Impaired motor control in patients with benign focal epilepsy of childhood.
Upper extremity motor function was quantitatively assessed in 6 children (age 7-11 years) treated with antiepileptic drugs for benign focal epilepsies of childhood and compared with that of 30 age-matched normal children. Both motor performance and adaptation to perturbing mechanical constraints imposed by a robotic device were significantly impaired in children with benign focal epilepsies of childhood. Our findings thus question whether certain "benign" epilepsies are truly benign and whether pharmacologic treatment might contribute to motor impairment.
Maalouf
Marwan
M
Department of Neurology, University of California at Irvine College of Medicine, USA. Marwan.Maalouf@chw.edu
Takahashi
Craig D
CD
Reinkensmeyer
David J
DJ
Cooper
Dan M
DM
Rho
Jong M
JM
D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D004569:Electroencephalography / Q000187:drug effects; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D009949:Orientation; D011596:Psychomotor Disorders / Q000139:chemically induced / Q000175:diagnosis*
D000927:Anticonvulsants