title: Chemical transformation of prostaglandin-A2: a novel series of C-10 halogenated, C-12 hydroxylated prostaglandin-A2 analogues.
abstract: [reaction: see text] Synthesis of a novel class of C-10 halogenated and C-12 oxygenated prostaglandin-A(2) derivatives (6a-6c) has been accomplished. (15S)-Prostaglandin-A(2) (1), from the gorgonian Plexaura homomalla, served as the starting material for the synthesis. The absolute configuration was determined using NMR.
authors: Department of Medicinal Chemistry, University of Utah, Salt Lake City, 84112, USA.
authors: Anokha S
authors: AS
authors: Ratnayake
authors: Tim S
authors: TS
authors: Bugni
authors: Charles A
authors: CA
authors: Veltri
authors: Jack J
authors: JJ
authors: Skalicky
authors: Chris M
authors: CM
authors: Ireland