title: Pressure relieving support surfaces (PRESSURE) trial: cost effectiveness analysis.
abstract: OBJECTIVE
  To assess the cost effectiveness of alternating pressure mattresses compared with alternating pressure overlays for the prevention of pressure ulcers in patients admitted to hospital.
  
  
  METHODS
  Cost effectiveness analysis carried out alongside the pressure relieving support surfaces (PRESSURE) trial; a multicentre UK based pragmatic randomised controlled trial.
  
  
  METHODS
  11 hospitals in six UK NHS trusts.
  
  
  METHODS
  Intention to treat population comprising 1971 participants.
  
  
  METHODS
  Kaplan Meier estimates of restricted mean time to development of pressure ulcers and total costs for treatment in hospital.
  
  
  RESULTS
  Alternating pressure mattresses were associated with lower overall costs (283.6 pounds sterling per patient on average, 95% confidence interval--377.59 pounds sterling to 976.79 pounds sterling) mainly due to reduced length of stay in hospital, and greater benefits (a delay in time to ulceration of 10.64 days on average,--24.40 to 3.09). The differences in health benefits and total costs for hospital stay between alternating pressure mattresses and alternating pressure overlays were not statistically significant; however, a cost effectiveness acceptability curve indicated that on average alternating pressure mattresses compared with alternating pressure overlays were associated with an 80% probability of being cost saving.
  
  
  CONCLUSIONS
  Alternating pressure mattresses for the prevention of pressure ulcers are more likely to be cost effective and are more acceptable to patients than alternating pressure overlays.
authors.affiliation: Department of Health Sciences, University of York, York YO10 5DD.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Iglesias
authors.forename: Jane
authors.initials: J
authors.lastname: Nixon
authors.forename: Gillian
authors.initials: G
authors.lastname: Cranny
authors.forename: E Andrea
authors.initials: EA
authors.lastname: Nelson
authors.forename: Kim
authors.initials: K
authors.lastname: Hawkins
authors.forename: Angela
authors.initials: A
authors.lastname: Phillips
authors.forename: David
authors.initials: D
authors.lastname: Torgerson
authors.forename: Su
authors.initials: S
authors.lastname: Mason
authors.forename: Nicky
authors.initials: N
authors.lastname: Cullum
mesh_terms: D000328:Adult; D000368:Aged; D001512:Bedding and Linens / Q000191:economics*; D003362:Cost-Benefit Analysis; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008875:Middle Aged; D003668:Pressure Ulcer / Q000191:economics / Q000517:prevention & control*