title: Ion release from gold/platinum dental alloy: could release of other elements be accountable in the contact allergy attributed to the gold?
abstract: OBJECTIVE
  The release of metal ions (Al, Ag, Au, Ca, Cd, Co, Cr, Cu, Mg, Mo, Ni, Pd, Pt, Ti, and Zn) from the commercial gold/platinum (Au/Pt) dental alloy of declared composition was studied.
  
  
  METHODS
  Au/Pt was soaked in pH 6.0 phosphate buffer, 3.5 pH phosphate buffer and pH 3.5 mixture of lactic, formic and acetic acid, and incubated at 37 degrees C for 1, 2, 3, 4, 5, 6, 7, 14, 21, and 30 days. Six samples (n = 6) of every solution were prepared for any time period. Inductively coupled plasma atomic emission spectroscopy was used for analysis of the released elements.
  
  
  RESULTS
  Results demonstrated release of only Cr, Cu, Fe, and Zn from the tested Au/Pt dental alloy (ANOVA, p < 0.001 for buffer, time, and interaction, respectively); however, only Cu and Zn were declared.
  
  
  CONCLUSIONS
  The undeclared chromium from Au/Pt dental alloy, or some other element might be responsible for the contact allergy thus far attributed to the gold.
authors.affiliation: School of Dental Medicine, University of Zagreb, Gundulićeva 5, Zagreb, Croatia. celebic@sfzg.hr
authors.forename: A
authors.initials: A
authors.lastname: Celebić
authors.forename: M
authors.initials: M
authors.lastname: Baucić
authors.forename: J
authors.initials: J
authors.lastname: Stipetić
authors.forename: I
authors.initials: I
authors.lastname: Baucić
authors.forename: S
authors.initials: S
authors.lastname: Miko
authors.forename: B
authors.initials: B
authors.lastname: Momcilović
mesh_terms: D003722:Dental Alloys / Q000009:adverse effects* / Q000737:chemistry*; D003877:Dermatitis, Contact / Q000209:etiology*; D006046:Gold / Q000009:adverse effects / Q000737:chemistry; D006801:Humans; D007477:Ions; D008422:Materials Testing; D008670:Metals / Q000009:adverse effects* / Q000737:chemistry*; D010984:Platinum / Q000009:adverse effects / Q000737:chemistry; D018570:Risk Assessment; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry*
chemical_list: D003722:Dental Alloys; D007477:Ions; D008670:Metals; D010984:Platinum; D006046:Gold