title: [Epidemiology of gastrointestinal bleeding in the elderly].
abstract: The epidemiological pattern of gastrointestinal bleed in western countries has been steadily changing over the last few years given the rising prevalence of an elderly population. In a one year prospective study at a referral hospital in Zurich, Switzerland, hospitalised patients were investigated with regards to the epidemiology of gastrointestinal (GI) bleeding. Of 7406 hospitalisations, a total number of 224 GI bleeds were registered (53% women, mean age 71 +/- 16, 63% with relevant co morbidities). Of 197 patients with GI bleeds, 51% had upper and 37% lower gastrointestinal bleedings. 2% had concurrent upper and lower gastrointestinal bleedings and 10% remained unexplained. The following spectrum of lesions identified as bleeding sources was: 24% ulcer bleedings, 16% diverticular bleedings, 10% colitis, 10% esophagitis and 6% Mallory-Weiss lesions. The frequency of bleeds significantly increased with patient's age. In addition, diverticular bleeding in the elderly was highly associated with intake of Aspirin. The prognosis of gastrointestinal bleeding in elderly patients in this study was excellent with a bleeding associated mortality of only 3.1%.
authors.affiliation: Gastroenterologie, Stadtspital Waid, Zürich. geyer@gastroenterologie-wettingen.ch
authors.forename: M
authors.initials: M
authors.lastname: Geyer
authors.forename: I
authors.initials: I
authors.lastname: Stamenic
authors.forename: H
authors.initials: H
authors.lastname: Bühler
authors.forename: P
authors.initials: P
authors.lastname: Bertschinger
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016888:Angiodysplasia / Q000150:complications / Q000453:epidemiology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D001241:Aspirin / Q000009:adverse effects; D003092:Colitis / Q000150:complications / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000150:complications / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004240:Diverticulum / Q000150:complications / Q000453:epidemiology; D004381:Duodenal Ulcer / Q000150:complications / Q000453:epidemiology; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000453:epidemiology; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D006484:Hemorrhoids / Q000150:complications / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D008297:Male; D008309:Mallory-Weiss Syndrome / Q000150:complications / Q000453:epidemiology; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000453:epidemiology / Q000209:etiology; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects; D011446:Prospective Studies; D012737:Sex Factors; D013557:Switzerland / Q000453:epidemiology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin