title: [Microdialysis of cutaneous free flaps to monitor results of maxillofacial surgery].
abstract: The development of in vivo microdialysis has made it possible to monitor cutaneous free flaps in maxillo-facial surgery. A microprobe inserted in the free flap dermis collects a microdialysate enabling measurement of dermal metabolites such as glucose, lactate, pyruvate, or glycerol. The monitoring curves are predictive of ischemia-related tissue injury. Hourly measurements provide a reliable method for early diagnosis of venous or arterial thrombosis. Revision surgery can then be undertaken if needed to repair microanastomoses before clinical alteration. This technique has been compared with validated flaps monitoring systems such as temperature probe, transcutaneous oxygen tension monitoring, and laser Doppler flowmetry. Microdialysis has several advantages: objective measurements, different curves for venous and arterial thrombosis, early diagnosis. Accessibility to oral cavity or pharyngeal flaps requires careful clinical analysis (microprobe fixation, anatomy and choice of flap).
authors.affiliation: Service de Chirurgie Maxillo-faciale et Stomatologie, CHU Jean Minjoz, Besançon.
authors.forename: M
authors.initials: M
authors.lastname: Brix
authors.forename: P
authors.initials: P
authors.lastname: Muret
authors.forename: S
authors.initials: S
authors.lastname: Mac-Mary
authors.forename: B
authors.initials: B
authors.lastname: Ricbourg
authors.forename: P
authors.initials: P
authors.lastname: Humbert
mesh_terms: D006801:Humans; D017078:Laser-Doppler Flowmetry; D017551:Microdialysis / Q000379:methods*; D008991:Monitoring, Physiologic; D019647:Oral Surgical Procedures; D019651:Plastic Surgery Procedures; D012881:Skin Temperature / Q000502:physiology; D016038:Skin Transplantation / Q000000981:diagnostic imaging / Q000473:pathology*; D013524:Surgical Flaps / Q000473:pathology*; D014463:Ultrasonography