Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: a case report.
A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasonography. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endoscopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The resected margin of the tumor was positive for malignant cells. Two courses to transcatheter arterial chemotherapy for liver metastasis were ineffective. Accordingly, the rectal tumor and metastatic lymph nodes were surgically resected. One month after the operation, she received liver transplantation (left lateral segment and caudate lobe) from her son. No recurrent lesion has been observed at two years after the liver transplantation. Liver transplantation should be considered as a treatment option even in advanced case of carcinoid metastasis to the liver. We also discuss the literature on liver transplantation for metastatic carcinoid tumor.
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511, Japan. htakagi@med.gunma-u.ac.jp
Yoshimi
Y
Nakajima
Hitoshi
H
Takagi
Naondo
N
Sohara
Ken
K
Sato
Satoru
S
Kakizaki
Kenichi
K
Nomoto
Hideki
H
Suzuki
Taketoshi
T
Suehiro
Tatsuo
T
Shimura
Takayuki
T
Asao
Hiroyuki
H
Kuwano
Masatomo
M
Mori
Ken
K
Nishikura
D000328:Adult; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000473:pathology*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D009034:Mother-Child Relations; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D014463:Ultrasonography