Living-related liver transplantation with removal of inferior vena cava for unresectable hepatoblastoma.
We report a case of a two-yr-old boy with hepatoblastoma resectable only by total hepatectomy including the vena cava. Successful LTx was performed with a living donor segment without vena cava reconstruction. The tumor was located in the bilateral lobe, surrounding the IVC. In spite of the high-dose chemotherapy, the tumor did not become resectable. LTx was performed using left lateral segment after removal of the IVC combined with total hepatectomy. Because the collaterals were well developed, the patient tolerated the procedure well. The serum AFP level decreased from 186 699 to 8 ng/mL in 11 months after LTx without local recurrence or distant metastasis.
Hasegawa
Toshimichi
T
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan. toshi@pedsurg.med.osaka-u.ac.jp
Kimura
Takuya
T
Ihara
Yoshiyuki
Y
Tazuke
Yuko
Y
Yoneda
Akihiro
A
Kusafuka
Takeshi
T
Fukuzawa
Masahiro
M
Okuyama
Hiroomi
H
Inoue
Masami
M
D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005220:Fathers; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D018197:Hepatoblastoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D011859:Radiography; D013997:Time Factors; D016896:Treatment Outcome; D014682:Vena Cava, Inferior / Q000601:surgery*
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide