title: A polysaccharide isolated from the medicinal herb Bletilla striata induces endothelial cells proliferation and vascular endothelial growth factor expression in vitro.
abstract: A polysaccharide from the traditional Chinese medicinal herb, Bletilla striata (Thunb.) Reichb. f., was isolated, purified and characterized. It induced the proliferation of human umbilical vascular endothelial cells and the expression of vascular endothelial growth factor up to 156% and 147% of control after 72 h, respectively.
authors.affiliation: State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
authors.forename: Chunming
authors.initials: C
authors.lastname: Wang
authors.forename: Jiantao
authors.initials: J
authors.lastname: Sun
authors.forename: Yi
authors.initials: Y
authors.lastname: Luo
authors.forename: Weihua
authors.initials: W
authors.lastname: Xue
authors.forename: Huajia
authors.initials: H
authors.lastname: Diao
authors.forename: Lei
authors.initials: L
authors.lastname: Dong
authors.forename: Jiangning
authors.initials: J
authors.lastname: Chen
authors.forename: Junfeng
authors.initials: J
authors.lastname: Zhang
mesh_terms: D049109:Cell Proliferation / Q000187:drug effects*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D042783:Endothelial Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D004797:Enzyme-Linked Immunosorbent Assay; D005690:Galactose / Q000032:analysis; D005947:Glucose / Q000032:analysis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008358:Mannose / Q000032:analysis; D015394:Molecular Structure; D029595:Orchidaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D042461:Vascular Endothelial Growth Factor A / Q000096:biosynthesis*; D014994:Xylose / Q000032:analysis
chemical_list: D011134:Polysaccharides; D042461:Vascular Endothelial Growth Factor A; D014994:Xylose; D005947:Glucose; D008358:Mannose; D005690:Galactose