[The advance of research in electro-physiology and chip techniques for olfaction and gustation].
This paper introduces the new research achievement and progress of electro-physiology in olfaction and gustation. Classical implements such as patch-clamp or glass pipette are not appropriate in the dynamic detection of cellular signal transportation. In view of this, we have analyzed the feasibilities and challenges of olfactory or gustatory cell-based biosensors such as field effect transistor (FET) and light addressable potentiometric sensor (LAPS). Finally we present the research work carried our in out lab and a future prospective on the development in this field.
Xu
Ying
Y
Biosensors National Special Lab, Department of Biomedical Engineering, Zhejiang University. Hangzhou 310027, China.
Li
Yan
Y
Xu
Gaixia
G
Qin
Lifeng
L
Li
Rong
R
Ye
Xuesong
X
Wang
Ping
P
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004594:Electrophysiology / Q000379:methods; D006801:Humans; D046208:Microchip Analytical Procedures / Q000379:methods*; D012903:Smell / Q000502:physiology*; D013649:Taste / Q000502:physiology*