[Intratumor bleomycin-A5 injection under electrolaryngoscope for treatment of large laryngopharyngeal and laryngeal hemangioma].
OBJECTIVE
To study the therapeutic effect of bleomycin-A5 injection under eletrolaryngoscope for treatment of large laryngopharyngeal and laryngeal hemangioma.


METHODS
Intratumor bleomycin-A5 injection under eletrolaryngoscope was performed in 18 cases of large laryngopharyngeal and laryngeal hemangioma with surface anaesthesia, for totally 7 to 14 (mean 10.2) injections in each case.


RESULTS
Twelve patients were cured and 6 showed obvious improvement. Follow-up of the patients for over one year found no recurrence of the hemangioma.


CONCLUSIONS
Bleomycin-A5 injection is a minimal invasive procedure for treatment of large laryngopharyngeal and laryngeal hemangioma, causing less pain and better preserving the laryngeal function without the necessity of tracheotomy.
Huang
Yi-deng
YD
Department of Otolaryngology, 118 Hospital of PLA, Wenzhou 325000, China. huangyideng@sohu.com
Chen
Jian-fu
JF
Xia
Si-wen
SW
Huang
Zi-xi
ZX
Wang
Guang-yao
GY
Luo
Xing-hua
XH
Luo
Chun-juan
CJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D001761:Bleomycin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D020704:Laryngoscopes; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000188:drug therapy*
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin; C025703:bleomycetin