Gastric syphilis mimicking adenocarcinoma: a case report.
Syphilis is an unexpected diagnosis in the stomach, and the reduced incidence of syphilis has made its clinical presentation less widely appreciated. We report a 43-yr-old man suffering from epigastric tenderness with an initial diagnosis of gastric carcinoma; gastric syphilis was confirmed by demonstrating spirochetes in a gastric biopsy specimen by silver impregnation. Excessive lymphoplasmacytic infiltration with diffuse thickening of gastric rugae should raise suspicion of gastric syphilis, which should be considered in the differential diagnosis of diffuse erosive gastritis and infiltrative lesions of the stomach.
Choi
Yoon-La
YL
Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Han
Jae Joon
JJ
Lee
Da Keun
DK
Cho
Min Ho
MH
Kwon
Ghee Young
GY
Ko
Young Hyeh
YH
Park
Cheol Keun
CK
Ahn
Geunghwan
G
D000230:Adenocarcinoma / Q000175:diagnosis*; D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D016508:Fluorescent Treponemal Antibody-Absorption Test; D006801:Humans; D008297:Male; D013270:Stomach / Q000382:microbiology; D013272:Stomach Diseases / Q000175:diagnosis* / Q000382:microbiology; D013274:Stomach Neoplasms / Q000175:diagnosis*; D013587:Syphilis / Q000175:diagnosis*