Incidence of haemoglobinopathies detected through neonatal screening in the United Arab Emirates.
In January 2002, a pilot programme of neonatal screening for sickle cell disease was launched in the United Arab Emirates (UAE) in 3 districts of Abu Dhabi emirate. This paper reports the incidence of sickle cell diseases, other haemoglobinopathies and haemoglobinopathy carriers over a 12-month period using high performance liquid chromatography as a primary screening method. The overall incidence of sickle cell disease among 22 200 screened neonates was 0.04% (0.07% for UAE citizens and 0.02% for non-UAE citizens). The incidence of sickle cell trait was 1.1% overall (1.5% for UAE citizens and 0.8% for non-UAE citizens). Universal neonatal screening for sickle cell haemoglobin at the national level should be considered.
Al Hosani
H
H
Central Department of Maternal and Child Health, Ministry of Health, Abu-Dhabi, United Arab Emirates.
Salah
M
M
Osman
H M
HM
Farag
H M
HM
Anvery
S M
SM
D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D001723:Birth Rate; D002851:Chromatography, High Pressure Liquid; D005500:Follow-Up Studies; D005817:Genetic Counseling; D005820:Genetic Testing / Q000379:methods / Q000706:statistics & numerical data; D006301:Health Services Needs and Demand; D006445:Hemoglobin C Disease / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D006446:Hemoglobin E; D006453:Hemoglobinopathies / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D006455:Hemoglobins, Abnormal; D006579:Heterozygote; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods / Q000706:statistics & numerical data; D010865:Pilot Projects; D011159:Population Surveillance; D011296:Prenatal Diagnosis; D012111:Residence Characteristics / Q000706:statistics & numerical data; D012307:Risk Factors; D012805:Sickle Cell Trait / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D013789:Thalassemia / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D014479:United Arab Emirates / Q000453:epidemiology
D006455:Hemoglobins, Abnormal; C032001:hemoglobin D; D006446:Hemoglobin E