title: [A case of scirrhous gastric cancer responding to TS-1/CDDP neoadjuvant chemotherapy].
abstract: A 72-year-old female with scirrhous-type advanced gastric cancer was treated with TS-1/CDDP as neoadjuvant chemotherapy. TS-1 (80 mg/m(2)/day) was orally administered for 3 weeks and CDDP (60 mg/m(2)) was administered by intravenous drip on day 8. Partial response (PR) was obtained after the first course, and total gastrectomy was performed. The histological diagnosis revealed complete disappearance of cancer cells in the stomach and a few regional lymph node metastases (3/67). The patient has now been in good health without a recurrence for 1 year and 9 months after surgery.
authors.affiliation: Dept. of Surgery, Urasoe General Hospital.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kameyama
authors.forename: Ryota
authors.initials: R
authors.lastname: Murayama
authors.forename: Keiko
authors.initials: K
authors.lastname: Miyazato
authors.forename: Kaname
authors.initials: K
authors.lastname: Kurashita
authors.forename: Tomonari
authors.initials: T
authors.lastname: Ishimine
authors.forename: Yoshitetsu
authors.initials: Y
authors.lastname: Nagamine
authors.forename: Fumiko
authors.initials: F
authors.lastname: Kohakura
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Shinzato
authors.forename: Kou
authors.initials: K
authors.lastname: Tomimori
authors.forename: Yukino
authors.initials: Y
authors.lastname: Kugai
authors.forename: Hisataka
authors.initials: H
authors.lastname: Uchima
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D020360:Neoadjuvant Therapy; D010094:Oxonic Acid / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin