Huge pericardial rhabdomyoma with hypoplastic left ventricle and lung.
We describe the clinical course and autopsy findings of a female fetus with hydrops fetalis due to a huge pericardial rhabdomyoma. Fetal echocardiography at 21 weeks gestation demonstrated a huge tumor in the left ventricle. The fetus died of hydrops fetalis due to cardiac dysfunction at 24 weeks gestation. Autopsy demonstrated that the tumor protruded from the epicardial region of the apex into the pericardial cavity and induced a hypoplastic left ventricle and lung. Microscopically, the cardiac tumor showed characteristics of rhabdomyoma. This localization of cardiac rhabdomyoma is rare, but we remain aware of the possibility of an unusual and rapid progression of cardiac rhabdomyoma.
Takeuchi
Makoto
M
Department of Pathology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Nakayama
Masahiro
M
Kuwae
Yuko
Y
Hamana
Keiko
K
Inamura
Noboru
N
Suehara
Noriyuki
N
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D001344:Autopsy; D001707:Biopsy, Needle; D004452:Echocardiography / Q000379:methods; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D005318:Fetal Heart / Q000002:abnormalities*; D005865:Gestational Age; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007150:Immunohistochemistry; D008168:Lung / Q000002:abnormalities*; D008423:Maternal Age; D010496:Pericardium / Q000473:pathology; D011247:Pregnancy; D012207:Rhabdomyoma / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D016216:Ultrasonography, Prenatal