Flavones with free radical scavenging activity from Goniothalamus tenuifolius.
From the leaves of Goniothalamus tenuifolius, a new natural product namely 3'-hydroxy-3,5,7,4'-tetramethoxyflavone (1) was isolated, along with seven other known compounds (2-8). Each of these isolates was evaluated for free radical scavenging activity on the DPPH decoloration test. The data obtained in this study suggested that the ortho 3',4'-diphenolic structure was essential for the activity of these flavonol derivatives.
Likhitwitayawuid
Kittisak
K
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. Kittisak.L@chula.ac.th
Klongsiriwet
Chaweewan
C
Jongbunprasert
Vichien
V
Sritularak
Boonchoo
B
Wongseripipatana
Samphan
S
D029061:Annonaceae / Q000737:chemistry*; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D013329:Structure-Activity Relationship
D047309:Flavones; D016166:Free Radical Scavengers