title: Tubulo-interstitial nephritis and uveitis syndrome in a 6-year-old boy: case report.
abstract: A 6-year-old boy presented with a 4-month history of anorexia, weight loss and fatigue and was found to have tubulo-interstitial nephritis and uveitis (TINU) syndrome. After 2 months of corticosteroid therapy, resolution of the uveitis was almost complete but renal function showed only partial improvement. He was still in renal failure 6 months after diagnosis, but there was no relapse of the uveitis. Although the prognosis of TINU in children and adults is reported to be excellent, the outcome in young children can be less favourable, probably owing to delayed diagnosis and initiation of treatment.
authors.affiliation: Department of Pediatrics, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan. hamadanjm@yahoo.com
authors.forename: Jahed M
authors.initials: JM
authors.lastname: Hamdan
authors.forename: Fatima N
authors.initials: FN
authors.lastname: Obeidat
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000855:Anorexia / Q000209:etiology; D002648:Child; D005221:Fatigue / Q000209:etiology; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications* / Q000188:drug therapy; D015431:Weight Loss
chemical_list: D000305:Adrenal Cortex Hormones; D011239:Prednisolone; D011241:Prednisone