title: Synthesis of 1,4-anhydro-D-fructose and 1,4-anhydro-D-tagatose.
abstract: 1,4-Anhydro-D-fructose and 1,4-anhydro-D-tagatose were prepared from 1,2-O-isopropylidene-D-glucofuranose via the common intermediate 3,5,6-tri-O-benzyl-D-glucitol. The title compounds may be interesting anti-oxidants and feature activities akin to their natural pyranoid counterpart, 1,5-anhydro-D-fructose.
authors.affiliation: Glycom ApS, Department of Chemistry, Technical University of Denmark (DTU), Building 201, DK-2800 Kgs. Lyngby, Denmark.
authors.forename: Gyula
authors.initials: G
authors.lastname: Dekany
authors.forename: Inge
authors.initials: I
authors.lastname: Lundt
authors.forename: Andreas J
authors.initials: AJ
authors.lastname: Steiner
authors.forename: Arnold E
authors.initials: AE
authors.lastname: Stütz
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D005632:Fructose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: C512762:1,4-anhydrofructose; C512763:1,4-anhydrotagatose; D000975:Antioxidants; D005632:Fructose; C048927:1,5-anhydrofructose