Sister Mary Joseph's nodule as presenting sign of a desmoplastic small round cell tumor.
Umbilical metastases, also named Sister Mary Joseph's nodules, are well documented in the adult population and most often represent an underlying intra-abdominal malignancy, usually a carcinoma of gastrointestinal or gynecologic origin. They are indicative of widespread abdominal disease and are associated with a poor prognosis. An extensive review of the literature reveals only two such presentations in the pediatric population. A 14-year-old male presented with an umbilical mass, which was found to be a metastatic lesion of a desmoplastic small round cell tumor (DSRCT) of the abdomen. The diagnosis of an intra-abdominal malignancy, most commonly a DSRCT, should be considered in the presence of an umbilical mass in a child.
Doros
Leslie
L
Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Kaste
Sue C
SC
Rodriguez-Galindo
Carlos
C
D000008:Abdominal Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D014472:Umbilicus / Q000473:pathology* / Q000601:surgery