title: Nasal extranodal NK/T-cell lymphoma presenting as a perforating palatal ulcer: a diagnostic challenge.
abstract: A 40-year-old man presented with chronic nasal stuffiness and bloodstained discharge of 3 years' duration, along with a non-healing palatal ulcer since 2 months. Examination revealed a perforation in the midline on the hard palate and a superficial ulcer on the soft palate. Histopathology and immunohistochemistry suggested a diagnosis of extranodal nasal/nasal-type T-cell lymphoma. The patient was started on multiagent chemotherapy in the form of cyclophosphamide, doxorubicin, vincristine and prednisolone but succumbed after two cycles. Only one case of nasal T cell lymphoma presenting as nasal septal perforation, oronasal fistula and a concomitant palatal ulcer has been described. We report this case of a perforating palatal ulcer as a rare presentation of nasal lymphoma.
authors.affiliation: Department of Dermatology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India.
authors.forename: Vidula
authors.initials: V
authors.lastname: Patel
authors.forename: Sunanda
authors.initials: S
authors.lastname: Mahajan
authors.forename: Vidya
authors.initials: V
authors.lastname: Kharkar
authors.forename: Uday
authors.initials: U
authors.lastname: Khopkar
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D009059:Mouth Diseases / Q000175:diagnosis / Q000473:pathology*; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000473:pathology; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D019226:Oral Ulcer / Q000473:pathology*