[Metabolic PPAR nuclear receptors and skin].
Activators of metabolic PPAR receptors are used in diabetology and lipidology. Many substance influancing PPAR (beta/delta) are in research. These substances will be perhaps used in obesitology and in atherosclerosis treatment. Much quicker is approaching the use in dermatology. The effect of receptor stimulation will be used in wound healing and in the treatment of allergic and proliferative diseases. Some realeted substancies influencing heterodimers with RXR or RAR receptors are used in the treatment of acne and skin lymfomas. Dermatology will be after internal medicine the second field where influencing of PPAR receptors will be very important.
Svacina
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III interní klinika 1. 1ékarské fakulty UK a VFN, Praha. svacinas@lf1.cuni.cz
D006801:Humans; D047492:Peroxisome Proliferator-Activated Receptors / Q000187:drug effects / Q000502:physiology*; D012867:Skin / Q000166:cytology / Q000378:metabolism; D012871:Skin Diseases / Q000503:physiopathology; D014945:Wound Healing / Q000502:physiology
D047492:Peroxisome Proliferator-Activated Receptors