title: Effect of corazonin and crustacean cardioactive peptide on heartbeat in the adult American cockroach (Periplaneta americana).
abstract: Changes in the frequency of cardiac pulsations have been monitored in the decapitated body of adult P. americana before and 5 h after the injections of [Arg(7)]-corazonin and CCAP, using newly invented touch-free, noninvasive optocardiographic methods. Relatively large dosages of these peptides (10(-6) M concentrations in the body) had no effect on the rate of the heartbeat beyond the Ringer control limits. It has been concluded, therefore, that Corazonin and CCAP, which are currently cited in the literature as "the most potent cardiostimulating peptides" in insects, have no effect on the physiological regulation of cardiac functions in the living body.
authors.affiliation: Institute of Entomology, Czech Academy of Sciences, Praha, Czech Republic. slama@entu.cas.cz
authors.forename: Karel
authors.initials: K
authors.lastname: Sláma
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Sakai
authors.forename: Makio
authors.initials: M
authors.lastname: Takeda
mesh_terms: D000818:Animals; D004562:Electrocardiography / Q000295:instrumentation / Q000379:methods / Q000662:veterinary; D005260:Female; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D019476:Insect Proteins / Q000494:pharmacology*; D008297:Male; D009479:Neuropeptides / Q000494:pharmacology*; D055095:Optics and Photonics / Q000295:instrumentation; D010526:Periplaneta / Q000187:drug effects* / Q000502:physiology*; D013997:Time Factors
chemical_list: D019476:Insect Proteins; D009479:Neuropeptides; C058620:crustacean cardioactive peptide; C060602:corazonin protein, insect