title: Magnitude and time course of arterial vascular adaptations to inactivity in humans.
abstract: We demonstrate that extensive arterial vascular adaptations occur within 3-8 wk of inactivity in humans. We put forth the hypothesis that the diameter decrease represents an adaptation to a lack of variation in peak shear stress. Furthermore, an enhanced flow-mediated dilation in deconditioned arteries implies that functional vascular adaptations to inactivity are not simply the inverse of adaptations to exercise.
authors: Department of Physiology, Radboud University Nijmegen Medical Center, The Netherlands.
authors: Patricia C E
authors: PC
authors: de Groot
authors: Michiel W P
authors: MW
authors: Bleeker
authors: Maria T E
authors: MT
authors: Hopman