title: [Effect of cigarette smoking on bone quality parameters in women].
abstract: BACKGROUND
  Smoking is a risk factor for osteoporosis. In a previous study, the authors showed lower bone density among smokers in a group of postmenopausal women.
  
  
  OBJECTIVE
  After this finding, the primary goal of current research was to investigate how smoking could influence bone quality.
  
  
  METHODS
  Forty-five (age range: 25-72 ys) smoker women were compared with 45 nonsmoker women adjusted for age and anthropometric parameters. Quantitative ultrasound method was used to determine the speed of ultrasound and the ultrasound attenuation transmitting the left heel (Achilles In Sight, GE Lunar). Dual photon absorptiometry method was applied to investigate the bone mineral density of lumbar spine and left femoral neck (Prodigy, GE Lunar) and single photon absorptiometry was used to determine the bone mineral content of radius at the non dominant side (NK-364, Gamma).
  
  
  RESULTS
  No difference was found between smokers and non-smokers among the premenopausal group, however, postmenopausal smoker women had slightly lower speed of ultrasound and ultrasound attenuation values than non-smoker women. Postmenopausal smoker women suffering from bone fracture had significantly lower speed of ultrasound than postmenopausal non-smoker women (1508.9 vs. 1525.3 m/s, respectively), despite their bone density did not differ from each other.
  
  
  CONCLUSIONS
  These data augment the knowledge about the injurious effect of smoking. The increased risk for bone fracture among smokers could be explained not only with the decrease of bone mass, which was previously described, but also with a decreased bone elasticity.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar, I. Belgyógyászati Klinika, Budapest. meszil@bel1.sote.hu
authors.forename: Szilvia
authors.initials: S
authors.lastname: Mészáros
authors.forename: Viktória
authors.initials: V
authors.lastname: Ferencz
authors.forename: Mónika
authors.initials: M
authors.lastname: Deli
authors.forename: Emoke
authors.initials: E
authors.lastname: Csupor
authors.forename: Edit
authors.initials: E
authors.lastname: Tóth
authors.forename: Csaba
authors.initials: C
authors.lastname: Horváth
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000378:metabolism; D015519:Bone Density; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism*; D005260:Female; D005272:Femur Neck; D050723:Fractures, Bone / Q000209:etiology* / Q000378:metabolism / Q000517:prevention & control; D006801:Humans; D008159:Lumbar Vertebrae; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000209:etiology; D011877:Radionuclide Imaging; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000378:metabolism; D014463:Ultrasonography
chemical_list: D015415:Biomarkers