title: Long-acting medications for the hyperkinetic disorders. A systematic review and European treatment guideline.
abstract: A systematic review of published and unpublished data on the use of long-acting medications in ADHD and hyperkinetic disorder is reported, giving effect sizes and numbers-to-treat for extended-release stimulant preparations and atomoxetine (ATX). A panel of experts from several European countries used the review to make recommendations about the use of these drugs in practice, and conclusions are reported: (1) Long-acting preparations should be available and used; (2) They should not replace short-acting drugs (which will be the initial treatment for many children for reasons of cost and flexibility of dosing). Individual clinical choice is needed. (3) Both ATX and extended-release preparations of stimulants should be available. The choice will depend upon the circumstances, and detailed recommendations are made.
authors: Dept. of Child & Adolescent Psychiatry/Psychotherapy, University of Goettingen, Von-Siebold-Str. 5, 37075 Goettingen, Germany. tbanasc@gwdg.de
authors: Tobias
authors: T
authors: Banaschewski
authors: David
authors: D
authors: Coghill
authors: Paramala
authors: P
authors: Santosh
authors: Alessandro
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authors: Zuddas
authors: Philip
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authors: Asherson
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authors: Buitelaar
authors: Marina
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authors: Danckaerts
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authors: Döpfner
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authors: SV
authors: Faraone
authors: Aribert
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authors: Rothenberger
authors: Joseph
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authors: Sergeant
authors: Hans-Christoph
authors: HC
authors: Steinhausen
authors: Edmund J S
authors: EJ
authors: Sonuga-Barke
authors: Eric
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authors: Taylor