Metoclopramide for migraine-associated hiccup.
Persistent hiccup can be a distressing disorder. I present a case of migraine-attack-associated sustained hiccup. Metoclopramide can swiftly control both hiccup and migraine headache. Vasopressin release probably underlies migraine-aborting action of metoclopramide while restoration of oesophageal smooth muscle function involves competitive dopaminergic antagonism and a prominent cholinergic agonist activity. Episodic prolonged hiccup associated with nausea is an unusual presenting feature of migraine.
Gupta
V K
VK
Dubai Police Medical Services, Dubai, United Arab Emirates. dr_vkgupta@yahoo.com
D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use*; D018492:Dopamine Antagonists / Q000627:therapeutic use; D006606:Hiccup / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use*; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy*
D000932:Antiemetics; D018492:Dopamine Antagonists; D008787:Metoclopramide