[Severe Graves' ophthalmopathy accompanied by myasthenia gravis].
We report a 53-year-old woman with severe Graves' ophthalmopathy accompanied by uncontrolled myasthenia gravis. She presented remarkable exophthalmos, chemosis, and restriction of eye movement. Despite plasma exchange, steroid pulse therapy, local injection of steroid, and irradiation, ocular symptoms did not ameliorate. Since optic neuropathy was seen, orbital decompression surgery was performed in the left eye. Bilateral chemosis was improved after the surgery. Five years after surgery, there was no ocular palsy in the operated left eye, but in the contralateral eye. For the good prognosis of the eye movement, orbital decompression might be recommended in the severe Graves' ophthalmopathy accompanied by the optic neuropathy and/or ophthalmoplegia with proptosis.
Maeda
Kengo
K
Division of Neurology, Department of Medicine, Shiga University of Medical Science.
Kume
Shinji
S
Nishio
Yoshihiko
Y
Maeda
Shiro
S
Nishida
Yasuhiro
Y
Suzuki
Mikio
M
Nakaguchi
Takahiro
T
Kawabata
Toru
T
Hashimoto
Osamu
O
Hisanaga
Takashi
T
Kashiwagi
Atsunori
A
Yasuda
Hitoshi
H
D019299:Decompression, Surgical; D005260:Female; D049970:Graves Ophthalmopathy / Q000150:complications* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000601:surgery; D009901:Optic Nerve Diseases / Q000150:complications / Q000601:surgery; D010951:Plasma Exchange; D012720:Severity of Illness Index; D016896:Treatment Outcome