The effect of anchoring suture on the anastomotic blood flow in a rat model of human esophagojejunostomy.
OBJECTIVE
An impairment of anastomotic blood flow (ABF) and the resulting hypoxia readily lead to the complications such as leakage and stricture. We performed an animal study to evaluate the effect of anchoring suture for minimizing the impairment of ABF caused by tensile loading.


METHODS
An end-to-side jejunojejunostomy was done in 20 rats, and this followed the modeling of a human end-to-side esophagojejunostomy. Laser Doppler flowmetry was checked in three different tensile conditions to evaluate the influence of anchoring suture on the ABF.


RESULTS
Before anchoring suture, the mean ABF was 129.06 perfusion unit (PU), 96.99 PU, and 69.04 PU, in the order of tensile stress. After anchoring suture, the mean ABF was 121.68, 103.30, and 87.06 PU (P < 0.01).


CONCLUSIONS
Anchoring suture is a novel method to reduce the impairment of the anastomotic blood flow that is caused by tension.
Department of Surgery, Chosun University College of Medicine, Gwangju, Korea.
Seong-Pyo
SP
Mun
Seong-Hwan
SH
Kim
Chang-Hoon
CH
Song
Young-Don
YD
Min
D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D001783:Blood Flow Velocity; D004947:Esophagus / Q000601:surgery*; D007582:Jejunostomy / Q000379:methods; D007583:Jejunum / Q000601:surgery*; D017078:Laser-Doppler Flowmetry; D023421:Models, Animal; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D013718:Tensile Strength