title: Unique case of pulmonary bronchial gland type tumor with broad spectrum of cell differentiation from the terminal duct-acinar unit to excretory duct.
abstract: In the lung, acinic cell carcinoma (ACC) is a rare form of tumor. Reported herein is a unique bronchial gland-type tumor diagnosed as well-differentiated ACC that developed in the B9 bronchus of the left lung. Various immunohistochemical and histochemical staining partly satisfied the diagnosis of ACC. Moreover, this tumor contained various sizes of mucous cysts lined by columnar mucous cells, which produced abundant mucin positive for Alcian blue, which is usually present in mucoepidermoid carcinoma. Therefore, the present case is a unique tumor having a broad spectrum of cell differentiation from the terminal duct--acinar unit to the striated duct and excretory duct. This is the first case of unique bronchial gland-type tumor with mixed histological features of ACC and mucoepidermoid carcinoma.
authors.affiliation: Department of Tumor Pathology, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Gunma, Japan.
authors.forename: Gehan
authors.initials: G
authors.lastname: Gamal
authors.forename: Toshiteru
authors.initials: T
authors.lastname: Nagashima
authors.forename: Osamu
authors.initials: O
authors.lastname: Kawashima
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sugano
authors.forename: Shinji
authors.initials: S
authors.lastname: Sakurai
authors.forename: Takaaki
authors.initials: T
authors.lastname: Sano
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D018267:Carcinoma, Acinar Cell / Q000378:metabolism / Q000473:pathology*; D002283:Carcinoma, Bronchogenic / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013906:Thoracoscopy