title: Simple protocol for NMR analysis of the enantiomeric purity of diols.
abstract: [reaction: see text] A practically simple three-component chiral derivatization protocol for determining the enantiopurity of chiral 1,2-, 1,3-, and 1,4-diols by (1)H NMR spectroscopic analysis is described. The method involves treatment with 2-formylphenylboronic acid and enantiopure alpha-methylbenzylamine to afford a mixture of diastereoisomeric iminoboronate esters whose ratio is an accurate reflection of the enantiopurity of the parent diol.
authors: Department of Chemistry, University of Bath, UK.
authors: Andrew M
authors: AM
authors: Kelly
authors: Yolanda
authors: Y
authors: Pérez-Fuertes
authors: Susumu
authors: S
authors: Arimori
authors: Steven D
authors: SD
authors: Bull
authors: Tony D
authors: TD
authors: James