title: Disseminated mycobacterium bovis infection in an immunocompetent host.
abstract: We report about a rare case of disseminated Mycobacterium bovis infection in a 61 year old female immunocompetent patient with involvement of the lung, the brain, the spleen and spine. The patient had intracerebral tuberculomas with paradoxical enlargement during the first weeks of therapy. We reviewed the data of our microbiological department and found five other patients with Mycobacterium bovis infection diagnosed between 1999 and 2004, which are 5.8 % of all diagnoses of tuberculosis during this period.
authors.affiliation: Department of Internal Medicine III, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany. n.schuebel@gmx.de
authors.forename: Niels
authors.initials: N
authors.lastname: Schübel
authors.forename: J
authors.initials: J
authors.lastname: Rupp
authors.forename: S
authors.initials: S
authors.lastname: Gottschalk
authors.forename: P
authors.initials: P
authors.lastname: Zabel
authors.forename: K
authors.initials: K
authors.lastname: Dalhoff
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000382:microbiology*; D001921:Brain / Q000382:microbiology / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009163:Mycobacterium bovis / Q000276:immunology / Q000302:isolation & purification*; D016896:Treatment Outcome; D016862:Tuberculoma, Intracranial / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D014376:Tuberculosis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
chemical_list: D000995:Antitubercular Agents; D005938:Glucocorticoids