Linear lichen planus and hepatitis C.
A 23-year-old man with hepatitis C was observed with brownish dome-shaped papules in a linear pattern on the chest. The papules were determined clinically and pathologically to be linear lichen planus. These lesions appeared during an interferon-alpha therapy for his hepatitis and resolved after topical treatment with tacrolimus ointment. Linear lichen planus and hepatitis C have been reported only twice previously. The association between these disorders and the potential role of interferon therapy are discussed.
Domínguez
María Victoria Guiote
MV
Department of Dermatology, San Cecilio Hospital, Granada, Spain. viviguiote@yahoo.es
Mateu
Anna Vilanova
AV
Vieira
Ricardo
R
Solano
Juan Linares
JL
Sintes
Ramón Naranjo
RN
Salmerón
María Teresa Gutiérrez
MT
D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D006526:Hepatitis C / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016898:Interferon-alpha / Q000009:adverse effects*; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D016559:Tacrolimus / Q000627:therapeutic use
D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D016898:Interferon-alpha; D016559:Tacrolimus