title: Promoter mutations of an essential gene for pollen development result in disease resistance in rice.
abstract: Disease resistance and sexual reproductive development are generally considered as separate biological processes, regulated by different sets of genes. Here we show that xa13, a recessive allele conferring disease resistance against bacterial blight, one of the most devastating rice diseases worldwide, plays a key role in both disease resistance and pollen development. The dominant allele, Xa13, is required for both bacterial growth and pollen development. Promoter mutations in Xa13 cause down-regulation of expression during host-pathogen interaction, resulting in the fully recessive xa13 that confers race-specific resistance. The recessive xa13 allele represents a new type of plant disease resistance.
authors.affiliation: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Chu
authors.forename: Meng
authors.initials: M
authors.lastname: Yuan
authors.forename: Jialing
authors.initials: J
authors.lastname: Yao
authors.forename: Xiaojia
authors.initials: X
authors.lastname: Ge
authors.forename: Bin
authors.initials: B
authors.lastname: Yuan
authors.forename: Caiguo
authors.initials: C
authors.lastname: Xu
authors.forename: Xianghua
authors.initials: X
authors.lastname: Li
authors.forename: Binying
authors.initials: B
authors.lastname: Fu
authors.forename: Zhikang
authors.initials: Z
authors.lastname: Li
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Bennetzen
authors.forename: Qifa
authors.initials: Q
authors.lastname: Zhang
authors.forename: Shiping
authors.initials: S
authors.lastname: Wang
mesh_terms: D000483:Alleles; D005799:Genes, Dominant / Q000502:physiology; D020043:Genes, Essential / Q000502:physiology*; D005808:Genes, Recessive / Q000502:physiology; D009154:Mutation; D012275:Oryza / Q000235:genetics / Q000254:growth & development / Q000382:microbiology*; D010935:Plant Diseases / Q000235:genetics* / Q000382:microbiology; D030821:Plants, Genetically Modified; D011058:Pollen / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*; D011401:Promoter Regions, Genetic / Q000235:genetics