The development and validation of the impact of multiple sclerosis scale and the symptoms of multiple sclerosis scale.
OBJECTIVE
To develop and validate the Impact of Multiple Sclerosis Scale (IMSS) and the Symptoms of Multiple Sclerosis Scale (SMSS) using the Extended Disability Status Scale (EDSS) for construct validity.


METHODS
Panel design involving test-retest over 4 months.


METHODS
A mailed survey.


METHODS
Volunteers with a diagnosis of multiple sclerosis (MS) recruited from an MS support service in Australia: 193 people (mean age, 39y) and 150 people participated at time 1 and time 2, respectively.


METHODS
Not applicable.


METHODS
Principal components analyses, the Cronbach alpha, and descriptive statistics for the 2 scales; correlations for construct validity with the EDSS and retest; and confirmatory factor analysis to test the stability of IMSS and SMSS components over time.


RESULTS
The IMSS yielded 5 independent and reliable components; the SMSS yielded 3 components; both component structures were stable over time. These scales showed convergent validity with the EDSS.


CONCLUSIONS
The IMSS and SMSS are psychometrically sound scales suitable for clinical and research purposes to assess the symptoms and impact of MS.
McMillan
Lindsay
L
School of Psychology, Deakin University, 221 Burwood Highway, Burwood 3125, Australia.
Moore
Kathleen A
KA
D000328:Adult; D003627:Data Interpretation, Statistical; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000503:physiopathology* / Q000523:psychology* / Q000534:rehabilitation; D011594:Psychometrics; D015203:Reproducibility of Results; D018434:Sickness Impact Profile