[Microbiological non-culture methods for the diagnosis of invasive candidiasis: usefulness of surrogate markers].
The usefulness of surrogate markers in the diagnosis of invasive candidiasis is based on their ability to detect the infection caused by the different Candida spp. and to differentiate when the fungus is a colonizer or it is causing an invasive disease. This differentiation has been tried by detecting antigens, antibodies and other Candida components in the patient's sera. In this paper we will review the antigens, antibodies and other Candida components which may be useful in the laboratory diagnosis of invasive candidiasis in the non-neutropenic critically ill patient.
Pontón
José
J
Dpto. Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apdo. 699, 48080 Bilbao, Spain. jose.ponton@ehu.es
D015415:Biomarkers / Q000097:blood; D002177:Candidiasis / Q000097:blood* / Q000175:diagnosis*; D016638:Critical Illness; D006801:Humans
D015415:Biomarkers