Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage.
Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative stress in these organisms can give important information about their physiological status and also about environmental health. Bivalves have been proposed as good sentinel organisms in pollution monitoring studies through the analysis of biochemical biomarkers, and most of the biomarkers analyzed are those related to oxidative stress. However, it is very important to know how other environmental factors not associated to the presence of pollutants might affect these parameters. We have studied a series of mechanisms related to oxidative stress in mussels which inhabit the Brazilian coast, especially in Perna perna species, subjected to different stress conditions, such as the exposure to different contaminants in the laboratory and in the field, the exposure of mussels to air and re-submersion, simulating the tidal oscillations, and in mussels collected at different seasons. Both oxidative damage levels and antioxidant defense systems were strongly affected by the different environmental stress. This review summarizes the data obtained in some studies carried out in bivalves from the Brazilian coast.
Alves de Almeida
Eduardo
E
Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, CP 26.077, 05513-970, São Paulo, Brazil.
Celso Dias Bainy
Afonso
A
Paula de Melo Loureiro
Ana
A
Regina Martinez
Glaucia
G
Miyamoto
Sayuri
S
Onuki
Janice
J
Fujita Barbosa
Lívea
L
Carrião Machado Garcia
Camila
C
Manso Prado
Fernanda
F
Eliza Ronsein
Graziella
G
Alexandre Sigolo
Carlos
C
Barbosa Brochini
Cláudia
C
Maria Gracioso Martins
Ana
A
Helena Gennari de Medeiros
Marisa
M
Di Mascio
Paolo
P
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D049872:Bivalvia / Q000502:physiology*; D001938:Brazil; D004249:DNA Damage; D004463:Ecology; D015227:Lipid Peroxidation; D008386:Marine Biology; D018384:Oxidative Stress; D049883:Perna / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism
D000975:Antioxidants; D017382:Reactive Oxygen Species