title: [Cutaneous side effects of a long-term treatment by hydroxyurea].
abstract: Hydroxyurea is an antitumour agent used most commonly to treat myeloproliferative disorders. We present a clinical observation illustrating different cutaneous side effects susceptible to occur during a long-term treatment by hydroxyurea : leg ulceration, oral ulcer and spinocellular carcinoma. This clinical observation is completed by a review of the literature published on the cutaneous side effects of hydroxyurea treatment.
authors.affiliation: Service de Dermatologie, Hôpital Erasme, CHIREC, Site Edith Cavell.
authors.forename: E
authors.initials: E
authors.lastname: Steels
authors.forename: M
authors.initials: M
authors.lastname: Heenen
authors.forename: M A
authors.initials: MA
authors.lastname: Germaux
authors.forename: J P
authors.initials: JP
authors.lastname: Moens
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002277:Carcinoma / Q000139:chemically induced; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects* / Q000627:therapeutic use; D007871:Leg Ulcer / Q000139:chemically induced*; D008297:Male; D009196:Myeloproliferative Disorders / Q000188:drug therapy; D019226:Oral Ulcer / Q000139:chemically induced*; D012878:Skin Neoplasms / Q000139:chemically induced
chemical_list: D000970:Antineoplastic Agents; D006918:Hydroxyurea