title: Alveolar hemorrhage associated with platelet glycoprotein IIb/IIIa receptor inhibitors.
abstract: Platelet glycoprotein IIb/IIIa receptor inhibitors have been shown to improve outcomes in percutaneous coronary interventions. Their use with multiple anticoagulants has been associated with increased bleeding complications. Among these, alveolar hemorrhage is a rare and potentially fatal complication. Six patients with this complication were identified over a four-year period. Patient characteristics, possible risk factors, pathophysiology, prevention and potential treatment options are discussed.
authors.affiliation: Temple University School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: Rasih Atilla
authors.initials: RA
authors.lastname: Ener
authors.forename: Nichole
authors.initials: N
authors.lastname: Bruno
authors.forename: Daniel
authors.initials: D
authors.lastname: Dadourian
authors.forename: Nelson
authors.initials: N
authors.lastname: Wolf
authors.forename: William
authors.initials: W
authors.lastname: Van Decker
authors.forename: James
authors.initials: J
authors.lastname: Burke
authors.forename: Michael
authors.initials: M
authors.lastname: Styler
authors.forename: David
authors.initials: D
authors.lastname: Topolsky
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000188:drug therapy* / Q000453:epidemiology; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D011650:Pulmonary Alveoli / Q000098:blood supply*; D012307:Risk Factors
chemical_list: D000925:Anticoagulants; D019039:Platelet Glycoprotein GPIIb-IIIa Complex