Effect of formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens.
1. The effect of dietary formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens was studied. 2. An experiment with 120 Ross male broiler chickens was conducted from 1 to 42 d of age at the laboratory. There were 4 treatment groups: control (C), 10 mg/kg feed avilamycin (AV) and formic acid at two concentrations, 5 and 10 g/kg feed (FA5 and FA10, respectively). 3. No differences in weight gain, feed intake or feed conversion ratio were observed in male broiler chickens fed on the different diets. 4. An effect of the additives on ileal dry matter (DM) digestibility at 42 d of age was detected with the finisher diets; AV and 10 g/kg of feed formic acid slightly improved ileal DM digestibility compared to the other treatment groups. 5. Jejunum pH was not affected when 5 or 10 g/kg formic acid was added, and the results do not clearly show a positive effect of formic acid on the intestinal histomorphology. 6. No differences were noticed for blood metabolites in the different diets, and the levels of calcium and phosphorus in the plasma were not altered by formic acid addition. 7. In conclusion, when using broiler chickens under conditions of good hygiene, dietary formic acid did not have a clear positive effect on performance, intestinal histomorphology or plasma metabolite levels; however, there was a slight positive effect on the ileal digestibility of nutrients.
Department of Animal Production, University of Murcia, Murcia, Spain.
F
F
Hernández
V
V
García
J
J
Madrid
J
J
Orengo
P
P
Catalá
M D
MD
Megías
D000821:Animal Feed; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001769:Blood / Q000187:drug effects* / Q000378:metabolism; D002645:Chickens / Q000033:anatomy & histology / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D004032:Diet; D019587:Dietary Supplements; D004063:Digestion / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior; D005561:Formates / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000033:anatomy & histology* / Q000187:drug effects*; D008297:Male; D009844:Oligosaccharides / Q000494:pharmacology; D015430:Weight Gain / Q000187:drug effects
D000900:Anti-Bacterial Agents; D005561:Formates; D009844:Oligosaccharides; C030544:formic acid; C006653:avilamycin