title: Spontaneous lymphoma in a prairie dog (Cynomys ludovicianus).
abstract: A 4-year-old, female, black-tailed prairie dog (Cynomys ludovicianus) was examined for acute dyspnea and two skin masses. Tentative diagnosis of lymphoma was made based on cytology of pleural effusion and the skin masses. Administration of prednisolone was initially effective in improving the condition; however, the clinical signs deteriorated after radiation therapy and administration of cyclophosphamide. Postmortem examination revealed that neoplastic lymphocytes had infiltrated most of the organs, and the histopathological diagnosis was multi-centric lymphoma.
authors.affiliation: Departments of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo.
authors.forename: Yasutsugu
authors.initials: Y
authors.lastname: Miwa
authors.forename: Satoru
authors.initials: S
authors.lastname: Matsunaga
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayama
authors.forename: Asuka
authors.initials: A
authors.lastname: Kurosawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ogawa
authors.forename: Nobuo
authors.initials: N
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D011239:Prednisolone / Q000627:therapeutic use; D018714:Radiotherapy, Adjuvant / Q000662:veterinary*; D012376:Rodent Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012589:Sciuridae
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide; D011239:Prednisolone