title: Assessment of epoxidized soy bean oil (ESBO) migrating into foods: comparison with ESBO-like epoxy fatty acids in our normal diet.
abstract: Epoxidized soy bean oil (ESBO) was found to be toxic for rats, but the toxic constituent is unknown. It became an issue as the migration from the gaskets in the lids for jars into oily foods regularly far exceeds the European legal limit (overall migration limit and specific migration limit derived from the tolerable daily intake (TDI)). In the context of risk management it was of interest to determine the epoxidized fatty acids of ESBO in those foods of our normal diet which are expected to contain the highest concentrations, i.e., oxidized edible oils (including degraded frying oils), fried foods, bakery ware and roasted meat. The contribution of epoxy oleic acid from ESBO to our diet turned out to be negligible. If this acid were the toxic component in ESBO, the toxicological assessment would primarily be a warning regarding oxidized fats and oils. The contribution of diepoxy linoleic acid from ESBO might be similar to the exposure from oxidized fats and oils of our diet, whereas the intake of triepoxy linolenic acid from ESBO exceeds that from normal food by around two orders of magnitude. Hence use of an epoxidized edible oil virtually free of linolenic acid would be inconspicuous in our diet.
authors.affiliation: Official Food Control Authority of the Canton of Zürich, GC, Fehrenstrasse 15, P.O. Box, CH-8032 Zürich, Switzerland.
authors.forename: Anja
authors.initials: A
authors.lastname: Fankhauser-Noti
authors.forename: Katell
authors.initials: K
authors.lastname: Fiselier
authors.forename: Sandra
authors.initials: S
authors.lastname: Biedermann-Brem
authors.forename: Koni
authors.initials: K
authors.lastname: Grob
mesh_terms: D004852:Epoxy Compounds / Q000032:analysis / Q000737:chemistry*; D005231:Fatty Acids, Unsaturated / Q000032:analysis / Q000737:chemistry*; D005506:Food Contamination; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D010968:Plasticizers; D013024:Soybean Oil / Q000032:analysis / Q000737:chemistry*
chemical_list: D004852:Epoxy Compounds; D005231:Fatty Acids, Unsaturated; D010968:Plasticizers; D013024:Soybean Oil