title: Cardiolipin in hydrogenosomes: evidence of symbiotic origin.
abstract: Hydrogenosomes are found in organisms that lack typical mitochondria. Cardiolipin is a phospholipid located exclusively in bacterial membranes and the inner membrane of mitochondria. Here we show, by cell fractionation, thin-layer chromatography, high-pressure liquid chromatography, and matrix-assisted laser desorption ionization-time of flight mass spectrometry that hydrogenosomes of Tritrichomonas foetus, a cattle vaginal parasite, contain cardiolipin, which is strong evidence for its endosymbiotic origin.
authors.affiliation: Laboratorio de Ultraestrutura Celular, Univeridade Santa Ursula, Rio de Janeiro, Brazil.
authors.forename: Ivone
authors.initials: I
authors.lastname: de Andrade Rosa
authors.forename: Marcelo
authors.initials: M
authors.lastname: Einicker-Lamas
authors.forename: Róbson
authors.initials: R
authors.lastname: Roney Bernardo
authors.forename: Lucia Mendonça
authors.initials: LM
authors.lastname: Previatto
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Mohana-Borges
authors.forename: José Andrés
authors.initials: JA
authors.lastname: Morgado-Díaz
authors.forename: Marlene
authors.initials: M
authors.lastname: Benchimol
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002308:Cardiolipins / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D008928:Mitochondria / Q000737:chemistry / Q000378:metabolism; D015388:Organelles / Q000737:chemistry* / Q000378:metabolism; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013559:Symbiosis; D014244:Trichomonas / Q000737:chemistry*
chemical_list: D002308:Cardiolipins