The emerging link between nutrition, inflammation and atherosclerosis.
A number of dietary components modulate the inflammatory response in humans, thereby affecting cardiovascular risk. As basic research provides a better understanding of the molecular mechanisms of vascular function regulation by nutrients, clinical investigation and outcome studies demonstrate the relevance of dietary factors to the prevention and treatment of vascular disease. Benefits of dietary interventions may be attributable to weight loss or to more specialized mechanisms in which inflammation is targeted directly. Available evidence indicates that dietary intervention should be an integral part of therapeutic approaches for treating conditions such as the metabolic syndrome and, ultimately, for the prevention of cardiovascular disease.
Paoletti
Rodolfo
R
Department of Pharmacological Sciences, University of Milan, via Balzaretti 9, 20133, Milan, Italy. rodolfo.paoletti@unimi.it
Poli
Andrea
A
Cignarella
Andrea
A
D000428:Alcohol Drinking; D050197:Atherosclerosis / Q000517:prevention & control*; D031204:Caloric Restriction; D004032:Diet; D005227:Fatty Acids / Q000008:administration & dosage / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000378:metabolism; D038321:Glycemic Index; D006801:Humans; D007249:Inflammation / Q000178:diet therapy*; D024821:Metabolic Syndrome / Q000178:diet therapy; D009747:Nutritional Physiological Phenomena
D005227:Fatty Acids; D015525:Fatty Acids, Omega-3