title: Identification of human H1N2 and human-swine reassortant H1N2 and H1N1 influenza A viruses among pigs in Ontario, Canada (2003 to 2005).
abstract: Since 2003, three novel genotypes of H1 influenza viruses have been recovered from Canadian pigs, including a wholly human H1N2 virus and human-swine reassortants. These isolates demonstrate that human-lineage H1N2 viruses are infectious for pigs and that viruses with a human PB1/swine PA/swine PB2 polymerase complex can replicate in pigs.
authors.affiliation: Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin--Madison, 2015 Linden Dr., Madison, WI 53706, USA.
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Karasin
authors.forename: Suzanne
authors.initials: S
authors.lastname: Carman
authors.forename: Christopher W
authors.initials: CW
authors.lastname: Olsen
mesh_terms: D000818:Animals; D016679:Genome, Viral; D005838:Genotype; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics* / Q000302:isolation & purification*; D009980:Influenza A virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D009864:Ontario; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D013045:Species Specificity; D034421:Sus scrofa / Q000821:virology*
chemical_list: D012367:RNA, Viral