[The association of cardiac involvement and ischemic stroke in Churg Strauss syndrome].
In Churg and Strauss syndrome (CSS), three patterns of neurological involvement can be found, including mono or polyneuropathy, encephalopathy and stroke. We report two cases of stroke associated with major hypereosinophilia and cardiac involvement, leading to a diagnosis of CSS. Neurological and general outcome were good under treatment with steroids in combination with cyclophosphamide in one case. Churg and Strauss syndrome must be considered when a stroke is associated with a cardiac involvement and hypereosinophilia.
Sonneville
R
R
Service de Neurologie, CHU Henri Mondor, Créteil, France.
Lagrange
M
M
Guidoux
C
C
Michel
M
M
Khellaf
M
M
Russel
S
S
Hosseini
H
H
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001921:Brain / Q000473:pathology; D002545:Brain Ischemia / Q000209:etiology* / Q000473:pathology; D015267:Churg-Strauss Syndrome / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones