title: NT-proBNP measurements in high-risk diabetic patients--a case series from Mamelodi (Gauteng).
abstract: The prevalence of raised BNP values is unknown in South African urban black populations at risk for heart failure. This study determined the frequency of raised NT-proBNP and the correlates of NT-proBNP in a high-risk diabetic population.
  
  
  METHODS
  A cross-sectional convenience sample of diabetic patients at the Mamelodi Hospital diabetes clinic was examined. Data on clinical, biometric, biochemical and a sixminute walk test were collected.
  
  
  RESULTS
  Sixty patients (38 female) were examined. The frequency of elevated NT-proBNP was 22% (95% CI; 12-34%). Univariate analysis found systolic blood pressure (BP) (p = 0.007) and duration of diabetes (p = 0.005) to be predictive of an elevated NT-proBNP.
authors.affiliation: Department of Internal Medicine, School of Medicine, University of Pretoria, Pretoria, South Africa.
authors.forename: A
authors.initials: A
authors.lastname: Deffur
authors.forename: J A
authors.initials: JA
authors.lastname: Ker
authors.forename: P
authors.initials: P
authors.lastname: Rheeder
authors.forename: M M
authors.initials: MM
authors.lastname: Van Niekerk
authors.forename: S J
authors.initials: SJ
authors.lastname: Quinton
mesh_terms: D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D016017:Odds Ratio; D010446:Peptide Fragments / Q000097:blood*
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain