Development of gastric slow waves and effects of feeding in pre-term and full-term infants.
The aims of this study were to investigate the difference in developmental process of gastric slow waves and the effects of feeding in pre-term and full-term infants. Twenty-six pre-term and 31 full-term infants were enrolled in the study. Gastric myoelectrical activity was recorded using electrogastrography (EGG) from birth to month 6. An increase in the % of 2-4 cpm slow waves was noted in both pre-term (P < 0.01) and full-term infants (P < 0.04) from birth to month 4. The pre-term infants showed a reduced dominant EGG power at certain points of the study. (3) Breast or formula feeding resulted in no difference in the EGG in the full-term infants and showed a difference in the postprandial dominant power of the EGG in the pre-term infants only at month 2 after birth (P < 0.05) but not at other times. The gastric slow wave in pre-term infants is of a significantly reduced amplitude but similar rhythmicity. The method of feeding has no effects on the EGG in full-term infants and minimal effects (may be of non-clinical significance) on the EGG in pre-term infants as the difference was noted only at one time point during the 6-month follow-up study.
Division of Gastroenterology, University of Texas Medical Branch at Galveston, 77555, USA.
J
J
Zhang
H
H
Ouyang
H B
HB
Zhu
H
H
Zhu
X
X
Lin
E
E
Co
J
J
Hayes
J D Z
JD
Chen
D001903:Bottle Feeding; D001942:Breast Feeding; D004594:Electrophysiology; D005260:Female; D005746:Gastric Emptying; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D008297:Male; D013270:Stomach / Q000254:growth & development* / Q000502:physiology*