title: Zaleplon (Sonata) oral sedation for outpatient third molar extraction surgery.
abstract: Zalpelon was compared with triazolam for oral sedation in a third molar surgery model using a double-blind crossover design. Factors such as anxiolysis, amnesia, and quality of sedation were assessed. Of the 14 participants who completed the study, zaleplon sedation was found to be similar to triazolam sedation in all regards except that recovery from zaleplon was more rapid.
authors.affiliation: Department of Dental Anesthesiology, Children's Hospital, Ohio State University College of Dentistry, Columbus, Ohio 43205, USA. ganzbers@chi.osu.edu
authors.forename: Steven I
authors.initials: SI
authors.lastname: Ganzberg
authors.forename: Thomas
authors.initials: T
authors.lastname: Dietrich
authors.forename: Manuel
authors.initials: M
authors.lastname: Valerin
authors.forename: F Michael
authors.initials: FM
authors.lastname: Beck
mesh_terms: D000081:Acetamides / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D000766:Anesthesia, Dental; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D001007:Anxiety / Q000517:prevention & control; D016292:Procedural Sedation; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008297:Male; D008568:Memory / Q000187:drug effects; D008964:Molar, Third / Q000601:surgery*; D011743:Pyrimidines / Q000008:administration & dosage*; D014081:Tooth Extraction; D014229:Triazolam / Q000627:therapeutic use
chemical_list: D000081:Acetamides; D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives; D011743:Pyrimidines; D014229:Triazolam; C085665:zaleplon