title: Complete cytoreduction combined with early postoperative intraperitoneal chemotherapy for ovarian carcinosarcoma. Report of two cases.
abstract: OBJECTIVE
  The purpose of the study is to report two long-term survivors with ovarian carcinosarcomas, which are rare intrapelvic malignancies with unfavorable prognosis.
  
  
  METHODS
  Two middle-aged women with palpable abdominal tumors underwent complete cytoreductive surgery and no macroscopic tumor was left behind. Early postoperative intraperitoneal chemotherapy with doxorubicin was used as an adjuvant treatment.
  
  
  RESULTS
  The patients are disease-free 2 and 3 years, respectively after the initial therapy.
  
  
  CONCLUSIONS
  Complete cytoreduction combined with early postoperative intraperitoneal chemotherapy seems to be an effective treatment for ovarian carcinosarcoma with peritoneal spread. Further studies are required to define the value of intraperitoneal chemotherapy in ovarian carcinosarcoma.
authors.affiliation: Department of Surgery, Didimotichon General Hospital, Didimotichon, Greece. dr_xanthoulis@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Xanthoulis
authors.forename: Charalambos
authors.initials: C
authors.lastname: Mirelis
authors.forename: Sotirios
authors.initials: S
authors.lastname: Markakidis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Bougioukas
authors.forename: Konstantina
authors.initials: K
authors.lastname: Bekiaridou
authors.forename: Evanthia
authors.initials: E
authors.lastname: Tsalkidou
authors.forename: Georgios
authors.initials: G
authors.lastname: Zafeiropoulos
authors.forename: Antonios-Apostolos K
authors.initials: AA
authors.lastname: Tentes
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D002296:Carcinosarcoma / Q000188:drug therapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D004317:Doxorubicin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral / Q000379:methods; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery*; D011379:Prognosis; D017741:Survivors; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin