Reduced fluorescence quenching of cyclodextrin-acetylene dye rotaxanes.
An acetylene dye rotaxane with alpha-CD has been synthesized using the Heck-Cassar-Sonogashira-Hagihara-type reaction in aqueous solution. Free dye with tetracarboxylic acids is found to be highly sensitive to various metal ions, showing high Stern-Volmer constants, KSV. As CD encapsulation protects and stabilizes the threaded chromophore against an outside quencher, metal-insensitive biological tags are an obvious application for this class of molecules.
Park
Jong S
JS
School of Polymer, Textile and Fiber Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.
Wilson
James N
JN
Hardcastle
Kenneth I
KI
Bunz
Uwe H F
UH
Srinivasarao
Mohan
M