A method classifying biologics for formulary decision making.
Pharmacy and Therapeutics Committees have been trying to determine the correct way to incorporate biologic agents into their formularies. As with any new drug, the first step is to determine the appropriate category or classification in which they will be evaluated. The biologics present some challenges to classification in significant ways. Even though two or more biologics may have a common indication, their differences in mechanism of action, method of delivery, dosing schedule, and other factors may be important considerations in choice of a useful classification. A method is suggested and illustrated, utilizing the group of biologic agents commonly used to treat psoriasis (including, for illustrative purposes, alefacept, efalizumab, etanercept, and infliximab).
Broder
Michael S
MS
Partnership Health Analytic Research, LLC, Los Angeles , California 90025, USA. mbroder@pharllc.com
Reissman
Debi
D