A simple catalytic method for the regioselective halogenation of arenes.
This paper describes a mild palladium-catalyzed method for the regioselective chlorination, bromination, and iodination of arene C-H bonds using N-halosuccinimides as oxidants. These transformations have been applied to a wide array of substrates and can provide products that are complementary to those obtained via conventional electrophilic aromatic substitution reactions. [reaction: see text]
Kalyani
Dipannita
D
University of Michigan, Department of Chemistry, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA.
Dick
Allison R
AR
Anani
Waseem Q
WQ
Sanford
Melanie S
MS
D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry*; D013237:Stereoisomerism
D006846:Hydrocarbons, Halogenated; D011084:Polycyclic Aromatic Hydrocarbons; D010165:Palladium