Subcutaneous fat necrosis of the newborn: be aware of hypercalcaemia.
Subcutaneous fat necrosis of the newborn is an uncommon, self-limiting panniculitis that usually occurs in full-term infants as a consequence of perinatal asphyxia. The cutaneous involvement may be associated with metabolic complications such as hypoglycaemia, thrombocytopenia, hypertriglyceridemia, anemia and hypercalcaemia. The delayed onset of hypercalcaemia, 1-6 months after the development of the skin manifestations, imposes a prolonged follow-up to avoid its acute toxic effects on cardiovascular and renal systems and the more durable metastatic calcifications.
Borgia
Francesco
F
Institute of Dermatology, University Hospital G. Martino, Messina, Italy. ist.dermatologia@unime.it
De Pasquale
Loredana
L
Cacace
Caterina
C
Meo
Petronilla
P
Guarneri
Claudio
C
Cannavo
Serafinella P
SP
D001238:Asphyxia Neonatorum / Q000628:therapy; D005218:Fat Necrosis / Q000473:pathology*; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy; D007669:Kidney Calculi / Q000000981:diagnostic imaging; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D050151:Subcutaneous Fat / Q000473:pathology*; D014463:Ultrasonography
D005665:Furosemide; D011239:Prednisolone