Fructose 2,6-bisphosphate inhibition of phosphoglucomutase.
Fructose 2,6-bisphosphate inhibits phosphoglucomutase noncompetitively with respect to the cofactor glucose 1,6-bisphosphate. Previous studies from our laboratory had shown that phosphoglucomutase was activated by fructose 2,6-bisphosphate in the absence of added glucose 1,6-bisphosphate. The fructose 2,6-bisphosphate activation previously reported was due to the presence of glucose 1,6-bisphosphate in the commercial preparation of fructose 2,6-bisphosphate.
Galloway
C M
CM
Department of Botany and Plant Sciences, University of California, Riverside, California 92521.
Dugger
W M
WM
Black
C C
CC