Antiretroviral drug resistance and routine therapy, Cameroon.
Among 128 patients routinely receiving highly active antiretroviral therapy in an HIV/AIDS outpatient clinic in Cameroon, 16.4% had drug resistance after a median of 10 months. Of these, 12.5% had resistance to nucleoside reverse transcriptase inhibitors (NRTIs), 10.2% to non-NRTIs, and 2.3% to protease inhibitors.
Laurent
Christian
C
Institut de Recherche pour le Développement (UMR 145), Montpellier, France. Christian.Laurent@mpl.ird.fr
Kouanfack
Charles
C
Vergne
Laurence
L
Tardy
Michèle
M
Zekeng
Léopold
L
Noumsi
Nathalie
N
Butel
Christelle
C
Bourgeois
Anke
A
Mpoudi-Ngolé
Eitel
E
Koulla-Shiro
Sinata
S
Peeters
Martine
M
Delaporte
Eric
E
D000328:Adult; D000595:Amino Acid Sequence; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D001483:Base Sequence; D002163:Cameroon / Q000453:epidemiology; D003430:Cross-Sectional Studies; D024882:Drug Resistance, Viral / Q000235:genetics*; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology; D015497:HIV-1 / Q000235:genetics / Q000254:growth & development*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D012703:Serotyping; D014505:Urban Population
D012367:RNA, Viral