Coexistent Marfan's syndrome and ankylosing spondylitis.
We describe a 22-year-old woman with coexisting Marfan's syndrome (MFS) and ankylosing spondylitis (AS). A change of fibrillin-1 due to mutation of the FBN1 gene (MFS) or a cell-mediated autoimmune response in AS could account for a common pathology.
Kiss
Csaba
C
National Institute of Rheumatology and Physiotherapy, 1st Department of Rheumatology, Budapest, Hungary. kiss.csaba@mail.orfi.hu
Jónap
Ildiko
I
Gergely
Peter
P
Poór
Gyula
G
D000328:Adult; D004452:Echocardiography; D005260:Female; D000071838:Fibrillin-1; D000071837:Fibrillins; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000175:diagnosis; D054392:Adipokines
D000071838:Fibrillin-1; D000071837:Fibrillins; D008840:Microfilament Proteins; C000605722:FBN1 protein, human; D054392:Adipokines