Chlamydomonas agglutinin is a hydroxyproline-rich glycoprotein.
The mt(+) sexual agglutinin from Chlamydomonas reinhardi is shown to contain approximately 12% hydroxyproline, and two inhibitors of hydroxyproline formation, alpha,alpha'-dipyridyl and 3,4-dehydroproline, are shown to block the production of agglutinin activity in an in vivo bioassay system. These results indicate that the agglutinin glycoprotein may be related to a class of hydroxyproline-rich glycoproteins found in the extracellular matrix of higher plants, several of which have been shown to have lectin activity.
Cooper
J B
JB
Department of Biology, Washington University, Washington University School of Medicine, St. Louis, Missouri 63130.
Adair
W S
WS
Mecham
R P
RP
Heuser
J E
JE