Treatment of stage IV malignant rhabdoid tumor of the kidney (MRTK) with ICE and VDCy: a case report.
The prognosis of stage IV malignant rhabdoid tumor of the kidney (MRTK) has been extremely poor. However, a combination of ICE (ifosfamide, carboplatin, and etoposide) and VDCy (vincristine, doxorubicin, and cyclophosphamide) was recently reported to be effective for metastatic MRTK. We describe a 21-month-old girl with stage IV MRTK who was successfully treated with ICE, VDCy, and radiotherapy. She remained well, without recurrence, 24 months after diagnosis. Alternating therapy with ICE and VDCy might become a standard regimen for stage IV MRTK, although further study is required to confirm its effectiveness.
Yamamoto
Masaki
M
Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan. ymasaki@sapmed.ac.jp
Suzuki
Nobuhiro
N
Hatakeyama
Naoki
N
Mizue
Nobuo
N
Hori
Tsukasa
T
Kuroiwa
Yuki
Y
Hareyama
Masato
M
Oda
Takanori
T
Kudoh
Tooru
T
Nui
Akihiro
A
Matsuno
Takashi
T
Hirama
Toshinori
T
Yokoyama
Shigeaki
S
Dome
Jeffrey S
JS
Tsutsumi
Hiroyuki
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007223:Infant; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D012074:Remission Induction / Q000379:methods; D018335:Rhabdoid Tumor / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D007069:Ifosfamide