[Turner's syndrome, diagnosis and therapeutical approach].
Turner's Syndrome is a rare chromosomal disorder of females (1 : 2500) characterized by short stature and the lack of sexual development at puberty. Other physical features may include a webbed neck, heart defects, kidney abnormalities, and/or various other malformations. Diagnosis should be considered in individuals with primary or secondary amenorrhea and adult women with unexplained infertility, particularly when such individuals also are short in stature. In childhood, growth hormone therapy is standard to prevent short stature as an adult. Estrogen replacement therapy usually is required, but starting too early can compromise adult height. The most frequent, the possibility of a good diagnosis appears at puberty. The early diagnosis needs the karyotyping as screening method. The correct treatment, which is made on time, has a good mental and social life influence.
Moraru
Evelina
E
Universitatea de Medicină şi Farmacie Gr T Popa Iaşi, Facultatea de Medicină, Spitalul de Pediatrie Sf Maria Iaşi, Clinica II Pediatrie.
Dumitrache
C
C
Rusu
Tania
T
Damian
Aurelia
A
Rusu
Cristina
C
Cernescu
Ioana
I
Olinic
Ana
A
D000293:Adolescent; D041321:Chromosomes, Human, X; D003937:Diagnosis, Differential; D005260:Female; D019382:Human Growth Hormone / Q000008:administration & dosage; D006801:Humans; D007621:Karyotyping; D014424:Turner Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics
D019382:Human Growth Hormone