title: ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data.
abstract: CONCLUSIONS
  We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression.
  
  
  BACKGROUND
  ACE-it is freely available at http://ibivu.cs.vu.nl/programs/acewww/.
authors.affiliation: Department of Mathematics, Vrije Universiteit De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands.
authors.forename: Wessel N
authors.initials: WN
authors.lastname: van Wieringen
authors.forename: Jeroen A M
authors.initials: JA
authors.lastname: Belien
authors.forename: Sjoerd J
authors.initials: SJ
authors.lastname: Vosse
authors.forename: Eskeatnaf M
authors.initials: EM
authors.lastname: Achame
authors.forename: Bauke
authors.initials: B
authors.lastname: Ylstra
mesh_terms: D000465:Algorithms; D001483:Base Sequence; D002874:Chromosome Mapping / Q000379:methods*; D003198:Computer Simulation; D018628:Gene Dosage / Q000235:genetics*; D008957:Models, Genetic; D015233:Models, Statistical; D008969:Molecular Sequence Data; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D012313:RNA / Q000235:genetics*; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software; D018511:Systems Integration
chemical_list: D012313:RNA