[Cytoarchitecture of lymphoid tissue in tracheal mucosa as affected by diamond dust].
The effect of diamond dust on lymphoid aggregates in tracheal mucosa after the exposure for various time periods was studied in mature Wistar rats, which were placed under the natural conditions of diamond-processing factory. Exposure to diamond dust resulted in the changes of cell content of lymphoid aggregates in tracheal mucosa already at the early stages of an experiment (Day 3). The proportion of small lymphocytes was decreased, while the content of medium lymphocytes and undifferentiated cells was increased simultaneously with the augmentation of the number of macrophages and cells undergoing destruction. At Day 30 in subepithelial area and in the basal region of lymphoid nodules, the reduction of the number of small lymphocytes was also accompanied by the significant increase of macrophages and cells undergoing destruction.
Garmaeva
D K
DK
D000818:Animals; D018130:Diamond / Q000633:toxicity*; D004391:Dust; D008214:Lymphocytes / Q000166:cytology; D008221:Lymphoid Tissue / Q000166:cytology*; D008264:Macrophages / Q000166:cytology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D020545:Respiratory Mucosa / Q000166:cytology / Q000276:immunology*; D014132:Trachea / Q000166:cytology / Q000276:immunology*
D004391:Dust; D018130:Diamond