title: Solid-phase synthesis of oligo(p-benzamide) foldamers.
abstract: [reaction: see text] A coupling protocol has been developed which allows the synthesis of oligo(p-benzamide)s on solid support. Aromatic carboxylic acids are activated in situ with thionyl chloride and used to acylate secondary aromatic amines. N-p-Methoxy benzyl (PMB) as well as N-hexyl protected monomers were investigated. Heterosequences of both monomers were synthesized. Such nanoscale objects are important building blocks for supramolecular chemistry.
authors.affiliation: Johannes Gutenberg-Universität Mainz, Institut für Organische Chemie, Duesbergweg 10-14, 55099 Mainz, Germany.
authors.forename: Hannah M
authors.initials: HM
authors.lastname: König
authors.forename: Robert
authors.initials: R
authors.lastname: Abbel
authors.forename: Dieter
authors.initials: D
authors.lastname: Schollmeyer
authors.forename: Andreas F M
authors.initials: AF
authors.lastname: Kilbinger