title: The Fell pony immunodeficiency syndrome also occurs in the Netherlands: a review and six cases.
abstract: Over the last ten years a fatal syndrome associated with immunodeficiency and severe anaemia has been reported in young Fell pony foals in the UK. Affected foals are usually normal at birth but from the age of 2-4 weeks they progressively lose condition and become severely anaemic. Signs of immunodeficiency become apparent at around 3-4 weeks of age. Morbidity is low but mortality is 100% despite intensive treatment. Affected foals die or are euthanized usually before they reach the age of 3 months. A single autosomal recessive gene is suggested to be on the basis of the syndrome. Recently, affected Fell pony foals have been identified in the Netherlands and between June 2003 and August 2005, six affected Fell pony foals were referred to the Faculty of Veterinary Medicine for investigation.
authors.affiliation: Department of Equine Sciences, Internal Medicine Section, Utrecht University Yalelaan 12, 3584 CM Utrecht, The Netherlands.
authors.forename: C M
authors.initials: CM
authors.lastname: Butler
authors.forename: C M
authors.initials: CM
authors.lastname: Westermann
authors.forename: J P
authors.initials: JP
authors.lastname: Koeman
authors.forename: M M
authors.initials: MM
authors.lastname: Sloet van Oldruitenborgh-Oosterbaan
mesh_terms: D000740:Anemia / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D001947:Breeding; D017809:Fatal Outcome; D005260:Female; D006734:Horse Diseases / Q000235:genetics* / Q000276:immunology* / Q000473:pathology; D006736:Horses; D007153:Immunologic Deficiency Syndromes / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009426:Netherlands