title: A prospective long-term study on the effects of rapid maxillary expansion in the early mixed dentition.
abstract: BACKGROUND
  The aim of this prospective longitudinal clinical study was to evaluate the short-term and long-term changes in dental-arch dimensions in patients treated with the acrylic splint rapid maxillary expander in the early mixed dentition followed by fixed appliances in the permanent dentition.
  
  
  METHODS
  The dental casts of 51 consecutively treated patients (TG) were compared with those of 26 untreated controls (CG) at 3 different times: pretreatment (T1), after expansion and fixed appliance therapy (T2), and at long-term observation (T3). The mean ages for the TG were 8 years 10 months at T1, 13 years 10 months at T2, and 19 years 9 months at T3. Arch widths, arch depth, arch perimeter, and molar angulation were assessed in all subjects at all observation times. T1-T2, T2-T3, and T1-T3 changes were compared statistically in the TG with respect to the corresponding CG.
  
  
  RESULTS
  Treatment with an acrylic splint RME followed by fixed appliances produced significantly favorable short-term and long-term changes in almost all maxillary and mandibular arch measurements. The amount of change in both maxillary and mandibular intermolar and intercanine widths fully corrected the initial discrepancies. Approximately 4 mm of long-term relative increase in maxillary arch perimeter, and 2.5 mm additional maintenance of mandibular arch perimeter were observed in the TG compared with the CG.
  
  
  CONCLUSIONS
  These results suggest that this protocol is effective and stable for the treatment of constricted maxillary arches, and can relieve modest deficiencies in arch perimeter.
authors: School of Dentistry, University of Michigan, Ann Arbor, MI 48109-1078, USA.
authors: Renée G
authors: RG
authors: Geran
authors: James A
authors: JA
authors: McNamara
authors: Tiziano
authors: T
authors: Baccetti
authors: Lorenzo
authors: L
authors: Franchi
authors: Lainie M
authors: LM
authors: Shapiro