title: Deep neck infection in elderly patients. A single institution experience (2000-2004).
abstract: OBJECTIVE
  Immunosenescence, the age-related decline in immunologic function in healthy individuals, seems to contribute to increased susceptibility to bacterial infections in the elderly population. The present study describes elderly patients' susceptibility to deep neck infection and prognosis.
  
  
  METHODS
  Between January 2000 and March 2004, 103 patients were admitted to the Department of Otolaryngology, University of Padova for deep neck infection. Twenty-four patients (23%) were over 65 (elderly patients). The remaining 79 patients (77%) aged < or =65 years (adult non-elderly patients) were also studied. Presentation modalities, origin of infection, site of deep neck infection, radiological investigations, bacteriology, treatment and outcome were all studied.
  
  
  RESULTS
  Hypertension and diabetes mellitus were the most commonly associated systemic diseases in both elderly and non-elderly patients. The number of patients with associated systemic diseases was significantly higher in the elderly group. The most common cause of deep neck infection was dental infection in both age groups. In the elderly group, salivary gland origin had the same incidence as dental origin. Twenty-two patients (6 elderly patients) were treated only with intravenous antibiotic therapy and intravenous steroids. Overall, in 81 cases (78.6%) (18 elderly patients) medical plus surgical procedures were indicated. None of the treated patients died of deep neck infection or its complications.
  
  
  CONCLUSIONS
  Although the incidence of associated systemic diseases and complications of deep neck infections were higher in the elderly group, our medical or medical plus surgical approaches to deep neck infections, based on clinical and radiological evidence, were successful in all patients treated.
authors.affiliation: Department of Medical and Surgical Specialties, Section of Otolaryngology, University of Padova, 35128 Padova, Italy. gino.marioni@unipd.it.
authors.forename: Gino
authors.initials: G
authors.lastname: Marioni
authors.forename: Eugenio
authors.initials: E
authors.lastname: Castegnaro
authors.forename: Claudia
authors.initials: C
authors.lastname: Staffieri
authors.forename: Roberto
authors.initials: R
authors.lastname: Rinaldi
authors.forename: Luciano
authors.initials: L
authors.lastname: Giacomelli
authors.forename: Marco
authors.initials: M
authors.lastname: Boninsegna
authors.forename: Andy
authors.initials: A
authors.lastname: Bertolin
authors.forename: Alberto
authors.initials: A
authors.lastname: Staffieri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000276:immunology / Q000473:pathology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology; D004198:Disease Susceptibility / Q000473:pathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D012189:Retrospective Studies; D012466:Salivary Gland Diseases / Q000150:complications / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D014076:Tooth Diseases / Q000150:complications / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents