Synthesis of galactosaminyl D-chiro-inositols.
All six isomeric D-galactosaminopyranosyl-D-chiro-inositols have been prepared by glycosylation of appropriate penta-O-benzyl-D-chiro-inositols. The three requisite protected D-chiro-inositols were prepared by SmI2-promoted pinacol coupling of dialdehydes derived ultimately from L-arabinose.
Marnera
Georgia
G
Department of Chemistry, Michael Research Building, Tufts University, Medford, MA 02155, USA.
d'Alarcao
Marc
M
D005688:Galactosamine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D007294:Inositol / Q000138:chemical synthesis*; D007295:Inositol Phosphates / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry
C504571:D-chiro-inositol-galactosamine; D007295:Inositol Phosphates; D011134:Polysaccharides; C028039:inositol phosphate glycan; D007294:Inositol; D005688:Galactosamine