title: Enterobacter sakazakii: an emerging pathogen in powdered infant formula.
abstract: Enterobacter sakazakii represents a significant risk to the health of neonates. This bacterium is an emerging opportunistic pathogen that is associated with rare but life-threatening cases of meningitis, necrotizing enterocolitis, and sepsis in premature and full-term infants. Infants aged <28 days are considered to be most at risk. Feeding with powdered infant formula (PIF) has been epidemiologically implicated in several clinical cases. Infants should be exclusively breast-fed for the first 6 months of life, and those who are not should be provided with a suitable breast-milk substitute. PIF is not a sterile product; to reduce the risk of infection, the reconstitution of powdered formula should be undertaken by caregivers using good hygienic measures and in accordance with the product manufacturer's food safety guidelines.
authors.affiliation: Centre for Food Safety, School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Ireland.
authors.forename: D
authors.initials: D
authors.lastname: Drudy
authors.forename: N R
authors.initials: NR
authors.lastname: Mullane
authors.forename: T
authors.initials: T
authors.lastname: Quinn
authors.forename: P G
authors.initials: PG
authors.lastname: Wall
authors.forename: S
authors.initials: S
authors.lastname: Fanning
mesh_terms: D044083:Cronobacter sakazakii / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity; D024881:Drug Resistance, Bacterial; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000209:etiology / Q000635:transmission; D005516:Food Microbiology; D006801:Humans; D007223:Infant; D041943:Infant Formula; D007231:Infant, Newborn; D011634:Public Health; D012449:Safety; D014774:Virulence