Geranylated phenolic constituents from the fruits of Artocarpus nobilis.
Chemical investigation of the combined dichloromethane and ethyl acetate extracts of the fruits of Artocarpus nobilis, furnished four new geranylated phenolic constituents, 2,4,4'-trihydroxy-3-[(2E)-5-methoxy-3,7-dimethylocta-2,6-dienyl]chalcone (4), 1-(3,4-dihydro-3,5-dihydroxy-2-methyl-2-(3-methyl-2-butenyl)-2H-1-benzopyran-6-yl-3-(4-hydroxyphenyl)-2(E)-propen-1-one (5), 8-geranyl-3',4',7-trihydroxyflavone (8), 3'-geranyl-4',5,7-trihydroxyflavanone (9), together with known related compounds, xanthoangelol (1), xanthoangelol B (2), 3-geranyl-2,3',4,4'-tetrahydroxychalcone (3), lespeol (6), 8-geranyl-4',7-dihydroxyflavanone (7), and isonymphaeol-B (10). Compounds 3, 8 and 10 showed strong antioxidant activity against DPPH radical by spectrophotometric method.
Jayasinghe
Lalith
L
Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka. lalith@ifs.ac.lk
Rupasinghe
G Kalinga
GK
Hara
Noriyuki
N
Fujimoto
Yoshinori
Y
D031622:Artocarpus / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry*
D010636:Phenols; D013729:Terpenes