Promoter mutations of an essential gene for pollen development result in disease resistance in rice.
Disease resistance and sexual reproductive development are generally considered as separate biological processes, regulated by different sets of genes. Here we show that xa13, a recessive allele conferring disease resistance against bacterial blight, one of the most devastating rice diseases worldwide, plays a key role in both disease resistance and pollen development. The dominant allele, Xa13, is required for both bacterial growth and pollen development. Promoter mutations in Xa13 cause down-regulation of expression during host-pathogen interaction, resulting in the fully recessive xa13 that confers race-specific resistance. The recessive xa13 allele represents a new type of plant disease resistance.
Chu
Zhaohui
Z
National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
Yuan
Meng
M
Yao
Jialing
J
Ge
Xiaojia
X
Yuan
Bin
B
Xu
Caiguo
C
Li
Xianghua
X
Fu
Binying
B
Li
Zhikang
Z
Bennetzen
Jeffrey L
JL
Zhang
Qifa
Q
Wang
Shiping
S
D000483:Alleles; D005799:Genes, Dominant / Q000502:physiology; D020043:Genes, Essential / Q000502:physiology*; D005808:Genes, Recessive / Q000502:physiology; D009154:Mutation; D012275:Oryza / Q000235:genetics / Q000254:growth & development / Q000382:microbiology*; D010935:Plant Diseases / Q000235:genetics* / Q000382:microbiology; D030821:Plants, Genetically Modified; D011058:Pollen / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*; D011401:Promoter Regions, Genetic / Q000235:genetics