title: [Analysis of HLA-DRB1 allele polymorphism in the Fujian Han nationality population of China].
abstract: OBJECTIVE
  To investigate the HLA-DRB1 allele polymorphism in Fujian Han nationality population.
  
  
  METHODS
  Six hundred and twenty individual samples collected from unrelated Fujian Han population were subjected to genotyping using oligonucleotide microarray technique. And the allele frequencies of HLA-DRB1 were calculated and compared with other populations.
  
  
  RESULTS
  Fourteen HLA-DRB1 alleles of Fujian Han population were detected. The gene frequencies ordered from high to low were HLA-DRB1*9, 12, 15, 4, 8 respectively.
  
  
  CONCLUSIONS
  The HLA-DRB1 distribution of Fujian Han population shares some genetic characters with southern Chinese Han populations, but these characters differ from northern Chinese populations.
authors.affiliation: Department of Urology, Fuzhou General Hospital, Nanjing Command of PLA, Fuzhou, Fujian, 350025 P.R.China.
authors.forename: Qing-hua
authors.initials: QH
authors.lastname: Wang
authors.forename: Wei-zhen
authors.initials: WZ
authors.lastname: Chen
authors.forename: Jian-ming
authors.initials: JM
authors.lastname: Tan
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005006:Ethnicity; D005787:Gene Frequency / Q000235:genetics*; D005828:Genetics, Population; D005843:Geography; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D011110:Polymorphism, Genetic; D044382:Population Groups
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains