[The rule of proliferation after sciatic injury of rats: immunohistological observation].
OBJECTIVE
To describe the rule of the schwann cell proliferation after peripheral nerve injury in detail and to discover the effect of neuroanastomosis.


METHODS
The model of rat sciatic injury was made, with neuroanastomosis on the left side and right side untreated. Then draw the materials 24, 48 h, 4, 7, 14, 21 d after surgery. And immunohistological stain counted the schwann cell per view with Qwin software of Leica Ltd.


RESULTS
The number of schwann cell increased obviously 4 d after surgery and reached the peak in 7 d. Then it fell down and the neuroanastomosis group changed slower and fibroblast hyperplasia in the untreated.


CONCLUSIONS
The axon support is essential for the schwann cell. The precise rule is help for study on neurotrophic factor.
Zhao
Fu-qiang
FQ
Department of Trauma and Orthopedics, People's Hospital, Peking University, Beijing 100044, China.
Jiang
Bao-guo
BG
Zhang
Pei-xun
PX
Zhang
Hong-bo
HB
D000714:Anastomosis, Surgical; D000818:Animals; D049109:Cell Proliferation; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012583:Schwann Cells / Q000166:cytology*; D012584:Sciatic Nerve / Q000293:injuries* / Q000473:pathology / Q000601:surgery*; D013997:Time Factors