title: Anion-templated assembly of [2]rotaxanes.
abstract: Anion templation is used to develop a general method for rotaxane synthesis. The anion-templated synthesis of three new [2]rotaxanes containing positively charged pyridinium axles and neutral isophthalamide macrocyclic components is described. The incorporation of electron withdrawing substituents, such as the nitro group, into the 5-position of an isophthalamide bis-vinyl acyclic precursor results in a significant improvement in [2]rotaxane assembly yields. Rotaxane anion binding strengths are also enhanced whilst the rotaxane's unique interlocked binding domain ensures selectivity for chloride--the templating anion--is maintained.
authors.affiliation: Department of Chemistry, Inorganic Chemistry Laboratory, University of Oxford, South Parks Road, Oxford, UK OX1 3QR.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Sambrook
authors.forename: Paul D
authors.initials: PD
authors.lastname: Beer
authors.forename: Michael D
authors.initials: MD
authors.lastname: Lankshear
authors.forename: R Frederick
authors.initials: RF
authors.lastname: Ludlow
authors.forename: James A
authors.initials: JA
authors.lastname: Wisner