title: Synthesis of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-alkyl amides and their antioxidant activity.
abstract: A series of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-alkyl amides (3a-g) were synthesized and their antioxidant activities were evaluated using rat brain homogenates.
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, Korea.
authors.forename: Jungsook
authors.initials: J
authors.lastname: Cho
authors.forename: Hae-Eun
authors.initials: HE
authors.lastname: Kang
authors.forename: Jae-Kyung
authors.initials: JK
authors.lastname: Jung
authors.forename: Heesoon
authors.initials: H
authors.lastname: Lee
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002839:Chromans / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000138:chemical synthesis* / Q000494:pharmacology; D015227:Lipid Peroxidation; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D000577:Amides; D001578:Benzopyrans; D002839:Chromans; D016166:Free Radical Scavengers; C010643:6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid