[Microbiological study of persistent rhinosinusitis after endoscopic sinus surgery].
OBJECTIVE
To investigate the microbiology of persistent rhinosinusitis after endoscopic sinus surgery (ESS).


METHODS
A total of 143 patients with chronic rhinosinusitis (CRS) were selected to performed the endoscopy sinus surgery, cultures of the purulent discharges from ethmoid sinus were obtained during the operation. The patients were then followed for more than 6 months. Cultures were obtained in 49 patients who were not successfully cured 6 months after surgery. Culture results were compared between two groups.


RESULTS
Of 143 specimens taken during the operation, 153 isolates were detected. Of 49 specimens taken from ethmoids postoperatively, 65 isolates were detected. Between two groups, there was no significant difference in the detection rate of Gram-positive coccus, and there was significant difference in the detection rate of Gram-negative rod and anaerobic bacteria. The detection rate of antibiotic-resistant organisms were significantly higher in postoperative specimens than in preoperative specimens.


CONCLUSIONS
Bacteria infection is one of the etiological factors of persistent rhinosinusitis after ESS. Of the pathogenic bacteria of postoperative rhinosinusitis, Gram-positive coccus are continued to be predominant. Gram-negative rods are comparatively increased. While anaerobes are reduced. Antibiotic resistant organisms are more frequent. To treat the postoperative rhinosinusitis, obtaining a culture of the postoperative sinus cavity may therefore be important.
Li
Yanni
Y
Department of Otolaryngology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Liu
Banghua
B
Kong
Weijia
W
D000328:Adult; D000368:Aged; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001424:Bacterial Infections / Q000382:microbiology*; D002908:Chronic Disease; D024881:Drug Resistance, Bacterial; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures / Q000009:adverse effects; D010256:Paranasal Sinuses / Q000601:surgery; D011184:Postoperative Period; D012852:Sinusitis / Q000382:microbiology*