title: Outcome of LASIK for myopia in women on hormone replacement therapy.
abstract: OBJECTIVE
  To investigate the effect of hormone treatment on refractive and visual outcome after LASIK in women.
  
  
  METHODS
  A retrospective review of the hospital notes of all women on hormone replacement therapy (HRT) and oral contraceptives at the time of LASIK was performed. Their refractive and visual outcomes were compared with those of women not on hormone treatment.
  
  
  RESULTS
  At 6 months after LASIK, 20 (45%) HRT eyes and 61 (75%) control eyes had a visual acuity of > or = 20/20. Thirty-six (82%) eyes from the HRT group and 74 (91%) eyes from the control group could see > or = 20/40. A statistically significant difference was noted in both refractive and visual outcome in women taking HRT at the time of surgery in comparison to controls. Women on the oral contraceptive pill did not differ in outcome from controls.
  
  
  CONCLUSIONS
  Women on HRT are at an increased risk of refractive regression after LASIK.
authors.affiliation: Mater Private Hospital, Dublin, Ireland.
authors.forename: Maeve A
authors.initials: MA
authors.lastname: O'Doherty
authors.forename: John V
authors.initials: JV
authors.lastname: O'Doherty
authors.forename: Michael
authors.initials: M
authors.lastname: O'Keefe
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D020249:Hormone Replacement Therapy; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D017698:Postmenopause; D012029:Refraction, Ocular; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity