title: Optimization of 124I production via 124Te(p,n)124I reaction.
abstract: (124)I was produced, via (124)Te(p,n)(124)I reaction, in greater than 3.7GBq (100 mCi, EOB) amount by bombarding (124)TeO(2) targets at 24 microA current for about 8h. This was achieved by keeping the target at 37 degrees relative to the beam during irradiation, by sweeping the beam across the target and by keeping the incident energy of the proton at 14.1MeV. The time-averaged yield of our 8h run was 21.1 MBq/microAh (0.57 mCi/microAh), which was 90% of the theoretical yield calculated using thick target yield data obtained from the reported excitation function for the reaction. At the end of bombardment, the level of (125)I and (126)I impurities, co-produced with (124)I, were 0.03% and 0.007%, respectively.
authors.affiliation: Department of Nuclear Medicine, State University of New York, Buffalo, NY, USA. msajjad@buffalo.edu
authors.forename: Munawwar
authors.initials: M
authors.lastname: Sajjad
authors.forename: Erol
authors.initials: E
authors.lastname: Bars
authors.forename: H A
authors.initials: HA
authors.lastname: Nabi
mesh_terms: D007457:Iodine Radioisotopes / Q000302:isolation & purification*; D007554:Isotopes; D011876:Radionuclide Generators; D019275:Radiopharmaceuticals / Q000302:isolation & purification*; D013691:Tellurium
chemical_list: D007457:Iodine Radioisotopes; D007554:Isotopes; D019275:Radiopharmaceuticals; D013691:Tellurium