Angiokeratoma corporis diffusum in a patient with no recognizable enzyme abnormalities.
BACKGROUND
Angiokeratoma corporis diffusum is a clinical variant of angiokeratoma that is typically associated with an enzyme deficiency in the metabolism of glycoprotein, most notably Fabry disease, resulting in many other systemic manifestations.


METHODS
We report a case of angiokeratoma corporis diffusum that did not have an identifiable enzyme deficiency. A review of the literature revealed few similar cases.


CONCLUSIONS
Angiokeratoma corporis diffusum without recognizable enzyme deficiencies appears to be a distinct clinical entity with a benign course.
Kelly
Brent
B
Department of Dermatology, University of Texas Medical Branch at Galveston, USA. bckelly@utmb.edu
Kelly
Erica
E
D000328:Adult; D003937:Diagnosis, Differential; D000795:Fabry Disease / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D006119:Groin; D006801:Humans; D008297:Male