Assessment of risk-independent follow-up to detect asymptomatic recurrence after curative resection of colorectal cancer.
OBJECTIVE
Colorectal cancer is one of the leading causes of cancer death. We analyzed the value of standardized, risk-independent postoperative surveillance.


METHODS
Between 1995 and 2001, 564 patients with colorectal cancer underwent standardized oncologic resection. One hundred thirty-four were unable to take part in the surveillance program, while 430 patients were grouped as follows: group I (n=272, risk-independent follow-up), group II (n=113, follow-up at other departments), and group III (n=45, no follow-up).


RESULTS
The 5-year cancer-specific survival rate for UICC III and IV was significantly higher in group I (87%) as compared to group II (35%). In group I, the 5-year disease-free survival rate was 70%. Cancer recurrence occurred at mean 17 (+/-12) months after colorectal resection and yielded a 5-year survival rate of 63%. Reresection was performed in 17 (35%) patients, of whom ten remained disease-free (5-year survival rate, 91%). The money spent for one patient's 5-year follow-up was 1665.


CONCLUSIONS
A standardized, risk-independent follow-up program allows early diagnosis of asymptomatic recurrence of colorectal cancer. Reresection improves the 5-year survival rate in this setting.
Zitt
Matthias
M
Department of General and Transplant Surgery, Innsbruck Medical University, Anichstrasse 35, 6020, Innsbruck, Austria.
Mühlmann
Gilbert
G
Weiss
Helmut
H
Kafka-Ritsch
Reinhold
R
Oberwalder
Michael
M
Kirchmayr
Werner
W
Margreiter
Raimund
R
Ofner
Dietmar
D
Klaus
Alexander
A