title: The implications of a growing evidence base for drug use in elderly patients. Part 3. Beta-adrenoceptor blockers in heart failure and thrombolytics in acute myocardial infarction.
abstract: Beta-adrenoceptor blockers and thrombolytic agents are of established value in the pharmacological management of heart failure and ST-elevation myocardial infarction, respectively. However, there is uncertainty as to whether these therapeutic strategies can be safely and effectively adopted in elderly patients with comorbidities, particularly in old-old individuals. This review focuses on these trials and the age-related efficacy and safety of these drugs.
authors: Department of Clinical Pharmacology and Centre for Neuroscience, Flinders University, Adelaide, Australia. arduino.mangoni@flinders.edu.au
authors: A A
authors: AA
authors: Mangoni
authors: S H D
authors: SH
authors: Jackson