[Surviving sepsis: where we are today].
The mortality induced by severe sepsis and septic shock remains very elevated despite progress in diagnosis and treatment. All the experts in the field consider that further progress is possible with better and more prompt use of the treatments now available. The "Surviving Sepsis" campaign reviews the diverse treatments that can be used and the best ways to prescribe them. It also proposes two bundles of objectives to be completed systematically for all patients: the first within the first 6 hours, the second between the sixth and 24th hour. Encouraging results show that applying these therapeutic principles can reduce mortality by 30% (relative percentage) compared with a treatment without specific objectives.
Leone
Marc
M
Département d'Anesthésie-Réanimation et Centre de Traumatologie, Hôpital Nord, bd Pierre Dramard, Marseille.
Vallet
Benoît
B
Martin
Claude
C
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D006875:Hydrotherapy / Q000379:methods; D020896:Hypovolemia / Q000209:etiology / Q000628:therapy; D017410:Practice Guidelines as Topic; D018805:Sepsis / Q000401:mortality / Q000628:therapy*; D012772:Shock, Septic / Q000401:mortality / Q000628:therapy; D017741:Survivors; D014667:Vasopressins / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D014667:Vasopressins