title: Solid-phase synthesis of pyrazolopyridines from polymer-bound alkyne and azomethine imines.
abstract: Study was made of the 1,3-dipolar cycloaddition of polymer-bound alkynes to azomethine imines generated in situ from N-aminopyridine iodides. Aromatization of the cycloadducts gives polymer-bound pyrazolopyridines that can be released from the resin as carboxylic acids with trifluoroacetic acid or as methyl esters with sodium methoxide.
authors: Division of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Helsinki, Finland.
authors: Kirsi
authors: K
authors: Harju
authors: Irene
authors: I
authors: Kylänlahti
authors: Timo
authors: T
authors: Paananen
authors: Mika
authors: M
authors: Polamo
authors: John
authors: J
authors: Nielsen
authors: Jari
authors: J
authors: Yli-Kauhaluoma