Uncommon, exceptional and atypical: a case of frontal lobe epilepsy due to cortical dysplasia.
We report a case of frontal lobe epilepsy due to focal cortical dysplasia that included three independent unusual features. The patient, a 45-year-old, right-handed woman, had her first seizure at age 29, well into adulthood. Seizures had been easily controlled with medication for 15 years, then without provocation they became medically intractable during a single, identifiable day. Resection of the dysplastic tissue in the posterior dorsolateral right frontal cortex rendered the patient seizure-free, but produced a significant, non-fluent, Broca type, crossed aphasia. In addition, the seizure semiology was striking and remarkable, a common finding in frontal lobe epilepsy. [Published with video sequences].
Department of Neurology, New York University School of Medicine, USA. arthur.grant@med.nyu.edu
Arthur C
AC
Grant
Richard B
RB
Kim
D001037:Aphasia / Q000209:etiology; D002540:Cerebral Cortex / Q000002:abnormalities*; D017034:Epilepsy, Frontal Lobe / Q000209:etiology* / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D014741:Video Recording