title: [Simultaneous liver-pancreas-duodenum transplantation: one case report and review of the literature].
abstract: OBJECTIVE
  To investigate the effect of treatment on end-stage liver disease and type-I diabetes mellitus with simultaneous liver-pancreas-duodenum transplantation.
  
  
  METHODS
  In September 2003, one patient with chronic hepatitis B, liver cirrhosis, hepatic cellular cancer, and insulin-dependent diabetes received simultaneous orthotopic liver and heterotopic pancreas-duodenum transplantation. Liver and pancreas graft function was monitored after transplantation.
  
  
  RESULTS
  The function of pancreas allograft was recovered immediately and the patient became insulin-independence postoperatively. The liver allograft was experienced an acute rejection episode and reversed by intravenous bolus methylprednisolone. The recipient was currently liver disease-free and insulin-free more than 21 months.
  
  
  CONCLUSIONS
  The simultaneous liver-pancreas-duodenum transplantation is an effective method in the treatment of end-stage liver disease and type-I diabetes mellitus.
authors.affiliation: Department of Organ Transplantation, Nanfang Hospital, The Southern Medical University, Guangzhou 510515, China. Xujian@fimmu.com
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Yu
authors.forename: Wen-feng
authors.initials: WF
authors.lastname: Deng
authors.forename: Shao-jie
authors.initials: SJ
authors.lastname: Fu
authors.forename: Chuan-fu
authors.initials: CF
authors.lastname: Du
authors.forename: Yi-bin
authors.initials: YB
authors.lastname: Wang
authors.forename: Xiao-you
authors.initials: XY
authors.lastname: Liu
authors.forename: Yun
authors.initials: Y
authors.lastname: Miao
authors.forename: Chuan-jiang
authors.initials: CJ
authors.lastname: Li
authors.forename: Jun-sheng
authors.initials: JS
authors.lastname: Ye
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000601:surgery*; D004386:Duodenum / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008103:Liver Cirrhosis / Q000150:complications / Q000601:surgery*; D008113:Liver Neoplasms / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation; D014184:Transplantation, Homologous
chemical_list: D007166:Immunosuppressive Agents