Oral and intralesional steroid therapy in giant cell granuloma.
Giant cell granulomas account for 7% of all benign tumors of the jaw. They are commonly seen as asymptomatic masses. A 4-year-old boy with an exophitic, crusty, hemorrhagic mass on the anterolateral region of the right maxilla was referred to our department. Pathological examination was reported as giant cell granuloma. A mixture of prednisolone, lidocaine and adrenaline was injected intralesionally once a week and oral fluocortone was added to this therapy. A limited surgery could be performed. Intralesional prednisolone and systemic fluocortone therapy seems to be effective, as the lesion stopped growing and increase in bony structures was observed radiologically.
Comert
Ela
E
Otorhinolaryngology Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey. elacomert@yahoo.com
Turanli
Mehmet
M
Ulu
Sahin
S
D000284:Administration, Oral; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage; D005448:Fluocortolone / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D015552:Injections, Intralesional; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008439:Maxillary Diseases / Q000188:drug therapy* / Q000601:surgery; D011239:Prednisolone / Q000008:administration & dosage*
D005448:Fluocortolone; D008012:Lidocaine; D011239:Prednisolone; D004837:Epinephrine