Needle electromyographic findings in 98 patients with myositis.
OBJECTIVE
Little is known about the distribution of electromyographic (EMG) abnormalities in myositis even though this is relevant in daily practice.


METHODS
A retrospective semiquantitative analysis of needle EMG findings was performed in a group of 98 patients with myositis. The frequency, type, and distribution of abnormalities were studied. The influence of the use of corticosteroids and the stage of the disease were evaluated.


RESULTS
In most patients, a myopathic pattern with spontaneous activity was found, although several clinically relevant exceptions were noted. Long-duration motor unit potentials were found in all three diagnostic groups and were not associated with disease duration. In the lower extremity a distal to proximal gradient was present, adding to the diagnostic confusion with neurogenic diseases, and spontaneous activity was absent in a relatively large group although none of the patients in the acute stage of the disease had a normal EMG. The use of corticosteroids reduced the number of abnormal findings in dermatomyositis and polymyositis, but not in inclusion body myositis.


CONCLUSIONS
A myopathic pattern with spontaneous activity was most frequently found, although several clinically relevant exceptions were noted. These results illustrate the spectrum of EMG findings in myositis, and may aid the clinician in the interpretation of the EMG in these patients.
Blijham
Paul J
PJ
Department of Clinical Neurophysiology, Institute of Neurology, Institute of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Hengstman
Gerald J D
GJ
Hama-Amin
Ako Dara
AD
van Engelen
Baziel G M
BG
Zwarts
Machiel J
MJ
D001132:Arm; D015331:Cohort Studies; D003882:Dermatomyositis / Q000503:physiopathology; D004576:Electromyography / Q000379:methods*; D006801:Humans; D007249:Inflammation; D007866:Leg; D018482:Muscle, Skeletal / Q000503:physiopathology; D009220:Myositis / Q000503:physiopathology*; D018979:Myositis, Inclusion Body / Q000503:physiopathology; D018579:Patient Selection; D017285:Polymyositis / Q000503:physiopathology; D012189:Retrospective Studies