Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays.
[structure: see text] Small molecule macroarrays of cyanopyridines and deazalumazines were generated in high purities via spatially addressed synthesis on planar cellulose supports. Examination of the spectral properties of the heterocycles both on and off of the planar support revealed a set of promising new fluorescent dyes that exhibit high quantum yields, low pH dependence, and high sensitivity to solvent polarity.
Bowman
Matthew D
MD
Department of Chemistry, University of Wisconsin-Madison, 1101 University Ave., Madison, Wisconsin 53706-1322, USA.
Jacobson
Megan M
MM
Blackwell
Helen E
HE