title: Adenocarcinoma involving the uterine cervix: magnetic resonance imaging findings in tumours of endometrial, compared with cervical, origin.
abstract: OBJECTIVE
  To determine the distinctive magnetic resonance imaging (MRI) features of cervical and endometrial adenocarcinoma that present clinically as a cervical mass.
  
  
  METHODS
  From 1999 to 2002, 56 patients with adenocarcinoma on the initial biopsy of a cervical mass underwent MRI at our institution. Of these, 42 had a visible mass on MRI. Pathology review of all available tissue was the reference standard. A site of origin was determined by the pathologist in 38 of the 42 patients, and these were the cases evaluated; of these patients, 32 cases had adenocarcinoma and 6 had adenosquamous cancers.
  
  
  RESULTS
  Findings were significantly more prevalent in patients with adenocarcinomas of endometrial, compared with cervical, origin for endometrial thickening (11 [73%] and 3 [13%], respectively; P = 0.0003), endometrial mass (11 [73%] and 1 [4%], respectively; P < 0.0001), endometrial cavity expansion by a mass (9 [60%] and 2 [9%], respectively; P = 0.001), and invasion of myometrium from endometrium (9 [60%] and 0, respectively; P < 0.0001).
  
  
  CONCLUSIONS
  Adenocarcinomas of the endometrium that involve the cervix have MRI features that help distinguish them from primary adenocarcinomas of the cervix.
authors.affiliation: Department of Medical Imaging, University Health Network, Mount Sinai Hospital, University of Toronto, Toronto, ON. m.haider@utoronto.ca
authors.forename: Masoom A
authors.initials: MA
authors.lastname: Haider
authors.forename: Michael
authors.initials: M
authors.lastname: Patlas
authors.forename: Kartik
authors.initials: K
authors.lastname: Jhaveri
authors.forename: William
authors.initials: W
authors.lastname: Chapman
authors.forename: Anthony
authors.initials: A
authors.lastname: Fyles
authors.forename: Barry
authors.initials: B
authors.lastname: Rosen
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D018196:Carcinoma, Adenosquamous / Q000175:diagnosis / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012015:Reference Standards; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery