title: Preparation and characterization of stimuli-resistible hydrogels nano-coated with polyelectrolyte multilayer films.
abstract: Alginate (ALG) hydrogels were nano-coated with polyelectrolyte multilayer (PEM) films composed of poly(diallyldimethyl ammonium chloride) (PDDA) and poly(sodium 4-styrenesulfonate) (PSS). Non- and nano-coated ALG hydrogels were immersed into salt solutions (pH 6, ionic strength: 0.01 M), and the swelling behavior of these ALG hydrogels was observed by optical microscopy. The increases in the diameter of the 10-step coated ALG hydrogels were one fourth or less than that of the non-coated hydrogels. These results indicate that the characteristics of nano-coated ALG hydrogels remain unchanged independent of how the external environment is changed (e.g., pH, ionic strength). Consequently, tolerant ionic hydrogels may be prepared by the nano-coating of hydrogel surfaces with PEM films and may be useful for technological and biomedical applications.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Japan.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Sakaguchi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Serizawa
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Akashi
mesh_terms: D000042:Absorption; D000464:Alginates / Q000737:chemistry*; D001826:Body Fluids / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D020100:Hydrogels / Q000737:chemistry*; D008422:Materials Testing; D008567:Membranes, Artificial; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D010316:Particle Size; D011095:Polyethylenes / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000464:Alginates; D020099:Coated Materials, Biocompatible; D004573:Electrolytes; D006603:Hexuronic Acids; D020100:Hydrogels; D008567:Membranes, Artificial; D011095:Polyethylenes; D011108:Polymers; D000644:Quaternary Ammonium Compounds; D013451:Sulfonic Acids; C041004:poly-N,N-dimethyl-N,N-diallylammonium chloride; D020723:Glucuronic Acid; C077114:styrenesulfonic acid polymer