Recent advances in small animal genetics.
The whole genome sequence of the dog is complete, and partial sequencing of the cat genome is underway. Sequences allow the molecular basis for inherited diseases to be more easily determined, leading to development of DNA tests to verify carrier and affected states as well as potential gene therapy for the treatment of those diseases. To help veterinarians provide genetic services to their clients, the molecular genetic tests currently available are listed in this article. In addition, cloning of small animals is now available to clients on a commercial basis. Information about the cloning process and possible health issues in clones are discussed.
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, One Shields Avenue, University of California at Davis, Davis, CA 95616, USA. dlbannasch@ucdavis.edu
Danika L
DL
Bannasch
Angela M
AM
Hughes
D000818:Animals; D000831:Animals, Newborn / Q000235:genetics; D001947:Breeding; D002371:Cat Diseases / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D002415:Cats / Q000235:genetics*; D019976:Cloning, Organism / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D004285:Dogs / Q000235:genetics*; D015316:Genetic Therapy / Q000662:veterinary; D016678:Genome; D006579:Heterozygote