FCP: functional coverage of the proteome by structures.
BACKGROUND
Tools and resources for translating the remarkable growth witnessed in recent years in the number of protein structures determined experimentally into actual gain in the functional coverage of the proteome are becoming increasingly necessary. We introduce FCP, a publicly accessible web tool dedicated to analyzing the current state and trends of the population of structures within protein families. FCP offers both graphical and quantitative data on the degree of functional coverage of enzymes and nuclear receptors by existing structures, as well as on the bias observed in the distribution of structures along their respective functional classification schemes.


BACKGROUND
http://cgl.imim.es/fcp


BACKGROUND
jmestres@imim.es.
García-Serna
Ricard
R
Chemogenomics Laboratory, Research Unit on Biomedical Informatics, Institut Municipal d'Investigació Mèdica and Universitat Pompeu Fabra, Dr Aiguader 88, 08003 Barcelona, Catalonia, Spain.
Opatowski
Lulla
L
Mestres
Jordi
J
D000465:Algorithms; D000595:Amino Acid Sequence; D003628:Database Management Systems; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D008969:Molecular Sequence Data; D020543:Proteome / Q000737:chemistry* / Q000145:classification* / Q000378:metabolism; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
D020543:Proteome