title: An alkoxide-directed carbometalation of internal alkynes.
abstract: A mild and efficient alkoxide-directed carbometalation is described. Regioselective carbon-carbon bond formation occurs in all cases at the site distal to the tethered alkoxide. This reaction provides a convenient means to prepare differentially functionalized tetrasubstituted 1,3-dienes in a regio- and stereoselective manner.
authors.affiliation: Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, CT 06520-8107, USA.
authors.forename: Jamie
authors.initials: J
authors.lastname: Ryan
authors.forename: Glenn C
authors.initials: GC
authors.lastname: Micalizio