title: New images evoke FAScinating questions.
abstract: Two recent papers in Science reported the X-ray structures of the large, organizationally distinct animal and fungal fatty acid synthases at 5 A. These new structural insights have unexpected implications for enzyme function for the other "iterative" and "assembly line" megasynthases.
authors.affiliation: Department of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.
authors.forename: Craig A
authors.initials: CA
authors.lastname: Townsend
authors.forename: Jason M
authors.initials: JM
authors.lastname: Crawford
authors.forename: Tsion
authors.initials: T
authors.lastname: Bililign
mesh_terms: D000818:Animals; D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D064429:Fatty Acid Synthases / Q000737:chemistry*; D005658:Fungi / Q000201:enzymology; D008958:Models, Molecular; D015394:Molecular Structure; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary
chemical_list: D064429:Fatty Acid Synthases