Acetaminophen poisoning.
Acetaminophen (acetyl-para-amino-phenol or APAP), an antipyretic and analgesic, is a common component in hundreds of over-the-counter and prescription medications. The wide usage of this drug results in many potentially toxic exposures. It is therefore critical for the clinician to be comfortable with the diagnosis and treatment of APAP toxicity. Prompt recognition of APAP overdose and institution of appropriate therapy are essential to preventing morbidity and mortality.
Rowden
Adam K
AK
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia, Charlottesville, VA 22908, USA. ar6r@virginia.edu
Norvell
Jeffrey
J
Eldridge
David L
DL
Kirk
Mark A
MA
D000082:Acetaminophen / Q000506:poisoning*; D000111:Acetylcysteine / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D000931:Antidotes / Q000627:therapeutic use; D006801:Humans; D011041:Poisoning / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
D018712:Analgesics, Non-Narcotic; D000931:Antidotes; D000082:Acetaminophen; D000111:Acetylcysteine