Minimising ventilator induced lung injury in preterm infants.
Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the "new BPD" may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.
Donn
S M
SM
Division of Neonatal-Perinatal Medicine, C S Mott Children's Hospital, 1500 E Medical Center Drive, Ann Arbor, MI, USA 48109-0254. smdonnmd@med.umich.edu
Sinha
S K
SK
D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology* / Q000517:prevention & control; D008171:Lung Diseases / Q000209:etiology* / Q000517:prevention & control; D008991:Monitoring, Physiologic; D012121:Respiration, Artificial / Q000009:adverse effects* / Q000379:methods