[Intralesional injection of Pingyangmycin for treatment of venous-venular malformation in the maxillofacial regions of children: report of 306 cases].
OBJECTIVE
To evaluate the effect of intralesional injection of Pingyangmycin (PYM) for treatment of venous-venular malformation in the maxillofacial regions of children.


METHODS
The medical records of 306 patients with venous-venular malformation in the maxillofacial regions between January 1997 and June 2005 were reviewed. One hundred and twenty-three of the patients were men, and one hundred and eighty-three were woman, the sex ratio was 1:1.49. The patients aged from one month to 12 years, 172 were less than 6 months (56.21%). Pingyangmycin was injected into the center or in the vicinity of the venous-venular malformations, and repeated every 7 to 10 days. This cycle were repeated 3 to 5 times when necessary.


RESULTS
Three hundred and six patients were followed up for 6 to 102 months. Complete response was obtained in 156 cases (50.98%), partial response in 116 cases (37.91%), and improvement in 34 cases (11.11%). The overall response rate was 100%, and the curative rate was 88.89%.


CONCLUSIONS
This method is safe, simple and effective for venous-venular malformation in the maxillofacial regions of children.
Shou
Bo-quan
BQ
Department of Stomatology, Nanjing General Hospital of PLA, Nanjing 210002, Jiangsu Province, China. shoujiajun10@sina.com
Shou
Wei-dong
WD
Yang
Zhen
Z
Meng
Zhao-ye
ZY
Zhang
Sen-lin
SL
Cao
Gang
G
Dong
Zhen
Z