title: [Influence factors of adjacent segment degeneration after instrumented lumbar fusion].
abstract: OBJECTIVE
  To investigate the influence factors of adjacent segment degeneration (ASD) after instrumented lumbar fusion.
  
  
  METHODS
  Thirty-three patients who had undergone an instrumented lumbar fusion from March 1998 to May 2002 were reviewed. The incidence, age, position, radiographic characteristics and clinical manifestations of ASD were studied. Then the relations between "floating fusion" and ASD were compared, the range of fusion and ASD and investigated the incidences of different adjacent segments.
  
  
  RESULTS
  The mean follow-up period for the patients was 4 years and 7 months (24 - 82 months). Adjacent segment degeneration mainly occurred in patients older than 60. Ten patients (10%) were found to have radiographic characteristics of ASD. Nine of the ten patients had ASD at cranial segments. Using "floating fusion" or not did not show difference in the risk of ASD. There was a trend of more ASDs after long-segment fusion than short-segment fusion. As an adjacent segment, L(2)/L(3) had a high risk of ASD, while L(5)/S(1) had a much lower risk.
  
  
  CONCLUSIONS
  The cranial segment has a higher degeneration risk than the caudal segment. If L(2)/L(3) has degenerative appearance and has chance to be the adjacent segment, we'd better fuse it. If there is no evidence of obvious degeneration, L(5)/S(1) should not be fused. During instrumented lumbar fusion, long-segment fusion should be avoided if possible.
authors.affiliation: Department of Orthopedics, Beijing University First Hospital, Beijing 100034, China.
authors.forename: Chun-de
authors.initials: CD
authors.lastname: Li
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Yu
authors.forename: Xian-yi
authors.initials: XY
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000209:etiology*; D013123:Spinal Fusion / Q000009:adverse effects* / Q000379:methods