Hepatitis B surface antibody response of household contacts of hepatitis B virus carriers in Palestine.
To evaluate the effectiveness of hepatitis B virus (HBV) vaccination of household contacts of HBV carriers in Tulkarm district, Palestine, quantitative hepatitis B surface (anti-HBs) antibody response in 161 household contacts was measured after vaccination. A seroprotective anti-HBs response (titre > or = 10 IU/L) was elicited in all vaccinated subjects. Of these 2.5% had titres of 10-99 IU/L, 61.5% 100-999 IU/L and 36.0% > or = 1000 IU/L. The number of vaccination doses had no effect on the achievement of seroprotection. HBV infection was demonstrated in 13 cases and their anti-HBV titres were in the range 25-350 IU/L.
Adwan
K
K
Department of Biological Sciences, An-Najah Nablus University, Nablus, Palestine adwank@yahoo.com
Abu-Hasan
N
N
Adwan
G
G
Abu-Khater
K
K
D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing; D019353:Endemic Diseases / Q000517:prevention & control / Q000706:statistics & numerical data; D005191:Family Characteristics; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood*; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D017589:Immunization Programs / Q000458:organization & administration*; D007115:Immunization Schedule; D008297:Male; D037141:Mandatory Programs / Q000458:organization & administration*; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D018579:Patient Selection; D015397:Program Evaluation; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014611:Vaccination / Q000379:methods* / Q000706:statistics & numerical data*
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines