Combining continuous endotoxin apheresis and continuous hemodiafiltration in the treatment of patients with septic multiple organ dysfunction syndrome.
When septic multiple organ dysfunction syndrome (MODS) occurs as a result of endotoxemia, diverse chemical mediators are excessively produced, and the patient becomes seriously ill. Under such circumstances, it is difficult to improve the patient's condition by endotoxin apheresis alone and hemodiafiltration should be carried out to remove excessive chemical mediators. Series-parallel treatment combining continuous endotoxin apheresis and hemodiafiltration is recommended for patients with septic MODS.
Department of Emergency and Critical Care Medicine, Akita University School of Medicine, Akita, Japan.
Chikara
C
Yonekawa
Hajime
H
Nakae
Kimitaka
K
Tajimi
Yoshihiro
Y
Asanuma
D001781:Blood Component Removal; D004731:Endotoxins / Q000097:blood*; D017583:Hemodiafiltration; D006801:Humans; D009102:Multiple Organ Failure / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D011112:Polymyxin B / Q000627:therapeutic use; D018805:Sepsis / Q000150:complications*
D004731:Endotoxins; D011112:Polymyxin B