[Kawasaki disease: heart disease during childhood].
The aim of this study was to determine risk factors for coronary lesions, the type of heart lesion present, and long-term outcome in Kawasaki disease. We studied 150 children, aged 3 months to 9.5 years, who met the criteria for a diagnosis of Kawasaki disease. Of the 18% who were diagnosed with heart disease, 100% had coronary artery abnormalities, 11.1% had pancarditis, and 3.7%, mitral insufficiency. The coronary abnormalities were classified according severity as follows: diffuse ectasia in 40.7%; a small-to-medium-sized solitary coronary artery aneurysm in 33.3%; numerous small-to-medium-sized aneurysms in 11.1%; giant aneurysms in 11.1%; and coronary artery stenosis in 3.7%. The presence of pancarditis was a predictor of a giant coronary artery aneurysm. Mortality was 3.7%. Coronary aneurysm was the predominant heart lesion. The risk factors for coronary aneurysm in Kawasaki disease included age less than 27 months, fever lasting more than 8 days, erythrocyte sedimentation greater than 70 mm, and pancarditis.
Schroh
Ana M
AM
Servicio de Cardiología Infantil, Hospital Pediátrico Dr. Humberto J. Notti, Mendoza, Argentina. schroh_md@hotmail.com
Domínguez
Pablo
P
Laghezza
Lidia B
LB
Melonari
Pablo A
PA
Olguín
Marisa
M
Miatello
Roberto
R
D002648:Child; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*