title: Ginsenoside Rg8, a new dammarane-type triterpenoid saponin from roots of Panax quinquefolium.
abstract: A new dammarane-type triterpenoid saponin, ginsenoside Rg(8) (1), was isolated from the roots of Panax quinquefolium, along with five known saponins, (20E)-ginsenoside F(4) (2), ginsenosides Rh(1) (3), Rg(2) (4), F(1) (5), and (20R)-ginsenoside Rh(1) (6). The structure of ginsenoside Rg(8) (1) was determined to be (3beta,6alpha,12beta,20E)-24,25-epoxy-3,12,23-trihydroxydammar-20(22)-en-6-O-alpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranoside by various spectroscopic analyses. Among the known saponins, (20E)-ginsenoside F(4) (2) and ginsenoside F(1) (5) were first reported from the title plant.
authors.affiliation: School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: Deqiang
authors.initials: D
authors.lastname: Dou
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Na
authors.initials: N
authors.lastname: Guo
authors.forename: Rui
authors.initials: R
authors.lastname: Fu
authors.forename: Yuping
authors.initials: Y
authors.lastname: Pei
authors.forename: Kazuo
authors.initials: K
authors.lastname: Koike
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Nikaido
mesh_terms: D036145:Ginsenosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D005894:Panax / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D036145:Ginsenosides; D012503:Saponins; D014315:Triterpenes; C035054:ginsenoside Rg1