title: Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
abstract: The structure of a conserved hypothetical protein, PlasmoDB sequence MAL13P1.257 from Plasmodium falciparum, Pfam sequence family PF05907, has been determined as part of the structural genomics effort of the Structural Genomics of Pathogenic Protozoa consortium. The structure was determined by multiple-wavelength anomalous dispersion at 2.17 A resolution. The structure is almost entirely beta-sheet; it consists of 15 beta-strands and one short 3(10)-helix and represents a new protein fold. The packing of the two monomers in the asymmetric unit indicates that the biological unit may be a dimer.
authors.affiliation: Structural Genomics of Pathogenic Protozoa Consortium, USA.
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Holmes
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Buckner
authors.forename: Wesley C
authors.initials: WC
authors.lastname: Van Voorhis
authors.forename: Christopher
authors.initials: C
authors.lastname: Mehlin
authors.forename: Erica
authors.initials: E
authors.lastname: Boni
authors.forename: Thomas N
authors.initials: TN
authors.lastname: Earnest
authors.forename: George
authors.initials: G
authors.lastname: DeTitta
authors.forename: Joseph
authors.initials: J
authors.lastname: Luft
authors.forename: Angela
authors.initials: A
authors.lastname: Lauricella
authors.forename: Lori
authors.initials: L
authors.lastname: Anderson
authors.forename: Oleksandr
authors.initials: O
authors.lastname: Kalyuzhniy
authors.forename: Frank
authors.initials: F
authors.lastname: Zucker
authors.forename: Lori W
authors.initials: LW
authors.lastname: Schoenfeld
authors.forename: Wim G J
authors.initials: WG
authors.lastname: Hol
authors.forename: Ethan A
authors.initials: EA
authors.lastname: Merritt
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018360:Crystallography, X-Ray; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000737:chemistry*; D020836:Protein Structure, Quaternary; D017433:Protein Structure, Secondary; D015800:Protozoan Proteins / Q000737:chemistry*; D016415:Sequence Alignment
chemical_list: D015800:Protozoan Proteins