Optimal size and location for corneal rotational autografts: a simplified mathematical model.
OBJECTIVE
To calculate clinical guidelines for the optimal location and size of a rotational autokeratoplasty.


METHODS
The ideal graft size and trephine decentration for a rotational autograft were calculated based on scar location using geometric models. Mathematical variables were set to maximize postoperative visual acuity and for generalization of the geometric model. This model was used in a rotational autokeratoplasty of a patient with a history of a corneal scar and diplopia. An 8-mm autograft was decentered 0.5 mm superiorly and rotated 180 degrees to relocate the scar to the superior aspect of the cornea, out of the patient's vision.


RESULTS
For cases that satisfy the given variables, a graft diameter of 8 mm with a decentration of 0.5 mm balances maximization of scar removal and scar movement superiorly, with minimization of discrepancy in corneal thickness after rotation. For scars that are alpha degrees from horizontal, the graft should be rotated 180 - alpha degrees . By using these calculations, the autograft in this case successfully resolved the diplopia and improved visual acuity.


CONCLUSIONS
A rotational autograft can be an effective alternative to standard penetrating keratoplasty for some patients with corneal scars. We establish a mathematical model for most clinical instances of a rotational autograft, in which an 8-mm graft with a decentration of 0.5 mm best satisfies the goals of surgery.
Duke University Eye Center, Duke University Medical Center, Durham, NC 27710, USA. afsha003@mc.duke.edu
Natalie A
NA
Afshari
Scott M
SM
Duncan
Tasha Y
TY
Tanhehco
Dimitri T
DT
Azar
D000328:Adult; D003316:Corneal Diseases / Q000601:surgery; D016039:Corneal Transplantation / Q000379:methods*; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D014182:Transplantation, Autologous; D014792:Visual Acuity / Q000502:physiology