Quantification of left ventricular volumes from cardiac cine MRI using active contour model combined with gradient vector flow.
We investigated the feasibility of combining the active contour model with gradient vector flow (Snakes-GVF) to estimate left ventricular (LV) volumes from cardiac cine magnetic resonance imaging (MRI). MRI data were acquired from 27 patients, including 14 adults (9 men, 5 women, 55.0+/-23.3 years) and 13 children (10 boys, 3 girls, 2.7+/-2.1 years) using Gyroscan Intera (1.5 Tesla, Philips Medical Systems). LV volumes were calculated by adding the areas surrounded by the contour extracted by Snakes-GVF and compared with volumes estimated by manual tracing. Those estimated by Snakes-GVF [y (mL)] correlated well with those estimated by manual tracing [x (mL)]. In adult cases, the regression equation and correlation coefficient were y=1.008x - 0.517 and 0.996, respectively. In pediatric cases, they were y=1.174x - 2.542 and 0.992, respectively. In conclusion, Snakes-GVF is a powerful and useful tool for quantifying LV volumes using cardiac MRI.
Department of Medical Physics and Engineering, Division of Medical Technology and Science, Graduate School of Medicine, Osaka University, Japan.
Nobuyoshi
N
Tanki
Kenya
K
Murase
Masayuki
M
Kumashiro
Risa
R
Momoi
Xiaomei
X
Yang
Takashi
T
Tabuchi
Masako
M
Nagayama
Yuji
Y
Watanabe
D002306:Cardiac Volume / Q000502:physiology; D002675:Child, Preschool; D005240:Feasibility Studies; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume; D016276:Ventricular Function