title: Hemophagocytic syndrome and acute liver failure associated with ethylene glycol ingestion: a case report.
abstract: The authors describe a case of accidental ethylene glycol poisoning in an 18-month-old boy who developed hemophagocytic syndrome (HPS). Ethylene glycol is a common substance in various antifreeze preparations. Acute ethylene glycol intoxication is a medical emergency that, if not diagnosed correctly and treated aggressively, will lead to serious neurological, cardiopulmonary, and renal dysfunction, and may result in death. The taking of a detailed history, physical examination, and laboratory testing are essential for diagnosis. To the best of the authors' knowledge this is the first case in the literature of a subject who developed HPS after ethylene glycol intoxication.
authors.affiliation: Hacettepe University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Hematology, Sihhiye Ankara, Turkey. bkuskon@yahoo.com
authors.forename: Baris
authors.initials: B
authors.lastname: Kuskonmaz
authors.forename: Ali
authors.initials: A
authors.lastname: Duzova
authors.forename: Nuray Oksuz
authors.initials: NO
authors.lastname: Kanbur
authors.forename: Figen
authors.initials: F
authors.lastname: Gurakan
authors.forename: Fatma
authors.initials: F
authors.lastname: Gumruk
authors.forename: Aytemiz
authors.initials: A
authors.lastname: Gurgey
mesh_terms: D001856:Bone Marrow Examination; D019855:Ethylene Glycol / Q000506:poisoning*; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D017114:Liver Failure, Acute / Q000139:chemically induced; D051359:Lymphohistiocytosis, Hemophagocytic / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D011041:Poisoning
chemical_list: D019855:Ethylene Glycol