title: Synthesis and herbicidal activity of novel alpha,alpha,alpha-trifluoro-m-tolyl pyridazinone derivatives.
abstract: A series of novel alpha,alpha,alpha-trifluoro-m-tolyl pyridazinone derivatives was synthesised. Herbicidal activities of the two intermediate compounds and 15 pyridazinone derivatives were evaluated through barnyardgrass and rape cup tests and Spirodela polyrrhiza (L.) Schleiden tests. Selected compounds were also evaluated under greenhouse conditions. Bleaching activities were observed at 10 microg ml(-1) and some compounds exhibited herbicidal activities at a rate of 300 g ha(-1). The relationship between crystal structures and herbicidal activities is discussed through a comparison of two compounds (5a and 5f).
authors.affiliation: State Key Laboratory of Elemento-Organic Chemistry, Elemento-Organic Chemistry Institute, Nankai University, Tianjin 300071, China.
authors.forename: Han
authors.initials: H
authors.lastname: Xu
authors.forename: Xiao-Mao
authors.initials: XM
authors.lastname: Zou
authors.forename: You-Quan
authors.initials: YQ
authors.lastname: Zhu
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Han-Lin
authors.initials: HL
authors.lastname: Tao
authors.forename: Xu-Hong
authors.initials: XH
authors.lastname: Hu
authors.forename: Hai-Bin
authors.initials: HB
authors.lastname: Song
authors.forename: Fang-Zhong
authors.initials: FZ
authors.lastname: Hu
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Hua-Zheng
authors.initials: HZ
authors.lastname: Yang
mesh_terms: D001937:Brassica / Q000187:drug effects / Q000254:growth & development; D031747:Echinochloa / Q000187:drug effects / Q000254:growth & development; D006540:Herbicides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000187:drug effects; D011724:Pyridazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D006540:Herbicides; D011724:Pyridazines