title: Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis.
abstract: OBJECTIVE
  To report the clinical and optical coherence tomography features of spherical deposits associated with recurrent toxoplasmic chorioretinitis.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  Atypical, 100 microm to 150 microm, greyish deposits appeared along retinal arteries and veins as well as on the vitreoretinal interface in the macula of a 44-year-old Caucasian woman while she was being treated for recurrent toxoplasmic chorioretinitis with antiparasitic drugs and subconjunctival injection of betamethasone. They disappeared progressively with the systemic use of corticosteroids. Their clinical course was nicely documented by optical coherence tomography.
  
  
  CONCLUSIONS
  Greyish spherical deposits on the vitreoretinal interface have been previously described as inflammatory reactions in asymptomatic human T-lymphotropic virus type I (HTLV-1) carriers and in patients with HTLV-1-associated uveitis. For the first time, optical coherence tomography (OCT) provided clinical correlation of this unusual presentation of toxoplasmic chorioretinitis.
authors.affiliation: Department of Ophthalmology, Université Catholique de Louvain, Cliniques Universitaires St-Luc, Avenue Hippocrate, 1200 Brussels, Belgium. ann-pascale.guagnini@ofta.ucl.ac.be
authors.forename: Ann-Pascale
authors.initials: AP
authors.lastname: Guagnini
authors.forename: Patrick
authors.initials: P
authors.lastname: De Potter
authors.forename: Laurent
authors.initials: L
authors.lastname: Levecq
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kozyreff
mesh_terms: D000328:Adult; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001623:Betamethasone / Q000627:therapeutic use; D002825:Chorioretinitis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D012160:Retina / Q000473:pathology*; D013411:Sulfadiazine / Q000627:therapeutic use; D041623:Tomography, Optical Coherence; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D014822:Vitreous Body / Q000473:pathology*
chemical_list: D000981:Antiprotozoal Agents; D005938:Glucocorticoids; D013411:Sulfadiazine; D001623:Betamethasone; D011739:Pyrimethamine