Endometrial polyp with sex cord-like pattern.
We report on an unusual endometrial polyp in a postmenopausal woman taking tamoxifen for 7 years after surgical resection of a breast carcinoma. A 63-year-old woman with endometrial thickening was submitted to hysteroscopy with biopsy, which revealed a polyp with a sex cord-like pattern. The hysterectomy specimen showed florid adenomyosis, and in the background, there were rare sex cord-like foci. Immunohistochemistry can be useful in differentiating sex cord-like elements from metastatic breast cancer to endometrium. This is, to our knowledge, the first observation in literature correlated to tamoxifen intake.
De Quintal
Maísa Momesso
MM
Department of Anatomic Pathology, Faculty of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil.
De Angelo Andrade
Liliana Aparecida Lucci
LA
D000071443:12E7 Antigen; D015703:Antigens, CD / Q000032:analysis; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D015815:Cell Adhesion Molecules / Q000032:analysis; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011127:Polyps / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D013629:Tamoxifen / Q000009:adverse effects / Q000627:therapeutic use; D014746:Vimentin / Q000032:analysis
D000071443:12E7 Antigen; D015703:Antigens, CD; D018931:Antineoplastic Agents, Hormonal; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D014746:Vimentin; D013629:Tamoxifen