Mechanical properties and antibacterial efficacy of chitosan films.
Chitin, chitosan and quaternary chitosan films were prepared, and the mechanical properties and the antibacterial activities of chitosan and quaternary chitosan films were evaluated. The tensile strength of chitin films was 30-40% lower than that of chitosan films, but the crystallinity of the former was much higher than those of the latter. A detailed analysis of the crystallinity and orientation of crystallites of chitosan films revealed that the cast film prepared with acetic acid provided a little lower crystallinity than the others. The antibacterial activities of quaternary chitosan films against Staphylococcus aureus and Escherichia coil were stronger than those of chitosan films. The antibacterial activities of neutralized chitosan films may be slightly inferior to those of un-neutralized chitosan films. The improvement in the antibacterial activity of chitosan films against E. coli was slightly inferior to that against S. aureus. This phenomenon was particularly observed on the neutralized chitosan films. Though the antibacterial activity of chitosan was slightly inferior to that of the organic antibacterial compounds, we emphasize that chitosan would be a useful and suitable material with regard to its effect on the environmental ecosystem.
Nakashima
Teruo
T
Institute of Resource Recycling, Kinki University, Faculty of Agriculture, 3327-204, Nakamachi, Nara 631-8505, Japan.
Matsuo
Masaru
M
Bin
Yuezhen
Y
Nakano
Yumiko
Y
Kobayashi
Tomonori
T
Komemushi
Sadao
S
Sakagami
Yoshikazu
Y
D019342:Acetic Acid; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology*; D001672:Biocompatible Materials / Q000032:analysis / Q000494:pharmacology; D020148:Butyric Acid; D002686:Chitin / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D048271:Chitosan / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D015169:Colony Count, Microbial; D003460:Crystallization; D017753:Ecosystem; D004783:Environmental Microbiology; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D005561:Formates; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011422:Propionates; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013718:Tensile Strength
D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D005561:Formates; D011422:Propionates; C030544:formic acid; D020148:Butyric Acid; D002686:Chitin; D048271:Chitosan; C029658:propionic acid; D019342:Acetic Acid