title: Disseminated spread of recurrent oligodendroglioma (WHO grade II).
abstract: Oligodendroglioma is a relatively uncommon primary brain tumour. The occurrence of metastatic dissemination of oligodendroglioma is rare and usually occurs in patients with anaplastic oligodendroglioma. The dissemination of WHO Grade II oligodendroglioma can occur and we report a patient with an initial diagnosis of a left temporal oligodendroglioma who presented with disseminated disease in the left temporal lobe, sellar region, medulla oblongata, both frontal lobes and ventricles more than 8 years later. Histology at dissemination showed anaplastic oligodendroglioma. Similar reports of metastatic dissemination of oligodendrogliomas reveal that the tumours may remain as WHO Grade II or may progress to anaplastic oligodendroglioma at metastasis. However, regardless of the histological grade at metastasis, the prognosis of metastatic oligodendroglioma is poor.
authors.affiliation: Department of Neurosurgery, National Neuroscience Institute, Singapore, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore. wai_hoe_ng@nni.com.sg
authors.forename: Wai Hoe
authors.initials: WH
authors.lastname: Ng
authors.forename: Tchoyoson C C
authors.initials: TC
authors.lastname: Lim
authors.forename: Kheng Kooi
authors.initials: KK
authors.lastname: Tan
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D009837:Oligodendroglioma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D011859:Radiography