Comparative analysis of the baseline spike activity of neurons in the fastigial nucleus of the cerebellum at different durations of exposure to vibration.
Acute experiments on Nembutal-anesthetized (40 mg/kg, i.p.) white rats with extracellular recording and analysis of baseline spine activity of neurons in the fastigial nucleus of the cerebellum were performed in normal conditions and after exposure to vibration for 5, 10, and 15 days. The distribution of neurons in terms of the regularity and dynamics of spike flows and the modality of interspike interval histograms were determined, along with the mean neuron spike frequency and the coefficient of variation of interspike intervals. The results showed that the most significant changes in neuron activity in fastigial nucleus cells were formed during the first ten days of vibration. On day 15, there was a tendency for measures to return to control levels.
Saakyan
S G
SG
Department of Human and Animal Physiology, Erevan State University, Armenia.
Kazaryan
A K
AK
Grigoryan
G Yu
GY
Minasyan
S M
SM
Sarkisyan
R Sh
RSh
D000200:Action Potentials / Q000502:physiology; D000222:Adaptation, Physiological; D000818:Animals; D002529:Cerebellar Nuclei / Q000166:cytology / Q000502:physiology*; D005071:Evoked Potentials / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D051381:Rats; D013997:Time Factors; D014732:Vibration