title: Proliferative verrucous leukoplakia and field cancerization: report of a case.
abstract: Proliferative verrucous leukoplakia (PVL) is a multi-focal oral pre-malignant lesion, proliferative in nature, with a tendency to recur despite adequate therapy, and a high rate of malignant transformation. The field cancerization phenomenon may explain the characteristic behaviour of PVL. A case of PVL is presented and the field cancerization concept is discussed.
authors.affiliation: Periodontology and Oral Medicine, Medical University of Southern Africa, South Africa. lfeller@medunsa.ac.za
authors.forename: Liviu
authors.initials: L
authors.lastname: Feller
authors.forename: Neil H
authors.initials: NH
authors.lastname: Wood
authors.forename: Erich J
authors.initials: EJ
authors.lastname: Raubenheimer
mesh_terms: D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D006801:Humans; D007972:Leukoplakia, Oral / Q000209:etiology / Q000473:pathology*; D008297:Male; D009062:Mouth Neoplasms / Q000209:etiology / Q000473:pathology*; D010212:Papilloma / Q000209:etiology / Q000473:pathology*; D011230:Precancerous Conditions / Q000209:etiology / Q000473:pathology*; D012907:Smoking / Q000009:adverse effects