Rib fractures in chronic alcoholic men: Relationship with feeding habits, social problems, malnutrition, bone alterations, and liver dysfunction.
Rib fractures are common in alcoholics. This high prevalence might be due to ethanol-associated malnutrition, bone disease, liver dysfunction, or the peculiar lifestyle of the alcoholic with frequent trauma and altercations. In this study we try to discern the role of these factors on rib fracture (assessed on a plain thoracic X-ray film) in 81 consecutive alcoholic patients, 25 of them cirrhotics. Serum albumin, prothrombin aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), gamma-glutamyl transpeptidase, C-terminal cross-linking telopeptide of type 1 collagen, osteocalcin, insulin growth factor 1, 1,25-dihydroxyvitamin D, parathyroid hormone, estradiol, free testosterone, and corticosterone were measured, and the patients also underwent assessment of bone mineral density by a HOLOGIC QDR-2000 bone densitometer (Waltham, MA, USA). Body mass index, triceps skinfold, and brachial perimeter were also determined, and the patients and their families were asked about tobacco consumption, social and familial links, consumption of ethanol by other members of the family, kind of job, and feeding habits. Forty-two male nondrinker sanitary workers of similar age served as controls. Forty of the 81 patients showed rib fractures. There was a statistically significant association between rib fractures and disruption of social and familial links, irregular feeding habits (in bars or pubs, not at home), ethanol consumption by close relatives, and intensity of tobacco consumption, but not between rib fractures and liver function tests, nutritional parameters, or bone mineral density, besides a nearly significant trend (p = .053) with the presence of osteopenia at the femoral neck. Patients with major withdrawal symptoms at admission also presented more frequent rib fractures. We conclude that rib fractures in alcoholics are related to the peculiar lifestyle of these patients rather than to bone alterations, liver dysfunction, or nutritional status.
Servicios de Medicina Interna, Hospital Universitario, Universidad de La Laguna, Ofra s/n, Tenerife, Canary Islands, Spain. egonrey@ull.es
Emilio
E
González-Reimers
Elena
E
García-Valdecasas-Campelo
Francisco
F
Santolaria-Fernández
Antonio
A
Milena-Abril
Eva
E
Rodríguez-Rodríguez
Antonio
A
Martínez-Riera
Alina
A
Pérez-Ramírez
María Remedios
MR
Alemán-Valls
D015502:Absorptiometry, Photon; D000328:Adult; D000437:Alcoholism / Q000453:epidemiology* / Q000473:pathology / Q000523:psychology; D015415:Biomarkers; D015519:Bone Density / Q000187:drug effects / Q000502:physiology; D001842:Bone and Bones / Q000473:pathology*; D005247:Feeding Behavior; D006801:Humans; D008019:Life Style; D008108:Liver Diseases, Alcoholic / Q000453:epidemiology* / Q000473:pathology*; D008111:Liver Function Tests; D016015:Logistic Models; D008297:Male; D044342:Malnutrition / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D008875:Middle Aged; D009752:Nutritional Status; D015675:Osteocalcin / Q000378:metabolism; D012253:Rib Fractures / Q000453:epidemiology* / Q000473:pathology; D012919:Social Behavior; D012923:Social Class; D012944:Social Support
D015415:Biomarkers; D015675:Osteocalcin