Advanced analysis of metal distributions in human hair.
A variety of techniques (secondary electron microscopy with energy dispersive X-ray analysis, time-of-flight--secondary ion mass spectrometry, and synchrotron X-ray fluorescence) were utilized to distinguish metal contamination occurring in hair arising from endogenous uptake from an individual exposed to a polluted environment, in this case a lead smelter. Evidence was sought for elements less affected by contamination and potentially indicative of biogenic activity. The unique combination of surface sensitivity, spatial resolution, and detection limits used here has provided new insight regarding hair analysis. Metals such as Ca, Fe, and Pb appeared to have little representative value of endogenous uptake and were mainly due to contamination. Cu and Zn, however, demonstrate behaviors worthy of further investigation into relating hair concentrations to endogenous function.
Kempson
Ivan M
IM
Ian Wark Research Institute, University of South Australia, Mawson Lakes, S.A., 5095, Australia. Ivan.Kempson@unisa.edu.au
Skinner
William M
WM
Kirkbride
K Paul
KP
D002118:Calcium / Q000032:analysis; D003300:Copper / Q000032:analysis; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis*; D019015:Geologic Sediments / Q000737:chemistry*; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007501:Iron / Q000032:analysis; D007854:Lead / Q000032:analysis; D008670:Metals / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D013052:Spectrometry, X-Ray Emission; D015032:Zinc / Q000032:analysis
D004785:Environmental Pollutants; D008670:Metals; D007854:Lead; D003300:Copper; D007501:Iron; D015032:Zinc; D002118:Calcium