Potential roles of ROR-alpha in cardiovascular endocrinology.
Atherosclerosis is a chronic disease of the arteries whose development involves a local inflammatory response characterized by the activation of different cells such as macrophages, T-lymphocytes, smooth muscle cells (SMCs) and endothelial cells (ECs). This review will summarize recent evidence for a modulatory role of the nuclear receptor ROR-alpha in cardiovascular disease.
Laitinen
Saara
S
UR545 INSERM, Institut Pasteur de Lille, and Faculte de Pharmacie, Universite de Lille II, 1 rue du Pr Calmette 59019 Lille, France.
Staels
Bart
B