title: Three cases of pancreatic serous cystadenoma and endocrine tumour.
abstract: OBJECTIVE
  To report three cases of serous cystadenoma and endocrine tumour in the same pancreas, to review the literature and to evaluate the clinicopathological features of the tumours.
  
  
  METHODS
  Three women (71, 57 and 31 years old) were admitted to hospital, two for diseases unrelated to the pancreas and the third for increasing obstructive jaundice in von Hippel-Lindau disease. Preoperative examination showed two distinct lesions in the first patient and only cystic lesions in the other two.
  
  
  RESULTS
  Histological examination of the pancreas showed one serous oligocystic adenoma associated with a benign, well-differentiated endocrine tumour, one serous oligocystic adenoma associated with an endocrine microadenoma, and a von Hippel-Lindau-related cystic neoplasm with a well-differentiated endocrine carcinoma.
  
  
  CONCLUSIONS
  Serous cystadenoma associated with endocrine tumour shows some clinicopathological differences with respect to the two tumours considered separately, and with respect to von Hippel-Lindau-related cases, although there is no convincing evidence at present to justify considering this association as a separate entity.
authors.affiliation: Department of Oncological and Surgical Sciences, Section of Pathological Anatomy, University of Padova, Padova, Italy. stella.blandamura@unipd.it
authors.forename: Stella
authors.initials: S
authors.lastname: Blandamura
authors.forename: Anna
authors.initials: A
authors.lastname: Parenti
authors.forename: Barbara
authors.initials: B
authors.lastname: Famengo
authors.forename: Alessandra
authors.initials: A
authors.lastname: Canesso
authors.forename: Paolo
authors.initials: P
authors.lastname: Moschino
authors.forename: Claudio
authors.initials: C
authors.lastname: Pasquali
authors.forename: Sara
authors.initials: S
authors.lastname: Pizzi
authors.forename: Vincenza
authors.initials: V
authors.lastname: Guzzardo
authors.forename: Vito
authors.initials: V
authors.lastname: Ninfo
mesh_terms: D000328:Adult; D000368:Aged; D018293:Cystadenoma, Serous / Q000378:metabolism / Q000473:pathology*; D004701:Endocrine Gland Neoplasms / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D009378:Neoplasms, Multiple Primary / Q000378:metabolism / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology*; D006623:von Hippel-Lindau Disease / Q000378:metabolism / Q000473:pathology
chemical_list: D009363:Neoplasm Proteins