Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.
Between 1970 and 2003, seven cases of human dura mater-associated Creutzfeldt-Jakob disease (CJD) were identified in the UK. Furthermore, we identified a case of CJD in a porcine dura graft recipient. The mean incubation period of the human dura mater cases was 93 (range 45-177) months. The clinico-pathological features of the cases are described and compared with cases previously reported in the world literature.
Heath
C A
CA
National CJD Surveillance Unit, Bryan Matthews Building, Western General Hospital, Edinburgh EH4 2XU, UK.
Barker
R A
RA
Esmonde
T F G
TF
Harvey
P
P
Roberts
R
R
Trend
P
P
Head
M W
MW
Smith
C
C
Bell
J E
JE
Ironside
J W
JW
Will
R G
RG
Knight
R S G
RS
D000328:Adult; D000818:Animals; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000473:pathology* / Q000635:transmission*; D004388:Dura Mater / Q000473:pathology* / Q000637:transplantation*; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D011159:Population Surveillance; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000009:adverse effects*; D006113:United Kingdom / Q000453:epidemiology