title: A sensor to detect the early stages in the development of crystalline Proteus mirabilis biofilm on indwelling bladder catheters.
abstract: A simple sensor has been developed to detect the early stages of urinary catheter encrustation and avoid the clinical crises induced by catheter blockage. In laboratory models of colonization by Proteus mirabilis, the sensor signaled encrustation at an average time of 43 h before catheters were blocked with crystalline biofilm.
authors.affiliation: Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom. stickler@cardiff.ac.uk
authors.forename: D J
authors.initials: DJ
authors.lastname: Stickler
authors.forename: S M
authors.initials: SM
authors.lastname: Jones
authors.forename: G O
authors.initials: GO
authors.lastname: Adusei
authors.forename: M G
authors.initials: MG
authors.lastname: Waters
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D001979:Bromthymol Blue / Q000378:metabolism; D002408:Catheters, Indwelling / Q000382:microbiology*; D003460:Crystallization; D004866:Equipment Contamination / Q000517:prevention & control*; D011513:Proteus mirabilis / Q000378:metabolism* / Q000502:physiology; D014546:Urinary Catheterization; D014552:Urinary Tract Infections / Q000382:microbiology
chemical_list: D001979:Bromthymol Blue