title: Anesthesia following overfilling of a root canal sealer into the mandibular canal: a case report.
abstract: The surgical treatment of a case of anesthesia that occurred with the extrusion of Endomethasone root canal sealer into the mandibular canal is presented. Endomethasone is a neurotoxic root canal sealer containing paraformaldehyde and eugenol. The literature indicates immediate surgical decompression on the extrusion of Endomethasone into the mandibular canal. In our case, the decompression surgery was done 3 weeks after the endodontic mishap. The nearly complete resolution of anesthesia 4 months following the decompression surgery suggests that the neurotoxic effects of Endomethasone are still reversible after 3 weeks.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Istanbul University, Turkey. banugr@e-kolay.net
authors.forename: Banu Gürkan
authors.initials: BG
authors.lastname: Köseoğlu
authors.forename: Sinasi
authors.initials: S
authors.lastname: Tanrikulu
authors.forename: Rüstem Kemal
authors.initials: RK
authors.lastname: Sübay
authors.forename: Serra
authors.initials: S
authors.lastname: Sencer
mesh_terms: D000328:Adult; D019299:Decompression, Surgical; D003907:Dexamethasone / Q000009:adverse effects*; D004338:Drug Combinations; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications*; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects*; D006987:Hypesthesia / Q000139:chemically induced* / Q000601:surgery; D008340:Mandibular Nerve / Q000187:drug effects*; D012387:Root Canal Filling Materials / Q000009:adverse effects*; D012389:Root Canal Obturation / Q000009:adverse effects*; D013943:Thymol / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D004338:Drug Combinations; D012387:Root Canal Filling Materials; C011244:corticosteroid methanetriol mixture; D005557:Formaldehyde; D013943:Thymol; D003907:Dexamethasone; D006854:Hydrocortisone