Temporal distribution and parasite load kinetics in blood and tissues during Neospora caninum infection in mice.
The kinetics of Neospora caninum loads in mice inoculated with NC-Liv or NC-1 isolates were studied. The acute phase was characterized by parasitemia and the detection of parasite DNA in several organs, whereas during the chronic phase, the parasite was detected mainly in the brain. Mice infected with NC-Liv developed clinical signs, showing higher brain parasite burdens than NC-1-infected mice.
Collantes-Fernández
Esther
E
Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Ciudad Universitaria, E-28040 Madrid, Spain.
López-Pérez
Inmaculada
I
Alvarez-García
Gema
G
Ortega-Mora
Luis M
LM
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001921:Brain / Q000276:immunology / Q000469:parasitology; D002908:Chronic Disease; D003048:Coccidiosis / Q000097:blood* / Q000401:mortality / Q000469:parasitology* / Q000503:physiopathology; D005260:Female; D007700:Kinetics; D008099:Liver / Q000276:immunology / Q000469:parasitology; D008168:Lung / Q000276:immunology / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C; D018688:Neospora / Q000254:growth & development* / Q000276:immunology* / Q000302:isolation & purification; D009928:Organ Specificity / Q000276:immunology; D013154:Spleen / Q000276:immunology / Q000469:parasitology
D000913:Antibodies, Protozoan