Sarcophytonolides E-H, cembranolides from the Hainan soft coral Sarcophyton latum.
Four new cembrane diterpenes, sarcophytonolides E-H (1-4), were isolated from the Hainan soft coral Sarcophyton latum. Their structures were elucidated by detailed spectroscopic (IR, MS, 2D NMR) analysis and by comparison with related known compounds. The absolute stereochemistry of sarcophytonolide H (4) was determined by applying the modified Mosher's method.
Jia
Rui
R
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Shanghai 201203, People's Republic of China.
Guo
Yue-Wei
YW
Mollo
Ernesto
E
Gavagnin
Margherita
M
Cimino
Guido
G
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D014407:Tumor Cells, Cultured
D004224:Diterpenes