title: [Specifics of therapy of tubal infertility in patients with endometriosis].
abstract: Our purpose was to define the best way of treating tubal infertility caused by endometriosis. We have studied 24 patients with tubal infertility caused by endometriosis; the etiology has been laparoscopically established in the 2nd Clinic of Obstetrics and Gynecology Iaşi. The endometriosis score (r-AFS) was used to establish the therapy. We performed laparoscopic treatment when endometriosis was visible. Postoperative medical therapy (Diphereline, 3 months) was indicated; patients with ,,unpigmented endometriosis" received the same medical therapy. The rate of pregnancies in patients that had benefit of combined therapy: surgical and medical (n=9) was superior (44.4%) to that obtained in patients that were only surgical treated (n=15): 26.6% (Spearman correlation--0.6595, p < 0.0012). Endometriosis is an important etiological factor in female infertility. The pathway is mechanic as well as chemical and it justifies the combined therapy. There are better results, as fertility prognosis in patients with endometriosis that receive both, surgical and medical therapy.
authors.affiliation: Univesitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica a II-a Obstetrică-Ginecologie.
authors.forename: Simina
authors.initials: S
authors.lastname: Vegheş
authors.forename: Ivona
authors.initials: I
authors.lastname: Lupaşcu
authors.forename: Cristina
authors.initials: C
authors.lastname: David
authors.forename: Valeria
authors.initials: V
authors.lastname: Vişan
authors.forename: Veronica
authors.initials: V
authors.lastname: Vasiliu
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D004715:Endometriosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D005184:Fallopian Tube Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D010535:Laparoscopy / Q000379:methods; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal