title: [Clinical guide to the management of patients with Beckwith-Wiedemann syndrome].
abstract: Beckwith-Wiedemann syndrome (BWS) is characterized by congenital overgrowth, macroglossia and omphalocele or umbilical hernia. Children with BWS may also have all or some of the following features: asymmetry (hemihypertrophy) of the limbs, torso or face, hypoglycemia, organomegaly, ear pits or creases, and embryonal tumors. The frequency of BWS is approximately 1:14,000 births. We present a guide for the management of children with BWS aimed at helping pediatricians and general practitioners or specialists in the clinical follow-up of these patients. This guide has been structured according to different age groups and is based on published evidence.
authors.affiliation: Servicio de Genética Médica, Hospital Universitario La Paz, Madrid, Spain. plapunzina.hulp@salud.madrid.org
authors.forename: P
authors.initials: P
authors.lastname: Lapunzina Badía
authors.forename: M
authors.initials: M
authors.lastname: del Campo Casanelles
authors.forename: A
authors.initials: A
authors.lastname: Delicado Navarro
authors.forename: J
authors.initials: J
authors.lastname: Fernández-Toral
authors.forename: A
authors.initials: A
authors.lastname: García-Alix
authors.forename: L
authors.initials: L
authors.lastname: García-Guereta
authors.forename: L A
authors.initials: LA
authors.lastname: Pérez Jurado
authors.forename: F J
authors.initials: FJ
authors.lastname: Ramos Fuentes
authors.forename: A
authors.initials: A
authors.lastname: Sánchez Díaz
authors.forename: M
authors.initials: M
authors.lastname: Urioste Azcorra
mesh_terms: D000293:Adolescent; D001506:Beckwith-Wiedemann Syndrome / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn