title: [Supportive antisecretory therapy in preventing duodenal ulcer recurrence].
abstract: Different points of view on the need to conduct supportive acid-suppressive therapy gave rise to this study. The study is aimed at evaluating the influence of the individual supportive therapy based on the results of intragastric pH-monitoring on the incidence of duodenal ulcers. The study is based on a two-year observation of 90 patients with duodenal ulcers. After the ulcers had scarred and the patients had been discharged from hospital, all the patients were divided into three groups for undergoing a follow-up supportive acid-suppressive therapy. As a result, it was revealed that the individually selected supportive antisecretory therapy controlled by intragastric pH-monitoring within two years of observation made it possible to reduce considerably the incidence of duodenal ulcer recurrence in comparison with traditional preventive treatment.
authors.forename: I A
authors.initials: IA
authors.lastname: Sholomitskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Kapralov
authors.forename: N F
authors.initials: NF
authors.lastname: Soroka
mesh_terms: D000293:Adolescent; D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000503:physiopathology*; D004386:Duodenum / Q000187:drug effects* / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D000897:Anti-Ulcer Agents