title: [Successful salvage of a patient with cardiac arrest caused by multiple pulmonary emboli and lung abscesses due to infective endocarditis of the tricuspid valve: a case report].
abstract: A 28-year-old female developed infective endocarditis in the tricuspid valve and multiple lung abscesses due to septic pulmonary emboli early after intensive therapy for ulcerative colitis. The pathogen was methicillin-resistant Staphylococcus aureus. Usual antibiotic agents and linezolid were administered. Three weeks later, she fell into cardiopulmonary arrest due to further pulmonary emboli and required mechanical circulatory assist. Fatal brain damage was suggested at first. Two days later, she fully regained consciousness and underwent tricuspid valve replacement using mechanical valve and extirpation of septic pulmonary embolus. Mechanical circulatory assist was discontinued on the next day. After strenuous administration of linezolid and other drugs for 9 weeks, she was discharged from hospital on foot. We believe that early surgical intervention should be considered in patients with infective endocarditis in the right heart and subsequent septic pulmonary emboli. Linezolid was very useful in this patient.
authors.affiliation: Department of Cardiovascular Surgery, Saitama Medical School, Morohongo 38, Moroyama-machi, Iruma-gun, Saitama 350-0459. masuoka@saitama-med.ac.jp
authors.forename: Ayumu
authors.initials: A
authors.lastname: Masuoka
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Imanaka
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Asano
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Masanori
authors.initials: M
authors.lastname: Ogiwara
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kato
authors.forename: Motonobu
authors.initials: M
authors.lastname: Nishimura
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yokote
authors.forename: Syunei
authors.initials: S
authors.lastname: Kyo
mesh_terms: D000081:Acetamides / Q000627:therapeutic use; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000150:complications*; D005112:Extracorporeal Circulation; D005260:Female; D006323:Heart Arrest / Q000209:etiology* / Q000628:therapy*; D006350:Heart Valve Prosthesis; D006801:Humans; D000069349:Linezolid; D008169:Lung Abscess / Q000150:complications* / Q000209:etiology; D016106:Methicillin Resistance; D023303:Oxazolidinones / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000150:complications*; D016879:Salvage Therapy; D013203:Staphylococcal Infections / Q000150:complications*; D014261:Tricuspid Valve
chemical_list: D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid