title: Evaluation of influenza vaccination in health-care workers, using rapid antigen detection test.
abstract: A study was conducted to assess the effectiveness of trivalent influenza vaccine in preventing influenza and reducing absenteeism in health-care workers of Gifu Red Cross Hospital during the 2002-2003 influenza season. Questionnaires were distributed to 370 health-care workers, and 366 were returned showing that 237 had received influenza vaccine and 129 were unvaccinated. The criterion for influenza was febrile episodes with a positive reaction on a rapid antigen detection test. Among vaccine recipients, the number of influenza infections was 3.4 per 100 subjects, compared with 8.5 per 100 subjects in nonrecipients (P = 0.034), and the number of days absent from work per 100 subjects was 9.5, compared with 15.1 per 100 subjects in nonrecipients (P = 0.0003). The prevalence of adverse reactions to the vaccine was rather low. No serious adverse reactions were recorded and no one was absent from work because of adverse reactions. It is concluded that influenza vaccine is effective in preventing influenza and reducing absenteeism in health-care workers. The results of this study support recommendations for influenza vaccination in health-care workers.
authors.affiliation: Department of Internal Medicine, Gifu Red Cross Hospital, 3-36 Iwakura-cho, Gifu 502-8511, Japan. gifu-med@gifu.email.ne.jp
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Ito
authors.forename: Hanako
authors.initials: H
authors.lastname: Sumi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Kato
mesh_terms: D000041:Absenteeism; D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000032:analysis*; D005260:Female; D006282:Health Personnel; D006801:Humans; D007252:Influenza Vaccines / Q000276:immunology / Q000627:therapeutic use*; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged
chemical_list: D000956:Antigens, Viral; D007252:Influenza Vaccines