Antimycobacterial flavonoids from Derris indica.
Flavonoids (1-4), together with ten known compounds (5-14) were isolated from the stems and roots of the mangrove plant Derris indica. Their chemical structures were elucidated by analysis of their spectroscopic data. All compounds except compounds 2 and 6 exhibited antimycobacterial activity with minimum inhibitory concentrations (MIC) between 6.25 and 200 microg/mL.
Koysomboon
Sorwaporn
S
School of Science, Walailak University, Thasala, Nakhon Si Thammarat 80160, Thailand.
van Altena
Ian
I
Kato
Shigeru
S
Chantrapromma
Kan
K
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D029866:Derris / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
D000900:Anti-Bacterial Agents; D005419:Flavonoids