Insecticidal activity of synthetic amides on Spodoptera frugiperda.
The phytochemistry of the genus Piper (Piperaceae) has been widely studied due to the biological properties of amides from these plants. In this work, we have synthesized and evaluated the toxic effect of 11 amides against the fall armyworm Spodoptera frugiperda larvae. The naturally occurring piperine was also evaluated. The most active amide was N-[3-(3',4'-methylenedioxyphenyl)-2-(E)-propenoyl]piperidine with a LD50 of 1.07 microg mg(-1) larvae. This amide was also evaluated by ingestion.
Batista-Pereira
Luciane G
LG
Departamento de Química, Universidade Federal de São Carlos, Brazil.
Castral
Thais C
TC
da Silva
Marina T M
MT
Amaral
Bruna R
BR
Fernandes
João B
JB
Vieira
Paulo C
PC
da Silva
M Fatima G F
MF
Corrêa
Arlene G
AG
D000577:Amides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007814:Larva / Q000187:drug effects / Q000254:growth & development*; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification; D011679:Pupa / Q000187:drug effects; D018411:Spodoptera / Q000187:drug effects / Q000254:growth & development*
D000577:Amides; D007306:Insecticides; D010880:Piperidines