[Drug-induced dermatological pathology in renal transplantation patients].
The broad spectrum of muco-cutaneous manifestations of renal transplantation patients correlates mainly with immunosuppressive therapy. Our study refers to 56 patients with renal transplantation (29 women and 27 men) followed up in the Dialysis and Renal Transplantation Center of Parhon University Hospital Iaşi from November 2000 till October 2003. The most frequent muco-cutaneous manifestations were: infectious complications in 18 cases (32.1%), gum hyperplasia in 14 cases(25%), acne in 11 cases (19.6%), skin hyperpigmentation in 7 cases (12.5%), oral candidiasis in 6 cases (10.7%), vascular fragility in 5 cases (8.9%), hypertrichosis in 5 cases (8.9%), itching in 3 cases (5.3%), facial erythema in 3 cases (5.3%), full-moon facies in 3 cases (5.3%). These manifestations, often with unclear pathogenesis, are dose-related and almost unavoidable.
Tăranu
Tatiana
T
Universitatea de Medicină şi Farmacie Gr T Popa Iaşi, Facultatea de Medicină Dentară, Spitalul Universitar C F Iaşi, Clinica Dermatologică.
Covic
A
A
Buhăescu
Irina
I
Tăranu
Tr
T
D000293:Adolescent; D000328:Adult; D002180:Candidiasis, Oral / Q000139:chemically induced; D003875:Drug Eruptions / Q000209:etiology; D004890:Erythema / Q000139:chemically induced; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced; D006983:Hypertrichosis / Q000139:chemically induced; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012871:Skin Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012874:Skin Diseases, Infectious / Q000139:chemically induced
D007166:Immunosuppressive Agents