title: Advanced neurologic monitoring for cardiac surgery.
abstract: Cardiac surgery (CS) with cardiopulmonary bypass (CPB) is currently the most common surgery in the United States. Understanding, avoiding, and preventing postoperative complications, including neurologic deficits following CS, represents a great public and economic benefit for society, especially considering our aging population. There is a critical need to identify new strategies that will prevent harmful events during and after CS. At present, experience with neurophysiologic techniques includes the ability to measure cerebral blood flow velocity/emboli and regional cerebral venous oxygen saturation by transcranial Doppler ultrasound, and by near-infrared spectroscopy, respectively. Continuous monitoring of these variables along with systemic hemodynamics will provide a better understanding of mechanisms of brain and other organ injury during CPB. Neuroprotective interventions based on multimodality neurologic monitoring would ideally eliminate postoperative complications and improve patient outcomes.
authors.affiliation: Sentient Medical Systems, Inc., 10151 York Road, Suite 120, Cockeysville, MD 21030, USA. arazumov@surgicalmonitoring.net
authors.forename: Alexander Y
authors.initials: AY
authors.lastname: Razumovsky
authors.forename: Lavern D
authors.initials: LD
authors.lastname: Gugino
authors.forename: Jeffrey H
authors.initials: JH
authors.lastname: Owen
mesh_terms: D050197:Atherosclerosis / Q000601:surgery*; D001783:Blood Flow Velocity; D001930:Brain Injuries / Q000209:etiology / Q000517:prevention & control*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D001026:Coronary Artery Bypass; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology / Q000517:prevention & control*; D016343:Monitoring, Intraoperative / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control*; D019265:Spectroscopy, Near-Infrared