title: [Mandibular resorption, an underdiagnosed manifestation of systemic scleroderma].
abstract: BACKGROUND
  Systemic sclerosis (SSc) is sometimes associated with bone resorption that can reach the mandible.
  
  
  METHODS
  We report here the cases of two women (aged 47 and 57 years) with SSc diagnosed 13 and 26 years earlier, respectively. Both presented marked mandibular bone resorption. The first had prominent interstitial lung disease, and the second, who died within a few months, had severe left ventricular dysfunction due to SSc.
  
  
  CONCLUSIONS
  Mandibular resorption is a rare but probably underdiagnosed manifestation of SSc. In addition to its esthetic effects, it can cause severe disability.
authors.affiliation: Université Paris-Descartes, Faculté de Médecine, Service de Médecine Interne, Centre de Référence National pour la Sclérodermie et les Vascularites Systémiques, Hôpital Cochin, AP-HP, Paris.
authors.forename: Pierre
authors.initials: P
authors.lastname: Charles
authors.forename: Alice
authors.initials: A
authors.lastname: Berezné
authors.forename: Loïc
authors.initials: L
authors.lastname: Guillevin
authors.forename: Luc
authors.initials: L
authors.lastname: Mouthon
mesh_terms: D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed