title: Phytotherapy: rarely mentioned spontaneously.
abstract: (1) In a German study, very few patients informed their healthcare providers that they were taking St John's wort. (2) St John's wort is an enzyme inducer and can therefore accelerate the elimination of many drugs, including vitamin K antagonists, hormonal contraceptives and immunosuppressants. This leads to a potential loss of efficacy of these drugs when taken in combination with St John's wort. On the other hand, there may be a risk of overdose when St John's wort is withdrawn. (3) In practice, patients must be carefully questioned about all treatments they are taking, including herbal products they do not consider worth mentioning.
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000009:adverse effects; D030881:Disclosure; D004347:Drug Interactions; D006801:Humans; D020902:Hypericum / Q000009:adverse effects; D008487:Medical History Taking; D010696:Phloroglucinol / Q000009:adverse effects / Q000031:analogs & derivatives; D008517:Phytotherapy / Q000009:adverse effects*; D013729:Terpenes / Q000009:adverse effects
chemical_list: D001643:Bridged Bicyclo Compounds; D013729:Terpenes; D010696:Phloroglucinol