title: Inhalation induction using sevoflurane in children: the single-breath vital capacity technique compared to the tidal volume technique*.
abstract: The single-breath vital capacity technique is suitable for inhalation induction of anaesthesia, using sevoflurane in children aged > 5 years. The purpose of this randomised trial was to compare the single breath vital capacity technique with the conventional tidal volume technique. Seventy- three ASA 1 or 2 children were instructed during the pre-operative visit in the vital capacity technique. The main criterion measured was time to loss of the eyelash reflex. Induction was performed using a circle-absorber breathing circuit primed with sevoflurane 7% in 50% nitrous oxide/oxygen with 6 l.min(-1) fresh gas flow. Time required for induction, haemodynamic changes, airway tolerance and side-effects were recorded. The children's opinion on the technique used was scored using a visual analogue scale (0-100) and a Smiley scale (0-10). The time to loss of the eyelash reflex was found to be reduced in the vital capacity group compared to the tidal volume group. The time to central myosis, to achieve bispectral index values 60 and 40, haemodynamic changes, respiratory events and side-effect incidences were similar in both groups. However, we found that the vital capacity technique was preferred by the children to the tidal volume technique.
authors.affiliation: Service of Anaesthesiology, Hôtel-Dieu, CHU Nantes, France. corinne.lejus@chu-nantes.fr
authors.forename: C
authors.initials: C
authors.lastname: Lejus
authors.forename: V
authors.initials: V
authors.lastname: Bazin
authors.forename: M
authors.initials: M
authors.lastname: Fernandez
authors.forename: J M
authors.initials: JM
authors.lastname: Nguyen
authors.forename: A
authors.initials: A
authors.lastname: Radosevic
authors.forename: M F
authors.initials: MF
authors.lastname: Quere
authors.forename: C
authors.initials: C
authors.lastname: Le Roux
authors.forename: A
authors.initials: A
authors.lastname: Le Corre
authors.forename: M
authors.initials: M
authors.lastname: Pinaud
mesh_terms: D000769:Anesthesia, Inhalation / Q000009:adverse effects / Q000379:methods; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D001767:Blinking / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D017060:Patient Satisfaction; D012120:Respiration Disorders / Q000139:chemically induced; D000077149:Sevoflurane; D013990:Tidal Volume; D013997:Time Factors; D014797:Vital Capacity
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane