title: Solitary intracranial tuberculoma in patients without immuno-suppression: a report of three cases.
abstract: OBJECTIVE
  Poverty, drug resistance and the advent of human immunodeficiency virus infection (HIV) have led to a recent upsurge in the incidence of tuberculosis including intracranial tuberculosis. In this article, we report 3 patients who had solitary brain tuberculomas and were otherwise healthy to underscore the importance of continuing vigilance for this disease.
  
  
  METHODS
  Three patients (57 years, female; 52 years, male; 7 years male) presented to our unit with features of intracranial tumours. They were all HIV negative with no previous history of tuberculosis. Cranial computed tomography scans demonstrated uniformly contrast enhancing falcine supratentorial masses in the adult patients and a cerebellar hemispheric lesion with peripheral contrast enhancement in the paediatric patient
  
  
  METHODS
  All the patients had gross total tumour excision. The histology confirmed a tuberculoma. They all had antituberculous therapy after histological confirmation. The outcome was good in all the patients.
  
  
  CONCLUSIONS
  Intracranial tuberculoma can occur in otherwise healthy individuals and should always be considered in the differential diagnosis of solitary intracranial mass lesions in sub-Saharan Africans so that minimally invasive procedures can be used to establish the correct diagnosis.
authors.affiliation: Department of Surgery, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, and University of Ibadan College Hospital, Nigeria.
authors.forename: A A
authors.initials: AA
authors.lastname: Adeolu
authors.forename: M T
authors.initials: MT
authors.lastname: Shokunbi
authors.forename: A O
authors.initials: AO
authors.lastname: Malomo
authors.forename: E A A
authors.initials: EA
authors.lastname: Akang
authors.forename: M O
authors.initials: MO
authors.lastname: Obajimi
authors.forename: E O
authors.initials: EO
authors.lastname: Komolafe
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D002531:Cerebellum; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D016862:Tuberculoma, Intracranial / Q000000981:diagnostic imaging* / Q000276:immunology
chemical_list: D000995:Antitubercular Agents