Achyranthes aspera stimulates the immunity and enhances the antigen clearance in Catla catla.
Achyranthes aspera, an Indian medicinal plant (family: Amaranthaceae) was incorporated in artificial fish diet, and fed to catla Catla catla. After 4 weeks of feeding, fish were immunized with bovine serum albumin (BSA), spleen and blood were sampled on weekly intervals for four times after immunization. Antigen-specific antibody level in serum was determined by ELISA. Antigen clearance was determined in spleen by immuno-electron microscopy. Achyranthes has significantly (P<0.05) enhanced the BSA-specific antibody titers than the untreated control group throughout the study period. The efficiency of antigen clearance was also enhanced in C. catla treated with Achyranthes.
Chakrabarti
Rina
R
Department of Zoology, University of Delhi, Delhi--110 007, India. rina@ndf.vsnl.net.in
Vasudeva
Rao Y
RY
D029044:Achyranthes / Q000737:chemistry*; D000818:Animals; D000941:Antigens / Q000276:immunology; D002347:Carps; D002417:Cattle; D007114:Immunization; D008854:Microscopy, Electron; D010936:Plant Extracts / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000276:immunology*; D013154:Spleen / Q000187:drug effects* / Q000276:immunology / Q000648:ultrastructure
D000941:Antigens; D010936:Plant Extracts; D012710:Serum Albumin, Bovine