title: Induction of sister chromatid exchanges in traffic policemen exposed to vehicular exhaust.
abstract: In urban areas there is an explosive growth of population and the number of automobiles. The ever-increasing vehicular traffic density is posing continued threat to the ambient air quality. Traffic policemen as a group of workers are exposed occupationally to the pollutants from vehicular exhaust. Sister chromatid exchanges (SCEs) as a biomarker of the pollutant's effect, were analyzed in peripheral blood lymphocytes of 85 traffic policemen and 60 control subjects. There was a significant increase in the mean SCEs+/-S.D./cell in the exposed group (9.31+/-5.29) when compared to the controls (4.18+/-1.85). Thus the present study concludes that vehicular exhaust might induce cytogenetic damage in traffic police. Further, the more pronounced frequency of SCEs observed in the smoking traffic policemen than in the non-smoking group suggests the joint effect of smoking and vehicular exhaust.
authors.affiliation: Department of Environmental Toxicology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, Andhra Pradesh, India. sreedevi_vreey@yahoo.co.in
authors.forename: Varre
authors.initials: V
authors.lastname: Sreedevi
authors.forename: Mundluru
authors.initials: M
authors.lastname: Hemaprasad
authors.forename: Gundimeda
authors.initials: G
authors.lastname: Sandhyadevi
authors.forename: Penagaluru Pardhanandana
authors.initials: PP
authors.lastname: Reddy
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D008875:Middle Aged; D016495:Police; D012044:Regression Analysis; D012854:Sister Chromatid Exchange / Q000187:drug effects* / Q000235:genetics*; D001335:Vehicle Emissions / Q000009:adverse effects*
chemical_list: D001335:Vehicle Emissions