Heart rate-corrected QT interval duration is significantly associated with blood pressure in Chinese hypertensives.
BACKGROUND
Many studies demonstrated that a prolonged heart rate-corrected QT interval (QTc) increases the risk of malignant ventricular arrhythmias and sudden death.


METHODS
We measured the electrocardiogram and blood pressure of 1480 hypertensive patients and assessed the relationship between the length of QTc and blood pressure.


RESULTS
The mean QTc is longer in female than in male participants. There was a positive association between QTc and blood pressure in both men and women. The estimated increase in systolic and diastolic blood pressure for each 100-millisecond increase in QTc was 6.4 and 5.0 mm Hg in men and 3.7 and 2.5 mm Hg in women, respectively.


CONCLUSIONS
Our study demonstrated a significant positive relationship between the QTc interval and baseline blood pressure in a Chinese hypertensive population.
Institute of Biomedicine, Anhui Medical University, Hefei 230032, China.
Shaojie
S
Peng
Yunxian
Y
Yu
Ke
K
Hao
Houxun
H
Xing
Dong
D
Li
Changzhong
C
Chen
Aiqun
A
Huang
Xiumei
X
Hong
Yan
Y
Feng
Yan
Y
Zhang
Jianping
J
Li
Binyan
B
Wang
Di
D
Wu
Xiaobin
X
Wang
Xiping
X
Xu
D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D002681:China; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008133:Long QT Syndrome / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D011795:Surveys and Questionnaires