title: Modulation of visual stimulus discrimination by sustained focal attention: an MEG study.
abstract: OBJECTIVE
  Visual attention, normally focused on the center of the visual field, can be shifted to a location in the periphery. This process facilitates the recognition of objects in the attended region. The present experiment was designed to investigate the time course of sustained attention that is known to augment stimulus perception in normal subjects.
  
  
  METHODS
  Cortical activity of the human brain related to shifts of the attentional focus was examined with magnetoencephalography. Subjects had to identify a stimulus presented on a screen at one of two locations in the periphery of their visual fields. Sustained attention was either deployed toward the target by a preceding cue or not.
  
  
  RESULTS
  Results confirmed a reaction time advantage on recognizing objects in the part of the visual field where attention had been deployed. A stronger magnetic brain response was detected for noncued targets at a latency of 260 to 380 ms after target onset. Source localization revealed a neuronal generator of the attention-related component in the parietal cortex.
  
  
  CONCLUSIONS
  Sustained attention facilitates target detection. The component that is localized in the parieto-occipital cortex in the noncued condition is thought to reflect a transient shift of attention toward the target location.
authors.affiliation: MEG Centre, University of Tübingen, Germany.
authors.forename: Karin S
authors.initials: KS
authors.lastname: Pilz
authors.forename: Christoph
authors.initials: C
authors.lastname: Braun
authors.forename: Elke
authors.initials: E
authors.lastname: Altpeter
authors.forename: Manfred
authors.initials: M
authors.lastname: Mackeben
authors.forename: Susanne
authors.initials: S
authors.lastname: Trauzettel-Klosinski
mesh_terms: D000328:Adult; D001288:Attention; D003463:Cues; D016002:Discriminant Analysis; D005260:Female; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008297:Male; D010296:Parietal Lobe / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*