Fulminant liver failure secondary to mushroom poisoning in children: importance of early referral to a liver transplantation unit.
Patients poisoned with toxic mushrooms have a spectrum of clinical presentations ranging from gastrointestinal symptoms to fulminant liver failure, and outcomes range from complete recovery to the need for liver transplantation. We reviewed the clinical presentation, course, outcome and management of four children poisoned with mushrooms who developed fulminant liver failure. Although one patient survived, two children died and one underwent living related liver transplantation. Early referral to specialized centers for treatment and for liver transplantation is emphasized.
Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Başkent University Medical Faculty, Ankara, Turkey. fozcay@yahoo.com
Figen
F
Ozçay
Esra
E
Baskin
Nurhan
N
Ozdemir
Hamdi
H
Karakayali
Remzi
R
Emiroglu
Mehmet
M
Haberal
D002648:Child; D002675:Child, Preschool; D005260:Female; D006501:Hepatic Encephalopathy / Q000209:etiology; D006801:Humans; D008658:Inactivation, Metabolic; D008099:Liver / Q000473:pathology; D017114:Liver Failure, Acute / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D009145:Mushroom Poisoning / Q000097:blood / Q000150:complications / Q000473:pathology / Q000628:therapy*; D010956:Plasmapheresis; D011379:Prognosis; D012017:Referral and Consultation