Resection of colorectal liver metastases: current perspectives.
BACKGROUND
Metastases to the liver is the leading cause of death in patients with colorectal cancer.


METHODS
The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered.


RESULTS
Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%.


CONCLUSIONS
By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.
McLoughlin
James M
JM
Gastrointestinal Tumor Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612-9497, USA.
Jensen
Eric H
EH
Malafa
Mokenge
M
D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D020360:Neoadjuvant Therapy; D018579:Patient Selection; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome