Myelin biogenesis: sorting out protein trafficking.
Myelin biogenesis is a complex process involving coordinated exocytosis, endocytosis, mRNA transport and cytoskeletal dynamics. Recent studies indicate that soluble neuronal signals may control the surface expression of proteolipid protein, a process that involves reduced endocytosis and/or increased transport carrier recruitment from an intracellular pool.
Anitei
Mihaela
M
Department of Neuroscience, University of Connecticut Medical School, Farmington, Connecticut 06030, USA.
Pfeiffer
Steven E
SE
D004705:Endocytosis; D011992:Endosomes / Q000502:physiology; D005089:Exocytosis; D008954:Models, Biological; D018991:Myelin Proteolipid Protein / Q000378:metabolism*; D009186:Myelin Sheath / Q000378:metabolism*; D021381:Protein Transport; D015398:Signal Transduction
D018991:Myelin Proteolipid Protein