Screening and industrial application of unique microbial reactions involved in nucleic acid and lipid metabolisms.
Bioprocesses, which involve biocatalysts for the production of useful compounds, are expected to become a leading player in green chemistry. The first step in bioprocess development is screening for useful biological reactions in the immense number of microorganisms with infinite diversity and versatility. This review introduces some examples of bioprocess development that started from process design stemming from the discovery of unique metabolic processes, reactions, and enzymes in microbial nucleic acid and lipid metabolisms.
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan. ogawa@kais.kyoto-u.ac.jp
Jun
J
Ogawa
Chee-Leong
CL
Soong
Shigenobu
S
Kishino
Qing-Shan
QS
Li
Nobuyuki
N
Horinouchi
Sakayu
S
Shimizu
D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism; D002384:Catalysis; D007218:Industrial Microbiology / Q000379:methods*; D050356:Lipid Metabolism; D009696:Nucleic Acids / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D000596:Amino Acids; D009696:Nucleic Acids