Erythromycin and clindamycin resistance in group B streptococcal clinical isolates.
Erythromycin (EM) and clindamycin (CM) susceptibility testing was performed on 222 clinical isolates of group B Streptococcus. A multiplex PCR assay was used to detect the ermB, ermTR, and mefA/E antibiotic resistance genes. These results were compared to the phenotypes as determined by the standard EM/CM double disk diffusion assay.
Gygax
Scott E
SE
Medical Diagnostic Laboratories, L.L.C., Department of Research and Development, 2439 Kuser Road, Hamilton, NJ 08690, USA.
Schuyler
Jessica A
JA
Kimmel
Lauren E
LE
Trama
Jason P
JP
Mordechai
Eli
E
Adelson
Martin E
ME
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D005798:Genes, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D013290:Streptococcal Infections / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D004917:Erythromycin