title: On the application of "equation-free modelling" to neural systems.
abstract: "Equation-free modelling" is a recently-developed technique for bridging the gap between detailed, microscopic descriptions of systems and macroscopic descriptions of their collective behaviour. It uses short, repeated bursts of simulation of the microscopic dynamics to analyse the effective macroscopic equations, even though such equations are not directly available for evaluation. This paper demonstrates these techniques on a variety of networks of model neurons, and discusses the advantages and limitations of such an approach. New results include an understanding of the effects of including gap junctions in a model capable of sustaining spatially localised "bumps" of activity, and an investigation of a network of coupled bursting neurons.
authors.affiliation: Institute of Information and Mathematical Sciences, Massey University, Private Bag 102-904, North Shore Mail Centre, Auckland, New Zealand. c.r.laing@massey.ac.nz
authors.forename: Carlo R
authors.initials: CR
authors.lastname: Laing
mesh_terms: D000818:Animals; D005246:Feedback / Q000502:physiology; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009420:Nervous System; D009433:Neural Inhibition / Q000502:physiology; D016571:Neural Networks, Computer; D009474:Neurons / Q000502:physiology*; D017711:Nonlinear Dynamics; D011336:Probability