title: A versatile access to new macrocyclic oligoheterocycles (MOH).
abstract: An efficient and straightforward methodology for the parallel solid-phase synthesis of a variety of new macrocyclic oligoheterocycles is described. Exhaustive reduction of resin-bound cyclic polyamides using borane generates polyamines. Treatment of separated pairs of amines with a variety of bifunctional reagents provides, following cleavage from the solid support, the desired macrocyclic oligoheterocyclic (MOH) compounds in good yields and purities.
authors: Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121, USA. adeln@tpims.org
authors: Adel
authors: A
authors: Nefzi
authors: Rodegar T
authors: RT
authors: Santos