title: [Radical parametrectomy in women with invasive cervix cancer after previous simple hysterectomy].
abstract: OBJECTIVE
  Evaluate technique, indications and limits of surgical procedure in the treatment of cervical cancer diagnosed from uterus specimen from simple hysterectomy.
  
  
  METHODS
  Retrospective observational study, review of literature.
  
  
  METHODS
  Department of Obstetrics and Gynecology, 1st Medical Faculty and General Faculty Hospital, Charles University, Prague, Czech Republic.
  
  
  METHODS
  Women following radical parametrectomy with upper vaginectomy and pelvic lymphadenectomy were enrolled to the study. In all patients unexpected invasive cervical cancer was found from the uterus specimen after simple hysterectomy.
  
  
  RESULTS
  Together 10 patients were enrolled to the study. CIN was the indication for primary hysterectomy in all but two patients. There were two operative complications, cystostomy in both cases, treated properly during surgery. In the specimen from radical procedure residual tumor in parametria was found in 2 cases, and metastasis to pelvic nodes in 4 cases. There was no postoperative complication. Adjuvant radiotherapy was recommended in 4 patients due to positive lymph nodes, in one case due to residual tumor in parametria, and in one case for both reasons.
  
  
  CONCLUSIONS
  Radical parametrectomy with upper vaginectomy and pelvic lymphadenectomy should be considered as an alternative solution in patients following simple hysterectomy with unexpected finding of invasive cervical cancer. Morbidity of the procedure is higher in comparison to standard radical hysterectomy, however majority of complications are easy to repair. The most significant criteria for patient's selection for surgical approach is a depth of invasion to cervical stroma. In our group radical procedure obviated the need for radiotherapy in half of the patients.
authors.affiliation: Gynekologicko-porodnická klinika, 1. LF UK a VFN, Praha.
authors.forename: D
authors.initials: D
authors.lastname: Cibula
authors.forename: P
authors.initials: P
authors.lastname: Freitag
authors.forename: P
authors.initials: P
authors.lastname: Mares
authors.forename: J
authors.initials: J
authors.lastname: Svárovský
authors.forename: M
authors.initials: M
authors.lastname: Janousek
authors.forename: D
authors.initials: D
authors.lastname: Fischerová
authors.forename: J
authors.initials: J
authors.lastname: Sláma
authors.forename: M
authors.initials: M
authors.lastname: Strunová
authors.forename: M
authors.initials: M
authors.lastname: Zikán
authors.forename: N
authors.initials: N
authors.lastname: Jancárková
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007813:Laparotomy; D008197:Lymph Node Excision; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012086:Reoperation; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*