title: Treatment of invasive squamous cell carcinoma with 5-percent imiquimod cream.
abstract: Skin cancer is a major problem in the elderly. Squamous cell carcinoma (SCC), the second most common skin cancer, typically occurs in this age group. Despite a number of modalities readily available for treatment (depending on the tumor site, and depth of invasion) there remains the problem of individuals with multiple lesions who may be unsuitable for existing treatments for SCC, particularly surgery. Consequently, the search for novel treatments continues. To our knowledge, there are only 6 published reports of invasive SCC treated with 5-percent imiquimod cream.
authors.affiliation: Department of Dermatology and Pathology, Ysbyty Gwynedd Hospital, Bangor, LL57 2PW, UK. Maria.Konstantopopoulou@nww-tr.wales.nhs.uk
authors.forename: M
authors.initials: M
authors.lastname: Konstantopoulou
authors.forename: M G
authors.initials: MG
authors.lastname: Lord
authors.forename: A W
authors.initials: AW
authors.lastname: Macfarlane
mesh_terms: D000369:Aged, 80 and over; D000634:Aminoquinolines / Q000008:administration & dosage* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D000077271:Imiquimod; D009361:Neoplasm Invasiveness; D009824:Ointments; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D009824:Ointments; D000077271:Imiquimod