Novel phloroglucinol derivatives from the roots of Lysidice rhodostegia.
[structure: see text] Three novel phloroglucinol derivatives of lysidicins A-C (1-3) have been isolated from the roots of Lysidice rhodostegia and structures were elucidated by comprehensive NMR and MS spectroscopic analysis. 1 and 2 possess spirocyclic benzodihydrofuran skeleton. Their relative stereochemistries were assigned by NOE or NOESY experiment. A plausible pathway for the biosynthesis of 1-3 from 4 and a ketose derivative was postulated.
Hu
You-cai
YC
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Beijing, People's Republic of China.
Wu
Xian-fu
XF
Gao
Song
S
Yu
Shi-Shan
SS
Liu
Yue
Y
Qu
Jing
J
Liu
Jing
J
Liu
Yun-bao
YB
D007887:Fabaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010696:Phloroglucinol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
C518048:lysidicin A; C518049:lysidicin B; C518050:lysidicin C; D010696:Phloroglucinol