title: Multifocal lymphangioendotheliomatosis with thrombocytopenia.
abstract: Multifocal lymphangioendotheliomatosis with thrombocytopenia is an extremely rare disease. This condition manifests as diffuse congenital vascular lesions in the skin and gastrointestinal tract leading to severe gastrointestinal bleeding and thrombocytopenia. Histopathologic and immunohistochemical studies of vascular lesions demonstrate a lymphatic endothelial cell origin. Treatment often is not satisfactory. We herein describe a 4-week-old infant with this uncommon clinicopathologic entity.
authors.affiliation: Department of Dermatology, University of Toronto, Canada.
authors.forename: Jensen
authors.initials: J
authors.lastname: Yeung
authors.forename: Gino
authors.initials: G
authors.lastname: Somers
authors.forename: Sandra
authors.initials: S
authors.lastname: Viero
authors.forename: Elena
authors.initials: E
authors.lastname: Pope
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D041981:Gastrointestinal Tract / Q000098:blood supply*; D006390:Hemangioendothelioma / Q000150:complications* / Q000151:congenital / Q000188:drug therapy / Q000473:pathology*; D006396:Hematemesis / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007231:Infant, Newborn; D008202:Lymphangioma / Q000150:complications* / Q000151:congenital / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D013194:Staining and Labeling; D013921:Thrombocytopenia / Q000209:etiology*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D014750:Vincristine