[Neurotrophin and erectile dysfunction in diabetes].
Neurotrophins play significant roles in the development, differentiation and regeneration of many neurons. The abnormal changes of neurotrophins are one of the nosogenesis of diabetic peripheral neuropathy. Erectile dysfunction (ED) in diabetes is multifactorial and one of the most important causes is the injury of pelvic splanchnic nerves. Neurotrophins therapy shows exact effects on ED with pelvic splanchnic nerves injured. Recent researches indicates that the same treatment has the similar therapeutic effects on the ED animals with diabetes. Neurotrophins therapy develops a new way for us to cure the ED with diabetes.
Chen
Yun
Y
Department of Urology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu, China.
Dai
Yu-tian
YT
Sun
Ze-yu
ZY
D000818:Animals; D048909:Diabetes Complications / Q000150:complications*; D007172:Erectile Dysfunction / Q000209:etiology*; D008297:Male; D009414:Nerve Growth Factors / Q000502:physiology*; D051381:Rats
D009414:Nerve Growth Factors