The effects of Goami No. 2 rice, a natural fiber-rich rice, on body weight and lipid metabolism.
OBJECTIVE
Increased intake of dietary fiber reduces the risk of obesity and type 2 diabetes. We assessed the effects of a fiber-rich diet on body weight, adipokine concentrations, and the metabolism of glucose and lipids in non-obese and obese subjects in Korea, where rice is the main source of dietary carbohydrates.


METHODS
Eleven healthy, non-obese and 10 obese subjects completed two 4-week phases of individual isoenergetic food intake. During the control diet phase, subjects consumed standard rice; during the modified diet phase, subjects consumed equal proportions of fiber-rich Goami No. 2 rice and standard rice. We used a randomized, controlled, crossover study design with a washout period of 6 weeks between the two phases.


RESULTS
After the modified diet phase, body weight was significantly lower in both the non-obese and obese subjects (non-obese, 57.0 +/- 2.9 vs. 56.1 +/- 2.8 kg, p = 0.001; obese, 67.7 +/- 2.1 vs. 65.7 +/- 2.0 kg, p < 0.001 for before vs. after). The BMI was significantly lower in obese subjects (26.9 +/- 0.5 vs. 26.0 +/- 0.6 kg/m2, p < 0.001). The modified diet was associated with lower serum triacylglycerol (p < 0.01), total cholesterol (p < 0.01), low-density lipoprotein cholesterol (p < 0.05), and C-peptide (p < 0.05) concentrations in the obese subjects.


CONCLUSIONS
These results indicate that fiber-rich Goami No. 2 rice has beneficial effects and may be therapeutically useful for obese subjects.
Lee
K W
KW
Department of Endocrinology and Metabolism, Ajou University School of Medicine, San-5 Wonchon Dong, Yongtong Gu, 443-721, Suwon, Republic of Korea. LKW65@ajou.ac.kr
Song
K E
KE
Lee
H S
HS
Kim
Y K
YK
Lee
S W
SW
Kim
D J
DJ
Hwang
W S
WS
Choe
S J
SJ
Kim
Y S
YS
Kim
T Y
TY
D052242:Adiponectin / Q000097:blood; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D001835:Body Weight / Q000187:drug effects* / Q000502:physiology; D002096:C-Peptide / Q000097:blood; D002784:Cholesterol / Q000097:blood; D018592:Cross-Over Studies; D004040:Dietary Carbohydrates / Q000378:metabolism / Q000494:pharmacology; D004043:Dietary Fiber / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D020738:Leptin / Q000097:blood; D050356:Lipid Metabolism / Q000187:drug effects* / Q000502:physiology; D008297:Male; D009765:Obesity / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D012275:Oryza; D052243:Resistin / Q000097:blood; D014280:Triglycerides / Q000097:blood
D052242:Adiponectin; D001786:Blood Glucose; D002096:C-Peptide; D002784:Cholesterol; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D006442:Glycated Hemoglobin; D020738:Leptin; D052243:Resistin; D014280:Triglycerides