[The blood system and the adaptation of the organism to extreme factors].
Study of hemopoesis under extremal conditions has revealed a range of new mechanisms providing the participation of the blood system in adaptive reactions, such as the reconstruction of the microcirculation bed of hemopoetic tissue; the involvement of large erythrocytes containing acid-resistant hemoglobin fractions; qualitative and quantitative changes in the content of erythroblastic islands, depending on the functional condition of macrophages; gaining of morphogenic properties by macrophages and lymphocytes; increased secretion of glycosaminoglicans, which play the role of local hemopoetic regulators, by mastocytes and adipose cells. The correlation between blood cells and angiogenesis allowed proposing a new method of creating auto prostheses for angioplasty by growing them on plastic basis implanted subcutaneously.
Iushkov
B G
BG
D000222:Adaptation, Physiological; D001773:Blood Cells / Q000473:pathology*; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D013312:Stress, Physiological / Q000097:blood* / Q000503:physiopathology