title: [Visual and histologic analysis of laparoscopic diagnosis of endometriosis].
abstract: OBJECTIVE
  To determine the characteristics of anatomical distribution of pelvic endometriosis and the correlation between visual and histologic findings of endometriosis at laparoscopy.
  
  
  METHODS
  A prospective study of 62 patients undergoing laparoscopy for the pelvic pain, infertility and/or pelvic masses was carried out. All lesions with the diagnosis of endometriosis laparoscopically were excised and examined pathologically. Normal-appearing peritoneal biopsies were obtained randomly. All lesions were identified by anatomical site and color of the foci. The positive predictive value (PPV), sensitivity, negative predictive value (NPV), and specificity were determined for visually identified endometriosis versus the histologic findings.
  
  
  RESULTS
  Totally, 219 peritoneal endometriotic lesions, 54 normal peritoneal biopsies, and 71 ovarian endometriotic cysts were obtained. Peritoneal lesions tended to locate in posterior part of the pelvis (80.8%, 177/219) and in left (58.0%, 127/219) with most in black (39.2%). The PPV was 67.6%; sensitivity, 93.7%; NPV, 81.4%; and specificity, 38.3% for visual versus histologic diagnosis of peritoneal endometriosis. Lesions in black or from sacral ligaments were confirmed histologically in 94.2% and 84.7% respectively, and 80.3% (57/71) of ovarian endometriotic cysts diagnosed by laparoscopy were confirmed histologically with 43.6% in the left, 27.3% in the right; and 29.1% (16/55) in both sides of the ovary. In addition, 18.5% (10/54) of normal-appearing peritoneal biopsy were identified as endometriosis by pathological examination. Laparoscopy was confirmed to be in 100% diagnostic accordance with pathology for patients with endometriosis.
  
  
  CONCLUSIONS
  Our study showed asymmetrical distribution of pelvic endometriosis. Peritoneal lesions in black or from sacral ligament are more likely to be histologically confirmed, and microscopic lesions are not a rare phenomenon of endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: Jin-hua
authors.initials: JH
authors.lastname: Leng
authors.forename: Jing-he
authors.initials: JH
authors.lastname: Lang
authors.forename: Xue-ying
authors.initials: XY
authors.lastname: Zhao
authors.forename: Hua-jun
authors.initials: HJ
authors.lastname: Li
authors.forename: Li-na
authors.initials: LN
authors.lastname: Guo
authors.forename: Quan-cai
authors.initials: QC
authors.lastname: Cui
mesh_terms: D000328:Adult; D001706:Biopsy; D004715:Endometriosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D010053:Ovary / Q000473:pathology; D010388:Pelvis / Q000473:pathology; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014591:Uterine Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery