Relationship between Helicobacter pylori infection and Alzheimer disease.
The authors investigated the association between Helicobacter pylori infection (Hp-I) and Alzheimer disease (AD) by using histology for diagnosis of Hp-I. Fifty patients with AD and 30 iron deficiency anemic control participants without AD were included. The histologic prevalence of Hp-I was 88% in patients with AD and 46.7% in controls (p < 0.001).
Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Greece. jannis@med.auth.gr
J
J
Kountouras
M
M
Tsolaki
E
E
Gavalas
M
M
Boziki
C
C
Zavos
P
P
Karatzoglou
D
D
Chatzopoulos
I
I
Venizelos
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D005773:Gastroscopy / Q000592:standards; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology* / Q000473:pathology*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged