title: Immunosuppression and GB virus C-RNA detection among HIV-infected patients in Cambodia.
abstract: In this survey, 213 patients in an antiretroviral treatment programme in Phnom Penh, Cambodia, were tested for GB virus C (GBV-C) RNA before treatment initiation. Most had advanced HIV infection, only 34 having CD4 cell counts > 200 cells/microl. GBV-C-RNA was detected in 35 patients. The proportion with positive GBV-C-RNA decreased dramatically with CD4 cell counts < 100 cells/microl. In multivariate analysis, low CD4 cell counts, tuberculosis, anaemia, and traditional medicine were independently and negatively associated with GBV-C-RNA detection.
authors.affiliation: Institut Pasteur de Dakar, Dakar, Senegal.
authors.forename: Amadou A
authors.initials: AA
authors.lastname: Sall
authors.forename: Olivier
authors.initials: O
authors.lastname: Ségéral
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Reynes
authors.forename: Sreyrath
authors.initials: S
authors.lastname: Lay
authors.forename: Vara
authors.initials: V
authors.lastname: Ouk
authors.forename: Chan Roeun
authors.initials: CR
authors.lastname: Hak
authors.forename: Cheng Lay
authors.initials: CL
authors.lastname: Keo
authors.forename: Robin R
authors.initials: RR
authors.lastname: Lefait
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Delfraissy
authors.forename: Arnaud
authors.initials: A
authors.lastname: Fontanet
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D018178:Flaviviridae Infections / Q000276:immunology*; D029407:GB virus C / Q000302:isolation & purification*; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood; D012307:Risk Factors
chemical_list: D012367:RNA, Viral