Alternative propellant aerosol delivery systems.
The year 2006 represents the 50th anniversary of the pressurized metered dose inhaler. With most technologies, 50 years represents a significant time span for technology evolution and modification, but with propellant-driven metered dose inhalers, the pace of change has been relatively slow. We are now in the era of alternative propellant aerosol delivery systems, but at this 50-year juncture, what are the characteristics of these systems and what are the prospects for future advances? This review will consider alternative propellant aerosol delivery systems broadly from their inception through future opportunities and challenges.
Smyth
Hugh D C
HD
College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Leach
Chet L
CL
D000336:Aerosols; D004333:Drug Administration Routes; D006801:Humans
D000336:Aerosols