Synthesis and characterization of glibenclamide complexes of magnesium, chromium, cobalt, nickel, zinc and cadmium salts.
Glibenclamide is the commonly used hypoglycemic agent in NIDDM. Metal complexes of glibenclamide have been synthesized by reaction with different metals such as magnesium, chromium, cobalt, nickel, zinc and cadmium in the form of their chlorides. These complexes were characterized by their physical characteristics, 1H-NMR, IR and Atomic absorption studies.
Zaman
M Kamran
MK
Department of Chemistry, University of Karachi, Karachi-75270.
Arayne
M Saeed
MS
Sultana
Najma
N
Farooq
Afghan
A
D019256:Cadmium Chloride / Q000737:chemistry; D002712:Chlorides / Q000737:chemistry; D017608:Chromium Compounds / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry; D005905:Glyburide / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D007004:Hypoglycemic Agents / Q000138:chemical synthesis*; D015636:Magnesium Chloride / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008670:Metals / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry; D013054:Spectrophotometry, Atomic; D013055:Spectrophotometry, Infrared; D044366:Transition Temperature; D017967:Zinc Compounds / Q000737:chemistry
D002712:Chlorides; D017608:Chromium Compounds; D007004:Hypoglycemic Agents; D008670:Metals; D017967:Zinc Compounds; D015636:Magnesium Chloride; D003035:Cobalt; C022838:nickel chloride; D009532:Nickel; C016837:zinc chloride; C017133:chromous chloride; C018021:cobaltous chloride; D019256:Cadmium Chloride; D005905:Glyburide