title: Novel phloroglucinol derivatives from the roots of Lysidice rhodostegia.
abstract: [structure: see text] Three novel phloroglucinol derivatives of lysidicins A-C (1-3) have been isolated from the roots of Lysidice rhodostegia and structures were elucidated by comprehensive NMR and MS spectroscopic analysis. 1 and 2 possess spirocyclic benzodihydrofuran skeleton. Their relative stereochemistries were assigned by NOE or NOESY experiment. A plausible pathway for the biosynthesis of 1-3 from 4 and a ketose derivative was postulated.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Beijing, People's Republic of China.
authors.forename: You-cai
authors.initials: YC
authors.lastname: Hu
authors.forename: Xian-fu
authors.initials: XF
authors.lastname: Wu
authors.forename: Song
authors.initials: S
authors.lastname: Gao
authors.forename: Shi-Shan
authors.initials: SS
authors.lastname: Yu
authors.forename: Yue
authors.initials: Y
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Qu
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Yun-bao
authors.initials: YB
authors.lastname: Liu
mesh_terms: D007887:Fabaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010696:Phloroglucinol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: C518048:lysidicin A; C518049:lysidicin B; C518050:lysidicin C; D010696:Phloroglucinol