[Angiogenesis--a novel therapeutic strategy for cardiovascular diseases].
Angiogenesis is a biological process of growing new vessels from the existed vascular structure. Many factors, such as vascular endothelia growth factor and fibroblast growth factor, can stimulate the formation of new vessels. Promoting revascularization in ischemic myocardium has been a novel therapeutic strategy for ischemic cardiovascular diseases. Recently, investigators have done a lot of work in experimental researches and clinical trials, and made some progress. Nevertheless, there are still some problems to be solved in therapeutic angiogenesis. Clinical validity of traditional Chinese medicinal treatment and its therapeutic principles including strengthening qi and activating blood, removing blood stasis to stimulate generation of blood, etc. are the theoretic and clinical basis for TCM study on angiogenesis.
Wang
Pei-li
PL
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091. wpl0721@sohu.com
Lei
Yan
Y
Chen
Ke-ji
KJ
D043925:Angiogenesis Inducing Agents / Q000627:therapeutic use*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D018919:Neovascularization, Physiologic; D008517:Phytotherapy
D043925:Angiogenesis Inducing Agents; D004365:Drugs, Chinese Herbal