Chondroitin sulfate for interstitial cystitis.
(1) Chondroitin sulfate solution 2.0% is a glycosaminoglycan (GAG) replenishment therapy instilled into the bladder of GAG-deficient patients with interstitial cystitis (IC). (2) Two non-randomized, uncontrolled pilot studies report improvements in patient-reported symptoms after the use of chondroitin sulfate for one year. Prospective, randomized, head-to-head trials are needed to assess the effectiveness of this technology compared with other IC therapies. (3) The cost and demand for this technology are low, but there could be a significant impact on clinics that administer treatment, if uptake increases.
Palylyk-Colwell
E
E
D002170:Canada; D002809:Chondroitin Sulfates / Q000008:administration & dosage / Q000009:adverse effects / Q000191:economics; D003365:Costs and Cost Analysis; D018856:Cystitis, Interstitial / Q000188:drug therapy*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008297:Male
D002809:Chondroitin Sulfates