title: Randomized clinical study of Hydrofiber dressing with silver or silver sulfadiazine in the management of partial-thickness burns.
abstract: This prospective, randomized study compared protocols of care using either AQUACEL Ag Hydrofiber (ConvaTec, a Bristol-Myers Squibb company, Skillman, NJ) dressing with silver (n = 42) or silver sulfadiazine (n = 42) for up to 21 days in the management of partial-thickness burns covering 5% to 40% body surface area (BSA). AQUACEL Ag dressing was associated with less pain and anxiety during dressing changes, less burning and stinging during wear, fewer dressing changes, less nursing time, and fewer procedural medications. Silver sulfadiazine was associated with greater flexibility and ease of movement. Adverse events, including infection, were comparable between treatment groups. The AQUACEL Ag dressing protocol tended to have lower total treatment costs (Dollars 1040 vs. Dollars 1180) and a greater rate of re-epithelialization (73.8% vs 60.0%), resulting in cost-effectiveness per burn healed of Dollars 1,409.06 for AQUACEL Ag dressing and Dollars 1,967.95 for silver sulfadiazine. A protocol of care with AQUACEL(R) Ag provided clinical and economic benefits compared with silver sulfadiazine in patients with partial-thickness burns.
authors: Arizona Burn Center, Phoenix, Arizona 85008, USA.
authors: Daniel M
authors: DM
authors: Caruso
authors: Kevin N
authors: KN
authors: Foster
authors: Sigri A
authors: SA
authors: Blome-Eberwein
authors: John A
authors: JA
authors: Twomey
authors: David N
authors: DN
authors: Herndon
authors: Arnold
authors: A
authors: Luterman
authors: Paul
authors: P
authors: Silverstein
authors: Jeffrey R
authors: JR
authors: Antimarino
authors: Gregory J
authors: GJ
authors: Bauer