title: Total hip replacement in patients with severe bleeding disorders. A 30 years single center experience.
abstract: Arthropathy of the hip is moderate in frequency in haemophiliac patients, but is less common than ankle, knee or elbow arthropathy. We report about our experience with total hip replacement in patients with severe bleeding disorders over a period of 30 years. Between July 1972 and 2002, 15 hips in 13 patients were replaced. The main bleeding disorders were Haemophilia A in ten patients and severe v. Willebrand disease in three patients. The mean follow-up was 132 months (range 12-363). We can demonstrate good long-term results, with only one aseptic loosening after 14 years and one septic loosening after 14 months in an HIV-positive patient. The Harris Hip Score increased from 48 points (32-66) preoperatively to 89 (76-100) postoperatively. In conclusion, total hip replacement performed in a specialised haemophiliac centre is a safe procedure, and results in pain relief and improvement of the quality of life in patients with severe bleeding disorders.
authors.affiliation: Department of Orthopaedic Surgery, University Hospital Frankfurt/Main, Marienburgstrasse 2, 60528, Frankfurt/Main, Germany. B.Habermann@Friedrichsheim.de
authors.forename: B
authors.initials: B
authors.lastname: Habermann
authors.forename: C
authors.initials: C
authors.lastname: Eberhardt
authors.forename: L
authors.initials: L
authors.lastname: Hovy
authors.forename: L
authors.initials: L
authors.lastname: Zichner
authors.forename: I
authors.initials: I
authors.lastname: Scharrer
authors.forename: A A
authors.initials: AA
authors.lastname: Kurth
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D016063:Blood Loss, Surgical; D006467:Hemophilia A / Q000150:complications* / Q000601:surgery; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D011788:Quality of Life; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome; D014842:von Willebrand Diseases / Q000150:complications* / Q000601:surgery