[Excitation and inhibition in monosynaptic reflex arcs of white rats in conditions of spinal hyperreflexia].
The mechanisms of excitation and inhibition in monosynaptic reflex arcs of white rats in conditions of spinal superreflexion (a state, in which the amplitude of reflex monosynaptic discharges of a ventral root (MD VR) is close to a threshold of excitation of motoneurons axon) were investigated. The character of MD VR during recording of their reflex discharges from cut and uncut VR was studied. Previously established pattern MR VR generation as extremely high voltage and presence of its second component are observed in these conditions. In a state of superreflexion intersegmental interactions getting weaker and are particularly characterized by inhibitive influences from segment L4 on motoneurons of segment L5. It is shown that in animals with spinal superreflexion expression of the antidromic inhibition is weaker compare to intact ones. It was defined that reciprocal interrelations of flexor and extensor motoneurons are maintained and even strengthen.
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Rodyns'kyĭ
D000818:Animals; D017763:Autonomic Denervation; D020211:Autonomic Dysreflexia / Q000503:physiopathology*; D004195:Disease Models, Animal; D004558:Electric Stimulation; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology*; D008161:Lumbosacral Region; D009046:Motor Neurons / Q000502:physiology*; D018482:Muscle, Skeletal / Q000294:innervation / Q000502:physiology*; D051381:Rats; D012023:Reflex, Monosynaptic / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*