Stem cells and the heart: ethics, organization and funding.
The application of stem cell biology to repair of the heart offers therapeutic potential. However, randomized, double-blind, controlled trials are required to clarify under what conditions it may be effective. The unprecedented nature of the discovery of a therapeutic role for autologous stem cells brings with it unprecedented challenges in clinical application of basic biology, ethics, funding and organization. It is suggested that the academic community should show leadership.
Martin
John F
JF
British Heart Foundation Laboratories, Centre for Cardiovascular Biology and Medicine, University College London, London, UK. john.martin@ucl.ac.uk
D002986:Clinical Trials as Topic; D006331:Heart Diseases / Q000628:therapy*; D006801:Humans; D044968:Regenerative Medicine / Q000191:economics / Q000941:ethics / Q000458:organization & administration; D012109:Research Support as Topic; D033581:Stem Cell Transplantation