title: Galbraith Award: simvastatin attenuates experimental cerebral vasospasm and ameliorates serum markers of neuronal and endothelial injury in patients after subarachnoid hemorrhage: a dose-response effect dependent on endothelial nitric oxide synthase.
authors.affiliation: Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: McGirt
authors.forename: Graeme F
authors.initials: GF
authors.lastname: Woodworth
authors.forename: Gustavo
authors.initials: G
authors.lastname: Pradilla
authors.forename: Federico
authors.initials: F
authors.lastname: Legnani
authors.forename: David
authors.initials: D
authors.lastname: Warner
authors.forename: Rafael
authors.initials: R
authors.lastname: Tamargo
authors.forename: Richard
authors.initials: R
authors.lastname: Clatterbuck
authors.forename: John R
authors.initials: JR
authors.lastname: Lynch
authors.forename: Daniel T
authors.initials: DT
authors.lastname: Laskowitz
mesh_terms: D000818:Animals; D001363:Awards and Prizes; D001488:Basilar Artery / Q000033:anatomy & histology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D009474:Neurons / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D011817:Rabbits; D019821:Simvastatin / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D013345:Subarachnoid Hemorrhage / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology; D020301:Vasospasm, Intracranial / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology
chemical_list: D019821:Simvastatin; D019001:Nitric Oxide Synthase