Colonic mucosal tears in collagenous colitis.
In general, the colonic mucosa is macroscopically normal in collagenous colitis, although minor, non-specific abnormalities may be found. Significant endoscopic abnormalities, "mucosal tears" representing longitudinal mucosal lacerations, have been reported in a few patients with collagenous colitis. We report the cases of three women with collagenous colitis and mucosal tears detected at the index colonoscopy in order to illustrate the endoscopic characteristics and review the literature. Including the present cases, a total of 12 patients with mucosal tears and collagenous colitis have been reported. In 10 patients, the mucosal lacerations involved the ascending or the transverse colon. Three of the 12 patients had a colonic perforation immediately after the colonoscopy. The colonoscopist should be aware that the risk of perforation is likely to be increased when mucosal tears are present.
Wickbom
Anna
A
Division of Gastroenterology, Department of Medicine, Orebro University Hospital, Orebro, Sweden.
Lindqvist
Magnus
M
Bohr
Johan
J
Ung
Kjell-Arne
KA
Bergman
Jan
J
Eriksson
Sune
S
Tysk
Curt
C
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D019819:Budesonide / Q000627:therapeutic use; D002908:Chronic Disease; D046729:Colitis, Collagenous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D003106:Colon / Q000293:injuries*; D003113:Colonoscopy / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D019819:Budesonide