title: Carotid black blood MRI burden of atherosclerotic disease assessment correlates with ultrasound intima-media thickness.
abstract: The aim of this study was to correlate carotid black blood MRI based measurements with those obtained by ultrasound intima-media thickness (IMT). Seventeen patients with intermediate to high Framingham cardiovascular risk score underwent both carotid ultrasound and rapid extended coverage double inversion recovery black blood carotid MRI. Overall, there was good correlation between wall area, wall thickness, and plaque index measured by MRI and the IMT measurements obtained from the ultrasound images (max r2 = 0.72, p < 0.05). Patients with mean IMT > or = 1.2 mm had significantly higher values of wall area, plaque index and wall thickness compared to patients with mean IMT < 1.2 mm. Vessel wall measurements assessed by black-blood MRI may be potentially used clinically to evaluate plaque progression and regression.
authors.affiliation: Imaging Science Laboratories, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Mani
authors.forename: Silvia H
authors.initials: SH
authors.lastname: Aguiar
authors.forename: Vitalii V
authors.initials: VV
authors.lastname: Itskovich
authors.forename: Karen B
authors.initials: KB
authors.lastname: Weinshelbaum
authors.forename: John E
authors.initials: JE
authors.lastname: Postley
authors.forename: Erika J
authors.initials: EJ
authors.lastname: Wasenda
authors.forename: Juan Gilberto S
authors.initials: JG
authors.lastname: Aguinaldo
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Samber
authors.forename: Zahi A
authors.initials: ZA
authors.lastname: Fayad
mesh_terms: D000368:Aged; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000473:pathology*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D018570:Risk Assessment; D012307:Risk Factors; D018709:Statistics, Nonparametric; D017539:Tunica Intima / Q000000981:diagnostic imaging* / Q000473:pathology; D017540:Tunica Media / Q000000981:diagnostic imaging* / Q000473:pathology; D014463:Ultrasonography