Synthesis and chemistry of enantiomerically pure 10,11-dihydrodibenzo[b,f]thiepines.
Several chiral thiepines were efficiently constructed using sulfur diimidazole in combination with a variety of bislithiated carbon fragments. The sulfur atom in these thiepines is found to be unusually unreactive compared to diphenylsulfide.
Wyatt
Paul
P
School of Chemistry, Cantock's Close, Bristol BS8 1TS, UK.
Hudson
Andrew
A
Charmant
Jonathan
J
Orpen
A Guy
AG
Phetmung
Hirihattaya
H
D018360:Crystallography, X-Ray; D003988:Dibenzothiepins / Q000138:chemical synthesis* / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry; D018020:Lithium Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism; D013455:Sulfur / Q000737:chemistry
D003988:Dibenzothiepins; D007093:Imidazoles; D018020:Lithium Compounds; D013455:Sulfur