Spontaneous mesenteric hemorrhage associated with Ehlers-Danlos syndrome.
The vascular type of Ehlers-Danlos syndrome is a genetic disorder of connective tissue and is frequently associated with catastrophic arterial complications. Its surgical treatment is extremely difficult because of the fragility of vessels. This article describes three patients with vascular type of Ehlers-Danlos syndrome who developed mesenteric hemorrhage due to spontaneous arterial rupture. The clinical and molecular characteristics of the disease are briefly reviewed.
Hosaka
Akihiro
A
Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.
Miyata
Tetsuro
T
Shigematsu
Hiroshi
H
Deguchi
Jun-o
JO
Kimura
Hideo
H
Nagawa
Hirokazu
H
Sato
Osamu
O
Sakimoto
Takehiko
T
Mochizuki
Tomoyuki
T
D034841:Abdominal Cavity; D000328:Adult; D000783:Aneurysm / Q000209:etiology; D000784:Aortic Dissection / Q000209:etiology; D017544:Aortic Aneurysm, Abdominal / Q000209:etiology; D004535:Ehlers-Danlos Syndrome / Q000150:complications*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006406:Hematoma / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology*; D006499:Hepatic Artery / Q000473:pathology; D006801:Humans; D007083:Iliac Artery / Q000473:pathology; D007583:Jejunum / Q000098:blood supply; D008297:Male; D008638:Mesenteric Arteries / Q000473:pathology; D017537:Mesenteric Artery, Inferior / Q000473:pathology; D012077:Renal Artery / Q000473:pathology; D012422:Rupture, Spontaneous; D013157:Splenic Artery / Q000473:pathology