Alkaloids from Toddalia aculeata.
Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH(2)Cl(2):methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. (1)H-(1)H COSY, (1)H-(13)C COSY, and HMBC.
Jain
Subhash C
SC
Department of Chemistry, University of Delhi, Delhi 110 007, India. jainsc48@hotmail.com
Pandey
Mukesh K
MK
Upadhyay
Ravi K
RK
Kumar
Rohtash
R
Hundal
Geeta
G
Hundal
Maninder S
MS
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry; D008968:Molecular Conformation; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D015363:Quinolones / Q000737:chemistry* / Q000302:isolation & purification; D027821:Rutaceae / Q000737:chemistry*
C512953:3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one; D000470:Alkaloids; C512952:N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one; D015363:Quinolones