title: Rapid conversion of hindered arylsulfonates to alkyl chlorides with retention of configuration.
abstract: Arylsulfonates of hindered secondary alcohols are converted to the corresponding alkyl chlorides very rapidly and in good yields in the presence of titanium tetrachloride at low temperatures. These reactions proceed with exclusive retention of configuration.
authors.affiliation: Department of Chemistry, Florida Atlantic University, Boca Raton, Florida 33431-0991, USA. slepore@fau.edu
authors.forename: Salvatore D
authors.initials: SD
authors.lastname: Lepore
authors.forename: Anjan K
authors.initials: AK
authors.lastname: Bhunia
authors.forename: Deboprosad
authors.initials: D
authors.lastname: Mondal
authors.forename: Pamela C
authors.initials: PC
authors.lastname: Cohn
authors.forename: Craig
authors.initials: C
authors.lastname: Lefkowitz
mesh_terms: D000478:Alkylation; D001190:Arylsulfonates / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D015394:Molecular Structure; D013997:Time Factors; D014025:Titanium / Q000737:chemistry
chemical_list: D001190:Arylsulfonates; D002712:Chlorides; D004952:Esters; C025096:titanium tetrachloride; D014025:Titanium