A randomized, double-blind trial of bromocriptine efficacy in nonfluent aphasia after stroke.
The authors assessed the efficacy of bromocriptine in nonfluent aphasia after stroke in a 16-week, randomized, double-blind, placebo-controlled clinical trial conducted from June 2002 to April 2004. In all 38 patients after 4 months of treatment, improvement in both the bromocriptine and placebo treatment groups was observed (p < 0.001). The analysis of repeated-measures analysis of variance revealed bromocriptine did not improve nonfluent aphasia.
Department of Neurology and Epidemiology, Isfahan University of Medical Sciences and Health Services, Iran.
F
F
Ashtary
M
M
Janghorbani
A
A
Chitsaz
M
M
Reisi
A
A
Bahrami
D000328:Adult; D000368:Aged; D001039:Aphasia, Broca / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D001971:Bromocriptine / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007807:Language Tests; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology
D001971:Bromocriptine