Rosai-Dorfman disease with cutaneous manifestation (sinus histiocytosis with massive lymphadenopathy).
We report a 73-year-old woman with the typical findings of "Rosai-Dorfman disease" (RDD) including massive, painless lymphadenopathy, fever and multiple, asymptomatic cutaneous lesions on her face, collum and neck. Histologically, the lesions were marked by characteristic large macrophages exhibiting emperipolesis.
Coras
Brigitte
B
Department of Dermatology, University of Regensburg, Germany.
Michel
Susanne
S
Landthaler
Michael
M
Hohenleutner
Ulrich
U
D000368:Aged; D001706:Biopsy; D005260:Female; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D012871:Skin Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D014463:Ultrasonography