title: [Nonvaccine Streptococcus pneumoniae serotypes causing acute bacterial meningitis].
abstract: The pneumococcal heptavalent conjugate vaccine protects children aged less than 2 years old from invasive pneumococcal disease (IPD). Efficacy is 89-93% in the US population and 71-86% in European studies. The vaccine confers active immunization against the main serotypes causing IPD (4, 6B, 9V, 14, 18C, 19F y 23F). We describe 2 children who presented with pneumococcal meningitis caused by nonvaccine serotypes. As a result of the widespread use of the heptavalent vaccine, there may be a shift in the serotypes causing IPD.
authors.affiliation: Servicio de Pediatría, Hospital Universitario de Girona Doctor Josep Trueta, Girona, Spain. DRLUKE69@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Luque Moreno
authors.forename: A
authors.initials: A
authors.lastname: Bergadà Masó
authors.forename: J M
authors.initials: JM
authors.lastname: Sin Opi
authors.forename: A
authors.initials: A
authors.lastname: Liarte Guillén
authors.forename: L
authors.initials: L
authors.lastname: Mayol
authors.forename: J
authors.initials: J
authors.lastname: Macià Martí
mesh_terms: D005260:Female; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D008297:Male; D008586:Meningitis, Pneumococcal / Q000382:microbiology*; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification*; D018074:Vaccines, Conjugate
chemical_list: D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate