title: Oncologic outcome of parosteal osteosarcoma.
abstract: BACKGROUND
  This retrospective review evaluated the clinical features and surgical outcomes of parosteal osteosarcoma (POS).
  
  
  METHODS
  Nine patients were surgically treated and followed up. Their mean age was 30.8 years. Clinical information and oncologic outcomes of each case were analyzed.
  
  
  RESULTS
  Sites of involvement were all in the femur, and all tumors arose from the metaphyseal area of the distal femur. Biopsies for definite diagnoses were performed in just two of the nine cases. Wide resection was applied for all tumors. Surgical evaluations were a 1-cm-wide procedure in six cases and a 2-cm-wide procedure (or more) in three cases. All patients were found to be continuously disease free during the follow-up period of 115.1 months.
  
  
  CONCLUSIONS
  POS showed characteristic findings on radiographic images. Therefore, wide resection without biopsy could be performed in 77.8% (7/9) of the cases. This procedure may contribute to attaining better limb function, because of preventing contamination of healthy surrounding tissue and minimizing the extent of resection. The safety margin was evaluated as a 1-cm-wide procedure. For the choice of reconstruction, indication of autobone grafting (3/9) or total knee replacement (TKR) (6/9) depended on tumor size, location, and shape. With no adjuvant treatments, all cases have shown good clinical courses during the entire follow-up period of about 10 years.
authors.affiliation: Department of Orthopaedic Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-10-6 Ariake, Tokyo 135-8550, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Hoshi
authors.forename: Seiichi
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Jun
authors.initials: J
authors.lastname: Manabe
authors.forename: Taisuke
authors.initials: T
authors.lastname: Tanizawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Shigemitsu
authors.forename: Naohiro
authors.initials: N
authors.lastname: Izawa
authors.forename: Xuedong
authors.initials: X
authors.lastname: Shi
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Kawaguchi
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005269:Femur; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods*; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome