Cu-catalyzed cross-dehydrogenative coupling: a versatile strategy for C-C bond formations via the oxidative activation of sp(3) C-H bonds.
Cu-catalyzed cross-dehydrogenative coupling (CDC) methodologies were developed based on the oxidative activation of sp(3) C-H bonds adjacent to a nitrogen atom. Various sp, sp(2), and sp(3) C-H bonds of pronucleophiles were used in the Cu-catalyzed CDC reactions. Based on these results, the mechanisms of the CDC reactions also are discussed.
Li
Zhiping
Z
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC, Canada H3A 2K6.
Bohle
D Scott
DS
Li
Chao-Jun
CJ
D002244:Carbon / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D044005:Tetrahydroisoquinolines / Q000737:chemistry
D044005:Tetrahydroisoquinolines; D002244:Carbon; D003300:Copper; D006859:Hydrogen