Fast orientation mapping from HARDI.
This paper introduces a new, accurate and fast method for fiber orientation mapping using high angular resolution diffusion imaging (HARDI) data. The approach utilizes the Fourier relationship between the water displacement probabilities and diffusion attenuated magnetic resonance (MR) signal expressed in spherical coordinates. The Laplace series coefficients of the water displacement probabilities are evaluated at a fixed distance away from the origin. The computations take under one minute for most three-dimensional datasets. We present orientation maps computed from excised rat optic chiasm, brain and spinal cord images. The developed method will improve the reliability of tractography schemes and make it possible to correctly identify the neural connections between functionally connected regions of the nervous system.
Ozarslan
Evren
E
Department of Computer and Information Science and Engineering, University of Florida, P.O. Box 116120, Gainesville, FL 32611, USA. evren@cise.ufl.edu
Shepherd
Timothy M
TM
Vemuri
Baba C
BC
Blackband
Stephen J
SJ
Mareci
Thomas H
TH