title: Well-defined lactose-containing polymer grafted onto silica particles.
abstract: Reversible addition-fragmentation chain transfer (RAFT) polymerization of 2-O-meth-acryloyloxyethoxyl-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-(1-4)-2,3,6-tri-O-acetyl-beta-D-glucopyranoside (MAEL) was performed directly in CHCl3 solutions using cumyl dithiobenzoate (CDB) as the chain transfer agent to give well-defined glycopolymers. The chemical composition and structure of the glycopolymer were characterized by 1HNMR, FTIR, and SEC. The living glycopolymer chains were subsequently grafted onto gamma-methacryloxypropyl-trimethoxy (MPTMS) modified silica particles. The acetyl groups of the poly(MAEL) grafted onto the silica gel particles were converted to the hydroxyl groups with CH3ONa/CH3OH, thus obtaining silica gel particles modified with well-defined lactose-carrying polymer.
authors.affiliation: Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education of China, China. tyguo@nankai.edu.cn
authors.forename: Tian-Ying
authors.initials: TY
authors.lastname: Guo
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Jing-Wei
authors.initials: JW
authors.lastname: Zhu
authors.forename: Mou-Dao
authors.initials: MD
authors.lastname: Song
authors.forename: Bang-Hua
authors.initials: BH
authors.lastname: Zhang
mesh_terms: D001565:Benzoates / Q000737:chemistry; D002236:Carbohydrate Conformation; D007785:Lactose / Q000031:analogs & derivatives / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: C511371:2-O-methacryloyloxyethoxyl-(2,3,4,6-tetra-O-acetylgalactopyranosyl)-(1-4)-2,3,6-tri-O-acetylglucopyranoside; D001565:Benzoates; D008689:Methacrylates; D011108:Polymers; D012821:Silanes; C511372:cumyl dithiobenzoate; C017492:methacryloxypropyltrimethoxysilane; D012822:Silicon Dioxide; D007785:Lactose