Variation in exocrine pancreatic secretion in rats due to different commercial diets.
The diet fed to laboratory animals is one of many variables that can confound research results. The authors investigated the effect of the composition of commercial standard rodent diets on exocrine pancreatic function in rats. They compared two widely used commercial animal diets and found that diet composition greatly influences pancreatic secretion. Their results indicate that commercial diets should conform to the recommended composition requirements to avoid alterations in physiological functions that would eventually affect the results of biomedical research and that investigators should be keenly aware of the composition of the diets being fed to their animals.
Sabbatini
María Eugenia
ME
Cátedras de Fisiopatologíaa, Universidad de Buenos Aires, Junin 956-Piso 7, 1113 Buenos Aires, Argentina.
Pellegrino
Néstor
N
Rios
Mariana
M
Bianciotti
Liliana G
LG
Vatta
Marcelo S
MS
D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight / Q000502:physiology; D008297:Male; D010179:Pancreas / Q000378:metabolism*; D010189:Pancreatic Juice / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012633:Secretin / Q000378:metabolism; D012844:Sincalide / Q000378:metabolism
D012633:Secretin; D012844:Sincalide