[Particular features of the impact of certain vegetotropic drugs on the excitability of cholinergic structures, contractile myocardial function and electromotive stomach activity].
The study examined particular features of the impact of propranolol (obsidan), bretylium tosylate (ornid), sumatriptan (imigran) and morphine on the excitability of cholinergic structures, contractile myocardial function and electromotive stomach activity. It was shown that ornid and obsidan reduce the contractile myocardial function, and a drug of selection can be ornid. Introduction of morphine reduced the excitability threshold of myocardial cholinergic structures. Sumatriptan is a 5-HT 1,2-serotonin blocker.
Lychkova
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D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects; D001950:Bretylium Tosylate / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D009020:Morphine / Q000494:pharmacology*; D009043:Motor Activity; D009200:Myocardial Contraction; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects; D044406:Receptors, Serotonin, 5-HT3 / Q000187:drug effects; D013270:Stomach / Q000187:drug effects* / Q000502:physiology; D018170:Sumatriptan / Q000494:pharmacology*
D011950:Receptors, Cholinergic; D044406:Receptors, Serotonin, 5-HT3; D009020:Morphine; D001950:Bretylium Tosylate; D018170:Sumatriptan; D011433:Propranolol