title: A primary follicular lymphoma of the duodenum treated successfully with radiation therapy.
abstract: A 48-year-old man was admitted to our hospital because of repeated episodes of epigastralgia. Endoscopy showed multiple whitish granules extending from the 2nd to 3rd portion of the duodenum. Biopsy specimens showed well circumscribed follicles with a monotonous population of predominantly small cleaved cells that were positive for CD20, CD10 and BCL2, but negative for CD5. A full staging study showed no abnormalities. The tumor was finally diagnosed according to the WHO classification as a stage I follicular lymphoma (FL), grade 1, of the duodenum and subsequently received irradiation to the involved area. After 3 years of followup, he is still in complete remission. Because FL arising in the duodenum has recently reported with increasing frequency, patients with multiple granules in the duodenum should be examined carefully.
authors.affiliation: Department of Gastroenterology and Hepatology, Niigata University, Graduate School of Medical and Dental Sciences, Asahimachi-dori.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Takamura
authors.forename: Rintaro
authors.initials: R
authors.lastname: Narisawa
authors.forename: Yudzuru
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Junji
authors.initials: J
authors.lastname: Yokoyama
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Fukuhara
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kawai
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamagiwa
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Sato
authors.forename: Yasunobu
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Sugimura
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ichida
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Aoyagi
mesh_terms: D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D008224:Lymphoma, Follicular / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage