title: Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase.
abstract: Characterisation of recombinant Streptomyces spheroides NovW in vitro suggests that it is not a kinetically competent dual action dTDP-6-deoxy-d-xylo-4-hexulose 3,5-epimerase, but possesses only significant 3-epimerase activity.
authors.affiliation: Centre for Carbohydrate Chemistry, University of East Anglia, Norwich, NR4 7TJ, UK.
authors.forename: Mónica
authors.initials: M
authors.lastname: Tello
authors.forename: Piotr
authors.initials: P
authors.lastname: Jakimowicz
authors.forename: James C
authors.initials: JC
authors.lastname: Errey
authors.forename: Caren L
authors.initials: CL
authors.lastname: Freel Meyers
authors.forename: Christopher T
authors.initials: CT
authors.lastname: Walsh
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Buttner
authors.forename: David M
authors.initials: DM
authors.lastname: Lawson
authors.forename: Robert A
authors.initials: RA
authors.lastname: Field
mesh_terms: D002238:Carbohydrate Epimerases / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D007700:Kinetics; D008958:Models, Molecular; D015394:Molecular Structure; D009675:Novobiocin / Q000096:biosynthesis / Q000737:chemistry; D012997:Solvents; D013302:Streptomyces / Q000737:chemistry* / Q000201:enzymology*
chemical_list: D012997:Solvents; D009675:Novobiocin; D002238:Carbohydrate Epimerases