"Achiral" benzophenone ligand for highly enantioselective Ru catalysts in ketone hydrogenation.
[reaction: see text] The chirality of an "achiral" benzophenone-based complex can be controlled. The benzophenone-based complex thus controlled affords high enantioselectivity in the catalytic asymmetric ketone hydrogenation (up to 99% ee, >99% yield).
Mikami
Koichi
K
Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152-8552, Japan. kmikami@o.cc.titech.ac.jp
Wakabayashi
Kazuki
K
Aikawa
Kohsuke
K