Familial occurrence of pulmonary alveolar microlithiasis in 3 siblings.
Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by intra-alveolar calcium deposits. More than 500 cases were reported in the literature. The disorder affects people at every age beginning from the early childhood. It occurs probably as a result of autosomal recessive transmission. Familial occurrence is often found with family history of the disease being present in up to 50% of the reported cases. We report PAM in 3 siblings.
Al-Alawi
Alia S
AS
Department of Medicine, Amiri Hospital, Kuwait. aliamed@yahoo.com
D000328:Adult; D006801:Humans; D020347:Lithiasis / Q000235:genetics*; D008171:Lung Diseases / Q000235:genetics; D008297:Male; D011650:Pulmonary Alveoli