title: Evaluation of GafChromic EBT prototype B for external beam dose verification.
abstract: The capability of the new GafChromic EBT prototype B for external beam dose verification is investigated in this paper. First the general characteristics of this film (dose response, postirradiation coloration, influence of calibration field size) were derived using a flat-bed scanner. In the dose range from 0.1 to 8 Gy, the sensitivity of the EBT prototype B film is ten times higher than the response of the GafChromic HS, which so far was the GafChromic film with the highest sensitivity. Compared with the Kodak EDR2 film, the response of the EBT is higher by a factor of 3 in the dose range from 0.1 to 8 Gy. The GafChromic EBT almost does not show a temporal growth of the optical density and there is no influence of the chosen calibration field size on the dose response curve obtained from this data. A MatLab program was written to evaluate the two-dimensional dose distributions from treatment planning systems and GafChromic EBT film measurements. Verification of external beam therapy (SRT, IMRT) using the above-mentioned approach resulted in very small differences between the planned and the applied dose. The GafChromic EBT prototype B together with the flat-bed scanner and MatLab is a successful approach for making the advantages of the GafChromic films applicable for verification of external beam therapy.
authors.affiliation: Department of Radiotherapy and Radio-Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. todorovic@uke.uni-hamburg.de
authors.forename: M
authors.initials: M
authors.lastname: Todorovic
authors.forename: M
authors.initials: M
authors.lastname: Fischer
authors.forename: F
authors.initials: F
authors.lastname: Cremers
authors.forename: E
authors.initials: E
authors.lastname: Thom
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
mesh_terms: D002138:Calibration; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D005858:Germany; D011785:Quality Assurance, Health Care / Q000379:methods* / Q000592:standards*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000592:standards*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity