[An experimental research on different temperature sintered bone as carrier of bone morphogenetic protein].
This study was conducted to find perfect temperature sintered bone as carrier of bone morphogenetic protein (BMP). The different temperature active sintered bones, which were made up of calcine bone and bone morphogenetic protein, were implanted into the defects of rabbit radius. Compared with the sintered bone of 600 degrees C, the sintered bone of 900 degrees C and 1200 degrees C could induce more pieces of bone formation and be replaced by new bone. There were more pieces of new bone formation in sintered bone of 900 degrees C and 1200 degrees C than those in sintered bone of 600 degrees C (P<0.05). There was no difference between the sintered bone of 900 degrees C and 1 200 degrees C (P>0.05). In comparison with the sintered bone of 600 degrees C and 1200 degrees C, the sintered bone of 900 degrees C may be the choicest carrier of bone morphogenetic protein.
Zang
Hongmin
H
Department of Orthopedics, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China. zhm197@hotmail.com
Liu
Yiheng
Y
Chen
Junchang
J
Wang
Kunzheng
K
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000737:chemistry*; D001842:Bone and Bones / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D005260:Female; D006358:Hot Temperature; D008297:Male; D011817:Rabbits; D013696:Temperature
D019485:Bone Morphogenetic Proteins; D004337:Drug Carriers