A synthetic receptor for phosphocholine esters.
A bifunctional Zn-salen modified cavitand, reminiscent of the enzyme phospholipase C, shows high efficiency and synergic effect in the binding of the phospholipid DOPC.
Skaggs Institute for Chemical Biology and Department of Chemistry, Scripps Research Institute, MB-26, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Felix H
FH
Zelder
Riccardo
R
Salvio
Julius
J
Rebek
D001665:Binding Sites; D004952:Esters; D005029:Ethylenediamines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010767:Phosphorylcholine / Q000737:chemistry*; D013816:Thermodynamics; D015032:Zinc / Q000737:chemistry*
D004952:Esters; D005029:Ethylenediamines; D009942:Organometallic Compounds; D010767:Phosphorylcholine; C011452:disalicylaldehyde ethylenediamine; D015032:Zinc