title: Avascular necrosis of the femoral head as the first manifestation of acute lymphoblastic leukemia.
abstract: Avascular necrosis of bone is a well-described complication of cancer chemotherapy containing corticosteroids and has been observed in lymphomas and acute lymphoblastic leukemia (ALL). This study reports the case of a young male patient in whom avascular necrosis of right femur head was the presenting feature of acute lymphoblastic leukemia. The temporal association in this instance implicates a pathophysiologic relationship between the development of ALL and necrosis.
authors.affiliation: Department of Hematology, Cukurova Unviersity Medical School, Adana, Turkey. egurkan@cu.edu.tr
authors.forename: Emel
authors.initials: E
authors.lastname: Gürkan
authors.forename: Ismail
authors.initials: I
authors.lastname: Yildiz
authors.forename: Faith
authors.initials: F
authors.lastname: Oçal
mesh_terms: D000328:Adult; D005271:Femur Head Necrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D011859:Radiography; D012074:Remission Induction; D012680:Sensitivity and Specificity; D016896:Treatment Outcome