Severe pulmonary disease due to multisystemic eosinophilic epitheliotropic disease in a horse.
Multisystemic eosinophilic epitheliotropic disease was diagnosed histologically in a 17-year-old Quarter Horse intact mare that was presented with a chronic history of respiratory distress. At necropsy, the lungs were poorly collapsed and the pulmonary parenchyma contained innumerable, discrete, spherical nodules in a miliary pattern. A few similar nodules were scattered in the liver and the renal lymph nodes. Histologically, these nodules consisted of fibrosing eosinophilic granulomas. Based on histologic findings and the absence of an etiologic agent, a diagnosis of multisystemic eosinophilic epitheliotropic disease was made.
Department of Veterinary Pathobiology, McElroy Hall 250, Oklahoma State University, Stillwater, OK 74078-2007, USA. skuldee@okstate.edu
K
K
Singh
T C
TC
Holbrook
L L
LL
Gilliam
R J
RJ
Cruz
J
J
Duffy
A W
AW
Confer
D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D017681:Hypereosinophilic Syndrome / Q000473:pathology / Q000662:veterinary*; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000473:pathology / Q000662:veterinary*