Determinants of adherence to non-occupational post HIV exposure prophylaxis.
We conducted a study on 140 patients who sought advice at hospital after a non-occupational exposure. The full 28-day course of prophylactic antiretroviral therapy was completed by 109 patients. No HIV contamination was observed. Factors associated with suboptimal adherence were African ethnicity [odds ratio (OR) 13.3, 2.02-87.54] and oral sexual intercourse (OR 8.35, 1.66-41.99). Compliance with prophylactic antiretroviral therapy can be increased by addressing social and psychological barriers to adherence.
Lacombe
Karine
K
Service de Maladies Infectieuses et Tropicales, Paris, France.
Daguenel-Nguyen
Anne
A
Lebeau
Véronique
V
Fonquernie
Laurent
L
Girard
Pierre-Marie
PM
Meyohas
Marie-Caroline
MC
D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active; D044383:Black People / Q000523:psychology; D004334:Drug Administration Schedule; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology / Q000635:transmission; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000208:ethnology / Q000523:psychology*; D012725:Sexual Behavior
D019380:Anti-HIV Agents