title: Steroidal alkaloids from bulbs of Fritillaria lichuanensis.
abstract: A new steroidal alkaloid, hupehenizioiside (1), together with four known steroidal alkaloids hupehenizine (2), hupehenirine (3), peiminine (4) and hupeheninoside (5), were isolated and identified from the bulbs of Fritillaria lichuanensis. The structure of hupehenizioiside (1) was determined to be (20R,25S)-5alpha,14alpha,17beta-cevanine-6-oxo-3beta-O-beta-D-glucoside by spectral analysis and chemical evidence. Compounds (2)-(5) were isolated from Fritillaria lichuanensis for the first time.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
authors.forename: Hui-Fang
authors.initials: HF
authors.lastname: Pi
authors.forename: Han-Li
authors.initials: HL
authors.lastname: Ruan
authors.forename: Yong-Hui
authors.initials: YH
authors.lastname: Zhang
authors.forename: Lei-Ming
authors.initials: LM
authors.lastname: Niu
authors.forename: Ji-Zhou
authors.initials: JZ
authors.lastname: Wu
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D002595:Cevanes / Q000737:chemistry; D031410:Fritillaria; D005960:Glucosides / Q000737:chemistry; D015394:Molecular Structure; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D000470:Alkaloids; D002595:Cevanes; D005960:Glucosides; D013256:Steroids; C511966:hupehenirine; C511967:hupehenizine; C511965:hupehenizioiside; C047384:hupeheninoside; C047331:peiminine