title: Desymmetrization of diols by a tandem oxidation/Wittig olefination reaction.
abstract: Diols are desymmetrized by a tandem oxidation/Wittig olefination to give alpha,beta-unsaturated hydroxy esters without the requirement for protecting group strategies; the alpha,beta-unsaturated hydroxy esters are transformed into dienyl diesters using a second oxidation/Wittig olefination sequence using PCC.
authors.affiliation: Department of Chemistry, University of Wales Swansea, Singleton Park, Swansea, UK SA2 8PP.
authors.forename: David J
authors.initials: DJ
authors.lastname: Phillips
authors.forename: Kathryn S
authors.initials: KS
authors.lastname: Pillinger
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Angela E
authors.initials: AE
authors.lastname: Taylor
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Graham
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002072:Butylene Glycols / Q000737:chemistry*; D002625:Chemistry, Organic; D004952:Esters / Q000737:chemistry*; D017895:Manganese Compounds / Q000737:chemistry; D055601:Organic Chemistry Phenomena; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D002072:Butylene Glycols; D004952:Esters; D017895:Manganese Compounds; D010087:Oxides; C039681:1,4-butanediol; C016552:manganese dioxide