title: [Polymorphism of dental formula and segregation of its variants in a pedigree of kerry blue terrier dogs].
abstract: Polymorphism of the dental formula was analyzed in a sophisticated pedigree of Kerry Blue Terrier. A lack of one or more lower premolars was observed in some dogs. Two different patterns of missing teeth were identified. One pattern consisted in agenesis of a second premolar, often in combination with agenesis of neighbor teeth, including the fourth premolar. In the second pattern, agenesis of a fourth premolar was expressed as an isolated abnormality. It was shown previously that the first pattern is inherited as a recessive trait with near complete penetrance. In this work, the control of a major-gene was demonstrated for the second pattern. This abnormality develops in 70-80% of mutant homozygotes and in no more than 20% of heterozygotes and wild-type homozygotes. It was shown that the two dentition abnormalities are controlled by different genes, which were designated LPA2 and LPA4 (Lower Premolar Agenesis).
authors.forename: T I
authors.initials: TI
authors.lastname: Aksenovich
authors.forename: A V
authors.initials: AV
authors.lastname: Kulikova
authors.forename: S P
authors.initials: SP
authors.lastname: Kniazev
authors.forename: I V
authors.initials: IV
authors.lastname: Zorkal'tseva
authors.forename: P M
authors.initials: PM
authors.lastname: Borodin
mesh_terms: D000818:Animals; D000848:Anodontia / Q000235:genetics* / Q000662:veterinary*; D001641:Bicuspid / Q000002:abnormalities*; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs / Q000002:abnormalities* / Q000033:anatomy & histology; D005796:Genes; D006579:Heterozygote; D006720:Homozygote; D009154:Mutation; D010375:Pedigree