title: Usefulness of eschar PCR for diagnosis of scrub typhus.
abstract: We report here on the case of a child who was infected with scrub typhus, and we made the diagnosis according to the serology and by performing PCRs on the child's eschar. The patient was treated with azithromycin, and he did not experience any complications. Performing nested PCR on the eschar might be both a rapid diagnostic test for scrub typhus in the early acute stage and a differential test as to whether or not a scab is a scrub typhus eschar.
authors.affiliation: Department of Pediatrics, Seonam University College of Medicine, Gwangju, South Korea.
authors.forename: Seung-Hyun
authors.initials: SH
authors.lastname: Lee
authors.forename: Dong-Min
authors.initials: DM
authors.lastname: Kim
authors.forename: Young Shin
authors.initials: YS
authors.lastname: Cho
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Yoon
authors.forename: Soo Kyoung
authors.initials: SK
authors.lastname: Shim
mesh_terms: D000942:Antigens, Bacterial / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D002648:Child; D017931:DNA Primers / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics; D012285:Orientia tsutsugamushi / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction / Q000379:methods*; D012612:Scrub Typhus / Q000175:diagnosis* / Q000382:microbiology; D012867:Skin / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D017931:DNA Primers; D004269:DNA, Bacterial; D008565:Membrane Proteins; C064828:Sta56 antigen, Rickettsia tsutsugamushi