Efficiency of changing the embryo transfer time from day 3 to day 2 among women with poor ovarian response: a prospective randomized trial.
OBJECTIVE
To compare the outcome of day 2 and day 3 embryo transfers in women demonstrating poor ovarian response.


METHODS
Prospective randomized clinical trial.


METHODS
Private assisted reproductive technology center.


METHODS
Two hundred eighty-one women demonstrating poor ovarian response to controlled ovarian hyperstimulation.


METHODS
Women who were poor responders were randomly allocated to day 2 or day 3 embryo transfer following oocyte retrieval.


METHODS
Implantation rates and pregnancy rates per oocyte retrieval and embryo transfer.


RESULTS
The clinical pregnancy rates per oocyte retrieval (37.2% vs. 21.4%, respectively; P<.05) and per embryo transfer (38.9% vs. 24.1%, respectively; P<.05) were significantly higher in the day 2 embryo transfer group compared with day 3. On the other hand, implantation rates were not different between groups (23.9% vs. 17.2%, respectively; P=.08).


CONCLUSIONS
Our results demonstrated that transfering embryos on day 2 could provide an alternative to the management of poor responder patients.
Bahceci
Mustafa
M
Bahceci Women Health Care Center and German Hospital in Istanbul, Istanbul, Turkey. mbahceci@superonline.com
Ulug
Ulun
U
Ciray
H Nadir
HN
Akman
Mehmet Ali
MA
Erden
Halit Firat
HF
D000328:Adult; D004624:Embryo Transfer / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology* / Q000628:therapy*; D010062:Ovulation Induction / Q000706:statistics & numerical data*; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D017211:Treatment Failure; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology