title: Oral hypertonic glucose solution in the treatment of infantile colic.
abstract: BACKGROUND
  Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC.
  
  
  METHODS
  A total of 25 infants diagnosed as typical IC were given 1 mL of 30% glucose solution or sterile water for 4 days consecutively, in a randomized, double blind crossover trial. The effect was measured by parents' scoring.
  
  
  RESULTS
  Parents reported varying degrees of improvement in 16 infants (64%) given glucose solution, and in 12 infants (48%) given placebo. Comparison of treatment modalities were statistically significant (P = 0.031). There was no side-effect during treatments.
  
  
  CONCLUSIONS
  The present study revealed that 30% glucose was effective in the treatment of IC. Since oral glucose solution is natural, safe, cheap and easily achievable, it might be considered as an alternative therapy.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akçam
authors.forename: Aygen
authors.initials: A
authors.lastname: Yilmaz
mesh_terms: D003085:Colic / Q000188:drug therapy*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D005950:Glucose Solution, Hypertonic / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D005950:Glucose Solution, Hypertonic