1,1'-Binaphthyl-2,2'-diyl phosphoroselenoyl chloride as a chiral molecular tool for the preparation of enantiomerically pure alcohols and amines.
Enantiomerically pure phosphoroselenoyl chloride bearing a binaphthyl group was synthesized. This phosphoroselenoyl chloride was used to discriminate and resolve simple secondary alcohols. Stereospecific conversions of diastereomerically pure phosphoroselenoic acid esters, obtained by reaction of the chloride with simple secondary alcohols, to enantiomerically pure alcohols and amines were also achieved.
Murai
Toshiaki
T
Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, Gifu 501-1193 Japan. mtoshi@cc.gifu-u.ac.jp
Matsuoka
Daichi
D
Morishita
Ken
K