[Effect of pricking blood therapy at Ashi points on peripheral pain mediums in the acute gouty arthritis rat].
OBJECTIVE
To study the analgesic mechanism of pricking blood therapy at Ashi points in the acute gouty arthritis rat.


METHODS
Forty rats were randomly divided into a blank group, a model group, an indomethacin group and a pricking blood group. Except the blank group, other groups were injected with sodium urate liquor into the ankle cavity to develop the acute gouty arthritis rat model, and the indomethacin group received gastric perfusion of indomethacin, and the pricking blood group were treated with pricking blood therapy at Ashi points. The peripheral pain mediums K+, NE, DA, (5-HT contents were determined.


RESULTS
The K+, DA, 5-HT contents in the pricking blood group decreased significantly as compared with the model group (P < 0.01, P < 0.05); there was no significant difference in the content of NE between the pricking blood group and the model group.


CONCLUSIONS
Pricking blood at Ashi points can effectively inhibit release of the peripheral pain mediums K+, DA and 5-HT.
Li
Tong
T
Chengdu University of TCM, Sichuan 610075, China. carllitong@163.com
Xie
Yi-qiang
YQ
Li
Sheng-cai
SC
Huang
Di-jun
DJ
D000818:Animals; D015210:Arthritis, Gouty / Q000628:therapy; D010146:Pain; D051381:Rats; D013270:Stomach