title: Primary Aspergillus and Fusarium keratitis in a Holstein cow.
abstract: A 5-year-old female Holstein cow was examined for ocular discharge, periorbital swelling, an area of full-thickness corneal cellular infiltrate, fibrin, hypopyon, diffuse corneal edema, and miosis. The patient was diagnosed with a corneal stromal abscess and secondary anterior uveitis. Histopathology, mycotic culture, and polymerase chain reaction positive for Aspergillus and Fusarium DNA confirmed the presence of fungal infection. Response to therapy was adequate, and follow-up with the patient 1 year after diagnosis revealed a focal area of corneal fibrosis.
authors.affiliation: Florida Veterinary Specialists, 3000 Busch Lake Blvd., Tampa, Florida 33614, USA. dogdoc2b@hotmail.com
authors.forename: Colleen R
authors.initials: CR
authors.lastname: Elligott
authors.forename: David A
authors.initials: DA
authors.lastname: Wilkie
authors.forename: Vanessa J
authors.initials: VJ
authors.lastname: Kuonen
authors.forename: I Dineli
authors.initials: ID
authors.lastname: Bras
authors.forename: Andrew
authors.initials: A
authors.lastname: Neihaus
mesh_terms: D000818:Animals; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004271:DNA, Fungal / Q000032:analysis; D005260:Female; D005670:Fusarium / Q000302:isolation & purification*; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D004271:DNA, Fungal