title: Total synthesis of (+/-)-galanthamine.
abstract: [reaction: see text] A practical and efficient total synthesis of (+/-)-galanthamine was achieved from commercially available materials through a novel approach, in which the construction of its core structure and the special allylic alcohol group were based on a successive semipinacol rearrangement/desilyation/cyclization and Saegusa-Ito oxidation, respectively.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, PRC.
authors.forename: Xiang-Dong
authors.initials: XD
authors.lastname: Hu
authors.forename: Yong Qiang
authors.initials: YQ
authors.lastname: Tu
authors.forename: En
authors.initials: E
authors.lastname: Zhang
authors.forename: Shuanhu
authors.initials: S
authors.lastname: Gao
authors.forename: Shaohua
authors.initials: S
authors.lastname: Wang
authors.forename: Aixia
authors.initials: A
authors.lastname: Wang
authors.forename: Chun-An
authors.initials: CA
authors.lastname: Fan
authors.forename: Min
authors.initials: M
authors.lastname: Wang
mesh_terms: D002384:Catalysis; D003500:Cyclization; D005702:Galantamine / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D005702:Galantamine