Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome.
OBJECTIVE
To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) and polycystic ovary syndrome (PCOS).


METHODS
Case report.


METHODS
University department of obstetrics and gynecology, Italy.


METHODS
A woman complaining of RM who had PCOS and insulin resistance.


METHODS
Clinical, biochemical, and instrumental assessments.


METHODS
Administration of metformin hydrochloride before and throughout pregnancy.


RESULTS
After 3 months of treatment, the patient became pregnant. The pregnancy had a physiologic development, and at 39 weeks of gestation, the patient spontaneously delivered a healthy infant.


CONCLUSIONS
Metformin has shown to be effective in an insulin-resistant PCOS woman with RM.
Palomba
Stefano
S
Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Italy. stefanopalomba@tin.it
Falbo
Angela
A
Orio
Francesco
F
Russo
Tiziana
T
Tolino
Achille
A
Zullo
Fulvio
F
D000026:Abortion, Habitual / Q000517:prevention & control*; D000328:Adult; D016640:Diabetes, Gestational / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D008687:Metformin / Q000008:administration & dosage*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy*; D011247:Pregnancy; D016896:Treatment Outcome
D007004:Hypoglycemic Agents; D008687:Metformin