title: High-dose therapy and autologous stem cell transplantation for children with HIV-associated non-Hodgkin lymphoma.
abstract: In contrast to adults, autologous stem cell transplantation (ASCT) as part of the salvage strategy after high-dose chemo/radiotherapy in human immunodeficiency virus (HIV) related Non-Hodgkin lymphoma (NHL) is not yet established for children. We report on a 13-year patient with congenital HIV infection and refractory Burkitt lymphoma, who was successfully treated by high-dose therapy (HDT) including rituximab followed by ASCT. After 26 months follow-up the patient remains in complete remission and his HIV parameters have normalized with continued highly active antiretroviral therapy (HAART). HIV infection may no longer exclude children from ASCT as part of salvage therapy.
authors: Department of Pediatric Hematology/Oncology, University Children's Hospital, Bern, Switzerland. simon.fluri@insel.ch
authors: Simon
authors: S
authors: Fluri
authors: Roland
authors: R
authors: Ammann
authors: Annette Ridolfi
authors: AR
authors: Lüthy
authors: Andreas
authors: A
authors: Hirt
authors: Christoph
authors: C
authors: Aebi
authors: Andrea
authors: A
authors: Duppenthaler
authors: Kurt
authors: K
authors: Leibundgut