title: Anticancer activity of tirucallane triterpenoids from Amoora dasyclada.
abstract: A new tetranortriterpene 3alpha-acetoxy-24,25,26,27-tetranortirucalla-7-ene-23(21)-lactone (3), and eleven other compounds were isolated from the twigs of Amoora dasyclada. The structure of compound 3 was identified on the basis of spectroscopic data, and the bioactive experiments of 1 and 3-5 against AGZY 83-a (human lung cancer cells) and SMMC-7721 (human liver cancer cells) are documented. Among them, compound 5 exhibited a strong activity against SMMC-7721.
authors.affiliation: Xishuangbanna Tropical Botanical Garden, the Chinese Academy of Sciences, Kunming, Yunnan, PR China.
authors.forename: Shu-Min
authors.initials: SM
authors.lastname: Yang
authors.forename: Qi-Shi
authors.initials: QS
authors.lastname: Song
authors.forename: Chen
authors.initials: C
authors.lastname: Qing
authors.forename: Da-Gang
authors.initials: DG
authors.lastname: Wu
authors.forename: Xi-Kui
authors.initials: XK
authors.lastname: Liu
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D002455:Cell Division / Q000187:drug effects; D002681:China; D008958:Models, Molecular; D010936:Plant Extracts / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity
chemical_list: D000970:Antineoplastic Agents; D010936:Plant Extracts; D014315:Triterpenes