Neural stem cells as novel cancer therapeutic vehicles.
The startling resemblance of many of the behaviours of brain tumours to the intrinsic properties of the neural stem/progenitor cell has triggered a recent dual interest in arming stem cells to track and help eradicate tumours and in viewing stem cell biology as somehow integral to the emergence and/or propagation of the neoplasm itself. These aspects are reviewed and discussed here.
Yip
Stephen
S
Department of Pathology & Laboratory Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
Sabetrasekh
Roya
R
Sidman
Richard L
RL
Snyder
Evan Y
EY
D001932:Brain Neoplasms / Q000628:therapy; D005544:Forecasting; D005910:Glioma / Q000628:therapy; D006801:Humans; D039902:Multipotent Stem Cells / Q000166:cytology; D009369:Neoplasms / Q000628:therapy*; D009474:Neurons / Q000166:cytology*; D033581:Stem Cell Transplantation