title: [Safe management of anesthesia with total intravenous anesthesia using propofol, fentanyl and ketamine for a patient treated with intraoperative radiotherapy].
abstract: A 3-year-old girl with neuroblastoma was scheduled for intraoperative radiation therapy. Prior to surgery, meetings were held to ensure the safety during transfer between the operating room and the radiation unit because those units were placed on the different floors in our hospital. In the operating room the patient was anesthetized with propofol, fentanyl and ketamine (PFK). After the resection of the tumor, the patient was moved to the radiation unit. All personnel had to leave the treatment room while the radiation was administered, which required 3 minutes. During the transfer and treatment, the following apparatus were effective to ensure the patient's safety; mobile respiratory and cardiovascular monitors, closed-circuit television to observe the monitors and patient, and a portable gas powered ventilator. The total intravenous anesthesia with PFK was used throughout all scheduled procedures. For patients treated with intraoperative radiation therapy, the administration of inhalation anesthetics should be discontinued to supply 100% oxygen, which enhances the effect of irradiation, and to avoid the complexity of the transfer with an anesthetic machine. This discontinuation, however, may cause the cardiovascular instability. It seems that total intravenous anesthesia has advantages over inhalation anesthesia for patients who undergo intraoperative radiation therapy.
authors.affiliation: Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki 036-8562.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yoshida
authors.forename: Hitomi
authors.initials: H
authors.lastname: Nakamura
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ono
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kushikata
authors.forename: Hironori
authors.initials: H
authors.lastname: Ishihara
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Hirota
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D000771:Anesthesia, Intravenous / Q000379:methods*; D002675:Child, Preschool; D005260:Female; D005283:Fentanyl; D006801:Humans; D007430:Intraoperative Care; D007649:Ketamine; D008991:Monitoring, Physiologic; D015742:Propofol; D012121:Respiration, Artificial; D012449:Safety
chemical_list: D007649:Ketamine; D005283:Fentanyl; D015742:Propofol