[Ultrastructure of poly-DL-lactic acid as GTR membrane of soft tissue defects in goats palates].
OBJECTIVE
To study the ultrastructure changes of PDLLA as GTR membrane of soft tissue defects in the palates of goats.


METHODS
To establish penetrating rectangle palate defects in 8 goats. PDLLA membranes were implanted into the defect areas to guide the regeneration of the soft tissue defects. In 1, 2, 4, 6 months after the operation, the membranes were observed with scanning electron microscope.


RESULTS
The surface of PDLLA membrane was regular network before implantation. 1 month after the implantation, the edge of network became blunt. 2 months after the implantation, the surface of PDLLA membrane became coarse and irregular. 4 months after the implantation, PDLLA membrane network collapsed. 6 months after the implantation, PDLLA degraded into scraggly accumulation.


CONCLUSIONS
PDLLA membrane supplies good supporting function during concrescence of the soft tissue defects. PDLLA gradually loses mechanic intensity and is absorbed.
Luo
En
E
Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Hu
Jing
J
Ning
Qiu
Q
Yu
Lan
L
Zhou
Yong
Y
Wei
Shi-Cheng
SC
D000818:Animals; D006041:Goats; D019344:Lactic Acid; D010159:Palate; D011091:Polyesters; D011108:Polymers
D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)