title: Beta 3 integrin expression on T cells from renal allograft recipients.
abstract: Recent studies emphasize the paramount significance of beta 3 integrin in cell adhesion and homing, which may be particularly relevant in cancer progression and metastasis. In contrast, the presence and potential role of beta 3 on human T cells is practically unknown. We show that T cells can express significant amounts of alpha-beta 3 integrin (CD41/CD61), and the expression of alpha(v)-beta 3 (CD51/CD61) remains very low. T-cell beta 3 integrin is probably transferred by platelet-derived microparticles.
authors.affiliation: Transplantation Institute, Warsaw Medical University, ul. Nowogrodzka 59, 02-006 Warsaw, Poland. wieslawa_lojek@poczta.onet.pl
authors.forename: P
authors.initials: P
authors.lastname: Wierzbicki
authors.forename: D
authors.initials: D
authors.lastname: Kłosowska
authors.forename: J
authors.initials: J
authors.lastname: Wyzgał
authors.forename: M
authors.initials: M
authors.lastname: Nowaczyk
authors.forename: A
authors.initials: A
authors.lastname: Przerwa
authors.forename: M
authors.initials: M
authors.lastname: Kniotek
authors.forename: A
authors.initials: A
authors.lastname: Górski
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D006801:Humans; D039661:Integrin beta3 / Q000235:genetics*; D016030:Kidney Transplantation / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014184:Transplantation, Homologous
chemical_list: D015703:Antigens, CD; D039661:Integrin beta3