title: Biological and biomechanical evaluation of interface reaction at conical screw-type implants.
abstract: BACKGROUND
  Initial stability of the implant is, in effect, one of the fundamental criteria for obtaining long-term osseointegration. Achieving implant stability depends on the implant-bone relation, the surgical technique and on the microscopic and macroscopic morphology of the implant used. A newly designed parabolic screw-type dental implant system was tested in vivo for early stages of interface reaction at the implant surface.
  
  
  METHODS
  A total of 40 implants were placed into the cranial and caudal part of the tibia in eight male Göttinger minipigs. Resonance frequency measurements (RFM) were made on each implant at the time of fixture placement, 7 days and 28 days thereafter in all animals. Block biopsies were harvested 7 and 28 days (four animals each) following surgery. Biomechanical testing, removable torque tests (RTV), resonance frequency analysis; histological and histomorphometric analysis as well as ultrastructural investigations (scanning electron microscopy (SEM)) were performed.
  
  
  RESULTS
  Implant stability in respect to the measured RTV and RFM-levels were found to be high after 7 days of implants osseointegration and remained at this level during the experimented course. Additionally, RFM level demonstrated no alteration towards baseline levels during the osseointegration. No significant increase or decrease in the mean RFM (6029 Hz; 6256 Hz and 5885 Hz after 0-, 7- and 28 days) were observed. The removal torque values show after 7 and 28 days no significant difference. SEM analysis demonstrated a direct bone to implant contact over the whole implant surface. The bone-to-implant contact ratio increased from 35.8 +/- 7.2% to 46.3 +/- 17.7% over time (p = 0,146).
  
  
  CONCLUSIONS
  The results of this study indicate primary stability of implants which osseointegrated with an intimate bone contact over the whole length of the implant.
authors.affiliation: Department of Cranio-Maxillofacial Surgery, University of Münster, Münster, Germany. buchtea@uni-muenster.de
authors.forename: Andre
authors.initials: A
authors.lastname: Büchter
authors.forename: Ulrich
authors.initials: U
authors.lastname: Joos
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Wiesmann
authors.forename: László
authors.initials: L
authors.lastname: Seper
authors.forename: Ulrich
authors.initials: U
authors.lastname: Meyer