[Cutaneous side effects of a long-term treatment by hydroxyurea].
Hydroxyurea is an antitumour agent used most commonly to treat myeloproliferative disorders. We present a clinical observation illustrating different cutaneous side effects susceptible to occur during a long-term treatment by hydroxyurea : leg ulceration, oral ulcer and spinocellular carcinoma. This clinical observation is completed by a review of the literature published on the cutaneous side effects of hydroxyurea treatment.
Steels
E
E
Service de Dermatologie, Hôpital Erasme, CHIREC, Site Edith Cavell.
Heenen
M
M
Germaux
M A
MA
Moens
J P
JP
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002277:Carcinoma / Q000139:chemically induced; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects* / Q000627:therapeutic use; D007871:Leg Ulcer / Q000139:chemically induced*; D008297:Male; D009196:Myeloproliferative Disorders / Q000188:drug therapy; D019226:Oral Ulcer / Q000139:chemically induced*; D012878:Skin Neoplasms / Q000139:chemically induced
D000970:Antineoplastic Agents; D006918:Hydroxyurea