title: Keratoacanthoma centrifugum marginatum: response to topical 5-fluorouracil.
abstract: Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma, characterized by progressive peripheral growth with concomitant healing of the central area of the tumor. We present a patient with KCM who was treated with topical 5% 5-fluorouracil. This is the third reported case of KCM treated with this agent.
authors.affiliation: Department of Dermatology, Instituto Lauro de Souza Lima, São Paulo, Brazil. sayuriyuge@zipmail.com.br
authors.forename: Sayuri
authors.initials: S
authors.lastname: Yuge
authors.forename: Deise Aparecida Santos
authors.initials: DA
authors.lastname: Godoy
authors.forename: Maria Carolina Coelho de
authors.initials: MC
authors.lastname: Melo
authors.forename: Danilo Silveira
authors.initials: DS
authors.lastname: Sousa
authors.forename: Cleverson Teixeira
authors.initials: CT
authors.lastname: Soares
mesh_terms: D000369:Aged, 80 and over; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D007636:Keratoacanthoma / Q000188:drug therapy* / Q000473:pathology*; D007866:Leg; D008727:Methotrexate / Q000627:therapeutic use; D019233:Retreatment; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology*; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D005472:Fluorouracil; D008727:Methotrexate