Regulators of kinesin involved in polarized trafficking and axon outgrowth.
Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.
Luo
Shuo
S
Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S, Euclid Avenue, Saint Louis, MO 63110, USA.
Nonet
Michael L
ML
D000818:Animals; D001369:Axons / Q000378:metabolism* / Q000502:physiology; D001692:Biological Transport / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000502:physiology*; D016547:Kinesins / Q000235:genetics / Q000378:metabolism*; D009479:Neuropeptides / Q000502:physiology; D013569:Synapses / Q000502:physiology
D029742:Caenorhabditis elegans Proteins; D009479:Neuropeptides; C105447:UNC-76 protein, C elegans; D016547:Kinesins