Magnesium urinary excretion in diabetic adolescents.
OBJECTIVE
To define peculiarities of urinary magnesium (Mg) excretion in diabetic adolecents; to elucidate gender-related differences in Mg urinary excretion; to determine urinary Mg excretion differences between diabetic and age-matched healthy children. The diurnal, nocturnal and 24-h urinary Mg level in adolescent boys and girls (aged 13-17 years) with type I diabetes mellitus (DM) and in age-matched control groups of healthy boys and girls was examined. Additionally the adolescent girls were examined during different phases of their menstrual cycle.


RESULTS
Diurnal, overnight and 24-h Mg urinary excretion in diabetic adolescent boys and girls was significantly higher than in healthy ones. In diabetic boys 24 h Mg excretion was higher than in diabetic girls (4.59 +/- 1.4 vs. 3.34 +/- 1.5 mmol; p < 0.05). The investigation showed gender-related differences in Mg urinary excretion in healthy adolescents: 24-h Mg urinary excretion was significantly higher in boys than in girls (2.66 +/- 0.9 vs. 2.1 +/- 0.9 mmol; p < 0.05). The level of Mg in the nocturnal urine of boys and girls was significantly higher than in diurnal. Urine Mg was negatively related to height in adolescent girls.


CONCLUSIONS
Diabetic adolescents excrete significantly more Mg with urine as compared to healthy ones.
Driziene
Zaneta
Z
Vilnius University, Centre of Pediatrics, Medical Faculty, Lithuania.
Stakisaitis
Donatas
D
Balsiene
Janina
J
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000652:urine*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000652:urine*; D008297:Male; D012727:Sex Characteristics
D008274:Magnesium