[Clinical observation on effect of jieguxujin granule in promoting union of fracture].
OBJECTIVE
To study the clinical effect of Jieguxujin granule (JGXJG) on fracture and its effect on serum content of calcitonin gene related peptide (CGRP).


METHODS
Four hundred patients with fracture were randomly divided into 2 groups, the JGXJG treated group and the control group treated with Sanqi tablet (SQT). Serum CGRP was tested with radioimmunoassay once every 3 days for 5 times, and X-ray examination was taken once each week for 10 weeks.


RESULTS
The healing time of fracture and osteotylus forming time in the JGXJG group was shorter than those in the SQT group significantly (P < 0.005). Serum CGRP content in JGXJG group was higher remarkably (P < 0.05, P < 0.01).


CONCLUSIONS
JGXJG showed evident effect in promoting union of fracture healing, it could also increase the CGRP content in serum.
Wenzhou Medical College, Zhejiang Province 325035. zxnp@yahoo.com
Teng
T
Zhou
Xiang-dong
XD
Chu
Xiao-yan
XY
Zhang
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015740:Calcitonin Gene-Related Peptide / Q000097:blood*; D002648:Child; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005264:Femoral Fractures / Q000188:drug therapy*; D017102:Fracture Healing / Q000187:drug effects*; D050723:Fractures, Bone / Q000188:drug therapy*; D006801:Humans; D006810:Humeral Fractures / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D013978:Tibial Fractures / Q000188:drug therapy
D004365:Drugs, Chinese Herbal; D015740:Calcitonin Gene-Related Peptide