title: Catabolism of 5-Aminolevulinic Acid to CO(2) by Etiolated Barley Leaves.
abstract: The in vivo oxidation of the C(4) and C(5) of 5-aminolevulinic acid (ALA) to CO(2) has been studied in etiolated barley (Hordeum vulgare L. var. Larker) leaves in darkness. The rate of (14)CO(2) evolution from leaves fed [4-(14)C]ALA is strongly inhibited by aminooxyacetate, anaerobiosis, and malonate. The rate of (14)CO(2) evolution from leaves fed [5-(14)C]ALA is also inhibited by these treatments but to a lesser extent. These results suggest that (a) one step in ALA catabolism is a transamination reaction and (b) the C(4) is oxidized to CO(2) via the tricarboxylic acid cycle to a greater extent than is the C(5).
authors: Department of Biological Sciences, University of Illinois at Chicago Circle, Chicago, Illinois 60680.
authors: J X
authors: JX
authors: Duggan
authors: E
authors: E
authors: Meller
authors: M L
authors: ML
authors: Gassman