"Cleaning" of nanoparticle inhibitors via proteolysis of adsorbed proteins.
Cytochrome c adsorbed to anionic nanoparticles is selectively proteolyzed by trypsin, providing a mechanism for the catalytic degradation of proteins.
Worrall
Joseph W E
JW
Department of Chemistry, University of Massachusetts at Amherst, Amherst, MA 01003, USA.
Verma
Ayush
A
Yan
Haoheng
H
Rotello
Vincent M
VM
D000327:Adsorption; D001665:Binding Sites; D002384:Catalysis; D045304:Cytochromes c / Q000737:chemistry*; D004587:Electrophoresis, Agar Gel / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013997:Time Factors; D014357:Trypsin / Q000737:chemistry*
D045304:Cytochromes c; D014357:Trypsin