title: Late-onset eccrine angiomatous hamartoma on the forehead.
abstract: A 71-year-old Korean man presented with a solitary erythematous plaque on his forehead (Fig. 1). It was first noticed by the patient 1 year previously and had slowly increased in size over that time. Physical examination revealed a slightly elevated, 1.5 cm x 1.5 cm erythematous plaque on the upper midline of the forehead. Sweating was not evoked by physical work or emotional stress. There was no pain or tenderness associated with the lesion. The patient had no history of trauma to the forehead. Histopathologic examination of the lesion showed increased numbers of eccrine glands, as well as dilated vascular channels in the deep dermis and subcutaneous tissue (Fig. 2). An immunohistochemical study showed that these eccrine glands stained positively for S-100 and carcinoembryonic antigen (CEA), and the vascular channels for the antifactor VIII-related antigens. These findings are consistent with eccrine angiomatous hamartoma. There was no change in the lesion during the 1-year follow-up period.
authors.affiliation: Department of Dermatology, College of Medicine, Catholic University of Korea, St Mary's Hospital, Seoul, South Korea.
authors.forename: Eugene
authors.initials: E
authors.lastname: Jeong
authors.forename: Hyun Jeong
authors.initials: HJ
authors.lastname: Park
authors.forename: Sin Taik
authors.initials: ST
authors.lastname: Oh
authors.forename: Jun Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Baik Kee
authors.initials: BK
authors.lastname: Cho
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005546:Forehead / Q000473:pathology; D006222:Hamartoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D013543:Sweat Gland Diseases / Q000175:diagnosis* / Q000473:pathology