[Possibilities to use the aromatase inhibitors for the treatment of the uterine fibroids].
OBJECTIVE
Review of the contemporary knowledge about the aromatase P 450 in the uterine fibroid cells and about possibilities to use the aromatase inhibitors in the treatment of uterine fibroids.


METHODS
Review of the literature.


METHODS
Obstetrics and Gynecology Department, Regional Hospital Pardubice.


CONCLUSIONS
The aromatase P-450 in the uterine fibroid cells has a large effect on the autocrinne potentiation of growing this tumor. There is a very probable possibility to use the aromatase inhibitors for the treatment of the uterine fibroids.
Persín
J
J
Gynekologicko-porodnické oddelení Krajské nemocnice, Pardubice.
D001141:Aromatase / Q000378:metabolism / Q000502:physiology; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy* / Q000378:metabolism; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000378:metabolism
D047072:Aromatase Inhibitors; D001141:Aromatase