Comparative gene marker selection suite.
BACKGROUND
An important step in analyzing expression profiles from microarray data is to identify genes that can discriminate between distinct classes of samples. Many statistical approaches for assigning significance values to genes have been developed. The Comparative Marker Selection suite consists of three modules that allow users to apply and compare different methods of computing significance for each marker gene, a viewer to assess the results, and a tool to create derivative datasets and marker lists based on user-defined significance criteria.


BACKGROUND
The Comparative Marker Selection application suite is freely available as a GenePattern module. The GenePattern analysis environment is freely available at http://www.broad.mit.edu/genepattern.
Gould
Joshua
J
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. jgould@broad.mit.edu
Getz
Gad
G
Monti
Stefano
S
Reich
Michael
M
Mesirov
Jill P
JP
D000465:Algorithms; D003198:Computer Simulation; D020869:Gene Expression Profiling / Q000379:methods*; D005819:Genetic Markers / Q000235:genetics*; D016247:Information Storage and Retrieval / Q000379:methods*; D008957:Models, Genetic; D015233:Models, Statistical; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D014584:User-Computer Interface
D005819:Genetic Markers