Sequential ring closing/opening metathesis for the highly selective synthesis of a triply bifunctionalized alpha-cyclodextrin.
Metathesis versatility has been exploited to reveal the cyclic directionality of cyclodextrins and to selectively synthesise a unique cyclodextrin bearing three pairs of orthogonal protecting groups on its primary rim.
Bistri
Olivia
O
Ecole Normale Supérieure, Département de Chimie, Institut de chimie moléculaire (FR 2769), UMR 8642: CNRS-ENS-UPMC Paris 6, 24 rue Lhomond, 75231, Paris Cedex 05, Paris, France.
Sinaÿ
Pierre
P
Sollogoub
Matthieu
M
D015394:Molecular Structure; D012680:Sensitivity and Specificity; D047391:alpha-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry*
D047391:alpha-Cyclodextrins; C032613:alpha-cyclodextrin