Cutaneous Crohn's disease mimicking Melkersson-Rosenthal syndrome: treatment with methotrexate.
A woman with a 5-year history of unilateral orofacial granulomatosis required repeated evaluations (including sequential colonoscopies) to establish the diagnosis of cutaneous Crohn's disease, a condition that proved responsive to low doses of oral methotrexate administered weekly. To our knowledge this is the first report describing the use of methotrexate for treatment of orofacial granulomatosis caused by underlying Crohn's disease.
Tonkovic-Capin
V
V
Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA. viseslav@mcw.edu
Galbraith
S S
SS
Rogers
R S
RS
Binion
D G
DG
Yancey
K B
KB
D000328:Adult; D003424:Crohn Disease / Q000175:diagnosis* / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005145:Face; D005260:Female; D006099:Granuloma / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis; D008727:Methotrexate / Q000627:therapeutic use*
D003879:Dermatologic Agents; D008727:Methotrexate