title: Reaction of dimethoxycarbene-DMAD zwitterion with 1,2-diones and anhydrides: a novel synthesis of highly substituted dihydrofurans and spirodihydrofurans.
abstract: The zwitterion formed by the reaction of dimethoxycarbene and DMAD adds efficiently to one of the carbonyl groups of 1,2-dicarbonyl compounds and anhydrides to generate dihydrofurans and spirodihydrofurans in good yields. In many cases, the carbene inserts into the C-C bond of the dione to yield masked vicinal tricarbonyl systems.
authors.affiliation: Organic Chemistry Division, Regional Research Laboratory (CSIR), Trivandrum, India. vijaynair_2001@yahoo.com
authors.forename: Vijay
authors.initials: V
authors.lastname: Nair
authors.forename: Ani
authors.initials: A
authors.lastname: Deepthi
authors.forename: Manojkumar
authors.initials: M
authors.lastname: Poonoth
authors.forename: Bindu
authors.initials: B
authors.lastname: Santhamma
authors.forename: Sreekumar
authors.initials: S
authors.lastname: Vellalath
authors.forename: Beneesh Pattoorpady
authors.initials: BP
authors.lastname: Babu
authors.forename: Resmi
authors.initials: R
authors.lastname: Mohan
authors.forename: Eringathodi
authors.initials: E
authors.lastname: Suresh
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000812:Anhydrides / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D006838:Hydrocarbons / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D000812:Anhydrides; D005663:Furans; D006838:Hydrocarbons; D007659:Ketones; D013141:Spiro Compounds; C030011:carbene; C022918:acetylenedicarboxylic acid dimethyl ester; D008697:Methane