Lithium-associated hypothyroidism and thyroid papillary carcinoma: a case report.
Ionizing radiation, some hereditary factors, and chronic thyroid-stimulating hormone elevation increases the risk of differentiated thyroid carcinoma. Lithium salts are used in the treatment of affective (mood) disorders as well as a variety of other psychiatric conditions. There have been occasional reports of hematologic and solid neoplasms associated with lithium use. We report a patient who developed hypothyroidism and subsequently, thyroid papillary carcinoma while on lithium treatment for bipolar affective disorder.
Department of Medical Oncology, Hacettepe University Institute of Oncology, Ankara, Turkey. saksoy07@yahoo.com
Sercan
S
Aksoy
Saadettin
S
Kilickap
Mustafa
M
Erman
D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D001714:Bipolar Disorder / Q000188:drug therapy; D002291:Carcinoma, Papillary / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000139:chemically induced* / Q000150:complications; D016651:Lithium Carbonate / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D013972:Thyrotropin / Q000097:blood
D000928:Antidepressive Agents; D016651:Lithium Carbonate; D013972:Thyrotropin