Technical feasibility and biocompatibility of a newly designed separating stent-graft in the normal canine aorta.
OBJECTIVE
The objectives of this study were to assess the performance of a newly designed separating stent-graft system with respect to the technical feasibility of transfemoral deployment, the maintenance of vessel patency, and stent deformity due to mechanical defects; and to evaluate its in vivo healing characteristics, including thrombus formation, and endothelial covering of the stent-graft when placed in the normal aorta of a canine model.


CONCLUSIONS
The newly designed separating stent-graft allowed accurate deployment without migration. This animal study also provided an opportunity to examine the healing process associated with an ultrathin polyester fabric nitinol stent and showed predictable healing characteristics in the normal thoracic aorta in this canine model.
Department of Radiology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.
Young-Cheol
YC
Weon
Sung-Gwon
SG
Kang
Jin Wook
JW
Chung
Young Il
YI
Kim
Jae Hyung
JH
Park
Do Yun
DY
Lee
D000818:Animals; D001013:Aorta, Thoracic / Q000601:surgery*; D004285:Dogs; D004867:Equipment Design; D005240:Feasibility Studies; D008297:Male; D008422:Materials Testing; D015607:Stents