Cross metathesis with strained exocyclic enones: synthesis of 3-alkylideneoxetan-2-ones from 3-methyleneoxetan-2-ones.
[reaction: see text] 3-Alkylideneoxetan-2-ones have been prepared in good to excellent yields with high Z-selectivity by olefin cross metathesis with 3-methyleneoxetan-2-ones in the presence of second generation metathesis catalysts 1 or 2.
Raju
Ravinder
R
Department of Chemistry, University of Connecticut, Storrs, 06269-3060, USA.
Howell
Amy R
AR