[Antidiphtheria immunity in children after immunization with adsorbed DPT vaccine and ADPT-M toxoid].
Antidiphtheria immunity in children aged 3-15 years was evaluated, depending on their age, the vaccinal preparation chosen for immunization and the immunization schedule. Adsorbed DPT vaccine was shown to have a higher immunological activity in comparison with adsorbed DT toxoid with reduced antigen content. The relationship between the tension of antidiphtheria antitoxic immunity in children and the possibility of the formation of the clinical forms of diphtheria with different severity in the patients was established. Children aged 4-6 years were considered to be a group of high risk in diphtheria morbidity, as it was among the children of this group that toxic and subtoxic forms of diphtheria were most often registered (44.9 +/- 7.1% of the examinees); in addition, a high proportion of children seronegative to this infection (26,3 +/- 2.2%) was observed in this group.
Kharseeva
G G
GG
Moskalenko
E P
EP
Fedoruk
S I
SI
Inozemtseva
G A
GA
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004165:Diphtheria / Q000276:immunology* / Q000517:prevention & control*; D004168:Diphtheria Toxoid / Q000276:immunology*; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D012307:Risk Factors; D012426:Russia; D014611:Vaccination
D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine