General synthesis for chiral 4-alkyl-4-hydroxycyclohexenones.
[reaction: see text] Some selective transformations of resorcinol-derived cyclohexadienone are reported. Efforts led to a structure reported to display anticancer properties. On the basis of the results, the structures for natural products reported to contain a 4,6-dihydroxy-4-alkyl-cyclohexenone nucleus are corrected.
Hoarau
Christophe
C
Department of Chemistry and Biochemistry, University of California at Santa Barbara, 93106-9510, USA.
Pettus
Thomas R R
TR
D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D027926:Anacardiaceae / Q000737:chemistry; D002384:Catalysis; D003512:Cyclohexanones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism
D000473:Alkanes; D003512:Cyclohexanones