Effects of cold water immersion on edema formation after blunt injury to the hind limbs of rats.
OBJECTIVE
Despite the long history of using cryotherapy to control edema, we found no randomized, controlled studies providing evidence to substantiate this common clinical practice. The purpose of this study was to determine whether cold water immersion affects edema formation following blunt injuries in rats.


METHODS
The feet of 16 rats were traumatized after hind limb volumes were determined. Four 30-minute treatments of cold water immersion (12.8 degrees C to 15.6 degrees C, 55 degrees F to 60 degrees F), interspersed with four 30-minute rest periods, began immediately after trauma to one randomly selected hind limb of each rat. The limb remained in a dependent position during all treatments, rest periods, and volumetric measurements.


METHODS
Sixteen anesthetized Zucker Lean rats were used in the study.


METHODS
Limb volumes were measured after each treatment and rest period for a total of 4 hours.


RESULTS
The volume of treated limbs was significantly smaller (p < .05) than the volume of untreated limbs after the first treatment and remained smaller throughout the experiment.


CONCLUSIONS
Immersing rat limbs in 12.8 degrees C to 15.6 degrees C (55 degrees F to60 degrees F) water immediately after blunt injury was effective in curbing edema formation.
Dolan
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Michael G. Dolan is Associate Professor and Athletic Trainer at Department of Sports Medicine and Exercise Sciences, Canisius College, Buffalo, NY.
Thornton
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Fish
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Mendel
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