A synthetic receptor for phosphocholine esters.
A bifunctional Zn-salen modified cavitand, reminiscent of the enzyme phospholipase C, shows high efficiency and synergic effect in the binding of the phospholipid DOPC.
Zelder
Felix H
FH
Skaggs Institute for Chemical Biology and Department of Chemistry, Scripps Research Institute, MB-26, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Salvio
Riccardo
R
Rebek
Julius
J
D001665:Binding Sites; D004952:Esters; D005029:Ethylenediamines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010767:Phosphorylcholine / Q000737:chemistry*; D013816:Thermodynamics; D015032:Zinc / Q000737:chemistry*
D004952:Esters; D005029:Ethylenediamines; D009942:Organometallic Compounds; D010767:Phosphorylcholine; C011452:disalicylaldehyde ethylenediamine; D015032:Zinc