Food protein sensitivity with partial villous atrophy after pediatric liver transplantation with tacrolimus immunosuppression.
We report three pediatric liver transplant recipients receiving tacrolimus immunosuppression presented with vomiting, heme-positive stools and failure to thrive, who had subtotal villous atrophy in their histology because of food protein sensitivity. Case findings and current literature of the casual relationship between tacrolimus and food allergies briefly reviewed.
Blanchard
Samra Sarigol
SS
Department of Pediatric Gastroenetrology, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA.
Gerrek
Marla
M
Czinn
Steve
S
Chelimsky
Gisela
G
Seaman
David
D
Siegel
Christopher
C
Splawski
Judy
J
D002102:Cadaver; D002648:Child; D002675:Child, Preschool; D004382:Duodenitis / Q000209:etiology / Q000473:pathology*; D004724:Endoscopy; D005260:Female; D005512:Food Hypersensitivity; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007223:Infant; D016031:Liver Transplantation / Q000276:immunology*; D008297:Male; D016559:Tacrolimus / Q000009:adverse effects*; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D016559:Tacrolimus