Intracranial non-Hodgkin's MALT lymphoma mimicking a large convexity meningioma.
Primary presentation of an intradural Non-Hodgkin's lymphoma is rare. Recently these B cell lymphomas of mucosa associated lymphoid tissue (MALT) have gained acceptance as an important pathological subtype and are distinguishable from other primary CNS lymphomas that exhibit aggressive behaviour. Over the past decade a number of these lesions have been reported to resemble a meningioma both intra-operatively and radiologically. The authors outline such a case of marginal zone B cell lymphoma that clinically and radiologically resembled a meningioma. This case illustrates the rare occurrence of low grade dural B cell lymphoma and the need to consider this entity in the differential diagnosis of CNS lesions, if appropriate targeted therapy is to be administered.
Department of Neurosurgery, Leeds General Infirmary, Leeds, UK. gpavs@yahoo.com
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G
Pavlou
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Pal
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Bucur
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A
Chakrabarty
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PT
van Hille
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D008579:Meningioma / Q000175:diagnosis; D019635:Neurosurgical Procedures; D010386:Pelvic Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D014408:Biomarkers, Tumor