title: Characterization of single nucleotide polymorphisms in sheep and their variation as evidence of selection.
abstract: The discovery of SNPs was performed using animals from eight European sheep breeds. Eleven SNPs were further characterized using about 1,700 sheep belonging to 57 breeds. A method for the identification of loci that were likely subject to selection was applied; three of the 11 SNPs lying outside the 95% confidence region of the conditional joint distribution of F(ST) and mean heterozygosity were identified as outliers.
authors.affiliation: Dipartimento di Produzioni Animali, Università della Tuscia, Viterbo, Italy. pariset@unitus.it
authors.forename: L
authors.initials: L
authors.lastname: Pariset
authors.forename: I
authors.initials: I
authors.lastname: Cappuccio
authors.forename: S
authors.initials: S
authors.lastname: Joost
authors.forename: M
authors.initials: M
authors.lastname: D'Andrea
authors.forename: D
authors.initials: D
authors.lastname: Marletta
authors.forename: P
authors.initials: P
authors.lastname: Ajmone Marsan
authors.forename: A
authors.initials: A
authors.lastname: Valentini
mesh_terms: D000818:Animals; D005260:Female; D005838:Genotype; D006579:Heterozygote; D008297:Male; D020641:Polymorphism, Single Nucleotide; D012641:Selection, Genetic; D017422:Sequence Analysis, DNA; D012756:Sheep / Q000235:genetics*