[Experimental modeling of the blood vessels magnetic embolization].
The embolization of blood vessels is used on a large scale: the method is applied in different diseases, in the ablation of organs, but especially in tumor necrosis. The embolization can be also magnetic, if the embolus is obtained through the deposit in the vessel of magnetic nano or microparticles in the presence of an external magnetic field. The objective of our study was the modeling of the magnetic embolization using amorphous magnetic microspheres that have strong magnetic properties and are biocompatible. Experimental tests were made in order to observe the building of the magnetic embolus inside a thin spiral tube and to determine the influence of some parameters on the efficiency of occlusions: the dimensions of magnetic microspheres (1-300 mm), the debit of the liquid (4.66 - 16.5 ml/min), the viscosity of the carrier liquid (1.007 - 7.34 cSt), the direction and the intensity of the external magnetic field (340 - 600 Gs), the shape of the tube and the linear length of the deposit (5 - 50 mm). Under pre-established experimental conditions the efficiencies of occlusions were between 67% and 100%.
Iacob
Gh
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Disciplina de Electrotehnică, Facultatea de Bioinginerie Medicală, Universitatea de Medicină si Farmacie "Gr. T. Popa", Iaşi.
Ciochină
Al D
AD
Bredeţean
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O
D001808:Blood Vessels; D004621:Embolization, Therapeutic; D004867:Equipment Design; D006801:Humans; D008280:Magnetics; D008863:Microspheres; D009369:Neoplasms / Q000628:therapy