title: Successful treatment of a therapy-resistant pyogenic granuloma with topical imiquimod 5% cream.
abstract: A 58-year-old man was referred to our department for evaluation and treatment of a therapy-resistant pyogenic granuloma on his right third digit. This biopsy-confirmed lesion was unsuccessfully treated with shave excision and base electrocautery on two separate occasions before the patient presented to our clinic. After completing a 14-week course of twice-weekly imiquimod 5% topical application, this patient's pyogenic granuloma completely resolved. A satisfactory cosmetic outcome was also achieved, with virtually no scarring.
authors.affiliation: Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA. ggoldenb@wfubmc.edu
authors.forename: Gary
authors.initials: G
authors.lastname: Goldenberg
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Krowchuk
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Jorizzo
mesh_terms: D000279:Administration, Cutaneous; D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005385:Fingers / Q000473:pathology; D017789:Granuloma, Pyogenic / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod