title: Achiral benzophenone ligand-rhodium complex with chiral diamine activator for high enantiocontrol in asymmetric transfer hydrogenation.
abstract: The chirality of an achiral benzophenone-based rhodium complex can be controlled by chiral diamines to afford significantly high enantioselectivity in the catalytic asymmetric transfer hydrogenation of ketones (up to 99% ee, 99% yield).
authors.affiliation: Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo, 152-8552, Japan. kmikami@o.cc.titech.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Mikami
authors.forename: Kazuki
authors.initials: K
authors.lastname: Wakabayashi
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Yusa
authors.forename: Kohsuke
authors.initials: K
authors.lastname: Aikawa
mesh_terms: D001577:Benzophenones / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003959:Diamines / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001577:Benzophenones; D003959:Diamines; D007659:Ketones; D008024:Ligands; D009942:Organometallic Compounds; C047723:benzophenone; D012238:Rhodium