title: Analgesic activity of some Indian medicinal plants.
abstract: In the present study of some of the Indian medicinal plants Sida acuta whole plant (Malvaeae), Stylosanthes fruticosa (whole plant) (Papilionaceae), Toona ciliata (heart wood) (Meliaceao), Bougainvilla spectabilis (leaves) (Nyctaginaceae), Ficus glomerata (bark, leaves) (Moraceae) and Polyalthia longifolia (leaves) (Annonaceae). The different plants were used in folklore medicine in the treatment of toothache and strengthening of gums, anthelmintic, kidney diseases, analgesic, anti-inflammatory, hepatoprotective, antihyperglycaemic, antihyperglycaemic and anticancer. The extract was prepared using powdered material with ethanol, concentrated under vacuo and were evaluated for analgesic activity by analgesiometer at three dose level (100, 300 and 500mg/kg). Analgesic activity was significant with Toona ciliata (heart wood) ethanolic extract when compared with other extracts and its activity was confirmed by tail immersion method.
authors.affiliation: S.R.M. College of Pharmacy, Kattankulathur 603203, Kancheepuram (District), Tamilnadu, India. pmalairajan@yahoo.co.in
authors.forename: P
authors.initials: P
authors.lastname: Malairajan
authors.lastname: Geetha Gopalakrishnan
authors.forename: S
authors.initials: S
authors.lastname: Narasimhan
authors.forename: K
authors.initials: K
authors.lastname: Jessi Kala Veni
mesh_terms: D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D006358:Hot Temperature; D007194:India; D007274:Injections, Intraperitoneal; D008297:Male; D008519:Medicine, Traditional; D051379:Mice; D010146:Pain / Q000517:prevention & control*; D010147:Pain Measurement / Q000187:drug effects; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D014934:Wood
chemical_list: D000700:Analgesics; D010936:Plant Extracts