Organelles on the move: insights from yeast vacuole inheritance.
Organelle inheritance is one of several processes that occur during cell division. Recent studies on yeast vacuole inheritance have indicated rules that probably apply to most organelle-inheritance pathways. They have uncovered a molecular mechanism for membrane-cargo transport that is partially conserved from yeast to humans. They have also shown that the transport complex, which is composed of a molecular motor and its receptor, regulates the destination and timing of vacuole movement and might coordinate organelle movement with several other organelle functions.
Weisman
Lois S
LS
Department of Cell and Developmental Biology and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA. lweisman@umich.edu
D002453:Cell Cycle / Q000502:physiology*; D008954:Models, Biological; D008958:Models, Molecular; D020409:Molecular Motor Proteins / Q000502:physiology; D015388:Organelles / Q000235:genetics / Q000502:physiology*; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D014617:Vacuoles / Q000235:genetics / Q000502:physiology*
D020409:Molecular Motor Proteins; D029701:Saccharomyces cerevisiae Proteins