title: Changes in the 3-dimensional distribution of mitochondria during meiotic divisions of mouse oocytes.
abstract: Mitochondrial reorganization during meiotic maturation and parthenogenetic activation was studied in mouse oocytes using a laser scanning confocal microscope and a transmission electron microscope. Mitochondria were mainly distributed perinuclearly in the germinal vesicle (GV) stage oocytes and were dispersed throughout ooplasm after germinal vesicle breakdown (GVBD), except for a slightly higher occurrence in one hemisphere of oocytes, from which the first polar body (PbI) would become extruded. Mitochondria reaggregated around the metaphae II (MII) spindle and pronuclear region after alcohol activatation at the MII stage. The mitochondrial distribution may correspond to the Ca(2+) changes during meiotic maturation and parthenogenetic activation.
authors.affiliation: Biology Department of Nanjing Normal University, Nanjing 210097, China.
authors.forename: C J
authors.initials: CJ
authors.lastname: Li
authors.forename: B Q
authors.initials: BQ
authors.lastname: Fan