title: [Effect of intramural and subserous myomas on in vitro fertilization cycles and their perinatal results].
abstract: OBJECTIVE
  To evaluate the effect of intramural and subserous myomas in in vitro fertilization cycles, as well as its perinatal results.
  
  
  METHODS
  Cases and controls.
  
  
  METHODS
  All the IVF cycles between October 1999 and December 2004 were included. The variables of size and type of myomas, as well as variables of IVF cycles, implantation and pregnancy rates, and perinatal results were analyzed. We calculated the chi-square test to analyze the relationship between myomas and pregnancy. The t-Student test was used to establish the difference in the average between both groups regarding the studied variables. In the logistic regression analysis we controlled confusing variables.
  
  
  RESULTS
  We analyzed 431 cycles made in 364 patients divided into two groups: study cases (with myomas-65 cycles) and control cases (without myomas-366 cycles). Age was two years older in the study group (35.7 vs 33.5, p < 0.001). There was no difference in: duration, type of infertility, days of stimulation, gonadotrophin dose, total and mature follicles, and fertilization and implantation rates. We only observed a difference in the recovered oocytes (8.0 vs 9.7, p = 0.027). The pregnancy, abortion and live-born children rates were of 20.0 vs 23.2, 46.1 vs 29.4, and 46.1 vs 58.8%, respectively (study and control groups; p > 0.05). Logistic regression showed that myomas do not affect the possibility of getting pregnant.
  
  
  CONCLUSIONS
  Intramural and subserous myomas < 5 cm do not seem to have an effect in the IVF cycles nor in its perinatal results. In women with myomas < 5 cm that no dot distortion the uterine cavity it is questionable the usefulness of a myomectomy prior to IVF cycles.
authors.affiliation: Departamento de Reproducción Asistida, Instituto Nacional de Perinatología, Lomas Virreyes, México, DF.
authors.forename: Alberto
authors.initials: A
authors.lastname: Ballesteros Manzo
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Barros Delgadillo
authors.forename: Senia
authors.initials: S
authors.lastname: Ochoa Rueda
authors.forename: Sergio
authors.initials: S
authors.lastname: Villalobos Acosta
authors.forename: Gerardo
authors.initials: G
authors.lastname: Barroso Villa
authors.forename: Victor
authors.initials: V
authors.lastname: Sánchez Solís
authors.forename: Fernando
authors.initials: F
authors.lastname: Gaviño Gaviño
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D009214:Myoma; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D014594:Uterine Neoplasms / Q000473:pathology*