title: Gamma-irradiated human skin allograft: a potential treatment modality for lower extremity ulcers.
abstract: Gamma-irradiated human skin allograft consists of epidermis and dermis. Unlike bioengineered tissues which require cold storage and timely use once received from the manufacturer, gamma-irradiated human skin allograft can be stored for as long as 24 months at room temperature. This modality is applied in a fashion similar to that of bioengineered skin grafts. In this article, we present case studies with concise reviews of the available evidence to discuss the potential use of gamma-irradiated human skin allograft on wounds in the lower extremity.
authors.affiliation: Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ, USA.
authors.forename: M Anthony
authors.initials: MA
authors.lastname: Rosales
authors.forename: Merri
authors.initials: M
authors.lastname: Bruntz
authors.forename: David G
authors.initials: DG
authors.lastname: Armstrong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016523:Foot Ulcer / Q000601:surgery; D005720:Gamma Rays / Q000627:therapeutic use*; D006801:Humans; D007871:Leg Ulcer / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000379:methods; D014184:Transplantation, Homologous; D014945:Wound Healing