title: A phototaxis signalling complex in Dictyostelium discoideum.
abstract: Phototaxis has been studied in a variety of organisms belonging to all three major taxonomic domains - the bacteria, the archaea and the eukarya. Dictyostelium discoideum is one of a small number of eukaryotic organisms which are amenable to studying the signalling pathways involved in phototaxis. In this study we provide evidence based on protein coimmunoprecipitation for a phototaxis signalling complex in Dictyostelium that includes the proteins RasD, filamin, ErkB, GRP125 and PKB.
authors.affiliation: Department of Microbiology, La Trobe University, Vic. 3086, Australia.
authors.forename: Esther
authors.initials: E
authors.lastname: Bandala-Sanchez
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Annesley
authors.forename: Paul R
authors.initials: PR
authors.lastname: Fisher
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D003285:Contractile Proteins / Q000235:genetics / Q000378:metabolism; D004023:Dictyostelium / Q000166:cytology / Q000502:physiology*; D048049:Extracellular Signal-Regulated MAP Kinases / Q000235:genetics / Q000378:metabolism; D064448:Filamins; D018260:Gelsolin / Q000235:genetics / Q000378:metabolism; D008027:Light; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism; D046912:Multiprotein Complexes; D011485:Protein Binding; D051057:Proto-Oncogene Proteins c-akt / Q000235:genetics / Q000378:metabolism; D015800:Protozoan Proteins / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D003285:Contractile Proteins; D064448:Filamins; D018260:Gelsolin; D008840:Microfilament Proteins; D046912:Multiprotein Complexes; D015800:Protozoan Proteins; C117419:gelsolin-related protein, 125-kDa; C424066:rasD protein, Dictyostelium; D051057:Proto-Oncogene Proteins c-akt; D048049:Extracellular Signal-Regulated MAP Kinases