title: Satisfaction and tolerability of combination of lactoserum and lactic acid on the external genitalia in Thai women.
abstract: OBJECTIVE
  The aims of this study were to assess the user satisfaction and tolerability of a combination of lactoserum and lactic acid on the external genitalia of Thai women.
  
  
  METHODS
  Women who were over 18 years of age who came to gynecologic outpatient unit at Rajavithi Hospital from November 2004 to January 2005, without clinical manifestations of vulvovaginal irritation or infection were included. The exclusion criteria were women who had allergy to a combination of lactoserum and lactic acid, or any of the components of this product. Clinical history was taken and gynaecological examination was performed. Those who met the eligible criteria were assigned to use one bottle of 150 ml combination of lactoserum and lactic acid on the external genitalia. Fisher's Exact test was used to compare the satisfaction between each group.
  
  
  RESULTS
  There were 300 patients equally dividing in 3 groups. Average age was 42.2 +/- 9.8 years. The satisfaction percentage was more than 90 percent according to the evaluation criteria. There was no statistically significant difference between products. The tolerability were high percentage, only 3.3% of the patients used these products less than 7 days. 6 patients (2%) experienced discomfort resulting from these products and no statistically significant difference between products.
  
  
  CONCLUSIONS
  The combination of lactoserum and lactic acid demonstrated the high percentage of satisfaction and tolerability. Only 2% of patients experienced discomfort without any serious discomfort effects.
authors.affiliation: Obstetrics and Gynecology Infectious Unit, Department of Obstetrics and Gynecology, Rajavithi Hospital, Bangkok, Thailand.
authors.forename: Amnuay
authors.initials: A
authors.lastname: Tansupasiri
authors.forename: Apithan
authors.initials: A
authors.lastname: Puangsricharern
authors.forename: Ajcharaporn
authors.initials: A
authors.lastname: Itti-arwachakul
authors.forename: Suvanna
authors.initials: S
authors.lastname: Asavapiriyanont
mesh_terms: D000328:Adult; D000368:Aged; D004338:Drug Combinations; D005260:Female; D005836:Genitalia, Female / Q000382:microbiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007106:Immune Sera / Q000008:administration & dosage*; D007116:Immunization, Passive; D019344:Lactic Acid / Q000008:administration & dosage*; D008875:Middle Aged; D017060:Patient Satisfaction; D012915:Soaps; D013785:Thailand; D014621:Vagina / Q000378:metabolism / Q000382:microbiology; D016585:Vaginosis, Bacterial / Q000517:prevention & control*
chemical_list: D004338:Drug Combinations; D007106:Immune Sera; D012915:Soaps; C018577:lactoserum; D019344:Lactic Acid