[Macro-aspartate aminotransferase in a patient with chronic hepatitis C].
Macroenzymes are normal enzymes complexed with an immunoglobulin (usually IgG, rarely IgA or IgM). A number of macroenzymes have been reported in the literature. Among them, macro-AST has been detected in diseases such as acute and chronic hepatitis, various malignancies and autoimmune diseases, but usually not associated with any specific disease. We report a case of elevated AST activity in serum due to marco-AST formation in a female with chronic hepatitis C which was confirmed by AST isoenzyme electrophoresis. To our knowledge, this is the first report of macro-AST occurred in chronic hepatitis patient in Korea.
Chung
Yong Woo
YW
Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.
Sohn
Joo Hyun
JH
Baek
Chang Hee
CH
Kim
Jong Pyo
JP
Jeon
Yong Cheol
YC
Han
Dong Soo
DS
Lee
Dong Hoo
DH
Kee
Choon Suhk
CS
Park
Il Kyu
IK
D001219:Aspartate Aminotransferases / Q000097:blood*; D005260:Female; D019698:Hepatitis C, Chronic / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008875:Middle Aged
D007527:Isoenzymes; D001219:Aspartate Aminotransferases