[Application of fluoroquinolons in practice of the intensive therapy departments].
The review on the most studied class of antimicrobal preparations - fluoroquinolons (FQ) - is presented. Peculiar attention is paid to FQ, which were registered in the Ukraine (ciprofloxacine, ofloxacine, gatifloxacine, moxifloxacine). The data concerning chemical structure, pharmacokinetics of FQ, obtained during last years, are presented. The advantages and faults of definite representatives of FQ class are depicted. Principles of clinical administration of FQ, basing on the departments passportization and determination of the microbic agents sensitivity, are adduced.
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D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D003422:Critical Care / Q000379:methods*; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D007362:Intensive Care Units; D015394:Molecular Structure
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones