title: [Diagnostic difficulties in mammary gland adenosis. Case report].
abstract: Tumor adenosis represents a rare lesion, which most frequent appears as a palpable mass, with more than the usual dimensions. The paper presents a case of tumor adenosis of the mammary gland of a 16 years girl. Macroscopically, the tumor was well delimited, with gray-white surface and a nodular aspect on section. The tissue was processed by routine technique and stained with hematoxylin-eosine (H&E). There were also performed immunohistochemical (Actin SM, CK, S100) and special stainings (silver impregnation). Microscopically, there were observed several histologic types of adenosis, the most frequent being sclerosing adenosis. Through silver impregnation it was observed that the basement membrane, which surrounded the tubes, was intact. Immunohistochemically, there were evidentiated the epithelial and myoepithelial components of the tubes. The presence of these elements led through the diagnosis of tumor adenosis. The importance of recognition of the tumor adenosis is found in the possibility of wrong interpretation of this with tubular invasive carcinoma, these two entities being often mistaken, mainly at the frozen-section examination.
authors.affiliation: Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Disciplina de Histologie.
authors.forename: Raluca
authors.initials: R
authors.lastname: Balan
authors.forename: Cornelia
authors.initials: C
authors.lastname: Amălinei
authors.forename: Florentina
authors.initials: F
authors.lastname: Pricop
authors.forename: V
authors.initials: V
authors.lastname: Gheorghiţă
authors.forename: Ioana
authors.initials: I
authors.lastname: Pintilie
authors.forename: Luminiţa
authors.initials: L
authors.lastname: Ivan
authors.forename: C
authors.initials: C
authors.lastname: Cotuţiu
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000293:Adolescent; D001943:Breast Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D016622:Silver Staining