[New strategies in multiple organ dysfunction syndrome therapy for sepsis].
Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids), all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient.
Surbatović
Maja
M
Radaković
Sonja
S
Jovanović
Krsta
K
Romić
Predrag
P
D006801:Humans; D009102:Multiple Organ Failure / Q000209:etiology / Q000628:therapy*; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000628:therapy*