title: Carbon dioxide-enhanced sonographically guided radiofrequency ablation plus transcatheter arterial chemoembolization for hepatocellular carcinoma.
abstract: A 78-year-old man had a history of blood transfusion and hepatitis C virus-related liver cirrhosis. He was admitted to the authors' hospital with a hepatocellular carcinoma just below the right hemidiaphragm. Although the lesion was not well visualized with standard sonography, it was clearly defined by performance of sonography with intraarterial injection of carbon dioxide, allowing safe and accurate radiofrequency ablation. To increase the extent of tumor ablation, transcatheter arterial chemoembolization was performed immediately before radiofrequency ablation. By concomitant application of these two techniques, complete tumor necrosis was achieved without the need to perform additional ablation.
authors.affiliation: Division of Hepatology, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan. ohmotok@med.kawasaki-m.ac.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohmoto
authors.forename: Naoko
authors.initials: N
authors.lastname: Yoshioka
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Tomiyama
authors.forename: Norikuni
authors.initials: N
authors.lastname: Shibata
authors.forename: Tomoya
authors.initials: T
authors.lastname: Kawase
authors.forename: Koji
authors.initials: K
authors.lastname: Yoshida
authors.forename: Makoto
authors.initials: M
authors.lastname: Kuboki
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D002245:Carbon Dioxide; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D017115:Catheter Ablation; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008297:Male; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional
chemical_list: D002245:Carbon Dioxide