Endometriosis in patients with chronic pelvic pain: is staging predictive of the efficacy of laparoscopic surgery in pain relief?
OBJECTIVE
Endometriosis is considered an important cause of chronic pelvic pain. Despite its high prevalence, controversy still exists regarding the true association between the extent of endometriosis and the severity of symptoms. We conducted this prospective study to investigate the association between the stage of endometriosis and type and severity of pain, and to evaluate the efficacy of laparoscopic surgery in pain relief.


METHODS
Ninety-five patients complaining of chronic pain were diagnosed with endometriosis and were treated with laparoscopic surgery. The severity of pain was assessed in patients with an endometriosis AFS (American Fertility Society) score less than 16 (group 1) and those with an AFS score greater than or equal to 16 (group 2), preoperatively and 6 months after surgery, using a visual pain scale. Any reduction in pain scores by 2 points or more was considered to be an improvement.


RESULTS
Dysmenorrhea and deep dyspareunia, were significantly more frequent in patients of group 2. Preoperative pain scores were significantly higher for dysmenorrhea (p = 0.0022) and deep dyspareunia (p < 0.0001) but not for non-menstrual pain in group 2. Deep dyspareunia was correlated with the presence of dense pelvic adhesions. After surgery, dysmenorrhea improved in 43% of cases in group 1, vs. 66% of cases in group 2 (p = 0.0037). For deep dyspareunia, improvement was reported by 33% in group 1, vs. 67% in group 2 (p = 0.074). Improvement in non-menstrual pain was not significantly different between the two groups (67% vs. 56%).


CONCLUSIONS
Advanced endometriosis is more frequently related to dysmenorrhea and deep dypareunia in comparison to early disease. Laparoscopic surgery may offer relief or improvement in the majority of patients with endometriosis and chronic pelvic pain. Cases with advanced disease seem to benefit the most.
First Department of Obstetrics and Gynecology, University of Athens, Alexandra Maternity Hospital, Athens, Greece.
Spyros
S
Milingos
Athanasios
A
Protopapas
George
G
Kallipolitis
Petros
P
Drakakis
Dimitrios
D
Loutradis
Anthoula
A
Liapi
Aris
A
Antsaklis
D002908:Chronic Disease; D004412:Dysmenorrhea / Q000175:diagnosis / Q000209:etiology; D004414:Dyspareunia / Q000175:diagnosis / Q000209:etiology; D004715:Endometriosis / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010147:Pain Measurement; D017699:Pelvic Pain / Q000209:etiology*; D011446:Prospective Studies; D016896:Treatment Outcome