title: Improved multiplicity-editing of HMBC NMR spectra.
abstract: A new improved multiplicity-edited HMBC experiment is introduced that leads to better J cross-talk suppression in the even (i.e. C + CH2 groups) and odd (i.e. CH + CH3 groups) subspectra. By combining data recorded with three different pulse sequences J cross-talk becomes a second-order effect in Delta1J, i.e. the deviation of an actual 1J coupling constant from the value 1J0 used in setting delays tau = (1J0)(-1/2), which is adequate for most applications. As for the original multiplicity-edited HMBC experiment, the improved experiment can be performed with a single excitation delay or implemented in a broadband version similar to broadband HMBC.
authors.affiliation: Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Benie
authors.forename: Ole W
authors.initials: OW
authors.lastname: Sørensen