title: Avellino corneal dystrophy exacerbated after LASIK: scanning electron microscopic findings.
abstract: OBJECTIVE
  To evaluate the ultrastructure of the cornea of Avellino corneal dystrophy (ACD) exacerbated by LASIK.
  
  
  METHODS
  Three ACD patients with exacerbation of granular corneal deposits after LASIK underwent surgical removal of the corneal flap. The corneal flap was processed for scanning electron microscopy (SEM).
  
  
  RESULTS
  SEM of all patients showed abnormal granular clusters in the fibrils of the corneal flap.
  
  
  CONCLUSIONS
  Laser in situ keratomileusis induces corneal collagen abnormalities and adhesions of granular material in ACD patients.
authors.affiliation: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seodaemun-ku, Seoul, Korea.
authors.forename: Mi In
authors.initials: MI
authors.lastname: Roh
authors.forename: Hans E
authors.initials: HE
authors.lastname: Grossniklaus
authors.forename: So-Hyang
authors.initials: SH
authors.lastname: Chung
authors.forename: Shin Jeong
authors.initials: SJ
authors.lastname: Kang
authors.forename: Woon Cho
authors.initials: WC
authors.lastname: Kim
authors.forename: Eung Kweon
authors.initials: EK
authors.lastname: Kim
mesh_terms: D000328:Adult; D003317:Corneal Dystrophies, Hereditary / Q000209:etiology* / Q000648:ultrastructure*; D003319:Corneal Stroma / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D013524:Surgical Flaps / Q000473:pathology*