Synthesis of electron deficient 5,6-aryloxy spiroketals.
[reaction: see text] A strategy for the construction of electron deficient 5,6-aryloxy spiroketal is reported. The process should prove useful for the synthesis of natural products containing similar spiroketals. The strategy uncovers an unexpected rearrangement between ortho and para quinone spiroketals.
Lindsey
Christopher C
CC
Department of Chemistry and Biochemistry, University of California at Santa Barbara, 93106-9510, USA.
Wu
Kun Liang
KL
Pettus
Thomas R R
TR
D015394:Molecular Structure; D010084:Oxidation-Reduction; D011809:Quinones / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D011809:Quinones; D013141:Spiro Compounds; C064947:beta-rubromycin