Antifreeze ingestion by dogs and rats: influence of stimulus concentration.
Ingestive responses of 50 rats and 4 gastric-cannulated dogs to ethylene glycol-based antifreeze (AF) were found to be inversely related to concentration. The antifreeze was never preferred to water. Do thirsty animals that encounter weak AF solutions drink them solely for their water content, water-related oral tactile sensations, or both, being inadvertently poisoned in the process?
Doty
Richard L
RL
Smell and Taste Center, University of Pennsylvania Medical Center, Philadelphia 19104, USA. doty@mail.med.upenn.edu
Dziewit
J Andrew
JA
Marshall
David A
DA
D000818:Animals; D004285:Dogs / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D005026:Ethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects / Q000506:poisoning; D051381:Rats / Q000502:physiology*; D013894:Thirst / Q000502:physiology*
D005026:Ethylene Glycols