Brain and optic nerve ischemia in malaria with immune disorders.
We report an unusual case of Plasmodium falciparum malaria in a European returning from tropical regions associating an anterior ischemic optic neuropathy and an asymptomatic centropontine myelinolysis. The transient antiphospholipid antibodies detected in the patient may have played a role in the ischemic process at the origin of this unusual clinical association.
Gallien
Sebastien
S
Infectious Diseases Department, Saint-Louis Hospital, 1, Avenue Claude Vellefaux, 75010 Paris, France. sebastien_gallien@yahoo.fr
Milea
Dan
D
Thiebaut
Marie-Marthe
MM
Bricaire
François
F
Le Hoang
Phuc
P
D017152:Antibodies, Antiphospholipid / Q000097:blood; D002545:Brain Ischemia / Q000209:etiology*; D005602:France; D006801:Humans; D016779:Malaria, Cerebral / Q000150:complications* / Q000276:immunology*; D016778:Malaria, Falciparum / Q000150:complications* / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000209:etiology*; D014195:Travel
D017152:Antibodies, Antiphospholipid