title: [The association of cardiac involvement and ischemic stroke in Churg Strauss syndrome].
abstract: In Churg and Strauss syndrome (CSS), three patterns of neurological involvement can be found, including mono or polyneuropathy, encephalopathy and stroke. We report two cases of stroke associated with major hypereosinophilia and cardiac involvement, leading to a diagnosis of CSS. Neurological and general outcome were good under treatment with steroids in combination with cyclophosphamide in one case. Churg and Strauss syndrome must be considered when a stroke is associated with a cardiac involvement and hypereosinophilia.
authors.affiliation: Service de Neurologie, CHU Henri Mondor, Créteil, France.
authors.forename: R
authors.initials: R
authors.lastname: Sonneville
authors.forename: M
authors.initials: M
authors.lastname: Lagrange
authors.forename: C
authors.initials: C
authors.lastname: Guidoux
authors.forename: M
authors.initials: M
authors.lastname: Michel
authors.forename: M
authors.initials: M
authors.lastname: Khellaf
authors.forename: S
authors.initials: S
authors.lastname: Russel
authors.forename: H
authors.initials: H
authors.lastname: Hosseini
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001921:Brain / Q000473:pathology; D002545:Brain Ischemia / Q000209:etiology* / Q000473:pathology; D015267:Churg-Strauss Syndrome / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones