title: FloDots: luminescent nanoparticles.
abstract: Luminescent dye-doped silica nanoparticles (FloDots) have been developed for ultrasensitive bioanalysis and diagnosis in the past several years. Those novel nanoparticles are highly luminescent and extremely photostable. In this paper, we review the preparation, characterization, bioconjugation and bioapplication of FloDots. All the results clearly demonstrated that FloDots have many advantages over currently used luminescent probes, such as traditional fluorophores and quantum dots.
authors.affiliation: Center for Research at the Bio/nano Interface, Department of Chemistry and Shands Cancer Center, University of Florida, Gainesville, FL 32611-7200, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Yao
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.forename: Yanrong
authors.initials: Y
authors.lastname: Wu
authors.forename: Josh
authors.initials: J
authors.lastname: Smith
authors.forename: Jinsheng
authors.initials: J
authors.lastname: Xu
authors.forename: Wenjun
authors.initials: W
authors.lastname: Zhao
authors.forename: Eunjung
authors.initials: E
authors.lastname: Lee
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D006801:Humans; D049449:Luminescence; D046228:Microarray Analysis; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010777:Photochemistry