Control of function of a small peptide by a protein.
A peptide that functions only in the presence of a protein has been developed using reaction-based selection from peptide phage libraries. The peptide was not functional in the absence of the protein, but formed enaminones with 1,3-diketone derivatives when bound to the protein.
Tanaka
Fujie
F
Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. ftanaka@scripps.edu
Fuller
Roberta
R
D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000502:physiology*; D011506:Proteins / Q000502:physiology*; D055672:Static Electricity
D010455:Peptides; D011506:Proteins