title: Imaging of Wegener's granulomatosis.
abstract: Wegener's granulomatosis is an uncommon multisystemic disorder of unknown aetiology. It is characterized histopathologically by necrotizing granulomatous vasculitis. Most commonly this involves the upper and lower respiratory tract, with pulmonary involvement occurring at some stage of the disease in almost all patients. However, many other organ systems can also be affected including the kidneys, orbits and central nervous system. For this pictorial review, we have assessed the imaging of 155 patients over a 10-year period in order to illustrate characteristic and some of the more unusual imaging features of Wegener's granulomatosis.
authors.affiliation: Department of Imaging, Hammersmith Hospital, Imperial College Faculty of Medicine, Du Cane Road, London W12 ONN, UK. stevendallen@hotmail.co.uk
authors.forename: S D
authors.initials: SD
authors.lastname: Allen
authors.forename: C J
authors.initials: CJ
authors.lastname: Harvey
mesh_terms: D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000150:complications / Q000000981:diagnostic imaging; D002493:Central Nervous System Diseases / Q000150:complications / Q000000981:diagnostic imaging; D004427:Ear Diseases / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000000981:diagnostic imaging; D006331:Heart Diseases / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D007674:Kidney Diseases / Q000150:complications / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009668:Nose Diseases / Q000150:complications / Q000000981:diagnostic imaging; D009916:Orbital Diseases / Q000150:complications / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000150:complications / Q000000981:diagnostic imaging; D014056:Tomography, X-Ray