title: Catalytic enantioselective O-H insertion reactions.
abstract: The first effective method for catalytic enantioselective insertions into O-H bonds has been developed. Specifically, a copper/bisazaferrocene catalyst couples alcohols such as 2-trimethylsilylethanol with alpha-aryl-alpha-diazo esters in high yield and good ee.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Maier
authors.forename: Gregory C
authors.initials: GC
authors.lastname: Fu
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry*; D004987:Ethers / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D004952:Esters; D004987:Ethers