[Heart fatty-acid binding protein (h-FABP): a new cardiac marker].
Heart Fatty-Acid Binding Protein (h-FABP) is a small cytosolic protein that is abundant in the heart and found at lower concentrations in muscle or in the brain. h-FABP is released into the circulation shortly after the onset of ischemia. Several studies indicate its usefulness in cardiology: exclusion of acute myocardial infarction, detection of reperfusion, prognostic value... A rapid immuno-chromatographic assay (Cardiodetect) was recently commercialized in France with a result obtainable within 15 minutes. We review the strengths and weakness of h-FABP for detecting myocardial injury.
Servonnet
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Laboratoire de biochimie, pharmacologie, toxicologie cliniques, Hôpital d'Instruction des Armées Robert Picqué, Villenave d'Ornon. a_servonnet@yahoo.fr
Delacour
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H
Dehan
C
C
Gardet
V
V
D015415:Biomarkers / Q000097:blood; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D006331:Heart Diseases / Q000097:blood*; D006801:Humans
D015415:Biomarkers; C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins