Proteome chips for whole-organism assays.
Over the past 5 years, protein-chip technology has emerged as a useful tool for the study of many kinds of protein interactions and biochemical activities. The construction of Saccharomyces cerevisiae whole-proteome arrays has enabled further studies of such interactions in a proteome-wide context. Here, we explore some of the recent advances that have been made at the '-omic' level using protein microarrays.
Kung
Li A
LA
Department of Molecular, Cellular and Developmental Biology, Yale University, 266 Whitney Avenue, New Haven, Connecticut 06511, USA. li.kung@yale.edu
Snyder
Michael
M
D000818:Animals; D001709:Biotechnology; D020869:Gene Expression Profiling; D006801:Humans; D040081:Protein Array Analysis / Q000295:instrumentation / Q000379:methods; D020543:Proteome / Q000032:analysis*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism
D020543:Proteome; D029701:Saccharomyces cerevisiae Proteins