[Correlations of preoperative pulmonary function tests for esophageal cancer to postoperative acute respiratory distress syndrome].
OBJECTIVE
Acute respiratory distress syndrome (ARDS), a serious postoperative complication of esophageal cancer, has a high mortality rate. Preoperative pulmonary function affects treatment project selection and prognosis prediction. The correlation of preoperative pulmonary function of esophageal cancer to postoperative ARDS has seldom been reported. This study was to analyze their correlation to serve for clinical medicine.


METHODS
Clinical data of 1 488 esophageal cancer patients, received esophagectomy from 2000 to 2002 in our hospital, were retrospectively reviewed. The correlations of postoperative ARDS to 3 traditional parameters in pulmonary function test, including forced expiratory volume in the first one second (FEV1%), the ratio of FEV1 to forced vital capacity [(FEV1/FVC)%] and maximal voluntary ventilation (MVV%), and other factors, such as age, sex, operation pattern, preoperative cardiac function, early postoperative intensive care, were analyzed.


RESULTS
Of the 1,488 patients, 49 suffered postoperative ARDS. The occurrence of ARDS was negatively related to the interaction of FEV1%, (FEV1/FVC)%, MVV% and age (P=0.001, P=0.005, P=0.048). Of the 49 patients suffered severe preoperative lung function damage, 32 received intensive care right after operation, of whom 2 (6.2%) had ARDS; 5 (29.4%) of the remaining 17 had ARDS. Early postoperative intensive care significantly decreased the occurrence of ARDS (P<0.05).


CONCLUSIONS
Traditional pulmonary function test have some correlations to postoperative ARDS. Early intensive care is important to prevent ARDS after operation.
Intensive Care Unit, The Forth Affiliated Hospital, Hebei Medical University, Shijiazhuang, Hebei 050011, P. R. China. zxy1698@sohu.com
Li-Xia
LX
Liu
Zhen-Jie
ZJ
Hu
Chai
C
Zhao
D000328:Adult; D000368:Aged; D003422:Critical Care; D004938:Esophageal Neoplasms / Q000503:physiopathology / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008451:Maximal Voluntary Ventilation; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012128:Respiratory Distress Syndrome / Q000209:etiology*; D012129:Respiratory Function Tests; D012189:Retrospective Studies