Mobilization of hematopoietic progenitors in low-grade myelodysplastic syndromes.
Mobilization of hematopoietic progenitors in 15 untreated patients with low-grade myelodysplastic syndrome (IPSS score < or =1) resulted in poor yields in seven patients; moreover, mobilized cells had abnormal cytogenetics and defective in vitro growth. Only three out of 15 patients had adequate progenitor cell collections for potential use in autologous transplantation.
Mijovic
Aleksandar
A
Delforge
Michel
M
Sekhavat
Maryam
M
Czepulkowski
Barbara
B
Mufti
Ghulam J
GJ
D000328:Adult; D005240:Feasibility Studies; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D006412:Hematopoietic Stem Cells; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000628:therapy*; D016896:Treatment Outcome