Intracranial aspergillosis in children successfully treated with antifungal therapy and surgical intervention.
Invasive aspergillosis is an uncommon but often lethal complication in immunocompromised patients. Despite the progress obtained with new antifungal drugs, intracranial aspergillosis often requires a combined medical and surgical approach. Most cases previously reported in immunocompromised children were fatal. We describe 4 immunosuppressed children with intracranial aspergillosis successfully treated with surgery and antifungal long-term therapy.
Department of Infectious Diseases, Immuno-Rheumatology and Onco-Hematology, University of Turin, Italy. mareva.giacchino@unito.it
Mareva
M
Giacchino
Nadia
N
Chiapello
Caterina
C
Riva
Carlo
C
Scolfaro
Mirco
M
Pultrone
Mariangela
M
Valera
Paola
P
Peretta
Matilde
M
Piglione
Gianpaolo
G
Di Rosa
Pier-Angelo
PA
Tovo
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D001232:Aspergillus fumigatus / Q000187:drug effects / Q000302:isolation & purification; D001927:Brain Diseases / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D000935:Antifungal Agents