title: Aerobic physical fitness in relation to blood lipids and fasting glycaemia in adolescents: influence of weight status.
abstract: OBJECTIVE
  We explored the associations between aerobic physical fitness with blood lipids and a composite index of blood lipids and fasting glycaemia in adolescents, analysing possible interactions with weight status.
  
  
  RESULTS
  Body mass index and aerobic physical fitness was measured in 2090 adolescents (1034 males and 1056 females) 13-18.5 years by using the 20-m shuttle run test. Plasma glucose, total, high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol, triglycerides, apolipoprotein (apo) A-I, apo B-100 and lipoprotein(a) [Lp(a)] were measured in 460 of the 2090 subjects. After adjustment for confounding factors, a continuously distributed summary score for blood lipids and fasting glycaemia was significantly related to aerobic fitness in males (P=0.018) and females (P=0.045, from the 2nd to the 4th quartile of aerobic fitness). After adjustment for gender, age, sexual maturation and economic status, aerobic fitness was related to the composite index of blood lipids and glycaemia in both overweight and non-overweight adolescents (P< 0.05). However, for the same level of aerobic fitness, the composite index of blood lipids and glycaemia was significantly higher in overweight adolescents (P=0.001). After setting the minimal aerobic fitness standards to present a healthy lipid profile, about 50% of males did not reach such values.
  
  
  CONCLUSIONS
  Our data suggest that both aerobic fitness and weight management are associated with a composite index of blood lipids and glycaemia in adolescents. Our study also provides the minimal levels of aerobic physical fitness associated with a favourable lipid profile in male adolescents, a new tool which should be adopted by schools as "aerobic fitness standards".
authors: Department of Medical Physiology, School of Medicine, University of Granada, Granada 18071, Spain. jose.mesa@ems.rmit.edu.au
authors: José L
authors: JL
authors: Mesa
authors: Jonatan R
authors: JR
authors: Ruiz
authors: Francisco B
authors: FB
authors: Ortega
authors: Julia
authors: J
authors: Wärnberg
authors: Domingo
authors: D
authors: González-Lamuño
authors: Luis A
authors: LA
authors: Moreno
authors: Angel
authors: A
authors: Gutiérrez
authors: Manuel J
authors: MJ
authors: Castillo