title: Short term efficacy of a lifestyle intervention programme on cardiovascular health outcome in overweight Indigenous Australians with and without type 2 diabetes mellitus. The healthy lifestyle programme (HELP).
abstract: We aim to examine the short-term efficacy of a lifestyle intervention programme on cardiovascular risk factors in overweight urban Indigenous Australians with and without type 2 diabetes mellitus. One hundred and one urban Indigenous Australians in Queensland voluntarily participated in a culturally appropriate lifestyle intervention programme based on improving physical activity and dietary intake; 44 had type 2 diabetes, 11 had impaired fasting glucose and 46 were euglycaemic. Efficacy of the intervention on biochemical and physical markers of cardiovascular outcome will be monitored over 2 years. Diabetic subjects were overweight with good but suboptimal control of cardiovascular risk factors (mean systolic blood pressure 132 mmHg, diastolic blood pressure 85 mmHg, LDL cholesterol 2.8mM and urine albumin to creatinine ratio 10.8) at baseline. At the 6 months follow up, there were significant reductions in waist circumference (3.1cm, P=0.01) and diastolic blood pressure (4.6 mmHg, P=0.01). Although modest, these changes may improve clinical outcome if sustained.
authors.affiliation: Discipline of Medicine, The University of Queensland, The Prince Charles Hospital, Chermside, Qld 4032, Australia. lchan@ccs.uq.edu.au
authors.forename: Lionel C K
authors.initials: LC
authors.lastname: Chan
authors.forename: Robert
authors.initials: R
authors.lastname: Ware
authors.forename: Janine
authors.initials: J
authors.lastname: Kesting
authors.forename: Maureen
authors.initials: M
authors.lastname: Marczak
authors.forename: David
authors.initials: D
authors.lastname: Good
authors.forename: Joanne T E
authors.initials: JT
authors.lastname: Shaw
mesh_terms: D015331:Cohort Studies; D003404:Creatinine / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008019:Life Style; D008297:Male; D050177:Overweight / Q000502:physiology*; D010353:Patient Education as Topic; D010809:Physical Fitness; D044382:Population Groups / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011793:Queensland; D016896:Treatment Outcome
chemical_list: D003404:Creatinine