title: Total number of cells in the human newborn telencephalic wall.
abstract: The total cell numbers were estimated in the neocortical part of the human telencephalon in 10 normal brains of newborn babies within four major developmental zones: the cortical plate/marginal zone, the subplate, the intermediate zone and the ventricular/subventricular zone. Furthermore, the total number of neuron and glial cells was estimated in the cortical plate. The gestational ages ranged from 38 + 0-42 + 5 weeks + days of gestation. The mean total cell number was 32.6 x 10(9) (coefficient of error = 0.04) and the total number of neurons in the cortical plate 19.8 x 10(9) (coefficient of error = 0.06). This indicates that the total number of neocortical neurons equals the total number in the adults, which, however, is not the case for the glial cells.
authors.affiliation: Research Laboratory for Stereology and Neuroscience, Bispebjerg University Hospital, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Denmark. larsen-cc@hotmail.com
authors.forename: C C
authors.initials: CC
authors.lastname: Larsen
authors.forename: K
authors.initials: K
authors.lastname: Bonde Larsen
authors.forename: N
authors.initials: N
authors.lastname: Bogdanovic
authors.forename: H
authors.initials: H
authors.lastname: Laursen
authors.forename: N
authors.initials: N
authors.lastname: Graem
authors.forename: G Badsberg
authors.initials: GB
authors.lastname: Samuelsen
authors.forename: B
authors.initials: B
authors.lastname: Pakkenberg
mesh_terms: D002452:Cell Count / Q000379:methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009457:Neuroglia / Q000166:cytology*; D009474:Neurons / Q000166:cytology*; D013687:Telencephalon / Q000166:cytology* / Q000254:growth & development*