title: Seizure heralding functional recovery in a patient with apallic syndrome: A case report with retrospective-prospective observation.
abstract: BACKGROUND
  It has been suggested that there exists a close relationship between seizure discharges and functional recovery from brain injury, and that paroxysmal bombardment in late seizures may herald functional recovery or may "kick-start" recovery.
  
  
  METHODS
  We report the case of a 52-year-old patient who, following a subarachnoid hemorrhage and multiple surgeries, experienced discernible apallic syndrome of long duration. His hospitalization is well documented. The patient underwent protracted, intense rehabilitation, but he remained in this prolonged state of loss of consciousness and behavioral passivity until he experienced a series of periodic seizures. Widespread improvement in his cognitive and functional abilities coincided closely with the seizure activity. The literature on this topic is reviewed.
  
  
  CONCLUSIONS
  This case confirms the close relationship between seizure discharges and functional recovery reported in preclinical literature.
authors.affiliation: Department of Behavioral Medicine, College of Medicine and Health Science, Sultan Qaboos University, Muscat, Oman. jimbo@omantel.net.om
authors.forename: Samir
authors.initials: S
authors.lastname: Al-Adawi
authors.forename: David T
authors.initials: DT
authors.lastname: Burke
authors.forename: Sara E
authors.initials: SE
authors.lastname: Mastronardi
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012640:Seizures / Q000503:physiopathology*; D013345:Subarachnoid Hemorrhage / Q000150:complications*; D014474:Unconsciousness / Q000209:etiology / Q000503:physiopathology*