The prevalence of pulmonary parenchymal tuberculosis in patients with tuberculous pleuritis.
OBJECTIVE
To examine the prevalence and characteristics of parenchymal tuberculous pleuritis in adult patients.


METHODS
Prospective cohort study.


METHODS
Three hospitals affiliated with Seoul National University in South Korea.


METHODS
All patients > 15 years old with a diagnosis of tuberculous pleuritis were enrolled prospectively between January 1, 2004, and October 31, 2004.


METHODS
Diagnostic thoracocentesis and CT of the chest were done for each patient. Acid-fast bacilli (AFB) smears and cultures for Mycobacterium tuberculosis were requested if patients produced any sputum. A board-certified radiologist reviewed the chest radiographs for the presence and characteristics of any lesions.


RESULTS
One hundred six patients with tuberculous pleuritis were enrolled (median age, 53 years; range 16 to 89 years). Among them, 33 patients (31%) had sputum or bronchial washing findings positive for AFB smears or for M tuberculosis by culture. Lung parenchymal lesions were observed in 91 of the patients (86%) using chest CT; 39 patients (37%) with parenchymal lesions had radiographic characteristics of active pulmonary tuberculosis. In total, 62 patients (59%) had bacteriologically or radiographically active pulmonary tuberculosis. In addition, 78 patients (74%) had features of reactivated pulmonary tuberculosis.


CONCLUSIONS
Lung parenchymal lesions were more common in this series of patients with tuberculous pleuritis than has been reported in previous studies. The patients mostly had radiographic features of reactivated, rather than primary, tuberculosis.
Kim
Hee Joung
HJ
Division of Pulmonary and Critical Care Medicine, Department of Medicine and Lung Institute, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul, 110-744, South Korea.
Lee
Hyun Ju
HJ
Kwon
Sung-Youn
SY
Yoon
Ho Il
HI
Chung
Hee Soon
HS
Lee
Choon-Taek
CT
Han
Sung Koo
SK
Shim
Young-Soo
YS
Yim
Jae-Joon
JJ