Spinal extramedullary anaplastic ependymoma with spinal and intracranial metastases.
We describe a 29-year-old woman who presented with progressive neck pain, sensory deficit and weakness in both arms. Magnetic resonance imaging (MRI) of the cervical spine revealed an extramedullary tumor with severe spinal cord compression. During surgery an intradural extramedullary tumor was found. Further imaging showed a second lumbar spinal tumor. Microscopy of both tumors showed that both tumors were anaplastic ependymomas, which almost never present as extramedullary tumors. Two years after surgery, an intracranial extracerebral metastasis was found, without evidence of spinal recurrence.
Schuurmans
Mascha
M
Department of Neurology, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands. m.schuurmans@slaz.nl
Vanneste
Jan A L
JA
Verstegen
Marco J T
MJ
van Furth
Wouter R
WR
D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary*; D002574:Cervical Vertebrae; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000378:metabolism; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D009418:S100 Proteins / Q000378:metabolism; D013120:Spinal Cord Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology
D019394:Ki-67 Antigen; D009418:S100 Proteins