title: Association between clinical characteristics, computed tomography characteristics, and histologic diagnosis for cats with sinonasal disease.
abstract: The purpose of this retrospective study was to determine the association between clinical characteristics, computed tomography (CT) characteristics, and histologic diagnosis in 43 cats with sinonasal disease. All cats were evaluated with CT and nasopharyngeal endoscopic examination, with histologic diagnosis based on nasal biopsy. Fifteen cats were diagnosed with sinonasal neoplasia and 28 cats were diagnosed with rhinitis. Clinical characteristics determined to be significantly associated with neoplasia were unilateral ocular discharge (odds ratio [OR] 9.6) and the presence of a nasopharyngeal mass during endoscopic examination (OR 18.9). CT characteristics found to be significantly associated with neoplasia included: unilateral lysis of ethmoturbinates (OR 11.0), unilateral lysis of the dorsal (OR 8.3) and lateral maxilla (OR 6.9), lysis of the vomer bone (OR 6.7) and ventral maxilla (OR 28.8), and bilateral lysis of the orbital lamina (OR 4.1); unilateral abnormal soft tissue/fluid within the sphenoid sinus (OR 15.3), frontal sinus (OR 10.4), and/or and retrobulbar space (OR 12.2). Lysis of the maxillary turbinates, nasal septum, nasal bone, palatine bone, and cribriform plate were not significantly associated with sinonasal neoplasia.
authors.affiliation: Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA. tromblee@vt.edu
authors.forename: Tonya C
authors.initials: TC
authors.lastname: Tromblee
authors.forename: Jeryl C
authors.initials: JC
authors.lastname: Jones
authors.forename: Ashley E
authors.initials: AE
authors.lastname: Etue
authors.forename: S Dru
authors.initials: SD
authors.lastname: Forrester
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000662:veterinary; D002371:Cat Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology; D002415:Cats; D004724:Endoscopy / Q000662:veterinary; D005260:Female; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000662:veterinary; D008297:Male; D008396:Maryland / Q000453:epidemiology; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000662:veterinary; D010254:Paranasal Sinus Diseases / Q000000981:diagnostic imaging / Q000662:veterinary*; D011237:Predictive Value of Tests; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000662:veterinary*; D014768:Virginia / Q000453:epidemiology