title: Pediatric inflammatory bowel disease.
abstract: Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, radiology studies, and endoscopic procedures are helpful in diagnosing inflammatory bowel disease and differentiating between Crohn's disease and ulcerative colitis. Once diagnosed, the goal of medical management is to induce remission of disease while minimizing the side effects of the medication. Specific attention needs to be paid to achieving normal growth in this susceptible population. Surgical management is usually indicated for failure of medical management, complication, or malignancy. Algorithms for diagnostic evaluation and treatment of pediatric inflammatory bowel disease are presented. The specific psychosocial issues facing these patients are also discussed in this review as are the future goals of research in the complex problem of pediatric inflammatory bowel disease.
authors.affiliation: Department of Surgery, Yale University School of Medicine, Division of Pediatric Surgery, 330 Cedar Street, Rm. 132 FMB, North Haven, CT 06520, USA.
authors.forename: Karen-A
authors.initials: KA
authors.lastname: Diefenbach
authors.forename: Christopher-K
authors.initials: CK
authors.lastname: Breuer
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000465:Algorithms; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000473:pathology; D003424:Crohn Disease / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D013505:Digestive System Surgical Procedures; D018450:Disease Progression; D006801:Humans; D007223:Infant; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology / Q000628:therapy*; D011379:Prognosis
chemical_list: D000893:Anti-Inflammatory Agents