Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver.
D-allose, one of the rare sugars produced from D-psicose, has been shown to be effective against reperfusion injury after ischemia and partial hepatectomy in cirrhotic rat liver by improving remnant liver blood flow and survival rates, and decreasing liver enzyme levels and liver tissue injury levels. These findings demand further study of the clinical implications of this sugar in view to the advancing fields of liver surgery and transplantation.
Hossain
Mohammad Akram
MA
Kagawa Industry Support Foundation, 2217-16 Hayashi, Takamatsu, Kagawa 761-0301, Japan. akramhossain@yahoo.com
Wakabayashi
Hisao
H
Izuishi
Kunihiko
K
Okano
Keiichi
K
Yachida
Shinichi
S
Tokuda
Masaaki
M
Izumori
Ken
K
Maeta
Hajime
H
D000818:Animals; D001663:Bilirubin / Q000737:chemistry; D005355:Fibrosis / Q000473:pathology*; D005632:Fructose / Q000378:metabolism; D005947:Glucose / Q000737:chemistry*; D006439:Hemodynamics; D006498:Hepatectomy; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008833:Microcirculation; D051381:Rats; D015427:Reperfusion Injury; D013997:Time Factors
C003243:psicose; D005632:Fructose; C002055:allose; D005947:Glucose; D001663:Bilirubin