title: A new active compound from Centaurea species.
abstract: The extract containing sesquiterpene lactones of Centaurea iberica (Asteraceae) isolated was separated and a steroidal compound, which is stigmast-1,5-dien-3beta-ol, was purified. The chemical structure was established based on spectroscopic data (UV, IR, MS, 1H NMR, 13C NMR). Both the extract and the compound showed significant antioxidant and antimicrobial activities.
authors.affiliation: Marmara University, Faculty of Pharmacy, Department of Pharmacognosy, Istanbul, Turkey. melekulusoylu@hotmail.com
authors.forename: Melek U
authors.initials: MU
authors.lastname: Dumlu
authors.forename: Elcin
authors.initials: E
authors.lastname: Gürkan
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology*; D001156:Artemia / Q000187:drug effects; D031179:Centaurea / Q000737:chemistry*; D010084:Oxidation-Reduction; D010578:Petroleum; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D000975:Antioxidants; D010578:Petroleum; D010936:Plant Extracts; D013256:Steroids