Does thrombolysis benefit patients with lacunar syndrome?
The efficacy of thrombolysis in clinical stroke subtypes is unclear. We compared the benefit of intravenous rt-PA in 11 patients with lacunar syndrome with that in 33 patients with a non-lacunar syndrome. Patients were matched by NIHSS score and time to treatment. Although no statistically significant differences were detected in outcome, the benefit was greater in the non- lacunar syndrome group.
Cocho
Dolores
D
Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain. dcocho@hsp.santpau.es
Belvís
Roberto
R
Martí-Fàbregas
Joan
J
Bravo
Yolanda
Y
Aleu
Aitziber
A
Pagonabarraga
Javier
J
Molina-Porcel
Laura
L
Díaz-Manera
Jorge
J
San Roman
Luis
L
Martínez-Lage
María
M
Martínez
Alejandro
A
Moreno
Mireia
M
Martí-Vilalta
Josep-Lluis
JL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000175:diagnosis / Q000188:drug therapy*; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use; D012189:Retrospective Studies; D013577:Syndrome; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D016896:Treatment Outcome
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator