title: Therapeutic effects of beta-thujaplicin eardrops on canine Malassezia-related otitis externa.
abstract: An eardrop solution of beta-thujaplicin was examined for therapeutic effects on canine Malassezia-related otitis externa. Half to one ml of beta-thujaplicin solution of 100 microg/ml including DMSO 2% was injected everyday into both external ear canals of 31 cases for test-of-cure agreement. Fifteen score phases were established from the symptoms and cerumen smear biopsy findings, and score changes were recorded at least once a week. The means of the second and the third inspection day scores decreased significantly more than the previous value of each. In addition, the numbers of yeast-like organisms clearly decreased. These results suggest that beta-thujaplicin eardrops are effective for Malassezia-related otitis externa in dogs.
authors: Department of Veterinary Clinical Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan.
authors: Yasuyuki
authors: Y
authors: Nakano
authors: Saburo
authors: S
authors: Matsuo
authors: Hiroyuki
authors: H
authors: Tani
authors: Kazumi
authors: K
authors: Sasai
authors: Eiichiroh
authors: E
authors: Baba