title: Synthesis and characterization of glibenclamide complexes of magnesium, chromium, cobalt, nickel, zinc and cadmium salts.
abstract: Glibenclamide is the commonly used hypoglycemic agent in NIDDM. Metal complexes of glibenclamide have been synthesized by reaction with different metals such as magnesium, chromium, cobalt, nickel, zinc and cadmium in the form of their chlorides. These complexes were characterized by their physical characteristics, 1H-NMR, IR and Atomic absorption studies.
authors.affiliation: Department of Chemistry, University of Karachi, Karachi-75270.
authors.forename: M Kamran
authors.initials: MK
authors.lastname: Zaman
authors.forename: M Saeed
authors.initials: MS
authors.lastname: Arayne
authors.forename: Najma
authors.initials: N
authors.lastname: Sultana
authors.forename: Afghan
authors.initials: A
authors.lastname: Farooq
mesh_terms: D019256:Cadmium Chloride / Q000737:chemistry; D002712:Chlorides / Q000737:chemistry; D017608:Chromium Compounds / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry; D005905:Glyburide / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D007004:Hypoglycemic Agents / Q000138:chemical synthesis*; D015636:Magnesium Chloride / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008670:Metals / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry; D013054:Spectrophotometry, Atomic; D013055:Spectrophotometry, Infrared; D044366:Transition Temperature; D017967:Zinc Compounds / Q000737:chemistry
chemical_list: D002712:Chlorides; D017608:Chromium Compounds; D007004:Hypoglycemic Agents; D008670:Metals; D017967:Zinc Compounds; D015636:Magnesium Chloride; D003035:Cobalt; C022838:nickel chloride; D009532:Nickel; C016837:zinc chloride; C017133:chromous chloride; C018021:cobaltous chloride; D019256:Cadmium Chloride; D005905:Glyburide