title: A comparison of PCDD/PCDFs exposure in infants via formula milk or breast milk feeding.
abstract: Food is the major source for polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) accumulation in human body. In infant period, breast milk and formula milk are the major food sources. Congener-specific analyses of 17 PCDD/PCDFs were performed on 10 brands of formula milk samples which were milk-based and 37 breast milk samples collected from women living in southern Taiwan. The levels of 17 PCDD/PCDFs in 10 formula milk samples ranged from 0.468 to 0.962 pg WHO-TEQ/g lipid, with a mean value of 0.713+/-0.163 pg WHO-TEQ/g lipid. For the 37 breast milk samples, their PCDD/PCDF levels were 14.7+/-9.36 pg WHO-TEQ/g lipid, with a range between 4.21 and 52.8 pg WHO-TEQ/g lipid. At 12th month of age for infants, average daily intakes (ADI) of PCDD/PCDFs were 2.1 pg WHO-TEQ/kg/day for the formula-feeding infants, and 13 pg WHO-TEQ/kg/day for the breast-feeding infants. The present data may provide useful information for risk-benefit evaluation of formula- and breast-feeding.
authors.affiliation: Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 70428, Taiwan.
authors.forename: Jing-Fang
authors.initials: JF
authors.lastname: Hsu
authors.forename: Yueliang Leon
authors.initials: YL
authors.lastname: Guo
authors.forename: Chun-Hu
authors.initials: CH
authors.lastname: Liu
authors.forename: Shu-Chuan
authors.initials: SC
authors.lastname: Hu
authors.forename: Jieh-Neng
authors.initials: JN
authors.lastname: Wang
authors.forename: Pao-Chi
authors.initials: PC
authors.lastname: Liao
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000032:analysis*; D001942:Breast Feeding; D000072338:Dibenzofurans, Polychlorinated; D005260:Female; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000737:chemistry*; D007231:Infant, Newborn; D008895:Milk, Human / Q000737:chemistry*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis; D013624:Taiwan
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins