title: Peculiarities of lipid profile parameters in cardiac patients with hypo- and hyperthyroidism.
abstract: The problem of thyroid dysfunction is very actual in cardiac patients. The aim of the present study was to evaluate lipid profile parameters in 73 hypo-, hyper- and euthyroid cardiology patients visited the Emergency Cardiology Center. Most of the patients had coronary artery disease. Thyroid dysfunction was diagnosed on the basis of patients' clinical status and blood thyroid stimulating hormone. In hypothyroid patients blood levels of total cholesterol, low-density lipoprotein cholesterol and triglycerides were increased. In contrast, the patients with hyperthyroidism had normal concentrations of these parameters. Exception was antiatherogenic fraction of lipid profile - high-density lipoprotein cholesterol, which mean levels were normal in all patients' groups. It is noteworthy that the highest levels of atherogenic fractions were observed in the groups of patients who had hypothyroidism in combination with diabetes mellitus. In conclusion, the results of present study showed that thyroid dysfunction may play a potential independent role in changes of atherogenic lipid profile.
authors.affiliation: Emergency Cardiology Center, Tbilisi, Georgia.
authors.forename: G
authors.initials: G
authors.lastname: Chapidze
authors.forename: N
authors.initials: N
authors.lastname: Dolidze
authors.forename: M
authors.initials: M
authors.lastname: Williams
authors.forename: E
authors.initials: E
authors.lastname: Sharadze
authors.forename: N
authors.initials: N
authors.lastname: Latsabidze
mesh_terms: D002784:Cholesterol / Q000097:blood*; D003324:Coronary Artery Disease / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000453:epidemiology / Q000378:metabolism / Q000503:physiopathology; D007037:Hypothyroidism / Q000453:epidemiology / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides; D002784:Cholesterol