title: Usefulness of pneumococcal antigen detection in pleural fluid samples by immunochromatographic assay for diagnosis of pneumococcal pneumonia.
abstract: This study investigated the utility of an immunochromatographic test (ICT) for the detection of Streptococcus pneumoniae antigens in pleural fluid. Antigen was detected in 15 of 19 (79%) patients with pneumococcal pneumonia. The ICT was always negative in patients with non-pneumococcal pneumonia, but was positive in three cases with a non-infectious aetiology. In patients with pneumonia for which no pathogen was identified, antigen was detected in one of 24 pleural fluids tested. The ICT can be a valuable tool for the management of pneumonia because it can detect pneumococcal antigen in pleural effusion samples.
authors.affiliation: Servei de Pneumologia, Hospital de Sant Boi, Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Andreo
authors.forename: J
authors.initials: J
authors.lastname: Domínguez
authors.forename: J
authors.initials: J
authors.lastname: Ruiz-Manzano
authors.forename: C
authors.initials: C
authors.lastname: Prat
authors.forename: S
authors.initials: S
authors.lastname: Blanco
authors.forename: L
authors.initials: L
authors.lastname: Lores
authors.forename: M D
authors.initials: MD
authors.lastname: Sánchez
authors.forename: I
authors.initials: I
authors.lastname: Latorre
authors.forename: M
authors.initials: M
authors.lastname: Giménez
authors.forename: V
authors.initials: V
authors.lastname: Ausina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000942:Antigens, Bacterial / Q000032:analysis* / Q000652:urine; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000276:immunology* / Q000382:microbiology; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis / Q000382:microbiology*; D012680:Sensitivity and Specificity; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D000942:Antigens, Bacterial