Fast flies take a quantum leap.
Presynaptic regulation of quantal size is an appealing mechanism for changing synapse strength. In this issue of Neuron, Steinert et al. describe an activity-dependent increase in synapse strength mediated by the formation and release of large synaptic vesicles at the Drosophila neuromuscular junction.
Daniels
Richard W
RW
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
DiAntonio
Aaron
A
D000818:Animals; D004330:Drosophila / Q000502:physiology*; D008124:Locomotion / Q000502:physiology; D009469:Neuromuscular Junction / Q000502:physiology*; D017729:Presynaptic Terminals / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*; D013572:Synaptic Vesicles / Q000502:physiology*