Therapies for psoriatic nail disease. A systematic review.
Nail involvement is common in patients with psoriasis and psoriatic arthritis, affecting 80%-90% of patients at some time. It also has significant effects on quality of life. Psoriatic nail disease can be refractory to treatment, and different features may respond variably to different therapies. The lack of standardized outcome assessments hinders the interpretation of available data. In this systematic evidence-based review of the literature, we assess various treatments for psoriatic nail disease.
Cassell
Sarah
S
Division of Rheumatology, Allergy, and Immunology, University of California at San Diego, La Jolla, California 92093-0943, USA.
Kavanaugh
Arthur F
AF
D015535:Arthritis, Psoriatic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D004358:Drug Therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009260:Nail Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D016896:Treatment Outcome