Oral bowenoid papulosis in an HIV-positive male.
Bowenoid papulosis (BP) is a condition triggered by human papillomavirus infection and characterized by the development of 1 or more warty lesions, usually in the anogenital region. Although the oral cavity has been known to host several types of warts, thus far only 4 cases of BP have been reported in this anatomic site. We describe a 42-year-old male with AIDS who presented with numerous papillary lesions of the labial mucosa and vermilion. Biopsy yielded a diagnosis of BP. Treatment of the condition consisted of intralesional and subcutaneous injections of interferon-alpha followed by topical application of imiquimod 5% cream. Neither regimen resulted in resolution of the lesions. To our knowledge, this represents the first case of BP arising in the oral mucosa of an HIV-infected individual.
Rinaggio
Joseph
J
Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey-New Jersey Dental School, Newark, NJ 07103-2400, USA. rinaggjo@umdnj.edu
Glick
Michael
M
Lambert
W Clark
WC
D000328:Adult; D001913:Bowen's Disease / Q000150:complications* / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008048:Lip Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000150:complications* / Q000473:pathology
D004279:DNA, Viral