title: Artificial crystalline lens.
abstract: If presbyopia is caused by hardening of the crystalline lens, replacing it with a material with mechanical properties similar to the young crystalline lens should restore accommodative ability. Such a silicone material has been developed. Refilling the capsular bag with this material results in 3 to 5 D of accommodation in primates in response to pilocarpine.
authors.affiliation: Pharmacia, AMO Groningen BV, Van Swietenlaan 5, Groningen NL-9728 NX, Netherlands. sverker.norrby@amo-inc.com
authors.forename: Sverker
authors.initials: S
authors.lastname: Norrby
authors.forename: Steven
authors.initials: S
authors.lastname: Koopmans
authors.forename: Thom
authors.initials: T
authors.lastname: Terwee
mesh_terms: D000818:Animals; D001187:Artificial Organs; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000295:instrumentation*; D007908:Lens, Crystalline; D007910:Lenses, Intraocular; D011474:Prosthesis Design; D012029:Refraction, Ocular; D054140:Refractive Surgical Procedures