The engineering of endovascular stent technology: a review.
The evolution of minimally invasive endovascular technology has initiated a significant paradigm shift in the treatment of vascular disease. A fundamental understanding of the science and engineering behind the technology of endovascular stents is a key to their appropriate implementation in practice. Furthermore, the rapid influx of new devices into the field requires practitioners to make their decisions on a foundation of the relative strengths and weaknesses of the various products. Although the principles of their use are not complex, the device design can have a profound effect on the device's functionality. Shape, thickness, coating, material selection, and imaging are just a few of the factors to consider in stent design. Subtle differences may have profound results. This review is designed to provide the reader with an overview of fundamental concepts that will aide the assessment of new technology.
Whittaker
David R
DR
Dartmouth-Hitchcock Medical Center, Section of Vascular Surgery, Lebanon, NH, USA. Dr.whittaker@att.net
Fillinger
Mark F
MF
D001672:Biocompatible Materials; D001808:Blood Vessels / Q000187:drug effects / Q000473:pathology; D016503:Drug Delivery Systems / Q000295:instrumentation*; D006801:Humans; D006965:Hyperplasia; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation; D017239:Paclitaxel / Q000008:administration & dosage*; D011474:Prosthesis Design; D016032:Randomized Controlled Trials as Topic; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D014656:Vascular Surgical Procedures / Q000295:instrumentation*
D001672:Biocompatible Materials; D017239:Paclitaxel; D020123:Sirolimus