Comparison of plasma and leukocyte vitamin C status between asthmatic and healthy subjects.
In a case-control study the vitamin C status of 50 adults with chronic controlled asthma was compared with that of 50 randomly selected healthy controls. Vitamin C intake was assessed by 3-day dietary recall, and plasma and leukocyte vitamin C concentrations were measured colorimetrically. A positive significant correlation was found between plasma vitamin C and dietary vitamin C intake. Plasma and leukocyte vitamin C levels were significantly lower in the asthma group. Plasma vitamin C was deficient (< 0.4 mg/dL) in significantly more patients than controls (38.0% versus 0%) and leukocyte vitamin C (< 20 microg/10(8) leukocytes) was deficient in 92.0% of asthmatics versus 8.0% of controls. A significant association was observed between duration of asthma and plasma vitamin C level.
Department of Nutrition, School of Health, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran. farzadshidfar@yahoo.com
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Shidfar
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Baghai
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Keshavarz
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Ameri
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Shidfar
D000328:Adult; D001205:Ascorbic Acid / Q000032:analysis / Q000097:blood; D001206:Ascorbic Acid Deficiency / Q000097:blood / Q000150:complications / Q000453:epidemiology; D001249:Asthma / Q000453:epidemiology / Q000209:etiology; D001827:Body Height; D001835:Body Weight; D016022:Case-Control Studies; D015984:Causality; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003124:Colorimetry; D015897:Comorbidity; D002149:Energy Intake; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D007962:Leukocytes / Q000737:chemistry*; D008297:Male; D018673:Nutrition Policy; D009749:Nutrition Surveys; D011159:Population Surveillance; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D013997:Time Factors
D001205:Ascorbic Acid