New indole N-oxide alkaloids from Evodia fargesii.
Three new indole N-oxide alkaloids, fargesine (5-hydroxy-12-methyl-10,11,12,13-tetrahydro-1 H-azepino[5,4,3-cd]indole N(12)-oxide, 1), plectocomine 12-methyl-5- O-beta-D-glucopyranoside N(12)-oxide (2), and bufotenine 5-O-beta-D-glucopyranoside N(12)-oxide (3), were isolated from the root and stem of Evodia fargesii Dode along with five known compounds. The structures of the new alkaloids were elucidated on the basis of spectroscopic analysis.
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, PR China.
Shi-Jin
SJ
Qu
Quan-Wen
QW
Liu
Chang-Heng
CH
Tan
Shan-Hao
SH
Jiang
Da-Yuan
DY
Zhu
D000470:Alkaloids / Q000737:chemistry; D032086:Evodia; D006801:Humans; D007211:Indoles / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots; D018547:Plant Stems
D000470:Alkaloids; D007211:Indoles; D010936:Plant Extracts