title: Anti-inflammatory and immunosuppressive drugs and reproduction.
abstract: Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.
authors.affiliation: Department of Rheumatology and Clinical Immunology/Allergology, University Hospital of Bern, Switzerland. monika.oestensen@insel.ch
authors.forename: Monika
authors.initials: M
authors.lastname: Østensen
authors.forename: Munther
authors.initials: M
authors.lastname: Khamashta
authors.forename: Michael
authors.initials: M
authors.lastname: Lockshin
authors.forename: Ann
authors.initials: A
authors.lastname: Parke
authors.forename: Antonio
authors.initials: A
authors.lastname: Brucato
authors.forename: Howard
authors.initials: H
authors.lastname: Carp
authors.forename: Andrea
authors.initials: A
authors.lastname: Doria
authors.forename: Raj
authors.initials: R
authors.lastname: Rai
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Meroni
authors.forename: Irene
authors.initials: I
authors.lastname: Cetin
authors.forename: Ronald
authors.initials: R
authors.lastname: Derksen
authors.forename: Ware
authors.initials: W
authors.lastname: Branch
authors.forename: Mario
authors.initials: M
authors.lastname: Motta
authors.forename: Caroline
authors.initials: C
authors.lastname: Gordon
authors.forename: Guillermo
authors.initials: G
authors.lastname: Ruiz-Irastorza
authors.forename: Arsenio
authors.initials: A
authors.lastname: Spinillo
authors.forename: Deborah
authors.initials: D
authors.lastname: Friedman
authors.forename: Rolando
authors.initials: R
authors.lastname: Cimaz
authors.forename: Andrew
authors.initials: A
authors.lastname: Czeizel
authors.forename: Jean Charles
authors.initials: JC
authors.lastname: Piette
authors.forename: Ricard
authors.initials: R
authors.lastname: Cervera
authors.forename: Roger A
authors.initials: RA
authors.lastname: Levy
authors.forename: Maurizio
authors.initials: M
authors.lastname: Clementi
authors.forename: Sara
authors.initials: S
authors.lastname: De Carolis
authors.forename: Michelle
authors.initials: M
authors.lastname: Petri
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Shoenfeld
authors.forename: David
authors.initials: D
authors.lastname: Faden
authors.forename: Guido
authors.initials: G
authors.lastname: Valesini
authors.forename: Angela
authors.initials: A
authors.lastname: Tincani
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D005298:Fertility / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012098:Reproduction / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents