Cerebral circulation insufficiency - correlation of CTA-visualized atherosclerotic lesions in extra- and intracranial arteries.
BACKGROUND
To analyze the co-occurrence of atherosclerotic lesions in CT angiograms of extra and intracranial arteries in patients with cerebral circulation insufficiency.


METHODS
Extra-and intracranial CTA was performed in 70 patients with symptoms of cerebral circulation insufficiency. Co-occurrence of atherosclerotic lesions at both levels and correlation between the degree of atherosclerosis and sex, age, and clinical symptoms were evaluated. Intracranial CTA results were compared to those of the control group, which consisted of 34 subjects asymptomatic of cerebral circulation insufficiency. The usefulness of various data reconstruction techniques (MIP and MPR vs. MIP only) for the evaluation of intracranial stenosis was subjected to independent analysis by two radiologists.


RESULTS
Concomitant occurrence of extra-and intracranial lesions was diagnosed in 56% of patients examined. A statistically significant correlation was found between the degree of stenosis at both levels under consideration (chi2=81.452; p<0.00001; contingency coefficient CC=0.733). A significant correlation was found between the development of clinical symptoms and the severity of extra and intracranial stenosis. The consistency between % representation of CTA-detected intracranial carotid stenosis, as independently analyzed by two radiologists, was higher in combined MIP &MPR than in MIP only (correlation coefficient R=0.9924, p<0.00001).


CONCLUSIONS
There was a statistically significant correlation found between extra-and intracranial arterial stenosis in patients with symptoms of cerebral circulation insufficiency indicating that cervical and cerebral stenosis tend to occur concomitantly. Combination of MIP & MPR seemed the optimum CTA post-processing technique when evaluating the intracranial arteries.
Division of Diagnostic Imaging, Radiology Department, Medical University of Silesia, Katowice, Poland. kgruszczynska@poczta.onet.pl
Katarzyna
K
Gruszczyńska
Jan
J
Baron
Zbigniew
Z
Zieliński
Jerzy
J
Walecki
Jan
J
Gniadek
Krzysztof
K
Czernicki
D000328:Adult; D000368:Aged; D050197:Atherosclerosis / Q000150:complications / Q000000981:diagnostic imaging*; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging; D002545:Brain Ischemia / Q000150:complications / Q000000981:diagnostic imaging*; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D002533:Cerebral Angiography / Q000379:methods*; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D020521:Stroke / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*