title: Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression.
abstract: Six subjects with similar unilateral tinnitus that was fully suppressed by carbamazepine have been identified. Their ages at the time of the sudden onset of their tinnitus ranged from 39 to 87 years (mean 67). The 3 men had right ear tinnitus. Two of the 3 women had left ear tinnitus. All 6 described a staccato quality of their intermittent tinnitus ('like a typewriter in the background, pop corn, Morse code'). Five of the 6 subjects had no other hearing or vestibular complaints; their audiograms were symmetric and consistent with their ages. Vascular compression of the auditory nerve ipsilateral to the tinnitus was detected in 4 of the 5 subjects imaged. The similarities between typewriter tinnitus and other cranial nerve syndromes associated with vascular compression (trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia) suggest that surgical decompression of the auditory nerve can relieve medication-refractive cases of typewriter tinnitus.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, Eaton-Peabody Laboratory, Boston, MA 02114-3096, USA. ObbyLevine@yahoo.com
authors.forename: Robert Aaron
authors.initials: RA
authors.lastname: Levine
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002220:Carbamazepine / Q000627:therapeutic use; D003056:Cochlear Nerve / Q000473:pathology*; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000150:complications* / Q000601:surgery; D014012:Tinnitus / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D000160:Vestibulocochlear Nerve Diseases / Q000150:complications* / Q000601:surgery
chemical_list: D002220:Carbamazepine