Microscopic polyangitis triggered by fungal infection.
We report a case of microscopic polyangitis associated with fungal infection. A 64-year-old man was admitted to our hospital because of renal dysfunction and high fever. He complained of arthralgia and myalgia. He was diagnosed with antineutrophil cytoplasmic antibody-related vasculitis and also had a fungal infection. We treated him with antibiotics including fluconazole. All symptoms disappeared as the infection resolved without the use of steroid therapy. We speculate that the deteriorating vasculitis could have been triggered by overproduction of cytokines in response to the fungal infection.
Kon
Yujiro
Y
Division of Clinical Immunology and Hematology, Department of Medicine, Sapporo City General Hospital, Sapporo 060-8604, Japan.
Bohgaki
Miyuki
M
Notoya
Atsushi
A
Mukai
Masaya
M
Kohno
Michifumi
M
Sato
Hidetoshi
H
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000150:complications* / Q000188:drug therapy; D015725:Fluconazole / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014657:Vasculitis / Q000209:etiology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D000935:Antifungal Agents; D015725:Fluconazole