[Genetic polymorphism of estrogen receptor alpha--a risk factor of osteoporosis?].
Considering the prolonged population lifetime, there is an increasing number of elderly people suffering from osteoporosis. At present the prevention of osteoporosis is one of the most important problems in medicine. The development of genetic investigations and molecular biology gives new possibilities for discovering risk factors and early prevention of this condition. This is a brief summary referring the polymorphisms of estrogen receptors and their significance in the pathogenesis and prevention of osteoporosis.
Drews
Krzysztof
K
Klinika Perinatologii i Chorób Kobiecych, Katedry Perinatologii i Ginekologii AM w Poznaniu.
Seremak-Mrozikiewicz
Agnieszka
A
Bartkowiak-Wieczorek
Joanna
J
Mrozikiewicz
Przemysław M
PM
D015519:Bone Density / Q000235:genetics*; D047628:Estrogen Receptor alpha / Q000235:genetics*; D047629:Estrogen Receptor beta / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D010024:Osteoporosis / Q000235:genetics* / Q000517:prevention & control; D015663:Osteoporosis, Postmenopausal / Q000235:genetics; D011110:Polymorphism, Genetic / Q000235:genetics*
D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta