Pseudoporphyria secondary to narrowband UVB phototherapy for psoriasis.
A 59-year-old woman undergoing narrowband UVB phototherapy for treatment of psoriasis presented suddenly with tense blisters on both hips. The blisters were asymptomatic and disappeared within 24 hours. Histopathology together with a negative porphyrin screen made the diagnosis of pseudoporphyria. Blood tests including a full blood count, urea and electrolytes, liver function tests and antinuclear autoantibodies were normal. The patient was otherwise healthy; there was no history of extensive sun exposure, sunbeds or medication with non-steroidal anti-inflammatory drugs. This presentation of pseudoporphyria secondary to narrowband UVB radiation is unusual, as UVB radiation is not known to be associated with pseudoporphyria.
Oh
Carol
C
Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Ireland. caroloh@bigpond.net.au
Jones
Brad
B
Solomon
Rustum
R
Egan
Conleth A
CA
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D011164:Porphyrias / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D011565:Psoriasis / Q000473:pathology / Q000532:radiotherapy*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014467:Ultraviolet Therapy / Q000009:adverse effects*