Managing sternal osteomyelitis with antibiotic bead implantation.
Early, aggressive debridement followed by closure with muscle flaps is thought to improve the resolution of deep sternal wound infection that occurs after sternotomy. However, persistently discharging sternal osteomyelitis remains difficult to resolve. We successfully treated 2 patients who developed deep sternal wound infection after cardiac surgery by combining one-stage debridement with implantation of gentamicin beads to fill up the evacuated bone marrow space. This approach provides a simple and effective solution for sternal osteomyelitis.
Department of Cardiovascular Surgery, Far-Eastern Memorial Hospital, 21, Sec 2, Nan-Ya S. Road, Pan-Chiao, Taipei 220, Taiwan.
Kuan-Ming
KM
Chiu
Tzu-Yu
TY
Lin
Shu-Hsun
SH
Chu
Cheng-Wei
CW
Lu
D000368:Aged; D001026:Coronary Artery Bypass; D003646:Debridement; D004343:Drug Implants; D005260:Female; D005839:Gentamicins; D006801:Humans; D008297:Male; D008768:Methylmethacrylates; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy* / Q000209:etiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology; D013249:Sternum; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000209:etiology; D013908:Thoracotomy / Q000009:adverse effects*
D004343:Drug Implants; D005839:Gentamicins; D008768:Methylmethacrylates; C030159:gentamicin-polymethylmethacrylate bead