The real radical generator other than main-product hydroperoxide in lipid autoxidation.
The theory of initiation in lipid autoxidation, which deals with the supply of radicals to the chain reaction, has not been substantively advanced for several decades. Most researchers have long assumed a mechanism of initiation in which main-product hydroperoxide is centrally responsible for autocatalytic radical generation. However, this paper, in which we investigate autoxidizing methyl linoleate, presents decisive evidence against such an assumption: Autoxidation-accelerating activity under mild conditions was not found in the chromatographically separated main-product hydroperoxide fraction but was found in other fractions; and highly active substances with structures containing a peroxide-linked dimer with two hydroperoxy groups were actually obtained.
Morita
Makio
M
Department of Health and Nutrition, Niigata University of Health and Welfare, 950-3198 Niigata City, Japan.
Tokita
Masako
M
D001894:Borohydrides / Q000737:chemistry; D005609:Free Radicals; D008401:Gas Chromatography-Mass Spectrometry; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry*; D010084:Oxidation-Reduction
D001894:Borohydrides; D005609:Free Radicals; D008055:Lipids; C025364:sodium borohydride; D006861:Hydrogen Peroxide