title: Treatment of limited extent extramammary Paget's disease with 5 percent imiquimod cream.
abstract: Extramammary Paget's disease (EMPD) is a rare neoplastic condition of apocrine gland-bearing skin, which may be associated with internal malignancy. Although surgical excision is the generally accepted standard of care for EMPD, treatment with topical imiquimod 5 percent cream has reportedly been efficacious in clearing lesions. We report the case of a 78-year-old woman with biopsy-proven EMPD of the thigh treated successfully with imiquimod application thrice weekly for 16 weeks.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Christy
authors.initials: C
authors.lastname: Badgwell
authors.forename: Ted
authors.initials: T
authors.lastname: Rosen
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D000077271:Imiquimod; D010145:Paget Disease, Extramammary / Q000188:drug therapy* / Q000473:pathology*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D013848:Thigh; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod