title: A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis.
abstract: Here, we describe a case of severe pancreatitis in overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in an adult female patient. Treatment with plasmapheresis and high-dose prednisone successfully saved her life and led to remission of the pancreatitis. This is the first case report of severe acute pancreatitis in the setting of overlap syndrome of SLE and SSc. The advantages and disadvantages of the use of corticosteroids are discussed.
authors.affiliation: Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.
authors.forename: Yukie
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okamoto
authors.forename: Kyoko
authors.initials: K
authors.lastname: Koizumi
authors.forename: Mutsuto
authors.initials: M
authors.lastname: Tateishi
authors.forename: Masako
authors.initials: M
authors.lastname: Hara
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kamatani
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D016670:Gabexate / Q000008:administration & dosage; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects; D010195:Pancreatitis / Q000209:etiology / Q000628:therapy; D010956:Plasmapheresis / Q000379:methods*; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D012595:Scleroderma, Systemic / Q000150:complications*; D015842:Serine Proteinase Inhibitors / Q000008:administration & dosage; D013577:Syndrome
chemical_list: D000893:Anti-Inflammatory Agents; D015842:Serine Proteinase Inhibitors; D016670:Gabexate; D011241:Prednisone; D008775:Methylprednisolone