title: The formation of 1-dimethylaminonaphthalene-5-sulphonamide during the preparation of 1-dimethylaminonaphthalene-5-sulphonylamino acids.
abstract: 1. The amount of 1-dimethylaminonaphthalene-5-sulphonamide formed during the reaction of an amino acid with 1-dimethylaminonaphthalene-5-sulphonyl chloride depends on the structure of the amino acid and on the conditions used. 2. The reaction probably involves attack of a further molecule of 1-dimethylaminonaphthalene-5-sulphonyl chloride on the 1-dimethylaminonaphthalene-5-sulphonyl-amino acid and also gives the aldehyde (or ketone) with one carbon atom less than the parent amino acid.
authors.affiliation: Medical Research Council Unit for Research on the Chemical Pathology of Mental Disorders, Department of Physiology, The Medical School, Birmingham 15.
authors.forename: D J
authors.initials: DJ
authors.lastname: Neadle
authors.forename: R J
authors.initials: RJ
authors.lastname: Pollitt