title: Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage.
abstract: Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative stress in these organisms can give important information about their physiological status and also about environmental health. Bivalves have been proposed as good sentinel organisms in pollution monitoring studies through the analysis of biochemical biomarkers, and most of the biomarkers analyzed are those related to oxidative stress. However, it is very important to know how other environmental factors not associated to the presence of pollutants might affect these parameters. We have studied a series of mechanisms related to oxidative stress in mussels which inhabit the Brazilian coast, especially in Perna perna species, subjected to different stress conditions, such as the exposure to different contaminants in the laboratory and in the field, the exposure of mussels to air and re-submersion, simulating the tidal oscillations, and in mussels collected at different seasons. Both oxidative damage levels and antioxidant defense systems were strongly affected by the different environmental stress. This review summarizes the data obtained in some studies carried out in bivalves from the Brazilian coast.
authors.affiliation: Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, CP 26.077, 05513-970, São Paulo, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Alves de Almeida
authors.forename: Afonso
authors.initials: A
authors.lastname: Celso Dias Bainy
authors.forename: Ana
authors.initials: A
authors.lastname: Paula de Melo Loureiro
authors.forename: Glaucia
authors.initials: G
authors.lastname: Regina Martinez
authors.forename: Sayuri
authors.initials: S
authors.lastname: Miyamoto
authors.forename: Janice
authors.initials: J
authors.lastname: Onuki
authors.forename: Lívea
authors.initials: L
authors.lastname: Fujita Barbosa
authors.forename: Camila
authors.initials: C
authors.lastname: Carrião Machado Garcia
authors.forename: Fernanda
authors.initials: F
authors.lastname: Manso Prado
authors.forename: Graziella
authors.initials: G
authors.lastname: Eliza Ronsein
authors.forename: Carlos
authors.initials: C
authors.lastname: Alexandre Sigolo
authors.forename: Cláudia
authors.initials: C
authors.lastname: Barbosa Brochini
authors.forename: Ana
authors.initials: A
authors.lastname: Maria Gracioso Martins
authors.forename: Marisa
authors.initials: M
authors.lastname: Helena Gennari de Medeiros
authors.forename: Paolo
authors.initials: P
authors.lastname: Di Mascio
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D049872:Bivalvia / Q000502:physiology*; D001938:Brazil; D004249:DNA Damage; D004463:Ecology; D015227:Lipid Peroxidation; D008386:Marine Biology; D018384:Oxidative Stress; D049883:Perna / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D000975:Antioxidants; D017382:Reactive Oxygen Species