title: Deep vein thrombosis prevention in joint arthroplasties: continuous enhanced circulation therapy vs low molecular weight heparin.
abstract: Deep vein thrombosis prevention efficacy using a new, miniature, mobile, battery-operated pneumatic system (continuous enhanced circulation therapy [CECT] system) combined with low-dose aspirin was compared to enoxaparin. One hundred twenty-one patients who underwent total hip or knee arthroplasty were prospectively randomized into 2 groups. The study group was treated by the CECT system starting immediately after the induction of anesthesia. Postoperatively, a daily 100-mg aspirin tablet was added. The control group received 40 mg of enoxaparin per day. Bilateral venography was performed at the fifth to eight postoperative day. In the CECT group, as compared to the enoxaparin group, there was a significantly lower overall rate of DVT and proximal DVT. Safety profiles were similar in both groups. The combination of the CECT device with low-dose aspirin is more effective than enoxaparin in preventing deep-vein thrombosis after lower limb arthroplasties.
authors.affiliation: Department of Orthopedics, Assaf Harofe Medical Center, Zeriffin, Israel.
authors.forename: Yael
authors.initials: Y
authors.lastname: Gelfer
authors.forename: Hovav
authors.initials: H
authors.lastname: Tavor
authors.forename: Amir
authors.initials: A
authors.lastname: Oron
authors.forename: Amir
authors.initials: A
authors.lastname: Peer
authors.forename: Nahum
authors.initials: N
authors.lastname: Halperin
authors.forename: Dror
authors.initials: D
authors.lastname: Robinson
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D001241:Aspirin / Q000627:therapeutic use*; D017984:Enoxaparin / Q000627:therapeutic use*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D020246:Venous Thrombosis / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D017984:Enoxaparin; D005343:Fibrinolytic Agents; D001241:Aspirin