title: Assessments in ankylosing spondylitis.
abstract: Assessment of disease status and response to therapy in ankylosing spondylitis is a rapidly expanding area of research. The assessment in ankylosing spondylitis international working group has contributed greatly to this development, defining core sets of health domains for use in daily practice and in clinical trials, developing and validating measurement instruments corresponding to these health domains, and developing response and remission criteria for use in clinical trials. This chapter reviews available measures of three major areas of disease impact in ankylosing spondylitis (disease activity, structural damage and functioning), and discusses which measures are relevant for use in clinical practice.
authors.affiliation: Rheumazentrum-Ruhrgebiet, Landgrafenst 15, 44649 Herne, Germany. zochling@rheumazentrum-ruhrgebiet.de
authors.forename: Jane
authors.initials: J
authors.lastname: Zochling
authors.forename: Jürgen
authors.initials: J
authors.lastname: Braun
authors.forename: Désirée
authors.initials: D
authors.lastname: van der Heijde
mesh_terms: D018450:Disease Progression; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D010147:Pain Measurement; D011379:Prognosis; D011788:Quality of Life; D012720:Severity of Illness Index; D013167:Spondylitis, Ankylosing / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome