Dietary lignan intakes and risk of breast cancer by tumor estrogen receptor status.
We examined the association of dietary lignan intake with estrogen receptor negative (ER-) and ER positive (ER+) breast cancer risk in a breast cancer case-control study. Among premenopausal women only, there was a reduced risk of ER- breast cancer for those in the highest compared to the lowest quartile of lignan intake suggesting that the observed negative association of lignans with breast cancer may be limited to ER- tumors.
McCann
Susan E
SE
Department of Epidemiology, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY, USA.
Kulkarni
Swati
S
Trevisan
Maurizio
M
Vito
Dominica
D
Nie
Jing
J
Edge
Stephen B
SB
Muti
Paola
P
Freudenheim
Jo L
JL
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000737:chemistry / Q000453:epidemiology* / Q000517:prevention & control; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D006801:Humans; D017705:Lignans / Q000008:administration & dosage*; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D016017:Odds Ratio; D048789:Phytoestrogens / Q000008:administration & dosage*; D017698:Postmenopause; D017697:Premenopause; D011960:Receptors, Estrogen / Q000032:analysis*; D018570:Risk Assessment; D012307:Risk Factors
D017705:Lignans; D048789:Phytoestrogens; D011960:Receptors, Estrogen