title: Treatment of refractory gastroesophageal reflux disease with radiofrequency energy (Stretta) in patients after Roux-en-Y gastric bypass.
abstract: BACKGROUND
  Morbid obesity is associated with gastroesophageal reflux disease (GERD), which, in most cases, completely resolves after Roux-en-Y gastric bypass (RYGB). Patients with persistent or recurrent symptoms have limited surgical options. This study sought to evaluate the application of the Stretta procedure for patients with refractory GERD.
  
  
  METHODS
  The medical records of all patients who underwent Stretta for refractory GERD after RYGB were reviewed. Demographic, preoperative, and postoperative reflux data were collected. Data are presented as mean +/- standard error of the mean. The t-test was used for comparison purposes.
  
  
  RESULTS
  Of 369 patients, 7 received Stretta 27 +/- 6 months after RYGB. All were women with a mean age of 49 +/- 2 years. All the patients had experienced prebypass GERD symptoms for a duration of 45 +/- 8 months. The mean prebypass body mass index was 45 +/- 2 kg/m(2), and this was reduced to 29 +/- 2 kg/m(2) after laparoscopic RYGB (p < 0.001). Before Stretta, all patients underwent a 48-h Bravo pH study, which demonstrated reflux with a mean fraction time of 7% +/- 2% for pH lower than 4. After Stretta, five patients had complete resolution of their symptoms, with normalization of pH studies (mean fraction time of 3% +/- 0% for pH < 4). The follow-up period after Stretta was 20 +/- 2 months. One patient did not have adequate relief of symptoms after Stretta, and one patient was lost to follow-up evaluation.
  
  
  CONCLUSIONS
  Stretta is a valid option in the treatment of persistent GERD for patients who have undergone gastric bypass. Further study is required to evaluate the long-term efficacy of this procedure.
authors.affiliation: Department of Surgery, Indiana University, Emerson Hall, 545 Barnhill Drive, Suite 242, Indianapolis, IN 46202, USA. smattar@iupui.edu
authors.forename: S G
authors.initials: SG
authors.lastname: Mattar
authors.forename: F
authors.initials: F
authors.lastname: Qureshi
authors.forename: D
authors.initials: D
authors.lastname: Taylor
authors.forename: P R
authors.initials: PR
authors.lastname: Schauer
mesh_terms: D000328:Adult; D017115:Catheter Ablation; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000378:metabolism / Q000601:surgery*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010535:Laparoscopy; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D016896:Treatment Outcome