title: Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives.
abstract: Diastereoselective aldol coupling reactions with butane-2,3-diacetal (BDA) protected glyceraldehyde derivatives are reported. Good selectivities of up to 20:1 for the homologated aldol products have been achieved in preparatively useful yields.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW.
authors.forename: Kristian Rahbek
authors.initials: KR
authors.lastname: Knudsen
authors.forename: Antonia F
authors.initials: AF
authors.lastname: Stepan
authors.forename: Patrick
authors.initials: P
authors.lastname: Michel
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
mesh_terms: D000080:Acetals / Q000737:chemistry*; D002384:Catalysis; D005985:Glyceraldehyde / Q000031:analogs & derivatives* / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000080:Acetals; C521723:glyceraldehyde butane-2,3-diacetal; D005985:Glyceraldehyde