Magnetic field correlation imaging.
A magnetic resonance imaging (MRI) method is presented for estimating the magnetic field correlation (MFC) associated with magnetic field inhomogeneities (MFIs) within biological tissues. The method utilizes asymmetric spin echoes and is based on a detailed theory for the effect of MFIs on nuclear magnetic resonance (NMR) signal decay. The validity of the method is supported with results from phantom experiments at 1.5 and 3 T, and human brain images obtained at 3 T are shown to demonstrate the method's feasibility. The preliminary results suggest that MFC imaging may be useful for the quantitative assessment of iron within the brain.
Jensen
Jens H
JH
Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, NY 10016, USA. jens.jensen@med.nyu.edu
Chandra
Ramesh
R
Ramani
Anita
A
Lu
Hanzhang
H
Johnson
Glyn
G
Lee
Sang-Pil
SP
Kaczynski
Kyle
K
Helpern
Joseph A
JA
D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007501:Iron / Q000378:metabolism*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008280:Magnetics; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic
D007501:Iron