title: [Clinical and MRI findings of patients with internuclear ophthalmoplegia].
abstract: Internuclear ophthalmoplegia (INO) is a distinctive ocular motor disorder resulting from dysfunction of the medial longitudinal fasciculus, which lies in the pontine tegmentum. We retrospectively analyzed clinical and magnetic resonance imaging (MRI) findings for four consecutive patients with internuclear ophthalmoplegia who were treated in our hospital. The causes of the disease were cerebral infarction in three cases and multiple sclerosis in one case. Vertigo and facial nerve palsy were associated in three cases and one case, respectively. MRI studies visualized an ischemic lesion in the responsible portion of the brainstem in one patient but failed to reveal responsible lesions in the other three patients. All the patients completely recovered in 1 to 22 days, with an average recovery period of 9.3 days. The etiology, diagnosis and management of INO were bibliographically reviewed.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka.
authors.forename: Toyoaki
authors.initials: T
authors.lastname: Ohbuchi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Udaka
authors.forename: Naokimi
authors.initials: N
authors.lastname: Tokui
authors.forename: Hidenaga
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Teruo
authors.initials: T
authors.lastname: Shiomori
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Fujimura
authors.forename: Takashi
authors.initials: T
authors.lastname: Shimizu
authors.forename: Hideaki
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015835:Ocular Motility Disorders / Q000175:diagnosis; D012189:Retrospective Studies