title: Factors associated with psychiatric hospitalization of individuals diagnosed with dementia and comorbid bipolar disorder.
abstract: The objective was to determine risk factors of psychiatric hospitalization among a Veterans Administration database of patients with dementia and comorbid bipolar disorder (D+BD). Patients with D+BD had a greater prevalence of psychiatric hospitalization (28% vs 4%). The strongest predictor of psychiatric hospitalization was the presence of an alcohol use disorder (51% risk); patients without alcohol use disorders but under the age of 70 had the next highest risk (33% risk). However, patients with an alcohol use disorder had shorter psychiatric hospitalizations than those without. Compared with patients without BD, D+BD patients were more likely to have alcohol use disorders (15% vs 3%) and any other substance use problem (10% vs 1%). In patients diagnosed with dementia and bipolar disorder, the strongest risk factor for psychiatric hospitalization was an alcohol abuse disorder. These findings suggest that disorders with increased frequency in BD affect the course of dementia.
authors.affiliation: Palo Alto Veterans Affairs Health Care System, Palo Alto, California 94304, USA. john-brooks@stanford.edu
authors.forename: John O
authors.initials: JO
authors.lastname: Brooks
authors.forename: Jennifer C
authors.initials: JC
authors.lastname: Hoblyn
authors.forename: Helena Chmura
authors.initials: HC
authors.lastname: Kraemer
authors.forename: Jerome A
authors.initials: JA
authors.lastname: Yesavage
mesh_terms: D000367:Age Factors; D000368:Aged; D000544:Alzheimer Disease / Q000453:epidemiology; D001714:Bipolar Disorder / Q000453:epidemiology*; D015897:Comorbidity; D019992:Databases as Topic; D003704:Dementia / Q000453:epidemiology*; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006787:Hospitals, Veterans; D006801:Humans; D007902:Length of Stay; D008297:Male; D008605:Mental Health Services; D010359:Patient Readmission; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000453:epidemiology; D014481:United States