title: Clear-PEM: a dedicated PET camera for improved breast cancer detection.
abstract: Positron emission mammography (PEM) can offer a non-invasive method for the diagnosis of breast cancer. Metabolic images from PEM using 18F-fluoro-deoxy-glucose, contain unique information not available from conventional morphologic imaging techniques like X-ray radiography. In this work, the concept of Clear-PEM, the system presently developed in the frame of the Crystal Clear Collaboration at CERN, is described. Clear-PEM will be a dedicated scanner, offering better perspectives in terms of position resolution and detection sensitivity.
authors.affiliation: Laboratório de Instrumentação e Física Experimental de Partículas and FCUL, FCTUC, IST, UALG, Av. Elias Garcia 14-1, 1000 Lisboa, Portugal.
authors.forename: M C
authors.initials: MC
authors.lastname: Abreu
authors.forename: P
authors.initials: P
authors.lastname: Almeida
authors.forename: F
authors.initials: F
authors.lastname: Balau
authors.forename: N C
authors.initials: NC
authors.lastname: Ferreira
authors.forename: S
authors.initials: S
authors.lastname: Fetal
authors.forename: F
authors.initials: F
authors.lastname: Fraga
authors.forename: M
authors.initials: M
authors.lastname: Martins
authors.forename: N
authors.initials: N
authors.lastname: Matela
authors.forename: R
authors.initials: R
authors.lastname: Moura
authors.forename: C
authors.initials: C
authors.lastname: Ortigão
authors.forename: L
authors.initials: L
authors.lastname: Peralta
authors.forename: P
authors.initials: P
authors.lastname: Rato
authors.forename: R
authors.initials: R
authors.lastname: Ribeiro
authors.forename: P
authors.initials: P
authors.lastname: Rodrigues
authors.forename: A I
authors.initials: AI
authors.lastname: Santos
authors.forename: A
authors.initials: A
authors.lastname: Trindade
authors.forename: J
authors.initials: J
authors.lastname: Varela
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D019788:Fluorodeoxyglucose F18; D015902:Gamma Cameras; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation* / Q000379:methods; D019047:Phantoms, Imaging; D010865:Pilot Projects; D049268:Positron-Emission Tomography / Q000295:instrumentation* / Q000379:methods; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18