Antioxidant activity of diterpenes and polyphenols from Ophryosporus heptanthus.
The antioxidant activity of 14 compounds (1-14) isolated from the ether and butanolic extracts of the aerial parts of Ophryosporus heptanthus has been assayed using a beta-carotene bleaching method and the DPPH technique. Compounds 1 and 13 showed the most potent antioxidant activity. Their structures have been established by spectroscopic techniques (mainly NMR). Compounds 7 and 12 are new natural products, and their structures have been confirmed by chemical synthesis.
Departamento de Química Organica, Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva, s/n, 18071 Granada, España. afbarre@ugr.es
Alejandro F
AF
Barrero
M Mar
MM
Herrador
Pilar
P
Arteaga
Alfredo
A
Rosas-Romero
Jesús F
JF
Arteaga
D000975:Antioxidants / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D059808:Polyphenols
D000975:Antioxidants; D004224:Diterpenes; D005419:Flavonoids; D010636:Phenols; D059808:Polyphenols