title: Ras superfamily and interacting proteins database.
abstract: For geneticists and other researchers alike it is often useful to know how many related proteins might perform similar functions. With this in mind, a survey was performed to determine what proportion of human and Drosophila genes code for Ras superfamily members and their positive or negative regulators. Results indicate that just < 2% of genes in both genomes predict such proteins. A database was compiled to provide easy access to this information. This database also includes information on approximately 360 putative Ras superfamily effector proteins and may be a useful tool for those interested in GTPase biology.
authors.affiliation: Massachusetts General Hospital, Center for Cancer Research, Charlestown, Massachusetts, USA.
authors.forename: Andre
authors.initials: A
authors.lastname: Bernards
mesh_terms: D000818:Animals; D030562:Databases, Protein; D006801:Humans; D020559:Monomeric GTP-Binding Proteins / Q000235:genetics; D020703:ras GTPase-Activating Proteins / Q000235:genetics*; D018631:ras Proteins / Q000235:genetics*
chemical_list: D020703:ras GTPase-Activating Proteins; D020559:Monomeric GTP-Binding Proteins; D018631:ras Proteins