title: Cutaneous leukocytoclastic vasculitis in a child with interleukin-12 receptor beta-1 deficiency.
abstract: We report a patient with complete interleukin-12 receptor beta-1 deficiency associated with cutaneous leukocytoclastic vasculitis. The patient experienced Bacille Calmette Guérin, Mycobacterium chelonae, and Salmonella enteritidis infection. Vasculitis affecting both small arteries and postcapillary venules due to deposition of immune complexes was probably caused by S. enteritidis and/or M. chelonae infection.
authors.affiliation: Department of Pediatrics, Ege University Medical School, Izmir, Turkey. neci@med.ege.edu.tr
authors.forename: Necil
authors.initials: N
authors.lastname: Kutukculer
authors.forename: Ferah
authors.initials: F
authors.lastname: Genel
authors.forename: Guzide
authors.initials: G
authors.lastname: Aksu
authors.forename: Bulent
authors.initials: B
authors.lastname: Karapinar
authors.forename: Can
authors.initials: C
authors.lastname: Ozturk
authors.forename: Cengiz
authors.initials: C
authors.lastname: Cavusoglu
authors.forename: Jean-Laurent
authors.initials: JL
authors.lastname: Casanova
authors.forename: Claire
authors.initials: C
authors.lastname: Fieschi
mesh_terms: D000818:Animals; D002417:Cattle; D002648:Child; D003241:Consanguinity; D005260:Female; D006801:Humans; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy; D009163:Mycobacterium bovis / Q000302:isolation & purification; D016926:Mycobacterium chelonae / Q000302:isolation & purification; D016659:Psoas Abscess / Q000382:microbiology; D018123:Receptors, Interleukin / Q000172:deficiency*; D053707:Receptors, Interleukin-12; D012480:Salmonella Infections / Q000175:diagnosis / Q000188:drug therapy; D012477:Salmonella enteritidis / Q000302:isolation & purification; D013163:Splenomegaly / Q000601:surgery; D014380:Tuberculosis, Bovine / Q000175:diagnosis / Q000188:drug therapy; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D018123:Receptors, Interleukin; D053707:Receptors, Interleukin-12