title: Multiple eyelid defects in cutaneous Langerhans cell histiocytosis.
abstract: Langerhans cell histiocytosis is a disorder characterized by the proliferation of histiocytes of the mononuclear phagocyte system. Cutaneous Langerhans cell histiocytosis can develop as a solitary lesion or more frequently as part of a multisystem disease. This report describes a case of cutaneous Langerhans cell histiocytosis affecting the eyelids, resulting in a coloboma-like defect. The clinical features and management are discussed.
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong SAR, People's Republic of China. watsk1@hotmail.com
authors.forename: Christina S K
authors.initials: CS
authors.lastname: Wat
authors.forename: Hunter K L
authors.initials: HK
authors.lastname: Yuen
authors.forename: K K
authors.initials: KK
authors.lastname: Tse
authors.forename: Dennis S C
authors.initials: DS
authors.lastname: Lam
authors.forename: Nongnart
authors.initials: N
authors.lastname: Chan
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007801:Langerhans Cells / Q000473:pathology; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology / Q000628:therapy
chemical_list: D005938:Glucocorticoids