Complex partial seizure symptom endorsement in individuals with a history of head injury.
Research has shown that subjects at risk for cerebral dysfunction endorse more complex partial seizure symptoms than low risk controls. It has been suggested that seizure activity be regarded as occurring on a continuum of neurobehavioral dysfunction, rather than as a discrete syndrome. The present study assessed seizure symptom endorsement in individuals reporting a positive history of head injury. There were three groups of college student participants: head injury with loss of consciousness (LOC; n=31); head injury followed by a dazed period or alteration of consciousness (AOC; n=36); non-injured controls (NHI; n=60). In general, the LOC group reported greater frequency of symptomatology and a greater number of clinically significant symptoms (above the 90th percentile) than the NHI group, and a greater number of clinically significant symptoms than the AOC group. The AOC group did not differ from the NHI group on either variable. These results lend credence to the concept of a continuum representing an epilepsy spectrum disorder.
Ryan
Laurie M
LM
Defense and Veterans Brain Injury Center, Walter Reed Army Medical Center, Department of Neurology, DC, United States. ryanl@mail.nih.gov
O'Jile
Judith R
JR
Parks-Levy
Judith
J
Betz
Brian
B
Hilsabeck
Robin C
RC
Gouvier
Wm Drew
WD
D000293:Adolescent; D000328:Adult; D006259:Craniocerebral Trauma / Q000150:complications* / Q000453:epidemiology; D004185:Disability Evaluation; D017029:Epilepsy, Complex Partial / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012306:Risk; D011795:Surveys and Questionnaires; D015599:Trauma Severity Indices; D014474:Unconsciousness / Q000150:complications