Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles.
In this study, 18 polymeric single amino acid and dipeptide surfactants are examined, and their performances, in terms of enantioselectivity, are compared for norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, benzoin, benzoin methyl, and benzoin ethyl enantiomers. Several aspects of amino acid-based polymeric surfactants including comparison of single amino acid versus dipeptide, amino acid order, steric effect, and effect of the position of the chiral center of dipeptide surfactants on the chiral selectivity of these optically active compounds are discussed.
Billiot
Fereshteh H
FH
Department of Physical and Life Sciences, Texas A and M University-Corpus Christi, Corpus Christi, TX 78412, USA.
Billiot
Eugene J
EJ
Ng
Yuen Kwun
YK
Warner
Isiah M
IM
D000596:Amino Acids / Q000737:chemistry*; D001573:Benzoin / Q000737:chemistry / Q000302:isolation & purification*; D002752:Chlorthalidone / Q000302:isolation & purification*; D007546:Isoquinolines / Q000302:isolation & purification*; D008823:Micelles; D013237:Stereoisomerism; D013765:Tetrahydropapaveroline / Q000302:isolation & purification*
D000596:Amino Acids; D007546:Isoquinolines; D008823:Micelles; D013765:Tetrahydropapaveroline; C001522:laudanosine; D001573:Benzoin; D002752:Chlorthalidone