title: Efficacy of radiation therapy for the treatment of macroscopic canine oral soft tissue sarcoma.
abstract: This retrospective study evaluated the efficacy of radiotherapy used alone in macroscopic oral soft tissue sarcoma. Thirty-one dogs qualified for the study. Twenty dogs received curative radiotherapy (median total dose: 52.5 Gy) and eleven dogs were treated palliatively (3 x 8 Gy or 5 x 6 Gy). The time-to-progression for the curatively-treated dogs was 333 days versus 180 days for the palliatively-treated dogs (p=0.134). The overall survival was 331 days for the curative group and 310 days for the palliative group (p =0.2292). The results of this study suggest that radiation therapy is useful in the treatment of oral soft tissue sarcoma.
authors.affiliation: Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 260, 8057 Zürich, Switzerland. vpoirier@vetclinics.unizh.ch
authors.forename: Valérie J
authors.initials: VJ
authors.lastname: Poirier
authors.forename: Carla Rohrer
authors.initials: CR
authors.lastname: Bley
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Roos
authors.forename: Barbara
authors.initials: B
authors.lastname: Kaser-Hotz
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000401:mortality / Q000473:pathology* / Q000532:radiotherapy*; D004285:Dogs; D019583:Dose Fractionation, Radiation; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005500:Follow-Up Studies; D008297:Male; D009062:Mouth Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000662:veterinary*; D012189:Retrospective Studies; D012509:Sarcoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000662:veterinary*; D016019:Survival Analysis; D013997:Time Factors