No association between GB virus C infection and disease progression in HIV-2-infected patients from the French ANRS HIV-2 cohort.
Out of 183 HIV-2-infected patients tested in the ANRS CO8 HIV-2 cohort, 69 were exposed to GB virus C (GBV-C), yielding a prevalence of 38% (95% CI 30.7, 45.2). There was no significant difference between the CD4 cell count and HIV-2-RNA plasma viral load in patients exposed and not exposed to GBV-C. After adjusting for age and CD4 cell count, co-infection with GBV-C was not associated with clinical progression (hazard ratio 0.78; 95% CI 0.24-2.56, 16 clinical events).
Descamps
Diane
D
Hôpital Bichat-Claude Bernard, Paris, France.
Damond
Florence
F
Bénard
Antoine
A
Matheron
Sophie
S
Campa
Pauline
P
Taieb
Audrey
A
Yahyaoui
Réda
R
Chêne
Geneviève
G
Brun-Vézinet
Françoise
F
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D018791:CD4 Lymphocyte Count; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D018178:Flaviviridae Infections / Q000150:complications* / Q000453:epidemiology / Q000821:virology; D005602:France / Q000453:epidemiology; D029407:GB virus C; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000821:virology; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D008297:Male; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D019562:Viral Load
D000914:Antibodies, Viral; D012367:RNA, Viral