title: Pulmonary sarcoidosis with usual interstitial pneumonia distributed predominantly in the lower lung fields.
abstract: Nodular and reticular opacities were detected in both lower lung fields of a 75-year-old man in 2000. Bronchoscopy revealed pulmonary sarcoidosis. In 2002, nodular and reticular opacities were shown in the right upper lobe, and video-assisted thoracoscopic surgery was performed. The histological findings revealed usual interstitial pneumonia (UIP)-like lesions, whereas non-caseous granulomas were not detected. In the present case of pulmonary sarcoidosis, nodular and reticular opacities were predominantly distributed in both lower lung fields, and the histological findings obtained by video-assisted thoracoscopic surgery showed UIP-like lesions. These findings may enlighten the assist in understanding of the process of development of pulmonary sarcoidosis.
authors.affiliation: Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nobata
authors.forename: Takahiko
authors.initials: T
authors.lastname: Kasai
authors.forename: Masaki
authors.initials: M
authors.lastname: Fujimura
authors.forename: Masayuki
authors.initials: M
authors.lastname: Mizuguchi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nishi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Ishiura
authors.forename: Masahide
authors.initials: M
authors.lastname: Yasui
authors.forename: Shinji
authors.initials: S
authors.lastname: Nakao
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008168:Lung / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D008297:Male; D018396:Mucin-1; D009077:Mucins / Q000032:analysis; D009113:Muramidase / Q000097:blood; D007703:Peptidyl-Dipeptidase A / Q000097:blood; D011239:Prednisolone / Q000008:administration & dosage; D011859:Radiography; D017565:Sarcoidosis, Pulmonary / Q000276:immunology / Q000473:pathology*; D013906:Thoracoscopy
chemical_list: D000951:Antigens, Neoplasm; D005938:Glucocorticoids; C060192:MUC1 protein, human; D018396:Mucin-1; D009077:Mucins; D011239:Prednisolone; D009113:Muramidase; D007703:Peptidyl-Dipeptidase A