A toddler with recurrent oral and genital ulcers.
In western countries, when a child presents with recurrent oral ulcers and colitis, the diagnosis of Crohn's disease is mostly made. In our patient, the diagnosis was Behçet's disease with gastrointestinal manifestations. Behçet's disease with gastrointestinal manifestations has a similar clinical presentation to Crohn's disease, but there is more organ involvement and the prognosis is more severe in the former. Because there is limited experience in the treatment of Behçet's disease in the paediatric population, successful and unsuccessful treatment modalities in both paediatric and adult populations should be reported.
Yüksel
Zehre
Z
Paediatric Gastroenterology, Department of Paediatrics, Leiden University Medical Centre, Free University Medical Centre, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. z.yuksel@lumc.nl
Schweizer
Joachim J
JJ
Mourad-Baars
Petronella E C
PE
Sukhai
Ram N
RN
Mearin
Luisa M
LM
D018501:Antirheumatic Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003093:Colitis, Ulcerative / Q000209:etiology*; D003424:Crohn Disease / Q000175:diagnosis; D003937:Diagnosis, Differential; D005183:Failure to Thrive / Q000209:etiology*; D005260:Female; D005401:Fissure in Ano / Q000209:etiology*; D006801:Humans; D007223:Infant; D019226:Oral Ulcer / Q000209:etiology*; D010502:Perineum / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha