Wound healing potential of Tragia involucrata extract in rats.
The methanol extract of the roots of Tragia involucrata topically tested at doses of 100 and 200 mg/kg exerted significant wound healing effect in Staphylococcus aureus-induced excision wound in rats.
Perumal Samy
R
R
Venom and Toxin Research Programme, Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Gopalakrishnakone
P
P
Sarumathi
M
M
Ignacimuthu
S
S
D000279:Administration, Cutaneous; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D019665:Euphorbiaceae; D005260:Female; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D051381:Rats; D017208:Rats, Wistar; D013207:Staphylococcal Skin Infections / Q000188:drug therapy* / Q000473:pathology; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000188:drug therapy* / Q000473:pathology
D000891:Anti-Infective Agents, Local; D010936:Plant Extracts