[Significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C].
BACKGROUND
To investigate the significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C.


METHODS
Totally 56,400 anti-HCV negative blood samples collected from Jan. 2000 to Dec. 2003 were tested for HCV RNA by RT-PCR, and the patients who received the HCV RNA negative blood were followed up.


RESULTS
The HCV RNA positive rate was 2.5 per thousand (146/56,000) and none of the patients followed up suffered from HCV infection.


CONCLUSIONS
HCV RNA screening for the anti-HCV negative blood samples is very effective and feasible for prevention of post-transfusion hepatitis C.
Zhang
Ying
Y
Department of Infectious Diseases, Heilongjiang Provincial Hospital, Harbin 150036, China.
Li
Jing
J
Liu
Yu-feng
YF
Zhao
Hong-wei
HW
Tian
Geng-shan
GS
D005240:Feasibility Studies; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008403:Mass Screening / Q000379:methods; D012367:RNA, Viral / Q000097:blood* / Q000235:genetics; D015203:Reproducibility of Results; D020133:Reverse Transcriptase Polymerase Chain Reaction; D065227:Transfusion Reaction
D012367:RNA, Viral