Effect of glycerol monocaprate (monocaprin) on broiler chickens: an attempt at reducing intestinal Campylobacter infection.
Attempts have been made by several workers to prevent or to reduce colonization of Campylobacter in the intestines of broiler chickens by adding antibacterial agents to their food, but the results have varied. Monocaprin, the 1-monoglyceride of capric acid, has been found to be very active in killing Campylobacter in vitro. It was therefore studied whether Campylobacter infection in chickens would be affected by adding emulsions of monocaprin to their drinking water and feed. It was found that treatment with monocaprin in water and feed did not prevent spread of Campylobacter from artificially infected to noninfected 24-d-old chickens, but Campylobacter counts in cloacal swabs were significantly reduced, particularly during the first 2 d of treatment. There was also a significant reduction in the Campylobacter counts in cloacal swabs of naturally infected 36-d-old broilers that were treated for 3 d prior to slaughter. Addition of monocaprin to drinking water and feed 2 to 3 d before slaughter might therefore be considered as a means of reducing Campylobacter infection in broilers, possibly in conjunction with other antibacterial agents such as short-chain organic acids. Further studies are needed to determine whether this would reduce carcass contamination.
Hilmarsson
H
H
Institute of Biology, Keldur, University of Iceland, 101 Reykjavik, Iceland.
Thormar
H
H
Thráinsson
J H
JH
Gunnarsson
E
E
Dadadóttir
S
S
D000818:Animals; D002169:Campylobacter Infections / Q000188:drug therapy / Q000662:veterinary*; D002353:Carrier State / Q000188:drug therapy / Q000382:microbiology; D002645:Chickens / Q000382:microbiology; D002988:Cloaca / Q000187:drug effects / Q000382:microbiology; D005260:Female; D005989:Glycerides / Q000494:pharmacology / Q000627:therapeutic use*; D007422:Intestines / Q000187:drug effects* / Q000382:microbiology*; D008297:Male; D011201:Poultry Diseases / Q000188:drug therapy* / Q000382:microbiology*; D014871:Water Microbiology
D005989:Glycerides; C004204:rac-glycerol 1-monodecanoate