title: Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure.
abstract: Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems. Failure of antimonials or severe toxicity is particularly troublesome in patients with renal insufficiency. We report a case of visceral leishmaniaisis and renal insufficiency successfully treated with fluconazole and allopurinol for 4 months.
authors.affiliation: Department of Nephrology, School of Medicine, Pamukkale University, Denizli, Turkey. murcol@mynet.com
authors.forename: Murat
authors.initials: M
authors.lastname: Colakoglu
authors.forename: Guzin
authors.initials: G
authors.lastname: Fidan Yaylali
authors.forename: Nagihan
authors.initials: N
authors.lastname: Yalcin Colakoglu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yilmaz
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use*; D000818:Animals; D000963:Antimetabolites / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D003928:Diabetic Nephropathies / Q000150:complications; D004359:Drug Therapy, Combination; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000963:Antimetabolites; D000981:Antiprotozoal Agents; D000493:Allopurinol; D015725:Fluconazole