Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins.
The endothelins are a family of hormones that have a biphasic action on pituitary lactotrophs. The initial effect is stimulatory, followed later by inhibition that persists long after the agonist has been removed. Recent research has uncovered several G protein pathways that mediate these effects.
Bertram
Richard
R
Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA. bertram@math.fsu.edu
Tabak
Joel
J
Toporikova
Natalia
N
Freeman
Marc E
ME