Osteomyelitis as a late complication of Bacille Calmette-Guérin vaccination.
Bacille Calmette-Guérin (BCG) osteomyelitis is a very rare complication of BCG vaccination. We report a 14-month-old boy who received BCG vaccination at birth. He developed pain and swelling in his left calf at 11 months of age. BCG osteomyelitis was diagnosed in right femur and left tibia. He had no evidence of immunodeficiency. After antituberculous therapy and surgical treatment, the bone lesions disappeared and he was discharged from hospital without any sequela during 11 months of follow-up.
Khotaei
Ghamar Taj
GT
Department of Infectious Disease, Children Medical Center, Tehran University of Medical Sciences, Tehran, IR Iran. khotaei@sina.tums.ac.ir
Sedighipour
Leyla
L
Fattahi
Fatemeh
F
Pourpak
Zahra
Z
D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D005269:Femur / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging
D000995:Antitubercular Agents; D001500:BCG Vaccine