title: A case of protein-losing enteropathy treated with methotrexate in a dog.
abstract: A 9-year-old female Pug was presented to us with chronic diarrhea. Hematologic findings indicated severe hypoproteinemia and hypoalbuminemia, and endoscopy revealed severe edema of the duodenal mucosa. Based on these results and on additional histopathological findings, we made a diagnosis of protein-losing enteropathy caused by lymphocytic-plasmacytic enteritis with lymphangiectasia. The dog was initially treated with prednisolone and cyclosporine. This treatment regimen was not effective. However, when methotrexate was substituted for cyclosporine, progress was obtained and the diagnosis was confirmed.
authors: Yuki Animal Hospital, Nagoya, Aichi, Japan.
authors: Masashi
authors: M
authors: Yuki
authors: Noriko
authors: N
authors: Sugimoto
authors: Kuniaki
authors: K
authors: Takahashi
authors: Hiromi
authors: H
authors: Otsuka
authors: Naohito
authors: N
authors: Nishii
authors: Kiyomi
authors: K
authors: Suzuki
authors: Tetsushi
authors: T
authors: Yamagami
authors: Hiroshi
authors: H
authors: Ito