title: The effect of pre-eclampsia on complete blood count, platelet count and mean platelet volume.
abstract: Pre-eclampsia is a condition observed during pregnancy and threatens the life of both mother and foetus. There are studies, which suggest platelets play a major role in the pathogenesis of pre-eclampsia. The aim of this study is to compare the complete blood count (CBC) parameters, especially platelet count and mean platelet volume (MPV), in pre-eclamptic and normal pregnant women and to evaluate whether these parameters have a prognostic significance in determining the severity of eclampsia. The study and control groups consist of 56 pre-eclamptic and 43 normal pregnant women, respectively. There was no statistically significant difference according to CBC, platelet count and MPV when pre-eclamptic and severely pre-eclamptic patients were compared with controls. As a result, we observed no prognostic significance of CBC, platelet count and MPV on the presence and/or severity of pre-eclamptic condition. There are conflicting results especially on the significance of MPV in the literature, and possibly this confliction is due to the difference between methods and/or equipments used for automated blood count.
authors.affiliation: Departments of Obstetric and Gynecology, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Temel
authors.initials: T
authors.lastname: Ceyhan
authors.forename: Cengiz
authors.initials: C
authors.lastname: Beyan
authors.forename: Iskender
authors.initials: I
authors.lastname: Başer
authors.forename: Kürşat
authors.initials: K
authors.lastname: Kaptan
authors.forename: Sadettin
authors.initials: S
authors.lastname: Güngör
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ifran
mesh_terms: D000328:Adult; D048429:Cell Size; D005260:Female; D006801:Humans; D010976:Platelet Count; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy / Q000097:blood