title: [Renal cell renal carcinoma. Analysis of incidence and survival in a 90.000 citizens healthcare area].
abstract: OBJECTIVE
  To evaluate the most relevant epidemiological and survival data of the renal cell carcinoma (RCC) in a 90.000 citizens geographic area, as well as its association with risk factors such as tobacco or diuretic drugs use.
  
  
  METHODS
  All patients with the pathologic diagnosis of renal cell carcinoma between January 1st 1987 and January 31st 2004 were included in the study. Adjusted incidence rates (standardized) per 100.000 inhabitants year, annual percentage increase, and epidemic index in the health-care area VIII in Ciudad Real (90.000 inhabitants) were calculated. For the population adjustment we used the data Published by the National Institute of Statistics. We evaluated the differences in mortality between males/females, as well as in relation to tobacco consumption, using the chi-square test or the Fisher exact test, and the overall survival by a Cox regression model.
  
  
  RESULTS
  Thirty-eight RCC were diagnosed, with a maximum incidence of 7.21 cases per 100.000 inhabitants year. There was an annual percentage increase of 2.06% over the whole period. There were no statistically significant differences in gender-associated mortality (p = 0.1), tumor stage (p = 0.063), tobacco consumption (p = 0.13), diuretic drugs consumption (p = 0.69), or both (p = 0.5). Mortality was significantly higher during the first 5 years after surgery.
  
  
  CONCLUSIONS
  The incidence of RCC is progressively increasing, and it is predictable that this trend will be maintained in the next years. Overall mortality (any cause) associated with RCC is higher in the first five years after diagnosis.
authors.affiliation: Servicio de Urología, Hospital Santa Bárbara, Puertollano, Ciudad Real, España. danielsantosarrontes@yahoo.es
authors.forename: Daniel
authors.initials: D
authors.lastname: Santos Arrontes
authors.forename: Fernando
authors.initials: F
authors.lastname: de Castro Barbosa
authors.forename: María Paz
authors.initials: MP
authors.lastname: Valer López-Fando
authors.forename: Manuel
authors.initials: M
authors.lastname: Fernández Arjona
authors.forename: Ignacio
authors.initials: I
authors.lastname: Cortés Aránguez
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology*; D002391:Catchment Area, Health; D005260:Female; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000453:epidemiology*; D008297:Male; D012189:Retrospective Studies; D015996:Survival Rate