title: Induction of estrus in bitches with normal and persistent anestrus using human menopausal gonadotropin (hMG).
abstract: Human menopausal gonadotropin (hMG) was administered intramuscularly to 10 bitches during apparently normal anestrus (n = 7) or persistent anestrus (n = 3). Each dog received a 75-IU dose of hMG (75 IU LH and 75 IU FSH; 1 to 7 units/kg) daily for nine days. Nine bitches responded with obvious signs of proestrus within 3 to 9 days. Of these, 3 bitches exhibited a weak proestrus while 2 exhibited a normal estrus and ovulation but failed to become pregnant The remaining 4 bitches became pregnant at the induced cycle and produced normal litters at 72 to 85 d after the start of treatment, including 1 bitch that had been treated at 24 mo after the last estrus. In 2 cases, treatment resulted in ovulation following 25 or 34 mo of chronic pubertal anestrus, 1 of which became pregnant. The results suggest that hMG can be a useful gonadotropin preparation for inducing estrus in dogs.
authors.affiliation: Section of Theriogenology, Faculty of Veterinary Sciences, University of Buenos Aires, Chorroarin 290, 1486 Buenos Aires (Cap. Fed.), Argentina.
authors.forename: M M
authors.initials: MM
authors.lastname: Wanke
authors.forename: J
authors.initials: J
authors.lastname: Farina
authors.forename: M H
authors.initials: MH
authors.lastname: Loza
authors.forename: M
authors.initials: M
authors.lastname: Rebuelto
authors.forename: P W
authors.initials: PW
authors.lastname: Concannon