Endothelial function and the prediction of CVD in diabetes.
Endothelial dysfunction has received increasing attention as a potential contributor to the pathogenesis of vascular disease in diabetes mellitus. Technologies to detect endothelial dysfunction include assessment of endothelium-dependent vasodilatation and plasma levels of cell injury markers. Although clinical and epidemiologic studies show associations and potential links between endothelial dysfunction and outcome in diabetes, there is a substantial need for further work.
Bugiardini
Raffaelle
R
Department of Internal Medicine, Cardio-Angiology and Hepatology, Padiglione 11, University of Bologna, Via Massarenti 9, Bologna 40138, Italy. raffaele.bugiardini@unibo.it
D050197:Atherosclerosis / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000503:physiopathology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000453:epidemiology* / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D006801:Humans; D011237:Predictive Value of Tests; D018570:Risk Assessment