Resolution of eosinophilia after treatment of cutaneous gnathostomiasis.
The present study was to investigate the dynamics of eosinophil in peripheral blood of patients with cutaneous gnathostomiasis before and after worm removal. The total of 28 proven cases of cutaneous gnathostomiasis treated by albendazole were included in the present study. The absolute eosinophil count (AEC) was higher than 500/ul during infestation in almost all the patients, the positive rate was 89%, and significantly decreased to normal level after receiving albendazole and worm removal within 3 months in 96%. In conclusion, an increas of AEC is another important hallmarks of cutaneous gnathostomiasis and this parameter could be the earlier indicator for responsiveness to treatment.
Kraivichian
Kanyarat
K
Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nuchprayoon
Surang
S
Siriyasatien
Padet
P
Saksirisamphan
Wilai
W
Nuchprayoon
Issarang
I
D000293:Adolescent; D000328:Adult; D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D004802:Eosinophilia / Q000188:drug therapy* / Q000469:parasitology; D005260:Female; D006039:Gnathostoma / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012876:Skin Diseases, Parasitic; D017205:Spirurida Infections / Q000188:drug therapy*; D016896:Treatment Outcome
D000969:Antinematodal Agents; D015766:Albendazole