title: Aging and innate immunity.
abstract: Adaptive immunity undergoes severe deterioration with age and represents the main problem in the elderly. However, evidence accumulated over the last decade supports the hypothesis that aging also has a profound impact on innate immunity, which in turn markedly impacts the health and longevity of older people.
authors.affiliation: Department of Cellular Biology, Physiology, and Immunology, University of Córdoba, E-14004 Córdoba, Spain. rsolana@uco.es
authors.forename: Rafael
authors.initials: R
authors.lastname: Solana
authors.forename: Graham
authors.initials: G
authors.lastname: Pawelec
authors.forename: Raquel
authors.initials: R
authors.lastname: Tarazona
mesh_terms: D000375:Aging / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate; D015398:Signal Transduction / Q000276:immunology*