Dynamic clamp analyses of cardiac, endocrine, and neural function.
The dynamic clamp introduces artificial conductances into cells to simulate electrical coupling, votage-dependent, leak, and synaptic conductances. This review describes how the dynamic clamp has been used to address various questions in the cardiac, endocrine, and nervous systems.
Goaillard
Jean-Marc
JM
Volen Center and Biology Department, Brandeis University, Waltham, Massachusetts, USA.
Marder
Eve
E
D000818:Animals; D002450:Cell Communication; D023902:Chromosome Pairing / Q000502:physiology; D004553:Electric Conductivity; D004703:Endocrine System / Q000502:physiology*; D006321:Heart / Q000502:physiology*; D006329:Heart Conduction System / Q000502:physiology; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology; D009424:Nervous System Physiological Phenomena; D009431:Neural Conduction / Q000502:physiology; D018408:Patch-Clamp Techniques / Q000379:methods*