Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve.
Koçer
Armagan
A
BiOMaDe Technology Foundation, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Walko
Martin
M
Bulten
Erna
E
Halza
Erik
E
Feringa
Ben L
BL
Meijberg
Wim
W
D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism; D015374:Biosensing Techniques / Q000379:methods*; D016503:Drug Delivery Systems; D005452:Fluoresceins / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000737:chemistry / Q000378:metabolism; D011522:Protons
D001426:Bacterial Proteins; D005452:Fluoresceins; D005456:Fluorescent Dyes; D008565:Membrane Proteins; D010713:Phosphatidylcholines; D011522:Protons; C017251:1,2-oleoylphosphatidylcholine; C007740:fluorexon