[Study on the process of inclusion volatile oil of Herba Schizonepetae with beta-cyclodextrin from xiao'er ganmaoshu granule].
OBJECTIVE
To study optimum inclusion process condition for volatile oil with beta-cyclodextrin (beta-CD).


METHODS
The optimum preparation condition were investigated by orthogonal design. The influence of utilization beta-CD and oil, inclusion temperature and time were studied to determin the utilization ratio of volatile oil and oil-bearing rate.


RESULTS
The optimum preparation conditions were established as: volatile oil: beta-CD was 1:10, the inclusion temperature was 60 degrees C and inclusion time was 3h.


CONCLUSIONS
The method is convenient and can he used for mass production.
Zhao
Kai-jun
KJ
Najing Zhongshan Pharmaceutical Factory, Najing 210012, China.
Pu
Cun-hai
CH
Guan
Zhi-yu
ZY
D000704:Analysis of Variance; D004337:Drug Carriers; D004338:Drug Combinations; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000737:chemistry*; D019686:Lamiaceae / Q000737:chemistry*; D009822:Oils, Volatile / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D047392:beta-Cyclodextrins / Q000737:chemistry
D004337:Drug Carriers; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D047392:beta-Cyclodextrins