[Drug interactions of tacrolimus].
Allogeneic hematopoetic stem cell transplantations can be complicated by a graft-versus-host disease (GvHD), i.e., immunocompetent cells from the transplanted bone marrow act against solid organs of the recipient. A GvHD is treated with immunosuppressants. Consequently, further drugs are required, for example in order to prevent infections and result in in polymedication of those patients with a risk of drug interactions. In this case report, drug interactions between tacrolimus and concomitant therapy in a stem-cell-transplanted patient are discussed.
Sumner
Melanie E
ME
Klinische Pharmazie und Pharmakotherapie, Heinrich-Heine-Universität Düsseldorf.
Albers
Stefanie
S
Schmidt
Klaus G
KG
Laws
Hans Jürgen
HJ
Läer
Stephanie
S
D004347:Drug Interactions; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D033581:Stem Cell Transplantation; D016559:Tacrolimus / Q000009:adverse effects*
D007166:Immunosuppressive Agents; D016559:Tacrolimus