title: Neuropsychological test profiles in schizophrenia and non-psychotic depression.
abstract: OBJECTIVE
  The study examined to what degree schizophrenia is characterized by a neuropsychological (NP) test profile specific in shape and level compared with depression and normal functioning.
  
  
  METHODS
  Fifty-three patients with schizophrenia, 45 with non-psychotic depression, and 50 normals were assessed with a comprehensive NP test battery and clinical instruments. NP test scores were factor analyzed into seven composite scores.
  
  
  RESULTS
  Schizophrenia patients performed significantly below normals across all seven composite scores, whereas depression patients were impaired in two. Verbal memory was most impaired. Sixty-two percent of schizophrenia patients were moderately or severely impaired, the corresponding figure for depression was 28%. Impairment was moderately associated with IQ level and clinical symptom load in schizophrenia, but not in depression.
  
  
  CONCLUSIONS
  Schizophrenia is characterized by deficits across a wide range of NP functions. Thirty-eight percent of the patients are within normal limits. A mild and limited NP disturbance is apparent in depression.
authors.affiliation: Department of Psychology, University of Oslo, Oslo, Norway. b.r.rund@psykologi.uio.no
authors.forename: B R
authors.initials: BR
authors.lastname: Rund
authors.forename: K
authors.initials: K
authors.lastname: Sundet
authors.forename: A
authors.initials: A
authors.lastname: Asbjørnsen
authors.forename: J
authors.initials: J
authors.lastname: Egeland
authors.forename: N I
authors.initials: NI
authors.lastname: Landrø
authors.forename: A
authors.initials: A
authors.lastname: Lund
authors.forename: A
authors.initials: A
authors.lastname: Roness
authors.forename: K I
authors.initials: KI
authors.lastname: Stordal
authors.forename: K
authors.initials: K
authors.lastname: Hugdahl
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D003865:Major Depressive Disorder / Q000523:psychology*; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D015588:Observer Variation; D012559:Schizophrenia / Q000150:complications*; D012720:Severity of Illness Index