title: Successful delivery after vaginal radical trachelectomy for invasive uterine cervical cancer.
abstract: A 32-year-old Japanese woman was diagnosed as having stage Ib1 adenocarcinoma by diagnostic laser conization at a local hospital. She was admitted to our hospital for fertility-sparing treatment. A radical trachelectomy (RT) was performed using the laparoscopic vaginal procedure. The procedure was started with a laparoscopic pelvic lymphadenectomy. As the lymph nodes were tumor free, RT was carried out transvaginally. The excised uterine cervix and lymph nodes were pathologically negative for cancer. Eight months after the operation, the patient became pregnant without any artificial reproduction techniques. At 17 weeks of gestation, she was admitted to our hospital again for a threatened abortion. Continuous tocolytic treatment with ritodrine and daily administration of a granulocyte elastase inhibitor vaginal suppository were given. At 32 weeks of gestation, she underwent emergency cesarean section because of sudden premature rupture of the membranes. A girl weighing 1991 g was delivered, with Apgar scores of 7 and 8 at 1 and 5 min, respectively. Both the mother and the baby were discharged without trouble. This is the first successful case in Japan of delivery after vaginal RT for invasive uterine cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology, Sapporo Medical University, School of Medicine, Minami 1-jo, Nishi 17-chome, Sapporo, Hokkaido 060-8543, Japan. ishioka@sapmed.ac.jp
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Ishioka
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Endo
authors.forename: Takuhiro
authors.initials: T
authors.lastname: Hayashi
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Kitajima
authors.forename: Masaki
authors.initials: M
authors.lastname: Sugimura
authors.forename: Satoru
authors.initials: S
authors.lastname: Sagae
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Saito
mesh_terms: D000328:Adult; D002585:Cesarean Section; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000601:surgery; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D010535:Laparoscopy; D011247:Pregnancy; D011256:Pregnancy Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*