Anthropometric features and cardiovascular risk in young Latin Americans with type 2 diabetes mellitus.
OBJECTIVE
The purpose of this study is to compare score systems used to estimate the risk for cardiovascular disease (CVD) in young patients with poorly controlled type 2 diabetes.


METHODS
Fifty-seven Latin American patients with type 2 diabetes, between the ages 18 and 45 years, were screened to participate in a clinical research study evaluating the effects of intensive insulin therapy on both traditional and nontraditional CVD risk factors. All women were premenopausal and had regular menstrual periods. Baseline reviews of cardiovascular (CV) risk scores, personal history, physical examination, and laboratory screening were performed. The Framingham Study Score system and the presence of features of the metabolic syndrome (MSyn) were recorded and compared.


RESULTS
Both genders had a comparable number of features of the MSyn, whereas according to the Framingham Score System, men had a slightly higher risk of CVD.


CONCLUSIONS
The Framingham Score system is not an accurate device to estimate risk of CVD in premenopausal women with type 2 diabetes mellitus, who otherwise have a multiple features of the MSyn. If used to estimate risk of CVD, the Framingham score system could underestimate the risk of CVD in both young men and women with type 2 diabetes mellitus.
Avilés-Santa
Larissa
L
Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, TX 75390-8858, USA. maines.aviles-santa@utsouthwestern.edu
Salinas
Karin
K
Adams-Huet
Beverley
B
Raskin
Philip
P
D000293:Adolescent; D000328:Adult; D001837:Body Weights and Measures; D002318:Cardiovascular Diseases / Q000208:ethnology* / Q000209:etiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000208:ethnology*; D005260:Female; D006442:Glycated Hemoglobin; D006305:Health Status Indicators; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000208:ethnology; D008875:Middle Aged; D009765:Obesity; D017697:Premenopause; D018570:Risk Assessment / Q000379:methods / Q000592:standards; D012737:Sex Factors; D013781:Texas / Q000453:epidemiology
D006442:Glycated Hemoglobin