[Correlation of expressions of ER and CD59 in Buerger disease].
OBJECTIVE
To inquire into the expression conditions of ER, CD59 and IgG in Buerger disease arteria vessels and probe their correlation.


METHODS
Two groups of arteria vascular endothelial cells were investigated. The cells in Buerger group were derived from 30 male Buerger disease patients; the cells in the other group were derived from 30 normal men. The levels of ER, CD59 and IgG expression were detected by immunohistochemistry staining.


RESULTS
The levels of ER and CD59 expression in Buerger disease group were higher than those of control group (P<0.05); the level of IgG expression on arteria intima in Buerger group was lower than that of control group (P<0.05); the level of IgG expression under arteria intima in Buerger group was higher than that of control group (P<0.05). Spearman rank correlation analysis of the Buerger group showed that ZD59 expression and IgG expression are significantly correlated and ER expression and IgG expression are significantly correlated, too.


CONCLUSIONS
The expressions of CD59 and ER are up-regulated, which are probably
Deng
Jing-yu
JY
Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
De
Shi
S
He
Sheng
S
Chen
Bo
B
D000328:Adult; D001158:Arteries / Q000166:cytology / Q000378:metabolism; D018957:CD59 Antigens / Q000096:biosynthesis* / Q000235:genetics; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000235:genetics; D008297:Male; D011960:Receptors, Estrogen / Q000096:biosynthesis* / Q000235:genetics; D013919:Thromboangiitis Obliterans / Q000378:metabolism*; D017539:Tunica Intima
D018957:CD59 Antigens; D007074:Immunoglobulin G; D011960:Receptors, Estrogen