Assigning exposure to pesticides and solvents from self-reports collected by a computer assisted personal interview and expert assessment of job codes: the UK Adult Brain Tumour Study.
OBJECTIVE
To compare assignment of occupational pesticide and solvent exposure using self-reported data collected by a computer assisted personal interview (CAPI) with exposure based on expert assessment of job codes. To discuss the advantages and disadvantages of using a CAPI to collect individual occupational exposure data.


METHODS
Between 2001 and 2004, 1495 participants were interviewed using a CAPI for a case-control study of adult brain tumours and acoustic neuromas. Two types of occupational data were collected: (1) a full history, including job title from which a job code was assigned from the Standard Occupational Classification; and (2) specific details on pesticide and solvent exposure reported by participants. Study members' experiences of using the CAPI were recorded and advantages and disadvantages summarised.


RESULTS
Of 7192 jobs recorded, the prevalence of self-reported exposure was 1.3% for pesticides and 11.5% for solvents. Comparing this with exposure expertly assessed from job titles showed 53.6% and 45.8% concordance for pesticides and solvents respectively. Advantages of the CAPI include no data entry stage, automatic input validation, and a reduction in interviewer bias. Disadvantages include an adverse effect on study implementation as a consequence of resources required for programming and difficulties encountered with data management prior to analysis.


CONCLUSIONS
Different methods of exposure assessment derive different exposure levels for pesticide and solvent exposure at work. Agreement between self-reported and expert assessment of exposure was greater for pesticides compared to solvents. The advantages of using a CAPI for the collection of complex data outweigh the disadvantages for interviewers and data quality but using such a method requires extra resources at the study outset.
Centre for Epidemiology and Biostatistics, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK. s.j.hepworth@leeds.ac.uk
S J
SJ
Hepworth
A
A
Bolton
R C
RC
Parslow
M
M
van Tongeren
K R
KR
Muir
P A
PA
McKinney
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology; D016022:Case-Control Studies; D003625:Data Collection / Q000379:methods* / Q000592:standards; D004739:England / Q000453:epidemiology; D005260:Female; D005910:Glioma / Q000453:epidemiology; D006801:Humans; D007407:Interviews as Topic / Q000379:methods; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000453:epidemiology; D016273:Occupational Exposure / Q000032:analysis*; D016272:Occupational Health; D010575:Pesticides / Q000032:analysis*; D015203:Reproducibility of Results; D012650:Self Disclosure; D012997:Solvents / Q000032:analysis*; D011795:Surveys and Questionnaires
D010575:Pesticides; D012997:Solvents