title: [Nervous system involvement in hemorrhagic fever with renal syndrome].
abstract: The authors of the article describe two cases of hemorrhagic fever with renal syndrome (HFRS) with prevalence of signs of nervous system involvement. The first case was a 40-year-old woman with moderate HFRS, who developed Guillain-Barre syndrome of axonal-demyelinating polyneuropathy. An important observation was the absence of hemorrhagic or renal syndrome; combined therapy including plasmapheresis was successful. The second case demonstrated polymorphism of HFRS clinical manifestations with prevalence of neurological symptoms, which consisted in encephalopathy and no renal failure signs; hemorrhagic syndrome was moderate. In both cases the diagnosis was confirmed by elevated titer of antibodies to HFRS virus, belonging to the group of hantaviruses.
authors.forename: N D
authors.initials: ND
authors.lastname: Iushchuk
authors.forename: E P
authors.initials: EP
authors.lastname: Dekonenko
authors.forename: G N
authors.initials: GN
authors.lastname: Karetkina
authors.forename: G M
authors.initials: GM
authors.lastname: Kulagina
authors.forename: S A
authors.initials: SA
authors.lastname: Makarova
authors.forename: F V
authors.initials: FV
authors.lastname: Rumo
authors.forename: Z E
authors.initials: ZE
authors.lastname: Bakulina
authors.forename: T K
authors.initials: TK
authors.lastname: Dzagurova
authors.forename: A I
authors.initials: AI
authors.lastname: Berko
authors.forename: S V
authors.initials: SV
authors.lastname: Shakhgil'dian
authors.forename: E A
authors.initials: EA
authors.lastname: Tkachenko
mesh_terms: D000293:Adolescent; D000328:Adult; D018792:Encephalitis, Viral / Q000503:physiopathology / Q000821:virology*; D005260:Female; D020275:Guillain-Barre Syndrome / Q000503:physiopathology / Q000821:virology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications* / Q000503:physiopathology; D006801:Humans