Fibrillary glomerulonephritis in a patient with type 2 diabetes mellitus.
We report a 62-year-old man with documented type 2 diabetes mellitus and hypertension, who presented with a rapid deterioration in renal function. The sudden decrease in renal function in this well-controlled diabetic patient prompted us to consider a nondiabetic and nonhypertensive cause. The urinary sediment showed a glomerular haematuria suggestive of glomerulonephritis. A diagnosis of fibrillary glomerulonephritis was made on renal biopsy. Fibrillary glomerulonephritis is a rarely diagnosed disease with clinical manifestations such as proteinuria, microscopic haematuria, nephrotic syndrome and impairment of renal function. A diagnosis of fibrillary glomerulonephritis can only be made by electronmicroscopy of the renal tissue. In this case report the spectrum of this disease is reviewed.
Gielen
G A L
GA
Department of Internal Medicine, Slingeland Hospital, Doetinchem, The Netherlands.
Wetzels
J F M
JF
Steenbergen
E J
EJ
Mudde
A H
AH
D001706:Biopsy; D000075202:Contraindications; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use
D011241:Prednisone