Treatment of ranula in pediatric patients with intralesional injection of OK-432.
OBJECTIVE
To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432.


METHODS
Retrospective analysis of 13 cases.


METHODS
Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005.


RESULTS
Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed.


CONCLUSIONS
On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.
Lee
Heung-Man
HM
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Lim
Hyun-Woo
HW
Kang
Hee Joon
HJ
Chae
Sung-Won
SW
Hwang
Soon-Jae
SJ
Jung
Kwang-Yoon
KY
Woo
Jeong-Soo
JS
D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D010844:Picibanil / Q000008:administration & dosage*; D011900:Ranula / Q000188:drug therapy*; D012189:Retrospective Studies; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D016896:Treatment Outcome
D012597:Sclerosing Solutions; D010844:Picibanil