title: Speech arrest with stimulation may not reliably predict language deficit after epilepsy surgery.
abstract: The authors present a patient in whom electrical cortical stimulation of the posterior temporal cortex induced speech arrest, comprehension deficits, and other language-related impairments. This area was ultimately resected because of persistence of a severe seizure disorder. No postoperative aphasia was observed despite the cortical stimulation results, and the patient is since seizure free. These findings question the well-established principle that corticography directly reflects local cortical functions in all patients.
authors.affiliation: Presurgical Epilepsy Evaluation Unit, Functional Neurology and Neurosurgery Program, University of Geneva, Switzerland. margitta.seeck@hcuge.ch
authors.forename: M
authors.initials: M
authors.lastname: Seeck
authors.forename: A J
authors.initials: AJ
authors.lastname: Pegna
authors.forename: S
authors.initials: S
authors.lastname: Ortigue
authors.forename: L
authors.initials: L
authors.lastname: Spinelli
authors.forename: C A
authors.initials: CA
authors.lastname: Dessibourg
authors.forename: J
authors.initials: J
authors.lastname: Delavelle
authors.forename: O
authors.initials: O
authors.lastname: Blanke
authors.forename: C M
authors.initials: CM
authors.lastname: Michel
authors.forename: T
authors.initials: T
authors.lastname: Landis
authors.forename: J-G
authors.initials: JG
authors.lastname: Villemure
mesh_terms: D000328:Adult; D002552:Cerebral Ventricles / Q000473:pathology; D004827:Epilepsy / Q000601:surgery*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007806:Language Disorders / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D013064:Speech Disorders / Q000503:physiopathology*; D013514:Surgical Procedures, Operative / Q000009:adverse effects