title: Frequencies of the four major Amerindian mtDNA haplogroups in the population of Montevideo, Uruguay.
abstract: mtDNA Amerindian polymorphisms were studied in 108 inhabitants of Montevideo, Uruguay, using PCR RFLP analysis. Amerindian haplogroups were found in 20.4% of the sample. The frequency of Amerindian polymorphisms in Montevideo differed significantly from that observed in Tacuarembó, a city about 400 km away, indicating the high level of variation within Uruguay. Results for mitochondrial markers indicate that admixture occurred primarily as a result of Amerindian females mating with European males.
authors.affiliation: Departamento de Citogenética, Instituto de Investigaciones Biológicas Clemente Estable, Av. Italia 3318, CP 11600, Montevideo, Uruguay.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Gascue
authors.forename: Adriana
authors.initials: A
authors.lastname: Mimbacas
authors.forename: Monica
authors.initials: M
authors.lastname: Sans
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Gallino
authors.forename: Bernardo
authors.initials: B
authors.lastname: Bertoni
authors.forename: Pedro
authors.initials: P
authors.lastname: Hidalgo
authors.forename: Horacio
authors.initials: H
authors.lastname: Cardoso
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics*; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D008297:Male; D008928:Mitochondria; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D014583:Uruguay
chemical_list: D004272:DNA, Mitochondrial