spiro-Mamakone A: a unique relative of the spirobisnaphthalene class of compounds.
[structure: see text] A spirobisnaphthalene derivative with a new spiro-nonadiene skeleton, spiro-mamakone A (1), has been isolated from the extract of a cultured nonsporulating fungal endophyte derived from the New Zealand native tree Knightia excelsa (rewarewa). The carbon skeleton of spiro-mamakone A represents a new structural entity and an intriguing addition to the structurally diverse spirobisnaphthalene group of compounds. spiro-Mamakone A is potently cytotoxic and is also antimicrobial.
van der Sar
Sonia A
SA
Department of Chemistry, University of Canterbury, Christchurch, New Zealand.
Blunt
John W
JW
Munro
Murray H G
MH