title: HuCNS-SC (StemCells).
abstract: HuCNS-SC, a proprietary human neural stem cells product, is being developed as a cellular therapy for the potential treatment of Batten disease, one of a group of disorders known as neural ceroid lipofuscinoses (NCL). Developer StemCells is also investigating the therapy for spinal cord injury and other central nervous system disorders, such as demyelinating disease, stroke and Alzheimer's disease. A phase I trial of HuCNS-SC for infantile and late-infantile NCL has been initiated, following the March 2006 U.S. Food and Drug Administration approval of StemCells' investigational new drug application.
authors.affiliation: National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, Singapore. obgpjt@nus.edu.sg
authors.forename: Philippe
authors.initials: P
authors.lastname: Taupin
mesh_terms: D002490:Central Nervous System / Q000166:cytology*; D002648:Child; D002675:Child, Preschool; D017321:Clinical Trials, Phase I as Topic; D006801:Humans; D009472:Neuronal Ceroid-Lipofuscinoses / Q000628:therapy*; D018697:Nootropic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D013234:Stem Cells / Q000166:cytology*
chemical_list: D018697:Nootropic Agents