[Effect of preliminary irradiation on DNA-ase activity and DNA fragmentation degree in the nuclei of Guerin's carcinoma cells].
The effect of preliminary irradiation on DNA-ase activity and DNA fragmentation degree in the nuclei of Guerin's carcinoma was evaluated. It was found that effective growth of malignant cells involved higher concentrations of acid DNA-ase matched by decreased levels of alkaline one which in turn lowered the rates of DNA fragmentation. Low-dose preliminary irradiation stimulated relevant processes.
Marchenko
M M
MM
Kopyl'chuk
G P
GP
Shmarakov
I A
IA
D000818:Animals; D002277:Carcinoma / Q000201:enzymology / Q000235:genetics / Q000532:radiotherapy*; D053938:DNA Fragmentation / Q000528:radiation effects*; D003851:Deoxyribonucleases / Q000378:metabolism* / Q000528:radiation effects*; D005260:Female; D009374:Neoplasms, Experimental / Q000201:enzymology / Q000235:genetics / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D051381:Rats; D013997:Time Factors
D003851:Deoxyribonucleases