Microwave-assisted, boron trichloride mediated acylation of phenols-synthesis of (o-hydroxyaryl)(aryl)methanones and xanthones.
A novel and efficient microwave-assisted, BCl(3) mediated coupling reaction to synthesize o-(hydroxyaryl)(aryl)methanone structures from phenols and acyl chlorides is described. This reaction was further incorporated into a two-step synthesis of biologically interesting xanthones.
Zhang
Lei
L
CytRx laboratories, Inc., Worcester, Massachusetts 01605, USA.
Zhang
John Y
JY