[Cholesterol crystal embolisation in the course of treatment with low-molecular-weight heparins].
Cholesterol crystal embolisation is a rare complication of anticoagulant treatment of ulcerative atheromatosis to the great arteries. The embolisation is susceptible to affect both, the somatic and the visceral territory; clinical diagnosis is difficult, mainly because of the similarity between the embolisation symptoms and those produced by a complication of primary disease. The diagnosis is certain when the pathological examination reveal the presence of cholesterol crystal in arteriolar lumen, surrounded by inflammatory- cellular reaction (foreign-body reaction). This paper presents three cases in which we noticed clinical manifestation suggestive for cholesterol crystal embolisation, at patients in treatment with low-molecular weight heparins. The complications which were reported in case of cholesterol crystal embolisation could be extremely severe, specially visceral embolisation, they may lead to patient's death.
Calotă
F
F
Clinica II Chirurgie, Spitalul Clinic Universitar de Urgenţă Craiova f.calota@dr.com
Vîlcea
D
D
Intorcaciu
M
M
Pâirvănescu
H
H
Enache
Doina
D
Comănescu
Violeta
V
Vasile
I
I
Scurtu
S
S
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D003460:Crystallization; D017700:Embolism, Cholesterol / Q000139:chemically induced*; D017809:Fatal Outcome; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight