Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis.
OBJECTIVE
To report the clinical and optical coherence tomography features of spherical deposits associated with recurrent toxoplasmic chorioretinitis.


METHODS
Case report.


RESULTS
Atypical, 100 microm to 150 microm, greyish deposits appeared along retinal arteries and veins as well as on the vitreoretinal interface in the macula of a 44-year-old Caucasian woman while she was being treated for recurrent toxoplasmic chorioretinitis with antiparasitic drugs and subconjunctival injection of betamethasone. They disappeared progressively with the systemic use of corticosteroids. Their clinical course was nicely documented by optical coherence tomography.


CONCLUSIONS
Greyish spherical deposits on the vitreoretinal interface have been previously described as inflammatory reactions in asymptomatic human T-lymphotropic virus type I (HTLV-1) carriers and in patients with HTLV-1-associated uveitis. For the first time, optical coherence tomography (OCT) provided clinical correlation of this unusual presentation of toxoplasmic chorioretinitis.
Guagnini
Ann-Pascale
AP
Department of Ophthalmology, Université Catholique de Louvain, Cliniques Universitaires St-Luc, Avenue Hippocrate, 1200 Brussels, Belgium. ann-pascale.guagnini@ofta.ucl.ac.be
De Potter
Patrick
P
Levecq
Laurent
L
Kozyreff
Alexandra
A
D000328:Adult; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001623:Betamethasone / Q000627:therapeutic use; D002825:Chorioretinitis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D012160:Retina / Q000473:pathology*; D013411:Sulfadiazine / Q000627:therapeutic use; D041623:Tomography, Optical Coherence; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D014822:Vitreous Body / Q000473:pathology*
D000981:Antiprotozoal Agents; D005938:Glucocorticoids; D013411:Sulfadiazine; D001623:Betamethasone; D011739:Pyrimethamine