Hypopituitarism and growth hormone deficiency in adult subjects after traumatic brain injury: who and when to test.
Traumatic brain injury (TBI) was traditionally considered an infrequent cause of hypopituitarism. However recent reports strongly suggest that TBI-mediated pituitary hormones deficiency may well be more frequent than previously thought. As the prevalence of hypopituitarism is not dependent on the severity of the trauma and considering the high number of TBI events in all industrialized countries a screening procedure for detecting hormone deficiencies in all TBI patients is not possible. In the present work a suggestion for screening a subgroup of TBI patients is discussed in order to increase the effectiveness of the whole procedure.
Lorenzo
Monica
M
Department of Medicine, Endocrine Section, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela University, Santiago de Compostela, Spain.
Peino
Roberto
R
Castro
Ana I
AI
Lage
Mary
M
Popovic
Vera
V
Dieguez
Carlos
C
Casanueva
Felipe F
FF
D001930:Brain Injuries / Q000150:complications*; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D008403:Mass Screening; D015995:Prevalence; D012720:Severity of Illness Index; D013997:Time Factors
D013006:Growth Hormone