title: Embryo quality is more important for younger women whereas age is more important for older women with regard to in vitro fertilization outcome and multiple pregnancy.
abstract: OBJECTIVE
  To determine the efficiency of embryo scoring systems for multiple pregnancy in women undergoing IVF procedures.
  
  
  METHODS
  Retrospective record analysis.
  
  
  METHODS
  University hospital, tertiary medical center.
  
  
  METHODS
  Three hundred one patients undergoing controlled ovarian stimulation, IVF/intracytoplasmic sperm injection (ICSI), and day 3 embryo transfer.
  
  
  METHODS
  IVF/ICSI and embryo transfer.
  
  
  METHODS
  Rate of pregnancy and rate of multiple pregnancy.
  
  
  RESULTS
  The score of the best three embryos (Top3) was more correlated with IVF outcome than were the number of good embryos (P=.009) or the cumulative embryo score (P=.038). In the logistic regression model, Top3 was more relevant to IVF outcome and multiple pregnancy for younger patients than was age (P<.05). For older patients, age was more correlated with IVF outcome and multiple pregnancy than was embryo morphology (P<.05).
  
  
  CONCLUSIONS
  The embryo morphology criteria can help reduce the number of embryos transferred into younger patients. We could use the age of patients as an indicator to determine the number of embryos transferred into older patients.
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Lee
authors.forename: Chin-Der
authors.initials: CD
authors.lastname: Chen
authors.forename: Yi-Yi
authors.initials: YY
authors.lastname: Tsai
authors.forename: Li-Jung
authors.initials: LJ
authors.lastname: Chang
authors.forename: Hong-Nerng
authors.initials: HN
authors.lastname: Ho
authors.forename: Yu-Shih
authors.initials: YS
authors.lastname: Yang
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D004624:Embryo Transfer / Q000706:statistics & numerical data*; D004622:Embryo, Mammalian / Q000033:anatomy & histology*; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology* / Q000628:therapy*; D017063:Outcome Assessment, Health Care / Q000379:methods; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology; D016896:Treatment Outcome