title: [Effect of alveolar surgery-aided rapid orthodontic tooth movement on bone formation].
abstract: OBJECTIVE
  To test the effect of alveolar surgery on orthodontic tooth movement and born remodeling.
  
  
  METHODS
  Alveolar surgery was performed on one side (experimental side) whereas the traditional tooth movement was performed on the other side (control side) of the teeth in ten dogs. The treatments lasted for four weeks. The bone formation was evaluated using the vital bone marker tetracycline and immunohistochemistry 1, 2, 3, 4 and 8 weeks after the treatments respectively.
  
  
  RESULTS
  In the total of the four weeks, the distal movement of experimental tooth was much faster (4.31 +/- 0.46 mm) than control tooth (2.16 +/- 0.42 mm), whereas the anchorage lost (0.44 +/- 0.07 mm) was the same with the control (0.46 +/- 0.09 mm). Compared to the control side, the tetracycline labeling lines were wider; the increase of the expression level of BMP-2 appeared earlier, greater and lasted longer in the tension area of the experimental side.
  
  
  CONCLUSIONS
  Alveolar surgery could promote bone remodeling and accelerate the movement of orthodontic teeth.
authors.affiliation: Department of Orthodontic, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Na
authors.initials: N
authors.lastname: Kang
authors.forename: Tao
authors.initials: T
authors.lastname: Lü
authors.forename: Ai-Shu
authors.initials: AS
authors.lastname: Ren
authors.forename: Lan
authors.initials: L
authors.lastname: Huang
authors.forename: Ding
authors.initials: D
authors.lastname: Bai
mesh_terms: D000539:Alveolar Process / Q000601:surgery*; D000818:Animals; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000096:biosynthesis / Q000235:genetics; D016723:Bone Remodeling; D004285:Dogs; D008297:Male; D009967:Orthodontic Appliances; D014087:Tooth Movement Techniques; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics
chemical_list: D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta