title: Hemophagocytic lymphohistiocytosis complicating influenza A infection.
abstract: During the influenza A (H3N2) season of 2003-2004, several influenza-related complications and deaths were reported in children. Hemophagocytic lymphohistiocytosis complicating influenza A infection is very rare. We report a 3-year-old girl who presented with severe pneumonia and hemophagocytic lymphohistiocytosis associated with influenza A infection. Clinicians should be aware of hemophagocytic syndrome as a serious complication of influenza A infection.
authors.affiliation: Department of Anesthesiology, Section on Pediatric Critical Care Medicine, Wake Forest University School of Medicine and Brenner Children's Hospital, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1009, USA. smou@wfubmc.edu
authors.forename: Steven S
authors.initials: SS
authors.lastname: Mou
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Nakagawa
authors.forename: Ellen C
authors.initials: EC
authors.lastname: Riemer
authors.forename: Thomas W
authors.initials: TW
authors.lastname: McLean
authors.forename: Michael H
authors.initials: MH
authors.lastname: Hines
authors.forename: Avinash K
authors.initials: AK
authors.lastname: Shetty
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D053122:Influenza A Virus, H3N2 Subtype; D007251:Influenza, Human / Q000150:complications*; D051359:Lymphohistiocytosis, Hemophagocytic / Q000209:etiology* / Q000473:pathology / Q000628:therapy
chemical_list: D016756:Immunoglobulins, Intravenous