title: Regioselective synthesis of 3-(2-hydroxyaryl)pyridines via arynes and pyridine N-oxides.
abstract: A variety of substituted 3-(2-hydroxyphenyl)pyridines have been prepared regioselectively by a transition-metal-free, mild, one-step route, which involves the reaction of pyridine N-oxides with silylaryl triflates in the presence of CsF in acetonitrile at room temperature. These reactions proceed in good yields through what appears to be a series of rearrangements.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
authors.forename: Cristiano
authors.initials: C
authors.lastname: Raminelli
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Liu
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D007202:Indicators and Reagents; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D011725:Pyridines; C013229:pyridine N-oxide