title: Basic characteristics of chronic hypotension cases: a longitudinal follow-up study from 1958 through 1999.
abstract: Few epidemiological studies have been conducted on the prevalence, blood pressure trends by age, and basic characteristics of chronic hypotension. Among 13,370 subjects (5,094 men and 8,276 women) examined from 1958 to 1999 in Japan, 92 were identified as chronic hypotensives (11 men and 81 women) whose systolic blood pressure (SBP, mmHg) was lower than 100 mmHg for 8 or more years. Trends of SBP and body mass index (BMI, kg/m2) were determined over a 16-year period in this group of chronic hypotensives and 276 age- and sex-matched controls (33 men and 243 women); during this 16-year period, the chronic hypotensives and controls ranged in age from 19 to 75 years. BMI, heart rate (HR, bpm), body temperature (degrees C), Hb (g/dl), and creatinine (Cre, mg/dl) were compared between the chronic hypotensives and the controls at the last examination. The chronic hypotensives had a female preponderance (0.2% in men and 1.0% in women, p=0.001), and their SBP and BMI increased little with increasing age. BMI (20.2+/-3.4), BMI-adjusted SBP (101+/-19), HR (63+/-10), body temperature (36.7+/-0.3), Hb (12.5+/-1.1), and Cre (0.81+/-0.13) were lower in the chronic hypotensives than those (22.9+/-3.4, 126+/-20, 68+/-10, 36.8+/-0.3, 12.9+/-1.1, and 0.86+/-0.12, respectively) in controls (p<0.05). The present results clearly show that chronic hypotensives have a female preponderance and low BMI, HR, body temperature, Hb, and Cre in addition to low SBP that does not increase with age.
authors.affiliation: Department of Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan. akahoshi@rerf.or.jp
authors.forename: Masazumi
authors.initials: M
authors.lastname: Akahoshi
authors.forename: Ayumi
authors.initials: A
authors.lastname: Hida
authors.forename: Misa
authors.initials: M
authors.lastname: Imaizumi
authors.forename: Midori
authors.initials: M
authors.lastname: Soda
authors.forename: Renju
authors.initials: R
authors.lastname: Maeda
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Ichimaru
authors.forename: Eiji
authors.initials: E
authors.lastname: Nakashima
authors.forename: Shinji
authors.initials: S
authors.lastname: Seto
authors.forename: Katsusuke
authors.initials: K
authors.lastname: Yano
mesh_terms: D000367:Age Factors; D000368:Aged; D015415:Biomarkers; D001772:Blood Cell Count; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D015992:Body Mass Index; D001831:Body Temperature / Q000502:physiology; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D005260:Female; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007022:Hypotension / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology; D007564:Japan / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009689:Nuclear Warfare; D012737:Sex Factors; D017741:Survivors
chemical_list: D015415:Biomarkers; D006454:Hemoglobins