[Progress in the research of germ cell from human embryonic stem cells].
As the development of spontaneous differentiation of germ cells and gametogenesis from mouse embryonic stem cells (mES) in vitro, hES (human embryonic stem cells) also have potential to differentiated into germ cells in theory. This review focuses on the stem cells niches and genes regulating the hES differentiation toward germ cells, as well as the recent advance and application on the reproductive medicine and therapy of infertility.
Guo
Xin
X
Laboratory of Male Reproductive Medicine, Shenzhen Hospital of Peking University, Shenzhen 518036, China.
Cai
Zhi-Ming
ZM
Gui
Yao-Ting
YT