title: Emerging drugs for the treatment of sepsis.
abstract: Septic shock still places a major burden on the healthcare system, although recent years have been marked by the demonstration that corticosteroids and activated protein C may substantially improve survival in selected populations. This review discusses the current management of septic shock and the potential development of new therapeutics following impressive advances in the pathomechanisms of septic shock.
authors.affiliation: Intensive Care Unit, University of Versailles Saint Quentin, Hospital Raymond Poincaré, 104 bd Raymond Poincaré, 92380 Garches, France.
authors.forename: Jérome
authors.initials: J
authors.lastname: Aboab
authors.forename: Olivier
authors.initials: O
authors.lastname: Nardi
authors.forename: Diane
authors.initials: D
authors.lastname: Lipiner
authors.forename: Tarek
authors.initials: T
authors.lastname: Sharshar
authors.forename: Djillali
authors.initials: D
authors.lastname: Annane
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000925:Anticoagulants / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008074:Lipoproteins / Q000627:therapeutic use; D011486:Protein C / Q000627:therapeutic use; D012772:Shock, Septic / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D008074:Lipoproteins; D011486:Protein C; C051928:lipoprotein-associated coagulation inhibitor; D006854:Hydrocortisone