Coronavirus phylogeny based on 2D graphical representation of DNA sequence.
A novel coronavirus has been identified as the cause of the outbreak of severe acute respiratory syndrome (SARS). Previous phylogenetic analyses based on sequence alignments show that SARS-CoVs form a new group distantly related to the other three groups of previously characterized coronaviruses. In this aritcle, a new approach based on the 2D graphical representation of the whole genome sequence is proposed to analyze the phylogenetic relationships of coronaviruses. The evolutionary distances are obtained through measuring the differences among the two-dimensional curves.
Liao
Bo
B
Laboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan 410082, People's Republic of China. dragonbw@163.com
Xiang
Xuyu
X
Zhu
Wen
W
D000818:Animals; D001483:Base Sequence; D017934:Coronavirus / Q000145:classification* / Q000235:genetics*; D004247:DNA / Q000032:analysis* / Q000235:genetics*; D016679:Genome, Viral / Q000235:genetics; D002679:Pan troglodytes / Q000235:genetics; D010802:Phylogeny
D004247:DNA