[Lymphocytes B and NK in respiratory allergy].
BACKGROUND
High affinity immunoglobulin E (IgE) receptors may activate the mast cell degradation; on the other hand, the ones of low affinity may activate B lymphocytes so they act as antigen-presenting cells and as producers of the same immunoglobulin. As allergic patients produce a great quantity of IgE they are prone to get an infection.


OBJECTIVE
To quantify the IgE increase in 28 patients with allergic rhinitis or asthma, or both without having received a previous treatment.


METHODS
38 patients with allergic rhinitis, bronchial asthma, allergic conjunctivitis or atopic dermatitis diagnosis were included. B lymphocytes and NK cells immunophenotypification was made. Flow cytometry was used for cells lecture. Data were analyzed with descriptive statistics applying central tendency measurements.


RESULTS
No variations were found in the values of any cell lineage.


CONCLUSIONS
Proliferation and activation of B lymphocytes should be considered in allergic diseases as its quantification in serum may be a measurement parameter of allergic activity.
Servicio de alergia e inmunología, Hospital Juárez de México.
Daniel
D
Aguilar Angeles
Ma Isabel
MI
Rojo Gutiérrez
Karina Elvira
KE
López Valladares
Teresa
T
Sandoval
Mario Alberto
MA
Bermejo Guevara
Misael
M
González Ibarra
D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012130:Respiratory Hypersensitivity / Q000097:blood* / Q000276:immunology*