title: Haemophilus Influenzae contributes to morbidity but not mortality in severely burned patients.
abstract: Due to a successful Haemophilus Influenzae (HIF) vaccination program, this pathogen is no longer a major contributor to childhood morbidity and mortality. The effect on adult acquisition of HIF is unknown. The purpose of this study was to determine HIF infection frequency in severely burned patients. In a 62-month period, there were 1486 admissions. Twenty-four of 1,486 (1.6%) burn patients had HIF pneumonia: 16 (1%) within 72 h after injury; 8 (0.5%) patients developed it after the seventh day of hospitalization; 74 of 1,486 (5.0%) burn patients had pneumonia due to other organisms. There was no statistically significant difference between patients with HIF pneumonia and those with other pathogens with respect to age, race, sex, percent total body surface area (TBSA), inhalation injury, ventilator days, intensive care days, sepsis, or mortality. Nineteen percent of patients with HIF were<14 years of age compared to 12% in the other pneumonia group, p<0.01. HIF contributed to both an early and late pneumonia in burn patients. The organism responded to treatment and did not affect mortality.
authors.affiliation: Department of Pediatrics, Hope Children's Hospital, Advocate Christ Medical Center, Oaklawn, IL, USA.
authors.forename: Tamara Z
authors.initials: TZ
authors.lastname: Vern
authors.forename: Areta
authors.initials: A
authors.lastname: Kowal-Vern
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Latenser
authors.forename: Alan
authors.initials: A
authors.lastname: Chakrin
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002053:Burn Units; D002056:Burns / Q000382:microbiology* / Q000401:mortality; D006192:Haemophilus Infections / Q000401:mortality*; D006193:Haemophilus influenzae; D006801:Humans; D018410:Pneumonia, Bacterial / Q000401:mortality; D012189:Retrospective Studies; D012621:Seasons