title: Measurement of cardiac ventricular volumes using multidetector row computed tomography: comparison of two- and three-dimensional methods.
abstract: This study compared a three-dimensional volumetric threshold-based method to a two-dimensional Simpson's rule based short-axis multiplanar method for measuring right (RV) and left ventricular (LV) volumes, stroke volumes, and ejection fraction using electrocardiography-gated multidetector computed tomography (MDCT) data sets. End-diastolic volume (EDV) and end-systolic volume (ESV) of RV and LV were measured independently and blindly by two observers from contrast-enhanced MDCT images using commercial software in 18 patients. For RV and LV the three-dimensionally calculated EDV and ESV values were smaller than those provided by two-dimensional short axis (10%, 5%, 15% and 26% differences respectively). Agreement between the two methods was found for LV (EDV/ESV: r=0.974/0.910, ICC=0.905/0.890) but not for RV (r=0.882/0.930, ICC=0.663/0.544). Measurement errors were significant only for EDV of LV using the two-dimensional method. Similar reproducibility was found for LV measurements, but the three-dimensional method provided greater reproducibility for RV measurements than the two-dimensional. The threshold value supported three-dimensional method provides reproducible cardiac ventricular volume measurements, comparable to those obtained using the short-axis Simpson based method.
authors.affiliation: Unité d'Imagerie Thoracique et Cardiovasculaire, Hôpital Haut-Lévêque, avenue de Magellan, 33600, Pessac, France. michel.montaudon@chu-bordeaux.fr
authors.forename: M
authors.initials: M
authors.lastname: Montaudon
authors.forename: E
authors.initials: E
authors.lastname: Laffon
authors.forename: P
authors.initials: P
authors.lastname: Berger
authors.forename: O
authors.initials: O
authors.lastname: Corneloup
authors.forename: V
authors.initials: V
authors.lastname: Latrabe
authors.forename: F
authors.initials: F
authors.lastname: Laurent
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002306:Cardiac Volume; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D011857:Radiographic Image Interpretation, Computer-Assisted; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*