[Methodological approaches to quantitative immunohistochemical evaluation of expression of breast apoptosis and proliferation markers].
Apoptosis and proliferative markers were studied in fibroadenoma and fibrocystic breast lesions. A quantitative immunohistochemical test for these factors using computer system of microscopic images is presented. It provides the advantages for interpretation of immunohistochemical reactions by design of expression standards for different pathologies in the breast.
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IN
Kostiuchek
I Iu
IIu
Kogan
I M
IM
Kvetnoĭ
D017209:Apoptosis; D014408:Biomarkers, Tumor / Q000378:metabolism; D001940:Breast / Q000378:metabolism* / Q000473:pathology; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D005348:Fibrocystic Breast Disease / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods
D014408:Biomarkers, Tumor