title: [Diagnosis and treatment of Zollinger-Ellison syndrome].
abstract: In 1970-2005 yrs. 65 patients with Zollinger-Ellison syndrome were observed and operated on in the clinic. The decisive meaning in diagnosis owes radioimmunological determination of gastrin level in the blood and its changes while conduction of tests with calcium and secretin. Surgical tactics was determined by localization, number and character of gastrinomas. During the first period of work gastrectomy with complete excision of gastrinproducing tumor constituted the operation of choice. Implementation of intraoperative method of ultrasonography have permitted to excise the benign gastrinoma when her localization was favourable with preservation of stomach. Minimal life span after gastrectomy, performed for nonresectable malignant gastrinoma, have constituted 9 years.
authors.forename: V F
authors.initials: VF
authors.lastname: Saenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Dibrova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005743:Gastrectomy / Q000379:methods; D005755:Gastrins / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D016896:Treatment Outcome; D014463:Ultrasonography; D020535:Video-Assisted Surgery; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D005755:Gastrins