title: Case report: the significance of genotyping for the epidemiological tracing of classical swine fever (CSF).
abstract: In Germany, eleven outbreaks of CSF in domestic pig holdings were reported in 2002. They occurred exclusively in regions where CSF virus circulated in the wild boar population. In ten cases the phylogenetic analysis revealed that the isolates from domestic pigs and wild boar had identical sequences in the 5' non-translated region (5'NTR). However, in one case a subtype was isolated which was slightly different from the virus subtype found in the wild boar population of that region. This case is decribed in detail. The epidemiological significance of different diagnostic methods is discussed, in particular the genetic typing of CSF virus isolates.
authors.affiliation: Friedrich-Loeffler-lnstitut, Insel Riems-Greifswald, Germany.
authors.forename: K R
authors.initials: KR
authors.lastname: Depner
authors.forename: G
authors.initials: G
authors.lastname: Strebelow
authors.forename: Ch
authors.initials: Ch
authors.lastname: Staubach
authors.forename: M
authors.initials: M
authors.lastname: Kramer
authors.forename: J
authors.initials: J
authors.lastname: Teuffert
authors.forename: L
authors.initials: L
authors.lastname: Bötcher
authors.forename: B
authors.initials: B
authors.lastname: Hoffmann
authors.forename: M
authors.initials: M
authors.lastname: Beer
authors.forename: I
authors.initials: I
authors.lastname: Greiser-Wilke
authors.forename: T
authors.initials: T
authors.lastname: Mettenleiter
mesh_terms: D000818:Animals; D006691:Classical Swine Fever / Q000453:epidemiology*; D006692:Classical Swine Fever Virus / Q000145:classification* / Q000235:genetics*; D004196:Disease Outbreaks / Q000662:veterinary; D005838:Genotype; D005858:Germany / Q000453:epidemiology; D017720:Molecular Epidemiology; D009500:Neutralization Tests / Q000662:veterinary; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis; D034421:Sus scrofa / Q000821:virology*; D013552:Swine
chemical_list: D012367:RNA, Viral