Light-directed maskless synthesis of peptide arrays using photolabile amino acid monomers.
Novel photolabile amino acid monomers for photolithographic solid-phase peptide synthesis has been developed and a method for the maskless synthesis of individually addressable peptide microarrays using new building blocks has been described; these peptide microarrays are suitable for repetitive epitope-binding assays.
Bhushan
Kumar R
KR
Division of Hematology/Oncology, SL-B10, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA. kbhushan@bidmc.harvard.edu