[Design and application of biological rhythm automatic monitor and data analysis system].
OBJECTIVE
To design and develop a biological rhythm monitor and data analysis system for studying biological rhythm in animals under different conditions.


METHODS
The system was a distributed digital control system consisting of a computer and zeitgeber generators. Acquisition of data on animal activity and generation of zeitgeber were modularized to meet the multiple requirements of experiment. System functions and animal adaptability to this system were detected by monitoring the rhythm of mouse activities under different light-dark cycles.


RESULTS
The animal experiment showed that the functions of this system, including data acquisition, data communication, light regulation and data analysis, were qualified for application. There was no apparent malfunction.


CONCLUSIONS
The system is safe, reliable and easy to operate. The system could be a very useful system to study biological rhythm in animals.
Yang
Bo
B
Department of Biomedical Engineering, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Liu
Yan-you
YY
Li
Ying
Y
Liao
Ga
G
Wang
Xiao-jia
XJ
Wang
Zheng-rong
ZR
D000818:Animals; D002940:Circadian Rhythm; D004867:Equipment Design; D051379:Mice; D008813:Mice, Inbred ICR; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D012815:Signal Processing, Computer-Assisted