title: Coverage of the cranium with latissimus dorsi in the recurrent basal cell carcinoma of Gorlin syndrome: for protection against clinical invasion.
abstract: Gorlin's syndrome is a genetic disorder of autosomal dominant inheritance with characterized primarily by five major findings: multiple basal cell carsinoma (BCC), jaw cysts, pits on the palms and soles, ectopic calcification of the falx cerebri and skeletal anomalies. BCC is the most frequently accompanied tumor with this syndrome. The risk of recurrent BCC with Gorlin's syndrome is higher than non-syndromic BCC. The authors present a 25-year-old man affected by recurrent basal cell carcinoma on the scalp. The patient was treated by excising the tumor and reconstructing latissimus dorsi musculocutaneous flap. The fascial component of the scalp forms an additional layer between the skin and the cranium. This structure creates an extra distance before the invasion into the cranium which needs to be penetrated by the skin tumor. Muscle tissue transformed in scalp reconstruction imitates the fascia layer in forming an additional layer against the invasion of skin tumors such as recurrent BCC into the cranium. Free flap reconstruction for recurrent scalp BCC can be best therapy model at Gorlin's syndrome.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Süleyman Demirel University School of Medicine, Isparta, Turkey. snasir@med.sdu.edu.tr
authors.forename: Serdar
authors.initials: S
authors.lastname: Nasir
authors.forename: Aycan
authors.initials: A
authors.lastname: Kayikcioglu
authors.forename: Mustafa Asim
authors.initials: MA
authors.lastname: Aydin
authors.forename: Gökhan
authors.initials: G
authors.lastname: Tunçbilek
mesh_terms: D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000601:surgery*; D002280:Basal Cell Carcinoma / Q000601:surgery*; D002985:Clinical Protocols; D005205:Fascia / Q000637:transplantation; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000637:transplantation*; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012535:Scalp / Q000601:surgery*; D012878:Skin Neoplasms / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods; D012886:Skull / Q000601:surgery*