[Interaction of metal complexes of bacterial chlorophyll with DNA].
OBJECTIVE
Understanding the modes and activities of metal bacterial chlorophylls as PHD sensitizers with DNA.


METHODS
The modes and activities of the interaction of DNA and metal complexes of bacterial chlorophyll, which have been prepared by extraction and synthesis reaction, have been discussed according to the ultraviolet-visual spectrum and nucleic acid electrophoresis.


RESULTS
It indicates that the system of DNA and metal complexes have enchanced the interaction by the ultraviolet-visual spectrum. At the same time, it also indicates that metal complexes of bacterial chlorophyll and DNA have different combining way and have strong cutting effect in illumination by the nucleic acid electrophoresis.


CONCLUSIONS
This paper proved that metal bacterial chlorophylls as PHD sensitizers have great advantage.
Wang
Meng-liang
ML
Institute of Modern Chemistry, Shanxi University, Taiyuan 030006, China. mlwang@sxu.edu.cn
Chang
Ru-bo
RB
Liu
Dian-sheng
DS
D001429:Bacteriochlorophylls / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D003300:Copper / Q000737:chemistry; D004247:DNA / Q000378:metabolism*; D004586:Electrophoresis; D018922:HL-60 Cells; D006801:Humans; D020014:K562 Cells; D009532:Nickel / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D015032:Zinc / Q000737:chemistry
D001429:Bacteriochlorophylls; D009942:Organometallic Compounds; D003300:Copper; D009532:Nickel; D004247:DNA; D015032:Zinc