title: Food and probiotic strains from the Saccharomyces cerevisiae species as a possible origin of human systemic infections.
abstract: We report four cases of blood cultures testing positive for yeast strains belonging to the species Saccharomyces cerevisiae. Using molecular techniques, RFLP of mtDNA and delta-PCR amplification, we show the association of two of the isolates with non-clinical strains. Specifically, with two commercial bread-making strains and the therapeutic S. boulardii strain. The association of S. boulardii with cases of fungemia has been reported previously. Nevertheless, this is the first time that a baker's yeast has been isolated from blood.
authors.affiliation: Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de los Alimentos (CSIC), 46100 Burjassot, Valencia, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: de Llanos
authors.forename: Amparo
authors.initials: A
authors.lastname: Querol
authors.forename: Javier
authors.initials: J
authors.lastname: Pemán
authors.forename: Miguel
authors.initials: M
authors.lastname: Gobernado
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Fernández-Espinar
mesh_terms: D000368:Aged; D002648:Child; D004271:DNA, Fungal / Q000032:analysis*; D004272:DNA, Mitochondrial / Q000032:analysis; D005260:Female; D005516:Food Microbiology; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D007223:Infant; D008297:Male; D016533:Mycological Typing Techniques; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length; D019936:Probiotics; D012441:Saccharomyces cerevisiae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial