title: Ipsilateral percutaneous transhepatic portal vein embolization with gelatin sponge particles and coils in preparation for extended right hepatectomy for hilar cholangiocarcinoma.
abstract: OBJECTIVE
  To evaluate the effectiveness and safety of ipsilateral percutaneous transhepatic portal vein embolization (PTPVE) with gelatin sponge particles and coils to induce lobar hypertrophy in patients with hilar cholangiocarcinoma in preparation for extended right hepatectomy.
  
  
  METHODS
  Between 1999 and 2004, PTPVE was performed in 22 patients with hilar cholangiocarcinoma (mean age, 67 years; range, 57-77 y; 16 men and six women). Percutaneous puncture of the right portal vein was performed under ultrasound guidance. A reverse-curve catheter was used for right portal vein embolization. Coils were used to occlude second-order branches. The future liver remnant volume was assessed by comparing computed tomographic scans before and 14-24 days after PTPVE.
  
  
  RESULTS
  PTPVE was technically successful in all cases. The average increase in ratio of future liver remnant volume to total liver volume was 8.6%. Liver function tests after PTPVE but before surgery showed no significant changes. Nineteen patients underwent hepatic resection without liver failure. In three patients, tumors could not be removed because of detection of extrahepatic disease. One patient who underwent successful hepatic resection had an abscess in the removed right lobe.
  
  
  CONCLUSIONS
  Ipsilateral PTPVE with gelatin sponge and coils appears to be effective and safe for extended right hepatectomy for hilar cholangiocarcinoma.
authors.affiliation: Department of Radiology, Sendai Kousei Hospital, and Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Tsuda
authors.forename: Noriko
authors.initials: N
authors.lastname: Kurihara
authors.forename: Haruo
authors.initials: H
authors.lastname: Saito
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yamaki
authors.forename: Hiromune
authors.initials: H
authors.lastname: Shimamura
authors.forename: Youichi
authors.initials: Y
authors.lastname: Narushima
authors.forename: Syuichi
authors.initials: S
authors.lastname: Ishiyama
authors.forename: Akihiro
authors.initials: A
authors.lastname: Sato
authors.forename: Shoki
authors.initials: S
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006498:Hepatectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011169:Portal Vein; D011677:Punctures; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional