title: Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development.
abstract: The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis.
authors.affiliation: Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610-0424, USA.
authors.forename: Cindy A
authors.initials: CA
authors.lastname: Capestany
authors.forename: Masae
authors.initials: M
authors.lastname: Kuboniwa
authors.forename: Il-Young
authors.initials: IY
authors.lastname: Jung
authors.forename: Yoonsuk
authors.initials: Y
authors.lastname: Park
authors.forename: Gena D
authors.initials: GD
authors.lastname: Tribble
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Lamont
mesh_terms: D001426:Bacterial Proteins / Q000502:physiology*; D018441:Biofilms / Q000254:growth & development*; D016966:Porphyromonas gingivalis / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; C069761:internalin protein, Bacteria