title: Health-related issues in individuals with agenesis of the corpus callosum.
abstract: OBJECTIVE
  To explore and compare the prevalence and expression of specific health-related variables in a large survey sample of persons with agenesis of the corpus callosum (ACC) and their siblings.
  
  
  METHODS
  Caregiver surveys of individuals with ACC (n=189) and their siblings (n=189) provided data regarding diagnoses, physical features, neurological and sensory information, feeding, elimination and sleep concerns, and some behavioural features.
  
  
  RESULTS
  Compared with their siblings, individuals with ACC had more concurrent conditions and were more likely to have altered pain perception and sensitivity to touch. In addition, individuals with ACC had more sensory deficits and abnormalities as well as altered patterns of feeding/eating, elimination and sleep.
  
  
  CONCLUSIONS
  These data raise important questions for future research and suggest the need for increased vigilance by caregivers and health-care professionals of individuals with callosal disorders. Early detection and intervention may help prevent or ameliorate health problems in this population.
authors.affiliation: College of Education and Human Development, University of Maine, Orono, ME 04469-5749, USA. dona.doherty@umit.maine.edu
authors.forename: D
authors.initials: D
authors.lastname: Doherty
authors.forename: S
authors.initials: S
authors.lastname: Tu
authors.forename: K
authors.initials: K
authors.lastname: Schilmoeller
authors.forename: G
authors.initials: G
authors.lastname: Schilmoeller
mesh_terms: D000293:Adolescent; D000328:Adult; D061085:Agenesis of Corpus Callosum; D000374:Aggression; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000150:complications; D001068:Feeding and Eating Disorders / Q000150:complications; D006304:Health Status; D006306:Health Surveys; D006311:Hearing Disorders / Q000150:complications; D006801:Humans; D007223:Infant; D019964:Mood Disorders / Q000150:complications; D010146:Pain / Q000503:physiopathology; D016728:Self-Injurious Behavior / Q000150:complications; D012678:Sensation Disorders / Q000150:complications; D035781:Siblings; D012893:Sleep Wake Disorders / Q000150:complications; D014039:Toilet Training; D014110:Touch / Q000502:physiology; D014786:Vision Disorders / Q000150:complications