title: Linear lichen planus and hepatitis C.
abstract: A 23-year-old man with hepatitis C was observed with brownish dome-shaped papules in a linear pattern on the chest. The papules were determined clinically and pathologically to be linear lichen planus. These lesions appeared during an interferon-alpha therapy for his hepatitis and resolved after topical treatment with tacrolimus ointment. Linear lichen planus and hepatitis C have been reported only twice previously. The association between these disorders and the potential role of interferon therapy are discussed.
authors.affiliation: Department of Dermatology, San Cecilio Hospital, Granada, Spain. viviguiote@yahoo.es
authors.forename: María Victoria Guiote
authors.initials: MV
authors.lastname: Domínguez
authors.forename: Anna Vilanova
authors.initials: AV
authors.lastname: Mateu
authors.forename: Ricardo
authors.initials: R
authors.lastname: Vieira
authors.forename: Juan Linares
authors.initials: JL
authors.lastname: Solano
authors.forename: Ramón Naranjo
authors.initials: RN
authors.lastname: Sintes
authors.forename: María Teresa Gutiérrez
authors.initials: MT
authors.lastname: Salmerón
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D006526:Hepatitis C / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016898:Interferon-alpha / Q000009:adverse effects*; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D016898:Interferon-alpha; D016559:Tacrolimus