LC-ESI-MS/MS determination of phenylurea and triazine herbicides and their dealkylated degradation products in oysters.
A method was developed for the determination of several phenylurea and triazine herbicides and their transformation products in oysters at the low microg/kg level. Pressurised liquid extraction (PLE) of lyophilisated samples had required successive SPE combined with a liquid/liquid extraction to provide relatively clean extracts for the determination in LC-MS/MS. This procedure was validated according to the 2002/657/EC analytical decision. Efficiency of the analytical method led to confirmatory CCalpha values ranging from 0.1 to 14 microg/kg with an R.S.D. value ranging from 14% to 66% and a recovery yield ranging from 32% to 46% for phenylureas and from 29% to 75% for triazines.
Bichon
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E
LABERCA-LABoratoire d'Etude des Résidus et Contaminants dans les Aliments, Ecole Nationale Vétérinaire de Nantes, route de Gachet, BP 50707, 44307 Nantes cedex 3, France. laberca@vet-nantes.fr
Dupuis
M
M
Le Bizec
B
B
André
F
F
D000818:Animals; D002853:Chromatography, Liquid / Q000379:methods*; D006540:Herbicides / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D010125:Ostreidae / Q000737:chemistry*; D010671:Phenylurea Compounds / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014227:Triazines / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification
D006540:Herbicides; D010671:Phenylurea Compounds; D014227:Triazines