Virulence factors and resistance mechanisms of Serratia marcescens. A short review.
Serratia marcescens, a Gram-negative bacillus that belongs to the family Enterobacteriaceae, is a human opportunistic pathogen bacterium that causes many diseases, such as urinary tract infections, respiratory tract infections, bacteremia, conjunctivitis, endocarditis, meningitis and wound infections. Many plasmides that confers multi-drug resistance were discovered, such as virulence factors, like cytotoxins that damage epithelial cells. The main topic of this paper presents a review about the molecular traits evolved in the pathogenic processes mediated by Serratia and its mechanism of resistance to drugs.
Rodrigues
Ana P
AP
Faculdade de Medicina de Juazeiro do Norte, FMJ Ceará, Brazil.
Holanda
A R M
AR
Lustosa
G P
GP
Nóbrega
S M B
SM
Santana
Willma J
WJ
Souza
Luciana B S
LB
Coutinho
H D M
HD
D000890:Anti-Infective Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D017494:Proton Pumps; D016868:Serratia Infections / Q000382:microbiology; D012706:Serratia marcescens / Q000187:drug effects* / Q000378:metabolism*; D037521:Virulence Factors / Q000378:metabolism*
D000890:Anti-Infective Agents; D017494:Proton Pumps; D037521:Virulence Factors