title: Painful metal-on-metal total hip arthroplasty.
abstract: Two patients were evaluated for the possibility of hypersensitivity to a Metasul articulation (Centerpulse, Austin, Tex) coupled with total hip arthroplasty. Serum was tested with a lymphocyte proliferation assay, and the capsular tissues from the hip were examined for perivascular lymphocytes. The diagnosis of hypersensitivity to Metasul could not be confirmed in these patients, and ultimately, the painful hip arthroplasties were felt to be caused by a combination of musculoskeletal problems.
authors.affiliation: Dorr Arthritis Institute, Department of Orthopedics, Arthritis Institute at Centinela Hospital Medical Center, Inglewood, CA, USA.
authors.forename: Cambize
authors.initials: C
authors.lastname: Shahrdar
authors.forename: Pat
authors.initials: P
authors.lastname: Campbell
authors.forename: Joseph
authors.initials: J
authors.lastname: Mirra
authors.forename: Lawrence D
authors.initials: LD
authors.lastname: Dorr
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001672:Biocompatible Materials / Q000009:adverse effects; D002857:Chromium / Q000009:adverse effects; D003035:Cobalt / Q000009:adverse effects; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology*; D011474:Prosthesis Design
chemical_list: D001672:Biocompatible Materials; D002857:Chromium; D003035:Cobalt