Which patients taking SSRIs are at greatest risk of bleeding?
For patients at high risk of abnormal bleeding, consider prescribing an antidepressant with low serotonin reuptake inhibition, which may lower risk. For patients taking high-serotonin reuptake inhibition antidepressants, recommend avoidance or minimal use of nonsteroidal anti-inflammatory drugs and aspirin.
Mansour
Ahmed
A
St. Michael's Hospital, Medical Psychiatry Service, Toronto, Ontario M5B 1W8, Canada.
Pearce
Mark
M
Johnson
Benjamin
B
Sey
Michael Sai Lai
MS
Oda
Ninos
N
Collegala
Natasha
N
Krishnadev
Upasana
U
Bhalerao
Shree
S
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006470:Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control; D006801:Humans; D012307:Risk Factors; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D017367:Selective Serotonin Reuptake Inhibitors