Hyphenation of infrared spectroscopy to liquid chromatography for qualitative and quantitative polymer analysis: degradation of poly(bisphenol A)carbonate.
Hyphenation of infrared spectroscopy (IR) to liquid chromatography (LC) has been applied to study chemical changes in poly(bisphenol A)carbonate (PC) as a result of degradation. Especially coupling of LC to FTIR through solvent elimination is a sensitive approach to identify changes in functionality observed in the LC chromatograms as has been demonstrated by coupling of liquid chromatography under critical conditions (LCCC) to IR. Furthermore, an example is shown in which two-dimensional liquid chromatography, i.e. LCCC x SEC, was coupled to IR by means of a flow cell. This resulted in data sets containing most probably valuable data, but extracting relevant information from these large data sets is not straightforward at all. Therefore, multivariate data analysis (MVDA) of SEC-FTIR data was used to extract relevant data from large data sets. This approach revealed chemical differences due to degradation that could not be detected by other means. Spectral features could be identified that allowed to quantitatively predict the degradation of poly(bisphenol A)carbonate as a function of degradation conditions.
Coulier
Leon
L
Packaging Research and Polymer Analysis Group, Analytical Sciences Department, TNO Quality of Life, Utrechtseweg 48, 3704 HE Zeist, The Netherlands. coulier@voeding.tno.nl
Kaal
Erwin
E
Hankemeier
Thomas
T
D001559:Benzhydryl Compounds; D002853:Chromatography, Liquid / Q000295:instrumentation* / Q000379:methods*; D015999:Multivariate Analysis; D011108:Polymers / Q000032:analysis* / Q000378:metabolism*; D013055:Spectrophotometry, Infrared / Q000379:methods*; D000098826:Bisphenol A Compounds; D000098827:Polycarbonates
D001559:Benzhydryl Compounds; D011108:Polymers; C028237:bisphenol-A-polycarbonate; D000098826:Bisphenol A Compounds; D000098827:Polycarbonates