title: Leydig cell tumor after treatment for Ewing's sarcoma.
abstract: Leydig cell tumors account for 3% of testicular tumors and have never been reported after treatment for Ewing's sarcoma. We report the unusual occurrence of a patient who developed a Leydig cell tumor of the testis 18 years after successful treatment for Ewing's sarcoma. Additional monitoring for second malignancies may become appropriate as long-term survival continues to improve for patients with Ewing's sarcoma.
authors.affiliation: Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Butros
authors.forename: Shaji
authors.initials: S
authors.lastname: Phillip
authors.forename: Alexander
authors.initials: A
authors.lastname: Chou
authors.forename: Paul A
authors.initials: PA
authors.lastname: Meyers
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Huvos
authors.forename: John H
authors.initials: JH
authors.lastname: Healey
authors.forename: Paul
authors.initials: P
authors.lastname: Russo
authors.forename: Richard G
authors.initials: RG
authors.lastname: Gorlick
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007984:Leydig Cell Tumor / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000601:surgery; D012512:Sarcoma, Ewing / Q000175:diagnosis* / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013995:Time; D016896:Treatment Outcome