Revisiting the peritoneal dialysis dose.
The question of the minimum dose for adequate peritoneal dialysis has been settled following the publication of two randomized controlled studies and a number of nonrandomized studies. This review summarizes these studies, concluding that these studies support a weekly total Kt/V of 1.7 as the minimum dose, with careful observation for symptoms or signs of uremia and adjustment of the clearance as indicated.
WellBound, Inc., Mountain View, California 94041, USA. moranj@wellbound.com
John
J
Moran
Ricardo
R
Correa-Rotter
D002986:Clinical Trials as Topic; D015314:Dialysis Solutions / Q000008:administration & dosage*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008657:Metabolic Clearance Rate; D010530:Peritoneal Dialysis / Q000379:methods*; D014508:Urea / Q000097:blood
D015314:Dialysis Solutions; D014508:Urea