Protective immunity against hepatitis C virus infection.
There is increasing evidence that a small percentage of individuals exposed to the hepatitis C virus have the capacity to generate a strong cellular immune response against the virus and avoid persistent infection, and perhaps do so repeatedly after re-exposure. This article reviews the evidence that the responses identified in this unique group of individuals represent the protective immunity that will need to be elicited by hepatitis C virus vaccines.
Elliot
Lisa N
LN
School of Women's and Children's Health, The University of New South Wales, Sydney, New South Wales, Australia.
Lloyd
Andrew R
AR
Ziegler
John B
JB
Ffrench
Rosemary A
RA
D000917:Antibody Formation; D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000502:physiology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014611:Vaccination; D014761:Viral Hepatitis Vaccines
D014761:Viral Hepatitis Vaccines