[Percutaneous ethanol injection for the treatment of thyroid nodules].
To verify the effectiveness of percutaneous ethanol injection (PEI) in the treatment of thyroid nodules (TN), we analyzed 86 TN from 77 patients before and after one or two sessions of PEI. The medians of the initial and final volumes were: 3.5 mL (range 0.3-82.7) and 1.8 mL (range 0-29.4). Seven percent of the nodules disappeared and the mean nodule size reduction was 52.6% (p< 0.0001). After ethanol injection, the median volume reduction was: 37.3% (range -39.0-82.6) for solid; 53.5% (14.6-88.0) for mostly solid; 58.0% (21.0-64.5) for mixed; 71.0% (18.8-100.0) for mostly cystic and 90.0% (45.9-100.0) for cystic lesions. Furthermore, we compared the variation of the greatest diameter of TN, without any treatment and after PEI, and found this difference statistically significant (p< 0.00001). Pain was the most common complication, although this was mostly described as moderate (27.6%). We conclude that PEI is an efficient and safe treatment option for benign TN.
Alcântara-Jones
Daysi M de
DM
Universidade Federal da Bahia, RJ. daysijones@terra.com.br
Araújo
Leila Maria Batista
LM
Almeida
Alessandro de M
Ade M
Jones
Daniel de Alcântara
Dde A
Cardoso
Lázaro José Góes
LJ
Passos
Marize Carvalho
MC
D000328:Adult; D003560:Cysts / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome; D014463:Ultrasonography
D012597:Sclerosing Solutions; D000431:Ethanol