title: Serial sonographic evaluation of Achilles tendons in patients taking fluoroquinolone antibiotics.
abstract: We performed a prospective study to determine if subclinical tendinopathy occurs in asymptomatic adults treated with fluoroquinolone antibiotics. Thirty-eight adults were enrolled. Serial ultrasounds of the Achilles tendons were performed. A board certified musculoskeletal radiologist interpreted the images in a blinded fashion. No changes were identified. Subclinical tendinopathy does not appear to exist in asymptomatic adults treated with fluoroquinolone antibiotics.
authors.affiliation: Tripler Army Medical Center Honolulu, HI 96859, USA.
authors.forename: Jefferson R
authors.initials: JR
authors.lastname: Roberts
authors.forename: Jay A
authors.initials: JA
authors.lastname: Hudson
authors.forename: Kenneth K
authors.initials: KK
authors.lastname: Lindell
authors.forename: David R
authors.initials: DR
authors.lastname: Finger
mesh_terms: D000125:Achilles Tendon / Q000000981:diagnostic imaging* / Q000187:drug effects*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000494:pharmacology; D000077734:Gatifloxacin; D006254:Hawaii; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D052256:Tendinopathy / Q000139:chemically induced*; D014463:Ultrasonography
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077734:Gatifloxacin