title: Primary combined squamous and small cell carcinoma of the larynx: Report of two cases and discussion of treatment modalities.
abstract: Combined small cell carcinoma (SMCC) of the larynx consists of SMCC admixed with a component of squamous cell carcinoma or adenocarcinoma. These tumors are very rare and, to date, only a few cases have been fully described. This points out the lack of information available about the correct management of these patients. Here, we describe two additional cases of combined SMCC of the larynx that illustrate the difficulties that we can encounter to diagnose correctly these patients and, by consequence, to treat them adequately.
authors.affiliation: Unité d'Oncologie Médicale, Clinique de Cancérologie Cervico-Maxillo-Faciale, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10, Av. Hippocrate, 1200, Brussels, Belgium.
authors.forename: Annelore
authors.initials: A
authors.lastname: Barbeaux
authors.forename: Lionel
authors.initials: L
authors.lastname: Duck
authors.forename: Birgit
authors.initials: B
authors.lastname: Weynand
authors.forename: Gauthier
authors.initials: G
authors.lastname: Desuter
authors.forename: Marc
authors.initials: M
authors.lastname: Hamoir
authors.forename: Vincent
authors.initials: V
authors.lastname: Gregoire
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Baurain
authors.forename: Jean-Pascal
authors.initials: JP
authors.lastname: Machiels
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome