title: [Thirteen cases of intrahepatic biliary cystadenoma and cystadenocarcinoma: a single center experience].
abstract: OBJECTIVE
  Biliary cystadenoma (BCA) and biliary cystadenocarcinoma (BCACa) are rare cystic neoplasms that usually arise from the liver. We reviewed the clinicopathologic and radiologic findings of 13 cases of intrahepatic biliary cystic neoplasms.
  
  
  METHODS
  Seven patients with BCA and 6 patients with BCACa which were pathologically proven within past 10 years were included in this retrospective study.
  
  
  RESULTS
  BCA (7 of 7) was more common in female compared to BCACa (4 of 6). Mean age at diagnosis was 53.4 years (BCA) and 58.5 years (BCACa). Abdominal pain (54%) was the most common presenting symptom. Eleven patients (61.5%) exhibited normal liver function profiles and 5 patients (38%) showed elevated levels of serum CA19-9 levels (mean 894.2 U/mL, range: 78.7-2,080). Mean size of tumor was 11.7 cm (range: 5-15). Most frequent radiologic finding was a single cystic mass with septation. BCACa tended to have intracystic solid portion. The cut surface revealed a unilocular or multilocular cystic mass with mucinous contents. Complete surgical excision was done in 12 patients. After the complete resection, recurrence was observed in 1 case of BCACa.
  
  
  CONCLUSIONS
  The possibility of biliary cystic neoplasm should be suspected when an intrahepatic cystic lesion with multiseptation or solid portion is noted on imaging study. In addition, complete excision for definite diagnosis and treatment need to be performed.
authors.affiliation: Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Tae Hoon
authors.initials: TH
authors.lastname: Oh
authors.forename: Myung Hwan
authors.initials: MH
authors.lastname: Kim
authors.forename: Sung Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Dong Wan
authors.initials: DW
authors.lastname: Seo
authors.forename: Sang Soo
authors.initials: SS
authors.lastname: Lee
authors.forename: Eui Young
authors.initials: EY
authors.lastname: Kim
authors.forename: Ju Hyung
authors.initials: JH
authors.lastname: Song
authors.forename: Ji Hoon
authors.initials: JH
authors.lastname: Jung
authors.forename: Sang Ah
authors.initials: SA
authors.lastname: Lee
authors.forename: Sung Gyu
authors.initials: SG
authors.lastname: Lee
authors.forename: So Hyung
authors.initials: SH
authors.lastname: Park
authors.forename: Se Jin
authors.initials: SJ
authors.lastname: Jang
mesh_terms: D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery; D001653:Bile Ducts, Intrahepatic; D003536:Cystadenocarcinoma / Q000473:pathology / Q000601:surgery; D003537:Cystadenoma / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged