The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome.
We assessed the effect of the Duarte (N314D) variant in the GALT gene on in vitro fertilization outcome measures. Our data do not definitely exclude variants in the GALT gene as factors influencing outcome, but the lack of suggestive evidence makes it difficult to justify a larger, more definitive study.
Yoshida
Shigeki
S
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom. stephen.kennedy@obs-gyn.ox.ac.uk
Steele
Jo
J
Koninckx
John
J
McVeigh
Enda
E
Kennedy
Stephen
S
D000328:Adult; D001120:Arginine; D001216:Asparagine; D001224:Aspartic Acid; D016022:Case-Control Studies; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D005787:Gene Frequency; D014644:Genetic Variation; D005838:Genotype; D005973:Glutamine; D006801:Humans; D007246:Infertility / Q000235:genetics* / Q000628:therapy*; D009154:Mutation; D011247:Pregnancy; D018873:Pregnancy Rate; D016896:Treatment Outcome; D006599:UDPglucose-Hexose-1-Phosphate Uridylyltransferase / Q000235:genetics*
D005973:Glutamine; D001224:Aspartic Acid; D001216:Asparagine; D001120:Arginine; D006599:UDPglucose-Hexose-1-Phosphate Uridylyltransferase