[Correlation between the lung pixel indexes of multi-slice spiral CT and pulmonary function test].
OBJECTIVE
To study the correlation between the lung pixel indexes of multi-slice spiral CT (MSCT) and pulmonary function test (PFT), and to explore the CT features of histograms of lung attenuation.


METHODS
MSCT scan and pulmonary function test (PFT) were separately performed in 127 subjects within one week. The total lung was scanned with MSCT at full inspiration, full expiration, and normal respiration. The lung pixel indexes were measured by Pulmo pulmonary quantitative software. These indexes include PI(-910Huin), PI(-960HUEX), PI(-910Huin), PI(-960Huex), PI(-910(Hun), PI(-960Hun), PI(910Huex/in), and the histograms of lung attenuation.


RESULTS
Correlation existed between all the lung pixel indexes of MSCT and PFT. PI(-910Huex/in showed the best correlation with FEV1/FVC (r = 0.901, P < 0.01). Three distribution patterns were found in the histograms of lung attenuation of total lung, including double-peak distribution (n = 28), similar normal distribution (n = 81), and partial distribution (n = 18).


CONCLUSIONS
The lung pixel indexes of MSCT have significant correlation with PFT and can be used to assess the pulmonary function.
Department of Radiology, Shanghai Huadong Hospital, Shanghai 200040, China. bz4dhx@sohu.com
Xiao-jun
XJ
Ge
Guo-zhen
GZ
Zhang
Ding-biao
DB
Mao
Qi-yong
QY
Ding
Yan-qing
YQ
Hua
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests; D036542:Tomography, Spiral Computed