title: Lung injury from "liquid ecstasy": a role for coagulation activation?
abstract: We describe our second clinical observation of pulmonary injury after a "liquid ecstasy" ingestion/inhalation by a 3-year-old girl. Apart from the deep coma state, a markedly asymmetric pulmonary compromise was recorded. A transient coagulation activation was detected, possibly triggered off by the toxic effect on the lung alveolar-capillary membrane.
authors.affiliation: Pediatric Intensive Care Unit, Catholic University Medical School, Gemelli Hospital, Rome, Italy. marco.piastra@fastwebnet.it
authors.forename: Marco
authors.initials: M
authors.lastname: Piastra
authors.forename: Alessia
authors.initials: A
authors.lastname: Tempera
authors.forename: Elena
authors.initials: E
authors.lastname: Caresta
authors.forename: Antonio
authors.initials: A
authors.lastname: Chiaretti
authors.forename: Orazio
authors.initials: O
authors.lastname: Genovese
authors.forename: Giulia
authors.initials: G
authors.lastname: Zorzi
authors.forename: Silvia
authors.initials: S
authors.lastname: Pulitanò
authors.forename: Domenico
authors.initials: D
authors.lastname: Pietrini
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Polidori
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000627:therapeutic use; D000990:Antithrombin III / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy; D002675:Child, Preschool; D005260:Female; D006213:Hallucinogens / Q000506:poisoning*; D006801:Humans; D019570:Inhalation Exposure; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000506:poisoning*; D011654:Pulmonary Edema / Q000097:blood* / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D015842:Serine Proteinase Inhibitors / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D006213:Hallucinogens; D015842:Serine Proteinase Inhibitors; D000990:Antithrombin III; D018817:N-Methyl-3,4-methylenedioxyamphetamine