[A case of severe glaucoma with pseudopemphigoid successfully treated by filtration surgery using amniotic membrane].
BACKGROUND
It is necessary to decrease topical anti-glaucoma medication for severe glaucoma with pseudopemphigoid caused by anti-glaucoma eye drops. Glaucoma filtrating surgery is often needed instead of medication, but the prognosis is poor because it induces scar fomation and makes the filtrating bleb vanish.


METHODS
An 85-year-old male patient with exfoliation syndrome had twice undergone glaucoma surgery about ten years previously. His intra-ocular pressure (IOP) was high despite topical anti-glaucoma medication. At the first examination in our hospital, he had severe superficial punctate keratopathy, blephariticshortening and symblepharon, and we therefore diagnosed severe pseudopemphigoid induced by anti-glaucoma eye drops. Because his IOP could not be controlled by topical and general medication, we conducted a glaucoma filtrating operation using amniotic membrane.


CONCLUSIONS
The administration of oral anti-inflammatory drugs before and after surgery and the use of amniotic membrane prevented post-operative scar formation and the progress of symblepharon, resulting in the successful control of IOP after surgery.
Hino
Keiko
K
Department of Ophthalmology, Kyoto Prefectural University of Medicine Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-0841, Japan.
Mori
Kazuhiko
K
Sotozono
Chie
C
Ikeda
Yoko
Y
Naruse
Shigeta
S
Ishibashi
Takeshi
T
Nanjo
Yukako
Y
Kinoshita
Shigeru
S
D000369:Aged, 80 and over; D000650:Amnion; D002354:Carteolol / Q000009:adverse effects / Q000627:therapeutic use; D018463:Filtering Surgery; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D010391:Pemphigoid, Bullous / Q000139:chemically induced*; D010862:Pilocarpine / Q000009:adverse effects* / Q000627:therapeutic use; D011183:Postoperative Complications
D010862:Pilocarpine; D002354:Carteolol