[Surgical diagnosis and treatment of Castleman's disease].
OBJECTIVE
To investigate the clinical features and treatment of the surgical tumors associated with Castleman's disease.


METHODS
The clinical data of 20 patients with Castleman's disease, 6 males and 14 females, aged 39 (15-70), with the tumor size ranging from 2 cm x 3 cm to 10 cm x 9 cm, and with the tumor located in the mediastinal cavity (n = 6), retroperitoneal area (n = 2), abdominal cavity (n = 1), adrenal area (n = 1), neck and armpit (n = 2), and multi-centers (n = 2), were analyzed.


RESULTS
Nineteen of the 20 patients underwent surgical resection of the tumor or lymph node. All were diagnosed as Castleman's disease by pathological examination. Most of the tumor was benign. Three cases were diagnosed as with paraneoplastic pemphigus.


CONCLUSIONS
Surgical resection of the tumor is the first choice for treatment of Castleman's disease.
Shi
Bing-bing
BB
Department of Surgical Urology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
Li
Han-zhong
HZ
Rong
Shi
S
Zhao
Yong-jun
YJ
Fan
Hua
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D005871:Castleman Disease / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016896:Treatment Outcome