title: Potent antibody therapeutics by design.
abstract: Antibodies constitute the most rapidly growing class of human therapeutics and the second largest class of drugs after vaccines. The generation of potent antibody therapeutics, which I review here, is an iterative design process that involves the generation and optimization of antibodies to improve their clinical potential.
authors.affiliation: Department of Antibody Technologies, Seattle Genetics Incorporated, 21823 30th Drive South East, Bothell, Washington 98021, USA. pcarter@seagen.com
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Carter
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000627:therapeutic use*; D015195:Drug Design; D006801:Humans
chemical_list: D000911:Antibodies, Monoclonal