title: [Familial precocious puberty -- a variant of norm or pathology?].
abstract: Since 1937, when familial precocious puberty (FPP) was described for the first time, only few reports on FPP have been published. The majority of them is concerned with the most investigated form of FPP, occurring only in male --testotoxicosis (male-limited precocious puberty -- MLPP). Recently another form of FPP -- familial hyperestrogenism (aromatase excess syndrome -- AES) has been described. The authors aimed to review the literature data concerning different forms of FPP emphasizing the diagnostic criteria, etiology, mode of inheritance and treatment.
authors.affiliation: Katedra i Klinika Pediatrii, Nefrologii i Endokrynologii Dzieciecej w Zabrzu Slaskiej AM w Katowicach, Katowice. endo_dz_zabrze@wp.pl
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Ziora
authors.forename: Joanna
authors.initials: J
authors.lastname: Oświecimska
authors.forename: Gabriela
authors.initials: G
authors.lastname: Geisler
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Broll-Waśka
authors.forename: Mieczysław
authors.initials: M
authors.lastname: Szalecki
authors.forename: Antoni
authors.initials: A
authors.lastname: Dyduch
mesh_terms: D000293:Adolescent; D001141:Aromatase / Q000378:metabolism; D002648:Child; D002657:Child Development; D004958:Estradiol / Q000378:metabolism; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006062:Gonadotropins / Q000378:metabolism; D006801:Humans; D008297:Male; D011629:Puberty, Precocious / Q000175:diagnosis* / Q000235:genetics* / Q000378:metabolism / Q000628:therapy; D013739:Testosterone / Q000378:metabolism
chemical_list: D012739:Gonadal Steroid Hormones; D006062:Gonadotropins; D013739:Testosterone; D004958:Estradiol; D001141:Aromatase