title: High resolution micro-CT scanning as an innovative tool for evaluation of the surgical positioning of cochlear implant electrodes.
abstract: X-ray microtomography (micro-CT) is a new technique allowing for visualization of the internal structure of opaque specimens with a quasi-histological quality. Among multiple potential applications, the use of this technique in otology is very promising. Micro-CT appears to be ideally suited for in vitro visualization of the inner ear tissues as well as for evaluation of the electrode damage and/or surgical insertion trauma during implantation of the cochlear implant electrodes. This technique can greatly aid in design and development of new cochlear implant electrodes and is applicable for temporal bone studies. The main advantage of micro-CT is the practically artefact-free preparation of the samples and the possibility of evaluation of the interesting parameters along the whole insertion depth of the electrode. This paper presents the results of the first application of micro-CT for visualization of the inner ear structures in human temporal bones and for evaluation of the surgical positioning of the cochlear implant electrodes relative to the intracochlear soft tissues.
authors.affiliation: Department of Physics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. andrei.postnov@ua.ac.be
authors.forename: A
authors.initials: A
authors.lastname: Postnov
authors.forename: A
authors.initials: A
authors.lastname: Zarowski
authors.forename: N
authors.initials: N
authors.lastname: De Clerck
authors.forename: F
authors.initials: F
authors.lastname: Vanpoucke
authors.forename: F E
authors.initials: FE
authors.lastname: Offeciers
authors.forename: D
authors.initials: D
authors.lastname: Van Dyck
authors.forename: S
authors.initials: S
authors.lastname: Peeters
mesh_terms: D016477:Artifacts; D003051:Cochlea / Q000000981:diagnostic imaging / Q000473:pathology; D019929:Cochlear Implantation / Q000295:instrumentation*; D004567:Electrodes, Implanted; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D021621:Imaging, Three-Dimensional / Q000295:instrumentation*; D008866:Microsurgery / Q000295:instrumentation*; D012533:Scala Tympani / Q000000981:diagnostic imaging / Q000473:pathology; D012680:Sensitivity and Specificity; D012984:Software; D013382:Subtraction Technique / Q000295:instrumentation; D025321:Surgery, Computer-Assisted / Q000295:instrumentation*; D013673:Technology Assessment, Biomedical; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000601:surgery; D036542:Tomography, Spiral Computed / Q000295:instrumentation*