title: [Neuromodulatory effects of bromazepam when individuals were exposed to a motor learning task: quantitative electroencephalography (qEEG)].
abstract: The sedative effects of bromazepam on cognitive and performance have been widely investigated. A number of different approaches have assessed the influence of bromazepam when individuals are engaged to a motor task. In this context, the present study aimed to investigate electrophysiological changes when individuals were exposed to a typewriting task after taking 6 mg of bromazepam. qEEG data were simultaneously recorded during the task. In particular, relative power in delta band (0.5-3.5 Hz) was analyzed. Time of execution and errors during the task were registered as behavioral variables. The experimental group, bromazepam 6 mg, showed a better motor performance and higher relative power than control individuals (placebo). These results suggest that the use of bromazepam reduces anxiety levels as expected and thus, produces an increment in motor performance.
authors.affiliation: Laboratório de Mapeamento Cerebral e Integração Sensório-Motora, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: José Inácio
authors.initials: JI
authors.lastname: Salles
authors.forename: Victor Hugo
authors.initials: VH
authors.lastname: Bastos
authors.forename: Marlo
authors.initials: M
authors.lastname: Cunha
authors.forename: Dionis
authors.initials: D
authors.lastname: Machado
authors.forename: Maurício
authors.initials: M
authors.lastname: Cagy
authors.forename: Vernon
authors.initials: V
authors.lastname: Furtado
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Basile
authors.forename: Roberto
authors.initials: R
authors.lastname: Piedade
authors.forename: Pedro
authors.initials: P
authors.lastname: Ribeiro
mesh_terms: D000513:Alpha Rhythm; D000704:Analysis of Variance; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001960:Bromazepam / Q000494:pharmacology*; D016022:Case-Control Studies; D004594:Electrophysiology; D006801:Humans; D007858:Learning / Q000187:drug effects*; D009048:Motor Skills / Q000187:drug effects* / Q000502:physiology; D011597:Psychomotor Performance / Q000187:drug effects* / Q000502:physiology
chemical_list: D014151:Anti-Anxiety Agents; D001960:Bromazepam