Tweaking of memory T helper 2 cells by TSLP.
Thymic stromal lymphopoietin conditions dendritic cells to support homeostatic proliferation of central memory T cells. In this issue of Immunity, Wang et al. (2006) show that these dendritic cells are critical in maintaining T helper 2 central memory cells and impart them with expression of unique proallergic molecules.
Kapsenberg
Martien
M
Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands; Department of Dermatology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands. Electronic address: m.l.kapsenberg@amc.uva.nl.
D016207:Cytokines / Q000494:pharmacology*; D003713:Dendritic Cells / Q000187:drug effects* / Q000276:immunology; D006801:Humans; D007156:Immunologic Memory / Q000235:genetics; D008213:Lymphocyte Activation / Q000235:genetics; D018418:Th2 Cells / Q000276:immunology*; D000094632:Thymic Stromal Lymphopoietin
D016207:Cytokines; D000094632:Thymic Stromal Lymphopoietin