The identification of three novel MICA alleles by sequence-based typing.
During a study of MICA frequency in a healthy population and a cohort of patients suffering with inflammatory bowel disease, three DNA samples produced unusual reactivity patterns using polymerase chain reaction sequence-specific primers (PCR-SSP). These samples were subsequently characterized by sequence-based typing (SBT). Here, we report the sequence of these three novel MICA alleles.
Quiroga
I
I
Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Sweeney
D
D
Sutton
P M
PM
Ahmad
T
T
Walton
R
R
Barnardo
M C N M
MC
Fuggle
S V
SV
D000483:Alleles; D001483:Base Sequence; D016022:Case-Control Studies; D015331:Cohort Studies; D004247:DNA / Q000235:genetics; D017931:DNA Primers; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012689:Sequence Homology, Nucleic Acid
D017931:DNA Primers; D015395:Histocompatibility Antigens Class I; C099187:MHC class I-related chain A; D004247:DNA