[Age specific reference ranges and clinical trial for complexed prostate specific antigen (cPSA)].
We compared the complexed PSA (cPSA) reference range of values by age against that for total PSA. The subjects were 1,210 men who underwent a complete medical checkup at our center between September and November 2003. We found an upward trend of the measured values associated with age and defined a set of expected result range by age groups. The cPSA 95th percentile upper limit value increased across all age groups: for men under 40 years, 1.38ng/ml: for men 40 to 49 years, 1.60ng/ml; for men 50 to 59 years, 2.25 ng/ml; for men 60 to 69 years, 2.50 ng/ml; and for men 70 years older, 4.31 ng/ml (The number of subjects in each group was 153, 323, 429, 220 and 77). The total PSA also increased with age: 1.85 ng/ml, 2.11 ng/ml, 2.80 ng/ml, 4.20 ng/ml, and 5.69 ng/ml, respectively. We also compared other prostatic tumor markers in urology patients.
Haga
Riichi
R
Central Clinical Laboratory, Mitsui Memorial Hospital, Chiyoda-ku, Tokyo 101-8643.
Shimomura
Hiroji
H
Ishizakaa
Yuko
Y
Yamakado
Minoru
M
Yamaguchi
Kazumi
K
Tominaga
Takashi
T
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000032:analysis*; D012016:Reference Values; D012680:Sensitivity and Specificity
D017430:Prostate-Specific Antigen