Perinatal infections and cerebral palsy.
Infections of the mother, the intrauterine environment, the fetus, and the neonate can cause cerebral palsy through a variety of mechanisms. Each of these processes is reviewed. The recently proposed theory of cytokine-induced white matter brain injury and the systemic inflammatory response syndrome with multiple organ dysfunction syndrome is critically evaluated.
Hermansen
Marcus C
MC
Department of Pediatrics, Dartmouth Medical School, Lebanon, NH 03756-0001, USA. marcus.hermansen@snhmc.org
Hermansen
Mary Goetz
MG
D002547:Cerebral Palsy / Q000382:microbiology*; D005260:Female; D005315:Fetal Diseases / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D007239:Infections / Q000382:microbiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D012307:Risk Factors