Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development.
The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis.
Capestany
Cindy A
CA
Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610-0424, USA.
Kuboniwa
Masae
M
Jung
Il-Young
IY
Park
Yoonsuk
Y
Tribble
Gena D
GD
Lamont
Richard J
RJ
D001426:Bacterial Proteins / Q000502:physiology*; D018441:Biofilms / Q000254:growth & development*; D016966:Porphyromonas gingivalis / Q000502:physiology*
D001426:Bacterial Proteins; C069761:internalin protein, Bacteria