title: NETGEN: generating phylogenetic networks with diploid hybrids.
abstract: CONCLUSIONS
  NetGen is an event-driven simulator that creates phylogenetic networks by extending the birth-death model to include diploid hybridizations. DNA sequences are evolved in conjunction with the topology, enabling hybridization decisions to be based on contemporary evolutionary distances. NetGen supports variable rate lineages, root sequence specification, outgroup generation and many other options. This note describes the NetGen application and proposes an extension of the Newick format to accommodate phylogenetic networks.
  
  
  BACKGROUND
  NetGen is written in C and is available in source form at http://www.phylo.unm.edu/~morin/.
authors.affiliation: Department of Computer Science, University of New Mexico, Albuquerque, NM, USA. morin@cs.unm.edu
authors.forename: M M
authors.initials: MM
authors.lastname: Morin
authors.forename: B M E
authors.initials: BM
authors.lastname: Moret
mesh_terms: D000465:Algorithms; D005075:Biological Evolution; D019070:Cell Lineage / Q000235:genetics*; D003198:Computer Simulation; D004171:Diploidy; D019143:Evolution, Molecular; D006822:Hybrid Cells / Q000502:physiology*; D008957:Models, Genetic; D010802:Phylogeny; D017422:Sequence Analysis, DNA / Q000379:methods*