Disruption of protein-protein interactions using nanoparticles: inhibition of cytochrome c peroxidase.
Functionalized gold nanoparticles bind selectively to cytochrome c or cytochrome c peroxidase and inhibit enzyme turnover.
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Halil
H
Bayraktar
Partha S
PS
Ghosh
Vincent M
VM
Rotello
Michael J
MJ
Knapp
D003578:Cytochrome-c Peroxidase / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D053758:Nanoparticles / Q000737:chemistry*; D011485:Protein Binding / Q000187:drug effects
D003578:Cytochrome-c Peroxidase