[Depression of serum esterase and lipoprotein lipase activities in acute and longitudinal actions of ethanol].
Esterase (LCAT) and lipoprotein lipase (LPL) activities of blood serum, and a range of blood serum lipoproteins (LP) in acute and chronic ethanol intoxication were examined in healthy persons and patients with alcohol abuse. Ethanol inhibited LCAT and LPL activities, and increased apoA-containing LP in blood serum. These changes are considered as a basis for depression of a direct and reverse transportation of cholesterol in blood circulation under the action of ethanol.
Sokolik
V V
VV
Chursina
V S
VS
Artemchuk
A A
AA
Artemchuk
A F
AF
Bozhko
G Kh
GKh
D000328:Adult; D000435:Alcoholic Intoxication / Q000378:metabolism; D000437:Alcoholism / Q000378:metabolism*; D001054:Apolipoproteins A / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects; D008071:Lipoprotein Lipase / Q000037:antagonists & inhibitors* / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000037:antagonists & inhibitors / Q000097:blood / Q000378:metabolism*
D001054:Apolipoproteins A; D008074:Lipoproteins; D000431:Ethanol; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase; D008071:Lipoprotein Lipase