title: Clinical application of rapid serial fourier-domain optical coherence tomography for macular imaging.
abstract: OBJECTIVE
  To introduce and examine the utility of a retinal imaging technique using high-speed optical coherence tomography (OCT) for creating a more complete retinal structural map to aid in the evaluation of patients with macular pathology.
  
  
  METHODS
  Prospective observational case series.
  
  
  METHODS
  Five patients with a variety of macular pathologies.
  
  
  METHODS
  Patients were imaged with a Fourier-domain high-speed high-resolution OCT system built at our institution. A sweeping serial OCT B-scan of the macula was acquired to create a detailed retinal structural map. The data were then used to make individual clinical observations.
  
  
  RESULTS
  Rapid serial OCT B-scans produced detailed macular maps for all 5 patients. Diagnoses of imaged patients included macular hole, lamellar macular hole, regressed macular hole or macular microhole, choroidal neovascular membrane (CNV) from age-related macular degeneration, and CNV from presumed ocular histoplasmosis syndrome. Reconstructed B-scans and C-scans are shown for selected patients to illustrate the additional perspectives gained by obtaining a detailed retinal map.
  
  
  CONCLUSIONS
  Rapid serial Fourier-domain OCT B-scanning can be used to create a detailed retinal structural map. This technique provides additional information that can be missed on single OCT images and provides an accurate way to image large or complex lesions, and allows B-scan and C-scan reconstructions to be made that provide additional perspectives into retinal structures that may be missed using traditional imaging methods.
authors.affiliation: Department of Ophthalmology & Vision Science, University of California-Davis, Sacramento, California 95817, USA.
authors.forename: Suhail
authors.initials: S
authors.lastname: Alam
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Zawadzki
authors.forename: Stacey
authors.initials: S
authors.lastname: Choi
authors.forename: Christina
authors.initials: C
authors.lastname: Gerth
authors.forename: Susanna S
authors.initials: SS
authors.lastname: Park
authors.forename: Lawrence
authors.initials: L
authors.lastname: Morse
authors.forename: John S
authors.initials: JS
authors.lastname: Werner
mesh_terms: D000328:Adult; D000368:Aged; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology; D005128:Eye Diseases / Q000150:complications; D005260:Female; D005583:Fourier Analysis; D006660:Histoplasmosis / Q000150:complications; D006801:Humans; D008266:Macula Lutea; D008297:Male; D011446:Prospective Studies; D012164:Retinal Diseases / Q000175:diagnosis*; D012167:Retinal Perforations / Q000175:diagnosis; D041623:Tomography, Optical Coherence