The role of molecular modelling in biomedical research.
The synergy between experimental and computational biology has greatly benefited both fields, providing invaluable information in many different areas of the life sciences. This minireview will focus on one specific aspect of computational biology, molecular modelling, and describe a few examples highlighting the effectiveness of protein structural analysis and modelling in providing relevant information about systems of biomedical interest.
Tramontano
Anna
A
Istituto Pasteur--Fondazione Cenci Bolognetti and Department of Biochemical Sciences Rossi Fanelli, University of Rome, La Sapienza, P.le Aldo Moro, 5, Rome 00185, Italy. Anna.Tramontano@uniroma1.it
D000911:Antibodies, Monoclonal / Q000737:chemistry; D016174:Hepacivirus / Q000737:chemistry; D020738:Leptin / Q000737:chemistry; D008958:Models, Molecular; D011487:Protein Conformation; D012106:Research; D014759:Viral Envelope Proteins / Q000737:chemistry
D000911:Antibodies, Monoclonal; D020738:Leptin; D014759:Viral Envelope Proteins