The bacteriologic yield in children with intrathoracic tuberculosis.
This report documents the bacteriologic yield in children who received treatment for intrathoracic tuberculosis in an area where it is highly endemic. A total of 307 children were included in the study, and bacteriologic confirmation was achieved in 122 (62.2%) of 196 children from whom specimens were collected. The lowest bacteriologic yield was recorded for the 69 children with uncomplicated lymph node disease (24 [34.8%] had bacteriologic confirmation). The high overall bacteriologic yield indicates the need to reassess the value of bacteriology-based approaches to diagnosis of intrathoracic tuberculosis in children, particularly in areas of endemicity where they frequently present with advanced disease.
Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Tygerberg Children's Hospital, Stellenbosch University, Cape Town, South Africa. bjmarais@sun.ac.za
B J
BJ
Marais
A C
AC
Hesseling
R P
RP
Gie
H S
HS
Schaaf
D A
DA
Enarson
N
N
Beyers
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D011446:Prospective Studies; D012137:Respiratory System / Q000382:microbiology; D013019:South Africa; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*