initials: JM
authors.lastname: Vulule
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Kaplan
authors.forename: Richard D
authors.initials: RD
authors.lastname: Day
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Perkins
mesh_terms: D000740:Anemia / Q000097:blood / Q000453:epidemiology / Q000469:parasitology*; D000818:Animals; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D019353:Endemic Diseases; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006798:Housing; D006801:Humans; D007223:Infant; D007630:Kenya / Q000453:epidemiology; D016778:Malaria, Falciparum / Q000097:blood / Q000150:complications* / Q000453:epidemiology / Q000469:parasitology; D008297:Male; D009752:Nutritional Status; D018512:Parasitemia / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000254:growth & development*; D012424:Rural Population; D012923:Social Class
chemical_list: D006454:Hemoglobins