title: [Effects of osteoporosis on experimental tooth movement in aged rats].
abstract: OBJECTIVE
  To examine the experimental tooth movement and recruitment of new osteoclasts in aged variotomized (OVX) rats.
  
  
  METHODS
  Eighty-two 3-month female virgin health rats were divided into two groups. Each group was divided into seven sub-groups of tooth movement: 0,1,3,5,7,10 and 14 days. The tooth movement and the population of osteoclasts were measured and comparatively analyzed.
  
  
  RESULTS
  The osteoporosis rats showed larger and faster tooth movement (P<0.05). In the osteoporosis group, the instantaneous tooth movement lasted longer time and traversed larger distance, the delay period was shorter, the population of osteoclasts was larger and displayed a faster recruitment.
  
  
  CONCLUSIONS
  These findings indicate that osteoporosis accelerates tooth movement in aged OVX rats.
authors.affiliation: Department of Orthodontics, West China Stomatological Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Tan
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Zhi-he
authors.initials: ZH
authors.lastname: Zhao
authors.forename: Ling-yong
authors.initials: LY
authors.lastname: Jiang
authors.forename: Rui
authors.initials: R
authors.lastname: Zou
mesh_terms: D000375:Aging; D000818:Animals; D002452:Cell Count; D005260:Female; D009967:Orthodontic Appliances; D010010:Osteoclasts / Q000166:cytology*; D010024:Osteoporosis / Q000209:etiology / Q000503:physiopathology*; D010052:Ovariectomy; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D014087:Tooth Movement Techniques