title: Myelin biogenesis: sorting out protein trafficking.
abstract: Myelin biogenesis is a complex process involving coordinated exocytosis, endocytosis, mRNA transport and cytoskeletal dynamics. Recent studies indicate that soluble neuronal signals may control the surface expression of proteolipid protein, a process that involves reduced endocytosis and/or increased transport carrier recruitment from an intracellular pool.
authors.affiliation: Department of Neuroscience, University of Connecticut Medical School, Farmington, Connecticut 06030, USA.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Anitei
authors.forename: Steven E
authors.initials: SE
authors.lastname: Pfeiffer
mesh_terms: D004705:Endocytosis; D011992:Endosomes / Q000502:physiology; D005089:Exocytosis; D008954:Models, Biological; D018991:Myelin Proteolipid Protein / Q000378:metabolism*; D009186:Myelin Sheath / Q000378:metabolism*; D021381:Protein Transport; D015398:Signal Transduction
chemical_list: D018991:Myelin Proteolipid Protein