Small-molecule microarrays: development of novel linkers and an efficient detection method for bound proteins.
Novel isocyanate and diazoketone linkers possessing polyoxypropylenediamine as a spacer for small-molecule microrray are developed. White light interferometry is introduced to detect bound proteins on the glass slides without using chemically modified proteins.
Kurosu
Michio
M
Department of Microbiology, Immunology, and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, 80523-1682, USA. mkurosu@lamar.colostate.edu
Mowers
Williams A
WA