title: Outcome of surgical management of the bladder in advanced colorectal cancer.
abstract: BACKGROUND
  To evaluate morbidity, mortality, and long-term survival in patients undergoing partial or total cystectomy during en bloc resection for locally advanced colorectal cancer.
  
  
  METHODS
  This study retrospectively evaluated the outcome of combined bladder resection for colorectal cancer in our department.
  
  
  RESULTS
  Patients (n=33) with colorectal tumors adherent to the bladder were followed. Overall morbidity was 11/33 (33.3%). Histological staging demonstrated inflammatory adhesion in 54.5% (18/33) and invasion in 45.6% (15/33). Morbidity was significantly higher in those that had undergone total cystectomy than in those that had undergone partial cystectomy (4/5 vs 7/28, P=0.033). The local recurrence has no difference the between total cystectomy group and the partial cystectomy group (1/5 vs 8/28, P=1.000). Overall 5-year survival rate was 39.4% (13/33). Mean survival time was 46.6875 month. There was no difference in 5-year survival between patients with inflammatory adhesion vs those with tumorous infiltration between colorectal tumor and bladder (P=0.7389).
  
  
  CONCLUSIONS
  Survival after surgery for colorectal cancer is not influenced by the need to excise part or all of the urinary bladder in case it is contiguous to a colorectal tumor. Experienced surgeons in urology and colon and rectal surgery should be left to decide on the surgical options to be employed.
authors.affiliation: Department of Coloproctological Surgery of The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Zhuang Autonomous Region, People's Republic of China. doctorgao0771@hotmail.com
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
authors.forename: Yun-fei
authors.initials: YF
authors.lastname: Cao
authors.forename: Li-sheng
authors.initials: LS
authors.lastname: Chen
authors.forename: Sen
authors.initials: S
authors.lastname: Zhang
authors.forename: Zong-jiang
authors.initials: ZJ
authors.lastname: Tang
authors.forename: Jun-lin
authors.initials: JL
authors.lastname: Liang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015653:Cystectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000473:pathology* / Q000601:surgery