Recurrent episodes of intractable laryngospasm during dissociative sedation with intramuscular ketamine.
We report 2 cases of dissociative sedation with intramuscular ketamine with recurrent episodes of laryngospasm that we were unable to ventilate with bag-mask ventilation, in 1 case leading to endotracheal intubation to protect the airway. Supplemental oxygen was given throughout the sedations, and ventilatory status was noninvasively monitored on a continuous basis, providing detailed and objective documentation of the patients' clinical status throughout the sedations. We were, therefore, able to rapidly assess and confirm apnea, laryngospasm, and airway dysfunction.
Cohen
Virginia Grace
VG
Department of Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Krauss
Baruch
B
D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D005151:Facial Injuries / Q000628:therapy; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007442:Intubation, Intratracheal; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects*; D007826:Laryngismus / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D012008:Recurrence; D016896:Treatment Outcome
D000778:Anesthetics, Dissociative; D007649:Ketamine