[Primary biliary cirrhosis and autoimmune hepatitis overlap syndrome. An early case].
A 21-year old asymptomatic woman had accidental report of increased transaminases. Serologic tests were negative, autoimmune profile was positive for anti-nuclear, antimitochondrial antibodies and rheumatoid factor. Histology of the liver biopsy showed severe necro-inflammatory activity both in biliary epithelium and in intralobular area, suggesting primary biliary cirrhosis/autoimmune hepatitis overlap syndrome.
Istituto di Medicina Interna, Geriatria e Gerontologia, Dipartimento di Medicina Clinica e Sperimentale, Azienda Ospedaliera-Universitaria S. Anna, Ferrara. bbsvcn@unife.it
Vincenzo
V
Abbasciano
Lucio
L
Trevisani
Filippo
F
Di Todaro
Cristina
C
Guglielmini
Andrea
A
Marzola
Sergio
S
Sartori
Andrea
A
Salemi
D000328:Adult; D000367:Age Factors; D001706:Biopsy; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D013577:Syndrome