[Adherence of Candida albicans is inhibited by yeast mannan].
The adherence of Candida albicans strain NIH A207 to plastic plates was inhibited by the addition of mannan, and plates coated with mannan also inhibited the adherence of C. albicans strains TIMM1768, TIMM2640, and JCM2076. Mannan coated the plastic plates under neutral and acidic conditions, but not under alkaline conditions. These results indicate that C. albicans cannot attach to mannan. Thus mannan-coated medical equipment might be useful to prevent C. albicans adherence.
Iwamoto
Luna
L
Department of Microbiology, Tohoku Pharmaceutical University, Sendai City, Japan.
Watanabe
Toshihiko
T
Ogasawara
Ayako
A
Mikami
Takeshi
T
Matsumoto
Tatsuji
T
D002176:Candida albicans / Q000502:physiology*; D002448:Cell Adhesion / Q000187:drug effects*; D003864:Depression, Chemical; D004389:Durable Medical Equipment / Q000382:microbiology; D006863:Hydrogen-Ion Concentration; D008351:Mannans / Q000494:pharmacology*; D010969:Plastics; D012441:Saccharomyces cerevisiae / Q000737:chemistry
D008351:Mannans; D010969:Plastics