title: [A case of hepatitis and pneumonitis caused by Bofutsusyo-san herbal medicine].
abstract: We report a case of drug-induced pneumonitis and hepatitis associated with the herbal medication Bofutsusyo-san. A 41-year-old woman was admitted to our hospital with pneumonitis and hepatitis. She complained of fever and dyspnea. Fine crackles were heard on chest auscultation and a chest X-ray film revealed diffuse reticulo-nodular shadow in both lung fields. Cessation of the medication improved the patient' s clinical and X-ray findings. Bronchoalveolar lavage showed an increase of the lymphocytes and a diminished CD4/CD8 ratio. A drug-induced lymphocyte stimulation test was positive. Challenge tests for Bofutsusyo-san were positive. A diagnosis of drug-induced pneumonitis and hepatitis was made. Our findings suggested an association with Ou-gon.
authors: Department of Respiratory Medicine, Ohashi Medical Center, Toho University.
authors: Nobuyuki
authors: N
authors: Hatanaka
authors: Toru
authors: T
authors: Yamagishi
authors: Hirotaka
authors: H
authors: Kamemura
authors: Ichiro
authors: I
authors: Nakazawa
authors: Yusuke
authors: Y
authors: Hirano
authors: Kimio
authors: K
authors: Hosaka
authors: Ken
authors: K
authors: Sanno
authors: Kei
authors: K
authors: Takahashi