title: Cartilaginous and osseous metaplasia with bone marrow formation in the aortic valve of a patient with giant cell aortitis.
abstract: We describe the case of a 40-year-old man who presented with an ascending aortic aneurysm and aortic valve regurgitation. The patient underwent a Bentall surgical procedure. Pathologic findings were consistent with giant cell aortitis with synchronous cartilaginous and osseous metaplasia with bone marrow formation in the degenerated aortic valve. The coexistence of these findings has not been previously reported in the English language literature.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, AHEPA University Hospital, Aristotelian University of Thessaloniki, Thessaloniki, Greece. charokoposnick@hotmail.com
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Charokopos
authors.forename: Polichronis
authors.initials: P
authors.lastname: Antonitsis
authors.forename: Efthymia
authors.initials: E
authors.lastname: Rouska
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kostopoulos
authors.forename: Adnan
authors.initials: A
authors.lastname: Charaf
authors.forename: Panagiotis K
authors.initials: PK
authors.lastname: Spanos
mesh_terms: D000328:Adult; D001011:Aorta / Q000473:pathology; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging / Q000453:epidemiology*; D001021:Aortic Valve / Q000473:pathology*; D001022:Aortic Valve Insufficiency / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D001853:Bone Marrow / Q000473:pathology*; D002114:Calcinosis / Q000453:epidemiology* / Q000473:pathology; D002356:Cartilage / Q000473:pathology*; D015897:Comorbidity; D013700:Giant Cell Arteritis / Q000453:epidemiology* / Q000473:pathology; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008679:Metaplasia; D014057:Tomography, X-Ray Computed