Congenital fibrous hamartoma of the knee.
A full-term male infant presented at birth with a hard swelling of the left knee. The lemon-sized lesion was fixed to the underlying knee muscles, while the overlying skin was stretched and shiny; there was no bruit. Radiography, sonography and MRI suggested a soft-tissue tumour. After surgical excision, histology showed the presence of fibrous and mesenchymal tissue, with mature adipose tissue. Fibrous hamartoma of infancy was diagnosed. Among soft-tissue tumours, fibrous hamartoma of infancy is a rare and benign lesion, occurring in the first 2 years of life. The tumour mainly affects the trunk, axilla, and upper extremities. This infant had unique involvement of the knee. The treatment of choice is local excision.
Arioni
Cesare
C
Neonatal Pathology Service, Department of Paediatrics, Institute G. Gaslini, University of Genoa, Largo G. Gaslini 5, 16147, Genoa, Italy.
Bellini
Carlo
C
Oddone
Mauro
M
Risso
Francesco Maria
FM
Scopesi
Fabio
F
Nozza
Paolo
P
Serra
Giovanni
G
Tomà
Paolo
P
D006222:Hamartoma / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D007717:Knee / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000175:diagnosis