[Gender influence on the immediate and medium-term progression after primary percutaneous coronary intervention and analysis of independent risk factors for death or events].
OBJECTIVE
Determine gender-related differences and risk factors for death and events, both in-hospital and at six-month evolution, of patients admitted within the first twelve hours of ST-segment elevation acute myocardial infarction and who underwent primary percutaneous coronary intervention.


METHODS
Between July 1998 and December 2000, 199 consecutive patients were enrolled in the study, with elevation myocardial infarction and without cardiogenic shock, outcome, in-hospital and six-month progression were studied.


RESULTS
Clinical characteristics were similar in both groups, except that women were older than men (67.04 +/- 11.53 x 59.70 +/- 10.88, p < 0.0001). In-hospital mortality was higher among women (9.1% x 1.5%, p = 0.0171), as was the incidence of major events (12.1% x 3.0%, p = 0.0026). The difference in mortality rates remained the same at six months (12.1% x 1.5%, p = 0.0026). The multivariate analysis predicted death: female gender and an age over eighty years, and major events and/or stable angina multivessel: disease and severe ventricular dysfunction.


CONCLUSIONS
Female gender and an age over eighty years were independent predictors of mortality, six months of patients who had undergone primary percutaneous intervention.
Peixoto
Rodrigo Trajano Sandoval
RT
Hospital Procordis, Universidade Federal Fluminense, Niterói, RJ.
Peixoto
Edison Carvalho Sandoval
EC
Sena
Marcello Augustus
MA
Tedeschi
Angelo Leone
AL
Borges
Ivana Picone
IP
Rachid
Maurício Bastos Freitas
MB
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000401:mortality / Q000473:pathology; D015906:Angioplasty, Balloon, Coronary; D018450:Disease Progression; D004812:Epidemiologic Methods; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D017678:Sex Distribution; D012737:Sex Factors; D016896:Treatment Outcome