[Usefulness of measurement of glucose and glycosylated hemoglobin levels in patients with acute coronary syndrome as predictors of number of stenotic coronary arteries as shown in coronary arteriography].
Data on corelation between diabetes and multivessel coronary disease have been documented. The aim of the study was to estimate usefulness of measurement of glucose and glygosylated haemoglobin levels in patients with acute coronary syndrome as a predictors of number of stenotic coronary arteries shown in coronary arteriography.


METHODS
We examined 386 patients (mean age was 61 +/- 10, men/ women 263/123). All of them underwent coronary angiography 81 patients (21%) had diabetes. A routine examination included age, sex, clinical state, BMI, WHR, plasma lipids, coagulative parameters, glucose level, HbA1c level, urea, creatine, C-reactive protein levels, blood pressure and heart failure traits.


RESULTS
There were 11.2% patients without any changes in coronary arteries, 28.4% patients with one or two stenotic arteries and 60.4% patients with more than two stenotic coronary arteries. We observed that glucose and HbA1c levels were significantly higher in group without any changes vs group with one or two stenotic vessels and more than two stenotic vessels. The differences were still statistically significant in patients with diabetes and HbA1c over 6.2%.


CONCLUSIONS
In conclusion, measurement of glucose and glycosylated haemoglobin levels in moment of diagnosis acute coronary syndrome can have prognostic estimation of number of stenotic arteries.
Markuszewski
Leszek
L
Uniwersytet Medyczny w Lodzi: Oddział Kliniczny Kardiologii Interwencyjnej i Kardiodiabetologii, I Katedra Kardiologii i Kardiochirurgii.
Bodalska
Joanna
J
Kamiński
Grzegorz
G
Kuberska-Kedzierska
Małgorzata
M
D000208:Acute Disease; D001786:Blood Glucose / Q000032:analysis*; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000097:blood* / Q000000981:diagnostic imaging* / Q000209:etiology; D048909:Diabetes Complications / Q000097:blood; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests
D001786:Blood Glucose; D006442:Glycated Hemoglobin