Molecular characterization and drug resistance testing of Mycobacterium tuberculosis isolates from Chad.
The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodrug resistance. In total, 9/33 (27%) isolates were resistant to isoniazid. The implications of these findings are discussed.
Diguimbaye
Colette
C
Swiss Tropical Institute, Socinstrasse 57, P.O. Box CH 4002, Basel, Switzerland.
Hilty
Markus
M
Ngandolo
Richard
R
Mahamat
Hassane H
HH
Pfyffer
Gaby E
GE
Baggi
Franca
F
Tanner
Marcel
M
Schelling
Esther
E
Zinsstag
Jakob
J
D000995:Antitubercular Agents / Q000494:pharmacology*; D002596:Chad / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D000995:Antitubercular Agents; D007538:Isoniazid