title: Subjective quality of life of patients with obsessive-compulsive disorder.
abstract: BACKGROUND
  Obsessive-compulsive disorder (OCD) is the fourth most frequent diagnosis in psychiatry. Patients with OCD suffer from obsessive thinking and compulsive behavior, which impact their everyday life negatively.
  
  
  OBJECTIVE
  Subjective quality of life (QoL) in patients with OCD was examined and compared to the general German population and to patients with schizophrenia.
  
  
  METHODS
  Seventy-five patients, aged 21-72, with OCD (ICD 10 F42.0-F42.2) were recruited from the outpatient clinic for anxiety disorders at the Department of Psychiatry of the University of Leipzig. By means of the WHOQOL-BREF, QoL was assessed in patients with OCD in a representative sample of patients with schizophrenia and in a sample of the general population of Saxony/Germany.
  
  
  RESULTS
  Compared with the general population, QoL in patients with OCDs was lower in all domains of the WHOQOL-BREF. Unexpectedly, QoL in patients with OCDs was lower in the domains "psychological well-being" and "social relationships" when compared with schizophrenia patients.
  
  
  CONCLUSIONS
  OCD has a substantial adverse effect on patients' subjective QoL, which may be even greater than the adverse effect of schizophrenia. Therefore, it will be necessary to include interventions in the treatment of OCD aimed at improving residual deficits in psychosocial functioning and QoL.
authors.affiliation: Department of Psychiatry, University of Leipzig, Johannisallee 20, 04317, Leipzig, Germany. stenglk@medizin.uni-leipzig.de
authors.forename: Katarina
authors.initials: K
authors.lastname: Stengler-Wenzke
authors.forename: Michael
authors.initials: M
authors.lastname: Kroll
authors.forename: Herbert
authors.initials: H
authors.lastname: Matschinger
authors.forename: Matthias C
authors.initials: MC
authors.lastname: Angermeyer
mesh_terms: D000293:Adolescent; D000328:Adult; D002391:Catchment Area, Health; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D012559:Schizophrenia / Q000453:epidemiology; D011795:Surveys and Questionnaires