Chromosomal abnormalities and psychosis.
The search for susceptibility genes for schizophrenia and severe affective disorder has been enhanced by the study of cytogenetic abnormalities that disrupt genes directly. One such gene is DISCI and there is increasing evidence that it may be an important modulator of risk of psychosis.
Muir
Walter J
WJ
Pickard
Benjamin S
BS
Blackwood
Douglas H R
DH
D002869:Chromosome Aberrations; D020022:Genetic Predisposition to Disease; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics; D011618:Psychotic Disorders / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics
C412476:DISC1 protein, human; D009419:Nerve Tissue Proteins