title: Idiopathic infantile arterial calcification: clinical presentation, therapy and long-term follow-up.
abstract: Idiopathic infantile arterial calcification (IIAC) is a rare disease characterised by extensive depositions of hydroxyapatite in the internal elastic lamina of medium-sized and large arteries, frequently accompanied by periarticular calcifications. We report on three patients with various presenting signs and symptoms. Diagnostic imaging techniques and therapy with bisphosphonates will be discussed. For the first time long-term follow-up of up to 25 years will be reported.
authors.affiliation: Department of Paediatrics, Erasmus Medical Centre, Sophia Children's Hospital, Dr Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands. i.vandersluis@erasmusmc.nl
authors.forename: Inge M
authors.initials: IM
authors.lastname: van der Sluis
authors.forename: Annemieke M
authors.initials: AM
authors.lastname: Boot
authors.forename: Meike
authors.initials: M
authors.lastname: Vernooij
authors.forename: Morteza
authors.initials: M
authors.lastname: Meradji
authors.forename: André A
authors.initials: AA
authors.lastname: Kroon
mesh_terms: D001157:Arterial Occlusive Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D002114:Calcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography