title: Extranodal conjunctival Hodgkin's-like lymphoma in a cat.
abstract: A seven-year-old female spayed Domestic Short-haired cat was brought for examination following a four-month history of conjunctivitis in the right eye. The superior palpebral conjunctiva was diffusely swollen and firm, displacing the right globe ventrally and preventing full closure of the eyelids. The right popliteal lymph node was enlarged as were several other peripheral lymph nodes. An incisional biopsy of the conjunctival swelling revealed a lymphoid neoplasm, the cellular make up of which suggested features of feline Hodgkin's-like lymphoma. Although the neoplasm was poorly responsive to standard chemotherapeutic protocols for lymphoma, radiation therapy rapidly reduced its size. Three years following the initial diagnosis, there has been no recurrence of the conjunctival neoplasm. To the authors' knowledge, there are no previous reports of extranodal or adnexal (conjunctiva, eyelid, orbit) Hodgkin's-like lymphoma in the veterinary literature.
authors.affiliation: The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, United Kingdom. eholt@rvc.ac.uk
authors.forename: Elaine
authors.initials: E
authors.lastname: Holt
authors.forename: Michael H
authors.initials: MH
authors.lastname: Goldschmidt
authors.forename: Katherine
authors.initials: K
authors.lastname: Skorupski
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D002415:Cats; D003230:Conjunctival Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D003937:Diagnosis, Differential; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D016896:Treatment Outcome