title: MR colonography for the assessment of colonic anastomoses.
abstract: OBJECTIVE
  To assess colonic anastomoses in patients after surgical treatment by means of MR colonography (MRC) in comparison with conventional colonoscopy (CC).
  
  
  METHODS
  A total of 39 patients who had previously undergone colonic resection and end-to-end-anastomosis were included in the study. MRI was based on a dark-lumen approach. Contrast-enhanced T1-weighted (T1w) three-dimensional (3D) images were collected following the rectal administration of water for colonic distension. The MRC data were evaluated by two radiologists. The criteria employed to evaluate the anastomoses included bowel wall thickening and increased contrast uptake in this region. Furthermore, all other colonic segments were assessed for the presence of pathologies.
  
  
  RESULTS
  In 23 and 20 patients the anastomosis was rated to be normal by MRC and CC, respectively. In three patients CC revealed a slight inflammation of the anastomosis that was missed by MRI. A moderate stenosis of the anastomosis without inflammation was detected by MRC in five patients, which was confirmed by CC. In the remaining 11 patients a relevant pathology of the anastomosis was diagnosed by both MRC and CC. Recurrent tumor was diagnosed in two patients with a history of colorectal carcinoma. In the other nine patients inflammation of the anastomosis was seen in seven with Crohn's disease (CD) and two with ulcerative colitis. MRC did not yield any false-positive findings, resulting in an overall sensitivity/specificity for the assessment of the anastomosis of 84%/100%.
  
  
  CONCLUSIONS
  MRC represents a promising alternative to CC for the assessment of colonic anastomoses in patients with previous colonic resection.
authors.affiliation: Medical Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany. ajaj@uke-hamburg.de
authors.forename: Waleed
authors.initials: W
authors.lastname: Ajaj
authors.forename: Mathias
authors.initials: M
authors.lastname: Goyen
authors.forename: Jost
authors.initials: J
authors.lastname: Langhorst
authors.forename: Stefan G
authors.initials: SG
authors.lastname: Ruehm
authors.forename: Guido
authors.initials: G
authors.lastname: Gerken
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Lauenstein
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical / Q000379:methods*; D002277:Carcinoma / Q000473:pathology; D003106:Colon / Q000473:pathology / Q000601:surgery*; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology; D003287:Contrast Media / Q000494:pharmacology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007249:Inflammation; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media