title: Study of electrolyte induced aggregation of gold nanoparticles capped by amino acids.
abstract: This work reports the electrolyte induced aggregation of gold nanoparticles directly conjugated to amino acid by chemical reduction in aqueous solution. The study was focused on three different classes of amino acids depending on the nature of alpha substituent, viz. l-cysteine, l-leucine, and l-asparagine. The band broadening and the red shift of surface plasmon band with increase in flocculation parameter showed the aggregation of gold nanoparticles with increase in electrolyte concentration and decrease in pH as monitored by UV-visible spectrophotometer. The (1)H NMR spectrum demonstrates that the sulfide bond of cysteine and alpha amino group of leucine and asparagine interact with nanoparticles surface. Furthermore, transmission electron microscope (TEM) and thermogravimetric analysis (TGA) were performed to characterize and to support the fate of stabilization of the gold nanoparticles by amino acid.
authors.affiliation: Department of Bionanosystem Engineering, Chonbuk National University, Chonju 561-756, Republic of Korea.
authors.forename: Santosh
authors.initials: S
authors.lastname: Aryal
authors.forename: Bahadur K C
authors.initials: BK
authors.lastname: Remant
authors.forename: Bhattarai
authors.initials: B
authors.lastname: Narayan
authors.forename: Chul Ki
authors.initials: CK
authors.lastname: Kim
authors.forename: Hak Yong
authors.initials: HY
authors.lastname: Kim
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D010084:Oxidation-Reduction; D013056:Spectrophotometry, Ultraviolet; D013440:Sulfides / Q000737:chemistry*; D020349:Surface Plasmon Resonance
chemical_list: D000596:Amino Acids; D004573:Electrolytes; D013440:Sulfides; D006046:Gold