title: Recent developments and future prospects in insect pest control in transgenic crops.
abstract: The adoption of insect-resistant transgenic crops has been increasing annually at double-digit rates since the commercial release of first-generation maize and cotton expressing a single modified Bacillus thuringiensis toxin (Bt) nine years ago. Studies have shown that these Bt crops can be successfully deployed in agriculture, which has led to a decrease in pesticide usage, and that they are environmentally benign. However, the sustainability and durability of pest resistance continues to be discussed. In this review, we focus on the science that underpins second- and third-generation insect-resistant transgenic plants and examine the appropriateness and relevance of models that are currently being used to determine deployment strategies to maximize sustainability and durability. We also review strategies that are being developed for novel approaches to transgenic insect pest control.
authors.affiliation: ICREA, Universitat de Lleida, PVCF, Av Alcalde Rovira Roure, 191, E-25198, Lleida, Spain. paul.christou@icrea.es
authors.forename: Paul
authors.initials: P
authors.lastname: Christou
authors.forename: Teresa
authors.initials: T
authors.lastname: Capell
authors.forename: Ajay
authors.initials: A
authors.lastname: Kohli
authors.forename: John A
authors.initials: JA
authors.lastname: Gatehouse
authors.forename: Angharad M R
authors.initials: AM
authors.lastname: Gatehouse
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics / Q000378:metabolism; D004198:Disease Susceptibility; D007300:Insect Control / Q000639:trends*; D008954:Models, Biological; D030821:Plants, Genetically Modified / Q000235:genetics / Q000469:parasitology*
chemical_list: C049673:Bacillus thuringiensis ovicidal toxin; D001427:Bacterial Toxins