Synthesis and application of a fluorous Lawesson's reagent: convenient chromatography-free product purification.
[reaction: see text] A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction.
Kaleta
Zoltan
Z
Institute of Biomolecular Chemistry, Chemical Research Center of the Hungarian Academy of Science, P.O. Box 17, 1525 Budapest, Hungary.
Tarkanyi
Gabor
G
Gömöry
Agnes
A
Kalman
Ferenc
F
Nagy
Tamas
T
Soós
Tibor
T