title: Effect of orifice plugs on periapical inflammation in dogs.
abstract: Gutta-percha (G) and sealer do not resist coronal leakage. In this study, the effect of orifice plugs using dentin-bonding/composite resin(C) or IRM on coronal leakage was evaluated in vivo. Sixty-one premolar roots in three beagle dogs were instrumented and filled with G and AH 26(S), or G alone. The coronal 2 mm was replaced with C or IRM, or left untreated. The access cavities were kept open for 8 months, the dogs were killed and the periapical regions of the roots were histologically examined. Periapical inflammation was observed in 89% of the group without plugs, but in those with plugs, the occurrence was decreased to 39% (C + G + S), 38% (IRM + G + S) and 58% (C + G), respectively. Furthermore, severe inflammation was observed in 50% of the former group but only 0 to 17% of the latter. The substantial reduction in apical periodontitis by the use of coronal plug underscores the clinical importance of providing an additional barrier to coronal leakage in comparison to that provided by gutta-percha and sealer alone.
authors.affiliation: Department of Endodontics, UNC School of Dentistry, Chapel Hill, NC 27599, USA. shizuko_yamauchi @dentistry.unc.edu
authors.forename: Shizuko
authors.initials: S
authors.lastname: Yamauchi
authors.forename: Guy
authors.initials: G
authors.lastname: Shipper
authors.forename: Thomas
authors.initials: T
authors.lastname: Buttke
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Yamauchi
authors.forename: Martin
authors.initials: M
authors.lastname: Trope
mesh_terms: D000818:Animals; D001729:Bismuth / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D003763:Dental Leakage / Q000150:complications / Q000517:prevention & control*; D004285:Dogs; D004338:Drug Combinations; D004853:Epoxy Resins / Q000627:therapeutic use*; D006171:Gutta-Percha / Q000627:therapeutic use*; D008768:Methylmethacrylates / Q000627:therapeutic use; D010482:Periapical Abscess / Q000209:etiology / Q000517:prevention & control*; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D012834:Silver / Q000627:therapeutic use*; D014025:Titanium / Q000627:therapeutic use*; D015035:Zinc Oxide-Eugenol Cement / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; D004853:Epoxy Resins; D008768:Methylmethacrylates; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; D012834:Silver; C028044:epoxy resin AH-26; C031667:IRM cement; D006171:Gutta-Percha; D014025:Titanium; D001729:Bismuth