[Linkage analysis of five genes in pigs using radiation hybrid clone panel].
RH (radiation hybrid) has proved to be an effective method in constructing human genome maps (including ESTs, STSs and microsatellites). In this study, based on the information of five human genes (FMR1, IDS, FATE, BGN, F8A) on the X chromosome, the linkage relationship of these five genes in pigs were analyzed by a panel of 96 radiation hybrid cell lines. The results showed that FMR1, IDS, FATE, BGN, F8A were in the same linkage group, when LOD was set at 4. When LOD was set at 5, FMR1 and IDS were in the one group, FATE and BGN in the other group, and F8A was in a group by itself.
Li
Yin-Xia
YX
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Hu
Yan-Biao
YB
Chen
Jie
J
Xu
Yin-Xue
YX
Liu
Hong-Lin
HL
Jiang
Zhi-Hua
ZH
D000818:Animals; D002478:Cells, Cultured; D004268:DNA-Binding Proteins / Q000235:genetics*; D020224:Expressed Sequence Tags / Q000378:metabolism; D008040:Genetic Linkage; D006801:Humans; D006822:Hybrid Cells; D018895:Microsatellite Repeats / Q000235:genetics*; D021101:Radiation Hybrid Mapping / Q000379:methods*; D016324:Sequence Tagged Sites; D034421:Sus scrofa / Q000235:genetics*; D013552:Swine; D014157:Transcription Factors / Q000235:genetics*
D004268:DNA-Binding Proteins; C449758:FATE1 protein, human; D014157:Transcription Factors