Practical designed syntheses of all stereoisomeric bis(2,2')- and tris(2,2',2' ')-tetrahydrofurans.
A convenient synthetic entry to the entire group of bis(2,2')- and tris(2,2',2' ')-tetrahydrofurans has been developed. The method is concise and relies on chromatographic separation, decarbonylation, and annulation to arrive at a specific product of defined relative configuration. [reaction: see text]
Paquette
Leo A
LA
Evans Chemical Laboratories, The Ohio State University, Columbus, OH 43210, USA. paquette.1@osu.edu
Hilmey
David G
DG
Gallucci
Judith C
JC