title: Evaluation of diagnostic assays for hepatitis E virus in outbreak settings.
abstract: Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific.
authors.affiliation: Department of Virology, USAMC-AFRIMS, 315/6 Rajvithi Road, Bangkok 1040, Thailand. myintk@afrims.org
authors.forename: Khin Saw Aye
authors.initials: KS
authors.lastname: Myint
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Endy
authors.forename: Robert V
authors.initials: RV
authors.lastname: Gibbons
authors.forename: Kanti
authors.initials: K
authors.lastname: Laras
authors.forename: Mammen P
authors.initials: MP
authors.lastname: Mammen
authors.forename: Endang R
authors.initials: ER
authors.lastname: Sedyaningsih
authors.forename: Jitvimol
authors.initials: J
authors.lastname: Seriwatana
authors.forename: Jonathan S
authors.initials: JS
authors.lastname: Glass
authors.forename: Sumitda
authors.initials: S
authors.lastname: Narupiti
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Corwin
mesh_terms: D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000032:analysis; D004196:Disease Outbreaks; D006508:Hepatitis Antibodies / Q000097:blood; D016751:Hepatitis E / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology; D016752:Hepatitis E virus / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods / Q000592:standards; D012189:Retrospective Studies
chemical_list: D004279:DNA, Viral; D006508:Hepatitis Antibodies