title: Treatment of ranula in pediatric patients with intralesional injection of OK-432.
abstract: OBJECTIVE
  To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432.
  
  
  METHODS
  Retrospective analysis of 13 cases.
  
  
  METHODS
  Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005.
  
  
  RESULTS
  Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed.
  
  
  CONCLUSIONS
  On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
authors.forename: Heung-Man
authors.initials: HM
authors.lastname: Lee
authors.forename: Hyun-Woo
authors.initials: HW
authors.lastname: Lim
authors.forename: Hee Joon
authors.initials: HJ
authors.lastname: Kang
authors.forename: Sung-Won
authors.initials: SW
authors.lastname: Chae
authors.forename: Soon-Jae
authors.initials: SJ
authors.lastname: Hwang
authors.forename: Kwang-Yoon
authors.initials: KY
authors.lastname: Jung
authors.forename: Jeong-Soo
authors.initials: JS
authors.lastname: Woo
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D010844:Picibanil / Q000008:administration & dosage*; D011900:Ranula / Q000188:drug therapy*; D012189:Retrospective Studies; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D012597:Sclerosing Solutions; D010844:Picibanil