title: Risk factor analysis for metaplastic gastritis in Koreans.
abstract: OBJECTIVE
  To conduct a retrospective study to determine the risk factors for development of metaplastic gastritis in Korean population.
  
  
  METHODS
  The database of 113449 subjects who underwent a gastroscopy for the purpose of a regular check-up at center for health promotion, Samsung medical center during 5 years was collected and retrospectively analyzed. Among them, 5847 subjects who had endoscopically diagnosed as a metaplastic gastritis or 10076 normal as well as answered to questionnaire were included for present study. The subjects were divided into 2 groups; Group I, normal and Group II, metaplastic gastritis. Age, gender, Helicobacter pylori (H pylori) seropositivity, body mass index (BMI), family history of cancer, smoking, alcohol consumption, total daily calories, folate and salt intake and dietary habit (out-eating, overeating, irregular eating) were retrieved from questionnaire or electronic medical record and compared between group I and group II.
  
  
  RESULTS
  The prevalence of group II was 11% (13578/113449) increasing its prevalence with age (P = 0.000). But, there was no significant association between 2 groups in BMI, family history of cancer, alcohol consumption, total daily calories, folate and salt intake and dietary habit (out-eating, overeating, irregular eating). Old age (P=0.000), male gender (P = 0.000), H pylori seropositivity (P = 0.010) and current smoker (P = 0.000) were significantly more common in group II at multiple logistic regression model.
  
  
  CONCLUSIONS
  Our data suggested that old age, male gender, H pylori seropositivity and smoking were risk factors for metaplastic gastritis, precancerous lesion of gastric cancer.
authors: Center for Health Promotion, Samsung Medical Center, Seoul, Korea.
authors: Soonami
authors: S
authors: Choi
authors: Yun Jeong
authors: YJ
authors: Lim
authors: Sue Kyung
authors: SK
authors: Park