title: Transarterial embolization of vein of Galen malformations: the use of magnetic resonance imaging noninvasive optimal vessel analysis to quantify shunt reduction. Report of two cases.
abstract: In patients with vein of Galen malformations, high-flow shunting decreases cerebral perfusion. By reducing or eliminating these shunts, transarterial embolization can improve cerebral perfusion and clinical outcomes. Quantifying pre- and postembolization shunt blood flow may help determine the optimal timing and efficacy of embolization and may provide prognostic information. The authors used magnetic resonance imaging noninvasive optimal vessel analysis as a novel modality to measure volumetric blood flow through vein of Galen malformation shunts in a neonate and an infant before and after transarterial embolization.
authors.affiliation: Department of Neurosurgery, Hyman-Newman Institute for Neurology and Neurosurgery, Roosevelt Hospital, New York, New York 10019, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Langer
authors.forename: Joon K
authors.initials: JK
authors.lastname: Song
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Niimi
authors.forename: Markus
authors.initials: M
authors.lastname: Chwajol
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Lefton
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Brisman
authors.forename: Walter
authors.initials: W
authors.lastname: Molofsky
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Kupersmith
authors.forename: Alejandro
authors.initials: A
authors.lastname: Berenstein
mesh_terms: D001921:Brain / Q000098:blood supply; D002550:Cerebral Veins / Q000002:abnormalities*; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D012039:Regional Blood Flow; D017287:Ventriculoperitoneal Shunt