Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp.
The incidence of human Campylobacter infections is increasing worldwide, as well as the proportion of isolates resistant to fluoroquinolones and/or macrolides, the drugs of choice to treat campylobacteriosis. In this review, we report recent developments in the understanding of the resistance mechanisms to fluoroquinolones and macrolides. In addition, we will discuss the recent findings on multidrug resistance in Campylobacter spp.
Payot
Sophie
S
Institut National de la Recherche Agronomique, UR086 BioAgresseurs, Santé, Environnement, Nouzilly, France. payot@tours.inra.fr
Bolla
Jean-Michel
JM
Corcoran
Deborah
D
Fanning
Séamus
S
Mégraud
Francis
F
Zhang
Qijing
Q
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects* / Q000235:genetics; D002169:Campylobacter Infections / Q000382:microbiology; D024881:Drug Resistance, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D024841:Fluoroquinolones / Q000494:pharmacology*; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D018942:Macrolides