Pathogenesis of columnar-lined esophagus.
Since its initial description, the pathogenesis of the columnar-lined esophagus (CLE) has been surrounded by many controversies. The first controversy is related to the existence of the condition itself. The second controversy centers on whether the CLE is a congenital or an acquired condition. In this article, we review the congenital and acquired theories of development of CLE and discuss the various factors in acquisition of CLE. The bulk of evidence in the literature suggests that CLE is an acquired condition.
Department of Surgery, Faculty of Medicine, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan. banihani60@yahoo.com
Kamal E
KE
Bani-Hani
Bayan K
BK
Bani-Hani
D000230:Adenocarcinoma / Q000209:etiology / Q000473:pathology; D001471:Barrett Esophagus / Q000209:etiology* / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D004938:Esophageal Neoplasms / Q000209:etiology / Q000473:pathology; D004947:Esophagus / Q000473:pathology*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000473:pathology; D006801:Humans; D009092:Mucous Membrane / Q000473:pathology; D011230:Precancerous Conditions / Q000473:pathology