Successful treatment of septic shock due to pan-resistant Acinetobacter baumannii using combined antimicrobial therapy including tigecycline.
Reported here is the case of a patient with septic shock due to multidrug-resistant Acinetobacter baumannii, which developed after complicated acute pancreatitis with intra-abdominal abscess. Treatment with colistin methanesulphonate and high doses of meropenem were initiated, but since shock persisted, tigecycline was added to the regimen, resulting in successful resolution of the infection.
Infectious Diseases Department, Erasme University Hospital, University of Brussels, Route de Lennik 808, 1070, Brussels, Belgium.
F S
FS
Taccone
H
H
Rodriguez-Villalobos
D
D
De Backer
V
V
De Moor
J
J
Deviere
J-L
JL
Vincent
F
F
Jacobs
D000151:Acinetobacter Infections / Q000150:complications / Q000188:drug therapy*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000302:isolation & purification; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003091:Colistin / Q000627:therapeutic use; D024901:Drug Resistance, Multiple, Bacterial; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D000077731:Meropenem; D008911:Minocycline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications; D012772:Shock, Septic / Q000188:drug therapy* / Q000453:epidemiology; D013845:Thienamycins / Q000627:therapeutic use; D000078304:Tigecycline; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000078304:Tigecycline; D000077731:Meropenem; D008911:Minocycline; D003091:Colistin