Continuous veno-venous haemodiafiltration in sodium valproate overdose complicated by cerebral oedema: a case report.
A case of severe sodium valproate overdose is presented in which continuous venovenous haemodiafiltration was used. However, following the commencement of dialysis and a fall in the serum valproate levels, the patient developed cerebral oedema. This case demonstrated a poor correlation between serum valproate and its toxic effects and the lack of benefit of continuous venovenous haemodiafiltration in the management of sodium valproate overdose.
Intensive Care Unit, Royal Perth Hospital, Perth, Western Australia. lonmoney@iprimus.com.au
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