title: Conventional systemic agents for psoriasis. A systematic review.
abstract: Very few well designed studies have evaluated the conventional systemic agents for psoriasis. This is a systematic, evidence-based review of the literature evaluating both the efficacy and safety of the medications cyclosporine, methotrexate, acitretin, hydroxyurea, and 6-thioguanine. Treatment recommendations are made.
authors.affiliation: New York University School of Medicine, New York, New York 10016, USA. Strober@nyc.rr.com
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Strober
authors.forename: Kimberly
authors.initials: K
authors.lastname: Siu
authors.forename: Kavi
authors.initials: K
authors.lastname: Menon
mesh_terms: D017255:Acitretin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D011565:Psoriasis / Q000188:drug therapy* / Q000503:physiopathology; D013866:Thioguanine / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D013866:Thioguanine; D017255:Acitretin; D006918:Hydroxyurea; D008727:Methotrexate