Deep-seated resistance in relapsed paratyphoid fever.
We describe a case of relapsed paratyphoid fever in which the isolate had reduced susceptibility to ciprofloxacin due to a rare mutation within the gyrA gene. 18fluorodeoxyglucose positron emission tomography scanning identified deep-seated infection including unsuspected aortitis and highlights the utility of novel imaging techniques to improve our understanding and treatment of this disease.
Cooke
Graham S
GS
Department of Infectious Diseases, Hammersmith Hospital, London, United Kingdom. graham.cooke@st-mary's.nhs.uk
Cooke
Fiona J
FJ
Stone
Madeline
M
Turner
Keith
K
Al-Nahhas
Adil
A
Win
Zarni
Z
Wain
John
J
Rogers
Thomas R
TR
Friedland
Jon S
JS
Bamford
Kathleen B
KB
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008875:Middle Aged; D010284:Paratyphoid Fever / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D012008:Recurrence; D012482:Salmonella paratyphi A / Q000187:drug effects*
D000900:Anti-Bacterial Agents