title: Direct synthesis of bipyrroles using phenyliodine bis(trifluoroacetate) with bromotrimethylsilane.
abstract: [reaction: see text] The hypervalent iodine(III) reagent, phenyliodine bis(trifluoroacetate) (PIFA), mediates the unprecedented, oxidative coupling reaction of pyrroles to give alpha-linked bipyrroles selectively in the presence of bromotrimethylsilane. This straightforward synthesis could provide 2,3'-bipyrrole by the choice of a N-substituent of pyrrole. Mechanistic consideration of the present reaction is also described.
authors: Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.
authors: Toshifumi
authors: T
authors: Dohi
authors: Koji
authors: K
authors: Morimoto
authors: Akinobu
authors: A
authors: Maruyama
authors: Yasuyuki
authors: Y
authors: Kita