title: Evaluation of electroacupuncture on ovariectomized rats: implications of modern scientific mechanisms on acupuncture curing woman perimenopausal syndrome.
abstract: Acupuncture has been used for treatment of female reproductive disorders dated back at least 2000 years. It has been known to promote homeostasis, modulate hormonal disturbance and induce ovulation. While the increasing popularity of acupuncture therapy demands a serious debate about its scientific documentation. This article is intended to present the experimental data about the effects of electroacupuncture at Guanyuan (RN 4), bilateral Zhongji (RN 3), Sanyinjiao (SP 6) and bilateral Zigong (EXCA 1) in the ovariectomized rats. The EA stimulation produced from a Model G6805-H EA apparatus, and the stimulation parameters were frequency of 3Hz and intensity about 1-2mA, which was progressed in recent years by our group, so as to provide preliminary scientific background of acupuncture therapy of female perimenopausal syndrome.
authors.affiliation: Department of Neurobiology and Integrative Medicine, Institute of Acupuncture Research (WHO Collaborating Center for Traditional Medicine), Shanghai Medical College of Fudan University, 138 Yi-Xue-Yuan Road, Shanghai 200032, Shanghai, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.forename: Bo-Ying
authors.initials: BY
authors.lastname: Chen
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D015671:Electroacupuncture / Q000379:methods*; D019317:Evidence-Based Medicine / Q000379:methods; D005260:Female; D006801:Humans; D010052:Ovariectomy; D047648:Perimenopause; D011293:Premenstrual Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D051381:Rats; D017207:Rats, Sprague-Dawley