title: Primary malignant melanoma of the bladder.
abstract: Primary malignant melanomma of bladder is extremely rare: 18 cases are reported to date. An 82 year-old man underwent trans-urethral resection of bladder for a bleeding tumor of the posterior wall. Histological diagnosis was melanoma of the bladder. There was no history of previous or regressed cutaneous malignant melanoma. Margins of the bladder lesion contained atypical melanocytes similar to those commonly seen in the periphery of primary mucous membrane lesions. Clinical studies and radiological examinations were negative for other primary site of melanoma. The patient had a bladder recurrence that was consistent with primary tumor and died of widespread disease 9 months after diagnosis.
authors.affiliation: Urology Department, San Martino's Hospital, University of Genoa, Genoa, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Pacella
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Gallo
authors.forename: Christian
authors.initials: C
authors.lastname: Gastaldi
authors.forename: Carlo
authors.initials: C
authors.lastname: Ambruosi
authors.forename: Giorgio
authors.initials: G
authors.lastname: Carmignani
mesh_terms: D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology*; D017211:Treatment Failure; D001749:Urinary Bladder Neoplasms / Q000473:pathology*