The oxanorbornene approach to 3-hydroxy, 3,4-dihydroxy and 3,4,5-trihydroxy derivatives of 2-aminocyclohexanecarboxylic acid.
The nitro oxanorbornene adduct derived from the Diels-Alder reaction of ethyl (E)-3-nitroacrylate and furan provides a versatile template for the stereoselective synthesis of hydroxylated derivatives of 2-aminocyclohexanecarboxylic acid (ACHC).
Masesane
Ishmael B
IB
Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK. masesane@mopipi.ub.bw
Batsanov
Andrei S
AS
Howard
Judith A K
JA
Mondal
Raju
R
Steel
Patrick G
PG