Autolytic properties of glycopeptide-intermediate Staphylococcus aureus Mu50.
Whole-cell autolytic activity of prototypical glycopeptide-intermediate Staphylococcus aureus (GISA) Mu50 was reduced versus that of hetero-GISA Mu3 and glycopeptide-susceptible S. aureus, consistent with other GISA strains. In contrast, autolytic activity was relatively high in Mu50 crude cell walls and autolysin extracts against purified cell walls, reflecting the complexities of autolytic activity regulation.
Microbiology Group, Department of Biological Sciences, 210 Julian Hall, Illinois State University, Normal, Illinois 61790-4120, USA.
Sugunya
S
Utaida
Richard F
RF
Pfeltz
R K
RK
Jayaswal
B J
BJ
Wilkinson
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001433:Bacteriolysis / Q000187:drug effects*; D006020:Glycopeptides / Q000378:metabolism / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000378:metabolism; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D006020:Glycopeptides; D014640:Vancomycin