Linezolid in the treatment of brain abscess due to Peptostreptococcus.
Brain abscesses can be caused by bacteria, fungi, and parasites. Among bacteria, anaerobic organisms include the Bacteroides species group, Fusobacterium, Peptostreptococcus, and Propionibacterium. In these cases, a 4-week course of parenteral penicillin/cefalosporin and metronidazole is the standard of treatment. We describe a case of brain abscess secondary to anaerobic infection with Peptostreptococcus, which was successfully treated with parenteral and oral linezolid after failure of standard therapy.
Salin
Federica
F
Department of Infectious and Tropical Diseases, University Hospital, Padova, Italy.
Vianello
Fabrizio
F
Manara
Renzo
R
Morelli
Erika
E
Cattelan
Annamaria
A
Scarin
Marino
M
Sgarabotto
Dino
D
D000081:Acetamides / Q000627:therapeutic use*; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001922:Brain Abscess / Q000188:drug therapy* / Q000382:microbiology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D000069349:Linezolid; D008297:Male; D023303:Oxazolidinones / Q000627:therapeutic use*; D010462:Peptostreptococcus / Q000187:drug effects*; D013788:Thalamus / Q000382:microbiology*; D016896:Treatment Outcome
D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid