title: The effect of the administration of human gamma globulins in a model of BCG infection in mice.
abstract: The effect of the administration of a commercial preparation of human gamma globulins has been evaluated in a mouse model of intranasal infection with BCG. First, we demonstrated the passage of specific antibodies to saliva and lung lavage following the intranasal or intraperitoneal administration to mice of human gamma globulins. This treatment of mice inhibited BCG colonization of the lungs (p < 0.01). A similar inhibitory effect was observed after infection of mice with gamma globulin opsonized BCG organisms (p < 0.01). These results are relevant for the development of new strategies for the control and treatment of tuberculosis.
authors: Department of Molecular Biology, Finlay Institute, La Lisa, Havana City, Cuba.
authors: Nesty
authors: N
authors: Olivares
authors: Annette
authors: A
authors: León
authors: Yamilé
authors: Y
authors: López
authors: Alina
authors: A
authors: Puig
authors: Armando
authors: A
authors: Cádiz
authors: Gustavo
authors: G
authors: Falero
authors: Máximo
authors: M
authors: Martínez
authors: Marie E
authors: ME
authors: Sarmiento
authors: Mildrey
authors: M
authors: Fariñas
authors: Juan F
authors: JF
authors: Infante
authors: Gustavo
authors: G
authors: Sierra
authors: Rosa L
authors: RL
authors: Solís
authors: Armando
authors: A
authors: Acosta