title: Endoscopic band ligation therapy for upper gastrointestinal bleeding related to Mallory-Weiss syndrome.
abstract: BACKGROUND
  No consensus exists as to the best endoscopic treatment for Mallory-Weiss syndrome. Endoscopic band ligation is a readily available and easily learned technique. This prospective study evaluated the efficacy and safety of endoscopic band ligation therapy for Mallory-Weiss syndrome.
  
  
  METHODS
  From August 1998 to June 2005, a clinical trial assessed 37 patients with a diagnosis of Mallory-Weiss syndrome who had active bleeding, exposed vessels, or both. Their lesions were treated using endoscopic band ligation.
  
  
  RESULTS
  Endoscopic band ligation was successful in 36 of 37 cases, with a follow-up period ranging from 1 to 24 months. The remaining patient had severe liver failure and disseminated intravascular coagulation. The patient bled again at 12 h and subsequently died. Except for this case, no recurrent bleeding, perforation, or other complications occurred.
  
  
  CONCLUSIONS
  The study results suggest that endoscopic band ligation is an effective, safe, and easily learned procedure for treating upper gastrointestinal bleeding related to Mallory-Weiss syndrome.
authors.affiliation: Department of Gastroenterology, Aso Iizuka Hospital, 3-83 Yoshio, Iizuka, Fukuoka, 820-8505, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Higuchi
authors.forename: K
authors.initials: K
authors.lastname: Akahoshi
authors.forename: Y
authors.initials: Y
authors.lastname: Sumida
authors.forename: M
authors.initials: M
authors.lastname: Kubokawa
authors.forename: Y
authors.initials: Y
authors.lastname: Motomura
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Nawata
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004211:Disseminated Intravascular Coagulation / Q000150:complications; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008026:Ligation / Q000009:adverse effects / Q000379:methods; D017093:Liver Failure / Q000150:complications; D008297:Male; D008309:Mallory-Weiss Syndrome / Q000150:complications*; D008875:Middle Aged; D011446:Prospective Studies; D012008:Recurrence; D016896:Treatment Outcome