A kinetic study on Rh/binap-catalyzed 1,4-addition of phenylboronic acid to enones: negative nonlinear effect caused by predominant homochiral dimer contribution.
A kinetic study on the Rh/binap-catalyzed 1,4-addition of phenylboronic acid using reaction calorimetry revealed that the catalytically inactive dimeric hydroxorhodium complex [Rh(OH)((R)-binap)]2 (RR-4) is the resting state. A negative NLE in eeprod and an amplified reaction rate were predicted and observed in the present reaction system characterized by the preferential formation of homochiral dimer.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Asato
A
Kina
Hiroshi
H
Iwamura
Tamio
T
Hayashi