Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial.
OBJECTIVE
To determine the effects of age related, structured educational programmes on the management of moderate to severe atopic dermatitis in childhood and adolescence.


METHODS
Multicentre, randomised controlled trial.


METHODS
Seven hospitals in Germany.


METHODS
Parents of children with atopic dermatitis aged 3 months to 7 years (n = 274) and 8-12 years (n = 102), adolescents with atopic dermatitis aged 13-18 years (n = 70), and controls (n = 244, n = 83, and n = 50, respectively).


METHODS
Group sessions of standardised intervention programmes for atopic dermatitis once weekly for six weeks or no education (control group).


METHODS
Severity of eczema (scoring of atopic dermatitis scale), subjective severity (standardised questionnaires), and quality of life for parents of affected children aged less than 13 years, over 12 months.


RESULTS
Significant improvements in severity of eczema and subjective severity were seen in all intervention groups compared with control groups (total score for severity: age 3 months to 7 years - 17.5, 95% confidence intervals - 19.6 to - 15.3 v - 12.2, - 14.3 to - 10.1; age 8-12 years - 16.0, - 20.0 to - 12.0 v - 7.8, - 11.4; - 4.3; and age 13-18 years - 19.7, - 23.7 to - 15.7 v - 5.2, - 10.5 to 0.1). Parents of affected children aged less than 7 years experienced significantly better improvement in all five quality of life subscales, whereas parents of affected children aged 8-12 years experienced significantly better improvement in three of five quality of life subscales.


CONCLUSIONS
Age related educational programmes for the control of atopic dermatitis in children and adolescents are effective in the long term management of the disease.
Staab
Doris
D
Department of Paediatric Pulmonology and Immunology, Charité, Humboldt University, Berlin.
Diepgen
Thomas L
TL
Fartasch
Manigé
M
Kupfer
Jörg
J
Lob-Corzilius
Thomas
T
Ring
Johannes
J
Scheewe
Sibylle
S
Scheidt
Reginald
R
Schmid-Ott
Gerhard
G
Schnopp
Christina
C
Szczepanski
Rüdiger
R
Werfel
Thomas
T
Wittenmeier
Marita
M
Wahn
Ulrich
U
Gieler
Uwe
U
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000517:prevention & control / Q000628:therapy*; D005858:Germany; D006801:Humans; D007223:Infant; D010290:Parents / Q000523:psychology; D010353:Patient Education as Topic / Q000379:methods*; D011537:Pruritus / Q000209:etiology; D011788:Quality of Life; D012648:Self Care / Q000379:methods; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016896:Treatment Outcome