title: Enhancing the precision of quantitative water content mapping by optimizing sequence parameters.
abstract: This article describes a methodology for determining the precision of a recently published method for quantitative water content mapping using MRI. A framework for calculating the random error component as a function of sequence parameters is provided and predictions are compared with experimental results obtained in a phantom. The experimental and theoretical results are in good agreement and demonstrate that the precision of quantitative water content mapping can be significantly increased by a proper and objective choice of acquisition parameters.
authors.affiliation: Institut für Medizin, Forschungszentrum Jülich GmbH, Jülich, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Neeb
authors.forename: N J
authors.initials: NJ
authors.lastname: Shah
mesh_terms: D001929:Brain Edema / Q000378:metabolism; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012680:Sensitivity and Specificity; D014867:Water / Q000032:analysis* / Q000737:chemistry
chemical_list: D014867:Water