title: Periorbital edema as the initial presentation of T-cell prolymphocytic leukemia.
abstract: A 57-year-old woman presented with a history of progressive bilateral upper and lower eyelid edema. Laboratory tests revealed T-cell prolymphocytic leukemia. Despite systemic treatment, she died 2 weeks after presentation. This life-threatening disorder should be added to the differential diagnosis of eyelid edema.
authors.affiliation: Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Nusz
authors.forename: Noelene K
authors.initials: NK
authors.lastname: Pang
authors.forename: John J
authors.initials: JJ
authors.lastname: Woog
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D004487:Edema / Q000175:diagnosis / Q000209:etiology*; D005141:Eyelid Diseases / Q000175:diagnosis / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015463:Leukemia, Prolymphocytic / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D015458:Leukemia, T-Cell / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D008875:Middle Aged; D009916:Orbital Diseases / Q000175:diagnosis / Q000209:etiology*
chemical_list: D014408:Biomarkers, Tumor