title: Genital anaesthesia persisting six years after sertraline discontinuation.
abstract: Sexual side-effects, in general, are common with selective serotonin-reuptake inhibitors (SSRIs). Genital anaesthesia is a rare side-effect previously described with sertraline and fluoxetine use. With SSRI discontinuation, the sexual side-effects are expected to resolve. We report a case of a 26-year-old male who experienced genital anaesthesia during sertraline treatment and continued to be symptomatic despite medication discontinuation 6 years previously. To date, there have been no published reports of SSRI-induced sexual side-effects persisting beyond SSRI discontinuation. This case highlights the complex interplay of psychopharmacologic and psychodynamic factors that can occur in patients with sexual dysfunction.
authors.affiliation: Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.
authors.forename: James M
authors.initials: JM
authors.lastname: Bolton
authors.forename: Jitender
authors.initials: J
authors.lastname: Sareen
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Reiss
mesh_terms: D000328:Adult; D003863:Depression / Q000188:drug therapy; D006801:Humans; D006987:Hypesthesia / Q000139:chemically induced*; D008297:Male; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced*
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors