title: Stereoelectronic effects on type I 1,2-dyotropic rearrangements in vicinal dibromides.
abstract: The effects of different substituents on type I-dyotropic rearrangements of open-chain and cyclic 1,2-dibromo hydrocarbons have been studied by means of DFT calculations. The activation energy (E(a)) of this transformation decreases with the pi-donor ability of the substituent attached to the reacting ethylenic system. This is due to donation of electronic density by conjugation or hyperconjugation. This donation leads to longer C--C and C--Br bond lengths in the corresponding four-membered transition states (TSs). Linear relationships between the E(a) and either the sigma(p) Hammett substituent constants and the C--C bond length of the TSs were also found. In all cases, the processes have a high value of synchronicity, which is mainly independent on the substituents. A model based on the second-order perturbational analysis for one ethylene unit with two apical bromine radicals accounts for all the computed results.
authors.affiliation: Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain. israel@quim.ucm.es
authors.forename: Israel
authors.initials: I
authors.lastname: Fernández
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Sierra
authors.forename: Fernando P
authors.initials: FP
authors.lastname: Cossío