title: Surgical perspectives in gastrointestinal disease: a study of quality of life outcomes in esophageal, pancreatic, colon, and rectal cancers.
abstract: Outcomes assessment in surgery traditionally has included data regarding peri-operative mortality and morbidity, as well as long-term survival and recurrence in surgical oncology. However, quality of life (QOL) is another important patient-related outcome measure. QOL data can be used to tailor treatment and improve clinical outcomes by detecting physical or psychological problems in patients that otherwise might be overlooked, but which have profound implications for the effective delivery of care. We review several well-validated QOL instruments developed specifically for use in patients with gastrointestinal malignancies, including esophageal, pancreatic and colorectal cancers, and conclude that QOL assessment routinely should be included in clinical trials of novel treatments.
authors.affiliation: Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA.
authors.forename: Kate-V
authors.initials: KV
authors.lastname: Viola
authors.forename: Charlotte
authors.initials: C
authors.lastname: Ariyan
authors.forename: Julie-Ann
authors.initials: JA
authors.lastname: Sosa
mesh_terms: D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000150:complications / Q000523:psychology / Q000601:surgery*; D023381:Endpoint Determination; D004938:Esophageal Neoplasms / Q000150:complications / Q000523:psychology / Q000601:surgery*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000150:complications / Q000523:psychology / Q000601:surgery*; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000150:complications / Q000523:psychology / Q000601:surgery*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome