Initial European clinical experience with pulsatile extracorporeal membrane oxygenation.
BACKGROUND
Extracorporeal membrane oxygenation (ECMO) for post-cardiotomy heart failure in neonates and infants still carries high mortality and morbidity rates. In this study we present the first European clinical experience with the Medos DeltaStream DP1, a new pulsatile flow pump, in neonates and infants.


METHODS
The DP1 is an extracorporeal rotary blood pump. The pump features a diagonal flow impeller, and can be used for both continuous and pulsatile output. Special characteristics include its small priming volume of approximately 30 ml and a high pumping capacity. A temperature sensor and speed sensors are integrated into the pump. The pump has a delivery rate of up to 8 liters/min and a speed range of 100 to 10,000 rpm.


RESULTS
Two patients being assisted with the pulsatile pump system were successfully weaned after 36 and 53 hours, respectively.


CONCLUSIONS
Based on our limited experience with 2 patients, we believe that pulsatile DP1 device is a reasonable alternative to current conventional non-pulsatile systems.
Agati
Salvatore
S
Pediatric Cardiac Surgery Unit, San Vincenzo Hospital, Taormina, Italy. sasha.agati@tiscali.it
Mignosa
Carmelo
C
Ciccarello
Giuseppe
G
Salvo
Dario
D
Undar
Akif
A
D006348:Cardiac Surgical Procedures; D005060:Europe; D015199:Extracorporeal Membrane Oxygenation / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery; D006333:Heart Failure / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000151:congenital / Q000601:surgery; D011183:Postoperative Complications; D011673:Pulsatile Flow / Q000502:physiology*; D012086:Reoperation; D018487:Ventricular Dysfunction, Left / Q000209:etiology