Identical twins with hypertrophic cardiomyopathy and apical aneurysm.
Left ventricular apical aneurysms, in absence of coronary artery disease, occur in approximately 1% of patients with hypertrophic cardiomyopathy (HC). Identical twins, age 44 years, are presented with HC and identical LV morphology, including apical aneurysms. These cases demonstrate a genetic predisposition to the development of apical aneurysm, as well as overall LV morphology, in patients with HC.
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Andrey G
AG
Zenovich
John R
JR
Lesser
Connie A
CA
Hanna
Barry J
BJ
Maron
D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D004200:Diseases in Twins; D005260:Female; D006322:Heart Aneurysm / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006352:Heart Ventricles; D006801:Humans; D014430:Twins, Monozygotic