title: Automatic detection of patients with nosocomial infection by a computer-based surveillance system: a validation study in a general hospital.
abstract: OBJECTIVE
  To validate an automated system for the detection of patients with nosocomial infection (NI) in an intensive care unit (ICU).
  
  
  METHODS
  Retrospective analysis of data from the hospital information system. We applied 3 different NI suspicion criteria (positive microbiology reports, antibiotic administration, and diagnosis of clinical infection) and compared the results to those of a prospective NI incidence study done in the ICU during the same period (1999-2002).
  
  
  METHODS
  A 250-bed general hospital in Barcelona, Spain.
  
  
  METHODS
  From April 15, 1999, through June 30, 2002, 1380 patients were admitted to the ICU. Of these, 1043 had an ICU stay of more than 24 hours and were included in the study.
  
  
  RESULTS
  At least one NI suspicion criterion was present for 242 patients (23.2%); 2 criteria were present for 184 patients (17.6%); and all 3 criteria were present for 112 (11.7%). Comparison of hospital information system data to the results of the prospective study indicated that the combination of 2 criteria demonstrated the most satisfactory sensitivity (94.3%; 95% confidence interval [CI], 79.5%-99.0%) and specificity (83.6%; 95% CI, 76.8%-88.9%). The positive predictive value was 55.9% (95% CI, 42.5%-68.6%); the negative predictive value was 98.5% (95% CI, 94.2%-99.7%). The system could assign a site of infection for 90.4% of the NIs detected.
  
  
  CONCLUSIONS
  The hospital information system was a useful tool for retrospectively detecting patients with an NI during the ICU stay. Given its high sensitivity, it may be useful as an alert for the NI team.
authors: Preventive Medicine Department, School of Medicine, Autonomous University of Barcelona, Barcelona, Spain.
authors: L
authors: L
authors: Pokorny
authors: A
authors: A
authors: Rovira
authors: M
authors: M
authors: Martín-Baranera
authors: C
authors: C
authors: Gimeno
authors: C
authors: C
authors: Alonso-Tarrés
authors: J
authors: J
authors: Vilarasau