title: Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas.
abstract: OBJECTIVE
  To compare the postoperative recovery of patients undergoing laparoscopic and minilaparotomic myomectomy.
  
  
  METHODS
  Randomized study (Canadian Task Force classification I).
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One hundred forty-eight women requiring surgical myomectomy.
  
  
  METHODS
  Myomectomy by minilaparotomy or laparoscopy.
  
  
  RESULTS
  Operation time was significantly lower in the minilaparotomy group (p < .001). When compared with minilaparotomy, laparoscopy was associated with a lower decline of hemoglobin concentration (p <.001), a reduced length of postoperative ileus (p < .001), and a shorter time to discharge (p <.001). Pain intensity at 6 hours after surgery was significantly lower in the laparoscopy group (p <.001); also, patients who underwent laparoscopy requested analgesics less frequently in the first 48 hours after the operation (p < .001). Patients included in the laparoscopy group were fully recuperated on postoperative day 15 more frequently than those included in the minilaparotomy group (p = .012). No complications were observed in the minilaparotomy group. There were two complications in the laparoscopy group (one laparoconversion caused by difficulties of hemostasis and one acute diffuse peritonitis caused by ileal perforation). Laparoscopic and minilaparotomic myomectomy cost, respectively, 2250 euros and 1975 euros.
  
  
  CONCLUSIONS
  When compared with minilaparotomic myomectomy, laparoscopic myomectomy may offer the benefits of lower postoperative analgesic use and faster postoperative recovery.
authors.affiliation: Department of Obstetrics and Gynecology, San Martino Hospital and University of Genoa, Largo R. Benzi 10, 16132, Genoa, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Alessandri
authors.forename: Davide
authors.initials: D
authors.lastname: Lijoi
authors.forename: Emanuela
authors.initials: E
authors.lastname: Mistrangelo
authors.forename: Simone
authors.initials: S
authors.lastname: Ferrero
authors.forename: Nicola
authors.initials: N
authors.lastname: Ragni
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D010535:Laparoscopy / Q000379:methods*; D007813:Laparotomy / Q000379:methods*; D007889:Leiomyoma / Q000175:diagnosis* / Q000601:surgery*; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011336:Probability; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000601:surgery*