Lycopladines B-D and lyconadin B, new alkaloids from Lycopodium complanatum.
Four new alkaloids, lycopladines B-D (1-3) and lyconadin B (4), have been isolated from the club moss Lycopodium complanatum and the structures including the stereochemistry were elucidated on the basis of spectral data and modified Mosher's method. Lyconadin B (4) elevated NGF mRNA expression in 1321N1 human astrocytoma cells.
Ishiuchi
Kan'ichiro
K
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Kubota
Takaaki
T
Hoshino
Tomohiro
T
Obara
Yutaro
Y
Nakahata
Norimichi
N
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D032502:Lycopodium / Q000737:chemistry*; D008956:Models, Chemical; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000737:chemistry / Q000302:isolation & purification
D000470:Alkaloids; D011083:Polycyclic Compounds; C514204:lyconadin B