Synthesis and herbicidal activity of novel alpha,alpha,alpha-trifluoro-m-tolyl pyridazinone derivatives.
A series of novel alpha,alpha,alpha-trifluoro-m-tolyl pyridazinone derivatives was synthesised. Herbicidal activities of the two intermediate compounds and 15 pyridazinone derivatives were evaluated through barnyardgrass and rape cup tests and Spirodela polyrrhiza (L.) Schleiden tests. Selected compounds were also evaluated under greenhouse conditions. Bleaching activities were observed at 10 microg ml(-1) and some compounds exhibited herbicidal activities at a rate of 300 g ha(-1). The relationship between crystal structures and herbicidal activities is discussed through a comparison of two compounds (5a and 5f).
Xu
Han
H
State Key Laboratory of Elemento-Organic Chemistry, Elemento-Organic Chemistry Institute, Nankai University, Tianjin 300071, China.
Zou
Xiao-Mao
XM
Zhu
You-Quan
YQ
Liu
Bin
B
Tao
Han-Lin
HL
Hu
Xu-Hong
XH
Song
Hai-Bin
HB
Hu
Fang-Zhong
FZ
Wang
Yong
Y
Yang
Hua-Zheng
HZ
D001937:Brassica / Q000187:drug effects / Q000254:growth & development; D031747:Echinochloa / Q000187:drug effects / Q000254:growth & development; D006540:Herbicides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000187:drug effects; D011724:Pyridazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
D006540:Herbicides; D011724:Pyridazines