title: Parent-of-origin effects on mRNA expression in Drosophila melanogaster not caused by genomic imprinting.
abstract: Parent-of-origin effects create differences in gene expression among genetically identical individuals. Using measurements of allele-specific expression, we demonstrate that previously reported parent-of-origin effects on standing mRNA levels in Drosophila melanogaster are not attributable to genomic imprinting. Offspring from reciprocal crosses exhibit differences in total expression without differences in allelic expression, indicating that other types of maternal and/or paternal effects alter expression.
authors.affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA. wittkopp@umich.edu
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Wittkopp
authors.forename: Belinda K
authors.initials: BK
authors.lastname: Haerum
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Clark
mesh_terms: D000483:Alleles; D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics* / Q000378:metabolism; D005260:Female; D005786:Gene Expression Regulation; D018392:Genomic Imprinting; D040582:Inheritance Patterns; D008297:Male; D012333:RNA, Messenger / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger