Clinical pharmacokinetics of voriconazole.
This review presents the published clinical pharmacokinetic data for the antifungal agent voriconazole. Aspects regarding absorption, tissue distribution, elimination and kinetic interactions are also discussed.
Department of Pharmacy, Hôpital Hautepierre, Avenue Molière, 67000 Strasbourg, France. dominique.leveque@chru-strasbourg.fr
Dominique
D
Levêque
Yasmine
Y
Nivoix
François
F
Jehl
Raoul
R
Herbrecht
D000042:Absorption; D000935:Antifungal Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D008657:Metabolic Clearance Rate; D011743:Pyrimidines / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D014018:Tissue Distribution; D014230:Triazoles / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole