Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
A 20-year-old man was admitted to our hospital for treatment of verapamil sensitive idiopathic left ventricular tachycardia (ILVT). During the electrophysiologic study (EPS), no sustained ventricular tachycardia (VT) could be induced both at baseline and after infusion of isoproterenol. However, sustained clinical VT could be easily induced with single ventricular extrastimulation following intravenous administration of pilsicainide, a class Ic sodium channel blocker. The arrhythmia was ablated with radiofrequency catheter ablation.
Nagai
Takayuki
T
Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, Japan.
Suyama
Kazuhiro
K
Shimizu
Wataru
W
Noda
Takashi
T
Satomi
Kazuhiro
K
Kurita
Takashi
T
Aihara
Naohiko
N
Kamakura
Shiro
S
D000328:Adult; D000889:Anti-Arrhythmia Agents; D004338:Drug Combinations; D004562:Electrocardiography; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives*; D008297:Male; D017180:Tachycardia, Ventricular / Q000150:complications / Q000175:diagnosis*; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis*; D014700:Verapamil
D000889:Anti-Arrhythmia Agents; D004338:Drug Combinations; D008012:Lidocaine; C042288:pilsicainide; D014700:Verapamil