Leiomyosarcoma of the bladder in a 16-year-old girl with a history of cyclophosphamide therapy for bilateral retinoblastoma during infancy.
A 16-year-old female with bladder leiomyosarcoma had a history of bilateral retinoblastoma at 6 months of life. She received cyclophosphamide chemotherapy after surgical enucleation. In this report, we discussed the possible role of retinoblastoma or cyclophosphamide as a target for the development of bladder leiomyosarcoma.
Al-Zahrani
Ali A
AA
Department of Urology and Pathology, King Faisal University, King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia. ahzhrani@yahoo.com
Kamal
Baher A
BA
Eldarawani
Hamed M
HM
Hashim
Tariq M
TM
D000293:Adolescent; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D003520:Cyclophosphamide / Q000009:adverse effects*; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D007223:Infant; D007890:Leiomyosarcoma / Q000139:chemically induced*; D019572:Retinal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D012175:Retinoblastoma / Q000188:drug therapy* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced*
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide