title: [A case of advanced gastric cancer successfully treated by TS-1 and CDDP after jejunostomy].
abstract: A 65-year-old female with unresectable advanced gastric cancer accompanied by multiple lung metastases underwent jejunostomy and was treated with TS-1 and CDDP. One course consisted of TS-1 (80 mg/day) via an intestinal fistula tube from days 1 to 14 followed by 14 days rest and CDDP (80 mg/day) was administered by 24-hour continuous intravenous infusion on day 8. After 3 courses, the primary tumor and lymph node metastases decreased in size (PR), and CT scan showed the multiple lung metastases had disappeared. Total gastrectomy (D 2) and splenectomy were performed after chemotherapy. The final diagnosis was Stage IIIA and the pathological response to chemotherapy was Grade 2. The patient has survived for over 14 months after surgery and has presented no signs of recurrence.
authors.affiliation: Dept. of Surgery, Nippon Medical School Chiba Hokuso Hospital.
authors.forename: Takashi
authors.initials: T
authors.lastname: Shirakawa
authors.forename: Noritake
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kimiyoshi
authors.initials: K
authors.lastname: Yokoi
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ishikawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Seya
authors.forename: Kouji
authors.initials: K
authors.lastname: Horiba
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamada
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Kanazawa
authors.forename: Keiichi
authors.initials: K
authors.lastname: Okawa
authors.forename: Masato
authors.initials: M
authors.lastname: Yoshioka
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Oaki
authors.forename: Akira
authors.initials: A
authors.lastname: Tokunaga
authors.forename: Takashi
authors.initials: T
authors.lastname: Tajiri
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007263:Infusions, Parenteral / Q000379:methods; D007582:Jejunostomy; D008175:Lung Neoplasms / Q000556:secondary; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D010094:Oxonic Acid / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D012074:Remission Induction; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin