Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine.
The anti-hepatitis B virus activity and hepatoprotective activity of a liquid fermentation broth of Ganoderma lucidum were investigated. The cultured broth was supplemented with aqueous extract of Radix Sophorae flavescentis, a kind of Chinese herbal medicine. Our results indicated that the cultured broth had effects of anti-hepatitis B virus activity in vitro and protected mice from liver damage in vivo. Our results also indicated that the co-fermentation broth of Ganoderma lucidum in the presence of aqueous extract of Radix Sophorae flavescentis has better medicinal effects than simply mixing these two ingredients together, suggesting a potential novel way to prepare Chinese herbal mixtures.
Li
Yanqun
Y
College of Life Science, South China Normal University, Guangzhou 510631, China. liyq9168@hotmail.com
Yang
Yailong
Y
Fang
Lu
L
Zhang
Zhibin
Z
Jin
Jian
J
Zhang
Kechang
K
D000818:Animals; D045744:Cell Line, Tumor; D004365:Drugs, Chinese Herbal; D006515:Hepatitis B virus / Q000187:drug effects*; D006524:Hepatitis, Viral, Animal / Q000188:drug therapy*; D006801:Humans; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D020940:Reishi / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts