title: Effect of preinfarction angina pectoris on myocardial blush grade after reperfusion in first anterior wall acute myocardial infarction.
abstract: BACKGROUND
  The aim of the present study was to clarify the effect of preinfarction angina pectoris (PIA) on myocardial blush grade (MBG), a simple marker of myocardial tissue-level reperfusion, in acute myocardial infarction (AMI).
  
  
  RESULTS
  One hundred forty-two patients with first anterior wall AMI who were admitted within 6 h after onset of symptoms were examined. PIA was defined as typical chest pain within 48 h before onset of symptoms. MBG was evaluated by coronary angiography after reperfusion. Patients with MBG 2 or 3 (n=103) had a higher frequency of PIA and a lower frequency of diabetes mellitus than those with MBG 0 or 1 (n=39) (57% vs 28%, p=0.004, and 23% vs 44%, p=0.03, respectively). The former had a lower peak creatine kinase level and a greater left ventricular ejection fraction at predischarge than the latter (3,652+/-2,440 vs 5,507+/-3,058 IU/L, p=0.0002, and 57+/-12% vs 45+/-11%, p<0.0001, respectively). Multivariate logistic regression analysis showed that PIA (p=0.004) and diabetes mellitus (p=0.03) were independently associated with MBG 2 or 3 after reperfusion.
  
  
  CONCLUSIONS
  PIA has beneficial effects on myocardial tissue-level reperfusion evaluated by MBG in first anterior wall AMI.
authors.affiliation: Second Department of Internal Medicine, Faculty of Medicine, Oita University, Hasama, Oita, Japan. akira@med.oita-u.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Tamura
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Shinozaki
authors.forename: Toru
authors.initials: T
authors.lastname: Watanabe
authors.forename: Toru
authors.initials: T
authors.lastname: Nakaishi
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Nagase
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kadota
mesh_terms: D000208:Acute Disease; D000368:Aged; D000787:Angina Pectoris / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D017023:Coronary Angiography; D048909:Diabetes Complications / Q000000981:diagnostic imaging; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D015425:Myocardial Reperfusion; D011237:Predictive Value of Tests; D016277:Ventricular Function, Left