title: Pulmonary nocardiosis: an unusual cause of a solitary pulmonary nodule.
abstract: Nocardiosis is an infection caused by a soil-borne aerobic micro-organism. The pathogen is most commonly introduced in humans by inhalation into the respiratory tract. This infection may be transient and subclinical or may result in an acute or chronic bronchopulmonary process. Although an unusual cause of pulmonary infection in immunocompentent individuals, human nocardiosis is now documented more often in patients whose cell-mediated immunity is compromised by immunosuppression from comorbid disease or as a result of modern medical intervention. The diagnosis is often elusive unless a high index of suspicion is maintained. We present a patient with localized pulmonary nocardiosis who was immunosuppressed by virtue of a myeloproliferative disorder.
authors.affiliation: Division of Pulmonary Diseases and Critical Care Medicine, Veterans Affairs Medical Center, Mountain Home, TN 37684-4000, USA.
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Shaikh
authors.forename: Ryland P
authors.initials: RP
authors.lastname: Byrd
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Roy
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001707:Biopsy, Needle; D001999:Bronchoscopy; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D008297:Male; D009436:Neural Tube Defects / Q000150:complications / Q000188:drug therapy; D009617:Nocardia Infections / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D009616:Nocardia asteroides / Q000302:isolation & purification; D055728:Primary Myelofibrosis / Q000150:complications / Q000188:drug therapy; D013902:Radiography, Thoracic; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis / Q000209:etiology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination