Hypoglycemic effect of Bauhinia cheilandra in rats.
The extract of the methanolic leaves of Bauhinia cheilandra (BC) was tested on glucose loaded and alloxan-induced diabetic rats. In both tests, the methanolic extract at doses of 300, 600, and 900 mg/kg, has shown a statistically significant and considerable hypoglycemic activity.
Almeida
E R
ER
Laboratório de Farmacologia do Departamento de Antibiótico, Universidade Federal de Pernambuco CEP 50670-901 Recife, PE, Brazil. ealmeida@ufpe.br
Guedes
M C
MC
Albuquerque
J F C
JF
Xavier
H
H
D000284:Administration, Oral; D000496:Alloxan; D000818:Animals; D036481:Bauhinia; D001786:Blood Glucose / Q000187:drug effects*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000496:Alloxan