Evaluation of a unique bovine collagen matrix for soft tissue repair and reinforcement.
Veritas Collagen Matrix, a product of Synovis Surgical Innovations, is derived from bovine pericardium. It can be used for a number of applications including body wall repair and replacement. In this study, we evaluated its efficacy as an adhesion barrier in a rabbit model of uterine horn surgery. When Veritas was placed on the uterine horn stump it reduced the incidence of adhesions by 50% (n.s.) compared with untreated controls. Histologic analysis of recovered material showed that the surface was covered with a monolayer of mesothelial-like cells. In addition, there was an infiltration of host cells into the matrix of the product, which suggests a replacement of the material with host tissue.
Connolly
Raymond J
RJ
Department of Surgery, Tufts-New England Medical Center, Boston, MA 02111, USA. rconnolly@tufts-nemc.org
D000818:Animals; D001672:Biocompatible Materials; D040761:Biomimetic Materials; D002417:Cattle; D003094:Collagen; D005260:Female; D011817:Rabbits; D017695:Soft Tissue Injuries / Q000473:pathology / Q000601:surgery*; D000267:Tissue Adhesions / Q000517:prevention & control
D001672:Biocompatible Materials; D003094:Collagen