title: Regioselective and stereospecific cleavage of a terminal oxirane system: a novel synthetic approach to lipid mediator congeners--1,2(2,3)-diacyl-3(1)-halo-sn-glycerols.
abstract: Glycidyl esters upon treatment with a mixture of carboxylic acid anhydride (CAA) and trimethylsilyl halide (TMSX) in the presence of tetra-n-butylammonium halide (Bu(4)NX, X=Cl, Br or I) undergo stereospecific and regioselective opening of the oxirane ring to afford mixed-(or mono)-acid 1,2(2,3)-diacyl-3(1)-halo-sn-glycerols in high yields.
authors: Department of Chemical Technology, University of Plovdiv, 24 Tsar Assen St., Plovdiv 4000, Bulgaria. js@organ.su.se
authors: Stephan D
authors: SD
authors: Stamatov
authors: Jacek
authors: J
authors: Stawinski