[Disseminated tuberculosis and profound thrombopenia].
Thrombocytopenia within the context of disseminated tuberculosis can lead to complications requiring rapid treatment. Although the origin is generally central, thrombocytopenia can arise from an immune disorder. We hereby report a case of disseminated tuberculosis associated with thrombocytopenia, which required, in addition to antituberculosis therapy initiated before bacteriological proof, corticosteroid treatment and multiple platelet transfusions. The discovery of anti-platelet antibodies along with the success of immunomodulator therapy confirmed the auto-immune origin of this thrombocytopenia.
Leroux
P
P
Centre de Diagnostic, Hôtel-Dieu, AP-HP, 4 Place du Parvis Notre-Dame, 75181 Paris cedex 04.
de Champs Léger
H
H
Le Vezouet
C-A
CA
Ilie
D
D
Regnier
C
C
Motlagh
P
P
Soulie
J-H
JH
Perles
C
C
Gilbert
J-C
JC
Safar
M
M
Blacher
J
J
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D013902:Radiography, Thoracic; D013921:Thrombocytopenia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014376:Tuberculosis / Q000097:blood* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000995:Antitubercular Agents