title: First-trimester screening: lessons from clinical trials and implementation.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Koos
mesh_terms: D000328:Adult; D000649:Amniocentesis; D015415:Biomarkers / Q000097:blood; D004314:Down Syndrome / Q000097:blood / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D009436:Neural Tube Defects / Q000097:blood / Q000000981:diagnostic imaging; D048208:Nuchal Translucency Measurement / Q000379:methods; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000097:blood / Q000235:genetics; D016216:Ultrasonography, Prenatal
chemical_list: D015415:Biomarkers