Striae and pelvic relaxation: two disorders of connective tissue with a strong association.
Pelvic relaxation, a weakening of pelvic support structures, is an under-reported condition that affects a multitude of women. In the United States alone, more than 338,000 procedures for prolapse are performed annually. Decreased collagen content has been noted in the tissues of women affected by this condition. Interestingly, biopsy specimens of women with striae also show a diminution of collagen. Using self-reported anonymous data, we compared the prevalence of striae in women with and without pelvic relaxation to see if an association between these two disorders of connective tissue existed. More than half the women with prolapse (54.7%) (n = 41) reported striae, whereas only 25.0% of women in the non-prolapse group (n = 8) reported striae (P < 0.01). Multivariate logistic regression analysis confirmed striae as a significant risk factor for the development of clinical prolapse (odds ratio 3.12, P < 0.05). There appears to be a strong association between the presence of striae and the development of pelvic relaxation, which is unrelated to conventionally cited risk factors, such as age, weight, number of pregnancies, or postmenopausal status.
Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Sharon A
SA
Salter
Ritu S
RS
Batra
Thomas E
TE
Rohrer
Neeraj
N
Kohli
Alexa B
AB
Kimball
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002921:Cicatrix / Q000453:epidemiology* / Q000473:pathology*; D003625:Data Collection; D005260:Female; D006801:Humans; D008875:Middle Aged; D017773:Pelvic Floor / Q000473:pathology*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000473:pathology*; D015995:Prevalence; D012307:Risk Factors; D001745:Urinary Bladder Diseases / Q000453:epidemiology / Q000473:pathology; D014596:Uterine Prolapse / Q000453:epidemiology / Q000473:pathology