title: Pilot study of dynamic cine CT angiography for the evaluation of abdominal aortic aneurysms: implications for endograft treatment.
abstract: OBJECTIVE
  To utilize 40-slice electrocardiographically (ECG)-gated cine computed tomographic angiography (CTA) to characterize normal aortic motion during the cardiac cycle at relevant anatomical landmarks in preoperative abdominal aortic aneurysm (AAA) patients.
  
  
  METHODS
  In 10 consecutive preoperative AAA patients (10 men; mean age 78.8 years, range 69-86), an ECG-gated CTA dataset was acquired on a 40-slice CT scanner using a standard radiation dose. CTA quality was graded and scan time was measured. Pulsatility measurements at multiple relevant anatomical levels were performed in the axial plane. Changes in aortic circumference were determined for both the aortic wall and the luminal diameter.
  
  
  RESULTS
  All 10 CT scans were of good quality. All patients could be scanned in 14 to 33 seconds (mean 21). At each anatomical level measured, there was a 2.2- to 3.4-mm increase in the aortic wall circumference per cardiac cycle. A similar increase was observed in luminal circumference, with a 2.4- to 3.6-mm increase per cycle.
  
  
  CONCLUSIONS
  This study introduces the concept of dynamic cine CTA imaging of aortic motion, providing insight into the pathophysiology of abdominal aortic and iliac pulsations. Patients with AAAs selected for EVAR demonstrate changes in aortic circumference with each cardiac cycle that may have consequences for endograft sizing and future design. The potential for graft migration, intermittent type I endoleak, and poor patient outcome following EVAR can be anticipated. Complex aortic dynamics deserve increased scrutiny in an effort to prevent potential complications.
authors.affiliation: Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands.
authors.forename: Arno
authors.initials: A
authors.lastname: Teutelink
authors.forename: Annemarieke
authors.initials: A
authors.lastname: Rutten
authors.forename: Bart E
authors.initials: BE
authors.lastname: Muhs
authors.forename: Marco
authors.initials: M
authors.lastname: Olree
authors.forename: Joost A
authors.initials: JA
authors.lastname: van Herwaarden
authors.forename: Alexander M
authors.initials: AM
authors.lastname: de Vos
authors.forename: Mathias
authors.initials: M
authors.lastname: Prokop
authors.forename: Frans L
authors.initials: FL
authors.lastname: Moll
authors.forename: Hence J M
authors.initials: HJ
authors.lastname: Verhagen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods*; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D001783:Blood Flow Velocity; D019917:Blood Vessel Prosthesis Implantation; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D010865:Pilot Projects; D011673:Pulsatile Flow; D014057:Tomography, X-Ray Computed