title: Basal ovarian cysts and clomiphene citrate ovulation induction cycles.
abstract: OBJECTIVE
  To evaluate the effect of simple basal ovarian cysts in patients undergoing infertility treatment with clomiphene citrate. To evaluate the effect of clomiphene citrate on pretreatment simple ovarian cysts.
  
  
  METHODS
  Prospective cohort trial of 84 infertility patients undergoing ovulation induction with clomiphene citrate. Patients with basal ovarian cysts of 10 mm or greater (n = 42) were compared with patients without ovarian cysts (n = 42). The main outcome measure was ovulation determined by menstrual cycle day 21 progesterone level. Each patients with an ovarian cyst was also evaluated for persistence or resolution of the cyst in association with ovulation and cyst size. Pretreatment and posttreatment transvaginal ultrasound examinations were performed on all patients.
  
  
  RESULTS
  Demographic data were similar among the groups. The mean ovarian cyst size was 17.4 +/- 5.8 mm. Patients in the ovarian cyst group were significantly less likely to ovulate (80.9% versus 97.6%, P < .05), but did not differ in pregnancy rate compared with patients without baseline ovarian cysts (4.8% versus 11.9%, P = .43). Persistent ovarian cysts occurred in 36.7% of the patients. The initial size of the cyst did not predict cyst persistence.
  
  
  CONCLUSIONS
  According to these data, basal ovarian cysts significantly reduce ovulatory events in patients treated with clomiphene citrate.
  
  
  METHODS
  II-2.
authors.affiliation: Tripler Army Medical Center, Honolulu, Hawaii 95859-5000, USA.
authors.forename: John M
authors.initials: JM
authors.lastname: Csokmay
authors.forename: John L
authors.initials: JL
authors.lastname: Frattarelli
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use*; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D006801:Humans; D010048:Ovarian Cysts / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D010062:Ovulation Induction; D014463:Ultrasonography
chemical_list: D005300:Fertility Agents, Female; D002996:Clomiphene