title: Determinants of adherence to non-occupational post HIV exposure prophylaxis.
abstract: We conducted a study on 140 patients who sought advice at hospital after a non-occupational exposure. The full 28-day course of prophylactic antiretroviral therapy was completed by 109 patients. No HIV contamination was observed. Factors associated with suboptimal adherence were African ethnicity [odds ratio (OR) 13.3, 2.02-87.54] and oral sexual intercourse (OR 8.35, 1.66-41.99). Compliance with prophylactic antiretroviral therapy can be increased by addressing social and psychological barriers to adherence.
authors.affiliation: Service de Maladies Infectieuses et Tropicales, Paris, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Lacombe
authors.forename: Anne
authors.initials: A
authors.lastname: Daguenel-Nguyen
authors.forename: Véronique
authors.initials: V
authors.lastname: Lebeau
authors.forename: Laurent
authors.initials: L
authors.lastname: Fonquernie
authors.forename: Pierre-Marie
authors.initials: PM
authors.lastname: Girard
authors.forename: Marie-Caroline
authors.initials: MC
authors.lastname: Meyohas
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active; D044383:Black People / Q000523:psychology; D004334:Drug Administration Schedule; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology / Q000635:transmission; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000208:ethnology / Q000523:psychology*; D012725:Sexual Behavior
chemical_list: D019380:Anti-HIV Agents