title: [Gene mixture in a population sample from Buenos Aires City].
abstract: The aim of this study is to estimate the gene admixture in the population of Buenos Aires City from samples of blood donors, which come from a public health centre (Hospital de Clínicas). These studies were performed on 218 unrelated people, who donated blood during the year 2002. Eight erythrocyte genetic systems and GM/KM allotypes were analysed. A survey to obtain information about place of birth, present residence and genealogical data of the donors was performed. The gene frequencies were determined using a method of maximum likelihood. The genetic admixture was calculated through the ADMIX program (trihibride). The Amerindian and African contributions were 15.8% and 4.3% respectively. These data were compared with those obtained in a previous study performed in a private centre (Hospital Italiano de Buenos Aires) and significant differences were observed, except in the KM system. The results obtained are in concordance with the demographic and historic information of Buenos Aires City.
authors.affiliation: Sección Antropología Biológica, Instituto de Ciencias Antropológicas, Centro de Genética, Facultades de Filosofía y Letras y Ciencias Veterinarias, Universidad de Buenos Aires.
authors.forename: Sergio A
authors.initials: SA
authors.lastname: Avena
authors.forename: Alicia S
authors.initials: AS
authors.lastname: Goicoechea
authors.forename: Jorge
authors.initials: J
authors.lastname: Rey
authors.forename: Jean M
authors.initials: JM
authors.lastname: Dugoujon
authors.forename: Cristina B
authors.initials: CB
authors.lastname: Dejean
authors.forename: Francisco R
authors.initials: FR
authors.lastname: Carnese
mesh_terms: D000349:Africa / Q000208:ethnology; D001118:Argentina / Q000208:ethnology; D004641:Emigration and Immigration; D005060:Europe / Q000208:ethnology; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D005820:Genetic Testing; D005828:Genetics, Population; D006801:Humans; D007199:Indians, South American / Q000235:genetics; D008297:Male
chemical_list: D005819:Genetic Markers