title: Treatment failure due to emergence of resistance to carbapenem during therapy for Shewanella algae bacteremia.
abstract: We describe a case of bacteremia due to imipenem-susceptible Shewanella algae. Despite treatment with imipenem, the patient developed a spinal epidural abscess, from which imipenem-resistant S. algae was isolated. The development of resistance should be monitored when S. algae infection is treated with imipenem, even though the strain is initially susceptible to imipenem.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Republic of Korea.
authors.forename: Dong-Min
authors.initials: DM
authors.lastname: Kim
authors.forename: Cheol-In
authors.initials: CI
authors.lastname: Kang
authors.forename: Chang Seop
authors.initials: CS
authors.lastname: Lee
authors.forename: Hong-Bin
authors.initials: HB
authors.lastname: Kim
authors.forename: Eui-Chong
authors.initials: EC
authors.lastname: Kim
authors.forename: Nam Joong
authors.initials: NJ
authors.lastname: Kim
authors.forename: Myoung-Don
authors.initials: MD
authors.lastname: Oh
authors.forename: Kang-Won
authors.initials: KW
authors.lastname: Choe
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology*; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008297:Male; D016133:Polymerase Chain Reaction; D020592:Shewanella / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D017211:Treatment Failure
chemical_list: D017931:DNA Primers; D004269:DNA, Bacterial; D015378:Imipenem