Standardization of 18F by coincidence and LSC methods.
The nuclide 18F disintegrates to 18O by beta+ emission (96.86%) and electron capture (3.14%) with a half-life of 1.8288 h. It is widely used in nuclear medicine for positron emission tomography (PET). A radioactive solution of this nuclide has been standardized by two techniques: coincidence measurements with a pressurized proportional counter and liquid scintillation counting using the CIEMAT/NIST method. One ampoule containing a solution calibrated in activity was sent for measurement at the International Reference System maintained by the BIPM. Results are in excellent agreement with SIR values.
Roteta
Miguel
M
Laboratorio de Metrología de Radiaciones Ionizantes, CIEMAT, Avda. Complutense 22, 28040 Madrid, Spain.
García-Toraño
Eduardo
E
Rodríguez Barquero
Leonor
L
D002138:Calibration / Q000592:standards; D005462:Fluorine Radioisotopes / Q000032:analysis* / Q000592:standards*; D038622:Internationality; D009683:Nuclear Medicine / Q000592:standards*; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation* / Q000592:standards*; D019275:Radiopharmaceuticals / Q000032:analysis / Q000592:standards; D012015:Reference Standards; D012016:Reference Values; D015203:Reproducibility of Results; D012588:Scintillation Counting / Q000295:instrumentation* / Q000592:standards*; D012680:Sensitivity and Specificity
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals