Histopathologic correlation of dilatation and currettage and hysterectomy specimens in patients with postmenopausal bleeding.
OBJECTIVE
To evaluate the consistency of preoperative and postoperative histopathological findings in postmenopausal patients with abnormal bleeding.


METHODS
Pathologic diagnoses of 42 postmenopausal women with abnormal bleeding or increased endometrial thickness who underwent both dilatation and curettage (D and C), and hysterectomy for proper indications were retrospectively examined.


RESULTS
The most common diagnosis was irregular proliferative endometrium in both the pre- and postoperative groups with 16 patients each (38%). After subgroup analysis, 50% of the patients with a preoperative diagnosis of complex hyperplasia without atypia, had complex atypical hyperplasia, and two-thirds of the patients with a preoperative diagnosis of complex atypical hyperplasia had endometrial cancer as the final diagnoses.


CONCLUSIONS
Preoperative D and C endometrial pathology findings positively correlated with postoperative hysterectomy pathology results. However, as the real pathology gets worse , D and C seems to under-diagnose the real pathology. In cases with complex hyperplasia with or without atypia , a second D and C or hysteroscopic evaluation may be recommended.
Saygili
H
H
Department of Obstetrics and Gynecology, School of Medicine, Istanbul University, Istanbul, Turkey.
D004107:Dilatation and Curettage; D004714:Endometrial Hyperplasia / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D017698:Postmenopause; D014592:Uterine Hemorrhage / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*