Levels of protein C and activated protein C: what do they mean?
Acute pancreatitis is a local inflammatory process that leads to a systemic inflammatory response in the majority of cases, and sometimes leads to multiple organ failure. It is obvious that coagulation and especially the protein C system are involved in this disease. The present commentary is related to a study in patients with pancreatitis with and without multiple organ failure in which protein C and activated protein C levels were studied. The protein C system and other studies analyzing (activated) protein C levels are discussed.
Hazelzet
Jan A
JA
Erasmus MC, Sophia Children's Hospital, Pediatric Intensive Care Unit, Rotterdam, The Netherlands. j.a.hazelzet@erasmusmc.nl
D006801:Humans; D009102:Multiple Organ Failure / Q000097:blood / Q000175:diagnosis; D010195:Pancreatitis / Q000097:blood / Q000175:diagnosis; D011486:Protein C / Q000378:metabolism*
D011486:Protein C