title: The ASSR: clinical application in normal-hearing and hearing-impaired infants and adults, comparison with the click-evoked ABR and pure-tone audiometry.
abstract: The objective of this study was to investigate the clinical application of the ASSR (GSI Audera). It was completed in two parts: Study 1. Correlation between the ASSR-based threshold estimations and the conventional pure-tone thresholds in adults; and Study 2. Correlation between the average of the 2-4 kHz ASSR-based threshold estimations and c-ABR thresholds in children. The ASSRs were recorded in awake adults and sleeping infants with a range of hearing loss at CFs of 0.5 to 4 kHz and MFs between 46 and 95 Hz. The results show that in hearing-impaired adults (thresholds > 40 dBHL) good correlations can be observed between the behavioural thresholds and the ASSR-based threshold estimations. For the normal- to near-normal-hearing adults, a significant correspondence exists between the ASSR-based threshold estimations and FPTA. In children, strong correlations were found between the c-ABR and the 2-4 kHz ASSR-based threshold estimation average. These studies illustrate that the GSI Audera ASSR can accurately predict the behavioural audiogram in hearing-impaired subjects. In subjects with normal hearing the individual ASSR-based threshold estimations scatter too much. Instead the average of the ASSR-based threshold estimations corresponds well with the FPTA.
authors.affiliation: Antwerp University Hospital, Department of Otolaryngology, Edegem, Belgium. Fanny.Scherf@uza.be
authors.forename: Fanny
authors.initials: F
authors.lastname: Scherf
authors.forename: Jan
authors.initials: J
authors.lastname: Brokx
authors.forename: Floris L
authors.initials: FL
authors.lastname: Wuyts
authors.forename: Paul H
authors.initials: PH
authors.lastname: Van de Heyning
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001300:Audiometry, Evoked Response / Q000379:methods*; D001301:Audiometry, Pure-Tone / Q000379:methods*; D001309:Auditory Threshold; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis