Topiramate induces type 3 renal tubular acidosis by inhibiting renal carbonic anhydrase.
Sacré
Anne
A
Jouret
François
F
Manicourt
Daniel
D
Devuyst
Olivier
O
D000141:Acidosis, Renal Tubular / Q000139:chemically induced* / Q000201:enzymology; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D002256:Carbonic Anhydrases / Q000378:metabolism*; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D008954:Models, Biological; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose; D002256:Carbonic Anhydrases