Vital capacity and selected metabolic diseases in middle-aged Japanese men.
OBJECTIVE
To elucidate the association between vital capacity and the presence of selected metabolic diseases in middle-aged Japanese men.


METHODS
A cross-sectional analysis of the associations among forced vital capacity (FVC), static vital capacity as a percentage of that predicted (%VC) and the presence of metabolic diseases was performed.


RESULTS
In a univariate linear regression analysis, FVC and %VC were inversely associated with poor vegetable intake, cigarette smoking and body mass index, but not with physical activity or ethanol consumption. In a logistic regression analysis adjusted for lifestyle factors, body mass index and age, the odds ratios for the presence of metabolic disease per 0.54 L (1 SD) decrease in FVC were 1.24 (95% CI 1.03 to 1.50) for type II diabetes, 1.21 (95% CI 1.02 to 1.42) for hypertension, 1.34 (95% CI 1.11 to 1.63) for hypertriglyceridemia, 1.23 (95% CI 1.03 to 1.46) for high gamma-glutamyl transferase levels and 1.63 (95% CI 1.10 to 2.41) for an episode of cardiovascular disease. FVC did not correlate with hyperhomocysteinemia, hypercholesterolemia or high white blood cell count. Similar results were also obtained for the association between %VC and metabolic diseases.


CONCLUSIONS
A decrease in FVC or %VC was associated with the presence of some metabolic diseases. The association may partly explain the reported association between low FVC and cardiovascular disease.
Self-Defense Forces Central Hospital, Tokyo, Japan. hsakuta@msa.biglobe.ne.jp
H
H
Sakuta
Takashi
T
Suzuki
Hiroko
H
Yyasuda
Teizo
T
Ito
D000428:Alcohol Drinking; D001786:Blood Glucose; D001794:Blood Pressure; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007958:Leukocyte Count; D008019:Life Style; D016015:Logistic Models; D008297:Male; D008659:Metabolic Diseases / Q000097:blood; D008875:Middle Aged; D009043:Motor Activity; D016017:Odds Ratio; D012907:Smoking; D014280:Triglycerides / Q000097:blood; D014797:Vital Capacity; D005723:gamma-Glutamyltransferase / Q000097:blood
D001786:Blood Glucose; D014280:Triglycerides; D005723:gamma-Glutamyltransferase