title: Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates.
abstract: The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.
authors.affiliation: Department of Material and Life Science, Graduate School of Engineering, Osaka University, SORST, Japan Science and Technology Agency, JST, Suita, Osaka 565-0871, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Ohkubo
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Moro-oka
authors.forename: Shunichi
authors.initials: S
authors.lastname: Fukuzumi
mesh_terms: D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006859:Hydrogen; D006860:Hydrogen Bonding; D007700:Kinetics; D008958:Models, Molecular; D018377:Neurotransmitter Agents / Q000737:chemistry*; D017382:Reactive Oxygen Species / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D018377:Neurotransmitter Agents; D017382:Reactive Oxygen Species; D006859:Hydrogen