Isolated central diabetes insipidus in a newborn with congenital toxoplasmosis.
We present a 5 day-old male newborn with isolated central diabetes insipidus due to congenital toxoplasmosis. This patient was referred to us for hydrocephalus. As we investigated the aetiology of the hydrocephalus, the patient's serum and cerebrospinal fluid tested positive for toxoplasmosis via ELISA and polymerase chain reaction. Computed tomography showed obstructive hydrocephalus and disseminated cranial calcifications. Central diabetes insipidus developed on the 10th day, apparently as a result of the toxoplasmosis infection, and was treated successfully with oral desmopressin.
Department of Paediatrics, Division of Neonatology, Fatih University School of Medicine, Ankara, Turkey. ahmetkaradag@gmail.com
Ahmet
A
Karadag
Omer
O
Erdeve
Begum
B
Atasay
Saadet
S
Arsan
Gulhis
G
Deda
Erdal
E
Ince
Gonul
G
Ocal
Merih
M
Berberoglu
D000284:Administration, Oral; D050034:Antidiuretic Agents / Q000008:administration & dosage*; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage*; D003919:Diabetes Insipidus / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000150:complications*; D007231:Infant, Newborn; D008297:Male; D014057:Tomography, X-Ray Computed; D014125:Toxoplasmosis, Congenital / Q000150:complications* / Q000175:diagnosis; D016896:Treatment Outcome
D050034:Antidiuretic Agents; D003894:Deamino Arginine Vasopressin