title: Reconstructive surgery for the management of genitourinary tuberculosis: a single center experience.
abstract: OBJECTIVE
  We evaluated the role of surgery for genitourinary tuberculosis with special emphasis on reconstructive procedures.
  
  
  METHODS
  Case records of 241 patients with genitourinary tuberculosis who underwent surgery at our center during a period of 17 years were reviewed. Clinical features, organ involvement, investigations, treatment and outcome of therapy were studied.
  
  
  RESULTS
  There were 129 males and 112 females with a mean age of 34.6 years. The most common presentation was irritative voiding symptoms. Azotemia was seen in 54 (22.4%) cases. The most commonly involved organ was the kidney in 130 (53.94%) cases. Preoperative bacteriologic diagnosis was confirmed in 70 (29%) cases. All patients received antitubercular drug therapy for 9 months. A total of 248 procedures, including 33 endoscopic, 87 ablative and 128 reconstructive, were performed with some patients requiring more than 1 procedure. Early complications, which mainly involved the bowel, were seen in 19 (7.88%) cases. Bacteriologic cure was achieved in all culture positive cases. Renal functional parameters stabilized or improved in 44 of 54 patients (81.5%) in whom they were deranged at presentation.
  
  
  CONCLUSIONS
  Genitourinary tuberculosis is common in developing countries. Diagnosis is often delayed because of late presentation and many patients present with cicatrization sequelae. A combination of antitubercular drug therapy and judicious surgery achieves satisfactory results in the majority of cases. With improved antitubercular drug therapy and experience with the use of bowel segments in the urinary tract, more reconstructive procedures are being performed with satisfactory outcomes. In patients who undergo reconstructive procedures, a rigorous and prolonged followup is necessary.
authors.affiliation: Department of Urology, All India Institute of Medical Sciences, New Delhi, India. narmadagupta@hotmail.com
authors.forename: N P
authors.initials: NP
authors.lastname: Gupta
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kumar
authors.forename: O P
authors.initials: OP
authors.lastname: Mundada
authors.forename: Monish
authors.initials: M
authors.lastname: Aron
authors.forename: A K
authors.initials: AK
authors.lastname: Hemal
authors.forename: P N
authors.initials: PN
authors.lastname: Dogra
authors.forename: Amlesh
authors.initials: A
authors.lastname: Seth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures; D014401:Tuberculosis, Urogenital / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods