title: Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome.
abstract: OBJECTIVE
  To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) and polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Case report.
  
  
  METHODS
  University department of obstetrics and gynecology, Italy.
  
  
  METHODS
  A woman complaining of RM who had PCOS and insulin resistance.
  
  
  METHODS
  Clinical, biochemical, and instrumental assessments.
  
  
  METHODS
  Administration of metformin hydrochloride before and throughout pregnancy.
  
  
  RESULTS
  After 3 months of treatment, the patient became pregnant. The pregnancy had a physiologic development, and at 39 weeks of gestation, the patient spontaneously delivered a healthy infant.
  
  
  CONCLUSIONS
  Metformin has shown to be effective in an insulin-resistant PCOS woman with RM.
authors.affiliation: Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Italy. stefanopalomba@tin.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Palomba
authors.forename: Angela
authors.initials: A
authors.lastname: Falbo
authors.forename: Francesco
authors.initials: F
authors.lastname: Orio
authors.forename: Tiziana
authors.initials: T
authors.lastname: Russo
authors.forename: Achille
authors.initials: A
authors.lastname: Tolino
authors.forename: Fulvio
authors.initials: F
authors.lastname: Zullo
mesh_terms: D000026:Abortion, Habitual / Q000517:prevention & control*; D000328:Adult; D016640:Diabetes, Gestational / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D008687:Metformin / Q000008:administration & dosage*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy*; D011247:Pregnancy; D016896:Treatment Outcome
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin