[Thirteen cases of intrahepatic biliary cystadenoma and cystadenocarcinoma: a single center experience].
OBJECTIVE
Biliary cystadenoma (BCA) and biliary cystadenocarcinoma (BCACa) are rare cystic neoplasms that usually arise from the liver. We reviewed the clinicopathologic and radiologic findings of 13 cases of intrahepatic biliary cystic neoplasms.


METHODS
Seven patients with BCA and 6 patients with BCACa which were pathologically proven within past 10 years were included in this retrospective study.


RESULTS
BCA (7 of 7) was more common in female compared to BCACa (4 of 6). Mean age at diagnosis was 53.4 years (BCA) and 58.5 years (BCACa). Abdominal pain (54%) was the most common presenting symptom. Eleven patients (61.5%) exhibited normal liver function profiles and 5 patients (38%) showed elevated levels of serum CA19-9 levels (mean 894.2 U/mL, range: 78.7-2,080). Mean size of tumor was 11.7 cm (range: 5-15). Most frequent radiologic finding was a single cystic mass with septation. BCACa tended to have intracystic solid portion. The cut surface revealed a unilocular or multilocular cystic mass with mucinous contents. Complete surgical excision was done in 12 patients. After the complete resection, recurrence was observed in 1 case of BCACa.


CONCLUSIONS
The possibility of biliary cystic neoplasm should be suspected when an intrahepatic cystic lesion with multiseptation or solid portion is noted on imaging study. In addition, complete excision for definite diagnosis and treatment need to be performed.
Oh
Tae Hoon
TH
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Kim
Myung Hwan
MH
Lee
Sung Koo
SK
Seo
Dong Wan
DW
Lee
Sang Soo
SS
Kim
Eui Young
EY
Song
Ju Hyung
JH
Jung
Ji Hoon
JH
Lee
Sang Ah
SA
Lee
Sung Gyu
SG
Park
So Hyung
SH
Jang
Se Jin
SJ
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery; D001653:Bile Ducts, Intrahepatic; D003536:Cystadenocarcinoma / Q000473:pathology / Q000601:surgery; D003537:Cystadenoma / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged