Transarterial embolization of vein of Galen malformations: the use of magnetic resonance imaging noninvasive optimal vessel analysis to quantify shunt reduction. Report of two cases.
In patients with vein of Galen malformations, high-flow shunting decreases cerebral perfusion. By reducing or eliminating these shunts, transarterial embolization can improve cerebral perfusion and clinical outcomes. Quantifying pre- and postembolization shunt blood flow may help determine the optimal timing and efficacy of embolization and may provide prognostic information. The authors used magnetic resonance imaging noninvasive optimal vessel analysis as a novel modality to measure volumetric blood flow through vein of Galen malformation shunts in a neonate and an infant before and after transarterial embolization.
Langer
David J
DJ
Department of Neurosurgery, Hyman-Newman Institute for Neurology and Neurosurgery, Roosevelt Hospital, New York, New York 10019, USA.
Song
Joon K
JK
Niimi
Yasunari
Y
Chwajol
Markus
M
Lefton
Daniel R
DR
Brisman
Jonathan L
JL
Molofsky
Walter
W
Kupersmith
Mark J
MJ
Berenstein
Alejandro
A
D001921:Brain / Q000098:blood supply; D002550:Cerebral Veins / Q000002:abnormalities*; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D012039:Regional Blood Flow; D017287:Ventriculoperitoneal Shunt