Poststreptococcal syndrome uveitis: a descriptive case series and literature review.
OBJECTIVE
To describe the clinical features in a series of patients with poststreptococcal uveitis and to review literature on the pathophysiology and management.


METHODS
Retrospective and descriptive case series.


METHODS
Ten consecutive cases of poststreptococcal syndrome uveitis diagnosed between 1996 and 2003.


METHODS
Review of patient case notes.


METHODS
Age, laterality, clinical features, and anti-streptococcal lysin O titers.


RESULTS
Ten consecutive cases of poststreptococcal syndrome uveitis were identified. All our cases had bilateral nongranulomatous inflammation and raised anti-streptococcal lysin O titers. Collating data from previous reports and this series showed that 96% of the patients were below 40 years of age, and 87.5% had evidence of previous streptococcal infection. One third of the patients had posterior segment involvement. In our patients, this was in the form of vitritis, focal retinitis, optic disc swelling, and multifocal choroiditis.


CONCLUSIONS
Poststreptococcal syndrome uveitis should be considered in the etiology of acute bilateral nongranulomatous uveitis in children and young patients.
Calderdale Royal Hospital, Halifax, United Kingdom.
Shafiq
S
Ur Rehman
Seema
S
Anand
Aravind
A
Reddy
Oliver C
OC
Backhouse
Moin
M
Mohamed
Ishtiyak
I
Mahomed
Arthur D
AD
Atkins
Teifi
T
James
D000293:Adolescent; D000328:Adult; D000989:Antistreptolysin / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002833:Choroiditis / Q000276:immunology / Q000382:microbiology*; D005128:Eye Diseases / Q000276:immunology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D010211:Papilledema / Q000276:immunology / Q000382:microbiology; D012173:Retinitis / Q000276:immunology / Q000382:microbiology*; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000276:immunology / Q000382:microbiology*; D013577:Syndrome; D014605:Uveitis / Q000276:immunology / Q000382:microbiology*; D014822:Vitreous Body / Q000276:immunology / Q000382:microbiology*
D000989:Antistreptolysin