title: Diffusion weighted imaging of cerebellar lesions in Wernicke's encephalopathy.
abstract: We report unusual findings on MR imaging in a 62-year-old woman with Wernicke's encephalopathy (WE). Initial fluid-attenuated inversion recovery (FLAIR) and diffusion weighted MR imaging (DW-MRI) showed hyperintense lesions in the cerebellum and medial thalami, with a decreased apparent diffusion coefficient (ADC) in the cerebellum (reduced by 45%). After thiamine supplementation, the T2 and diffusion hyperintensities disappeared. However, clinical examination at three months showed persistent cerebellar impairment. The importance of the ADC values should be further investigated.
authors.affiliation: Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Paris.
authors.forename: B
authors.initials: B
authors.lastname: Lapergue
authors.forename: I
authors.initials: I
authors.lastname: Klein
authors.forename: J M
authors.initials: JM
authors.lastname: Olivot
authors.forename: P
authors.initials: P
authors.lastname: Amarenco
mesh_terms: D002526:Cerebellar Diseases / Q000188:drug therapy / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008875:Middle Aged; D013831:Thiamine / Q000627:therapeutic use; D014899:Wernicke Encephalopathy / Q000188:drug therapy / Q000473:pathology*
chemical_list: D013831:Thiamine