Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model.
Because of their physicochemical properties and the selective receptor-mediated uptake of their core components, reconstituted high-density lipoproteins have unique advantages over conventional formulations to serve as targeted drug delivery agents.
Lacko
Andras G
AG
University of North Texas Health Science Center, Fort Worth, Tex. 76107-2699, USA. alacko@hsc.unt.edu
Nair
Maya
M
Paranjape
Sulabha
S
Mooberry
Linda
L
McConathy
Walter J
WJ
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D016503:Drug Delivery Systems; D006801:Humans; D008075:Lipoproteins, HDL / Q000008:administration & dosage*; D049329:Nanostructures; D009369:Neoplasms / Q000188:drug therapy
D000970:Antineoplastic Agents; D008075:Lipoproteins, HDL