Acute tonsillopharyngitis associated with atypical bacterial infection in children: natural history and impact of macrolide therapy.
This study evaluated the natural history of acute tonsillopharyngitis associated with atypical bacterial infections, showing that Mycoplasma pneumoniae and Chlamydia pneumoniae organisms are frequently found in children with acute tonsillopharyngitis. The study also demonstrated, for what we believe to be the first time, that, unless adequately treated, acute tonsillopharyngitis associated with infection with M. pneumoniae and C. pneumoniae may have a negative outcome with a high risk of recurrence of respiratory illness.
Esposito
Susanna
S
Institute of Pediatrics, University of Milan, Milano, Italy.
Bosis
Samantha
S
Begliatti
Enrica
E
Droghetti
Roberta
R
Tremolati
Elena
E
Tagliabue
Claudia
C
Bellasio
Marta
M
Blasi
Francesco
F
Principi
Nicola
N
D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial; D017963:Azithromycin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D023521:Chlamydophila Infections / Q000188:drug therapy*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009175:Mycoplasma Infections / Q000188:drug therapy*; D009177:Mycoplasma pneumoniae / Q000276:immunology*; D010608:Pharyngeal Diseases / Q000188:drug therapy* / Q000382:microbiology*; D010612:Pharyngitis / Q000188:drug therapy / Q000382:microbiology; D012008:Recurrence; D014069:Tonsillitis / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017963:Azithromycin