title: Three anti-tumor saponins from Albizia julibrissin.
abstract: Three new triterpenoid saponins, julibroside J(29) (1), julibroside J(30) (2), and julibroside J(31) (3), were isolated from the stem bark of Albizia julibrissin Durazz. (Leguminosae) by using chromatographic method. Their structures were established by spectroscopic methods. Compounds 1, 2, and 3 displayed significant anti-tumor activities in vitro against PC-3M-1E8, HeLa, and MDA-MB-435 cancer cell lines at 10microM assayed by SRB and MTT methods.
authors.affiliation: School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, People's Republic of China.
authors.forename: Lu
authors.initials: L
authors.lastname: Zheng
authors.forename: Jian
authors.initials: J
authors.lastname: Zheng
authors.forename: Yuying
authors.initials: Y
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Lijun
authors.initials: L
authors.lastname: Wu
authors.forename: Hong
authors.initials: H
authors.lastname: Liang
mesh_terms: D031289:Albizzia / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins