Serum fructosamine concentrations in 59 dogs naturally Infected with Angiostrongylus vasorum.
Retrospectively, 89 cases of dogs infected with Angiostrongylus vasorum were examined. Fifty-nine of these 89 dogs fulfilled the criteria of not being dually infected with Crenosoma vulpis as well as having a full biochemistry profile including serum fructosamine available. The mean serum fructosamine value of the 59 dogs was 236 micromol/l (reference value 258-348 micromol/l) and significantly lower than the serum fructosamine level of 314 micromol/l in a control group of 42 clinically healthy dogs. Eleven dogs were available for follow up after successful treatment of angiostrongylosis. In this group, the serum fructosamine value rose from a mean of 244 micromol/l to a mean of 320 micromol/l following treatment. Serum glucose, albumin and protein were all within the respective reference ranges at all sampling points. The results indicate that serum fructosamine could be affected by infection with A. vasorum. Furthermore, this change cannot be explained by measurable changes in the level of glucose, albumin or protein. The clinical impact of this study is that a low fructosamine value may indicate infection with A. vasorum thereby suggesting a Baermann test to be performed.
Willesen
J L
JL
Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, 16 Dyrlaegevej, 1870 Frb. C., Denmark. jwi@kvl.dk
Jensen
A L
AL
Kristensen
A T
AT
Kjelgaard-Hansen
M
M
Jessen
R
R
Koch
J
J
D000801:Angiostrongylus; D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001798:Blood Proteins / Q000032:analysis; D016022:Case-Control Studies; D004283:Dog Diseases / Q000097:blood* / Q000175:diagnosis; D004285:Dogs; D019270:Fructosamine / Q000097:blood*; D012189:Retrospective Studies; D012709:Serum Albumin / Q000032:analysis; D017206:Strongylida Infections / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*
D015415:Biomarkers; D001786:Blood Glucose; D001798:Blood Proteins; D012709:Serum Albumin; D019270:Fructosamine