title: Neuromyelitis optica diagnosis in clinically isolated syndromes suggestive of multiple sclerosis.
abstract: The authors assessed the extent of overlap between current diagnostic criteria of neuromyelitis optica (NMO) and multiple sclerosis (MS) by applying NMO criteria to a large cohort of 320 patients with clinically isolated syndromes (CIS). Twenty-three (7.2%) patients fulfilled NMO absolute criteria at some time and 1 (0.3%) also fulfilled one major supportive criterion. Therefore, even by systematically applying NMO criteria in patients with CIS, NMO diagnosis is reached infrequently.
authors.affiliation: Unitat de Neuroinmunologia Clínica, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Rubiera
authors.forename: J
authors.initials: J
authors.lastname: Río
authors.forename: M
authors.initials: M
authors.lastname: Tintoré
authors.forename: C
authors.initials: C
authors.lastname: Nos
authors.forename: A
authors.initials: A
authors.lastname: Rovira
authors.forename: N
authors.initials: N
authors.lastname: Téllez
authors.forename: X
authors.initials: X
authors.lastname: Montalban
mesh_terms: D000328:Adult; D000465:Algorithms; D001921:Brain / Q000473:pathology; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis*; D009187:Myelitis / Q000209:etiology*; D009471:Neuromyelitis Optica / Q000150:complications / Q000175:diagnosis*; D009900:Optic Nerve / Q000473:pathology; D009902:Optic Neuritis / Q000209:etiology*; D012008:Recurrence; D016037:Single-Blind Method; D013116:Spinal Cord / Q000473:pathology