[Interferential effect of ligustrazine injection on lymph circulation during the recovery of hemorrhagic shock in rats].
OBJECTIVE
To explore effects of ligustrazine injection (LI) on lymph circulation during the recovery of heamoregic shock.


METHODS
Effects of LI on lymph circulation were observed and determined in 16 Wistar rats by lymphatology methods.


RESULTS
During hemorrhagic shock, the intestinal lymph flux, lymphocytes out put was obviously decreased, and there was little monocytes in the lymph fluid, but the lymph fluid viscosity was increased. After treatment of LI, the intestinal lymph flux, lymphocytes out put was obviously increased, and there was a lot of monocytes in the lymph fluid. There were significant difference compared with control group (P < 0.01). Besides, LI could make the lymph fluid viscosity decrease and the effect was strong than that of control group (P < 0.01).


CONCLUSIONS
LI can intervene the recovery of heamoregic shock through enhaning the transport function of lymph circulation, the number of lymphocytes and monocytes, and decreasing lymph fluid viscosity.
Liu
Yan-Kai
YK
Hebei North University, Zhangjiakou 075029, China.
Zhang
Xiao-Yun
XY
Jiang
Hua
H
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007267:Injections; D008208:Lymphatic System / Q000503:physiopathology*; D008214:Lymphocytes / Q000187:drug effects; D009000:Monocytes / Q000187:drug effects; D011719:Pyrazines / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012771:Shock, Hemorrhagic / Q000473:pathology* / Q000503:physiopathology; D014665:Vasodilator Agents / Q000494:pharmacology
D004365:Drugs, Chinese Herbal; D011719:Pyrazines; D014665:Vasodilator Agents; C017953:tetramethylpyrazine