title: Palladium-catalyzed Suzuki cross-coupling of 2-haloselenophenes: synthesis of 2-arylselenophenes, 2,5-diarylselenophenes, and 2-arylselenophenyl ketones.
abstract: We present herein our results on the Suzuki coupling reaction of 2-haloselenophenes with boronic acids catalyzed by palladium salt and describe a new route established to prepare 2-arylselenophenes and 2,5-diarylselenophenes in good yields. The reaction proceeded cleanly under mild conditions and was performed with aryl boronic acids bearing electron-withdrawing, electron-donating, and neutral substituents, in the presence of Pd(OAc)2, K2CO3/H2O in DME. In addition, by this protocol unsymmetrical aryl ketones were also obtained from 2-iodoselenophene and boronic acids via a carbonylative process.
authors: Laboratório de Síntese, Reatividade, Avaliação Farmacológica e Toxicológica de Organocalcogênios, CCNE, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil 97105-900.
authors: Patrícia
authors: P
authors: Prediger
authors: Angélica V
authors: AV
authors: Moro
authors: Cristina W
authors: CW
authors: Nogueira
authors: Lucielli
authors: L
authors: Savegnago
authors: Paulo Henrique
authors: PH
authors: Menezes
authors: João B T
authors: JB
authors: Rocha
authors: Gilson
authors: G
authors: Zeni