Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica.
Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin.
Weber
Christian
C
Unité Biologie Cellulaire du Parasitisme, INSERM 786, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex 15, France.
Guigon
Ghislaine
G
Bouchier
Christiane
C
Frangeul
Lionel
L
Moreira
Sandrine
S
Sismeiro
Odile
O
Gouyette
Catherine
C
Mirelman
David
D
Coppee
Jean Yves
JY
Guillén
Nancy
N