title: Palladium asymmetric allylic alkylation of prochiral nucleophiles: horsfiline.
abstract: [reaction; see text] The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.
authors: Department of Chemistry, Stanford University, California 94305, USA. bmtrost@stanford.edu
authors: Barry M
authors: BM
authors: Trost
authors: Megan K
authors: MK
authors: Brennan