title: Release of nitric oxide from a sol-gel hybrid material containing a photoactive manganese nitrosyl upon illumination with visible light.
abstract: A polyurethane-coated sol-gel material containing the photoactive Mn nitrosyl [Mn(PaPy3)(NO)]ClO4 rapidly releases NO with high quantum efficiency when exposed to visible light of low intensity. This rigid and strongly colored hybrid material is a convenient point source of NO that can only be triggered with light. Successful delivery of NO to biological targets, such as proteins, by this material has also been demonstrated.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA.
authors.forename: Aura A
authors.initials: AA
authors.lastname: Eroy-Reveles
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Leung
authors.forename: Pradip K
authors.initials: PK
authors.lastname: Mascharak
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D008027:Light; D008422:Materials Testing; D015394:Molecular Structure; D009569:Nitric Oxide / Q000737:chemistry*; D020030:Nitric Oxide Donors / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D044367:Phase Transition; D010777:Photochemistry
chemical_list: D001672:Biocompatible Materials; D020030:Nitric Oxide Donors; D009942:Organometallic Compounds; C517228:nitrosyl(N,N'-bis(2-pyridylmethyl)amine-N-ethyl-2-pyridine-2-carboxamide)manganese(II); D009569:Nitric Oxide