title: The effects of EDTA-Tris infusion on the equine endometrium.
abstract: Four groups of five pony mares each were used to determine if the intrauterine infusion of EDTA-Tris solution caused adverse effects on the endometrium. The uteri of mares were infused with either saline or EDTA-Tris solution or biopsied or sham-biopsied without infusion. Acute endometritis developed in one (20%) to three (60%) mares in each group during the seven days following treatment, but there were no differences (P > 0.05) in the incidence of endometritis among the groups. Endometrial fibrosis was not evident in biopsies taken on days 14, 30 and 60 following infusion of saline or EDTA-Tris. It was concluded that the endometrial response to saline and EDTA-Tris was not different and that EDTA-Tris may be a useful adjunct to treatment of uterine infections in the mare.
authors.affiliation: Department of Veterinary Medicine and Surgery College of Veterinary Medicine University of Missouri-Columbia Columbia, MO 65211 USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Youngquist
authors.forename: T L
authors.initials: TL
authors.lastname: Blanchard
authors.forename: D
authors.initials: D
authors.lastname: Lapin
authors.forename: W
authors.initials: W
authors.lastname: Klein