Increased Tei index suggests absence of adequate coronary reperfusion in patients with first anteroseptal acute myocardial infarction.
BACKGROUND
The estimation of coronary reperfusion in acute myocardial infarction (AMI) is important. The left ventricular (LV) Tei index is a noninvasive and sensitive parameter expressing overall LV function. We hypothesized that patients without good coronary reperfusion have worse LV function with a higher or worse Tei index compared to those with good reperfusion.


RESULTS
In 85 patients with first anteroseptal AMI, without other cardiac lesions such as prior myocardial infarction, LV hypertrophy or valvular disease, the Tei index was measured using Doppler echocardiography immediately after patients' arrival to the hospital, and the Thrombolysis in Myocardial Infarction (TIMI) grade was evaluated through subsequent coronary angiography. The Tei index was significantly greater in patients who did not have TIMI score of 3 compared to those with a TIMI of 3 (0.60+/-0.13 vs 0.46+/-0.06, p<0.0001). A Tei index >0.50 as the criteria for the absence of TIMI 3 had the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 75, 86, 94, 54 and 78%, respectively.


CONCLUSIONS
An increased Tei index suggests the absence of adequate coronary reperfusion in patients with first anterior AMI without other lesion.
Kuwahara
Eiji
E
Department of Cardiovascular Medicine, Kagoshima University School of Medicine, Japan.
Otsuji
Yutaka
Y
Takasaki
Kunitsugu
K
Yuasa
Toshinori
T
Kumanohoso
Toshiro
T
Nakashima
Hitoshi
H
Toyonaga
Koichi
K
Yoshifuku
Shiro
S
Miyata
Masaaki
M
Hamasaki
Shuichi
S
Lee
Souki
S
Kisanuki
Akira
A
Minagoe
Shinichi
S
Tei
Chuwa
C
D000208:Acute Disease; D000368:Aged; D017023:Coronary Angiography; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000473:pathology / Q000502:physiology*; D015150:Echocardiography, Doppler; D005260:Female; D006334:Heart Function Tests; D006346:Heart Septum / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology*; D015425:Myocardial Reperfusion; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*