title: Effect of supplementation of Agaricus mushroom meal extracts on enzyme activities in peripheral leukocytes of calves.
abstract: To investigate the effect of Agaricus mushroom meal on the energy metabolism in animal tissues; plasma glucose, triglyceride, cholesterol and immunoreactive insulin (IRI) concentrations and activities of enzymes related to energy metabolism in plasma and peripheral leukocytes were measured in Japanese Black WagyuxHolstein F1 calves supplemented with Agaricus blazei Murill (A. blazei) extract in milk-replacer at the dose of 60g/head/day for 4 weeks. Activities of malate dehydrogenase and aspartate aminotransferase in cytosol and glutamate dehydrogenase in mitochondria, and the malate dehydrogenase/lactate dehydrogenase ratio in cytosol in peripheral leukocytes of calves with A. blazei were significantly higher than those in control calves without A. blazei. It was concluded that supplementation of Agaricus mushroom meal extract was effective in activation of enzymes related to energy metabolism in peripheral leukocytes of calves.
authors.affiliation: Division of Animal Nutrition, Department of Animal Science, Nippon Veterinary and Animals Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan. knob3@nvau.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Kimura
authors.forename: E
authors.initials: E
authors.lastname: Fujino
authors.forename: S
authors.initials: S
authors.lastname: Urabe
authors.forename: H
authors.initials: H
authors.lastname: Mizutani
authors.forename: T
authors.initials: T
authors.lastname: Sako
authors.forename: S
authors.initials: S
authors.lastname: Imai
authors.forename: Y
authors.initials: Y
authors.lastname: Toyoda
authors.forename: T
authors.initials: T
authors.lastname: Arai
mesh_terms: D000364:Agaricus; D000821:Animal Feed / Q000032:analysis*; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle; D004032:Diet / Q000662:veterinary*; D019587:Dietary Supplements; D005260:Female; D007962:Leukocytes / Q000187:drug effects* / Q000201:enzymology*; D008297:Male