Growth spurt hypocalcemia.
This is a clinical presentation of a healthy 12-year-old African-American male who had symptomatic hypocalcemia during a growth spurt that resolved after reaching a stable height. He had clinical findings consistent with Pseudohypoparathyroidism (PHP) with hypocalcemia, hyperphospatemia, and increased parathyroid hormone (PTH) concentration. We hypothesize that his family might have a hitherto unreported autosomal dominant PHP-Ib that may or may not be linked to the GNAS locus.
Wright
Kathryn L
KL
Division of Adolescent Medicine, Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. kwright@med.wayne.edu
Bawle
Erawati V
EV
D001827:Body Height; D002648:Child; D002657:Child Development; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology*; D008297:Male; D011547:Pseudohypoparathyroidism / Q000150:complications*