Improvement of tardive dyskinesia following amisulpride treatment.
Tardive dyskinesia (TD) is a persistent, disturbing side effect of antipsychotic drug treatment. It is established that clozapine and other second generation agents cause less TD and may also improve pre-existing TD. We report a case of significant improvement of TD after the administration of amisulpride, a potential D(2)/D(3) antagonist that has atypical properties. The possible effect of fast dissociation of D(2) receptors is being discussed.
Department of Psychiatry, University Hospital of Ioannina, Panepistimiou Avenue, Ioannina, Greece. vperitogiannis@yahoo.com
Vaios
V
Peritogiannis
Sofia
S
Tsouli
Spiros
S
Zafiris
Dimitrios
D
Pappas
Venetsanos
V
Mavreas
D000077582:Amisulpride; D014150:Antipsychotic Agents / Q000009:adverse effects*; D020820:Dyskinesias / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012563:Schizophrenia, Paranoid / Q000188:drug therapy; D013469:Sulpiride / Q000009:adverse effects / Q000031:analogs & derivatives*
D014150:Antipsychotic Agents; D013469:Sulpiride; D000077582:Amisulpride