Genetic host resistance and susceptibility to leprosy.
Leprosy is a chronic infectious disease that affects 600,000 new individuals worldwide every year. This article summarizes some of the advances achieved over the past decades towards the description of the exact number, location and nature of the genetic variants responsible for the well established genetic component controlling leprosy susceptibility in humans.
Mira
Marcelo Távora
MT
Pontifical Catholic University of Paraná, Graduate Program in Health Sciences, Rua Imaculada Conceição, 1155, CCBS, PPGCS, CEP 80215-901, Curitiba, Paraná, Brazil. m.mira@pucpr.br
D020022:Genetic Predisposition to Disease; D015894:Genome, Human; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007918:Leprosy / Q000235:genetics* / Q000276:immunology; D011110:Polymorphism, Genetic
D006680:HLA Antigens