Antioxidant activity with flavonoidal constituents from Aerva persica.
A new flavanone Persinol (1) and the new flavanone glucosides persinosides A (2) and B (3), along with known flavonoids (4 and 5) have been isolated from the ethyl acetate soluble fraction of the whole plants of Aerva persica. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1D and 2D-NMR) spectral data. All of them showed profound antioxidative activities by DPPH and cytochrome-c-reduction assays using the HL-60 cell culture system.
Ahmed
Ejaz
E
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Imran
Muhammad
M
Malik
Abdul
A
Ashraf
Muhammad
M
D027703:Amaranthaceae / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D001713:Biphenyl Compounds; D045304:Cytochromes c / Q000378:metabolism; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000378:metabolism; D005609:Free Radicals / Q000378:metabolism; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D018922:HL-60 Cells; D006801:Humans; D006834:Hydrazines; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010154:Pakistan; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry; D013329:Structure-Activity Relationship
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D005609:Free Radicals; D005960:Glucosides; D006834:Hydrazines; D010851:Picrates; D010936:Plant Extracts; D045304:Cytochromes c; C004931:1,1-diphenyl-2-picrylhydrazyl