title: Polyarthritis and familial pulmonary fibrosis in a child.
abstract: A 7-year-old girl presented with seropositive polyarthritis, autoimmune thyroiditis, and pulmonary fibrosis. Several family members had complex autoimmune disorders and pulmonary fibrosis, and the pedigree was consistent with autosomal dominant inheritance. The possible links between polyarthritis and familial pulmonary fibrosis are discussed, as well as the therapeutic challenges raised by this extraordinarily rare combination.
authors.affiliation: Pediatric Orthopedic Surgery Department, la Timone Teaching Hospital, boulevard Jean Moulin, 13005 Marseille, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Launay
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Guillaume
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Gennari
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Gonzales
authors.forename: Gérard
authors.initials: G
authors.lastname: Bollini
authors.forename: Isabelle
authors.initials: I
authors.lastname: Koné Paut
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications* / Q000235:genetics / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D010375:Pedigree; D011658:Pulmonary Fibrosis / Q000150:complications* / Q000235:genetics / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000235:genetics / Q000276:immunology; D014222:Triamcinolone Acetonide / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D014222:Triamcinolone Acetonide; C005900:triamcinolone hexacetonide