title: Anthropometric features and cardiovascular risk in young Latin Americans with type 2 diabetes mellitus.
abstract: OBJECTIVE
  The purpose of this study is to compare score systems used to estimate the risk for cardiovascular disease (CVD) in young patients with poorly controlled type 2 diabetes.
  
  
  METHODS
  Fifty-seven Latin American patients with type 2 diabetes, between the ages 18 and 45 years, were screened to participate in a clinical research study evaluating the effects of intensive insulin therapy on both traditional and nontraditional CVD risk factors. All women were premenopausal and had regular menstrual periods. Baseline reviews of cardiovascular (CV) risk scores, personal history, physical examination, and laboratory screening were performed. The Framingham Study Score system and the presence of features of the metabolic syndrome (MSyn) were recorded and compared.
  
  
  RESULTS
  Both genders had a comparable number of features of the MSyn, whereas according to the Framingham Score System, men had a slightly higher risk of CVD.
  
  
  CONCLUSIONS
  The Framingham Score system is not an accurate device to estimate risk of CVD in premenopausal women with type 2 diabetes mellitus, who otherwise have a multiple features of the MSyn. If used to estimate risk of CVD, the Framingham score system could underestimate the risk of CVD in both young men and women with type 2 diabetes mellitus.
authors.affiliation: Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, TX 75390-8858, USA. maines.aviles-santa@utsouthwestern.edu
authors.forename: Larissa
authors.initials: L
authors.lastname: Avilés-Santa
authors.forename: Karin
authors.initials: K
authors.lastname: Salinas
authors.forename: Beverley
authors.initials: B
authors.lastname: Adams-Huet
authors.forename: Philip
authors.initials: P
authors.lastname: Raskin
mesh_terms: D000293:Adolescent; D000328:Adult; D001837:Body Weights and Measures; D002318:Cardiovascular Diseases / Q000208:ethnology* / Q000209:etiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000208:ethnology*; D005260:Female; D006442:Glycated Hemoglobin; D006305:Health Status Indicators; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000208:ethnology; D008875:Middle Aged; D009765:Obesity; D017697:Premenopause; D018570:Risk Assessment / Q000379:methods / Q000592:standards; D012737:Sex Factors; D013781:Texas / Q000453:epidemiology
chemical_list: D006442:Glycated Hemoglobin