title: Scientific and medical aspects of ozone therapy. State of the art.
abstract: The aim of this review is to dispel misconceptions and skepticism regarding ozone therapy and to clarify the biochemical and pharmacological mechanisms of action of ozone dissolved in biological fluids. The work performed in the last decade in our laboratory allows drawing a comprehensive framework for understanding and recommending ozone therapy in some diseases. It is hoped that this report will open a dialogue among clinical scientists and will inform physicians about the beneficial effects of ozone therapy.
authors.affiliation: Department of Physiology, University of Siena, Siena, Italy. bocci@unisi.it
authors.forename: Velio Alvaro
authors.initials: VA
authors.lastname: Bocci
mesh_terms: D000438:Alcohols / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001826:Body Fluids / Q000737:chemistry / Q000187:drug effects; D006801:Humans; D006931:Hyperbaric Oxygenation; D008054:Lipid Peroxides / Q000737:chemistry / Q000378:metabolism; D010126:Ozone / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D017382:Reactive Oxygen Species / Q000737:chemistry / Q000378:metabolism
chemical_list: D000438:Alcohols; D008054:Lipid Peroxides; D017382:Reactive Oxygen Species; C059688:alkoxyl radical; D010126:Ozone