title: Robustness of cascade pH and dissolved oxygen control in symbiotic nisin production process system of Lactococcus lactis and Kluyveromyces marxianus.
abstract: In symbiotic processes, different organisms coexist stably and interact by sharing the same metabolites and environmental conditions. The robustness of a symbiotic nisin production process system composed of the lactic acid bacterium Lactococcus lactis subsp. lactis (ATCC11454) and dairy yeast Kluyveromyces marxianus (MS1) was studied. It was found that this symbiotic process system was robust to the initial disturbance in the inoculum sizes of both microorganisms and pH.
authors.affiliation: Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Agustin K
authors.initials: AK
authors.lastname: Wardani
authors.forename: Sunao
authors.initials: S
authors.lastname: Egawa
authors.forename: Keisuke
authors.initials: K
authors.lastname: Nagahisa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shimizu
authors.forename: Suteaki
authors.initials: S
authors.lastname: Shioya
mesh_terms: D001709:Biotechnology / Q000379:methods*; D003612:Dairying / Q000379:methods; D005285:Fermentation; D006863:Hydrogen-Ion Concentration; D007716:Kluyveromyces / Q000378:metabolism*; D007773:Lactates / Q000737:chemistry; D019344:Lactic Acid / Q000378:metabolism; D013294:Lactococcus lactis / Q000378:metabolism*; D009561:Nisin / Q000096:biosynthesis*; D010100:Oxygen / Q000737:chemistry*; D013997:Time Factors
chemical_list: D007773:Lactates; D009561:Nisin; D019344:Lactic Acid; D010100:Oxygen