Increased thalamostriatal-mesiotemporal glucose uptake with symptom remission in schizophrenia--a case report.
Electroconvulsive therapy (ECT) is an effective modality of treatment, especially in medication-resistant psychiatric conditions. We report the case of an individual with schizophrenia and prominent negative symptoms who, despite poor response to medications, exhibited significant symptom remission with ECT. Post-ECT fluoro-2-deoxy-D-glucose positron emission tomography scan revealed increased uptake in the thalamostriatal-mesiotemporal regions, suggesting a possible mechanism of action of ect in alleviation of negative symptoms.
Seethalakshmi
R
R
Department of Psychiatry, King Edward Memorial Hospital, Mumbai, Maharashtra, India.
Parkar
S R
SR
Nair
N
N
Pandit
A G
AG
D000328:Adult; D004565:Electroconvulsive Therapy; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography; D012559:Schizophrenia / Q000000981:diagnostic imaging / Q000628:therapy*; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000378:metabolism*; D013788:Thalamus / Q000000981:diagnostic imaging / Q000378:metabolism*; D014793:Visual Cortex / Q000000981:diagnostic imaging / Q000378:metabolism*
D019788:Fluorodeoxyglucose F18; D005947:Glucose