title: Spontaneous splenic rupture, in tertian malaria.
abstract: We report a case of tertian malaria in a 36-year-old Caucasian male complicated by spontaneous splenic rupture 2 months after returning from Kenya. The ruptured and enlarged spleen displaying multiple subcapsular hemorrhages was surgically resected. Histological examination revealed a marked enlargement of the red pulp and a reduced white pulp in addition to hyperemia of the spleen. Tertian malaria was diagnosed by peripheral blood smear and elevated antibody titer against Plasmodium vivax. The patient underwent antimalarial therapy with chloroquine and primaquine and the further course was uneventful. Etiopathology, differential diagnosis and therapy of this rare complication in malaria are discussed.
authors.affiliation: Dept. of General and Abdominal Surgery, University of Mainz, Langenbeckstr. 1, 55101 Mainz, Germany.
authors.forename: H R
authors.initials: HR
authors.lastname: Gockel
authors.forename: J
authors.initials: J
authors.lastname: Heidemann
authors.forename: D
authors.initials: D
authors.lastname: Lorenz
authors.forename: I
authors.initials: I
authors.lastname: Gockel
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D006801:Humans; D016780:Malaria, Vivax / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology; D008297:Male; D010966:Plasmodium vivax / Q000302:isolation & purification; D012422:Rupture, Spontaneous / Q000209:etiology* / Q000469:parasitology; D013161:Splenic Rupture / Q000209:etiology* / Q000469:parasitology
chemical_list: D000962:Antimalarials