title: A clinical monitoring system for clozapine.
abstract: OBJECTIVE
  To describe a framework for the initiation and ongoing monitoring of patients on clozapine, and detail support materials that can be used in clinical settings, including general practice, to support this process.
  
  
  CONCLUSIONS
  A framework is described. Clozapine has a special place in the management of treatment-resistant schizophrenia. However, it has certain side-effects that require its use to be carefully evaluated on an individual patient basis, and encompass excellent documentation and discussion with all relevant parties. Comprehensive longitudinal monitoring is required.
authors.affiliation: St Vincent's Hospital, Fitzroy, Vic., Australia. david.castle@svhm.org.au
authors.forename: David
authors.initials: D
authors.lastname: Castle
authors.forename: Tim
authors.initials: T
authors.lastname: Lambert
authors.forename: Sue
authors.initials: S
authors.lastname: Melbourne
authors.forename: Andrew
authors.initials: A
authors.lastname: Cox
authors.forename: Gaylene
authors.initials: G
authors.lastname: Boardman
authors.forename: Katherine
authors.initials: K
authors.lastname: Fairest
authors.forename: Martin
authors.initials: M
authors.lastname: Davy
authors.forename: Joyce
authors.initials: J
authors.lastname: Goh
authors.forename: Bill
authors.initials: B
authors.lastname: Kuluris
authors.forename: Michael
authors.initials: M
authors.lastname: Berk
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003024:Clozapine / Q000009:adverse effects / Q000627:therapeutic use*; D004282:Documentation / Q000379:methods; D004347:Drug Interactions; D016903:Drug Monitoring; D004351:Drug Resistance; D006801:Humans; D008137:Longitudinal Studies; D008501:Medical Records, Problem-Oriented; D008991:Monitoring, Physiologic; D012017:Referral and Consultation; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine