Acute paralysis following recreational MDMA (Ecstasy) use.
Methylenedioxymethamphetamine (MDMA), commonly known as Ecstasy, is a hallucinogenic compound structurally related to amphetamine. Ecstasy's severe neurological toxicity includes seizures, subarachnoidal hemorrhage, cerebral infarction, intracranial bleeding and cerebral venous thrombosis. We describe the first case of spinal cord damage presenting as acute quadriplegia and respiratory insufficiency in a healthy adolescent following Ecstasy recreational usage.
Goldstein
Lee H
LH
Clinical Pharmacology and Toxicology Unit, Assaf Harofeh Medical Center, Tel Aviv University, Zerifin, Israel.
Mordish
Yair
Y
Abu-Kishak
Ibrahim
I
Toledano
Michal
M
Berkovitch
Matitiahu
M
D000208:Acute Disease; D000293:Adolescent; D006213:Hallucinogens / Q000506:poisoning* / Q000652:urine; D006801:Humans; D008297:Male; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000506:poisoning* / Q000652:urine; D011782:Quadriplegia / Q000139:chemically induced* / Q000628:therapy; D012131:Respiratory Insufficiency / Q000139:chemically induced / Q000628:therapy; D016896:Treatment Outcome
D006213:Hallucinogens; D018817:N-Methyl-3,4-methylenedioxyamphetamine