[Cholesterol crystal embolisation in the course of treatment with low-molecular-weight heparins].
Cholesterol crystal embolisation is a rare complication of anticoagulant treatment of ulcerative atheromatosis to the great arteries. The embolisation is susceptible to affect both, the somatic and the visceral territory; clinical diagnosis is difficult, mainly because of the similarity between the embolisation symptoms and those produced by a complication of primary disease. The diagnosis is certain when the pathological examination reveal the presence of cholesterol crystal in arteriolar lumen, surrounded by inflammatory- cellular reaction (foreign-body reaction). This paper presents three cases in which we noticed clinical manifestation suggestive for cholesterol crystal embolisation, at patients in treatment with low-molecular weight heparins. The complications which were reported in case of cholesterol crystal embolisation could be extremely severe, specially visceral embolisation, they may lead to patient's death.
Clinica II Chirurgie, Spitalul Clinic Universitar de Urgenţă Craiova f.calota@dr.com
F
F
Calotă
D
D
Vîlcea
M
M
Intorcaciu
H
H
Pâirvănescu
Doina
D
Enache
Violeta
V
Comănescu
I
I
Vasile
S
S
Scurtu
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D003460:Crystallization; D017700:Embolism, Cholesterol / Q000139:chemically induced*; D017809:Fatal Outcome; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight