The role of an organ exchange organization in increasing split-liver transplantation.
Eurotransplant introduced a new allocation policy in January 2003 to increase the number of liver transplants by offering centers an incentive to split deceased donor livers for 2 recipients. Centers were granted the option of choosing a suitable recipient for the second portion of the split liver from their own waiting list and, to increase the awareness for liver splitting, centers were asked by the Eurotransplant duty officer whether they would consider splitting whenever a liver that met the 50/50 rule (donor age <50 and weight >50 kg) was available. During the first year after implementing this policy, split-liver transplants increased by 67% and again by 10% during the second year (a total of 288 transplants in the 2-year period). The number of pediatric recipients of a split liver increased from 44 in 2002 to 76 in 2004 and the pediatric waiting list decreased by 36% (73 to 47) one year after implementation of the new policy. More than 95% of the 288 split liver transplants involved one adult and one pediatric recipient. Nearly three-quarters of the split liver transplants were performed at 3 centers with both a pediatric and adult waiting list and with surgeons experienced in the procedure. We conclude that Eurotransplant's liver allocation policy has increased the number of liver transplants, particularly among children, by rewarding centers that split livers for transplantation to 2 recipients without prolonging cold ischemia time. The number of centers that could benefit from this policy will increase as more surgeons are trained in the splitting procedure.
Gerling
Till
T
Eurotransplant International Foundation, Leiden, The Netherlands.
Karbe
Thomas
T
Kütemeier
Robert
R
de Vries
Erwin
E
Lerut
Jan P M
JP
Persijn
Guido G
GG
Hauss
Jan
J
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005060:Europe; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016031:Liver Transplantation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D013997:Time Factors; D020858:Tissue and Organ Harvesting; D009927:Tissue and Organ Procurement / Q000331:legislation & jurisprudence / Q000458:organization & administration* / Q000706:statistics & numerical data; D014850:Waiting Lists