Cyclic semipeptoids: peptoid-organic hybrid macrocycles.
[structure: see text] Cyclic semipeptoids 1 and 2 represent constrained, secondary structure mimics where the R(1) and R(2) side chains correspond to those of amino acids. Solid-phase syntheses and conformational analyses of these compounds are described.
Texas A&M University, Chemistry Department, P.O. Box 30012, College Station, Texas 77842, USA.
Ernest
E
Nnanabu
Kevin
K
Burgess
D000596:Amino Acids / Q000737:chemistry*; D008958:Models, Molecular; D018716:Molecular Mimicry; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry*; D034444:Peptoids / Q000138:chemical synthesis* / Q000737:chemistry*; D011487:Protein Conformation
D000596:Amino Acids; D010456:Peptides, Cyclic; D034444:Peptoids