Coexistence of Crohn's disease and inflammatory fibroid polyp of the small bowel. Report of a case and review of the literature.
OBJECTIVE
The Authors report a case of a woman aged 35, with concurrent appearance of Crohns disease and Inflammatory Fibroid Polyp of the terminal ileum.


METHODS
The combination of the two disorders was clinically manifested as an obstructive ileus. On the operative table, a 4-cm polypoid mass causing intussusception of the bowel was obvious. The resected specimen of the ileum showed profound distention, several ulcerations and fissures. The histological examination confirmed the diagnosis of Crohn's disease coexisting with an Inflammatory Fibroid Polyp. Immunostaining of the lesion for actin showed focal positivity. However, staining for desmin, CD31, S100-protein, PGM-1 CD34, CD117, and bc1-2, was negative.


CONCLUSIONS
Coexistence of Inflammatory Fibroid Polyp with Crohn's disease causing obstructive ileus could be the first manifestation of the disease. The combination of the two disorders corroborates the reparative character of the lesion. Nevertheless, the exact etiopathogenetic relationship between the two entities remains obscure.
Department of Pathology, "Agios Panteleimon" General State Hospital, Nicea, Greece.
Aikaterini
A
Parasi
John K
JK
Triantafillidis
Charalambos
C
Barbatzas
Antigoni
A
Karakosta
Nicolas
N
Condilis
Helen
H
Sotiriou
D000006:Abdomen, Acute / Q000209:etiology; D000328:Adult; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D004630:Emergencies; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D007082:Ileum / Q000473:pathology; D007150:Immunohistochemistry; D007417:Intestinal Polyps / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D007443:Intussusception / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000601:surgery; D007813:Laparotomy