[Preparation and properties of calcium silicate-phosphate composite bone cements].
In this paper, alpha-tricalcium phosphate (alpha-TCP) and tetracalcium phosphate (TTCP) respectively were chosen as basic compositions of phosphate bone cements. Other auxiliary materials such as hydroxyapatite (HAP), dicalcium phosphate dihydrate (DCPD), calcium carbonate (CaCO3), calcium oxide (CaO) and amorphous calcium silicate (CaSiO3) were added in the cements. Six kinds of composite bone cements were decided with 1.50 as their Ca/P ratio. Then the primary properties of them were studied. Ringer's simulated body fluid (SBF) tests were carried out for the samples. The changes of pH value in SBF and the compressive strength of the samples with the immersion time were studied. The results showed: the mixing liquid 0.25 M K2HPO4/KH2PO4 and amorphous CaSiO3 were effective for accelerating the setting of the cements; the initial setting time (It) was about 4-5.5 min and the final setting time (Ft) was about 18-19. 5 min. Amorphous calcium silicate can increase the compressive strength of the bone cements remarkably; the compressive strength of the alpha-TCP bone cement with the addition of suitable amount amorphous CaSiO3 reached 45.3 MPa after immersion in SBF for 14 days.
Chemical Engineering School, Dalian University of Technology, Dalian 116012, China.
Zhiqiang
Z
Wang
Jilin
J
Hu
Xiaolei
X
Liu
Xiaoxu
X
Chen
Bingling
B
Lü
D001843:Bone Cements / Q000138:chemical synthesis* / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength; D006801:Humans; D017640:Silicates / Q000737:chemistry*
D001843:Bone Cements; D017610:Calcium Compounds; D002130:Calcium Phosphates; D017640:Silicates; C485830:tetracalcium phosphate; C018392:tricalcium phosphate; C031293:calcium silicate