title: [Growth hormone treatment of short children born small for gestational age].
abstract: Short children born small for gestational age (SGA) are defined as having a birth weight below -2 SD for gestational age and a reduced height at four years of age (height < -2.5 SD). Growth hormone (GH) treatment significantly improves final height (mean height gain 12 centimetres) in such children. Consequently, GH therapy has been an approved indication in Europe since 2003 for SGA children who remain short at four years of age. The Danish consensus guidelines for diagnosis, treatment and control of short SGA children are described in this review.
authors.affiliation: Odense Universitetshospital, Børneafdelingen, H:S Rigshospitalet, Afdeling for Vaekst.
authors.forename: Henrik B Thybo
authors.initials: HB
authors.lastname: Christesen
authors.forename: Rikke Bodin Beck
authors.initials: RB
authors.lastname: Jensen
authors.forename: Niels H
authors.initials: NH
authors.lastname: Birkebaek
authors.forename: Niels Thomas
authors.initials: NT
authors.lastname: Hertel
authors.forename: Katharina M
authors.initials: KM
authors.lastname: Main
authors.forename: Henrik B
authors.initials: HB
authors.lastname: Mortensen
authors.forename: Rune W
authors.initials: RW
authors.lastname: Naeraa
authors.forename: Anders
authors.initials: A
authors.lastname: Juul
mesh_terms: D001827:Body Height / Q000187:drug effects; D002675:Child, Preschool; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006130:Growth Disorders / Q000188:drug therapy* / Q000209:etiology; D013006:Growth Hormone / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic
chemical_list: D013006:Growth Hormone