Siamenols A-D, four new coumarins from Mammea siamensis.
Further investigation of the dichloromethane extract of the twigs of Mammea siamensis led to the isolation of four novel coumarins, named siamenols A-D (1-4) together with three known xanthones. The structures of the new coumarins were elucidated by spectroscopic analysis, including 2D NMR spectroscopic data. In addition, the absolute stereochemistry of hydroxyl group of siamenol C (3) was determined to be S configuration by using modified Mosher's method.
Prachyawarakorn
Vilailak
V
Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok 10210, Thailand.
Mahidol
Chulabhorn
C
Ruchirawat
Somsak
S
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology; D001685:Biological Factors / Q000737:chemistry / Q000302:isolation & purification; D002227:Carbazoles / Q000737:chemistry* / Q000302:isolation & purification; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D031252:Mammea / Q000737:chemistry*; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D013237:Stereoisomerism; D044004:Xanthones / Q000302:isolation & purification
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001685:Biological Factors; D002227:Carbazoles; D003374:Coumarins; D044004:Xanthones; C408013:siamenol