[Progress of cancer stem cells of solid tumor].
Stem cells have some characteristics similar to tumor cells, and may be the origin of tumor cells. Stem cell-like subpopulation has been isolated and identified from hematopoietic system malignancies and solid tumors, and defined as cancer stem cells. Cancer stem cells play important roles in the initiation and progression of malignancies. Tumor might be a kind of diseases of stem cells, and this finding may help to understand the mechanisms of tumorigenesis and instruct clinical therapeutics.
Ni
Xiao-Guang
XG
Department of Endoscopy, Cancer Institute/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, P. R. China. nixiaoguang@yahoo.com.cn
Zhao
Ping
P
D000071916:AC133 Antigen; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters / Q000032:analysis; D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology; D000818:Animals; D015703:Antigens, CD / Q000032:analysis; D018951:Antigens, CD20 / Q000032:analysis; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D018960:Hyaluronan Receptors / Q000032:analysis; D008175:Lung Neoplasms / Q000737:chemistry / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000737:chemistry / Q000473:pathology; D009363:Neoplasm Proteins / Q000032:analysis; D014411:Neoplastic Stem Cells / Q000737:chemistry / Q000473:pathology / Q000502:physiology; D010455:Peptides / Q000032:analysis; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology; D019572:Retinal Neoplasms / Q000737:chemistry / Q000473:pathology; D012175:Retinoblastoma / Q000737:chemistry / Q000473:pathology
C116614:ABCG2 protein, human; D000071916:AC133 Antigen; D000070997:ATP Binding Cassette Transporter, Subfamily G, Member 2; D018528:ATP-Binding Cassette Transporters; D015703:Antigens, CD; D018951:Antigens, CD20; C497483:CD44 protein, human; D006023:Glycoproteins; D018960:Hyaluronan Receptors; D009363:Neoplasm Proteins; D010455:Peptides