title: An analysis of the Home Office Statistics of Scientific Procedures on Living Animals, Great Britain 2004.
abstract: The 2004 Statistics of Scientific Procedures on Living Animals were released by the Home Office in December 2005. They indicate that, for the third year running, there has been a significant increase in the number of laboratory animal procedures undertaken in Great Britain, and that increasing numbers of animals are involved. The overall trends in the use of toxicological and non-toxicological procedures involving animals are described. Particular emphasis is placed on the production and use of genetically modified animals, the production of biological materials, and acute toxicity testing. The use of non-human primates and dogs is also discussed. The implications of these latest statistics are considered with reference to the implementation of the Three Rs and their consequences for animal welfare.
authors.affiliation: FRAME, Nottingham, NG1 4EE, UK. michelle@frame.org.uk
authors.forename: Michelle
authors.initials: M
authors.lastname: Hudson
authors.forename: Nirmala
authors.initials: N
authors.lastname: Bhogal
mesh_terms: D032761:Animal Experimentation / Q000706:statistics & numerical data; D000826:Animal Testing Alternatives; D000827:Animal Welfare; D000818:Animals; D000830:Animals, Laboratory; D001688:Biological Products; D023382:Toxicity Tests, Acute; D014116:Toxicology / Q000331:legislation & jurisprudence / Q000379:methods* / Q000639:trends; D006113:United Kingdom
chemical_list: D001688:Biological Products