Effect of anatomical fine structure on the flow of cerebrospinal fluid in the spinal subarachnoid space.
The lattice Boltzmann method is used to model oscillatory flow in the spinal subarachnoid space. The effect of obstacles such as trabeculae, nerve bundles, and ligaments on fluid velocity profiles appears to be small, when the flow is averaged over the length of a vertebra. Averaged fluid flow in complex models is little different from flow in corresponding elliptical annular cavities. However, the obstacles stir the flow locally and may be more significant in studies of tracer dispersion.
Sandia Laboratories, Department 6118, Albuquerque, NM 87185-0750, USA.
Harlan W
HW
Stockman
D000818:Animals; D001683:Biological Clocks / Q000502:physiology; D002555:Cerebrospinal Fluid / Q000502:physiology*; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology*; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D012212:Rheology / Q000379:methods; D013116:Spinal Cord / Q000502:physiology* / Q000648:ultrastructure*; D013346:Subarachnoid Space / Q000502:physiology* / Q000648:ultrastructure*