title: [New strategies in multiple organ dysfunction syndrome therapy for sepsis].
abstract: Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids), all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient.
authors.forename: Maja
authors.initials: M
authors.lastname: Surbatović
authors.forename: Sonja
authors.initials: S
authors.lastname: Radaković
authors.forename: Krsta
authors.initials: K
authors.lastname: Jovanović
authors.forename: Predrag
authors.initials: P
authors.lastname: Romić
mesh_terms: D006801:Humans; D009102:Multiple Organ Failure / Q000209:etiology / Q000628:therapy*; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000628:therapy*