MR imaging and prognosis of hypoxic-ischemic leukoencephalopathy.
OBJECTIVE
To correlate prognosis of hypoxic-ischemic white-matter injury with magnetic resonance imaging (MRI).


METHODS
In a retrospective review at an urban medical center, three adult and three pediatric patients with predominant white-matter involvement caused by hypoxic- ischemic injury were evaluated over a 15-month period.


RESULTS
Five patients with MRI-defined hypoxic-ischemic leukoencephalopathy had a favorable outcome, and one with associated diffusion-weighted abnormality of deep gray structures died.


CONCLUSIONS
The prognosis of hypoxic-ischemic leukoencephalopathy is more favorable than previously reported, and diffusion-weighted imaging abnormality of deep gray structures was associated with a poor outcome.
Finelli
Pasquale F
PF
Department of Neurology, Hartford Hospital, CT 06102-5037, USA. Pfinell@harthosp.org
DiMario
Francis J
FJ
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015140:Dementia, Vascular / Q000150:complications* / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000473:pathology*; D008297:Male; D011379:Prognosis