title: Asymmetric aziridination of 1,3-dienes catalyzed by bisoxazoline-copper complexes.
abstract: The asymmetric aziridination of 1,3-dienes catalyzed by bisoxazoline-CuOTf complexes with PhI=NTs as a nitrene precursor has been achieved in moderate yields with up to >99:1 regioselectivity, up to >99% diastereoselectivity, and up to 80% enantioselectivity. alpha,beta,gamma,delta-Unsaturated ketones usually produced cis-gamma,delta-aziridinated products, while 1,4-diphenyl-1,3-butadiene afforded both of cis- and trans-aziridine derivatives as major products by the use of different bisoxazoline ligands. The configuration of cis-aziridine derivatives was proposed on the basis of the reaction mechanism.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, P. R. China.
authors.forename: Linge
authors.initials: L
authors.lastname: Ma
authors.forename: Da-Ming
authors.initials: DM
authors.lastname: Du
authors.forename: Jiaxi
authors.initials: J
authors.lastname: Xu