Iron nanoparticles in the coupling of alkyl halides with aryl Grignard reagents.
Iron nanoparticles, either formed in situ stabilized by 1,6-bis(diphenylphosphino)hexane or polyethylene glycol (PEG), or preformed stabilized by PEG, are excellent catalysts for the cross-coupling of aryl Grignard reagents with primary and secondary alkyl halides bearing beta-hydrogens and they also prove effective in a tandem cyclization/cross-coupling reaction.
Bedford
Robin B
RB
School of Chemistry, University of Bristol, Cantock's Close, Bristol, UKBS8 1TS. r.bedford@bristol.ac.uk
Betham
Michael
M
Bruce
Duncan W
DW
Davis
Sean A
SA
Frost
Robert M
RM
Hird
Michael
M