title: [Drug interactions of tacrolimus].
abstract: Allogeneic hematopoetic stem cell transplantations can be complicated by a graft-versus-host disease (GvHD), i.e., immunocompetent cells from the transplanted bone marrow act against solid organs of the recipient. A GvHD is treated with immunosuppressants. Consequently, further drugs are required, for example in order to prevent infections and result in in polymedication of those patients with a risk of drug interactions. In this case report, drug interactions between tacrolimus and concomitant therapy in a stem-cell-transplanted patient are discussed.
authors.affiliation: Klinische Pharmazie und Pharmakotherapie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: Melanie E
authors.initials: ME
authors.lastname: Sumner
authors.forename: Stefanie
authors.initials: S
authors.lastname: Albers
authors.forename: Klaus G
authors.initials: KG
authors.lastname: Schmidt
authors.forename: Hans Jürgen
authors.initials: HJ
authors.lastname: Laws
authors.forename: Stephanie
authors.initials: S
authors.lastname: Läer
mesh_terms: D004347:Drug Interactions; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D033581:Stem Cell Transplantation; D016559:Tacrolimus / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus