title: [Links between periodontal disease and general health. 1. Pneumonia and cardiovascular disease].
abstract: The possible link between oral and general health is based on an old concept. This paper summarizes current ideas on the role of translocation of oral pathogens to other parts of the body in the development of systemic disease. It appears that colonisation of the oral cavity by respiratory pathogens is a risk factor in the development of pneumonia in institutionalised elderly and intensive care patients. Using a chloorhexidine oral rinse may reduce the risk of pneumonia. Furthermore, periodontal disease is associated with an increased risk of cardiovascular disease. Translocation of oral microorganisms and an increase in serum concentrations of inflammatory mediators are considered to play a role in the development of cardiovascular disease. Potentially, preventive oral health care and periodontal intervention could play a part in preventing cardiovascular disease.
authors.affiliation: Afdeling Kaakchirurgie van het Universitair Medisch Centrum Groningen. w.nesse@kchir.umcg.nl
authors.forename: W
authors.initials: W
authors.lastname: Nesse
authors.forename: F K L
authors.initials: FK
authors.lastname: Spijkervet
authors.forename: F
authors.initials: F
authors.lastname: Abbas
authors.forename: A
authors.initials: A
authors.lastname: Vissink
mesh_terms: D018988:Bacterial Translocation; D002318:Cardiovascular Diseases / Q000209:etiology*; D006801:Humans; D009055:Mouth / Q000382:microbiology*; D009909:Oral Health; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000150:complications*; D011014:Pneumonia / Q000209:etiology*; D018410:Pneumonia, Bacterial / Q000209:etiology