Unusual manifestation of posttransplant lymphoproliferative disorder in the esophagus.
Early manifestations of posttransplant lymphoproliferative disorders (PTLD) are mainly associated with a primary Epstein-Barr virus (EBV) infection. Rapid increases in peripheral blood EBV DNA load are supposed to reliably predict PTLD. We report a boy who 6 months after living-related kidney transplantation presented with an extranodal esophageal manifestation of PTLD. Despite a primary EBV infection with tonsillitis, the peripheral blood EBV DNA remained low, hiding the progression to PTLD.
Kranz
B
B
Clinic of Pediatric Nephrology, University of Duisburg-Essen, Essen, Germany. birgitta.kranz@uni-essen.de
Vester
U
U
Becker
J
J
Woltering
T
T
Wingen
A-M
AM
Paul
A
A
Hoyer
P F
PF
D000328:Adult; D002648:Child; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology*; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D011183:Postoperative Complications / Q000276:immunology