Nickel-catalyzed multicomponent connection of dimethylzinc, alkynes, 1,3-butadiene, aldehydes, and amines.
A nickel(0) species catalyzes the five-component connection reaction of dimethylzinc, alkynes, 1,3-butadiene, aldehydes, and amines, furnishing either 1 or 2 selectively in good yields depending on the kinds of amines, aromatic or aliphatic amines, respectively.
Kimura
Masanari
M
Department of Applied Chemistry, Faculty of Engineering, and Graduate School of Science and Technology, Nagasaki University, 1-14 Bunkyo, Nagasaki 852-8521, Japan.
Kojima
Keisuke
K
Tatsuyama
Yasushi
Y
Tamaru
Yoshinao
Y