title: Diastereoselective synthesis of highly functionalized tetrahydroxanthenols--unprecedented access to privileged structural motifs.
abstract: Tetrahydroxanthenones, which can be easily prepared by a domino oxa-Michael aldol condensation, offer various possibilities for diastereoselective functionalization, giving access to the stereocontrolled synthesis of stereochemical triades or tetrades, which represent privileged structural motifs. In most cases, the relative stereochemistry was unequivocally established by crystal structure analysis.
authors.affiliation: Institut für Organische Chemie, Universität Karlsruhe TH, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.
authors.forename: Carl F
authors.initials: CF
authors.lastname: Nising
authors.forename: Ulrike K
authors.initials: UK
authors.lastname: Ohnemüller
authors.forename: Anne
authors.initials: A
authors.lastname: Friedrich
authors.forename: Bernhard
authors.initials: B
authors.lastname: Lesch
authors.forename: Jochen
authors.initials: J
authors.lastname: Steiner
authors.forename: Hansgeorg
authors.initials: H
authors.lastname: Schnöckel
authors.forename: Martin
authors.initials: M
authors.lastname: Nieger
authors.forename: Stefan
authors.initials: S
authors.lastname: Bräse
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002621:Chemistry / Q000379:methods*; D018360:Crystallography, X-Ray; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism; D014966:Xanthenes / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D006575:Heterocyclic Compounds, 3-Ring; D014966:Xanthenes; C116609:3-hydroxybutanal