[Fertility of Drosophila melanogaster females affected by mutation l(2)M167DTS].
We studied the fertility of D. melanogaster females heterozygous for the dominant temperature sensitive mutation l(2)M167DTS, which exerts a recessive lethal effect at 25 degrees C, under the conditions of stable temperature regimes 25, 28, and 29 degrees C and changing regimes 25-->29 degrees C and 29-->25 degrees C. It was shown that inhibition of total activity of oogenesis due to a decreased number of functioning ovarioles is one of the mechanisms underlying the decreased fertility of l(2)M167DTS /+ females. Analysis of individual fertility of each female confirmed also the role of sterility as a component of fertility of the females. Sterilization was realized due both to full depletion of functioning ovarioles and disturbed mechanism of laying the mature eggs onto a substrate as a result of violation of the feedback blocking normal ovulation, which led to the breakdown of ovarioles and filling of the abdominal cavity with mature oocytes. A significant polymorphism of heterozygous females by their fertility was observed. The intensity of sterilization and mortality of l(2)M167DTS/+ females sharply increased at an elevated temperature (29 degrees C), especially at the pupal stage.
Kulikov
A M
AM
Miasniankina
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EN
D000818:Animals; D004331:Drosophila melanogaster; D005260:Female; D005298:Fertility / Q000235:genetics; D005799:Genes, Dominant / Q000235:genetics*; D017344:Genes, Insect / Q000235:genetics*; D006579:Heterozygote; D006358:Hot Temperature; D009154:Mutation; D010058:Oviposition / Q000235:genetics*; D040641:Quantitative Trait Loci / Q000235:genetics*