Relationships between dynamic contrast-enhanced MRI findings and pattern of invasion for tongue carcinoma.
The purpose of this study was to evaluate the effectiveness of dynamic contrast-enhanced MRI (DC-MRI) for assessing the pattern of invasion of tongue carcinomas. We studied 20 cases of squamous cell carcinoma of the tongue that showed peripheral enhancement patterns on DC-MRI. The diameter of each tumor was >2.0 cm and no apparent artifacts were seen. The signal enhancement to noise ratio (SE/N) of the regions of interest, which were located in the central and peripheral regions of the tumor, were measured using DC-MRI, while maximum SE/N, %-wash out, and the ascending rate of SE/N were also calculated. The histopathological pattern of invasion was assessed in each case and used to classify them into clear (13 cases) and diffuse (7 cases) groups, after which the 4 parameters were compared between the 2 groups. The ascending rate of SE/N in the peripheral region was significantly lower in the diffuse group (p=0.047). There were no other significant differences between the 2 groups for any parameter in either tumor region. These results suggest that DC-MRI is able to show the histopathological pattern of invasion into surrounding structures.
Ariyoshi
Yasunori
Y
Department of Oral Surgery, Osaka Medical College, Takatsuki City, Osaka 569-8686, Japan. ora009@poh.osaka-med.ac.jp
Shimahara
Masashi
M
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000175:diagnosis*; D014062:Tongue Neoplasms / Q000175:diagnosis*
D003287:Contrast Media; D019786:Gadolinium DTPA