The role of inhaled long-acting beta-2 agonists in the management of asthma.
The role of inhaled beta-2 agonists in the management of asthma has changed significantly over the last several years. This review outlines the most recent understanding of the pathophysiology of asthma and the studies that define the roles that both short- and long-acting beta-2 agonists play in therapy for this disease. A concentration on the clinical pharmacology and genetic implications for clinical use of this class of drugs in accordance with the national and international guidelines are described.
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
H William
HW
Kelly
Michelle S
MS
Harkins
Homer
H
Boushey
D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000235:genetics / Q000503:physiopathology; D006801:Humans
D000318:Adrenergic beta-Agonists; D018927:Anti-Asthmatic Agents