title: MR imaging and prognosis of hypoxic-ischemic leukoencephalopathy.
abstract: OBJECTIVE
  To correlate prognosis of hypoxic-ischemic white-matter injury with magnetic resonance imaging (MRI).
  
  
  METHODS
  In a retrospective review at an urban medical center, three adult and three pediatric patients with predominant white-matter involvement caused by hypoxic- ischemic injury were evaluated over a 15-month period.
  
  
  RESULTS
  Five patients with MRI-defined hypoxic-ischemic leukoencephalopathy had a favorable outcome, and one with associated diffusion-weighted abnormality of deep gray structures died.
  
  
  CONCLUSIONS
  The prognosis of hypoxic-ischemic leukoencephalopathy is more favorable than previously reported, and diffusion-weighted imaging abnormality of deep gray structures was associated with a poor outcome.
authors.affiliation: Department of Neurology, Hartford Hospital, CT 06102-5037, USA. Pfinell@harthosp.org
authors.forename: Pasquale F
authors.initials: PF
authors.lastname: Finelli
authors.forename: Francis J
authors.initials: FJ
authors.lastname: DiMario
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015140:Dementia, Vascular / Q000150:complications* / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000473:pathology*; D008297:Male; D011379:Prognosis