Laboratory testing of the insect repellents IR3535 and DEET against Phlebotomus mascittii and P. duboscqi (Diptera: Psychodidae).
The efficacy of the repellent IR3535 was tested and compared with DEET using two laboratory colonies of phlebotomine sand flies, Phlebotomus mascittii and Phlebotomus duboscqi. P. duboscqi, originating from Senegal, is a proven vector of Leishmania major. P. mascittii (Corsican origin) has never been demonstrated to be a vector of leishmaniasis, but it was reported in 2004 as an anthropophilic species in Germany associated with autochthonous visceral leishmaniasis in people and animals. IR3535 and DEET were tested at an effective concentration of 10% in ethanol on two (one male, one female) human volunteers. The mean protection time against P. duboscqi was 5.9h for both repellents, against P. mascittii 10.4 and 8.8 h for IR3535 and DEET, respectively.
Naucke
Torsten J
TJ
Institute for Medical Parasitology, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany.
Lorentz
Susanne
S
Grünewald
Hans-Werner
HW
D000818:Animals; D003671:DEET; D005260:Female; D006801:Humans; D007302:Insect Repellents; D008297:Male; D010691:Phlebotomus; D011422:Propionates
D007302:Insect Repellents; D011422:Propionates; D003671:DEET; C462400:ethyl-3-(N-n-butyl-N-acetyl)aminopropionate