title: Proteomic analysis of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of retinoblastoma-interacting-zinc-finger protein.
abstract: To identify a growth-promoting activity related to retinoblastoma-interacting-zinc-finger (RIZ) protein, differential protein expression of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of RIZ protein was analyzed by a robust bottom-up mass-spectrometry proteomic approach. Spots corresponding to qualitative and quantitative differences in protein expression have been selected and identified. Some of these proteins have been previously reported as being associated with different types of carcinomas or involved in cell proliferation and differentiation. Knowledge of specific differentially expressed proteins by MCF-7-derived cell lines expressing RIZ different domains will provide the basis for identifying a growth-promoting activity related to RIZ gene products.
authors: Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, I-81100 Caserta, Italy.
authors: Angela
authors: A
authors: Chambery
authors: Annarita
authors: A
authors: Farina
authors: Antimo
authors: A
authors: Di Maro
authors: Mariangela
authors: M
authors: Rossi
authors: Ciro
authors: C
authors: Abbondanza
authors: Bruno
authors: B
authors: Moncharmont
authors: Livia
authors: L
authors: Malorni
authors: Giuseppina
authors: G
authors: Cacace
authors: Gabriella
authors: G
authors: Pocsfalvi
authors: Antonio
authors: A
authors: Malorni
authors: Augusto
authors: A
authors: Parente