Phylogenetic tree construction of butyrylcholinesterase sequences in life forms.
Butyrylcholinesterase is an enzyme with few known physiological functions. It is related to acetylcholine that was shown to be expressed in a variety of life forms. We performed a search using the human butyrylcholinesterase gene (HGNC:983;MIM:177400), and found the sequence in a broad spectrum including plants, bacteria and animals. Therefore butyrylcholinesterase appears to have evolved early in evolution, and to have been conserved.
Sridhar
G R
GR
Endocrine and Diabetes Centre, 15-12-16 Krishnanagar, Visakhapatnam 530 002, India.
Lakshmi
P V
PV
Rao
Allam Appa
AA
D000110:Acetylcholinesterase / Q000235:genetics; D000595:Amino Acid Sequence; D000818:Animals; D001419:Bacteria / Q000201:enzymology; D001483:Base Sequence; D002091:Butyrylcholinesterase / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D010944:Plants / Q000201:enzymology*
D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase