title: Loss-of-function alleles of the JIL-1 kinase are strong suppressors of position effect variegation of the wm4 allele in Drosophila.
abstract: In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the wm4 allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer Evar2-1 on PEV.
authors.affiliation: Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lerach
authors.forename: Weiguo
authors.initials: W
authors.lastname: Zhang
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Bao
authors.forename: Huai
authors.initials: H
authors.lastname: Deng
authors.forename: Jack
authors.initials: J
authors.lastname: Girton
authors.forename: Jørgen
authors.initials: J
authors.lastname: Johansen
authors.forename: Kristen M
authors.initials: KM
authors.lastname: Johansen
mesh_terms: D000483:Alleles; D000818:Animals; D004330:Drosophila; D029721:Drosophila Proteins / Q000235:genetics*; D005799:Genes, Dominant; D016153:Genes, Suppressor; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*
chemical_list: D029721:Drosophila Proteins; C507306:JIL-1 protein, Drosophila; D017346:Protein Serine-Threonine Kinases