title: [A case of secondary amyloidosis presenting as massive gastrointestinal bleeding].
abstract: Amyloidosis is a disorder characterized by extracellular deposition of amyloid in various tissues and organs. Gastrointestinal manifestations including gastroparesis, constipation, malabsorption, intestinal pseudo-obstruction, and bleeding are common. GI bleeding is a rare initial symptom which can be fatal in some cases. Absence of systemic symptoms and nonspecific endoscopic findings in amyloidosis may make diagnosis difficult. Therefore, amyloidosis-induced GI bleeding should be considered in patients with an obscure hemorrhage. Recently, we experienced a 65-year-old woman who presented with massive hematochezia as a manifestations of amyloidosis. Colonoscopy and SMA angiography showed massive bleeding in the small and large intestine. Colonoscopic biopsy established amyloidosis. We report this case with a review of the relevant literatures.
authors.affiliation: Department of Internal Medicine, Inje University College of Medicine, Paik Hospital, Busan, Korea.
authors.forename: Hee
authors.initials: H
authors.lastname: Kim
authors.forename: Sam Ryong
authors.initials: SR
authors.lastname: Jee
authors.forename: Sang Bong
authors.initials: SB
authors.lastname: Lee
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Lee
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Park
authors.forename: Eun Taek
authors.initials: ET
authors.lastname: Park
authors.forename: Yeon Jae
authors.initials: YJ
authors.lastname: Lee
authors.forename: Sang Hyuk
authors.initials: SH
authors.lastname: Lee
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Seol
authors.forename: Jung Myung
authors.initials: JM
authors.lastname: Chung
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications* / Q000175:diagnosis