Influence of the spatial position of a trifluoromethyl group on the 13C chemical shifts in the cyclohexane series.
The influence of the introduction of a trifluoromethyl group on the 13C chemical shifts in cyclohexane was examined. The two main effects observed are located at the alpha and gamma positions relative to the carbon bearing the fluorine atoms. By comparison of the collected data it was possible to calculate the increments corresponding to the substitution of a hydrogen atom by a CF3 group at axial or equatorial positions on the cyclohexane ring.
Carcenac
Yvan
Y
SIRCOB UMR CNRS 8086, Université de Versailles Saint Quentin en Yvelines, 45 avenue des Etats Unis-78035 Versailles, France.
Diter
Patrick
P
Wakselman
Claude
C
Tordeux
Marc
M