Inhibition of mast cell degranulation-induced drop of blood pressure with clemastine, cromolyn and compound 48/80 pretreatment.
Peternel
L
L
Drug Discovery, Lek Pharmaceuticals d.d., 1526, Ljubljana, Slovenia, luka.peternel@sandoz.com.
Cerne
M
M
Drevensek
G
G
Stempelj
M
M
Urleb
U
U
Stanovnik
L
L
Budihna
M V
MV
D000818:Animals; D018927:Anti-Asthmatic Agents / Q000009:adverse effects / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D015550:Cell Degranulation / Q000187:drug effects*; D002974:Clemastine / Q000009:adverse effects / Q000494:pharmacology*; D004205:Cromolyn Sodium / Q000009:adverse effects / Q000494:pharmacology*; D006634:Histamine H1 Antagonists / Q000009:adverse effects / Q000494:pharmacology*; D008297:Male; D008407:Mast Cells / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D003189:p-Methoxy-N-methylphenethylamine / Q000009:adverse effects / Q000494:pharmacology*
D018927:Anti-Asthmatic Agents; D006634:Histamine H1 Antagonists; D003189:p-Methoxy-N-methylphenethylamine; D002974:Clemastine; D004205:Cromolyn Sodium