Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico.
We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to T. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogs from Toluca, an area previously considered free of T. cruzi. Our data demonstrate the need for active epidemiologic surveillance programs in these regions. A direct correlation (r2 = 0.955) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. cruzi infection in these areas.
Estrada-Franco
Jose G
JG
University of Texas Medical Branch, Galveston, Texas 77555, USA.
Bhatia
Vandanajay
V
Diaz-Albiter
Hector
H
Ochoa-Garcia
Laucel
L
Barbabosa
Alberto
A
Vazquez-Chagoyan
Juan C
JC
Martinez-Perez
Miguel A
MA
Guzman-Bracho
Carmen
C
Garg
Nisha
N
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D014355:Chagas Disease / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology*; D004285:Dogs; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008800:Mexico / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D014349:Trypanosoma cruzi / Q000276:immunology / Q000302:isolation & purification*
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M