Parkinsonism in Caplan's syndrome.
Parkinsonism is a rare feature of immunological diseases. We describe a 67-year-old man with Caplan's syndrome (CS) and parkinsonism. CS is an immunologic disease characterised by the presence of rheumatoid arthritis associated with a specific form of pneumoconiosis. Parkinsonism as a manifestation of involvement of the central nervous system in this condition has never been reported. Following immunosuppressive treatment both the CS and the parkinsonian signs and symptoms showed a marked improvement. The role of immune mechanisms in these parkinsonian syndromes is discussed.
Rizzo
G
G
Department of Neurological Sciences, University of Bologna, Via Ugo Foscolo 7, I-40123 Bologna, Italy.
Scaglione
C
C
Lopane
G
G
Pollini
A
A
Tommasoni
E
E
Martinelli
P
P