Retention and removal of a new viscous dispersive ophthalmic viscosurgical device during cataract surgery in animal eyes.
OBJECTIVE
To assess the retention and removal properties of a new viscous dispersive ophthalmic viscosurgical device (OVD), DisCoVisc, in comparison with those of cohesive (Provisc), dispersive (Viscoat), and viscoadaptive (Healon5) OVDs.


METHODS
In 20 porcine eyes, cataract surgery was simulated using one of the four OVDs which were stained with fluorescein for better visualisation. Three parameters were measured. Firstly, the presence/absence of OVDs in the chamber at the completion of phacoemulsification was recorded. Secondly, the time until the OVDs were completely removed from the anterior chamber using the phaco needle was measured. Thirdly, after intraocular lens (IOL) implantation, the time needed to completely remove the OVDs from the chamber with irrigation/aspiration tip was recorded.


RESULTS
At the completion of phacoemulsification, the OVDs retained in 0% (0/5) for Provisc, 80% (4/5) for Healon5, 100% (5/5) for DisCoVisc, and 100% (5/5) for Viscoat. The retention of OVDs during phacoemulsification was greatest with Viscoat followed by, in descending order, DisCoVisc, Healon5, and Provisc. The removal of OVDs after IOL implantation took longest with Viscoat followed by Healon5, DisCoVisc, and Provisc.


CONCLUSIONS
The viscous dispersive DisCoVisc showed excellent retention during phacoemulsification, while its removal after IOL implantation was very easy. When compared with the viscoadaptive Healon5, DisCoVisc was retained better in the chamber and was easier to remove. These features of DisCoVisc should be highly advantageous when considering covering the entire cataract surgery procedure with a single OVD.
Oshika
T
T
Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575 Japan. toshika@md.tsukuba.ac.jp
Okamoto
F
F
Kaji
Y
Y
Hiraoka
T
T
Kiuchi
T
T
Sato
M
M
Kawana
K
K
D000818:Animals; D000867:Anterior Chamber; D002807:Chondroitin / Q000737:chemistry*; D002809:Chondroitin Sulfates; D020878:Device Removal; D004338:Drug Combinations; D004548:Elasticity; D006820:Hyaluronic Acid / Q000737:chemistry*; D007430:Intraoperative Care / Q000379:methods*; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification / Q000295:instrumentation*; D013552:Swine; D007507:Therapeutic Irrigation; D014783:Viscosity
D004338:Drug Combinations; C501944:chondroitin sulfate, sodium hyaluronate drug combination; D006820:Hyaluronic Acid; D002807:Chondroitin; D002809:Chondroitin Sulfates