Sclerosing stromal tumour of the ovary--a clinicopathologic spectrum.
Majority of the Sclerosing stromal tumours of the ovary documented in the literature are single case reports. We report a series of 4 cases. Among the 4 cases encountered the mean age at presentation was 22.2 years. The clinical presentation varied from asymptomatic mass per abdomen (2 cases), menorrhagia (1 case) and amenorrhoea (1 case). The tumour was unilateral in all the cases with an average size of 10 cms. Grossly the appearances varied from a solid, partly cystic, edematous tumour (2 cases) to solid,firm tumour with yellow flecks (1 case) to unilocular cystic tumour (1 case). Microscopically, the tumour was characterized by cellular pseudolobules composed of a disorderly admixture of collagen-producing fibroblasts and lipid rich lutein cells with shrunken nuclei. In one case the lutein cells had a robust appearance with abundant cytoplasm and vesicular nuclei. The pseudolobules were very vascular and separated by hypocellular dense to oedematous fibrous tissue. Frozen section demonstrated fat in luteinized cells in 3 cases.
Pai
Radha Ramachandra
RR
Department of Pathology, Kasturba Medical College, Mangalore, Karnataka.
Shaktawat
Sameer Singh
SS
Khadilkar
Urmila Niranjan
UN
Lobo
Flora Dorothy
FD
Rao
Vatsala Srinivas
VS
Philipose
Reba
R
D000328:Adult; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D010053:Ovary / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*