title: Alcohol-attributable mortality and potential years of life lost in Canada 2001: implications for prevention and policy.
abstract: BACKGROUND
  Alcohol is one of the most important risk factors for burden of disease.
  
  
  OBJECTIVE
  To estimate the number of deaths and the years of life lost attributable to alcohol for Canada 2001 using different ways to measure alcohol exposure.
  
  
  METHODS
  Distribution of exposure was taken from a major national survey of Canada, the Canadian Addiction Survey, and corrected for per capita consumption from production and sales. For chronic disease, risk relations were taken from the published literature and combined with exposure to calculate age- and sex-specific alcohol-attributable fractions (AAFs). For injury, AAFs were taken directly from available statistics. Information on mortality, with cause of death coded according to the International Classification of Diseases version 10 (ICD-10) was obtained from Statistics Canada.
  
  
  RESULTS
  For Canada in 2001, 4,010 of all deaths in the group below 70 years of age were attributable to alcohol, 3,132 in men and 877 in women. This constituted 6.0% of all deaths in Canada in this age group, 7.6% for men, and 3.5% for women. The 4,010 deaths are a net figure, already taking into account the deaths prevented by moderate consumption of alcohol. Main causes of alcohol-attributable death were unintentional injuries, malignant neoplasms and digestive diseases. Ischaemic heart disease (IHD) was the biggest cause of death prevented by alcohol, with 78.7% of all alcohol-attributable prevented deaths in the age groups of 70 years and above. A total of 144,143 years of life were lost prematurely in Canada in that year, 113,079 years in men and 31,063 years in women.
  
  
  CONCLUSIONS
  Regardless of the assumptions made, alcohol is a major contributor to mortality in Canada. The impact of alcohol on social life is not confined to mortality, as other studies indicated that alcohol is linked even more strongly to disability and social harm. Alcohol-attributable harm could be substantially reduced, however, if known effective policies were introduced.
authors.affiliation: Centre for Addiction and Mental Health, Toronto, Canada. jtrehm@aol.com
authors.forename: Jürgen
authors.initials: J
authors.lastname: Rehm
authors.forename: Jayadeep
authors.initials: J
authors.lastname: Patra
authors.forename: Svetlana
authors.initials: S
authors.lastname: Popova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects / Q000401:mortality*; D019973:Alcohol-Related Disorders / Q000209:etiology / Q000401:mortality*; D000435:Alcoholic Intoxication / Q000150:complications / Q000401:mortality; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008017:Life Expectancy; D008297:Male; D008875:Middle Aged; D012307:Risk Factors