title: Near infrared spectroscopy in the management of status epilepticus in a young infant.
abstract: We report the medication management of electroencephalographic status epilepticus with subtle clinical manifestations in a young infant while simultaneously recording electroencephalographic activity and cerebral regional oxygen saturation (rSO(2)) index using near infrared spectroscopy (NIRS). We found that antiepileptic drugs equally influence the frequency of rSO(2) index fluctuations and electroencephalographic seizures. The purpose of this report is to illustrate the use of NIRS in the medication management of an infant with status epilepticus and subtle or no clinical manifestations; and to suggest that if future studies confirm our finding, NIRS may be reliably used to gauge the effects of antiepileptic medications in similar patients.
authors.affiliation: Division of Neonatal Neurology, Department of Neurology, Miami Children's Hospital, 3200 SW 60th Street, Miami, FL 33155, USA.
authors.forename: Gemma
authors.initials: G
authors.lastname: Arca Diaz
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Cesaron
authors.forename: Israel
authors.initials: I
authors.lastname: Alfonso
authors.forename: Catalina
authors.initials: C
authors.lastname: Dunoyer
authors.forename: Ilker
authors.initials: I
authors.lastname: Yaylali
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D006348:Cardiac Surgical Procedures; D004569:Electroencephalography; D006406:Hematoma; D006801:Humans; D007223:Infant; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D019265:Spectroscopy, Near-Infrared; D013226:Status Epilepticus / Q000188:drug therapy / Q000601:surgery* / Q000628:therapy*
chemical_list: D000927:Anticonvulsants