Possibility of a non-amino acid pathway in the biosynthesis of marine-derived oxazoles.
A novel avenue for oxazoles via Beckmann rearrangement of alpha-formyl ketoxime dimethyl acetals is described that indicates the possibility of a non-amino acid biosynthetic pathway in marine natural products.
Ichino
Takao
T
Department of Chemistry, Graduate School of Science, and Institute for Advanced Research, Nagoya University, Chikusa, Nagoya 464-8602, Japan. uemura@chem3.chem.nagoya-u.ac.jp
Arimoto
Hirokazu
H
Uemura
Daisuke
D
D000596:Amino Acids / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism; D056890:Eukaryota / Q000378:metabolism; D008387:Marine Toxins; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry* / Q000378:metabolism*
D000596:Amino Acids; D008387:Marine Toxins; D010080:Oxazoles; C059041:calyculin A