[Vaccine for prevention of type 1 diabetes mellitus].
Diabetes mellitus type 1, known as insulin dependent diabetes mellitus (IDDM), results from a chronic autoimmune destruction of the insulin secreting pancreatic beta cells. This autoimmune process is marked by circulating auto antibodies to beta cell antigens. GAD 65 (Glutamic Acid Decarboxylase) auto antibodies are present in 70-80% of newly diagnosed patients with type 1 diabetes, and it can be detected many years before clinical onset of the disease. New knowledge in the imunopathogenesis have given expectation that imunotherapy will become routine manner for cure of diabetes mellitus type 1.
Surković
Ismana
I
Klinika za Endokrinologiju, Diabetes I Bolesti Metabolizma, Klinika Za Anesteziju I Reanimaciju, Klinicki Centar Univerziteta U Sarajevu.
Suljević
Ismet
I
Ascić-Buturović
Belma
B
Heljić
Bećir
B
D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000276:immunology / Q000517:prevention & control*; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology / Q000517:prevention & control*; D005968:Glutamate Decarboxylase / Q000276:immunology*; D006801:Humans; D050417:Insulin-Secreting Cells / Q000276:immunology; D014612:Vaccines
D001323:Autoantibodies; D014612:Vaccines; D005968:Glutamate Decarboxylase