Serum creatinine as a predictor of transplant survival and death.
Taking ALL patients transplanted in a given calendar year, we have shown that serum creatinine values have gradually decreased over the past 15 years. Donor age was a major factor influencing serum creatinine. This was followed by the recipient sex. Of lesser importance was the different immunosuppressive drugs employed, and whether the donor was deceased or living. The strong predictive value of serum creatinine was shown at various times after transplantation. Also, one year prior to failure, the creatinine values were very significantly elevated. A similar finding was noted one year prior to the death of patients with a functioning graft.
Mizutani
Kazuo
K
Terasaki Foundation Laboratory, Los Angeles, California, USA.
Terasaki
Paul
P
D000328:Adult; D000367:Age Factors; D065095:Calcineurin Inhibitors; D003404:Creatinine / Q000097:blood*; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality / Q000502:physiology*; D008875:Middle Aged; D011379:Prognosis; D015996:Survival Rate; D013997:Time Factors; D014019:Tissue Donors; D014481:United States / Q000453:epidemiology
D065095:Calcineurin Inhibitors; D003404:Creatinine