[Is anti-hyperalgesia clinically relevant? Dosage increase is hardly necessary].
D000279:Administration, Cutaneous; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects; D002047:Buprenorphine / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D006930:Hyperalgesia / Q000175:diagnosis / Q000188:drug therapy*; D009020:Morphine / Q000008:administration & dosage / Q000009:adverse effects; D017288:Pain Threshold / Q000187:drug effects*; D016896:Treatment Outcome
D000701:Analgesics, Opioid; D002047:Buprenorphine; D009020:Morphine; D005283:Fentanyl