title: Malignant hidradenoma of the medial canthus with orbital and intracranial extension.
abstract: A 70-year-old woman presented with signs and symptoms consistent with nasolacrimal duct obstruction. MRI revealed a medial canthal mass with orbital and intracranial extension. The patient was treated with wide surgical excision, chemotherapy, and radiation. A diagnosis of malignant hidradenoma of the medial canthus was confirmed by histopathology. Despite aggressive therapy, the patient developed metastatic disease and died within 1 year.
authors.affiliation: Rocky Mountain Lions Eye Institute, Aurora, CO 80045, USA. vikram.durairaj@uchsc.edu
authors.forename: Vikram D
authors.initials: VD
authors.lastname: Durairaj
authors.forename: Heather M
authors.initials: HM
authors.lastname: Bartlett
authors.forename: Sherif
authors.initials: S
authors.lastname: Said
mesh_terms: D006607:Adenoma, Sweat Gland / Q000473:pathology* / Q000628:therapy; D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003399:Craniotomy; D005004:Ethmoid Bone / Q000601:surgery; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009918:Orbital Neoplasms / Q000556:secondary* / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000556:secondary* / Q000628:therapy; D018714:Radiotherapy, Adjuvant