title: First trimester medical termination of pregnancy: an alternative for New Zealand women.
abstract: BACKGROUND
  First trimester medical terminations of pregnancy (TOP) have been carried out in a private abortion clinic in Auckland from 1 July 2003 to 30 June 2005.
  
  
  OBJECTIVE
  To audit first trimester medical TOP outcomes over the first 2 years and to compare the demographics and complication rates of women opting for medical TOP with those choosing surgical TOP during this period.
  
  
  METHODS
  Retrospective, consecutive case audit of women presenting for a first trimester TOP. Anonymous audit included ethnicity, gestation at first appointment, pain relief requirements, blood loss, timing from the taking of misoprostol to expulsion of products of conception, complications and comparison of outcomes and characteristics between medical termination of pregnancy (MTOP) and surgical termination of pregnancy (STOP).
  
  
  RESULTS
  A total of 3311 TOPs were performed over the 2-year study period, including 390 MTOPs (12%). No significant differences were found in age, ethnicity or history of previous TOP between women choosing MTOP or STOP. Gravida 1 and nulliparous women were significantly more likely to choose MTOP. Five per cent (21/390) of women taking mifepristone progressed to STOP. Complications involving hospitalisation occurred in six MTOPs (1.5%) and 18 STOPs (0.6%).
  
  
  CONCLUSIONS
  First trimester MTOP is safe and effective and is a realistic alternative for women wanting choice of method in New Zealand.
authors.affiliation: Auckland Medical Aid Centre, Mt. Eden, Auckland, New Zealand. f.goodyear-smith@auckland.ac.nz
authors.forename: Felicity
authors.initials: F
authors.lastname: Goodyear-Smith
authors.forename: Alison
authors.initials: A
authors.lastname: Knowles
authors.forename: Jonathan
authors.initials: J
authors.lastname: Masters
mesh_terms: D000019:Abortifacient Agents / Q000008:administration & dosage; D000028:Abortion, Induced / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D000293:Adolescent; D000328:Adult; D000554:Ambulatory Care Facilities / Q000592:standards; D002648:Child; D005260:Female; D006801:Humans; D008485:Medical Audit; D008499:Medical Records; D015735:Mifepristone / Q000008:administration & dosage; D009520:New Zealand / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012189:Retrospective Studies
chemical_list: D000019:Abortifacient Agents; D015735:Mifepristone