title: An appropriate indicator for diagnosing gestational diabetes.
abstract: BACKGROUND
  This study was intended to simplify the diagnostic procedure for gestational diabetes mellitus (GDM) through using a single plasma glucose level, after a 100 g oral glucose tolerance test (OGTT), as the most appropriate indicator for diagnosing GDM in pregnant women with a positive 50 g, 1-hour oral glucose challenge test (GCT) in Northern Taiwan.
  
  
  METHODS
  A total of 973 native Taipei metropolitan pregnant women with a positive GCT, who underwent a 100 g, 3-hour OGTT were retrospectively surveyed. GDM was defined according to the standards of National Diabetes Data Group. Plasma glucose levels, obtained 1 hour following a GCT and at multiple timing following a 100 g oral glucose load, were used to plot receiver operative characteristic curves to determine the most appropriate indicator for diagnosing GDM.
  
  
  RESULTS
  In the 973 pregnant women with a positive GCT, a 2-hour plasma glucose level above 165 mg/dl revealed a sensitivity and specificity of 91.2% and 90.3%, respectively.
  
  
  CONCLUSIONS
  To simplify the diagnostic procedure for GDM, we suggest that a 2-hour plasma glucose level above 165 mg/dl after a 100 g OGTT might be an appropriate indicator for diagnosing GDM in women with a positive GCT.
authors.affiliation: Division of Endocrinology & Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei.
authors.forename: Jui-Hung
authors.initials: JH
authors.lastname: Sun
authors.forename: Lai-Chu
authors.initials: LC
authors.lastname: See
authors.forename: Tsung-Hong
authors.initials: TH
authors.lastname: Chiu
authors.forename: T'sang-T'ang
authors.initials: TT
authors.lastname: Hsieh
authors.forename: Miau-Ju
authors.initials: MJ
authors.lastname: Huang
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D016640:Diabetes, Gestational / Q000175:diagnosis*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D012372:ROC Curve; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose