Oral hypertonic glucose solution in the treatment of infantile colic.
BACKGROUND
Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC.


METHODS
A total of 25 infants diagnosed as typical IC were given 1 mL of 30% glucose solution or sterile water for 4 days consecutively, in a randomized, double blind crossover trial. The effect was measured by parents' scoring.


RESULTS
Parents reported varying degrees of improvement in 16 infants (64%) given glucose solution, and in 12 infants (48%) given placebo. Comparison of treatment modalities were statistically significant (P = 0.031). There was no side-effect during treatments.


CONCLUSIONS
The present study revealed that 30% glucose was effective in the treatment of IC. Since oral glucose solution is natural, safe, cheap and easily achievable, it might be considered as an alternative therapy.
Akçam
Mustafa
M
Department of Pediatrics, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey.
Yilmaz
Aygen
A
D003085:Colic / Q000188:drug therapy*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D005950:Glucose Solution, Hypertonic / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male
D005950:Glucose Solution, Hypertonic