Autoimmune hypothyroidism after unrelated haematopoietic stem cell transplantation in children.
We describe two pediatric patients who developed autoimmune hypothyroidism 2 years after unrelated allogeneic hematopoietic stem cell transplantation. The causes of post-transplantation autoimmune hypothyroidism are probably multiple. In these two patients, the presence of chronic graft-versus-host disease may be the most significant contributing factor.
Lee
Vincent
V
Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong. levin@cuhk.edu.hk
Cheng
Pik Shun
PS
Chik
Ki Wai
KW
Wong
Gary W K
GW
Shing
Matthew M K
MM
Li
Chi Kong
CK
D001327:Autoimmune Diseases / Q000175:diagnosis / Q000209:etiology*; D002648:Child; D002908:Chronic Disease; D006086:Graft vs Host Disease / Q000150:complications; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D007223:Infant; D008297:Male; D014184:Transplantation, Homologous