title: GARBAN II: an integrative framework for extracting biological information from proteomic and genomic data.
abstract: Genomic and proteomic analyses generate a massive amount of data that requires specific bioinformatic tools for its management and interpretation. GARBAN II, developed from the previous GARBAN platform, provides an integrated framework to simultaneously analyse and compare multiple datasets from DNA microarrays and proteomic studies. The general architecture, gene classification and comparison, and graphical representation have been redesigned to ensure a user-friendly feature and to improve the capabilities and efficiency of this system. Additionally, GARBAN II has been extended with new applications to display networks of coexpressed genes and to integrate access to BioRag and MotifScanner so as to facilitate the holistic analysis of users' data.
authors.affiliation: Centro de Estudios e Investigaciones Técnicas de Guipúzcoa (CEIT) and Escuela Superior de Ingenieros de la Universidad de Navarra (TECNUN), San Sebastián, Spain.
authors.forename: Victoriano
authors.initials: V
authors.lastname: Segura
authors.forename: Adam
authors.initials: A
authors.lastname: Podhorski
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Guruceaga
authors.forename: José L
authors.initials: JL
authors.lastname: Sevilla
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Corrales
authors.forename: Angel
authors.initials: A
authors.lastname: Rubio
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D003628:Database Management Systems / Q000639:trends*; D020869:Gene Expression Profiling; D016678:Genome; D023281:Genomics; D006801:Humans; D040901:Proteomics