[Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens].
OBJECTIVE
To study the chemical constituents possessing cytotoxicity activity from Elaeagnus pungens.


METHODS
The constituents were separated through repeated chromatographic methods and their structures were elucidated by spectral analysis.


RESULTS
Five compounds were isolated from the ethyl acetate ether extract of leaves of E. pungens. Their structures were elucidated as 4-hydroxybenzoic acid (1), 3, 3'-dimethoxyquercetin (2), caffeic acid methyl ester (3), methyl 3, 4-dihydroxybenzoate (4), spingic acid (5), 4-methoxylbenzoic acid (6), 3-methylkaempferol (7), kaempferol-3-O-beta-D-glucoside (8), dausosterol (9).


CONCLUSIONS
Compounds 1-8 were isolated from this plant for the first time.
Zhao
Xin
X
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
Zhu
Rui-Liang
RL
Jiang
Biao
B
Huang
Hao
H
D002109:Caffeic Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D049109:Cell Proliferation / Q000187:drug effects; D031263:Elaeagnaceae / Q000737:chemistry*; D006367:HeLa Cells / Q000166:cytology; D006801:Humans; D044949:Kaempferols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010226:Parabens / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
C464826:3-methylkaempferol; D002109:Caffeic Acids; D044949:Kaempferols; D010226:Parabens; C060385:3,3'-di-O-methylquercetin; D011794:Quercetin; C038193:4-hydroxybenzoic acid; C497945:caffeic acid methyl ester