Complete pancreatic heterotopia of gallbladder with hypertrophic duct simulating an adenomyoma.
The gallbladder is an unusual location of pancreatic heterotopia, defined as the presence of pancreatic tissue lacking anatomical and vascular continuity with the main body of the gland. A 28-year-old man presented with anorexia, nausea and pain in the right upper abdomen. On physical examination, the abdomen was tender to palpation and Murphy sign was positive. The patient underwent a cholecystecomy. This case, in our opinion, is very interesting since it permits to consider a controversial issue in the pathology of the gallbladder. The histological appearance of ductal structure in pancreatic heterotopia resembles the histological picture of both Aschoff-Rokitansky (AR) sinuses and adenomyomas. This finding suggests that these lesions are linked by a common histogenetic origin. We suggest that the finding of an adenomyoma in the gallbladder should prompt an extensive sampling of the organ in order to verify the coexistence of pancreatic rests.
Pilloni
Luca
L
Istituto di Anatomia Patologica, Dipartimento di Citomorfologia, Universitá degli Studi di Cagliari, Via Ospedale 46, Cagliari 09124, Italy. lucpilloni@tiscali.it
Cois
Alessandro
A
Uccheddu
Alessandro
A
Ambu
Rossano
R
Coni
Pierpaolo
P
Faa
Gavino
G
D018194:Adenomyoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002763:Cholecystectomy; D002828:Choristoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005705:Gallbladder Diseases / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D010179:Pancreas; D010183:Pancreatic Ducts / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery