Decarboxylative Claisen condensation catalyzed by in vitro selected ribozymes.
The in vitro selection of RNAs catalyzing the decarboxylative Claisen condensation provides evidence for the synthesis of fatty acids, the building blocks of lipids and membranes, in the "RNA world".
Ryu
Youngha
Y
Department of Chemistry, Texas A&M University, College Station, TX 77843-3255, USA.
Kim
Kil-Joong
KJ
Roessner
Charles A
CA
Scott
A Ian
AI
D002384:Catalysis; D003653:Decarboxylation; D015394:Molecular Structure; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D016337:RNA, Catalytic / Q000378:metabolism*
D016337:RNA, Catalytic; D012313:RNA