Recurrent fetal hydrops due to mucopolysaccharidoses type VII.
Hydrops fetalis is associated with a wide range of abnormalities. In about 20% of cases of non-immune fetal hydrops, no cause is found despite investigations including routine post-mortem examination and enzyme studies may be indicated to detect an underlying metabolic storage disease. Fetal hydrops due to mucopolysaccharidosis type VII is very rare and a prenatal diagnosis is not usually made. We report a case of mucopolysaccharidosis type VII presenting as recurrent fetal hydrops and review the clinico-pathological features of this disorder.
Venkat-Raman
Narayanaswamy
N
Fetal Medicine Unit, St Mary's Hospital, London, UK. venkatraman@btinternet.com
Sebire
Neil J
NJ
Murphy
Karl W
KW
D000005:Abdomen / Q000000981:diagnostic imaging / Q000196:embryology; D000328:Adult; D001201:Ascites; D003241:Consanguinity; D005260:Female; D005865:Gestational Age; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000209:etiology*; D016538:Mucopolysaccharidosis VII / Q000150:complications* / Q000175:diagnosis*; D048208:Nuchal Translucency Measurement; D011247:Pregnancy; D012008:Recurrence; D016216:Ultrasonography, Prenatal