Rhodium-catalyzed tandem vinylcyclopropanation of strained alkenes.
This communication reports an unusual rhodium-catalyzed 1,6-addition of a dienylboronate ester to highly strained alkenes. The resulting vinylcyclopropane-fused tricyclic products were produced in moderate to good yields. Preliminary mechanistic studies are also presented.
Tseng
Nai-Wen
NW
Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada M5S 3H6.
Mancuso
John
J
Lautens
Mark
M