title: A retrospective study of central nervous system shunt infections diagnosed in a university hospital during a 4-year period.
abstract: BACKGROUND
  Ventriculoperitoneal (VP) shunts are used for intracranial pressure management and temporary cerebrospinal fluid (CSF) drainage. Infection of the central nervous system (CNS) is a major cause of morbidity and mortality in patients with CSF shunts. The aim of the present study was to evaluate the clinical features, pathogens, and outcomes of 22 patients with CSF shunt infections collected over 4 years.
  
  
  METHODS
  The patients with shunt insertions were evaluated using; age, sex, etiology of hydrocephalus, shunt infection numbers, biochemical and microbiological parameters, prognosis, clinical infection features and clinical outcome.
  
  
  RESULTS
  The most common causes of the etiology of hydrocephalus in shunt infected patients were congenital hydrocephalus-myelomeningocele (32%) and meningitis (23%). The commonest causative microorganism identified was Staphylococcus (S.) aureus, followed by Acinetobacter spp., and S. epidermidis.
  
  
  CONCLUSIONS
  In a case of a shunt infection the timely usage of appropriate antibiotics, according to the antimicrobial susceptibility testing, and the removal of the shunt apparatus is essential for successful treatment.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Pamukkale University, Faculty of Medicine, Denizli, Turkey. suzansacar@yahoo.com
authors.forename: Suzan
authors.initials: S
authors.lastname: Sacar
authors.forename: Huseyin
authors.initials: H
authors.lastname: Turgut
authors.forename: Semra
authors.initials: S
authors.lastname: Toprak
authors.forename: Bayram
authors.initials: B
authors.lastname: Cirak
authors.forename: Erdal
authors.initials: E
authors.lastname: Coskun
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yilmaz
authors.forename: Koray
authors.initials: K
authors.lastname: Tekin
mesh_terms: D000151:Acinetobacter Infections / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D002494:Central Nervous System Infections / Q000209:etiology*; D002648:Child; D005260:Female; D006761:Hospitals; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000209:etiology; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*