[Effects of osteoporosis on experimental tooth movement in aged rats].
OBJECTIVE
To examine the experimental tooth movement and recruitment of new osteoclasts in aged variotomized (OVX) rats.


METHODS
Eighty-two 3-month female virgin health rats were divided into two groups. Each group was divided into seven sub-groups of tooth movement: 0,1,3,5,7,10 and 14 days. The tooth movement and the population of osteoclasts were measured and comparatively analyzed.


RESULTS
The osteoporosis rats showed larger and faster tooth movement (P<0.05). In the osteoporosis group, the instantaneous tooth movement lasted longer time and traversed larger distance, the delay period was shorter, the population of osteoclasts was larger and displayed a faster recruitment.


CONCLUSIONS
These findings indicate that osteoporosis accelerates tooth movement in aged OVX rats.
Tan
Li-jun
LJ
Department of Orthodontics, West China Stomatological Hospital, Sichuan University, Chengdu 610041, China.
Wang
Jun
J
Zhao
Zhi-he
ZH
Jiang
Ling-yong
LY
Zou
Rui
R
D000375:Aging; D000818:Animals; D002452:Cell Count; D005260:Female; D009967:Orthodontic Appliances; D010010:Osteoclasts / Q000166:cytology*; D010024:Osteoporosis / Q000209:etiology / Q000503:physiopathology*; D010052:Ovariectomy; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D014087:Tooth Movement Techniques