title: Immediate placement of implants in periapical infected sites: a prospective randomized study in 50 patients.
abstract: OBJECTIVE
  To determine clinical success when implants are placed in chronic periapical infected sites.
  
  
  METHODS
  Fifty patients (25 females, 25 males, mean age 39.7 +/- 14.5 years) were included in this prospective controlled study. After randomization, 25 Frialit-2 Synchro implants were immediately placed (IP) after extraction, and 25 Frialit-2 Synchro implants were placed after a 3-month healing period (DP). Thirty-two implants were placed in the anterior maxilla and 18 implants were placed in the premolar region. Implant survival, mean Implant Stability Quotient (ISQ) values, gingival aesthetics, radiographic bone loss, and microbiologic characteristics of periapical lesions were evaluated for both groups.
  
  
  RESULTS
  Overall, 2 implants belonging to the IP group were lost, resulting in a survival rate of 92% for IP implants versus 100% for DP implants. Mean ISQ, gingival aesthetics and radiographic bone resorption, and periapical cultures were not significantly different with the IP and DP implants.
  
  
  CONCLUSIONS
  Immediate implant placement in chronic periapical lesions may be indicated.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. j.a.lindeboom@amc.uva.nl
authors.forename: Jérôme A H
authors.initials: JA
authors.lastname: Lindeboom
authors.forename: Yang
authors.initials: Y
authors.lastname: Tjiook
authors.forename: Frans H M
authors.initials: FH
authors.lastname: Kroon
mesh_terms: D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging; D001421:Bacteria, Anaerobic / Q000302:isolation & purification; D016025:Bone Transplantation; D002908:Chronic Disease; D003758:Dental Implantation, Endosseous / Q000009:adverse effects / Q000379:methods*; D019250:Dental Implants, Single-Tooth; D019232:Dental Restoration Failure; D005260:Female; D005889:Gingival Recession / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010485:Periapical Periodontitis / Q000601:surgery*; D011446:Prospective Studies; D011859:Radiography; D018709:Statistics, Nonparametric; D013997:Time Factors; D020390:Tooth Socket / Q000601:surgery*; D016896:Treatment Outcome