title: Successful management of tubercular subretinal granulomas.
abstract: OBJECTIVE
  To report the successful management of 12 eyes of 11 patients with tubercular subretinal granulomas.
  
  
  METHODS
  Eleven consecutive patients with a presumed or confirmed diagnosis of tubercular subretinal granulomas were treated with four-drug anti-tuberculosis chemotherapy with concomitant oral corticosteroids. Two patients underwent pars plana vitrectomy.
  
  
  RESULTS
  The study included seven males and four women with a median age of 30.5 years. Ten eyes responded well to medical management and a final visual acuity of 20/80 or better was achieved in eight of them. The eyes subjected to pars plana vitrectomy had a relatively worse outcome.
  
  
  CONCLUSIONS
  Tubercular subretinal granulomas are amenable to medical management provided an early diagnosis is made and treatment is initiated promptly. Once the diagnosis of presumed or confirmed tuberculosis is established, surgical intervention should be avoided.
authors.affiliation: Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Vishali
authors.initials: V
authors.lastname: Gupta
authors.forename: Amod
authors.initials: A
authors.lastname: Gupta
authors.forename: Naresh
authors.initials: N
authors.lastname: Sachdeva
authors.forename: Sunil
authors.initials: S
authors.lastname: Arora
authors.forename: P
authors.initials: P
authors.lastname: Bambery
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use*; D006099:Granuloma / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D012164:Retinal Diseases / Q000175:diagnosis / Q000628:therapy*; D012189:Retrospective Studies; D014375:Tuberculoma / Q000175:diagnosis / Q000628:therapy*; D014392:Tuberculosis, Ocular / Q000175:diagnosis / Q000628:therapy*; D014821:Vitrectomy
chemical_list: D000995:Antitubercular Agents; D004269:DNA, Bacterial; D005938:Glucocorticoids