title: [Univariate and multivariate regression analyses of recurrence and metastasis of colon cancer after radical resection].
abstract: OBJECTIVE
  The prognosis of colon cancer after radical resection has seldom been reported, and the results are different. This study aimed to investigate the clinicopathologic factors related to recurrence and metastasis of colon cancer after radical resection.
  
  
  METHODS
  The clinicopathologic and follow-up data of 152 patients with colon cancer, treated with radical resection from Jan. 1999 to Dec. 2000, were analyzed retrospectively.
  
  
  RESULTS
  The overall recurrence and metastasis rate was 19.74%, and the liver metastasis rate was 9.87%. Univariate analysis showed that blood transfusion, disease duration, tumor size, tumor movement, histological differentiation, Dukesostage, and lymph node involvement were correlated to recurrence and metastasis of colon cancer after operation; blood transfusion, serum concentration of carcinoembryonic antigen (CEA), tumor movement, histological differentiation, Dukesostage, and lymph node involvement were correlated to liver metastasis. Multivariate analysis showed that tumor movement, histological differentiation, and lymph node involvement were prognostic factors for recurrence and metastasis, while serum concentration of CEA, histological differentiation, and lymph node involvement were prognostic factors for liver metastasis.
  
  
  CONCLUSIONS
  Tumor movement, histological differentiation, and lymph node involvement are important prognostic factors for recurrence and metastasis of colon cancer after radical resection. Patients with high serum concentration of CEA, poor histological differentiation, and lymph node involvement have increased risk of liver metastasis.
authors: State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China.
authors: Jing-Qing
authors: JQ
authors: Ren
authors: Zhi-Wei
authors: ZW
authors: Zhou
authors: De-Sen
authors: DS
authors: Wan
authors: Zhen-Hai
authors: ZH
authors: Lu
authors: Gong
authors: G
authors: Chen
authors: Guo-Qiang
authors: GQ
authors: Wang
authors: Shao-Xian
authors: SX
authors: Tang
authors: Jun-Jiang
authors: JJ
authors: Wang