Multifocal PVNS in a child--followed over 25 years.
Pigmented villonodular synovitis (PVNS) is a rare disorder of unknown aetiology, characterised by a destructive fibrohistiocytic proliferation with production of villous and nodular protrusions. The disease is commonly monoarticular, and involves the knee in 80% of cases. Occurrence in a child and involvement of multiple joints are extremely unusual. We present a case of multiple joint PVNS in a patient who first presented at the age of five and was subsequently followed up for over twenty-five years. The literature on the subject is briefly reviewed.
Mukhopadhyay
Kausik
K
Derriford Hospital Radiology, Plymouth, UK. kausik@lycos.co.uk
Smith
M
M
Hughes
P M
PM
D002675:Child, Preschool; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007596:Joints; D008279:Magnetic Resonance Imaging; D013586:Synovitis, Pigmented Villonodular / Q000175:diagnosis* / Q000473:pathology; D013995:Time