Occupational respiratory allergy to cyclamen pollen: a case report.
A case of cyclamen (Cyclamen persicum) pollen allergy is described on a flower cultivator. The diagnosis was assessed by skin test, methacoline test, nasal provocation test and RAST. SDS-PAGE and immunoblotting have shown an intense response against a 18 kDa component and a weaker one at 100 Kda. A RAST inhibition against Cupressus sempervirens and Acacia floribundia showed no identity with cyclamen. This case confirm the cyclamen allergenity, in professional exposure. The nasal challenge prove to be very useful to confirm allergic sensitizations an we emphasize the necessity of preventive measures of protection for those florists who cultivate cyclamen plants.
Ariano
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U.O.C. Medicina Interna, Ambulatorio di Allergologia ed Immunologia Clinica, A.S.L no 1, Imperiese, Italy.
Mistrello
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Panzani
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RC
D000382:Agricultural Workers' Diseases / Q000209:etiology*; D000485:Allergens / Q000009:adverse effects* / Q000302:isolation & purification; D001249:Asthma / Q000209:etiology*; D015153:Blotting, Western; D031824:Cyclamen / Q000737:chemistry / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008875:Middle Aged; D008970:Molecular Weight; D009299:Nasal Provocation Tests; D016273:Occupational Exposure; D010328:Patch Tests; D011058:Pollen / Q000009:adverse effects* / Q000737:chemistry; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology*; D012882:Skin Tests; D013045:Species Specificity
D000485:Allergens; D007073:Immunoglobulin E