title: Exercise training during hemodialysis improves dialysis efficacy and physical performance.
abstract: OBJECTIVE
  To determine the impact of a 20-week intradialytic exercise program, consisting of 60 minutes of cumulative duration, low-intensity exercise during the first 2 hours of dialysis, on dialysis efficacy, physical performance, and quality of life in self-care hemodialysis (HD) patients.
  
  
  METHODS
  One-group repeated measures.
  
  
  METHODS
  Satellite HD units affiliated with a Canadian teaching hospital.
  
  
  METHODS
  A convenience sample of 13 self-care HD patients who were stable on dialysis for a minimum of 6 months and were medically screened for significant cardiac, pulmonary, and/or musculoskeletal pathology that would preclude exercise.
  
  
  METHODS
  A 5-month intradialytic exercise program in which subjects exercised 3 times a week (cycle ergometer, mini-stepper) for 30 minutes in each of the first 2 hours of HD.
  
  
  METHODS
  Dialysis efficacy (in single-pool model of urea kinetics [spKt/V]) was assessed prior to and at the end of each month of the exercise program. Physical function (6-minute walk test [6MWT]), and quality of life. (Kidney Disease Quality of Life-Short Form [KDQOL]) were determined at baseline and at weeks 10 and 20 of the exercise program.
  
  
  RESULTS
  SpKt/V increased 11% at the end of the first month of the program (P<.05) and remained elevated for the duration of the program (18%-19%). Distance walked on the 6MWT increased by 14% at both weeks 10 and 20 (P<.05). No changes were noted in KDQOL scores.
  
  
  CONCLUSIONS
  A low-intensity intradialytic exercise program is a viable adjunctive therapy, which improves HD efficacy and physical function in HD patients.
authors.affiliation: School of Rehabilitation Therapy, Queen's University, and Division of Nephrology, Kingston General Hospital, ON, Canada.
authors.forename: Trisha L
authors.initials: TL
authors.lastname: Parsons
authors.forename: Edwin B
authors.initials: EB
authors.lastname: Toffelmire
authors.forename: Cheryl E
authors.initials: CE
authors.lastname: King-VanVlack
mesh_terms: D000328:Adult; D000368:Aged; D015444:Exercise; D017079:Exercise Tolerance / Q000502:physiology*; D006801:Humans; D007677:Kidney Function Tests; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000503:physiopathology / Q000628:therapy*; D012648:Self Care; D016896:Treatment Outcome