Adsorption and spontaneous rupture of vesicles composed of two types of lipids.
To analyze the adsorption of single vesicles composed of two types of lipids (e.g., zwitterionic and positively charged lipids or zwitterionic and negatively charged lipids), we propose a statistical model taking into account lipid-surface interactions, lipid-lipid lateral interactions, and vesicle bending energy. Our treatment specifies how these parameters govern vesicle adsorption, shows how the radius of the vesicle-surface contact area may depend on the vesicle composition, and clarifies the conditions for vesicle rupture.
Zhdanov
Vladimir P
VP
Department of Applied Physics, Chalmers University of Technology, S-412 96 Göteborg, Sweden. zhdanov@catalysis.nsk.su
Dimitrievski
Kristian
K
Kasemo
Bengt
B
D000327:Adsorption; D002118:Calcium / Q000737:chemistry / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry; D008055:Lipids / Q000737:chemistry*; D008560:Membrane Fluidity; D008561:Membrane Fusion; D015233:Models, Statistical; D010713:Phosphatidylcholines / Q000737:chemistry; D013499:Surface Properties
D008051:Lipid Bilayers; D008055:Lipids; D010713:Phosphatidylcholines; D002118:Calcium