Facile preparation of biodegradable chitosan derivative having poly(butylene glycol adipate) side chains.
Various modes are being explored for the construction of functional materials from nanoparticles. Despite these efforts, the assembly of nanoparticles remains challenging with respect to the requirement of multiple component organization on varying dimensions and length scales. The graft copolymers of chitosan with poly(butylene glycol adipate) (PBGA) were prepared due to the esterification reaction between PBGA and 6-O-succinate-N-phthaloyl-chitosan (PHCSSA) in the presence of toluene as a swelling agent. The graft copolymers are nanoparticles with the size of few hundred nanometers as observed from TEM. It is a potential method to combine chitosan with the hydrophobic synthetic polymers. The grafting reactions were conducted with various PBGA/PHCSSA feed ratios to obtain chitosan-g-PBGA copolymers with various PBGA contents. FT-IR, NMR, XRD, spectrofluorophotometer, and TEM were detected to characterize the copolymers.
Huang
Meifang
M
Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.
Fang
Yue'e
Y
D001673:Biodegradation, Environmental; D001704:Biopolymers / Q000737:chemistry / Q000302:isolation & purification; D002072:Butylene Glycols / Q000737:chemistry* / Q000302:isolation & purification; D048271:Chitosan / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008854:Microscopy, Electron; D015394:Molecular Structure; D049329:Nanostructures; D011108:Polymers / Q000737:chemistry* / Q000302:isolation & purification; D013050:Spectrometry, Fluorescence; D017550:Spectroscopy, Fourier Transform Infrared; D013816:Thermodynamics; D014961:X-Ray Diffraction
D001704:Biopolymers; D002072:Butylene Glycols; D011108:Polymers; C009204:butylene glycol adipic acid polyester; D048271:Chitosan