Synthesis, stability and optimized photolytic cleavage of 4-methoxy-2-nitrobenzyl backbone-protected peptides.
We demonstrate the potential of 4-methoxy-2-nitrobenzyl as a Boc chemistry-compatible fully reversible backbone modification for synthetic peptides.
Institute for Biophysical Dynamics, Department of Biochemistry and Molecular Biology,The University of Chicago, 920 East 58th Street, Chicago, IL 60637, USA.
Erik C B
EC
Johnson
Stephen B H
SB
Kent
D005563:Formic Acid Esters / Q000737:chemistry* / Q000528:radiation effects; D009578:Nitrobenzenes / Q000737:chemistry; D010455:Peptides / Q000138:chemical synthesis*; D010782:Photolysis; D014466:Ultraviolet Rays
D005563:Formic Acid Esters; D009578:Nitrobenzenes; D010455:Peptides; C000345:t-butyloxycarbonyl group; C036077:nitrobenzene