title: Hyosgerin, a new optically active coumarinolignan, from the seeds of Hyoscyamus niger.
abstract: Hyosgerin, a new optically active coumarinolignan, has been isolated and characterized along with three other coumarinolignans, venkatasin, cleomiscosin A and cleomiscosin B, from the seeds of Hyoscyamus niger L. The structure was determined on the basis of spectroscopic analysis and chemical conversion. The optical properties and absolute stereochemistry of these coumarinolignans have also been studied and discussed.
authors.affiliation: Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. sajeli1@rediffmail.com
authors.forename: Begum
authors.initials: B
authors.lastname: Sajeli
authors.forename: Mahendra
authors.initials: M
authors.lastname: Sahai
authors.forename: Roderich
authors.initials: R
authors.lastname: Suessmuth
authors.forename: Teigo
authors.initials: T
authors.lastname: Asai
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Hara
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Fujimoto
mesh_terms: D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004146:Dioxanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D032304:Hyoscyamus / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D009904:Optical Rotation; D010946:Plants, Medicinal; D012639:Seeds / Q000737:chemistry*; D013057:Spectrum Analysis; D013237:Stereoisomerism
chemical_list: D003374:Coumarins; D004146:Dioxanes; D017705:Lignans; C511093:hyosgerin; C041934:cleomiscosin A