FloDots: luminescent nanoparticles.
Luminescent dye-doped silica nanoparticles (FloDots) have been developed for ultrasensitive bioanalysis and diagnosis in the past several years. Those novel nanoparticles are highly luminescent and extremely photostable. In this paper, we review the preparation, characterization, bioconjugation and bioapplication of FloDots. All the results clearly demonstrated that FloDots have many advantages over currently used luminescent probes, such as traditional fluorophores and quantum dots.
Yao
Gang
G
Center for Research at the Bio/nano Interface, Department of Chemistry and Shands Cancer Center, University of Florida, Gainesville, FL 32611-7200, USA.
Wang
Lin
L
Wu
Yanrong
Y
Smith
Josh
J
Xu
Jinsheng
J
Zhao
Wenjun
W
Lee
Eunjung
E
Tan
Weihong
W
D006801:Humans; D049449:Luminescence; D046228:Microarray Analysis; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010777:Photochemistry