title: [Effect of preliminary irradiation on DNA-ase activity and DNA fragmentation degree in the nuclei of Guerin's carcinoma cells].
abstract: The effect of preliminary irradiation on DNA-ase activity and DNA fragmentation degree in the nuclei of Guerin's carcinoma was evaluated. It was found that effective growth of malignant cells involved higher concentrations of acid DNA-ase matched by decreased levels of alkaline one which in turn lowered the rates of DNA fragmentation. Low-dose preliminary irradiation stimulated relevant processes.
authors.forename: M M
authors.initials: MM
authors.lastname: Marchenko
authors.forename: G P
authors.initials: GP
authors.lastname: Kopyl'chuk
authors.forename: I A
authors.initials: IA
authors.lastname: Shmarakov
mesh_terms: D000818:Animals; D002277:Carcinoma / Q000201:enzymology / Q000235:genetics / Q000532:radiotherapy*; D053938:DNA Fragmentation / Q000528:radiation effects*; D003851:Deoxyribonucleases / Q000378:metabolism* / Q000528:radiation effects*; D005260:Female; D009374:Neoplasms, Experimental / Q000201:enzymology / Q000235:genetics / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D051381:Rats; D013997:Time Factors
chemical_list: D003851:Deoxyribonucleases