title: Phylogenetic analysis of previously nontypeable hepatitis C virus isolates from Argentina.
abstract: Phylogenetic analysis of hepatitis C virus isolates from Argentina that were previously nontypeable by restriction fragment length polymorphism (RFLP) analysis revealed that they belong to genotype 1a. A substitution at position 107 (G-->A), which is the landmark of these strains, was shown to be distributed among isolates worldwide. The RFLP patterns obtained for these isolates should be added to the ones reported for genotype 1 isolates.
authors.affiliation: Laboratorio de Virología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD Ciudad de Buenos Aires, Argentina. migismondi@yahoo.com.ar
authors.forename: María Inés
authors.initials: MI
authors.lastname: Gismondi
authors.forename: Pablo Daniel
authors.initials: PD
authors.lastname: Becker
authors.forename: Pamela
authors.initials: P
authors.lastname: Valva
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Guzmán
authors.forename: María Victoria
authors.initials: MV
authors.lastname: Preciado
mesh_terms: D020121:5' Untranslated Regions / Q000235:genetics; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D019698:Hepatitis C, Chronic / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007231:Infant, Newborn; D008969:Molecular Sequence Data; D010802:Phylogeny; D012150:Polymorphism, Restriction Fragment Length; D017422:Sequence Analysis, DNA
chemical_list: D020121:5' Untranslated Regions