Congenital lymphocytic choriomeningitis virus: an underdiagnosed cause of neonatal hydrocephalus.
We report a case of congenital hydrocephalus caused by lymphocytic choriomeningitis virus with severe neurologic sequelae, including hydrocephalus, chorioretinitis, blindness and developmental delay. This is the first report of lymphocytic choriomeningitis virus isolation in the cerebrospinal fluid of a congenitally infected infant.
Schulte
Danica Jenine
DJ
Division of Pediatric Infectious Diseases, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA. Danica.Schulte@cshs.org
Comer
James A
JA
Erickson
Bobbie R
BR
Rollin
Pierre E
PE
Nichol
Stuart T
ST
Ksiazek
Thomas G
TG
Lehman
Deborah
D
D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D007231:Infant, Newborn; D008216:Lymphocytic Choriomeningitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008217:Lymphocytic choriomeningitis virus / Q000302:isolation & purification*; D008297:Male; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed