Configurational analysis of cubebins and bicubebin from Aristolochia lagesiana and Aristolochia pubescens.
(8S,8'R,9S)-, (8R,8'R,9R)-, and (8R,8'R,9S)-cubebins, together with (8R,8'R,8''R,8'''R,9R,9''S)-bicubebin, were isolated from Aristolochia lagesiana and Aristolochia pubescens. Their structures were determined by spectroscopic methods, including 1H and 13C NMR spectroscopy at low temperatures, and by chemical transformations.
de Pascoli
Inara C
IC
Instituto de Química, Universidade Estadual Paulista, UNESP, C.P. 355, 14801-970, Araraquara, São Paulo, Brazil.
Nascimento
Isabele R
IR
Lopes
Lucia M X
LM
D015107:4-Butyrolactone / Q000737:chemistry / Q000494:pharmacology; D030022:Aristolochia / Q000737:chemistry*; D002942:Circular Dichroism; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry*; D010946:Plants, Medicinal
D017705:Lignans; D010936:Plant Extracts; C433065:cubebin; D015107:4-Butyrolactone