[Neuromodulatory effects of bromazepam when individuals were exposed to a motor learning task: quantitative electroencephalography (qEEG)].
The sedative effects of bromazepam on cognitive and performance have been widely investigated. A number of different approaches have assessed the influence of bromazepam when individuals are engaged to a motor task. In this context, the present study aimed to investigate electrophysiological changes when individuals were exposed to a typewriting task after taking 6 mg of bromazepam. qEEG data were simultaneously recorded during the task. In particular, relative power in delta band (0.5-3.5 Hz) was analyzed. Time of execution and errors during the task were registered as behavioral variables. The experimental group, bromazepam 6 mg, showed a better motor performance and higher relative power than control individuals (placebo). These results suggest that the use of bromazepam reduces anxiety levels as expected and thus, produces an increment in motor performance.
Salles
José Inácio
JI
Laboratório de Mapeamento Cerebral e Integração Sensório-Motora, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Bastos
Victor Hugo
VH
Cunha
Marlo
M
Machado
Dionis
D
Cagy
Maurício
M
Furtado
Vernon
V
Basile
Luis Fernando
LF
Piedade
Roberto
R
Ribeiro
Pedro
P
D000513:Alpha Rhythm; D000704:Analysis of Variance; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001960:Bromazepam / Q000494:pharmacology*; D016022:Case-Control Studies; D004594:Electrophysiology; D006801:Humans; D007858:Learning / Q000187:drug effects*; D009048:Motor Skills / Q000187:drug effects* / Q000502:physiology; D011597:Psychomotor Performance / Q000187:drug effects* / Q000502:physiology
D014151:Anti-Anxiety Agents; D001960:Bromazepam