Different degrees of right-to-left shunting predict migraine and stroke: data from 420 patients.
The authors analyzed the extent of right-to-left shunting in patients with migraine, patients with cryptogenic stroke, and controls. Patients with both migraine and stroke had larger shunts than did patients with migraine without stroke (p = 0.038), patients with no migraine with stroke (p = 0.007), and control patients (p < 0.0001). Patients with migraine have overall larger shunts than nonmigraineurs, particularly if they have had a stroke. Right-to-left shunting may be causally related to migraine and to the increased stroke risk of migraine.
ervizio di Neurologia, Ospedale S. Orsola FBF, Associazione Fatebenefratelli per la Ricerca (AFaR), Brescia, Italy. gpanzola@numerica.it
Gian Paolo
GP
Anzola
Eva
E
Morandi
Francesco
F
Casilli
Eustaquio
E
Onorato
D000328:Adult; D000368:Aged; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012189:Retrospective Studies; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016896:Treatment Outcome; D017585:Ultrasonography, Doppler, Transcranial