Combinatorial discovery of fluorophores and fluorescent probes.
The properties of organic fluorophores are difficult to predict, even in simple cases. Fluorescent probes--which combine fluorescent properties with the equally challenging problem of molecular recognition--are even more difficult to develop. Combinatorial approaches to the development of such molecules are a new but promising endeavor, and reviewing the state of the art delineates the near-and long-term possibilities.
Finney
Nathaniel S
NS
Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Switzerland. finney@unizh.ch