Nano nickel oxide/nickel incorporated nickel composite coating for sensing and estimation of acetylcholine.
Pure nickel electrodes can be used as biosensors especially for sensing and estimating acetylcholine neurotransmitter. In the present work, a good electrochemical sensor was developed by electroplating nano nickel oxide reinforced nickel on graphite substrate. The morphology of the working electrode surface was studied by using a scanning electron microscope (SEM). The electrochemical and biological performance of the modified electrode was characterized by polarization studies in different media. The present modified electrode showed good sensing performance with a response time as low as 8s during sensing and estimation of acetylcholine. The sensitivity of the modified electrode was 34.88 microA/(microM cm(2)).
Shibli
S M A
SM
Department of Chemistry, University of Kerala, Kariavottom Campus, Trivandrum, Kerala 695581, India. smashibli@yahoo.com
Beenakumari
K S
KS
Suma
N D
ND
D000109:Acetylcholine / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D004563:Electrochemistry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008839:Microelectrodes; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D009532:Nickel / Q000737:chemistry*; D010316:Particle Size
D020099:Coated Materials, Biocompatible; D009532:Nickel; C028007:nickel monoxide; D000109:Acetylcholine