Electrochemical behaviour of 2,8-dihydroxyadenine at a glassy carbon electrode.
The electrochemical behaviour of 2,8-dihydroxyadenine (2,8-DHA)- the main adenine oxidation product- has been investigated over a wide pH range at a glassy carbon electrode (GCE) using cyclic, differential pulse and square wave voltammetry. The oxidation of 2,8-DHA is a quasi-reversible process, pH dependent and occurs with the formation of a main oxidation product, P(2,8-DHA), that strongly adsorbs on the electrode surface. The reduction of 2,8-DHA also occurs and is a reversible process in the absence of molecular oxygen. In electrolytes with pH between 4 and 9 two consecutive reversible charge transfer reactions were identified. However, it was observed that O(2) interfered with the reductive electron transfer process of 2,8-DHA and that, in the presence of oxygen, the reduction of 2,8-DHA occurs at less negative potentials than in the absence of oxygen.
Diculescu
Victor C
VC
Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal.
Piedade
Jose Antonio P
JA
Oliveira-Brett
Ana Maria
AM
D000225:Adenine / Q000031:analogs & derivatives* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D005898:Glass / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D009994:Osmolar Concentration; D010084:Oxidation-Reduction; D012996:Solutions
D012996:Solutions; C002993:2,8-dihydroxyadenine; D002244:Carbon; D000225:Adenine