title: Dry eye after photorefractive keratectomy with adjuvant mitomycin C.
abstract: OBJECTIVE
  To report a patient with dry eye after bilateral photorefractive keratectomy (PRK) with mitomycin C treatment in one eye.
  
  
  METHODS
  A 29-year-old woman underwent PRK for moderate myopia. The left eye was randomly assigned and intraoperative topical mitomycin C was administered. The right (control) eye was treated with intraoperative corticosteroid only.
  
  
  RESULTS
  The patient developed dry eye symptoms and superficial punctuate keratopathy in the eye treated with mitomycin C. Fifteen months after surgery no improvement was noted.
  
  
  CONCLUSIONS
  Photorefractive keratectomy with mitomycin C treatment could induce or exacerbate dry eye.
authors.affiliation: Department of Ophthalmology, Institute of Vision and Optics, University of Crete, Heraklion, Greece. kymionis@med.uoc.gr
authors.forename: George D
authors.initials: GD
authors.lastname: Kymionis
authors.forename: Nikolaos S
authors.initials: NS
authors.lastname: Tsiklis
authors.forename: Harilaos
authors.initials: H
authors.lastname: Ginis
authors.forename: Vasilios F
authors.initials: VF
authors.lastname: Diakonis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Pallikaris
mesh_terms: D000328:Adult; D015352:Dry Eye Syndromes / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007432:Intraoperative Period; D054018:Lasers, Excimer; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects*; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D009883:Ophthalmic Solutions; D018903:Photorefractive Keratectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D005938:Glucocorticoids; D019384:Nucleic Acid Synthesis Inhibitors; D009883:Ophthalmic Solutions; D016685:Mitomycin