title: Iodine as a catalyst for efficient conversion of ketones to gem-dihydroperoxides by aqueous hydrogen peroxide.
abstract: Iodine has been shown to be an efficient catalyst for the selective dihydroperoxidation of ketones with aqueous hydrogen peroxide. Ketones were directly converted to their corresponding gem-dihydroperoxides using a "green" oxidant (30% aq H(2)O(2)) and a simple catalyst (iodine) under neutral conditions in acetonitrile. The yield of hydroperoxidation of various cyclic ketones was 60-98% including androstane-3,17-dione, and acyclic ketones were converted with a similar efficiency. [reaction: see text]
authors.affiliation: Laboratory of Organic and Bioorganic Chemistry, Jozef Stefan Institute, Jamova 39, Ljubljana, Slovenia.
authors.forename: Katja
authors.initials: K
authors.lastname: Zmitek
authors.forename: Marko
authors.initials: M
authors.lastname: Zupan
authors.forename: Stojan
authors.initials: S
authors.lastname: Stavber
authors.forename: Jernej
authors.initials: J
authors.lastname: Iskra