title: Large decreases in insulin requirement occurred repeatedly in two pregnancies in a type 1 diabetic woman.
abstract: Whereas the increase in insulin requirement in late gestation is well described in diabetic pregnancy, a decrease in insulin dosage in the end of the third trimester has also been noted in clinical experience and the prevention of hypoglycaemia is important. Here we report a large decrease (over 50%) in the final few weeks of her two gestations in a woman with type 1 diabetes mellitus.
authors.affiliation: Department of Internal Medicine, Yamanaka-spa Medical Center, Ishikawa, Japan. ririoka@mail.goo.ne.jp
authors.forename: R
authors.initials: R
authors.lastname: Oka
authors.forename: T
authors.initials: T
authors.lastname: Iura
authors.forename: S
authors.initials: S
authors.lastname: Miyamoto
mesh_terms: D000293:Adolescent; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin