title: Class 1 integrons in resistant Escherichia coli and Klebsiella spp., US hospitals.
abstract: We examined Escherichia coli and Klebsiella spp. from US hospitals for class 1 integrons. Of 320 isolates, 181 (57%) were positive; association of integrons with resistance varied by drug and organism. Thus, determining integron epidemiology will improve understanding of how antibacterial resistance determinants spread in the United States.
authors.affiliation: Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Aarati N
authors.initials: AN
authors.lastname: Rao
authors.forename: Miriam
authors.initials: M
authors.lastname: Barlow
authors.forename: Leigh Ann
authors.initials: LA
authors.lastname: Clark
authors.forename: John R
authors.initials: JR
authors.lastname: Boring
authors.forename: Fred C
authors.initials: FC
authors.lastname: Tenover
authors.forename: John E
authors.initials: JE
authors.lastname: McGowan
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D006761:Hospitals; D006801:Humans; D032023:Integrons / Q000235:genetics*; D007709:Klebsiella / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D007710:Klebsiella Infections / Q000382:microbiology*; D016015:Logistic Models; D008826:Microbial Sensitivity Tests; D015999:Multivariate Analysis; D016133:Polymerase Chain Reaction; D014481:United States / Q000453:epidemiology
chemical_list: D004269:DNA, Bacterial