title: [The practice guideline 'Urinary-tract infections' (second revision) from the Dutch College of General Practitioners; a response from the perspective of general practice].
abstract: The Dutch College of General Practitioners recently published an update of the practice guideline on urinary-tract infections. This guideline provides a clear overview of the medical history, the diagnostic methods and the treatment options. Sixteen management modalities are presented in relation to specific patient characteristics. However, this revised guideline warrants some minor comments. According to the guideline, the dipstick (nitrite) test and dipslide form the two cornerstones of the diagnosis of urinary-tract infections. The value of the dipslide, however, seems to have been overestimated and that of microscopic examination of the urine by skilled physicians to have been underestimated. New in this guideline compared to that of 1999 is that nitrofurantoin (the treatment of first choice in uncomplicated infections) should be given for five instead of three days. The guideline motivates this change in policy on the basis of the numerous treatment failures seen in practice. The most convincing type of evidence, however, is not available due to the lack of relevant randomised clinical trials. The introduction of the prescription of phosphomycin, which is unusual in the Netherlands, as an alternative treatment for uncomplicated infections requires supportive evidence before it will be accepted by general practitioners. This well-documented guideline provides clear guidance for the general practitioner faced with patients with urinary-tract symptoms that could be caused by infection.
authors.affiliation: VU Medisch Centrum, Instituut voor Extramuraal Geneeskundig Onderzoek (EMGO Instituut), onderzoeksgroep Huisartsgeneeskunde, Van der Boechorststraat 7, 1081 BT Amsterdam.
authors.forename: A J P
authors.initials: AJ
authors.lastname: Boeke
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005194:Family Practice / Q000592:standards*; D006801:Humans; D009426:Netherlands; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D017211:Treatment Failure; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000188:drug therapy*; D014572:Urology / Q000592:standards*
chemical_list: D000900:Anti-Bacterial Agents