Clinico-microbiological profile and visual outcomes of post-traumatic endophthalmitis at a tertiary eye care center in South India.
OBJECTIVE
To analyze the clinical and microbiological characteristics of eyes with post-traumatic endophthalmitis and factors influencing the visual outcomes in these cases.


METHODS
We performed a retrospective chart analysis of the clinical and microbiological data of 97 consecutive patients with post-traumatic endophthalmitis presenting to a tertiary eye care hospital in South India.


RESULTS
Thirty-nine (40.2%) cases were culture-positive, gram-positive cocci (n=24/42, 57.1%) being the commonest isolates. Staphylococcus epidermidis and Pseudomonas aeuruginosa were the commonest single isolates (n=10; 23.8%). Majority of the organisms were sensitive to chloramphenicol (n=27) or ciprofloxacin (n=26). Susceptibility to vancomycin (n=3) and amikacin (n=4) was poor. Cases with negative cultures at presentation were more likely to have improvement in visual acuity compared with culture-positive cases (on multivariate analysis, OR: 3.2, 95% CI: 1.1, 9.0).


CONCLUSIONS
In this series of post-traumatic endophthalmitis, a high prevalence of resistance of the culture isolates to vancomycin and amikacin was observed.
Vedantham
Vasumathy
V
Aravind Eye Hospital and PG Institute of Ophthalmology, 1, Anna Nagar, Madurai, TamilNadu-625 020, India. drvasumathy@yahoo.com
Nirmalan
Praveen K
PK
Ramasamy
Kim
K
Prakash
Karthik
K
Namperumalsamy
Perumalsamy
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D009877:Endophthalmitis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D015818:Eye Infections, Bacterial / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D005131:Eye Injuries / Q000150:complications* / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology
D000900:Anti-Bacterial Agents