One-pot preparation of arylalkynes by a tandem catalytic iodination of arenes and palladium-catalyzed coupling of iodoarenes with terminal alkynes.
Iodination of activated arenes by air-oxidation is carried out in the presence of catalytic bismuth salts at room temperature. Subsequently, the formed iodoarenes react with terminal alkynes to give arylalkynes under a selected palladium-catalyzed coupling condition in the same pot.
Wan
Shun
S
Department of Chemistry, Shanghai Jiao Tong University, Shanghai, China, 200240.
Wang
Sunewang R
SR
Lu
Wenjun
W
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D000480:Alkynes; D010165:Palladium; D007455:Iodine