Inflammatory pseudotumor of the cavernous sinus and skull base.
Inflammatory pseudotumor is a non-neoplastic process of unknown etiology characterized by a proliferation of connective tissue with an inflammatory infiltrate. Intracranial inflammatory pseudotumors classically involve the cavernous sinus but can also occur in the supratentorial or infratentorial compartments and spinal canal. Symptoms are dependent on location, and, when present in the cavernous sinus, typically include cranial nerve palsies of those nerves in the cavernous sinus. These lesions are rapidly responsive to steroid therapy. Surgery is typically indicated for biopsy only, but complete resection may be justified for lesions outside the cavernous sinus.
Department of Neurosurgery, University of Utah, 30 North 1900 East, Suite 3B409, Salt Lake City, UT, 84132, USA.
Todd
T
McCall
Daniel R
DR
Fassett
George
G
Lyons
William T
WT
Couldwell
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002426:Cavernous Sinus / Q000473:pathology*; D006104:Granuloma, Plasma Cell / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D019291:Skull Base / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D011241:Prednisone