Jumbo biopsy is useful for the diagnosis of colonic prolapsing mucosal polyps with diverticulosis.
We report here a case of multiple prolapsing mucosal polyps with diverticulosis in the sigmoid colon. A 52-year-old man was admitted to our hospital because of bloody diarrhea. Colonoscopy and barium enema showed multiple diverticula, markedly thickened mucosal folds and polypoid lesions with mucus on the top of them in the sigmoid colon. Endoscopic ultrasonography showed thickening of the mucosal and submucosal layers. Several endoscopic biopsy specimens were taken from the polypoid lesions. Histological examination revealed only chronic inflammatory cell infiltration. In order to obtain a definite diagnosis, we performed endoscopic jumbo biopsy for the polypoid lesions after obtaining informed consent. Histological examination revealed marked lymphocyte infiltration, hemosiderin deposits and fibromuscular obliteration in the lamina propria, features similar to those of mucosal prolapsing syndrome. After anti-diarrhetic treatment, clinical findings were improved. Thus, jumbo biopsy is useful for diagnosis and treatment of prolapsing mucosal polyps.
Fukuoka Japan Self Defense Forces Hospital, Second Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa City, Saitama 359-8513, Japan. sycm-katos@jcom.home.ne.jp
Shingo
S
Kato
Kazutoshi
K
Hashiguchi
Ryuichi
R
Yamamoto
Mitsuru
M
Seo
Takashi
T
Matsuura
Kazuro
K
Itoh
Akinori
A
Iwashita
Soichiro
S
Miura
D001706:Biopsy / Q000379:methods; D003106:Colon / Q000000981:diagnostic imaging / Q000473:pathology; D003111:Colonic Polyps / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D004239:Diverticulitis, Colonic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D019160:Endosonography; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012005:Rectal Prolapse / Q000150:complications / Q000175:diagnosis* / Q000473:pathology