Memory deficits in Parkinson's disease.
The purpose of this study was to investigate deficits in recognition, recall, and prospective memory among Parkinson's disease (PD) patients, and to ascertain whether task difficulty and disease severity moderate these deficits. Comparisons were made between 41 nondemented PD participants, divided into early-stage and advanced-stage groups, and 41 matched controls. PD participants exhibited deficits in recognition, recall, and prospective memory. The advanced-stage PD group produced greater deficits than the early-stage PD group in all tasks, suggesting that these deficits increase in step with overall disease severity. The results of the task difficulty manipulation provide a partial explanation for the inconsistencies in the literature concerning the existence of recognition memory deficits in PD.
Whittington
Craig J
CJ
Sub-Department of Clinical Health Psychology, University College London, London.
Podd
John
J
Stewart-Williams
Steve
S
D000368:Aged; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008297:Male; D016555:Matched-Pair Analysis; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology; D010775:Photic Stimulation; D021641:Recognition, Psychology / Q000502:physiology*; D012016:Reference Values; D012720:Severity of Illness Index; D014706:Verbal Learning / Q000502:physiology