Allergic contact dermatitis from propolis.
Propolis is commonly used in cosmetic and medicinal preparations because of its antiseptic, antiinflammatory, and anesthetic properties. Its therapeutic qualities have been well documented. However, 1.2 to 6.6% of patients who are patch-tested for dermatitis are sensitive to propolis. The main allergens are 3-methyl-2-butenyl caffeate and phenylethyl caffeate. Benzyl salicylate and benzyl cinnamate are less frequent sensitizers. Propolis is found in a number of "natural" products, including lip balms, cosmetics, lotions and ointments, shampoos, conditioners, and toothpastes. Dermatologists should consider patch testing with propolis in users of such remedies.
Walgrave
Susan E
SE
University of Minnesota, School of Medicine, Minneapolis, MN, USA.
Warshaw
Erin M
EM
Glesne
Lynn A
LA
D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000737:chemistry / Q000276:immunology; D003358:Cosmetics / Q000009:adverse effects / Q000737:chemistry; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D006801:Humans; D011429:Propolis / Q000009:adverse effects* / Q000737:chemistry / Q000276:immunology
D000890:Anti-Infective Agents; D003358:Cosmetics; D011429:Propolis