title: [Hiatus hernia and gastroesophageal reflux disease as a manifestation of a newly revealed hypothyroidism].
abstract: The aim of the study was to reveal hypothyroidism (HT) in patients with hiatus hernia (HH), treated at Russian Centre of Functional Surgical Gastroenterology. The subjects were 64 women: 18--with HH and diffuse or diffuse nodular goiter, 36--with HH, and 10--without endocrine or somatic disease background. The examination included the evaluation of the thyroid and metabolic status, endoscopy, and 24-hour ph-metry. The results show that one of the early signs of HT is HH and gastroesophageal reflux disease. The latter in HT patients is associated with gastrointestinal motor-evacuatory disturbances rather than with acid exposition in the distal esophagus.
authors.forename: L V
authors.initials: LV
authors.lastname: Savina
authors.forename: T M
authors.initials: TM
authors.lastname: Semenikhina
authors.forename: N V
authors.initials: NV
authors.lastname: Korochanskaia
authors.forename: I S
authors.initials: IS
authors.lastname: Klitinskaia
authors.forename: M S
authors.initials: MS
authors.lastname: Iakovenko
mesh_terms: D000328:Adult; D003627:Data Interpretation, Statistical; D004724:Endoscopy; D004941:Esophagitis / Q000150:complications / Q000175:diagnosis; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D006551:Hernia, Hiatal / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged