Some considerations on the use of peptides and mRNA for therapeutic vaccination against cancer.
Active immunization against existing cancer is a field that is currently in development and is associated with a number of problems. The potential use of peptides as minimal essential T-cell antigens and of mRNA as a novel form of antigen with advantages is discussed, with special consideration of practical aspects.
Rammensee
Hans-Georg
HG
Interfakultäres Institut für Zellbiologie, Abteilung Immunologie, Eberhard Karls Universität, Tübingen, Germany. rammensee@uni-tuebingen.de