New hope for infertility therapy: fabricating gametes from stem cells.
The field of reproductive and developmental biology has been revolutionized by recent advanced studies. These studies indicate that stem cells are capable of forming gametes in vivo and in vitro in both mouse and human. This has provided powerful tools for undertaking new types of reproductive studies, and particularly might provide new technology and novel approaches in assisted reproductive medicine.
Feng
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HL
Department of Obstetrics and Gynecology, Center for Human Reproduction, North Shore University Hospital, NYU School of Medicine, Manhasset, New York 11030, USA. hfeng@nshs.edu
Han
Y B
YB
Hershlag
A
A
Yang
H
H
D000818:Animals; D001755:Blastocyst / Q000166:cytology; D002454:Cell Differentiation; D005260:Female; D005298:Fertility / Q000502:physiology; D005854:Germ Cells / Q000166:cytology*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D051379:Mice; D009865:Oocytes / Q000166:cytology / Q000502:physiology; D013094:Spermatozoa / Q000166:cytology / Q000502:physiology; D013234:Stem Cells / Q000166:cytology / Q000502:physiology