Host-pathogen systems biology.
Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host-pathogen systems on a multitude of levels of detail has come within reach.
Forst
Christian V
CV
Bioscience Division, Los Alamos National Laboratory, Mailstop M888, P.O. Box 1663, Los Alamos, NM 87545, USA. chris@lanl.gov
D000818:Animals; D018407:Bacterial Physiological Phenomena; D003198:Computer Simulation; D015195:Drug Design; D006801:Humans; D007107:Immune System; D007239:Infections / Q000276:immunology / Q000382:microbiology; D008954:Models, Biological; D015398:Signal Transduction; D049490:Systems Biology; D014777:Virus Diseases / Q000276:immunology / Q000821:virology; D018406:Virus Physiological Phenomena