Differential interhemispheric cooling and ICP compartmentalization in a patient with left ICA occlusion.
We report a case of a 69-year-old white female who presented with a large left internal carotid artery occlusive stroke from a cardiogenic embolus. She was enrolled in an institutional study using a specially designed cooling helmet. Bilateral intracranial pressure (ICP) and temperature probes were placed to determine if there was any differential cooling and ICP compartmentalization between the two hemispheres. We demonstrated a significant temperature gradient between the infarcted and the non-infarcted hemisphere. A significant inter-hemispheric ICP gradient was also observed. We believe that this is the first demonstration of preferential cooling of the infarcted hemisphere over the non-infarcted hemisphere with regional surface hypothermia.
Wang
H
H
Department of Neurosurgery, O.S.F Stroke Network, Illinois Neurological Institute, University of Illinois College of Medicine at Peoria, Peoria, Illinois 61656, USA.
Wang
D
D
Lanzino
G
G
Elkins
W
W
Olivero
W
W
D000368:Aged; D001831:Body Temperature / Q000502:physiology*; D001929:Brain Edema / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy; D020520:Brain Infarction / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy*; D002341:Carotid Artery Thrombosis / Q000503:physiopathology / Q000628:therapy*; D019610:Cytoprotection / Q000502:physiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D019586:Intracranial Hypertension / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy; D008991:Monitoring, Physiologic / Q000592:standards; D013687:Telencephalon / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology*; D013821:Thermometers / Q000592:standards; D017211:Treatment Failure