title: Vaccine-associated paralytic poliomyelitis caused by contact infection.
abstract: We encountered an adult patient with acute anterior poliomyelitis (AAP), whose monoparesis developed 28 days after his son's immunization with oral poliovirus vaccine (OPV). Neurological and electrophysiological examinations suggested that his muscular wasting of the left lower limb was due to a lower motor neuron disorder, and magnetic resonance imaging revealed the responsible lesion in the left anterior horn at the thoracolumbar junction. His stool was found to include poliovirus type 3, mainly originating from Sabin 3 by neutrization antibody and PCR-restriction fragment length polymorphism method. This indicated that the AAP resulted from contact with his son. This patient raises the question about OPV in polio-free countries.
authors.affiliation: Department of Neurology, Ehime Prefectural Central Hospital, Matsuyama.
authors.forename: Bungo
authors.initials: B
authors.lastname: Okuda
authors.forename: Eri
authors.initials: E
authors.lastname: Uetani
authors.forename: Kensho
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000328:Adult; D005243:Feces / Q000821:virology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011051:Poliomyelitis / Q000175:diagnosis / Q000635:transmission*; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects*; D013116:Spinal Cord / Q000473:pathology; D013997:Time Factors
chemical_list: D011055:Poliovirus Vaccine, Oral