Movement planning deficits in schizophrenia: failure to inhibit automatic response tendencies.
BACKGROUND
Explicit planning deficits have been reported frequently in patients with schizophrenia. This study addressed the question whether these patients would already encounter difficulties in a more "implicit" process of planning an optimal sequence of movements in simple actions.


METHODS
Twenty patients with schizophrenia and 20 controls participated in the study. The motor tasks consisted of copying simple line drawings in which the planning of a movement sequence was taxed along various dimensions. In the first task the number of line elements varied between one and two, and the two-line figures differed with respect to the ease with which the so-called graphic production rules could be applied. In the second task the spatial position of the drawing varied between an easy centre position and a somewhat more difficult corner location. In the third task, subjects were asked to start copying either at a preferred or at a less preferred starting point.


RESULTS
The results showed that the patients did not encounter planning difficulties while copying the one- or two-segment patterns. However, the variations in the spatial conditions and starting point did affect the patients' performance more than that of the controls. Whereas the patients with higher negative symptom scores tended to be slower when they were forced to start drawing at a particular point, the patients predominantly exhibiting features of disorganisation proved to be faster in this condition.


CONCLUSIONS
The findings suggest a fairly intact initiation of simple movement sequences in patients with schizophrenia, but difficulties in inhibiting automatic response tendencies. It is concluded that this inhibition failure may play an important role in the planning difficulties these patients experience.
Jogems-Kosterman
Bea J M
BJ
Institute of Mental Health Care, Brabant, The Netherlands. bjm.jogems@ggzoostbrabant.nl
Hulstijn
Wouter
W
Wezenberg
Elke
E
van Hoof
Jacques J M
JJ
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology*; D012018:Reflex / Q000502:physiology*; D012565:Schizophrenic Psychology; D013028:Space Perception / Q000502:physiology