title: [Detection of blood opiates by fluorescence-polarization immunoassay].
abstract: It was found possible to use fluorescence-polarization immunoassay (FPIA) in screening of opium drugs in blood and blood serum as a preliminary test. The results of the study of blood and serum samples by FPIA and chromato-mass-spectroscopy were compared. As a criterion of assessment of the preliminary study results we propose to use a cutoff point by serial production of the analysed blood samples of the threshold morphine concentrations (20 ng/ml for living subjects and 40 ng/ml--for corpses). The method of opiates screening in blood proposed is characterized by fast conduction, high specificity and precision, small amounts of the expert material.
authors.forename: S S
authors.initials: SS
authors.lastname: Kataev
authors.forename: N B
authors.initials: NB
authors.lastname: Zelenina
authors.forename: D B
authors.initials: DB
authors.lastname: Oborin
authors.forename: T L
authors.initials: TL
authors.lastname: Malkova
mesh_terms: D002102:Cadaver; D016231:Fluorescence Polarization Immunoassay; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D009020:Morphine / Q000097:blood*; D012680:Sensitivity and Specificity
chemical_list: D009020:Morphine