title: Molecular characterization and drug resistance testing of Mycobacterium tuberculosis isolates from Chad.
abstract: The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodrug resistance. In total, 9/33 (27%) isolates were resistant to isoniazid. The implications of these findings are discussed.
authors.affiliation: Swiss Tropical Institute, Socinstrasse 57, P.O. Box CH 4002, Basel, Switzerland.
authors.forename: Colette
authors.initials: C
authors.lastname: Diguimbaye
authors.forename: Markus
authors.initials: M
authors.lastname: Hilty
authors.forename: Richard
authors.initials: R
authors.lastname: Ngandolo
authors.forename: Hassane H
authors.initials: HH
authors.lastname: Mahamat
authors.forename: Gaby E
authors.initials: GE
authors.lastname: Pfyffer
authors.forename: Franca
authors.initials: F
authors.lastname: Baggi
authors.forename: Marcel
authors.initials: M
authors.lastname: Tanner
authors.forename: Esther
authors.initials: E
authors.lastname: Schelling
authors.forename: Jakob
authors.initials: J
authors.lastname: Zinsstag
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D002596:Chad / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid