Large conjugative plasmids from clinical strains of Salmonella enterica serovar virchow contain a class 2 integron in addition to class 1 integrons and several non-integron-associated drug resistance determinants.
Two large conjugative resistance (R) plasmids from clinical strains of Salmonella enterica serovar Virchow carried a class 2 integron with the 5' conserved sequence (5'CS)-dfrA1-sat1-aadA1-3'CS gene array, which is associated with defective Tn7 transposons. In addition, each contained a different class 1 integron (with 5'CS-aadA1-3'CS or 5'CS-sat-smr-aadA1-3'CS gene arrays) linked to Tn21-Tn9 sequences, and several non-integron-associated R determinants. An intact copy of Tn7 (including the class 2 integron) was present in the chromosome of each strain.
Departamento de Biología Funcional-Microbiología, Universidad de Oviedo, Julián Clavería no. 6, 33006-Oviedo, Spain.
Irene
I
Rodríguez
M Rosario
MR
Rodicio
M Carmen
MC
Mendoza
M
M
Cruz Martín
D001483:Base Sequence; D003227:Conjugation, Genetic; D004251:DNA Transposable Elements; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006801:Humans; D032023:Integrons; D008969:Molecular Sequence Data; D010957:Plasmids; D019779:Salmonella enterica / Q000235:genetics*
D004251:DNA Transposable Elements