title: Anterior mitral leaflet reconstruction with pericardium in a 1.9 kg infant with endocarditis.
abstract: A premature twin of 1.9 kg had mitral valve endocarditis develop during neonatal intensive care. Vegetation involving the entire anterior mitral valve leaflet was identified. Reconstruction was achieved by near complete resection of the anterior mitral valve leaflet and retention of the peripheral margin of coaptation including primary and secondary chordae. The body of the anterior mitral valve leaflet was reconstructed using fresh autologous pericardium, a technique not previously reported in an infant of this size. Three and a half years later, the child is well and has required no further intervention.
authors.affiliation: Professor Eoin O'Malley National Centre for Cardiothoracic Surgery, Mater Misericordiae University Hospital, Dublin, Ireland. cardiothoracic@eircom.net
authors.forename: David G
authors.initials: DG
authors.lastname: Healy
authors.forename: Alfred E
authors.initials: AE
authors.lastname: Wood
mesh_terms: D001705:Bioprosthesis; D001724:Birth Weight; D002216:Captopril / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004200:Diseases in Twins / Q000601:surgery; D004232:Diuretics / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000601:surgery*; D016106:Methicillin Resistance; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D010496:Pericardium / Q000637:transplantation; D012293:Rifampin / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000601:surgery*; D014182:Transplantation, Autologous; D014430:Twins, Monozygotic; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D004232:Diuretics; D005839:Gentamicins; D014640:Vancomycin; D002216:Captopril; D012293:Rifampin