title: Medullary sponge kidney associated with distal renal tubular acidosis in a 5-year-old girl.
abstract: BACKGROUND
  Medullary sponge kidney (MSK) is characterized by cystic dilatation of the inner medullary collecting ducts, which causes the kidneys to resemble a sponge.
  
  
  METHODS
  Although distal renal tubular acidosis (dRTA) is commonly observed in patients with MSK, we report a 5-year-old girl with MSK who had features of both dRTA (nephrocalcinosis, hypercalciuria, hypocitraturia) and proximal tubular dysfunction (hyperuricosuria, impaired tubular phosphate reabsorption and proteinuria).
  
  
  CONCLUSIONS
  Metabolic acidosis, hypercalciuria, hypocitraturia, tubular phosphate reabsorption and growth retardation in the patient improved with alkali therapy.
authors.affiliation: Department of Pediatrics, Dokuz Eylül University, Inciralti, Izmir, Turkey.
authors.forename: Belde
authors.initials: B
authors.lastname: Kasap
authors.forename: Alper
authors.initials: A
authors.lastname: Soylu
authors.forename: Oğuz
authors.initials: O
authors.lastname: Oren
authors.forename: Mehmet
authors.initials: M
authors.lastname: Türkmen
authors.forename: Salih
authors.initials: S
authors.lastname: Kavukçu
mesh_terms: D000141:Acidosis, Renal Tubular / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D015415:Biomarkers / Q000097:blood / Q000652:urine; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007686:Kidney Tubules, Distal / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D007687:Kidney Tubules, Proximal / Q000473:pathology; D007691:Medullary Sponge Kidney / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D009397:Nephrocalcinosis / Q000209:etiology / Q000473:pathology; D018084:Ultrasonography, Interventional; D014567:Urography
chemical_list: D015415:Biomarkers