title: Isolated bilateral blindness as the sole manifestation of transient ischaemic attacks.
abstract: OBJECTIVE
  To explain the rare phenomenon of acute transient bilateral blindness without additional ophthalmological or neurological symptoms and signs.
  
  
  METHODS
  Six patients with isolated bilateral visual loss lasting 1-15 mins and occurring simultaneously in both eyes were evaluated. Clinical observation, neuroimaging (CT, MRI, MR-angiography), extra- and transcranial Doppler and vascular risk factors assessment were performed.
  
  
  RESULTS
  Cortical blindness due to bilateral occipital lobe transient ischaemic attacks (TIAs) was established as the most likely cause of acute transient visual loss in all patients.
  
  
  CONCLUSIONS
  We suggest that in cases of transient bilateral blindness with sudden onset, appearing simultaneously in both visual fields, a bilateral ischaemia of the visual cortex should be suspected even if other neurological symptoms are lacking. Patients should be managed in the same way as patients with vertebrobasilar TIAs.
authors.affiliation: Department of Neurology, Martin-Luther-University Halle-Wittenberg, Halle, Saale, Germany. michael.krasnianski@medizin.uni-halle.de
authors.forename: Michael
authors.initials: M
authors.lastname: Krasnianski
authors.forename: Viktoria
authors.initials: V
authors.lastname: Bau
authors.forename: Stephan
authors.initials: S
authors.lastname: Neudecker
authors.forename: Alfred
authors.initials: A
authors.lastname: Lindner
authors.forename: Stephan
authors.initials: S
authors.lastname: Zierz
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D019575:Blindness, Cortical / Q000175:diagnosis / Q000209:etiology*; D002560:Cerebrovascular Circulation; D005260:Female; D007839:Functional Laterality; D006801:Humans; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000175:diagnosis; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D017585:Ultrasonography, Doppler, Transcranial; D014793:Visual Cortex / Q000473:pathology