Predictors of non-significant endoscopic findings in patients with suspected upper gastrointestinal tract hemorrhage.
OBJECTIVE
The objective of the present study was to determine pre-endoscopic predictive factors of nonsignificant endoscopic findings in patients with suspected upper gastrointestinal tract hemorrhage (UGIH).


METHODS
Medical records of 187 patients admitted with the primary diagnosis of UGIH were reviewed. Non-significant endoscopic findings were defined as "normal": "mild gastritis" or unspecified gastritis with a hospital stay of two days or less. Possible predictors of non-significant endoscopic findings included pertinent history, physical examination, nasogastric tube aspirate, routine laboratory findings, and units of infused packed red cells (PRC). Multiple logistic regression analysis was used to determine significant predictors.


RESULTS
Predictors of non-significant endoscopic findings included the absence of comorbid diseases (OR: 6.4; 95%CI: 3.0-13.6), higher platelet count (OR. 1.7 per 100,000 increase; 95%CI: 1.1-2.5) and less PRC infusion (OR: 1.9 per unit decrease; 95%CI: 1.3-2.7).


CONCLUSIONS
Patients with UGIH who may have a negative EGD can be identified prior to endoscopy.
Department of Surgery, Ramathibodi Hospital and Medical School, Mahidol University, Bangkok 10400, Thailand.
Preeda
P
Sumritpradit
Suwat
S
Tangkittimasak
Panuwat
P
Lertsithichai
D000208:Acute Disease; D000553:Ambulatory Care; D015897:Comorbidity; D003937:Diagnosis, Differential; D004636:Emergency Service, Hospital; D016145:Endoscopy, Digestive System / Q000706:statistics & numerical data*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000145:classification / Q000175:diagnosis*; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D020380:Needs Assessment; D011237:Predictive Value of Tests; D011300:Preoperative Care; D011379:Prognosis; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013785:Thailand