Angiotensin-converting enzyme DD genotype is preventive against circulatory failure in very-low-birthweight neonates.
We studied the association between genetic polymorphisms of the renin-angiotensin system and the risk for circulatory failure (CF) during the first three postnatal days in 104 very-low-birthweight preterm infants.


CONCLUSIONS
Infants with angiotensin-converting enzyme DD genotype were protected against CF (adjusted OR 0.41, 95% CI 0.19-0.89).
Nobilis
András
A
Second Department of Obstetrics and Gynaecology, Semmelweis University, Budapest, Hungary.
Szabó
Miklós
M
Kocsis
István
I
Sulyok
Endre
E
Tulassay
Tivadar
T
Vásárhelyi
Barna
B
D005260:Female; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic; D012769:Shock / Q000201:enzymology / Q000235:genetics*
D007703:Peptidyl-Dipeptidase A