Diabetes in overweight pediatric patients.
Diabetes mellitus (DM) is a growing problem among youth. Although type 1 (insulin-dependent) DM is a disease typically diagnosed during childhood or adolescence, estimates indicate that < or = 45% of new diabetes cases in children are type 2. Children with new-onset type 2 DM are often overweight, aged 10 years or older, have a family history of the disease, and are members of a racial/ethnic minority group. DM treatment has progressed greatly in recent decades. Inadequate therapy, urine testing, glycosylated hemoglobin levels of >10%, and high rates of diabetic complications that were common in the past have yielded to more effective treatments, accurate monitoring, and better outcomes. Insulin pumps and insulin analogues represent promising new avenues that have enhanced convenience, cost-effectiveness, patient satisfaction, and metabolic control of childhood DM.
Department of Pediatrics and General Clinical Research Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA. william.tamborlane@yale.edu
William V
WV
Tamborlane
D000293:Adolescent; D000367:Age Factors; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000188:drug therapy*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D050177:Overweight
D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin