title: [Proinflammatory and proallergic cytokines in the pathology of developmental age].
abstract: Cytokines are a heterogenic group of proteins with high biological activity, synthesized and secreted by given cells or group of cells taking part in growth or their multiplication, and also in the course of immune and inflammatory reactions. They are responsible for morphological and functional conditions of numerous organs and systems, and for local and general immune responses with accompanying clinical symptoms. The role of cytokines as mediators of inflammatory and allergic reactions seems to be particularly important. Cytokine activity manifested in the final biological effect, is regulated by many substances present in the environment surrounding the effector cell i.e. specific inhibitors, humoral and growth factors. The effect of final cytokine activity in the organism does not take place in the isolated environment, but in the system of interactions and correlations known as the cytokine network.
authors.affiliation: Zakład Pielegniarstwa Pediatrycznego, Akademia Medyczna, ul. Waszyngtona 15, 15-745 Białystok, Poland. emaciorkowska@o2.pl
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Maciorkowska
authors.forename: Maciej
authors.initials: M
authors.lastname: Kaczmarski
mesh_terms: D016207:Cytokines / Q000378:metabolism*; D006803:Human Development / Q000502:physiology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007111:Immunity, Cellular; D007249:Inflammation / Q000276:immunology; D018836:Inflammation Mediators / Q000378:metabolism; D018121:Receptors, Cytokine / Q000378:metabolism*
chemical_list: D016207:Cytokines; D018836:Inflammation Mediators; D018121:Receptors, Cytokine