title: [The role of tumor necrosis factor (TNF-alpha) in control of metabolism].
abstract: Tumor necrosis factor is multifunctional cytokine involved in various cell functions, such as differentiation, mitosis, angiogenesis, inflammation and immune controls. TNF-alpha plays also an important role in the control of metabolism. Its action on adipocytes includes increasing secretion of triglicerydes and inhibiting insulin action, controlling expression of some genes and modulating free fatty acid and leptin secretion. The review of the current literature on the TNF-alpha role in metabolism is presented in this paper.
authors.affiliation: Katedry Patofizjologii Sla,skiej Akademii Medycznej, Katowicach. magols@esculap.pl
authors.forename: Magdalena
authors.initials: M
authors.lastname: Olszanecka-Glinianowicz
authors.forename: Barbara
authors.initials: B
authors.lastname: Zahorska-Markiewicz
authors.forename: Aleksander
authors.initials: A
authors.lastname: Zurakowski
authors.forename: Mariusz
authors.initials: M
authors.lastname: Glinianowicz
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000502:physiology; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D008066:Lipolysis / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism / Q000502:physiology*
chemical_list: D005230:Fatty Acids, Nonesterified; D014409:Tumor Necrosis Factor-alpha