In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII.
Maes
Marie-Berthe
MB
Laboratory for Medical Biochemistry, Department of Pharmaceutical Sciences 3Division of Gastroenterology, Faculty of Medicine, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, Belgium.
Lambeir
Anne-Marie
AM
Van der Veken
Pieter
P
De Winter
Benedicte
B
Augustyns
Koen
K
Scharpé
Simon
S
De Meester
Ingrid
I
D000818:Animals; D003959:Diamines / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000633:toxicity; D018819:Dipeptidyl Peptidase 4 / Q000378:metabolism; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D015394:Molecular Structure; D010880:Piperidines / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics*; D011480:Protease Inhibitors / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000633:toxicity; D011817:Rabbits; D051381:Rats
D003959:Diamines; D010880:Piperidines; D011480:Protease Inhibitors; C512119:UAMC00039; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; C100151:dipeptidyl peptidase II; D018819:Dipeptidyl Peptidase 4