title: Histopathology reporting of prostate needle biopsies. 2005 update.
abstract: This report reviews the diagnostic and prognostic importance of the pathologic findings in prostate needle biopsies. The morphological findings of the needle biopsy may be placed into one of the following five categories: prostate cancer, atypical small acinar proliferation, high-grade prostatic intraepithelial neoplasia, inflammation, and benign prostatic tissue. While the prime goal of the biopsy is to diagnose prostatic adenocarcinoma, once carcinoma is detected, further descriptive information regarding the type, amount of cancer, and grade forms the cornerstone for contemporary management of the patient and for assessment of the potential for local cure and the risk for distant metastasis. The information provided in the needle biopsy report regarding the attributes of carcinoma is used depending on the individual patient's medical condition and preference and on the treating physician's evaluation to determine whether any form of treatment is indicated and, if so, the type of therapy.
authors.affiliation: Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona), School of Medicine, United Hospitals, Via Conca 71, 60020 Torrette, Ancona, Italy. r.montironi@univpm.it
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.forename: Remigio
authors.initials: R
authors.lastname: Vela Navarrete
authors.forename: Antonio
authors.initials: A
authors.lastname: Lopez-Beltran
authors.forename: Roberta
authors.initials: R
authors.lastname: Mazzucchelli
authors.forename: Gregor
authors.initials: G
authors.lastname: Mikuz
authors.forename: Aldo V
authors.initials: AV
authors.lastname: Bono
mesh_terms: D000230:Adenocarcinoma / Q000145:classification / Q000473:pathology*; D001707:Biopsy, Needle / Q000639:trends*; D006801:Humans; D008297:Male; D011379:Prognosis; D011467:Prostate / Q000473:pathology*; D019048:Prostatic Intraepithelial Neoplasia / Q000145:classification / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000145:classification / Q000473:pathology*