The impact of microwave-assisted organic synthesis in drug discovery.
Microwave-assisted organic synthesis has revolutionized organic synthesis. Small molecules can be built in a fraction of the time required by classical thermal methods. As a result, this technique has rapidly gained acceptance as a valuable tool for accelerating drug discovery and development processes. This article outlines the basic principles behind microwave technology and summarizes recent trends and areas in drug discovery where this technology has made an impact.
Mavandadi
Farah
F
Biotage LLC, Charlottesville, VA 22911, USA. farah.mavandadi@biotage.com
Pilotti
Ake
A
D002625:Chemistry, Organic / Q000295:instrumentation / Q000379:methods; D015195:Drug Design; D008872:Microwaves; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*
D004364:Pharmaceutical Preparations