[An experimental study on alveolar ridge preservation prior to dental implant placement].
OBJECTIVE
To evaluate the combination of surgical grade calcium sulfate hemihydrate (SGCS) and platelet-rich plasma (PRP) for alveolar ridge preservation prior to implant placement.


METHODS
Changes of bone quantity and quality in extraction sites following the SGCS/PRP and SGCS implantations were investigated by spiral computer tomography scan, bone scintigraphy, radiographic, histological and histomorphometric examinations.


RESULTS
The placement of SGCS/PRP reduced the resorption of the alveolar ridge. It also promoted bone metabolism and bone-to-implant contact. The addition of PRP to SGCS achieved the enhancement of the bone metabolism only at the early healing phase.


CONCLUSIONS
In this animal experiment, SGCS/PRP may be used as fresh extraction sockets graft for alveolar ridge preservation prior to implant placement.
Shi
Bin
B
Key Laboratory of Oral Biomedical Engineering of Ministry of Education, School of Stomatology, Wuhan University, Wuhan 430079, China.
Zhou
Yi
Y
Wang
Yi-ning
YN
Cheng
Xiang-rong
XR
D016301:Alveolar Bone Loss / Q000517:prevention & control*; D000539:Alveolar Process / Q000473:pathology / Q000601:surgery*; D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D002133:Calcium Sulfate / Q000627:therapeutic use*; D015921:Dental Implants; D004285:Dogs; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D016348:Osseointegration / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology; D053657:Platelet-Rich Plasma; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
D018786:Bone Substitutes; D015921:Dental Implants; D019275:Radiopharmaceuticals; D002133:Calcium Sulfate