title: [The research of the adsorption and desorption behaveior of macroporous resin for glycyrrhizic acid].
abstract: OBJECTIVE
  To investigate the performance of static and dynamic adsorption and desorption of the three macroporous resins of AB-8, D-101 and H-103.
  
  
  METHODS
  Compare the adsorption and desorption of the three macroporous resins for glycyrrhizic acid by determining the static adsorption, static desorption, dynamic adsorption and dynamic desorption through detecting the glycyrrhizic acid content by HPLC method.
  
  
  RESULTS
  The saturation of AB-8 is 0.75 g (crude drug)/mL (macroporous resins), the best elution reagent is 50% EtoH and it's eluation ration is 68.81% . The saturation of D-101 is 0.75 g (crude drug)/mL (macroporous resins), the best elution reagent is 60%EtoH and it's eluation ration is 64.67%. The saturation of H-103 is 0.5 g (crude drug)/mL (macroporous resins), the best elution reagent is 50%E-toH and it's elution ration is 51.18%.
  
  
  CONCLUSIONS
  AB-8 and D-101 are the superior absorbents for glycyrrhizic acid.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. wylw915@126.com
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Yue-Sheng
authors.initials: YS
authors.lastname: Wang
authors.forename: Han
authors.initials: H
authors.lastname: Yan
mesh_terms: D000327:Adsorption; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D029882:Glycyrrhiza uralensis / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012117:Resins, Synthetic
chemical_list: D012117:Resins, Synthetic; D019695:Glycyrrhizic Acid