Does thrombolysis benefit patients with lacunar syndrome?
The efficacy of thrombolysis in clinical stroke subtypes is unclear. We compared the benefit of intravenous rt-PA in 11 patients with lacunar syndrome with that in 33 patients with a non-lacunar syndrome. Patients were matched by NIHSS score and time to treatment. Although no statistically significant differences were detected in outcome, the benefit was greater in the non- lacunar syndrome group.
Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain. dcocho@hsp.santpau.es
Dolores
D
Cocho
Roberto
R
Belvís
Joan
J
Martí-Fàbregas
Yolanda
Y
Bravo
Aitziber
A
Aleu
Javier
J
Pagonabarraga
Laura
L
Molina-Porcel
Jorge
J
Díaz-Manera
Luis
L
San Roman
María
M
Martínez-Lage
Alejandro
A
Martínez
Mireia
M
Moreno
Josep-Lluis
JL
Martí-Vilalta
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000175:diagnosis / Q000188:drug therapy*; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use; D012189:Retrospective Studies; D013577:Syndrome; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D016896:Treatment Outcome
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator