Prenatal therapy for fetal growth restriction.
The choice of therapy for fetal growth restriction (FGR) depends on the nature of the insult that led to the development of FGR. Many etiologic factors are either not amenable to therapy or fetal growth has not been improved by treatments that benefit the mother. Many therapeutic approaches have been used to improve fetal condition. None of the approaches have been of value in a consistent manner. We present the numerous approaches, and their rationale for their use, that have been tried to treat the growth impaired fetus. The evidence from the randomized clinical trials is summarized and their conclusions given.
Figueroa
Reinaldo
R
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Winthrop University Hospital, Mineola, New York, USA. rfigueroa@notes.cc.sunysb.edu
Maulik
Dev
D
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage; D001510:Bed Rest; D002121:Calcium Channel Blockers / Q000008:administration & dosage; D002136:Calcium, Dietary / Q000008:administration & dosage; D004039:Diet, Sodium-Restricted; D019587:Dietary Supplements; D005260:Female; D005317:Fetal Growth Retardation / Q000188:drug therapy / Q000517:prevention & control / Q000628:therapy*; D005395:Fish Oils / Q000008:administration & dosage; D005492:Folic Acid / Q000008:administration & dosage; D006801:Humans; D058085:Iron Compounds / Q000008:administration & dosage; D008150:Lower Body Negative Pressure; D017616:Magnesium Compounds / Q000008:administration & dosage; D015201:Meta-Analysis as Topic; D020030:Nitric Oxide Donors / Q000008:administration & dosage; D018529:Nutritional Support; D010102:Oxygen Inhalation Therapy; D010952:Plasma Substitutes / Q000008:administration & dosage; D011247:Pregnancy; D011256:Pregnancy Outcome; D016032:Randomized Controlled Trials as Topic; D014815:Vitamins / Q000008:administration & dosage; D017967:Zinc Compounds / Q000008:administration & dosage
D000318:Adrenergic beta-Agonists; D002121:Calcium Channel Blockers; D002136:Calcium, Dietary; D005395:Fish Oils; D058085:Iron Compounds; D017616:Magnesium Compounds; D020030:Nitric Oxide Donors; D010952:Plasma Substitutes; D014815:Vitamins; D017967:Zinc Compounds; D005492:Folic Acid; D001241:Aspirin