[Pancreatic transplantation. Results of the Málaga group].
BACKGROUND
Pancreatic transplantation is currently the only therapeutic alternative able to restore normal blood glucose levels in diabetic patients. Moreover, this procedure can halt or even reverse diabetes-related complications. The aim of this study was to present our experience and the results of the first 4 years of a pancreatic transplantation program in our center.


METHODS
From February 2000 to June 2004, 43 pancreatic transplantations were performed in 42 recipients in the Carlos Haya Regional Hospital in Malaga (Spain). In all patients, the technique of enteric drainage of exocrine pancreatic secretions and systemic venous shunting of endocrine secretions (to the inferior vena cava) was used.


RESULTS
There were 37 (88.1%) simultaneous pancreas-kidney transplantations, 4 (9.5%) in patients with prior kidney transplantation and 1 retransplantation (2.4%). In all patients, glycosylated hemoglobin and C-peptide levels returned to normal. Patient and pancreatic graft survival were 91% and 84%, respectively, with a median follow-up of 19 months. The reintervation rate was 31%, with an overall rate of graft loss of 16%.


CONCLUSIONS
The results obtained in our series are similar to those reported for large series.
Servicio de Cirugía General, Digestiva y Trasplante de Organos Sólidos Abdominales, Hospital Regional Universitario Carlos Haya, Málaga, Spain. alfonso.navarro.sspa@juntadeandalucia.es
Alfonso
A
Navarro-Piñero
M Jesús
MJ
Castro-Santiago
José Manuel
JM
Aranda-Narváez
Mercedes
M
Cabello-Díaz
Eugenia
E
Sola-Moyano
B
B
López Rueda
José Antonio
JA
Pérez-Daga
César Pablo
CP
Ramírez-Plaza
Dolores
D
Burgos-Rodríguez
Miguel
M
González-Molina
Agustín
A
de la Fuente-Perucho
D000293:Adolescent; D000328:Adult; D003920:Diabetes Mellitus / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D013030:Spain