Sonographic signs of neutropenic enterocolitis.
OBJECTIVE
To investigate the sonographic features at time of diagnosis and follow-up in patients with neutropenic enterocolitis.


METHODS
The sonographic findings in 14 patients with neutropenic enterocolitis were described and evaluated regarding symptoms and clinical outcome.


RESULTS
In all patients with neutropenic enterocolitis, the ileocoecal region was involved with wall thickening >10 mm. A transmural inflammatory pattern, hypervascularity of the thickened bowel wall and free abdominal fluid were the common findings. The sonographically revealed thickness of the bowel wall was associated with lethal outcome (P<0.03). In the 11 surviving patients,the improvement of clinical symptoms was accompanied by progressive reduction of intestinal wall thickness.


CONCLUSIONS
High-end sonography of the bowel is a helpful tool for diagnosis,assessment of prognosis and follow-up of patients with neutropenic enterocolitis.The ultrasonographically revealed bowel thickness reflects the severity and the course of the disease, and seems to be predictive for the clinical outcome.
Dietrich
Christoph-F
CF
2nd Department of Internal Medicine, Caritas Hospital Bad Mergentheim, Bad Mergentheim, Germany. christoph.dietrich@ckbm.de
Hermann
Stella
S
Klein
Stefan
S
Braden
Barbara
B
D000328:Adult; D000368:Aged; D002432:Cecum / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D044504:Enterocolitis, Neutropenic / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007082:Ileum / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D011859:Radiography; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014463:Ultrasonography
D016179:Granulocyte Colony-Stimulating Factor