Observations on the internal and surface morphology of malaria infected blood cells using optical and atomic force microscopy.
We describe a simple and fast method to probe the morphological changes on the exterior and interior of a malaria infected erythrocyte at different stages of parasite development. This involves the imaging and scanning of Giemsa stained malaria infected erythrocytes using optical microscopy and atomic force microscopy, respectively.
Li
Ang
A
Nano Biomechanics Laboratory, Division of Bioengineering and Department of Mechanical Engineering, National University of Singapore, Singapore 117576.
Mansoor
Ammar H
AH
Tan
Kevin S W
KS
Lim
C T
CT
D000818:Animals; D001399:Azure Stains / Q000737:chemistry*; D004396:Coloring Agents / Q000737:chemistry*; D004912:Erythrocytes / Q000469:parasitology* / Q000648:ultrastructure; D006801:Humans; D018625:Microscopy, Atomic Force / Q000379:methods*; D010963:Plasmodium falciparum / Q000254:growth & development* / Q000648:ultrastructure
D001399:Azure Stains; D004396:Coloring Agents