Discovery of an imidazo-phenanthridine synthon produced in a 'five-step one-pot reaction' leading to a new family of heterocycles with novel physical properties.
A new class of heterocyclic aromatic cation with novel physical properties has been constructed by an unprecedented reaction pathway that proceeds via five spontaneous steps to yield a 'synthon' that can be further derivatised by a final nucleophilic substitution step.
Parenty
Alexis D C
AD
WestCHEM, University of Glasgow, Department of Chemistry, Glasgow, UK G12 8QQ.
Guthrie
Kevin M
KM
Song
Yu-Fei
YF
Smith
Louise V
LV
Burkholder
Eric
E
Cronin
Leroy
L
D004247:DNA / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D010617:Phenanthridines / Q000138:chemical synthesis / Q000737:chemistry; D013329:Structure-Activity Relationship
D006571:Heterocyclic Compounds; D007093:Imidazoles; D010617:Phenanthridines; D004247:DNA