Fetal-to-neonatal maladaptation.
Although the majority of newly born babies will establish normal respiratory and circulatory function without help, 1-2% might run into difficulties because of a disturbance in the normal adaptive processes required for a smooth transition from intrauterine to extrauterine life. An understanding of the normal and abnormal perinatal physiology is important to appreciate the practical differences in the approach to caring for such babies, and also for avoiding actions that might be detrimental in the longer term.
Sinha
Sunil K
SK
The James Cook University Hospital, University of Durham, Marton Road, Middlesborough TS4 3BW, UK. sunil.sinha@stees.nhs.uk
Donn
Steven M
SM
D000220:Adaptation, Biological; D001720:Birth Injuries / Q000209:etiology / Q000503:physiopathology; D001833:Body Temperature Regulation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology* / Q000628:therapy; D008168:Lung / Q000196:embryology / Q000502:physiology*; D007744:Obstetric Labor Complications / Q000209:etiology; D011247:Pregnancy; D012119:Respiration; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000628:therapy