Bioartificial bone grafting: Tarsal joint fusion in a dog using a bioartificial composite bone graft consisting of beta-tricalciumphosphate and platelet rich plasma--a case report.
Grafting of large bone defects caused by trauma or tumor resection still remains a problem to solve. In experimental studies as well as in human dentistry, osteoconduction and biodegradation of the beta-tricalciumphosphate Cerasorb as well as osteoinductive capabilities of platelet rich plasma have been proven. In case of luxation of the right tarsal joint, including a compressive fracture of the forth tarsal bone, the recommended use of autologous cancellous bone to support osseous fusion was replaced by the use of a bioartificial bone graft. Biodegradation of the bone graft was proven clinically and radiographically. Complete osseous fusion of the intertarsal joint occurred. The use of the beta-tricalciumphosphate Cerasorb in combination with platelet rich plasma to support a partial arthrodesis of the tarsal joint in a dog did not impede the healing process but led to full recovery of the patient, indicating that this concept of bioartificial bone grafting could support bone healing.
Hauschild
G
G
Department of Thorax-, Heart- and Vessel-Surgery, Hannover Medical School, Hannover, Germany. Gregor.Hauschild@tiho-hannover.de
Merten
H A
HA
Bader
A
A
Uhr
G
G
Deivick
A
A
MeyeLindenberg
A
A
Fehr
M
M
D000818:Animals; D001792:Blood Platelets; D001860:Bone Plates / Q000662:veterinary; D018786:Bone Substitutes / Q000008:administration & dosage*; D016025:Bone Transplantation / Q000662:veterinary; D002130:Calcium Phosphates / Q000008:administration & dosage; D004285:Dogs / Q000293:injuries* / Q000601:surgery; D005260:Female; D007593:Joint Instability / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D011859:Radiography; D013643:Tarsus, Animal / Q000000981:diagnostic imaging / Q000293:injuries* / Q000601:surgery*
D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate