Intact pks15/1 in non-W-Beijing Mycobacterium tuberculosis isolates.
To determine whether intact pks15/1 is unique to the W-Beijing family, we investigated 147 Mycobacterium tuberculosis strains with different IS6110 genotypes. Intact pks15/1 was found in 87.8% of cerebrospinal fluid and 84.9% of sputum isolates. It was found not only in W-Beijing strains (approximate, equals 97%) but also in other genotypes (38.5%-100%).
Chaiprasert
Angkana
A
Department of Microbiology, Faculty of Medicine-Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. siacp@mahidol.ac.th
Yorsangsukkamol
Jutaporn
J
Prammananan
Therdsak
T
Palittapongarnpim
Prasit
P
Leechawengwong
Manoon
M
Dhiraputra
Chertsak
C
D001483:Base Sequence; D002555:Cerebrospinal Fluid / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis*; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012150:Polymorphism, Restriction Fragment Length; D016415:Sequence Alignment; D013183:Sputum / Q000382:microbiology
D004269:DNA, Bacterial