[Influence of Diabetes Mellitus on immediate results of coronary stent: National Center for Cardiovascular Interventions (CENIC) data analysis].
OBJECTIVE
This study sought to investigate the influence of Diabetes Mellitus (DM) on immediate results after coronary stenting implantation (CSI) according to clinical presentation.


METHODS
Between January, 1997 and December, 2003, 11,874 diabetic patients underwent CSI, as recorded by CENIC database: 7,386 (62.3%) had chronic coronary disease (CCD); 3,142 (26.4%) acute coronary syndrome with non-ST segment elevation (ACSNST); and 1,346 (11.3%), reported acute myocardial infarction (AMI), with ST Segment elevation. Those groups were compared with 48,103 non-diabetics: 30,980 (64.5%) with CCD; 10,938 (22.7%), with non-elevated ST segments and unstable angina; and 6,185 (12.8%), with AMI.


RESULTS
Diabetic patients presented worse clinical and angiographic characteristics. Diabetics with CCD showed similar incidence of MACE as compared to non-diabetics (0.98% x 0.91%, p = 0.5971); however, diabetics with ACSNST and AMI reported higher incidence of events: 2.76% x 1.46% (p < 0.0001) and 7.87% x 4.1% (p < 0.0001), respectively. Multivariate analysis showed DM to act as independent risk predictor for larger adverse events under non-elevated ST segment and unstable angina (ACSNST) (OR: 1.92 CI: 1.46-2.52 p < 0.0001) and with AMI (OR: 2.0 CI: 1.57-2.54 p < or = 0.0001) and no influence for CCD (OR: 1.08 CI: 0.83-1.42 p = 0.5470.


CONCLUSIONS
Diabetic patients with CCD reported similar outcome as compared to the non-diabetics; however, those with ACSNST and AMI presented higher incidence of major adverse cardiac events during hospital stay.
Moscoso
Isaac
I
Central Nacional de Intervenções Cardiovasculares, Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista, São Paulo, SP.
Garcia
Lázaro Claudiovino
LC
Dourado
Gilvan Oliveira
GO
Mauro
Maria Fernanda Z
MF
Caramori
Paulo
P
Coelho
Wilson
W
Lima
Valter
V
Bueno
Ronaldo
R
Mangione
José A
JA
D000789:Angina, Unstable / Q000401:mortality / Q000601:surgery; D001938:Brazil / Q000453:epidemiology; D003327:Coronary Disease / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D016208:Databases, Factual; D003925:Diabetic Angiopathies / Q000401:mortality / Q000601:surgery*; D004812:Epidemiologic Methods; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000601:surgery; D015607:Stents / Q000009:adverse effects*; D013577:Syndrome; D016896:Treatment Outcome