title: CT appearance of Varicella Zoster lesions in liver and spleen in an immunocompetent patient.
abstract: An adult patient presented with vesicular rash and abdominal pain of 5 days duration. His initial laboratory results showed elevated liver enzymes. A contrast enhanced CT scan demonstrated multiple small hypodense nodules in liver and spleen. His serum was reactive for Varicella Zoster IgM. Patient was treated with intravenous Acyclovir for 5 days and followed up with oral tablets for 2 weeks. At 3 weeks, CT scan showed resolution of hypodense nodules and his serum liver enzymes returned to normal at 6 weeks. Patient is on follow up and asymptomatic for 2 years. The CT appearances of nodules and their resolution following specific antiviral therapy are useful in diagnosis and in follow up of disseminated Varicella Zoster.
authors.affiliation: Department of Diagnostic Radiology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, Lower Kent Ridge Road, Singapore 119074, Singapore. dnrskv@nus.edu.sg
authors.forename: Sudhakar Kundapur
authors.initials: SK
authors.lastname: Venkatesh
authors.forename: Lena Li-Lin
authors.initials: LL
authors.lastname: Lo
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002644:Chickenpox / Q000000981:diagnostic imaging* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007121:Immunocompetence; D007902:Length of Stay; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D008297:Male; D013154:Spleen / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir