title: Zone 1 retinopathy of prematurity in a transitional economy: a cautionary note.
abstract: OBJECTIVE
  To describe three low risk infants in whom severe retinopathy of prematurity developed.
  
  
  METHODS
  A prospective, observational case series.
  
  
  METHODS
  setting: National Hospital of Pediatrics, Hanoi, Vietnam. study population: Premature infants in the neonatal ward. observation procedure: Eye examinations.
  
  
  RESULTS
  Severe retinopathy of prematurity occurred in three infants. All had zone 1 disease and other unusually severe findings, such as neovascularization of the disk. These infants would not be at risk for the development of such severe retinopathy of prematurity in countries with a developed economy.
  
  
  CONCLUSIONS
  Unusual characteristics of retinopathy of prematurity may be occurring in countries with transitional economies. Screening programs should be implemented and should take into consideration the possibility that retinopathy of prematurity may occur in infants who fall outside the screening guidelines that are used in the developed world.
authors.affiliation: Department of Ophthalmology, Royal Children's Hospital, University of Melbourne, Australia. Smcarden@aol.com
authors.forename: Susan M
authors.initials: SM
authors.lastname: Carden
authors.forename: Luu Ngoc
authors.initials: LN
authors.lastname: Lan
authors.forename: Tess
authors.initials: T
authors.lastname: Huynh
mesh_terms: D003906:Developing Countries / Q000191:economics*; D004467:Economics; D005260:Female; D005865:Gestational Age; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008297:Male; D009898:Optic Disk / Q000098:blood supply; D011446:Prospective Studies; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000209:etiology; D012178:Retinopathy of Prematurity / Q000175:diagnosis / Q000209:etiology*; D014744:Vietnam