In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy?
Killeen
O G
OG
Paediatric Rheumatology, Department of Child Health, RHSC, Glasgow, UK. orlakilleen@doctors.org.uk
Gardner-Medwin
J M
JM
D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D002648:Child; D019587:Dietary Supplements; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D005493:Folic Acid Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use
D018501:Antirheumatic Agents; D005493:Folic Acid Antagonists; D005492:Folic Acid; D008727:Methotrexate