Feasibility of duct-to-duct biliary reconstruction in pediatric living related liver transplantation: report of three cases.
Feasibility of duct-to-duct biliary reconstruction in adult living related liver transplantation (LRLTx) has been recently reported; however, little has been known of its surgical outcome in children. To assess the feasibility and safety of duct-to-duct biliary reconstruction in children, the surgical outcomes of duct-to-duct biliary reconstruction were retrospectively analyzed. The subjects were three children who underwent LRLTx in our hospital each utilizing allografts with a right lobe, a left robe and a lateral segment, respectively. The cause of end-stage liver disease in each of them was fulminant Wilson's disease, fulminant hepatic failure and unresectable hepatoblastoma. Duct-to-duct anastomosis was performed in younger patients and adolescents with interrupted and continuous sutures, respectively. The diameter of bile duct in allografts was from 4 to 6 mm and 12 or 13 stitches were required for anastomosis. Post-operative choledochography from the external tube showed neither stenosis nor leakage and the tube was evacuated within 3 months after LRLTx. No biliary complications were observed with the median follow-up of 28 months. In conclusion, our results show that duct-to-duct biliary reconstructions in pediatric LRLTx seemed to be feasible and safe. Further studies are required to elucidate its real impact on pediatric LRLTx.
Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. kimutaku@pedsurg.med.osaka-u.ac.jp
Takuya
T
Kimura
Toshimichi
T
Hasegawa
Yoshiyuki
Y
Ihara
Keigo
K
Nara
Takashi
T
Sasaki
Keizo
K
Dono
Sotarou
S
Mushiake
Masahiro
M
Fukuzawa
D000293:Adolescent; D000714:Anastomosis, Surgical; D001652:Bile Ducts / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005240:Feasibility Studies; D005260:Female; D018197:Hepatoblastoma / Q000601:surgery; D006527:Hepatolenticular Degeneration / Q000601:surgery; D006801:Humans; D017114:Liver Failure, Acute / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D012189:Retrospective Studies; D013536:Suture Techniques; D014184:Transplantation, Homologous