title: Determination of usnic acid in some Rhizoplaca species from Middle Anatolia and their antimicrobial activities.
abstract: Three species of lichens, Rhizoplaca chrysoleuca (Sm.) Zopf, Rhizoplaca melanopthalma (DC.) Leuckert & Poelt and Rhizoplaca peltata Ramonds Leuckert, were collected from middle Anatolia, Erciyes Mountain (Kayseri) in Turkey. Their usnic acid amounts were determined by HPLC in acetone extracts. In addition, antimicrobial activities of these extracts were determined against Escherichia coli (ATCC 35218), Enterococcus faecalis (RSKK 508), Proteus mirabilis (Pasteur Ens. 235), Staphylococcus aureus, Bacillus subtilis, Bacillus megaterium and Pseudomonas aeruginosa. It was shown that, as the usnic acid amount increased, the antimicrobial activities increased too. The usnic acid contents of Rhizoplaca species varied between 0.19-4.0% dry weight.
authors.affiliation: Botany Section, Department of Biology, Faculty of Science, University of Ankara, Tandogán 06100 Ankara, Turkey. cansaran@science.ankara.edu.tr
authors.forename: Demet
authors.initials: D
authors.lastname: Cansaran
authors.forename: Demet
authors.initials: D
authors.lastname: Cetin
authors.forename: M Gökhan
authors.initials: MG
authors.lastname: Halici
authors.forename: Orhan
authors.initials: O
authors.lastname: Atakol
mesh_terms: D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D001407:Bacillus / Q000187:drug effects; D001572:Benzofurans / Q000302:isolation & purification / Q000494:pharmacology*; D002138:Calibration; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008011:Lichens / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D011513:Proteus mirabilis / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014421:Turkey
chemical_list: D000890:Anti-Infective Agents; D001572:Benzofurans; C073339:usnic acid