[Effect of estradiol on stimulated theophylline and prolactin Ca2+ exit from intracellular stores of pig oocytes].
Effect of estradiol on stimulated theophylline and prolactin Ca2+ exit from intracellular stores of pig oocytes was investigated using fluorescent dye chlortetracycline. It was shown that in the presence of estradiol neithert theophylline nor prolactin stimulated Ca2+ exit from intracellular stores of oocytes. Unlike, the common action oftheophylline and prolactin, also in the presence of estradiol, stimulated Ca2+ exit from intracellular stores. Inhibition of protein kinase C inhibits Ca2+ exit from intracellular stores in common action of theophylline and prolactin. These data suggest an obvious influence of estradiol on Ca2+ exit from intracellular stores of pig oocytes stimulated by theophylline and prolactin.
Denisenko
V Iu
VIu
Kuz'mina
T I
TI
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D009865:Oocytes / Q000187:drug effects / Q000378:metabolism*; D011388:Prolactin / Q000494:pharmacology*; D013552:Swine; D013806:Theophylline / Q000494:pharmacology*
D004958:Estradiol; D011388:Prolactin; D013806:Theophylline; D002118:Calcium