Enantioselective organocatalytic Michael addition reactions between N-heterocycles and nitroolefins.
[reaction: see text] A method for Michael addition of N-heterocycles to nitroolefins has been developed. The process is promoted by a cinchona alkaloid derivative to give Michael adducts in moderate to high enantioselectivities.
Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA.
Jian
J
Wang
Hao
H
Li
Liansuo
L
Zu
Wei
W
Wang
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D002930:Cinchona Alkaloids; D009574:Nitro Compounds