Study on the reactions of azo compounds with acyl halides mediated by Sm/TiCl4.
Amides can be obtained in good to excellent yield by Sm/TiCl(4) mediated reductive cleavage of N=N bond in azo compounds and successive acylation in one pot. It offers an alternative method for the synthesis of amides from very simple starting materials directly.
Li
Xue
X
Department of Chemistry, Zhejiang University, Hangzhou 310028, China.
Zhang
Yong-min
YM
D001391:Azo Compounds / Q000737:chemistry*; D017606:Chlorine Compounds / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006219:Halogens / Q000737:chemistry*; D012493:Samarium / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*
D001391:Azo Compounds; D017606:Chlorine Compounds; D006219:Halogens; D012493:Samarium; D014025:Titanium