title: [Progressive multifocal leukoencephalopathy secondary to JC virus infection after liver transplantation and treatment of recurrent hepatitis C].
abstract: Progressive multifocal leucoencephalopathy due to JC virus is a rare complication of liver transplantation. Only four cases have already been described in the literature. This disease is difficult to differentiate from leucoencephalopathy associated with immunosuppressive drugs such as cyclosporin or tacrolimus. Positive diagnosis of progressive multifocal leucoencephalopathy no longer requires cerebral biopsy. It must be confirmed by positive JC virus RNA amplification in the cerebrospinal fluid. We report a case of progressive multifocal leucoencephalopathy occurring 18 months after liver transplantation for hepatitis C-related cirrhosis.
authors.affiliation: Service d'Hépato-Gastroentérologie, Hôpital de la Conception, Marseille.
authors.forename: Sophie
authors.initials: S
authors.lastname: Alibert
authors.forename: René
authors.initials: R
authors.lastname: Gérolami
authors.forename: David
authors.initials: D
authors.lastname: Tammam
authors.forename: Patrick
authors.initials: P
authors.lastname: Borentain
authors.forename: Hervé
authors.initials: H
authors.lastname: Tissot-Dupont
authors.forename: Christine
authors.initials: C
authors.lastname: Zandotty
authors.forename: Jean
authors.initials: J
authors.lastname: Hardwigsen
authors.forename: Mona
authors.initials: M
authors.lastname: Stefaniescu
authors.forename: Carlos
authors.initials: C
authors.lastname: Barrantes
authors.forename: Yves-Patrice
authors.initials: YP
authors.lastname: Le Treut
authors.forename: Danièle
authors.initials: D
authors.lastname: Botta-Fridlund
mesh_terms: D005260:Female; D006526:Hepatitis C / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000209:etiology*; D008103:Liver Cirrhosis / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation; D008875:Middle Aged; D012008:Recurrence