Synthesis of 2,3-disubstituted benzo[b]selenophenes via electrophilic cyclization.
2,3-Disubstituted benzo[b]selenophenes have been prepared by the electrophilic cyclization of various 1-(1-alkynyl)-2-(methylseleno)arenes by Br2, NBS, I2, ICl, PhSeCl, PhSeBr, and Hg(OAc)2. This method tolerates a wide variety of functional groups, including alcohol, ester, nitrile, nitro, and silyl groups, and proceeds under exceptionally mild reaction conditions.
Kesharwani
Tanay
T
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Worlikar
Shilpa A
SA
Larock
Richard C
RC
D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012680:Sensitivity and Specificity
D016566:Organoselenium Compounds