[The influence of cigarette smoking on sperm quality of male smokers and nonsmokers in infertile couples].
In this prospective study we investigated different semen parameters of infertile smokers with a history of cigarette smoking. 27 infertile men who smoked cigarettes, 79 infertile men who were nonsmokers and 82 healthy nonsmoking donors were evaluated. Smokers had significantly less spermatozoa with motility grade B (9.37% versus 11.9%, p<0.05), decreased results of hypoosmotic swelling test (46.39% versus 52.11%, p<0.05) than nonsmokers infertile men. The concentration of leukocytes in semen was significantly higher in smokers (0.26 mln/ml versus 0.11 mln/ml, p>0.05), which can also suggests oxidative imbalance in the ejaculates of these men. No differences were found in the assessment of sperm concentration, motility grade A, C, D, percentage normal forms and different sperm defects, induced acrosomal reaction and acidic aniline blue staining test between these two groups (p>0.05). Our data demonstrate that cigarette smoking alters semen quality which could worsen fertilizing capability in infertile men.
Taszarek-H
Grazyna
G
Klinika Niepłodności i Erndokrynologii Rozrodu, Katedry Ginekologii i Połoznictwa, Akademii Medycznej w Poznaniu.
Depa-Martynów
Magdalena
M
Derwich
Krzysztof
K
Pawelczyk
Leszek
L
Jedrzejczak
Piotr
P
D000328:Adult; D005191:Family Characteristics; D006801:Humans; D007248:Infertility, Male; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000009:adverse effects*; D011446:Prospective Studies; D012907:Smoking / Q000009:adverse effects*; D013075:Sperm Capacitation / Q000187:drug effects*
D009538:Nicotine