Multifocal lymphangioendotheliomatosis with thrombocytopenia.
Multifocal lymphangioendotheliomatosis with thrombocytopenia is an extremely rare disease. This condition manifests as diffuse congenital vascular lesions in the skin and gastrointestinal tract leading to severe gastrointestinal bleeding and thrombocytopenia. Histopathologic and immunohistochemical studies of vascular lesions demonstrate a lymphatic endothelial cell origin. Treatment often is not satisfactory. We herein describe a 4-week-old infant with this uncommon clinicopathologic entity.
Yeung
Jensen
J
Department of Dermatology, University of Toronto, Canada.
Somers
Gino
G
Viero
Sandra
S
Pope
Elena
E
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D041981:Gastrointestinal Tract / Q000098:blood supply*; D006390:Hemangioendothelioma / Q000150:complications* / Q000151:congenital / Q000188:drug therapy / Q000473:pathology*; D006396:Hematemesis / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007231:Infant, Newborn; D008202:Lymphangioma / Q000150:complications* / Q000151:congenital / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D013194:Staining and Labeling; D013921:Thrombocytopenia / Q000209:etiology*; D014750:Vincristine / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D014750:Vincristine