Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes.
This article summarizes the proceedings of a symposium that took place at the 2005 meeting of the Research Society on Alcoholism. The organizers/chairs were Daniel Goldowitz and Katheen A. Grant. The presentations were as follows: (1) High-Throughput Screening for Ethanol Phenotypes, by Douglas B. Matthews and Kristin M. Hamre; (2) Genetic Basis of Schedule-Induced Polydipsia in Mice, by Guy Mittleman and Elissa J. Chesler; (3) Effects of Stress and Ethanol Dependence on Ethanol Self-administration in Inbred and Mutant Mice, by Howard C. Becker and Marcelo F. Lopez; (4) Changes in Dopaminergic Mechanisms Associated With Ethanol Dependence, by Sara R. Jones and Tiffany A. Mathews; and (5) Defining Brain Region-Specific Gene Networks Relevant to Ethanol Behaviors, by Michael F. Miles and Robnet Kerns.
Goldowitz
Daniel
D
University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA. dgold@nb.utmem.edu
Matthews
Douglas B
DB
Hamre
Kristin M
KM
Mittleman
Guy
G
Chesler
Elissa J
EJ
Becker
Howard C
HC
Lopez
Marcelo F
MF
Jones
Sara R
SR
Mathews
Tiffany A
TA
Miles
Michael F
MF
Kerns
Robnet
R
Grant
Kathleen A
KA
D000437:Alcoholism / Q000235:genetics*; D000818:Animals; D001007:Anxiety / Q000235:genetics*; D001522:Behavior, Animal; D001921:Brain / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology; D004298:Dopamine / Q000502:physiology; D004777:Environment; D000431:Ethanol / Q000008:administration & dosage; D051379:Mice; D008815:Mice, Inbred Strains; D008817:Mice, Mutant Strains; D010641:Phenotype; D012646:Self Administration; D013312:Stress, Physiological / Q000235:genetics*
D000431:Ethanol; D004298:Dopamine