Refractory hematuria from amyloidosis successfully treated by splenectomy.
Systemic amyloidosis can result in a coagulopathy that is associated with low levels of factor X. We present a case of intractable, life-threatening hematuria that was successfully managed with activated recombinant human factor VII and splenectomy.
Ma
Jian F
JF
Department of Urology, Stanford University School of Medicine, Stanford, California 94305, USA.
Coutre
Steven E
SE
Curet
Myriam J
MJ
Brooks
James D
JD
D000686:Amyloidosis / Q000150:complications*; D016913:Blood Component Transfusion; D003029:Coagulants / Q000627:therapeutic use; D003558:Cystoscopy; D015942:Factor VIIa / Q000627:therapeutic use; D005171:Factor X Deficiency / Q000209:etiology* / Q000628:therapy; D006417:Hematuria / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D013156:Splenectomy; D016896:Treatment Outcome
D003029:Coagulants; D015942:Factor VIIa