[An in vitro experiment on the antimicrobial effects of ethanol extract from salvia miltiorrhiza bunge on several oral pathogenic microbes].
OBJECTIVE
To study the in vitro antimicrobial activity of ethanol extract of salvia miltiorrhiza bunge on several oral pathogenic microbes.


METHODS
Antimicrobial activities of ethanol extract of salvia miltiorrhiza bunge for porphyromonas gingivalis ATCC 33277, A. actinomycetes comitans ATCC 24523, Streptococcus mutans, and Lactobacillus were determined using the cup-plate method. The minimum antibacterial concentrations of ethanol extract of salvia miltiorrhiza bunge were measured. SPSS10.0 software package was used for Student's t test.


RESULTS
Ethanol extract of salvia miltiorrhiza bunge had antimicrobial activities on Porphyromonas gingivalis, A. actinomycetemcomitans, Streptococcus mutans, Lactobacillus, and the minimum inhibitory concentrations were 15.62 mg/ml, 15.62 mg/ml, 62.50mg/ml and 15.62 mg/ml; The pH of the solution was influential to its antimicrobial activity.


CONCLUSIONS
Ethanol extract of salvia miltiorrhiza bunge has an antimicrobial activity on oral pathogenic microbes.
Deng
Jing
J
Department of Stomatology, The Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, Shandong Province, China. dengjing3333@yahoo.com.cn
Zhang
Dai-zun
DZ
Yang
Wen-jing
WJ