title: Clinical impact of oral health indexes in dental extraction of hemophilic patients.
abstract: OBJECTIVE
  Periodontal disease in patients with hemorrhagic disorders may lead to severe bleeding during dental treatment. This study evaluated the clinical impact of oral health indexes in hemophilic patients undergoing tooth extraction.
  
  
  METHODS
  Thirty-one hemophilic patients underwent teeth extractions using autologous fibrin glue and an oral antifibrinolytic drug (epsilon-aminocaproic acid). Oral health indexes (plaque, PI; gingival, GI; and decay-missing-filling-teeth, DMFT index) were evaluated before tooth extraction.
  
  
  RESULTS
  Postsurgical bleeding episodes were observed in 6 hemophilic patients (1 severe, 3 moderate, and 2 mild type). The PI and GI index in the bleeding group were 1.8 and 1.7, respectively, and 1.8 for both of the non-bleeding groups (PI, P = .8; GI, P = .56). The global DMFT index was 18 in the bleeding group and 19.6 in the non-bleeding group (P = .67).
  
  
  CONCLUSIONS
  The status of oral health did not interfere with bleeding caused by dental extraction of hemophilic patients.
authors.affiliation: Dental Ambulatory, Hematology and Blood Transfusion Center/Hemocentro, State University of Campinas, São Paulo, Brazil. elvira@unicamp.br
authors.forename: Maria Elvira P
authors.initials: ME
authors.lastname: Correa
authors.forename: Joyce M
authors.initials: JM
authors.lastname: Annicchino-Bizzacchi
authors.forename: Jacks
authors.initials: J
authors.lastname: Jorge
authors.forename: Oslei
authors.initials: O
authors.lastname: Paes de Almeida
authors.forename: Margareth C
authors.initials: MC
authors.lastname: Ozelo
authors.forename: Francisco José P
authors.initials: FJ
authors.lastname: Aranha
authors.forename: Maria
authors.initials: M
authors.lastname: Lourdes Barjas-Castro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015119:Aminocaproic Acid / Q000627:therapeutic use; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D004245:DMF Index; D017742:Dental Care for Chronically Ill; D003774:Dental Plaque Index; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D005884:Gingival Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D009909:Oral Health; D010512:Periodontal Index; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D011237:Predictive Value of Tests; D014081:Tooth Extraction / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D000933:Antifibrinolytic Agents; D015718:Fibrin Tissue Adhesive; D015119:Aminocaproic Acid