title: Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasis.
abstract: Sodium stibogluconate (Pentostam(R); GlaxoSmithKline) is a pentavalent antimonial compound used in the treatment of leishmaniasis, which has an association with reactivation of varicella zoster virus (VZV). We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate.
authors.affiliation: Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA. Joshua.hartzell@na.amedd.army.mil
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Hartzell
authors.forename: Naomi E
authors.initials: NE
authors.lastname: Aronson
authors.forename: Sudhir
authors.initials: S
authors.lastname: Nagaraja
authors.forename: Tim
authors.initials: T
authors.lastname: Whitman
authors.forename: Clifton A
authors.initials: CA
authors.lastname: Hawkes
authors.forename: Glenn
authors.initials: G
authors.lastname: Wortmann
mesh_terms: D000328:Adult; D000818:Animals; D000967:Antimony Sodium Gluconate / Q000009:adverse effects*; D000981:Antiprotozoal Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D020804:Encephalitis, Varicella Zoster / Q000209:etiology*; D006562:Herpes Zoster; D006801:Humans; D018320:Leishmania major / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D017193:Skin Diseases, Viral / Q000209:etiology
chemical_list: D000981:Antiprotozoal Agents; D000967:Antimony Sodium Gluconate