Three-dimensional X-ray coronary angiography in the porcine model: A feasibility study.
OBJECTIVE
Three-dimensional high-spatial-resolution angiograms of the coronary arteries were acquired with an electrocardiogram-gated three-dimensional rotational angiography technique on an interventional X-ray system.


METHODS
During selective injection of contrast material in the left and right coronary artery, projection images were obtained in eight pigs during a continuous rotation of the X-ray gantry over an angular range of 180 degrees within 8 seconds.


RESULTS
Three-dimensional tomographic reconstruction depicted the proximal, medial, and distal sections of the main arteries as well as the main bifurcations in multiple cardiac phases in all animals.


CONCLUSIONS
For the first time, this feasibility study shows that a three-dimensional angiogram of the coronary arteries can be obtained intraprocedurally in a conventional interventional suite by means of tomographic reconstruction from projection images.
Rasche
Volker
V
Department Technical Systems, Philips Research Laboratories, Röntgenstr. 24-26, D-22315 Hamburg, Germany. Volker.Rasche@uniklinik-ulm.de
Movassaghi
Babak
B
Grass
Michael
M
Schäfer
Dirk
D
Kühl
Harald P
HP
Günther
Rolf W
RW
Bücker
Arno
A
D000465:Algorithms; D000818:Animals; D001185:Artificial Intelligence; D017023:Coronary Angiography / Q000379:methods*; D005240:Feasibility Studies; D021621:Imaging, Three-Dimensional / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine