Borrelia burgdorferi--traveling incognito?
We outline in this review how Borrelia burgdorferi, the causative agent of Lyme disease, moves from the tick to the vertebrate host, and what molecules are potentially involved in this challenging commute. The survival strategies utilized by the spirochete during transmission and the initial stages of infection are discussed.
Fikrig
Erol
E
Section of Rheumatology, Department of Medicine, Yale University School of Medicine, Room 525A, 300 Cedar Street, New Haven, CT 06520-8031, USA. erol.fikrig@yale.edu
Narasimhan
Sukanya
S
D000818:Animals; D001096:Arachnid Vectors / Q000382:microbiology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D025065:Borrelia burgdorferi / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D018884:Ixodes / Q000382:microbiology*; D008193:Lyme Disease / Q000276:immunology / Q000382:microbiology* / Q000635:transmission*
D001426:Bacterial Proteins