A new artificial urinary sphincter with conditional occlusion for stress urinary incontinence: preliminary clinical results.
OBJECTIVE
To perform a preliminary clinical investigation to determine the safety and efficacy of a novel artificial urinary sphincter (AUS) with conditional occlusion for the treatment of stress urinary incontinence.


METHODS
Male patients with urodynamically proven stress urinary incontinence after a prostatectomy were implanted with the novel AUS. They were followed up over a period of 12 months and the device tested for efficacy by using objective measurements of urinary leakage and continence. We derived a new measure for continence called the Continence Index.


RESULTS
We have demonstrated that the patients receiving the new AUS showed a reduction of greater than 10-fold in mean daily leakage volume from 770.6 ml to 55.1 ml. There was an overall improvement in the Continence Index from 54% to 97%.


CONCLUSIONS
The new AUS with conditional occlusion provides good continence rates and enables adjustment of regulating pressure in situ.
Knight
Sarah L
SL
Institute of Urology, Royal Free & University College Medical School, London, UK. s.l.knight@ucl.ac.uk
Susser
Judith
J
Greenwell
Tamsin
T
Mundy
Anthony R
AR
Craggs
Michael D
MD
D000368:Aged; D003558:Cystoscopy; D006801:Humans; D020007:Implants, Experimental / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D010865:Pilot Projects; D019736:Prostheses and Implants / Q000009:adverse effects; D014521:Urethra / Q000502:physiology; D014550:Urinary Incontinence, Stress / Q000517:prevention & control* / Q000601:surgery* / Q000628:therapy*; D016741:Urinary Sphincter, Artificial / Q000009:adverse effects; D014554:Urination / Q000502:physiology; D014563:Urodynamics