title: Afzeliixanthones A and B, two new prenylated xanthones from Garcinia afzelii ENGL. (Guttiferae).
abstract: Two new prenylated xanthones, afzeliixanthones A (1) and B (2), together with three known xanthones (3-5) and two phytosterols, beta-sitosterol and stigmasterol, were isolated from the CH2Cl2/MeOH (1:1) extract of the stem bark of Garcinia afzelii ENGL. collected in the South West Province of Cameroon. Structures were mainly established using one and two-dimensional NMR and mass spectroscopies. The antioxidant activities of the crude extracts as well as the new compounds (1) and (2) were evaluated.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Douala, Cameroon. akamdemfr@yahoo.fr
authors.forename: Alain François
authors.initials: AF
authors.lastname: Kamdem Waffo
authors.forename: Dulcie
authors.initials: D
authors.lastname: Mulholland
authors.forename: Jean Duplex
authors.initials: JD
authors.lastname: Wansi
authors.forename: Luc Meva'a
authors.initials: LM
authors.lastname: Mbaze
authors.forename: Robert
authors.initials: R
authors.lastname: Powo
authors.forename: Theophile Ngando
authors.initials: TN
authors.lastname: Mpondo
authors.forename: Zacharias Tanee
authors.initials: ZT
authors.lastname: Fomum
authors.forename: Wilfried
authors.initials: W
authors.lastname: König
authors.forename: Augustin Ephrem
authors.initials: AE
authors.lastname: Nkengfack
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D029760:Garcinia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013265:Stigmasterol / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D012855:Sitosterols; D044004:Xanthones; C511005:afzeliixanthone A; C511006:afzeliixanthone B; C025473:gamma-sitosterol; D013265:Stigmasterol