Human Protein Atlas charts a diverse terrain.
A complete set of high-quality antibodies against the human proteome would constitute a remarkable resource for the analysis of protein abundances in tissues, facilitating systematic protein expression profiling in health and disease. In two recent papers, Swedish researchers describe a concerted effort towards producing a 'Human Protein Atlas' by combining high-throughput antibody generation with immunohistochemical profiling of tissue microarrays.
Saviranta
Petri
P
Medical Biotechnology, VTT Technical Research Centre of Finland and University of Turku, Itäinen Pitkäkatu 4A, FIN-20520 Turku, Finland. petri.saviranta@vtt.fi
Kallioniemi
Olli
O
D003628:Database Management Systems; D030562:Databases, Protein; D006801:Humans; D020407:Internet; D008958:Models, Molecular; D009928:Organ Specificity; D020543:Proteome / Q000737:chemistry* / Q000276:immunology*; D040901:Proteomics / Q000379:methods*; D014584:User-Computer Interface
D020543:Proteome