Gold(I)-catalyzed stereoselective formation of functionalized 2,5-dihydrofurans.
[reaction: see text] A study concerning the gold(I)-catalyzed rearrangement of butynediol monobenzoates into functionalized 2,5-dihydrofurans is described. The mild reaction conditions employed allow the efficient and rapid stereoselective synthesis of a variety of 2,5-dihydrofurans via a sequence of two gold(I)-catalyzed isomerization steps.
Buzas
Andrea
A
Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique, Ecole Polytechnique, 91128 Palaiseau, France.
Istrate
Florin
F
Gagosz
Fabien
F