The occurrence of systemic lupus erythematosus in an asymptomatic carrier of human T-cell lymphotropic virus type I.
A 63-year-old asymptomatic carrier of human T-cell lymphotropic virus type I (HTLV-1) infection was admitted because of chest oppression, a high-grade fever, polyarthralgia, and erythematous rashes. Laboratory examination revealed lymphocytopenia, proteinuria, and high titers of antinuclear antibodies and antidouble-stranded DNA antibody; thus, she was diagnosed as having systemic lupus erythematosus (SLE). This case indicates that HTLV-1 infection might be related with the pathogenesis of SLE.
The Department of Internal Medicine, Shiga University of Medical Science, Seta, Otsu, Shiga, 520-2192, Japan. toshiro@belle.shiga-med.ac.jp
Toshiro
T
Sugimoto
Mihoko
M
Okamoto
Tetsuro
T
Koyama
Hiroyuki
H
Takashima
Mitsuo
M
Saeki
Atsunori
A
Kashiwagi
Minoru
M
Horie
D002353:Carrier State / Q000821:virology*; D005260:Female; D015490:HTLV-I Infections / Q000150:complications*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000821:virology*; D008875:Middle Aged