title: Successful recovery of acute hemosiderotic heart failure in beta-thalassemia major treated with a combined regimen of desferrioxamine and deferiprone.
abstract: We report the case of a 25-years-old male with beta-thalassemia major who developed acute heart failure, with severe systolic dysfunction, resulting from iron overload. Combined iron chelation with desferrioxamine and deferiprone together with standard cardiological treatment induced prompt and complete restoration of the cardiac function.
authors.affiliation: Gruppo Operativo di Cura delle Anemie Congenite, OspedaleSan Gerardo, Monza, Italy. luisatave@virgilio.it
authors.forename: Luisa
authors.initials: L
authors.lastname: Tavecchia
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Masera
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Russo
authors.forename: Antonio
authors.initials: A
authors.lastname: Cirò
authors.forename: Antonella
authors.initials: A
authors.lastname: Vincenzi
authors.forename: Chiara
authors.initials: C
authors.lastname: Vimercati
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Masera
mesh_terms: D000328:Adult; D000077543:Deferiprone; D003676:Deferoxamine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000209:etiology*; D006486:Hemosiderosis / Q000150:complications*; D006801:Humans; D007502:Iron Chelating Agents / Q000627:therapeutic use*; D008297:Male; D011728:Pyridones / Q000627:therapeutic use*; D016896:Treatment Outcome; D017086:beta-Thalassemia / Q000150:complications / Q000188:drug therapy*
chemical_list: D007502:Iron Chelating Agents; D011728:Pyridones; D000077543:Deferiprone; D003676:Deferoxamine