Comparison of the BACTEC 9240 and BacT/Alert blood culture systems for detection of bacterial contamination in platelet concentrates.
The BACTEC 9240 blood culture system with a standard aerobic medium, Plus Aerobic/F, was compared to the BacT/Alert system with a platelet-specific medium, BPA, as a means for detecting bacterial contamination of platelet preparations. One hundred thirteen platelet units seeded with low levels of different bacteria were examined with both systems. In 93 instances, growth was detected first in the BACTEC system; in 12 cases, growth registered first in the BacT/Alert system. Among all comparisons, growth was detected, on average, 1.7 h sooner with the BACTEC system. The differences in length of time to detection were statistically significant.
Riedel
Stefan
S
Division of Clinical Microbiology and Transfusion Medicine, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Siwek
Gregory
G
Beekmann
Susan E
SE
Richter
Sandra S
SS
Raife
Thomas
T
Doern
Gary V
GV
D016470:Bacteremia / Q000382:microbiology* / Q000517:prevention & control; D001419:Bacteria / Q000254:growth & development / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000382:microbiology / Q000517:prevention & control; D001431:Bacteriological Techniques / Q000592:standards; D001769:Blood / Q000382:microbiology; D001792:Blood Platelets / Q000166:cytology / Q000382:microbiology*; D002478:Cells, Cultured; D003470:Culture Media; D004340:Drug Contamination / Q000517:prevention & control; D006801:Humans; D017713:Platelet Transfusion / Q000009:adverse effects
D003470:Culture Media