High-flux haemodialysis treatment as treatment for carbamazepine intoxication.
Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression. Traditionally, charcoal haemoperfusion is used to remove the drug. We present a case of carbamazepine intoxication, successfully treated with three hours of high-flux haemodialysis. Thus, haemodialysis using high-flux membranes is a feasible and effective therapeutic option for carbamazepine intoxication.
Koh
K H
KH
Kuching Sarawak General Hospital, Sarawak.
Tan
H H Clare
HH
D000208:Acute Disease; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000493:pharmacokinetics; D002220:Carbamazepine / Q000009:adverse effects* / Q000493:pharmacokinetics; D016903:Drug Monitoring; D064420:Drug-Related Side Effects and Adverse Reactions / Q000628:therapy; D004834:Epilepsy, Post-Traumatic / Q000188:drug therapy; D005260:Female; D006801:Humans; D006435:Renal Dialysis / Q000295:instrumentation / Q000379:methods*
D000927:Anticonvulsants; D002220:Carbamazepine