title: Isolation of Lawsonia intracellularis in Korea and reproduction of proliferative enteropathy in pigs and hamsters.
abstract: Lawsonia intracellularis (L. intracellularis) was isolated from a Korean pig suffering acute proliferative enteropathy. In vitro culture conditions of L. intracellularis were established in McCoy cells. Pigs and hamsters experimentally infected with the pure culture of L. intracellularis reproduced clinical signs and intestinal lesions of proliferative enteropathy. The presence of L. intracellularis in the intestinal lesions was confirmed by immunohistochemistry with L. intracellularis-specific monoclonal antibodies.
authors.affiliation: National Veterinary Research and Quarantine Service, Seoul, Korea.
authors.forename: Jung-Yong
authors.initials: JY
authors.lastname: Yeh
authors.forename: Tae-Jong
authors.initials: TJ
authors.lastname: Kim
authors.forename: Seung-Yong
authors.initials: SY
authors.lastname: Park
authors.forename: Chang-Seon
authors.initials: CS
authors.lastname: Song
authors.forename: Yong-Dhuk
authors.initials: YD
authors.lastname: Yoon
authors.forename: Soo-Ki
authors.initials: SK
authors.lastname: Kim
authors.forename: Joong-Bok
authors.initials: JB
authors.lastname: Lee
authors.forename: In-Soo
authors.initials: IS
authors.lastname: Choi
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D006224:Cricetinae; D045824:Desulfovibrionaceae Infections / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D007082:Ileum; D007150:Immunohistochemistry / Q000662:veterinary; D007410:Intestinal Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D007413:Intestinal Mucosa / Q000382:microbiology; D007723:Korea; D020639:Lawsonia Bacteria / Q000302:isolation & purification* / Q000472:pathogenicity*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal