title: Primary cutaneous paraganglioma of the scalp.
abstract: Paragangliomas are neuroendocrine tumors that arise in relation to the sympathetic or parasympathetic ganglia of the autonomic nervous system. Rarely, they are reported in unusual locations such as the urinary bladder, prostate, and uterus. Herein, we report a case of primary cutaneous paraganglioma of the scalp in a child. The tumor was studied histologically, immunohistochemically, and ultrastructurally. This case might represent an aberrant migration of neural crest cells in their descent toward the branchial arches. In addition, it highlights the complex interaction of the neural crest and branchial arches/clefts during embryogenesis.
authors.affiliation: Department of Dermatology, University of Southern California, Keck School of Medicine, CA, USA.
authors.forename: Payam
authors.initials: P
authors.lastname: Saadat
authors.forename: Sarka
authors.initials: S
authors.lastname: Cesnorek
authors.forename: Ramin
authors.initials: R
authors.lastname: Ram
authors.forename: Linda
authors.initials: L
authors.lastname: Kelly
authors.forename: Manjunath
authors.initials: M
authors.lastname: Vadmal
mesh_terms: D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D010235:Paraganglioma / Q000378:metabolism / Q000473:pathology*; D012535:Scalp; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*