title: Actinomycotic brain infection: registered diffusion, perfusion MR imaging and MR spectroscopy.
abstract: BACKGROUND
  Actinomycotic brain infection is caused by an organism of the Actinomyces genus. We report here one such case.
  
  
  METHODS
  The methods used included coregistered diffusion, perfusion and spectroscopic magnetic resonance (MR) imaging.
  
  
  RESULTS
  Decreased apparent diffusion coefficient, markedly elevated fractional anisotropy (FA) and reduced cerebral blood flow were observed. MR spectroscopy demonstrated elevated amino acids, acetate and succinate.
  
  
  CONCLUSIONS
  Elevated FA values may be due to the microstructure of this special brain infection.
authors.affiliation: Department of Radiology, Division of Neuroradiology, Hospital of the University of Pennsylvania, 219 Dulles Building, 3400 Spruce Street, Philadelphia, PA 19104, USA. poptanih@uphs.upenn.edu
authors.forename: Sumei
authors.initials: S
authors.lastname: Wang
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Wolf
authors.forename: John H
authors.initials: JH
authors.lastname: Woo
authors.forename: Jiongjiong
authors.initials: J
authors.lastname: Wang
authors.forename: Donald M
authors.initials: DM
authors.lastname: O'Rourke
authors.forename: Subhojit
authors.initials: S
authors.lastname: Roy
authors.forename: Elias R
authors.initials: ER
authors.lastname: Melhem
authors.forename: Harish
authors.initials: H
authors.lastname: Poptani
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis*; D001927:Brain Diseases / Q000175:diagnosis* / Q000382:microbiology*; D003287:Contrast Media; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media