Listeria monocytogenes: a multifaceted model.
The opportunistic intracellular pathogen Listeria monocytogenes has become a paradigm for the study of host-pathogen interactions and bacterial adaptation to mammalian hosts. Analysis of L. monocytogenes infection has provided considerable insight into how bacteria invade cells, move intracellularly, and disseminate in tissues, as well as tools to address fundamental processes in cell biology. Moreover, the vast amount of knowledge that has been gathered through in-depth comparative genomic analyses and in vivo studies makes L. monocytogenes one of the most well-studied bacterial pathogens.
Hamon
Mélanie
M
Institut Pasteur, Unité des interactions Bactéries cellules, Paris 75015, France.
Bierne
Hélène
H
Cossart
Pascale
P
D000199:Actins / Q000378:metabolism; D000222:Adaptation, Physiological / Q000235:genetics / Q000502:physiology; D000818:Animals; D001426:Bacterial Proteins / Q000502:physiology; D004705:Endocytosis / Q000235:genetics / Q000502:physiology; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics / Q000502:physiology; D023281:Genomics; D006801:Humans; D007365:Intercellular Junctions / Q000235:genetics / Q000378:metabolism; D008089:Listeria monocytogenes / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology*; D008088:Listeriosis / Q000382:microbiology* / Q000503:physiopathology; D008565:Membrane Proteins / Q000502:physiology*; D051379:Mice; D015398:Signal Transduction / Q000502:physiology; D037521:Virulence Factors / Q000235:genetics
D000199:Actins; D001426:Bacterial Proteins; D008565:Membrane Proteins; D037521:Virulence Factors; C069761:internalin protein, Bacteria