Transmission of extramembrane conformational change into current: construction of metal-gated ion channel.
Interaction with Fe(III) induces the reversible conformational switch of the extramembrane segment in the artificial receptor channel, which is transmitted into membranes as an increase in channel current (ion flux).
Kiwada
Tatsuto
T
Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.
Sonomura
Kazuhiro
K
Sugiura
Yukio
Y
Asami
Koji
K
Futaki
Shiroh
S