title: Cardiac 123I-MIBG scintigraphy in patients with essential tremor.
abstract: In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.
authors: Department of Neurology, Ajou University School of Medicine, Suwon, South Korea. phisland@chol.com
authors: Phil Hyu
authors: PH
authors: Lee
authors: Ji Won
authors: JW
authors: Kim
authors: Oh Young
authors: OY
authors: Bang
authors: In Soo
authors: IS
authors: Joo
authors: Seok-Nam
authors: SN
authors: Yoon
authors: Kyoon
authors: K
authors: Huh