title: Cognitive-behavioural therapy for substance use disorders in people with psychotic disorders: Randomised controlled trial.
abstract: BACKGROUND
  Few randomised controlled trials have been aimed specifically at substance use reduction among people with psychotic disorders.
  
  
  OBJECTIVE
  To investigate whether a 10-session intervention consisting of motivational interviewing and cognitive-behavioural therapy (CBT) was more efficacious than routine treatment in reducing substance use and improving symptomatology and general functioning.
  
  
  METHODS
  A community sample of people with a psychotic disorder and who reported hazardous alcohol, cannabis and/or amphetamine use during the preceding month was recruited. Participants were randomly allocated to motivational interviewing/CBT (n = 65) or treatment as usual (n = 65), and were assessed on multiple outcomes at baseline, 15 weeks, 6 months and 12 months.
  
  
  RESULTS
  There was a short-term improvement in depression and a similar trend with regard to cannabis use among participants who received the motivational interviewing/CBT intervention, together with effects on general functioning at 12 months. There was no differential benefit of the intervention on substance use at 12 months, except for a potentially clinically important effect on amphetamine use.
  
  
  CONCLUSIONS
  The motivational interviewing/CBT intervention was associated with modest improvements.
authors.affiliation: Centre for Mental Health Studies, University of Newcastle, University Drive, Callaghan, New South Wales 2308, Australia. amanda.baker@newcastle.edu.au
authors.forename: Amanda
authors.initials: A
authors.lastname: Baker
authors.forename: Sandra
authors.initials: S
authors.lastname: Bucci
authors.forename: Terry J
authors.initials: TJ
authors.lastname: Lewin
authors.forename: Frances
authors.initials: F
authors.lastname: Kay-Lambkin
authors.forename: Paul M
authors.initials: PM
authors.lastname: Constable
authors.forename: Vaughan J
authors.initials: VJ
authors.lastname: Carr
mesh_terms: D000293:Adolescent; D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009517:New South Wales; D011618:Psychotic Disorders / Q000150:complications / Q000628:therapy*; D019966:Substance-Related Disorders / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome