title: Laparoscopic ultrasound-guided radiofrequency ablation of uterine fibroids.
abstract: Four patients with symptomatic uterine fibroids measuring less than 6 cm underwent laparoscopic ultrasound-guided radiofrequency ablation (RFA) using multiprobe-array electrodes. Follow-up of the treated fibroids was performed with gadolinium-enhanced magnetic resonance imaging (MRI) and patients' symptoms were assessed by telephone interviews. The procedure was initially technically successful in 3 of the 4 patients and MRI studies at 1 month demonstrated complete fibroid ablation. Symptom improvement, including a decrease in menstrual bleeding and pain, was achieved in 2 patients at 3 months. At 7 months, 1 of these 2 patients experienced symptom worsening which correlated with recurrent fibroid on MRI. The third, initially technically successfully treated patient did not experience any symptom relief after the procedure and was ultimately diagnosed with adenomyosis. Our preliminary results suggest that RFA is a technically feasible treatment for symptomatic uterine fibroids in appropriately selected patients.
authors.affiliation: Department of Medical Imaging, University of Toronto, 657 University Avenue, Mulock Larkin Wing, Room 1-042, Toronto, Ontario M5G 2C4, Canada.
authors.forename: Andrea
authors.initials: A
authors.lastname: Milic
authors.forename: Murray R
authors.initials: MR
authors.lastname: Asch
authors.forename: Peter A
authors.initials: PA
authors.lastname: Hawrylyshyn
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Allen
authors.forename: Terence J
authors.initials: TJ
authors.lastname: Colgan
authors.forename: John R
authors.initials: JR
authors.lastname: Kachura
authors.forename: Eran B
authors.initials: EB
authors.lastname: Hayeems
mesh_terms: D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008875:Middle Aged; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*