Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients.
We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients. Between 1985 and 2003, we treated 109 keloid scars in 94 patients by injecting 1 to 10?mg of triamcinolone acetonide depending on the size of the lesion at four week intervals. There was little morbidity. Thirty-one patients gave up treatment within 10 injections because of pain and lack of immediate improvement. Improvement in subjective symptoms was seen in 52 of the remaining 63 patients (82%). In objective symptoms, fair or better results were seen in 40 of 63 (63%), and good or better results in 25 of 63 (39%). The treatment method required 20-30 injections over three to five years. Although we did not achieve as good results as other authors, we think it was safer because we used a smaller dose of a steroid.
Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Kagawa University, Kita, Kagawa, Japan. muneuchi@med.kagawa-u.ac.jp
Gan
G
Muneuchi
Shigehiko
S
Suzuki
Masayuki
M
Onodera
Osamu
O
Ito
Yuiro
Y
Hata
Hiroharu H
HH
Igawa
D000293:Adolescent; D000328:Adult; D000368:Aged; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002921:Cicatrix / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015552:Injections, Intralesional / Q000706:statistics & numerical data; D007627:Keloid / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000627:therapeutic use*
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide