Neuropathic pain: are we out of the woods yet?
Patients suffering from neuropathic pain continue to pose challenges in clinical practice. This descriptive review discusses the continuing debate on the definition and concerns about increasing incidence of neuropathic pain. The clinical features of neuropathic pain are outlined, and the current understanding of the possible mechanisms of neuropathic pain is highlighted. Current management strategies are reviewed, and future advances in our understanding of the mechanisms, accurate clinical diagnosis and more effective treatment strategies are eagerly awaited.
Cavenagh
J
J
Department of Palliative Care, Mater Misericordiae Hospital, Newcastle, New South Wales, Australia. john.cavenagh@mater.health.nsw.gov.au
Good
P
P
Ravenscroft
P
P
D000700:Analgesics / Q000627:therapeutic use*; D002908:Chronic Disease; D016207:Cytokines / Q000009:adverse effects; D006801:Humans; D017628:Microglia / Q000502:physiology; D009422:Nervous System Diseases / Q000150:complications* / Q000503:physiopathology; D009437:Neuralgia / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology
D000700:Analgesics; D016207:Cytokines; D016194:Receptors, N-Methyl-D-Aspartate