[Cranial diabetes insipidus in Wegener's granulomatosis].
We describe three cases of cranial diabetes insipidus (CDI) caused by Wegener's granulomatosis (WG). Panhypopituitarism was the presenting symptom in one patient. Magnetic resonance imaging (MRI) showed enlargement of the pituitary gland with an intrasellar mass lesion and absence of posterior pituitary lobe hyperintensity. Follow-up MRI disclosed reduction of the intrasellar lesion but sustained loss of posterior lobe hyperintensity. The patients still have CDI despite a marked clinical response to the treatment of WG. Pituitary dysfunction may be the presenting symptom as well as a complication of WG.
Moesgaard
Jesper
J
Arhus Sygehus, Medicinsk Afdeling M, Arhus C.
Kjaehr
Kasper
K
Thomsen
Bjarne Svalgaard
BS
Nielsen
Edith
E
Rasmussen
Karin
K
Jørgensen
Jens Otto Lunde
JO
D020790:Diabetes Insipidus, Neurogenic / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010902:Pituitary Gland / Q000473:pathology