title: Early colon cancer detected by 18F-FDG PET.
abstract: Positron emission tomography (PET) is a noninvasive functional imaging modality that can disclose the presence of a malignant disease. It has recently been reported that PET may be useful to detect primary colorectal cancer (CRC). We present the case of a 47-yr-old man with early colon cancer detected by 18F-fluorodeoxyglucose (FDG) PET. The patient consulted us because of a positive fecal occult blood test and focal FDG uptake in the pelvic cavity detected at a physical check-up. After the usual work up, he was diagnosed as having a sigmoid polyp, 16 mm in diameter. Subsequently, colonoscopic polypectomy was carried out. The surgical specimen was histologically diagnosed as a well-differentiated adenocarcinoma, invading the submucosal layer with lymphatic invasion. Therefore, the involved portion of the sigmoid colon was laparoscopically resected. The FDG PET carried out 1 yr after the operation, showed no abnormal FDG uptake. PET can noninvasively detect an early colon cancer as small as in our patient, as well as other cancers in the whole body. Therefore, we consider it suitable as a screening examination.
authors.affiliation: Department of Coloproctological Surgery, Juntendo University, School of Medicine, Tokyo, Japan. kazusaka@med.juntendo.ac.jp
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Takahashi
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Yaginuma
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ishido
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsuoka
authors.forename: Shuichi
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tomiki
authors.forename: Toshiki
authors.initials: T
authors.lastname: Kamano
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D003111:Colonic Polyps / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D042241:Early Diagnosis; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18