Frequency and clinical determinants of poststroke cognitive impairment in nondemented stroke patients.
The objective of this study was to examine the prevalence and clinical correlates of poststroke cognitive impairment in Chinese stroke patients in Hong Kong. One hundred seventy-nine stroke patients were interviewed by a psychiatrist 3 months after their stroke. Cognitive impairment was determined according to the Mini-Mental State Examination score. Thirty-nine participants (21.8%) had cognitive impairment. Univariate analysis found that cognitive impairment was associated with age, female sex, level of education, previous stroke, prestroke Rankin score, National Institutes of Health Stroke Scale dysarthria and total scores, urinary incontinence, and cerebral atrophy index. Multivariate logistic regression suggested that female sex, education, National Institutes of Health Stroke Scale dysarthria score, urinary incontinence, and atrial fibrillation were independent risk factors of poststroke cognitive impairment. After removal of 54 patients with previous stroke from the sample, the frequency of cognitive impairment decreased to 18.4%. It was concluded that cognitive impairment is common among nondemented Chinese stroke patients in Hong Kong.
Tang
Wai Kwong
WK
Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China. tangwk@cuhk.edu.hk
Chan
Sandra S M
SS
Chiu
Helen F K
HF
Ungvari
Gabor S
GS
Wong
Ka Sing
KS
Kwok
Timothy C Y
TC
Mok
Vincent
V
Wong
K T
KT
Richards
Polly S
PS
Ahuja
Anil T
AT
D000367:Age Factors; D000368:Aged; D003072:Cognition Disorders / Q000453:epidemiology* / Q000208:ethnology; D004522:Educational Status; D005260:Female; D006723:Hong Kong / Q000453:epidemiology / Q000208:ethnology; D006801:Humans; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000150:complications* / Q000175:diagnosis; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014549:Urinary Incontinence