An appropriate indicator for diagnosing gestational diabetes.
BACKGROUND
This study was intended to simplify the diagnostic procedure for gestational diabetes mellitus (GDM) through using a single plasma glucose level, after a 100 g oral glucose tolerance test (OGTT), as the most appropriate indicator for diagnosing GDM in pregnant women with a positive 50 g, 1-hour oral glucose challenge test (GCT) in Northern Taiwan.


METHODS
A total of 973 native Taipei metropolitan pregnant women with a positive GCT, who underwent a 100 g, 3-hour OGTT were retrospectively surveyed. GDM was defined according to the standards of National Diabetes Data Group. Plasma glucose levels, obtained 1 hour following a GCT and at multiple timing following a 100 g oral glucose load, were used to plot receiver operative characteristic curves to determine the most appropriate indicator for diagnosing GDM.


RESULTS
In the 973 pregnant women with a positive GCT, a 2-hour plasma glucose level above 165 mg/dl revealed a sensitivity and specificity of 91.2% and 90.3%, respectively.


CONCLUSIONS
To simplify the diagnostic procedure for GDM, we suggest that a 2-hour plasma glucose level above 165 mg/dl after a 100 g OGTT might be an appropriate indicator for diagnosing GDM in women with a positive GCT.
Sun
Jui-Hung
JH
Division of Endocrinology & Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei.
See
Lai-Chu
LC
Chiu
Tsung-Hong
TH
Hsieh
T'sang-T'ang
TT
Huang
Miau-Ju
MJ
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D016640:Diabetes, Gestational / Q000175:diagnosis*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D012372:ROC Curve; D012189:Retrospective Studies
D001786:Blood Glucose