Preparation and encapsulation of highly fluorescent conjugated polymer nanoparticles.
A facile method has been developed to prepare aqueous dispersions of encapsulated conjugated polymer nanoparticles exhibiting high fluorescence brightness. Salient features of the nanoparticles include their small diameter and spherical morphology. Encapsulation of the nanoparticles with a silica shell reduces the rate of photooxidation and allows facile attachment of functional groups for subsequent bioconjugation and nanoparticle assembly. Functionalization of the nanoparticle with amine groups followed by the addition of Au nanoparticles resulted in the formation of nanoparticle assemblies, as evidenced by the efficient quenching of the conjugated polymer fluorescence by the Au nanoparticles.
Department of Chemistry, Center for Optical Materials Science and Engineering Technologies, Clemson University, Clemson, South Carolina 29634, USA.
Changfeng
C
Wu
Craig
C
Szymanski
Jason
J
McNeill
D005456:Fluorescent Dyes / Q000737:chemistry*; D005465:Fluorocarbon Polymers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010777:Photochemistry; D012822:Silicon Dioxide / Q000737:chemistry*
D005456:Fluorescent Dyes; D005465:Fluorocarbon Polymers; D006046:Gold; D012822:Silicon Dioxide