title: Use of an acute seroconversion panel to evaluate a third-generation enzyme-linked immunoassay for detection of human immunodeficiency virus-specific antibodies relative to multiple other assays.
abstract: A human immunodeficiency virus type 1 (HIV-1)/HIV-2 antibody screening assay, the Genetic Systems HIV-1/HIV-2 PLUS O EIA, was compared to several established screening or confirmatory tests using an acute HIV seroconversion panel. The HIV-1/HIV-2 PLUS O EIA showed an improved sensitivity over all tested antibody screening methods, and detected antibody in 7 of 19 specimens found to be negative by a first-generation EIA but positive for the presence of HIV RNA.
authors: San Francisco Department of Public Health, 101 Grove St., Rm. 412, San Francisco, CA 94102, USA. brian.louie@sfdph.org
authors: Brian
authors: B
authors: Louie
authors: Mark W
authors: MW
authors: Pandori
authors: Ernest
authors: E
authors: Wong
authors: Jeffrey D
authors: JD
authors: Klausner
authors: Sally
authors: S
authors: Liska