title: How we do it: surgery should be considered equally with I131 and thionamide treatment as first-line therapy for thyrotoxicosis.
abstract: Radioiodine and thionamide treatment are the most frequently used treatment modalities for thyrotoxicosis in Europe and North America with surgery being reserved for selected cases. * In our clinic patients were offered all three modalities via simultaneous interview with an endocrinologist and a surgeon, with international risk benefit data for radioiodine and thionamide therapy, and local risk benefit data for total thyroidectomy provided. * When given the choice, at least 15% of patients opted for total thyroidectomy over the other modalities. * In our series of 100 consecutive surgical patients there was a 4% malignancy rate. * Total thyroidectomy should be offered equally, with radioiodine and thionamide treatment, as a first line treatment modality in the management of thyrotoxicosis.
authors.affiliation: Departments of Otolaryngology Head and Neck Surgery and Endocrinology, Hull Royal Infirmary, UK. rjaeathome@aol.com
authors.forename: R J A
authors.initials: RJ
authors.lastname: England
authors.forename: M B
authors.initials: MB
authors.lastname: Kamath
authors.forename: A
authors.initials: A
authors.lastname: Jabreel
authors.forename: G
authors.initials: G
authors.lastname: Dunne
authors.forename: S L
authors.initials: SL
authors.lastname: Atkin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D013956:Antithyroid Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013965:Thyroidectomy; D013971:Thyrotoxicosis / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D013956:Antithyroid Agents; D007457:Iodine Radioisotopes