title: Postmortem diagnosis of Factor V Leiden from paraffin wax embedded tissue.
abstract: Activated protein C resistance resulting from Factor V Leiden is an important inherited thrombophilia disorder which is found in 3.5% of people in the UK. The genetic defect can be detected using the PCR and the diagnosis can be made postmortem from paraffin wax embedded tissue. The presence of Factor V Leiden should be sought in all cases of unexplained sudden death resulting from venous thromboembolism.
authors.affiliation: Molecular Haematology Unit, Department of Haematology, Bristol Royal Infirmary, Bristol BS2 8HW.
authors.forename: J S
authors.initials: JS
authors.lastname: Webb
authors.forename: G R
authors.initials: GR
authors.lastname: Standen
authors.forename: C M
authors.initials: CM
authors.lastname: Collins
authors.forename: C P
authors.initials: CP
authors.lastname: Case