title: Fibrin sealant for Müller muscle-conjunctiva resection ptosis repair.
abstract: OBJECTIVE
  To determine the safety and efficacy of fibrin sealant for use in Müller muscle-conjunctiva resection ptosis repair.
  
  
  METHODS
  This was a retrospective review of a consecutive case series. All patients underwent Müller muscle-conjunctiva resection ptosis repair with fibrin sealant used for wound closure. Surgery was performed in a manner similar to a previously described technique, using fibrin tissue sealant rather that suture for wound closure. Postoperative symmetry was defined as MRD1 of each eyelid within 0.5 mm.
  
  
  RESULTS
  Müller muscle-conjunctiva resection ptosis repair with fibrin sealant used for wound closure was performed on 53 eyelids of 33 patients. There were 27 female patients and 6 male patients. Twenty patients underwent bilateral ptosis repair and 13 patients underwent unilateral ptosis repair. Average follow-up was 17 weeks (range, 3 to 45 weeks). Mean preoperative MRD1 was 1.22 mm (range, -1.5 to 2.5 mm) in the right upper eyelid and 1.50 mm (range, 0 to 2 mm) in the left upper eyelid. Mean postoperative MRD1 was 3.11 mm (range, 2 to 4.5 mm) in the right upper eyelid and 3.12 mm (range, 1 to 4.5 mm) in the left upper eyelid. Postoperative symmetry was found in 32 of 33 patients (97%). We found no evidence of keratopathy or other complications attributable to the fibrin sealant.
  
  
  CONCLUSIONS
  Müller muscle-conjunctiva resection ptosis repair with fibrin sealant used for wound closure may allow for predictable results with few complications and appears to be an acceptable alternative to traditional suture techniques.
authors.affiliation: The Ohio State University, Columbus, USA.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Foster
authors.forename: David E E
authors.initials: DE
authors.lastname: Holck
authors.forename: Julian D
authors.initials: JD
authors.lastname: Perry
authors.forename: Allan E
authors.initials: AE
authors.lastname: Wulc
authors.forename: John A
authors.initials: JA
authors.lastname: Burns
authors.forename: Kenneth V
authors.initials: KV
authors.lastname: Cahill
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Morgenstern
mesh_terms: D001763:Blepharoptosis / Q000601:surgery*; D003228:Conjunctiva / Q000601:surgery*; D005143:Eyelids / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000009:adverse effects / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009801:Oculomotor Muscles / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures; D012189:Retrospective Studies; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives