title: Three-dimensional optical coherence tomographic findings in central serous chorioretinopathy.
abstract: OBJECTIVE
  The purpose of this study was to evaluate three-dimensional optical coherence tomographic findings at the leakage point on fluorescein angiography in central serous chorioretinopathy (CSC) with OCT-ophthalmoscope.
  
  
  METHODS
  Twenty-seven eyes of 26 patients (23 men, three women; mean age, 50 years; range, 30-72) diagnosed with CSC were examined with OCT-ophthalmoscope, and transverse and longitudinal images were compared with fundus and fluorescein angiography findings.
  
  
  RESULTS
  Transverse images (C-scan) clearly showed serous retinal detachment in all eyes and irregular lesions in retinal pigment epithelium (RPE) in 26 of 27 eyes (96%). These results agreed with the location of lesions in areas of fluorescein dye leakage on fluorescein angiography. Longitudinal images (B-scan) of irregular RPE lesions in transverse images showed RPE detachment (PED) in 17 eyes (63%), small protrusion of the RPE layer in five eyes (19%), and rough RPE layer in four eyes (15%).
  
  
  CONCLUSIONS
  OCT-ophthalmoscope detects morphologic changes easily and noninvasively at the point of dye leakage in eyes with CSC.
authors.affiliation: Department of Ophthalmology, Osaka University, Graduate School of Medicine, Room E7, 2-2 Yamadaoka Suita, Osaka, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Mitarai
authors.forename: Fumi
authors.initials: F
authors.lastname: Gomi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Tano
mesh_terms: D000328:Adult; D000368:Aged; D002199:Capillary Permeability; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012164:Retinal Diseases / Q000175:diagnosis*; D044967:Serum; D041623:Tomography, Optical Coherence