title: Bisoprolol improves echocardiographic parameters of left ventricular diastolic function in patients with systemic hypertension.
abstract: Left ventricular (LV) diastolic dysfunction (LVD) is a common complication secondary to hypertension. It has been reported that bisoprolol is effective in reducing blood pressure and has beneficial cardiac effects in patients with hypertension. However, its effect on LV diastolic function has not been studied in detail. In this study, we sought to determine bisoprolol's effect on left ventricle diastolic function. Data from 25 patients were statistically analyzed. Peaks E and A wave, E/A ratio, isovolumetric relaxation time and E wave deceleration time were measured echocardiographically. Doppler echocardiography measurements after bisoprolol treatment revealed an improvement in LV diastolic function. In conclusion, our results show that treatment with bisoprolol, improves echocardiographic parameters of LV diastolic function after 3 months of treatment.
authors.affiliation: Golcuk Army Hospital, Department of Cardiology, Golcuk, Kocaeli, Turkey. fikretilgenli@yahoo.com
authors.forename: T Fikret
authors.initials: TF
authors.lastname: Ilgenli
authors.forename: Fethi
authors.initials: F
authors.lastname: Kilicaslan
authors.forename: Ata
authors.initials: A
authors.lastname: Kirilmaz
authors.forename: Mehmet
authors.initials: M
authors.lastname: Uzun
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D017298:Bisoprolol / Q000627:therapeutic use*; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
chemical_list: D000959:Antihypertensive Agents; D017298:Bisoprolol