title: Parkinson's disease and dementia.
abstract: Parkinson's disease (PD) is one of the most common neurodegenerative disorders, affecting about 1% of the population over the age of 60. In addition to motor abnormalities, there are several non-motor signs and symptoms that may create a considerable burden for patients and care-givers. Dementia is common and affects approximately 40% of PD patients during the course of the disease, the risk for the development of dementia being 6 times higher than in non-PD age-matched controls. In most cases, PD patients with dementia (PDD) display a dysexecutive syndrome and visuospatial deficits, while memory is relatively unaffected. The overlap between PDD and dementia with Lewy bodies suggests that they likely share similar underlying neuropathological processes.
authors.affiliation: Department Medical and Surgical Sciences, Institute of Neurology, University of Brescia, P.zza Spedali Civili 1, I-25125 Brescia, Italy. padovani@med.unibs.it
authors.forename: A
authors.initials: A
authors.lastname: Padovani
authors.forename: C
authors.initials: C
authors.lastname: Costanzi
authors.forename: N
authors.initials: N
authors.lastname: Gilberti
authors.forename: B
authors.initials: B
authors.lastname: Borroni
mesh_terms: D003704:Dementia / Q000145:classification / Q000150:complications* / Q000473:pathology; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000473:pathology; D012306:Risk