title: Drug-induced lung diseases: most common reaction patterns and corresponding high-resolution CT manifestations.
abstract: Drug-induced lung disease is an increasingly common cause of morbidity and mortality. The diagnosis is based on clinical history and consistent radiologic findings. Lung biopsy is performed in a small percentage of cases. High-resolution CT may demonstrate parenchymal abnormalities in patients with normal radiographs and provides a better depiction of the pattern and distribution of findings. Knowledge of the most common high-resolution CT manifestations and the corresponding histologic patterns is important for early recognition and proper management of drug-induced lung disease.
authors.affiliation: Department of Radiology, Vancouver General Hospital, University of British Columbia, 899 W. 12th Avenue, Vancouver, BC, Canada V5Z 1M9.
authors.forename: C Isabela S
authors.initials: CI
authors.lastname: Silva
authors.forename: Nestor L
authors.initials: NL
authors.lastname: Müller
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic / Q000379:methods*; D014057:Tomography, X-Ray Computed