title: [Randomized clinical trial: effectiveness of the cognitive-behavioral approach and the use of nicotine replacement transdermal patches for smoking cessation among adults in Rio de Janeiro, Brazil].
abstract: Randomized clinical trial carried out to investigate the effectiveness of the cognitive-behavioral approach and nicotine replacement therapy with nicotine patches for smoking cessation. Participated 1,199 adults, volunteers, in Rio de Janeiro, Brazil, randomly assigned to 10 different groups: intensive brief counseling group (GB), with 1 or 2 sessions (G1-G2), and with 3 or 4 sessions (G3-G4), with/without nicotine replacement therapy (NRT). Abstinence proportions were estimated during 12 months. These proportions among participants not assigned to NRT were 20% (GB), 17% (G1-G2), and 23% (G3-G4); and among assigned NRT groups were 30% (GBA), 34% (G1A-G2A), and 33% (G3A-G4A). After multiple adjustments, the abstinence proportions ratios seemed to follow a "dose-response" pattern: compared to GB, the ratios were 0.85 (G1-G2), 1.13 (G3-G4), 1.51 (GBA), 1.66 (G1A-G2A), and 1.75 (G3A-G4A). The results suggest that use of NRT increases the abstinence proportion for cessation. The "dose-response" pattern suggests that cognitive-behavioral could be the reasonable option in the smoking cessation therapy.
authors.affiliation: Coordenação de Prevenção e Vigilância, Instituto Nacional de Câncer, Rua dos Inválidos 212, 2o andar, Rio de Janeiro, RJ 20231-020, Brazil. uotero@inca.gov.br
authors.forename: Ubirani Barros
authors.initials: UB
authors.lastname: Otero
authors.forename: Cristina de Abreu
authors.initials: Cde A
authors.lastname: Perez
authors.forename: Moysés
authors.initials: M
authors.lastname: Szklo
authors.forename: Gilcenira Ataliba
authors.initials: GA
authors.lastname: Esteves
authors.forename: Mariana Marques
authors.initials: MM
authors.lastname: dePinho
authors.forename: André Salem
authors.initials: AS
authors.lastname: Szklo
authors.forename: Silvana Rubano B
authors.initials: SR
authors.lastname: Turci
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D015992:Body Mass Index; D015928:Cognitive Behavioral Therapy; D003376:Counseling; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage*; D018722:Nicotinic Agonists / Q000008:administration & dosage*; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D000074606:Smoking Prevention; D012959:Socioeconomic Factors; D014029:Tobacco Use Disorder / Q000628:therapy*
chemical_list: D018722:Nicotinic Agonists; D009538:Nicotine