Standardization of 18F by coincidence and LSC methods.
The nuclide 18F disintegrates to 18O by beta+ emission (96.86%) and electron capture (3.14%) with a half-life of 1.8288 h. It is widely used in nuclear medicine for positron emission tomography (PET). A radioactive solution of this nuclide has been standardized by two techniques: coincidence measurements with a pressurized proportional counter and liquid scintillation counting using the CIEMAT/NIST method. One ampoule containing a solution calibrated in activity was sent for measurement at the International Reference System maintained by the BIPM. Results are in excellent agreement with SIR values.
Laboratorio de Metrología de Radiaciones Ionizantes, CIEMAT, Avda. Complutense 22, 28040 Madrid, Spain.
Miguel
M
Roteta
Eduardo
E
García-Toraño
Leonor
L
Rodríguez Barquero
D002138:Calibration / Q000592:standards; D005462:Fluorine Radioisotopes / Q000032:analysis* / Q000592:standards*; D038622:Internationality; D009683:Nuclear Medicine / Q000592:standards*; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation* / Q000592:standards*; D019275:Radiopharmaceuticals / Q000032:analysis / Q000592:standards; D012015:Reference Standards; D012016:Reference Values; D015203:Reproducibility of Results; D012588:Scintillation Counting / Q000295:instrumentation* / Q000592:standards*; D012680:Sensitivity and Specificity
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals