title: Left ventricular papillary muscle mass: relationship to left ventricular mass and volumes by magnetic resonance imaging.
abstract: OBJECTIVE
  To evaluate the effect of papillary muscle mass on the calculation of left ventricular (LV) function and mass and to determine the relationship between papillary muscle mass with body size and sex.
  
  
  METHODS
  Cardiac magnetic resonance imaging examinations from 50 men and 50 women were randomly selected from the Multi-Ethnic Study of Atherosclerosis database. The contours of the papillary muscles were traced manually, and the LV wall contours were outlined semiautomatically based on short-axis images. Papillary muscle mass, LV mass, and volumes were calculated.
  
  
  RESULTS
  Inclusion of the papillary muscles results in significantly higher total LV mass values (P<0.001) and lower end-diastolic volume values (P<0.001) compared with measurements excluding papillary muscles from the LV mass. Papillary muscle mass accounts for 8.9% of the total LV mass and is correlated with LV wall mass (r=0.81, P<0.001).
  
  
  CONCLUSIONS
  Papillary muscle mass significantly affects LV volumes and mass determined by cine magnetic resonance imaging.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
authors.forename: Jens
authors.initials: J
authors.lastname: Vogel-Claussen
authors.forename: J Paul
authors.initials: JP
authors.lastname: Finn
authors.forename: Antoinette S
authors.initials: AS
authors.lastname: Gomes
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Hundley
authors.forename: Michael
authors.initials: M
authors.lastname: Jerosch-Herold
authors.forename: Gregory
authors.initials: G
authors.lastname: Pearson
authors.forename: Shantanu
authors.initials: S
authors.lastname: Sinha
authors.forename: João A C
authors.initials: JA
authors.lastname: Lima
authors.forename: David A
authors.initials: DA
authors.lastname: Bluemke
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D010210:Papillary Muscles / Q000033:anatomy & histology*; D016277:Ventricular Function, Left / Q000502:physiology*