Placental malaria and immunity to infant measles.
The efficiency of transplacental transfer of measles specific antibody was assessed in relation to placental malaria. Infection at delivery was associated with a 30% decrease in expected cord measles antibody titres. Uninfected women who received anti-malarial drugs during pregnancy transmitted 30% more antibody than those who received no antimalarial drugs.
Owens
S
S
MRC Laboratories, Atlantic Road, Fajara, The Gambia.
Harper
G
G
Amuasi
J
J
Offei-Larbi
G
G
Ordi
J
J
Brabin
B J
BJ
D000818:Animals; D000906:Antibodies / Q000097:blood*; D000962:Antimalarials / Q000627:therapeutic use; D005260:Female; D005869:Ghana; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D008457:Measles / Q000276:immunology*; D015999:Multivariate Analysis; D010922:Placenta Diseases / Q000188:drug therapy / Q000276:immunology*; D021041:Placental Circulation; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000276:immunology*
D000906:Antibodies; D000962:Antimalarials; D007074:Immunoglobulin G