[Antibacterial effect of Jinzhi Hanshuye on infected root canals].
OBJECTIVE
To evaluate antibacterial effects of Jinzhi Hanshuye on infected root canals.


METHODS
30 infected single-root-canals were collected from 27 clinical patients, and randomly divided into two groups. In the experimental group, Jinzhi Hanshuye was used as irrigating solution and intracanal medicament, while in the control group tosylchloramide sodium irrigating and calcium hydroxide disinfecting root canals were adopted. Microbiological sampling was performed before treatment, after instrumentation, and after intracanal medication. The frequency of positive culture and CFU of each culture were evaluated by ANOVA.


RESULTS
The frequency of positive culture was dropped from 73.3% to 46.7% after instrumentation and to 13.3% after medication in the experimental group, while in the control group the frequency was dropped from 73.3% to 20.0% and 26.7% after medication (P=0.9721). CFU was dropped from 1462.9 to 27.9 after instrumentation and 15.7 after medication, while in the control group CFU was dropped from 1402.8 to 14.0 and 45.1 after medication (P=0.688).


CONCLUSIONS
Jinzhi Hanshuye had good antibacterial effects on anaerobics of infected root canals.
Liu
Chang-hong
CH
Guangdong Provincial Stomatological Hospital, Nanfang Medical University, Guangzhou 510280, Guangdong Province, China.
Yin
Shi-hai
SH
Chen
Lei
L
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002126:Calcium Hydroxide; D003786:Dental Pulp Cavity / Q000187:drug effects*; D006801:Humans; D012388:Root Canal Irrigants / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D012388:Root Canal Irrigants; D002126:Calcium Hydroxide