Test accuracy and prognostic validity of multiple auditory steady state responses for targeted hearing screening.
The test accuracy and prognostic validity of Multiple Auditory Steady State Responses (MSSR) and click Auditory Brainstem Responses (cABR) was compared within the context of a targeted screening protocol. A sample of 508 high-risk babies was first screened using cABR and MSSR (500 and 2000 Hz). All children (failed/ pass) were called back at three to four years of age to determine their hearing status (pure-tone audiometry). Although both methods showed an equally good test performance in the first screen (sensitivity: 100% and specificity: 92-95%), the MSSR may have some potential advantage to identify low-frequency hearing loss. Furthermore, the confirmatory audiometry with MSSR predicted the child hearing status more accurately than the cABR. In conclusion, the MSSR can provide valuable information for the diagnosis and management of infants earlier detected by a screening protocol and further developed might be also useful as a screening test.
Cuban Neuroscience Center, La Habana, Cuba. guille@cneuro.edu.cu
Guillermo
G
Savio
Maria Cecilia
MC
Perez-Abalo
Jose
J
Gaya
Odelaysis
O
Hernandez
Eleina
E
Mijares
D000161:Acoustic Stimulation / Q000379:methods*; D001300:Audiometry, Evoked Response / Q000379:methods / Q000592:standards*; D002138:Calibration; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening / Q000379:methods* / Q000592:standards; D011379:Prognosis; D011930:Reaction Time; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013637:Tape Recording