title: Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes.
abstract: Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted beta-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.
authors.affiliation: Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, BC, Canada, V6T 1Z1.
authors.forename: Tyler J
authors.initials: TJ
authors.lastname: Harrison
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Kozak
authors.forename: Montserrat
authors.initials: M
authors.lastname: Corbella-Pané
authors.forename: Gregory R
authors.initials: GR
authors.lastname: Dake
mesh_terms: D000588:Amines / Q000737:chemistry; D002384:Catalysis; D017612:Gold Compounds / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis*
chemical_list: D000588:Amines; D017612:Gold Compounds; D007659:Ketones; D008698:Mesylates; D011758:Pyrroles; C012077:trifluoromethanesulfonic acid