title: Alternatives to CPAP in the treatment of the obstructive sleep apnea syndrome.
abstract: The obstructive sleep apnoea syndrome (OSAS) results in excessive daytime sleepiness, impaired quality of life, and is associated with an increased risk of traffic accidents and cardiovascular disease. Nasal continuous positive airway pressure (CPAP), the standard treatment for OSAS provides immediate relief of symptoms and has only minor side effects. Nevertheless, an alternative treatment is needed if CPAP is not feasible for medical or psychological reasons. Removable oral appliances that advance the mandible when fitted to the teeth during sleep also improve nocturnal breathing disturbances, symptoms, quality of life, vigilance and blood pressure in OSAS patients. Their long-term effectiveness and side effects require further study. In morbidly obese patients suffering from OSAS bariatric surgery should be considered as a treatment that reduces obesity and at the same time improves OSAS. In selected patients including those with adeno-tonsillar hypertrophy, and cranio-facial malformations various surgical techniques that enlarge the upper airway may be a treatment option for OSAS.
authors.affiliation: Pulmonary Division, Department of Internal Medicine, University Hospital of Zürich, Switzerland. pneubloc@usz.unizh.ch
authors.forename: Konrad E
authors.initials: KE
authors.lastname: Bloch
mesh_terms: D000465:Algorithms; D050110:Bariatric Surgery; D045422:Continuous Positive Airway Pressure; D006801:Humans; D019186:Mandibular Advancement; D009968:Orthodontic Appliances, Removable; D013517:Otorhinolaryngologic Surgical Procedures; D020181:Sleep Apnea, Obstructive / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*