title: Fibrous hamartoma of infancy: an Italian multi-institutional experience.
abstract: BACKGROUND
  Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative.
  
  
  OBJECTIVE
  The clinical features and treatment results of 18 children with FH are described.
  
  
  RESULTS
  Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery.
  
  
  CONCLUSIONS
  The results did not reach statistical significance due to difficulties in collecting cases.
  
  
  CONCLUSIONS
  FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.
authors.affiliation: Division of Paediatric Surgery, Department of Paediatrics, University of Padua, Padua, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Carretto
authors.forename: Patrizia
authors.initials: P
authors.lastname: Dall'Igna
authors.forename: Rita
authors.initials: R
authors.lastname: Alaggio
authors.forename: Fortunato
authors.initials: F
authors.lastname: Siracusa
authors.forename: Claudio
authors.initials: C
authors.lastname: Granata
authors.forename: Andrea
authors.initials: A
authors.lastname: Ferrari
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cecchetto
mesh_terms: D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006222:Hamartoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007558:Italy; D008297:Male; D012871:Skin Diseases / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome