title: [Radiosurgery of epidermoid tumors with gamma knife: possiblility of radiosurgical nerve decompression].
abstract: Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery.
authors.affiliation: Department of Neurosurgery, Komaki City Hospital, 1-20 Jobushi, Komaki-city 485-8520, Japan.
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Kida
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshimoto
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Shigeru
authors.initials: S
authors.lastname: Fujitani
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000601:surgery*; D002530:Cerebellopontine Angle; D002648:Child; D019299:Decompression, Surgical / Q000379:methods*; D005083:Exfoliatins; D005260:Female; D005500:Follow-Up Studies; D019569:Hemifacial Spasm / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016634:Radiosurgery / Q000379:methods*; D011879:Radiotherapy Dosage; D016896:Treatment Outcome; D014277:Trigeminal Neuralgia / Q000209:etiology
chemical_list: D005083:Exfoliatins