Evaluation of the tissue response to MTA and MBPC: Microscopic analysis of implants in alveolar bone of rats.
The aim of this study was to evaluate and compare the quantitative and qualitative inflammatory responses and bone formation potential after implantation of polyethylene tubes filled with a new calcium hydroxide containing sealer (MBPc) and ProRoot mineral trioxide aggregate (MTA). There were 48 Wistar rats divided in three groups: Group I (control group) empty polyethylene tubes were implanted in the extraction site; group II and III, polyethylene tubes were implanted filled with ProRoot mineral trioxide aggregate (MTA) and MBPc, respectively. At 7, 15, and 30 days after tube implantation, the animals were killed, the hemi-maxillas were removed and prepared to light microscopic analyses. The scores obtained were submitted to Kruskal-Wallis statistical test (p < 0.05). Significant differences between the materials were not observed. The results showed that both materials had similar biological response.
Cintra
Luciano Tavares Angelo
LT
Department of Endodontics of the Dentistry Faculty of the State University of Campinas, UNICAMP, Piracicaba, SP, Brazil. lucianocintra@fop.unicamp.br
de Moraes
Ivaldo Gomes
IG
Estrada
Bernabé Pedro Felício
BP
Gomes-Filho
João Eduardo
JE
Bramante
Clóvis Monteiro
CM
Garcia
Roberto Brandão
RB
Bernardinelli
Norberti
N
D017607:Aluminum Compounds / Q000737:chemistry*; D000704:Analysis of Variance; D000818:Animals; D017610:Calcium Compounds / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry*; D004338:Drug Combinations; D010087:Oxides / Q000737:chemistry*; D010895:Pit and Fissure Sealants / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D017640:Silicates / Q000737:chemistry*; D018709:Statistics, Nonparametric; D020390:Tooth Socket / Q000187:drug effects*
D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D010895:Pit and Fissure Sealants; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide