title: Bioinformatic challenges for the next decade(s).
abstract: The science of bioinformatics has developed in the wake of methods to determine the sequences of the informational macromolecules--DNAs, RNAs and proteins. But in a wider sense, the biological world depends in its every process on the transmission of information, and hence bioinformatics is the fundamental core of biology. We here give a consideration of some of the key problems of bioinformatics in the coming decade, and perhaps longer.
authors.affiliation: Howard Hughes Medical Institute UCLA-DOE Institute for Genomics and Proteomics Box 951570 UCLA, Los Angeles, CA 90095-1570, USA. david@mbi.ucla.edu
authors.forename: David
authors.initials: D
authors.lastname: Eisenberg
authors.forename: Edward
authors.initials: E
authors.lastname: Marcotte
authors.forename: Andrew D
authors.initials: AD
authors.lastname: McLachlan
authors.forename: Matteo
authors.initials: M
authors.lastname: Pellegrini
mesh_terms: D019295:Computational Biology / Q000639:trends*; D044127:Epigenesis, Genetic; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D023281:Genomics / Q000639:trends