title: A 3D reconstruction algorithm for EIT using a handheld probe for breast cancer detection.
abstract: A 3D reconstruction algorithm for electrical impedance tomography is presented for determining the distribution of electrical properties inside the body, given electrical measurements made on the surface. A linearized reconstruction algorithm using planar electrode arrays in a handheld probe geometry developed by Mueller et al (1999 IEEE Trans. Biomed. Eng. 46 1379-86) has been refined and extended in this paper. This algorithm is based on linearizing the conductivity about a constant value. We have extended the distance below the electrodes at which a target can be imaged by using a combination of two regularization schemes and a weighted mesh. An appropriate combination of Tikhonov and NOSER regularization produces satisfactory static images of a 2 cm cube placed 2 cm below the array, and difference images of a 1 cm cube 4 cm away from the array. The weighted mesh allows use of fixed regularization parameters for all depths of the target.
authors.affiliation: Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180-3590, USA.
authors.forename: Tzu-Jen
authors.initials: TJ
authors.lastname: Kao
authors.forename: D
authors.initials: D
authors.lastname: Isaacson
authors.forename: J C
authors.initials: JC
authors.lastname: Newell
authors.forename: G J
authors.initials: GJ
authors.lastname: Saulnier
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation* / Q000379:methods*; D017097:Electric Impedance; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019047:Phantoms, Imaging; D010992:Plethysmography, Impedance / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014054:Tomography / Q000379:methods*; D014159:Transducers