Distribution of anaerobic bacteria among pregnant periodontitis patients who experience preterm delivery.
The preterm delivery of low-birth-weight (PLBW) infants remains a significant public health issue and a leading cause of neonatal death and of long-term neurodevelopmental disturbances and health problems. Epidemiological and immunological studies have suggested that periodontal disease may be an independent risk factor for PLBW. The incidence of periodontal disease during pregnancy has been found to be associated with a significantly lower birth weight for gestational age after adjustment for race, parity and baby gender. The present case-control study, carried out to examine the distribution of anaerobes in pregnant women with periodontitis who experienced preterm delivery, provides microbial evidence that maternal periodontal disease and the presence of key pathogens are significant contributors to the obstetric risk of preterm delivery.
Urbán
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Institute of Clinical Microbiology, Faculty of Medicine, University of Szeged, H-6701 Szeged, P.O. Box 427, Hungary.
Radnai
Márta
M
Novák
Tibor
T
Gorzó
István
I
Pál
Attila
A
Nagy
Elisabeth
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D000293:Adolescent; D000328:Adult; D001421:Bacteria, Anaerobic / Q000145:classification / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology; D001724:Birth Weight; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015994:Incidence; D010518:Periodontitis / Q000150:complications* / Q000453:epidemiology* / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000382:microbiology; D047928:Premature Birth / Q000209:etiology*; D015995:Prevalence; D012307:Risk Factors; D016037:Single-Blind Method