Relationship between uterine blood flow and endometrial and subendometrial blood flows during stimulated and natural cycles.
OBJECTIVE
To evaluate the relationship between uterine Doppler flow and endometrial and subendometrial blood flows during stimulated and natural cycles.


METHODS
A prospective observational study.


METHODS
A tertiary-assisted reproduction unit.


METHODS
Infertile patients undergoing IVF treatment.


METHODS
A three-dimensional ultrasound examination with power Doppler was performed on the day of egg retrieval in stimulated cycles and the day after the LH surge in natural cycles.


METHODS
Pulsatility and resistance indices of uterine vessels, and the vascularization, flow, and vascularization flow indices of endometrial and subendometrial regions.


RESULTS
Uterine pulsatility and resistance indices were negatively correlated with subendometrial vascularization, flow, and vascularization flow indices in both stimulated and natural cycles, whereas uterine resistance index was negatively correlated with endometrial vascularization and flow indices in natural cycles only. Subendometrial vascularization and vascularization flow indices were significantly lower in patients with an uterine resistance index > or =0.95 than those with an uterine resistance index <0.95.


CONCLUSIONS
Uterine blood flow is a poor reflection of subendometrial blood flow during stimulated and natural cycles, and its measurement cannot reflect endometrial blood flow during stimulated cycles.
Ng
Ernest H Y
EH
Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China. nghye@hkucc.hku.hk
Chan
Carina C W
CC
Tang
Oi S
OS
Yeung
William S B
WS
Ho
Pak C
PC
D000328:Adult; D002064:Buserelin / Q000627:therapeutic use; D004717:Endometrium / Q000098:blood supply* / Q000000981:diagnostic imaging; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology* / Q000628:therapy; D008597:Menstrual Cycle; D010062:Ovulation Induction; D011446:Prospective Studies; D011674:Pulse; D012039:Regional Blood Flow; D018615:Ultrasonography, Doppler, Color; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging; D014655:Vascular Resistance
D005300:Fertility Agents, Female; D002064:Buserelin