Malignant peripheral nerve sheath tumor of breast in patient without Von Recklinghausen's neurofibromatosis: a case report.
Malignant peripheral nerve sheath tumor (MPNST) of the breast without Von Recklinghausen's neurofibromatosis (VRN) is extremely rare. The authors report a 19 year-old woman who presented with a 12 month history of a painless mass of the left breast. Tissue biopsy was performed. The histologic diagnosis was made with immunohistochemical study in which the tumor showed positivity of vimentin, S-100 protein, neuron-specific protein(NSE), neurofilament protein(NF) and glial fibrillary acidic protein(GFAP). The patient was referred for radiation therapy after simple mastectomy.
Thanapaisal
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Department of Surgery, Faculty of Medicine, Khon Kaen University, Thailand. chaiyut06@yahoo.com
Koonmee
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Siritunyaporn
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S
D000328:Adult; D001706:Biopsy; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D018317:Nerve Sheath Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009455:Neurofibroma / Q000175:diagnosis; D011379:Prognosis; D035583:Rare Diseases; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins; D014746:Vimentin