Panton-Valentine leukocidin-producing Staphylococcus aureus infections: report of 4 French cases.
We report 4 cases of community-acquired infections due to Staphylococcus aureus producing Panton-Valentin leukocidin (SA-PVL) with uncommon multivisceral localizations. These cases highlight the need to screen for PVL in patients with serious staphylococcal infections. All patients were cured. Two of them received intravenous immunoglobulins in addition to antibiotics.
Salliot
Carine
C
Service de Médecine Interne et Rhumatologie et, Groupe Hospitalier Diaconesses--La Croix-Saint Simon, Paris, France. carinesalliot@wanadoo.fr
Zeller
Valerie
V
Puechal
Xavier
X
Manceron
Veronique
V
Sire
Stephane
S
Varache
Nicolas
N
Etienne
Jerome
J
Desplaces
Nicole
N
Ziza
Jean-Marc
JM
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000235:genetics; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D005098:Exotoxins / Q000096:biosynthesis* / Q000235:genetics; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007956:Leukocidins; D008297:Male; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000472:pathogenicity; D014781:Viscera / Q000382:microbiology / Q000473:pathology
D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D016756:Immunoglobulins, Intravenous; D007956:Leukocidins; C078284:Panton-Valentine leukocidin