Production of Bacteriophage-Associated Materials by Vibrio cholerae: Possible Correlation with Pathogenicity.
Classical and El Tor strains of Vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin C-induced cultures. The strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. Of the 27 strains tested, 25 showed a correlation between the production of bacteriophage-related material and pathogenicity. Both P(+) and P(-) strains produced bacteriophage tails. The bacteriophage tails of strains 569B and ATCC 9168 and other strains were shown to occur in an extended form with tail appendages.
Department of Bacteriology, University of California, Los Angeles, California 90024.
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Parker
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Richardson
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Romig