Periodontal disease and atherosclerosis from the viewpoint of the relationship between community periodontal index of treatment needs and brachial-ankle pulse wave velocity.
BACKGROUND
It has been suggested that periodontal disease may be an independent risk factor for the development of atherosclerosis. However, the relationship between periodontal disease and atherosclerosis has not been fully elucidated. This study aimed to assess the effects of periodontal disease on atherosclerosis.


METHODS
The study design was a cross-sectional study. Subjects were 291 healthy male workers in Japan. We used the Community Periodontal Index of Treatment Needs (CPITN) score, average probing depth and gingival bleeding index (rate of bleeding gums) to assess the severity of periodontal disease. We also used the Brachial-Ankle Pulse Wave Velocity (baPWV) as the index for the development of atherosclerosis.


RESULTS
The unadjusted odds ratio (OR) of atherosclerosis in relation to the CPITN score was 1.41 [95% CI: 1.16-1.73]. However, after adjustment for age, systolic blood pressure and smoking, the CPITN score had no relationship with atherosclerosis (adjusted OR: 0.91 [0.68-1.20]).


CONCLUSIONS
Our results show no relationship between mild periodontal disease and atherosclerosis after appropriate adjustments.
Miyaki
Koichi
K
Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan. miyaki@sc.itc.keio.ac.jp
Masaki
Katsunori
K
Naito
Mariko
M
Naito
Toru
T
Hoshi
Keika
K
Hara
Asako
A
Tohyama
Shugo
S
Nakayama
Takeo
T
D000328:Adult; D000842:Ankle / Q000098:blood supply; D050197:Atherosclerosis / Q000453:epidemiology / Q000209:etiology*; D001783:Blood Flow Velocity; D001916:Brachial Artery / Q000502:physiology; D002617:Chemical Industry; D003430:Cross-Sectional Studies; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010510:Periodontal Diseases / Q000150:complications* / Q000453:epidemiology; D010512:Periodontal Index; D011673:Pulsatile Flow; D012307:Risk Factors