title: Post-operative infection by pathogenic micro-organisms in the oral cavity of patients with prostatic carcinoma.
abstract: The aim of this study was to analyse the change in the oral cavity microflora of 14 patients who had undergone a radical prostatectomy for prostatic carcinoma. The detection of micro-organisms in the oral cavity was compared before and after the surgical procedure. Post-operative infection, defined as those patients who had increased Candida species counts and/or pathogenic bacteria only at the post-operative examination, was observed in 10 patients. Six patients showed increased Candida species counts at the post-operative examination compared with the pre-operative examination. In five patients, pathogenic bacterial species were detected at the post-operative examination but not at the pre-operative examination. One patient had detectable pathogenic bacterial species only at the post-operative examination along with increased Candida species counts. Our findings suggest that pre-operative oral hygiene to remove bacterial and Candida species from patients who are scheduled for surgical procedures is important for satisfactory clinical outcomes.
authors.affiliation: Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan. hsenpuku@nih.go.jp
authors.forename: H
authors.initials: H
authors.lastname: Senpuku
authors.forename: A
authors.initials: A
authors.lastname: Tada
authors.forename: S
authors.initials: S
authors.lastname: Uehara
authors.forename: R
authors.initials: R
authors.lastname: Kariyama
authors.forename: H
authors.initials: H
authors.lastname: Kumon
mesh_terms: D000368:Aged; D002175:Candida / Q000302:isolation & purification; D002180:Candidiasis, Oral / Q000150:complications / Q000382:microbiology; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D006090:Gram-Negative Bacteria / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D007239:Infections / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D011183:Postoperative Complications / Q000382:microbiology; D011184:Postoperative Period; D011468:Prostatectomy / Q000009:adverse effects* / Q000379:methods; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*