Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasis.
Sodium stibogluconate (Pentostam(R); GlaxoSmithKline) is a pentavalent antimonial compound used in the treatment of leishmaniasis, which has an association with reactivation of varicella zoster virus (VZV). We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate.
Hartzell
Joshua D
JD
Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA. Joshua.hartzell@na.amedd.army.mil
Aronson
Naomi E
NE
Nagaraja
Sudhir
S
Whitman
Tim
T
Hawkes
Clifton A
CA
Wortmann
Glenn
G
D000328:Adult; D000818:Animals; D000967:Antimony Sodium Gluconate / Q000009:adverse effects*; D000981:Antiprotozoal Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D020804:Encephalitis, Varicella Zoster / Q000209:etiology*; D006562:Herpes Zoster; D006801:Humans; D018320:Leishmania major / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D017193:Skin Diseases, Viral / Q000209:etiology
D000981:Antiprotozoal Agents; D000967:Antimony Sodium Gluconate