Vogt-Koyanagi-Harada syndrome with intracranial meningioma: an as yet unreported association.
METHODS
We document a previously unreported association of Vogt-Koyanagi-Harada (VKH) syndrome with intracranial meningioma. A female patient with diminished vision, exudative retinal detachment, and headache was diagnosed with VKH syndrome, more precisely a Harada form of disease with intracranial meningioma, on the basis of exudative retinal detachment, typical fundus fluorescein findings, and magnetic resonance imaging. With intravenous steroid therapy, visual acuity improved and the detachment settled within a week. At 3 months, the detachment recurred but improved after retreatment. At 1 year, the tumour was unchanged in size.


CONCLUSIONS
VKH syndrome may be associated with intracranial meningioma that may affect the patient's overall morbidity or mortality.
Kumar
Atul
A
Centre for Ophthalmic Sciences, All India Institute of Medical Science, New Delhi, India. akum66mm@del6.vsnl.net.in
Chhabra
Manpreet S
MS
Prakash
Gunjan
G
Kulkarni
Amol D
AD
D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006261:Headache / Q000175:diagnosis; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D008579:Meningioma / Q000150:complications* / Q000000981:diagnostic imaging; D012163:Retinal Detachment / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014786:Vision Disorders / Q000175:diagnosis
D005938:Glucocorticoids