Different degrees of right-to-left shunting predict migraine and stroke: data from 420 patients.
The authors analyzed the extent of right-to-left shunting in patients with migraine, patients with cryptogenic stroke, and controls. Patients with both migraine and stroke had larger shunts than did patients with migraine without stroke (p = 0.038), patients with no migraine with stroke (p = 0.007), and control patients (p < 0.0001). Patients with migraine have overall larger shunts than nonmigraineurs, particularly if they have had a stroke. Right-to-left shunting may be causally related to migraine and to the increased stroke risk of migraine.
Anzola
Gian Paolo
GP
ervizio di Neurologia, Ospedale S. Orsola FBF, Associazione Fatebenefratelli per la Ricerca (AFaR), Brescia, Italy. gpanzola@numerica.it
Morandi
Eva
E
Casilli
Francesco
F
Onorato
Eustaquio
E
D000328:Adult; D000368:Aged; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012189:Retrospective Studies; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016896:Treatment Outcome; D017585:Ultrasonography, Doppler, Transcranial