title: [Sodium transport and its regulation of acutely isolated alveolar type II cells].
abstract: OBJECTIVE
  To observe the sodium current of acutely isolated alveolar type II cells and its regulation.
  
  
  METHODS
  After isolation the AT II cells, the whole cell sodium current were recorded in 5 hours with patch-clamp in whole-cell mode, and the effect of amiloride and terbutaline on the current was investigated.
  
  
  RESULTS
  The amiloride-sensitive current of AT II cells were recorded, which could be obviously stimulated by terbutaline.
  
  
  CONCLUSIONS
  Acutely isolated AT II cells can be valuable for studying electrophysiological characteristics of sodium channels even under pathological conditions.
authors.affiliation: Department of Respiratory Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Shen
authors.forename: Tao-ping
authors.initials: TP
authors.lastname: Li
mesh_terms: D000584:Amiloride / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport; D002469:Cell Separation; D018408:Patch-Clamp Techniques; D011650:Pulmonary Alveoli / Q000166:cytology* / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012964:Sodium / Q000378:metabolism*; D026941:Sodium Channel Blockers / Q000494:pharmacology; D015222:Sodium Channels / Q000378:metabolism* / Q000502:physiology; D013726:Terbutaline / Q000494:pharmacology
chemical_list: D026941:Sodium Channel Blockers; D015222:Sodium Channels; D000584:Amiloride; D012964:Sodium; D013726:Terbutaline