title: Recognizing primary immune deficiency in clinical practice.
abstract: Primary immunodeficiency results in recurrent infections, organ dysfunction, and autoimmunity. We studied 237 patients referred for suspicion of immunodeficiency, using a scoring system based on clinical information. The 113 patients with immunodeficiency had higher scores and more episodes of chronic illnesses and were more likely to have neutropenia, lymphopenia, or splenomegaly.
authors.affiliation: Department of Medicine, Mount Sinai Medical Center, 1425 Madison Ave., New York, NY 10029, USA. hale.yar@mssm.edu
authors.forename: Hale
authors.initials: H
authors.lastname: Yarmohammadi
authors.forename: Lissette
authors.initials: L
authors.lastname: Estrella
authors.forename: John
authors.initials: J
authors.lastname: Doucette
authors.forename: Charlotte
authors.initials: C
authors.lastname: Cunningham-Rundles
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis*; D007223:Infant; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index