title: Allele frequencies of 15 autosomal STR loci in the Iraq population with comparisons to other populations from the middle-eastern region.
abstract: Allele frequencies for the 15 autosomal STR loci included in the AmpFlSTR((R)) IdentifilerTM PCR Amplification Kit panel from Applied Biosystems (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, CSF1PO, D19S433, D2S1338, D16S539) and several statistical parameters were estimated from a sample of 103 unrelated individuals, mostly Shia and Sunni Arabs, living in most of central and southern Iraq provinces. We compared the allele frequency spectrum detected in the Iraqi population to allele frequencies from 11 other data sets from published studies of individuals from Turkey, Iraqi-Kurdistan, Saudi Arabia, Arab Emarates, Oman, Iran, Syria, and Jordan. Significant global differences in allele frequencies were detected in 9 of the 11 comparisons following sequential Bonferroni corrections. Comparisons with the two independent panels from Saudi Arabia were not significant after applying Bonferroni corrections, however, low P-values (P<0.05) associated with these two contrasts nonetheless suggested that at least slight genetic differences between populations may exist.
authors.affiliation: Carabinieri Scientific Investigation Department of Rome-Molecular Biology and Genetics Unit, Viale di Tor di Quinto 151, 00191 Rome, Italy. filippobarni@tin.it
authors.forename: Filippo
authors.initials: F
authors.lastname: Barni
authors.forename: Andrea
authors.initials: A
authors.lastname: Berti
authors.forename: Antonio
authors.initials: A
authors.lastname: Pianese
authors.forename: Antonio
authors.initials: A
authors.lastname: Boccellino
authors.forename: Mark P
authors.initials: MP
authors.lastname: Miller
authors.forename: Aldo
authors.initials: A
authors.lastname: Caperna
authors.forename: Giampietro
authors.initials: G
authors.lastname: Lago
mesh_terms: D018912:Arabs / Q000235:genetics*; D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008877:Middle East; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences