title: [Clinical significance of pelvic lymph-node dissection for the patients with locally invasive bladder cancer--correlation between the number of retrieved lymph nodes and prognosis].
abstract: The objective of this study was to know the effects of pelvic lymph node dissection on the survival of the patients who received radical cystectomy without neoadjuvant chemotherapy or radiotherapy. Between 1984 and 2000, 104 patients underwent operation at our institution for tumors clinically diagnosed as locally invasive bladder cancer (T2-4NxM0). Survival rates and 8 prognostic factors (age, sex, size, multiplicity, type, pT, N, pv) were analyzed by uni- and multivariate analysis. The significant factors were size, type, pT, N, pv by univariate analysis. Of these 5 factors, N factor was the most significant by multivariate analysis. Patients (N-) who had more than 20 lymph nodes retrieved showed better survival than the others.
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Sumio
authors.initials: S
authors.lastname: Noguchi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Takase
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Oogo
authors.forename: Kentaro
authors.initials: K
authors.lastname: Muraoka
authors.forename: Koichi
authors.initials: K
authors.lastname: Shioi
authors.forename: Masahumi
authors.initials: M
authors.lastname: Nakamura
authors.forename: Tatsuaki
authors.initials: T
authors.lastname: Onuki
authors.forename: Hiroichi
authors.initials: H
authors.lastname: Kishi
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Satomi
authors.forename: Momokuni
authors.initials: M
authors.lastname: Fukuda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002452:Cell Count; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000401:mortality*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D010388:Pelvis; D011379:Prognosis; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*