Cowpox virus transmission from rats to monkeys, the Netherlands.
We report an outbreak of cowpox virus among monkeys at a sanctuary for exotic animals. Serologic analysis and polymerase chain reaction were performed on blood and swab samples from different rodent species trapped at the sanctuary during the outbreak. Sequence comparison and serologic results showed that brown rats (Rattus norvegicus) transmitted the virus to monkeys.
Martina
Byron E E
BE
Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.
van Doornum
Gerard
G
Dorrestein
Gerry M
GM
Niesters
Hubert G M
HG
Stittelaar
Koert J
KJ
Wolters
Marno A B I
MA
van Bolhuis
Hester G H
HG
Osterhaus
Albert D M E
AD
D000818:Animals; D001483:Base Sequence; D015605:Cowpox / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D015608:Cowpox virus / Q000235:genetics / Q000302:isolation & purification*; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D004196:Disease Outbreaks / Q000662:veterinary*; D004197:Disease Reservoirs / Q000662:veterinary / Q000821:virology; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D006388:Hemagglutinins / Q000737:chemistry / Q000235:genetics; D008251:Macaca; D008969:Molecular Sequence Data; D008992:Monkey Diseases / Q000635:transmission / Q000821:virology*; D009426:Netherlands; D016133:Polymerase Chain Reaction / Q000662:veterinary; D051381:Rats; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics
C088596:A-type inclusion protein, poxvirus; D004279:DNA, Viral; D006388:Hemagglutinins; D014764:Viral Proteins