[Visual evoked potentials in children cured with sodium-calcium versenate because of high blood lead level--the prospective study].
OBJECTIVE
To find out if blood lead level (Pb-B) changes have influence on visual evoked potentials.


METHODS
18 children (36 eyes) treated with CaNa2EDTA because of chronic environmental lead poisoning were examined two times: first at age 2-15.5 (mean 8) years and second 4 years later. For pattern VEP LKC equipment, UTAS E-2000 program and stimulations of 13', 26', 52', 105' were used. P100 amplitude and latency were calculated.


RESULTS
Pb-B was decreased from 150-486 (mean 262) microg/l to 42-248 (mean 103) microg/l. After 4 years, P100 latency was significantly delayed in children with Pb-B above 100 microg/l at second examination. In children with Pb-B below 100 microg/l no significant differences between two consecutive examinations were observed. There were no significant differences in P100 amplitude.


CONCLUSIONS
Delayed P100 latency of PVEP in children is permanent but non-progressive if Pb-B is lower than 100 microg/l.
Pojda-Wilczek
Dorota
D
Z Katedry i Oddziału Klinicznego Okulistyki Slaskiej Akademii Medycznej Szpital Specjalistyczny nr 1 w Bytomiu.
Herba
Ewa
E
Schneiberg
Barbara
B
D000293:Adolescent; D002614:Chelating Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004492:Edetic Acid / Q000627:therapeutic use*; D004781:Environmental Exposure; D005074:Evoked Potentials, Visual / Q000187:drug effects*; D005260:Female; D006801:Humans; D007854:Lead / Q000097:blood*; D007855:Lead Poisoning / Q000150:complications / Q000188:drug therapy*; D008297:Male; D011446:Prospective Studies; D012720:Severity of Illness Index; D014786:Vision Disorders / Q000139:chemically induced / Q000175:diagnosis
D002614:Chelating Agents; D007854:Lead; D004492:Edetic Acid