Effect of Urtica dioica extract intake upon blood lipid profile in the rats.
Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile. Significant decreases in total cholesterol, LDL cholesterol, LDL/HDL cholesterol ratio and plasma total apo B were observed. Assessment of GOT, GPT and LDH activities showed that no liver damage has occurred during the study period.
Daher
Costantine F
CF
School of Arts and Sciences, Natural Science Division, Lebanese American University, P.O. Box 36, Byblos, Lebanon. cdaher@lau.edu.lb
Baroody
Karmen G
KG
Baroody
George M
GM
D000473:Alkanes / Q000737:chemistry; D000818:Animals; D004036:Diet, Atherogenic; D005243:Feces / Q000737:chemistry; D050356:Lipid Metabolism / Q000187:drug effects*; D008055:Lipids / Q000097:blood*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D026982:Urtica dioica / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D000473:Alkanes; D008055:Lipids; D010936:Plant Extracts; D014867:Water; C004544:naphtha