title: Social perception as a mediator of the influence of early visual processing on functional status in schizophrenia.
abstract: OBJECTIVE
  The potential of social cognition as a mediator of relations between neurocognition and functional status in schizophrenia has been suggested by correlational studies that link neurocognition to social cognition or link social cognition to functional status. The authors used structural equation modeling to test more directly whether one aspect of social cognition (social perception) mediates relations between basic visual perception and functional status in patients with schizophrenia.
  
  
  METHODS
  Seventy-five outpatients with schizophrenia were administered measures of early visual processing (computerized visual masking procedures), social perception (Half Profile of Nonverbal Sensitivity), and functional status (Role Functioning Scale).
  
  
  RESULTS
  Structural equation modeling supported social perception as a mediator of relations between early visual processing and functional status in schizophrenia. The mediation model indicated that early visual processing is linked to functional status through social perception, thereby supporting a significant indirect relationship. The direct relationship between early visual processing and functional status was significant in a model that did not include social perception but was not significant in the mediation model that included social perception.
  
  
  CONCLUSIONS
  Social cognition appears to be a key determinant of functional status in schizophrenia. Using a very basic measure of visual perception, the present study found that social perception mediates the influence of early visual processing on functional status in schizophrenia.
authors.affiliation: Department of Psychology, California State University, Northridge, CA 91330-8255, USA. mark.sergi@csun.edu
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Sergi
authors.forename: Yuri
authors.initials: Y
authors.lastname: Rassovsky
authors.forename: Keith H
authors.initials: KH
authors.lastname: Nuechterlein
authors.forename: Michael F
authors.initials: MF
authors.lastname: Green
mesh_terms: D000553:Ambulatory Care; D003072:Cognition Disorders / Q000175:diagnosis*; D003463:Cues; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D010470:Perceptual Masking / Q000502:physiology; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012917:Social Adjustment; D012938:Social Perception; D014796:Visual Perception / Q000502:physiology*