title: The metabolic syndrome: relationship between insulin sensitivity and the role of peroxisome proliferator-activated receptors (PPARs) in saccharide and lipid metabolism.
abstract: Peroxisome proliferator-activated receptors (PPARs) are subgroups of nuclear hormonal receptors of transcripting factors mostly found in adipose tissue. They are described as important regulators of lipid and saccharide metabolism including insulin sensitivity; therefore they are taken as marker of metabolic syndrome. Their synthetic ligands could be used as drugs for insulin resistance and type 2 diabetes mellitus.
authors.affiliation: Institute of Physiology, Palacký University, 775 15 Olomouc, Czech Republic. yahiarab@yahoo.com
authors.forename: Rabha Ben
authors.initials: RB
authors.lastname: Yahia
authors.forename: Radka
authors.initials: R
authors.lastname: Lichnovská
authors.forename: Tomás
authors.initials: T
authors.lastname: Brychta
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D024821:Metabolic Syndrome / Q000378:metabolism*; D047492:Peroxisome Proliferator-Activated Receptors / Q000502:physiology*
chemical_list: D047492:Peroxisome Proliferator-Activated Receptors; D005947:Glucose