title: F-18 FDG PET demonstrates crossed cerebellar diaschisis 20 years after stroke.
abstract: Stroke produces an area of focal damage and distant areas of reduced blood blow and metabolism termed diaschisis. Tc-99m ECD and HMPAO brain SPECT have demonstrated crossed cerebellar diaschisis (CCD) in patients with cerebral cortical infarct. SPECT findings reflect abnormal cerebral blood flow. CCD as shown on F-18 FDG PET reflects abnormal reflects glucose metabolism. We present the case of a patient with laryngeal cancer who also had a stroke in the left cerebral hemisphere involving the territory of the middle cerebral artery 20 years ago. This patient underwent PET, including the head and neck. A current brain F-18 FDG PET exhibited hypometabolism in the contralateral cerebellum (CCD) as well as hypometabolism of the primary insult in the left cerebral hemisphere. These findings reflect partial impairment or diminished glucose metabolism in the primary insult to the cerebrum and contralateral cerebellum. In addition, this patient illustrates that on PET imaging, CCD could be demonstrated 20 years after a stroke.
authors.affiliation: Nuclear Medicine Service, Lexington VA Medical Center, KY, USA.
authors.forename: Wei-Jen
authors.initials: WJ
authors.lastname: Shih
authors.forename: Wen-Sheng
authors.initials: WS
authors.lastname: Huang
authors.forename: Primo P
authors.initials: PP
authors.lastname: Milan
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000209:etiology*; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D002531:Cerebellum / Q000098:blood supply / Q000000981:diagnostic imaging; D019788:Fluorodeoxyglucose F18; D006801:Humans; D033162:Incidental Findings; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging; D008137:Longitudinal Studies; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D020521:Stroke / Q000150:complications* / Q000000981:diagnostic imaging*; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18