The effect of pregnant mare serum gonadotropin on mouse oocytes as monitored at metaphase II.
Ovulated oocytes were collected from random-bred, 7-12 week old ICR mice injected with 0, 3, or 6 i.u. pregnant mare serum gonadotropin (PMSG). Analyses of 872 metaphase figures from 87 females did not show a significant increase in chromosomal imbalance with PMSG treatment. A tendency toward ovum fragmentation was noted with an increase in PMSG dose.
Gray
M H
MH
Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Chrisman
C L
CL