title: Autopsy findings in the nervous system and ovarian tumour of two patients with paraneoplastic cerebellar degeneration.
abstract: OBJECTIVE
  To review autopsy findings in paraneoplastic cerebellar degeneration.
  
  
  METHODS
  We report the autopsy results of two individuals with paraneoplastic cerebellar degeneration and ovarian cancer.
  
  
  RESULTS
  Both patients had extensive loss of cerebellar Purkinje cells and general activation of microglia in the central nervous system, as well as signs of immunactivation in the medulla.
  
  
  CONCLUSIONS
  The immunoactivation in PCD is widespread and involving more than the cerebellum.
authors.affiliation: Department of Clinical Medicine, University of Bergen, Bergen, Norway. anette.storstein@helse-bergen.no
authors.forename: A
authors.initials: A
authors.lastname: Storstein
authors.forename: B
authors.initials: B
authors.lastname: Krossnes
authors.forename: C A
authors.initials: CA
authors.lastname: Vedeler
mesh_terms: D000369:Aged, 80 and over; D001344:Autopsy; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D020362:Paraneoplastic Cerebellar Degeneration / Q000473:pathology*; D011689:Purkinje Cells / Q000502:physiology