title: Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.
abstract: Between 1970 and 2003, seven cases of human dura mater-associated Creutzfeldt-Jakob disease (CJD) were identified in the UK. Furthermore, we identified a case of CJD in a porcine dura graft recipient. The mean incubation period of the human dura mater cases was 93 (range 45-177) months. The clinico-pathological features of the cases are described and compared with cases previously reported in the world literature.
authors.affiliation: National CJD Surveillance Unit, Bryan Matthews Building, Western General Hospital, Edinburgh EH4 2XU, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: Heath
authors.forename: R A
authors.initials: RA
authors.lastname: Barker
authors.forename: T F G
authors.initials: TF
authors.lastname: Esmonde
authors.forename: P
authors.initials: P
authors.lastname: Harvey
authors.forename: R
authors.initials: R
authors.lastname: Roberts
authors.forename: P
authors.initials: P
authors.lastname: Trend
authors.forename: M W
authors.initials: MW
authors.lastname: Head
authors.forename: C
authors.initials: C
authors.lastname: Smith
authors.forename: J E
authors.initials: JE
authors.lastname: Bell
authors.forename: J W
authors.initials: JW
authors.lastname: Ironside
authors.forename: R G
authors.initials: RG
authors.lastname: Will
authors.forename: R S G
authors.initials: RS
authors.lastname: Knight
mesh_terms: D000328:Adult; D000818:Animals; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000473:pathology* / Q000635:transmission*; D004388:Dura Mater / Q000473:pathology* / Q000637:transplantation*; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D011159:Population Surveillance; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000009:adverse effects*; D006113:United Kingdom / Q000453:epidemiology