title: Epilepsia partialis continua in a patient with Behçet's disease.
abstract: Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder of unknown aetiology. Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate.
authors.affiliation: Department of Neurology, Akdeniz University School of Medicine, 07070 Antalya, Turkey. berrina@akdeniz.edu.tr
authors.forename: Berrin
authors.initials: B
authors.lastname: Aktekin
authors.forename: Ebru Apaydin
authors.initials: EA
authors.lastname: Doğan
authors.forename: Yurttaş
authors.initials: Y
authors.lastname: Oğuz
authors.forename: Kamil
authors.initials: K
authors.lastname: Karaali
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D010507:Periodicity; D012008:Recurrence
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone