title: Effects of penconazole on two yeast strains: growth kinetics and molecular studies.
abstract: The aim of this study consisted to evaluate the impact of a pesticide (penconazole) on the growth kinetics and genotoxicity on two yeast strains (Saccharomyces cerevisiae and Metschnikowia pulcherrima). When the penconazole was added at different phases of the growth of M. pulcherrima, no effect was noticed on the kinetics of yeast growth but DNA adducts were observed when penconazole was added in the exponential phase. Increasing doses (1-15 maximum residue limit) of the pesticide added at the beginning of the fermentation did not induce DNA adducts while kinetics were affected.
authors.affiliation: Fanar Laboratory, Lebanese Agricultural Research Institute, Beirut, Lebanon. dalal.jawich@usj.edu.lb
authors.forename: Dalal
authors.initials: D
authors.lastname: Jawich
authors.forename: Roger
authors.initials: R
authors.lastname: Lteif
authors.forename: Annie
authors.initials: A
authors.lastname: Pfohl-Leszkowicz
authors.forename: Pierre
authors.initials: P
authors.lastname: Strehaiano
mesh_terms: D018736:DNA Adducts / Q000032:analysis; D005285:Fermentation; D007700:Kinetics; D009153:Mutagens / Q000494:pharmacology; D010575:Pesticides / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D004718:Saccharomycetales / Q000187:drug effects* / Q000254:growth & development; D014230:Triazoles / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D018736:DNA Adducts; D009153:Mutagens; D010575:Pesticides; D014230:Triazoles; C087058:penconazole