title: Cine delayed-enhancement MR imaging of the heart: initial experience.
abstract: This study was performed by using an institutional review board-approved protocol, with waived informed consent and HIPAA compliance. The purpose of this study was to preliminarily evaluate a cine delayed-enhancement (DE) pulse sequence for depiction of wall motion and myocardial scar extent during a single acquisition. The technique is based on inversion-recovery single-shot balanced steady-state free precession magnetic resonance imaging. Cine DE images were acquired in 26 patients (18 men, eight women; age range, 25-84 years; mean age, 61 years+/-13 [standard deviation]). Image contrast was consistent throughout each series. Overall (ie, with both readers' scores averaged), the cine DE imaging-depicted wall motion was scored correctly in 71% of myocardial segments. Scar extent was scored correctly in 76% of segments; in no patient was scarring missed. Cine DE imaging is a promising technique for simultaneous visualization of wall motion and myocardial scar extent.
authors.affiliation: Section of Cardiovascular Imaging, Division of Radiology, and Department of Biostatistics and Epidemiology, the Cleveland Clinic Foundation, 9500 Euclid Ave, Desk HB6, Cleveland, OH 44195, USA. setserr@ccf.org
authors.forename: Randolph M
authors.initials: RM
authors.lastname: Setser
authors.forename: Jae K
authors.initials: JK
authors.lastname: Kim
authors.forename: Yiu Cho
authors.initials: YC
authors.lastname: Chung
authors.forename: Kevin
authors.initials: K
authors.lastname: Chen
authors.forename: Arthur E
authors.initials: AE
authors.lastname: Stillman
authors.forename: Ralf
authors.initials: R
authors.lastname: Loeffler
authors.forename: Orlando P
authors.initials: OP
authors.lastname: Simonetti
authors.forename: Joan A
authors.initials: JA
authors.lastname: Weaver
authors.forename: Michael L
authors.initials: ML
authors.lastname: Lieber
authors.forename: Richard D
authors.initials: RD
authors.lastname: White
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002921:Cicatrix; D003287:Contrast Media; D004562:Electrocardiography; D005260:Female; D019786:Gadolinium DTPA; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000175:diagnosis*; D014022:Tissue Survival / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA