title: [Changes of immunological and cytogenetic indexes in lymphocytes of patients with bacterial endocarditis under the influence of laser therapy and a hyperbaric oxygen therapy].
abstract: The purpose of the present work was the estimation of the therapeutic effect of the soft laser therapy and a hyperbaric oxygen therapy during their inclusion in a therapeutic complex for the treatment of bacterial endocarditis. 30 patients (II group) under our observation have passed the standard basic therapy, and for 45 patients (I group) of different age the intravenous laser and hyperbaric oxygenation were added into the therapeutic complex. The estimation was made by evaluation of immune status and cytogenetic markers before treatment. At the height of disease there was marked immune deficiency, basically at the expense of T-helpers, and also of the B- lymphocyte part. The phagocyte system efficiency indices were decreased. By the admission of patients in the clinic the number cells with aberrations of chromosomes was increased. After the treatment nn the I group of patients there was absolute and relative elevation on the number of T-and B- lymphocytes, T- helpers, also the decrease of leukocytes, T-lymphocyte index, the increase of blast transformation lymphocytes level on mytogen FGA. The phagocytosis was activated, the balanced level of different Ig classes occurred. Number of cells with aberrations of chromosomes sharply decreased, basically at the expense of aneuploidic cells. Obtained results show, that laser therapy and hyperbaric oxygen therapy can be included in the therapeutic complex for the treatment of bacterial endocarditis.
authors.forename: I T
authors.initials: IT
authors.lastname: Kantariia
authors.forename: I I
authors.initials: II
authors.lastname: Megreladze
authors.forename: N N
authors.initials: NN
authors.lastname: Lapiashvili
authors.forename: M B
authors.initials: MB
authors.lastname: Kanashvili
mesh_terms: D000328:Adult; D020732:Cytogenetic Analysis; D004697:Endocarditis, Bacterial / Q000276:immunology* / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D007136:Immunoglobulins / Q000276:immunology*; D053685:Laser Therapy; D008214:Lymphocytes / Q000276:immunology*; D008297:Male
chemical_list: D007136:Immunoglobulins