title: Embryonal tumor with abundant neuropil and true rosettes. A new entity or only variations of a parent neoplasms (PNETs)? This is the dilemma.
abstract: A rare embryonal brain tumor has been diagnosed in a 4-year-old boy. The mass, located at the pons and mesencephalon, has been histologically classified as an embryonal tumor containing abundant neuropil and true rosettes. After surgical complete removal of the neoplasia, the child received intensive combined chemotherapy and radiotherapy. He is alive and free of disease at 34 months from surgery. Difficulties in histological definition, possible suggestions for treatment proposals are discussed.
authors.affiliation: Division of Hematology/Oncology, Department of Pediatrics, Catania University Hospital, Catania, Sicily, Italy. mlaspina@unict.it
authors.forename: M
authors.initials: M
authors.lastname: La Spina
authors.forename: S
authors.initials: S
authors.lastname: Pizzolitto
authors.forename: M
authors.initials: M
authors.lastname: Skrap
authors.forename: A
authors.initials: A
authors.lastname: Nocerino
authors.forename: G
authors.initials: G
authors.lastname: Russo
authors.forename: A
authors.initials: A
authors.lastname: Di Cataldo
authors.forename: G
authors.initials: G
authors.lastname: Perilongo
mesh_terms: D001932:Brain Neoplasms / Q000145:classification / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008636:Mesencephalon / Q000473:pathology; D018242:Neuroectodermal Tumors, Primitive / Q000145:classification / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D019581:Neuropil / Q000473:pathology*; D011149:Pons / Q000473:pathology; D016896:Treatment Outcome