title: [LMP-420, a new therapeutic approach for cerebral malaria?].
authors.forename: Samuel C
authors.initials: SC
authors.lastname: Wassmer
authors.forename: George J
authors.initials: GJ
authors.lastname: Cianciolo
authors.forename: Valéry
authors.initials: V
authors.lastname: Combes
authors.forename: Georges E
authors.initials: GE
authors.lastname: Grau
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use*; D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D001896:Boron Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D002448:Cell Adhesion / Q000187:drug effects; D002478:Cells, Cultured / Q000187:drug effects / Q000378:metabolism; D018932:Chemokine CCL2 / Q000037:antagonists & inhibitors / Q000378:metabolism; D002675:Child, Preschool; D003864:Depression, Chemical; D004353:Drug Evaluation, Preclinical; D042783:Endothelial Cells / Q000187:drug effects / Q000378:metabolism; D005260:Female; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D020672:I-kappa B Proteins / Q000378:metabolism; D007223:Infant; D007231:Infant, Newborn; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis / Q000235:genetics; D016779:Malaria, Cerebral / Q000188:drug therapy*; D016778:Malaria, Falciparum / Q000188:drug therapy; D008297:Male; D016328:NF-kappa B / Q000378:metabolism; D010766:Phosphorylation / Q000187:drug effects; D010963:Plasmodium falciparum / Q000502:physiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D011687:Purines / Q000494:pharmacology / Q000627:therapeutic use*; D011956:Receptors, Cell Surface / Q000187:drug effects; D018417:Th1 Cells / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*; D019010:Vascular Cell Adhesion Molecule-1 / Q000096:biosynthesis / Q000235:genetics
chemical_list: C511928:2-amino-6-chloro-9-((5-dihydroxyboryl)pentyl)purine; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000962:Antimalarials; D001896:Boron Compounds; C111835:CCL2 protein, human; D018932:Chemokine CCL2; D020672:I-kappa B Proteins; D016328:NF-kappa B; D011687:Purines; D011956:Receptors, Cell Surface; D014409:Tumor Necrosis Factor-alpha; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1