title: DNA-templated assembly of nanoscale architectures for next-generation electronic devices.
abstract: We report the assembly and structural characterization of a Y-shaped DNA template incorporating a central biotin moiety. We also report that this template may be used assemble nanoscale architectures, which demonstrate the potential of this and related approaches to the fabrication of next-generation electronic devices. Of particular significance is the finding that it is possible to selectively metallize the above DNA template to obtain a three-electrode configuration. Also of particular significance is finding that a biotin modified nanoparticle will recognize and bind selectively the central biotin moiety of the same template, once functionalized by the protein streptavidin.
authors.affiliation: Department of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Sarmiza Elena
authors.initials: SE
authors.lastname: Stanca
authors.forename: Ramon
authors.initials: R
authors.lastname: Eritjab
authors.forename: Donald
authors.initials: D
authors.lastname: Fitzmaurice
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D003460:Crystallization / Q000379:methods; D004247:DNA / Q000737:chemistry*; D004581:Electronics; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D008839:Microelectrodes; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D013499:Surface Properties; D014173:Transistors, Electronic
chemical_list: D020099:Coated Materials, Biocompatible; D004247:DNA