Synthesis of 2(R),3-dihydroxypropyl and 2(R),3(R)-dihydroxybutyl beta-D-fructopyranosides and some derivatives.
The synthesis of 2(R),3-dihydroxypropyl and 2(R),3(R)-dihydroxybutyl beta-d-fructopyranosides, and some derivatives, employing Sharpless-type catalytic asymmetric dihydroxylation procedures is described. Some aspects of the reactions, including stereoselectivities and chemical evidence for the assigned stereochemistry of the main products are reported.
Sung'hwa
Fortunatus
F
Department of Organic Chemistry, IMM Center, Radboud University Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands.
Strik
Axel
A
Regeling
Henk
H
Zwanenburg
Binne
B
Chittenden
Gordon J F
GJ
D000617:Aminoglycosides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006900:Hydroxylation; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism; D013696:Temperature
D000617:Aminoglycosides