[Present possibilities of Q fever therapy.].
The first-line therapy for acute Q fever is 14 to 21 days of doxycycline, or fluoroquinolones such as ofloxacin or pefloxacin. Clarithromycin is a potential effective alternative. Chronic Q fever, especially endocarditis, requires treatment for at least 18 months, with the preferred combination of doxycycline and hydroxychloroquine. An alternative treatment for chronic Q fever, when adverse effects of hydroxychloroquine are a problem, is the combination of doxycycline and fluoroquinolones with extended therapy for 3 years or more. Serologic tests may be used to monitor the response to therapy.
Dorko
Erik
E
Department of Epidemiology, Medical Faculty of P.J.Safárik University Kosice, Slovak republic.
Cisláková
Lýdia
L
Kizek
Peter
P
D016997:Coxiella burnetii; D004318:Doxycycline; D006801:Humans; D006979:Hyperthermia, Induced; D015242:Ofloxacin; D011778:Q Fever
D015242:Ofloxacin; D004318:Doxycycline