Effect of discontinuing of laronidase in a patient with mucopolysaccharidosis type I.
We present a patient on enzyme replacement therapy who showed rapid deterioration when laronidase was discontinued owing to pregnancy.
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Willink Biochemical Genetics Unit Royal Manchester, Children's Hospital, M27 4HA, Manchester, UK.
Mercer
J
J
Wraith
J E
JE
D000328:Adult; D005260:Female; D006801:Humans; D007068:Iduronidase / Q000627:therapeutic use*; D008059:Mucopolysaccharidosis I / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; D007068:Iduronidase