Budd-Chiari syndrome in a child due to a membranous web of the inferior vena cava resolved by systemic and local recombinant tissue plasminogen activator treatment.
Budd-Chiari syndrome is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction. Although there are no guidelines for treatment of patients with Budd-Chiari syndrome, thrombolytic therapy may be useful in patients with acute Budd-Chiari syndrome. In this report, a boy with Budd-Chiari syndrome due to membranous obstruction of the inferior vena cava treated with systemic and local administration of recombinant tissue plasminogen activator is described. We would like to emphasize the role of systemic and local fibrinolytic treatment in these patients.
Department of Pediatric Hematology, Baskent University Faculty of Medicine, Ankara, Turkey. alioglub@gmail.com
Bülent
B
Alioğlu
Zekai
Z
Avci
Cüneyt
C
Aytekin
Sükrü
S
Mercan
Figen
F
Ozçay
Emin
E
Kürekçi
Namk
N
Ozbek
D000293:Adolescent; D000792:Angiography; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D011994:Recombinant Proteins / Q000008:administration & dosage; D012016:Reference Values; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000002:abnormalities* / Q000000981:diagnostic imaging
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator