[Lymphadenopathy and constitutional symptoms. Progress of a low-grade follicular lymphoma?].
Atypical presentation of Churg-Strauss syndrome includes lymph-node and parenchymatous organ involvement which mimics the clinical presentation of lymphoproliferative disorders.A 54-year old man with a history of a low-grade follicular lymphoma presented with rapidly growing abdominal lymph-nodes and hepatic, renal and pulmonary infiltrations. CT guided biopsies to verify either lymphoma or infections showed eosinophilic, necrotizing, granulomatous vasculitis leading to the diagnosis of atypical Churg-Strauss syndrome. Within a few days of cyclophosphamide and prednisone treatment the clinical presentation improved and imaging studies detected regression of all manifestations during follow-up.
Stemmler
H J
HJ
Medizinische Klinik III, Klinikum Grosshadern der LMU München. joachim.stemmler@med.uni-muenchen.de
Hoelzl
M
M
Moosmann
N
N
Becker
C
C
Lennertz
A
A
Babaryka
G
G
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D015267:Churg-Strauss Syndrome / Q000175:diagnosis*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology*; D008224:Lymphoma, Follicular / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed