ARDS and diffuse alveolar damage: a pathologist's perspective.
Diffuse alveolar damage (DAD) is the histologic correlate of most patients with adult respiratory distress syndrome (ARDS). It is a relatively straight forward diagnosis and the main differential diagnosis clinically is acute pneumonia and histologically is bronchiolitis obliterans and organizing pneumonia (BOOP). The histologic progression of DAD includes 3 phases (exudative, proliferative, and fibrotic) that correlate with the time rather than its specific cause. The factors that govern which patients will do well and which will develop a fulminant course is not known.
Castro
Claudia Y
CY
The University of Texas Medical Branch (UTMB), Department of Pathology, Galveston, TX 77555, USA. cycastro@utmb.edu
D001706:Biopsy; D018549:Cryptogenic Organizing Pneumonia / Q000473:pathology; D006801:Humans; D011650:Pulmonary Alveoli / Q000473:pathology*; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000473:pathology*