Treatment of metastatic sialoblastoma with chemotherapy and surgery.
Tumors of the salivary gland are very uncommon in children. Sialoblastoma is a rare, aggressive, blastomatous, and potentially malignant congenital tumor. Distant metastases are rare. We present a case of sialoblastoma with lung metastases that developed in a 4-year-old girl adjacent to a congenital nevus in the left cheek. The tumor was inoperable at diagnosis but the largest of the pulmonary metastases was removed surgically. The patient responded well to chemotherapy and underwent surgical excision of the primary tumor, followed by three more courses of chemotherapy.
Scott
Julius X
JX
Department of Haematology-Oncology, Women's & Children's Hospital Adelaide, Australia.
Krishnan
Suren
S
Bourne
Anthony J
AJ
Williams
Michael P
MP
Agzarian
Marc
M
Revesz
Tamas
T
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002675:Child, Preschool; D005153:Facial Neoplasms / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D009508:Nevus, Pigmented / Q000473:pathology; D010307:Parotid Neoplasms / Q000473:pathology* / Q000628:therapy; D011013:Pneumonectomy; D012878:Skin Neoplasms / Q000473:pathology