Daphmanidins E and F, alkaloids from Daphniphyllum teijsmannii.
Two new Daphniphyllum alkaloids, daphmanidins E (1) and F (2), have been isolated from the leaves of Daphniphyllum teijsmannii, and the structures were elucidated on the basis of spectroscopic data. Daphmanidins E and F showed a moderate vasorelaxant effect on rat aorta.
Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan. moritah@hoshi.ac.jp
Hiroshi
H
Morita
Nozomi
N
Ishioka
Hiroshi
H
Takatsu
Toru
T
Iizuka
Jun'ichi
J
Kobayashi
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D001011:Aorta / Q000187:drug effects; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D014665:Vasodilator Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000470:Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; D014665:Vasodilator Agents; C510043:daphmanidin E; C510044:daphmanidin F