Parallel pathways of virus recognition.
Viruses trigger signaling pathways of innate immunity. In this issue, it is shown that the mitochondrial antiviral signaling protein is critical for intracellular detection signaling, but is dispensable for the activation of innate immunity via Toll-like receptors.
Tenoever
Benjamin R
BR
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Maniatis
Tom
T
D048868:Adaptor Proteins, Signal Transducing / Q000276:immunology*; D000818:Animals; D006801:Humans; D007113:Immunity, Innate; D008565:Membrane Proteins / Q000276:immunology; D024101:Mitochondrial Proteins / Q000276:immunology*; D009419:Nerve Tissue Proteins / Q000276:immunology; D011956:Receptors, Cell Surface; D015398:Signal Transduction / Q000276:immunology*; D014780:Viruses / Q000276:immunology*; D000097905:Roundabout Proteins
D048868:Adaptor Proteins, Signal Transducing; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D009419:Nerve Tissue Proteins; D011956:Receptors, Cell Surface; C118348:Robo3 protein, mouse; D000097905:Roundabout Proteins