[Individualization of immunosuppressive treatment in patients with HCV infection after transplantation].
The number of patients with HCV infection is increasing in Georgia. High number of infection is noticeable in patients on hemodialysis. 60-70% of them needs renal transplantation. This makes the problem more acute especially among the organ recipients with HCV infection, who are receiving immunosuppressive treatment. The aim of the survey was to work out optimal protocol of immunosuppressive treatment for patients after renal transplantation. There were clinically observed 39 patients after renal transplantation. They were divided into four groups according to the clinical data (serology, replication of HCV and different schemes of immunosuppressive treatment). It was shown that immunosuppressive treatment carried out among patients with HCV infection after transplantation is effective and safe. Consideration of the data leads us to the statement that there is no risk of losing transplanted organ in case of individualization and minimization of immunosuppressive treatment. Periodic control of blood HCV RNA is reasonable during the pre and post operation period.
Gongadze
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Tsuladze
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SIa
Gongadze
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EI
D000328:Adult; D005260:Female; D005921:Glomerulonephritis / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology* / Q000601:surgery*; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D016030:Kidney Transplantation; D008297:Male; D014850:Waiting Lists