title: Different SPECT findings before and after Capgras' syndrome in interictal psychosis.
abstract: We herein report a case of Capgras' syndrome observed in interictal psychosis in which the single-photon emission computed tomography (SPECT) findings before and after the appearance of the psychotic symptoms differed. SPECT with 99mTc-hexamethyl propyleneamine oxine (HMPAO) revealed worsening of hypoperfusion in the entire right hemisphere after onset of the psychotic symptoms. The enhanced hypoperfusion demonstrated by SPECT in the present case seems to indicate a right interhemispheric disconnection resulting in the occurrence of Capgras' syndrome.
authors.affiliation: Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Horikawa
authors.forename: Akira
authors.initials: A
authors.lastname: Monji
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Maekawa
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Onitsuka
authors.forename: Yoko
authors.initials: Y
authors.lastname: Nitazaka
authors.forename: Yoji
authors.initials: Y
authors.lastname: Hirano
authors.forename: Shougo
authors.initials: S
authors.lastname: Hirano
authors.forename: Sadayuki
authors.initials: S
authors.lastname: Hashioka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kato
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yoshida
authors.forename: Shigenobu
authors.initials: S
authors.lastname: Kanba
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002194:Capgras Syndrome / Q000188:drug therapy / Q000209:etiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D014150:Antipsychotic Agents