title: Biochemical effects of nonylphenol polyethoxylate adjuvant, Diquat herbicide and their mixture on the three-spined stickleback (Gasterosteus aculeatus L.).
abstract: This study examined the response of 7-ethoxyresorufine-O-deethylase, glutathione-S-transferase, glutathione peroxidase, glutathione content, level of thiobarbituric acid reactive compounds and circulating vitellogenin, in three-spined sticklebacks after 21 days of exposure to Diquat herbicide, commercial nonylphenol polyethoxylate adjuvant and mixture between Diquat and adjuvant. The results showed that adjuvant exerted more important oxidative effects than Diquat and that mixture effects were unlike to single additivity. This study argues for ecotoxicological risk assessment of adjuvants and mixtures of adjuvants and pesticides.
authors.affiliation: National Institute of Industrial Environment and Risk (INERIS), Ecotoxicological Risk Assessment Unit, BP 2, F-60550 Verneuil en Halatte, France. wilfried.sanchez-Etudiant@ineris.fr
authors.forename: W
authors.initials: W
authors.lastname: Sanchez
authors.forename: O
authors.initials: O
authors.lastname: Palluel
authors.forename: L
authors.initials: L
authors.lastname: Lagadic
authors.forename: S
authors.initials: S
authors.lastname: Aït-Aïssa
authors.forename: J-M
authors.initials: JM
authors.lastname: Porcher
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis; D019363:Cytochrome P-450 CYP1A1 / Q000187:drug effects*; D003902:Detergents / Q000633:toxicity; D004178:Diquat / Q000633:toxicity*; D004781:Environmental Exposure; D005026:Ethylene Glycols / Q000633:toxicity*; D005260:Female; D005978:Glutathione / Q000032:analysis / Q000187:drug effects*; D005982:Glutathione Transferase / Q000187:drug effects*; D006540:Herbicides / Q000633:toxicity*; D008297:Male; D008782:Methylurea Compounds / Q000633:toxicity; D025341:Principal Component Analysis; D023701:Smegmamorpha / Q000378:metabolism*; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis; D014819:Vitellogenins / Q000097:blood; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D015415:Biomarkers; D003902:Detergents; D005026:Ethylene Glycols; D006540:Herbicides; D008782:Methylurea Compounds; D017392:Thiobarbituric Acid Reactive Substances; D014819:Vitellogenins; D014874:Water Pollutants, Chemical; C034222:methoxuron; C021754:terics; D004178:Diquat; D019363:Cytochrome P-450 CYP1A1; D005982:Glutathione Transferase; D005978:Glutathione