Characterization of single nucleotide polymorphisms in sheep and their variation as evidence of selection.
The discovery of SNPs was performed using animals from eight European sheep breeds. Eleven SNPs were further characterized using about 1,700 sheep belonging to 57 breeds. A method for the identification of loci that were likely subject to selection was applied; three of the 11 SNPs lying outside the 95% confidence region of the conditional joint distribution of F(ST) and mean heterozygosity were identified as outliers.
Pariset
L
L
Dipartimento di Produzioni Animali, Università della Tuscia, Viterbo, Italy. pariset@unitus.it
Cappuccio
I
I
Joost
S
S
D'Andrea
M
M
Marletta
D
D
Ajmone Marsan
P
P
Valentini
A
A
D000818:Animals; D005260:Female; D005838:Genotype; D006579:Heterozygote; D008297:Male; D020641:Polymorphism, Single Nucleotide; D012641:Selection, Genetic; D017422:Sequence Analysis, DNA; D012756:Sheep / Q000235:genetics*