[Are PUFAs n-3 really important in diet?].
If cardiovascular secondary prevention as well as COPD benefit from PUFAs supplementation, mainly in our societies where n-3 lack is close to n-6:n-3 misbalance, the usefulness of these supplements in many diseases (inflammatory or psychiatric for instance), is not yet established despite numerous randomised controlled studies and meta-analysis. The only counter indication to their prescription now is the presence of an implantable defibrillator. Their effect on prostate cancer remains doubtful. PUFAs n-3 marine sources should be free of pollution.
Laurent-Jaccard
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Service d'endocrinologie, diabétologie et métabolisme, Consultation d'obésité et des troubles du comportement alimentaire, CHUV-PMU, Lausanne. annchris@phoenix818.ch
D004032:Diet; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006801:Humans; D011315:Preventive Medicine
D015525:Fatty Acids, Omega-3