title: [Intratumor bleomycin-A5 injection under electrolaryngoscope for treatment of large laryngopharyngeal and laryngeal hemangioma].
abstract: OBJECTIVE
  To study the therapeutic effect of bleomycin-A5 injection under eletrolaryngoscope for treatment of large laryngopharyngeal and laryngeal hemangioma.
  
  
  METHODS
  Intratumor bleomycin-A5 injection under eletrolaryngoscope was performed in 18 cases of large laryngopharyngeal and laryngeal hemangioma with surface anaesthesia, for totally 7 to 14 (mean 10.2) injections in each case.
  
  
  RESULTS
  Twelve patients were cured and 6 showed obvious improvement. Follow-up of the patients for over one year found no recurrence of the hemangioma.
  
  
  CONCLUSIONS
  Bleomycin-A5 injection is a minimal invasive procedure for treatment of large laryngopharyngeal and laryngeal hemangioma, causing less pain and better preserving the laryngeal function without the necessity of tracheotomy.
authors.affiliation: Department of Otolaryngology, 118 Hospital of PLA, Wenzhou 325000, China. huangyideng@sohu.com
authors.forename: Yi-deng
authors.initials: YD
authors.lastname: Huang
authors.forename: Jian-fu
authors.initials: JF
authors.lastname: Chen
authors.forename: Si-wen
authors.initials: SW
authors.lastname: Xia
authors.forename: Zi-xi
authors.initials: ZX
authors.lastname: Huang
authors.forename: Guang-yao
authors.initials: GY
authors.lastname: Wang
authors.forename: Xing-hua
authors.initials: XH
authors.lastname: Luo
authors.forename: Chun-juan
authors.initials: CJ
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D001761:Bleomycin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D020704:Laryngoscopes; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000188:drug therapy*
chemical_list: D000903:Antibiotics, Antineoplastic; D001761:Bleomycin; C025703:bleomycetin