Middle lobe syndrome as the pulmonary manifestation of primary Sjögren's syndrome.
Middle lobe syndrome - recurrent atelectasis and/or bronchiectasis involving the right middle lobe and/or lingula - has, up to now, not been reported as the pulmonary manifestation of primary Sjögren's syndrome. We describe a patient in whom lymphocytic bronchiolitis in the atelectatic lobes was proved histologically from two separate transbronchial biopsies. The atelectasis responded well to glucocorticoid treatment, suggesting that the peribronchiolar lymphocytic infiltrates may have played an important role in the development of middle lobe syndrome in this patient.
Taipei Veterans General Hospital, Taiwan.
Horng-An
HA
Chen
Shinn-Liang
SL
Lai
Wei-Kang
WK
Kwang
Juhn-Cherng
JC
Liu
Chun-Hsiung
CH
Chen
De-Feng
DF
Huang
D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D008878:Middle Lobe Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D011859:Radiography; D012008:Recurrence; D012859:Sjogren's Syndrome / Q000150:complications*; D016896:Treatment Outcome
D005938:Glucocorticoids; D011239:Prednisolone