Meiosis: checking chromosomes pair up properly.
Faithful recombination and chromosome segregation in meiosis require regulated steps of homolog recognition and association which are monitored by meiotic checkpoints. A recent study in the nematode Caenorhabditis elegans has identified a checkpoint mechanism that monitors chromosome pairing during meiosis.
Meier
Bettina
B
Division of Gene Regulation and Expression, School of Life Sciences, University of Dundee, Scotland, UK.
Gartner
Anton
A
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D017173:Caenorhabditis elegans / Q000166:cytology / Q000235:genetics*; D023902:Chromosome Pairing / Q000502:physiology*; D004249:DNA Damage; D005260:Female; D005854:Germ Cells / Q000166:cytology / Q000502:physiology; D008297:Male; D008540:Meiosis / Q000235:genetics*; D009154:Mutation; D049471:Pachytene Stage / Q000502:physiology; D011995:Recombination, Genetic