Giant paraovarian myxoma.
We present an extremely rare case of a successfully operated giant (6700 g) paraovarian myxoma and uterus myomatosus in a 49-year-old woman. Preoperative examination (biochemical investigations, ultrasound and computed tomography scan) and perioperative findings did not identify a malignant tumor so that total abdominal hysterectomy/bilateral salpingo-oophorectomy and tumorectomy was chosen to treat the patient. Histologically, the tumor was clearly differentiated from the surrounding tissue. In solid regions there were spindle-shaped cells arranged in sheaves and within the profuse, well-vascularized myxomatous stroma there were star-shaped cells. Immunohistochemical analysis showed that tumor cells were positive to vimentin and smooth muscle actin. Electron microscopic analysis showed that tumor cells had ultrastructural characteristics that corresponded to cells in fibroma and thecoma in a profuse intercellular matrix, which confirmed the result of light microscopy.
Habek
Dubravko
D
Department of Obstetrics and Gynecology, School of Medicine, Zagreb University, Sveti Duh Hospital Zagreb, Zagreb, Croatia. dubravko.habek@os.t-com.hr
Dmitrovic
Branko
B
Popovic
Zoran
Z
Karsa
Matija
M
Blazicvic
Valerija
V
Rupcic
Branko
B
Vlahovic
Mirna Erman
ME
Marjanovic
Ksenija
K
D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000150:complications / Q000473:pathology; D008875:Middle Aged; D009232:Myxoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology