Gene expression profiling as novel tool in experimental asthma research.
With the advances achieved in decoding of the genetic structures of species and the novel possibilities of simultaneous measurements of the regulation of all genes of a given tissue, the last 10 years have seen a massive increase of our knowledge about genetic regulation of diseases. Additionally, the possibilities to control transcriptional processes within the cells will speed up the process of disentangling the various pathways leading to disease.
Department of Pediatric Pneumonology and Immunology, Charité Universitätsmedizin, Augustenburger Platz 1, 13353 Berlin, Germany.
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Dittrich
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Quarcoo
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Krokowski
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Ahrens
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Hamelmann
D000818:Animals; D001249:Asthma / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D016535:Bronchial Hyperreactivity / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D004195:Disease Models, Animal; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D020022:Genetic Predisposition to Disease; D006801:Humans; D051379:Mice; D014158:Transcription, Genetic