Influence of selected tensides on the hydrocortisone concentration equilibrium balance in micelles and the dispersing center.
The degree of hydrocortisone binding, was investigated by means of equilibrium dialysis in the presence of 1% or 3% micellar solutions of polysorbate 20 and 80. Stabilization of the concentration equilibrium was found in all the cases investigated. The degree of hydrocortisone binding in micelles depends on the concentration and type of tenside used.
Szcześniak
M
M
Department of Pharmaceutical Technology, Wrocław Medical University, Wrocław, Poland.
Kubis
A A
AA
D004058:Diffusion; D006854:Hydrocortisone / Q000737:chemistry*; D008567:Membranes, Artificial; D008823:Micelles; D011136:Polysorbates; D013056:Spectrophotometry, Ultraviolet; D013501:Surface-Active Agents / Q000737:chemistry*
D008567:Membranes, Artificial; D008823:Micelles; D011136:Polysorbates; D013501:Surface-Active Agents; D006854:Hydrocortisone