ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data.
CONCLUSIONS
We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression.


BACKGROUND
ACE-it is freely available at http://ibivu.cs.vu.nl/programs/acewww/.
van Wieringen
Wessel N
WN
Department of Mathematics, Vrije Universiteit De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands.
Belien
Jeroen A M
JA
Vosse
Sjoerd J
SJ
Achame
Eskeatnaf M
EM
Ylstra
Bauke
B
D000465:Algorithms; D001483:Base Sequence; D002874:Chromosome Mapping / Q000379:methods*; D003198:Computer Simulation; D018628:Gene Dosage / Q000235:genetics*; D008957:Models, Genetic; D015233:Models, Statistical; D008969:Molecular Sequence Data; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D012313:RNA / Q000235:genetics*; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software; D018511:Systems Integration
D012313:RNA