[Dystrophic calcinosis cutis after subcutaneous administration of para-aminosalicylic acid for treatment of pulmonary tuberculosis].
An 81-year-old women presented with monstrous subcutaneous mobile masses on the ventral and ventrolateral surfaces of her thighs. Radiography as well as computer tomography showed extensive soft tissue calcifications. We interpreted these alterations as dystrophic calcinosis cutis, most likely resulting from repeated subcutaneous PAS infusions for the treatment of pulmonary tuberculosis.
Meissner
Markus
M
Klinik für Dermatologie, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Deutschland. meissner.markus@gmx.de
Varwig
Domenica
D
Beier
Christian
C
Jacobi
Volkmar
V
Kaufmann
Roland
R
Gille
Jens
J
D000369:Aged, 80 and over; D010131:Aminosalicylic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002114:Calcinosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D018450:Disease Progression; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D012871:Skin Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D040521:Subcutaneous Tissue / Q000000981:diagnostic imaging / Q000187:drug effects; D013848:Thigh; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents; D010131:Aminosalicylic Acid