Cutaneous, pulmonary and hepatic sarcoidosis associated with autoimmune complications during interferon-alpha treatment for hepatitis C virus infection.
A patient with hepatitis C virus (HCV) infection was diagnosed with cutaneous, pulmonary and hepatic sarcoidosis following interferon alpha therapy. There are only a few cases of sarcoidosis associated with this treatment. This is the first case who not only developed sarcoidosis, but also autoimmune hypothyroidism and thrombocytopenia during interferon alpha therapy due to the immunomodulatory effects of the drug.
Akay
B N
BN
Department of Dermatology, Ankara University School of Medicine, Ankara, Turkey.
Ekmekci
P
P
Sanli
H
H
Celik
G
G
Bozdayi
M
M
D000998:Antiviral Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D012507:Sarcoidosis / Q000139:chemically induced*; D013921:Thrombocytopenia / Q000139:chemically induced
D000998:Antiviral Agents; D016898:Interferon-alpha