title: Effect of Tamarindus indica fruits on blood pressure and lipid-profile in human model: an in vivo approach.
abstract: Fruits of Tamarindus indica were evaluated for their effects on lipid profile, systolic and diastolic blood pressure and body weight in human subjects. Dried and pulverized pulp of T. indica fruits, at a dose of 15 mg/kg body weight, was found to reduce total cholesterol level (p = 0.031) and LDL-cholesterol level (p = 0.004) to a significant extent. Though the fruits exerted no conspicuous effect on body weight and systolic blood pressure, it significantly reduced the diastolic pressure as confirmed by independent sample t-test at 5% significance level.
authors.affiliation: Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.
authors.forename: A S M Maruf
authors.initials: AS
authors.lastname: Iftekhar
authors.forename: Israt
authors.initials: I
authors.lastname: Rayhan
authors.forename: Mohiuddin Abdul
authors.initials: MA
authors.lastname: Quadir
authors.forename: Sharif
authors.initials: S
authors.lastname: Akhteruzzaman
authors.forename: Abul
authors.initials: A
authors.lastname: Hasnat
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005638:Fruit; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D029861:Tamarindus; D014280:Triglycerides / Q000097:blood
chemical_list: D008078:Cholesterol, LDL; D010936:Plant Extracts; D014280:Triglycerides; D002784:Cholesterol