[A study on outcome of surgical treatment for focal dystonia].
OBJECTIVE
To analysis the outcome of stereotactic nucleus lesioning for focal dystonia patients.


METHODS
Twenty-three focal dystonia patients were divided into 2 groups according to etiological factor. Stereotactic nucleus lesioning was performed for 10 primary dystonia patients of group A and 13 secondary patients of group B. The change of motor function was investigated and matched between 2 groups after 6 months follow-up.


RESULTS
Significant improvement of motor abilities was observed in patients of group A. The mean improvement of patients of group B was 43.8%. And the individual difference of improvement was obvious in patients of group B.


CONCLUSIONS
Stereotactic nucleus lesioning displays a satisfactory therapeutic effect for patients of writer's cramp. The efficacy of nucleus lesioning for secondary focal dystonia patients depends on the extensive of brain functional lesion. A structurally normal brain is not certainly a predictor of good response to surgical treatment.
Zhang
Yu-qing
YQ
Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China. yuqzhang@sohu.com
Li
Yong-jie
YJ
Zhang
Xiao-hua
XH
D000293:Adolescent; D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D002648:Child; D004421:Dystonia / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013238:Stereotaxic Techniques; D016896:Treatment Outcome