title: Reorganization of the cortical control of movement due to radiation necrosis. Case report.
abstract: The authors report a case of reorganization of the cortical control of movement caused by radiation necrosis based on an analysis of functional magnetic resonance (fMR) imaging data acquired during a finger-tapping paradigm. Radiation necrosis in this patient extended from the parietal lobe anteriorly to the primary motor cortex (PMC), and fMR imaging demonstrated an increase in activation in the ipsilateral supplementary motor area. This is similar to the consequences of invasion by glial tumors into the PMC.
authors.affiliation: Functional Magnetic Resonance Imaging Laboratory, and Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
authors.forename: Bob L
authors.initials: BL
authors.lastname: Hou
authors.forename: Andrei I
authors.initials: AI
authors.lastname: Holodny
authors.forename: Nathan
authors.initials: N
authors.lastname: Cooperman
authors.forename: Philip H
authors.initials: PH
authors.lastname: Gutin
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D009336:Necrosis; D010296:Parietal Lobe / Q000502:physiology; D011832:Radiation Injuries / Q000150:complications*