title: [First documented case of Chryseobacterium meningosepticum meningitis in Central African Republic].
abstract: Chryseobacterium meningosepdcum is a rare but well-known causative agent of bacterial meningitis and can be the source of epidemic outbreak in neonatal facilities. It has rarely been documented in Africa. The purpose of this report is to describe the first case of C. meningosepticum meningitis in Central African Republic. The case that remained isolated occurred after dystocic delivery with resuscitation in a neonatal unit. Despite intensive care and appropriate antibiotic treatment, the newborn died on day 19. Identification of this rare cause of meningitis underlines the important role of the bacteriologic laboratory in managing bacterial meningitis in Africa. The strain of C. meningosepticum involved in this case was resistant to the main antibiotics used for first-intention treatment of neonatal bacterial meningitis, i.e., third-generation cefalosporins, chioramphenicol, and aminosides. This case also underlines the importance of familiarizing the medical staff with the dangers of nosocomial meningitis and reinforcing hospital hygiene measures.
authors.affiliation: Clinique médicale infantile du Complexe Pédiatrique, BP 607, Bangui, République Centrafricaine. bobossi@yahoo.fr
authors.forename: G
authors.initials: G
authors.lastname: Bobossi-Serengbe
authors.forename: J C
authors.initials: JC
authors.lastname: Gody
authors.forename: N E
authors.initials: NE
authors.lastname: Beyam
authors.forename: R
authors.initials: R
authors.lastname: Bercion
mesh_terms: D002488:Central African Republic; D045247:Chryseobacterium; D017809:Fatal Outcome; D005260:Female; D045826:Flavobacteriaceae Infections / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D016920:Meningitis, Bacterial / Q000175:diagnosis*