title: Liver involvement in Langerhans' cell histiocytosis. Case report.
abstract: Langerhans'cell histiocytosis (Histiocytosis X) is a rare disease of unknown cause characterized by oligoclonal proliferation of Langerhans cells. It occurs mostly in children and young adults and involves one or more body systems such as bone, hypothalamus, posterior pituitary gland, lymph nodes, liver or various soft tissues. The diagnosis is always made by a histological approach. We report a case of Langerhans'cell histiocytosis in a young patient with clinical signs of diabetes insipidus and hepatic involvement in whom the immunohistochemical analysis of the liver tissue led to the definitive diagnosis.
authors: Medical Clinic, Sf. Ioan Hospital, Bucharest, Romania. endo_din@yahoo.com
authors: Ion
authors: I
authors: Dina
authors: Catalin
authors: C
authors: Copaescu
authors: Vlad
authors: V
authors: Herlea
authors: Fritz
authors: F
authors: Wrba
authors: Claudia
authors: C
authors: Iacobescu