title: [The role of macro-elements in the human body].
abstract: The authors summarize the role of essential macro metal elements (Na, K, Ca, Mg) in human body: their homeostasis, absorption, transport, storage and excretion. Metabolism of macro-elements, daily requirements, cause of metal deficiencies and diseases caused by deficiencies are also discussed. Messenger and prooxidant effect of Ca2+-ions, indirect antioxidant effect of Mg2+-ions and the adjuvant application of magnesium are also reviewed.
authors.affiliation: Magyar Tudományos Akadémia, Kémiai Kutatóközpont, Anyag- és Környezetkémiai Intézet, Budapest.
authors.forename: Béla
authors.initials: B
authors.lastname: Lakatos
authors.forename: József
authors.initials: J
authors.lastname: Balla
authors.forename: Péter
authors.initials: P
authors.lastname: Vinkler
authors.forename: Klára
authors.initials: K
authors.lastname: Szentmihályi
mesh_terms: D000975:Antioxidants / Q000493:pharmacokinetics; D001693:Biological Transport, Active; D002118:Calcium / Q000172:deficiency; D015220:Calcium Channels / Q000378:metabolism; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics*; D003677:Deficiency Diseases / Q000175:diagnosis / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D007473:Ion Channels / Q000378:metabolism*; D017136:Ion Transport / Q000502:physiology; D017616:Magnesium Compounds / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics*; D008275:Magnesium Deficiency / Q000378:metabolism; D016877:Oxidants / Q000493:pharmacokinetics; D015221:Potassium Channels / Q000378:metabolism; D011191:Potassium Deficiency / Q000378:metabolism; D017419:Potassium, Dietary / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics*; D012964:Sodium / Q000172:deficiency; D015222:Sodium Channels / Q000378:metabolism; D012982:Sodium, Dietary / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics*
chemical_list: D000975:Antioxidants; D015220:Calcium Channels; D002136:Calcium, Dietary; D007473:Ion Channels; D017616:Magnesium Compounds; D016877:Oxidants; D015221:Potassium Channels; D017419:Potassium, Dietary; D015222:Sodium Channels; D012982:Sodium, Dietary; D012964:Sodium; D002118:Calcium