title: [Kawasaki disease: heart disease during childhood].
abstract: The aim of this study was to determine risk factors for coronary lesions, the type of heart lesion present, and long-term outcome in Kawasaki disease. We studied 150 children, aged 3 months to 9.5 years, who met the criteria for a diagnosis of Kawasaki disease. Of the 18% who were diagnosed with heart disease, 100% had coronary artery abnormalities, 11.1% had pancarditis, and 3.7%, mitral insufficiency. The coronary abnormalities were classified according severity as follows: diffuse ectasia in 40.7%; a small-to-medium-sized solitary coronary artery aneurysm in 33.3%; numerous small-to-medium-sized aneurysms in 11.1%; giant aneurysms in 11.1%; and coronary artery stenosis in 3.7%. The presence of pancarditis was a predictor of a giant coronary artery aneurysm. Mortality was 3.7%. Coronary aneurysm was the predominant heart lesion. The risk factors for coronary aneurysm in Kawasaki disease included age less than 27 months, fever lasting more than 8 days, erythrocyte sedimentation greater than 70 mm, and pancarditis.
authors.affiliation: Servicio de Cardiología Infantil, Hospital Pediátrico Dr. Humberto J. Notti, Mendoza, Argentina. schroh_md@hotmail.com
authors.forename: Ana M
authors.initials: AM
authors.lastname: Schroh
authors.forename: Pablo
authors.initials: P
authors.lastname: Domínguez
authors.forename: Lidia B
authors.initials: LB
authors.lastname: Laghezza
authors.forename: Pablo A
authors.initials: PA
authors.lastname: Melonari
authors.forename: Marisa
authors.initials: M
authors.lastname: Olguín
authors.forename: Roberto
authors.initials: R
authors.lastname: Miatello
mesh_terms: D002648:Child; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*