title: [Differentiated thyroid cancer--peculiar morphological and clinical forms].
abstract: The most common clinical presentation of differentiated thyroid cancer (DTC), consisting of papillary and follicular adenocarcinoma (with their histological variants), is the solitary thyroid nodule. A review of the literature is performed in order to describe particular forms of DTC, in terms of incidence, diagnosis and treatment: occult carcinoma, carcinoma on aberrant thyroid tissue, "functional" thyroid carcinoma and familial non-medullary carcinoma. A particular interest is shown to the coexistence of malignancy with benign thyroid diseases, such as goiter, hyperthyroidism and Hashimoto's thyroiditis, as well as parathyroid adenoma. In conclusion, the authors emphasize that the association of carcinoma with benign thyroid conditions is not rare and it substantiate an aggressive approach in regard to diagnosis and treatment, increasing the indication for surgery and, moreover, for total thyroidectomy.
authors.affiliation: Clinica a III-a Chirurgie, Facultatea de Medicină, Universitatea de Medicină si Farmacie "Gr. T. Popa", Iaşi.
authors.forename: R
authors.initials: R
authors.lastname: Dănilă
authors.forename: Lidia
authors.initials: L
authors.lastname: Andriescu
authors.forename: Cristina
authors.initials: C
authors.lastname: Dăscălescu
authors.forename: L P
authors.initials: LP
authors.lastname: Lefter
authors.forename: Ramona
authors.initials: R
authors.lastname: Popovici
authors.forename: B
authors.initials: B
authors.lastname: Găluşcă
authors.forename: Carmen
authors.initials: C
authors.lastname: Vulpoi
authors.forename: Cristina
authors.initials: C
authors.lastname: Ungureanu
authors.forename: Voichiţa
authors.initials: V
authors.lastname: Mogoş
authors.forename: Cr
authors.initials: C
authors.lastname: Dragomir
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000231:Adenocarcinoma, Papillary / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D013959:Thyroid Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013964:Thyroid Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D016606:Thyroid Nodule / Q000150:complications / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy