Proteomic profiling of human urine using multi-dimensional protein identification technology.
Human urine samples are ideal for proteomic profiling and have tremendous potential as sources of biomarkers. Multi-dimensional protein identification technology (MudPIT) is an effective approach to analyzing human urine or other fluids dominated by diverse metabolites. MudPIT analysis was used to identify 87 proteins in just 15 ml of human urine. A high throughput, reproducible, and sensitive technology, MudPIT may soon be used for more proteomic analyses of metabolites.
Ru
Qinhua Cindy
QC
Windber Research Institute, PA 15963, USA. c.ru@wriwindber.org
Katenhusen
Richard A
RA
Zhu
Luwang Andy
LA
Silberman
Jordan
J
Yang
Song
S
Orchard
Trevor J
TJ
Brzeski
Henry
H
Liebman
Michael
M
Ellsworth
Darrell L
DL
D006801:Humans; D011507:Proteinuria / Q000378:metabolism*; D020543:Proteome
D020543:Proteome