[Macro-aspartate aminotransferase in a patient with chronic hepatitis C].
Macroenzymes are normal enzymes complexed with an immunoglobulin (usually IgG, rarely IgA or IgM). A number of macroenzymes have been reported in the literature. Among them, macro-AST has been detected in diseases such as acute and chronic hepatitis, various malignancies and autoimmune diseases, but usually not associated with any specific disease. We report a case of elevated AST activity in serum due to marco-AST formation in a female with chronic hepatitis C which was confirmed by AST isoenzyme electrophoresis. To our knowledge, this is the first report of macro-AST occurred in chronic hepatitis patient in Korea.
Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.
Yong Woo
YW
Chung
Joo Hyun
JH
Sohn
Chang Hee
CH
Baek
Jong Pyo
JP
Kim
Yong Cheol
YC
Jeon
Dong Soo
DS
Han
Dong Hoo
DH
Lee
Choon Suhk
CS
Kee
Il Kyu
IK
Park
D001219:Aspartate Aminotransferases / Q000097:blood*; D005260:Female; D019698:Hepatitis C, Chronic / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008875:Middle Aged
D007527:Isoenzymes; D001219:Aspartate Aminotransferases