title: [Acute disseminated encephalomyelitis due to hymenoptera stings].
abstract: BACKGROUND
  Hymenoptera stings can give rise to a variety of conditions. The most common is a self-limiting local allergic reaction, but occasionally they may produce potentially serious systemic reactions. Neurological complications are rare, but very varied and of differing degrees of severity. Some such consequences are those of a demyelinating nature, which can affect the central and/or peripheral nervous system. Their exact pathogenesis remains unknown but an autoimmune mechanism has been suggested.
  
  
  METHODS
  We report the case of a 28-year-old female who had a clinical picture compatible with acute disseminated encephalomyelitis ten days after being stung several times by a bumblebee. The diagnosis was based on findings from magnetic resonance imaging and on the clinical-radiological course after a one-year follow-up. The patient was treated with massive doses of intravenous corticosteroids and immunoglobulins, which brought about partial recovery from the neurological deficit.
  
  
  CONCLUSIONS
  Hymenoptera stings can produce demyelinating neurological complications, presumably related to the autoimmune system, which could benefit from treatment with immunomodulators such as corticosteroids, immunoglobulins or plasmapheresis.
authors.affiliation: Sección de Neurología, Hospital Torrecárdenas, Almería. peperubi@auna.com
authors.forename: J
authors.initials: J
authors.lastname: Rubí-Callejón
authors.forename: A
authors.initials: A
authors.lastname: Arjona
authors.forename: P J
authors.initials: PJ
authors.lastname: Serrano-Castro
authors.forename: G
authors.initials: G
authors.lastname: Alonso-Verdegay
authors.forename: A
authors.initials: A
authors.lastname: Huete-Hurtado
mesh_terms: D000328:Adult; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D006927:Hymenoptera; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007299:Insect Bites and Stings / Q000150:complications / Q000276:immunology; D008279:Magnetic Resonance Imaging
chemical_list: D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D003907:Dexamethasone