[Renal cell renal carcinoma. Analysis of incidence and survival in a 90.000 citizens healthcare area].
OBJECTIVE
To evaluate the most relevant epidemiological and survival data of the renal cell carcinoma (RCC) in a 90.000 citizens geographic area, as well as its association with risk factors such as tobacco or diuretic drugs use.


METHODS
All patients with the pathologic diagnosis of renal cell carcinoma between January 1st 1987 and January 31st 2004 were included in the study. Adjusted incidence rates (standardized) per 100.000 inhabitants year, annual percentage increase, and epidemic index in the health-care area VIII in Ciudad Real (90.000 inhabitants) were calculated. For the population adjustment we used the data Published by the National Institute of Statistics. We evaluated the differences in mortality between males/females, as well as in relation to tobacco consumption, using the chi-square test or the Fisher exact test, and the overall survival by a Cox regression model.


RESULTS
Thirty-eight RCC were diagnosed, with a maximum incidence of 7.21 cases per 100.000 inhabitants year. There was an annual percentage increase of 2.06% over the whole period. There were no statistically significant differences in gender-associated mortality (p = 0.1), tumor stage (p = 0.063), tobacco consumption (p = 0.13), diuretic drugs consumption (p = 0.69), or both (p = 0.5). Mortality was significantly higher during the first 5 years after surgery.


CONCLUSIONS
The incidence of RCC is progressively increasing, and it is predictable that this trend will be maintained in the next years. Overall mortality (any cause) associated with RCC is higher in the first five years after diagnosis.
Santos Arrontes
Daniel
D
Servicio de Urología, Hospital Santa Bárbara, Puertollano, Ciudad Real, España. danielsantosarrontes@yahoo.es
de Castro Barbosa
Fernando
F
Valer López-Fando
María Paz
MP
Fernández Arjona
Manuel
M
Cortés Aránguez
Ignacio
I
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology*; D002391:Catchment Area, Health; D005260:Female; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000453:epidemiology*; D008297:Male; D012189:Retrospective Studies; D015996:Survival Rate