Chlamydomonas agglutinin is a hydroxyproline-rich glycoprotein.
The mt(+) sexual agglutinin from Chlamydomonas reinhardi is shown to contain approximately 12% hydroxyproline, and two inhibitors of hydroxyproline formation, alpha,alpha'-dipyridyl and 3,4-dehydroproline, are shown to block the production of agglutinin activity in an in vivo bioassay system. These results indicate that the agglutinin glycoprotein may be related to a class of hydroxyproline-rich glycoproteins found in the extracellular matrix of higher plants, several of which have been shown to have lectin activity.
Department of Biology, Washington University, Washington University School of Medicine, St. Louis, Missouri 63130.
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JB
Cooper
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WS
Adair
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Mecham
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JE
Heuser