The impact of atopy, sinus opacification, and nasal patency on quality of life in patients with severe nasal polyposis.
OBJECTIVE
Nasal polyposis has a great impact on the quality of life. The aim of this study was to evaluate the association between quality of life and atopy, sinus opacification, and nasal patency in severe nasal polyposis.


METHODS
One hundred nine patients completed the Medical Outcome Study Short Form-36 (SF-36) survey. Symptoms, polyp size, atopy, nasal patency, and sinus opacification were also scored.


RESULTS
Patients showed worse scores in all SF-36 domains, except for physical functioning, compared with Spanish population. Atopic patients had worse scores in role physical, body pain, vitality, and mental health than nonatopic patients. Atopic patients showed lower physical component summary (44.7 +/- 1.1) and mental component summary (38.4 +/- 1.0) than nonatopic patients (48.3 +/- 1.6, 40.6 +/- 1.3; P < 0.05), respectively. There were no correlations between quality of life and symptoms, polyp size, CT scan, nasal patency, and atopy.


CONCLUSIONS
Nasal polyposis has a considerable impact on quality of life and atopy worsens this impact.


METHODS
C-4.
Rhinology Unit, Department of Otorhinolaryngology (ICEMEQ), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain. 32874iao@comb.es
Isam
I
Alobid
Pedro
P
Benítez
Antonio
A
Valero
Joan
J
Berenguer
Manuel
M
Bernal-Sprekelsen
Cesar
C
Picado
Joaquim
J
Mullol
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D009298:Nasal Polyps / Q000150:complications / Q000000981:diagnostic imaging / Q000523:psychology*; D011788:Quality of Life; D012189:Retrospective Studies; D012221:Rhinitis, Allergic, Perennial / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D012720:Severity of Illness Index; D012882:Skin Tests; D014057:Tomography, X-Ray Computed