title: [Intralesional injection of Pingyangmycin for treatment of venous-venular malformation in the maxillofacial regions of children: report of 306 cases].
abstract: OBJECTIVE
  To evaluate the effect of intralesional injection of Pingyangmycin (PYM) for treatment of venous-venular malformation in the maxillofacial regions of children.
  
  
  METHODS
  The medical records of 306 patients with venous-venular malformation in the maxillofacial regions between January 1997 and June 2005 were reviewed. One hundred and twenty-three of the patients were men, and one hundred and eighty-three were woman, the sex ratio was 1:1.49. The patients aged from one month to 12 years, 172 were less than 6 months (56.21%). Pingyangmycin was injected into the center or in the vicinity of the venous-venular malformations, and repeated every 7 to 10 days. This cycle were repeated 3 to 5 times when necessary.
  
  
  RESULTS
  Three hundred and six patients were followed up for 6 to 102 months. Complete response was obtained in 156 cases (50.98%), partial response in 116 cases (37.91%), and improvement in 34 cases (11.11%). The overall response rate was 100%, and the curative rate was 88.89%.
  
  
  CONCLUSIONS
  This method is safe, simple and effective for venous-venular malformation in the maxillofacial regions of children.
authors: Department of Stomatology, Nanjing General Hospital of PLA, Nanjing 210002, Jiangsu Province, China. shoujiajun10@sina.com
authors: Bo-quan
authors: BQ
authors: Shou
authors: Wei-dong
authors: WD
authors: Shou
authors: Zhen
authors: Z
authors: Yang
authors: Zhao-ye
authors: ZY
authors: Meng
authors: Sen-lin
authors: SL
authors: Zhang
authors: Gang
authors: G
authors: Cao
authors: Zhen
authors: Z
authors: Dong