title: Leishmune vaccine: the newest tool for prevention and control of canine visceral leishmaniosis and its potential as a transmission-blocking vaccine.
abstract: Canine visceral leishmaniosis is a life-threatening disease caused by Leishmania infantum. For quite some time, specialists in leishmaniosis have tried to develop more affordable and effective control measures against this disease. In this search, the first vaccine against canine visceral leishmaniosis was recently licensed in Brazil. In the light of recent research, the Leishmune vaccine might be seen as the newest tool for prevention and control of canine visceral leishmaniosis. Moreover, the potential of the Leishmune as a transmission-blocking vaccine has recently been demonstrated, indicating its usefulness in the control of zoonotic visceral leishmaniosis.
authors.affiliation: Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Caixa Postal 7472, Avenida Professor Moraes Rego, s/n, Campus UFPE, Recife, Pernambuco, CEP, Brazil. fdt@cpqam.fiocruz.br
authors.forename: Filipe
authors.initials: F
authors.lastname: Dantas-Torres
mesh_terms: D000818:Animals; D017326:Clinical Trials, Phase III as Topic / Q000662:veterinary; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000517:prevention & control* / Q000635:transmission; D004285:Dogs; D018314:Leishmania infantum / Q000276:immunology*; D007898:Leishmaniasis, Visceral / Q000517:prevention & control / Q000635:transmission / Q000662:veterinary*; D051379:Mice; D016052:Protozoan Vaccines; D011576:Psychodidae / Q000469:parasitology*
chemical_list: D016052:Protozoan Vaccines