A polymorphism of the interleukin 1 receptor antagonist is not associated with polycystic ovary syndrome in Caucasian women.
In a prospective case-control study we investigated the association of a common polymorphism of the interleukin 1 receptor antagonist gene (IL-1 RA) with the occurrence and the clinical characteristics of polycystic ovary syndrome (PCOS). Allele frequencies did not vary statistically significantly among women with PCOS and healthy controls or within the PCOS group with respect to their clinical characteristics.
Kolbus
Andrea
A
Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria. andrea.kolbus@meduniwien.ac.at
Walch
Katharina
K
Szabo
Laszlo
L
Huber
Johannes C
JC
Nagele
Friedrich
F
Unfried
Gertrud
G
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D011085:Polycystic Ovary Syndrome / Q000235:genetics*; D011110:Polymorphism, Genetic; D011446:Prospective Studies; D012795:Sialoglycoproteins / Q000235:genetics*; D044465:White People / Q000235:genetics*
C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D012795:Sialoglycoproteins