Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP).
Psoriatic onycho-pachydermo-periostitis (POPP)is a rare subset of psoriatic arthritis, characterized by onychopathy, painful thickening of the periungual soft tissues, and radiological features consisting of an exuberant periosteal reaction of the terminal phalanx. The POPP treatment is debated, and side effect risk of therapies may not be offset by their benefits. We report on a successful treatment with carnitine in a 15-year old boy suffering from POPP.
Fietta
Pieranna
P
Osteo-Articular Department, Rheumatic Disease and Internal Medicine Unit, Hospital and University of Parma,Via Gramsci, 14,43100 Parma, Italy. farnese15@libero.it
Manganelli
Paolo
P
D000293:Adolescent; D015535:Arthritis, Psoriatic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D002331:Carnitine / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D054039:Onycholysis / Q000188:drug therapy / Q000209:etiology; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D013933:Thumb / Q000473:pathology; D014034:Toes / Q000473:pathology; D014803:Vitamin B Complex / Q000494:pharmacology / Q000627:therapeutic use*
D014803:Vitamin B Complex; D002331:Carnitine