[Treatment of deep partial thickness burns by a single dressing of porcine acellular dermal matrix].
OBJECTIVE
To explore the effect of one dressing of porcine acellular dermal matrix on deep partial thickness burns.


METHODS
From January 1997 to January 2004, sixty-seven cases of deep partial thickness total burned surface area (TBSA) from 50% to 90% burn wound were treated by a single dressing of porcine acellular dermal matrix (the porcine acellular dermal matrix group). Ten cases of deep partial thickness burned patients with the same TBSA treated by exposure method served as the exposure method group. The healing time of the wound was observed. The patients were followed up for 3 months to 2 years, and the scar proliferation was observed.


RESULTS
The deep partial-thickness wound would be healed without dressing change in the porcine acellular dermal matrix group, and the average healing time was (12.2 +/- 2.6) days. The average healing time of the exposure method group was (27.4 +/- 3.5) days. Follow up of the patients within 3 months to 2 years showed that scar proliferation in the porcine acellular dermal matrix group was much less than that in the exposure method group, even no scar proliferation was observed in some patients.


CONCLUSIONS
Without tangential excision, autografting and dressing change, a single dressing of porcine acellular dermal matrix on deep partial thickness burn wound could shorten the healing time and inhibit scar proliferation.
Feng
Xiang-sheng
XS
Department of Burns, the First People's Hospital of Foshan, Foshan 528000, China. fxsheng@fsyyy.com
Pan
Yin-gen
YG
Tan
Jia-ju
JJ
Wu
Qiu-he
QH
Shen
Rui
R
Ruan
Shu-bin
SB
Chen
Xiao-dong
XD
Zhang
Feng-gang
FG
Lin
Ze-peng
ZP
Du
Yong-jun
YJ
D000818:Animals; D001684:Biological Dressings; D002056:Burns / Q000473:pathology / Q000628:therapy*; D002921:Cicatrix / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013552:Swine; D016896:Treatment Outcome; D014945:Wound Healing