[Effect of sodium hypochlorite on the biotransformation of toxicants in acute poisoning by psychotropic agents].
In acute poisoning by amitriptyline, carbazepine, barbiturates, and ethanol, the effect of sodium hypochlorite on the metabolism of toxicants is manifested as a considerable reduction in their high blood concentrations through oxidative transformation to inactive water-soluble derivatives and as the enhanced urinary elimination of the latter. The rate of the above process depends on the used dose of sodium hypochlorite.
Petrov
S I
SI
Belova
M V
MV
Luzhnikov
E A
EA
Gol'dfarb
Iu S
IuS
Il'iashenko
K K
KK
Lisovik
Zh A
ZhA
Baturova
I V
IV
Popova
M M
MM
El'kov
A N
AN
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008658:Inactivation, Metabolic; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000008:administration & dosage*; D010084:Oxidation-Reduction; D011619:Psychotropic Drugs / Q000097:blood / Q000378:metabolism* / Q000506:poisoning*; D012973:Sodium Hypochlorite / Q000008:administration & dosage*
D016877:Oxidants; D011619:Psychotropic Drugs; D012973:Sodium Hypochlorite