title: Progressive venous stasis retinopathy and open-angle glaucoma associated with primary pulmonary hypertension.
abstract: A 40-year-old woman who had primary pulmonary hypertension presented with dilated episcleral vessels, venous stasis retinopathy, and open-angle glaucoma with reflux of blood in Schlemm's canal in both eyes. Intraocular pressure was controlled with anti-glaucoma medication along with systemic treatment of congestive heart failure. However, venous stasis retinopathy progressed with subsequent development of branch retinal vein occlusion in her right eye. The stagnation of venous blood flow and elevation of venous pressure found in individuals with primary pulmonary hypertension is responsible for these intractable ocular complications.
authors.affiliation: Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea.
authors.forename: Sungjae
authors.initials: S
authors.lastname: Yang
authors.forename: Jinho
authors.initials: J
authors.lastname: Jeong
authors.forename: June-Gone
authors.initials: JG
authors.lastname: Kim
authors.forename: Young H
authors.initials: YH
authors.lastname: Yoon
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004452:Echocardiography; D005260:Female; D005451:Fluorescein Angiography; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006068:Gonioscopy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D007429:Intraocular Pressure; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012590:Sclera / Q000098:blood supply*; D014648:Varicose Veins / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014690:Venous Pressure
chemical_list: D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents