title: New stationary phases for high-performance liquid chromatography based on poly(methyltetradecylsiloxane) thermally immobilized onto zirconized silica.
abstract: The modification of silica with zirconium oxide followed by sorption and thermal immobilization of poly(methyltetradecylsiloxane) (PMTDS) is used to prepare a reversed stationary phase for high-performance liquid chromatography. The thermal immobilization of PMTDS on zirconized silica was optimized using a central composite design. The new stationary phase was characterized by spectroscopic and chromatographic methods. Stationary phases with good reproducibility and good chromatographic performance for various compounds were obtained. PMTDS thermally immobilized on zirconized silica presented quite significant chemical stability at pH 10 and 50 degrees C.
authors.affiliation: Instituto de Química, Universidade Estadual de Campinas, Caixa Postal 6154, 13084-971 Campinas, SP, Brazil.
authors.forename: Anizio M
authors.initials: AM
authors.lastname: Faria
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Collins
authors.forename: Carol H
authors.initials: CH
authors.lastname: Collins
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D015394:Molecular Structure; D011090:Polyenes; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D015203:Reproducibility of Results; D012822:Silicon Dioxide / Q000737:chemistry*; D012833:Siloxanes / Q000138:chemical synthesis / Q000737:chemistry*; D013696:Temperature; D013818:Thermogravimetry / Q000379:methods; D015040:Zirconium / Q000737:chemistry*
chemical_list: D011090:Polyenes; D011108:Polymers; D012833:Siloxanes; C513729:poly(methyltetradecylsiloxane); D012822:Silicon Dioxide; C021245:poly(methylpentene); D015040:Zirconium; C028541:zirconium oxide