title: [Susceptibility to norfloxacin of some bacterial strains causing urinary infections].
abstract: The purpose of this study was to evaluate the in vitro activity of norfloxacin in comparison with ofloxacin, pefloxacin and ciprofloxacin against 662 strains. The studied strains were obtained from urine, during 2003 period, in Eastern region of Romania. The minimum inhibitory concentrations (MICs) were determined on Mueller-Hinton agar by the dilution technique, with an inoculum of 10(5) CFU/spot. Among tested quinolones, norfloxacin has the better activity against tested strains. The fluoroquinolone compounds were very potent against Escherichia coil strains. Our data shown the spread of quinolone resistance in our area and demonstrated the necessity of adequate antibiotic use in the hospital and community.
authors.affiliation: Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi, Facultatea de Farmacie, Disciplina Microbiologie.
authors.forename: Cristina
authors.initials: C
authors.lastname: Tuchiluş
authors.forename: Antonia
authors.initials: A
authors.lastname: Poiată
authors.forename: Ioana
authors.initials: I
authors.lastname: Bădicuţ
authors.forename: D
authors.initials: D
authors.lastname: Buiuc
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000494:pharmacology*; D015242:Ofloxacin / Q000494:pharmacology; D015366:Pefloxacin / Q000494:pharmacology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D015366:Pefloxacin; D002939:Ciprofloxacin; D015242:Ofloxacin; D009643:Norfloxacin