title: Solution-phase parallel synthesis of a pyridinium pyrazol-3-olate inner salt library using a three-component reaction.
abstract: We present here the discovery of a novel, versatile, multicomponent reaction leading to various 4-[4-(pyridinium-1-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-2H-pyrazol-3-olate inner salts. The structure of the unusual zwitterionic inner salts was elucidated, and the scope of the novel reaction was investigated. After rapid optimization, the reaction was adapted to parallel synthesis, and an 800-membered compound library was produced.
authors: ComGenex Inc., Budapest, Hungary. laszlo.varga@comgenex.hu
authors: Laszló
authors: L
authors: Varga
authors: Tamas
authors: T
authors: Nagy
authors: György
authors: G
authors: Dorman
authors: Ferenc
authors: F
authors: Kalman
authors: Laszló
authors: L
authors: Urge
authors: Ferenc
authors: F
authors: Darvas