Unilateral diaphragm paralysis possibly due to cervical spine involvement in multiple myeloma.
OBJECTIVE
To describe a patient with unilateral diaphragmatic paralysis due to multiple myeloma (MM) involving the cervical spine and related structures.


METHODS
A 52-year-old female presented with dyspnea, low back and widespread bone pain. She was diagnosed as having MM with vertebral involvement and unilateral paralysis of the diaphragm. She received two cycles of a chemotherapeutic regimen consisting of vincristine-Adriamycin-dexamethasone. The bisphosphonate zoledronic acid was also initiated at the same time. During follow-up, the back pain disappeared and the complaint of dyspnea decreased, although the paralysis persisted.


CONCLUSIONS
As part of the differential diagnosis of bone and back pain, we draw attention to MMand the rare complication of diaphragmatic paralysis due to phrenic nerve involvement.
Kara
Murat
M
Department of Physical Medicine and Rehabilitation, Hacettepe University Medical School, Ankara, Turkey.
Isik
Metin
M
Ozcakar
Levent
L
Erol
Ozlem
O
Dogan
Serkan
S
Altundag
Kadri
K
Aksu
Salih
S
D002574:Cervical Vertebrae; D003964:Diaphragm; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D010243:Paralysis / Q000209:etiology*; D013125:Spinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013904:Thoracic Vertebrae