The influence of maternal ketonuria on fetal well-being tests in postterm pregnancy.
BACKGROUND
Although it is well-known that postterm pregnancies are associated with the risk of perinatal morbidity and mortality, a comprehensive study on its management is lacking. The aim of present study was to determine whether ketonuria is associated with abnormal fetal test results in pregnancies >40 weeks of gestation.


METHODS
In this analytical cross sectional study, a total of 360 pregnant women with gestational age of >40 weeks were evaluated in two hospitals during 2003 - 2004. For each woman, urinary ketones, glucose, pH, proteins, and specific gravity were measured by total screen LSG tapes (Rapignost); in addition, biophysical profile test was recorded and the amniotic fluid index was assessed by ultrasonography.


RESULTS
Ketonuria was found in 34 women (9.44%). Statistical analyses showed that maternal ketonuria was associated with oligohydramnios, abnormal fetal tests, and a significant increase in fetal heart rate decelerations.


CONCLUSIONS
Patients with clinically-detectable ketonuria have higher risk for abnormal fetal tests in comparison with those without the disease.
Hamdi
Kobra
K
Department of Obstetrics and Gynecology, Al-Zahra Hospital, Tehran, Iran.
Bastani
Parvin
P
Gafarieh
Roya
R
Mozafari
Hadi
H
Hashemi
Seyed-Hassan
SH
Ghotbi
Mohammad-Hamed
MH
D000328:Adult; D000653:Amniotic Fluid; D003430:Cross-Sectional Studies; D003681:Dehydration / Q000150:complications; D005260:Female; D005316:Fetal Distress; D005865:Gestational Age; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D007657:Ketone Bodies / Q000652:urine*; D016104:Oligohydramnios / Q000209:etiology*; D011247:Pregnancy; D011273:Pregnancy, Prolonged / Q000652:urine*; D013046:Specific Gravity
D007657:Ketone Bodies