title: Technique of anaesthesia in pulmonary hypertension and thrombophilia in early pregnancy.
abstract: Pulmonary hypertension in pregnancy is a rare condition but is associated with a high mortality. We report the case of a 29 year old female in early pregnancy with Protein C and S deficiency with recurrent deep venous thrombosis and pulmonary embolism and subsequent secondary pulmonary hypertension. The patient was counselled and consented for termination of pregnancy with tubal sterilization. She was administered continuous spinal anaesthesia with invasive monitoring. The successful anaesthetic management of this condition is described.
authors.affiliation: Department of Anaesthesiology, University Malaya Medical Centre, Lembah Pantai, Kuala Lumpur 59100, Kuala Lumpur.
authors.forename: K H
authors.initials: KH
authors.lastname: Chuah
authors.forename: M
authors.initials: M
authors.lastname: Mansor
authors.forename: G
authors.initials: G
authors.lastname: Rajen
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
authors.forename: Y K
authors.initials: YK
authors.lastname: Chan
mesh_terms: D000032:Abortion, Therapeutic; D000328:Adult; D000775:Anesthesia, Spinal / Q000379:methods*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology; D011250:Pregnancy Complications, Hematologic; D020151:Protein C Deficiency / Q000503:physiopathology; D018455:Protein S Deficiency / Q000503:physiopathology; D011655:Pulmonary Embolism / Q000503:physiopathology*; D013246:Sterilization, Tubal; D019851:Thrombophilia / Q000503:physiopathology*; D013997:Time Factors; D020246:Venous Thrombosis / Q000503:physiopathology*