title: Geographical information system (GIS) in investigation of an outbreak.
abstract: An outbreak of fever in a village in southern India was reported on 1st September, 2001. The first reported case presented with epistaxis and a platelet count of 27000h(1)/mm3. Clinical, laboratory and entomological evidence supported a diagnosis of dengue fever. One third of the village was affected and 3.7 % of the population presented with haemorrhagic symptoms; none were fatal. Five acute cases tested for dengue specific IgM showed that two were positive. The larvae of Aedes aegypti were discovered from domestic water collections in the village. Spatial analysis done with the help of Geographical Information Systems software (GIS) demonstrated a centrifugal spread of cases from the most affected street until it involved the entire village. Spatial analysis revealed that cases occurred in clusters and that these could not have occurred by chance. This was our first experience in producing a geo-referenced map of a village area and in spatial analysis. GIS is a novel and simple tool for outbreak investigations and the spatial analyst adds additional information to the data collected. Control of adult mosquitoes and larvae prevented the outbreak from spreading to an adjacent village.
authors.affiliation: Dept of Community Health, Christian Medical College, Vellore, India.
authors.forename: V
authors.initials: V
authors.lastname: Nisha
authors.forename: Santosh S
authors.initials: SS
authors.lastname: Gad
authors.forename: David
authors.initials: D
authors.lastname: Selvapandian
authors.forename: V
authors.initials: V
authors.lastname: Suganya
authors.forename: V
authors.initials: V
authors.lastname: Rajagopal
authors.forename: Pearlin
authors.initials: P
authors.lastname: Suganti
authors.forename: V
authors.initials: V
authors.lastname: Balraj
authors.forename: Jayanth
authors.initials: J
authors.lastname: Devasundaram
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000453:epidemiology* / Q000503:physiopathology / Q000517:prevention & control; D019223:Densovirinae; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009032:Mosquito Control