title: Antioxidant activity of Arthritin--a polyherbal formulation.
abstract: In complete freund's adjuvant induced arthritis in male albino rats, a significant increase in serum lipid peroxidase besides increase in paw swelling and a significant decrease in superoxide dismutase, glutathione peroxidase and total reduced glutathione levels were observed. Arthritin produced a marked reversal of these enzyme levels, besides a significant reduction in paw swelling. The results suggest that, the polyherbal formulation 'Arthritin' exerts its effects by modulating lipid peroxidation and enhancing anti-oxidant and detoxifying enzyme systems.
authors.affiliation: Sri Ramachandra College of Pharmacy, Sri Ramachandra Medical College and Research Institute (Deemed University), Porur, Chennai 600 116, India.
authors.forename: D
authors.initials: D
authors.lastname: Chamundeeswari
authors.forename: V
authors.initials: V
authors.lastname: Vaijayanthi
authors.forename: S
authors.initials: S
authors.lastname: Umamaheswari
authors.forename: C
authors.initials: C
authors.lastname: Gandhimathi
authors.forename: S L Rajasekar
authors.initials: SL
authors.lastname: Karna
authors.forename: E
authors.initials: E
authors.lastname: Meignanam
authors.forename: J
authors.initials: J
authors.lastname: Vasantha
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D001169:Arthritis, Experimental / Q000188:drug therapy*; D029001:Herbal Medicine; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; C511390:Arthritin; D010936:Plant Extracts