Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
Zhu
Xiongwei
X
Institute of Pathology, Case Western Reserve University, OH 44106, USA.
Lee
Hyoung-Gon
HG
Moreira
Paula I
PI
Smith
Mark A
MA
Perry
George
G
D000375:Aging / Q000235:genetics / Q000378:metabolism*; D000544:Alzheimer Disease / Q000235:genetics*; D000818:Animals; D006801:Humans; D015227:Lipid Peroxidation; D008565:Membrane Proteins / Q000235:genetics*; D051379:Mice; D008822:Mice, Transgenic; D009154:Mutation; D053764:Presenilin-1; D017382:Reactive Oxygen Species / Q000378:metabolism*
D008565:Membrane Proteins; C508853:PSEN1 protein, human; D053764:Presenilin-1; D017382:Reactive Oxygen Species