title: Glaucoma and increased central corneal thickness in aphakic and pseudophakic patients after congenital cataract surgery.
abstract: OBJECTIVE
  To compare the mean central corneal thickness (CCT) among aphakic and pseudophakic patients following congenital cataract surgery with age matched controls.
  
  
  METHODS
  This study included 43 eyes of 43 aphakic and pseudophakic patients following congenital cataract surgery. 44 healthy, age and sex matched volunteers were recruited for comparison with the patients. After a complete eye examination, corneal thickness and intraocular pressure were measured.
  
  
  RESULTS
  In the study group, 33 eyes were aphakic, and the remaining 10 eyes were pseudophakic. The median CCT was 556.0 microm (range 490-640 microm) in the control group and 626 microm (range 523-870 microm) in the study group (p<0.05). There was a significant difference in CCT between aphakic and pseudophakic eyes in which an intraocular lens (IOL) had been implanted at the time of congenital cataract surgery (p = 0.011). The same difference was not observed between aphakic and pseudophakic eyes in which an IOL had been implanted secondarily (p = 0.835). The median age of the patients at the time of lensectomy was 24 months (range 1 week to 120 months). There was a negative correlation between the age at lensectomy and CCT (r = -0.485, p = 0.001).
  
  
  CONCLUSIONS
  Aphakic and pseudophakic patients have significantly thicker corneas than age matched controls. This difference can have an important effect on interpreting intraocular pressures in these patients. It is also important to assess the effects of early surgery for congenital cataracts, as well as those of primary and secondary IOL implantation, on CCT.
authors.affiliation: Department of Glaucoma, Ulucanlar Teaching and Research Eye Hospital, Ankara, Turkey. tulaysimsek@hotmail.com
authors.forename: T
authors.initials: T
authors.lastname: Simsek
authors.forename: A H
authors.initials: AH
authors.lastname: Mutluay
authors.forename: U
authors.initials: U
authors.lastname: Elgin
authors.forename: R
authors.initials: R
authors.lastname: Gursel
authors.forename: A
authors.initials: A
authors.lastname: Batman
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001036:Aphakia, Postcataract / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology*; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D011446:Prospective Studies; D019591:Pseudophakia / Q000150:complications / Q000473:pathology* / Q000503:physiopathology