title: Temporary phosphate tethers: a metathesis strategy to differentiated polyol subunits.
abstract: [reaction: see text] Studies probing reactivity and selectivity of cross metathesis (CM) with an exocyclic olefin in a P-chiral bicyclo[4.3.1]phosphate triester are described. Studies have revealed a Type III CM reactivity pattern for the exocyclic olefin within this phosphate triester. This versatile method allows for simple, selective manipulation of a P-chiral building block en route to advanced polyol subunits.
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045-7582, USA.
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Waetzig
authors.forename: Paul R
authors.initials: PR
authors.lastname: Hanson
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D009943:Organophosphorus Compounds; D011108:Polymers; C024617:polyol