[Adult-to-adult living donor liver transplantation for decompensated end-stage liver diseases].
OBJECTIVE
To summarize our clinical experience in adult-to-adult living donor liver transplantation (ALDLT).


METHODS
Clinical data of 12 patients with ALDLT performed in our center from September 2000 to June 2005 were analyzed, retrospectively.


RESULTS
Left lobe (segments II, III, IV, including the middle hepatic veins) transplantation was performed in 3 patients and right lobe (segments V, VI, VII, VIII, with or without the middle hepatic veins) transplantation was performed in 9 patients. Donors: There were no operative deaths. The median operative time was 6.20+/-1.40 hours and their blood loss ranged from 300 ml to 1200 ml. Postoperative complications included biliary fistula (1 donor) and wound fat liquefaction (1 donor). During a 6-12 months follow-up, no long-term complications were found. Recipients: The operating time ranged from 5 to 11 hours and their blood loss ranged from 800 to 7000 ml. Modified outflow reconstruction, microvascular reconstruction of the hepatic artery and duct-to-duct biliary reconstruction were done during the recipient operations. The median cold ischemia time was 1.90+/-0.50 hours. The median anhepatic phase of recipients was 1.63+/-0.43 hours. Graft/recipient weight ratio (GRWR) was (1.20+/-0.26)%. One recipient presented a postoperative complication of biliary fistula and another recipient died 1 month after the operation from serious infection. The other 11 recipients had long-term survivals.


CONCLUSIONS
ALDLT is an effective treatment for decompensated end-stage liver disease patients and is relatively safe for the donors.
Li
Xiang-cheng
XC
Liver Transplantation Center, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. doclixc@hotmail.com
Wang
Xue-hao
XH
Zhang
Feng
F
Xu
San-rong
SR
Cheng
Feng
F
Li
Guo-qiang
GQ
Wang
Ke
K
Qian
Xiao-feng
XF
Ma
Yue-Feng
YF
D000328:Adult; D005260:Female; D006527:Hepatolenticular Degeneration / Q000601:surgery*; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male