Cerebral infarction after high-dose intravenous immunoglobulin therapy for Kawasaki disease.
A 3-year-old boy with Kawasaki disease developed a cerebral infarction after high-dose intravenous immunoglobulin. Aspirin did not prevent the stroke. Based on the numerous reports of thrombosis due to high-dose immunoglobulin in older individuals, we conclude that it is necessary to be aware of this complication when treating children with Kawasaki disease.
Wada
Yasunori
Y
Department of Pediatrics, Iwate Medical University School of Medicine, Morioka, Japan.
Kamei
Atsushi
A
Fujii
Yukiharu
Y
Ishikawa
Ken
K
Chida
Shoichi
S
D002544:Cerebral Infarction / Q000139:chemically induced*; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy*
D016756:Immunoglobulins, Intravenous