[Non-alkaloid constituents from a Tibetan medicine Meconopsis quintuplinervia].
OBJECTIVE
To study the chemical constituents of a Tibetan medicine Meconopsis quintuplinervia.


METHODS
Column chromatographic techniques were applied to isolate constituents. A combination of IR, MS and NMR spectroscopy was used to identify structures of constituents.


RESULTS
Twelve compounds were isolated from the ethanolic extract and their structures were elucidated as quercetin 3-O-beta-D-glucopyranoside (I), quercetin 3-O-beta-D-galactopyranosyl-(1-->6)-glucopyranoside (II), kaempferol 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (III), isorhamnetin 3-0-beta-D-galactopyranosyl-(1-->6)-beta-D-glucopyranoside (IV), caffeic acid (V), protocatechuic acid (VI), p-hydroxycinnamic (VII), 2-(3,4-dihydroxyphenyl )-ethyl-O-beta-D-glucopyranoside (VIII), p-hydroxybenzoyl-beta-D-glucopyranoside (IX), 4-O-beta-D-glucopyranosyl-(Z)-p-coumaric acid (X), 5, 7-dihydroxy-4H-4-chromenone (XI), daucosterol (XII).


CONCLUSIONS
Ten compounds were isolated from this genus for the first time except for XI and XII.
Shang
Xiao-Ya
XY
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Be'iing 100050, China.
Li
Chong
C
Zhang
Cheng-Zhong
CZ
Yang
Yong-Chun
YC
Shi
Jian-Gong
JG
D002109:Caffeic Acids / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification*; D028101:Papaveraceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
D002109:Caffeic Acids; D005960:Glucosides; D062385:Hydroxybenzoates; C009091:protocatechuic acid; D011794:Quercetin; C110309:quercetin 3-O-glucopyranoside; C040048:caffeic acid