[Estimation of postmortem interval using myofibril fragmentation index].
OBJECTIVE
To study the relationship between postmortem interval and the myofibril fragmentation index of skeletal muscle.


METHODS
Rabbit skeletal muscle were left in the room temperature for different postmortem intervals, and the protein concentration of each sample was detected by using biuret method. Furthermore, the myofibril fragmentation index of each sample was measured under the protein concentration level of 0.5 mg/mL.


RESULTS
The myofibril fragmentation index increased obviously according to the postmortem interval prolongation.


CONCLUSIONS
The myofibril fragmentation index may be used on the estimation of early postmortem interval.
Wu
Rong-qi
RQ
Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032,China. wurongqi@gmail.com
Zhao
Zi-qin
ZQ
Shen
Yi-wen
YW
Jia
Jian-zhang
JZ
D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism; D005260:Female; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D009210:Myofibrils / Q000378:metabolism*; D011180:Postmortem Changes; D011506:Proteins / Q000378:metabolism*; D011817:Rabbits; D013053:Spectrophotometry; D013997:Time Factors
D002135:Calcium-Binding Proteins; D011506:Proteins; C033668:calpastatin