title: Anti Kell allo-antibody in a thalassaemic.
abstract: We describe a case of incidental detection of anti Kell antibody in a child with transfusion dependent thalassaemia. Kell antibody detection may be missed by routine indirect antiglobulin test (IAT) crossmatch procedure because of low prevalence of Kell antigen in the general population. A false negative result can be avoided by using sensitive cross matching techniques and screening cells representing antigens in homozygous state, against all clinically significant antibodies. A transfusion alert card describing the nature of antibody and future transfusion policy should be given to such allo-immunized patients.
authors.affiliation: Department of Transfusion Medicine and Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh. beenschor@yahoo.co.in
authors.forename: Beenu
authors.initials: B
authors.lastname: Thakral
authors.forename: Karan
authors.initials: K
authors.lastname: Saluja
authors.forename: Ratti Ram
authors.initials: RR
authors.lastname: Sharma
authors.forename: Neelam
authors.initials: N
authors.lastname: Marwaha
authors.forename: R K
authors.initials: RK
authors.lastname: Marwaha
mesh_terms: D000293:Adolescent; D001803:Blood Transfusion; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000097:blood*; D007626:Kell Blood-Group System / Q000276:immunology*; D013789:Thalassemia / Q000150:complications* / Q000276:immunology*
chemical_list: D007518:Isoantibodies; D007626:Kell Blood-Group System