5-Aminolevulinate Synthesis in Permeabilized Filaments of the Blue-Green Alga Anabaena variabilis.
Filaments of the blue-green alga Anabaena variabilis permeabilized by dimethylsulfoxide (DMSO) produce increased amounts of 5-aminolevulinate in the presence of levulinic acid. The metabolic activity of the filaments remains unperturbed in the presence of up to 7.5% (v/v) DMSO. Studies utilizing DMSO-permeabilized filaments confirm that 5-aminolevulinate is synthesized preferably from glutamate and, to a lesser extent, from alpha-ketoglutarate in this organism.
Avissar
Y J
YJ
Department of Applied Hydrobiology, Desert Research Institute, Ben Gurion University of the Negev, Beer Sheva, 84120, Israel.