Adamantinoma of tibia: a study of 12 cases.
BACKGROUND
Adamantinoma is a rare tumor of long bones that can be mistaken for a carcinoma, and numerous other lesions such as myoepithelial tumor, malignant mixed tumor of bone, fibrous dysplasia/osteofibrous dysplasia, and vascular tumors.


METHODS
The histology and clinical features of 12 cases accrued from the surgical pathology files over a period of 23 years were analyzed.


RESULTS
Of the 12 cases, 4 were men and 8 women, with a mean age of 30 years. Radiologically the tumor presented as a lytic, eccentric, intracortical lesion in the tibia. The histology revealed epithelial islands with basaloid, spindle, and squamous features on a background of fibrotic stroma. Three patients came back with local recurrences, and one of them developed pulmonary metastasis.


CONCLUSIONS
In this article, an attempt is made to study the morphology, biology, and the differential diagnoses of adamantinoma of long bones.
Department of Pathology, Tata Memorial Hospital, Dr. Ernest Borges Road, Parel, Mumbai, India. saraldesai@hotmail.com
Saral S
SS
Desai
Nirmala
N
Jambhekar
Manish
M
Agarwal
Ajay
A
Puri
Nikhil
N
Merchant
D050398:Adamantinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis; D005360:Fibula / Q000473:pathology; D006801:Humans; D008297:Male; D011859:Radiography; D013977:Tibia / Q000473:pathology; D016896:Treatment Outcome