Neurobrucellosis mimicking cerebral tumor: case report and literature review.
We are reporting a case of neurobrucellosis that was clinically and radiologically indistinguishable from a cerebral tumor. The histological diagnosis was granulomatous encephalitis. The diagnosis was established by enzyme-linked immunosorbent assay (ELISA), detecting high levels of Ig G and Ig M Brucella antibodies in the serum and the cerebrospinal fluid. We suggest that patients with granulomatous encephalitis, without a clear etiological agent, should be studied for Brucella.
Miguel
Pilar San
PS
Department of Pathology, Centro Médico POVISA, C/Salamanca No. 5, 36211 Vigo, Pontevedra, Spain. psanmiguel@povisa.es
Fernández
Gabriel
G
Vasallo
Francisco J
FJ
Hortas
Mario
M
Lorenzo
José Ramón
JR
Rodríguez
Irene
I
Ortiz-Rey
José Antonio
JA
Antón
Iosu
I
D000328:Adult; D001921:Brain / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis*; D002006:Brucellosis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000379:methods; D014057:Tomography, X-Ray Computed