Utility of Ictal SPECT in the presurgical evaluation of Rasmussen's encephalitis.
BACKGROUND
Rasmussen's encephalitis is a progressive disease characterized by severe progressive neurological and cognitive deficits. It is a difficult condition to treat with conventional medical treatment and requires, in most of the cases, surgical intervention.


METHODS
We present the case of a patient with Rasmussen's encephalitis who presented with epilepsia partialis continua, who did not respond to antiepileptic treatment and was evaluated for possible surgical intervention.


RESULTS
The electroencephalographic studies revealed bihemispheric involvement during seizures, although magnetic resonance imaging (MRI) showed a marked right hemispheric atrophy. Hyperperfusion over the right hemisphere was seen with the performance of ictal single photon emission computed tomography (SPECT), which finally guided a right functional hemispherectomy and subsequent seizure control.


CONCLUSIONS
Ictal SPECT could be a useful tool in the armamentarium of tools used for the localization of the epileptogenic focus in patients with Rasmussen's encephalitis and other localization-related epilepsies.
Epilepsy Programme, University of Western Ontario, London, Canada.
Jorge G
JG
Burneo
Margaret
M
Hamilton
William
W
Vezina
Andrew
A
Parrent
D000328:Adult; D001921:Brain / Q000473:pathology; D004569:Electroencephalography; D004660:Encephalitis / Q000175:diagnosis* / Q000601:surgery; D017036:Epilepsia Partialis Continua / Q000209:etiology; D005260:Female; D038421:Hemispherectomy; D006801:Humans; D008279:Magnetic Resonance Imaging; D010091:Oximes; D012640:Seizures / Q000209:etiology; D015899:Tomography, Emission-Computed, Single-Photon
D010091:Oximes; C068296:hexamethylpropyleneamine oxime