Double functionalization of carbon nanotubes for multimodal drug delivery.
Multi-walled carbon nanotubes have been covalently functionalized via 1,3-dipolar cycloaddition of azomethine ylides with orthogonally protected amino functions that can be selectively deprotected and subsequently modified with drugs and fluorescent probes.
Pastorin
Giorgia
G
Institut de Biologie Moléculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France.
Wu
Wei
W
Wieckowski
Sébastien
S
Briand
Jean-Paul
JP
Kostarelos
Kostas
K
Prato
Maurizio
M
Bianco
Alberto
A
D001391:Azo Compounds / Q000737:chemistry*; D003500:Cyclization; D004337:Drug Carriers / Q000737:chemistry*; D016252:Microscopy, Scanning Tunneling; D037742:Nanotubes, Carbon / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D012995:Solubility
D001391:Azo Compounds; D004337:Drug Carriers; D037742:Nanotubes, Carbon; D004364:Pharmaceutical Preparations