title: Pycnogenol alleviates pain associated with pregnancy.
abstract: The effect of Pycnogenol was studied in women in the third trimester of pregnancy, complaining of lower back pain, hip joint pain, pelvic pain (pain in the inguinal region), pain due to varices or calf cramps. The women were supplemented with Pycnogenol at a dose of 30 mg/day without any other therapy. Alleviation of pain was evaluated by pain scores until delivery. A significant reduction of pain could be obtained compared with the control group, where no decrease in pain scores in any symptoms was reported. No unwanted effects were observed in the Pycnogenol group. These results indicate the potential of Pycnogenol to reduce pain associated with pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Keiju Medical Center, Tomioka-chou 94, Nanao City, Ishikawa Pref., Japan. kohama@yu.include.ne.jp
authors.forename: Takafumi
authors.initials: T
authors.lastname: Kohama
authors.forename: Masaki
authors.initials: M
authors.lastname: Inoue
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000328:Adult; D001416:Back Pain / Q000188:drug therapy; D005260:Female; D005419:Flavonoids / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D017699:Pelvic Pain / Q000188:drug therapy; D008517:Phytotherapy; D010936:Plant Extracts; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011263:Pregnancy Trimester, Third; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D005419:Flavonoids; D010936:Plant Extracts; C024070:pycnogenols