title: Severe community-acquired pneumonia due to Legionella pneumophila Serogroup 6.
abstract: Legionella pneumophila is a common cause of sporadic community-acquired pneumonia, but culture-proven legionellosis is rarely diagnosed. There is no laboratory test for Legionnaires' disease that can detect all patients with the disease. Culture is the standard diagnostic method and should be initiated as soon as possible in suspected cases. We describe a rare case of community-acquired pneumonia caused by L. pneumophila serogroup 6. A 77-year-old man was admitted to a tertiary care hospital because of high fever, productive cough, and progressive dyspnea. Chest radiography showed bilateral pneumonia, which led to respiratory failure necessitating mechanical ventilatory support. Despite antibiotic therapy, his condition continued to deteriorate and acute renal failure also developed. Urine was negative for L. pneumophila. Culture of the sputum yielded L. pneumophila serogroup 6, although there was no elevation of the serum antibody titer. Pneumonia resolved gradually and he was extubated after treatment with levofloxacin followed by erythromycin. L. pneumophila other than serogroup 1 should be included in the differential diagnosis of patients with suspected atypical community-acquired pneumonia.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. kuanyu@ha.mc.ntu.edu.tw
authors.forename: Chung-Yu
authors.initials: CY
authors.lastname: Chen
authors.forename: Kuan-Yu
authors.initials: KY
authors.lastname: Chen
authors.forename: Po-Ren
authors.initials: PR
authors.lastname: Hsueh
authors.forename: Pan-Chyr
authors.initials: PC
authors.lastname: Yang
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D012703:Serotyping
chemical_list: D000900:Anti-Bacterial Agents