Moyamoya syndrome with primary antiphospholipid syndrome.
OBJECTIVE
To report a rare case of moyamoya syndrome with primary antiphospholipid syndrome (APS).


METHODS
A 41-year-old woman was admitted with sudden onset of left-sided hemiparesis. Magnetic resonance imaging and magnetic resonance angiography of the brain showed characteristic features of moyamoya vessels. Laboratory investigations revealed raised levels of anticardiolipin antibody. She made a complete and uneventful recovery with aspirin and intensive physiotherapy over a period of 2 weeks.


CONCLUSIONS
The association of APS and moyamoya disease may present a dilemma in management. While APS is often considered to be an indication for giving anticoagulation, a trial of antiplatelet agents is preferable to anticoagulation because of the risk of bleeding from the fragile moyamoya vessels.
Shuja-Ud-Din
Mohammed Ali
MA
Department of Medicine, Al-Sabah Hospital, Kuwait. shujadr@hotmail.com
Ahamed
Shefeek Abubacker
SA
Baidas
Ghassan
G
Naeem
Mohammad
M
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy