title: Childhood IQ in relation to obesity and weight gain in adult life: the National Child Development (1958) Study.
abstract: OBJECTIVE
  To examine the relation of childhood intelligence (IQ) test results with obesity in middle age and weight gain across the life course.
  
  
  METHODS
  We analysed data from the National Child Development (1958) Study, a prospective cohort study of 17 414 births to parents residing in Great Britain in the late 1950s. Childhood IQ was measured at age 11 years and body mass index (BMI), an indicator of adiposity, was assessed at 16, 23, 33 and 42 years of age. Logistic regression (in which BMI was categorised into obese and non-obese) and structural equation growth curve models (in which BMI was retained as a continuous variable) were used to estimate the relation between childhood IQ and adult obesity, and childhood IQ and weight gain, respectively.
  
  
  RESULTS
  In unadjusted analyses, lower childhood IQ scores were associated with an increased prevalence of adult obesity at age 42 years. This relation was somewhat stronger in women (OR(per SD decrease in IQ score) [95% CI]: 1.38 [1.26, 1.50]) than men (1.26 [1.15, 1.38]). This association remains statistically significant after adjusting for childhood characteristics, including socio-economic factors, but was heavily attenuated following control for adult characteristics, particularly education (women: 1.11 [0.99, 1.25]; men: 1.10 [0.98, 1.23]). When weight gain between age 16 and 42 years was the outcome of interest, structural equation modelling revealed that education and dietary characteristics in adult life mediated the association with childhood IQ.
  
  
  CONCLUSIONS
  A lower IQ score in childhood is associated with obesity and weight gain in adulthood. In the present study, this relation appears to be largely mediated via educational attainment and the adoption of healthy diets in later life.
authors.affiliation: Department of Epidemiology and Public Health, University College London, London, UK.
authors.forename: T
authors.initials: T
authors.lastname: Chandola
authors.forename: I J
authors.initials: IJ
authors.lastname: Deary
authors.forename: D
authors.initials: D
authors.lastname: Blane
authors.forename: G D
authors.initials: GD
authors.lastname: Batty
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D015331:Cohort Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D007360:Intelligence; D007361:Intelligence Tests; D008297:Male; D009765:Obesity / Q000523:psychology*; D011446:Prospective Studies; D012959:Socioeconomic Factors; D015430:Weight Gain / Q000502:physiology*