Enzymatic biosensors.
The biosensor field has grown enormously since the first demonstration of the biosensor concept by Leland C. Clark, Jr. in 1962. Today's biosensor market is dominated by glucose biosensors, mass-produced enzyme electrodes for the rapid self-diagnosis of blood glucose levels by diabetes sufferers. Here we take a historical look at the inception, growth, and development of the enzyme biosensor field from a commercial viewpoint. The current status of the technology is evaluated and future trends in this dynamic and fast-moving field are also anticipated.
Newman
Jeffrey D
JD
Institute of BioScience and Technology, Cranfield University, Silsoe, Bedfordshire MK45 4DT, United Kingdom. j.d.newman@cranfield.ac.uk
Setford
Steven J
SJ
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation / Q000379:methods; D019295:Computational Biology / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D023281:Genomics / Q000295:instrumentation / Q000379:methods; D006801:Humans; D040901:Proteomics / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results
D004800:Enzymes, Immobilized