title: The phosphate-starvation response of Bacillus licheniformis.
abstract: The phosphate-starvation stimulon of Bacillus licheniformis was analyzed at the transcriptional and translational level. The comparison of the transcriptome and the proteome demonstrated that this specific starvation response of B. licheniformis is partially similar to that of B. subtilis. However, it is also shown that B. licheniformis has evolved its own strategies to cope with this nutrient limitation. By means of the secretome analysis the phytase was identified as the most abundant protein under phosphate-starvation conditions. Data of this study indicate that, unlike in B. subtilis, phosphate starvation in B. licheniformis does not induce the SigmaB-dependent general stress response.
authors.affiliation: Institut für Pharmazie, Ernst-Moritz-Arndt Universität, Greifswald, Germany.
authors.forename: Le Thi
authors.initials: le T
authors.lastname: Hoi
authors.forename: Birgit
authors.initials: B
authors.lastname: Voigt
authors.forename: Britta
authors.initials: B
authors.lastname: Jürgen
authors.forename: Armin
authors.initials: A
authors.lastname: Ehrenreich
authors.forename: Gerhard
authors.initials: G
authors.lastname: Gottschalk
authors.forename: Stefan
authors.initials: S
authors.lastname: Evers
authors.forename: Jörg
authors.initials: J
authors.lastname: Feesche
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Maurer
authors.forename: Michael
authors.initials: M
authors.lastname: Hecker
authors.forename: Thomas
authors.initials: T
authors.lastname: Schweder
mesh_terms: D010832:6-Phytase / Q000378:metabolism; D001407:Bacillus / Q000737:chemistry* / Q000201:enzymology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D019295:Computational Biology; D003470:Culture Media / Q000737:chemistry; D015180:Electrophoresis, Gel, Two-Dimensional; D005798:Genes, Bacterial; D010446:Peptide Fragments / Q000737:chemistry; D010449:Peptide Mapping; D010710:Phosphates / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D020543:Proteome / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism; D013217:Starvation / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D010446:Peptide Fragments; D010710:Phosphates; D020543:Proteome; D012333:RNA, Messenger; D010832:6-Phytase