A new active compound from Centaurea species.
The extract containing sesquiterpene lactones of Centaurea iberica (Asteraceae) isolated was separated and a steroidal compound, which is stigmast-1,5-dien-3beta-ol, was purified. The chemical structure was established based on spectroscopic data (UV, IR, MS, 1H NMR, 13C NMR). Both the extract and the compound showed significant antioxidant and antimicrobial activities.
Dumlu
Melek U
MU
Marmara University, Faculty of Pharmacy, Department of Pharmacognosy, Istanbul, Turkey. melekulusoylu@hotmail.com
Gürkan
Elcin
E
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology*; D001156:Artemia / Q000187:drug effects; D031179:Centaurea / Q000737:chemistry*; D010084:Oxidation-Reduction; D010578:Petroleum; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification
D000935:Antifungal Agents; D000975:Antioxidants; D010578:Petroleum; D010936:Plant Extracts; D013256:Steroids