title: [Quality of life assessment in osteoporotic patients with and without vertebral fractures].
abstract: BACKGROUND
  Vertebral fractures are assotiated with back pain and disability, but relatively little is known about their impact on quality of life of these patients. The aim of the study was to compare the quality of life of osteoporotic patients with and without vertebral fractures.
  
  
  METHODS
  Bone mineral density measurement was done by dual-energy X-ray absorptiometry using LUNAR DPX-L in patients with osteoporosis divided into 2 groups: Group I (33 patients) with and Group II (30 patients) without vertebral fractures. Quality of life assessment was done using the Qualeffo-41. Statistical analysis was done using student t-test and Mann-Whitney U test.
  
  
  RESULTS
  The results of Qualeffo-41 questionnaire suggest highly significant differences in quality of life between patients with and patients without vertebral fractures (p<0.001). Impaired quality of life in patients with vertebral fractures was evident in all domains of the questionnaire: pain (p=0.017), activities of daily living (p<0.001), jobs around the house (p=0.007), mobility (p<0.001), leisure, social activities (p=0.002), general health perception (p=0.002) and mental function (p=0.025).
  
  
  CONCLUSIONS
  Health-related quality of life may be assessed using generic or disease-specific instruments. The Qualeffo-41 questionnaire is a disease-specific instrument which was developed by a working group of the European Foundation for Osteoporosis and has a great face and content validity in assessing quality of life in osteoporotic patients.
  
  
  CONCLUSIONS
  Osteoporotic patients with vertebral fractures have a significantly impaired quality of life compared with osteoporotic patients without vertebral fractures.
authors.affiliation: Medicinski fakultet, Beograd, Institut za reumatologiju. Stuparn@eunet.yu
authors.forename: Nada
authors.initials: N
authors.lastname: Vujasinović-Stupar
authors.forename: Goran
authors.initials: G
authors.lastname: Radunović
authors.forename: Medija
authors.initials: M
authors.lastname: Smailji
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D005260:Female; D050815:Fractures, Compression / Q000209:etiology*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications*; D015663:Osteoporosis, Postmenopausal / Q000150:complications*; D011788:Quality of Life; D016103:Spinal Fractures / Q000209:etiology*; D011795:Surveys and Questionnaires