title: Wide field multifocal and standard full field electroretinographic features of hemi retinal vein occlusion.
abstract: The purpose of this study was to document the standard full field electroretinographic (ERG) and wide field multifocal electroretinographic (WF-mfERG) findings in eyes with recent onset hemi-retinal vein occlusion (HRVO) and to compare the electro-diagnostic findings in the affected and fellow eyes with reference to normative data. Eight patients with HRVO were assessed using ERG and WF-mfERG. WF-mfERG first order responses from the affected hemi-retinae and the unaffected hemi-retinae in each affected eye were compared. WF-mfERG responses from each affected hemi-retina and from the symmetrical hemi-retina of each fellow eye were compared. ERG responses between affected and unaffected eyes were also compared. All electrodiagnostic tests were compared to normative data (5-95% confidence limits derived from age-related controls). WF-mfERG P1 and N1 implicit times were greater for the affected hemi-retinae than for the unaffected hemi-retinae (p <0.05). WF-mfERG N1 and P1 implicit times were prolonged (p < 0.05) and WF-mfERG P1/N1 amplitude ratios were significantly reduced (p < 0.05) for the affected eyes when compared with the fellow eyes. Maximal b-wave, cone b-wave and flicker implicit times were prolonged (p < 0.05) when comparing affected and fellow eyes. These results indicate that retinal injury due to HRVO culminates in significant delay of both ERG and WF-mfERG implicit times. These results suggest that WF-mfERG in combination with ERG may have a role in the management of HRVO.
authors.affiliation: Electrodiagnostic Department, Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, G12 0YN, UK.
authors.forename: Fiona Mary
authors.initials: FM
authors.lastname: Dolan
authors.forename: Stuart
authors.initials: S
authors.lastname: Parks
authors.forename: David
authors.initials: D
authors.lastname: Keating
authors.forename: Gordon Neale
authors.initials: GN
authors.lastname: Dutton
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D004596:Electroretinography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000503:physiopathology*; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000503:physiopathology*; D012720:Severity of Illness Index