title: Treatment of recurrent epistaxis in HHT.
abstract: No optimal treatment modality is currently available for the treatment of recurrent epistaxis in HHT. In this review, different therapeutic concepts are discussed together with their pathophysiologic background. Patients often profess a preventive effect for nasal ointments and use packings which can be self-administered in the case of bleeding. An effective first-line treatment for physicians is the endonasal laser coagulation or argon plasma coagulation. A second line surgical procedure is septodermoplasty according to Saunders which can provide long-lasting relief if performed correctly. There have been reports on antifibrinolytic agents and hormones, but their efficacy has yet to be determined.
authors.affiliation: Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Universitätskliniken des Saarlandes, Homburg/Saar, Germany. urban.geisthoff@uniklinik-saarland.de
authors.forename: U W
authors.initials: UW
authors.lastname: Geisthoff
authors.forename: M L
authors.initials: ML
authors.lastname: Fiorella
authors.forename: R
authors.initials: R
authors.lastname: Fiorella
mesh_terms: D000818:Animals; D004844:Epistaxis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D017075:Laser Coagulation; D008028:Light Coagulation; D012008:Recurrence; D012039:Regional Blood Flow / Q000502:physiology; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000503:physiopathology