Two-dimensional color tissue Doppler imaging detects myocardial dysfunction before occurrence of hypertrophy in a young Maine Coon cat.
A 20-month-old healthy male Maine Coon cat was referred for a cardiovascular evaluation. Physical examination and electrocardiogram were normal. The end-diastolic subaortic interventricular septal thickness (6 mm; reference range: < or = 6mm) and the mitral flow late diastolic velocity (0.89 m/s; reference range: 0.2-0.8m/s) were within the upper ranges. However, M-mode echocardiography did not reveal any sign of hypertrophic cardiomyopathy (HCM). Tissue Doppler imaging (TDI) identified a marked left ventricular free wall dysfunction characterized by decreased myocardial velocities in early diastole, increased myocardial velocities in late diastole and the presence of postsystolic contractions both at the base and the apex for the longitudinal motion. One year later, the diagnosis of HCM was confirmed by conventional echocardiography and the cat died suddenly 2 months later. This report demonstrates for the first time in spontaneous HCM the sensitivity of TDI for early diagnosis of myocardial dysfunction and suggests that TDI should form part of the screening techniques for early diagnosis of feline HCM.
Chetboul
Valerie
V
Cardiology Unit of Alfort National Veterinary School of Alfort, 7 Avenue du Général de Gaulle, 94 704 Maisons-Alfort Cedex, France. vchetboul@vet-alfort.fr
Sampedrano
Carolina Carlos
CC
Gouni
Vassiliki
V
Nicolle
Audrey P
AP
Pouchelon
Jean-Louis
JL
D000818:Animals; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000662:veterinary*; D002371:Cat Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002415:Cats; D003937:Diagnosis, Differential; D004452:Echocardiography / Q000662:veterinary; D008297:Male; D018615:Ultrasonography, Doppler, Color / Q000662:veterinary; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology / Q000662:veterinary*