title: [Present possibilities of Q fever therapy.].
abstract: The first-line therapy for acute Q fever is 14 to 21 days of doxycycline, or fluoroquinolones such as ofloxacin or pefloxacin. Clarithromycin is a potential effective alternative. Chronic Q fever, especially endocarditis, requires treatment for at least 18 months, with the preferred combination of doxycycline and hydroxychloroquine. An alternative treatment for chronic Q fever, when adverse effects of hydroxychloroquine are a problem, is the combination of doxycycline and fluoroquinolones with extended therapy for 3 years or more. Serologic tests may be used to monitor the response to therapy.
authors.affiliation: Department of Epidemiology, Medical Faculty of P.J.Safárik University Kosice, Slovak republic.
authors.forename: Erik
authors.initials: E
authors.lastname: Dorko
authors.forename: Lýdia
authors.initials: L
authors.lastname: Cisláková
authors.forename: Peter
authors.initials: P
authors.lastname: Kizek
mesh_terms: D016997:Coxiella burnetii; D004318:Doxycycline; D006801:Humans; D006979:Hyperthermia, Induced; D015242:Ofloxacin; D011778:Q Fever
chemical_list: D015242:Ofloxacin; D004318:Doxycycline