Why RNA and DNA have different structures.
In the early years of molecular biology--over 50 years ago--we were faced with many unknowns. A significant one at the time was the relationship between DNA and RNA, both in terms of structure and function. Function is often a reflection of structure. Here I outline some of the early research in this area, especially for RNA structure, which was completely unknown when we started.
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Department of Biology, Massachusetts Institute of Technology, Cambridge MA, 02139, USA. cbeckman@mit.edu
D000818:Animals; D005075:Biological Evolution; D004247:DNA / Q000737:chemistry*; D006801:Humans; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D012330:RNA, Double-Stranded / Q000737:chemistry
D012330:RNA, Double-Stranded; D012313:RNA; D004247:DNA