title: Flavones with free radical scavenging activity from Goniothalamus tenuifolius.
abstract: From the leaves of Goniothalamus tenuifolius, a new natural product namely 3'-hydroxy-3,5,7,4'-tetramethoxyflavone (1) was isolated, along with seven other known compounds (2-8). Each of these isolates was evaluated for free radical scavenging activity on the DPPH decoloration test. The data obtained in this study suggested that the ortho 3',4'-diphenolic structure was essential for the activity of these flavonol derivatives.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. Kittisak.L@chula.ac.th
authors.forename: Kittisak
authors.initials: K
authors.lastname: Likhitwitayawuid
authors.forename: Chaweewan
authors.initials: C
authors.lastname: Klongsiriwet
authors.forename: Vichien
authors.initials: V
authors.lastname: Jongbunprasert
authors.forename: Boonchoo
authors.initials: B
authors.lastname: Sritularak
authors.forename: Samphan
authors.initials: S
authors.lastname: Wongseripipatana
mesh_terms: D029061:Annonaceae / Q000737:chemistry*; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D047309:Flavones; D016166:Free Radical Scavengers