The impact of genomics on discovering drugs against infectious diseases.
Genomics is accelerating the progress in data generation and interpretation in the global analyses of components of cells, including the spectrum of lipids, RNA, metabolites, proteins, mutational phenotypes or DNA methylation sites. Integration of the knowledge generated by these diverse strategies is predicted to have a tremendous impact on approaches to rational drug discovery against infectious diseases.
Boshoff
Helena I M
HI
National Institutes of Health, Tuberculosis Research Section, LIG/NIAID/NIH, Twinbrook II, Room 239, 12441 Parklawn Drive, Rockville, MD 20852, USA. hboshoff@niaid.nih.gov
Manjunatha
Ujjini H
UH
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D003141:Communicable Diseases / Q000188:drug therapy* / Q000235:genetics; D015195:Drug Design; D023281:Genomics; D006801:Humans; D010597:Pharmacogenetics; D049490:Systems Biology / Q000379:methods
D000890:Anti-Infective Agents