title: Xanthoma disseminatum of the central nervous system and cranium.
abstract: Xanthoma disseminatum is a rare normolipemic histiocytic disorder of non-Langerhans cell origin. It is a chronic systemic disease with a benign course, characterized by disseminated, yellow-orange-colored papules on the face, flexures, and mucosal membranes. We report 3 patients with xanthoma disseminatum, who presented primarily with central nervous system disease and a multitude of imaging findings throughout the craniospinal axis.
authors.affiliation: Department of Radiology, Wayne State University, Detroit, MI, USA.
authors.forename: I T
authors.initials: IT
authors.lastname: Zak
authors.forename: D
authors.initials: D
authors.lastname: Altinok
authors.forename: S S F
authors.initials: SS
authors.lastname: Neilsen
authors.forename: K K
authors.initials: KK
authors.lastname: Kish
mesh_terms: D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000175:diagnosis; D001927:Brain Diseases / Q000175:diagnosis*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010294:Parietal Bone