[Asthma or laryngeal amyloidosis? A report of a case and literature review].
The laryngeal amyloidosis is an uncommon disease accounting for 1% of all benign lesions of larynx. The commonest symptom is the dysphonia, sometimes accompanied by stridor, laryngeal globus sensation, dysphagia and, in rare occasions, cough, dyspnea and hemoptysis, specially when the tracheobronchial tree is also affected. This paper describes the case of a 30-year-old female patient, whose main symptoms were progressive dysphonia and dyspnea, admitted at allergy service to rule out asthma. The respiratory function tests showed obstruction in the medium and small caliber ways without reversibility with salbutamol. Biopsies of ventricular band, vocal cord and arytenoid stained with positive Congo red for amyloid tissue, established the laryngeal amyloidosis diagnosis. The complementary studies to rule out amyloid tissue in the remaining tracheobronchial tree were negative. Dyspnea had characteristics of laryngeal origin, caused by a pulmonary ventilation disorder provoked by the difficult arrival of air to alveoli, which caused the decreased partial pressure of oxygen and CO2.
Segura Méndez
Nora Hilda
NH
Médica adscrita al servicio de Alergia e Inmunología Clinica, Hospital de Especialidades Bernardo Sepúlveda, Centro Médico Nacional Siglo XXI, IMSS.
Barragán Estrada
María de la Luz
Mde L
Paredes Delgado
María de Lourdes
Mde L
Torres Salazar
Augusto Bernardo
AB
Betancourt Hernández
Lidia Angélica
LA
Canizales Cobos
Martín
M
Murillo Gómez
Erika
E
Martínez Hernández
Luis Enrique
LE
Mora Nieto
Alejandra
A
D000328:Adult; D000402:Airway Obstruction / Q000209:etiology; D000686:Amyloidosis / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D001249:Asthma / Q000175:diagnosis*; D002245:Carbon Dioxide / Q000097:blood; D003680:Deglutition Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D009784:Occupational Diseases / Q000175:diagnosis; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D013663:Teaching; D014832:Voice Disorders / Q000209:etiology
D002245:Carbon Dioxide; D010100:Oxygen