Furoquinoline alkaloids from Melicope bonwickii (F.Muell.) T.Hartley.
Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 and 2 showed significant activity against cervical cell lines (Hela).
Komala
Ismiarni
I
Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.
Rahmani
Mawardi
M
Sukari
Mohd Aspollah
MA
Mohd Ismail
Hazar Bebe
HB
Cheng Lian
Gwendoline Ee
GE
Rahmat
Asmah
A
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D011804:Quinolines / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D027821:Rutaceae / Q000737:chemistry* / Q000145:classification*
D000972:Antineoplastic Agents, Phytogenic; D011804:Quinolines