Recurrent intracardiac thrombosis as an unusual manifestation of inherited thrombophilia.
Patients with inherited thrombophilia are at high risk for the development of venous thrombosis that manifests mainly as deep venous thrombosis of the legs and/or pulmonary embolism. We report spontaneous right-sided intracardiac thrombosis in a young man as an unusual manifestation of inherited thrombophilia. The diagnosis of thrombophilia was confirmed by demonstration of the prothrombin-G20210A-mutation in the homozygous state. A second spontaneous intracardiac thrombosis occurred 3 years after discontinuation of oral anticoagulant treatment. This indicates the high risk for recurrence in patients developing intracardiac thrombosis in the absence of an underlying cardiac disease and warrants long-term oral anticoagulant treatment.
Ohlenforst
Sandra
S
Mueller
Jens
J
Rox
Jutta M
JM
Oldenburg
Johannes
J
Pötzsch
Bernd
B
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003328:Coronary Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D012008:Recurrence; D012307:Risk Factors; D019851:Thrombophilia / Q000150:complications* / Q000235:genetics
D000925:Anticoagulants