title: Soft-tissue sarcomas and reconstruction options: twenty-two years of experience.
abstract: Soft tissue sarcomas (STS) are particularly rare malignancies that constitute less than 1% of all malignancies. In recent years, prognostic clinical factors have been defined that help to stratify patients regarding their risk for local and distant recurrence and death from disease. Tumor grade, size, depth, completeness of resection, and presentation status are among the independent prognostic factors. At present, the treatment of these tumors constitutes a wide or marginal excision, adequate primary reconstruction, and radiotherapy. Surgery has generally been recommended as the primary method of treatment for achieving local control. Modern reconstructive surgery, especially musculocutaneous, either pedicle or free flaps, has made more extensive resections possible, while providing acceptable cosmetic and functional results. This study deals with our experience in the treatment of resectable STS with selective combination of treatment modalities.
authors.affiliation: Second Department of Propedeutic Surgery of Athens University, Laiko General Hospital of Athens, Athens, Greece.
authors.forename: Othon
authors.initials: O
authors.lastname: Papadopoulos
authors.forename: Petros
authors.initials: P
authors.lastname: Konofaos
authors.forename: Chrisostomos
authors.initials: C
authors.lastname: Chrisostomidis
authors.forename: Elina
authors.initials: E
authors.lastname: Papadimitraki
authors.forename: Alexandros
authors.initials: A
authors.lastname: Stratigos
authors.forename: Alkiviadis
authors.initials: A
authors.lastname: Kostakis
mesh_terms: D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D012509:Sarcoma / Q000473:pathology / Q000601:surgery* / Q000628:therapy