Effect of Urtica dioica extract intake upon blood lipid profile in the rats.
Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile. Significant decreases in total cholesterol, LDL cholesterol, LDL/HDL cholesterol ratio and plasma total apo B were observed. Assessment of GOT, GPT and LDH activities showed that no liver damage has occurred during the study period.
School of Arts and Sciences, Natural Science Division, Lebanese American University, P.O. Box 36, Byblos, Lebanon. cdaher@lau.edu.lb
Costantine F
CF
Daher
Karmen G
KG
Baroody
George M
GM
Baroody
D000473:Alkanes / Q000737:chemistry; D000818:Animals; D004036:Diet, Atherogenic; D005243:Feces / Q000737:chemistry; D050356:Lipid Metabolism / Q000187:drug effects*; D008055:Lipids / Q000097:blood*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D026982:Urtica dioica / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D000473:Alkanes; D008055:Lipids; D010936:Plant Extracts; D014867:Water; C004544:naphtha