[About the "double" radioprotecting mechanism of some sulfur-containing substances].
The hypothesis about the double-acting mechanism of some radioprotectors during the irradiation of the DNA solutions is expressed in literature: the water radicals interception and the formation up to the irradiation of the additional intermolecular bonds "protector-DNA" (stabilization of the double helix). The realization conditions of this hypothesis were obtained by the molecular mechanics methods and the free radical mechanism appearance of the intrastrand cross-links "protector-DNA" during the irradiation of the polymer is given.
P A
PA
Kuzurman
V A
VA
Sharpatyĭ
D004247:DNA / Q000187:drug effects* / Q000528:radiation effects*; D005720:Gamma Rays; D006801:Humans; D011837:Radiation-Protective Agents / Q000737:chemistry / Q000494:pharmacology*; D013457:Sulfur Compounds / Q000737:chemistry / Q000494:pharmacology*
D011837:Radiation-Protective Agents; D013457:Sulfur Compounds; D004247:DNA