[Tuberculosis in HIV infected children].
Tuberculosis (TB) is important threat in HIV-infected people. Although there is slow but constant decline TB-infections among adults and children in Poland, about 30% HIV-(+) adults is coinfected with TB. There were 12 cases of TB in HIV(+) children diagnosed in Department of Pediatric Infectious Diseases in 1994-2005. The aim was analysis of reasons for TB diagnostic tests in HIV (+) children, coinfection HIV and TB and efficacy of anti TB treatment. TB diagnostics was performed in 23 children because of clinical indications (15/23) and conversion or excessive skin tests (8/23). There were bacteriological and radiological exams done in all cases of TB suspicion. When active TB was diagnosed there were 4 tuberculostatic drugs used (6-12 months). In latent or unlocalized TB-INH was used for 12 months.


RESULTS
12 cases of TB infection were diagnosed: active TB--4, BCG-itis--1, latent--1 and unlocalized TB--6. In 10 cases TB infection was excluded. All cases of tuberculostatic treatment was successful. 5/12 cases are presently treated.


CONCLUSIONS
Skin test is lonely, generally used method of TB control in HIV (+) children without clinical manifestations of TB. There is a necessity of diagnosis and chemoprophylaxis in all cases of conversion or enlarged (above 10 mm, vesicularis) skin test. TB diagnosis is an indication for HIV diagnostics.
Popielska
Jolanta
J
Klinika Chorób Zakaźnych Wieku Dzieciecego, Instytutu Chorób Zakaźnych i Pasozytniczych AM w Warszawie. jolantapopielska@wp.pl
Marczyńska
Magdalena
M
Dobosz
Sabina
S
Szczepańska-Putz
Małgorzata
M
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000293:Adolescent; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D006679:HIV Seropositivity / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D011044:Poland; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy
D019380:Anti-HIV Agents; D000995:Antitubercular Agents