Dietary lignan intakes and risk of breast cancer by tumor estrogen receptor status.
We examined the association of dietary lignan intake with estrogen receptor negative (ER-) and ER positive (ER+) breast cancer risk in a breast cancer case-control study. Among premenopausal women only, there was a reduced risk of ER- breast cancer for those in the highest compared to the lowest quartile of lignan intake suggesting that the observed negative association of lignans with breast cancer may be limited to ER- tumors.
Department of Epidemiology, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY, USA.
Susan E
SE
McCann
Swati
S
Kulkarni
Maurizio
M
Trevisan
Dominica
D
Vito
Jing
J
Nie
Stephen B
SB
Edge
Paola
P
Muti
Jo L
JL
Freudenheim
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000737:chemistry / Q000453:epidemiology* / Q000517:prevention & control; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D006801:Humans; D017705:Lignans / Q000008:administration & dosage*; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D016017:Odds Ratio; D048789:Phytoestrogens / Q000008:administration & dosage*; D017698:Postmenopause; D017697:Premenopause; D011960:Receptors, Estrogen / Q000032:analysis*; D018570:Risk Assessment; D012307:Risk Factors
D017705:Lignans; D048789:Phytoestrogens; D011960:Receptors, Estrogen