title: A polymorphism of the interleukin 1 receptor antagonist is not associated with polycystic ovary syndrome in Caucasian women.
abstract: In a prospective case-control study we investigated the association of a common polymorphism of the interleukin 1 receptor antagonist gene (IL-1 RA) with the occurrence and the clinical characteristics of polycystic ovary syndrome (PCOS). Allele frequencies did not vary statistically significantly among women with PCOS and healthy controls or within the PCOS group with respect to their clinical characteristics.
authors.affiliation: Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria. andrea.kolbus@meduniwien.ac.at
authors.forename: Andrea
authors.initials: A
authors.lastname: Kolbus
authors.forename: Katharina
authors.initials: K
authors.lastname: Walch
authors.forename: Laszlo
authors.initials: L
authors.lastname: Szabo
authors.forename: Johannes C
authors.initials: JC
authors.lastname: Huber
authors.forename: Friedrich
authors.initials: F
authors.lastname: Nagele
authors.forename: Gertrud
authors.initials: G
authors.lastname: Unfried
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D011085:Polycystic Ovary Syndrome / Q000235:genetics*; D011110:Polymorphism, Genetic; D011446:Prospective Studies; D012795:Sialoglycoproteins / Q000235:genetics*; D044465:White People / Q000235:genetics*
chemical_list: C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D012795:Sialoglycoproteins