[Perspective of cutaneous lymphoma reserach].
Primary cutaneous lymphomas are characterized by an expansion of hematopoietic cells in the special microenvironment of the skin. They represent a special challenge both for researches and for clinicians who treat patients with these disorders. New research data concerning the biology of lymphocytes and the cutaneous microenvironment have increased our knowledge of these diseases in the last decades. The new WHO/EORTC classification definitely will facilitate a more detailed investigation of the various subtypes.
Dummer
Reinhard
R
Dermatologische Klinik, UniversitätsSpital Zürich, Schweiz. reinhard.dummer@usz.ch
Urosevic
Mirjana
M
Cozzio
Antonio
A
Asagoe
Kenji
K
Döbbeling
Udo
U
Burg
Günter
G
D035843:Biomedical Research; D015704:CD4 Antigens / Q000032:analysis; D019002:CD56 Antigen / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003713:Dendritic Cells / Q000473:pathology; D006413:Hematopoietic System / Q000473:pathology; D006801:Humans; D053650:Interleukin-3 Receptor alpha Subunit; D037181:Lectins, C-Type / Q000032:analysis; D016393:Lymphoma, B-Cell / Q000145:classification / Q000473:pathology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000145:classification / Q000473:pathology*; D008562:Membrane Glycoproteins / Q000032:analysis; D010950:Plasma Cells / Q000473:pathology; D011971:Receptors, Immunologic / Q000032:analysis; D016185:Receptors, Interleukin-3 / Q000032:analysis; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification / Q000473:pathology*
D015704:CD4 Antigens; D019002:CD56 Antigen; C443299:CLEC4C protein, human; C115022:IL3RA protein, human; D053650:Interleukin-3 Receptor alpha Subunit; D037181:Lectins, C-Type; D008562:Membrane Glycoproteins; D011971:Receptors, Immunologic; D016185:Receptors, Interleukin-3