title: Most patients with multiple sclerosis or a clinically isolated demyelinating syndrome should be treated at the time of diagnosis.
authors.affiliation: Departments of Neurology and Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA. elliot.frohman@utsouthwestern.edu
authors.forename: E M
authors.initials: EM
authors.lastname: Frohman
authors.forename: E
authors.initials: E
authors.lastname: Havrdova
authors.forename: F
authors.initials: F
authors.lastname: Lublin
authors.forename: F
authors.initials: F
authors.lastname: Barkhof
authors.forename: A
authors.initials: A
authors.lastname: Achiron
authors.forename: M K
authors.initials: MK
authors.lastname: Sharief
authors.forename: O
authors.initials: O
authors.lastname: Stuve
authors.forename: M K
authors.initials: MK
authors.lastname: Racke
authors.forename: L
authors.initials: L
authors.lastname: Steinman
authors.forename: H
authors.initials: H
authors.lastname: Weiner
authors.forename: M
authors.initials: M
authors.lastname: Olek
authors.forename: R
authors.initials: R
authors.lastname: Zivadinov
authors.forename: J
authors.initials: J
authors.lastname: Corboy
authors.forename: C
authors.initials: C
authors.lastname: Raine
authors.forename: G
authors.initials: G
authors.lastname: Cutter
authors.forename: J
authors.initials: J
authors.lastname: Richert
authors.forename: M
authors.initials: M
authors.lastname: Filippi
mesh_terms: D002985:Clinical Protocols; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D042241:Early Diagnosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging / Q000592:standards; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy*; D018579:Patient Selection; D011237:Predictive Value of Tests; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic / Q000592:standards; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents