title: Easy access to the family of thiazole N-oxides using HOF x CH3CN.
abstract: An efficient procedure for transferring an oxygen atom to thiazole-containing compounds, resulting in the corresponding N-oxides, was developed by using HOF x CH3CN; mild reaction conditions, high yields and easy purification are the main features of this novel route, while X-ray structural analysis reveals a hydrogen bond between the N-oxide functionality and a water molecule.
authors.affiliation: School of Chemistry, Tel-Aviv University, Tel-Aviv, Israel 69978.
authors.forename: Elizabeta
authors.initials: E
authors.lastname: Amir
authors.forename: Shlomo
authors.initials: S
authors.lastname: Rozen
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*; D014867:Water; D014961:X-Ray Diffraction
chemical_list: D000097:Acetonitriles; D010087:Oxides; D013844:Thiazoles; D014867:Water; D005461:Fluorine; D006859:Hydrogen