title: Management of skin ulcers in a patient with mycosis fungoides.
abstract: We present a patient with a cutaneous T-cell lymphoma/mycosis fungoides (CTCL/MF) followed for more than 10 years. After several different aggressive treatments to control progression of CTCL/MF, the patient developed several ulcerated tumors on the abdomen and limbs. Specific systemic antibiotic therapy failed to treat skin infection. While treating the stage III CTCL with polychemotherapy, we used an active colloidal hydrogel topically to manage wound healing and to treat and prevent potential sources of sepsis. After 11 weeks of treatment we observed complete cicatrization of ulcerated tumors. We reported on this case to describe the importance of a correct management of skin ulcers in immunosuppressed patients in order to avoid possible systemic spread of infection which represents the major cause of death in these patients.
authors.affiliation: Department of Dermatology, University La Sapienza, Rome, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Panasiti
authors.forename: Valeria
authors.initials: V
authors.lastname: Devirgiliis
authors.forename: Riccardo G
authors.initials: RG
authors.lastname: Borroni
authors.forename: Mariarita
authors.initials: M
authors.lastname: Rossi
authors.forename: Michela
authors.initials: M
authors.lastname: Curzio
authors.forename: Monica
authors.initials: M
authors.lastname: Mancini
authors.forename: Ugo
authors.initials: U
authors.lastname: Bottoni
authors.forename: Stefano
authors.initials: S
authors.lastname: Calvieri
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D020100:Hydrogels; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications* / Q000628:therapy; D012878:Skin Neoplasms / Q000150:complications* / Q000628:therapy; D012883:Skin Ulcer / Q000209:etiology / Q000628:therapy*
chemical_list: D020100:Hydrogels