title: Actinic keratosis and capecitabine therapy.
abstract: Topical application of 5-fluorouracil (5-FU) is one of the most effective clinical strategies available to treat actinic keratosis (AK). During treatment, an apparent toxic skin reaction occurs before dermal quiescence ensues. We report a case of a typical flare of AK in a woman treated with capecitabine for advanced breast cancer.
authors.affiliation: Department of Medicine, Section of Hematology/Oncology, West Virginia University, Morgantown, USA. ghiga@hsc.wvu.edu
authors.forename: Gerald M
authors.initials: GM
authors.lastname: Higa
authors.forename: Rodney F
authors.initials: RF
authors.lastname: Kovach
authors.forename: Jame
authors.initials: J
authors.lastname: Abraham
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D000069287:Capecitabine; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives; D006801:Humans; D007642:Keratosis / Q000139:chemically induced*
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil