title: Morphine-associated pruritus after single extradural administration in a horse.
abstract: Pruritus following a single administration of 100 microg kg(-1) of preservative-free morphine sulphate given via an extradural catheter was seen in a 580 kg horse. The catheter was placed in the first intercoccygeal space. Focal irritation, represented by both local alopecia over the left gluteal muscles and serum exudation, occurred 4-8 hours after injection. This was attributed to the extradural morphine administration.
authors.affiliation: Department of Veterinary Clinical Services, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, UK.
authors.forename: John H
authors.initials: JH
authors.lastname: Burford
authors.forename: Kevin T T
authors.initials: KT
authors.lastname: Corley
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D000768:Anesthesia, General / Q000662:veterinary; D000818:Animals; D003937:Diagnosis, Differential; D006734:Horse Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D006736:Horses / Q000502:physiology / Q000601:surgery; D007268:Injections, Epidural / Q000662:veterinary; D007794:Lameness, Animal / Q000601:surgery; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000009:adverse effects*; D011537:Pruritus / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine