title: Insecticidal activity of synthetic amides on Spodoptera frugiperda.
abstract: The phytochemistry of the genus Piper (Piperaceae) has been widely studied due to the biological properties of amides from these plants. In this work, we have synthesized and evaluated the toxic effect of 11 amides against the fall armyworm Spodoptera frugiperda larvae. The naturally occurring piperine was also evaluated. The most active amide was N-[3-(3',4'-methylenedioxyphenyl)-2-(E)-propenoyl]piperidine with a LD50 of 1.07 microg mg(-1) larvae. This amide was also evaluated by ingestion.
authors.affiliation: Departamento de Química, Universidade Federal de São Carlos, Brazil.
authors.forename: Luciane G
authors.initials: LG
authors.lastname: Batista-Pereira
authors.forename: Thais C
authors.initials: TC
authors.lastname: Castral
authors.forename: Marina T M
authors.initials: MT
authors.lastname: da Silva
authors.forename: Bruna R
authors.initials: BR
authors.lastname: Amaral
authors.forename: João B
authors.initials: JB
authors.lastname: Fernandes
authors.forename: Paulo C
authors.initials: PC
authors.lastname: Vieira
authors.forename: M Fatima G F
authors.initials: MF
authors.lastname: da Silva
authors.forename: Arlene G
authors.initials: AG
authors.lastname: Corrêa
mesh_terms: D000577:Amides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007814:Larva / Q000187:drug effects / Q000254:growth & development*; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification; D011679:Pupa / Q000187:drug effects; D018411:Spodoptera / Q000187:drug effects / Q000254:growth & development*
chemical_list: D000577:Amides; D007306:Insecticides; D010880:Piperidines