Chiral seleno-amines from indium selenolates. A straightforward synthesis of selenocysteine derivatives.
A simple and efficient procedure for the synthesis of chiral beta-seleno-amines derivatives from a one-pot indium(I) iodide-mediated aziridine ring opening with diorganoyl diselenides has been developed. As an application, the synthesis of selenocysteine and selenotreonine derivatives has been accomplished.
Braga
Antonio L
AL
Departamento de Química, Universidade Federal de Santa Maria, Santa Maria, RS, 97105-900, Brazil. albraga@quimica.ufsm.br
Schneider
Paulo H
PH
Paixão
Marcio W
MW
Deobald
Anna M
AM
Peppe
Clovis
C
Bottega
Diana P
DP
D000588:Amines / Q000138:chemical synthesis*; D007204:Indium / Q000737:chemistry*; D015394:Molecular Structure; D017279:Selenocysteine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
D000588:Amines; D007204:Indium; D017279:Selenocysteine