Changes in forearm reciprocal inhibition following pallidal stimulation for dystonia.
The authors recorded forearm H reflex reciprocal inhibition and clinical outcome in eight patients with primary torsion dystonia before and 1, 3, and 6 months after pallidal deep brain stimulation (DBS). There was progressive increase in reciprocal inhibition after surgery, which correlated with clinical improvement. The authors conclude that pallidal DBS for dystonia results in functional reorganization of the nervous system, which includes a long-term increase in spinal inhibition.
Tisch
S
S
obell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square London, United Kingdom.
Limousin
P
P
Rothwell
J C
JC
Asselman
P
P
Zrinzo
L
L
Jahanshahi
M
M
Bhatia
K P
KP
Hariz
M I
MI
D000328:Adult; D020821:Dystonic Disorders / Q000503:physiopathology* / Q000601:surgery; D004558:Electric Stimulation; D005260:Female; D005542:Forearm / Q000294:innervation*; D005917:Globus Pallidus / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time