The indications for partial nephrectomy in the treatment of renal cell carcinoma.
Partial nephrectomy is performed more frequently for small, incidentally discovered, low-stage renal tumors. Importantly, one should distinguish the imperative indications for such surgery from the relative and elective indications, while taking contraindications to nephron-sparing surgery into account. The main advantage of partial nephrectomy over radical nephrectomy is the avoidance of renal insufficiency; the major disadvantages include the possibility of local recurrence and perioperative complications. In this article, the literature on nephron-sparing surgery was reviewed in order to put the management of renal cancer into a modern perspective.
Joniau
Steven
S
Department of Urology, University Hospital Gasthuisberg, Leuven, Belgium.
Vander Eeckt
Kathy
K
Van Poppel
Hein
H
D002292:Carcinoma, Renal Cell / Q000150:complications / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000209:etiology; D009392:Nephrectomy / Q000009:adverse effects / Q000379:methods*; D017063:Outcome Assessment, Health Care; D051437:Renal Insufficiency / Q000209:etiology / Q000517:prevention & control