title: Synthesis of substituted 2-cyanoarylboronic esters.
abstract: The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.
authors.affiliation: Department of Medicinal Chemistry, Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
authors.forename: Morten
authors.initials: M
authors.lastname: Lysén
authors.forename: Henriette M
authors.initials: HM
authors.lastname: Hansen
authors.forename: Mikael
authors.initials: M
authors.lastname: Begtrup
authors.forename: Jesper L
authors.initials: JL
authors.lastname: Kristensen
mesh_terms: D001897:Boronic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids