title: [Biological and clinical aspects of in vitro fertilization].
abstract: Roughly 15% of the French population is concerned by a problem of unfertility. Assisted reproductive technique may be proposed as a way to answer to this problem. In an IVF laboratory, several procedures may be carried out to obtain embryos in vitro, including micromanipulation as intracytoplasmic sperm injection. Among a high number of embryos obtained, only few will be selected for embryo transfer. The aim of this activity is to define which embryo present the best characteristics to undergone a positive implantation. Several criteria have been identified and positively correlated with pregnancy rates, however these criteria are not absolute. Finally, the medical team is often pressed to propose a double or a triple embryos transfer, in order to maintain an acceptable pregnancy rate but exhibiting the couple to a risk of multiple pregnancy.
authors.affiliation: Service d'histologie, embryologie, cytogénétique à orientation en biologie et génétique de la reproduction, hôpital Antoine Béclère, Clamart. nelly.frydman@abc.aphp.fr
authors.forename: Nelly
authors.initials: N
authors.lastname: Frydman
authors.forename: Laetitia
authors.initials: L
authors.lastname: Hesters
authors.forename: Rénato
authors.initials: R
authors.lastname: Fanchin
mesh_terms: D046149:Embryo Culture Techniques; D005306:Fertilization / Q000502:physiology; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans