Relapse of stage I small cell lung cancer ten or more years after the start of treatment.
Most patients with small cell lung cancer (SCLC) usually show relapse within 1 or 2 years. Relapses after a 5-year disease-free survival are extremely rare. This report describes two patients with stage I SCLC in whom the disease recurred 10 or more years after the start of initial therapy. Because the recurrence of SCLC was noted in the mediastinal lymph nodes of the same side, we concluded that the patients had a late relapse of SCLC rather than a metachronous lung cancer.
Matsui
Kaoru
K
Department of Thoracic Malignancy, Medical Center for Respiratory and Allergic Diseases of Osaka Prefecture, Osaka 583-8588, Japan. kmatsui@hbk.pref.osaka.jp
Sawa
Toshiyuki
T
Suzuki
Hidekazu
H
Nakagawa
Katsuhiro
K
Okamoto
Norio
N
Tada
Takuhito
T
Nagano
Teruaki
T
Masuda
Noriyuki
N
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000556:secondary; D018288:Carcinoma, Small Cell / Q000556:secondary / Q000628:therapy*; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000628:therapy*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary