Hemolytic uremic syndrome associated with invasive Streptococcus pneumoniae infection: report of one case.
Hemolytic uremic syndrome (HUS) most commonly follows an episode of gastroenteritis associated with Escherichia coli (O157:H7). S. pneumoniae-associated HUS is rare and has been reported having a high morbidity and mortality rate. We present a 1-year-5-month-old girl who developed S. pneumoniae-associated HUS and positive T-activation testing. She received antibiotics, washed red blood cell transfusion and early continuous venovenous hemodiafiltration treatment. She had chronic renal failure but was without other sequelae after 8 months, follow-up. Early dialysis intervention in S. pneumoiae-induced HUS patients decreasing the morbidity and mortality rate is discussed, and the literature is reviewed.
Ou
Chun-Yen
CY
Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chiou
Yee-Hsuan
YH
Chang
Jenn-Tzong
JT
Chiu
Ching-Lan
CL
Shih
Chen-Hung
CH
Hsieh
Kai-Sheng
KS
D005260:Female; D017583:Hemodiafiltration; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D007223:Infant; D008213:Lymphocyte Activation; D011008:Pneumococcal Infections / Q000150:complications* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology