title: Gadolinium-chlorin is potentially a new tumor specific MRI contrast agent.
abstract: In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.
authors.affiliation: PDT BIO CO Ltd, Seoul, Korea.
authors.forename: Jong-Ki
authors.initials: JK
authors.lastname: Kim
authors.forename: Dong-myung
authors.initials: DM
authors.lastname: Kim
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Kang
authors.forename: Hae-Kyung
authors.initials: HK
authors.lastname: Kim
authors.forename: Jeong-Sook
authors.initials: JS
authors.lastname: Kim
authors.forename: Eun-Kyung
authors.initials: EK
authors.lastname: Yu
authors.forename: Jin-Hyun
authors.initials: JH
authors.lastname: Jeong
mesh_terms: D003287:Contrast Media / Q000138:chemical synthesis*; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D008665:Metalloporphyrins / Q000138:chemical synthesis*; D019047:Phantoms, Imaging; D017319:Photosensitizing Agents / Q000138:chemical synthesis
chemical_list: D003287:Contrast Media; D008665:Metalloporphyrins; D017319:Photosensitizing Agents; C511720:gadolinium-chlorin