Biochemistry of prostaglandins A.
This review considers modern concepts on the structural-functional properties and antiproliferative, antitumor, and antiviral effects of cyclopentenone prostaglandins A and mechanisms underlying their actions. Possible directions of pharmacological application of these compounds and their analogs are discussed.
Hubich
A I
AI
Belarus State University, Minsk.
Sholukh
M V
MV
D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism; D000998:Antiviral Agents / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D015394:Molecular Structure; D011454:Prostaglandins A / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011982:Receptors, Prostaglandin / Q000378:metabolism
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D011454:Prostaglandins A; D011982:Receptors, Prostaglandin