title: Treatment results of patients with a squamous cell carcinoma of the buccal mucosa.
abstract: The purpose of this study was to evaluate outcome and value of follow-up of squamous cell carcinoma (SCC) of the buccal mucosa in patients treated at the Radboud University Nijmegen Medical Centre, The Netherlands. A longitudinal cohort study was performed involving 32 patients treated with curative intent (surgery on indication followed by radiotherapy) for SCC of the buccal mucosa from 1987 to 2002, with a minimum follow-up of three years. The prognosis of SCC of the buccal mucosa is comparable to other sites of the oral cavity. The success rate of therapy for a local and/or regional recurrence is very limited. Patients with a second primary tumour (SPT) can be cured if the tumour is detected in an early stage. Routine follow-up used to detect local recurrence or SPT has almost no value after five years and seems of limited value after three years.
authors.affiliation: Radboud University Nijmegen Medical Centre, Department of Oral and Maxillofacial Surgery, 590, P.O. Box 9101, NL 6500, HB Nijmegen, Netherlands.
authors.forename: Casper
authors.initials: C
authors.lastname: Coppen
authors.forename: Peter C M
authors.initials: PC
authors.lastname: de Wilde
authors.forename: Lucas A
authors.initials: LA
authors.lastname: Pop
authors.forename: Franciscus J A
authors.initials: FJ
authors.lastname: van den Hoogen
authors.forename: Matthias A W
authors.initials: MA
authors.lastname: Merkx
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000628:therapy; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome