Plasma-binding globulins and acute stress response.
Within studies of acute stress physiology an increase in glucocorticoid secretion is thought to be the primary mediator of tissue response to stress. Corticosteroid-binding globulin may regulate tissue availability of steroids, but has not been considered a dynamic component of the acute stress response. Here, we examined CBG level over the common 60-minute time frame in an acute capture and handling protocol to investigate whether CBG capacity is dynamic or static over short stressors. Using a comparative approach, we measured CBG response to capture and handling stress in nine species of birds, representing five orders and nine families. CBG capacity significantly declined within 30 - 60 minutes of capture in five of the nine species examined. This decline may serve to significantly increase the level of corticosterone reaching tissues during acute stress.
Breuner
C W
CW
Integrative Biology, University of Texas at Austin, USA. creagh@montana.edu
Lynn
S E
SE
Julian
G E
GE
Cornelius
J M
JM
Heidinger
B J
BJ
Love
O P
OP
Sprague
R S
RS
Wada
H
H
Whitman
B A
BA
D000210:Acute-Phase Reaction / Q000097:blood*; D000818:Animals; D001717:Birds / Q000097:blood* / Q000502:physiology; D001824:Body Constitution; D046091:Charadriiformes / Q000097:blood; D003345:Corticosterone / Q000097:blood; D046093:Falconiformes / Q000097:blood; D005260:Female; D046369:Finches / Q000097:blood; D046094:Galliformes / Q000097:blood; D006234:Handling, Psychological; D008297:Male; D046109:Passeriformes / Q000097:blood; D010802:Phylogeny; D013312:Stress, Physiological; D013997:Time Factors; D014156:Transcortin / Q000378:metabolism*
D014156:Transcortin; D003345:Corticosterone