title: A case report of primary osteosarcoma of the ovary.
abstract: Primary osteosarcoma is one of the rare tumors affecting ovaries. This case is being reported for its rarity, along with a review of the literature. In this study, the patient, a 43-year-old woman, presented with an abdominopelvic mass. Exploratory laparotomy was performed, which revealed an extensive left ovarian mass infiltrating the uterus, small bowel, and urinary bladder. Subtotal hysterectomy and small bowel resection followed by end-to-end anastomosis and bilateral salpingo-ophorectomy were performed. Histopathology showed primary osteosarcoma of the ovary. Eighteen days after surgery, she started presenting with progressive abdominal distention and ultimately developed subacute intestinal obstruction. She was started on carboplatin and epirubicin combination but failed to respond and died of fast progressive disease. It is concluded that primary osteosarcoma of the ovary is a rare disease with poor prognosis.
authors.affiliation: Department of Medical Oncology, Kuwait Cancer Control Center, Kuwait City, Kuwait. vinay25vyas@rediffmail.com
authors.forename: V
authors.initials: V
authors.lastname: Vyas
authors.forename: A M A
authors.initials: AM
authors.lastname: Rammah
authors.forename: S D
authors.initials: SD
authors.lastname: Ashebu
authors.forename: G M
authors.initials: GM
authors.lastname: Sharaan
authors.forename: M
authors.initials: M
authors.lastname: El-Sayed
authors.forename: N
authors.initials: N
authors.lastname: Jarslov
authors.forename: A
authors.initials: A
authors.lastname: El-Khodary
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D015251:Epirubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007414:Intestinal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D007421:Intestine, Small; D009361:Neoplasm Invasiveness; D012516:Osteosarcoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D016179:Granulocyte Colony-Stimulating Factor; D015251:Epirubicin; D016190:Carboplatin