title: Functionality dependent olefin activity in acyclic diene metathesis polymerization: mass spectrometry characterization of amino acid functionalized olefins.
abstract: Mass spectrometry has become an essential tool in delineating the structural properties of a new series of amino acid functionalized acyclic diene metathesis (ADMET) polymers known as bioolefins. These measurements, coupled with the measurement of the polymers chemical and physical properties, assist in the determination of their utility as biomaterials. In the present study, a set of five polymers with different bulk size and electronic properties were chosen for structural analyses by MALDI-TOF, MALDI-FTICR, and DIOS-TOF. The obtained data show that due to the competing metathesis and isomerization during ADMET, depending on their structural properties, the olefins display different selectivity toward main metathesis or isomerized products.
authors.affiliation: Department of Chemistry, Mass Spectrometry Laboratory, University of Florida, P. O. Box 117200, Gainesville, Florida 32611-7200, USA.
authors.forename: Violeta I
authors.initials: VI
authors.lastname: Petkovska
authors.forename: Timothy E
authors.initials: TE
authors.lastname: Hopkins
authors.forename: David H
authors.initials: DH
authors.lastname: Powell
authors.forename: Kenneth B
authors.initials: KB
authors.lastname: Wagener
mesh_terms: D000144:Acids, Acyclic / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry* / Q000378:metabolism*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D019281:Dimerization; D007536:Isomerism; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*; D013237:Stereoisomerism
chemical_list: D000144:Acids, Acyclic; D000475:Alkenes; D000596:Amino Acids; D011108:Polymers