title: A new 5-alkenylresorcinol sch 725681 from Aspergillus sp.
abstract: A new 5-alkenylresorcinol Sch725681 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 16 and 64 microg/ml, respectively.
authors.affiliation: Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. shu-wei.yang@spcorp.com
authors.forename: Shu-Wei
authors.initials: SW
authors.lastname: Yang
authors.forename: Tze-Ming
authors.initials: TM
authors.lastname: Chan
authors.forename: Joseph
authors.initials: J
authors.lastname: Terracciano
authors.forename: David
authors.initials: D
authors.lastname: Loebenberg
authors.forename: Mahesh
authors.initials: M
authors.lastname: Patel
authors.forename: Vincent
authors.initials: V
authors.lastname: Gullo
authors.forename: Min
authors.initials: M
authors.lastname: Chu
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000378:metabolism*; D002176:Candida albicans / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D012118:Resorcinols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D012118:Resorcinols; C511080:Sch 725681