[A case of secondary amyloidosis presenting as massive gastrointestinal bleeding].
Amyloidosis is a disorder characterized by extracellular deposition of amyloid in various tissues and organs. Gastrointestinal manifestations including gastroparesis, constipation, malabsorption, intestinal pseudo-obstruction, and bleeding are common. GI bleeding is a rare initial symptom which can be fatal in some cases. Absence of systemic symptoms and nonspecific endoscopic findings in amyloidosis may make diagnosis difficult. Therefore, amyloidosis-induced GI bleeding should be considered in patients with an obscure hemorrhage. Recently, we experienced a 65-year-old woman who presented with massive hematochezia as a manifestations of amyloidosis. Colonoscopy and SMA angiography showed massive bleeding in the small and large intestine. Colonoscopic biopsy established amyloidosis. We report this case with a review of the relevant literatures.
Kim
Hee
H
Department of Internal Medicine, Inje University College of Medicine, Paik Hospital, Busan, Korea.
Jee
Sam Ryong
SR
Lee
Sang Bong
SB
Lee
Jae Ho
JH
Park
Sung Jae
SJ
Park
Eun Taek
ET
Lee
Yeon Jae
YJ
Lee
Sang Hyuk
SH
Seol
Sang Young
SY
Chung
Jung Myung
JM
D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications* / Q000175:diagnosis