title: Ophthalmological outcome following orbital resection in anterior and anterolateral skull base surgery.
abstract: OBJECTIVE
  Partial resection of the orbital bones is not uncommon during the excision of anterior and anterolateral skull base tumors. Controversy exists regarding the need for and extent of the reconstruction necessary following this resection. The authors studied this factor in a series of patients.
  
  
  METHODS
  The authors conducted a retrospective review of 56 patients in whom resection of 57 anterior or anterolateral skull base tumors and partial excision of the orbital bone were performed. Adverse ophthalmological outcomes were noted in 16 patients, in nine of whom adverse outcomes were believed to be directly related to resection of the orbital walls. Some degree of orbital reconstruction was performed during 23 of the 57 procedures. An adverse orbit-related outcome was strongly associated with resection of the orbital floor and with resection of two thirds or more of two or more orbital walls but not with the presence of absence or orbital reconstruction. The latter finding, however, is likely a function of selection bias.
  
  
  CONCLUSIONS
  In most patients after partial excision of the orbital bones, elaborate reconstruction is not necessary. Isolated medial and lateral orbital wall defects or combined superior and lateral orbital wall defects, especially in cases in which the periorbita is intact, probably do not require primary reconstruction. In cases of orbital floor defects, whether isolated or part of a multiple wall resection, primary reconstruction is recommended.
authors.affiliation: Department of Neurosurgery, University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA. fdemonte@mdanderson.org
authors.forename: F
authors.initials: F
authors.lastname: DeMonte
authors.forename: P
authors.initials: P
authors.lastname: Tabrizi
authors.forename: S A
authors.initials: SA
authors.lastname: Culpepper
authors.forename: D
authors.initials: D
authors.lastname: Abi-Said
authors.forename: C N
authors.initials: CN
authors.lastname: Soparkar
authors.forename: J R
authors.initials: JR
authors.lastname: Patrinely
mesh_terms: D003399:Craniotomy / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D009915:Orbit / Q000601:surgery; D009918:Orbital Neoplasms / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D019291:Skull Base / Q000601:surgery; D019292:Skull Base Neoplasms / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome