[Mycosis fungoides-type eruptions induced by carbamazepine].
Cutaneous pseudolymphomas are inflammatory diseases of the skin that simulate malignant lymphomas in their clinical and/or histological form. Those induced by drugs are infrequent and are characterized by their clinical and histological polymorphism. There is no consensus regarding the definition of these dermatoses, and they can be seen in different forms of presentation. There are two main groups of drug-induced pseudolymphomas: those that clinically and histologically simulate cutaneous lymphomas, and those known as hypersensitivity syndromes. Pseudolymphomas cannot be differentiated from true lymphomas through clinical, pathological or molecular findings. The definitive test for diagnosis is the resolution of the lesions after the medication involved is suspended. We present three cases of carbamazepine-induced cases of pseudolymphomas that histologically simulate mycosis fungoides, with different clinical presentations.
Servicio de Dermatología, Hospital Universitario La Princesa, Madrid, Spain.
Sara
S
Alvarez-Ruiz
Yolanda
Y
Delgado
Maximiliano
M
Aragües
Javier
J
Fraga
Javier
J
Sánchez-Pérez
Jesús
J
Fernández-Herrera
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D002220:Carbamazepine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000473:pathology; D019310:Pseudolymphoma / Q000139:chemically induced* / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology
D000927:Anticonvulsants; D002220:Carbamazepine