Antioxidant activity of diterpenes and polyphenols from Ophryosporus heptanthus.
The antioxidant activity of 14 compounds (1-14) isolated from the ether and butanolic extracts of the aerial parts of Ophryosporus heptanthus has been assayed using a beta-carotene bleaching method and the DPPH technique. Compounds 1 and 13 showed the most potent antioxidant activity. Their structures have been established by spectroscopic techniques (mainly NMR). Compounds 7 and 12 are new natural products, and their structures have been confirmed by chemical synthesis.
Barrero
Alejandro F
AF
Departamento de Química Organica, Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva, s/n, 18071 Granada, España. afbarre@ugr.es
Herrador
M Mar
MM
Arteaga
Pilar
P
Rosas-Romero
Alfredo
A
Arteaga
Jesús F
JF
D000975:Antioxidants / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D059808:Polyphenols
D000975:Antioxidants; D004224:Diterpenes; D005419:Flavonoids; D010636:Phenols; D059808:Polyphenols