Treatment of unresectable malignant rhabdoid tumor of the orbit with tandem high-dose chemotherapy and gamma-knife radiosurgery.
Malignant rhabdoid tumor (MRT) is a rare and highly aggressive tumor that primarily occurs in very young children. We report here a patient with a primary MRT of the orbit who received tandem high-dose chemotherapy and gamma-knife radiosurgery. Although the tumor was not completely removed, and the initial chemotherapy failed, the patient achieved long-term survival after this modality of treatment. This approach may be one to be further considered in patients with MRT.
Department of Pediatrics, Tokushima University Hospital, Tokushima, Japan. hwatanabe@clin.med.tokushima-u.ac.jp
Hiroyoshi
H
Watanabe
Tsutomu
T
Watanabe
Michiya
M
Kaneko
Hiroko
H
Suzuya
Toshihiro
T
Onishi
Yasuhiro
Y
Okamoto
Hajime
H
Miyake
Kensaku
K
Yasuo
Takanori
T
Hirose
Shoji
S
Kagami
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D011237:Predictive Value of Tests; D011379:Prognosis; D016634:Radiosurgery; D018335:Rhabdoid Tumor / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome