Corticosteroid replacement in critically ill patients.
This review addresses the use of corticosteroid replacement in critically ill patients. Low-dose corticosteroid replacement for critically ill patients with septic shock has been shown to reduce the duration of vasopressor-dependent shock, to shorten ICU length of stay, and, in recent trials, to reduce mortality. Numerous questions remain to be fully answered about patient selection, corticotropin-stimulation testing methods, and interpretation of results.
Jacobi
Judith
J
Pharmacy Department Methodist Hospital/Clarian Health Partners, AG401, 1701 North Senate Boulevard, Indianapolis, IN 46202, USA. jjacobi@clarian.org