PET/CT following intensity-modulated radiation therapy for primary lung tumor in a dog.
A primary lung tumor in a dog treated with intensity-modulated radiation therapy was imaged approximately 6 weeks and 1-year posttreatment with combined positron emission tomography (PET) and computed tomography, utilizing the radiotracers 18F-fluorodeoxyglucose and 18F-fluorothymidine. These two tracers allowed discrimination of tumor from inflammation, and demonstrated spread of tumor along airways over time after treatment. Fusion of functional imaging with anatomic imaging is a useful tool, particularly in the field of oncology, with the potential for PET markers that delineate tumor from normal or reactive tissue, and potential or actual response to therapy.
Ballegeer
Elizabeth A
EA
Department of Surgical Sciences, University of Wisconsin, Madison, WI 53706, USA. ballegeer@svm.vetmed.wisc.edu
Forrest
Lisa J
LJ
Jeraj
Robert
R
Mackie
T Rockwell
TR
Nickles
R Jerome
RJ
D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000532:radiotherapy; D004285:Dogs; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D008175:Lung Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D049268:Positron-Emission Tomography / Q000662:veterinary; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000662:veterinary
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18