Aristolochic acid-related nephropathy associated with the popular Chinese herb Xi Xin.
Chinese herbs nephropathy is known as a subacute interstitial nephritis attributed to aristolochic acid. This work describes the case of a 49-year-old male who displayed subacute renal failure induced by ingestion of herbal powder containing Xi Xin, which includes aristolochic acid. Since Xi Xin is a common ingredient in traditional formulae, care needs to be taken in the future to identify the aristolochic acid concentration of different components of Xi Xin. Xi Xin containing aristolochic acid should be forbidden for use in remedies in order to prevent the harmful effects of aristolochic acid.
Yang
Huang-Yu
HY
Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Lin
J-L
JL
Chen
Kuan-Hsing
KH
Yu
Chun-Chen
CC
Hsu
Po-Yaur
PY
Lin
Chun-Liang
CL
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000473:pathology; D034341:Aristolochic Acids / Q000009:adverse effects*; D001706:Biopsy; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged
D034341:Aristolochic Acids; D004365:Drugs, Chinese Herbal; C000228:aristolochic acid I