[Effect of immunoglobulins on morphological structure of the brain occipital part in experimental allergic encephalomyelitis].
We studied the structure of the occipital part of brain in rats with experimental allergic encephalomyelitis (EAE), which were treated with intraperitoneal injections of intravenous immunoglobulin from 12th to 15th day after EAE induction. All rats were divided on tree groups: the first group and the second group received human intravenous immunoglobulin and rat immunoglobulin, respectively and the third group serves as a control group. We observed more expressed vascular edema and nervous cells alterations in control group in comparison to the treated groups. Therefore intravenous immunoglobulin improves the state of the occipital part of brain in rats with EAE.
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D000818:Animals; D004195:Disease Models, Animal; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D007274:Injections, Intraperitoneal; D009474:Neurons / Q000187:drug effects / Q000473:pathology*; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D009778:Occipital Lobe / Q000187:drug effects / Q000473:pathology*; D051381:Rats
D016756:Immunoglobulins, Intravenous; D018696:Neuroprotective Agents