Percutaneous coronary intervention versus thrombolysis: the definite management of st elevation myocardial infarction.
The management of an ST elevation myocardial infarction has undergone significant changes in the past few years. Fibrinolytic agents have become more and more clot specific increasing their efficacy. However, percutaneous coronary intervention, along with its adjuvant therapy (glycoprotein IIB/IIIA receptor inhibitors and clopidrogel), have come to challenge fibrinolytic use. Many studies have demonstrated the benefits of percutaneous coronary intervention as compared to fibrinolysis in the management of acute myocardial infarction by decreasing infarct size, myocardial function loss, and mortality.
Martinez-Ojeda
Jose
J
Cadiology Fellow, University Hospital, University of Puerto Rico, School of Medicine, San Juan. josemartinez00@hotmail.com
Martinez-Toro
Jose
J
D000367:Age Factors; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D000077144:Clopidogrel; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D015337:Multicenter Studies as Topic; D009203:Myocardial Infarction / Q000188:drug therapy / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D016032:Randomized Controlled Trials as Topic; D012770:Shock, Cardiogenic / Q000628:therapy; D015607:Stents; D013318:Stroke Volume; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000502:physiology
D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D000077144:Clopidogrel; D013988:Ticlopidine