title: Ectopic pregnancy in animals and humans.
abstract: Ectopic pregnancy denotes a pregnancy occurring elsewhere than in the cavity of the uterus. This pathology has been recognised for years and it causes numerous maternal deaths during the first trimester of pregnancy. While this condition is well-known in humans, it is rarely diagnosed in animals. However, the causes and mechanisms leading to an ectopic implantation of the ovum are not always clearly defined in humans or animals. Two types of ectopic pregnancy are mainly recognized: (1) tubal pregnancy occurs when an oocyte is fertilized and then remains in the oviduct and (2) abdominal pregnancy occurs when the gestation develops in the peritoneal cavity. The latter may be subdivided into two subtypes: the primary form, when a fertilized oocyte enters the peritoneal cavity and becomes attached to the mesentery or abdominal viscera, and the secondary form, which follows the rupture of an oviduct or the uterus after the fetus has been implanted, and the fetus is expelled into the peritoneal cavity. Cornual, ovarian and cervical ectopic locations are less frequent. Several differences exist in ectopic pregnancies between human beings and animal species. While abdominal pregnancy has been described in both human and animal species, tubal ectopic pregnancies would appear to be restricted to primates. Other than anecdotal cases, this pathological condition does not occur in laboratory, domestic or farm animals. Several factors are described as being the cause of these differences.
authors.affiliation: Departamento Atención Sanitaria, Salud Pública y Sanidad Animal (Histología y Anatomía Patológica), Facultad de Ciencias Experimentales y de la Salud, Universidad Cardenal Herrera-CEU, Edificio Seminario, Moncada (Valencia), Spain. jmcorpa@uch.ceu.es
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Corpa
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D000830:Animals, Laboratory; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011269:Pregnancy, Abdominal / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary; D011271:Pregnancy, Ectopic / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary; D011274:Pregnancy, Tubal / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary