title: Model-based parameter recovery from uncalibrated optical images.
abstract: We propose a novel method for quantitative interpretation of uncalibrated optical images which is derived explicitly from an analysis of the image formation model. Parameters characterising the tissue are recovered from images acquired using filters optimised to minimise the error. Preliminary results are shown for the skin, where the technique was successfully applied to aid the diagnosis and interpretation of non-melanocytic skin cancers and acne; and for the more challenging ocular fundus, for mapping of the pigment xanthophyll.
authors: Astron Clinica, The Mount, Toft, Cambridge CB3 7RL, UK.
authors: S J
authors: SJ
authors: Preece
authors: I B
authors: IB
authors: Styles
authors: S D
authors: SD
authors: Cotton
authors: E
authors: E
authors: Claridge
authors: A
authors: A
authors: Calcagni