Translating the concept of suppressor/regulatory T cells to clinical applications.
The in vivo expansion of suppressor/regulatory T cells (Tregs) is a desirable event in autoimmunity and transplantation. Here we summarize the general rules involved in antigen recognition by T cells and describe Tregs and their requirements, discussing different levels of immune intervention.
Franco
Alessandra
A
Department of Medicine and Pediatrics, University of California, San Diego, La Jolla, California 92093-0731, USA.
Albani
Salvatore
S