Regulation of maternal metabolism by pituitary and placental hormones: roles in fetal development and metabolic programming.
This review outlines the regulation of maternal metabolism by hormones, cytokines and growth factors, highlighting recent studies that implicate disordered somatolactogen signalling in the pathogenesis of perinatal growth failure and the development of the metabolic syndrome.
Freemark
M
M
Division of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC 27710, USA. freem001@mc.duke.edu
D000818:Animals; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D013006:Growth Hormone / Q000502:physiology; D006801:Humans; D010907:Pituitary Hormones / Q000502:physiology*; D010926:Placental Hormones / Q000502:physiology*; D010928:Placental Lactogen / Q000502:physiology; D011247:Pregnancy / Q000378:metabolism*; D011388:Prolactin / Q000502:physiology
C064980:GH2 protein, human; D010907:Pituitary Hormones; D010926:Placental Hormones; D011388:Prolactin; D013006:Growth Hormone; D010928:Placental Lactogen