title: The enzymic reduction of nicotinamide-adenine dinucleotide by 2-mercaptoethanol.
abstract: 1. The reduction of NAD(+), by an enzyme preparation from rat liver, in the presence of 2-mercaptoethanol is reported. 2. It is suggested that the NAD(+)-linked alcohol dehydrogenase in the extract transfers hydrogen from 2-mercaptoethanol to NAD(+). 3. Both yeast and horse-liver alcohol dehydrogenases were observed to reduce NAD(+) in the presence of 2-mercaptoethanol. 4. Some interactions of 2-mercaptoethanol, cysteine or hydroxylamine with the alcohol dehydrogenases from rat liver, horse liver and yeast are discussed.
authors.affiliation: The Research Department, The Marie Curie Memorial Foundation, Caterham, Surrey.
authors.forename: R F
authors.initials: RF
authors.lastname: Lambe
authors.forename: D C
authors.initials: DC
authors.lastname: Williams