Celiac disease occurring in a patient with hypoparathyroidism and autoimmune thyroid disease.
Patients with an underlying autoimmune endocrine disorder are at an increased risk of developing other autoimmune diseases. We describe a patient with idiopathic autoimmune hypoparathyroidism who developed hyperthyroidism due to Graves disease and subsequently was diagnosed with celiac disease. Malabsorption of L-thyroxine was the only clue regarding the presence of celiac disease. This particular association of these three autoimmune disorders occurring in the same patient has not, to our knowledge, been previously reported. The presentation, investigations performed, and treatment provided are discussed and the literature pertaining to similar cases is reviewed.
Khandwala
Hasnain M
HM
Division of Endocrinology, University of Saskatchewan, Saskatoon, Canada. Hasnainkhan@yahoo.com
Chibbar
Rajni
R
Bedi
Anil
A
D000328:Adult; D001323:Autoantibodies / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D002446:Celiac Disease / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D004386:Duodenum / Q000473:pathology; D005260:Female; D005903:Gliadin / Q000276:immunology; D006111:Graves Disease / Q000150:complications* / Q000276:immunology; D006801:Humans; D007011:Hypoparathyroidism / Q000097:blood / Q000150:complications*; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D010281:Parathyroid Hormone / Q000097:blood; D013954:Thyroglobulin / Q000276:immunology; D011503:Transglutaminases / Q000276:immunology
D001323:Autoantibodies; D015415:Biomarkers; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D010281:Parathyroid Hormone; C006606:anti-thyroglobulin; D005903:Gliadin; D013954:Thyroglobulin; D011503:Transglutaminases