Longifoside-A and -B: two new cerebrosides from Mentha longifolia (Lamiaceae).
Two new N-acyl-glycosphingosines (cerebrosides) named longifoside-A {6'-tetracosenamide, N-[3,4-dihydroxy-1-(hydroxymethyl)-2-(beta-D-glucopyranosyl) heptadecyl]-(6'E)} and B {6'-tetracosenamide, N-[3-hydroxy-1-(hydroxymethyl)-2-(beta-D-glucopyranosyl)-4Z-heptadecenyl]-(6'E)} have been obtained from the methanolic extract of Mentha longifolia belonging to the family Lamiaceae. Both the cerebrosides were purified as their acetate-derivatives: 6'-tetracosenamide, N-[3,4-diacetoxy-1-(acetoxymethyl)-2-(tetraacetoxy-beta-D-glucopyranosyl) heptadecyl]-(6'E) and 6'-tetracosenamide, N-[3-acetoxy-1-(acetoxymethyl)-2-(tetraacetoxy-beta-D-glucopyranosyl)-4Z-heptadecenyl]-(6'E). They were characterized with the aid of 1D and sophisticated 2D-NMR spectroscopic techniques.
Shaiq Ali
Muhammad
M
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi - 75270, Pakistan. shaiq303@super.net.pk
Ahmed
Waqar
W
Saleem
Muhammad
M
Ashfaq Ali
Mohammad
M
D002554:Cerebrosides / Q000737:chemistry / Q000302:isolation & purification*; D005963:Glucosylceramides / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D027541:Mentha / Q000737:chemistry*; D015394:Molecular Structure
D002554:Cerebrosides; D005963:Glucosylceramides; C513840:N-(3,4-dihydroxy-1-(hydroxymethyl)-2-glucopyranosylheptadecyl)-6'-tetracosenamide; C513841:N-(3-hydroxy-1-(hydroxymethyl)-2-glucopyranosyl-4-heptadecenyl)-6'-tetracosenamide