Anterior uveitis, inflammatory bowel disease, and ankylosing spondylitis in a HLA-B27-positive woman.
A woman developed anterior uveitis at age 24, inflammatory bowel disease at age 29, and ankylosing spondylitis at age 45 by history. There were frequent recurrences. An HLA-B27 test was positive at age 53. The literature indicates that all of these conditions together in a HLA-B27-positive woman are uncommon. Physicians should be alert to the possibility that a patient might develop another of these associated diseases years after presentation of the first condition and educate their patients accordingly.
Singleton
E Mitchell
EM
Department of Ophthalmology, University of Arkansas for Medical, Sciences, Area Health Education Center-Northwest, Fayetteville, Arkansas, USA. eyedoc1@sbcglobal.net
Hutson
Sanford E
SE
D000328:Adult; D005260:Female; D015796:HLA-B27 Antigen / Q000097:blood / Q000276:immunology*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000276:immunology*; D013167:Spondylitis, Ankylosing / Q000276:immunology*; D014606:Uveitis, Anterior / Q000276:immunology*
D015796:HLA-B27 Antigen