Positron emission tomography in well differentiated fetal adenocarcinoma of the lung.
A 47-year-old woman with a 20 pack-year history of cigarette smoking presented with a chest x-ray demonstrating a left upper lobe lung density. Computed tomography of the chest showed a 3-cm lobulated mass in the apical left upper lobe. The lesion demonstrated intense focal uptake on FDG-PET scanning. The patient underwent left upper lobectomy. Pathology demonstrated the histologic and immunohistochemical findings of a well differentiated fetal adenocarcinoma (WDFA). The intense FDG-PET uptake and abundant glycogen stores associated with WDFA may be the result of its embryonic derivation and differential expression of glucose transporter proteins.
Paull
Douglas E
DE
Department of Surgery, Department of Veterans Affairs Medical Center, Dayton, OH 45428, USA. douglas.paull@wright.edu
Moezzi
Jazbieh
J
Katz
Neil
N
Little
Alex G
AG
Adebonojo
Samuel A
SA
D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18