title: Local morphology predicts functional organization of the dorsal premotor region in the human brain.
abstract: A confusing picture of the functional organization of the dorsal premotor region of the human brain emerged when functional neuroimaging studies that either examined visuomotor hand conditional activity or attempted to localize the human frontal eye field reported activity increases at the same general location, namely the junction of the superior precentral sulcus with the superior frontal sulcus. The present functional magnetic resonance imaging study examined visuomotor hand conditional activity and the locus of the frontal eye field as defined by a standard task, on a subject-by-subject basis, to clarify their location and reveal relationships between the pattern of local morphology and functional activity. The results demonstrate that visuomotor hand conditional activity and the frontal eye field lie within distinct parts of the superior precentral sulcus, revealing an organization of the human premotor cortex consistent with that observed in experimental studies in the monkey.
authors.affiliation: Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada. camiez@bic.mni.mcgill.ca
authors.forename: Céline
authors.initials: C
authors.lastname: Amiez
authors.forename: Penelope
authors.initials: P
authors.lastname: Kostopoulos
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Champod
authors.forename: Michael
authors.initials: M
authors.lastname: Petrides
mesh_terms: D000328:Adult; D000818:Animals; D001931:Brain Mapping; D005260:Female; D006225:Hand / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D009044:Motor Cortex / Q000033:anatomy & histology / Q000098:blood supply / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010296:Parietal Lobe / Q000098:blood supply / Q000502:physiology*; D011237:Predictive Value of Tests; D011597:Psychomotor Performance / Q000502:physiology*; D012438:Saccades / Q000502:physiology
chemical_list: D010100:Oxygen