Determination of fludioxonil and famoxadone in processed fruits and vegetables by liquid chromatography/electrospray tandem mass spectrometry.
The feasibility of using liquid chromatography/ electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS) for determining 2 fungicides (fludioxonil and famoxadone) in tomato pulp, pear purée, and concentrated lemon juice has been evaluated. A miniaturized extraction-partition procedure requiring small amounts of nonchlorinated solvents was used. The extracts (5 microL) were analyzed by LC/ESI-MS/MS without previous cleanup. Chromatographic determination was performed using a C18 column with isocratic elution. Four MS/MS transitions of precursor ions were monitored simultaneously (2 for each pesticide) by means of negative ESI. Mean recoveries from samples at fortification levels of 0.002-0.020 mg/kg (fludioxonil) and 0.010-0.100 mg/kg (famoxadone) ranged from 77.1 to 96.5%, with associated relative standard deviations between 4.2 and 11.5%.
Sannino
Anna
A
Stazione Sperimentale per l'Industria delle Conserve Alimentari, Viale F.Tanara 31/A 43100 Parma, Italy. anna.sannino@ssica.it
Bandini
Mirella
M
D001628:Beverages; D002138:Calibration; D002623:Chemistry Techniques, Analytical / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods*; D002957:Citrus; D004149:Dioxoles / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D005511:Food Handling; D005519:Food Preservation; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D018551:Solanum lycopersicum; D013058:Mass Spectrometry / Q000379:methods; D008689:Methacrylates / Q000032:analysis; D008956:Models, Chemical; D010080:Oxazoles / Q000032:analysis*; D010573:Pesticide Residues; D010575:Pesticides / Q000032:analysis; D011758:Pyrroles / Q000032:analysis*; D031989:Pyrus; D015203:Reproducibility of Results; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D000073739:Strobilurins; D013997:Time Factors
D004149:Dioxoles; D008689:Methacrylates; D010080:Oxazoles; D010573:Pesticide Residues; D010575:Pesticides; D011758:Pyrroles; D012997:Solvents; D000073739:Strobilurins; C108339:fludioxonil; C401929:famoxadone