title: Beyond Mfold: recent advances in RNA bioinformatics.
abstract: Computational analysis of RNA secondary structure is a classical field of biosequence analysis, which has recently gained momentum due to the manyfold regulatory functions of RNA that have become apparent. We present five recent computational approaches that address the problems of synoptic folding space analysis, pseudoknot prediction, structure alignment, comparative structure prediction, and miRNA target prediction. All these programs are in current use and are available via the Bielefeld Bioinformatics Server at .
authors.affiliation: Faculty of Technology, Bielefeld University, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Reeder
authors.forename: Matthias
authors.initials: M
authors.lastname: Höchsmann
authors.forename: Marc
authors.initials: M
authors.lastname: Rehmsmeier
authors.forename: Björn
authors.initials: B
authors.lastname: Voss
authors.forename: Robert
authors.initials: R
authors.lastname: Giegerich
mesh_terms: D000818:Animals; D001483:Base Sequence; D019295:Computational Biology / Q000639:trends*; D006801:Humans; D020407:Internet; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D012689:Sequence Homology, Nucleic Acid; D012984:Software
chemical_list: D012313:RNA