title: Carbon dioxide laser microsurgery for early glottic carcinoma.
abstract: OBJECTIVE
  To define the oncologic efficacy of transoral endoscopic CO2 laser surgery in early glottic carcinoma.
  
  
  METHODS
  A retrospective study of 103 patients with glottic carcinoma (14 Tis, 68 pT1a, 14 pT1b, and 7 pT2) treated from October 1993 to June 2001. Surgical treatment included endoscopic CO2 laser cordectomies according to the classification of the European Laryngological Society.
  
  
  RESULTS
  According to the Kaplan-Meier method, the probability of remaining free of local recurrence 5 years after primary surgery alone was 100% for the Tis, 96.05% for the T1, and 100% for the T2. Local control at 5 years after exclusive CO2 laser salvage surgery was 98.03%. The probability of remaining free of local recurrence 5 years after any type of salvage surgery was 100%. Laryngeal preservation was achieved in 100% of the cases.
  
  
  CONCLUSIONS
  According to the present series, endoscopic CO2 laser surgery is an effective treatment for early glottic cancer.
  
  
  METHODS
  C-4.
authors.affiliation: Department of Surgical Sciences and Organ Transplantations, Section of Otorhinolaryngology, University of Cagliari, Cagliari, Italy.
authors.forename: Gian Peppino
authors.initials: GP
authors.lastname: Ledda
authors.forename: Roberto
authors.initials: R
authors.lastname: Puxeddu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002245:Carbon Dioxide; D002294:Carcinoma, Squamous Cell / Q000145:classification / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005931:Glottis / Q000469:parasitology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000145:classification / Q000601:surgery*; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D002245:Carbon Dioxide