[Work-related asthma caused by IgE-verified allergy to methylene di-isocynate].
A 44-year-old blacksmith periodically exposed to methylene di-isocynate (MDI) from foaming processes over the course of eight years developed an acute episode of asthma shortly after high exposure to MDI. The respiratory symptoms declined gradually over some months. A year later the specific IgE to MDI was still high (23.92 KU/l), but lung function (FEV1, PEF and FVC) was normal and no bronchial hyperreactivity was observed. He is still working at the same factory under respiratory health surveillance.
Arhus Universitetshospital, Aalborg Sygehus, Arbejdsmedicinsk Klinik, Aalborg. rudbeck@dadlnet.dk
Marianne Grau
MG
Rudbeck
Oyvind
O
Omland
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced*; D003485:Cyanates / Q000009:adverse effects*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced*; D017953:Isocyanates; D008176:Lung Volume Measurements; D008297:Male; D008669:Metallurgy; D009784:Occupational Diseases / Q000139:chemically induced*
D000395:Air Pollutants, Occupational; D003485:Cyanates; D017953:Isocyanates; C059330:methylene diisocyanate