[Effects of chromium and fish oil on the level of leptin and insulin in obese rats].
OBJECTIVE
In order to study the effects of chromium and fish oil on the level of leptin and insulin in obese rats, 32 obese model rats were divided randomly into four groups: fish oil group (5 ml/kg bw), chromium group (3 mg/kg bw), fish oil + chromium group and high fat diet group.


METHODS
In the end of the experiment (6 weeks) fats around kidney and spermary were weighted and blood samples were collected to determine the level leptin and insulin.


RESULTS
The results showed that the level of leptin and insulin in experimental groups were lower than those in high fat diet group. The ratios of fats around kidney and/or around spermary to body weight in experimental groups were lower than those in high fat diet group.


CONCLUSIONS
Chromium and fish oil possible depress the high level of leptin and insulin in obese model rats.
Wang
Shu-Ran
SR
School of Public Health, Harbin Medical University, Harbin 150086, China.
Ma
Wei-Wei
WW
Niu
Yu-Cun
YC
Sun
Chang-Hao
CH
D000818:Animals; D002857:Chromium / Q000494:pharmacology*; D005395:Fish Oils / Q000494:pharmacology*; D007328:Insulin / Q000097:blood*; D020738:Leptin / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D005395:Fish Oils; D007328:Insulin; D020738:Leptin; D002857:Chromium