title: Plasma-binding globulins and acute stress response.
abstract: Within studies of acute stress physiology an increase in glucocorticoid secretion is thought to be the primary mediator of tissue response to stress. Corticosteroid-binding globulin may regulate tissue availability of steroids, but has not been considered a dynamic component of the acute stress response. Here, we examined CBG level over the common 60-minute time frame in an acute capture and handling protocol to investigate whether CBG capacity is dynamic or static over short stressors. Using a comparative approach, we measured CBG response to capture and handling stress in nine species of birds, representing five orders and nine families. CBG capacity significantly declined within 30 - 60 minutes of capture in five of the nine species examined. This decline may serve to significantly increase the level of corticosterone reaching tissues during acute stress.
authors.affiliation: Integrative Biology, University of Texas at Austin, USA. creagh@montana.edu
authors.forename: C W
authors.initials: CW
authors.lastname: Breuner
authors.forename: S E
authors.initials: SE
authors.lastname: Lynn
authors.forename: G E
authors.initials: GE
authors.lastname: Julian
authors.forename: J M
authors.initials: JM
authors.lastname: Cornelius
authors.forename: B J
authors.initials: BJ
authors.lastname: Heidinger
authors.forename: O P
authors.initials: OP
authors.lastname: Love
authors.forename: R S
authors.initials: RS
authors.lastname: Sprague
authors.forename: H
authors.initials: H
authors.lastname: Wada
authors.forename: B A
authors.initials: BA
authors.lastname: Whitman
mesh_terms: D000210:Acute-Phase Reaction / Q000097:blood*; D000818:Animals; D001717:Birds / Q000097:blood* / Q000502:physiology; D001824:Body Constitution; D046091:Charadriiformes / Q000097:blood; D003345:Corticosterone / Q000097:blood; D046093:Falconiformes / Q000097:blood; D005260:Female; D046369:Finches / Q000097:blood; D046094:Galliformes / Q000097:blood; D006234:Handling, Psychological; D008297:Male; D046109:Passeriformes / Q000097:blood; D010802:Phylogeny; D013312:Stress, Physiological; D013997:Time Factors; D014156:Transcortin / Q000378:metabolism*
chemical_list: D014156:Transcortin; D003345:Corticosterone