Supramolecular chiral recognition by bischlorins: a two-point interaction mode combined with the host's conformational modulation controlled by the guest's stereochemistry and bulkiness.
[reaction: see text] Supramolecular chiral recognition based on two-point host-guest interactions coupled with the different host's conformational response using the enantiopure bischlorin hosts and different antipodal amine guests is reported. The bulkiness at the guest's stereogenic center controls the chiral recognition properties resulting in switching of the enantioselectivity.
Borovkov
Victor V
VV
Entropy Control Project, ICORP, JST, Toyonaka-shi, Osaka, Japan. victrb@inoune.jst.go.jp
Inoue
Yoshihisa
Y