Array-based methods for diagnosis and prevention of transplant rejection.
DNA microarray is a microhybridization-based assay that is used to simultaneously study the expression of thousands of genes, thus providing a global view of gene expression in a tissue sample. This powerful technique has been adopted by many biomedical disciplines and will likely have a profound impact on the diagnosis, treatment and prognosis of human diseases. This review article presents an overview of the application of microarray technology to the field of solid-organ transplantation.
Zhang
Qiuheng
Q
Immunogenetics Center, Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA. jqzhang@mednet.ucla.edu
Reed
Elaine F
EF
D018925:Chemokines / Q000378:metabolism; D006084:Graft Rejection / Q000175:diagnosis* / Q000517:prevention & control*; D016027:Heart Transplantation / Q000379:methods; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D016030:Kidney Transplantation / Q000379:methods; D016040:Lung Transplantation / Q000379:methods; D020782:Matrix Metalloproteinases / Q000378:metabolism; D025202:Molecular Diagnostic Techniques; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D013601:T-Lymphocytes / Q000378:metabolism
D018925:Chemokines; D007166:Immunosuppressive Agents; D020782:Matrix Metalloproteinases