Protein degradation by the ubiquitin-proteasome pathway in normal and disease states.
Lecker
Stewart H
SH
Nephrology Division, Beth Isreal Deaconess, Harvard Medical School, Boston, Massachusetts, USA.
Goldberg
Alfred L
AL
Mitch
William E
WE
D007674:Kidney Diseases / Q000378:metabolism; D009124:Muscle Proteins / Q000378:metabolism; D009133:Muscular Atrophy / Q000503:physiopathology; D009210:Myofibrils / Q000201:enzymology; D009369:Neoplasms / Q000628:therapy; D046988:Proteasome Endopeptidase Complex / Q000276:immunology / Q000502:physiology*; D061988:Proteasome Inhibitors; D046188:Protein Modification, Translational / Q000502:physiology; D011506:Proteins / Q000378:metabolism*; D025801:Ubiquitin / Q000502:physiology*; D044764:Ubiquitin-Activating Enzymes / Q000502:physiology*
D009124:Muscle Proteins; D061988:Proteasome Inhibitors; D011506:Proteins; D025801:Ubiquitin; D046988:Proteasome Endopeptidase Complex; D044764:Ubiquitin-Activating Enzymes