title: Trends in outpatient prescription drug use and related costs in the US: 1998-2003.
abstract: OBJECTIVE
  To present a brief synopsis of trends in the number of prescriptions and retail costs of outpatient drugs dispensed in the US between 1998 and 2003.
  
  
  METHODS
  Data were extracted from IMS Health, the National Prescription Audit Plus and the National Disease and Therapeutic Index databases.
  
  
  RESULTS
  In 1998, 2.7 billion outpatient prescriptions were dispensed versus 3.6 billion in 2003. This equates to a 33.3% increase over the 6-year period. Of the top 20 most dispensed drugs by volume, 40% were launched in the 1990s or 2000s. Retail costs for the total market of dispensed outpatient prescription drugs were 96.1 billion US dollars in 1998 and 196 billion US dollars in 2003, a 104% increase. Of the top 20 most dispensed drugs by retail cost, all were tradename drugs and were launched in the 1990s or 2000s.
  
  
  CONCLUSIONS
  These data indicate a large increase in the US over a short time period in dispensed outpatient prescriptions and their associated retail costs.
authors.affiliation: Division of Drug Risk Evaluation, Food and Drug Administration, Rockville, Maryland, USA.
authors.forename: Diane K
authors.initials: DK
authors.lastname: Wysowski
authors.forename: Laura A
authors.initials: LA
authors.lastname: Governale
authors.forename: Joslyn
authors.initials: J
authors.lastname: Swann
mesh_terms: D016208:Databases, Factual; D016527:Drug Costs; D011307:Drug Prescriptions / Q000191:economics* / Q000706:statistics & numerical data; D010045:Outpatients / Q000706:statistics & numerical data*; D014481:United States