Proteomic profiling of human urine using multi-dimensional protein identification technology.
Human urine samples are ideal for proteomic profiling and have tremendous potential as sources of biomarkers. Multi-dimensional protein identification technology (MudPIT) is an effective approach to analyzing human urine or other fluids dominated by diverse metabolites. MudPIT analysis was used to identify 87 proteins in just 15 ml of human urine. A high throughput, reproducible, and sensitive technology, MudPIT may soon be used for more proteomic analyses of metabolites.
Windber Research Institute, PA 15963, USA. c.ru@wriwindber.org
Qinhua Cindy
QC
Ru
Richard A
RA
Katenhusen
Luwang Andy
LA
Zhu
Jordan
J
Silberman
Song
S
Yang
Trevor J
TJ
Orchard
Henry
H
Brzeski
Michael
M
Liebman
Darrell L
DL
Ellsworth
D006801:Humans; D011507:Proteinuria / Q000378:metabolism*; D020543:Proteome
D020543:Proteome