Development of soft-based double-stranded peptide chelators which selectively separate europium and lanthanum ions based on the hardness concept.
New double-stranded peptide chelators (1) conjugated Cat (2,3-dihydroxybenzoic acid) were synthesized and formed a molecular complex 1-Eu(3+) (or 1-Lu(3+)) with Eu(3+) and Lu(3+) but not La(3+). The double-stranded peptide chelator may prove to be useful tools for studying the selective separation of lanthanide ions.
Kobayashi
Shigeki
S
Department of Analytical Chemistry of Medicines, Showa Pharmaceutical University,3-3165 Higashi-tamagawagakuen, Machida, Tokyo 194-8543, Japan.
Mizushima
Atuhiro
A
Sasuga
Asako
A
Watanabe
Makoto
M
D000465:Algorithms; D002614:Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry; D004583:Electrons; D005063:Europium / Q000302:isolation & purification*; D007202:Indicators and Reagents; D007811:Lanthanum / Q000302:isolation & purification*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D011487:Protein Conformation; D016339:Spectrometry, Mass, Fast Atom Bombardment
D002614:Chelating Agents; D007202:Indicators and Reagents; D010455:Peptides; D005063:Europium; D007811:Lanthanum