Isolated bone marrow occurrence of classic Hodgkin's lymphoma in an HIV-negative patient.
Classic Hodgkin's Lymphoma is a disease usually characterized by lymph nodal presentation. Rare cases with extra-nodal first clinical manifestation may occur, and primary bone marrow involvement may be part of them: isolated bone marrow forms have been recently described in the context of HIV infection. We herein report a case of isolated bone marrow Hodgkin's Lymphoma occurrence in a HIV-negative, elderly patient. The impacts of such unusual Hodgkin's Lymphoma manifestation on clinical practice as well as the related diagnostic and therapeutic implications are discussed.
Ponzoni
Maurilio
M
Pathology Unit, Department of Oncology, San Raffaele H Scientific Institute, Milan, Italy. ponzoni.maurilio@hsr.it
Ciceri
Fabio
F
Crocchiolo
Roberto
R
Famoso
Graziana
G
Doglioni
Claudio
C
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D015658:HIV Infections / Q000175:diagnosis; D015497:HIV-1; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans