Optical coherence tomography in tamoxifen retinopathy.
Optical coherence tomography (OCT) is a non-invasive, transpupillary imaging technology that allows detailed analysis of the retinal structures. In a recent article, Gualino et al. reported that OCT revealed a foveolar cystoid space with focal disruption of the photoreceptors line that explains the irreversible loss of central vision in tamoxifen retinopathy. In addition to providing a better understanding of the pathogenesis of tamoxifen retinopathy, OCT screening is advisable in patients treated with tamoxifen over long periods in order to detect and prevent drug-induced retinal damage.
Martine
M
Mauget-Faÿsse
Mauget-Faÿsse
MF
Martine
Joël
J
Gambrelle
Gambrelle
G
Joël
Maddalena
M
Quaranta-El Maftouhi
Quaranta-El Maftouhi
QE
Maddalena
D000368:Aged; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D012160:Retina / Q000378:metabolism / Q000473:pathology; D012164:Retinal Diseases / Q000139:chemically induced* / Q000473:pathology; D012542:Scattering, Radiation; D013629:Tamoxifen / Q000009:adverse effects* / Q000494:pharmacology*; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*
D013629:Tamoxifen