title: [An experimental study on alveolar ridge preservation prior to dental implant placement].
abstract: OBJECTIVE
  To evaluate the combination of surgical grade calcium sulfate hemihydrate (SGCS) and platelet-rich plasma (PRP) for alveolar ridge preservation prior to implant placement.
  
  
  METHODS
  Changes of bone quantity and quality in extraction sites following the SGCS/PRP and SGCS implantations were investigated by spiral computer tomography scan, bone scintigraphy, radiographic, histological and histomorphometric examinations.
  
  
  RESULTS
  The placement of SGCS/PRP reduced the resorption of the alveolar ridge. It also promoted bone metabolism and bone-to-implant contact. The addition of PRP to SGCS achieved the enhancement of the bone metabolism only at the early healing phase.
  
  
  CONCLUSIONS
  In this animal experiment, SGCS/PRP may be used as fresh extraction sockets graft for alveolar ridge preservation prior to implant placement.
authors.affiliation: Key Laboratory of Oral Biomedical Engineering of Ministry of Education, School of Stomatology, Wuhan University, Wuhan 430079, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Shi
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yi-ning
authors.initials: YN
authors.lastname: Wang
authors.forename: Xiang-rong
authors.initials: XR
authors.lastname: Cheng
mesh_terms: D016301:Alveolar Bone Loss / Q000517:prevention & control*; D000539:Alveolar Process / Q000473:pathology / Q000601:surgery*; D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D002133:Calcium Sulfate / Q000627:therapeutic use*; D015921:Dental Implants; D004285:Dogs; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D016348:Osseointegration / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology; D053657:Platelet-Rich Plasma; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D018786:Bone Substitutes; D015921:Dental Implants; D019275:Radiopharmaceuticals; D002133:Calcium Sulfate