Oligomers of cis-beta-norbornene amino acid: formation of beta-strand mimetics.
The oligomers of constrained cis-exo-beta-norbornene amino acid were synthesised and characterised by extensive NMR, CD, IR and MD studies. The results showed the formation of both right and left handed consecutive 6-membered hydrogen-bonded strands for [2S,3R] and [2R,3S] enantiomers, respectively.
Chandrasekhar
Srivari
S
Division of Organic Chemical Sciences, Indian Institute of Chemical Technology, Hyderabad, India. srivaric@iict.res.in
Babu
Bathini Nagendra
BN
Prabhakar
Anabathula
A
Sudhakar
Ambadi
A
Reddy
Marepally Srinivasa
MS
Kiran
Marelli Udaya
MU
Jagadeesh
Bharatam
B
D000596:Amino Acids / Q000737:chemistry*; D032701:Biomimetics; D006860:Hydrogen Bonding; D009636:Norbornanes / Q000737:chemistry*; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D017433:Protein Structure, Secondary; D013057:Spectrum Analysis; D013237:Stereoisomerism
D000596:Amino Acids; D009636:Norbornanes; D009842:Oligopeptides; C046060:2-norbornene