Production of [15O]water at low-energy proton cyclotrons.
We report a simple system for producing [15O]H2O from 15N in a nitrogen/hydrogen gas target with recycling of the target nitrogen, allowing production on low-energy proton-only accelerators with minimal consumption of isotopically enriched 15N. The radiolabeled water is separated from the target gas and radiolytically produced ammonia by temporary freezing in a small trap at -40 degrees C.
Powell
J
J
Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
O'Neil
J P
JP
D017357:Cyclotrons; D007553:Isotope Labeling / Q000379:methods*; D009587:Nitrogen Isotopes / Q000737:chemistry; D010104:Oxygen Radioisotopes / Q000737:chemistry*; D049268:Positron-Emission Tomography / Q000379:methods; D014867:Water / Q000737:chemistry
D009587:Nitrogen Isotopes; D010104:Oxygen Radioisotopes; D014867:Water