Observations on the exoerythrocytic stages of different isolates of Plasmodium cynomolgi in hepatocytes of New World aotus and Saimiri monkeys.
Sporozoites of 3 isolates of Plasmodium cynomolgi dissected from the salivary glands of Anopheles dirus and Anopheles quadrimaculatus were injected intravenously into 9 New World monkeys. Liver stage parasites were demonstrated in all 9 animals; 7 of these animals also produced blood stages after prepatent periods of 9 to 23 days.
Sullivan
JoAnn S
JS
Division of Parasitic Diseases and Scientific Resources Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Stewart
Ann
A
Bounngaseng
Amy
A
Sullivan
James J
JJ
Nace
Douglas
D
Williams
Allison
A
Galland
G Gale
GG
Williams
Tyrone
T
Henry
Fleetwood
F
Collins
William E
WE
D000818:Animals; D000852:Anopheles / Q000469:parasitology; D016645:Aotidae / Q000469:parasitology*; D004912:Erythrocytes / Q000469:parasitology; D022781:Hepatocytes / Q000469:parasitology*; D007275:Injections, Intravenous / Q000662:veterinary; D008253:Macaca mulatta; D008288:Malaria / Q000469:parasitology / Q000473:pathology / Q000635:transmission / Q000662:veterinary*; D016789:Plasmodium cynomolgi / Q000302:isolation & purification / Q000472:pathogenicity* / Q000502:physiology; D012453:Saimiri / Q000469:parasitology*; D034101:Sporozoites / Q000472:pathogenicity; D013997:Time Factors