title: Perception of emotional facial expressions at different intensities in early-symptomatic Huntington's disease.
abstract: BACKGROUND
  While there is abundant evidence that patients with Huntington's disease (HD) have an impairment in the recognition of the emotional facial expression of disgust, previous studies have only examined emotion perception using full-blown facial expressions.
  
  
  OBJECTIVE
  The current study examines the perception of facial emotional expressions in HD at different levels of intensity to investigate whether more subtle deficits can be detected, possible also in other emotions.
  
  
  METHODS
  We compared early symptomatic HD patients with healthy matched controls on emotion perception, presenting short video clips of a neutral face changing into one of the six basic emotions (happiness, anger, fear, surprise, disgust and sadness) with increasing intensity. Overall face perception ability as well as depressive symptoms were taken into account.
  
  
  RESULTS
  A specific impairment in recognizing the emotions disgust and anger was found, which was present even at low emotion intensities.
  
  
  CONCLUSIONS
  These results extend previous findings and support the use of more sensitive emotion perception paradigms, which enable the detection of subtle neurobehavioral deficits even in the pre- and early symptomatic stages of the disease.
authors: Psychological Laboratory, Helmholtz Instituut, Utrecht University, The Netherlands.
authors: Barbara
authors: B
authors: Montagne
authors: Roy P C
authors: RP
authors: Kessels
authors: Marjolein P M
authors: MP
authors: Kammers
authors: Elselijn
authors: E
authors: Kingma
authors: Edward H F
authors: EH
authors: de Haan
authors: Raymund A C
authors: RA
authors: Roos
authors: Huub A M
authors: HA
authors: Middelkoop