title: [Design and application of biological rhythm automatic monitor and data analysis system].
abstract: OBJECTIVE
  To design and develop a biological rhythm monitor and data analysis system for studying biological rhythm in animals under different conditions.
  
  
  METHODS
  The system was a distributed digital control system consisting of a computer and zeitgeber generators. Acquisition of data on animal activity and generation of zeitgeber were modularized to meet the multiple requirements of experiment. System functions and animal adaptability to this system were detected by monitoring the rhythm of mouse activities under different light-dark cycles.
  
  
  RESULTS
  The animal experiment showed that the functions of this system, including data acquisition, data communication, light regulation and data analysis, were qualified for application. There was no apparent malfunction.
  
  
  CONCLUSIONS
  The system is safe, reliable and easy to operate. The system could be a very useful system to study biological rhythm in animals.
authors.affiliation: Department of Biomedical Engineering, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Yan-you
authors.initials: YY
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.forename: Ga
authors.initials: G
authors.lastname: Liao
authors.forename: Xiao-jia
authors.initials: XJ
authors.lastname: Wang
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Wang
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D004867:Equipment Design; D051379:Mice; D008813:Mice, Inbred ICR; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D012815:Signal Processing, Computer-Assisted