[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation].
We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions. The patient presented with mucoid anal adenocarcinoma. He was treated with preoperative neoadjuvant chemotherapy (5-FU and leucovorin) and external radiation therapy plus laparoscopy-assisted abdominoperineal amputation. Mucoid adenocarcinoma on chronic perianal fistula is an infrequent process. Late diagnosis is associated with a poor prognosis.
Servicio de Cirugía General y Aparato Digestivo, Hospital de Zumárraga, Zumárraga, Guipúzcoa, País Vasco, Spain.
Javier
J
Ibáñez
José M
JM
Erro
Francisca
F
Aranda
María Luz
ML
Almendral
Carla
C
Valenti
Miguel
M
Echenique-Elizondo
D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000628:therapy*; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001005:Anus Neoplasms / Q000150:complications* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002908:Chronic Disease; D003131:Combined Modality Therapy; D013505:Digestive System Surgical Procedures / Q000379:methods; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D010535:Laparoscopy; D002955:Leucovorin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010502:Perineum / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012003:Rectal Fistula / Q000150:complications*
D000964:Antimetabolites, Antineoplastic; D002955:Leucovorin; D005472:Fluorouracil