title: Electrochemical SNPs detection using an abasic site-containing DNA on a gold electrode.
abstract: An abasic site-containing DNA combined with lumiflavin allows amperometric determination of single nucleotide polymorphism through hydrogen bond-mediated nucleobase recognition in water by using abasic sites as a molecular recognition field.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Morita
authors.forename: N B
authors.initials: NB
authors.lastname: Sankaran
authors.forename: Weimin
authors.initials: W
authors.lastname: Huang
authors.forename: Takehiro
authors.initials: T
authors.lastname: Seino
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Sato
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Norio
authors.initials: N
authors.lastname: Teramae
mesh_terms: D020029:Base Pairing; D001665:Binding Sites; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D005415:Flavins / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006860:Hydrogen Bonding; D008024:Ligands; D020641:Polymorphism, Single Nucleotide; D013499:Surface Properties; D014867:Water / Q000737:chemistry
chemical_list: D005415:Flavins; D008024:Ligands; D014867:Water; C001922:lumiflavin; D006046:Gold; D004247:DNA