title: Poststroke depression: a biopsychosocial approach.
abstract: Poststroke depression (PSD) is a form of geriatric depression that is associated with various negative outcomes. This article reviews existing research concerning the etiology, treatment, and prevention of PSD with particular emphasis on the development of a biopsychosocial conceptualization of PSD etiology and treatment. Existing intervention trials are reviewed. A behavioral model of PSD treatment is presented based on a biopsychosocial understanding of PSD that highlights the potential utility of the lesion location hypothesis in the early poststroke period and the behavioral and social changes that may be linked to depression in the postacute period after stroke.
authors.affiliation: Psychological and Brain Sciences, University of Louisville, 317 Life Sciences Building, Louisville, KY 40292, USA. b.mast@louisville.edu
authors.forename: Benjamin T
authors.initials: BT
authors.lastname: Mast
authors.forename: Sarah
authors.initials: S
authors.lastname: Vedrody
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D000928:Antidepressive Agents / Q000627:therapeutic use*; D017028:Caregivers / Q000523:psychology; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D017281:Cost of Illness; D003866:Depressive Disorder / Q000175:diagnosis / Q000517:prevention & control / Q000523:psychology / Q000534:rehabilitation*; D006801:Humans; D009788:Occupational Therapy; D010348:Patient Care Team; D012803:Sick Role; D012919:Social Behavior; D020521:Stroke / Q000150:complications* / Q000523:psychology; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D000697:Central Nervous System Stimulants