Progressive sclerodermatous skin changes in a child with phenylketonuria.
We report a child with phenylketonuria and unusually severe sclerodermatous skin changes. It is likely that prompt and aggressive therapy for these skin changes and phenylketonuria may have modified the clinical course.
Al-Mayouf
Sulaiman M
SM
Department of Pediatrics, King Faisal Specialist Hospital, Riyadh, Saudi Arabia. mayouf@kfshrc.edu.sa
Al-Owain
Mohammed A
MA
D002648:Child; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use; D010661:Phenylketonurias / Q000150:complications*; D011241:Prednisone / Q000627:therapeutic use; D012595:Scleroderma, Systemic / Q000188:drug therapy* / Q000209:etiology*
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone; D008727:Methotrexate