title: [Constituents in the alkaloid fraction of Kushen decoction].
abstract: OBJECTIVE
  To study the chemical constituents of the alkaloid fraction of Kushen decoction.
  
  
  METHODS
  Constituents were isolated by different kinds of column chromatography and their structures were elucidated with spectral methods.
  
  
  RESULTS
  Eight compounds were isolated and identified as matrine (I), sophoridine (II), sophocarpine (III), sophoramine (IV), oxymatrine (V), oxysophocarpine (VI), aloperine (VII) and sparteine (VIII).
  
  
  CONCLUSIONS
  All these compounds were isolated from Kushen decoction for the first time. Aloperine was found firstly in Sophora flavescens, or Scutellaria baicalensis, or Rehmannia glutinosa which constituted Kushen decoction.
authors.affiliation: School of Chinese Pharmacology, Beijing University of Traditional Chinese Medicine, Beijing 100102, China. liubinyn67@163.com
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Ren-Bing
authors.initials: RB
authors.lastname: Shi
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D054837:Quinolizidines; D011807:Quinolizines / Q000737:chemistry / Q000302:isolation & purification; D032267:Rehmannia / Q000737:chemistry; D031364:Scutellaria baicalensis / Q000737:chemistry; D029909:Sophora / Q000737:chemistry; D000093842:Matrines
chemical_list: D000470:Alkaloids; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010880:Piperidines; D054837:Quinolizidines; D011807:Quinolizines; C062701:aloperine; C035933:sophocarpine; C494416:kushen; D000093842:Matrines