[Effect of early enteral nutrition on immune function of the patients after operation for severe abdominal trauma].
OBJECTIVE
To determine the effect of early enteral nutrition (EN) on immune function of the patients after operation for severe abdominal trauma.


METHODS
Fourty patients who underwent operation for severe abdominal trauma were randomly divided into two groups, and received an early enteral nutrition (EN group, n=20) through jejunal nutritional tube from postoperative day 1, or parental nutrition (PN group, n=20) for 7 days. C3, IgA, IgM, IgG and CD3+, CD4+, CD8+, CD4+/CD8+ of the two groups patients were detected on the day before operation and the postoperative day 1 and 8. The infection complications were compared.


RESULTS
After 7 days, the levels of C3+, IgA, IgG, CD3+, CD4+, CD8+, and CD4+/CD8+ in EN group increased significantly compared with those in PN group (P< 0.05). The incidence of infection was 10% in EN group, while 30% in PN group (P< 0.05).


CONCLUSIONS
Early enteral nutrition can improve immune function and decrease postoperative infection after operation for severe abdominal trauma.
Department of Surgery, Shajing Peoples Hospital, Shenzhen 518104, China. dgh_cjf@163.com
Gong-hang
GH
Dong
Ju-fang
JF
Cai
Jun
J
Hao
Qi-Guang
QG
Zhong
Ying-jun
YJ
Li
D000007:Abdominal Injuries / Q000276:immunology* / Q000601:surgery; D000293:Adolescent; D000328:Adult; D017252:CD3 Complex / Q000032:analysis; D015704:CD4 Antigens / Q000032:analysis; D016516:CD4-CD8 Ratio; D016827:CD8 Antigens / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D011184:Postoperative Period; D055815:Young Adult
D017252:CD3 Complex; D015704:CD4 Antigens; D016827:CD8 Antigens; D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G