Long-term remission in progressive multifocal leukoencephalopathy caused by idiopathic CD4+ T lymphocytopenia: a case report.
Progressive multifocal leukoencephalopathy is caused by JC virus, an opportunistic infection of the central nervous system. Antiretroviral treatment for progressive multifocal leukoencephalopathy in human immunodeficiency virus-infected patients is beneficial, but few data exist for patients who are not infected with human immunodeficiency virus. Idiopathic CD4+ T lymphocytopenia excludes human immunodeficiency virus infection. We describe a patient with progressive multifocal leukoencephalopathy with underlying idiopathic CD4+ T lymphocytopenia in whom functional recovery occurred without antiviral therapy.
Rueger
M A
MA
Department of Neurology, University Hospital of Cologne, Cologne, Germany.
Miletic
H
H
Dorries
K
K
Wyen
C
C
Eggers
C
C
Deckert
M
M
Faetkenheuer
G
G
Jacobs
A H
AH
D000328:Adult; D006801:Humans; D007577:JC Virus / Q000302:isolation & purification; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008297:Male; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications*