Episodic nocturnal wandering in a patient with epilepsy due to a right temporoinsular low-grade glioma: relief following resection. Case report.
Although controversial, episodic nocturnal wandering (ENW) is thought to be a rare and atypical form of nocturnal epilepsy, originating in the frontal lobe and responsive to antiepileptic drugs (AEDs). The authors report the case of a patient harboring a right temporoinsular low-grade glioma, who presented with a 3-year history of agitated somnambulent episodes resistant to AEDs. Interestingly, the ENW totally resolved after tumor resection and the patient reported no recurrence during a follow-up period of 4.5 years. To the authors' knowledge, this is the first report of ENW due to a glioma; the findings support the theory that ENW may represent an unusual type of lesional epilepsy that is surgically correctable. Moreover, a temporoinsular origin of ENW can now be considered.
Department of Neurosurgery, Hopital Salpetriere, Paris, France. hugues.duffau@psl.ap-hop-paris.fr
Hugues
H
Duffau
Michèle
M
Kujas
Luc
L
Taillandier
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000601:surgery*; D004827:Epilepsy / Q000150:complications* / Q000209:etiology*; D005910:Glioma / Q000150:complications* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013009:Somnambulism / Q000209:etiology*; D013702:Temporal Lobe / Q000473:pathology; D016896:Treatment Outcome