Effects of the LactoSorb bioabsorbable plates on the craniofacial development of rabbits: direct morphometric analysis using linear measurements.
The use of plates for the treatment of fractures can affect craniofacial bone development. This study investigated the effect of bioabsorbable plates and titanium microscrews on the growth of the craniofacial skeleton of rabbits (Oryctolagus cuniculus), in the neonatal period. A LactoSorb plate and PROMM titanium microscrews were positioned across the coronal suture in animals in the study group. In the control group, only PROMM titanium microscrews were attached to the cranium. Anteroposterior linear measurements were obtained using 3 different gauging devices: digital precision caliper, EKG caliper and nylon string. Frontal-nasal (FN) distances were statistically different between the left and right side when the digital caliper (P<or=0.01), EKG caliper (P<or=0.01) and nylon string (P<or=0.05) were used. Mean right-side FN distances in the control and study groups were significantly different (P<or=0.05) when measured with the EKG caliper. Normal neonatal craniofacial growth of rabbits was affected by the use of bioabsorbable plates in this study. Further studies should be conducted to investigate whether these plates affect growth in human beings.
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Graduate Program in Oral and Maxillofacial Surgery, Pontifícia Universidade Católica do Rio Grande do Sul, Av. Ipiranga 6681, CEP 90619-900, Porto Alegre, RS, Brazil.
Cardoso
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ES
Bourguignon Filho
A M
AM
Borges
H O I
HO
Heitz
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C
de Oliveira
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MG
D020341:Absorbable Implants; D000818:Animals; D000831:Animals, Newborn; D001672:Biocompatible Materials / Q000737:chemistry; D001860:Bone Plates; D001863:Bone Screws; D002508:Cephalometry / Q000295:instrumentation / Q000379:methods; D003393:Cranial Sutures / Q000254:growth & development / Q000601:surgery; D005624:Frontal Bone / Q000254:growth & development / Q000601:surgery; D019344:Lactic Acid / Q000737:chemistry; D008297:Male; D008445:Maxillofacial Development / Q000502:physiology*; D009666:Nose / Q000254:growth & development; D010294:Parietal Bone / Q000254:growth & development / Q000601:surgery; D011100:Polyglycolic Acid / Q000737:chemistry; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers / Q000737:chemistry; D011817:Rabbits; D012886:Skull / Q000254:growth & development*; D014025:Titanium / Q000737:chemistry
D001672:Biocompatible Materials; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; D014025:Titanium