[Survey of study on the extraction, purification and determination methods of glycyrrhizic acid in Licorice].
Extraction, purification and determination methods of glycyrrhizic acid in Licorice are surveyed in this paper. The extracting efficiency of dilute ethanol solvent for glycyrrhizic acid is higher than water extraction, and ammonia appended to ethanol solution can increase the effect of extraction. Ultrasound method, microwave-assisted method and supercritical CO2 fluid extraction are more effective than the conventional techniques, due to the short extraction time, low consumption of solution and energy. The modem analytical methods such as TLCs, HPLC and CE can determine the content of glycyrrhizic acid rapidly and exactly.
Lu
Shou-ping
SP
College of Agronomy and Biotechnology, China Agricultural University, Beijing.
Sun
Qun
Q
Wang
Jian-hua
JH
Sun
Bao-qi
BQ
D000641:Ammonia; D002851:Chromatography, High Pressure Liquid; D025924:Chromatography, Supercritical Fluid; D002855:Chromatography, Thin Layer; D019075:Electrophoresis, Capillary; D000431:Ethanol; D006035:Glycyrrhiza / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000032:analysis / Q000302:isolation & purification*; D008872:Microwaves; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014465:Ultrasonics
D000431:Ethanol; D019695:Glycyrrhizic Acid; D000641:Ammonia