title: Reconstructive materials and bone tissue engineering in implant dentistry.
abstract: Periodontal function for natural teeth and dental implants depends strongly on the mechanical integrity of the bone in the maxilla and mandible. Ongoing healthy bone remodeling around a natural tooth or implant is critical for longevity. Chemical factors that influence bone remodeling have been explored with the goal of enhancing the growth and maintenance of good quality bone. Less, but increasing, effort has been directed at understanding mechanical signals and factors, including those affected by implant/prosthesis materials that transmit loads directly to the surrounding bone. This article reviews research on the effects of synthetic materials and resulting mechanical stimuli on bone tissue engineering in dentistry.
authors.affiliation: Department of Biomedical Engineering, University of California, Irvine, CA 92697-2575, USA. earthman@uci.edu
authors.forename: James C
authors.initials: JC
authors.lastname: Earthman
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Lindsey R
authors.initials: LR
authors.lastname: VanSchoiack
authors.forename: Cherilyn G
authors.initials: CG
authors.lastname: Sheets
authors.forename: Jean C
authors.initials: JC
authors.lastname: Wu
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D016723:Bone Remodeling / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use*; D003758:Dental Implantation, Endosseous / Q000295:instrumentation / Q000379:methods*; D015921:Dental Implants; D003793:Dental Restoration, Permanent / Q000379:methods; D003799:Dental Stress Analysis; D006801:Humans; D008954:Models, Biological; D016348:Osseointegration / Q000502:physiology; D019651:Plastic Surgery Procedures / Q000295:instrumentation* / Q000379:methods; D023822:Tissue Engineering / Q000295:instrumentation / Q000379:methods*
chemical_list: D018786:Bone Substitutes; D015921:Dental Implants