Clinical assessment of a new real time 3D quantitative coronary angiography system: evaluation in stented vessel segments.
BACKGROUND
Foreshortening is a recognized problem that is present in angiography and results from views that are not perpendicular to coronary lesions. This limits visual coronary analysis as well as 2D quantitative coronary angiography systems (QCA). The CardiOp-B System is a 3D image acquisition and processing software system designed as an add-on to conventional X-ray angiography system. CardiOp-B's features include real time and off line analysis with comprehensive 3D reconstruction integrating all of the available information of two 2D vessel angiographies into one 3D image. It was the aim of the study to analyze the accuracy of this new 3D QCA system.


METHODS
3D QCA was performed in 50 patients (age 64 +/- 10.9; 84% male; LV-EF 63 +/- 16%) measuring 61 stents during high-pressure inflation (diameter: 2.25-4 mm; length: 8-32 mm). The obtained values (proximal and distal stent diameter, stent length) were correlated with the predefined size of the stents at the used inflation pressure.


RESULTS
The linear correlation for the proximal stent diameter was Stent(prox)= 0.03 + 0.93 x real stent size (r(2) = 0.85). The linear correlation for the distal stent diameter was Stent(distal)= -0.03 + 0.89 x real stent size (r(2) = 0.81). The linear correlation for the stent length was Stent(length)= -0.61 + 1.02 x real stent length (r(2) = 0.98).


CONCLUSIONS
The CardiOp-B System(R) is a new 3D QCA system with a high linear correlation between the real vessel size and the obtained vessel dimension. It provides real time or off line accurate and comprehensive diagnostic information to the interventional cardiologist without changing the basic coronary angiography procedure.
Gradaus
Rainer
R
Department of Cardiology and Angiology, University Hospital Münster, Germany. gradaus@uni-muenster.de
Mathies
Klara
K
Breithardt
Günter
G
Böcker
Dirk
D
D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012984:Software; D015607:Stents; D013997:Time Factors; D014654:Vascular Patency