title: [Utility of inhaled nitric oxide in patient with acute respiratory distress syndrome and un-operated Fallot's tetralogy].
abstract: Utility of inhaled nitric oxide in the treatment of acute respiratory distress syndrome (ARDS) with pulmonary hypertension (PHT) is controversial and there are few studies in the literature that evaluate its effects during prolonged administration. We analyze the case of a 45 day old male patient with un-operated Fallot's tetralogy who developed ARDS and PHT with non-cardiac cause, that required prolonged mechanical ventilation (30 days) and administration of inhaled nitric oxide (INO). Before the INO, the oxygenation index was 19, and at a few minutes of its application it decreased to 15. The patient developed a dependence on INO, tolerating its gradual weaning. Administration could be interrupted at 27 days on onset. We did not observe toxic effects during the administration of INO.
authors.affiliation: Unidad de Cuidados Intensivos Pediátricos y Neonatales, Complejo Hospitalario de Jaén, España. fjaladosarbol@supercable.es
authors.forename: F J
authors.initials: FJ
authors.lastname: Alados-Arboledas
authors.forename: J F
authors.initials: JF
authors.lastname: Expósito-Montes
authors.forename: F
authors.initials: F
authors.lastname: González-Rivera
authors.forename: C
authors.initials: C
authors.lastname: Santiago-Gutiérrez
authors.forename: L
authors.initials: L
authors.lastname: Millán-Miralles
authors.forename: J
authors.initials: J
authors.lastname: de la Cruz-Moreno
mesh_terms: D000280:Administration, Inhalation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007223:Infant; D008297:Male; D009569:Nitric Oxide / Q000008:administration & dosage*; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000150:complications* / Q000628:therapy*; D013771:Tetralogy of Fallot / Q000150:complications*
chemical_list: D009569:Nitric Oxide