title: McKittrick-Wheelock syndrome: a rare cause of diarrhoea.
abstract: McKittrick-Wheelock syndrome is a rare disorder caused by fluid and electrolyte hypersecretion from a rectal tumour. The most frequently reported tumours are villous adenomas. Dehydration with severe hyponatremia, hypokalemia, metabolic acidosis, acute renal failure and watery diarrhoea is typical. The authors present a case of McKittrick-Wheelock syndrome caused by rectal adenocarcinoma.
authors.affiliation: Department of Neuroinfections and Intensive Care Medicine, University Hospital for Infectious Diseases "Dr Fran Mihaljević", Mirogojska 8, 10000 Zagreb, Croatia. lepurix@inet.hr
authors.forename: Dragan
authors.initials: D
authors.lastname: Lepur
authors.forename: Igor
authors.initials: I
authors.lastname: Klinar
authors.forename: Branko
authors.initials: B
authors.lastname: Mise
authors.forename: Josip
authors.initials: J
authors.lastname: Himbele
authors.forename: Zoran
authors.initials: Z
authors.lastname: Vranjican
authors.forename: Bruno
authors.initials: B
authors.lastname: Barsić
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000601:surgery; D003967:Diarrhea / Q000209:etiology* / Q000628:therapy; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D007552:Isotonic Solutions / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000150:complications* / Q000601:surgery; D013577:Syndrome; D016896:Treatment Outcome; D014883:Water-Electrolyte Imbalance / Q000150:complications / Q000628:therapy
chemical_list: D007552:Isotonic Solutions