Fluorescent-antibody marker for vaccine-induced rubella antibodies.
Tests with LLC-MK2 and BHK-21 cells showed that the fluorescent-antibody (FA) procedure can be used to differentiate antibodies resulting from natural infection and antibodies stimulated by rubella vaccine virus. Negative or weak FA reactions in LLC-MK2 cells and strong reactions in BHK-21 cells indicated antibody stimulated by the vaccine virus; strong reactions in both cell systems reflected naturally acquired immunity.
Department of Epidemiology, The University of Michigan School of Public Health, Ann Arbor, Michigan 48104.
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Brown
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O'leary