title: Measles immunity and immunisation status in Australian children 1 to 4 years of age.
abstract: OBJECTIVE
  Determine measles seropositivity and vaccine coverage in children aged 1 to 4 years inclusive. Compare data in those who produced immunisation records and those who relied on parental recall. Establish variables associated with seropositivity.
  
  
  METHODS
  
  
  
  METHODS
  Population- and area-based, cluster sample of 1- to 4-year-olds; households surveyed by trained interviewer.
  
  
  METHODS
  Australia-wide, excluding New South Wales. Questionnaires completed between February and April 1995.
  
  
  METHODS
  2117 completed questionnaires were returned for children aged 1 to 4 years, 923 of whom provided a sufficient blood sample for analysis.
  
  
  RESULTS
  Overall seropositivity was 86% for the 923 children tested and was strongly associated with previous immunisation (P < 0.001) and age (P < 0.001), but not with parental report of a previous measles diagnosis (P = 0.581). Eight hundred and forty-three (91%) reported previous measles immunisation, with 760 (90%) of these testing seropositive. Four hundred and ninety-one (55%) parents/guardians produced immunisation records, while 400 (45%) relied on recall. Immunised children whose parents relied on recall were equally likely to be seropositive as children whose parents produced records. The 923 children tested were representative of the 2117 who completed questionnaires in all factors except age, where children below 2 years old were under represented (P < 0.001).
  
  
  CONCLUSIONS
  These data support the current second routine measles immunisation prior to school entry, and reinforce the need to promote the first routine dose to achieve measles elimination.
authors.affiliation: Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne, Australia. g.hogg@mdu.unimelb.edu.au
authors.forename: Geoffry G
authors.initials: GG
authors.lastname: Hogg
authors.forename: Raelene J
authors.initials: RJ
authors.lastname: Darlington
authors.forename: Katharine G
authors.initials: KG
authors.lastname: Hogg
authors.forename: Rosemary
authors.initials: R
authors.lastname: Lester
mesh_terms: D017677:Age Distribution; D000914:Antibodies, Viral / Q000097:blood*; D001315:Australia / Q000453:epidemiology; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006306:Health Surveys; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data*; D007223:Infant; D016015:Logistic Models; D008297:Male; D008457:Measles / Q000517:prevention & control*; D008458:Measles Vaccine / Q000008:administration & dosage*; D008459:Measles virus / Q000276:immunology*; D011159:Population Surveillance / Q000379:methods; D016036:Seroepidemiologic Studies; D012698:Serologic Tests; D011795:Surveys and Questionnaires
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine