The phosphate-starvation response of Bacillus licheniformis.
The phosphate-starvation stimulon of Bacillus licheniformis was analyzed at the transcriptional and translational level. The comparison of the transcriptome and the proteome demonstrated that this specific starvation response of B. licheniformis is partially similar to that of B. subtilis. However, it is also shown that B. licheniformis has evolved its own strategies to cope with this nutrient limitation. By means of the secretome analysis the phytase was identified as the most abundant protein under phosphate-starvation conditions. Data of this study indicate that, unlike in B. subtilis, phosphate starvation in B. licheniformis does not induce the SigmaB-dependent general stress response.
Hoi
Le Thi
le T
Institut für Pharmazie, Ernst-Moritz-Arndt Universität, Greifswald, Germany.
Voigt
Birgit
B
Jürgen
Britta
B
Ehrenreich
Armin
A
Gottschalk
Gerhard
G
Evers
Stefan
S
Feesche
Jörg
J
Maurer
Karl-Heinz
KH
Hecker
Michael
M
Schweder
Thomas
T
D010832:6-Phytase / Q000378:metabolism; D001407:Bacillus / Q000737:chemistry* / Q000201:enzymology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D019295:Computational Biology; D003470:Culture Media / Q000737:chemistry; D015180:Electrophoresis, Gel, Two-Dimensional; D005798:Genes, Bacterial; D010446:Peptide Fragments / Q000737:chemistry; D010449:Peptide Mapping; D010710:Phosphates / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D020543:Proteome / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism; D013217:Starvation / Q000378:metabolism*; D014158:Transcription, Genetic
D001426:Bacterial Proteins; D003470:Culture Media; D010446:Peptide Fragments; D010710:Phosphates; D020543:Proteome; D012333:RNA, Messenger; D010832:6-Phytase