[Significance of combined cardiovascular pathology in prediction of long-term results of renal transplantation].
Cardiovascular pathology (CVP) is the main cause of death in patients with end-stage chronic renal failure (ESCRF) and recipients of renal allotransplants (RAT). Combined CVP is found in many patients with ESCRF. The aim of the study was to evaluate the influence of pre-existing combined CVP on the length of life of recipients during the functioning of RAT. The results of renal allotransplantation were analyzed in 142 RAT recipients. Statistic processing was performed using tabulation, construction of survival curves, and Kaplan-Meier estimates. The study established the prognostic value of a combination of several CVP in one patient. The total severity of the prognosis for patients and RATs differs depending on the number of concomitant cardiovascular diseases. The presence of three or more CVPs before performing renal allotransplantation is a predictor of lower survivability. The length of RAT functioning is significantly shorter in patients with two or more CVPs before renal allotransplantation. The presence of combined CVP should be taken into account when selecting and preparing patients with ESCRF for renal allotransplantation.
Stoliar
A G
AG
Budkar'
L N
LN
Luzina
N G
NG
Zlokazov
V B
VB
Bugaeva
I V
IV
D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000150:complications* / Q000401:mortality; D002648:Child; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D016019:Survival Analysis; D014184:Transplantation, Homologous; D016896:Treatment Outcome