Secondary assembly of bile salts mediated by beta-cyclodextrin-terbium(III) complex.
A fluorescent cyclodextrin-Tb(III) complex is successfully synthesized and can include bile salts in its hydrophobic cavities. Therefore, it can efficiently induce the secondary assembly of small bile salt primary micelles to large micelle aggregates, and the aggregation process can be easily observed by transmission electron microscopy (TEM) and fluorescence microscopy.
Liu
Yu
Y
Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, PR China. yuliu@nankai.edu.cn
Zhang
Ning
N
Chen
Yong
Y
Chen
Guo-Song
GS
D001647:Bile Acids and Salts / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003840:Deoxycholic Acid / Q000737:chemistry; D005456:Fluorescent Dyes; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D013725:Terbium / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
D001647:Bile Acids and Salts; D005456:Fluorescent Dyes; D008823:Micelles; D047392:beta-Cyclodextrins; D003840:Deoxycholic Acid; D013725:Terbium