title: Impact of sex-specific body composition on cardiovascular risk factors: the Hong Kong Cardiovascular Risk Factor Study.
abstract: The aim of the study was to analyze the effects of sex-specific distribution of adiposity, particularly emphasizing the independent contribution of waist and hip circumferences relative to body mass index (BMI), on cardiovascular risk factors in a Chinese population. Blood pressure and anthropometric and biochemical parameters were measured in 2510 population-based Chinese subjects. The relative contributions of waist and hip circumferences to the presence of cardiovascular risk factors were determined. The Chinese men were significantly larger than women, with greater BMI and central adiposity. Waist and hip circumferences were both positively associated with the presence of hypertension, dyslipidemia, and diabetes. However, after adjustment for BMI and age, hip circumference exhibited a significant dose-dependent inverse relationship with dyslipidemia and diabetes in women, but not men. Sex-specific differences exist. After adjustment for age and BMI, hip circumferences independently and inversely contribute to cardiovascular risk in women, but not in men. Increasing adjusted waist circumference was associated with increased risk of hypertension and diabetes in Chinese and dyslipidemia in women only.
authors.affiliation: Department of Community Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
authors.forename: G Neil
authors.initials: GN
authors.lastname: Thomas
authors.forename: Sarah M
authors.initials: SM
authors.lastname: McGhee
authors.forename: Mary
authors.initials: M
authors.lastname: Schooling
authors.forename: Sai Yin
authors.initials: SY
authors.lastname: Ho
authors.forename: Karen S L
authors.initials: KS
authors.lastname: Lam
authors.forename: Edward D
authors.initials: ED
authors.lastname: Janus
authors.forename: Tai Hing
authors.initials: TH
authors.lastname: Lam
mesh_terms: D050153:Abdominal Fat / Q000502:physiology*; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism; D050171:Dyslipidemias / Q000503:physiopathology; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D006943:Hyperglycemia / Q000503:physiopathology; D006973:Hypertension / Q000503:physiopathology; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000503:physiopathology; D012307:Risk Factors; D012737:Sex Factors; D049629:Waist-Hip Ratio