Review of ocular drug delivery.
Successful treatment of eye diseases requires effective concentration of drug at the eye for sufficient period of time. Conventional ocular drug delivery including eye drops, systemic administration, ophthalmic ointments, is no longer sufficient to combat ocular diseases. This article reviews the constraints with conventional ocular therapy, and explores various novel approaches, to improve the ocular bioavailability of drugs to the anterior chamber of the eye.
Sultana
Yasmin
Y
Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi 110062, India. yas2312003@yahoo.com
Jain
R
R
Aqil
M
M
Ali
Asgar
A
D000818:Animals; D003094:Collagen / Q000008:administration & dosage; D003261:Contact Lenses; D016503:Drug Delivery Systems; D005128:Eye Diseases / Q000188:drug therapy*; D005612:Freeze Drying; D005782:Gels; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008081:Liposomes; D008863:Microspheres; D009824:Ointments; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D013696:Temperature
D005782:Gels; D008081:Liposomes; D009824:Ointments; D009883:Ophthalmic Solutions; D003094:Collagen