title: Effect of 80 mg/day simvastatin therapy on cardiovascular outcomes in adults with versus without metabolic syndrome.
abstract: It is not known whether high-dose statins can reduce the excess burden (and consequent adverse cardiovascular outcomes) of coronary artery disease in patients with metabolic syndrome compared with those without metabolic syndrome. The results of our study suggest that high-dose simvastatin may be required to reduce excess events in very high-risk cohorts with metabolic syndrome.
authors: Indiana University School of Medicine and affiliated Veterans Affairs Medical Center, Indianapolis, Indiana, USA. Masoor.kamalesh@med.Va.gov
authors: Masoor
authors: M
authors: Kamalesh
authors: Roopa
authors: R
authors: Rao
authors: Stephen
authors: S
authors: Sawada
authors: Amy
authors: A
authors: Friend
authors: Ellen
authors: E
authors: Schellhase
authors: Tamara
authors: T
authors: Evans