title: Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
abstract: A 20-year-old man was admitted to our hospital for treatment of verapamil sensitive idiopathic left ventricular tachycardia (ILVT). During the electrophysiologic study (EPS), no sustained ventricular tachycardia (VT) could be induced both at baseline and after infusion of isoproterenol. However, sustained clinical VT could be easily induced with single ventricular extrastimulation following intravenous administration of pilsicainide, a class Ic sodium channel blocker. The arrhythmia was ablated with radiofrequency catheter ablation.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nagai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Suyama
authors.forename: Wataru
authors.initials: W
authors.lastname: Shimizu
authors.forename: Takashi
authors.initials: T
authors.lastname: Noda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Satomi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kurita
authors.forename: Naohiko
authors.initials: N
authors.lastname: Aihara
authors.forename: Shiro
authors.initials: S
authors.lastname: Kamakura
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents; D004338:Drug Combinations; D004562:Electrocardiography; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives*; D008297:Male; D017180:Tachycardia, Ventricular / Q000150:complications / Q000175:diagnosis*; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis*; D014700:Verapamil
chemical_list: D000889:Anti-Arrhythmia Agents; D004338:Drug Combinations; D008012:Lidocaine; C042288:pilsicainide; D014700:Verapamil