title: [Three-dimensional vectorcardiography to predict CRT-responder].
abstract: Cardiac resynchronization therapy (CRT) is an accepted treatment for congestive heart failure (NYHA III-IV), but a substantial number of patients show no response to therapy. LBB, QRS width and echocardiographic measurements are parameters for indication, but they are not valid to predict hemodynamic response. A new method based on vector ECG analysis can deliver additional information, such as: parts or areas with late excitation, and with slow or fast depolarization speed. Electrical excitation is a prerequisite for contraction; this leads to the hypothesis that areas with late electrical activation will contract later. Algorithms for analysis of the vector ECG (determination of the vector -- time, area and speed) may help to identify responders and non-responders.
authors.affiliation: 2 Medizinische Abteilung, Landeskrankenhaus Klagenfurt, St.-Veiter-Strasse 47, 9020, Klagenfurt, Osterreich.
authors.forename: W
authors.initials: W
authors.lastname: Koglek
authors.forename: J
authors.initials: J
authors.lastname: Brandl
authors.forename: A
authors.initials: A
authors.lastname: Oberbichler
authors.forename: K
authors.initials: K
authors.lastname: Schmidt
authors.forename: G
authors.initials: G
authors.lastname: Grimm
authors.forename: C
authors.initials: C
authors.lastname: Butter
mesh_terms: D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000628:therapy*; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011379:Prognosis; D016896:Treatment Outcome; D014672:Vectorcardiography / Q000379:methods*