Utilization of L-alpha-nucleobase amino acids (NBAs) as protein engineering tools: construction of NBA-modified HIV-1 protease analogues and enhancement of dimerization induced by nucleobase interaction.
Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta, Yokohama 226-8501, Japan. ttakahas@bio.titech.ac.jp
Tsuyoshi
T
Takahashi
Dewi
D
Yana
Hisakazu
H
Mihara
D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D020029:Base Pairing; D002087:Butyrates / Q000737:chemistry; D002384:Catalysis; D019281:Dimerization; D016333:HIV Protease / Q000737:chemistry*; D008958:Models, Molecular; D009711:Nucleotides / Q000737:chemistry*; D011487:Protein Conformation; D015202:Protein Engineering / Q000379:methods; D017510:Protein Folding; D017434:Protein Structure, Tertiary
D000596:Amino Acids; D002087:Butyrates; D009711:Nucleotides; D016333:HIV Protease