[Structural and functional reorganization of the nonapeptidergic hypothalamic neurosecretory nuclei in experimental acute pancreatitis].
The structures of pancreas and hypothalamic magnocellular nuclei (supraoptic and paraventricular) were studied using light and electron microscopes in acute pancreatitis induced experimentally in mature male rats. Histo- and organotypic transformations of the pancreatic parenchymal and stromal elements were analyzed with a simultaneous cytological assessment of the hypothalamic nonapeptidergic neurosecretory centers. A phenomenon of the inhibition of hypothalamic nonapeptide release at the level in axo-vasal complexes was established, that aggravated the outcome of the destructive and necrobiotic processes in pathologically changed organ.
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