title: Linezolid in the treatment of brain abscess due to Peptostreptococcus.
abstract: Brain abscesses can be caused by bacteria, fungi, and parasites. Among bacteria, anaerobic organisms include the Bacteroides species group, Fusobacterium, Peptostreptococcus, and Propionibacterium. In these cases, a 4-week course of parenteral penicillin/cefalosporin and metronidazole is the standard of treatment. We describe a case of brain abscess secondary to anaerobic infection with Peptostreptococcus, which was successfully treated with parenteral and oral linezolid after failure of standard therapy.
authors.affiliation: Department of Infectious and Tropical Diseases, University Hospital, Padova, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Salin
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Vianello
authors.forename: Renzo
authors.initials: R
authors.lastname: Manara
authors.forename: Erika
authors.initials: E
authors.lastname: Morelli
authors.forename: Annamaria
authors.initials: A
authors.lastname: Cattelan
authors.forename: Marino
authors.initials: M
authors.lastname: Scarin
authors.forename: Dino
authors.initials: D
authors.lastname: Sgarabotto
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001922:Brain Abscess / Q000188:drug therapy* / Q000382:microbiology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D000069349:Linezolid; D008297:Male; D023303:Oxazolidinones / Q000627:therapeutic use*; D010462:Peptostreptococcus / Q000187:drug effects*; D013788:Thalamus / Q000382:microbiology*; D016896:Treatment Outcome
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid