title: Antimicrobial potentiality of Phyllanthus amarus against drug resistant pathogens.
abstract: The antimicrobial potentiality of the methanolic extract of Phyllanthus amarus (Family: Euphorbiaceae) was studied against some drug resistant pathogenic bacterial strains by disc diffusion and agar dilution method. The extract showed significant concentration-dependent antibacterial activity particularly against gram-negative microbes. The study illustrated the claim of the usefulness of the plant in dysenteric and diarrheal infections and also suggested its use in fever. The antibacterial action was mainly due to the isolated phyllanthin.
authors.affiliation: Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi - 835 215, India. avijitmazum@yahoo.com
authors.forename: Avijit
authors.initials: A
authors.lastname: Mazumder
authors.forename: Arun
authors.initials: A
authors.lastname: Mahato
authors.forename: Rupa
authors.initials: R
authors.lastname: Mazumder
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D024881:Drug Resistance, Bacterial; D029803:Phyllanthus / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts