[Detection and significance of 16S rDNA in the prostatic secretions of patients with chronic prostatitis].
OBJECTIVE
To evaluate the expression and significance of 16S rDNA in prostatic secretions (EPS) of chronic prostatitis.


METHODS
16S rDNA was detected in EPS of 116 patients with chronic prostatitis by PCR.


RESULTS
16S rDNA were positively expressed in all 29 cases of II type chronic bacterial prostatitis and 71 out of 87 cases of III type chronic prostatitis (82%). The positive rates were 94% (45/48) and 67% (26/39) in lIIA and IIIB chronic prostatitis respectively. There was a statistical difference in 16S rDNA positive rate between IIIA and IlB chronic prostatitis (P < 0.01).


CONCLUSIONS
Detection of 16s rDNA may be a useful index for the diagnosis and classification of chronic prostatitis.
Liu
Shi-Jun
SJ
Department of Urology, People's Hospital of Peking University, Beijing 100044, China. liushijun1206@sina.com
Chen
Guo-Qiang
GQ
Ye
Hai-Yun
HY
Wang
Xiao-Feng
XF
D000328:Adult; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis*; D012634:Bodily Secretions / Q000737:chemistry; D002908:Chronic Disease; D004275:DNA, Ribosomal / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D011467:Prostate / Q000378:metabolism; D011472:Prostatitis / Q000145:classification / Q000175:diagnosis* / Q000382:microbiology
D004275:DNA, Ribosomal