title: Virulence factors and resistance mechanisms of Serratia marcescens. A short review.
abstract: Serratia marcescens, a Gram-negative bacillus that belongs to the family Enterobacteriaceae, is a human opportunistic pathogen bacterium that causes many diseases, such as urinary tract infections, respiratory tract infections, bacteremia, conjunctivitis, endocarditis, meningitis and wound infections. Many plasmides that confers multi-drug resistance were discovered, such as virulence factors, like cytotoxins that damage epithelial cells. The main topic of this paper presents a review about the molecular traits evolved in the pathogenic processes mediated by Serratia and its mechanism of resistance to drugs.
authors.affiliation: Faculdade de Medicina de Juazeiro do Norte, FMJ Ceará, Brazil.
authors.forename: Ana P
authors.initials: AP
authors.lastname: Rodrigues
authors.forename: A R M
authors.initials: AR
authors.lastname: Holanda
authors.forename: G P
authors.initials: GP
authors.lastname: Lustosa
authors.forename: S M B
authors.initials: SM
authors.lastname: Nóbrega
authors.forename: Willma J
authors.initials: WJ
authors.lastname: Santana
authors.forename: Luciana B S
authors.initials: LB
authors.lastname: Souza
authors.forename: H D M
authors.initials: HD
authors.lastname: Coutinho
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D017494:Proton Pumps; D016868:Serratia Infections / Q000382:microbiology; D012706:Serratia marcescens / Q000187:drug effects* / Q000378:metabolism*; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D000890:Anti-Infective Agents; D017494:Proton Pumps; D037521:Virulence Factors