The structure of the lipid anchor of Campylobacter jejuni polysaccharide.
Campylobacter jejuni is a leading cause of gastroenteritis in humans. Campylobacter jejuni produces extracellular polysaccharides that have been characterized structurally and shown to be independent of lipopolysaccharides. Furthermore, it has been suggested that these C. jejuni polysaccharides are capsular in nature, although their lipid anchor has not been identified. In this report, the occurrence of a lipid-linked capsular-like polysaccharide in C. jejuni is conclusively shown, and the lipid anchor identified as dipalmitoyl-glycerophosphate.
Department of Microbiology, National University of Ireland, Galway, Ireland.
Adrian T
AT
Corcoran
Heidi
H
Annuk
Anthony P
AP
Moran
D016667:Bacterial Capsules / Q000737:chemistry; D016123:Campylobacter jejuni / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D004586:Electrophoresis; D008055:Lipids / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis / Q000737:chemistry; D011135:Polysaccharides, Bacterial / Q000032:analysis*
D008055:Lipids; D010743:Phospholipids; D011135:Polysaccharides, Bacterial