Levels and distribution of polybrominated diphenyl ethers in various tissues of birds of prey.
In the present study, concentrations and tissue distribution of polybrominated diphenyl ethers (PBDEs; IUPAC # 28, 47, 99, 100, 153, 154, 183, and 209) were examined in brain, adipose tissue, liver, muscle, and serum of birds of prey. Median SigmaPBDE levels (BDE 28-183) in the tissues of sparrowhawks ranged from 360 to 1900 ng/g lipid weight (lw), which was in general one order of magnitude higher than in the tissues of common buzzards (26-130 ng/g lw). There were no differences in PBDE congener patterns between the various tissues within individuals of a certain species. Inter-species differences in PBDE patterns and in particular the percentage of BDE 99, 100 and 153 were, however, pronounced between sparrowhawk and common buzzard. BDE 209 was detected in nearly all serum and in some liver samples, but not in any other tissues. This observation suggests that exposure to BDE 209 is low or that this congener is poorly accumulated. Passive (lipid content related) diffusion could not completely describe the PBDE tissue distribution, e.g. the lowest PBDE-load was measured in brain, a fairly lipid rich tissue.
Voorspoels
Stefan
S
Department of Pharmacy, Toxicology Division, University of Antwerp, CDE--gebouw S, Universiteitsplein 1, B-2610 Wilrijk, Belgium. stefan.voorspoels@ua.ac.be <stefan.voorspoels@ua.ac.be>
Covaci
Adrian
A
Lepom
Peter
P
Jaspers
Veerle L B
VL
Schepens
Paul
P
D000273:Adipose Tissue / Q000737:chemistry; D000818:Animals; D001530:Belgium; D001717:Birds / Q000378:metabolism*; D001923:Brain Chemistry; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis* / Q000097:blood; D005411:Flame Retardants / Q000032:analysis; D055768:Halogenated Diphenyl Ethers; D008055:Lipids / Q000032:analysis / Q000737:chemistry; D008099:Liver / Q000737:chemistry; D009132:Muscles / Q000737:chemistry; D010647:Phenyl Ethers / Q000032:analysis; D011075:Polybrominated Biphenyls / Q000032:analysis* / Q000097:blood; D011235:Predatory Behavior; D013057:Spectrum Analysis
C477694:2,2',4,4',5-brominated diphenyl ether; D004785:Environmental Pollutants; D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; D008055:Lipids; D010647:Phenyl Ethers; D011075:Polybrominated Biphenyls; C517828:hexabrominated diphenyl ether 153; C517827:pentabrominated diphenyl ether 100; C010902:decabromobiphenyl ether