Convenient method of synthesizing 3-ethoxycarbonyl indoles.
We have developed a convenient two-step procedure for the synthesis of 3-ethoxycarbonyl indoles from commercially available materials. The two-step procedure involves the synthesis of 2-aryl-3-hydroxypropenoic acid ester, followed by a catalytic reduction. This method is efficient, simple, and selective.
Islam
M Shahidul
MS
Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, USA.
Brennan
Courtney
C
Wang
Qinwei
Q
Hossain
M Mahmun
MM
D002384:Catalysis; D006865:Hydrogenation; D007211:Indoles / Q000138:chemical synthesis*; D008722:Methods
D007211:Indoles