Loss-of-function alleles of the JIL-1 kinase are strong suppressors of position effect variegation of the wm4 allele in Drosophila.
In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the wm4 allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer Evar2-1 on PEV.
Lerach
Stephanie
S
Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Zhang
Weiguo
W
Bao
Xiaomin
X
Deng
Huai
H
Girton
Jack
J
Johansen
Jørgen
J
Johansen
Kristen M
KM
D000483:Alleles; D000818:Animals; D004330:Drosophila; D029721:Drosophila Proteins / Q000235:genetics*; D005799:Genes, Dominant; D016153:Genes, Suppressor; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*
D029721:Drosophila Proteins; C507306:JIL-1 protein, Drosophila; D017346:Protein Serine-Threonine Kinases