Lessons learned from gene therapy concerning and the use of integrating vectors and the possible risk of insertional oncogenesis.
Cichutek
K
K
Paul-Ehrlich-Institut, Langen, Germany. cick1@pei.de
D015316:Genetic Therapy / Q000009:adverse effects*; D005822:Genetic Vectors / Q000009:adverse effects*; D006801:Humans; D009052:Leukemia Virus, Murine / Q000235:genetics; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D016511:Severe Combined Immunodeficiency / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000009:adverse effects; D019444:Vaccines, DNA / Q000009:adverse effects*; D014614:Vaccines, Synthetic / Q000009:adverse effects*
D019444:Vaccines, DNA; D014614:Vaccines, Synthetic