Cutaneous neuroendocrine adenoma: an uncommon neoplasm.
BACKGROUND
Cutaneous neuroendocrine neoplasms are typically malignant. Benign cutaneous neuroendocrine tumors are uncommon.


METHODS
We report the case of a 32-year-old female who presented with a granular mass in the right external auditory canal.


RESULTS
Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation. While cytologic atypia and mitotic activity were not evident, pagetoid spread was observed. Immunohistochemistry was indicative of neuroendocrine origin.


CONCLUSIONS
This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.
Mahalingam
M
M
UMass Memorial Medical Center, Memorial Campus, Worcester, MA 01605, USA. mahalinm@ummhc.org
Kveaton
J F
JF
Bhawan
J
J
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D004424:Ear Canal; D004428:Ear Neoplasms / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018358:Neuroendocrine Tumors / Q000175:diagnosis* / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis*
D014408:Biomarkers, Tumor