title: Cucurbitacin glucosides from Citrullus colocynthis.
abstract: A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species.
authors.affiliation: International Center for Chemical Sciences, HEJ, Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
authors.forename: Durey
authors.initials: D
authors.lastname: Nayab
authors.forename: Dildar
authors.initials: D
authors.lastname: Ali
authors.forename: Nuzhat
authors.initials: N
authors.lastname: Arshad
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: M Iqbal
authors.initials: MI
authors.lastname: Choudhary
authors.forename: Zaheer
authors.initials: Z
authors.lastname: Ahmed
mesh_terms: D029773:Citrullus; D054728:Cucurbitacins; D005638:Fruit; D005960:Glucosides / Q000737:chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry
chemical_list: D005960:Glucosides; D010936:Plant Extracts; D014315:Triterpenes; D054728:Cucurbitacins