title: Acquired von Willebrand syndrome in a patient with Ewing sarcoma.
abstract: Acquired von Willebrand syndrome is a rare bleeding disorder with clinical and laboratory features closely resembling to hereditary von Willebrand disease. The syndrome may accompany various conditions, including malignant disorders, most often with Wilms tumor and adrenal cell carcinoma. In this report, the authors present a patient with AvWS in association with Ewing sarcoma for the first time in the literature. The abnormal bleeding tendency was successfully treated with fresh frozen plasma and did not recur after the first two courses of chemotherapy with clinical improvement.
authors.affiliation: Department of Paediatric Oncology, Ondokuz Mayis University, Medical Faculty, Samsun, Turkey. ellimurat@yahoo.com
authors.forename: Murat
authors.initials: M
authors.lastname: Elli
authors.forename: Faruk Guclu
authors.initials: FG
authors.lastname: Pinarli
authors.forename: Ayhan
authors.initials: A
authors.lastname: Dagdemir
authors.forename: Nevzat
authors.initials: N
authors.lastname: Dabak
authors.forename: Tunc
authors.initials: T
authors.lastname: Fisgin
authors.forename: Mustafa Bekir
authors.initials: MB
authors.lastname: Selcuk
authors.forename: Sevinc
authors.initials: S
authors.lastname: Sultansuyu
authors.forename: Sabri
authors.initials: S
authors.lastname: Acar
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006470:Hemorrhage / Q000628:therapy; D006801:Humans; D008297:Male; D010949:Plasma; D012512:Sarcoma, Ewing / Q000150:complications* / Q000175:diagnosis; D014842:von Willebrand Diseases / Q000209:etiology*