title: [Ethisorb/Ethisorb durapatch for the transnasal duraplasty procedure?].
abstract: BACKGROUND
  Defects of the dura in the rhinobasal area can be closed transnasally. Various procedures with autologous or alloplastic material can be chosen.
  
  
  METHODS
  From 2001 to 2004, we closed a rhinobasal dura defect with Ethisorb or Ethisorb durapatch in sandwich technique in 8 patients. After smoothing the bone edges, Ethisorb is applied under microscopic or endoscopic view endocranially, extradurally as "underlay" to seal and absorb the liquor pressure pillar. Additionally, another Ethisorb implant as "underlay" is applied extracranially from endonasally as "underlay", and sealed with a further layer of nasal concha mucosa with fibrin glue.
  
  
  RESULTS
  All patients were successfully treated with this technique. There were no evidences for persisting rhinoliquorrhoe after the period of wound healing. For hemostasia, a nasal package was applied for compression at the donor site of the inferior nasal concha. The former dura defect was at all times freely accessible in order to be able to recognize a possible new rhinoliquorrhoea early and to prevent a possible congestive secretion with superinfection.
  
  
  CONCLUSIONS
  The material of Ethisorb and Ethisorb durapatch is stiff and can be easily modelled, so it is an alternative as an alloplastic material for endonasal closure of defined substantial defects of the dura with rhinoliquorrhoe.
authors.affiliation: Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde und Poliklinik, Universitätsklinikum Freiburg, Killianstrasse 5, D-79106 Freiburg. arndt@hno.ukl.uni-freiburg.de
authors.forename: S
authors.initials: S
authors.lastname: Arndt
authors.forename: W
authors.initials: W
authors.lastname: Maier
authors.forename: A
authors.initials: A
authors.lastname: Aschendorff
authors.forename: T
authors.initials: T
authors.lastname: Klenzner
authors.forename: J
authors.initials: J
authors.lastname: Schipper
mesh_terms: D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000150:complications / Q000601:surgery; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000601:surgery*; D004388:Dura Mater / Q000293:injuries / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011091:Polyesters; D011100:Polyglycolic Acid; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery*; D019291:Skull Base / Q000293:injuries / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000601:surgery; D016896:Treatment Outcome
chemical_list: C460779:Ethisorb; D015718:Fibrin Tissue Adhesive; D011091:Polyesters; D011100:Polyglycolic Acid