Syntheses of new peptidic glycoclusters derived from beta-alanine: di- and trimerized glycoclusters and glycocluster-clusters.
Fluorescence-labeled glycoclusters 1 and 2 have been synthesized to elongate glycocluster units that contain beta-alanine derivative 6 and sugar unit 7. Similarly, di- and trimerized glycoclusters 3 and 4 have been obtained by coupling glycocluster 17 with succinyl chloride and/or trimesoyl chloride, respectively. Furthermore, glycocluster-cluster 5 was also synthesized by a convergent growth approach.
Sato
Koji
K
Kyoritsu University of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.
Hada
Noriyasu
N
Takeda
Tadahiro
T
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002241:Carbohydrates / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry; D019281:Dimerization; D006020:Glycopeptides / Q000138:chemical synthesis*; D019906:Nuclear Magnetic Resonance, Biomolecular; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014233:Tricarboxylic Acids / Q000737:chemistry; D015091:beta-Alanine / Q000737:chemistry*
D002241:Carbohydrates; D002264:Carboxylic Acids; D050091:Dendrimers; D006020:Glycopeptides; D014233:Tricarboxylic Acids; D015091:beta-Alanine