title: Laparoscopic antireflux surgery: indications, preoperative evaluation, techniques, and outcomes.
abstract: OBJECTIVE
  During the past decade, the development of mini-invasive surgery has determined a resurgence in popularity of the antireflux surgery. The purpose of this study is to examine indications, preoperative evaluation, surgical techniques, and outcomes after mini-invasive surgery.
  
  
  METHODS
  From 1996 to 2000, 25 patients with gastroesophageal reflux disease associated to hiatal hernia underwent laparoscopic surgery. The indication for surgery was failure of long-term medical therapy. All patients had severe acid reflux on 24h-pH monitoring, endoscopic evidence of esophagitis, and defective lower esophageal sphincter. Nissen fundoplication was performed in 16 patients with normal esophageal body motility, and 270 degrees posterior fundoplication in 9 patients with low esophageal motility.
  
  
  RESULTS
  Mortality and conversion rate were 0. Mean operative time was 130 minutes and mean postoperative hospital stay 5 days. Twenty-four (96%) patients were completely cured of reflux symptoms off all medications. Transient, mild postoperative dysphagia occurred in 3 patients (12%). There was a significant improvement of the results in postoperative esophageal manometry and 24h-pH monitoring.
  
  
  CONCLUSIONS
  Despite the fact that few patients were treated by using laparoscopic approach, results are encouraging with less morbidity and great advantages for patients. Precise selection of patients and surgical techniques are essential.
authors.affiliation: Department of General, Oncological and Videoassisted Surgery, University of Naples Federico II, School of Medicine, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Benassai
authors.forename: M
authors.initials: M
authors.lastname: Mastrorilli
authors.forename: G
authors.initials: G
authors.lastname: Quarto
authors.forename: G
authors.initials: G
authors.lastname: Galloro
authors.forename: A
authors.initials: A
authors.lastname: Cantelmo
authors.forename: T
authors.initials: T
authors.lastname: Esposito
mesh_terms: D000328:Adult; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D016896:Treatment Outcome