The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis.
Sixty-three patients with erythrocytosis exhibiting a range of erythropoietin levels were screened for the JAK2 V617F mutation. One patient (1.6%) was found to have this mutation, and has remained stable for 9 years, suggesting that the JAK2 V617F mutation is rare in patients with idiopathic erythrocytosis.
Percy
Melanie J
MJ
Jones
Frank G C
FG
Green
Anthony R
AR
Reilly
John T
JT
McMullin
Mary Frances
MF
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D053614:Janus Kinase 2; D008875:Middle Aged; D009154:Mutation; D010649:Phenylalanine / Q000235:genetics; D011086:Polycythemia / Q000201:enzymology* / Q000453:epidemiology / Q000235:genetics*; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D014633:Valine / Q000235:genetics
D011518:Proto-Oncogene Proteins; D010649:Phenylalanine; D011505:Protein-Tyrosine Kinases; C507924:JAK2 protein, human; D053614:Janus Kinase 2; D014633:Valine