title: Inhibitory effect of polar oregano extracts on aldose reductase and soybean lipoxygenase in vitro.
abstract: The effect of methanol and aqueous methanol extract of Origanum vulgare L. ssp. hirtum on aldose reductase and soybean lipoxygenase was investigated. The results revealed a promising potential of oregano for preventing diabetes complications in the long term and an antiinflammatory efficacy by inhibiting soybean lipoxygenase.
authors.affiliation: Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece.
authors.forename: Catherine
authors.initials: C
authors.lastname: Koukoulitsa
authors.forename: Chariklia
authors.initials: C
authors.lastname: Zika
authors.forename: Dimitra
authors.initials: D
authors.lastname: Hadjipavlou-Litina
authors.forename: Vassilis J
authors.initials: VJ
authors.lastname: Demopoulos
authors.forename: Helen
authors.initials: H
authors.lastname: Skaltsa
mesh_terms: D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D008084:Lipoxygenase / Q000378:metabolism*; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology*; D000432:Methanol / Q000737:chemistry; D031341:Origanum / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010940:Plant Proteins / Q000737:chemistry / Q000494:pharmacology; D013025:Glycine max / Q000201:enzymology*
chemical_list: D016859:Lipoxygenase Inhibitors; D010936:Plant Extracts; D010940:Plant Proteins; D000449:Aldehyde Reductase; D008084:Lipoxygenase; D000432:Methanol