[Detection of blood opiates by fluorescence-polarization immunoassay].
It was found possible to use fluorescence-polarization immunoassay (FPIA) in screening of opium drugs in blood and blood serum as a preliminary test. The results of the study of blood and serum samples by FPIA and chromato-mass-spectroscopy were compared. As a criterion of assessment of the preliminary study results we propose to use a cutoff point by serial production of the analysed blood samples of the threshold morphine concentrations (20 ng/ml for living subjects and 40 ng/ml--for corpses). The method of opiates screening in blood proposed is characterized by fast conduction, high specificity and precision, small amounts of the expert material.
Kataev
S S
SS
Zelenina
N B
NB
Oborin
D B
DB
Malkova
T L
TL
D002102:Cadaver; D016231:Fluorescence Polarization Immunoassay; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D009020:Morphine / Q000097:blood*; D012680:Sensitivity and Specificity
D009020:Morphine