title: [Impact of a simultaneous application of anionic salts and rumen buffer on acid-base-balance and mineral metabolism in dairy cows].
abstract: In this study, the influence of simultaneous application of anionic salts (AS) and rumen buffer (RB) on the metabolism of dairy cows was examined. Eleven rumen fistulated, non-pregnant and non-lactating dairy cows received equal amounts of one AS (CaCl2 or CaSO4) and one RB (NaHCO3 or KHCO3) via rumen cannula during feeding time over a period of eight days. Before the first application of AS and RB and on day eight of the treatment period, blood, urine and rumen fluid samples were taken. The following parameters were measured: whole blood: pH, base excess, bicarbonate; serum: sodium, potassium, chloride, calcium; urine: pH, net acid base excretion, sodium, potassium, chloride, calcium; rumen fluid: pH. The changes of each parameter were compared via ANOVA. The changes in acid-base balance on day eight were very small, although significant. But p-values showed that the statistical evidence was low. The most changes occurred when NaHCO3 was fed in combination with one of the AS used. In this case a small acidogenic load was seen in blood (p < 0.05), and calcium concentrations increased slightly (p < 0.05). No alkalotic reaction could be detected when any combination of AS and RB were given to the cows. Simultaneous application of AS and RB results in a loss of effectivity of AS. Neither an adequate acidification of blood nor an activation of calcium metabolism occurred. In feed ration for cows in the last weeks of pregnancy, rumen buffer must not be fed, if anionic salts are given for prevention of parturient paresis.
authors.affiliation: Klinik für Wiederkäuer, Department für Nutztiere und Bestandsbetreuung, Veterinärmedizinische Universität Wien. Carl-Christian.Gelfert@vu-wien.ac.at
authors.forename: Carl-Christian
authors.initials: CC
authors.lastname: Gelfert
authors.forename: Simone
authors.initials: S
authors.lastname: Hauser
authors.forename: Antje
authors.initials: A
authors.lastname: Löptien
authors.forename: Nicole
authors.initials: N
authors.lastname: Montag
authors.forename: Mareike
authors.initials: M
authors.lastname: Passmann
authors.forename: Walter
authors.initials: W
authors.lastname: Baumgartner
authors.forename: Rudolf
authors.initials: R
authors.lastname: Staufenbiel
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000818:Animals; D001639:Bicarbonates / Q000008:administration & dosage / Q000494:pharmacology*; D001774:Blood Chemical Analysis; D002021:Buffers; D017610:Calcium Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D002417:Cattle / Q000378:metabolism*; D000075202:Contraindications; D003612:Dairying; D004357:Drug Synergism; D005260:Female; D006863:Hydrogen-Ion Concentration; D008903:Minerals / Q000378:metabolism*; D010319:Parturient Paresis / Q000188:drug therapy / Q000517:prevention & control; D011247:Pregnancy; D012417:Rumen / Q000737:chemistry; D044967:Serum / Q000737:chemistry; D014556:Urine / Q000737:chemistry
chemical_list: D001639:Bicarbonates; D002021:Buffers; D017610:Calcium Compounds; D008903:Minerals