Labdane Diterpenoids from Marrubium globosum ssp. libanoticum.
From the aerial parts of Marrubium globosum ssp. libanoticum, seven labdane diterpenoids were isolated. Three of them are new natural products [(13R)-9alpha,13alpha-epoxylabda-6beta(19),16(15)-diol dilactone (2), deacetylvitexilactone (7), marrulanic acid (8)], whereas the other four, namely, (13S)-9alpha,13alpha-epoxylabda-6beta(19),16(15)-diol dilactone (1), cyllenin A (3), 15-epi-cyllenin A (4), and marrulibanoside, are previously known compounds. The structures of 2, 7, and 8 were determined by spectroscopic and chemical methods.
Rigano
Daniela
D
Department of Chemistry of Natural Products, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy.
Grassia
Armando
A
Bruno
Maurizio
M
Rosselli
Sergio
S
Piozzi
Franco
F
Formisano
Carmen
C
Arnold
Nelly Apostolides
NA
Senatore
Felice
F
D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D007861:Lebanon; D027522:Marrubium / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*
D004224:Diterpenes; C433017:labdane