title: [Clinical significance of prostatic-specific antigen levels in patients with benign prostatic hyperplasia complicated by low urinary tract syndrome].
abstract: OBJECTIVE
  To evaluate the clinical significance of prostatic-specific antigen (PSA) levels in patients with benign prostatic hyperplasia (BPH) complicated by low urinary tract syndrome( LUTS).
  
  
  METHODS
  The levels of tPSA, fPSA and fPSA/tPSA ratio were detected and compared in 520 cases of BPH with LUTS and 196 cases without LUTS.
  
  
  RESULTS
  The mean levels of tPSA in the cases of BPH with LUTS and without LUTS were (5.13 +/- 2.49) microg/L and (1.73 +/- 1.26) microg/L respectively (P<0.01). The mean levels fPSA were (1.57 +/- 0.80) microg/L and (0.54 +/- 0.38) microg/L respectively (P < 0.01). The mean ratios of fPSA/tPSA were (0.31 +/- 0.09) and (0.30 +/- 0.11) respectively ( P > 0.05).
  
  
  CONCLUSIONS
  The levels of tPSA, fPSA are significantly higher in the cases of BPH with LUTS than those in the cases without LUTS, but the ratio of fPSA/tPSA is stable in BPH.
authors.affiliation: Department of Urology, Xinhua Hospital, Shanghai Jiao Tong University Medical College, Shanghai 200092, China.
authors.forename: Ying-Jian
authors.initials: YJ
authors.lastname: Zhu
authors.forename: Min
authors.initials: M
authors.lastname: Ye
authors.forename: Wei-Ming
authors.initials: WM
authors.lastname: Wang
authors.forename: Hai-Bo
authors.initials: HB
authors.lastname: Shen
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Chen
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000150:complications; D012680:Sensitivity and Specificity; D014522:Urethral Diseases / Q000209:etiology
chemical_list: D017430:Prostate-Specific Antigen