[Effect of exogenous DNA on the growth of transplantable tumors].
Using transplantable Ehrlich ascites tumor, hepatoma HA-1 and Lewis carcinoma it was shown, that preparations of fragmented genomic DNA can more or less effectively inhibit such tumors as well as the growth of their metastases. Such effects were produced by DNA preparations derived from tissues of mice, both syngeneic or allogeneic to tumor-bearer, as well as from human tissues.
Nikolin
V P
VP
Popova
N A
NA
Sebeleva
T E
TE
Strunkin
D N
DN
Rogachev
V A
VA
Semënov
D V
DV
Bogachev
S S
SS
Iakubov
L A
LA
Shurdov
M A
MA
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D018827:Carcinoma, Lewis Lung / Q000188:drug therapy*; D004247:DNA / Q000494:pharmacology* / Q000627:therapeutic use; D053938:DNA Fragmentation; D006801:Humans; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008813:Mice, Inbred ICR; D009368:Neoplasm Transplantation
D004247:DNA