Bosentan may induce arthritis flare in patients with scleroderma concomitantly treated with methotrexate.
Cozzi
F
F
Ostuni
P A
PA
Marotta
H
H
Sfriso
P
P
Favaro
M
M
Todesco
S
S
D000959:Antihypertensive Agents / Q000009:adverse effects*; D001168:Arthritis / Q000139:chemically induced*; D000077300:Bosentan; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy; D008727:Methotrexate / Q000009:adverse effects*; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000188:drug therapy*; D013449:Sulfonamides / Q000009:adverse effects*
D000959:Antihypertensive Agents; D013449:Sulfonamides; D000077300:Bosentan; D008727:Methotrexate