Low-Temperature-Adapted Influenza A2/AA/6/60 Virus Vaccine in Man.
Volunteers inoculated nasopharyngeally with liver A2/AA/6/60 virus grown in primary bovine kidney cell cultures at 25 C were asymptomatic but developed significant serum and respiratory secretory antibody responses. Viruses were not recovered from these volunteers who had a low or moderate level of prevaccination antibody titers.
Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201.
T
T
Kitayama
Y
Y
Togo
R B
RB
Hornick
W T
WT
Friedwald