Endocytosis conducts the cell signaling orchestra.
Endocytosis is used by eukaryotic cells to regulate nutrient internalization, signal transduction, and the composition of the plasma membrane. However, a more complex picture is emerging, in which endocytic pathways integrate diverse signals, thereby contributing to a higher level of cellular and organismal organization. In this way, endocytosis and cell signaling are intertwined in many biological processes, such as cell motility and cell fate determination.
Polo
Simona
S
IFOM, Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20134 Milan, Italy. simona.polo@ifom-ieo-campus.it
Di Fiore
Pier Paolo
PP
D002454:Cell Differentiation / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D005057:Eukaryotic Cells / Q000166:cytology / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*