[Elastic modulus of small intestinal submucosa].
OBJECTIVE
to determine the modulus of elasticity (E) of small intestinal submucosa (SIS), a new biological graft material.


METHODS
The longitudinal tensile testing was performed on 21 specimens of canine jejunum with the electronic material test machine.


RESULTS
Stress (sigma)-strain (epsilon) data were obtained. It was found that the stress (sigma)-strain (epsilon) data fitted the expression sigma = Kiepsilon(alpha) very well, the mean correlation coefficients R2 was 0. 991 6. Then the expression of the modulus of elasticity (E) of SIS was E=K(1/alpha)sigma(1-1/alpha). The mean values of alpha and K were 3.966 9 and 374.55, so E = 4.3992sigma(0.75).


CONCLUSIONS
The modulus of elasticity was found to increase with increasing stress. The variations law is similar to that of the vessels. Furthermore when sigma is 0.01333 MPa (100 mmHg), E is about 0.16 MPa, which is similar to that of the vessels.
School of Life Science and Technology, Tongji University, Shanghai 200092, P R China. lengye@mail.tongji.edu.cn
Ye
Y
Leng
Zuquan
Z
Ding
Lulu
L
Gong
D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D055119:Elastic Modulus; D007413:Intestinal Mucosa; D007421:Intestine, Small; D015607:Stents; D023822:Tissue Engineering
D001672:Biocompatible Materials