title: Quality control of Cordyceps sinensis, a valued traditional Chinese medicine.
abstract: Cordyceps sinensis, a well-known and valued traditional Chinese medicine, is also called DongChongXiaCao (winter worm summer grass) in Chinese. It is commonly used to replenish the kidney and soothe the lung for the treatment of fatigue, night sweating, hyposexualities, hyperglycemia, hyperlipidemia, asthemia after severe illness, respiratory disease, renal dysfunction and renal failure, arrhythmias and other heart disease, and liver disease. As the rarity and upstanding curative effects of natural Cordyceps, several mycelial strains have been isolated from natural Cordyceps and manufactured in large quantities by fermentation technology, and they are commonly sold as health food products in Asia. In addition, some substitutes such as Cordyceps militaris also have been used and adulterants also confused the market. Therefore, quality control of C. sinensis and its products is very important to ensure their safety and efficacy. Herein, markers and analytical methods for quality control of Cordyceps were reviewed and discussed.
authors.affiliation: Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR, China. SPLI@UMAC.MO
authors.forename: S P
authors.initials: SP
authors.lastname: Li
authors.forename: F Q
authors.initials: FQ
authors.lastname: Yang
authors.forename: Karl W K
authors.initials: KW
authors.lastname: Tsim
mesh_terms: D000596:Amino Acids / Q000032:analysis; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D032661:Cordyceps / Q000737:chemistry*; D003470:Culture Media; D019075:Electrophoresis, Capillary; D004875:Ergosterol / Q000032:analysis; D008353:Mannitol / Q000032:analysis; D008516:Medicine, Chinese Traditional / Q000592:standards*; D010455:Peptides / Q000032:analysis; D011134:Polysaccharides / Q000032:analysis; D011786:Quality Control; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000596:Amino Acids; D003470:Culture Media; D010455:Peptides; D011134:Polysaccharides; D008353:Mannitol; D004875:Ergosterol