title: [Computer simulation methods of cardiac electrophysiology].
abstract: Computer simulation is one of the powerful protocols to study electrophysiology theoretically. In this paper,the algorithm of Rush and Larsen was used to solve the ordinary differential equations (ODE's) in the Luo-Rudy models of mammalian ventricular cell. The operator splitting and adaptive time step methods were used to solve the partial differential equations (PDE's) in cardiac tissue conduction models. Using these methods we accomplished the simulation programs of single ventricular cell model and two-dimensional (2-D) tissue model. The methods of initiating spiral waves were studied with this software. The data obtained from 2-D simulation can be used for further study on isopotential contour lines, spiral wave tip trajectories, and pseudo-ECG.
authors.affiliation: College of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
authors.forename: Yinbin
authors.initials: Y
authors.lastname: Jin
authors.forename: Lin
authors.initials: L
authors.lastname: Yang
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Yezhuo
authors.initials: Y
authors.lastname: Huang
authors.forename: Dazong
authors.initials: D
authors.lastname: Jiang
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004562:Electrocardiography; D004594:Electrophysiology; D006352:Heart Ventricles / Q000166:cytology; D006801:Humans; D008955:Models, Cardiovascular; D032383:Myocytes, Cardiac / Q000502:physiology*; D012984:Software; D016276:Ventricular Function