title: Very late thrombosis after sirolimus-eluting stent implantation.
abstract: Drug-eluting stents are widely used to prevent restenosis after coronary angioplasty. We here report a case of stent thrombosis within a sirolimus-eluting stent occurring two years after stent implantation, while the patient was on chronic aspirin therapy. The patient presented with acute ST-elevation myocardial infarction and pulmonary oedema; stent thrombosis was successfully treated with coronary angioplasty and deployment of a new coronary stent. This case suggests that long-term follow-up is needed in clinical studies on drug-eluting stents.
authors.affiliation: Department of Cardiology, San Filippo Neri Hospital, Rome, Italy. vpasceri@hotmail.com
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Pasceri
authors.forename: Francesco
authors.initials: F
authors.lastname: Pelliccia
authors.forename: Cinzia
authors.initials: C
authors.lastname: Cianfrocca
authors.forename: Christian
authors.initials: C
authors.lastname: Pristipino
authors.forename: Massimo
authors.initials: M
authors.lastname: Santini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Richichi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000150:complications / Q000517:prevention & control*; D016503:Drug Delivery Systems; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology; D011654:Pulmonary Edema / Q000209:etiology; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy
chemical_list: D020123:Sirolimus