Physiologic versus anatomic repair of congenitally corrected transposition of the great arteries: meta-analysis of individual patient data.
The objective of this meta-analysis of individual patients' data was to compare the immediate outcomes of anatomic and physiologic repair of congenitally corrected transposition of the great arteries. Eleven nonrandomized studies, involving 124 patients, met the inclusion criteria for this review. The Rastelli type anatomic repair and the era of surgery were significantly related to the outcome in different tested models. Entering all variables into the logistic regression model showed a significant protective effect of the Rastelli type anatomic repair (odds ratio = 0.05, 95% confidence interval: 0.01, 0.50, p = 0.02).
Division of Cardiac Surgery, Congenital Cardiac Surgery Program, Department of Surgery, University of Toronto, Toronto, Ontario, Canada. abdullah.alghamdi@utoronto.ca
Abdullah A
AA
Alghamdi
Brian W
BW
McCrindle
Glen S
GS
Van Arsdell
D000293:Adolescent; D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D002675:Child, Preschool; D006330:Heart Defects, Congenital / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000601:surgery; D006801:Humans; D007223:Infant; D008875:Middle Aged; D014188:Transposition of Great Vessels; D016896:Treatment Outcome