title: [Cerebral arterial infarction and diffusion tensor imaging].
abstract: OBJECTIVE
  Diffusion-weighted imaging (3 directions) and diffusion tensor imaging (9 directions) were compared for their sensitivity to detect ischemic lesion.
  
  
  METHODS
  41 patients (18 supposed transient ischemic attacks, 23 arterial stroke, MRI<or=48h) presenting with stroke syndrome were imaged using two diffusion sequences (3 directions, 2 excitations, acquisition time: 40 seconds and 9 directions, 1 excitation, acquisition time: 50 seconds, other parameters being identical). The following variables were compared (Wilcoxon test): number and extent of lesions, MRI signal and absolute ADC values, relative signal intensity and ADC ratio. Fractional anisotropy was measured within the principal lesion on the 9 directions sequence.
  
  
  RESULTS
  24 patients presented a lesion on both sequences. Four of them (including one TIA) had more lesions (<5 mm) on the 9 directions sequence than on the 3 directions sequence. Both sequences were normal for the 17 remaining patients (TIA=4, differential diagnosis=7, indeterminate=6). No significant difference was found for the other study parameters between 3 vs 9 directions sequences. There was a 10% decrease of the mean fractional anisotropy in ischemic lesion.
  
  
  CONCLUSIONS
  By showing more lesions than standard diffusion-weighted imaging and providing quantitative anisotropy measurements, diffusion tensor imaging could replace the standard 3 directions diffusion-weighted sequence.
authors.affiliation: Département d'Imagerie Morphologique et Fonctionnelle, Centre hospitalier Sainte-Anne, 1 rue Cabanis, 75674 Paris cedex 14.
authors.forename: S
authors.initials: S
authors.lastname: Rodrigo
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
authors.forename: E
authors.initials: E
authors.lastname: Touze
authors.forename: C
authors.initials: C
authors.lastname: Lamy
authors.forename: V
authors.initials: V
authors.lastname: Domigo
authors.forename: O
authors.initials: O
authors.lastname: Naggara
authors.forename: J L
authors.initials: JL
authors.lastname: Mas
authors.forename: D
authors.initials: D
authors.lastname: Fredy
authors.forename: J F
authors.initials: JF
authors.lastname: Meder
mesh_terms: D000328:Adult; D000368:Aged; D016880:Anisotropy; D002544:Cerebral Infarction / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity