title: Acute percutaneous lactic acid poisoning in a child.
abstract: Percutaneous poisoning is quite rare, and in particular, topical lactic acid poisoning is even more so. We report a young girl with lamellar ichthyosis and symptoms of poisoning, with clinical signs of irritability, agitation, myoclonia, and difficulty in walking, accompanied by lactic acidosis as a result of the more frequent than recommended application of emollients containing lactic acid. The clinical symptoms resolved upon discontinuation of the topical treatment. Among the possible causes of metabolic acidosis, health care providers should be aware of the possibility of percutaneous poisoning.
authors.affiliation: Pediatrics Service, Integrated Pediatrics Unit, Emergency Section, Hospital Sant Joan de Déu-Hospital Clínic, Universidad de Barcelona, Barcelona, Spain. 35902mer@comb.es
authors.forename: Manuela Esteban
authors.initials: ME
authors.lastname: Ramírez
authors.forename: Wael Fasheh
authors.initials: WF
authors.lastname: Youseef
authors.forename: Roser Garrido
authors.initials: RG
authors.lastname: Romero
authors.forename: José María Quintillá
authors.initials: JM
authors.lastname: Martínez
authors.forename: Maria Antonia
authors.initials: MA
authors.lastname: González-Enseñat
authors.forename: Xavier Sanmartí
authors.initials: XS
authors.lastname: Vilaplana
authors.forename: Carles Luaces
authors.initials: CL
authors.lastname: Cubells
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D000279:Administration, Cutaneous; D005260:Female; D006801:Humans; D017490:Ichthyosis, Lamellar / Q000188:drug therapy; D007223:Infant; D019344:Lactic Acid / Q000008:administration & dosage* / Q000506:poisoning*
chemical_list: D019344:Lactic Acid