[A case report of autoimmune pancreatitis with Mikulicz' s disease and diabetes mellitus].
A 56-year-old man with bilateral swelling of lacrimal glands was admitted to our hospital. He was diagnosed as autoimmune pancreatitis with Mikulicz' s disease presenting the swelling of lacrimal glands, submandibular glands and the pancreas head and tail. Treatment with systemic prednisolone resulted in improvement of the swelling of these glands and pancreas. On the immunohistochemical examination, infiltration of CD4- and CD8-positive T lymphocytes was detected in the lacrimal gland, the submandibular gland, the gall bladder and the pancreas. Infiltration of IgG4-positive plasma cells was detected in the submandibular gland, the gall bladder and the pancreas. These results may suggest the presence of common etiology between autoimmune pancreatitis and Mikulicz' s disease.
Takagi
Tomoyuki
T
The First Department of Internal Medicine, Wakayama Medical University.
Doi
Takuya
T
Sakamoto
Hirokazu
H
Tatsuta
Hitomi
H
Kobayashi
Yasuhito
Y
Tsubota
Yukari
Y
Nishino
Masayuki
M
Nakano
Yoshio
Y
Wakasaki
Hisao
H
Furuta
Hiroto
H
Nanjo
Kishio
K
D001327:Autoimmune Diseases / Q000150:complications*; D048909:Diabetes Complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D008882:Mikulicz' Disease / Q000150:complications*; D010195:Pancreatitis / Q000150:complications*