title: Flavan-4-ol Glycosides from the Rhizomes of Abacopteris penangiana.
abstract: Four new flavan-4-ol glycosides, abacopterins A-D (1-4), were isolated from a methanol extract of the rhizomes of Abacopteris penangiana, together with two known compounds, triphyllin A (5) and 6,8-dimethyl-7-hydroxy-4'-methoxyanthocyanidin-5-O-beta-D-glucopyranoside (6). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. The cytotoxic activity of 1-5 against HepG2 human hepatoma cells was investigated.
authors.affiliation: College of Pharmacy, Tongji Medical Center, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China.
authors.forename: Zhongxiang
authors.initials: Z
authors.lastname: Zhao
authors.forename: Jinlan
authors.initials: J
authors.lastname: Ruan
authors.forename: Jing
authors.initials: J
authors.lastname: Jin
authors.forename: Jian
authors.initials: J
authors.lastname: Zou
authors.forename: Daonian
authors.initials: D
authors.lastname: Zhou
authors.forename: Wei
authors.initials: W
authors.lastname: Fang
authors.forename: Fanbo
authors.initials: F
authors.lastname: Zeng
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D006027:Glycosides; C508823:triphyllin A