Three-dimensional sonographic evaluation of gallbladder contractility: comparison with cholescintigraphy.
OBJECTIVE
To compare three-dimensional sonography (3D US) with quantitative cholescintigraphy for assessing gallbladder contractility.


METHODS
Gallbladder radioactivity was assessed in 35 patients with suspected gallbladder disease using a gamma camera 5, 30, 60, and 90 minutes after technetium 99m (Tc-99m) DISIDA injection and 30 and 60 minutes after ingestion of a high-fat meal. Immediate gallbladder images were obtained via 3D US. Gallbladder radioactivity at 120 minutes after injection of Tc-99m DISIDA was defined as 100%, and gallbladder contractility was calculated. Gallbladder volume on 3D US was calculated using a dedicated software. Pearson correlation analysis and simple linear regression analysis were used.


RESULTS
The mean gallbladder volume on 3D US was 25.3 ml after fasting and 6.6 ml after a high-fat meal. The mean gallbladder contractility index was 77.7% on cholescintigraphy (range, 18-99) and 73.4 on 3D US (range, 16.7-97.3). A linear correlation between cholescintigraphy and 3D US contractility indices was observed. The r value on Pearson analysis was 0.92 and R(2) of the coefficient of determination was 0.85. The difference in measured contractility between the 2 methods ranged from +21.5% to -15.0% (mean +/- SD, 4.4 +/- 8.7%).


CONCLUSIONS
3D US is a reliable and easy method for clinical measurement of the volume of the gallbladder and its contractility.
Department of Radiology, Changwon Poutima Hospital, Changwon Kyungnam, Korea.
Hei Ja
HJ
Yoon
Pyo Nyun
PN
Kim
Ah Young
AY
Kim
Moon-Gyu
MG
Lee
D005704:Gallbladder / Q000000981:diagnostic imaging*; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging*; D016473:Gallbladder Emptying; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019785:Technetium Tc 99m Disofenin; D014463:Ultrasonography / Q000379:methods*
D019275:Radiopharmaceuticals; D019785:Technetium Tc 99m Disofenin