title: Phosphatidylinositol-transfer protein and its homologues in yeast.
abstract: Yeast Sec14p acts as a phosphatidylinositol/phosphatidylcholine-transfer protein in vitro. In vivo, it is essential in promoting Golgi secretory function. Products of five genes named SFH1-SFH5 (Sec Fourteen Homologues 1-5) exhibit significant sequence homology to Sec14p and together they form the Sec14p family of lipid-transfer proteins. It is a diverse group of proteins with distinct subcellular localizations and varied physiological functions related to lipid metabolism and membrane trafficking.
authors.affiliation: Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Ivanka pri Dunaji, Slovakia. Peter.Griac@savba.sk
authors.forename: P
authors.initials: P
authors.lastname: Griac
authors.forename: R
authors.initials: R
authors.lastname: Holic
authors.forename: D
authors.initials: D
authors.lastname: Tahotna
mesh_terms: D005810:Multigene Family; D010716:Phosphatidylinositols / Q000737:chemistry / Q000378:metabolism*; D049294:Phospholipid Transfer Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D017386:Sequence Homology, Amino Acid
chemical_list: D010716:Phosphatidylinositols; D049294:Phospholipid Transfer Proteins