title: Extended-spectrum beta-lactamases and plasmid-mediated AmpC enzymes among clinical isolates of Escherichia coli and Klebsiella pneumoniae from seven medical centers in Taiwan.
abstract: Production of extended-spectrum beta-lactamases and plasmid-mediated AmpC enzymes was investigated among 291 Escherichia coli and 282 Klebsiella pneumoniae isolates that showed decreased susceptibilities to extended-spectrum cephalosporins from seven Taiwanese medical centers. CTX-M-type and SHV-type enzymes were the most prevalent extended-spectrum beta-lactamases. CMY-2-like and DHA-1-like beta-lactamases were the most prevalent AmpC-type enzymes.
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, No. 1 University Road, Tainan, Taiwan 70101.
authors.forename: Jing-Jou
authors.initials: JJ
authors.lastname: Yan
authors.forename: Po-Ren
authors.initials: PR
authors.lastname: Hsueh
authors.forename: Jang-Jih
authors.initials: JJ
authors.lastname: Lu
authors.forename: Feng-Yee
authors.initials: FY
authors.lastname: Chang
authors.forename: Jainn-Ming
authors.initials: JM
authors.lastname: Shyr
authors.forename: Jen-Hsien
authors.initials: JH
authors.lastname: Wan
authors.forename: Yung-Ching
authors.initials: YC
authors.lastname: Liu
authors.forename: Yin-Ching
authors.initials: YC
authors.lastname: Chuang
authors.forename: Yi-Chueh
authors.initials: YC
authors.lastname: Yang
authors.forename: Shih-Ming
authors.initials: SM
authors.lastname: Tsao
authors.forename: Hsiu-Hung
authors.initials: HH
authors.lastname: Wu
authors.forename: Li-Shin
authors.initials: LS
authors.lastname: Wang
authors.forename: Tsuey-Pin
authors.initials: TP
authors.lastname: Lin
authors.forename: Hsiu-Mei
authors.initials: HM
authors.lastname: Wu
authors.forename: Hung-Mo
authors.initials: HM
authors.lastname: Chen
authors.forename: Jiunn-Jong
authors.initials: JJ
authors.lastname: Wu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000378:metabolism*; D002511:Cephalosporins / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology; D006761:Hospitals; D006801:Humans; D007710:Klebsiella Infections / Q000453:epidemiology / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D015995:Prevalence; D013624:Taiwan / Q000453:epidemiology; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002511:Cephalosporins; C048795:AmpC beta-lactamases; D001618:beta-Lactamases