Association between blood pressure and survival over 9 years in a general population aged 85 and older.
OBJECTIVE
To investigate the association between blood pressure and mortality in people aged 85 and older.


METHODS
Population-based prospective study with 9-year follow-up.


METHODS
Department of Neuroscience and Neurology and Department of Public Health and General Practice, University of Kuopio, and Department of Clinical Neurosciences, Helsinki University Hospital.


METHODS
Of all 601 people living in the city of Vantaa born before April 1, 1906, whether living at home or in institutions and alive on April 1, 1991, 521 were clinically examined and underwent blood pressure measurement.


METHODS
Blood pressure was measured using a standardized method in the right arm of the subject after resting for at least 5 minutes. Information on medical history for each participant was verified from a computerized database containing all primary care health records. Death certificates were obtained from the National Register; the collection of death certificates was complete.


RESULTS
After adjusting for age, sex, functional status, and coexisting diseases (earlier-diagnosed myocardial infarction, congestive heart failure, dementia, cancer, stroke, or hypertension), low systolic blood pressure (BP) was associated with risk of death.


CONCLUSIONS
Low systolic BP may be partially related to poor general health and poor vitality, but the very old may represent a select group of individuals, and the use of BP-lowering medications needs to be evaluated in this group.
Rastas
Sari
S
Department of Neurology, Lohja Hospital, Lohja, Finland.
Pirttilä
Tuula
T
Viramo
Petteri
P
Verkkoniemi
Auli
A
Halonen
Pirjo
P
Juva
Kati
K
Niinistö
Leena
L
Mattila
Kimmo
K
Länsimies
Esko
E
Sulkava
Raimo
R
D000203:Activities of Daily Living; D000367:Age Factors; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D011795:Surveys and Questionnaires; D015996:Survival Rate / Q000639:trends; D014505:Urban Population / Q000706:statistics & numerical data