[Kinetics of ethanol in biological sections].
Ethanol concentration in alveolocapillary blood (ACB), venous blood (VB), capillary blood (CB), saliva and urine was measured in healthy men and women aged 19-45 years 20, 40, 60, 90, 120, 180, 240 and 300 min after a single intake of 20% ethanol solution in soda water in a dose 0.8 g/kg body mass. Two types of kinetic curves were established. Calculations with Vidmark equation for different biomedia were made. Ethanol levels in all BM studied coincided in the resorption phase. In the elimination phase, ethanol concentration forms a sequence: ACB < saliva < VB < urine. Correlations and correlation coefficients of ethanol concentrations in different BM were estimated. The ethanol concentration correlation urine/ACB 1.71 +/- 0.15 and VB/ACB 1.45 +/- 0.07 is proposed for use in tests for alcohol intoxication.
Barinskaia
T O
TO
Smirnov
A V
AV
Salomatin
E M
EM
Shaev
A I
AI
D000388:Air / Q000032:analysis; D001826:Body Fluids / Q000737:chemistry*; D000431:Ethanol / Q000008:administration & dosage / Q000032:analysis* / Q000378:metabolism*; D045853:Exhalation; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D007700:Kinetics; D008297:Male
D000431:Ethanol