title: Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration.
abstract: Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the principals of gene-enhanced tissue engineering and the techniques of introducing DNA into cells. This manuscript will review recent advances in gene-based therapies for dental hard tissue regeneration, specifically as it pertains to dentin regeneration/pulp capping and periodontal regeneration.
authors.affiliation: Creighton University School of Dentistry, Omaha, NE, USA. pedwards@creighton.edu
authors.forename: Paul C
authors.initials: PC
authors.lastname: Edwards
authors.forename: James M
authors.initials: JM
authors.lastname: Mason