[Functional state of calcitonin-producing cells of the female rats' thyroid as a result of experimental osteopenia therapy by graduated support loading combined with oestrogens and calcitonin injection].
Effects of graduated (2-hr.) support loading, synestrol and myocalcic on the thyroid C-cells was evaluated with the immunocytochemistry and cytomorphometry techniques. Graduated support loading was shown to partially recondition degraded functioning of C-cells. Synestrol injection suppressed the stimulating effect of support loading; myocalcic had a little effect on the C-cell activity. Simultaneous injection of two substances cancelled out the stimulating effect of support loading.
Loginov
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D000818:Animals; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001851:Bone Diseases, Metabolic / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D002116:Calcitonin / Q000008:administration & dosage / Q000096:biosynthesis / Q000627:therapeutic use*; D004028:Dienestrol / Q000008:administration & dosage / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004968:Estrogens, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D007273:Injections, Intramuscular; D051381:Rats; D013961:Thyroid Gland / Q000378:metabolism / Q000473:pathology*; D016896:Treatment Outcome; D016474:Weight-Bearing / Q000502:physiology*
D050071:Bone Density Conservation Agents; D004968:Estrogens, Non-Steroidal; D002116:Calcitonin; D004028:Dienestrol