title: The outlook for implants and endodontics: a review of the tissue engineering strategies to create replacement teeth for patients.
abstract: Ideally, root canal therapy involves the removal of diseased pulp tissues and permanent replacement with healthy pulp to revitalize teeth. Rather than placing implants, the ideal solution is to grow new replacement teeth. Success rates of implants and endodontic treatments can exceed 90%, which presents a formidable challenge to tissue engineering researchers to ensure that future dental treatments are even more successful. The purpose of this article is to explain how tissue engineering can be used to create replacement teeth. The science of tissue engineering has evolved from growing simple tissues in cell culture incubators to a multistep process. Although the problems of introducing tissue engineering therapies as part of routine dental treatments are substantial, the potential benefits are equally ground breaking.
authors.affiliation: College of Dental Medicine, Nova Southeastern University, 3200 South University Drive, Fort Lauderdale, FL 33328, USA. petemurr@nsu.nova.edu
authors.forename: Peter E
authors.initials: PE
authors.lastname: Murray
authors.forename: Franklin
authors.initials: F
authors.lastname: García-Godoy
mesh_terms: D040761:Biomimetic Materials / Q000627:therapeutic use; D003758:Dental Implantation, Endosseous / Q000295:instrumentation / Q000379:methods*; D003782:Dental Pulp / Q000166:cytology / Q000502:physiology; D003810:Dentinogenesis / Q000502:physiology*; D004708:Endodontics / Q000379:methods* / Q000639:trends; D005544:Forecasting; D006801:Humans; D009804:Odontoblasts / Q000502:physiology; D012038:Regeneration / Q000502:physiology*; D013234:Stem Cells / Q000502:physiology; D023822:Tissue Engineering / Q000295:instrumentation / Q000379:methods*; D014070:Tooth / Q000166:cytology / Q000502:physiology* / Q000601:surgery; D018677:Tooth Injuries / Q000628:therapy