Heterogeneity among Mycobacterium ulcerans isolates from Africa.
Mycobacterium ulcerans causes Buruli ulcer, an ulcerative skin disease in tropical and subtropical areas. Despite restricted genetic diversity, mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis on M. ulcerans revealed 3 genotypes from different African countries. It is the first time this typing method succeeded directly on patient samples.
Stragier
Pieter
P
Department of Microbiology, Mycobacteriology Unit, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Ablordey
Anthony
A
Bayonne
L Manou
LM
Lugor
Yatta L
YL
Sindani
Ireneaus S
IS
Suykerbuyk
Patrick
P
Wabinga
Henry
H
Meyers
Wayne M
WM
Portaels
Françoise
F
D000349:Africa / Q000453:epidemiology; D015373:Bacterial Typing Techniques; D001483:Base Sequence; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009165:Mycobacterium Infections, Nontuberculous / Q000453:epidemiology / Q000382:microbiology*; D019911:Mycobacterium ulcerans / Q000145:classification* / Q000235:genetics*; D010802:Phylogeny; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences