title: Higher serum triglyceride level in patients with acute ischemic stroke is associated with lower infarct volume on CT brain scans.
abstract: We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47-93 years) with anterior circulation (75%), posterior circulation (9%) or lacunar infarcts (16%) were examined. All patients were admitted within 24 h of the symptom onset, and CT scans were taken over the subsequent 24-72 h. With adjustment for the infarct type, age, sex, timing of CT imaging (24-36, >36-48 or >48-72 h since admission), atrial fibrillation, hypertension, fasting cholesterol and glucose levels, a higher (> or =1.70 mmol/l) fasting serum triglyceride level (within 24 h after admission) was associated with a lower infarct volume (p = 0.014). In line with a recent report on milder clinical symptoms in acute ischemic stroke patients with higher triglycerides, the results suggest an independent association between serum triglyceride level and stroke severity.
authors.affiliation: Department of Neurology, County Hospital VaraZdin, Croatia. pikija.slaven@vz.t-com.hr
authors.forename: Slaven
authors.initials: S
authors.lastname: Pikija
authors.forename: Drazen
authors.initials: D
authors.lastname: Milevcić
authors.forename: Vladimir
authors.initials: V
authors.lastname: Trkulja
authors.forename: Spomenka
authors.initials: S
authors.lastname: Kidemet-Piskac
authors.forename: Ivan
authors.initials: I
authors.lastname: Pavlicek
authors.forename: Nedeljko
authors.initials: N
authors.lastname: Sokol
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism; D020520:Brain Infarction / Q000097:blood* / Q000000981:diagnostic imaging*; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D020243:Infarction, Anterior Cerebral Artery / Q000097:blood* / Q000000981:diagnostic imaging*; D020762:Infarction, Posterior Cerebral Artery / Q000097:blood* / Q000000981:diagnostic imaging*; D008297:Male; D008432:Mathematical Computing; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D014280:Triglycerides / Q000097:blood*
chemical_list: D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol