Combating psychosis in Parkinson's disease patients: the use of antipsychotic drugs.
Parkinson's disease (PD) patients commonly experience psychotic symptoms, with the most frequent manifestation being visual hallucinations. In PD, psychosis is predominantly drug induced and an important issue for clinicians to address as it increases the risk of nursing home placement as well as mortality. This review summarises the current knowledge regarding the clinical manifestations, pathophysiology and risk factors for drug-induced psychosis in patients with PD and focuses on treatment, especially with regard to the atypical antipsychotics.
Chou
Kelvin L
KL
Department of Clinical Neurosciences, Brown Medical School, Providence, Rhode Island, USA.
Fernandez
Hubert H
HH
D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010300:Parkinson Disease / Q000188:drug therapy* / Q000523:psychology; D011605:Psychoses, Substance-Induced / Q000188:drug therapy* / Q000523:psychology
D014150:Antipsychotic Agents