Genetic control of hippocampal neurogenesis.
Adult neurogenesis in the hippocampus is under complex genetic control. A recent comparative study of two inbred mouse strains using quantitative trait locus analysis has revealed that cell survival is most highly correlated with neurogenesis and identified candidate genes for further investigation.
Department of Neurology, Programs in Neuroscience and Developmental Biology, University of California, San Francisco, CA 94143, USA.
Christine D
CD
Pozniak
Samuel J
SJ
Pleasure
D000818:Animals; D006624:Hippocampus / Q000254:growth & development*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C / Q000235:genetics*; D008810:Mice, Inbred C57BL / Q000235:genetics*; D009474:Neurons / Q000502:physiology*; D040641:Quantitative Trait Loci