title: Enhancement of brain tumors in 0.23-T low-field MRI: comparison of edema attenuated inversion recovery (EDAIR) sequences with T1-weighted sequence.
abstract: OBJECTIVE
  The aim of this study is to explore whether edema attenuated inversion recovery (EDAIR) sequences could be used to improve tumor contrast in contrast-enhanced low-field 0.23-Tesla magnetic resonance imaging (MRI) using 0.1 mmol/kg of gadolinium-based contrast agent.
  
  
  METHODS
  Ten patients with brain tumors were examined by using the following contrast-enhanced sequences: T1-weighted spin echo, EDAIR with inversion time (TI) of 600 milliseconds, and EDAIR with TI of 800 milliseconds. Images were assessed both quantitatively and qualitatively.
  
  
  RESULTS
  Results suggest that tumor contrast enhancement in low-field MRI can be improved without increasing contrast agent dose. EDAIR 600 appears to be optimal in most cases.
  
  
  CONCLUSIONS
  This inversion recovery sequence could be applicable as an additional sequence in the imaging of metastases in low-field MRI, as well as imaging of any other enhancing brain tumors or lesions in low-field MRI.
authors.affiliation: Department of Diagnostic Radiology, Oulu University Hospital, P.O. Box 50, 90029 OYS, Oulu, Finland. salla.kokkonen@hexele.fi
authors.forename: Salla-Maarit
authors.initials: SM
authors.lastname: Kokkonen
authors.forename: Ari
authors.initials: A
authors.lastname: Karttunen
authors.forename: Pekka
authors.initials: P
authors.lastname: Jartti
authors.forename: Jani
authors.initials: J
authors.lastname: Katisko
authors.lastname: Phillic
authors.forename: Osmo
authors.initials: O
authors.lastname: Tervonen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D004487:Edema / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008280:Magnetics; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA