Afzeliixanthones A and B, two new prenylated xanthones from Garcinia afzelii ENGL. (Guttiferae).
Two new prenylated xanthones, afzeliixanthones A (1) and B (2), together with three known xanthones (3-5) and two phytosterols, beta-sitosterol and stigmasterol, were isolated from the CH2Cl2/MeOH (1:1) extract of the stem bark of Garcinia afzelii ENGL. collected in the South West Province of Cameroon. Structures were mainly established using one and two-dimensional NMR and mass spectroscopies. The antioxidant activities of the crude extracts as well as the new compounds (1) and (2) were evaluated.
Kamdem Waffo
Alain François
AF
Department of Chemistry, Faculty of Science, University of Douala, Cameroon. akamdemfr@yahoo.fr
Mulholland
Dulcie
D
Wansi
Jean Duplex
JD
Mbaze
Luc Meva'a
LM
Powo
Robert
R
Mpondo
Theophile Ngando
TN
Fomum
Zacharias Tanee
ZT
König
Wilfried
W
Nkengfack
Augustin Ephrem
AE
D000975:Antioxidants / Q000494:pharmacology*; D029760:Garcinia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013265:Stigmasterol / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000975:Antioxidants; D010936:Plant Extracts; D012855:Sitosterols; D044004:Xanthones; C511005:afzeliixanthone A; C511006:afzeliixanthone B; C025473:gamma-sitosterol; D013265:Stigmasterol