title: Quantitative calcaneal ultrasonometry: normative data and age-related changes for stiffness index in the Turkish population.
abstract: The aim of this cross-sectional study was to define the normative data for stiffness index in a large sample of Turkish population and to clarify sex differences as well as age-related changes. A total of 10,435 subjects (aged 18-89 yr) were screened with calcaneal ultrasound and were requested to complete a detailed questionnaire listing all important risk factors, diseases, and treatments affecting bone metabolism. To be included in the study, subjects had to be free of any disease and any medical treatment known to affect bone metabolism. A total of 8,156 subjects (1,389 males and 6,767 females) were included in the study. Normative data was expressed using two statistical models including mean and 95th percentile, and regression analysis. The mean value of stiffness index in females peaked in the third decade, whereas in males it peaked in the age group of 18-29 yr. The stiffness index of females decreased by 24.26%. The total age-related decrease was 17.8% for stiffness index in the males. Stiffness index in males was a function of age (negatively) and body mass index (positively). Stiffness index in females was a function of age (negatively) and weight (positively). The results of this study could be useful as a guide for comparing the data of individual studies and may serve as reference normative data for the Turkish population.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Ege, Izmir. berrin.durmaz@ege.edu.tr
authors.forename: Berrin
authors.initials: B
authors.lastname: Durmaz
authors.forename: Sema
authors.initials: S
authors.lastname: Oncel
authors.forename: Yesim
authors.initials: Y
authors.lastname: Kirazli
authors.forename: Serap
authors.initials: S
authors.lastname: Alper
authors.forename: Ozlen
authors.initials: O
authors.lastname: Peker
authors.forename: Merih
authors.initials: M
authors.lastname: Saridogan
authors.forename: Yesim Gokce
authors.initials: YG
authors.lastname: Kutsal
authors.forename: Gulay
authors.initials: G
authors.lastname: Dinçer
authors.forename: Fatma
authors.initials: F
authors.lastname: Atalay
authors.forename: Nurten
authors.initials: N
authors.lastname: Eskiyurt
authors.lastname: Turkish Osteoporosis Society
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D002111:Calcaneus / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis; D012016:Reference Values; D012737:Sex Factors; D014421:Turkey; D014463:Ultrasonography