Management of diabetic foot in a Jordanian hospital.
The effect of different antibiotics on the outcome of surgical care in the management of diabetic foot was investigated. We randomly allocated 100 patients with diabetic foot into one of four groups. Each patient's infection was graded (Wagner classification). All patients were offered the same surgical care but each group was assigned a different antibiotic. Hospital stay for the four groups ranged from 7 to 14 days. Five patients experienced complications from septicaemia; 15 patients underwent amputation; and five patients experienced temporary renal impairment. Careful consideration to the type of antibiotic used is essential.
Al-Ebous
A D
AD
Royal Medical Services, Amman, Jordan. aalebous@hotmail.com
Hiasat
B
B
Sarayrah
M
M
Al-Jahmi
M
M
Al-Zuriqat
A N
AN
D000583:Amikacin / Q000627:therapeutic use; D000671:Amputation, Surgical / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002442:Ceftazidime / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003646:Debridement / Q000009:adverse effects; D017719:Diabetic Foot / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D004338:Drug Combinations; D016903:Drug Monitoring; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D007674:Kidney Diseases / Q000209:etiology; D007902:Length of Stay / Q000706:statistics & numerical data; D008034:Lincomycin / Q000627:therapeutic use; D008795:Metronidazole / Q000627:therapeutic use; D018579:Patient Selection; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D018805:Sepsis / Q000209:etiology; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014945:Wound Healing; D014946:Wound Infection / Q000209:etiology / Q000517:prevention & control
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D008795:Metronidazole; D000077725:Piperacillin, Tazobactam Drug Combination; D015378:Imipenem; D000583:Amikacin; D010397:Penicillanic Acid; D002442:Ceftazidime; D008034:Lincomycin; D010878:Piperacillin