title: Irregularities on the surface of single-piece AcrySof SA60AT intraocular lenses.
abstract: OBJECTIVE
  To report a case series of what initially appeared to be macroscopic biomaterial deposits and irregularities on the surface of AcrySof SA60AT intraocular lenses (IOLs) (Alcon Inc.)
  
  
  METHODS
  Department of Ophthalmology and Somerset Hospital, Taunton, United Kingdom; Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; and Intraocular Implant Unit, Sydney Eye Hospital, University of Sydney, Sydney, Australia.
  
  
  METHODS
  Twelve AcrySof SA60AT IOLs were initially thought to have irregularities on their surfaces when examined under the operating microscope before implantation in the capsular bag during cataract surgery. The IOLs were sent for further analysis, including gross examination and light and scanning electron microscopy, to John A. Moran Eye Center, Salt Lake City, Utah, USA, and to Alcon Laboratories, Hemel Hempstead, United Kingdom.
  
  
  RESULTS
  Light microscopy revealed the presence of irregular fine lesions on the IOLs' optics and haptics. The lesions consisted of elevations and depressions of the IOL surface that were present on both the anterior and the posterior surfaces of the IOLs. Scanning electron microscopy confirmed the presence of physical/mechanical damage to the IOLs, which was thought to originate from the packaging. The manufacturer believed this to have resulted from compression of the IOL between the container and its cover.
  
  
  CONCLUSIONS
  Implantation of an imperfect IOL remains a potentially serious occurrence. Faults still occur in modern IOLs, and some defects can be detected by examining the IOL under the operating microscope before implantation into the eye.
authors.affiliation: Department of Ophthalmology, Taunton and Somerset Hospital, Taunton, United Kingdom.
authors.forename: Dan Q
authors.initials: DQ
authors.lastname: Nguyen
authors.forename: Tarek A
authors.initials: TA
authors.lastname: Saleh
authors.forename: Suresh K
authors.initials: SK
authors.lastname: Pandey
authors.forename: Adrian K
authors.initials: AK
authors.lastname: Bates
mesh_terms: D000180:Acrylic Resins; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008855:Microscopy, Electron, Scanning; D018918:Phacoemulsification; D011475:Prosthesis Failure; D013499:Surface Properties
chemical_list: D000180:Acrylic Resins