title: The aer-o-scope: proof of concept of a pneumatic, skill-independent, self-propelling, self-navigating colonoscope.
abstract: OBJECTIVE
  Endoscopic screening of the colon with available instruments requires considerable training, is often painful, and carries a risk of perforation. New instrument platforms for endoscopic screening could be useful. The aim of this study was to evaluate the extent of colonic intubation by using a novel self-propelled, self-navigating endoscope (the Aer-O-Scope; GI View Ltd, Ramat Gan, Israel).
  
  
  METHODS
  Twelve young healthy volunteers underwent complete bowel preparation followed by a nonsedated examination using the novel device. Each examination was followed by a standard colonoscopy for safety evaluation. Cecal intubation was confirmed by endoscopic landmarks and fluoroscopy.
  
  
  RESULTS
  In 10 out of 12 subjects (83%) the cecum was successfully reached, whereas in 2 cases the Aer-O-Scope advanced to the hepatic flexure. The time to complete advancement to cecum averaged 14.0 +/- 7 minutes, and the driving pressures averaged 34 +/- 2.3 milibar. Two subjects requested analgesics during the procedures (in both cases the cecum was reached). Four subjects experienced sweating and a bloating sensation that resolved spontaneously. All subjects were followed up to 48 hours and then for 30 days postprocedure, and no complications were observed.
  
  
  CONCLUSIONS
  In a preliminary pilot feasibility study of this new instrument, the Aer-O-Scope effectively intubated all or most of the colon. Further clinical studies are warranted.
authors.affiliation: Rebro University Hospital, Zagreb, Croatia.
authors.forename: Boris
authors.initials: B
authors.lastname: Vucelic
authors.forename: Douglas
authors.initials: D
authors.lastname: Rex
authors.forename: Roland
authors.initials: R
authors.lastname: Pulanic
authors.forename: Jorge
authors.initials: J
authors.lastname: Pfefer
authors.forename: Irena
authors.initials: I
authors.lastname: Hrstic
authors.forename: Bernard
authors.initials: B
authors.lastname: Levin
authors.forename: Zamir
authors.initials: Z
authors.lastname: Halpern
authors.forename: Nadir
authors.initials: N
authors.lastname: Arber
mesh_terms: D000328:Adult; D020685:Colonoscopes; D005260:Female; D006801:Humans; D008297:Male; D012449:Safety