title: Sildenafil as treatment for Human Immunodeficiency Virus-related pulmonary hypertension in a child.
abstract: Human Immunodeficiency Virus (HIV)-related pulmonary hypertension is a relatively rare disease that can affect HIV sufferers. This is almost always associated with a poor outcome and death. An 18 month-old girl, probably the youngest on record, was diagnosed to have pulmonary hypertension (PHT) and retrospectively found to have HIV infection. Sildenafil was used to control her PHT and she remains alive even after 2 years.
authors.affiliation: Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan. rahim@kck.usm.my
authors.forename: Abdul Rahim
authors.initials: AR
authors.lastname: Wong
authors.forename: Aida Hanum G
authors.initials: AH
authors.lastname: Rasool
authors.forename: Nik Zainal
authors.initials: NZ
authors.lastname: Abidin
authors.forename: Abdul Rahmand
authors.initials: AR
authors.lastname: Noor
authors.forename: Ban Seng
authors.initials: BS
authors.lastname: Quah
mesh_terms: D006332:Cardiomegaly / Q000150:complications; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D007223:Infant; D010879:Piperazines / Q000008:administration & dosage* / Q000627:therapeutic use; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate