[Effect of extracted liquid from qianlietongyu on the proliferation and apoptosis on prostatic smooth muscle cells in vitro].
OBJECTIVE
To explore the effect of extracted liquid from Qianlietongyu on the proliferation or apoptosis on prostatic smooth muscle cells in vitro.


METHODS
After extracted liquid from Qianlietongyu treated the cultured prostatic smooth muscle cells, the anti proliferative and apoptotic indices were assessed by MTT assy and terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) respectively.


RESULTS
There was a significant dose-effect relationship between the concentration of extracted liquid from Qianlietongyu and the antiproliferative index on prostatic smooth muscle cells in vitro (P < 0.01), but there was no markedly difference in the apoptosis index between the group of extracted liquid from Qianlietongyu and control group ( P > 0.05).


CONCLUSIONS
Extracted liquid from Qianlietongyu may show significant antiproliferative effect on prostatic smooth muscle cells in vitro, without inducing apoptosis.
Chne
Tong-Wen
TW
Department of Andrology, Zhuhai Branchi Guangdong Provincial Hospital of TCM, Zhuhai, Guangdong 519015, China. ctwman@163.com
Deng
Chun-Hua
CH
Liu
Jian-Zhong
JZ
Chne
Rong-Hui
RH
Chen
He-Liang
HL
Wang
Wen-Feng
WF
Zhou
Hong
H
Liu
Jin-Mei
JM
Zhang
Xiao-Hong
XH
Xiong
Ying
Y
D017209:Apoptosis; D049109:Cell Proliferation; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D032389:Myocytes, Smooth Muscle / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D011467:Prostate / Q000166:cytology* / Q000187:drug effects*
D010936:Plant Extracts