[Manufacture and application of SL-2000 bone fatigue damage testing device].
Having manufactured the bone fatigue damage testing device SL-2000, we applied it to research on bone fatigue damage and on the bone microdamage which can indicate bone biomechanical property. According to the general principle of industry fatigue machine and bone fatigue test, the strength, frequency and times of loading, temperature and degree of wetness were controlled in the SL-2000 Device for making the experiment condition stable. After the fatigue damage to SD rats' vertebrae, the models of bone microdamage in SD rat were established. 0-200 N of strength, 0-10 Hz frequency, and 0-999999 times of loading, ambient temperature 50 degrees C experiment, and approximately 99% of the ambient degree of wetness could be adjusted continuously. Three kinds of microdamage such as microcrack, cross-hatch staining, and diffuse staining were observed in the SD rats' vertebrae fatigue damaged by the device. The microcrack density was 19.76+/-15.05 #/mm2, the microcrack length was 36. 74+/-11. 51 microm, and the area ratio of diffuse staining was 0.4117%. Therefore the device is suitable for bone fatigue damage test and for establishment of the model of bone microdamage.
Institute of Metabolism and Endocrinology, The Second Xiang-Ya Hospital, Central South University, Changsha 410011 China. dairuchun@yahoo.com.cn
Ruchun
R
Dai
Eryuan
E
Liao
Xianping
X
Wu
Chuan
C
Yang
Liping
L
Meng
D000818:Animals; D001696:Biomechanical Phenomena; D019245:Compressive Strength; D004867:Equipment Design; D015775:Fractures, Stress / Q000175:diagnosis* / Q000503:physiopathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D016103:Spinal Fractures / Q000175:diagnosis* / Q000503:physiopathology; D013131:Spine / Q000473:pathology*; D016474:Weight-Bearing