title: Langerhans' cell histiocytosis: a case report of an eosinophilic granuloma of the mandible treated with bone graft surgery and endosseous titanium implants.
abstract: Eosinophilic granuloma is the localized and most benign form of Langerhans' cell histiocytosis. The disease shows a particular predilection for the head and neck region and usually involves the skull bones, where it manifests as well-defined lytic lesions on standard radiographs. The case of an extensive lesion involving the body of the mandible in a 52-year-old man is reported. Operative procedures consisted of enucleation of the lytic lesion and follow-up with clinical examinations and computerized tomographic studies of the mandible at 2, 12, and 18 months postoperatively. Reconstructive surgery without radiotherapy was performed with an autologous bone graft from the iliac crest and implant placement to provide support for a dental restoration.
authors.affiliation: Department of Surgery, University of Pisa, Italy. lsbordon@med.unipi.it
authors.forename: Ludovico
authors.initials: L
authors.lastname: Sbordone
authors.forename: Franco
authors.initials: F
authors.lastname: Guidetti
authors.forename: Giovanni Battista
authors.initials: GB
authors.lastname: Menchini Fabris
authors.forename: Carolina
authors.initials: C
authors.lastname: Sbordone
mesh_terms: D016025:Bone Transplantation / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000534:rehabilitation* / Q000601:surgery; D006801:Humans; D007085:Ilium / Q000637:transplantation; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000534:rehabilitation* / Q000601:surgery; D008875:Middle Aged; D011859:Radiography
chemical_list: D015921:Dental Implants