title: Development of soft-based double-stranded peptide chelators which selectively separate europium and lanthanum ions based on the hardness concept.
abstract: New double-stranded peptide chelators (1) conjugated Cat (2,3-dihydroxybenzoic acid) were synthesized and formed a molecular complex 1-Eu(3+) (or 1-Lu(3+)) with Eu(3+) and Lu(3+) but not La(3+). The double-stranded peptide chelator may prove to be useful tools for studying the selective separation of lanthanide ions.
authors.affiliation: Department of Analytical Chemistry of Medicines, Showa Pharmaceutical University,3-3165 Higashi-tamagawagakuen, Machida, Tokyo 194-8543, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Atuhiro
authors.initials: A
authors.lastname: Mizushima
authors.forename: Asako
authors.initials: A
authors.lastname: Sasuga
authors.forename: Makoto
authors.initials: M
authors.lastname: Watanabe
mesh_terms: D000465:Algorithms; D002614:Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry; D004583:Electrons; D005063:Europium / Q000302:isolation & purification*; D007202:Indicators and Reagents; D007811:Lanthanum / Q000302:isolation & purification*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D011487:Protein Conformation; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D002614:Chelating Agents; D007202:Indicators and Reagents; D010455:Peptides; D005063:Europium; D007811:Lanthanum