Hyosgerin, a new optically active coumarinolignan, from the seeds of Hyoscyamus niger.
Hyosgerin, a new optically active coumarinolignan, has been isolated and characterized along with three other coumarinolignans, venkatasin, cleomiscosin A and cleomiscosin B, from the seeds of Hyoscyamus niger L. The structure was determined on the basis of spectroscopic analysis and chemical conversion. The optical properties and absolute stereochemistry of these coumarinolignans have also been studied and discussed.
Sajeli
Begum
B
Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. sajeli1@rediffmail.com
Sahai
Mahendra
M
Suessmuth
Roderich
R
Asai
Teigo
T
Hara
Noriyuki
N
Fujimoto
Yoshinori
Y
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004146:Dioxanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D032304:Hyoscyamus / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D009904:Optical Rotation; D010946:Plants, Medicinal; D012639:Seeds / Q000737:chemistry*; D013057:Spectrum Analysis; D013237:Stereoisomerism
D003374:Coumarins; D004146:Dioxanes; D017705:Lignans; C511093:hyosgerin; C041934:cleomiscosin A