title: The significance of cutaneous spider naevi in children.
abstract: BACKGROUND
  Cutaneous spider naevi are commonly considered to be a clinical sign of chronic liver disease. Little is known about their occurrence in children.
  
  
  OBJECTIVE
  To evaluate the occurrence of spider naevi in children with and without liver disease.
  
  
  METHODS
  The presence of spider naevi was investigated in 460 children, 34 of whom had chronic liver disease.
  
  
  RESULTS
  Of children without liver involvement, 38% had at least one spider naevus. The prevalence of spider naevi increased with age. Of control patients aged 5 to 15 years, 2.5% had more than five spiders present. Although eight of 10 children with cirrhosis had at least one spider naevus, only four of 34 children with chronic liver disease had five or more spiders present. Most spiders were on the hands and very few were >5 mm in size.
  
  
  CONCLUSIONS
  Children with liver disease rarely have large numbers of spider naevi. Although the finding of five or more spider naevi is more common in liver disease, many normal children also have one or more of these lesions.
authors.affiliation: Children's Research Centre, Our Lady's Hospital, Conway Institute for Biomolecular and Biomedical Research, and Department of Paediatrics, University College Dublin, Ireland.
authors.forename: S M
authors.initials: SM
authors.lastname: Finn
authors.forename: M
authors.initials: M
authors.lastname: Rowland
authors.forename: F
authors.initials: F
authors.lastname: Lawlor
authors.forename: W
authors.initials: W
authors.lastname: Kinsella
authors.forename: L
authors.initials: L
authors.lastname: Chan
authors.forename: O
authors.initials: O
authors.lastname: Byrne
authors.forename: O
authors.initials: O
authors.lastname: O'Mahony
authors.forename: B
authors.initials: B
authors.lastname: Bourke
mesh_terms: D000293:Adolescent; D000367:Age Factors; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007223:Infant; D008107:Liver Diseases / Q000150:complications*; D008297:Male; D009506:Nevus / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology*