Rescue therapy in septic shock--is terlipressin the last frontier?
Use of terlipressin, an analogue of vasopressin, can be considered in septic shock patients with intractable hypotension and high cardiac output in whom fluid resuscitation and high-dose conventional catecholamines have failed. The effects of this agent on organ function are poorly evaluated in humans. The limited number of patients evaluated precludes any analysis of adverse outcomes and prognosis.
Leone
Marc
M
Intensive Care Unit and Trauma Center, Nord University Hospital, Marseilles School of Medicine, Marseilles, France.
Martin
Claude
C
D000818:Animals; D006801:Humans; D008236:Lypressin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D012772:Shock, Septic / Q000188:drug therapy* / Q000453:epidemiology; D000077585:Terlipressin
D008236:Lypressin; D000077585:Terlipressin