An ongoing pregnancy after frozen thawed embryo transfer in a patient with Klinefelter's syndrome.
BACKGROUND
Pregnancy following frozen thawed embryo transfer in a patient with nonmosaic Klinefelter's syndrome is extremely rare. A healthy ongoing pregnancy achieved with frozen thawed embryo transfer in a patient with nonmosaic Klinefelter's syndrome was described.


METHODS
A case report from a tertiary center for assisted reproductive technologies. A 34-year-old man with azoospermia and nonmosaic Klinefelter's syndrome and his 26-year-old wife presented with primary infertility of 8 years' duration. Frozen thawed embryo transfer following intracytoplasmic sperm injection using surgically retrieved spermatozoa was performed.


RESULTS
A healthy ongoing pregnancy with a normal 46,XY karyotype was achieved with day 3 frozen thawed embryo transfer.


CONCLUSIONS
Frozen thawed embryo transfer may be a viable option to achieve pregnancy in patients with Klinefelter's syndrome.
Yarali
Hakan
H
Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey. hyarali@hacettepe.edu.tr
Bozdag
Gurkan
G
D000328:Adult; D053713:Azoospermia / Q000209:etiology / Q000628:therapy*; D015925:Cryopreservation; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007713:Klinefelter Syndrome / Q000503:physiopathology*; D008297:Male; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic; D053625:Sperm Retrieval