Cytochrome P450 2D6 dependent metabolization of risperidone is inhibited by melperone.
Michael D
MD
Köhnke
Ulrich
U
Lutz
Gerlinde
G
Wiatr
Frank
F
Schwärzler
Bastian
B
Weller
Klaus
K
Schott
Gerhard
G
Buchkremer
D000328:Adult; D002090:Butyrophenones / Q000494:pharmacology*; D065690:Cytochrome P-450 CYP2D6 Inhibitors; D006801:Humans; D008297:Male; D018967:Risperidone / Q000378:metabolism*; D012559:Schizophrenia / Q000188:drug therapy; D012892:Sleep Deprivation / Q000188:drug therapy
D002090:Butyrophenones; D065690:Cytochrome P-450 CYP2D6 Inhibitors; C008522:metylperon; D018967:Risperidone