Selenium species bioaccessibility in enriched radish (Raphanus sativus): a potential dietary source of selenium.
An in vitro gastrointestinal method was employed to predict the potential bioavailability of selenium and its species from radish, belonging to the Brassicaceae family, grown in hydroponics media in the presence of inorganic selenium, such as Na2SeO3 and Na2SeO4. A low transformation of Se into organic forms was observed in radish plants grown in Se(VI)-enriched culture media. On the contrary, in those plants exposed to selenite, >95% of the total selenium was found as selenocystine (SeCys2), selenomethionine (SeMet), and Se-methylselenocysteine (SeMetSeCys). The concentrations of these species in fresh samples remained almost unaltered after a simulated gastrointestinal digestion. Therefore, a high selenium content of Se-methylselenocysteine (65%), previously reported as a cancer chemopreventive species, remained in the potentially bioabsorbable fraction. As these plants usually undergo a short development cycle, these results suggest that radish enriched in selenite could be a good choice as an organoselenium supplement for the human diet and animal feed.
Departamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, 28040 Madrid Spain.
Zoyne
Z
Pedrero
Yolanda
Y
Madrid
Carmen
C
Cámara
D001682:Biological Availability; D004063:Digestion; D018517:Plant Roots / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism; D031224:Raphanus / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism*; D064586:Selenic Acid; D012643:Selenium / Q000008:administration & dosage / Q000493:pharmacokinetics*; D018036:Selenium Compounds / Q000378:metabolism; D018038:Sodium Selenite / Q000378:metabolism
D018036:Selenium Compounds; D012643:Selenium; D018038:Sodium Selenite; D064586:Selenic Acid