title: Reexamination of Coccidioides spp. reserved in the Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, based on a multiple gene analysis.
abstract: The Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University is the only organization in Japan to possess a series isolates of Coccidioides spp., which are the most virulent pathogenic fungi and which are treated as biosafety level 3 microorganisms. Recently, the genus Coccidioides has been classified into two species, C. immitis and C. posadasii, based on their endemic areas and genotyping; the former species is endemic to the state of California, and the latter is endemic to other parts of North and South America. We reevaluated 19 isolates of Coccidioides immitis stored in our center using a multiple gene analysis. Five isolates were identified as C. immitis and 14 as C. posadasii. Their sequence information in GenBank will help to identify the two genospecies of Coccidioides spp.
authors.affiliation: Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Sano
authors.forename: Makoto
authors.initials: M
authors.lastname: Miyaji
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Kamei
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Mikami
authors.forename: Kazuko
authors.initials: K
authors.lastname: Nishimura
mesh_terms: D003045:Coccidioides / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D004271:DNA, Fungal / Q000235:genetics; D005785:Gene Conversion; D020459:Genes, rRNA; D005819:Genetic Markers; D014644:Genetic Variation; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D013045:Species Specificity
chemical_list: D004271:DNA, Fungal; D005819:Genetic Markers