title: [Vacuum-assisted stereotactic biopsy: experience of the regional cancer center of Caen].
abstract: OBJECTIVE
  To report our experience with macrobiopsy under stereotaxy.
  
  
  METHODS
  Retrospective study of 248 procedures in 236 patients for microcalcifications in 95% of cases. The macrobiopsies were performed under Mammotome for lesions graded ACR 3, ACR 4 and ACR 5 in 8.4%, 81.6% and 14.8% of cases respectively.
  
  
  RESULTS
  From a technical point of view, 91% of procedures had no technical problem. The image guided excision was complete in 68% of cases with lesions less than 1 cm in size and in 6% of cases for lesions larger than 1 cm. The rate of a misdiagnosis of ductal carcinoma in situ for patients with invasive carcinoma was 27% whereas the rate of a misdiagnosis of atypical ductal hyperplasia in patients with ductal carcinoma in situ was 25% knowing that patients with atypical ductal hyperplasia for which all microcalcifications had been fully removed by macrobiopsy and without risk factors did not undergo surgery.
  
  
  CONCLUSIONS
  Even if macrobiopsy of microcalcifications is a reliable method, its main limitation remains the risk of misdiagnosis of borderline lesions.
authors.affiliation: Centre François Baclesse, avenue du général Harris, 14076 Caen 5.
authors.forename: V
authors.initials: V
authors.lastname: Bouté
authors.forename: D
authors.initials: D
authors.lastname: Baille-Barrelle
authors.forename: Y
authors.initials: Y
authors.lastname: Denoux
authors.forename: J
authors.initials: J
authors.lastname: Marnay
authors.forename: J
authors.initials: J
authors.lastname: Lacroix
authors.forename: B
authors.initials: B
authors.lastname: Marie
authors.forename: J J
authors.initials: JJ
authors.lastname: Michels
authors.forename: H
authors.initials: H
authors.lastname: Crouet
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods*; D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D004867:Equipment Design; D005260:Female; D006801:Humans; D011859:Radiography; D012189:Retrospective Studies; D014618:Vacuum