A convenient gram-scale synthesis of uridine diphospho(13C6)glucose.
A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-1-phosphate and UMP-morpholidate. The uridine diphospho(13C6)glucose was used in the structural identification of (1-->3)-beta-D-glucan from Lolium multiflorum.
Dinev
Zoran
Z
School of Chemistry, University of Melbourne, Parkville, Victoria 3010, Australia.
Wardak
Ahmad Z
AZ
Brownlee
Robert T C
RT
Williams
Spencer J
SJ
D002247:Carbon Isotopes; D005958:Glucosephosphates / Q000737:chemistry; D007553:Isotope Labeling / Q000379:methods; D008129:Lolium / Q000737:chemistry; D014532:Uridine Diphosphate Glucose / Q000138:chemical synthesis*; D047071:beta-Glucans / Q000737:chemistry
D002247:Carbon Isotopes; D005958:Glucosephosphates; D047071:beta-Glucans; D014532:Uridine Diphosphate Glucose