title: Endometrial polyp with sex cord-like pattern.
abstract: We report on an unusual endometrial polyp in a postmenopausal woman taking tamoxifen for 7 years after surgical resection of a breast carcinoma. A 63-year-old woman with endometrial thickening was submitted to hysteroscopy with biopsy, which revealed a polyp with a sex cord-like pattern. The hysterectomy specimen showed florid adenomyosis, and in the background, there were rare sex cord-like foci. Immunohistochemistry can be useful in differentiating sex cord-like elements from metastatic breast cancer to endometrium. This is, to our knowledge, the first observation in literature correlated to tamoxifen intake.
authors.affiliation: Department of Anatomic Pathology, Faculty of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil.
authors.forename: Maísa Momesso
authors.initials: MM
authors.lastname: De Quintal
authors.forename: Liliana Aparecida Lucci
authors.initials: LA
authors.lastname: De Angelo Andrade
mesh_terms: D000071443:12E7 Antigen; D015703:Antigens, CD / Q000032:analysis; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D015815:Cell Adhesion Molecules / Q000032:analysis; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011127:Polyps / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D013629:Tamoxifen / Q000009:adverse effects / Q000627:therapeutic use; D014746:Vimentin / Q000032:analysis
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; D018931:Antineoplastic Agents, Hormonal; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D014746:Vimentin; D013629:Tamoxifen