[Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy].
OBJECTIVE
Gauging the acute effect of Percutaneous transluminal septal myocardial ablation (PTSMA) as a treatment for hypertrophic obstructive cardiomyopathy (HOCM).


METHODS
PTSMA was performed in 52 patients with symptomatic HOCM [mean age (44.7 +/- 11.9), male 38, female 14]. All patients had echocardiography performed prior to the procedure, 3-7 days post-PTSMA.


RESULTS
Procedure success was achieved in 41 patients, success rate was 78.8%. The average left ventricular outflow tract (LVOT) gradient was (92.64 +/- 38.69) mm Hg before the procedure, and (51.79 +/- 38.99) mm Hg after the procedure (P < 0.001). The thickness of interventricular septum (IVS) was (22.96 +/- 5.15) mm before the procedure and became (21.27 +/- 4.64) mm 3-7 days post-PTSMA (P < 0.05). The incidence of right bundle branch block development post-PTSMA was 15.38% (> 48 h), and one patient (1.92%) had complete heart block. Two patients died.


CONCLUSIONS
PTSMA is an effective non-surgical procedure for symptomatic patients with HOCM because of its low risk and its significant hemodynamic and echocardiographic improvement.
Qiao
Shu-bin
SB
Department of Cardiology, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100037, China. sbqiao@hotmail.com.cn
Gao
Run-lin
RL
You
Shi-jie
SJ
Yuan
Jian-song
JS
Chen
Ji-lin
JL
Yang
Yue-jin
YJ
D000328:Adult; D000800:Angioplasty, Balloon; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000601:surgery* / Q000628:therapy; D017115:Catheter Ablation / Q000379:methods*; D004452:Echocardiography; D005260:Female; D006346:Heart Septum / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome