Three-dimensional chiral imaging by sum-frequency generation.
A sum-frequency generation (SFG) microscope that is sensitive toward molecular chirality was demonstrated for the first time. Optically active images of chiral 1,1'-bi-2-naphthol solutions were obtained with submicron spatial resolution. Three-dimensional sectioning capability of our microscope was also demonstrated. This optically active SFG microscopy can potentially become a powerful imaging technique for biological samples.
Ji
Na
N
Department of Physics, University of California at Berkeley, Berkeley, California 94720, USA.
Zhang
Kai
K
Yang
Haw
H
Shen
Yuen-Ron
YR
D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008856:Microscopy, Fluorescence / Q000379:methods; D009284:Naphthols / Q000737:chemistry*; D013237:Stereoisomerism
C406944:BINOL, naphthol; D009284:Naphthols