title: [Technical evolution of the stent].
abstract: Percutaneous coronary intervention has been hampered by restenosis since its inception. Many research projects including the use of various devices and systemic drug administration have shown disappointing results. Recently, the advent of drug-eluting stents has reduced incidence of restenosis compared with bare metal stents. This article provides an overview of the developments of drug-eluting stents, their clinical impact on the treatment of acute coronary syndrome, and their future perspectives.
authors.affiliation: Division of Cardiology, Mitsui Memorial Hospital.
authors.forename: Kengo
authors.initials: K
authors.lastname: Tanabe
mesh_terms: D000789:Angina, Unstable / Q000628:therapy*; D000818:Animals; D002986:Clinical Trials as Topic; D023903:Coronary Restenosis / Q000517:prevention & control; D016503:Drug Delivery Systems; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D017239:Paclitaxel / Q000008:administration & dosage*; D011379:Prognosis; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D013577:Syndrome
chemical_list: D017239:Paclitaxel; D020123:Sirolimus