title: [A case report of autoimmune pancreatitis with Mikulicz' s disease and diabetes mellitus].
abstract: A 56-year-old man with bilateral swelling of lacrimal glands was admitted to our hospital. He was diagnosed as autoimmune pancreatitis with Mikulicz' s disease presenting the swelling of lacrimal glands, submandibular glands and the pancreas head and tail. Treatment with systemic prednisolone resulted in improvement of the swelling of these glands and pancreas. On the immunohistochemical examination, infiltration of CD4- and CD8-positive T lymphocytes was detected in the lacrimal gland, the submandibular gland, the gall bladder and the pancreas. Infiltration of IgG4-positive plasma cells was detected in the submandibular gland, the gall bladder and the pancreas. These results may suggest the presence of common etiology between autoimmune pancreatitis and Mikulicz' s disease.
authors.affiliation: The First Department of Internal Medicine, Wakayama Medical University.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Takagi
authors.forename: Takuya
authors.initials: T
authors.lastname: Doi
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Hitomi
authors.initials: H
authors.lastname: Tatsuta
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Yukari
authors.initials: Y
authors.lastname: Tsubota
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nishino
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Nakano
authors.forename: Hisao
authors.initials: H
authors.lastname: Wakasaki
authors.forename: Hiroto
authors.initials: H
authors.lastname: Furuta
authors.forename: Kishio
authors.initials: K
authors.lastname: Nanjo
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications*; D048909:Diabetes Complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D008882:Mikulicz' Disease / Q000150:complications*; D010195:Pancreatitis / Q000150:complications*