Sildenafil as treatment for Human Immunodeficiency Virus-related pulmonary hypertension in a child.
Human Immunodeficiency Virus (HIV)-related pulmonary hypertension is a relatively rare disease that can affect HIV sufferers. This is almost always associated with a poor outcome and death. An 18 month-old girl, probably the youngest on record, was diagnosed to have pulmonary hypertension (PHT) and retrospectively found to have HIV infection. Sildenafil was used to control her PHT and she remains alive even after 2 years.
Wong
Abdul Rahim
AR
Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan. rahim@kck.usm.my
Rasool
Aida Hanum G
AH
Abidin
Nik Zainal
NZ
Noor
Abdul Rahmand
AR
Quah
Ban Seng
BS
D006332:Cardiomegaly / Q000150:complications; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D007223:Infant; D010879:Piperazines / Q000008:administration & dosage* / Q000627:therapeutic use; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate