title: Systemic determinants of gene evolution and function.
authors.forename: Eugene V
authors.initials: EV
authors.lastname: Koonin
mesh_terms: D000818:Animals; D015982:Bias; D019143:Evolution, Molecular; D015870:Gene Expression; D005796:Genes / Q000502:physiology; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D025941:Protein Interaction Mapping; D012441:Saccharomyces cerevisiae / Q000235:genetics; D049490:Systems Biology; D013997:Time Factors