title: Demyelinating polyneuropathy in Leber hereditary optic neuropathy.
abstract: We report a patient with Leber hereditary optic neuropathy (G11778A mtDNA) and a severe demyelinating neuropathy, for which no other cause except his mitochondrial disorder could be found. The involvement of the peripheral nervous system of patients with LHON, in particular with a 11778 mtDNA, is discussed.
authors.affiliation: Department of Neurology and Neurophysiology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. gilhuis@rdgg.nl
authors.forename: H J
authors.initials: HJ
authors.lastname: Gilhuis
authors.forename: H J
authors.initials: HJ
authors.lastname: Schelhaas
authors.forename: J R M
authors.initials: JR
authors.lastname: Cruysberg
authors.forename: M J
authors.initials: MJ
authors.lastname: Zwarts
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics; D003711:Demyelinating Diseases / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D029242:Optic Atrophy, Hereditary, Leber / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D011115:Polyneuropathies / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000473:pathology
chemical_list: D004272:DNA, Mitochondrial