[Polymorphism of vitamin D receptor gene Fok I in Mongolian population of China].
OBJECTIVE
To investigate the polymorphism distribution of vitamin D receptor (VDR) gene Fok I in Mongolian population of China.


METHODS
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used to analyze three genotypes FF, Ff and ff in the start codon of VDR gene (Fok I) in unrelated normal healthy Mongolian individuals of China.


RESULTS
In the population, we obtained the allelic frequencies of 57% and 43% for (F) and (f) allele and the percentage of genotypes FF, Ff and ff to be 31%, 52%, and 17% respectively.


CONCLUSIONS
The polymorphism frequency and distribution of this VDR gene Fok I in Mongolian population of China exhibit its own characteristics.
Xing
Shao-ji
SJ
Department of Biochemistry and Molecular Biology, Baotou Medical College, Baotou, Inner Mongolia, 014010 P.R.China. xingshaojihao@yahoo.com.cn
Zhou
Li-she
LS
Xu
Xiu-ju
XJ
D000328:Adult; D000368:Aged; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D011153:Population; D044382:Population Groups / Q000235:genetics; D018167:Receptors, Calcitriol / Q000235:genetics*
D018167:Receptors, Calcitriol