[Lung protection with anesthetics].
Common inhaled and intravenous anesthetics except the barbiturate are recommended for the patients with bronco-constrictive lung disease because of their bronco-dilating property. However there are pharmacological potency differences between individual anesthetics. The halogenated inhaled anesthetics and propofol exert antiinflammatory effect on acute lung injury and acute respiratory distress syndrome in the laboratory level, but further study is required for future clinical application. These anesthetics also have an organ protective effect on the ischemia reperfusion lung injury, and their clinical application is expected in the lung transplantation surgery.
Ishibe
Yuichi
Y
Tottori University Hospital, Department of Surgery, Division of Anesthesiology and Critical Care Medicine, Yonago 683-8504.
Mochida
Shinsuke
S
Funaki
Kazumi
K
D000777:Anesthetics / Q000494:pharmacology*; D018685:Anesthetics, Inhalation / Q000494:pharmacology; D018686:Anesthetics, Intravenous / Q000494:pharmacology; D000818:Animals; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000473:pathology; D008171:Lung Diseases / Q000150:complications; D020011:Protective Agents / Q000494:pharmacology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology; D015427:Reperfusion Injury / Q000209:etiology / Q000517:prevention & control; D012121:Respiration, Artificial / Q000009:adverse effects; D012128:Respiratory Distress Syndrome / Q000209:etiology
D000777:Anesthetics; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D020011:Protective Agents