Thalamocortical connections of anterior and posterior parietal cortical areas in New World titi monkeys.
We examined the thalamocortical connections of electrophysiologically identified locations in the hand and forelimb representations in areas 3b, 1, and 5 in the New World titi monkeys (Callicebus moloch), and of area 7b/AIP. Labeled cells and terminals in the thalamus resulting from the injections were related to architectonic boundaries. As in previous studies in primates, the hand representation of area 3b has dense, restricted projections predominantly from the lateral division of the ventral posterior nucleus (VPl). Projections to area 1 were highly convergent from several thalamic nuclei including the ventral lateral nucleus (VL), anterior pulvinar (PA), VPl, and the superior division of the ventral posterior nucleus (VPs). In cortex immediately caudal to area 1, what we term area 5, thalamocortical connections were also highly convergent and predominantly from nuclei of the thalamus associated with motor, visual, or somatic processing such as VL, the medial pulvinar (PM), and PA, respectively; with moderate projections from VP, central lateral nucleus (CL), lateral posterior nucleus (LP), and VPs. Finally, thalamocortical connections of area 7b/AIP were from a range of nuclei including PA, PM, LP/LD, VL, CL, PL, and CM. The current data support two conclusions drawn from previous studies in titi monkeys and other primates. First, cortex caudal to area 1 in New World monkeys is more like area 5 than area 2. Second, the presence of thalamic input to area 5 from both motor nuclei and somatosensory nuclei of the thalamus, suggests that area 5 could be considered a highly specialized sensorimotor area.
Padberg
Jeffrey
J
Center for Neuroscience and Department of Psychology, University of California-Davis, Davis, California 95616, USA.
Krubitzer
Leah
L
D000818:Animals; D001931:Brain Mapping; D002427:Cebidae / Q000033:anatomy & histology* / Q000502:physiology; D002520:Cercopithecidae / Q000033:anatomy & histology / Q000502:physiology; D005552:Forelimb / Q000294:innervation / Q000502:physiology; D006225:Hand / Q000294:innervation / Q000502:physiology; D009434:Neural Pathways / Q000166:cytology* / Q000502:physiology; D010296:Parietal Lobe / Q000166:cytology* / Q000502:physiology; D013003:Somatosensory Cortex / Q000166:cytology / Q000502:physiology; D013788:Thalamus / Q000166:cytology* / Q000502:physiology