title: [Cranial diabetes insipidus in Wegener's granulomatosis].
abstract: We describe three cases of cranial diabetes insipidus (CDI) caused by Wegener's granulomatosis (WG). Panhypopituitarism was the presenting symptom in one patient. Magnetic resonance imaging (MRI) showed enlargement of the pituitary gland with an intrasellar mass lesion and absence of posterior pituitary lobe hyperintensity. Follow-up MRI disclosed reduction of the intrasellar lesion but sustained loss of posterior lobe hyperintensity. The patients still have CDI despite a marked clinical response to the treatment of WG. Pituitary dysfunction may be the presenting symptom as well as a complication of WG.
authors.affiliation: Arhus Sygehus, Medicinsk Afdeling M, Arhus C.
authors.forename: Jesper
authors.initials: J
authors.lastname: Moesgaard
authors.forename: Kasper
authors.initials: K
authors.lastname: Kjaehr
authors.forename: Bjarne Svalgaard
authors.initials: BS
authors.lastname: Thomsen
authors.forename: Edith
authors.initials: E
authors.lastname: Nielsen
authors.forename: Karin
authors.initials: K
authors.lastname: Rasmussen
authors.forename: Jens Otto Lunde
authors.initials: JO
authors.lastname: Jørgensen
mesh_terms: D020790:Diabetes Insipidus, Neurogenic / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010902:Pituitary Gland / Q000473:pathology