[Pulsed Doppler measurements of flow velocities in the intracranial and abdominal arteries of newborns of diabetic mothers].
OBJECTIVE
To define the character of haemodynamic changes and brain-sparing phenomena in newborns of diabetic mothers.


METHODS
On the basis of blood indices flow in the middle cerebral artery (MCA), anterior cerebral artery (ACA), right renal artery (RRA) and the superior mesenteric artery (SMA) the character of haemodynamic change and the brain-sparing phenomena in 53 newborns of diabetic mothers was analyzed. As a control group we chose 29 healthy newborns delivered at term. Doppler examinations were performed with ATL 3500 machine (Philips) using 7.5 MHz transducer and pulsed and colour Doppler. Pulsatility (PI) and resistance (RI) indices were calculated and analyzed.


RESULTS
In the MCA and ACA both indices (PI and RI) were lower than in abdominal arteries. We have found higher values of PI and RI in MCA than in ACA in both studied groups. In comparison to full-term newborns born from normal pregnancies, values of PI and RI in ACA were higher in IDM (infants of diabetic mothers) group (p<0.01).


CONCLUSIONS
In IDM similarly to neonates from physiological pregnancies we can observe physiological phenomenon of brain-sparing effect. In the IDM group postnatal haemodynamic disturbances are limited to the brain circulation only. In IDM in spite of absence of signs of hypoxia, some brain-sacrifice effect was observed. Haemodynamic disturbances were not observed in renal and mesenteric circulation.
Bokiniec
Renata
R
Klinika Neonatologii II Katedry Połoznictwa i Ginekologii, Akademia Medyczna, ul. Karowa 2, 00-315 Warszawa, Poland.
Kornacka
Maria Katarzyna
MK
Czajkowski
Krzysztof
K
D001783:Blood Flow Velocity; D002536:Cerebral Arteries / Q000000981:diagnostic imaging; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D008297:Male; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging*; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging*; D011044:Poland; D011247:Pregnancy; D011254:Pregnancy in Diabetics; D011297:Prenatal Exposure Delayed Effects / Q000000981:diagnostic imaging*; D012077:Renal Artery / Q000000981:diagnostic imaging*; D018617:Ultrasonography, Doppler, Pulsed; D014652:Vascular Diseases / Q000000981:diagnostic imaging*