title: [Regulation of myocardial lysosomal enzyme activity by calcium].
abstract: Calcium channel blockers, verapamil and diltiazem, reduce calcium overloading of cardiomyocytes and limit activation of myocardial lysosomal enzymes under conditions of acute hypoxia, acute total ischemia of myocardium and experimental hyperlipidemia.
authors.forename: B K
authors.initials: BK
authors.lastname: Romanov
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D004110:Diltiazem / Q000494:pharmacology; D006949:Hyperlipidemias / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D017202:Myocardial Ischemia / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology* / Q000473:pathology; D032383:Myocytes, Cardiac / Q000201:enzymology*; D051381:Rats; D014700:Verapamil / Q000494:pharmacology
chemical_list: D002121:Calcium Channel Blockers; D014700:Verapamil; D004110:Diltiazem; D002118:Calcium