Classification of AML by DNA-oligonucleotide microarrays.
Accurate diagnosis and classification of leukemias are the bases for the appropriate management of patients. The diagnostic accuracy and efficiency of present methods may be improved by the use of microarrays. The following chapter gives an overview of the method of gene expression profiling of leukemia samples, its laboratory procedure, and how to approach the analysis of the data.
Kohlmann
Alexander
A
Laboratory for Leukemia Diagnostics, Department of Internal Medicine III, Ludwig-Maximilians-University, Munich, Germany.
Kern
Wolfgang
W
Hiddemann
Wolfgang
W
Haferlach
Torsten
T
D018076:DNA, Complementary / Q000235:genetics; D004273:DNA, Neoplasm / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000145:classification* / Q000175:diagnosis / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D016133:Polymerase Chain Reaction / Q000379:methods; D012334:RNA, Neoplasm / Q000235:genetics / Q000302:isolation & purification; D015203:Reproducibility of Results
D018076:DNA, Complementary; D004273:DNA, Neoplasm; D012334:RNA, Neoplasm