title: Both bronchial and vascular stenting followed by chemoradiotherapy for locally advanced non-small cell lung cancer.
abstract: Airway and vascular constrictions are expected problems for lung cancer patients. The clinical course of a patient in whom stents were inserted in 3 constriction regions is reported. A 72-year-old man with advanced primary lung cancer (squamous cell carcinoma stage IIIB) developed suffocating constriction of the trachea and showed superior vena cava (SVC) syndrome. Self-expandable metal stents were inserted into the trachea, SVC and left subclavian vein and the patient was treated by radiotherapy and weekly irinotecan. Within 5 months of treatment, complete local control was achieved and there was no reconstriction. Both endobronchial and endovascular stenting prior to antitumor therapy may be beneficial in the treatment of locally advanced cases of lung cancer.
authors.affiliation: Division of Respiratory Diseases, Department of Medicine and Kawasaki Medical School, Okayama, Japan. mifukuda258@nifty.com
authors.forename: Minoru
authors.initials: M
authors.lastname: Fukuda
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Obase
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miyashita
authors.forename: Dai
authors.initials: D
authors.lastname: Shibata
authors.forename: Kenji
authors.initials: K
authors.lastname: Yoshida
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Mori
authors.forename: Keiji
authors.initials: K
authors.lastname: Mouri
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kobashi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Niki
authors.forename: Mikio
authors.initials: M
authors.lastname: Oka
mesh_terms: D000368:Aged; D002166:Camptothecin / Q000031:analogs & derivatives / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D000077146:Irinotecan; D008175:Lung Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D015607:Stents; D013479:Superior Vena Cava Syndrome / Q000209:etiology / Q000601:surgery*; D014135:Tracheal Stenosis / Q000209:etiology / Q000601:surgery*
chemical_list: D000077146:Irinotecan; D002166:Camptothecin