Depression assessed over 1-year survival in patients with myocardial infarction.
OBJECTIVE
To estimate the prevalence of ICD-10 depression using a self-reported questionnaire and to examine if depression is associated with increased 1-year mortality in patients with myocardial infarction (MI).


METHODS
In total, 763 MI-patients completed the Major Depression Inventory at discharge. Information from hospital notes was collected and patients were followed 1 year for re-admission and mortality through national registries.


RESULTS
Seventy-three patients (9.6%) were depressed at discharge. Depression was not a significant independent predictor of mortality; however, there was a significant trend for increasing mortality with increasing severity of the depressive state (P = 0.028). All mortality among depressed patients was in patients with non-Q-wave infarction.


CONCLUSIONS
Ten per cent of MI-patients fulfilled diagnostic criteria for depression at discharge. There was a significant trend for increasing mortality with increasing severity of the depressive episode. All mortality among depressed patients was seen in patients with non-Q-wave infarction. These findings indicate future studies in selected subgroups of MI-patients.
Sørensen
C
C
The Medical Research Unit, Ringkøbing County, Ringkøbing, Denmark. chs@dadlnet.dk
Brandes
A
A
Hendricks
O
O
Thrane
J
J
Friis-Hasché
E
E
Haghfelt
T
T
Bech
P
P
D000368:Aged; D003710:Demography; D003718:Denmark / Q000453:epidemiology; D003865:Major Depressive Disorder / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality* / Q000534:rehabilitation; D010351:Patient Discharge / Q000706:statistics & numerical data; D015995:Prevalence; D011795:Surveys and Questionnaires; D015996:Survival Rate; D013997:Time Factors