title: New pulmonary infiltrates in a 19 year-old with sickle cell crisis.
abstract: OBJECTIVE
  Sickle cell anemia (SCA) is the most common inherited blood disorder. Sickle cell crisis is characterized by episodes of pain, chronic hemolytic anemia and severe infections, usually beginning in early childhood. Sickle cell disease primarily affects those of African descent and Hispanics of Caribbean ancestry, but the trait has also been found in those with Middle Eastern, Indian, Latin American, Native American, and Mediterranean heritage. Recent studies indicate that more than 12,500 people in England have sickle cell disorders. The acute chest syndrome is the leading cause of death and the second most common cause of hospitalization among patients with sickle cell disease. The acute chest syndrome (ACS) is characterized by chest pain with dyspnea and recent radiological abnormalities. Since its cause is largely unknown, rapid recognition and early institution of therapy is paramount as with timely and appropriate intervention majority of these patients survive. The treatment of ACS rests on controlled hydration, antibiotic therapy, oxygen therapy, controlled analgesic therapy, blood transfusion and exchange transfusion. A better understanding of the disease and a close collaborative approach between a primary care physician and a specialist may be the key to improve the quality of care rendered.
  
  
  METHODS
  Research studies, review articles, and published scientific meeting abstracts were reviewed.
authors.affiliation: Division of Internal Medicine, Mercy Catholic Medical Center, Drexel University College of Medicine, Pennsylvania 19018, USA. tasbirul@msn.com
authors.forename: Tasbirul
authors.initials: T
authors.lastname: Islam
authors.forename: Md Haris Umer
authors.initials: MH
authors.lastname: Usman
authors.forename: Fahd
authors.initials: F
authors.lastname: Rahman