title: Enantioselective synthesis mediated by chiral crystal of achiral hippuric acid in conjunction with asymmetric autocatalysis.
abstract: Enantiomorphous crystals composed of achiral hippuric acid, i.e., naturally occurring N-benzoylglycine, have been used successfully as chiral inducers in enantioselective synthesis in combination with asymmetric autocatalysis to afford the product with extremely high enantiomeric excess.
authors.affiliation: Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
authors.forename: Tsuneomi
authors.initials: T
authors.lastname: Kawasaki
authors.forename: Kenta
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Hatase
authors.forename: Masanari
authors.initials: M
authors.lastname: Otsuka
authors.forename: Hideko
authors.initials: H
authors.lastname: Koshima
authors.forename: Kenso
authors.initials: K
authors.lastname: Soai
mesh_terms: D002384:Catalysis; D002942:Circular Dichroism; D003460:Crystallization; D006626:Hippurates / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D006626:Hippurates; C030514:hippuric acid