title: The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome.
abstract: We assessed the effect of the Duarte (N314D) variant in the GALT gene on in vitro fertilization outcome measures. Our data do not definitely exclude variants in the GALT gene as factors influencing outcome, but the lack of suggestive evidence makes it difficult to justify a larger, more definitive study.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom. stephen.kennedy@obs-gyn.ox.ac.uk
authors.forename: Shigeki
authors.initials: S
authors.lastname: Yoshida
authors.forename: Jo
authors.initials: J
authors.lastname: Steele
authors.forename: John
authors.initials: J
authors.lastname: Koninckx
authors.forename: Enda
authors.initials: E
authors.lastname: McVeigh
authors.forename: Stephen
authors.initials: S
authors.lastname: Kennedy
mesh_terms: D000328:Adult; D001120:Arginine; D001216:Asparagine; D001224:Aspartic Acid; D016022:Case-Control Studies; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D005787:Gene Frequency; D014644:Genetic Variation; D005838:Genotype; D005973:Glutamine; D006801:Humans; D007246:Infertility / Q000235:genetics* / Q000628:therapy*; D009154:Mutation; D011247:Pregnancy; D018873:Pregnancy Rate; D016896:Treatment Outcome; D006599:UDPglucose-Hexose-1-Phosphate Uridylyltransferase / Q000235:genetics*
chemical_list: D005973:Glutamine; D001224:Aspartic Acid; D001216:Asparagine; D001120:Arginine; D006599:UDPglucose-Hexose-1-Phosphate Uridylyltransferase