Metastatic prostate carcinoma mimicking meningioma: case report and review of the literature.
BACKGROUND
Intracranial dural-based lesions can be due to benign or malignant processes. Imaging characteristics cannot always discern between different pathologic conditions. A thorough clinical evaluation may reveal likely diagnostic possibilities. However, in certain cases, the etiology of the underlying lesion may require biopsy or resection to appropriately treat the patient.


RESULTS
We report the case of a large dural-based adenocarcinoma of the prostate clinically and radiographically mimicking a meningioma. We review the history and physical evaluation of the patient and subsequent treatment and response. We discuss the implications of dural-based intracranial lesions in patients with prostate cancer and review the literature of dural metastases, including the pathogenesis, tumor types, and clinical presentations.


CONCLUSIONS
The differential diagnosis of dural-based lesions in the brain varies from incidental and benign to symptomatic and malignant. Careful vigilance in patients with a history of cancer and presenting with new symptoms or imaging evidence of dural-based lesions is critically important to provide timely intervention.
Neurological Surgery, Mayo Clinic Scottsdale, Mayo Clinic College of Medicine, Scottsdale, Arizona 85259, USA. lyons.mark2@mayo.edu
Mark K
MK
Lyons
Joseph F
JF
Drazkowski
William W
WW
Wong
Tom R
TR
Fitch
Kent D
KD
Nelson
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008579:Meningioma / Q000175:diagnosis*; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery