title: New Ca2+ indicator has freedom to express.
abstract: In this issue of Chemistry & Biology, Tsien and colleagues describe a new family of highly sensitive genetically encoded calcium biosensors that are not affected by their local environment and can measure calcium concentration over a wide dynamic range.
authors.affiliation: Department of Pharmacology, University of Cambridge, United Kingdom.
authors.forename: H Llewelyn
authors.initials: HL
authors.lastname: Roderick
authors.forename: Martin D
authors.initials: MD
authors.lastname: Bootman
mesh_terms: D002118:Calcium / Q000737:chemistry*; D002614:Chelating Agents / Q000737:chemistry*; D049452:Green Fluorescent Proteins / Q000737:chemistry
chemical_list: D002614:Chelating Agents; D049452:Green Fluorescent Proteins; D002118:Calcium