Spontaneous resolution of 2,3-bis-fluoren-9-ylidenesuccinic acid induced by achiral guest inclusion.
The racemic title host compound (1) formed homochiral inclusion crystals (conglomerate) of 1 with acetone, while heterochiral inclusion crystals (racemate) were obtained when complexed with ethyl acetate. Upon treatment of the homochiral inclusion crystals of 1 with gaseous acetyl chloride in the solid state, optically active 2,3-bis(fluorenylidene)succinic anhydride (3) was obtained in high optical purity.
Tanaka
Koichi
K
Department of Applied Chemistry, Faculty of Engineering & High Technology Research Center, Kansai University, Suita, Osaka, Japan. ktanaka@ipcku.kansai-u.ac.jp
Iwamoto
Toshimasa
T
Wada
Shin-Ichi
S
Frelek
Jadwiga
J
Caira
Mino R
MR