Neonatal nosocomial infections in Bahrami Children Hospital.
OBJECTIVE
Nosocomial infections are one of the most important causes of mortality and morbidity in hospitals. These are major public health problems worldwide, but particularly in developing countries. These infections have the most common frequency in pediatric hospitals-especially in neonatal wards- second to burn hospitals. In the present study, neonatal nosocomial infections have been reviewed in Bahrami Children Hospital from fall of 1999 through fall of 2004.


METHODS
Nosocomial infected patients were defined as all patients who were neither infected not were in incubation period at the admission time and had positive culture after third day of admission. The incidence of nosocomial infections computed as infections per 100 hospital discharges and infections per 100 hospital days. Chi square test was used for comparison of rates.


RESULTS
Fifty-two patients had been diagnosed having nosocomial infections. NICU (Neonatal Intensive Care Unit) showed the highest portion of infections (40%) followed by neonatal surgery ward (35%) and neonates ward (25%). Frequencies of nosocomial infection by site were as follows: eyes (27%), septicemia, surgical wounds and location of drain or catheter (each one 21%), CSF (7%) and urinary (2%). The most common pathogenic organisms were Enterobacter (27%), aurues Staphilococcus (21%), Klebsiella (18%), E.coli (14%) and epidermis Staphilococcus (9%). Total number of hospitalized patients was 5990 and total number of hospitalized days was 39,095 in the five years. Infections per 100 hospital discharges and 100 hospital days by service were as follows, respectively: NICU (2.9, 0.26), neonatal surgery (1.7, 0.18) and neonates (0.3, 0.06). The differences were significantly meaningful (p value< 0.001).


CONCLUSIONS
These findings provide useful information for future surveillance in association with prevention programs. Subsequently, surveillance should be focused on high-risk patients in intensive care unit and/or who have undergone surgery and invasive procedures.
Salamati
Payman
P
Trauma and Surgery Research Center, Bahrami Children Hospital, Tehran University of Medical Sciences, Iran. psalamati@tums.ac.in
Rahbarimanesh
Ali Akbar
AA
Yunesian
Masood
M
Naseri
Mohsen
M
D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data*; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D007492:Iran; D013514:Surgical Procedures, Operative / Q000009:adverse effects