title: Surgical outcomes of spinal cord astrocytomas.
abstract: METHODS
  Retrospective case series.
  
  
  OBJECTIVE
  To analyze prognostic factors for patients with spinal cord astrocytomas.
  
  
  METHODS
  Department of Orthopaedic Surgery, Keio University, Japan.
  
  
  METHODS
  Seven patients received total excisions (group T), eight underwent partial excisions (group P), and 15 had excisional biopsies (group B). Impacts of the tumor histological grade, the level of the tumor, the types of surgical interventions, and the use of adjuvant radiotherapies on the survival and functional outcomes of 30 patients (18 in low-grade and 12 high-grade malignancy tumors) were analyzed.
  
  
  RESULTS
  The survival rate of the low-grade malignancy group was significantly higher than that of the high-grade group. The survival rate of the patients with thoracic astrocytomas was significantly higher than those with cervical astrocytomas. In both the low- and high-grade groups, the survival rates in groups P/T were significantly higher than those in group B. In the low-grade group, five patients, whose preoperative functional statuses were classified as 'fair' or better, remained 'fair' or better after surgery. In the high-grade group, the postoperative functional statuses were classified as 'no change' or 'aggravated' in all except two patients. No significant difference in the survival rates was detected between patients with and without adjuvant radiotherapy.
  
  
  CONCLUSIONS
  The tumor grade and the extent of tumor resection were significant prognostic factors for survival rate. In low-grade malignancy group, good motor function was retained when surgeries were performed before substantial neurological deterioration. The efficacy of postoperative radiotherapy has yet to be determined and needs further study.
authors: Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan.
authors: M
authors: M
authors: Nakamura
authors: K
authors: K
authors: Chiba
authors: K
authors: K
authors: Ishii
authors: Y
authors: Y
authors: Ogawa
authors: H
authors: H
authors: Takaishi
authors: M
authors: M
authors: Matsumoto
authors: Y
authors: Y
authors: Toyama