title: Esophageal carcinosarcoma with intramural metastasis.
abstract: A case of esophageal carcinosarcoma is described herein. A 58-year-old man presented with dysphagia and was admitted to our hospital. Imaging studies revealed a type 3 tumor in the upper intrathoracic esophagus with direct invasion to the left main bronchus. Analysis of a biopsy specimen revealed carcinosarcoma. The patient underwent esophageal bypass and chemoradiotherapy. Eight months after surgery, he died of esophago-bronchial fistula. Autopsy examination revealed liver metastasis, peritoneal dissemination and intramural metastasis. The sarcomatous component was predominant in the intramural and liver metastatic lesions.
authors.affiliation: Department of Surgical Oncology, Research Institution for Radiation Biology and Medicine, Hiroshima, Japan. ysanadasurg@hotmail.com
authors.forename: Y
authors.initials: Y
authors.lastname: Sanada
authors.forename: J
authors.initials: J
authors.lastname: Hihara
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaguchi
mesh_terms: D001706:Biopsy; D002296:Carcinosarcoma / Q000556:secondary* / Q000628:therapy; D003680:Deglutition Disorders / Q000209:etiology; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000628:therapy; D004947:Esophagus / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000556:secondary; D013274:Stomach Neoplasms / Q000556:secondary*; D014057:Tomography, X-Ray Computed