Diagnosis and management of bilateral posterior lenticonus in 7 members of the same family.
OBJECTIVE
To report on the occurrence of monosymptomatic bilateral posterior lenticonus in 7 members of the same family and discuss the diagnoses and methods of management.


METHODS
Eye Clinic, Cantonal Hospital, Lucerne, Switzerland.


METHODS
Two sisters were found to suffer from bilateral posterior lenticonus. The 3 sons of the elder sister and the 2 daughters of the younger sister all presented with bilateral posterior lenticonus. A cataract operation or a clear lens extraction with intraocular lens implantation was performed in 4 of the 7 patients.


RESULTS
The disorder was found to be inherited and to follow a pattern of autosomal dominance. Visual acuity improved to 20/20 in all operated eyes.


CONCLUSIONS
This may be the largest group in 1 family presenting with bilateral posterior lenticonus described to date. Treatment of posterior lenticonus, if necessary, can be successfully managed as an ordinary cataract.
Schipper
Isaak
I
Eye Clinic, Cantonal Hospital, Lucerne, Switzerland. i.schipper@tic.ch
Senn
Peter
P
Schmid
Martin
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D007839:Functional Laterality; D005799:Genes, Dominant; D006801:Humans; D007905:Lens Diseases / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery*; D019654:Lens Implantation, Intraocular; D008297:Male; D010375:Pedigree; D018918:Phacoemulsification; D014792:Visual Acuity