title: Cellulose acetate containing toluidine blue and rose bengal is an effective antimicrobial coating when exposed to white light.
abstract: Simple methods of reducing the microbial load on surfaces in hospitals are needed to reduce the risk of hospital-associated infections. Here we report on the ability of a cellulose acetate coating containing the photosensitizers toluidine blue and rose bengal to kill microbes (Staphylococcus aureus, Escherichia coli, Clostridium difficile, a bacteriophage, and Candida albicans) on its surface when illuminated with white light.
authors.affiliation: Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, United Kingdom.
authors.forename: Valérie
authors.initials: V
authors.lastname: Decraene
authors.forename: Jonathan
authors.initials: J
authors.lastname: Pratten
authors.forename: Michael
authors.initials: M
authors.lastname: Wilson
mesh_terms: D000890:Anti-Infective Agents; D002175:Candida / Q000187:drug effects; D002482:Cellulose / Q000031:analogs & derivatives* / Q000032:analysis / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D008027:Light; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D012395:Rose Bengal / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014048:Tolonium Chloride / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects
chemical_list: D000890:Anti-Infective Agents; D014048:Tolonium Chloride; D012395:Rose Bengal; C005062:acetylcellulose; D002482:Cellulose