title: [Hemorrhoidal thrombosis. A clinical and therapeutical study on 22 consecutive patients].
abstract: Hemorrhoidal thrombosis (HT) represents one of the most frequent complication of hemorrhoids. The two main modalities of clinical presentation are thrombosed of a single external pile or as massive thrombosis (MT), both representing an harmfull condition for the patient which can be usually treated with surgical intervention on an outptient basis. The etiopathogenesis of the disease is nowadays obscure and few investigated till now in the international literature. The Authors performed a prospective study on 22 patients with HT aimed at clarifying the ethiopathogenesis of the disease through the evaluation of the emocoagulative profile of these patients. All the main coagulopathy indexes such as aPT, APTT, Fibrinogen, AT III, XDP, aPCR and LAC resulted normal, while the products of prothrombin degradation (F1 + F2) showed higher values in respect of the control group (p < 0.0001). Our study seems to highlight that HT could not be considered a sistemic or local coagulopathy, so far surgical management of the disease remains the gold standard, as confirmed in our series.
authors.affiliation: Dipartimento di Chirurgia Generale e Trapianti d'Organo, Università degli Studi La Sapienza, Istituto Paride Stefanini, Policlinico Umberto I, Roma.
authors.forename: Fabio
authors.initials: F
authors.lastname: Gaj
authors.forename: Antonello
authors.initials: A
authors.lastname: Trecca
authors.forename: Marianna
authors.initials: M
authors.lastname: Suppa
authors.forename: Massimo
authors.initials: M
authors.lastname: Sposato
authors.forename: Alessandro
authors.initials: A
authors.lastname: Coppola
authors.forename: Gaetano
authors.initials: G
authors.lastname: De Paola
authors.forename: Francesco
authors.initials: F
authors.lastname: Aguglia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006484:Hemorrhoids / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013927:Thrombosis / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000628:therapy