Hypocholesterolaemic effects of milk-kefir and soyamilk-kefir in cholesterol-fed hamsters.
This study aimed to evaluate the hypocholesterolaemic property of milk-kefir and soyamilk-kefir. Male hamsters were fed on a cholesterol-free or cholesterol-enriched diet containing 10 % skimmed milk, milk-kefir, soyamilk or soyamilk-kefir for a period of 8 weeks. The soyamilk, milk-kefir and soyamilk-kefir diets all tended towards a lowering of serum triacylglycerol and total cholesterol concentrations, and a reduction of cholesterol accumulation in the liver, the decrease in serum cholesterol concentration being mainly in the non-HDL fraction. The soyamilk-kefir diet led to a significant increase in the faecal excretion of neutral sterols and bile acids compared with the other two diets. The soyamilk-kefir diet also elicited a significant decrease in the serum ratio of non-HDL-cholesterol to HDL-cholesterol, compared with the control, than was the case for the other diets. These findings demonstrate that soyamilk-kefir may be considered to be among the more promising food components in terms of preventing CVD through its hypocholesterolaemic action.
Liu
Je-Ruei
JR
Department of Biotechnology, National Formosa University, Taiwan. jrliu@sunws.nfu.edu.tw
Wang
Sheng-Yao
SY
Chen
Ming-Ju
MJ
Chen
Hsiao-Ling
HL
Yueh
Pei-Ying
PY
Lin
Chin-Wen
CW
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D006224:Cricetinae; D043302:Cultured Milk Products; D004032:Diet; D004435:Eating; D005243:Feces / Q000737:chemistry; D006937:Hypercholesterolemia / Q000473:pathology / Q000517:prevention & control*; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D009929:Organ Size; D041942:Soy Milk; D013261:Sterols / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism; D015430:Weight Gain
D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D008055:Lipids; D013261:Sterols; D014280:Triglycerides; D002784:Cholesterol