Efficient C-C double-bond formation reaction via a new synthetic strategy: a self-sorting tandem reaction.
[reaction: see text] A novel and efficient carbon-carbon double-bond formation reaction via coupling of aryl or heteroaryl methyl ketones has been developed. A dimethyl sulfoxide-iodine-CuO system was proven to be efficient for this reaction and afforded the expected products in good yields. A new synthetic strategy, a self-sorting tandem reaction, was involved in this type of reaction and was presented for the first time.
Yin
Guodong
G
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, Central China Normal University, Wuhan, PRC.
Zhou
Baohan
B
Meng
Xianggao
X
Wu
Anxin
A
Pan
Yuanjiang
Y