title: An unusual aneurysm of the main pulmonary artery presenting as acute coronary syndrome.
abstract: A 70-year old man presented with retrosternal chest pain. His electrocardiogram showed nonspecific T wave changes. Cardiac-specific troponin I (cTnI) was elevated. His condition was managed as acute coronary syndrome, following which he had two minor episodes of hemoptysis. A CT pulmonary angiogram showed no evidence of pulmonary embolism, but a large mass lesion was seen in the mediastinum. Echocardiography and cardiac MRI demonstrated a large solid mass, arising from the right ventricular outflow tract and causing compression of the main pulmonary artery (MPA). The differential diagnosis included pericardial and myocardial tumors and clotted aneurysm of the MPA. At surgery, a clotted aneurysmal sac was identified originating from the MPA and the defect was healed. Aneurysms of the MPA are rare. They most commonly present with dyspnea and chest pain. Compression of surrounding structures produces protean manifestations. A high index of suspicion coupled with imaging modalities establishes the diagnosis. Blunt trauma to the chest, at the time of an accident 4 years previously, may explain this aneurysm. The patient's presentation with chest pain was probably due to compression and/or stretching of surrounding structures. Coronary artery compression simulating acute coronary syndrome has been documented in the literature. The rise in cTnI may have been due to right ventricular strain, as a result of right ventricular outflow obstruction by the aneurysm. This has not been reported previously in the literature. The saccular morphology and narrow neck of the aneurysm predisposed to stagnation leading to clotting of the lumen and healing of the tear, which caused the diagnostic difficulty.
authors.affiliation: Department of Medicine, King Khalid National Guard Hospital, King Abdul-Aziz Medical City, P.O. Box 9515, Jeddah 21423, Kingdom of Saudi Arabia. omahmed56@yahoo.com
authors.forename: Mona A
authors.initials: MA
authors.lastname: Kholeif
authors.forename: Mohamed El
authors.initials: ME
authors.lastname: Tahir
authors.forename: Yasser A
authors.initials: YA
authors.lastname: Kholeif
authors.forename: Ahmed El
authors.initials: AE
authors.lastname: Watidy
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000150:complications / Q000175:diagnosis*; D002637:Chest Pain / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis; D011651:Pulmonary Artery; D014057:Tomography, X-Ray Computed