A time series analysis of the relationship of ambient temperature and common bacterial enteric infections in two Canadian provinces.
The incidence of enteric infections in the Canadian population varies seasonally, and may be expected to be change in response to global climate changes. To better understand any potential impact of warmer temperature on enteric infections in Canada, we investigated the relationship between ambient temperature and weekly reports of confirmed cases of three pathogens in Canada: Salmonella, pathogenic Escherichia coli and Campylobacter, between 1992 and 2000 in two Canadian provinces. We used generalized linear models (GLMs) and generalized additive models (GAMs) to estimate the effect of seasonal adjustments on the estimated models. We found a strong non-linear association between ambient temperature and the occurrence of all three enteric pathogens in Alberta, Canada, and of Campylobacter in Newfoundland-Labrador. Threshold models were used to quantify the relationship of disease and temperature with thresholds chosen from 0 to -10 degrees C depending on the pathogen modeled. For Alberta, the log relative risk of Salmonella weekly case counts increased by 1.2%, Campylobacter weekly case counts increased by 2.2%, and E. coli weekly case counts increased by 6.0% for every degree increase in weekly mean temperature. For Newfoundland-Labrador the log relative risk increased by 4.5% for Campylobacter for every degree increase in weekly mean temperature.
Foodborne, Waterborne and Zoonotic Infections Division, Public Health Agency of Canada, 160 Research Lane, Unit 206, Guelph, Ontario, N1G 5B2, Canada. Manon_D_Fleury@phac-aspc.gc.ca
Manon
M
Fleury
Dominique F
DF
Charron
John D
JD
Holt
O Brian
OB
Allen
Abdel R
AR
Maarouf
D000416:Alberta / Q000453:epidemiology; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology*; D006801:Humans; D007410:Intestinal Diseases / Q000453:epidemiology* / Q000382:microbiology*; D009523:Newfoundland and Labrador / Q000453:epidemiology; D013696:Temperature