title: Evaluation of the tissue response to MTA and MBPC: Microscopic analysis of implants in alveolar bone of rats.
abstract: The aim of this study was to evaluate and compare the quantitative and qualitative inflammatory responses and bone formation potential after implantation of polyethylene tubes filled with a new calcium hydroxide containing sealer (MBPc) and ProRoot mineral trioxide aggregate (MTA). There were 48 Wistar rats divided in three groups: Group I (control group) empty polyethylene tubes were implanted in the extraction site; group II and III, polyethylene tubes were implanted filled with ProRoot mineral trioxide aggregate (MTA) and MBPc, respectively. At 7, 15, and 30 days after tube implantation, the animals were killed, the hemi-maxillas were removed and prepared to light microscopic analyses. The scores obtained were submitted to Kruskal-Wallis statistical test (p < 0.05). Significant differences between the materials were not observed. The results showed that both materials had similar biological response.
authors.affiliation: Department of Endodontics of the Dentistry Faculty of the State University of Campinas, UNICAMP, Piracicaba, SP, Brazil. lucianocintra@fop.unicamp.br
authors.forename: Luciano Tavares Angelo
authors.initials: LT
authors.lastname: Cintra
authors.forename: Ivaldo Gomes
authors.initials: IG
authors.lastname: de Moraes
authors.forename: Bernabé Pedro Felício
authors.initials: BP
authors.lastname: Estrada
authors.forename: João Eduardo
authors.initials: JE
authors.lastname: Gomes-Filho
authors.forename: Clóvis Monteiro
authors.initials: CM
authors.lastname: Bramante
authors.forename: Roberto Brandão
authors.initials: RB
authors.lastname: Garcia
authors.forename: Norberti
authors.initials: N
authors.lastname: Bernardinelli
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry*; D000704:Analysis of Variance; D000818:Animals; D017610:Calcium Compounds / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry*; D004338:Drug Combinations; D010087:Oxides / Q000737:chemistry*; D010895:Pit and Fissure Sealants / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D017640:Silicates / Q000737:chemistry*; D018709:Statistics, Nonparametric; D020390:Tooth Socket / Q000187:drug effects*
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D010895:Pit and Fissure Sealants; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide