title: Post-traumatic glioma: report of two cases.
abstract: We report two cases of brain glioma that developed in the scar of an old brain trauma. The first is that of a 40-year-old man who presented with severe headaches; CT and MRI showed a large mass in the right parietal region. The tumor was unresectable and surgical biopsy showed a glioblastoma multiforme. The patient had suffered a cranial trauma in a road accident 20 years previously with an intrathecal hematoma in the right parietal region. The second case concerns a 60-year-old man who, 15 years after severe head injury in a road accident, developed a glioblastoma multiforme which was localized in the scar of the brain contusion. These cases fulfill the established criteria for a traumatic origin of brain tumors and add further support to the relationship between cranial trauma and the onset of glioma. As stated by other authors, an association between head trauma and brain tumor risk cannot be ruled out and should be studied further.
authors.affiliation: Department of Oncology and Hematology, Hospital of Piacenza, Piacenza, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Anselmi
authors.forename: Daniele
authors.initials: D
authors.lastname: Vallisa
authors.forename: Raffaella
authors.initials: R
authors.lastname: Bertè
authors.forename: Carlo
authors.initials: C
authors.lastname: Vanzo
authors.forename: Luigi
authors.initials: L
authors.lastname: Cavanna
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000209:etiology*; D002921:Cicatrix / Q000150:complications / Q000209:etiology; D005909:Glioblastoma / Q000150:complications / Q000175:diagnosis* / Q000209:etiology*; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed