title: Seroprevalence and molecular epidemiology of human T-Cell leukemia virus type 1 (HTLV-1) and HTLV-2 in blood donors from Dakar, Senegal.
abstract: In 2002, human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 seroprevalence was 0.16% (8/4,900) in blood donors from Dakar, Senegal. Most of the positive donors originated from the country's southern region. Seven donors were infected by HTLV-1 (of cosmopolitan subtype), and one was infected by HTLV-2. These data highlight the problem of transfusion safety in this area where HTLV-1-associated lymphoproliferative and neurological diseases are endemic.
authors.affiliation: Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Département Ecosytèmes et Epidémiologie des Maladies Infectieuses, Batiment Lwoff, Institut Pasteur, 25-28 Rue du Dr. Roux, 75724 Paris, Cedex 15, France.
authors.forename: Saliou
authors.initials: S
authors.lastname: Diop
authors.forename: Sara
authors.initials: S
authors.lastname: Calattini
authors.forename: Julienne
authors.initials: J
authors.lastname: Abah-Dakou
authors.forename: Doudou
authors.initials: D
authors.lastname: Thiam
authors.forename: Lamine
authors.initials: L
authors.lastname: Diakhaté
authors.forename: Antoine
authors.initials: A
authors.lastname: Gessain
mesh_terms: D001782:Blood Donors; D015481:HTLV-I Antibodies / Q000032:analysis; D015486:HTLV-I Antigens / Q000032:analysis / Q000276:immunology; D015490:HTLV-I Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D015482:HTLV-II Antibodies / Q000032:analysis; D015487:HTLV-II Antigens / Q000032:analysis / Q000276:immunology; D015491:HTLV-II Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics* / Q000302:isolation & purification; D015367:Human T-lymphotropic virus 2 / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D011446:Prospective Studies; D012675:Senegal / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D015481:HTLV-I Antibodies; D015486:HTLV-I Antigens; D015482:HTLV-II Antibodies; D015487:HTLV-II Antigens