Anti-GAD antibody cerebellar ataxia mimicking Creutzfeldt-Jakob disease.
In a patient with a rapidly progressive neurological condition with ataxia and cognitive complaints, Creutzfeldt-Jakob disease (CJD) is often high in the differential, particularly when there is an elevated CSF 14-3-3 protein level. We present a case of anti-glutamic acid decarboxylase antibody (anti-GAD65) positive cerebellar ataxia associated with cognitive complaints and elevated CSF 14-3-3 protein.
Chang
Chiung-Chih
CC
University of California San Francisco, Department of Neurology, Memory & Aging Center, Box 1207, San Francisco, CA 94143-1207, USA.
Eggers
Scott D
SD
Johnson
Julene K
JK
Haman
Aissa
A
Miller
Bruce L
BL
Geschwind
Michael D
MD
D048948:14-3-3 Proteins / Q000134:cerebrospinal fluid; D000906:Antibodies / Q000378:metabolism*; D002524:Cerebellar Ataxia / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005968:Glutamate Decarboxylase / Q000276:immunology*; D006801:Humans; D008875:Middle Aged
D048948:14-3-3 Proteins; D000906:Antibodies; D005968:Glutamate Decarboxylase