title: Levodopa-responsive parkinsonism associated with hydrocephalus.
abstract: We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.
authors.affiliation: Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
authors.forename: Mi Jung
authors.initials: MJ
authors.lastname: Kim
authors.forename: Sun J
authors.initials: SJ
authors.lastname: Chung
authors.forename: Young H
authors.initials: YH
authors.lastname: Sung
authors.forename: Myoung C
authors.initials: MC
authors.lastname: Lee
authors.forename: Joo-Hyuk
authors.initials: JH
authors.lastname: Im
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications*; D007980:Levodopa / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000188:drug therapy*
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa