[The role of first pass and delayed contrast-enhancement magnetic resonance imaging in patients with myocardial infarction].
OBJECTIVE
To evaluate the role of contrast-enhancement magnetic resonance imaging (CeMRI) in patients with myocardial infarction (MI).


METHODS
There were twenty-three patients enrolled in this study. After dynamic observation, there were 20 patients who were diagnosed as MI. All those patients underwent coronary artery angiography and CeMRI. MRI was performed with a 1.5-T magnet (AVANTO, SIMENS). After tagged images were acquired, the patients received an intravenous bolus of 0.1 mmol/kg Gd-DTPA at a rate of 5 ml/s. A first-pass perfusion scan was acquired simultaneously with a bolus injection. A second bolus of 0.3 mmol/kg Gd-DTPA was given following the first-pass images. Delayed images were acquired 5 minutes after the second bolus by using an inversion-recovery prepared gated fast-gradient echo-pulse sequence.


RESULTS
Hypoenhancement was seen in 20 patients at the first-pass perfusion at the myocardial infarction site, while hyperenhancement was seen at delayed CeMRI. Myocardial infarction area in delayed CeMRI was 16.58% +/- 9.73%, which was correlated positively with peak CK and cTnT (r = 0.821, P < 0.01 and r = 0.565, P < 0.05), respectively. The ejection fraction (EF) detected by MRI was 0.46 +/- 0.13, while the left ventricular EF (LVEF) detected by left ventriculography was 0.49 +/- 0.16. There was no difference between two parameters.


CONCLUSIONS
CeMRI may play an important role in the diagnosis and prognosis of patients with MI.
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Medicine, 200032, China.
Jian-ying
JY
Ma
Ju-ying
JY
Qian
Jun-bo
JB
Ge
Shan
S
Yang
Lei
L
Ge
Xue-bo
XB
Liu
Jin-yi
JY
Lin
Xin-ying
XY
Hu
Feng
F
Zhang
Shao-heng
SH
Zhang
Rong-chong
RC
Huang
Yan-lin
YL
Li
Hong-yu
HY
Shi
Bing
B
Fan
D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*
D003287:Contrast Media; D019786:Gadolinium DTPA