Auxiliary partial orthotopic living donor liver transplantation in a patient with alcoholic liver cirrhosis to overcome donor steatosis.
The efficacy of auxiliary partial orthotopic liver transplantation (APOLT) to overcome the problems associated with a markedly steatotic graft in a living donor has not been fully explored. We have recently performed APOLT in a patient with alcoholic liver disease, where the only potential candidate donor was affected by 50% macrovesicular steatosis and 30% microvesicular steatosis. The recipient's left liver was resected and the donor's left liver, corresponding to a 0.46% graft-to-recipient weight ratio, was orthotopically transplanted. The postoperative course of this patient was uneventful, except for a transient large amount of ascites. Native liver volume in the recipient serially decreased, and the volume of the graft serially increased after transplantation. Four months after transplantation, the donor and recipient are doing well with a normal liver function. In conclusion, APOLT may be a feasible solution for a markedly steatotic living donor graft in patients with alcoholic liver disease.
Cho
Jai Young
JY
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Suh
Kyung-Suk
KS
Kwon
Choon Hyuck
CH
Yi
Nam-Joon
NJ
Kim
Min A
MA
Kim
Min Aon
MA
Jang
Ja-June
JJ
Minn
Kyung Won
KW
Lee
Kuhn Uk
KU
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000418:Albumins / Q000096:biosynthesis; D001219:Aspartate Aminotransferases / Q000097:blood; D001646:Bile / Q000378:metabolism; D001663:Bilirubin / Q000097:blood; D005234:Fatty Liver / Q000628:therapy*; D006085:Graft Survival; D006801:Humans; D008099:Liver / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000628:therapy*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged
D000418:Albumins; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin