Direct, efficient, and inexpensive formation of alpha-hydroxyketones from olefins by hydrogen peroxide oxidation catalyzed by the 12-tungstophosphoric acid/cetylpyridinium chloride system.
The direct ketohydroxylation of a variety of 1-aryl-1-alkenes with H2O2, catalyzed by the inexpensive 12-tungstophosphoric acid/cetylpyridinium chloride system under very mild conditions, was achieved. Various acyloins were obtained in good yields and high regioselectivies.
Zhang
Yanfei
Y
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, Suzhou, 215123, China.
Shen
Zongxuan
Z
Tang
Jingting
J
Zhang
Yan
Y
Kong
Lichun
L
Zhang
Yawen
Y
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D002594:Cetylpyridinium / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D006900:Hydroxylation; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry / Q000191:economics; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010756:Phosphoric Acids / Q000737:chemistry*; D017973:Tungsten Compounds / Q000737:chemistry*
C519880:12-tungstophosphoric acid; D000475:Alkenes; D007659:Ketones; D010756:Phosphoric Acids; D017973:Tungsten Compounds; D006861:Hydrogen Peroxide; D002594:Cetylpyridinium