title: Conformational change of membrane proteins leads to shape changes of red blood cells.
abstract: High-resolution atomic force microscopy (AFM) allows a new insight into the surface of mammalian cells. Using the human red blood cell (RBC) as a model, we have demonstrated an important correlation between the conformation of membrane proteins measured from the external face of the cell and the cell shape.
authors.affiliation: Laboratory of Biophysics, Saarland University, P.O. Box 151150, 66041 Saarbrücken, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Betz
authors.forename: Udo
authors.initials: U
authors.lastname: Bakowsky
authors.forename: Michael R
authors.initials: MR
authors.lastname: Müller
authors.forename: Claus-Michael
authors.initials: CM
authors.lastname: Lehr
authors.forename: Ingolf
authors.initials: I
authors.lastname: Bernhardt
mesh_terms: D048430:Cell Shape; D004912:Erythrocytes / Q000166:cytology* / Q000648:ultrastructure*; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry* / Q000648:ultrastructure*; D018625:Microscopy, Atomic Force
chemical_list: D008565:Membrane Proteins