title: Membrane traffic: catching the lysosome express.
abstract: Recent work shows that specific adaptor interactions may sort receptors into distinct cohorts of clathrin-coated vesicles. These different vesicle populations deliver cargo to sorting endosomes of differing motilities and maturation rates, thereby determining the probability of receptor recycling and the duration of endosomal signaling.
authors.affiliation: Physiological Laboratory, University of Liverpool, Crown Street, Liverpool L69 3BX, UK. clague@liv.ac.uk
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Clague
authors.forename: Dean E
authors.initials: DE
authors.lastname: Hammond
mesh_terms: D001692:Biological Transport; D022163:Clathrin-Coated Vesicles / Q000378:metabolism; D011992:Endosomes / Q000378:metabolism*; D008247:Lysosomes / Q000378:metabolism*; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D011956:Receptors, Cell Surface