title: [Elaboration of biodegradable polymer substrate for cultivation of human dermal fibroblasts].
abstract: The influence of polylactic acid (PLA) surface films on the pattern of cell behavior was studied. The human dermal fibroblasts were cultivated on PLA covered glasses. The hydrophobic nature of PLA films depends on the availability of polymer solvent in the film preparation. PLA films obtained from a more polar solvent--aceton--appeared to be more hydrophilic than those obtained from methylene chloride. More hydrophilic polymer films also appeared to be more preferable for cell cultivation, and human dermal fibroblasts demonstrated a better adhesion and proliferation on hydrophilic rather than on hydrophobic PLA films.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Shved
authors.forename: L V
authors.initials: LV
authors.lastname: Kukhareva
authors.forename: I M
authors.initials: IM
authors.lastname: Zorin
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Solov'ev
authors.forename: M I
authors.initials: MI
authors.lastname: Blinova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Bilibin
authors.forename: G P
authors.initials: GP
authors.lastname: Pinaev
mesh_terms: D000096:Acetone; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism* / Q000592:standards; D002448:Cell Adhesion; D002478:Cells, Cultured; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019344:Lactic Acid / Q000737:chemistry / Q000378:metabolism / Q000592:standards; D008422:Materials Testing; D008752:Methylene Chloride; D011091:Polyesters; D011108:Polymers / Q000737:chemistry / Q000378:metabolism / Q000592:standards; D012867:Skin; D012997:Solvents
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D012997:Solvents; D000096:Acetone; D019344:Lactic Acid; C033616:poly(lactide); D008752:Methylene Chloride