title: Advanced immunosuppression at entry to HIV care in the southeastern United States and associated risk factors.
abstract: In this study we characterized factors associated with the late initiation of HIV care in the southeastern United States. At initiation of care, antiretroviral therapy was indicated for 75% of patients, 50% had a CD4 cell count of less than 200 cells/mul, and 27% presented with an AIDS-defining illness. Male sex was an independent predictor in multivariable analysis. These results indicate an urgent need to increase HIV testing for earlier diagnosis in the southeastern USA.
authors.affiliation: The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Gay
authors.forename: Sonia
authors.initials: S
authors.lastname: Napravnik
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Eron
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D015497:HIV-1 / Q000235:genetics; D006801:Humans; D007165:Immunosuppression Therapy; D016015:Logistic Models; D008297:Male; D009657:North Carolina; D018579:Patient Selection; D012367:RNA, Viral / Q000097:blood; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors
chemical_list: D044966:Anti-Retroviral Agents; D012367:RNA, Viral