title: Retropharyngeal lymph node metastasis from olfactory neuroblastoma: A report of two cases.
abstract: Olfactory neuroblastoma is a rare, malignant neoplasm arising from the olfactory epithelium. It has an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis. The incidence of cervical lymph node metastasis in olfactory neuroblastoma is variable, and treatment modalities are controversial. Moreover, few reports have been published concerning retropharyngeal lymph node metastasis from olfactory neuroblastoma. We present two cases of olfactory neuroblastoma with retropharyngeal lymph node metastasis. In addition, we provided a review of the current literature regarding olfactory neuroblastoma and retropharyngeal lymph node metastasis from olfactory neuroblastoma.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, 120-752, South Korea.
authors.forename: Hyun Jik
authors.initials: HJ
authors.lastname: Kim
authors.forename: Jinna
authors.initials: J
authors.lastname: Kim
authors.forename: Joo-Heon
authors.initials: JH
authors.lastname: Yoon
mesh_terms: D000328:Adult; D018304:Esthesioneuroblastoma, Olfactory / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology*; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D010614:Pharynx; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed