title: [The effect of ethanol on sexual function of males and its mechanism].
abstract: Though an adequate volume of ethanol relieves nervousness and enhances sexual desire,long term and excessive intake of ethanol can induce sexual dysfunction. The reasons that ethanol results in sexual dysfunction are as follows: ethanol inhibits the hypothalamo-pituitary-testes axis and decreases serum testosterone level. The decline of smooth muscle, choline acetyltransferase and nitric oxide synthase in the penis may be responsible for it.
authors.affiliation: Department of Urology, the First Affiliated Hospital of Haerbin Medical University, Haerbin, Heilongriang 150001, China. ganxiuguo@yahoo.com.cn
authors.forename: Xiu-Guo
authors.initials: XG
authors.lastname: Gan
authors.forename: Rui-Hua
authors.initials: RH
authors.lastname: An
authors.forename: De-Bin
authors.initials: DB
authors.lastname: Zhong
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects*; D008297:Male; D019001:Nitric Oxide Synthase / Q000378:metabolism; D010413:Penis / Q000166:cytology* / Q000378:metabolism*; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013739:Testosterone / Q000097:blood
chemical_list: D000431:Ethanol; D013739:Testosterone; D019001:Nitric Oxide Synthase; D000110:Acetylcholinesterase