Xanthoma disseminatum of the central nervous system and cranium.
Xanthoma disseminatum is a rare normolipemic histiocytic disorder of non-Langerhans cell origin. It is a chronic systemic disease with a benign course, characterized by disseminated, yellow-orange-colored papules on the face, flexures, and mucosal membranes. We report 3 patients with xanthoma disseminatum, who presented primarily with central nervous system disease and a multitude of imaging findings throughout the craniospinal axis.
Zak
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Department of Radiology, Wayne State University, Detroit, MI, USA.
Altinok
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Neilsen
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SS
Kish
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KK
D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000175:diagnosis; D001927:Brain Diseases / Q000175:diagnosis*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010294:Parietal Bone