title: DNA architecture: from G to Z.
abstract: G-quadruplexes and Z-DNA are two important non-B forms of DNA architecture. Results on novel structural elements, folding and unfolding kinetics, and interactions with small molecules and proteins have been reported recently for these forms. These results will enhance our understanding of the biology of these structures and provide a platform for drug design.
authors.affiliation: Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. phantuan@mskcc.org
authors.forename: Anh Tuân
authors.initials: AT
authors.lastname: Phan
authors.forename: Vitaly
authors.initials: V
authors.lastname: Kuryavyi
authors.forename: Dinshaw J
authors.initials: DJ
authors.lastname: Patel
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D043542:DNA, Z-Form / Q000737:chemistry; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009692:Nucleic Acid Heteroduplexes
chemical_list: D043542:DNA, Z-Form; D009692:Nucleic Acid Heteroduplexes; D004247:DNA