title: [Antimycobacterial activity of a dry birch bark extract on a model of experimental pulmonary tuberculosis].
abstract: The study deals with the evaluation of antimycobacterial activity of betulinol, a dry birch bark extract (BBE), on a model of infection caused by Mycobacterium tuberculosis (MBT). It has established the inhibitory action of betulinol on the in vitro and in vivo growth of MBT and its positive effect on reparative processes in the lung, liver, and spleen of tuberculosis-infected mice.
authors.forename: O V
authors.initials: OV
authors.lastname: Demikhova
authors.forename: V V
authors.initials: VV
authors.lastname: Balakshin
authors.forename: G A
authors.initials: GA
authors.lastname: Presnova
authors.forename: I V
authors.initials: IV
authors.lastname: Bocharova
authors.forename: L N
authors.initials: LN
authors.lastname: Lepekha
authors.forename: L N
authors.initials: LN
authors.lastname: Chernousova
authors.forename: T G
authors.initials: TG
authors.lastname: Smirnova
authors.forename: L E
authors.initials: LE
authors.lastname: Pospelov
authors.forename: A N
authors.initials: AN
authors.lastname: Chistiakov
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D029662:Betula; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D008517:Phytotherapy / Q000379:methods*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents