Structural insights into regulation of nuclear receptors by ligands.
Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction between selected nuclear receptors and their cognate ligands.
Xu
Eric H
EH
Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA. Eric.Xu@vai.org
Lambert
Millard H
MH