Effects of fructose 2,6-bisphosphate on phosphoglucomutase from plants.
Fructose 2,6-bisphosphate affects phosphoglucomutase from plant and animal sources in a similar way. As previously found with rabbit muscle phosphoglucomutase, fructose 2,6-bisphosphate cannot substitute for glucose 1,6-bisphosphate as a cofactor in the reaction catalyzed by phosphoglucomutase from potato tubers, pea seeds, and string-beans. In the presence of glucose 1,6-bisphosphate, fructose 2,6-bisphosphate inhibits phosphoglucomutase from potato tubers. Activation of phosphoglucomutase from plant sources by fructose 2,6-bisphosphate reported by others was probably due to contamination of the commercial preparation of fructose 2,6-bisphosphate by glucose 1,6-bisphosphate.
Carreras
M
M
Department de Bioquimica, Facultat de Medicina, Universitat de Barcelona, Casanova 143, 08036-Barcelona, Spain.
Bartrons
R
R
Climent
F
F
Carreras
J
J