Shape-selective fluorescent sensing ensemble using a tweezer-type metalloreceptor.
[reaction: see text] A fluorescent sensing ensemble for pyridine-derived compounds is described. The receptor portion of the ensemble is prepared from a bisimidazole pyridine which coordinates copper to form a well-defined cavity. Small heteroaromatic guests such as adenine bind strongly in the cavity. The fluorescent response is provided by a dye which is coordinated to the receptor and quenched by the metal ion. The dye is released upon guest binding providing up to 25-fold fluorescence increases.
Plante
Jeffrey P
JP
Department of Chemistry, University of Missouri-Columbia, 65211, USA.
Glass
Timothy E
TE