Oral alendronate therapy for severe vitamin D intoxication of the infant with nephrocalcinosis.
Vitamin D intoxication is a well-known cause of hypercalcemia in children. We report here the use of oral alendronate for the treatment of hypercalcemia due to vitamin D intoxication in a 7 month-old infant with nephrocalcinosis. The serum calcium levels were normalized without complications. Oral alendronate therapy may be safely used in hypercalcemia due to vitamin. D intoxication in pediatric patients with nephrocalcinosis resistant to hydration, diuretics or corticosteroids.
Atabek
Mehmet Emre
ME
Department of Pediatrics, Section of Pediatric Endocrinology, School of Medicine, Selcuk University, Konya, Turkey. meatabek@hotmail.com
Pirgon
Ozgur
O
Sert
Ahmet
A
D000284:Administration, Oral; D019386:Alendronate / Q000008:administration & dosage*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D062787:Drug Overdose; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced / Q000188:drug therapy*; D007223:Infant; D009397:Nephrocalcinosis / Q000139:chemically induced / Q000188:drug therapy*; D012279:Rickets / Q000188:drug therapy; D016896:Treatment Outcome; D014807:Vitamin D / Q000506:poisoning*
D050071:Bone Density Conservation Agents; D014807:Vitamin D; D019386:Alendronate