title: Breast carcinoma with metastasis to the gallbladder: an unusual case report with a short review of literature.
abstract: Gallbladder metastases are very rare and usually arise from malignant melanoma, renal cell carcinoma and cervical carcinoma. Breast carcinoma metastatic to the gallbladder is extremely rare and only 4 cases have been reported in the English literature. We hereby report a 54-year-old lady who was diagnosed as having breast carcinoma and underwent modified radical mastectomy. One month after the operation, she developed acute abdominal pain and underwent cholecystectomy after clinical investigation. Histopathological examination revealed metastasis to the gallbladder. Being considered a patient with metastatic breast carcinoma she was subjected to taxane and anthracycline-based palliative chemotherapy. Later she had CNS involvement and died of the progressive disease soon after few months.
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector- 5, Delhi-110085, India. dcdoval@yahoo.com
authors.forename: Dinesh C
authors.initials: DC
authors.lastname: Doval
authors.forename: Komal
authors.initials: K
authors.lastname: Bhatia
authors.forename: Keechelat
authors.initials: K
authors.lastname: Pavithran
authors.forename: Jai Bhagwan
authors.initials: JB
authors.lastname: Sharma
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Vaid
authors.forename: Digant
authors.initials: D
authors.lastname: Hazarika
mesh_terms: D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018275:Carcinoma, Lobular / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D002763:Cholecystectomy / Q000379:methods; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005706:Gallbladder Neoplasms / Q000556:secondary* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D015411:Mastectomy, Modified Radical / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology*; D035583:Rare Diseases; D018570:Risk Assessment