title: Nicobrevin for smoking cessation.
abstract: BACKGROUND
  Nicobrevin is a proprietary product marketed as an aid to smoking cessation. It contains quinine, menthyl valerate, camphor and eucalyptus oil.
  
  
  OBJECTIVE
  The objective of this review was to assess the effects of Nicobrevin on long term smoking cessation
  
  
  METHODS
  We searched the Cochrane Tobacco Addiction Group trials register.
  
  
  METHODS
  Randomized trials comparing Nicobrevin to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow up.
  
  
  METHODS
  Data were sought on the outcome, method of randomization, and completeness of follow up.
  
  
  RESULTS
  We identified no trials meeting the full inclusion criteria including long-term follow up.
  
  
  CONCLUSIONS
  There is no evidence available from long-term trials that Nicobrevin can aid smoking cessation.
authors.affiliation: Oxford University, Department of Primary Health Care, Old Road Campus, Headington, Oxford, UK, OX3 7LF. lindsay.stead@dphpc.ox.ac.uk
authors.forename: L F
authors.initials: LF
authors.lastname: Stead
authors.forename: T
authors.initials: T
authors.lastname: Lancaster
mesh_terms: D006801:Humans; D010421:Pentanoic Acids / Q000627:therapeutic use*; D011803:Quinine / Q000627:therapeutic use*; D016540:Smoking Cessation; D000074606:Smoking Prevention; D013729:Terpenes / Q000627:therapeutic use*
chemical_list: D010421:Pentanoic Acids; D013729:Terpenes; C060496:nicobrevin; D011803:Quinine