Anatomy of the hypophysiotropic somatostatinergic and growth hormone-releasing hormone system minireview.
The central control of growth hormone (GH) secretion from the pituitary gland is ultimately achieved by the interaction between two hypothalamic neurohormones, somatostatin which inhibits and growth hormone-releasing hormone (GHRH) which stimulates GH release. The regulation of the somatostatin and GHRH release from the hypothalamus is regulated by a range of other neuropeptides, neurotransmitters, neurohormones. In this mini review we attempt to provide a short summary covering the anatomy and chemical characteristics of the various cell populations regulating GH secretion as a tribute to Miklós Palkovits who pioneered the field of functional neuroanatomy of hypothalamic networks.
Department of Pediatrics, VU University Medical Center, Amsterdam, The Netherlands. M.Fodor@lumc.nl
Mariann
M
Fodor
Claude
C
Kordon
Jacques
J
Epelbaum
D000818:Animals; D013007:Growth Hormone-Releasing Hormone / Q000502:physiology*; D010902:Pituitary Gland / Q000033:anatomy & histology*; D010907:Pituitary Hormones / Q000502:physiology*; D011863:Radioimmunoassay; D013004:Somatostatin / Q000502:physiology*
D010907:Pituitary Hormones; D013004:Somatostatin; D013007:Growth Hormone-Releasing Hormone