DNA replication fidelity: proofreading in trans.
Proofreading is the primary guardian of DNA polymerase fidelity. New work has revealed that polymerases with intrinsic proofreading activity may cooperate with non-proofreading polymerases to ensure faithful DNA replication.
Department of Pathology, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195, USA.
Tina M
TM
Albertson
Bradley D
BD
Preston
D000818:Animals; D004247:DNA / Q000378:metabolism*; D004261:DNA Replication / Q000502:physiology*; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism*; D005092:Exonucleases / Q000378:metabolism; D008957:Models, Genetic; D009154:Mutation
D004247:DNA; D004259:DNA-Directed DNA Polymerase; D005092:Exonucleases