title: HIV type 2 demyelinating encephalomyelitis.
abstract: A human immunodeficiency virus (HIV) type 2 (HIV-2)-infected African patient developed inflammatory demyelinating lesions of the optic nerves, spinal cord, and brain, which coincided with a decreasing CD4 cell count and with active HIV-2 replication. This case provides evidence that HIV-2 is neurotropic, extends the range of known HIV-2-associated neurological complications, and confirms the overlap between the neurological complications of HIV type 1 and HIV-2 infection.
authors.affiliation: Fondation Adolphe de Rothschild, Service de Neurologie, Paris, France. amoulignier@fo-rothschild.fr
authors.forename: Antoine
authors.initials: A
authors.lastname: Moulignier
authors.forename: Caroline
authors.initials: C
authors.lastname: Lascoux
authors.forename: Anne
authors.initials: A
authors.lastname: Bourgarit
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D003711:Demyelinating Diseases / Q000209:etiology* / Q000821:virology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000821:virology*; D015498:HIV-2 / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents