title: [Mycotic keratitis and endophthalmitis caused by unusual fungi: Lasiodiplodia theobromae].
abstract: We report a case of endophthalmitis caused by the fungus Lasiodiplodia theobromae. A 68-year-old man was referred to the hospital for right ocular pain since experiencing right ocular branch trauma 2 weeks before. The best-corrected acuity was limited to hand motion. Slit-lamp examination showed a large corneal abscess and an anterior chamber reaction. The patient underwent systemic and local antibiotic therapy, and corneal scraping for microbiological diagnosis. Sabouraud-chloramphenicol-gentamicin agar disclosed filamentous fungus, which was treated with oral itraconazole and topic amphotericin B. Molecular biology revealed Lasiodiplodia theobromae. Despite antimycotic drugs, severe panophthalmia occurred very quickly and led to evisceration. This case report describes Lasiodiplodia theobromae as the cause of keratomycosis and discusses risk factors and clinical features of fungal keratitis in order to improve prognosis by earlier treatment.
authors.affiliation: Service d'Ophtalmologie, Centre Hospitalier Universitaire de Fort de France, Hôpital Pierre Zobda-Quitman, Fort de France. angelique.donnio-cordoba@wanadoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Donnio
authors.forename: N
authors.initials: N
authors.lastname: Desbois
authors.forename: P
authors.initials: P
authors.lastname: Boiron
authors.forename: R
authors.initials: R
authors.lastname: Théodose
authors.forename: D
authors.initials: D
authors.lastname: Mouniee
authors.forename: F
authors.initials: F
authors.lastname: Thoumazet
authors.forename: H
authors.initials: H
authors.lastname: Merle
mesh_terms: D000368:Aged; D001203:Ascomycota; D009877:Endophthalmitis / Q000382:microbiology*; D006801:Humans; D007634:Keratitis / Q000382:microbiology*; D008297:Male; D009181:Mycoses