Sarcomatoid chromophobe renal cell carcinoma. A case report and review of the literature.
OBJECTIVE
We report herein the clinical, histological, and immunohistochemical features of a case of sarcomatoid chromophobe renal cell carcinoma.


RESULTS
A 59-year-old woman referred a two-month history of constant right flank pain, and hematuria. A right radical nephrectomy was performed. Gross pathologic examination showed a tumor located in the lower part of the kidney with two different aspects. Histologically, the tumor was composed of two intermixed distinct morphologic components: a chromophobe renal cell carcinoma and a high-grade spindle cell sarcoma.


CONCLUSIONS
Our case represent a typical sarcomatoid chromophobe cell carcinoma. This unusual renal cancer has the potential to behave aggressively and to metastasize.
Parada
David
D
Service of Pathology, Vargas Hospital, José María Vargas School of Medicine, Central University of Venezuela, Caracas. parada@cantv.net
Peña
Karla
K
Moreira
Otto
O
D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged