title: The effects of free fat graft or cellulose membrane implants on laminectomy membrane formation in dogs.
abstract: The purpose of this study was to determine the effect of cellulose membrane or free fat grafts (FFG) on laminectomy membrane (LM) formation. Eighteen dogs were randomly divided into three groups of six dogs. All dogs underwent a modified dorsal laminectomy on T(13)-L(1). The laminectomy defect was left uncovered in the control group but either a FFG or a cellulose membrane implant was provided in the other two groups. The dogs were evaluated through neurological examination, myelography, macroscopic roundness index of spinal cord and histological evaluations of epidural fibrosis and spinal cord. The results showed a significant difference between the control and the FFG group, with the FFG causing neurological deficits and spinal cord compression as assessed by the roundness index of the spinal cord. Both FFG and cellulose membrane were partially effective in preventing LM formation. The use of FFG was associated with a high rate of significant neurological complications and spinal cord lesions.
authors.affiliation: Department of Veterinary Medicine, Federal University of Paraná, Campus Palotina, Palotina, PR 85950-000, Brazil. rdacosta@uoguelph.ca
authors.forename: Ronaldo C
authors.initials: RC
authors.lastname: da Costa
authors.forename: Ney L
authors.initials: NL
authors.lastname: Pippi
authors.forename: Dominguita L
authors.initials: DL
authors.lastname: Graça
authors.forename: Sérgio A
authors.initials: SA
authors.lastname: Fialho
authors.forename: Aline
authors.initials: A
authors.lastname: Alves
authors.forename: Ana C
authors.initials: AC
authors.lastname: Groff
authors.forename: Ubiratã
authors.initials: U
authors.lastname: Rezler
mesh_terms: D000273:Adipose Tissue; D000818:Animals; D002482:Cellulose; D004283:Dog Diseases / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D007796:Laminectomy / Q000379:methods / Q000662:veterinary*; D009192:Myelography / Q000662:veterinary; D011183:Postoperative Complications / Q000662:veterinary; D019736:Prostheses and Implants / Q000662:veterinary; D011897:Random Allocation; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery; D013117:Spinal Cord Compression / Q000209:etiology / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D013122:Spinal Diseases / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D013526:Surgical Mesh
chemical_list: D002482:Cellulose