title: Analysis of clinical signs associated with bovine spongiform encephalopathy in casualty slaughter cattle.
abstract: Clinical signs associated with bovine spongiform encephalopathy (BSE) were studied in 1008 casualty slaughter cattle over 30 months of age to compare the results with the BSE status as determined by postmortem tests. The clinical BSE status was assessed using seven different criteria based on various publications. Only one (0.10%) out of 997 casualty slaughter cattle with a matching postmortem test result was positive for BSE. The BSE case was identified by only two case definitions tailored specifically to recumbent cases. The variety and often equivocal definition of clinical signs associated with BSE is reflected by the difference in the criteria that usually identified different animals as BSE suspects. The BSE status may be more difficult to assess in recumbent animals that do not allow a full clinical examination, and BSE may not be suspected if another disease is present that may mask signs of BSE.
authors.affiliation: Neuropathology, VLA Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK. t.konold@vla.defra.gsi.gov.uk
authors.forename: Timm
authors.initials: T
authors.lastname: Konold
authors.forename: S K
authors.initials: SK
authors.lastname: Sivam
authors.forename: Judi
authors.initials: J
authors.lastname: Ryan
authors.forename: Simon
authors.initials: S
authors.lastname: Gubbins
authors.forename: Richard
authors.initials: R
authors.lastname: Laven
authors.forename: Michael J H
authors.initials: MJ
authors.lastname: Howe
mesh_terms: D000003:Abattoirs; D000818:Animals; D001522:Behavior, Animal; D001530:Belgium; D002417:Cattle; D003937:Diagnosis, Differential; D016643:Encephalopathy, Bovine Spongiform / Q000175:diagnosis* / Q000503:physiopathology*; D005858:Germany; D008124:Locomotion; D010808:Physical Examination; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013557:Switzerland