Tenectin, a novel extracellular matrix protein expressed during Drosophila melanogaster embryonic development.
During Drosophila embryonic development, various morphogenetic processes require the remodeling of the extracellular matrix. In a previous study, we have identified and characterized a cDNA encoding a novel putative extracellular matrix protein named tenebrin, in the beetle Tenebrio molitor. Here, we examine the expression of the Drosophila ortholog, referred to as Tenectin (Tnc), during embryonic development. Tnc is expressed in the majority of tissues of neuroectodermic origin such as hindgut, foregut, tracheal system, anal plate, and CNS. In the CNS, the Tnc transcript is restricted to a few cells, whereas the protein is located in the dorsal part of the axonal tracts. In the hindgut and the trachea, Tnc protein is expressed on the apical pole of the cells. Tnc is an extracellular matrix protein secreted in a polarized way in different organs of Drosophila embryos.
Fraichard
Stéphane
S
UMR CNRS 5548, Développement, Communication Chimique, 6 Bd Gabriel, 21000 Dijon, France.
Bouge
Anne-Laure
AL
Chauvel
Isabelle
I
Bouhin
Hervé
H
D000818:Animals; D002490:Central Nervous System / Q000196:embryology / Q000378:metabolism; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000196:embryology* / Q000378:metabolism*; D004625:Embryo, Nonmammalian; D047108:Embryonic Development; D016326:Extracellular Matrix Proteins / Q000378:metabolism*; D005775:Gastrula / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D008954:Models, Biological; D014132:Trachea / Q000166:cytology / Q000196:embryology / Q000378:metabolism
D029721:Drosophila Proteins; D016326:Extracellular Matrix Proteins; C515512:Tnc protein, Drosophila