title: Pneumoconiosis associated with an esophageal ulcer and uptake revealed in FDGPET.
abstract: A 76-year-old man with a past history of pneumoconiosis visited the Department of Gastroenterology in our hospital suffering from dysphagia. Gastroscopy revealed an esophageal ulcer on the top of a torus lesion. Chest computed tomography (CT) revealed it was caused by a swollen lymph node in the mediastinum. Squamous cell carcinoma related antigen (SCC) was elevated to 1.8 ng/ml. To rule out malignancy, we performed fluorine-18 deoxyglucose positron emission tomography (FDGPET) which revealed a significantly increased uptake in a nodular lesion in the right upper lobe and mediastinal lymph nodes. Biopsy and cytology of the nodular lesion revealed only pneumoconiosis. We must be careful when we interpret the findings of FDGPET in pneumoconiosis patients.
authors.affiliation: Department of Respiratory Medicine, International Medical Center of Japan, Tokyo.
authors.forename: Takehito
authors.initials: T
authors.lastname: Shukuya
authors.forename: Go
authors.initials: G
authors.lastname: Naka
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kawana
authors.forename: Haruhito
authors.initials: H
authors.lastname: Sugiyama
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kudo
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Yago
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Tamegai
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kubota
mesh_terms: D000368:Aged; D001999:Bronchoscopy; D003238:Connective Tissue / Q000378:metabolism; D004935:Esophageal Diseases / Q000150:complications*; D019788:Fluorodeoxyglucose F18; D005773:Gastroscopy; D006801:Humans; D006965:Hyperplasia; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D016676:Macrophages, Alveolar / Q000378:metabolism; D008297:Male; D011009:Pneumoconiosis / Q000150:complications* / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014456:Ulcer / Q000150:complications*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18