[Does the hearing loss affect the child's innate immunity?--preliminary].
Human neutrophiles play a crucial role in inmate immunity. Inmate and aquired immune response depend on their functional condition at the first stage of an inflammation process. Reactive forms of oxygen (RFO) produced by neutrophiles play a significant role in the eradication of pathogens as well as in the regulation of immune response. The aim of this study is question, does the hearing loss affect the inmate immunity?


METHODS
The RFO production was directly examined in four systems - without stimulation, after stimulation with fMLP, opsonized zymosan or PMA. Direct RFO measurement was performed chemiluminescency evaluation using the whole blood, which indirectly depend on RFO production.


RESULTS
In the group of children with hearing loss was observed disturbances in RFO productions.


CONCLUSIONS
This observation is very original and important for general practice.
Smiechura
Małgorzata
M
Instytut Centrum Zdrowia Matki Polki w Lodzi, Klinika Otolaryngologii.
Makowski
Andrzej
A
Lewkowicz
Przemysław
P
Tchórzewski
Henryk
H
D006311:Hearing Disorders / Q000453:epidemiology* / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D008163:Luminescent Measurements; D015997:Neonatal Screening / Q000379:methods; D009504:Neutrophils / Q000276:immunology / Q000502:physiology*; D017382:Reactive Oxygen Species; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000276:immunology
D017382:Reactive Oxygen Species