Cyclic oligomers of oxetane-based dipeptide isosteres derived from L-rhamnose.
Two new cyclic oligomers, cyclo-tetra-[2,4-anhydro-3-O-tert-butyldimethylsilyl-5-deoxy-L-rhamnonamido-(N-->5)] and the corresponding 6-deoxy-D-gulonate cyclic "tetramer", have been synthesised from linear tetrameric oligomers, using TBTU- and pentafluorophenyl ester-based methodologies, respectively. These two compounds constitute a novel class of cyclic oligomers derived from oxetane-based sugar amino acids.
Fleet
George W J
GW
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
Johnson
Stephen W
SW
Jones
John H
JH
D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D004988:Ethers, Cyclic / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D012210:Rhamnose / Q000737:chemistry*; D013237:Stereoisomerism
D004151:Dipeptides; D004988:Ethers, Cyclic; D007202:Indicators and Reagents; C005287:oxetane; D012210:Rhamnose