title: A comparison of covered and uncovered Wallstents for the management of distal malignant biliary obstruction.
abstract: BACKGROUND
  The efficacy and complications of covered self-expandable metal stents (SEMS) remain controversial.
  
  
  OBJECTIVE
  We conducted this study to compare the efficacies and complication rates of covered and uncovered SEMS in malignant biliary obstruction.
  
  
  METHODS
  Data on patients who underwent endoscopic retrograde biliary drainage with covered or uncovered Wallstents for the palliation of unresectable distal malignant biliary obstruction were collected. Stent patency, complications, and causes of stent occlusion were analyzed.
  
  
  METHODS
  We collected the data retrospectively.
  
  
  METHODS
  A total of 77 patients received Wallstents for unresectable distal malignant biliary obstruction.
  
  
  METHODS
  Endoscopic sphincterotomy was performed, and a Wallstent was deployed after guidewire passage. Polyurethane-covered Wallstents were used in 36 patients and uncovered Wallstents in 41 patients.
  
  
  RESULTS
  Stent migration occurred in 3 of the covered Wallstent group and in 1 of the uncovered Wallstent group. Cholecystitis occurred in 1 of the covered Wallstent group but in none of the uncovered Wallstent group. Stent occlusion occurred after a mean of 398 days in the covered group and after 319 days in the uncovered Wallstent group (P > .05). Stent patency rates were 83%, 78%, 67%, and 54% at 100, 200, 300, and 400 days, respectively, in covered group and 83%, 66%, 54%, and 36% in the uncovered group, which was not significantly different.
  
  
  CONCLUSIONS
  This study is not a prospective randomized study and sample size is not large.
  
  
  CONCLUSIONS
  Covered Wallstents are safe with acceptable complication rates. However, we found no significant difference between the stent patencies of covered and uncovered Wallstents.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul 110-744, Korea.
authors.forename: Won Jae
authors.initials: WJ
authors.lastname: Yoon
authors.forename: Jun Kyu
authors.initials: JK
authors.lastname: Lee
authors.forename: Kwang Hyuck
authors.initials: KH
authors.lastname: Lee
authors.forename: Woo Jin
authors.initials: WJ
authors.lastname: Lee
authors.forename: Ji Kon
authors.initials: JK
authors.lastname: Ryu
authors.forename: Yong-Tae
authors.initials: YT
authors.lastname: Kim
authors.forename: Yong Bum
authors.initials: YB
authors.lastname: Yoon
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications / Q000473:pathology; D017734:Bile Ducts, Extrahepatic; D018281:Cholangiocarcinoma / Q000150:complications / Q000473:pathology; D003135:Common Bile Duct / Q000473:pathology*; D003251:Constriction, Pathologic; D005260:Female; D005548:Foreign-Body Migration / Q000453:epidemiology; D006801:Humans; D041781:Jaundice, Obstructive / Q000628:therapy*; D008297:Male; D008670:Metals; D008875:Middle Aged; D010166:Palliative Care; D010190:Pancreatic Neoplasms / Q000150:complications; D011474:Prosthesis Design; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects
chemical_list: D008670:Metals