title: Vocal cord paralysis after aortic arch surgery: predictors and clinical outcome.
abstract: OBJECTIVE
  This study is retrospective cohort study of data on vocal cord paralysis after aortic arch surgery collected during 14 years at a general hospital. We investigated factors in the development of vocal cord paralysis after aortic arch surgery and the effect of vocal cord paralysis on clinical course and outcome.
  
  
  METHODS
  We reviewed data for 182 patients who underwent aortic arch surgery for aortic arch aneurysm and aortic dissection between 1989 and 2003, of whom 58 patients had proximal aortic repair, 62 had distal arch repair, and 62 had total arch repair. We assessed factors associated with the development of vocal cord paralysis and examined in detail the clinical outcome of patients with vocal cord paralysis.
  
  
  RESULTS
  Postoperative vocal cord paralysis occurred in 40 patients. Multiple logistic regression analysis revealed the following risk factors with odds ratios (OR) for vocal cord paralysis: extension of procedures into distal arch (OR, 17.0), chronic dilatation of the aorta at the left subclavian artery (OR, 9.14), and total arch repair (OR, 4.24). Adoption of open-style stent-grafts reduced the incidence of vocal cord paralysis (OR, 0.031). The postoperative occurrence of vocal cord paralysis itself emerges as an independent predictor of pulmonary complications (OR, 4.12) and leads to a longer duration of hospital stay.
  
  
  CONCLUSIONS
  The risk of vocal cord paralysis after aortic arch surgery depends on surgical factors, such as aneurysmal involvement of the distal arch, or the application of newer, less invasive surgical procedures. Vocal cord paralysis after aortic arch surgery itself, under aggressive postoperative respiratory management, did not increase aspiration pneumonia but was associated with postoperative complications leading to higher hospital mortality and prolonged hospitalization.
authors.affiliation: Department of Anesthesiology, Osaka General Medical Center, Japan. nohta753@hp-icu.med.osaka-u.ac.jp
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ohta
authors.forename: Toru
authors.initials: T
authors.lastname: Kuratani
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hagihira
authors.forename: Ken-Ichiro
authors.initials: K
authors.lastname: Kazumi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kaneko
authors.forename: Takahiko
authors.initials: T
authors.lastname: Mori
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001013:Aorta, Thoracic / Q000503:physiopathology / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011182:Postoperative Care; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology; D011300:Preoperative Care; D011336:Probability; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D017678:Sex Distribution; D014656:Vascular Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D014826:Vocal Cord Paralysis / Q000453:epidemiology* / Q000209:etiology*