title: Acanthamoeba encephalitis in patient with systemic lupus, India.
abstract: We report a fatal case of encephalitis caused by Acanthamoeba in a 24-year-old woman from India with systemic lupus erythematosus. Diagnosis was made by identification of amebas in brain sections by immunofluorescence analysis and confirmed by demonstrating Acanthamoeba mitochondrial 16S rRNA gene DNA in brain tissue sections.
authors.affiliation: P.D. Hinduja National Hospital and Research Centre, Mumbai, India.
authors.forename: Charudatt G
authors.initials: CG
authors.lastname: Shirwadkar
authors.forename: Rohini
authors.initials: R
authors.lastname: Samant
authors.forename: Milind
authors.initials: M
authors.lastname: Sankhe
authors.forename: Ramesh
authors.initials: R
authors.lastname: Deshpande
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yagi
authors.forename: Frederick L
authors.initials: FL
authors.lastname: Schuster
authors.forename: Rama
authors.initials: R
authors.lastname: Sriram
authors.forename: Govinda S
authors.initials: GS
authors.lastname: Visvesvara
mesh_terms: D000048:Acanthamoeba / Q000235:genetics / Q000254:growth & development*; D000328:Adult; D000562:Amebiasis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D000818:Animals; D020808:Central Nervous System Protozoal Infections / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D004660:Encephalitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007194:India; D008180:Lupus Erythematosus, Systemic / Q000469:parasitology*; D016133:Polymerase Chain Reaction
chemical_list: D016054:DNA, Protozoan