title: A case of primary biliary cirrhosis complicated by Behçet's disease and palmoplantar pustulosis.
abstract: A 46-year-old woman was diagnosed with palmoplantar pustulosis (PPP) at the Department of Dermatology, Fukushima Medical University Hospital in 2000, and was treated with ointment. However, because liver dysfunction developed in 2003, she was referred to our department, where primary biliary cirrhosis (PBC) was also diagnosed on the basis of clinical findings. One year later, at the age of 49, she developed manifestations of Behçet's disease (BD), including erythema nodosum in the lower extremities. Because she had a history of uveitis, recurrent oral ulceration was present, and the HLA typing was positive for B51, BD was additionally diagnosed. Liver function normalized within three months of the start of treatment with ursodesoxycholic acid (UDCA). This is the first case of PBC associated with BD and PPP.
authors.affiliation: Department of Internal Medicine II, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan. haru-i@fmu.ac.jp
authors.forename: Haruyo
authors.initials: H
authors.lastname: Iwadate
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
authors.forename: Hironobu
authors.initials: H
authors.lastname: Saito
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Rai
authors.forename: Junko
authors.initials: J
authors.lastname: Takiguchi
authors.forename: Tomomi
authors.initials: T
authors.lastname: Sasajima
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Watanabe
authors.forename: Yukio
authors.initials: Y
authors.lastname: Sato
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D011565:Psoriasis / Q000150:complications*