title: Lectin binding to mouse blood lymphocytes during tumor growth.
abstract: Binding of FITC-labeled lectins to lymphocytes from intact mice and mice with transplanted Ehrlich carcinoma and CaO-1 ovarian carcinoma was studied by flow cytofluorometry. Specific binding of lectins by mannose and N-acetylgalactosamine was demonstrated. Lectin binding to lymphocytes from animals with tumors decreased by more than 50% in comparison with intact animals. Changed protein glycosylation during tumor growth is specific and differs for tumors of different origin.
authors: N. N. Blokhin National Oncological Research Center, Russian Academy of Medical Sciences, Moscow.
authors: S M
authors: SM
authors: Sitdikova
authors: B S
authors: BS
authors: Amandzholov
authors: M V
authors: MV
authors: Kiselevskii
authors: F V
authors: FV
authors: Donenko