Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: a single operator study.
OBJECTIVE
To accurately differentiate the adenomatous from the non-adenomatous polyps by colonoscopy.


METHODS
All lesions detected by colonoscopy were first diagnosed using the conventional view followed by chromoendoscopy with magnification. The diagnosis at each step was recorded consecutively. All polyps were completely removed endoscopically for histological evaluation. The accuracy rate of each type of endoscopic diagnosis was evaluated, using histological findings as gold standard.


RESULTS
A total of 240 lesions were identified, of which 158 (65.8%) were non-neoplastic and 82 (34.2%) were adenomatous. The overall diagnostic accuracy of conventional view, and chromoendoscopy with magnification was 76.3% (183/240) and 95.4% (229/240), respectively (P<0.001).


CONCLUSIONS
The combination of colonoscopy and magnified chromoendoscopy is the most reliable non-biopsy method for distinguishing the non-neoplastic from the neoplastic lesions.
De Palma
Giovanni-D
GD
DUN Chirurgia Generale e Tecnologie Avanzate, AOU Federico II, Facolta di Medicina e Chirurgia, Via Pansini, 5, 80131 Napoli, Italy. giovanni.depalma@unina.it
Rega
Maria
M
Masone
Stefania
S
Persico
Marcello
M
Siciliano
Saverio
S
Addeo
Pietro
P
Persico
Giovanni
G