[Activity of antioxidative ferments during obesity of different degree].
The purpose of our research was to define influence of dislipidemia on the redox-system, developed during obesity. 150 patients from 18 to 55 years were examined having obesity of a different degrees who have been admitted to the endocrinology department of 4-th clinical hospital of Tbilisi. On the basis of the analysis of the received data it is possible to conclude that with in a degree of obesity a deterioration of parameters of lipid exchange was observed which from its part exerts its influence on the redox-system of an organism. Namely, it promotes reduction of antioxidant protection system in comparison with the control group. Also, dependence of change of activity of antioxidant ferments on the age and intensity of lipid exchange has been revealed. Furthermore, it has been revealed that deterioration of lipid exchange in patients over 30 years is the reason for compensatory activity of antioxidant ferments (SOD and catalase).
Giorgadze
D D
DD
Giorgadze
E R
ER
Sanikidze
T V
TV
Papava
M B
MB
D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology*; D010084:Oxidation-Reduction; D012720:Severity of Illness Index
D000975:Antioxidants