Distinctive collection of fetal anomalies: cleft lip and palate, multicystic dysplastic kidneys, 1-2 syndactyly, heterotopic olivary tissue and thymic hypoplasia.
A female fetus with an unusual collection of congenital anomalies was detected prenatally. The pregnancy was terminated at 21 weeks of gestation. Clinical and pathological findings of bilateral cleft lip and palate, micrognathia, thymic hypoplasia, unilateral 1-2 finger syndactyly, bilateral multicystic dysplastic kidneys and heterotopic olivary tissue are presented. Differential diagnoses are discussed.
Tan
Tiong Yang
TY
Genetic Health Services Victoria, Royal Children's Hospital, Parkville, Victoria 3052, Australia. tiong.tan@ghsv.org.au
Nazaretian
Simon
S
McGillivray
George
G
Simpson
Ian
I
Bankier
Agnes
A
D000328:Adult; D002828:Choristoma / Q000151:congenital*; D002971:Cleft Lip / Q000150:complications*; D002972:Cleft Palate / Q000150:complications*; D005260:Female; D005333:Fetus / Q000002:abnormalities*; D005865:Gestational Age; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D021782:Multicystic Dysplastic Kidney / Q000150:complications*; D009847:Olivary Nucleus / Q000473:pathology; D013576:Syndactyly / Q000150:complications*; D013950:Thymus Gland / Q000002:abnormalities*