Nonheart failure-associated elevation of amino terminal pro-brain natriuretic peptide in the setting of sepsis.
In addition to its importance in clinical assessment, N-terminal pro-brain natriuretic peptide (NT pro-BNP) is a valuable marker for evaluation of treatment and prognosis of heart failure. However, there are situations where NT pro-BNP is not related to myocardial dysfunction. Two cases of sepsis with markedly elevated NT pro-BNP levels that are not indicative of depressed myocardial function are described.
Bar
Simona L
SL
Healthy Heart Program, St Paul's Hospital, Vancouver, British Columbia.
Swiggum
Elizabeth
E
Straatman
Lynn
L
Ignaszewski
Andrew
A
D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011498:Protein Precursors / Q000097:blood; D018805:Sepsis / Q000097:blood* / Q000188:drug therapy
D015415:Biomarkers; D010446:Peptide Fragments; D011498:Protein Precursors; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain