title: Walking capacity in mild to moderate Parkinson's disease.
abstract: OBJECTIVE
  To examine walking capacity in people with mild to moderate Parkinson's disease (PD), specifically, to determine whether spatiotemporal abnormalities observed when people with PD walk over short distances are exacerbated over longer distances and whether these and other motor impairments affect walking capacity.
  
  
  METHODS
  Descriptive study comparing participants with PD and healthy participants.
  
  
  METHODS
  University laboratory.
  
  
  METHODS
  Sixteen participants (mean age, 65y) with mild to moderate PD (stages 1-3 of the Hoehn and Yahr rating scale) were tested "on" medication. Twenty-two healthy participants (mean age, 66y) formed a control group.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Walking capacity was quantified as the distance walked in the 6-minute walk test (6MWT), hypokinesia during walking was quantified as "fast-as-possible" velocity over 8m, hypokinesia during turning was quantified as the time taken to complete a 360 degrees turn in standing, automaticity was quantified as velocity during dual-task walking expressed as a percentage of velocity during single-task walking over 8m, and muscle strength was quantified as peak isometric knee extensor torque.
  
  
  RESULTS
  The PD group covered less distance (P=.01) in the 6MWT than the control group. Although both groups recorded similar fast-as-possible walking velocities, the PD group walked at only 76% of their fast-as-possible velocity during the 6MWT compared with 84% for the control group (P=.002). In the PD group, 94% of the variance in walking capacity was accounted for by hypokinesia during walking and turning as well as strength (P<.001).
  
  
  CONCLUSIONS
  Even when people with PD are capable of walking at velocities comparable to healthy controls, they do not sustain this velocity over longer distances. Training that targets high velocities warrants investigation as a remediation technique.
authors.affiliation: School of Physiotherapy, University of Sydney, Lidcombe, NSW, Australia. C.Canning@fhs.usyd.edu.au
authors.forename: Colleen G
authors.initials: CG
authors.lastname: Canning
authors.forename: Louise
authors.initials: L
authors.lastname: Ada
authors.forename: Justin J
authors.initials: JJ
authors.lastname: Johnson
authors.forename: Stephanie
authors.initials: S
authors.lastname: McWhirter
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D005684:Gait / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000502:physiology; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D012720:Severity of Illness Index; D013028:Space Perception / Q000502:physiology*; D013998:Time Perception / Q000502:physiology*; D016138:Walking / Q000502:physiology*