title: Serum lipid levels at 28-32 weeks gestation and hypertensive disorders.
abstract: BACKGROUND
  The etiology and pathogenesis of hypertensive disorders complicating pregnancy are poorly understood, and the definition of these disorders is controversial.
  
  
  METHODS
  In a prospective study, 470 primigravida women between 28 and 32 weeks of pregnancy were evaluated for serum levels of total cholesterol, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, and triglyceride. Afterward, they were observed for any symptoms of preeclampsia and gestational hypertension until 40 weeks of gestational age. We than compared the serum lipid levels among women with preeclampsia and gestational hypertension with those of matched women with normal pregnancies.
  
  
  RESULTS
  The numbers of patients developing preeclampsia and gestational hypertension were 25 (5.3%) and 32 (6.8%), respectively. At the beginning of the study, the mean values of serum triglyceride levels between women who later experienced preeclampsia or gestational hypertension and those who did not differed significantly (p < 0.0001, p < 0.03).
  
  
  CONCLUSIONS
  Although many cases of gestational hypertension represent latent essential hypertension based on the lipid levels, some of these women display true pregnancy-induced hypertension or nonproteinuric preeclampsia.
authors.affiliation: Faculty of Medical Science, Tarbiat Modarres University, Tehran, IR, Iran. ziaei_99@yahoo.com
authors.forename: Saeideh
authors.initials: S
authors.lastname: Ziaei
authors.forename: Khayyati Motlagh
authors.initials: KM
authors.lastname: Bonab
authors.forename: Anoshirvan
authors.initials: A
authors.lastname: Kazemnejad
mesh_terms: D000328:Adult; D001794:Blood Pressure; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005865:Gestational Age; D006801:Humans; D008055:Lipids / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol