Biodosimetry study in Dolon and Chekoman villages in the vicinity of Semipalatinsk nuclear test site.
In this paper, the results of a biodosimetry investigation are reported for two villages in the area of the Semipalatinsk nuclear testing site: Chekoman and Dolon. Chekoman village is considered to be relatively less affected by radiation in comparison with Dolon village. The distance between the two villages is about 100 km and the life styles of the residents are similar. Chromosome aberrations in lymphocytes collected from the residents of the two villages were analyzed using the fluorescence in situ hybridization technique. Our results showed that the average frequency of stable translocations for the Dolon group was significantly greater that of the Chekoman group. The elevated level of stable translocations with the Dolon residents corresponds to a dose of about 180 mSv.
Scientific Research Institute for Radiation Medicine and Ecology, Semipalatinsk, Republic of Kazakhstan. nii_rm@semsk.kz
Nailya
N
Chaizhunusova
Tracy C
TC
Yang
Charles
C
Land
Nickolas
N
Luckyanov
Honglu
H
Wu
Kazbek N
KN
Apsalikov
Madina
M
Madieva
D000328:Adult; D001681:Biological Assay / Q000379:methods*; D001822:Body Burden; D002869:Chromosome Aberrations / Q000706:statistics & numerical data*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000706:statistics & numerical data*; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D008214:Lymphocytes / Q000528:radiation effects / Q000648:ultrastructure*; D009689:Nuclear Warfare / Q000706:statistics & numerical data*; D011832:Radiation Injuries / Q000453:epidemiology* / Q000235:genetics; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors