Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases.
Hu
Xiaoyi
X
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.
Addlagatta
Anthony
A
Matthews
Brian W
BW
Liu
Jun O
JO
D000626:Aminopeptidases / Q000037:antagonists & inhibitors*; D000818:Animals; D002417:Cattle; D049109:Cell Proliferation / Q000187:drug effects; D042783:Endothelial Cells / Q000187:drug effects; D006023:Glycoproteins / Q000037:antagonists & inhibitors*; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D063208:Methionyl Aminopeptidases; D011743:Pyrimidines / Q000494:pharmacology*
D006023:Glycoproteins; D011743:Pyrimidines; D000626:Aminopeptidases; C506619:METAP1 protein, human; C081311:METAP2 protein, human; D063208:Methionyl Aminopeptidases; C030986:pyrimidine