Eplerenone inhibits tumour necrosis factor alpha shedding process by tumour necrosis factor alpha converting enzyme in monocytes from patients with congestive heart failure.
Satoh
M
M
Ishikawa
Y
Y
Minami
Y
Y
Akatsu
T
T
Nakamura
M
M
D051722:ADAM Proteins / Q000037:antagonists & inhibitors; D000072198:ADAM17 Protein; D004305:Dose-Response Relationship, Drug; D000077545:Eplerenone; D006333:Heart Failure / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D009000:Monocytes / Q000378:metabolism*; D013148:Spironolactone / Q000031:analogs & derivatives* / Q000494:pharmacology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D014409:Tumor Necrosis Factor-alpha; D013148:Spironolactone; D000077545:Eplerenone; D051722:ADAM Proteins; D000072198:ADAM17 Protein