title: Cyanide ion cocatalysis in Ti(salen) catalysed asymmetric cyanohydrin carbonate synthesis.
abstract: In the presence of potassium cyanide or the potassium cyanide/18-crown-6 complex as a cocatalyst, 1-2 mol% of titanium(salen) complex catalyses the asymmetric addition of achiral cyanoformates to aldehydes, giving cyanohydrin carbonates with high enantiomeric excesses; and catalyses the diastereoselective addition of chiral cyanoformates derived from alpha-methylbenzyl alcohol to aldehydes, a reaction which exhibits double asymmetric induction.
authors.affiliation: A. N. Nesmeyanov Institute of Organo-Element Compounds, Russian Academy of Sciences, Vavilov 28, Russian Federation.
authors.forename: Yuri N
authors.initials: YN
authors.lastname: Belokon
authors.forename: Eisuke
authors.initials: E
authors.lastname: Ishibashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nomura
authors.forename: Michael
authors.initials: M
authors.lastname: North