title: [Pregnancy complications as a risk factor for metabolic and cardiovascular disease in later life].
abstract: In recent years several large epidemiological studies have been published that demonstrate that women who experience gestational diabetes, pregnancy-induced hypertension or pre-eclampsia have an increased risk of developing type-2 diabetes mellitus and cardiovascular disease. 15-50% of women who experience gestational diabetes develop type-2 diabetes mellitus; the risk is particularly high in those who require insulin therapy during pregnancy. - Chronic hypertension frequently develops years after a pregnancy complicated by pregnancy-induced hypertension, especially in women who have had pregnancy-induced hypertension in multiple pregnancies. Women who experience pre-eclampsia in the first 36 weeks of pregnancy or in multiple pregnancies have an increased risk of cardiovascular morbidity and mortality in later life. Therefore gestational diabetes, pregnancy-induced hypertension and pre-eclampsia provide an opportunity to identify individuals with an increased risk of type-2 diabetes mellitus and cardiovascular disease at an early age. This may create new perspectives on prevention.
authors: Universitair Medisch Centrum Utrecht, afd. Perinatologie, Utrecht.
authors: J M
authors: JM
authors: Sikkema
authors: H W
authors: HW
authors: Bruinse
authors: G H A
authors: GH
authors: Visser
authors: A
authors: A
authors: Franx