title: Hemorrhage predisposing to cerebral infarction in children with moyamoya disease.
abstract: Two children with a new diagnosis of hemorrhagic type moyamoya disease experienced cerebral infarction after intraventricular hemorrhage. The patients developed ischemia 15 and 2 days after the initial diagnosis of hemorrhage. No provocative factor such as hypoperfusion was identified, but both patients exhibited signs of increased intracranial pressure on computed tomographic scan before infarction. Increased intracranial pressure in the setting of hemorrhage may be a risk factor for ischemic complications in patients with moyamoya disease. The optimal acute management of these patients requires further study.
authors.affiliation: Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Mubeen F
authors.initials: MF
authors.lastname: Rafay
authors.forename: Sabrina E
authors.initials: SE
authors.lastname: Smith
authors.forename: Peter
authors.initials: P
authors.lastname: Dirks
authors.forename: Derek
authors.initials: D
authors.lastname: Armstrong
authors.forename: Gabrielle A
authors.initials: GA
authors.lastname: deVeber
mesh_terms: D000208:Acute Disease; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D009072:Moyamoya Disease / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed