title: Study of severe and rare complications of transarterial chemoembolization (TACE) for liver cancer.
abstract: OBJECTIVE
  To study severe and rare complications of transarterial chemoembolization (TACE) for liver cancer.
  
  
  METHODS
  Clinical records of severe and rare complications following TACE in 1348 cases of liver cancer from January 1997 to February 2004 were studied retrospectively.
  
  
  RESULTS
  A total of 2012 TACE procedures were performed for 1348 patients. There were 3 cases of spontaneous rupture of liver cancer, 1 case of perforation of duodenum, 3 cases of liver abscess (1 of them was associated with sepsis), 1 case of pulmonary embolism, 1 case of spasm of the hepatic artery, 40 cases of hepatic artery occlusion, 3 cases of femoral nerve injury, 1 case of bilioma and 1 case of acute renal failure.
  
  
  CONCLUSIONS
  Although the severe complications of TACE are rare, the procedure should be done cautiously including super selection of hepatic artery, slow infusion of lipiodol, careful postoperative observations and early detection and management of complications.
authors.affiliation: Liver Cancer Institute, Zhongshan Hospital, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, PR China.
authors.forename: Jinglin
authors.initials: J
authors.lastname: Xia
authors.forename: Zhenggang
authors.initials: Z
authors.lastname: Ren
authors.forename: Shenglong
authors.initials: S
authors.lastname: Ye
authors.forename: Dilip
authors.initials: D
authors.lastname: Sharma
authors.forename: Zhiying
authors.initials: Z
authors.lastname: Lin
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Gan
authors.forename: Yi
authors.initials: Y
authors.lastname: Chen
authors.forename: Ninglin
authors.initials: N
authors.lastname: Ge
authors.forename: Zengchen
authors.initials: Z
authors.lastname: Ma
authors.forename: Zhiquan
authors.initials: Z
authors.lastname: Wu
authors.forename: Jia
authors.initials: J
authors.lastname: Fan
authors.forename: Lunxiu
authors.initials: L
authors.lastname: Qin
authors.forename: Xinda
authors.initials: X
authors.lastname: Zhou
authors.forename: Zhaoyou
authors.initials: Z
authors.lastname: Tang
authors.forename: Binghui
authors.initials: B
authors.lastname: Yang
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage; D008099:Liver / Q000098:blood supply; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D012189:Retrospective Studies
chemical_list: D000970:Antineoplastic Agents; D016685:Mitomycin; D007459:Iodized Oil; D002945:Cisplatin; D005472:Fluorouracil