[Computer-aided mandibular repositioning system for efficacy prediction of oral appliance in patients with obstructive sleep apnea-hypopnea syndrome].
OBJECTIVE
To develop a computer-aided mandibular repositioning system (CAMRS) and investigate its preliminary application in efficacy prediction of oral appliance in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).


METHODS
CAMRS was mainly consisting of a step motor and a screw that was remote-controlled by a computer. This system could work with polysomnography (PSG). Fourteen OSAHS patients diagnosed by PSG were recruited. With CAMRS, six mandibular positions were titrated with PSG for every hour.


RESULTS
Stable mandible positioning and little sleeping disturbance were observed. Apnea hypopnea index (AHI) was improved progressively with mandibular advancement. The extent of mandibular advancement was correlated with the severity of OSAHS (r = 0.72747).


CONCLUSIONS
CAMRS could reproductively and effectively reposition mandible with little sleeping disturbance. Through CAMRS, an individualized optimal mandibular position could be obtained for each OSAHS patient treated with oral appliance.
Liu
Yue-hua
YH
Department of Orthodontics, School of Stomatology, Tongji University, Shanghai 200072, China. joshua66@126.com
Zhao
Xiao-guang
XG
Xu
Bao-fu
BF
Li
Juan
J
Lu
Min-xun
MX
D000328:Adult; D000368:Aged; D017076:Computer-Aided Design; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000628:therapy*; D016896:Treatment Outcome