title: The diagnostic accuracy of magnetic resonance imaging in detecting cervical involvement in endometrial cancer.
abstract: OBJECTIVE
  The objective of this study was to determine the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting cervical involvement by endometrial cancer.
  
  
  METHODS
  A retrospective accuracy study of 135 consecutive women who underwent preoperative MRI and surgery for endometrial cancer at a single gynaecological cancer centre between 1st February 2003 and 30th November 2004.
  
  
  RESULTS
  For the detection of any cervical involvement by MRI, the sensitivity was 72%, specificity 93.2%, positive predictive value (PPV) 89.8%, negative predictive value (NPV) 80.2%, positive likelihood ratio (+LR) 10.7 and negative likelihood ratio (-LR) 0.3. When cervical stromal invasion was considered alone, the sensitivity was 84.4%, specificity 87.4%, PPV 67.5%, NPV 94.7%, +LR 6.7 and -LR 0.18.
  
  
  CONCLUSIONS
  We believe that MRI is able to accurately predict cervical involvement in endometrial cancer and allows a decision to be made on the type of hysterectomy to be offered.
authors.affiliation: Northern Ireland Gynaecological Oncology Centre, Level 4 North, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland, UK. Hans.nagar@btinternet.com
authors.forename: Hans
authors.initials: H
authors.lastname: Nagar
authors.forename: Stephen
authors.initials: S
authors.lastname: Dobbs
authors.forename: H Raymond
authors.initials: HR
authors.lastname: McClelland
authors.forename: John
authors.initials: J
authors.lastname: Price
authors.forename: W Glenn
authors.initials: WG
authors.lastname: McCluggage
authors.forename: Arthur
authors.initials: A
authors.lastname: Grey
mesh_terms: D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000592:standards*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery