Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection.
Reported here are two cases of hantavirus pulmonary syndrome caused by Puumala virus infection, which rapidly resolved after initiation of corticosteroid treatment combined with continuous veno-venous hemodiafiltration. These cases emphasize the role of the inflammatory response in the pathogenesis of hantavirus pulmonary syndrome.
Seitsonen
E
E
Department of Anesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Stenbäckinkatu 11, P.O. B 281, 00029 HUS, Helsinki, Finland. elina.seitsonen@hus.fi
Hynninen
M
M
Kolho
E
E
Kallio-Kokko
H
H
Pettilä
V
V
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D018804:Hantavirus Pulmonary Syndrome / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006440:Hemofiltration; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D029262:Puumala virus / Q000302:isolation & purification; D011859:Radiography
D000305:Adrenal Cortex Hormones