A case with sinonasal teratocarcinosarcoma in the nasal cavity and ethmoid sinus.
Sinonasal teratocarcinosarcoma (SNTCS) is a rare and aggressive malignant neoplasm histologically characterized by the combination of one or more epithelial elements and mesenchymal components. We report a 61-year-old man with SNTCS involving left nasal cavity and ethmoid sinus. He complained of left epistaxis for 1 week. Computed tomography and magnetic resonance imaging revealed a soft tissue filling the left middle meatus and ethmoid sinus, and effusion in the left sphenoid sinus but no invasion to the orbit or skull base. Tumor was completely removed with lateral rhinotomy, and post-operative radiation therapy (Liniac 60 Gy) was performed. Follow-up examination for 3 years and 5 months after the radiation therapy has shown no evidence of recurrence or metastasis. This report describes his clinical course, etiology, diagnosis and management of SNTCS with a review of literature.
Division of Otorhinolaryngology, Department of Translational Medical Science, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, 852-8501, Nagasaki, Japan. ktakasa@net.nagasaki-u.ac.jp
Kenji
K
Takasaki
Noriyuki
N
Sakihama
Haruo
H
Takahashi
D002296:Carcinosarcoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005005:Ethmoid Sinus / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000601:surgery; D009669:Nose Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013724:Teratoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D014057:Tomography, X-Ray Computed