A founder effect and mutational hot spots may contribute to the most frequent mutations in the SPG3A gene.
Namekawa
Michito
M
Nelson
Isabelle
I
Ribai
Pascale
P
Dürr
Alexandra
A
Denis
Elodie
E
Stevanin
Giovanni
G
Ruberg
Merle
M
Brice
Alexis
A
D018703:Founder Effect; D020558:GTP Phosphohydrolases / Q000235:genetics*; D019204:GTP-Binding Proteins; D006239:Haplotypes; D006801:Humans; D008565:Membrane Proteins; D009154:Mutation; D015419:Spastic Paraplegia, Hereditary / Q000235:genetics
D008565:Membrane Proteins; C440006:ATL1 protein, human; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins