title: Metabolic alteration transients during paroxysmal activity in an epileptic patient with fixation-off sensitivity: a case study.
abstract: The purpose of this study was to investigate short-time metabolic variations related to continuous epileptic activity elicited by fixation-off sensitivity (FOS). Time-resolved magnetic resonance spectroscopy was performed on a patient on whom previous clinical findings clearly indicated presence of FOS. The epileptic focus was localized with a simultaneous electroencephalographic and functional magnetic resonance imaging study. The results showed a linear increase of the sum of glutamate and glutamine with time of paroxysmal activity in epileptic focus and much greater concentration of choline-containing compounds in focus than in the contralateral side.
authors: Museo storico della fisica e Centro di studi e ricerche Enrico Fermi, 00184 Rome, Italy.
authors: Federico
authors: F
authors: Giove
authors: Girolamo
authors: G
authors: Garreffa
authors: Stefano
authors: S
authors: Peca
authors: Marco
authors: M
authors: Carní
authors: Maria Antonietta
authors: MA
authors: Macrì
authors: Carlo
authors: C
authors: Di Bonaventura
authors: Anna Elisabetta
authors: AE
authors: Vaudano
authors: Anna Teresa
authors: AT
authors: Giallonardo
authors: Massimiliano
authors: M
authors: Prencipe
authors: Luigi
authors: L
authors: Bozzao
authors: Patrizia
authors: P
authors: Pantano
authors: Claudio
authors: C
authors: Colonnese
authors: Bruno
authors: B
authors: Maraviglia