Episodic neurologic dysfunction with migraine and reversible imaging findings after radiation.
Reported are three adults who developed frequent episodes of a complex neurologic syndrome years after radiation therapy for a brain tumor. MRI and [(18)F]fluorodeoxyglucose PET performed during the episodes demonstrated dramatic gyral thickening with enhancement and intense hypermetabolism in symptomatic regions that resolved on follow-up studies. EEG during episodes showed only slowing. The differential diagnosis and imaging findings are reviewed.
Pruitt
A
A
Division of Neuro-oncology, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA.
Dalmau
J
J
Detre
J
J
Alavi
A
A
Rosenfeld
M R
MR
D001927:Brain Diseases / Q000175:diagnosis* / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis* / Q000209:etiology*; D049268:Positron-Emission Tomography; D011832:Radiation Injuries / Q000175:diagnosis* / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*