title: Allylcyanation of alkynes: regio- and stereoselective access to functionalized di- or trisubstituted acrylonitriles.
abstract: Allyl cyanides are found to add across alkynes in the presence of a nickel catalyst prepared from Ni(cod)2 and P(4-CF3-C6H4)3 in situ to give variously functionalized di- or trisubstituted acrylonitriles in highly stereoselective manners possibly via a pi-allylnickel species as an intermediate. alpha-Siloxyallyl cyanides also react at the gamma-position of a cyano group with both internal and terminal alkynes having various functional groups to give silyl enol ethers, which give the corresponding aldehydes or ketones upon hydrolysis.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. nakao@npc05.kuic.kyoto-u.ac.jp
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao
authors.forename: Tomoya
authors.initials: T
authors.lastname: Yukawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hirata
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oda
authors.forename: Jun
authors.initials: J
authors.lastname: Satoh
authors.forename: Tamejiro
authors.initials: T
authors.lastname: Hiyama