Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives.
Diastereoselective aldol coupling reactions with butane-2,3-diacetal (BDA) protected glyceraldehyde derivatives are reported. Good selectivities of up to 20:1 for the homologated aldol products have been achieved in preparatively useful yields.
Knudsen
Kristian Rahbek
KR
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW.
Stepan
Antonia F
AF
Michel
Patrick
P
Ley
Steven V
SV
D000080:Acetals / Q000737:chemistry*; D002384:Catalysis; D005985:Glyceraldehyde / Q000031:analogs & derivatives* / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D000080:Acetals; C521723:glyceraldehyde butane-2,3-diacetal; D005985:Glyceraldehyde