A novel sequence variant in exon 7 of CYP2C9 gene (CYP2C9*24) in a patient on warfarin therapy.
Institute of Biochemistry, Faculty of Medicine, Vrazov trg 2, St-1000 Ljubljana, Slovenia.
Darja
D
Herman
Polona
P
Peternel
Mojca
M
Stegnar
Katja
K
Breskvar
Vita
V
Dolzan
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics* / Q000378:metabolism; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000378:metabolism; D065729:Cytochrome P-450 CYP2C9; D016903:Drug Monitoring; D005091:Exons / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D014859:Warfarin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases