title: Auxiliary partial orthotopic living donor liver transplantation in a patient with alcoholic liver cirrhosis to overcome donor steatosis.
abstract: The efficacy of auxiliary partial orthotopic liver transplantation (APOLT) to overcome the problems associated with a markedly steatotic graft in a living donor has not been fully explored. We have recently performed APOLT in a patient with alcoholic liver disease, where the only potential candidate donor was affected by 50% macrovesicular steatosis and 30% microvesicular steatosis. The recipient's left liver was resected and the donor's left liver, corresponding to a 0.46% graft-to-recipient weight ratio, was orthotopically transplanted. The postoperative course of this patient was uneventful, except for a transient large amount of ascites. Native liver volume in the recipient serially decreased, and the volume of the graft serially increased after transplantation. Four months after transplantation, the donor and recipient are doing well with a normal liver function. In conclusion, APOLT may be a feasible solution for a markedly steatotic living donor graft in patients with alcoholic liver disease.
authors.affiliation: Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jai Young
authors.initials: JY
authors.lastname: Cho
authors.forename: Kyung-Suk
authors.initials: KS
authors.lastname: Suh
authors.forename: Choon Hyuck
authors.initials: CH
authors.lastname: Kwon
authors.forename: Nam-Joon
authors.initials: NJ
authors.lastname: Yi
authors.forename: Min A
authors.initials: MA
authors.lastname: Kim
authors.forename: Min Aon
authors.initials: MA
authors.lastname: Kim
authors.forename: Ja-June
authors.initials: JJ
authors.lastname: Jang
authors.forename: Kyung Won
authors.initials: KW
authors.lastname: Minn
authors.forename: Kuhn Uk
authors.initials: KU
authors.lastname: Lee
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000418:Albumins / Q000096:biosynthesis; D001219:Aspartate Aminotransferases / Q000097:blood; D001646:Bile / Q000378:metabolism; D001663:Bilirubin / Q000097:blood; D005234:Fatty Liver / Q000628:therapy*; D006085:Graft Survival; D006801:Humans; D008099:Liver / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000628:therapy*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged
chemical_list: D000418:Albumins; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin