[A case of severe intestinal tuberculosis, treated with ciprofloxacin, kanamycin and prednisolone].
A 31-year-old man was admitted to our hospital because of frequent diarrhea. Colonoscopy showed ring ulcers on the rectum and ascending colon and chest X-ray showed abnormal shadows which were diagnosed as tuberculosis by sputum PCR. He started treatment with isoniazid (INH), rifampicin (RFP), pyrazinamide (PZA) and streptomycin (SM), however, eruption and ileus were seen. Then, he was retreated with ciprofloxacin (CPFX), kanamycin sulfate (KM) and prednisolone (PSL). Subsequently, we added RFP and further added calcium para-aminosalicylate (PAS). All these treatment was effective, and he was discharged from the hospital.
Shirai
Masahiro
M
Department of Internal Medicine, NHO Tenryu National Hospital, 4201-2, Oro, Hamamatsu-shi, Shizuoka 434-8511 Japan. shiraim@smail.plala.or.jp
Hayakawa
Hiroshi
H
Nakano
Yasukatsu
Y
Nakamura
Yutaro
Y
Fujita
Kaoru
K
Suda
Takafumi
T
Chida
Kingo
K
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007612:Kanamycin / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D014385:Tuberculosis, Gastrointestinal / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D007612:Kanamycin; D002939:Ciprofloxacin; D011239:Prednisolone