Novel calixarene hemisphere synthesized via pinacol rearrangement of [2.1.2.1]metacyclophane.
[reaction: see text] Tetramethoxy[2.1.2.1]metacyclophane ([2.1.2.1]MCP) was prepared by the pinacol coupling reaction of diphenylmethane dialdehyde. The treatment of [2.1.2.1]MCP with trimethylsilyl chloride and sodium iodide yielded two unexpected calixarene derivatives, cone (hemisphere) and 1,2-alternate types, instead of octahydroxy[2.1.2.1]MCP. The X-ray structure of the cone-type derivative and its inclusion property with acetonitrile were also discussed.
Sawada
Tsuyoshi
T
Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Graduate School of Science and Technology, Kumamoto University, Japan. sawada@kumamoto-u.ac.jp
Nishiyama
Yousuke
Y
Tabuchi
Wataru
W
Ishikawa
Makoto
M
Tsutsumi
Emi
E
Kuwahara
Yutaka
Y
Shosenji
Hideto
H