title: [Complications of heparin administration].
abstract: Heparin as an indirect anticoagulant is used in the clinical practice for more than 60 years. It is an effective drug, but it has limitations. To the side effects belong the heparin resistance, risk of bleeding (haemorrhage), hypersensitivity reactions and heparin-induced osteoporosis. The low-molecular-weight heparins exhibit fewer side effects, but it is still necessary to know about them.
authors.affiliation: Oddĕlení klinické hematologie FN Brno. mmatys@fnbrno.cz
authors.forename: M
authors.initials: M
authors.lastname: Matýsková
authors.forename: A
authors.initials: A
authors.lastname: Buliková
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology; D062787:Drug Overdose; D004351:Drug Resistance; D006470:Hemorrhage / Q000139:chemically induced; D006493:Heparin / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D006493:Heparin