[One case report of anti-JK1 antibody undetected on plasma sample].
The sensitivity of the detection of irregular antibodies (DIA) is one of the fundamental bases of transfusion safety. Its implementation is specified in accordance with a very specific framework that allows the use of serum or plasma. The case reported here points out a failure to detect irregular antibodies in plasma sample. Thus a low intensity anti-JK1 antibody detected and identified in serum slipped through unnoticed in plasma. The difficulties to detect and identify this antibody, well-known as a deceptive and dangerous one, are being discussed in order to better assess the limitations of DIA.
Clavier
B
B
Service d'immunohématologie des receveurs et distribution, centre de transfusion sanguine des armées Jean-Julliard , 1, rue du Lieutenant-Raoul-Batany, BP 410, 92141 Clamart cedex, France. bmoclavier@cegetel.net
Hadef
R
R
Ait Mansour
C
C
Janus
G
G
Joussemet
M
M
D000369:Aged, 80 and over; D000740:Anemia / Q000097:blood / Q000276:immunology; D001323:Autoantibodies / Q000097:blood*; D001787:Blood Group Incompatibility; D001803:Blood Transfusion / Q000592:standards*; D002850:Chromatography, Gel; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity
D001323:Autoantibodies; D006454:Hemoglobins