title: Living-related liver transplantation with removal of inferior vena cava for unresectable hepatoblastoma.
abstract: We report a case of a two-yr-old boy with hepatoblastoma resectable only by total hepatectomy including the vena cava. Successful LTx was performed with a living donor segment without vena cava reconstruction. The tumor was located in the bilateral lobe, surrounding the IVC. In spite of the high-dose chemotherapy, the tumor did not become resectable. LTx was performed using left lateral segment after removal of the IVC combined with total hepatectomy. Because the collaterals were well developed, the patient tolerated the procedure well. The serum AFP level decreased from 186 699 to 8 ng/mL in 11 months after LTx without local recurrence or distant metastasis.
authors.affiliation: Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan. toshi@pedsurg.med.osaka-u.ac.jp
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Takuya
authors.initials: T
authors.lastname: Kimura
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ihara
authors.forename: Yuko
authors.initials: Y
authors.lastname: Tazuke
authors.forename: Akihiro
authors.initials: A
authors.lastname: Yoneda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kusafuka
authors.forename: Masahiro
authors.initials: M
authors.lastname: Fukuzawa
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Okuyama
authors.forename: Masami
authors.initials: M
authors.lastname: Inoue
mesh_terms: D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005220:Fathers; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D018197:Hepatoblastoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D011859:Radiography; D013997:Time Factors; D016896:Treatment Outcome; D014682:Vena Cava, Inferior / Q000601:surgery*
chemical_list: D007166:Immunosuppressive Agents; D003520:Cyclophosphamide