Bronchogenic squamous cell carcinoma presenting as cicatrizing conjunctivitis.
OBJECTIVE
To report a case of cicatrizing conjunctivitis as the initial manifestation of a bronchogenic squamous cell carcinoma.


METHODS
Case report of a 57-year-old patient with bilateral history of ocular pain, redness, and discharge, with no apparent predisposing factors. Examination revealed chemosis, pseudomembrane, and symblepharon formation, and multiple ulcerated pustular and vesicular periocular and perioral lesions literature review.


RESULTS
Skin biopsy was compatible with bullous pemphigoid. Two months later he developed respiratory symptoms, and a squamous cell carcinoma was diagnosed.


CONCLUSIONS
This case demonstrates cicatrizing conjunctivitis as a possible paraneoplastic syndrome associated with squamous cell lung carcinoma.
Vroman
David T
DT
Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC 29425, USA. vromandt@musc.edu
Breckenridge
Rebecca Reid
RR
Solomon
Kerry D
KD
Sandoval
Helga P
HP
Fernández de Castro
Luis E
LE
D002283:Carcinoma, Bronchogenic / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003231:Conjunctivitis / Q000175:diagnosis*; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D010390:Pemphigoid, Benign Mucous Membrane / Q000175:diagnosis*