Congenital fibrous hamartoma of the knee.
A full-term male infant presented at birth with a hard swelling of the left knee. The lemon-sized lesion was fixed to the underlying knee muscles, while the overlying skin was stretched and shiny; there was no bruit. Radiography, sonography and MRI suggested a soft-tissue tumour. After surgical excision, histology showed the presence of fibrous and mesenchymal tissue, with mature adipose tissue. Fibrous hamartoma of infancy was diagnosed. Among soft-tissue tumours, fibrous hamartoma of infancy is a rare and benign lesion, occurring in the first 2 years of life. The tumour mainly affects the trunk, axilla, and upper extremities. This infant had unique involvement of the knee. The treatment of choice is local excision.
Neonatal Pathology Service, Department of Paediatrics, Institute G. Gaslini, University of Genoa, Largo G. Gaslini 5, 16147, Genoa, Italy.
Cesare
C
Arioni
Carlo
C
Bellini
Mauro
M
Oddone
Francesco Maria
FM
Risso
Fabio
F
Scopesi
Paolo
P
Nozza
Giovanni
G
Serra
Paolo
P
Tomà
D006222:Hamartoma / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D007717:Knee / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000175:diagnosis