title: [Significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C].
abstract: BACKGROUND
  To investigate the significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C.
  
  
  METHODS
  Totally 56,400 anti-HCV negative blood samples collected from Jan. 2000 to Dec. 2003 were tested for HCV RNA by RT-PCR, and the patients who received the HCV RNA negative blood were followed up.
  
  
  RESULTS
  The HCV RNA positive rate was 2.5 per thousand (146/56,000) and none of the patients followed up suffered from HCV infection.
  
  
  CONCLUSIONS
  HCV RNA screening for the anti-HCV negative blood samples is very effective and feasible for prevention of post-transfusion hepatitis C.
authors.affiliation: Department of Infectious Diseases, Heilongjiang Provincial Hospital, Harbin 150036, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Yu-feng
authors.initials: YF
authors.lastname: Liu
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Zhao
authors.forename: Geng-shan
authors.initials: GS
authors.lastname: Tian
mesh_terms: D005240:Feasibility Studies; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008403:Mass Screening / Q000379:methods; D012367:RNA, Viral / Q000097:blood* / Q000235:genetics; D015203:Reproducibility of Results; D020133:Reverse Transcriptase Polymerase Chain Reaction; D065227:Transfusion Reaction
chemical_list: D012367:RNA, Viral