Melanoma metastasis to the breast masquerading as fibroadenoma.
BACKGROUND
Although primary malignant breast lesions are common, tumor metastasis to the breast is rare. Melanoma metastasis to the breast occurs even more rarely.


METHODS
In the present case report, we describe an adolescent girl with malignant melanoma metastasis to the breast masquerading as fibroadenoma, in which it was impossible to perform differential diagnosis based only on the physical examination and ultrasonographic evaluation. The definitive diagnosis both of the primary and of the metastatic lesion was reached by immunohistochemistry, which revealed positivity to Mart-1 antibody.


CONCLUSIONS
Melanoma metastasizing to the breast is occasionally indistinguishable from a benign lesion at ultrasonographic evaluation. Emphasis should be made on the importance of a correct diagnosis prior to therapeutic management.
da Silva
Benedito Borges
BB
Department of Gynecology, Federal University of Piauí, Teresina, Piauí, Brazil. beneditoborges@globo.com
da Silva
Raimundo Gerônimo
RG
Lopes Costa
Pedro Vitor
PV
Pires
Cleicilene Gomes
CG
da Silva Pinheiro
Gevina
G
D000293:Adolescent; D001943:Breast Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008545:Melanoma / Q000175:diagnosis / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology*; D013848:Thigh; D014463:Ultrasonography