Recurrent aseptic encephalitis in periodic fever, aphthous stomatitis, pharyngitis and adenopathy (PFAPA) syndrome.
An 11-year-old boy with episodes of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) is reported. Two PFAPA episodes were associated with aseptic encephalitis and seizures. Recurrent acute aseptic encephalitis or seizures have never been reported during the febrile episodes of PFAPA. This possible association is discussed within the context of the etiology of PFAPA.
Frye
Richard E
RE
Department of Pediatrics, University of Florida, Gainesville 32610-0296, USA. fryerich@peds.ufl.edu
D002648:Child; D004660:Encephalitis / Q000209:etiology*; D005334:Fever / Q000150:complications*; D006801:Humans; D008199:Lymphadenitis / Q000150:complications*; D008297:Male; D010507:Periodicity; D010612:Pharyngitis / Q000150:complications*; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000150:complications*; D013577:Syndrome