[Blood and tissue eosinophilia in patient with angioedema caused by inhibitor of angiotensin converting enzyme (ACE)--case report and a view of literature].
A case of angioedema caused by enalapril, undiagnosed for 5 years was presented. Enhanced blood and tissue eosinophilia shown in nasal smear was observed. In addition increased activity of coagulation system was shown manifested by enhance of concentration of Hageman factor and cardiolipin antibodies IgM and IgA isotype. The role of coagulation, complement and fibrinolysis systems in pathogenesis of ACE-inhibitors induced angioedema was discussed. The influence of bradykinin on activity of eosinophils was analyzed.
Panaszek
Bernard
B
Katedra i Klinika Chorób Wewnetrznych i Alergologii AM we Wrocławiu.
Barg
Wojciech
W
Małolepszy
Józef
J
Kopeć
Wacław
W
Obojski
Andrzej
A
Wytrychowski
Krzysztof
K
Chmielowicz
Beata
B
Biełous-Wilk
Anna
A
Rabski
Marek
M
Basińska
Małgorzata
M
D000368:Aged; D000799:Angioedema / Q000139:chemically induced*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D004656:Enalapril / Q000009:adverse effects*; D004802:Eosinophilia / Q000097:blood*; D006801:Humans; D008297:Male
D000806:Angiotensin-Converting Enzyme Inhibitors; D004656:Enalapril