title: The fetal sex ratio and metabolic, biochemical, haematological and clinical indicators of severity of hyperemesis gravidarum.
abstract: The association between female fetal sex and hyperemesis gravidarum is well established in European and North American populations. The association between female fetuses and severity of hyperemesis remains uncertain. A retrospective study based on case notes review of 166 Asian women hospitalised for hyperemesis was performed. Female fetuses were significantly associated with hyperemesis in our population (P= 0.004, OR 1.6, 95% CI 1.2-2.2) as well as associated with severe ketonuria and high urea. When both severe ketonuria and high urea were present at initial hospital admission for hyperemesis, 83% (95% CI 66-93) of the fetuses were female.
authors.affiliation: Department of Obstetrics & Gynecology, University of Malaya, Kuala Lumpur, Malaysia. pctan@um.edu.my
authors.forename: P C
authors.initials: PC
authors.lastname: Tan
authors.forename: R
authors.initials: R
authors.lastname: Jacob
authors.forename: K F
authors.initials: KF
authors.lastname: Quek
authors.forename: S Z
authors.initials: SZ
authors.lastname: Omar
mesh_terms: D000328:Adult; D005260:Female; D005333:Fetus; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000209:etiology* / Q000652:urine; D007657:Ketone Bodies / Q000652:urine; D011247:Pregnancy; D012044:Regression Analysis; D012189:Retrospective Studies; D012737:Sex Factors; D012744:Sex Ratio; D014508:Urea / Q000097:blood
chemical_list: D007657:Ketone Bodies; D014508:Urea