Sex cells: dissecting the functions of fruitless isoforms.
Behavioral and developmental sexual dimorphism in fruitflies is related to male-specific expression of protein isoforms encoded by the fruitless gene. A recent study shows that the wide-scale effects of fruitless are associated with differential functions of individual protein isoforms.
Douglas
Scott J
SJ
Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road., Mississauga, Ontario L5L 1C6, Canada.
Levine
Joel D
JD
D000818:Animals; D029721:Drosophila Proteins / Q000235:genetics / Q000502:physiology*; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology*; D005260:Female; D008297:Male; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000502:physiology*; D020033:Protein Isoforms / Q000502:physiology; D012727:Sex Characteristics; D012726:Sexual Behavior, Animal; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*
D029721:Drosophila Proteins; D009419:Nerve Tissue Proteins; D020033:Protein Isoforms; D014157:Transcription Factors; C103226:fru protein, Drosophila