[Immunohistochemical study of heme oxygenase-1 expressed in human normal dental pulp cell and tissue].
OBJECTIVE
To study the expression of heme oxygenase-1 (HO-1) in dental pulp tissue and to find out the relationship of distribution and function of HO-1.


METHODS
30 pulp tissues were obtained from clinically extracted human healthy premolars and third molars. The expression of HO-1 in dental pulp was detected by means of SABC immunohistochemical technology.


RESULTS
HO-1 immunoreactivity was observed in vascular endothelial cells, odontoblasts and some fibroblasts cells.


CONCLUSIONS
The distribution of HO-1 in normal human dental pulp suggests that HO-1 may play an important role in pulp flow regulation, dentin production and its calcifying; it also may play some roles in dental pulp cells metabolism and differentiation.
Yang
Fan
F
Dept. of Stomatology, Medical College of Zhejiang University, Hangzhou 310006, China.
Hu
Zhen-Yu
ZY
Fang
Hao
H
Cao
Zhi-Qiang
ZQ
D002454:Cell Differentiation; D003782:Dental Pulp; D003804:Dentin; D005347:Fibroblasts; D051547:Heme Oxygenase-1; D006801:Humans; D009804:Odontoblasts
D051547:Heme Oxygenase-1