title: A new drug-release method using the Staudinger ligation.
abstract: Many drugs induce severe side-effects caused by their lack of selectivity. One way to overcome this problem is to design a specific system which releases a free drug in a controlled manner. Herein we describe a new way to liberate a drug from a prodrug using the Staudinger ligation as the trigger.
authors.affiliation: UMR 176 CNRS/Institut Curie, Centre de Recherche, 26 rue d'Ulm, F-75248 Paris Cedex 05, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Azoulay
authors.forename: Gérald
authors.initials: G
authors.lastname: Tuffin
authors.forename: Wafa
authors.initials: W
authors.lastname: Sallem
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Florent
mesh_terms: D000588:Amines / Q000737:chemistry; D004317:Doxorubicin / Q000737:chemistry; D015394:Molecular Structure; D011355:Prodrugs / Q000737:chemistry*
chemical_list: D000588:Amines; D011355:Prodrugs; D004317:Doxorubicin