Bone marrow dose estimates from work-related medical x-ray examinations given between 1943 and 1966 for personnel from five U.S. nuclear facilities.
Inclusion of dose from work-related medical x-ray examinations with occupational external dose in an epidemiological study may reduce misclassification of exposures and provide more accurate assessment of leukemia risk from occupational exposure to ionizing radiation. In a multi-site leukemia case-control study, annual bone marrow doses due to work-related x-ray examinations given between 1943 and 1966 were estimated for cases and controls employed at five nuclear facilities. Only active bone marrow dose from photofluorographic chest and routine lumbar spine x rays were included. Bone marrow dose assigned for a single exposure ranged from 1.0 to 1.4 mGy. Mean and median cumulative bone marrow doses for each of the five sites from work-related x-ray examinations ranged from 2.0 to 14 mGy and 2.1 to 8.8 mGy, respectively. Results suggest that bone marrow dose from work-related photofluorographic and lumbar spine x-ray examinations given during the time period of this study may be significant compared to occupational bone marrow dose.
Anderson
Jeri L
JL
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, PHS/DHHS, 4676 Columbia Pkwy, Mail Stop R-44, Cincinnati, OH 45226, USA.
Daniels
Robert D
RD
D001822:Body Burden; D001853:Bone Marrow; D006801:Humans; D009688:Nuclear Reactors / Q000706:statistics & numerical data*; D016273:Occupational Exposure / Q000032:analysis*; D011210:Power Plants / Q000706:statistics & numerical data*; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods*; D011859:Radiography / Q000706:statistics & numerical data*; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014481:United States / Q000453:epidemiology