title: [Interferon system and proinflammatory cytokine IL-1beta in frequently ill children during the remission period].
abstract: Investigation of cytokines IL-1beta, INF-alpha and INF-gamma in frequently ill children in the period of remission was the main objective of the study. Two groups of children were investigated: a) 8 preschool children aged 4-6; b) 20 children aged 7-12. Interferon alpha and gamma were studied in the blood serum by Soloviov and Bektemirov method. IL-1beta was studied in the blood serum by hard phased immunoenzyme. Results were analysed by the computer program SPSS V 11.5. The patients were tested twice. During the first test indicators of interferon alpha and gamma were studied, and during the second test, performed within the 1-2 years time period, indicators of IL -1beta were added. It was found that the level of IL -1beta (p<0,05) was elevated.
authors.forename: M M
authors.initials: MM
authors.lastname: Dzhibuti
authors.forename: V L
authors.initials: VL
authors.lastname: Rusidze
authors.forename: M V
authors.initials: MV
authors.lastname: Tsulukidze
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000276:immunology*; D007375:Interleukin-1 / Q000276:immunology*; D008297:Male; D012074:Remission Induction; D012141:Respiratory Tract Infections / Q000276:immunology*
chemical_list: D007375:Interleukin-1; D007371:Interferon-gamma