title: [Peculiarities of theophylline and prolactin interaction and calcium fluctuation from intracellular stores of porcine oocytes in the presence of estradiol].
abstract: Using a fluorescent dye chlortetracycline, a study was made of the effect of estradiol on the interaction of theophylline and prolactin in the course of Ca2+ exit from intracellular stores of pig oocytes, isolated from ovaries at the stage of follicle growth. It is shown that in the presence of estradiol, prolactin does not stimulate Ca2+ exit from intracellular stores of pig oocytes. The action of theophylline similarly does not stimulate Ca2+ exit. Unlike, a joint effect of theophylline and prolactin on pig oocytes in the presence estradiol stimulated Ca2+ exit from intracellular stores of pig oocytes. These data demonstrated the influence of estradiol on theophylline and prolactin stimulated Ca2+ exit from intracellular stores of pig oocytes.
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Denisenko
authors.forename: T I
authors.initials: TI
authors.lastname: Kuz'mina
mesh_terms: D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D002751:Chlortetracycline; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D066298:In Vitro Techniques; D009865:Oocytes / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D011388:Prolactin / Q000378:metabolism*; D013552:Swine; D013806:Theophylline / Q000378:metabolism*
chemical_list: D004958:Estradiol; D011388:Prolactin; D013806:Theophylline; D002118:Calcium; D002751:Chlortetracycline