Coexistent B-cell lymphoma and cutaneous T-cell lymphoma.
A 78-year-old man with a history of mycosis fungoides was referred for evaluation of a right adrenal mass. A physical examination showed the left cervical lymph node to be palpable, which was later shown to be caused by a diffuse large B-cell lymphoma. The patient was diagnosed with concurrent mycosis fungoides and a diffuse large B-cell lymphoma. Three courses of chemotherapy were performed, however, the patient died of advanced disease. Autopsy findings showed that the right adrenal and soft tissue masses had an identical B-cell origin. Although the exact mechanism remains unclear, the pathogenesis of this rare association is discussed.
Inokuchi
Taku
T
Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
Shincho
Mayumi
M
Moriwaki
Yuji
Y
Ka
Tsuneyoshi
T
Takahashi
Sumio
S
Tsutsumi
Zenta
Z
Lin
Yoshiaki
Y
Hirota
Seiichi
S
Yamamoto
Tetsuya
T
D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D009182:Mycosis Fungoides / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000188:drug therapy; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide