[Values of color Doppler flow imaging and imaging changes of breast fascia and ligament in differential diagnosis of small breast neoplasms].
OBJECTIVE
Color Doppler flow imaging (CDFI) has been widely applied to the diagnosis of breast neoplasms. But combined use of CDFI and imaging changes of breast fascia and ligament (superficial and deep fascia, and Cooper's ligament) on the differential diagnosis of small breast neoplasms (< or =2 cm) has rarely been reported. This study was to explore the value of combined use of CDFI and imaging changes of breast fascia and ligament in differential diagnosis of small breast neoplasms.


METHODS
CDFI was performed on 110 patients with small breast neoplasms. Among them, 52 cases were diagnosed to be benign by pathologic examination after surgery, while the rest 58 were malignant. The blood flow and Doppler image inside and around the breast lesions were analyzed. Four grades were classified according to blood flow imaging. The infiltration of breast fascia and ligament was also considered. The CDFI result was compared with that of pathologic examination.


RESULTS
The correct diagnosis rates of CDFI in diagnosing benign and malignant small breast neoplasms were 90.4% and 84.5%, respectively. The false-positive and false-negative rates of CDFI were 9.6% and 15.5%, respectively. There were obvious differences in blood flow grading, systolic maximum velocity (V(max)), resistance index (RI), and imaging changes of superficial, deep fascia and Cooper's ligament between benign and malignant small breast neoplasms.


CONCLUSIONS
Combination of CDFI with imaging changes of breast fascia and ligament is valuable in clinical diagnosis and differential diagnosis of small breast neoplasms.
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China. gzzeng@163.com
Hui
H
Zeng
Yan-Li
YL
Zhao
Yong
Y
Huang
Xi
X
Lin
Xiao-Yue
XY
Chen
An-Hua
AH
Li
D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D001940:Breast / Q000098:blood supply; D001943:Breast Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D018270:Carcinoma, Ductal, Breast / Q000098:blood supply / Q000000981:diagnostic imaging; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000098:blood supply / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005205:Fascia / Q000000981:diagnostic imaging*; D005260:Female; D018226:Fibroadenoma / Q000098:blood supply / Q000000981:diagnostic imaging*; D005348:Fibrocystic Breast Disease / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D008022:Ligaments / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D018300:Papilloma, Intraductal / Q000098:blood supply; D018615:Ultrasonography, Doppler, Color / Q000379:methods*; D016217:Ultrasonography, Mammary; D014655:Vascular Resistance