Treatment failure due to emergence of resistance to carbapenem during therapy for Shewanella algae bacteremia.
We describe a case of bacteremia due to imipenem-susceptible Shewanella algae. Despite treatment with imipenem, the patient developed a spinal epidural abscess, from which imipenem-resistant S. algae was isolated. The development of resistance should be monitored when S. algae infection is treated with imipenem, even though the strain is initially susceptible to imipenem.
Kim
Dong-Min
DM
Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Republic of Korea.
Kang
Cheol-In
CI
Lee
Chang Seop
CS
Kim
Hong-Bin
HB
Kim
Eui-Chong
EC
Kim
Nam Joong
NJ
Oh
Myoung-Don
MD
Choe
Kang-Won
KW
D000368:Aged; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology*; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008297:Male; D016133:Polymerase Chain Reaction; D020592:Shewanella / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D017211:Treatment Failure
D017931:DNA Primers; D004269:DNA, Bacterial; D015378:Imipenem