Improved two-dimensional J-resolved spectroscopy.
Localised two-dimensional J-resolved spectroscopy (JPRESS) is optimised for the in vivo detection of J-coupled metabolites using magnetic resonance spectroscopy at 3 T. The acquisition of echo signals starts as early as possible (i.e. maximum-echo sampling). This sampling scheme increases sensitivity and decreases overlap of peak tails, hence alleviating baseline problems. Reconstruction issues are discussed and the sensitivity is compared analytically with that of 1D PRESS. The qualitative behaviour of eddy currents in JPRESS is outlined and a 2D eddy current correction procedure based on the 1D phase deconvolution method is proposed.
Schulte
Rolf F
RF
Institute for Biomedical Engineering, University and ETH Zurich, CH-8092 Zurich, Switzerland.
Lange
Thomas
T
Beck
Johannes
J
Meier
Dieter
D
Boesiger
Peter
P
D000328:Adult; D000465:Algorithms; D002794:Choline / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000378:metabolism*; D010296:Parietal Lobe / Q000378:metabolism*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013057:Spectrum Analysis / Q000379:methods; D014018:Tissue Distribution
D009419:Nerve Tissue Proteins; D018377:Neurotransmitter Agents; D002794:Choline