title: Surgical treatment of spinal brucellosis.
abstract: We retrospectively reviewed 10 patients with spinal brucellosis of the thoracic and lumbar spine who were treated successfully with a combination of surgery and antibiotics. All patients had back pain; six patients had radiculopathy and one patient had paraparesis. Patients with spondylodiscitis without epidural abscesses (n = 3) had transpedicle discectomy and drainage. Epidural abscesses in the lumbar area caused by spondylodiscitis (n = 3), spondylitis (n = 2), and discitis with infected disc herniation (n = 1), were drained using a posterior approach combined with posterolateral fusion in two patients with spondylodiscitis and discectomy in the patient with a herniated disc. One patient presented with a pathologic fracture and neural compression and was treated with anterior corpectomy and reconstruction. Antibiotic treatment was given for 3 to 9 months. Mean followup was 3 years. Back pain improved soon after surgery. Recovery from radiculopathy and paraparesis was complete. One patient had recurrence of infection 9 months after initial treatment. Clinical manifestation of spinal brucellosis can include spondylitis, spondylodiscitis, discitis, epidural abscess, paraspinal abscess, and vertebral collapse. Transpedicle drainage allows tissue diagnosis and facilitates treatment. Because brucellosis usually responds to antibiotics, surgery is considered as the last resort in treating spinal brucellosis, but severe neurologic deficit and incapacitating back pain often necessitate surgical intervention.
  
  
  METHODS
  Therapeutic study, level IV (case series). Please see the Guidelines for Authors for a complete description of levels of evidence.
authors.affiliation: Orthopaedic Department, University Hospital of Crete, Heraklion, Greece.
authors.forename: Pavlos
authors.initials: P
authors.lastname: Katonis
authors.forename: Michael
authors.initials: M
authors.lastname: Tzermiadianos
authors.forename: Achilleas
authors.initials: A
authors.lastname: Gikas
authors.forename: Panayiotis
authors.initials: P
authors.lastname: Papagelopoulos
authors.forename: Alexander
authors.initials: A
authors.lastname: Hadjipavlou
mesh_terms: D000328:Adult; D000368:Aged; D001416:Back Pain / Q000209:etiology / Q000517:prevention & control; D002006:Brucellosis / Q000150:complications / Q000601:surgery*; D017587:Diskectomy, Percutaneous; D005260:Female; D006801:Humans; D007796:Laminectomy; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D011843:Radiculopathy / Q000453:epidemiology / Q000517:prevention & control; D012189:Retrospective Studies; D013123:Spinal Fusion; D013166:Spondylitis / Q000150:complications / Q000382:microbiology / Q000601:surgery*; D013904:Thoracic Vertebrae; D016896:Treatment Outcome