Comparison of biomechanical properties of alloderm and enduragen as static facial sling biomaterials.
BACKGROUND
Static slings are one of the most commonly used surgical rehabilitation methods in the management of chronic facial paralysis. Acellular human cadaveric dermis (Alloderm; Life Cell Corp., Branchburg, NJ) is used for this purpose; however, it has variable stretching properties that may necessitate additional "tuning-up" procedure(s). Acellular porcine dermis (Enduragen; Tissue Sciences Laboratories, plc., Aldershot, U.K.) was recently introduced as a biologic implant and it is compositionally similar to Alloderm. However, no data currently exist regarding its biomechanical properties and potential use as an alternative implant to Alloderm in static facial sling procedures.


OBJECTIVE
The objective of this study was to compare the biomechanical properties of Alloderm and Enduragen for static facial sling procedures in the management of the paralytic face.


METHODS
This study consisted of an in vitro prospective study in an academic medical research setting.


METHODS
Same size and thickness Alloderm and Enduragen samples were tested with MTS 858 Bionix materials test system for load-to-failure, displacement under increasing and constant stress, and stiffness.


RESULTS
Enduragen showed significantly less elongation under increasing stress and at the beginning of constant stress. Load-to-failure and stiffness were significantly higher in Alloderm; however, both biomaterials have adequate stiffness and load-to-failure for a static facial sling procedure.


CONCLUSIONS
Enduragen may serve as another potential static facial sling material, because it stretches significantly less than Alloderm under stress. Clinical experience is needed with Enduragen to determine its potential use as a static facial sling material.
Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, John McClellan VA Hospital, Little Rock, Arkansas 72205, USA. vuralemrea@uams.edu
Emre
E
Vural
Nathan
N
McLaughlin
William R
WR
Hogue
Larry J
LJ
Suva
D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D003094:Collagen; D020405:Dermis / Q000502:physiology* / Q000637:transplantation; D005158:Facial Paralysis / Q000601:surgery; D006801:Humans; D066298:In Vitro Techniques; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods; D016038:Skin Transplantation / Q000502:physiology*; D017768:Skin, Artificial; D013314:Stress, Mechanical; D014183:Transplantation, Heterologous
C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen