title: The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis.
abstract: Sixty-three patients with erythrocytosis exhibiting a range of erythropoietin levels were screened for the JAK2 V617F mutation. One patient (1.6%) was found to have this mutation, and has remained stable for 9 years, suggesting that the JAK2 V617F mutation is rare in patients with idiopathic erythrocytosis.
authors.forename: Melanie J
authors.initials: MJ
authors.lastname: Percy
authors.forename: Frank G C
authors.initials: FG
authors.lastname: Jones
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Green
authors.forename: John T
authors.initials: JT
authors.lastname: Reilly
authors.forename: Mary Frances
authors.initials: MF
authors.lastname: McMullin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D053614:Janus Kinase 2; D008875:Middle Aged; D009154:Mutation; D010649:Phenylalanine / Q000235:genetics; D011086:Polycythemia / Q000201:enzymology* / Q000453:epidemiology / Q000235:genetics*; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D014633:Valine / Q000235:genetics
chemical_list: D011518:Proto-Oncogene Proteins; D010649:Phenylalanine; D011505:Protein-Tyrosine Kinases; C507924:JAK2 protein, human; D053614:Janus Kinase 2; D014633:Valine