Toxoplasma: guess who's coming to dinner.
In this issue of Cell, Coppens and coworkers (Coppens et al., 2006) describe how Toxoplasma gondii, an obligate intracellular parasite, feeds on the host. Coppens et al. provide evidence that the parasite takes host cell endosomes and lysosomes hostage by sequestering them where the parasite resides, within invaginations of the parasitophorous vacuole.
Gruenberg
Jean
J
Department of Biochemistry, University of Geneva, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
van der Goot
F Gisou
FG
D000818:Animals; D000953:Antigens, Protozoan / Q000378:metabolism; D011992:Endosomes / Q000378:metabolism; D006790:Host-Parasite Interactions; D008247:Lysosomes / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism; D015800:Protozoan Proteins / Q000378:metabolism; D014122:Toxoplasma / Q000166:cytology / Q000502:physiology*
D000953:Antigens, Protozoan; C112573:GRA7 protein, Toxoplasma gondii; D015800:Protozoan Proteins