title: Ultra sensitive trace gas detection for biomedical applications.
abstract: We present an overview of our recent progress on spectroscopic trace gas detection for biomedical applications. The latest developments of cavity-enhanced spectroscopy as well as magnetic rotation spectroscopy lead to unprecedented sensitivity and specificity. The current detection limits of our laser spectroscopic approaches are in the picomolar to nanomolar range, depending on the molecular compound. The time resolution of the measurements is down to the sub-second range. This very high sensitivity and time resolution open up exciting perspectives for novel analytical tasks in biomedical research and clinical diagnosis.
authors.affiliation: University of Düsseldorf, Institute for Lasermedizin Medicine, Universitätstr.1, D-40225 Düsseldorf, Germany. muertz@uni-duesselsorf.de
authors.forename: Manfred
authors.initials: M
authors.lastname: Mürtz
authors.forename: Daniel
authors.initials: D
authors.lastname: Halmer
authors.forename: Markus
authors.initials: M
authors.lastname: Horstjann
authors.forename: Sven
authors.initials: S
authors.lastname: Thelen
authors.forename: Peter
authors.initials: P
authors.lastname: Hering
mesh_terms: D035843:Biomedical Research; D005336:Fiber Optic Technology; D005609:Free Radicals / Q000378:metabolism; D005740:Gases / Q000032:analysis*; D006801:Humans; D007834:Lasers; D009569:Nitric Oxide / Q000378:metabolism; D012680:Sensitivity and Specificity
chemical_list: D005609:Free Radicals; D005740:Gases; D009569:Nitric Oxide