[Assessment of global left ventricular function with multi-slice spiral computed tomography].
OBJECTIVE
To investigate the value of multi-slice spiral computed tomography (MSCT) in the determination of global left ventricular function.


METHODS
Twenty-nine patients with confirmed or suspected coronary heart diseases were imaged with a contrast-enhanced retrospective electrocardiogram (ECG) -gated technique on a 64-slice spiral CT scanner. The data sets were reconstructed at both end-diastolic and end-systolic phases in order to measure left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left ventricular stroke volume (LVSV), and left ventricular ejection fraction (LVEF). The results were compared with corresponding values obtained from conventional left ventriculography (LVG).


RESULTS
LVEDV, LVESV, LVSV, and LVEF obtained with 64-slice spiral CT were significantly correlated with the LVG data (r = 0. 887-0.956, P < 0.001). According to the Bland-Altman approach, the mean differences for LVEDV, LVESV, LVSV, and LVEF were -2.3 ml, 4.1 ml, -6.4 ml, and - 3.5%, respectively. The limits of agreement for LVEDV, LVESV, LVSV, and LVEF were -27.2-22.4 ml, -10.2-18.4 ml, -26.4-13.6 ml, and -9.8%-3.0%, respectively.


CONCLUSIONS
MSCT has clinically acceptable agreement with LVG for the quantification of global left ventricular function.
Song
Lan
L
Department of Radiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Jin
Zheng-yu
ZY
Wang
Yi-ning
YN
Kong
Ling-yan
LY
Zhang
Zhu-hua
ZH
Zhang
Shu-yang
SY
Zhang
Li-ren
LR
Wang
Yun
Y
Zhao
Wen-min
WM
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000379:methods*; D016277:Ventricular Function, Left