title: Improvement of polyuria, bladder sensation and bladder capacity following renal transplantation.
abstract: Here, we report a patient with renal failure and bladder dysfunction whose symptoms improved following renal transplantation. A 23-year-old woman underwent renal transplantation for renal failure as a result of dysplastic kidneys. Urodynamic evaluation prior to transplantation showed decreased bladder sensation and increased bladder capacity, probably because of congenital polyuria. One week after surgery, dry mouth disappeared, and urine volume normalized gradually. Urodynamic studies performed 3 and 10 months after transplantation showed improvement of bladder function, and the frequency/volume charts of urination also showed normalization of urine volume. Renal and bladder functions were almost normal 45 months after transplantation. Bladder dysfunction involves numerous factors, but the primary cause was probably congenital polyuria in the present case. This case suggested that blood purification and correction of urine volume by renal transplantation might lead to restoration of normal bladder function.
authors.affiliation: Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Hiroya
authors.initials: H
authors.lastname: Mizusawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishizuka
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Igawa
authors.forename: Motokiyo
authors.initials: M
authors.lastname: Komiyama
authors.forename: Kyoko
authors.initials: K
authors.lastname: Irie
authors.forename: Kenji
authors.initials: K
authors.lastname: Iwata
authors.forename: Osamu
authors.initials: O
authors.lastname: Nishizawa
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D011141:Polyuria / Q000503:physiopathology* / Q000601:surgery*; D001743:Urinary Bladder / Q000502:physiology* / Q000503:physiopathology / Q000601:surgery*