title: Microencapsulated BioBullets for the control of biofouling zebra mussels.
abstract: The widespread invasion of freshwaters by the zebra mussel, Dreissena polymorpha, during the last 2 decades has made it one of the world's most economically and ecologically important pests. Since arriving in the North American Great Lakes in the 1980s, zebra mussels have become a major biofouler, blocking the raw water cooling systems of power stations and water treatment works and costing U.S. dollars 1-5 billion per year. Despite the development of numerous control methods, chlorination remains the only widespread and licensed technique. Zebra mussels are able to sense chlorine and othertoxins in their surrounding environment and respond by closing their valves, thus enabling them to avoid toxic effects for up to 3 weeks. Furthermore, prolonged dosing of chlorine in raw water produces ecotoxic trihalomethanes (THMs) by reaction with organic material in the water. We have developed a novel, environmentally safe, and effective method for controlling the zebra mussel: the BioBullet. Our method uses the encapsulation of an active ingredient (KCI) in microscopic particles of edible material. The mussels' natural filtering ability then removes and concentrates the particles from the water, without stimulating the valve-closing response. By using the mussels' filtering behavior to concentrate BioBullets the absolute quantity of active ingredient added to the water can be reduced substantially. Our approach allows us to engineer the particles to break up and dissolve completely within a few hours, thus eliminating the risk of polluting the wider ecosystem. We demonstrate that the effectiveness of a toxin in the control of biofouling filter-feeders can be enhanced greatly by using our technique. This paves the way for a new approach to the control of some of the world's most important economic pests.
authors.affiliation: Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. d.aldridge@zoo.cam.ac.uk
authors.forename: David C
authors.initials: DC
authors.lastname: Aldridge
authors.forename: Paul
authors.initials: P
authors.lastname: Elliott
authors.forename: Geoff D
authors.initials: GD
authors.lastname: Moggridge
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000254:growth & development*; D004339:Drug Compounding; D004738:Engineering; D005247:Feeding Behavior; D005374:Filtration; D049329:Nanostructures; D010571:Pest Control / Q000379:methods*; D011189:Potassium Chloride / Q000008:administration & dosage* / Q000633:toxicity*; D011210:Power Plants; D012995:Solubility; D018508:Water Purification
chemical_list: D011189:Potassium Chloride