Mitochondrial protein import: convergent solutions for receptor structure.
Complex machinery has evolved to recognise and import nuclear-encoded proteins into mitochondria. Recent work now shows that the plant Tom20 mitochondrial protein import receptor has a similar tertiary structure to animal Tom20, although the proteins are evolutionarily distinct, representing an elegant example of convergent evolution.
Lister
Ryan
R
ARC Centre of Excellence in Plant Energy Biology, MCS Building M310, University of Western Australia, 35 Stirling Highway, Crawley 6009, Western Australia, Australia. seamus@cyllene.uwa.edu.au
Whelan
James
J
D000818:Animals; D019143:Evolution, Molecular; D005656:Fungal Proteins / Q000737:chemistry / Q000502:physiology; D005658:Fungi / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry* / Q000502:physiology; D008928:Mitochondria / Q000378:metabolism; D051336:Mitochondrial Membranes / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000737:chemistry* / Q000378:metabolism*; D010940:Plant Proteins / Q000737:chemistry / Q000502:physiology; D010944:Plants / Q000378:metabolism; D017434:Protein Structure, Tertiary; D021381:Protein Transport
D005656:Fungal Proteins; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D010940:Plant Proteins