Decreased growth capacity of passaged gross virus-induced mouse lymphomas after incubation with antithymocytic sera.
AKR or C3H/HeJ transplanted mouse lymphomas, originally induced by Gross virus, could be neutralized by in vitro incubation with an immunosuppressive rabbit anti-mouse thymus cell serum. Neutralization was measured by significantly increased latent periods or decreased incidence (at a minimum of 90 days post-transfer) of lymphoma in syngeneic recipients of lymphoma cells incubated with antithymocytic serum when compared with syngeneic recipients of lymphoma cells incubated with normal rabbit serum.
Vredevoe
D L
DL
Laboratory of Nuclear Medicine and Radiation Biology, School of Nursing, University of California, Los Angeles, California 90024.
Hays
E F
EF