title: Conjunctive representation of position, direction, and velocity in entorhinal cortex.
abstract: Grid cells in the medial entorhinal cortex (MEC) are part of an environment-independent spatial coordinate system. To determine how information about location, direction, and distance is integrated in the grid-cell network, we recorded from each principal cell layer of MEC in rats that explored two-dimensional environments. Whereas layer II was predominated by grid cells, grid cells colocalized with head-direction cells and conjunctive grid x head-direction cells in the deeper layers. All cell types were modulated by running speed. The conjunction of positional, directional, and translational information in a single MEC cell type may enable grid coordinates to be updated during self-motion-based navigation.
authors: Centre for the Biology of Memory, Norwegian University of Science and Technology, 7489 Trondheim, Norway.
authors: Francesca
authors: F
authors: Sargolini
authors: Marianne
authors: M
authors: Fyhn
authors: Torkel
authors: T
authors: Hafting
authors: Bruce L
authors: BL
authors: McNaughton
authors: Menno P
authors: MP
authors: Witter
authors: May-Britt
authors: MB
authors: Moser
authors: Edvard I
authors: EI
authors: Moser