title: Multisegment and halfscan reconstruction of 16-slice computed tomography for assessment of regional and global left ventricular myocardial function.
abstract: OBJECTIVE
  We sought to prospectively compare multisegment and halfscan reconstruction of 16-slice computed tomography (CT) for the assessment of regional and global left ventricular myocardial function with magnetic resonance imaging (MRI) as the reference standard.
  
  
  METHODS
  Forty-two patients underwent CT with 16 x 0.5-mm detector collimation. Electrocardiogram-gated reconstructions were generated with multisegment reconstruction (using up to 4 segments correlated with the raw data of up to 4 heartbeats) and standard halfscan reconstruction. Steady-state free-precession cine MRI was acquired within 24 hours.
  
  
  RESULTS
  More normal myocardial segments were identified correctly with multisegment (95%, 620/656) compared with halfscan reconstruction (88%, 582/656) of CT (P < 0.001). Also, the accuracy (92% [657/714] vs. 87% [620/714]) and rate of nondiagnostic segments (0% vs. 5% [33/714]) were significantly better when using multisegment reconstruction (P < 0.001). The image quality with multisegment reconstruction was significantly superior to that achieved with halfscan reconstruction (P < 0.001). In the assessment of global left ventricular function, multisegment and halfscan reconstruction of CT showed high correlations for all parameters with MRI, whereas Bland-Altman analysis revealed smaller limits of agreement for assessment of myocardial mass with multisegment reconstruction (P = 0.025), but no significant differences between both reconstruction techniques in the measurement of left ventricular volumes as compared with MRI.
  
  
  CONCLUSIONS
  Multisegment reconstruction of 16-detector row CT improves image quality and assessment of regional wall motion compared with standard halfscan reconstruction.
authors.affiliation: Department of Radiology, Freie Universität and Humboldt-Universität zu Berlin, Germany. marc.dewey@charite.de
authors.forename: Marc
authors.initials: M
authors.lastname: Dewey
authors.forename: Mira
authors.initials: M
authors.lastname: Müller
authors.forename: Florian
authors.initials: F
authors.lastname: Teige
authors.forename: Dirk
authors.initials: D
authors.lastname: Schnapauff
authors.forename: Tania
authors.initials: T
authors.lastname: Schink
authors.forename: Bernd
authors.initials: B
authors.lastname: Hamm
authors.forename: Alexander
authors.initials: A
authors.lastname: Lembcke
mesh_terms: D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000503:physiopathology*