Cucurbitacin glucosides from Citrullus colocynthis.
A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species.
Nayab
Durey
D
International Center for Chemical Sciences, HEJ, Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Ali
Dildar
D
Arshad
Nuzhat
N
Malik
Abdul
A
Choudhary
M Iqbal
MI
Ahmed
Zaheer
Z
D029773:Citrullus; D054728:Cucurbitacins; D005638:Fruit; D005960:Glucosides / Q000737:chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry
D005960:Glucosides; D010936:Plant Extracts; D014315:Triterpenes; D054728:Cucurbitacins