One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines.
Novel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various alpha,beta-unsaturated compounds 2 and alpha-ketoalkynes 8 in excellent yields.
Department of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, India. dr_dprajapati2003@yahoo.co.uk
Dipak
D
Prajapati
Partha P
PP
Baruah
Baikuntha J
BJ
Gogoi
Jagir S
JS
Sandhu