Lipedematous alopecia of the scalp.
Lipedematous scalp is a rare disorder, mainly described in adult African-American females. We report 2 adult caucasian males with lipedematous scalp associated with androgenetic alopecia. Patients were studied by dermoscopy and histopathology; they were treated with finasteride 1 mg. In our patients, lipedematous scalp affected the occipital and the vertex areas and pathologically exhibited mild edema and thickening of the adipose subcutaneous layer. At videodermoscopy, lipedematous scalp areas showed linear areas of teleangiectasia within the scalp creases, possibly caused by compression of the superficial blood capillaries by the increased volume of the subcutaneous fat layer within the thickened scalp. Finasteride at a dose of 1 mg per day for 1 year induced mild improvement of androgenetic alopecia in one patient and stabilization of the disease in the other. The lipedematous scalps remain unchanged. Lipedematous scalp is apparently a rare disease even though the condition is probably underdiagnosed. As a matter of fact, we diagnosed lipedematous scalp in our patients during a clinical examination for androgenetic alopecia, which was the patients' complaint. The association of lipedematous scalp and androgenetic alopecia in our two patients appears to be coincidental.
Piraccini
Bianca Maria
BM
Department of Dermatology, University of Bologna, Via Massarenti 1, 40138-Bologna, Italy.
Voudouris
Stylianos
S
Pazzaglia
Massimiliano
M
Rech
Giulia
G
Vicenzi
Colombina
C
Tosti
Antonella
A
D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000627:therapeutic use; D000273:Adipose Tissue; D000505:Alopecia / Q000188:drug therapy / Q000209:etiology*; D018120:Finasteride / Q000627:therapeutic use; D006801:Humans; D008068:Lipomatosis / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012536:Scalp Dermatoses / Q000150:complications* / Q000473:pathology; D044465:White People
D018120:Finasteride; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase