title: Efficacy of contact lens storage solutions against different acanthamoeba strains.
abstract: OBJECTIVE
  This study was undertaken in order to determine the susceptibility of acanthamoebae to various contact lens disinfecting systems, with respect to type of disinfectant and exposure time.
  
  
  METHODS
  Ten contact lens solutions, including one new system, were tested for their effectivities against cysts of three Acanthamoeba strains. Of main interest was an incubation time of 8 hours (overnight disinfection) and cyst quantities of 10 and 10, respectively.
  
  
  RESULTS
  Boston Advance (polyaminopropyl biguanide 0.0005%, chlorhexidine 0.003%) for the storage of rigid gas permeable contact lenses destroyed the cysts of all strains at either concentration within one hour of exposure. Meni Care Plus (polyhexamethylene biguanide 0.0005%) also destroyed 10 cysts of all strains, however, 10 cysts only of two strains within one hour; after an exposure time of 8 hours all cysts were killed. The disinfecting solutions for soft contact lenses did not kill 10 cysts of either strain after 8 hours of incubation time.
  
  
  CONCLUSIONS
  Two of the tested contact lens solutions (the ones for rigid gas permeable lenses) destroyed the cysts of all strains. One of these, containing a combination of two amoebicidal ingredients even after only one hour of exposure time.
authors: Department of Ophthalmology, University of Graz, Austria.
authors: Klaus
authors: K
authors: Hiti
authors: Julia
authors: J
authors: Walochnik
authors: Eva
authors: E
authors: Maria Haller-Schober
authors: Christoph
authors: C
authors: Faschinger
authors: Horst
authors: H
authors: Aspöck