title: [Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens].
abstract: OBJECTIVE
  To study the chemical constituents possessing cytotoxicity activity from Elaeagnus pungens.
  
  
  METHODS
  The constituents were separated through repeated chromatographic methods and their structures were elucidated by spectral analysis.
  
  
  RESULTS
  Five compounds were isolated from the ethyl acetate ether extract of leaves of E. pungens. Their structures were elucidated as 4-hydroxybenzoic acid (1), 3, 3'-dimethoxyquercetin (2), caffeic acid methyl ester (3), methyl 3, 4-dihydroxybenzoate (4), spingic acid (5), 4-methoxylbenzoic acid (6), 3-methylkaempferol (7), kaempferol-3-O-beta-D-glucoside (8), dausosterol (9).
  
  
  CONCLUSIONS
  Compounds 1-8 were isolated from this plant for the first time.
authors.affiliation: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhao
authors.forename: Rui-Liang
authors.initials: RL
authors.lastname: Zhu
authors.forename: Biao
authors.initials: B
authors.lastname: Jiang
authors.forename: Hao
authors.initials: H
authors.lastname: Huang
mesh_terms: D002109:Caffeic Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D049109:Cell Proliferation / Q000187:drug effects; D031263:Elaeagnaceae / Q000737:chemistry*; D006367:HeLa Cells / Q000166:cytology; D006801:Humans; D044949:Kaempferols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010226:Parabens / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: C464826:3-methylkaempferol; D002109:Caffeic Acids; D044949:Kaempferols; D010226:Parabens; C060385:3,3'-di-O-methylquercetin; D011794:Quercetin; C038193:4-hydroxybenzoic acid; C497945:caffeic acid methyl ester