title: What is the best way to treat tinea cruris?
abstract: After clinical diagnosis and microscopic confirmation, tinea cruris is best treated with a topical allylamine or an azole antifungal (strength of recommendation: A, based on multiple randomized controlled trials [RCTs]). Differences in current comparison data are insufficient to stratify the 2 groups of topical antifungals. Determining which group to use depends on patient compliance, medication accessibility, and cost. The fungicidal allylamines (naftifine and terbinafine) and butenafine (allylamine derivative) are a more costly group of topical tinea treatments, yet they are more convenient as they allow for a shorter duration of treatment compared with fungistatic azoles (clotrimazole, econazole, ketoconazole, oxiconazole, miconazole, and sulconazole).
authors.affiliation: Baylor College of Medicine, Houston, TX, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Nadalo
authors.forename: Cathy
authors.initials: C
authors.lastname: Montoya
authors.forename: Dan
authors.initials: D
authors.lastname: Hunter-Smith
mesh_terms: D000287:Administration, Topical; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D005832:Genital Diseases, Male / Q000188:drug therapy*; D006801:Humans; D008297:Male; D014005:Tinea / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents