Eukaryotic transcription: what does it mean for a gene to be 'on'?
Until recently, transcription could only be observed by measuring mRNA production of cell populations, thus obscuring the kinetics at the level of individual transcription events. A new study now shows that eukaryotic transcription, visualised in individual living cells, occurs in bursts -- much as it does in prokaryotes.
Golding
Ido
I
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA. igolding@princeton.edu
Cox
Edward C
EC
D000818:Animals; D004023:Dictyostelium / Q000378:metabolism*; D005057:Eukaryotic Cells / Q000378:metabolism*; D050437:Genes, Developmental; D007700:Kinetics; D014158:Transcription, Genetic