title: Effect of glycodelin on the production of vascular endothelial growth factor in cumulus cells.
abstract: Glycodelin modulates vascular endothelial growth factor (VEGF) production in cumulus cells in vitro. Patients with normal gonadotropin responses who were undergoing IVF demonstrated increased VEGF production to glycodelin, whereas poor responders had a decreased response to glycodelin.
authors.affiliation: Center for Reproductive Medicine and Fertility, Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia, USA.
authors.forename: Ellen C
authors.initials: EC
authors.lastname: Hayes
authors.forename: Celia E
authors.initials: CE
authors.lastname: Dominguez
authors.forename: Steven
authors.initials: S
authors.lastname: Voelkel
authors.forename: Mingqing
authors.initials: M
authors.lastname: Song
authors.forename: Aida S
authors.initials: AS
authors.lastname: Shanti
authors.forename: Ana A
authors.initials: AA
authors.lastname: Murphy
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005260:Female; D000071816:Glycodelin; D006023:Glycoproteins / Q000008:administration & dosage*; D006801:Humans; D009865:Oocytes / Q000187:drug effects* / Q000378:metabolism*; D011257:Pregnancy Proteins / Q000008:administration & dosage*; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*
chemical_list: D000071816:Glycodelin; D006023:Glycoproteins; C045246:PAEP protein, human; D011257:Pregnancy Proteins; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A