title: Septal lines in pleural inflammation: multidetector computed tomography findings in 30 patients.
abstract: OBJECTIVE
  The aim of the study was to evaluate the interstitial changes adjacent to pleural inflammation on multidetector computed tomography.
  
  
  METHODS
  The multidetector computed tomography scans of 30 patients with pleural inflammation were retrospectively and blindly evaluated by 2 observers. A control group of 7 patients with documented fibrothorax was also included. The number, appearance, thickness, and extent of septal lines were analyzed.
  
  
  RESULTS
  More than 10 septal lines immediately adjacent to the abnormal pleura were seen in 22 of the 30 patients with pleural inflammation and 2 of the 7 patients with fibrothorax (P<0.01). Septal lines that are more than 1 mm thick were seen in 13 of the 30 patients with acute inflammation and none of the patients with fibrothorax (P<0.01). Differences between focal and diffuse pleural inflammation included 10 cm or greater craniocaudal extent and more smooth septal lines with diffuse pleural inflammation.
  
  
  CONCLUSIONS
  Pleural inflammation is associated with increased number and thickening of septal lines in the immediately adjacent lung parenchyma.
authors.affiliation: Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Dodd
authors.forename: Carolina A
authors.initials: CA
authors.lastname: Souza
authors.forename: Nestor L
authors.initials: NL
authors.lastname: Müller
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010994:Pleura / Q000000981:diagnostic imaging; D010998:Pleurisy / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*