[Pregnancy after renal transplantation. Obstetrical follow-up and impact on renal graft function].
OBJECTIVE
The aim of this study is to give the results of our experience about pregnancies among the renal transplantation patients and to assess the impact of the pregnancy on renal graft function.


METHODS
Twenty pregnancies from 17 renal transplant recipients were analysed and long-term outcome of the renal graft was studied. We analysed the outcomes from clinical and biological data before, during and after pregnancy.


RESULTS
Mean patient age was 30.3+/-3.5 years and meantime between transplantation and the onset of pregnancy was 62.4+/-34.5 months. There was no significant difference between the biological data before and after pregnancy. We did not observe any acute rejection. The mean maternal complications were preeclampsia in 35%, low birth weight in 39%, prematurity in 45% and cesarean sections in 55%. There is no impact of the pregnancy on the renal graft during the follow-up (3 years). The follow-up revealed 2 cases of chronic rejection.


CONCLUSIONS
A multi-disciplinary approach of pregnancy in renal recipients and an interval of 2 years after kidney transplantation are necessary. There are more complications during pregnancy without increased risks of graft lose.
Ducarme
G
G
Service de gynécologie-obstétrique, AP-HP, CHU Jean-Verdier, avenue du 14-Juillet, 93143 Bondy cedex, France. g.ducarme@gmail.com
Ceccaldi
P-F
PF
Toupance
O
O
Graesslin
O
O
Rieu
P
P
Gabriel
R
R
D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000009:adverse effects; D007752:Obstetric Labor, Premature / Q000453:epidemiology / Q000209:etiology; D011225:Pre-Eclampsia / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000209:etiology; D011256:Pregnancy Outcome; D013997:Time Factors