Vertebrate segmentation: snail counts the time until morphogenesis.
During segmentation of vertebrate embryos, unsegmented mesenchymal mesoderm is divided into epithelial segments called somites. This process is governed by oscillating gene expression of the somite clock. A recent paper identifies the transcription factor Snail as a link between the somite clock and the control of somite morphogenesis.
Holley
Scott A
SA
Department of Molecular, Cellular and Developmental Biology, Yale University, P.O. Box 208103, New Haven, Connecticut 06520, USA. scott.holley@yale.edu
D000818:Animals; D001683:Biological Clocks; D002642:Chick Embryo; D051379:Mice; D009024:Morphogenesis / Q000235:genetics*; D000071250:Snail Family Transcription Factors; D019170:Somites; D014157:Transcription Factors / Q000502:physiology*; D014714:Vertebrates / Q000196:embryology / Q000254:growth & development*
D000071250:Snail Family Transcription Factors; D014157:Transcription Factors