title: [Immunohistochemical study of heme oxygenase-1 expressed in human normal dental pulp cell and tissue].
abstract: OBJECTIVE
  To study the expression of heme oxygenase-1 (HO-1) in dental pulp tissue and to find out the relationship of distribution and function of HO-1.
  
  
  METHODS
  30 pulp tissues were obtained from clinically extracted human healthy premolars and third molars. The expression of HO-1 in dental pulp was detected by means of SABC immunohistochemical technology.
  
  
  RESULTS
  HO-1 immunoreactivity was observed in vascular endothelial cells, odontoblasts and some fibroblasts cells.
  
  
  CONCLUSIONS
  The distribution of HO-1 in normal human dental pulp suggests that HO-1 may play an important role in pulp flow regulation, dentin production and its calcifying; it also may play some roles in dental pulp cells metabolism and differentiation.
authors.affiliation: Dept. of Stomatology, Medical College of Zhejiang University, Hangzhou 310006, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Zhen-Yu
authors.initials: ZY
authors.lastname: Hu
authors.forename: Hao
authors.initials: H
authors.lastname: Fang
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Cao
mesh_terms: D002454:Cell Differentiation; D003782:Dental Pulp; D003804:Dentin; D005347:Fibroblasts; D051547:Heme Oxygenase-1; D006801:Humans; D009804:Odontoblasts
chemical_list: D051547:Heme Oxygenase-1