Use of flocked swabs and a universal transport medium to enhance molecular detection of Chlamydia trachomatis and Neisseria gonorrhoeae.
The use of new flocked swabs, compared to kit swabs, enhanced the ability of three commercial nucleic acid amplification tests to detect low levels of Chlamydia trachomatis and Neisseria gonorrhoeae nucleic acids when the organisms were diluted in a universal transport medium as mocked specimens.
Chernesky
Max
M
McMaster University, St. Joseph's Healthcare and Father Sean O'Sullivan Research Centre, 50 Charlton Ave. East, Hamilton, ON L8N 4A6, Canada. chernesk@mcmaster.ca
Castriciano
Santina
S
Jang
Dan
D
Smieja
Marek
M
D001431:Bacteriological Techniques / Q000295:instrumentation / Q000706:statistics & numerical data; D002584:Cervix Uteri / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics* / Q000302:isolation & purification*; D003470:Culture Media; D005260:Female; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000235:genetics* / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques / Q000295:instrumentation / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity
D003470:Culture Media