Biomonitoring of exposure in farmworker studies.
Although biomonitoring has been used in many occupational and environmental health and exposure studies, we are only beginning to understand the complexities and uncertainties involved with the biomonitoring process--from study design, to sample collection, to chemical analysis--and with interpreting the resulting data. We present an overview of concepts that should be considered when using biomonitoring or biomonitoring data, assess the current status of biomonitoring, and detail potential advancements in the field that may improve our ability to both collect and interpret biomonitoring data. We discuss issues such as the appropriateness of biomonitoring for a given study, the sampling time frame, temporal variability in biological measurements to nonpersistent chemicals, and the complex issues surrounding data interpretation. In addition, we provide recommendations to improve the utility of biomonitoring in farmworker studies.
Barr
Dana B
DB
National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. dbarr@cdc.gov
Thomas
Kent
K
Curwin
Brian
B
Landsittel
Doug
D
Raymer
James
J
Lu
Chensheng
C
Donnelly
K C
KC
Acquavella
John
J
D000383:Agriculture; D004784:Environmental Monitoring; D006801:Humans; D010575:Pesticides / Q000493:pharmacokinetics* / Q000633:toxicity*; D012867:Skin / Q000378:metabolism
D010575:Pesticides