[Pachydermoperiostosis (primary hypertrophic osteoarthropathy)].
Pachydermoperiostosis or primary hypertrophic osteoarthropathy is a rare disease characterized by cutaneous and osteoarthicular involvement. We describe two patients with finger clubbing, watch crystal nails, bones thickenings, arthritis and different grades of skin affection, without other clinical manifestations. Both did not know of having relatives with the same alterations. Radiological studies of the affected areas showed periostosis. Because of normal laboratory results and chest radiography plus the absence of other underlying causes, diagnosis of primary hypertrophic osteoarthropathy was made.
Cavallasca
Javier A
JA
División Reumatología, Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires. jcavallasca@yahoo.com.ar
Malah
Veronica A
VA
Fernandez
Daniel E
DE
Carbia
Sergio G
SG
Nasswetter
Gustavo G
GG
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D011859:Radiography