title: PIANA: protein interactions and network analysis.
abstract: We present a software framework and tool called Protein Interactions And Network Analysis (PIANA) that facilitates working with protein interaction networks by (1) integrating data from multiple sources, (2) providing a library that handles graph-related tasks and (3) automating the analysis of protein-protein interaction networks. PIANA can also be used as a stand-alone application to create protein interaction networks and perform tasks such as predicting protein interactions and helping to identify spots in a 2D electrophoresis gel.
  
  
  BACKGROUND
  PIANA is under the GNU GPL. Source code, database and detailed documentation may be freely downloaded from http://sbi.imim.es/piana.
authors.affiliation: Structural Bioinformatics Group (GRIB-IMIM), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain. ramon.aragues@upf.edu
authors.forename: Ramon
authors.initials: R
authors.lastname: Aragues
authors.forename: Daniel
authors.initials: D
authors.lastname: Jaeggi
authors.forename: Baldo
authors.initials: B
authors.lastname: Oliva
mesh_terms: D003196:Computer Graphics; D003628:Database Management Systems; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods*; D011506:Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins