Isolation of yessotoxin 32-O-[beta-L-arabinofuranosyl-(5'-->1'')-beta-L-arabinofuranoside] from Protoceratium reticulatum.
Yessotoxin 32-O-[beta-L-arabinofuranosyl-(5'-->1'')-beta-L-arabinofuranoside] (3) was isolated from extracts of Protoceratium reticulatum during a large scale isolation of yessotoxin (1). The structure was characterized by mass spectrometry and NMR spectroscopy. Di-glycoside-3, along with the corresponding mono-glycoside (2) were detected in cultures of P. reticulatum originating from Europe and New Zealand, suggesting that production of arabinosides of 1 is a normal feature of this alga. Formation of multiply charged anions and fragmentation of 3 occurred much more readily than for 1 and 2 under the LC-MS conditions used in this study.
Miles
Christopher O
CO
Department of Toxinology, AgResearch Ltd, Ruakura Research Centre, PB 3123, East Street, Hamilton, New Zealand. chris.miles@agresearch.co.nz
Wilkins
Alistair L
AL
Selwood
Andrew I
AI
Hawkes
Allan D
AD
Jensen
Dwayne J
DJ
Cooney
Janine M
JM
Beuzenberg
Veronica
V
MacKenzie
A Lincoln
AL
D000818:Animals; D008958:Models, Molecular; D015394:Molecular Structure; D008978:Mollusk Venoms / Q000737:chemistry* / Q000302:isolation & purification*; D035964:Oxocins / Q000737:chemistry / Q000302:isolation & purification*
D008978:Mollusk Venoms; D035964:Oxocins; C510944:yessotoxin 32-O-(beta-L-arabinofuranosyl-(5'-1'')-beta-L-arabinofuranoside), Protoceratium reticulatum