Role of complement during experimental Candida infection in mice.
The role of complement during experimental Candida albicans infection was investigated in mice. It was found that complement-positive CF-1 mice, infected with the test organism, survived significantly longer than complement-deficient mice of the same strain. This implies the participation of the relatively late acting complement component in host defense mechanisms directed against this systemic mycotic infection.
Morelli
R
R
Department of Medical Microbiology, Stanford University, Stanford, California 94305.
Rosenberg
L T
LT