[Human cytogenetics. From 1956 to 2006].
The correct enumeration of human chromosomes, only established in 1956, has marked the starting point of the modern cytogenetics. The introduction of banding techniques, then of in situ hybridization techniques, and now of genomic microarray technology allowed a dramatic development of cytogenetics of which the main applications to basic and medical research are evoked in this review.
Berger
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Hôpital Necker-Enfants-Malades, EMI 0210 Inserm, 149, rue de Sèvres, 75743 Paris cedex 15, France. berger@necker.fr
D002471:Cell Transformation, Neoplastic / Q000235:genetics; D043171:Chromosomal Instability; D025063:Chromosome Disorders / Q000235:genetics; D043283:Chromosome Fragile Sites; D020732:Cytogenetic Analysis; D003582:Cytogenetics / Q000639:trends*; D005544:Forecasting; D052138:Genes, Neoplasm; D006801:Humans; D007621:Karyotyping; D016296:Mutagenesis; D009369:Neoplasms / Q000235:genetics