title: Primary hyperaldosteronism: effect of adrenal vein sampling on surgical outcome.
abstract: OBJECTIVE
  Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism.
  
  
  METHODS
  Retrospective review.
  
  
  METHODS
  University medical center.
  
  
  METHODS
  Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism.
  
  
  METHODS
  We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes.
  
  
  RESULTS
  Mean +/- SEM adrenal nodule size was 1.54 +/- 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia.
  
  
  CONCLUSIONS
  Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.
authors.affiliation: Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75390-9156, USA. fiemu.nwariaku@utsouthwestern.edu
authors.forename: Fiemu E
authors.initials: FE
authors.lastname: Nwariaku
authors.forename: Barbra S
authors.initials: BS
authors.lastname: Miller
authors.forename: Richard
authors.initials: R
authors.lastname: Auchus
authors.forename: Shelby
authors.initials: S
authors.lastname: Holt
authors.forename: Lori
authors.initials: L
authors.lastname: Watumull
authors.forename: Bart
authors.initials: B
authors.lastname: Dolmatch
authors.forename: Shawna
authors.initials: S
authors.lastname: Nesbitt
authors.forename: Wanpen
authors.initials: W
authors.lastname: Vongpatanasin
authors.forename: Ronald
authors.initials: R
authors.lastname: Victor
authors.forename: Frank
authors.initials: F
authors.lastname: Wians
authors.forename: Edward
authors.initials: E
authors.lastname: Livingston
authors.forename: William H
authors.initials: WH
authors.lastname: Snyder
mesh_terms: D000311:Adrenal Glands / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000601:surgery; D000315:Adrenalectomy; D000450:Aldosterone / Q000097:blood; D002406:Catheterization, Peripheral; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014680:Veins
chemical_list: D000450:Aldosterone