title: Protein degradation by the ubiquitin-proteasome pathway in normal and disease states.
authors.affiliation: Nephrology Division, Beth Isreal Deaconess, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Stewart H
authors.initials: SH
authors.lastname: Lecker
authors.forename: Alfred L
authors.initials: AL
authors.lastname: Goldberg
authors.forename: William E
authors.initials: WE
authors.lastname: Mitch
mesh_terms: D007674:Kidney Diseases / Q000378:metabolism; D009124:Muscle Proteins / Q000378:metabolism; D009133:Muscular Atrophy / Q000503:physiopathology; D009210:Myofibrils / Q000201:enzymology; D009369:Neoplasms / Q000628:therapy; D046988:Proteasome Endopeptidase Complex / Q000276:immunology / Q000502:physiology*; D061988:Proteasome Inhibitors; D046188:Protein Modification, Translational / Q000502:physiology; D011506:Proteins / Q000378:metabolism*; D025801:Ubiquitin / Q000502:physiology*; D044764:Ubiquitin-Activating Enzymes / Q000502:physiology*
chemical_list: D009124:Muscle Proteins; D061988:Proteasome Inhibitors; D011506:Proteins; D025801:Ubiquitin; D046988:Proteasome Endopeptidase Complex; D044764:Ubiquitin-Activating Enzymes