Off-label reports of new biologics: exciting new therapy or dubious research? Examples from recombinant activated factor VII.
Dzik
Walter H
WH
Blood Tranfusion Service, Massachusetts General Hospital, Boston, 02114, USA. sdzik@partners.org
D001291:Attitude of Health Personnel; D001688:Biological Products / Q000627:therapeutic use*; D017277:Drug Approval / Q000331:legislation & jurisprudence; D004341:Drug Evaluation / Q000941:ethics / Q000379:methods; D004348:Drug Labeling; D015507:Drugs, Investigational / Q000627:therapeutic use*; D026690:Ethics, Clinical; D015942:Factor VIIa / Q000627:therapeutic use*; D006801:Humans; D009042:Motivation; D014481:United States
D001688:Biological Products; D015507:Drugs, Investigational; D015942:Factor VIIa