title: Reusable polymer-supported catalyst for the [3+2] Huisgen cycloaddition in automation protocols.
abstract: [reaction: see text] A polymer-supported catalyst for Huisgen's [3+2] cycloaddition reaction between azides and alkynes was prepared from copper(I) iodide and Amberlyst A-21. This catalyst was then used in an automated synthesis of 1,4-disubstituted 1,2,3-triazoles giving access to these products in good yields. The catalyst has shown good activity, stability, and recycling capabilities.
authors.affiliation: Inserm, U640, Paris, F-75006 France. christian-girard@enscp.fr
authors.forename: Christian
authors.initials: C
authors.lastname: Girard
authors.forename: Esra
authors.initials: E
authors.lastname: Onen
authors.forename: Marie
authors.initials: M
authors.lastname: Aufort
authors.forename: Sophie
authors.initials: S
authors.lastname: Beauvière
authors.forename: Edmond
authors.initials: E
authors.lastname: Samson
authors.forename: Jean
authors.initials: J
authors.lastname: Herscovici