title: Multiphasic disseminated encephalomyelitis, systemic lupus erythematosus and antiphospholipid syndrome.
abstract: We report a case of multiphasic disseminated encephalomyelitis (MDEM) associated with systemic lupus erythematosus (SLE) and antiphospholipid syndrome. The initial presentation was suggestive of multiple sclerosis. Further clinical attacks, MRI imaging, and CSF findings led to a diagnosis of disseminated encephalomyelitis (DEM). Multiple episodes of neurological dysfunction, which differed in clinical presentation, further categorized the diagnosis as multiphasic DEM. The co-occurrence SLE and antiphospholipid syndrome is unusual and provided an additional diagnostic challenge.
authors.affiliation: Maxine Mesinger MS Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA. lob828828@yahoo.com.mx
authors.forename: Laura
authors.initials: L
authors.lastname: Ordonez
authors.forename: Eli
authors.initials: E
authors.lastname: Skromne
authors.forename: Daniel
authors.initials: D
authors.lastname: Ontaneda
authors.forename: Victor M
authors.initials: VM
authors.lastname: Rivera
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*