title: Exophiala dermatitidis keratitis after laser in situ keratomileusis.
abstract: A 52-year-old man had laser in situ keratomileusis in March 2002 and 2 weeks later had a corneal infection that was found to be caused by Exophiala dermatitidis. This infection waxed and waned for 9 months despite therapy with natamycin, itraconazole, and fluconazole but eventually responded to topical amphotericin. He recovered good visual acuity in this eye with a rigid gas-permeable lens. This case shows the importance of selecting the appropriate agent in fungal keratitis.
authors.affiliation: Cornea Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Seema R
authors.initials: SR
authors.lastname: Patel
authors.forename: Kristin M
authors.initials: KM
authors.lastname: Hammersmith
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Rapuano
authors.forename: Elisabeth J
authors.initials: EJ
authors.lastname: Cohen
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D005093:Exophiala / Q000302:isolation & purification*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D020731:Keratomileusis, Laser In Situ; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D009216:Myopia / Q000601:surgery; D011183:Postoperative Complications; D012008:Recurrence
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B