[Glucose levels in non-diabetic patients. Is it a prognostic factor in acute coronary syndrome?].
BACKGROUND
The role of glucose elevation above levels considered normal in non- diabetic patients with acute coronary syndromes (ACS) is not adequately defined. The aim of this study was to determine the association between serum glucose at admission and 1-year mortality in this type of patients.


METHODS
We studied 648 non diabetic patients admitted consecutively with ACS. Serum glucose was determined at admission, together with classical risk factors, biochemical and inflammatory markers. The primary endpoint was all cause mortality at one year follow-up.


RESULTS
Patients with normal glucose had lower mortality than patients with impaired fasting glucose (14.1% vs 5.7% 1-year mortality) or with glucose levels in diabetic range (24.7% vs 5.7% 1-year mortality).


CONCLUSIONS
In non-ST elevation acute coronary syndromes, elevated levels of glucose in non-diabetic patients are strong predictors of all cause death at one year follow-up. This prognostic value is independent of other risk factors biochemical and inflammatory markers.
Fácila
L
L
Servicio de Cardiología, Consorcio Hospitalario Provincial de Castellón, Castellón, España. lfacila@hotmail.com
Bertomeu-González
V
V
Sanchís
J
J
Bodí
V
V
Núñez
J
J
Llácer
A
A
Bellido
V
V
D000208:Acute Disease; D000368:Aged; D000789:Angina, Unstable / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*; D011379:Prognosis; D013577:Syndrome
D001786:Blood Glucose