Neuroborreliosis in an HIV-1 positive patient.
Simultaneous co-infections of Borrelia burgdorferi sensu lato and HIV-1 are rare events, with only six published cases. A case of acute neuroborreliosis with facial palsy, meningoradiculitis (Bannwarth's syndrome) in an HIV-1 positive individual is described. Diagnosis was confirmed by Western immunoblot analysis of serum and CSF and by proof of intrathecal production of antibodies against B. garinii. The patient was successfully treated with cefotaxime. In all published HIV+ cases, the course of borreliosis did not differ from that of the HIV negative population and the prognosis in properly treated patients was good.
Cerný
R
R
Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine, V Uvalu 84, 15006 Praha 5, Czech Republic. rudolf.cerny@lfmotol.cuni.cz
Machala
L
L
Bojar
M
M
Rozsypal
H
H
Pícha
D
D
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood / Q000134:cerebrospinal fluid; D015748:Borrelia burgdorferi Group / Q000302:isolation & purification*; D002439:Cefotaxime / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000276:immunology; D015658:HIV Infections / Q000150:complications* / Q000821:virology; D015497:HIV-1 / Q000302:isolation & purification; D006801:Humans; D020852:Lyme Neuroborreliosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D002439:Cefotaxime