Asymmetric hydrogenation of quinolines catalyzed by iridium complexes of BINOL-derived diphosphonites.
A chiral diphosphonite, derived from BINOL and with an achiral diphenyl ether backbone, is an excellent ligand for the Ir-catalyzed asymmetric hydrogenation of quinolines; achiral P-ligands serving as possible additives (ee = 73-96%).
Reetz
Manfred T
MT
Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany. reetz@mpi-muelheim.mpg.de
Li
Xiaoguang
X