Study on small gap sleeve bridging peripheral nerve injury.
Epineurium or perineurium neurorrhaphy to recover the nerve continuity was the choice of peripheral nerve mutilation. The nerve selective regeneration theory was put forth by Cajal et al. As this theory was gradually accepted, many researchers had focused on it and its possible application. Our labs had centered on the small gap sleeve bridging fields for about 30 years, using autogeneic vein, artery and biogradable chitin conduits. Our goal was to improve the nerve regeneration effect by means of nerve selective regeneration theory and degradable biomaterials. This serial experiment was to confirm the possibilities of using conduit small gap sleeve bridging to substitute the traditional epineurium neurorrhaphy.
Jiang
Baoguo
B
Department of Trauma and Orthopeadics, People's Hospital, Peking University, Beijing, China. jiangbaoguo@vip.sina.com
Zhang
Peixun
P
Zhang
Dianying
D
Fu
Zhongguo
Z
Yin
Xiaofeng
X
Zhang
Hongbo
H
D000818:Animals; D001672:Biocompatible Materials; D008422:Materials Testing / Q000379:methods; D019736:Prostheses and Implants; D051381:Rats; D017207:Rats, Sprague-Dawley; D012038:Regeneration; D012584:Sciatic Nerve / Q000473:pathology; D020196:Trauma, Nervous System / Q000628:therapy*
D001672:Biocompatible Materials