title: AA amyloidosis complicating hyperimmunoglobulinemia D with periodic fever syndrome: a report of two cases.
abstract: AA amyloidosis is the most serious potential complication of the inherited autoinflammatory syndromes and frequently results in end-stage renal failure. Although this complication is well recognized in familial Mediterranean fever, tumor necrosis factor receptor-associated periodic syndrome, and Muckle-Wells syndrome, there is only 1 previous published report of its occurrence in hyperimmunoglobulinemia D with periodic fever syndrome (HIDS). We report 2 further cases of patients with AA amyloidosis in HIDS, both of whom developed dialysis-dependent renal failure, and we describe the outcome of the first renal transplant in this setting.
authors.affiliation: Royal Free and University College Medical School, London, UK. h.lachmann@medsch.ucl.ac.uk
authors.forename: Helen J
authors.initials: HJ
authors.lastname: Lachmann
authors.forename: Hugh J B
authors.initials: HJ
authors.lastname: Goodman
authors.forename: Peter A
authors.initials: PA
authors.lastname: Andrews
authors.forename: Hugh
authors.initials: H
authors.lastname: Gallagher
authors.forename: James
authors.initials: J
authors.lastname: Marsh
authors.forename: Stephan
authors.initials: S
authors.lastname: Breuer
authors.forename: Dorota M
authors.initials: DM
authors.lastname: Rowczenio
authors.forename: Alison
authors.initials: A
authors.lastname: Bybee
authors.forename: Philip N
authors.initials: PN
authors.lastname: Hawkins
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications*; D010505:Familial Mediterranean Fever / Q000150:complications*; D006801:Humans; D007072:Immunoglobulin D / Q000097:blood*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D000685:Serum Amyloid A Protein
chemical_list: D007072:Immunoglobulin D; D000685:Serum Amyloid A Protein