Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus.
A previously healthy 16-year-old boy developed papular purpuric gloves and socks syndrome concomitant with mononeuritis multiplex attributable to acute infection with parvovirus B19. A cutaneous biopsy showed lymphocytic lichenoid vasculitis and perineuritis. We discuss the relevance of these pathologic findings, and we suggest a correlation with the patient's neurologic condition. This case illustrates the difficulties in differentiating dysesthesia accompanying cutaneous manifestations of exanthem from neurologic disease on the basis of the clinical appearance alone.
Aguilar-Bernier
Miguel
M
Department of Dermatology, University of Valladolid, Hospital Clínico Universitario, Valladolid, Spain. miagber@aedv.es
Bassas-Vila
Julio
J
Torné-Gutiérrez
José Ignacio
JI
Martínez-García
Gerardo
G
Aragoneses-Fraile
Henar
H
Miranda-Romero
Alberto
A
D000293:Adolescent; D016731:Erythema Infectiosum / Q000150:complications* / Q000473:pathology*; D005528:Foot / Q000473:pathology; D006225:Hand / Q000473:pathology; D006801:Humans; D008297:Male; D020422:Mononeuropathies / Q000150:complications* / Q000473:pathology*; D016732:Parvovirus B19, Human / Q000472:pathogenicity*; D013577:Syndrome