Functional genomics of early cortex patterning.
Several lines of evidence have illuminated the fundamental developmental principles involved in establishing and implementing pattern formation in the mammalian neocortex. A recent study has sought to unravel the underlying genetic control of cortex patterning by elucidating the transcriptional profile of discrete neocortical regions.
Chambers
David
D
Wellcome Trust Functional Genomics Development Initiative, MRC Centre for Developmental Neurobiology, King's College London, Guy's Campus, London SE1 1UL, UK. david.2.chambers@kcl.ac.uk
Fishell
Gord
G
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D002540:Cerebral Cortex / Q000378:metabolism*; D005346:Fibroblast Growth Factors / Q000378:metabolism; D005786:Gene Expression Regulation; D023281:Genomics / Q000379:methods*; D006801:Humans; D019579:Neocortex / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism
D014157:Transcription Factors; D005346:Fibroblast Growth Factors