Knowing 7 x 8, but not the meaning of 'elephant': evidence for the dissociation between numerical and non-numerical semantic knowledge.
Patients affected by semantic dementia (SD) and other severe cognitive deficits may show preserved numerical skills, including the retrieval of multiplication facts from long-term memory. No studies so far specifically investigated the network of arithmetic facts in semantic dementia. Thus, it is unknown whether preserved multiplication in SD truly reflects intact semantic knowledge or preserved retrieval of verbal sequences (just as the recitation of rhymes or poems). In the present study a patient (SG) with SD underwent an extensive assessment of number processing and calculation abilities. In particular, multiplication knowledge was investigated through a series of computerised tasks (production task, multiple-choice task, number bisection task with multiplicative triplets, number-matching task). SG demonstrated excellent performance in all number processing and calculation tasks. In computerised tasks tapping multiplication fact knowledge, SG was as accurate and fast as healthy controls. Analyses on individual regression slopes indicated that SG's reaction time effects (problem-size effect, problem-difficulty effect, interference effects, and facilitation effect) were comparable to those found in controls in each task. These results add new evidence to the independence of numerical knowledge from other semantic information and provide further insight into the organisation of stored arithmetic knowledge.
Zamarian
L
L
Department of Psychology, University of Trieste, Via Sant'Anastasio, 12, 34134 Trieste, Italy. zamarian@psico.units.it
Karner
E
E
Benke
T
T
Donnemiller
E
E
Delazer
M
M
D003704:Dementia / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D004213:Dissociative Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008433:Mathematics; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D009633:Nonverbal Communication; D011930:Reaction Time / Q000502:physiology; D012660:Semantics; D015899:Tomography, Emission-Computed, Single-Photon