New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy.
Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much effort, the underlying factors that are responsible for it are poorly understood. In this review, we focus on some recent advances in our understanding of the pathogenesis of insulin resistance in humans that have been made using magnetic resonance spectroscopy.
Petersen
Kitt Falk
KF
Department of Medicine, Yale University School of Medicine, New Haven, CT 06536-8012, USA. kitt.petersen@yale.edu
Shulman
Gerald I
GI
D001786:Blood Glucose / Q000378:metabolism; D002149:Energy Intake / Q000502:physiology; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D018482:Muscle, Skeletal / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology
D001786:Blood Glucose; D005227:Fatty Acids