title: [Effect of extracted liquid from qianlietongyu on the proliferation and apoptosis on prostatic smooth muscle cells in vitro].
abstract: OBJECTIVE
  To explore the effect of extracted liquid from Qianlietongyu on the proliferation or apoptosis on prostatic smooth muscle cells in vitro.
  
  
  METHODS
  After extracted liquid from Qianlietongyu treated the cultured prostatic smooth muscle cells, the anti proliferative and apoptotic indices were assessed by MTT assy and terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) respectively.
  
  
  RESULTS
  There was a significant dose-effect relationship between the concentration of extracted liquid from Qianlietongyu and the antiproliferative index on prostatic smooth muscle cells in vitro (P < 0.01), but there was no markedly difference in the apoptosis index between the group of extracted liquid from Qianlietongyu and control group ( P > 0.05).
  
  
  CONCLUSIONS
  Extracted liquid from Qianlietongyu may show significant antiproliferative effect on prostatic smooth muscle cells in vitro, without inducing apoptosis.
authors.affiliation: Department of Andrology, Zhuhai Branchi Guangdong Provincial Hospital of TCM, Zhuhai, Guangdong 519015, China. ctwman@163.com
authors.forename: Tong-Wen
authors.initials: TW
authors.lastname: Chne
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Deng
authors.forename: Jian-Zhong
authors.initials: JZ
authors.lastname: Liu
authors.forename: Rong-Hui
authors.initials: RH
authors.lastname: Chne
authors.forename: He-Liang
authors.initials: HL
authors.lastname: Chen
authors.forename: Wen-Feng
authors.initials: WF
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Zhou
authors.forename: Jin-Mei
authors.initials: JM
authors.lastname: Liu
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Xiong
mesh_terms: D017209:Apoptosis; D049109:Cell Proliferation; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D032389:Myocytes, Smooth Muscle / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D011467:Prostate / Q000166:cytology* / Q000187:drug effects*
chemical_list: D010936:Plant Extracts