New butyrylcholinesterase inhibitory triterpenes from Salvia santolinifolia.
Slavins A (1) and B (2), the new amyrin type triterpenes, have been isolated from the chloroform soluble fraction of Salvia santolinifolia and assigned structures on the basis of spectral studies including 2D NMR. Both the compounds displayed inhibitory potential against the enzyme butyrylcholinesterase.
Mehmood
Sajid
S
Pharmaceutical Research Centre, PCSIR Laboratories Complex, Karachi, Pakistan.
Riaz
Naheed
N
Nawaz
Sarfraz Ahmed
SA
Afza
Nighat
N
Malik
Abdul
A
Choudhary
Muhammad Iqbal
MI
D002091:Butyrylcholinesterase; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D027544:Salvia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D002800:Cholinesterase Inhibitors; D014315:Triterpenes; D002091:Butyrylcholinesterase