Narcolepsy-cataplexy associated with precocious puberty.
In children, narcolepsy may be the symptom of a brain lesion or genetic disease. The authors report two cases with severe narcolepsy-cataplexy emerging in childhood in close temporal association with obesity and precocious puberty.
Plazzi
G
G
Department of Neurological Sciences, University of Bologna, Italy. giuseppe.plazzi@unibo.it
Parmeggiani
A
A
Mignot
E
E
Lin
L
L
Scano
M C
MC
Posar
A
A
Bernardi
F
F
Lodi
R
R
Tonon
C
C
Barbiroli
B
B
Montagna
P
P
Cicognani
A
A
D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000032:analysis; D001559:Benzhydryl Compounds / Q000627:therapeutic use; D002385:Cataplexy / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D003401:Creatine / Q000032:analysis; D003511:Cyclohexanols / Q000627:therapeutic use; D006970:Disorders of Excessive Somnolence / Q000209:etiology; D005260:Female; D006212:Hallucinations / Q000209:etiology; D006266:Health Education; D006801:Humans; D007031:Hypothalamus / Q000737:chemistry / Q000503:physiopathology*; D047908:Intracellular Signaling Peptides and Proteins / Q000172:deficiency / Q000502:physiology*; D008297:Male; D000077408:Modafinil; D009290:Narcolepsy / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009479:Neuropeptides / Q000172:deficiency / Q000502:physiology*; D020184:Night Terrors / Q000209:etiology; D009765:Obesity / Q000150:complications; D000068797:Orexins; D017286:Polysomnography; D011629:Puberty, Precocious / Q000150:complications* / Q000503:physiopathology; D013690:Television; D000069470:Venlafaxine Hydrochloride
D001559:Benzhydryl Compounds; D003511:Cyclohexanols; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D000068797:Orexins; D001224:Aspartic Acid; D000069470:Venlafaxine Hydrochloride; C000179:N-acetylaspartate; D003401:Creatine; D000077408:Modafinil