Müllerian anomalies, hearing loss, and connexin 26 mutations.
In a study of the possible inter-relationship among müllerian anomalies, hearing loss, and connexin 26 mutations, we evaluated all women in whom müllerian anomalies were diagnosed on hysterosalpingography during a 6-year period (n = 24/519). Audiometric testing revealed five (22.7%) with unrecognized sensorineural hearing loss; however, on genetic evaluation, none harbored a connexin 26 mutation.
Rabinson
Jacob
J
Department of Obstetrics, Barzilai Medical Center, Ben-Gurion University, Ashkelon, Israel.
Orvieto
Raoul
R
Shapira
Amnon
A
Brownstein
Zippora
Z
Meltzer
Simion
S
Tur-Kaspa
Ilan
I
D000072259:Connexin 26; D017630:Connexins / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology / Q000235:genetics; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics*; D006801:Humans; D009095:Mullerian Ducts / Q000002:abnormalities*; D015995:Prevalence; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors
D017630:Connexins; D000072259:Connexin 26