[The research of the pathogen responsible for Pleurocybella porrigens related encephalopathy: investigation of 3-nitropropionic acid hypothesis].
Pleurocybella porrigens related encephalopathy exhibits consciousness disturbance and convulsion in the patients after taking and patients show bilateral basal ganglia lesion resulted in high mortality rate. This encephalopathy is a very similar to the moldy sugarcane encephalopathy epidemic in China in the past. We investigated the relationship between Pleurocybella porrigens related encephalopathy and 3-nitropropionic acid which had caused the moldy sugarcane encephalopathy. We have tried to detect 3-NPA in the various specimens from patients and Pleurocybella porrigens, but failed. Further examinations for elucidating the causation of Pleurocybella porrigens related encephalopathy are needed.
Obara
Koji
K
Department of Neurology, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Muto
Hajime
H
Itoh
Hideaki
H
Satoh
Shigeru
S
Gonmori
Kunio
K
Watanabe
Sumio
S
Toyoshima
Itaru
I