Recurrent acute stent thrombosis associated with protein C and S deficiencies.
Protein C and protein S deficiencies may uncommonly be responsible for coronary arterial thrombosis. We report a young woman with recurrent acute stent thrombosis due to the deficiency of protein C and S. After coronary stenting, stent thrombosis occurred two times despite aggressive antiplatelet therapy, including aspirin, clopidogrel and glycoprotein IIb/IIIa inhibitor. This report suggests that the deficiency of protein C and S should be born in mind in a young patient with recurrent thrombotic events, and that anticoagulants in addition to antiplatelet agents considered in the presence of their deficiency.
Acar
Gurkan
G
Department of Cardiology, Sevket Demirel Heart Center, Suleyman Demirel University, Isparta, Turkey. gurkandracar@hotmail.com
Dogan
Abdullah
A
Altinbas
Ahmet
A
Turker
Yasin
Y
D000208:Acute Disease; D000328:Adult; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000517:prevention & control; D004562:Electrocardiography; D005260:Female; D006801:Humans; D020151:Protein C Deficiency / Q000150:complications*; D018455:Protein S Deficiency / Q000150:complications*; D012008:Recurrence; D015607:Stents / Q000009:adverse effects*