title: Panton-Valentine leukocidin-producing Staphylococcus aureus infections: report of 4 French cases.
abstract: We report 4 cases of community-acquired infections due to Staphylococcus aureus producing Panton-Valentin leukocidin (SA-PVL) with uncommon multivisceral localizations. These cases highlight the need to screen for PVL in patients with serious staphylococcal infections. All patients were cured. Two of them received intravenous immunoglobulins in addition to antibiotics.
authors.affiliation: Service de Médecine Interne et Rhumatologie et, Groupe Hospitalier Diaconesses--La Croix-Saint Simon, Paris, France. carinesalliot@wanadoo.fr
authors.forename: Carine
authors.initials: C
authors.lastname: Salliot
authors.forename: Valerie
authors.initials: V
authors.lastname: Zeller
authors.forename: Xavier
authors.initials: X
authors.lastname: Puechal
authors.forename: Veronique
authors.initials: V
authors.lastname: Manceron
authors.forename: Stephane
authors.initials: S
authors.lastname: Sire
authors.forename: Nicolas
authors.initials: N
authors.lastname: Varache
authors.forename: Jerome
authors.initials: J
authors.lastname: Etienne
authors.forename: Nicole
authors.initials: N
authors.lastname: Desplaces
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Ziza
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000235:genetics; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D005098:Exotoxins / Q000096:biosynthesis* / Q000235:genetics; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007956:Leukocidins; D008297:Male; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000472:pathogenicity; D014781:Viscera / Q000382:microbiology / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D016756:Immunoglobulins, Intravenous; D007956:Leukocidins; C078284:Panton-Valentine leukocidin