title: Seroprevalence of Chagas disease in schoolchildren from two municipalities of Jequitinhonha Valley, Minas Gerais, Brazil; six years following the onset of epidemiological surveillance.
abstract: Six years after the beginning of the epidemiological surveillance of Chagas disease in Berilo and José Gonçalves de Minas, Jequitinhonha Valley, MG, Brazil, a serological inquiry was performed to observe whether the transmission of this endemy was occurring in this area. A randomized sample of 1,412 children seven to 14 years old, was screened. Six asymptomatic children were found to be positive, leading to 0.4% of prevalence. Hemoculture confirmed infection in five out of the six positive cases. Additional epidemiological investigation revealed important antecedents, such as disease reports in relatives and predisposing ecological and housing conditions. Our results demonstrated similar seroprevalence (0.4%) in schoolchildren, ranging from seven to 14 years old, and that were observed six years ago (0.2%) for children 0-9 year-old. Thus, considering the constant presence of Panstrogylus megistus in the peridomicile these findings emphasize the need of continuous improved epidemiological surveillance of Chagas disease in this region.
authors.affiliation: Instituto de Ciências Exatas e Biológicas, UFOP, Ouro Preto, MG, Brazil.
authors.forename: Jaila Dias
authors.initials: JD
authors.lastname: Borges
authors.forename: Girley Francisco Machado de
authors.initials: GF
authors.lastname: Assis
authors.forename: Lizziani Vasconcelos
authors.initials: LV
authors.lastname: Gomes
authors.forename: João Carlos Pinto
authors.initials: JC
authors.lastname: Dias
authors.forename: Ildikô Delkim Miranda
authors.initials: ID
authors.lastname: Pinto
authors.forename: Olindo Assis
authors.initials: OA
authors.lastname: Martins-Filho
authors.forename: Rosália Morais
authors.initials: RM
authors.lastname: Torres
authors.forename: Pedro Albajar
authors.initials: PA
authors.lastname: Viñas
authors.forename: Maria Terezinha
authors.initials: MT
authors.lastname: Bahia
authors.forename: George Luiz Lins
authors.initials: GL
authors.lastname: Machado-Coelho
authors.forename: Marta de
authors.initials: Md
authors.lastname: Lana
mesh_terms: D000293:Adolescent; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008297:Male; D014349:Trypanosoma cruzi / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan