title: Protein folding in a force clamp.
abstract: Kinetics of folding of a protein held in a force clamp are compared to an unconstrained folding. The comparison is made within a simple topology-based dynamical model of ubiquitin. We demonstrate that the experimentally observed variations in the end-to-end distance reflect microscopic events during folding. However, the folding scenarios in and out of the force clamp are distinct.
authors.affiliation: Institute of Physics, Polish Academy of Sciences, Aleja Lotników 32/46, 02-668 Warsaw, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Cieplak
authors.forename: P
authors.initials: P
authors.lastname: Szymczak
mesh_terms: D017510:Protein Folding; D025801:Ubiquitin
chemical_list: D025801:Ubiquitin