title: Organelles on the move: insights from yeast vacuole inheritance.
abstract: Organelle inheritance is one of several processes that occur during cell division. Recent studies on yeast vacuole inheritance have indicated rules that probably apply to most organelle-inheritance pathways. They have uncovered a molecular mechanism for membrane-cargo transport that is partially conserved from yeast to humans. They have also shown that the transport complex, which is composed of a molecular motor and its receptor, regulates the destination and timing of vacuole movement and might coordinate organelle movement with several other organelle functions.
authors.affiliation: Department of Cell and Developmental Biology and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA. lweisman@umich.edu
authors.forename: Lois S
authors.initials: LS
authors.lastname: Weisman
mesh_terms: D002453:Cell Cycle / Q000502:physiology*; D008954:Models, Biological; D008958:Models, Molecular; D020409:Molecular Motor Proteins / Q000502:physiology; D015388:Organelles / Q000235:genetics / Q000502:physiology*; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D014617:Vacuoles / Q000235:genetics / Q000502:physiology*
chemical_list: D020409:Molecular Motor Proteins; D029701:Saccharomyces cerevisiae Proteins