Rescue of spermatogenesis arrest in azoospermic men after long-term gonadotropin treatment.
Several studies have shown that FSH treatment can improve sperm production quantitatively and increase the spermatogonial population in oligozoospermic men with normal hormonal profiles. In this study, we describe the results of long-term gonadotropin therapy of normogonadotropic patients with nonobstructive azoospermia.
Selman
Helmy
H
Istituto Europeo Medicina della Riproduzione Abruzzese, Spatocco Hospital, Chieti, Italy. selmanha@yahoo.com
De Santo
Mariella
M
Sterzik
Karl
K
Cipollone
Giovanni
G
Aragona
Cesare
C
El-Danasouri
Imam
I
D000328:Adult; D001706:Biopsy; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage* / Q000627:therapeutic use; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D013091:Spermatogenesis / Q000187:drug effects*; D013094:Spermatozoa / Q000473:pathology
D006728:Hormones; D011994:Recombinant Proteins; D005640:Follicle Stimulating Hormone