Mecasermin Tercica.
Tercica, under license from Genentech, has developed and launched mecasermin, recombinant human insulin-like growth factor-1 (rhIGF-1), for the treatment of growth failure in children with primary IGF deficiency or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH.
Norman
Peter
P
Norman Consulting, 18 Pink Lane, Burnham, Bucks, UK. peter.norman2@btinternet.com
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002986:Clinical Trials as Topic; D003920:Diabetes Mellitus / Q000188:drug therapy; D006128:Growth / Q000187:drug effects; D006130:Growth Disorders / Q000188:drug therapy*; D013006:Growth Hormone / Q000172:deficiency; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000009:adverse effects / Q000138:chemical synthesis / Q000378:metabolism / Q000627:therapeutic use*; D013329:Structure-Activity Relationship
D036341:Intercellular Signaling Peptides and Proteins; C065700:myotrophin; D013006:Growth Hormone