[Hairy cell leukemia in pregnancy].
Pregnancy complicated by HCL is an extremlely rare event: only 5 report of HCL in pregnancy have been previously described. A 36-year-old women was diagnosed of HCL presented in 14 week of her 5th pregnancy. Therapy was initiated in 18 wk of gestation with IFN-alpha at dose 6 x 106 U subcutaneous 3 times per week and prednisone 20 mg/d. IFN-alpha administration was well tolerated. After IFN-alpha therapy partial remission was achieved. The course of the pregnancy was normal. At week 39 of gestation a cesarean cection was performed and the patient delivered a healthy male infant weighing 3460 g with Apgar score of 10. The placenta was of normal size, no infiltration of hairy cell was founded. Post-partum course was uncomplicated. The patient elected to not breast feed her infant. 3 weeks after delivery patient had a 5-days course of 2CDA
Kopeć
Izabella
I
Instytut Hematologii i Transfuzjologii w Warszawie.
Debski
Romuald
R
Samsel
Marzena
M
Winter
Waldemar
W
Maryniak
Renata
R
Prochorec
Monika
M
Podstawka
Urszula
U
Maj
Stanisław
S
Banaczek
Zbigniew
Z
Warzocha
Krzysztof
K
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000008:administration & dosage; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000188:drug therapy*; D011256:Pregnancy Outcome
D000970:Antineoplastic Agents; D016898:Interferon-alpha; D011241:Prednisone