title: [Surgical diagnosis and treatment of Castleman's disease].
abstract: OBJECTIVE
  To investigate the clinical features and treatment of the surgical tumors associated with Castleman's disease.
  
  
  METHODS
  The clinical data of 20 patients with Castleman's disease, 6 males and 14 females, aged 39 (15-70), with the tumor size ranging from 2 cm x 3 cm to 10 cm x 9 cm, and with the tumor located in the mediastinal cavity (n = 6), retroperitoneal area (n = 2), abdominal cavity (n = 1), adrenal area (n = 1), neck and armpit (n = 2), and multi-centers (n = 2), were analyzed.
  
  
  RESULTS
  Nineteen of the 20 patients underwent surgical resection of the tumor or lymph node. All were diagnosed as Castleman's disease by pathological examination. Most of the tumor was benign. Three cases were diagnosed as with paraneoplastic pemphigus.
  
  
  CONCLUSIONS
  Surgical resection of the tumor is the first choice for treatment of Castleman's disease.
authors.affiliation: Department of Surgical Urology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Bing-bing
authors.initials: BB
authors.lastname: Shi
authors.forename: Han-zhong
authors.initials: HZ
authors.lastname: Li
authors.forename: Shi
authors.initials: S
authors.lastname: Rong
authors.forename: Yong-jun
authors.initials: YJ
authors.lastname: Zhao
authors.forename: Hua
authors.initials: H
authors.lastname: Fan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005871:Castleman Disease / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016896:Treatment Outcome