Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance.
We used state of the art CMR to define ranges for normal left ventricular volumes and systolic/diastolic function normalized to the influence of gender, body surface area and age. New CMR normalized ranges were modeled and displayed in graphical form for clinical use, with normalization for body surface area, gender, and age. The determination of normality, or the severity of abnormality, depends on the use of the appropriate reference ranges normalized to all 3 variables. These novel data have particular importance for clinical practice and clinical trials using CMR.
Maceira
A M
AM
Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Prasad
S K
SK
Khan
M
M
Pennell
D J
DJ
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003971:Diastole / Q000502:physiology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012737:Sex Factors; D018709:Statistics, Nonparametric; D013599:Systole / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*