title: Aplasia cutis congenita of the scalp: is there a better treatment strategy?
abstract: BACKGROUND
  Aplasia cutis congenita (ACC) is a rare disease of unknown etiology, involving any site of the body. The scalp is the most frequent location, followed by the forearms, knees, both sides of the trunk, and neck, in decreasing order of frequency. Superficial lesions may heal spontaneously and seldom result in morbidity or mortality. However, in patients with large scalp and skull defects, there are risks of infection and bleeding. Conservative treatment has been described and advocated, but some authors have highlighted the disadvantages of this treatment modality. On the other hand, several authors claim that aggressive surgical treatment has an important role for large defects.
  
  
  METHODS
  In this paper, we report three newborns with ACC of the scalp, two large defects and a medium one, respectively, treated conservatively and surgically.
  
  
  CONCLUSIONS
  The management of ACC of the scalp is still controversial. Our series suggests that conservative treatment should be performed for initial management in newborns.
authors.affiliation: Division of Pediatric Neurosurgery, Ribeirão Preto School of Medicine, University of São Paulo, Campus Universitário, 14049-900 Ribeirão Preto, Brazil. rsoliveira30@yahoo.fr
authors.forename: Ricardo
authors.initials: R
authors.lastname: Santos de Oliveira
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Barros Jucá
authors.forename: Antônio
authors.initials: A
authors.lastname: Lopes Lins-Neto
authors.forename: Maria
authors.initials: M
authors.lastname: Aparecida do Carmo Rego
authors.forename: Jaime
authors.initials: J
authors.lastname: Farina
authors.forename: Helio Rubens
authors.initials: HR
authors.lastname: Machado
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics / Q000401:mortality; D016025:Bone Transplantation; D002675:Child, Preschool; D004200:Diseases in Twins / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D004476:Ectodermal Dysplasia / Q000175:diagnosis / Q000235:genetics / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D012535:Scalp / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D016038:Skin Transplantation; D013524:Surgical Flaps; D015996:Survival Rate; D014057:Tomography, X-Ray Computed