title: Relationships between the abnormalities of the male reproductive organs and the accumulation of phenol compounds in the striped field mouse, Apodemus agrarius, inhabiting Korea.
abstract: The relationships between the abnormalities of the male reproductive organs in striped field mice and the accumulation of endocrine-disrupting chemicals were assessed. Most mice collected at three areas were contaminated with phenol or organotin compounds. Fourteen to 42% of the mice at each area had abnormally shrunken reproductive organs, and some of them were contaminated with high levels of phenol compounds. Moreover, all the shrunken reproductive organs were damaged in the histological structure. The damage was observed also from several mice accumulating a high level of phenol compounds even though they had normally developed reproductive organs, although no damage was found in the mice accumulating a high level of organotin compounds. Collectively, the abnormalities of the reproductive organs in the mice seemed to be related to the accumulation of phenol compounds rather than of organotin compounds.
authors.affiliation: Department of Biology, Kyungsung University, 341-79 Daeyeon-dong, Nam-gu, Busan 608-736, South Korea.
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Kim
authors.forename: Myung-Hee
authors.initials: MH
authors.lastname: Yoon
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ueda
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Honda
authors.forename: Byung-Yoon
authors.initials: BY
authors.lastname: Min
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds; D001835:Body Weight; D004051:Diethylhexyl Phthalate / Q000032:analysis; D052244:Endocrine Disruptors / Q000032:analysis*; D004787:Environmental Pollution / Q000032:analysis*; D004822:Epididymis / Q000002:abnormalities; D005837:Genitalia, Male / Q000002:abnormalities* / Q000187:drug effects; D007723:Korea; D008297:Male; D051189:Murinae; D009929:Organ Size; D009947:Organotin Compounds / Q000032:analysis; D010636:Phenols / Q000032:analysis*; D013737:Testis / Q000002:abnormalities; D014220:Trialkyltin Compounds / Q000032:analysis; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004051:Diethylhexyl Phthalate; D052244:Endocrine Disruptors; D009947:Organotin Compounds; D010636:Phenols; D014220:Trialkyltin Compounds; C056189:di-n-butyltin; C011559:tributyltin; C025256:nonylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds