title: [Racial mix of the panamanian population].
abstract: The racial admixture of a target population can be ascertained by quantifying the contribution to the genetic pool of each of its components (ancestral populations), which could be two, three or more. The racial admixture is of importance for the understanding of results derived from biomedical and anthropological studies. The main objective of this investigation is to determine the population frequencies of genetic systems ABO and Rh and to use these data to calculate the racial admixture of the country and of each sample province, fitting a trihybrid model. To achieve this, the Krieger method, implemented by the computer program Mistura 3, was applied to phenotypic data of systems ABO and Rh in a sample of 4,202 subjects born in seven provinces. In the general population of Panama, 38.72% of genes from the genetic pool have an African origin, 35.87%, an Amerindian origin and 25.40%, a Caucasian origin. In the province of Cocle we found a contribution of 16.47% of African genes, 55.25% of Amerindian genes and 28.28% of Caucasian genes. The province of Colon presents 69.34% of African genes, 25.00% of Amerindian genes and 5.65% of Caucasian genes. In contrast, Chiriquí presents 5.56% of African genes, 50.63% of Amerindian genes and 43.80% of Caucasian genes. The province of Herrera is characterized by the following proportions: 58.45% African genes, 28.44% Amerindian genes and 13.11% Caucasian genes. In the province of Los Santos there is a 62.29% African contribution, a 14.35% Amerindian contribution and a 22.72% Caucasian one. In the province of Panama there is a 57.01%, 26.25% and 16.74% contribution of African, Amerindian and Caucasian genes, respectively. Finally, in Veraguas a contribution of 18.59% of African genes, 44.29% of Amerindian genes and 37.12% of Caucasian genes was found.
authors.affiliation: Instituto del DNA y del Genoma Humano, Universidad de Panamá.
authors.forename: Tomás D
authors.initials: TD
authors.lastname: Arias
authors.forename: Edgardo
authors.initials: E
authors.lastname: Castro
authors.forename: Edward
authors.initials: E
authors.lastname: Ruiz
authors.forename: Ramiro
authors.initials: R
authors.lastname: Barrantes
authors.forename: Lucía
authors.initials: L
authors.lastname: Jorge-Nebert
mesh_terms: D000293:Adolescent; D000328:Adult; D001789:Blood Group Antigens / Q000032:analysis; D016021:Epidemiologic Studies; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D010176:Panama / Q000208:ethnology; D044469:Racial Groups / Q000706:statistics & numerical data*
chemical_list: D001789:Blood Group Antigens