title: Effect of high-intensity inspiratory muscle training on lung volumes, diaphragm thickness, and exercise capacity in subjects who are healthy.
abstract: OBJECTIVE
  Previous investigations have demonstrated that a regimen of high-intensity inspiratory muscle training (IMT) resulted in changes in ventilatory function and exercise capacity in patients with chronic lung disease, although the effect of high-intensity IMT in subjects who are healthy is yet to be determined. The purpose of this study, therefore, was to examine whether high-intensity IMT resulted in changes in ventilatory function and exercise capacity in subjects who were healthy.
  
  
  METHODS
  Twenty subjects were randomly assigned to 2 groups.
  
  
  METHODS
  The training group completed an 8-week program of IMT set at 80% of maximal effort. The control group did not participate in any form of training. Baseline and posttraining measures of body composition, pulmonary function, inspiratory muscle function (including maximal and sustained maximal inspiratory pressures [MIP and SMIP]), relaxed and contracted diaphragm thickness and thickening ratio (Tdi.rel, Tdi.cont, and TR), and exercise capacity were determined.
  
  
  RESULTS
  The training group demonstrated significant increases in MIP, SMIP, Tdi.cont, TR, VC, total lung capacity, and exercise capacity compared with the control group, which demonstrated no change from baseline measurements at 8 weeks.
  
  
  CONCLUSIONS
  The findings of this study suggest that high-intensity IMT results in increased contracted diaphragm thickness and increased lung volumes and exercise capacity in people who are healthy.
authors.affiliation: School of Healthcare Studies, Cardiff University, Ty Dewi Sant, Heath Park, Cardiff CF14 4XN, UK. enrights@cardiff.ac.uk
authors.forename: Stephanie J
authors.initials: SJ
authors.lastname: Enright
authors.forename: Viswanath B
authors.initials: VB
authors.lastname: Unnithan
authors.forename: Clare
authors.initials: C
authors.lastname: Heward
authors.forename: Louise
authors.initials: L
authors.lastname: Withnall
authors.forename: David H
authors.initials: DH
authors.lastname: Davies
mesh_terms: D000328:Adult; D001945:Breathing Exercises; D003964:Diaphragm / Q000033:anatomy & histology / Q000502:physiology; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006801:Humans; D001239:Inhalation / Q000502:physiology*; D008176:Lung Volume Measurements; D008297:Male; D009929:Organ Size; D012132:Respiratory Muscles / Q000502:physiology*