title: Functional MRI of task switching in children with Specific Language Impairment (SLI).
abstract: The objective of this study was to examine executive functioning in children with Specific Language Impairment (SLI) using functional MRI. Six children with SLI and seven control children participated in this study and received a task-switching paradigm. No specific deficit in executive control was observed at the behavioral level in children with SLI. However, the neuroimaging data did show remarkable differences between the SLI and control children. The children with SLI recruited frontal and cingulate areas, normally associated with executive control, even when the task did not require them in the children without SLI. This might indicate that the task was more demanding for the SLI group and that compensatory mechanisms were engaged for successful task performance.
authors.affiliation: Psychiatry & Neuropsychology, University of Maastricht, 6200 MD, Maastricht, The Netherlands. P.Dibbets@np.unimaas.nl
authors.forename: Pauline
authors.initials: P
authors.lastname: Dibbets
authors.forename: Katja
authors.initials: K
authors.lastname: Bakker
authors.forename: Jellemer
authors.initials: J
authors.lastname: Jolles
mesh_terms: D000704:Analysis of Variance; D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D002648:Child; D002675:Child, Preschool; D005625:Frontal Lobe / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D007806:Language Disorders / Q000175:diagnosis* / Q000503:physiopathology; D007807:Language Tests; D008279:Magnetic Resonance Imaging; D008297:Male; D008606:Mental Processes / Q000502:physiology*; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values