title: Ewing sarcoma/PNET: 27 years of experience in Slovenia.
abstract: The study includes 91 patients treated for Ewing sarcoma between 1972 and 2002. Forty were younger and 51 were older than 16. The overall 5-year survival was 36%: 53.5% in the younger and 22.5% in the older age group. Among patients with localized disease, 5-year survival was 58% in younger and 25.5% in the older. Survival was similar whether patients received three treatment modalities or chemotherapy combined with either surgery or radiotherapy. Recurrence was noted in 47 out of 75 patients with localized disease, most commonly as local recurrence or lung metastases. Among 18 evaluated patients, 14 had minor physical defects and 4 had severe late treatment effects (sterility in 3 and secondary osteogenic sarcoma in 1).
authors.affiliation: Department of Cytopathology, Institute of Oncology, Ljubljana, Slovenia. zpohar@onko-i.si
authors.forename: Ziva Pohar
authors.initials: ZP
authors.lastname: Marinsek
authors.forename: Rajko
authors.initials: R
authors.lastname: Kavalar
authors.forename: Berta
authors.initials: B
authors.lastname: Jereb
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols; D003131:Combined Modality Therapy; D006801:Humans; D007246:Infertility / Q000209:etiology; D009367:Neoplasm Staging; D012516:Osteosarcoma / Q000209:etiology; D012008:Recurrence; D012512:Sarcoma, Ewing / Q000150:complications / Q000401:mortality / Q000628:therapy; D017524:Slovenia / Q000453:epidemiology; D015996:Survival Rate