Crossed cerebellar atrophy of prenatal onset.
BACKGROUND
Crossed cerebellar atrophy after hemorrhagic-ischemic injury in the contralateral cerebral hemisphere was reported in adults with stroke and in children with acquired lesions. It was also reported in preterm infants after perinatal or postnatal contralateral supratentorial lesions.


METHODS
We report crossed-cerebellar atrophy in a preterm neonate with prenatal posthemorrhagic ventriculomegaly and periventricular ischemic lesion in whom contralateral cerebellar involvement was detected on antenatal scans.


CONCLUSIONS
The result of our study suggests that in the developing brain, cross cerebellar atrophy may occur antenatally and that fetal MRI may help to identify such cases.
Department of Pediatrics, Neonatal Unit, Catholic University, Largo F. Vito 1, Rome 00136, Italy. francesca.gallini@fastwebnet.it
F
F
Gallini
R
R
Luciano
M
M
Pane
M P
MP
De Carolis
C
C
Romagnoli
E
E
Mercuri
D017668:Age of Onset; D001284:Atrophy / Q000473:pathology*; D002526:Cerebellar Diseases / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D007839:Functional Laterality; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D011296:Prenatal Diagnosis / Q000379:methods