title: Endovascular embolization of visceral artery aneurysms with ethylene-vinyl alcohol (Onyx): a case series.
abstract: We report the application of the liquid embolic agent ethylene-vinyl alcohol (Onyx; MicroTherapeutics, Irvine, CA, USA) in the management of visceral artery aneurysms. The technique and indications for using Onyx are discussed with emphasis on the management of wide-necked aneurysms and maintenance of patency of the parent vessel. None of the cases was considered suitable for stent-grafting or embolization with conventional agents. Two aneurysms of the renal artery bifurcation and one aneurysm of the inferior pancreaticoduodenal artery were treated. Following treatment there was complete exclusion of all aneurysms. There was no evidence of end-organ infarction. Follow-up with intervals up to 6 months has shown sustained aneurysm exclusion. Onyx is known to be effective in the management of intracranial aneurysms. Our experience demonstrates the efficacy and applicability of the use of Onyx in the treatment of complex visceral artery aneurysms.
authors.affiliation: Department of Radiology, St. George's Hospital, Ground Floor, St. James' Wing, Blackshaw Road, Tooting, London, SW17 0JT, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Bratby
authors.forename: E D
authors.initials: ED
authors.lastname: Lehmann
authors.forename: J
authors.initials: J
authors.lastname: Bottomley
authors.forename: D O
authors.initials: DO
authors.lastname: Kessel
authors.forename: A A
authors.initials: AA
authors.lastname: Nicholson
authors.forename: S J
authors.initials: SJ
authors.lastname: McPherson
authors.forename: R A
authors.initials: RA
authors.lastname: Morgan
authors.forename: A-M
authors.initials: AM
authors.lastname: Belli
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000175:diagnosis / Q000628:therapy*; D000792:Angiography; D021721:Balloon Occlusion; D016461:Chemoembolization, Therapeutic; D004386:Duodenum / Q000098:blood supply; D005260:Female; D006499:Hepatic Artery / Q000473:pathology / Q000601:surgery*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D017538:Mesenteric Artery, Superior / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D010179:Pancreas / Q000098:blood supply; D011145:Polyvinyls / Q000627:therapeutic use*; D012077:Renal Artery / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler; D014656:Vascular Surgical Procedures
chemical_list: D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer