[Effect of alveolar surgery-aided rapid orthodontic tooth movement on bone formation].
OBJECTIVE
To test the effect of alveolar surgery on orthodontic tooth movement and born remodeling.


METHODS
Alveolar surgery was performed on one side (experimental side) whereas the traditional tooth movement was performed on the other side (control side) of the teeth in ten dogs. The treatments lasted for four weeks. The bone formation was evaluated using the vital bone marker tetracycline and immunohistochemistry 1, 2, 3, 4 and 8 weeks after the treatments respectively.


RESULTS
In the total of the four weeks, the distal movement of experimental tooth was much faster (4.31 +/- 0.46 mm) than control tooth (2.16 +/- 0.42 mm), whereas the anchorage lost (0.44 +/- 0.07 mm) was the same with the control (0.46 +/- 0.09 mm). Compared to the control side, the tetracycline labeling lines were wider; the increase of the expression level of BMP-2 appeared earlier, greater and lasted longer in the tension area of the experimental side.


CONCLUSIONS
Alveolar surgery could promote bone remodeling and accelerate the movement of orthodontic teeth.
Kang
Na
N
Department of Orthodontic, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Lü
Tao
T
Ren
Ai-Shu
AS
Huang
Lan
L
Bai
Ding
D
D000539:Alveolar Process / Q000601:surgery*; D000818:Animals; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000096:biosynthesis / Q000235:genetics; D016723:Bone Remodeling; D004285:Dogs; D008297:Male; D009967:Orthodontic Appliances; D014087:Tooth Movement Techniques; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics
D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta