Leydig cell tumor after treatment for Ewing's sarcoma.
Leydig cell tumors account for 3% of testicular tumors and have never been reported after treatment for Ewing's sarcoma. We report the unusual occurrence of a patient who developed a Leydig cell tumor of the testis 18 years after successful treatment for Ewing's sarcoma. Additional monitoring for second malignancies may become appropriate as long-term survival continues to improve for patients with Ewing's sarcoma.
Butros
Linda J
LJ
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Phillip
Shaji
S
Chou
Alexander
A
Meyers
Paul A
PA
Huvos
Andrew G
AG
Healey
John H
JH
Russo
Paul
P
Gorlick
Richard G
RG
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007984:Leydig Cell Tumor / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000601:surgery; D012512:Sarcoma, Ewing / Q000175:diagnosis* / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013995:Time; D016896:Treatment Outcome