[Clinical and immunological effect of vaccination against Haemophilus influenzae, type B, in children with disorders of the nervous system].
Observations on 277 children aged 3 months to 4 years with lesions of the nervous system, immunized with vaccine Act-HIB (Aventis Pasteur, France), were carried out in groups of children. The significant decrease of the level of Hib nasopharyngeal carrier state in 3.3 times and the decrease of total morbidity in acute infections of respiratory and ENT organs in 2.7 times occurred after immunization was revealed. The immunological effect of immunization on the level of protective titers against H. influenzae, type b, in children with organic CNS lesions in children was shown.
Kurtasova
L M
LM
Ruzaeva
L A
LA
Dvoekonko
A A
AA
Opeĭkina
N N
NN
Shakina
N A
NA
Iashchenko
S V
SV
Zarianko
G A
GA
Tret'iakova
V A
VA
Fedotova
N A
NA
D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000097:blood*; D016667:Bacterial Capsules; D002353:Carrier State / Q000276:immunology* / Q000517:prevention & control*; D002493:Central Nervous System Diseases / Q000150:complications / Q000276:immunology*; D002675:Child, Preschool; D006192:Haemophilus Infections / Q000150:complications / Q000276:immunology* / Q000517:prevention & control*; D018073:Haemophilus Vaccines / Q000008:administration & dosage*; D019741:Haemophilus influenzae type b / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage*; D012141:Respiratory Tract Infections / Q000150:complications / Q000276:immunology / Q000517:prevention & control; D012800:Siberia; D014611:Vaccination
D000907:Antibodies, Bacterial; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D011135:Polysaccharides, Bacterial