Creutzfeldt-Jakob disease presenting with alien limb sign.
Creutzfeldt-Jakob disease is a fatal spongiform encephalopathy, which typically presents with a rapidly progressing dementia and additional neurological findings that can be quite variable and diverse. Here we report the unusual case of a patient who presented with left alien limb sign without overt cognitive impairment and was ultimately diagnosed with pathologically confirmed Creutzfeldt-Jakob disease.
Department of Neurology, UCLA Medical Center, Los Angeles, California 90095, USA. bfogel@ucla.edu
Brent
B
Fogel
Mark
M
Wu
Sarah
S
Kremen
Kolar
K
Murthy
George
G
Jackson
Zeba
Z
Vanek
D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D018450:Disease Progression; D004292:Dominance, Cerebral / Q000502:physiology; D004421:Dystonia / Q000175:diagnosis / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008875:Middle Aged; D009460:Neurologic Examination; D010468:Perceptual Disorders / Q000175:diagnosis* / Q000209:etiology; D011328:Prions / Q000032:analysis
D011328:Prions