title: Study of serum lipid profile in type 2 diabetic patients attending KMCTH.
abstract: The study was aimed at identifying the association between two major risk factors for coronary artery disease (CAD), namely, type 2 diabetes and hyperlipidemia. Hyperlipidemia has a ocumented causative relation with CAD, but the major risk associated with diabetes may be due to the associated hyperlipidemia. Lipid profiles of 30 patients with type 2 diabetes were taken and a detailed clinical workup done, including estimation of the body mass index (BMI). The study revealed that dyslipidemia is very common in type 2 diabetics and the most common abnormality seen was increased serum triglyceride levels (73.3%). The next common abnormality was decreased serum high-density lipoprotein cholesterol (HDL-C) levels and increased serum low-density lipoprotein cholesterol (LDL-C) levels, both seen in 66.7% patients respectively. A high total serum cholesterol levels was seen in 46.7% patients. Forty percent of the patients examined were on the overweight side, 16.7% being overtly obese. Thus the study, despite having small number of patients, clearly shows the association between type 2 diabetes and hyperlipidemia, which may influence the mechanism by which type 2 diabetes is associated with increased CAD risk.
authors.affiliation: Department of Medicine, Kathmandu Medical College Teaching Hospital, Nepal. kcmathura@wlink.com.np
authors.forename: K C
authors.initials: KC
authors.lastname: Mathura
authors.forename: Binit
authors.initials: B
authors.lastname: Vaidya
authors.forename: Dipesh Lal
authors.initials: DL
authors.lastname: Gurbacharya
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003324:Coronary Artery Disease / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000503:physiopathology*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D008055:Lipids