title: [Predictive biochemical indicators of a postlaryngectomy pharyngocutaneous fistula: a clinical study].
abstract: The aim of this clinical study was to determinate biochemical predictor indicators of postlaryngectomy pharyngocutaneous fistula.
  
  
  METHODS
  We have studied 100 patients with T2- 4 a laryngeal and piryform sinus carcinoma who underwent a laryngectomy. All patients were ASA 2-3. We studied serum albumin, protein serum level, cholesterol and lymphocites in each patient. These variables underwent statistical analysis (p < 0.05).
  
  
  RESULTS
  19% of the patients developed a postlaryngectomy pharyngocutaneous fistula, with a long-stay of 25 days vs. 10 days of stay in patients without postlaryngectomy pharyngocutaneous fistula. 7 postlaryngectomy pharyngocutaneous fistula needed surgical repair. Low serum albumin (< 3.5 g/dL) and a low level of serum proteins (< 6.5 g/dL) were predictive indicators of postlaryngectomy pharyngocutaneous fistula (p < 0.05).
  
  
  CONCLUSIONS
  Our results suggest that a low-level of serum proteins and albumin are predictive clinical parameters of postlaryngeal pharyngocutaneous fistula.
authors.affiliation: Servicio ORL, Hospital del Bierzo, Ponferrada, León. cmvillares@hotmail.com
authors.forename: C
authors.initials: C
authors.lastname: Martín Villares
authors.forename: P
authors.initials: P
authors.lastname: Pomar
authors.forename: M C
authors.initials: MC
authors.lastname: Iglesias
authors.forename: J
authors.initials: J
authors.lastname: San Román
authors.forename: M
authors.initials: M
authors.lastname: Fernández Pello
authors.forename: P
authors.initials: P
authors.lastname: Aldama
authors.forename: M J
authors.initials: MJ
authors.lastname: González Gimeno
authors.forename: M
authors.initials: M
authors.lastname: Tapia
mesh_terms: D015415:Biomarkers / Q000097:blood; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D017577:Cutaneous Fistula / Q000097:blood* / Q000209:etiology*; D005402:Fistula / Q000097:blood* / Q000209:etiology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery; D007825:Laryngectomy / Q000009:adverse effects*; D010608:Pharyngeal Diseases / Q000097:blood* / Q000209:etiology*; D011446:Prospective Studies
chemical_list: D015415:Biomarkers