[Latent autoimmune diabetes in adults].
Latent autoimmune diabetes in adults (LADA) is a disorder with onset after age 30, insulin independence for at least 6 months after diagnosis, and the presence of circulating pancreatic islet autoantibodies. The prevalence of LADA varies substantially across ethnic groups and ranges approximately from 1% to 10% among patients with type 2 diabetes. In this review we discuss the nomenclature, diagnostic criteria, immunologic and genetic markers, metabolic alterations and therapy of this form of diabetes.
Maioli
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Istituto di Clinica Medica e Terapia Medica, Università degli Studi di Sassari, 07100 Sassari, Italia. marimaio@uniss.it
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