title: Perchlorate in water via US Environmental Protection Agency Method 331 Determination of method uncertainties, lowest concentration minimum reporting levels, and Hubaux-Vos detection limits in reagent water and simulated drinking water.
abstract: US Environmental Protection Agency (EPA) Method 331 determines perchlorate in drinking water using non-suppressed ion chromatography with tandem mass spectrometry. This study reports the results of calibration and recovery studies in reagent water, as well as of a recovery study in simulated drinking water (i.e., total dissolved solids are 500 mg/mL each of chloride, sulfate, and bicarbonate). The perchlorate concentrations in the study ranged from 0.05 to 64 ng/mL. At 95% confidence, the Hubaux-Vos detection limit (H-V DL) was 0.04 ng/mL for the calibration study and the simulated-drinking-water recovery study, and 0.03 ng/mL for the reagent-water recovery study. The lowest concentration minimum reporting level was 0.03 ng/mL for reagent water and 0.0 7 ng/mL for simulated drinking water, again at 95% confidence.
authors.affiliation: US Environmental Protection Agency, Cincinnati, OH, USA.
authors.forename: S C
authors.initials: SC
authors.lastname: Wendelken
authors.forename: L E
authors.initials: LE
authors.lastname: Vanatta
authors.forename: D E
authors.initials: DE
authors.lastname: Coleman
authors.forename: D J
authors.initials: DJ
authors.lastname: Munch
mesh_terms: D002138:Calibration; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods / Q000592:standards; D017408:Guidelines as Topic; D007477:Ions / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods; D010472:Perchlorates / Q000032:analysis* / Q000592:standards; D012015:Reference Standards; D012044:Regression Analysis; D015203:Reproducibility of Results; D014481:United States; D014484:United States Environmental Protection Agency; D014881:Water Supply / Q000032:analysis*
chemical_list: D007477:Ions; D010472:Perchlorates; C494474:perchlorate