Antimicrobial potentiality of Phyllanthus amarus against drug resistant pathogens.
The antimicrobial potentiality of the methanolic extract of Phyllanthus amarus (Family: Euphorbiaceae) was studied against some drug resistant pathogenic bacterial strains by disc diffusion and agar dilution method. The extract showed significant concentration-dependent antibacterial activity particularly against gram-negative microbes. The study illustrated the claim of the usefulness of the plant in dysenteric and diarrheal infections and also suggested its use in fever. The antibacterial action was mainly due to the isolated phyllanthin.
Mazumder
Avijit
A
Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi - 835 215, India. avijitmazum@yahoo.com
Mahato
Arun
A
Mazumder
Rupa
R
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D024881:Drug Resistance, Bacterial; D029803:Phyllanthus / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010936:Plant Extracts