Psychiatric disorders in patients with psychogenic non-epileptic seizures, with and without comorbid epilepsy.
OBJECTIVE
The aim of this study is to describe similarities and differences in epidemiological, psychiatric and semiologic variables between patients with psychogenic none epileptic seizures (PNES) and comorbid epilepsy (mixed PNES), and patients with PNES without comorbid epilepsy (pure PNES).


RESULTS
Forty-three patients with PNES diagnosed by Video-EEG were included. Twenty-four had pure PNES, and ninteen mixed PNES. Female population, age, duration of PNES, psychiatric institutionalization, psychopharmacotherapy, dissociative disorders and posttraumatic stress disorder (PTSD), were significantly higher in the pure PNES patients. Suicide attempts, antiepileptic therapy, conversive, affective and personality disorders were frequent in both groups. In the analysis of seizure semiology, the total lack of responsiveness was significantly higher in the mixed PNES group.


CONCLUSIONS
Pure PNES patients showed similarities and differences in the psychiatric profile, with a greater prevalence of dissociative disorders and PTSD, factors related to psychiatric severity.
D'Alessio
Luciana
L
Epilepsy Center, Ramos Mejía Hospital, Buenos Aires, Argentina. ldalessio@intramed.net.ar
Giagante
Brenda
B
Oddo
Silvia
S
Silva W
Walter
W
Solís
Patrícia
P
Consalvo
Damián
D
Kochen
Silvia
S
D000328:Adult; D015897:Comorbidity; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000145:classification / Q000453:epidemiology*; D011602:Psychophysiologic Disorders / Q000453:epidemiology*; D012640:Seizures / Q000150:complications / Q000523:psychology*; D013406:Suicide, Attempted / Q000706:statistics & numerical data; D014741:Video Recording