Dissection of conformationally restricted inhibitors binding to a beta-glucosidase.
Gloster
Tracey M
TM
Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, YO10 5YW, UK.
Madsen
Robert
R
Davies
Gideon J
GJ
D001665:Binding Sites; D002236:Carbohydrate Conformation; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008958:Models, Molecular; D008968:Molecular Conformation; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship; D001617:beta-Glucosidase / Q000037:antagonists & inhibitors* / Q000737:chemistry
D004791:Enzyme Inhibitors; D001617:beta-Glucosidase