MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever.
Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We describe a diagnostic system for rapid, multiplex polymerase chain reaction identification of 10 different causes of viral hemorrhagic fevers.
Palacios
Gustavo
G
Columbia University, New York, New York 10032, USA.
Briese
Thomas
T
Kapoor
Vishal
V
Jabado
Omar
O
Liu
Zhiqiang
Z
Venter
Marietjie
M
Zhai
Junhui
J
Renwick
Neil
N
Grolla
Allen
A
Geisbert
Thomas W
TW
Drosten
Christian
C
Towner
Jonathan
J
Ju
Jingyue
J
Paweska
Janusz
J
Nichol
Stuart T
ST
Swanepoel
Robert
R
Feldmann
Heinz
H
Jahrling
Peter B
PB
Lipkin
W Ian
WI
D003937:Diagnosis, Differential; D006482:Hemorrhagic Fevers, Viral / Q000175:diagnosis* / Q000821:virology*; D006801:Humans; D008970:Molecular Weight; D016133:Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D012984:Software