title: First case of ivermectin-induced severe hepatitis.
abstract: Loiasis, caused by the filarial parasite Loa loa, is endemic in West and Central Africa. Ivermectin has been shown to be an effective treatment of loiasis. We report the case of a 20-year-old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis, identified 1 month after a single dose of ivermectin. Liver biopsy showed intralobular inflammatory infiltrates, confluent necrosis and apoptosis, compatible with drug-induced liver disease. To our knowledge, this is the first case of ivermectin-induced severe liver disease published in the literature.
authors: Swiss Tropical Institute, Medical Department, Socinstrasse 57, 4002 Basle, Switzerland. oviet@yahoo.com
authors: Olivia
authors: O
authors: Veit
authors: Bernhard
authors: B
authors: Beck
authors: Michael
authors: M
authors: Steuerwald
authors: Christoph
authors: C
authors: Hatz