Asymmetric transfer hydrogenation of imines and iminiums catalyzed by a water-soluble catalyst in water.
The first asymmetric transfer hydrogenation of cyclic imines and iminiums in water was successfully performed in high yields and enantioselectivities with sodium formate as the hydrogen source and CTAB as an additive catalyzed by a water-soluble and recyclable ruthenium(II) complex of the ligand (R,R)-2.
Wu
Jiashou
J
Key Laboratory of Asymmetric & Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China. jgdeng@cioc.ac.cn
Wang
Fei
F
Ma
Yaping
Y
Cui
Xin
X
Cun
Linfeng
L
Zhu
Jin
J
Deng
Jingen
J
Yu
Bangliang
B