title: Copper-catalyzed cycloisomerizations of 5-en-1-yn-3-ols.
abstract: [reaction: see text] The Cu(I)-catalyzed cycloisomerization of tertiary 5-en-1-yn-3-ols with an 1,2-alkyl shift affords stereoselectively tri- and tetracyclic compounds of high molecular complexity. These results are in agreement with a mechanism in which the cyclopropanation precedes the rearrangement.
authors.affiliation: Firmenich SA, Corporate R&D Division, P.O. Box 239, CH-1211 Geneva, Switzerland. charles.fehr@firmenich.com
authors.forename: Charles
authors.initials: C
authors.lastname: Fehr
authors.forename: Iris
authors.initials: I
authors.lastname: Farris
authors.forename: Horst
authors.initials: H
authors.lastname: Sommer