Cardiac surgery in a patient with haemophilia A.
In this report we describe the successful cardiac surgery in a patient with haemophilia A. To undergo to triple on-pump coronary artery bypass grafting the level of factor VIII was estimated to be 100 %, during the operation and the first postoperative week. To reach this level, bolus therapy with B-domain deleted recombinant factor VIII was administered in a low substitution scheme. There was no bleeding complication. The patient discharged on the 14th postoperative day.
Eren
A
A
Department of Cardiac Surgery, University Hospital Ulm, Ulm, Germany. aidaeren@gmx.de
Friedl
R
R
Hannekum
A
A
Gulbins
H
H
D000789:Angina, Unstable / Q000150:complications / Q000601:surgery; D015415:Biomarkers / Q000097:blood; D003131:Combined Modality Therapy; D001026:Coronary Artery Bypass; D023921:Coronary Stenosis / Q000150:complications* / Q000601:surgery*; D005169:Factor VIII / Q000378:metabolism / Q000627:therapeutic use; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000601:surgery
D015415:Biomarkers; D005169:Factor VIII