Oral alendronate therapy for severe vitamin D intoxication of the infant with nephrocalcinosis.
Vitamin D intoxication is a well-known cause of hypercalcemia in children. We report here the use of oral alendronate for the treatment of hypercalcemia due to vitamin D intoxication in a 7 month-old infant with nephrocalcinosis. The serum calcium levels were normalized without complications. Oral alendronate therapy may be safely used in hypercalcemia due to vitamin. D intoxication in pediatric patients with nephrocalcinosis resistant to hydration, diuretics or corticosteroids.
Department of Pediatrics, Section of Pediatric Endocrinology, School of Medicine, Selcuk University, Konya, Turkey. meatabek@hotmail.com
Mehmet Emre
ME
Atabek
Ozgur
O
Pirgon
Ahmet
A
Sert
D000284:Administration, Oral; D019386:Alendronate / Q000008:administration & dosage*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D062787:Drug Overdose; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced / Q000188:drug therapy*; D007223:Infant; D009397:Nephrocalcinosis / Q000139:chemically induced / Q000188:drug therapy*; D012279:Rickets / Q000188:drug therapy; D016896:Treatment Outcome; D014807:Vitamin D / Q000506:poisoning*
D050071:Bone Density Conservation Agents; D014807:Vitamin D; D019386:Alendronate