[Comparative effectiveness of 0.1% metilprednisolone aceponate and 0.05% betamethasone dipropionate among children with nonretractable prepuce].
OBJECTIVE
To compare clinical improvement between treatment with metilprednisolone aceponate vs. betamethasone dipropionate among children with nonretractable prepuce.


METHODS
Between August 2001 and November 2002, we carried out a double blind and controlled clinical trial in 34 children with a diagnosis of nonretracable prepuce. Children were randomly assigned to one of the following groups and topical treatment was administered: Group A; metilprednisolone aceponate 0. I 1% and Group B; betamethasone dipropionate 0.05%.


RESULTS
Improvement was noted in 88.2% of our sample studied; (n= 15) children from group A and 76.4% (n= 13) childrenfrom group B; however, we did not observe a significant difference when comparing percentages between the two groups (chi2 = 0.2; p = 0.6).


CONCLUSIONS
The percentage of clinical improvement was similar between the two groups of topical steroid treatment administered.
Ceballos-González
Sergio
S
Servicio de Urología, Hospital General de Zona y Medicina Familiar No. 1, IMSS, Colima, Colima, México.
Torres-Cantero
César
C
Trujillo-Hernández
Benjamín
B
Muñiz
Jesús
J
Huerta
Miguel
M
Trujillo
Xochitl
X
Vásquez
Clemente
C
D000293:Adolescent; D001623:Betamethasone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D010409:Penile Diseases / Q000188:drug therapy*; D012074:Remission Induction
D005938:Glucocorticoids; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; C078007:methylprednisolone aceponate; D008775:Methylprednisolone