title: De novo calcification of liver and nodal metastases in prostate carcinoma.
abstract: Prostate cancer has a distinctly recognized pattern of metastases: multifocal and osteoblastic lesions involving the axial skeleton and non-calcified lymph nodes in the pelvic and lumbar aortic groups. Most adenocarcinomas are capable of producing macrocalcification. We report a case of prostate cancer with de novo calcified metastases to the liver and retroperitoneal lymph nodes mimicking the pattern usually seen in mucin-producing adenocarcinomas arising from the gastrointestinal tract. To our knowledge, this is the first such case to be reported in the literature. We propose a multifactorial mechanism that supports dystrophic calcification in this case. The knowledge of atypical presentation of metastatic disease can prevent diagnostic delay and prompt initiation of therapy.
authors: Department of Internal Medicine, University of California, San Diego, San Diego, CA 92161, USA.
authors: P
authors: P
authors: Ghosh
authors: A C
authors: AC
authors: Santosa
authors: G Y
authors: GY
authors: Lin
authors: T M
authors: TM
authors: Downs