title: Biophysical and phenomenological models of multiple spike interactions in spike-timing dependent plasticity.
abstract: Spike-timing dependent plasticity (STDP) is a form of associative synaptic modification which depends on the respective timing of pre- and post-synaptic spikes. The biophysical mechanisms underlying this form of plasticity are currently not known. We present here a biophysical model which captures the characteristics of STDP, such as its frequency dependency, and the effects of spike pair or spike triplet interactions. We also make links with other well-known plasticity rules. A simplified phenomenological model is also derived, which should be useful for fast numerical simulation and analytical investigation of the impact of STDP at the network level.
authors: Integrative and Computational Neuroscience Unit (UNIC), CNRS, Gif-sur-Yvette, France.
authors: Mathilde
authors: M
authors: Badoual
authors: Quan
authors: Q
authors: Zou
authors: Andrew P
authors: AP
authors: Davison
authors: Michael
authors: M
authors: Rudolph
authors: Thierry
authors: T
authors: Bal
authors: Yves
authors: Y
authors: Frégnac
authors: Alain
authors: A
authors: Destexhe