[Mandibular resorption, an underdiagnosed manifestation of systemic scleroderma].
BACKGROUND
Systemic sclerosis (SSc) is sometimes associated with bone resorption that can reach the mandible.


METHODS
We report here the cases of two women (aged 47 and 57 years) with SSc diagnosed 13 and 26 years earlier, respectively. Both presented marked mandibular bone resorption. The first had prominent interstitial lung disease, and the second, who died within a few months, had severe left ventricular dysfunction due to SSc.


CONCLUSIONS
Mandibular resorption is a rare but probably underdiagnosed manifestation of SSc. In addition to its esthetic effects, it can cause severe disability.
Charles
Pierre
P
Université Paris-Descartes, Faculté de Médecine, Service de Médecine Interne, Centre de Référence National pour la Sclérodermie et les Vascularites Systémiques, Hôpital Cochin, AP-HP, Paris.
Berezné
Alice
A
Guillevin
Loïc
L
Mouthon
Luc
L
D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed