[Stem cell therapy in ischemic heart disease].
Stem cell therapy is a treatment of great potential, including in cardiology. In the past few years, it has been shown that the heart has the potential for regeneration. Clinical studies have shown that intracoronary or intracardiac transplantation of bone marrow stem cells to patients with chronic or acute ischemic heart diseases improves the function and regional myocardial perfusion of the left ventricle. No significant complications have been described. However, since there is no evidence on morbidity or mortality, there is a great need for further research before the treatment can be implemented in the daily clinic.
Diederichsen
Axel Cosmus Pyndt
AC
Odense Universitetshospital, Center for Stamcellebehandling, Kardiologisk Afdeling B, Odense C. a.diederichsen@dadlnet.dk
Møller
Jacob Eifer
JE
Kristiansen
Malthe A M
MA
Saekmose
Susanne Gjørup
SG
Barington
Torben
T
Videbaek
Lars M
LM
Kassem
Moustapha S
MS
Thayssen
Per
P
D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000379:methods; D002986:Clinical Trials as Topic; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D017202:Myocardial Ischemia / Q000628:therapy*; D015425:Myocardial Reperfusion; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D033581:Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods