Efficacy of cotrimoxazole and rifampin for 6 or 8 weeks of therapy in childhood brucellosis.
From March 1998 to September 2001, 64 children and from October 2001 to December 2004, 66 children < or = 15 years with brucellosis in Babol, Iran, were treated with cotrimoxazole and rifampin for 6 or 8 weeks, respectively. Cure rate for 6 weeks was 89.1% and for 8 weeks it was 95.5%. Six weeks of therapy with cotrimoxazole plus rifampin is sufficient for treatment of childhood brucellosis.
Roushan
Mohammad Reza Hasanjani
MR
Department of Infectious Diseases, Yahyanejad Hospital, Babol, Iran. hagar2q@yahoo.ca
Mohraz
Mino
M
Janmohammadi
Nasser
N
Hajiahmadi
Mahmood
M
D000293:Adolescent; D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran; D008297:Male; D012189:Retrospective Studies; D012293:Rifampin / Q000008:administration & dosage*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage*
D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D012293:Rifampin