title: [Soft tissue sarcoma--epidemiology, diagnosis and treatment].
abstract: On account of the considerable variability of the clinical situation, treatment of soft tissue sarcoma requires an individually oriented multimodal approach. In the case of patients with superficial low-grade tumors measuring less than 5 cm in diameter, resection alone is usually adequate. In the event of medium-grade lesions, resection with negative margins, resection in combination with radiotherapy achieves excellent local control rates associated with an overall survival rate of almost 80%. In patients with high-grade sarcomas measuring more than 5 cm in diameter, local control can be achieved with resection and radiotherapy, although every second such patient develops metastases. For patients with local recurrence, further resection should be considered/performed. Radiotherapy is all the more effective, the smaller the postoperative tumor cell burden.
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, TU München. h.rechl@lrz.tu-muenchen.de
authors.forename: H
authors.initials: H
authors.lastname: Rechl
authors.forename: K
authors.initials: K
authors.lastname: Wörtler
authors.forename: G
authors.initials: G
authors.lastname: Weirich
authors.forename: K
authors.initials: K
authors.lastname: Specht
authors.forename: R
authors.initials: R
authors.lastname: Gradinger
mesh_terms: D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D051677:Histiocytoma, Malignant Fibrous / Q000175:diagnosis; D006801:Humans; D015994:Incidence; D008080:Liposarcoma / Q000175:diagnosis; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012509:Sarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy; D013584:Sarcoma, Synovial / Q000175:diagnosis