Elevated serum surfactant protein A and D in pulmonary alveolar microlithiasis.
Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by widespread localization of calcispherites in the alveolar spaces. The authors report two cases of PAM, with markedly elevated sera concentrations of surfactant protein-A and surfactant protein-D, which showed a tendency to increase as the disease progressed. Therefore, surfactant protein-A and surfactant protein-D may function as serum markers to monitor the disease activity and progression of PAM.
Takahashi
Hiroki
H
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Chiba
Hirofumi
H
Shiratori
Masanori
M
Tachibana
Teruo
T
Abe
Shosaku
S
D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D020347:Lithiasis / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology; D008171:Lung Diseases / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011650:Pulmonary Alveoli; D037662:Pulmonary Surfactant-Associated Protein A / Q000097:blood*; D037663:Pulmonary Surfactant-Associated Protein D / Q000097:blood*; D014057:Tomography, X-Ray Computed
D015415:Biomarkers; D037662:Pulmonary Surfactant-Associated Protein A; D037663:Pulmonary Surfactant-Associated Protein D