Enantioselective hydrogenation of acyclic aromatic N-aryl imines catalyzed by an iridium complex of (S,S)-1,2-bis(tert-butylmethylphosphino)ethane.
[reaction: see text] An iridium(I) complex of (S,S)-1,2-bis(tert-butylmethylphosphino)ethane with tetrakis(3,5-bis(trifluoromethyl)phenyl)borate as the counterion catalyzes the hydrogenation of acyclic aromatic N-aryl imines under 1 atm of hydrogen pressure at room temperature to give the corresponding optically active secondary amines with up to 99% ee.
Imamoto
Tsuneo
T
Department of Chemistry, Faculty of Science, Chiba University, Yayoi-cho, Inage-ku, Japan. imamoto@faculty.chiba-u.jp
Iwadate
Noriyuki
N
Yoshida
Kazuhiro
K