title: Human immunodeficiency virus-associated disorders in Pakistan.
abstract: We have documented evidence of the human immunodeficiency virus (HIV) infection in four individuals including a blood donor and three members of a family (husband, wife, and a child) in Karachi, Pakistan. Our data indicate that HIV has been transmitted to the wife of the seropositive male, a drug abuser, in the recent past and that she has passed the virus to her newborn child perinatally/ transplacentally. The two seropositive males (blood donor and drug abuser) were diagnosed clinically as having persistent generalized lymphadenopathy, an AIDS-related condition (ARC), and the child presented with developmental disorders and neurologic manifestations. This is the first report of AIDS/ARC cases from Pakistan that can be directly related to HIV infection and its heterosexual transmission.
authors: Basic Medical Sciences Institute, Department of Microbiology, Jinnah Postgraduate Medical Center, Karachi, Pakistan.
authors: Rafiq M
authors: RM
authors: Khanani
authors: Amtul
authors: A
authors: Hafeez
authors: S M
authors: SM
authors: Rab
authors: Suraiya
authors: S
authors: Rasheed