Cutaneous plasmacytosis: A report of five cases with immunohistochemical evaluation for HHV-8 expression.
Cutaneous plasmacytosis is a rare disorder that typically affects middle-aged to older individuals of Asian, particularly Japanese, descent. Clinically, it is characterized by multiple asymptomatic red-brown plaques and nodules on the trunk. Lymphadenopathy and hypergammaglobulinemia may be present. Histologically, the lesions show a moderately dense superficial and deep perivascular infiltrate composed predominantly of mature plasma cells without atypia or light chain restriction. We report our experience with five additional cases, including results of immunohistochemical studies for human herpes virus 8.
Jayaraman
Anu G
AG
Department of Pathology, Stanford University, Stanford, CA 94305-5324, USA.
Cesca
Christine
C
Kohler
Sabine
S
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D019288:Herpesvirus 8, Human / Q000302:isolation & purification*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000276:immunology / Q000473:pathology / Q000821:virology; D010950:Plasma Cells / Q000276:immunology / Q000473:pathology* / Q000821:virology; D012871:Skin Diseases / Q000276:immunology / Q000473:pathology* / Q000821:virology
D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains