Human and mosquito infections by dengue viruses during and after epidemics in a dengue-endemic region of Colombia.
We conducted a study in a dengue-endemic area of Colombia to evaluate the dynamics of transmission of dengue viruses during and after epidemics. Information was simultaneously gathered about occurrence of infection in humans and mosquitoes every three months in four cities with endemic transmission. Viral isolation was confirmed in 6.7% of the persons and most were asymptomatic. Adult mosquito and larvae house indexes were not found associated with increased burden of disease. The only entomologic indicator related to dengue infection in humans was the pooled infection rate of mosquitoes. Aedes aegypti infection rates showed significant differences between the epidemic (10.68, 95% confidence interval [CI] = 7.04-15.62) and after epidemic periods of the study (6.15, 95% CI = 3.46-10.19). In addition, Ae. albopictus were also infected with dengue viruses. Increases in mosquito infection rates were associated with increases in human infection rates in the following trimester.
Méndez
Fabián
F
Grupo Epidemiología y Salud Poblacional, Escuela de Salud Pública, Universidad del Valle, Cali, Colombia. famendez@univalle.edu.co
Barreto
Mauricio
M
Arias
Juan F
JF
Rengifo
Graciela
G
Muñoz
Jaime
J
Burbano
María E
ME
Parra
Beatriz
B
D000818:Animals; D003105:Colombia / Q000453:epidemiology; D009033:Culicidae / Q000821:virology*; D003715:Dengue / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission / Q000821:virology; D003716:Dengue Virus / Q000235:genetics*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007303:Insect Vectors / Q000821:virology*; D008297:Male; D011446:Prospective Studies; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction
D012367:RNA, Viral