Antimicrobial C-glucoside from aerial parts of Diospyros nigra.
A new C-alkylglucoside, diospyrodin [beta-1C-(1'S*,2'R*,3'R*,4'S*-1',2',3',4',5'-pentahydroxypentyl)-glucopyranoside] (1) has been isolated as its nonaacetate from the leaves and stems of Diospyros nigra. Its structure was elucidated on the basis of chemical and spectral properties and a single crystal X-ray analysis. It showed antimicrobial activity against Gram-positive and Gram-negative bacteria.
Dinda
Biswanath
B
Department of Chemistry, Tripura University, Suryamaninagar, Agartala-799 130, India. dindabtu@rediffmail.com
Bhattacharya
Abhijit
A
De
Utpal Chandra
UC
Arima
Shiho
S
Takayanagi
Hiroaki
H
Harigaya
Yoshihiro
Y
D000107:Acetylation; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D029788:Diospyros / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D005960:Glucosides; D010936:Plant Extracts; C511379:diospyrodin (beta-1C-(1'S*,2'R*,3'R*,4'S*-1',2',3',4',5'-pentahydroxypentyl)-glucopyranoside)