PGRP-LB minds the fort.
Peptidoglycan recognition proteins (PGRPs) are a class of molecules that play a critical role in Drosophila immunity. In this issue of Immunity, Zaidman-Rémy et al. (2006) show that PGRP-LB controls systemic immune responses as well as homeostasis at the barrier surfaces.
Girardin
Stephen E
SE
Department of Laboratory Medicine and Pathobiology, Medical Sciences Building, University of Toronto, Toronto, M5S 1A8, Canada.
Philpott
Dana J
DJ
D000818:Animals; D002352:Carrier Proteins / Q000276:immunology*; D004330:Drosophila / Q000276:immunology*; D029721:Drosophila Proteins / Q000276:immunology*; D006801:Humans
D002352:Carrier Proteins; D029721:Drosophila Proteins; C118897:peptidoglycan recognition protein