title: Dexmedetomidine as rescue drug during awake craniotomy for cortical motor mapping and tumor resection.
abstract: Dexmedetomidine, approved for providing sedation in the critical care environment, is also used during awake craniotomies to facilitate procedures such as cortical mapping. Herein, we describe the use of dexmedetomidine as a rescue drug during awake craniotomy avoiding conversion to general anesthesia, thus allowing completion of cortical mapping.
authors.affiliation: Department of Anesthesiology, University of Alabama School of Medicine, Birmingham, Alabama 35249-6810, USA. tamoore@uab.edu
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Moore
authors.forename: James M
authors.initials: JM
authors.lastname: Markert
authors.forename: Robert C
authors.initials: RC
authors.lastname: Knowlton
mesh_terms: D001931:Brain Mapping / Q000379:methods*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000601:surgery*; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology; D003399:Craniotomy / Q000379:methods*; D020927:Dexmedetomidine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D014851:Wakefulness / Q000502:physiology
chemical_list: D020927:Dexmedetomidine