[Comparison of prophylactic infusion of ephedrine and phenylephrine during Cesarean section under spinal anaesthesia].
Spinal anaesthesia for caesarean delivery may be associated with hypotension and fetal acidosis. Prophylactic infusion of phenylephrine (PE) immediately after the induction of anaesthesia appears to be a more effective approach than administration of ephedrine to reduce the incidence, frequency and severity of hypotension. Furthermore, PE appears to be associated with better fetal acid-base status than is ephedrine.
H:S Rigshospitalet, Juliane Marie Center, Anaestesiologisk Afsnit, København Ø. arriba_a@yahoo.dk
Arash
A
Afshari
Ann M
AM
Møller
Niels
N
Hangaard
D000138:Acidosis / Q000517:prevention & control; D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage* / Q000009:adverse effects; D000773:Anesthesia, Obstetrical / Q000009:adverse effects; D000775:Anesthesia, Spinal / Q000009:adverse effects; D002585:Cesarean Section; D004809:Ephedrine / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007022:Hypotension / Q000517:prevention & control; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D010656:Phenylephrine / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy; D014662:Vasoconstrictor Agents / Q000008:administration & dosage* / Q000009:adverse effects
D000316:Adrenergic alpha-Agonists; D014662:Vasoconstrictor Agents; D010656:Phenylephrine; D004809:Ephedrine