title: Evolution in the treatment of metastatic colorectal carcinoma of the liver.
abstract: Metastatic colorectal cancer to the liver is associated with a uniform poor prognosis without treatment. Advances in therapy over the past decades have now allowed surgical resections of the liver to occur with a low morbidity and mortality. Improvements in chemotherapy regimes have paralleled technical improvements and now allow a new group of patients to become eligible for surgical resection. This chapter will review the recent advances in surgical and chemotherapeutic regimes in metastatic colorectal cancer to the liver.
authors.affiliation: Department of Surgery, Section of Surgical Oncology, Yale University School of Medicine, Tompkins 202, 333 Cedar Street, New Haven, CT 06520, USA.
authors.forename: Charlotte-E
authors.initials: CE
authors.lastname: Ariyan
authors.forename: Ronald-R
authors.initials: RR
authors.lastname: Salem
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007260:Infusion Pumps; D008099:Liver / Q000187:drug effects / Q000601:surgery; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery*; D008297:Male; D020360:Neoadjuvant Therapy; D011379:Prognosis
chemical_list: D000970:Antineoplastic Agents