title: [The positivity of specific IgE to salmon roe and cod roe in outpatients].
abstract: OBJECTIVE
  To clarify the positivity of specific IgE to salmon and cod roe in outpatients.
  
  
  METHODS
  Specific IgE were assayed using CAP RAST system in 91 pediatric outpatients. They were 47 males and 44 females, including 22 allergic, 29 infectious, 10 neurological, 8 gastrointestinal, 7 urological, 6 hematologic, 3 metabolic disease and 6 other disorders. For control, 30 sera from healthy normal adult volunteers were assayed. Additionally, sera from 653 allergic patients were also collected in our laboratory. Specific IgEs against salmon and cod meat were also assayed simultaneously.
  
  
  RESULTS
  In 91 pediatric patients, two children were salmon roe positive and one child was cod roe positive. Three children scored class 1, borderline positive in salmon roe, and one child scored class 1 in cod roe. Other children were negative in all allergens. No positive sera were found in normal adult volunteers. Among 653 specimens in our laboratory, the positivity of specific IgE to salmon and cod roe were 25%, and 9%, respectively. Infants younger than two years old had higher ratio than older children. There was a significant correlation (r = 0.676) between the titers of IgE to salmon and cod roe. On the other hand, the titers of IgE to their meats correlated less than those to their roes. Our results support previous reports that fish roe from different species have common antigen apart from those of fish meat.
  
  
  CONCLUSIONS
  Positive ratio of salmon and cod roe specific IgE were 2.2 and 1.1% in pediatric outpatients.
authors.affiliation: Department of Clinical Pathology, Showa University School of Medicine, Shinagawa-ku, Tokyo 142-8666.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Shinoda
authors.forename: Takayosi
authors.initials: T
authors.lastname: Kyouda
authors.forename: Akiko
authors.initials: A
authors.lastname: Tomita
authors.forename: Zenji
authors.initials: Z
authors.lastname: Nonaka
authors.forename: Kyoji
authors.initials: K
authors.lastname: Soga
authors.forename: Yoh
authors.initials: Y
authors.lastname: Umeda
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takagi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kimura
mesh_terms: D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004531:Eggs; D005260:Female; D048388:Gadiformes / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007223:Infant; D008297:Male; D010045:Outpatients; D011852:Radioallergosorbent Test; D012474:Salmon / Q000276:immunology*
chemical_list: D007073:Immunoglobulin E