title: Evidence for growth-promoting effects of omega n - 3 fatty acids alone and in combination with a specific vitamin and mineral complex in rat neuroblastoma cells.
abstract: The beneficial effects of Omega n - 3 polyunsaturated fatty acids (n - 3 PUFA) in situations of cognitive impairment may be associated with enhanced neuronal growth. Since neuronal growth is impaired in n - 3 PUFA deficiency, and enhanced by certain vitamins and trace elements, the effects of n - 3 PUFA, vitamin and mineral cell complex (VMC) and their association on neuronal growth were investigated in cultured rat neuroblastoma cells. Treatment of cells for 3 days with n - 3 PUFA significantly enhanced neurite length without affecting the number of neurites or cells. VMC significantly increased cell number without affecting neurite length or their number. Combined n - 3 PUFA and VMC significantly enhanced all three growth parameters. The data confirm the growth promoting effects of n - 3 PUFA and VMC in cultured neurons over a relatively short time frame.
authors: Naturveda/Vitrobio Research Institute, ZAC de Lavaur, 63500 Issoire, France. naturveda@wanadoo.fr
authors: Ravi
authors: R
authors: Shrivastava
authors: Bernard
authors: B
authors: Vincent
authors: Stephane
authors: S
authors: Gobron
authors: Nathalie
authors: N
authors: Cucuat
authors: Gareth W
authors: GW
authors: John