title: [Studies on antiviral constituents in stems and leaves of Pithecellibium clypearia].
abstract: OBJECTIVE
  To study the antiviral constituents in the stems and leaves of Pithecellibium clypearia.
  
  
  METHODS
  The constituents of P. clypearia were systematically separated with various chromatographic techniques in combination with antiviral activity monitoring. Their structures were elucidated by physical and chemical properties and spectral data.
  
  
  RESULTS
  Six compounds were isolated from P. clypearia and were identified as: tricetiflavan (5, 7, 3', 4', 5'-pentahydroxylflavan) (1), myricitrin (myricetin-3-O-alpha-L-rhamnopyranoside) (2), quercitrin (quercetin-3-O-alpha-L-rhamnopyranoside) (3), quereetin (4), methyl gallate (5) and gallic acid (6).
  
  
  CONCLUSIONS
  Compound 1 approximately 5 were obtained from this plant for the first time. Compound 4 was found to show an obvious anti-respiratory syncytial virus (RSV) activity.
authors.affiliation: Chemistry Department, Life Science and Technology Institute, Jinan University, Guangzhou, China.
authors.forename: Yao-lan
authors.initials: YL
authors.lastname: Li
authors.forename: Ke-ming
authors.initials: KM
authors.lastname: Li
authors.forename: Miao-xian
authors.initials: MX
authors.lastname: Su
authors.forename: Kan-tong
authors.initials: KT
authors.lastname: Leung
authors.forename: Yu-wu
authors.initials: YW
authors.lastname: Chen
authors.forename: Yong-wen
authors.initials: YW
authors.lastname: Zhang
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012136:Respiratory Syncytial Viruses / Q000187:drug effects
chemical_list: D000998:Antiviral Agents; D005419:Flavonoids; C008577:myricitrin; C052082:methyl gallate; D005707:Gallic Acid; D011794:Quercetin