title: C-reactive protein in degenerative aortic valve stenosis.
abstract: Degenerative aortic valve stenosis includes a range of disorder severity from mild leaflet thickening without valve obstruction, "aortic sclerosis", to severe calcified aortic stenosis. It is a slowly progressive active process of valve modification similar to atherosclerosis for cardiovascular risk factors, lipoprotein deposition, chronic inflammation, and calcification. Systemic signs of inflammation, as wall and serum C-reactive protein, similar to those found in atherosclerosis, are present in patients with degenerative aortic valve stenosis and may be expression of a common disease, useful in monitoring of stenosis progression.
authors.affiliation: Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario de Valladolid, C/Ramón y Cajal n 3, 47005, Valladolid, Spain. pedrolsanchez@secardiologia.es
authors.forename: Pedro L
authors.initials: PL
authors.lastname: Sanchez
authors.forename: AnnaMaria
authors.initials: A
authors.lastname: Mazzone
mesh_terms: D001024:Aortic Valve Stenosis / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D018450:Disease Progression; D006801:Humans
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein