title: Unusual course of infective endocarditis: acute renal failure progressing to chronic renal failure.
abstract: Infective endocarditis is an infection of the endocardium that usually involves the valves and adjacent structures. The classical fever of unknown origin presentation represents a minority of infective endocarditis. The presented case was a 21-yearold young lady presenting with acute renal failure and fever to the emergency room. Cardiac auscultation revealed a soft S1 and 4/6 apical holosystolic murmur extended to axilla. Echocardiography showed mobile fresh vegetation under the mitral posterior leaflet. She was diagnosed as having infective endocarditis. Hemodialysis was started with antimicrobial therapy. However, because of the presence of severe mitral regurgitation with left ventricle dilatation and large mobile vegetation, mitral prosthetic mechanical valve replacement was performed. Although treated with antibiotics combined with surgery, renal functions were deteriorated and progressed to chronic renal failure.
authors.affiliation: Department of Internal Medicine, School of Medicine, Sahinbey Medical Center, Gaziantep University, Turkey. sevinc@gantep.edu.tr
authors.forename: Alper
authors.initials: A
authors.lastname: Sevinc
authors.forename: Vedat
authors.initials: V
authors.lastname: Davutoglu
authors.forename: Irfan
authors.initials: I
authors.lastname: Barutcu
authors.forename: M Esra
authors.initials: ME
authors.lastname: Kocoglu
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D018450:Disease Progression; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000601:surgery*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D006435:Renal Dialysis; D013203:Staphylococcal Infections / Q000150:complications*; D013211:Staphylococcus aureus / Q000302:isolation & purification; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000925:Anticoagulants; D014859:Warfarin