title: Hypereosinophilic syndrome accompanying gangrene of the toes with peripheral arterial occlusion--a case report.
abstract: The authors herein report the case of a teenage boy who presented with peripheral arterial occlusion of both upper and lower extremities associated with hypereosinophilia. During a 10-year follow-up, corticosteroid therapy was continued for the treatment of hypereosinophilia. The patient underwent bilateral lumbar sympathectomies because of severe ischemia of the bilateral lower extremities with gangrene of the toes. Based on the progress of his disease over the past 10 years, he was suspected to have idiopathic hypereosinophilic syndrome (HES) accompanied by peripheral arterial obstruction. Idiopathic HES is a disease characterized by unexpected hypereosinophilia, which may lead to organ damage. This is a very rare case of peripheral arterial occlusion associated with idiopathic HIS.
authors.affiliation: Department of Surgery, Section of Vascular Surgery, Saiseikai Yahata General Hospital, Kitakyushu, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Funahashi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Masaki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Furuyama
mesh_terms: D000671:Amputation, Surgical; D001157:Arterial Occlusive Diseases / Q000150:complications* / Q000601:surgery; D002648:Child; D005500:Follow-Up Studies; D005734:Gangrene / Q000150:complications*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D008160:Lumbosacral Plexus / Q000601:surgery; D008297:Male; D011150:Popliteal Artery; D012189:Retrospective Studies; D013562:Sympathectomy; D014034:Toes / Q000473:pathology* / Q000601:surgery