title: The biosynthesis of squalene and sterols by the adipose tissue of rat, sheep and man.
abstract: 1. The subcutaneous and omental adipose tissue of man, the epididymal fat pads of the rat and the fat tail of the Syrian sheep incorporate mevalonic acid into non-saponifiable lipids. 2. Time studies showed that the rates of decarboxylation of mevalonic acid and synthesis of non-saponifiable lipids slightly decline after 20min. but subsequently remain linear for 6hr. 3. About one-half of the incorporated radioactivity in the non-saponifiable lipids was in squalene, 20% in lanosterol and cholesterol, and the remainder in unidentified substances.
authors.affiliation: Department of Biochemistry, School of Medicine, American University of Beirut, Beirut, Lebanon.
authors.forename: I F
authors.initials: IF
authors.lastname: Durr