title: Functional outcome after gamma knife treatment in vestibular schwannoma.
abstract: Radiosurgery (RS) is a noninvasive, ambulatory special neurosurgical procedure for the treatment of vestibular schwannoma (VS). We treated 123 patients with unilateral schwannomas between 1994 and 2000 at the gamma knife (GK) center in Munich using a primary stereotactic procedure. These patients were followed up until June 2004 in respect to audiological, neurological, neurootological and radiological features before and after radiosurgical intervention. The actual tumor control rate of 8.2 years (mean) after GK surgery for all patients and a single treatment was calculated to be 96.7%. The impairment of hearing was on average 18% after GK, ranking from 0% gain of hearing loss up to 90%. Facial nerve function, graded according to the House-Brackmann scale, deteriorated in none of the patients; 5.8% reported a trigeminal neuralgia. Tinnitus developed in 4.1% of the patients after RS; 13.3% had vertigo for the first time after the treatment, age apparently being a predisposing factor. Radiosurgical treatment for VS is an alternative to microsurgery (MS). It is associated with a lower rate of facial and trigeminal neuropathy, postoperative complications and hospital stay. The hearing preservation rate is equivalent to MS.
authors.affiliation: Department of ENT, Head and Neck Surgery, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany. John-Martin.Hempel@med.uni-muenchen.de
authors.forename: J M
authors.initials: JM
authors.lastname: Hempel
authors.forename: E
authors.initials: E
authors.lastname: Hempel
authors.forename: B
authors.initials: B
authors.lastname: Wowra
authors.forename: Ch
authors.initials: Ch
authors.lastname: Schichor
authors.forename: A
authors.initials: A
authors.lastname: Muacevic
authors.forename: A
authors.initials: A
authors.lastname: Riederer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D020220:Facial Nerve Injuries; D005260:Female; D005500:Follow-Up Studies; D034381:Hearing Loss; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications; D016634:Radiosurgery / Q000379:methods*; D012189:Retrospective Studies; D014012:Tinnitus; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000503:physiopathology; D061221:Trigeminal Nerve Injuries; D014277:Trigeminal Neuralgia / Q000209:etiology / Q000503:physiopathology; D014717:Vertigo