title: Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node.
abstract: A gradually enlarging axillary mass in a 79-year-old man was excised. The specimen was processed for light microscopy, immunohistochemical studies, and electron microscopy; gene rearrangement studies were also performed. A diagnosis of an interdigitating dendritic cell tumor of the lymph node and a B-cell small lymphocytic lymphoma occurring in the same anatomic location was made. We found that although rare cases of interdigitating dendritic cell tumor with an associated secondary malignancy have been described in the literature, to our knowledge, this is the first report of interdigitating dendritic cell tumor and synchronous neoplasm diagnosed at the same site. A possible relationship between the 2 disorders is also discussed.
authors.affiliation: Institutes of Anatomic Pathology and Histopathology, University of Sassari, Sassari, Italy. cossu@uniss.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Cossu
authors.forename: Angelo
authors.initials: A
authors.lastname: Deiana
authors.forename: Amelia
authors.initials: A
authors.lastname: Lissia
authors.forename: Maria Filomena
authors.initials: MF
authors.lastname: Dedola
authors.forename: Lucia
authors.initials: L
authors.lastname: Cocco
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palmieri
authors.forename: Francesco
authors.initials: F
authors.lastname: Tanda
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003713:Dendritic Cells / Q000737:chemistry / Q000473:pathology*; D017809:Fatal Outcome; D015326:Gene Rearrangement, B-Lymphocyte, Heavy Chain / Q000235:genetics; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D008198:Lymph Nodes / Q000737:chemistry / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology*; D012509:Sarcoma / Q000737:chemistry / Q000235:genetics / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D007143:Immunoglobulin Heavy Chains