Isolated bone marrow occurrence of classic Hodgkin's lymphoma in an HIV-negative patient.
Classic Hodgkin's Lymphoma is a disease usually characterized by lymph nodal presentation. Rare cases with extra-nodal first clinical manifestation may occur, and primary bone marrow involvement may be part of them: isolated bone marrow forms have been recently described in the context of HIV infection. We herein report a case of isolated bone marrow Hodgkin's Lymphoma occurrence in a HIV-negative, elderly patient. The impacts of such unusual Hodgkin's Lymphoma manifestation on clinical practice as well as the related diagnostic and therapeutic implications are discussed.
Pathology Unit, Department of Oncology, San Raffaele H Scientific Institute, Milan, Italy. ponzoni.maurilio@hsr.it
Maurilio
M
Ponzoni
Fabio
F
Ciceri
Roberto
R
Crocchiolo
Graziana
G
Famoso
Claudio
C
Doglioni
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D015658:HIV Infections / Q000175:diagnosis; D015497:HIV-1; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans