title: Quality of life and psychosocial situation before and after a lung, liver or an allogeneic bone marrow transplant.
abstract: OBJECTIVE
  Only few comparative prospective studies have been published on psychosocial issues of organ transplant. This study investigated patient groups with various organ transplants with respect to their quality of life and psychosocial situation before and after surgery.
  
  
  METHODS
  76 patients receiving an organ transplant (lung n = 22, liver n = 26, allogeneic bone marrow n = 28) were investigated with regard to quality of life (SF-36), life satisfaction (FLZ), social support (F-SozU), and psychological symptoms (HADS-D) before (T0) as well as six (T1) and twelve (T2) months after transplant.
  
  
  RESULTS
  In the pre-transplant period the values of the psychosocial variables were partly lower than those of the community normal sample. After transplant lung and bone marrow patients reported less anxiety and depression and a higher life satisfaction, and liver patients reported less depression, compared to the norms. Quality of life, life satisfaction and psychological symptoms of all patients improved significantly post-transplant, whereas the perceived social support decreased. Contrary to the other groups, the psychological well-being of liver transplant recipients was deteriorating between T1 and T2.
  
  
  CONCLUSIONS
  An organ transplant improved the patients' quality of life and psychosocial situation to a great extent. This effect was better in lung and bone marrow than in liver transplant patients.
authors.affiliation: Department of Psychsocial Medicine, University Hospital Zurich. lutz.goetzmann@usz.ch
authors.forename: Lutz
authors.initials: L
authors.lastname: Goetzmann
authors.forename: Richard
authors.initials: R
authors.lastname: Klaghofer
authors.forename: Regula
authors.initials: R
authors.lastname: Wagner-Huber
authors.forename: Jörg
authors.initials: J
authors.lastname: Halter
authors.forename: Annette
authors.initials: A
authors.lastname: Boehler
authors.forename: Beat
authors.initials: B
authors.lastname: Muellhaupt
authors.forename: Urs
authors.initials: U
authors.lastname: Schanz
authors.forename: Claus
authors.initials: C
authors.lastname: Buddeberg
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016026:Bone Marrow Transplantation / Q000523:psychology / Q000534:rehabilitation; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000523:psychology / Q000534:rehabilitation; D016040:Lung Transplantation / Q000523:psychology / Q000534:rehabilitation; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D012944:Social Support; D012959:Socioeconomic Factors; D013557:Switzerland