title: Mitochondrial dynamics and Ca2+ signaling.
abstract: Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.
authors.affiliation: Department of Experimental and Diagnostic Medicine and Interdisciplinary Center for the Study of Inflammation and ER-GenTech, University of Ferrara, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Szabadkai
authors.forename: A M
authors.initials: AM
authors.lastname: Simoni
authors.forename: K
authors.initials: K
authors.lastname: Bianchi
authors.forename: D
authors.initials: D
authors.lastname: De Stefani
authors.forename: S
authors.initials: S
authors.lastname: Leo
authors.forename: M R
authors.initials: MR
authors.lastname: Wieckowski
authors.forename: R
authors.initials: R
authors.lastname: Rizzuto
mesh_terms: D000818:Animals; D005075:Biological Evolution; D020013:Calcium Signaling; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000378:metabolism*