title: Leishmanicidal activity of Pycnoporus sanguineus.
abstract: In the search for antiparasite compounds from the Colombian flora, an active compound against Leishmania (Viannia) panamensis amastigotes was isolated from the fungi Pycnoporus sanguineus. The structural elucid-ation was achieved with spectroscopic methods ((1)H and (13)C NMR and MS). This compound was identified as ergosterol 5,8-endoperoxide.
authors.affiliation: Grupo de Química Orgánica de Productos Naturales-SIU, Universidad de Antioquia, P.O. Box 1226, Medellín-Colombia.
authors.forename: Edwin
authors.initials: E
authors.lastname: Correa
authors.forename: Diana
authors.initials: D
authors.lastname: Cardona
authors.forename: Winston
authors.initials: W
authors.lastname: Quiñones
authors.forename: Fernando
authors.initials: F
authors.lastname: Torres
authors.forename: Ana E
authors.initials: AE
authors.lastname: Franco
authors.forename: Ivan D
authors.initials: ID
authors.lastname: Vélez
authors.forename: Sara
authors.initials: S
authors.lastname: Robledo
authors.forename: Fernando
authors.initials: F
authors.lastname: Echeverri
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000302:isolation & purification*; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D018334:Leishmania guyanensis; D011124:Polyporaceae / Q000737:chemistry* / Q000254:growth & development
chemical_list: D000981:Antiprotozoal Agents; C036071:ergosterol-5,8-peroxide; D004875:Ergosterol