title: Evidence for a dysfunction of left posterior reading areas in German dyslexic readers.
abstract: The brain activity during a sentence reading task and a visual control task was examined with fMRI in 13 German dyslexic readers and 15 age-matched fluent readers (age: 14-16 years). These participants came from a longitudinal study and the dyslexic readers exhibited a persistent reading fluency deficit from early on. For the first time with German dyslexic readers, and in correspondence with the majority of functional imaging studies, we found reduced dyslexic activation in the left occipitotemporal cortex and in a small region of the left supramarginal gyrus. Enhanced activation was found in left inferior frontal and subcortical regions.
authors.affiliation: Department of Psychology & Center for Neurocognitive Research, University of Salzburg, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Kronbichler
authors.forename: Florian
authors.initials: F
authors.lastname: Hutzler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Staffen
authors.forename: Alois
authors.initials: A
authors.lastname: Mair
authors.forename: Gunther
authors.initials: G
authors.lastname: Ladurner
authors.forename: Heinz
authors.initials: H
authors.lastname: Wimmer
mesh_terms: D000293:Adolescent; D001931:Brain Mapping; D016022:Case-Control Studies; D002540:Cerebral Cortex / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D004410:Dyslexia / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D005858:Germany; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation / Q000379:methods; D011932:Reading; D012660:Semantics
chemical_list: D010100:Oxygen