title: [Liver transplantation for treating hepatocellular carcinoma].
abstract: OBJECTIVE
  To evaluate the role of orthotopic liver transplantation (OLT) in treating hepatocellular carcinoma (HCC).
  
  
  METHODS
  Data of 92 consecutive orthotopic liver transplantations (OLTs) performed during January 1999 and February 2005 at our institution were analyzed.
  
  
  RESULTS
  Of the 92 recipients, 8 HCC patients were stage I, 13 were stage II, 12 stage III and 59 stage IV (UICC TNM staging system). Overall 1-, 2-, 3-, 5-year patient survival rates were 65.3%, 27.0%, 20.0%, and 6.9%, respectively. When OLT indications were considered, best recipients survival was obtained in stage I patients (100.0%, 100.0%, 66.7%, and 50.0% at 1, 2, 3, and 5 years, respectively) and stage II patients (85.7%, 66.7%, and 66.7% at 1, 2 and 3 years, respectively). Whereas, 1, 2, 3 and 5-year recipients survival rates were 50.0%, 0, 0, 0 in stage III patients, and 58.1%, 20.0%, 13.0% and 5.0% in stage IV patients.
  
  
  CONCLUSIONS
  The prognosis of different stages of HCC patients who underwent OLT was significantly different. The OLT recipients with HCC should be strictly selected. Long-term recipient survival could be obtained in stage I and stage II patients.
authors.affiliation: Hepatobiliary Surgery Institute of PLA, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiang-de
authors.initials: XD
authors.lastname: Liu
authors.forename: Zhan-yu
authors.initials: ZY
authors.lastname: Yang
authors.forename: Shu-guang
authors.initials: SG
authors.lastname: Wang
authors.forename: Ping
authors.initials: P
authors.lastname: Bie
authors.forename: Shu-guo
authors.initials: SG
authors.lastname: Zheng
authors.forename: Lei-da
authors.initials: LD
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: He
authors.forename: Qian
authors.initials: Q
authors.lastname: Lu
authors.forename: Zhi-qing
authors.initials: ZQ
authors.lastname: Yang
authors.forename: Jia-hong
authors.initials: JH
authors.lastname: Dong
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery*; D016031:Liver Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015996:Survival Rate