[Purification of total flavones from Morus alba L.by macroporous adsorbents and kinetic model for the process].
To establish the separation and purification technology for the total flavones from Morus alba L.(MTF), and present a kinetic model for this process.



Three types of macroporous adsorbents were tested to separate and purify MTF, and to evaluated by adsorption capacity, elution ratio and product purity. The curves of dynamic adsorption-elution process was plotted and the kinetic equations were presented.



Among three types of macroporous adsorbents, the NKA-9 type showed better property with the adsorption capacity of 43.4 mg.g(-1)and the elution ratio of 98.2%. The purity of MTF product reached to 58.2 % in the technological conditions following: extract sample concentration of 20 mg.ml(-1), 6 times washing water and elution reagent of 70% ethanol. The adsorbent could be used for 4 times repeatedly. The kinetic equation was y=u(1 - e(-kx)).



The NKA-9 type of macroporous absorbent is suitable to purify the MTF.
Chen
Jing-jing
JJ
College of Pharmaceutical Science, Zhejiang University, Hangzhou 310031, China.
Li
Xiang-rong
XR
Fang
Xiao
X
D000327:Adsorption; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification* / Q000493:pharmacokinetics; D047309:Flavones / Q000302:isolation & purification* / Q000493:pharmacokinetics; D031625:Morus / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D016062:Porosity; D013678:Technology, Pharmaceutical
D004365:Drugs, Chinese Herbal; D047309:Flavones