title: N-acyl-L-homoserine lactone quorum sensing controls butanediol fermentation in Serratia plymuthica RVH1 and Serratia marcescens MG1.
abstract: Butanediol fermentation in two Serratia species is shown to be affected by N-acyl-L-homoserine lactone-dependent quorum sensing. Knockout of quorum-sensing signal production caused a shift towards enhanced acid production, resulting in early growth arrest, which was reversible by the addition of synthetic signal molecules.
authors.affiliation: Centre for Food and Microbial Technology, Department of Microbial and Molecular Systems, Faculty of Bioscience Engineering, Katholieke Universiteit Leuven, Leuven, Belgium.
authors.forename: Rob
authors.initials: R
authors.lastname: Van Houdt
authors.forename: Pieter
authors.initials: P
authors.lastname: Moons
authors.forename: Maria
authors.initials: M
authors.lastname: Hueso Buj
authors.forename: Chris W
authors.initials: CW
authors.lastname: Michiels
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000502:physiology; D002072:Butylene Glycols / Q000378:metabolism*; D005285:Fermentation; D012705:Serratia / Q000378:metabolism / Q000502:physiology*
chemical_list: D002072:Butylene Glycols; C088386:homoserine lactone; D015107:4-Butyrolactone