Treatment of local recurrences of giant cell tumour in long bones after curettage and cementing. A Scandinavian Sarcoma Group study.
We retrospectively studied local recurrence of giant cell tumour in long bones following treatment with curettage and cementing in 137 patients. The median follow-up time was 60 months (3 to 166). A total of 19 patients (14%) had at least one local recurrence, the first was diagnosed at a median of 17 months (3 to 29) after treatment of the primary tumour. There were 13 patients with a total of 15 local recurrences who were successfully treated by further curettage and cementing. Two patients with a second local recurrence were consequently treated twice. At the last follow-up, at a median of 53 months (3 to 128) after the most recent operation, all patients were free from disease and had good function. We concluded that local recurrence of giant cell tumour after curettage and cementing in long bones can generally be successfully treated with further curettage and cementing, with only a minor risk of increased morbidity. This suggests that more extensive surgery for the primary tumour in an attempt to obtain wide margins is not the method of choice, since it leaves the patient with higher morbidity with no significant gain with respect to cure of the disease.
Vult von Steyern
F
F
Department of Orthopaedics, Lund University Hospital, SE-221 85 Lund, Sweden. Fredrik.VultvonSteyern@skane.se
Bauer
H C F
HC
Trovik
C
C
Kivioja
A
A
Bergh
P
P
Holmberg Jörgensen
P
P
Follerås
G
G
Rydholm
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000601:surgery*; D002484:Cementation / Q000379:methods; D003475:Curettage / Q000379:methods; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery; D005269:Femur / Q000601:surgery; D018212:Giant Cell Tumor of Bone / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D019637:Orthopedic Procedures / Q000379:methods; D011884:Radius / Q000601:surgery; D012086:Reoperation / Q000379:methods; D012189:Retrospective Studies; D013977:Tibia / Q000601:surgery; D017211:Treatment Failure; D016896:Treatment Outcome