Aggressive angiomyxoma of the vulva or perineum: report of three patients.
BACKGROUND
Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumour that chiefly involves the vulvoperineal region of young female patients. Treatment is wide surgical excision. Frequent relapses are common.


METHODS
We present three patients who each had an aggressive angiomyxoma treated initially for another presumed diagnosis. Two patients required immediate repeat surgical procedures for incomplete tumour excision. The third patient developed a recurrence two years after the initial surgery. In one patient, hormonal therapy was used postoperatively because the evaluation of the tumour margins was uncertain. Harpoon markers were used to aid in tumour localization in another patient prior to resection.


CONCLUSIONS
Clinicians should consider the diagnosis of aggressive angiomyxoma when a patient presents with an atypical vulvoperineal mass, as an incorrect diagnosis may lead to repeated surgical procedures.
Alobaid
Abdulaziz
A
Department of Gynecology Oncology, Notre-Dame Hospital, CHUM, University of Montreal, Montreal, QC.
Goffin
Frédéric
F
Lussier
Christian
C
Drouin
Pierre
P
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009232:Myxoma / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D010502:Perineum / Q000473:pathology; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000473:pathology / Q000601:surgery*