Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.
The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family.
Holmes
Margaret A
MA
Structural Genomics of Pathogenic Protozoa (SGPP) Consortium, USA.
Buckner
Frederick S
FS
Van Voorhis
Wesley C
WC
Verlinde
Christophe L M J
CL
Mehlin
Christopher
C
Boni
Erica
E
DeTitta
George
G
Luft
Joseph
J
Lauricella
Angela
A
Anderson
Lori
L
Kalyuzhniy
Oleksandr
O
Zucker
Frank
F
Schoenfeld
Lori W
LW
Earnest
Thomas N
TN
Hol
Wim G J
WG
Merritt
Ethan A
EA