title: [First reported cases of Streptococcus pyogenes meningitis in Central African Republic].
abstract: Streptococcus pyogenes or group A streptococcus is an uncommon cause of bacterial meningitis. The purpose of this report is to describe two cases of Streptococcus pyogenes meningitis observed in Bangui, Central African Republic. The first case occurred in a 44-year-old woman who also presented pyodermitis. The second case involved a 34-year-old woman who also presented chronic middle ear infection and AIDS. Both strains of Streptococcus pyogenes were classified as biotype group 5 and showed resistance to tetracycline. They were also T-nontypable and of the emm 117 genotype and 117.1 subtype. Pulsed-field gel electrophoresis confirmed that both strains originated from the same clone.
authors.affiliation: l'Institut Pasteur de Bangui République de Centrafrique. rbercion@pasteur-bangui.org
authors.forename: L
authors.initials: L
authors.lastname: Mihaila-Amrouche
authors.forename: C
authors.initials: C
authors.lastname: Bekondi
authors.forename: Y C
authors.initials: YC
authors.lastname: Kappe
authors.forename: A
authors.initials: A
authors.lastname: Bouvet
authors.forename: R
authors.initials: R
authors.lastname: Bercion
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D002488:Central African Republic; D005260:Female; D005838:Genotype; D006801:Humans; D016920:Meningitis, Bacterial / Q000175:diagnosis* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification / Q000187:drug effects / Q000235:genetics; D013753:Tetracycline Resistance