Imaging gene expression.
Genome-wide sequencing and increasing use of microarrays has resulted in the identification of a large number of new genes which may have important functional roles in development and onset of disease. Classical approaches in gene expression studies fall short in providing information about cellular localization of these genes and their relative levels of expression in tissues. Rapid determination of gene expression can be achieved with in situ methods of localization of gene expression in combination with recent developments in imaging technology.
Division of Nephrology, Indiana University School of Medicine, Indianapolis, Ind 46236, USA. rbacalla@iupui.edu
Rajesh
R
Kher
Robert L
RL
Bacallao
D000818:Animals; D003952:Diagnostic Imaging; D015870:Gene Expression; D006801:Humans; D017403:In Situ Hybridization; D012313:RNA / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction
D012313:RNA