title: Nasal dermoplasty for Japanese hereditary hemorrhagic telangiectasia.
abstract: OBJECTIVE
  While generally considered an effective treatment for moderate to severe epistaxis in hereditary hemorrhagic telangiectasia (HHT), nasal dermoplasty (ND) has not been well established in Japan. This prompted the present Japanese assessment of clinical efficacy and patient satisfaction following this procedure.
  
  
  METHODS
  Retrospective analysis of clinical records of 15 patients with HHT undergoing ND between August 1991 and May 2004 and survey of these patients as to postsurgical conditions. Main outcome measures were skin graft "take" frequency after surgery (all patients), reported patient satisfaction (eight recent patients), and reported volume and frequency of epistaxis after versus before surgery (eight recent patients).
  
  
  RESULTS
  Graft take rate was 100%. Most patients experienced reduced frequency and volume of bleeding. One patient required an additional operation, total closure of the external nares, 2 years later. Overall patients felt satisfied with ND, experiencing less nasal obstruction than expected.
  
  
  CONCLUSIONS
  ND is effective in Japanese patients with moderate and severe nasal bleeding from HHT, reducing their risk of bleeding.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan. k-ichi@jichi.ac.jp
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ichimura
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Tanaka
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Nakamura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000464:Alginates / Q000627:therapeutic use; D004564:Electrocoagulation; D004844:Epistaxis / Q000601:surgery; D005260:Female; D020723:Glucuronic Acid / Q000627:therapeutic use; D006490:Hemostatics / Q000627:therapeutic use; D006603:Hexuronic Acids / Q000627:therapeutic use; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000601:surgery*; D017060:Patient Satisfaction; D012189:Retrospective Studies; D016038:Skin Transplantation / Q000379:methods*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000601:surgery*
chemical_list: D000464:Alginates; D006490:Hemostatics; D006603:Hexuronic Acids; D020723:Glucuronic Acid