Intrapartum asphyxia and cerebral palsy: is there a link?
Perinatal hypoxic-ischemic cerebral injury, secondary to interruption of placental blood flow that results in cerebral palsy (CP), is a rare event. The ability to link an intrapartum event to subsequent CP should include a history of a sentinel event during labor, followed by the delivery of a depressed acidemic infant, and the subsequent evolution of neonatal encephalopathy, systemic organ injury, and acute neuroimaging abnormalities.
Perlman
Jeffrey M
JM
Department of Pediatrics, Weill Cornell Medical Center, New York, NY 10021, USA. jmp2007@med.cornell.edu
D001034:Apgar Score; D016887:Cardiopulmonary Resuscitation; D002547:Cerebral Palsy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D005323:Fetal Monitoring; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000503:physiopathology; D007231:Infant, Newborn; D011247:Pregnancy; D012307:Risk Factors