[Bone and bone related biochemical examinations. Bone and collagen related metabolites. Tartrate-resistant acid phosphatase (TRACP)].
Tartrate-resistant acid phosphatase (TRACP) is a well-known marker for bone resorption, but it is not enough for clinical use in specificity of bone and instability in serum. Tartrate-resistant acid phosphatase type 5b (TRACP-5b) is an osteoclast-produced enzyme and was reported the clinical performance of a novel fragments absorbed immunocapture enzyme assay. TRACP-5b have smaller day-to-day and diurnal variation than those of urinary bone resorption markers and show the usefulness as promising markers in monitoring the treatment for osteoporosis.
Mochizuki
Yoshiko
Y
Dokkyo University School of Medicine, Department of Obstetrics and Gynecology.
D000135:Acid Phosphatase / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis*; D001862:Bone Resorption / Q000378:metabolism*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis*; D008297:Male; D000071681:Tartrate-Resistant Acid Phosphatase
D015415:Biomarkers; D007527:Isoenzymes; C000605510:ACP5 protein, human; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase