title: A critical analysis of nonsurgical treatment of Peyronie's disease.
abstract: OBJECTIVE
  Because the efficacy of nonsurgical therapy of Peyronie's disease is controversial, this review analyses the current status of conservative therapy of Peyronie's disease.
  
  
  METHODS
  A systematic survey on results of studies published as original papers in peer-reviewed journals is provided.
  
  
  RESULTS
  Oral drug therapies include potassium para-aminobenzoate (Potaba), vitamin E, colchicine, tamoxifen, propoleum, acetyl-L-carnitine, and propionyl-L-carnitine. Verapamil, interferon-alpha2a and interferon-alpha2b, collagenase, cortisone, hyaluronidase, and superoxide dismutase are considered intralesional therapies that have had various degrees of success. Other treatments include local gels, iontophoresis, extracorporeal shock wave therapy, and radiation.
  
  
  CONCLUSIONS
  This review analyses the current status of the conservative therapy of Peyronie's disease, because the efficacy of the nonsurgical therapy is controversial.
authors.affiliation: Department of Urology and Pediatric Urology, University Clinic Giessen and Marburg, Justus Liebig University Giessen, Germany. ekkehard.w.hauck@chiru.med.uni-giessen.de
authors.forename: Ekkehard W
authors.initials: EW
authors.lastname: Hauck
authors.forename: Thorsten
authors.initials: T
authors.lastname: Diemer
authors.forename: Hans U
authors.initials: HU
authors.lastname: Schmelz
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Weidner
mesh_terms: D000284:Administration, Oral; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D010411:Penile Induration / Q000188:drug therapy / Q000628:therapy*