title: Investigation of a route to ibotenic acid analogues via a reduced pyroglutamate template.
abstract: Two alternative "ring switch" based syntheses have been shown to give access to the reduced protected homochiral analogues, 27, 28 and 36, of the CNS active compound ibotenic acid.
authors.affiliation: Department of Chemistry, University of Sussex, Falmer, Brighton, UK BN1 9QJ.
authors.forename: Omar
authors.initials: O
authors.lastname: Ahmed
authors.forename: Peter B
authors.initials: PB
authors.lastname: Hitchcock
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Young
mesh_terms: D018690:Excitatory Amino Acid Agonists / Q000138:chemical synthesis / Q000737:chemistry; D007051:Ibotenic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011761:Pyrrolidonecarboxylic Acid / Q000737:chemistry*
chemical_list: D018690:Excitatory Amino Acid Agonists; D007051:Ibotenic Acid; D011761:Pyrrolidonecarboxylic Acid