The exanthem of acute pulmonary coccidioidomycosis: Clinical and histopathologic features of 3 cases and review of the literature.
BACKGROUND
Coccidioidomycosis may be associated with a reactive generalized cutaneous eruption early in the course of the illness. Detailed descriptions in the literature are scarce.


METHODS
We describe 3 patients with a florid eruption associated with pulmonary coccidioidomycosis. The exanthem mimicked erythema multiforme clinically but not histologically. In 2 of the patients, the eruption began before the presence of detectable antibodies in the serum.


CONCLUSIONS
The presence of the exanthem, in combination with fever and/or pneumonia, was a helpful clue to the diagnosis of coccidioidomycosis.
DiCaudo
David J
DJ
Department of Dermatology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA. dicaudo.david@mayo.edu
Yiannias
James A
JA
Laman
Susan D
SD
Warschaw
Karen E
KE
D000208:Acute Disease; D000368:Aged; D003047:Coccidioidomycosis / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged