Serial sonographic evaluation of Achilles tendons in patients taking fluoroquinolone antibiotics.
We performed a prospective study to determine if subclinical tendinopathy occurs in asymptomatic adults treated with fluoroquinolone antibiotics. Thirty-eight adults were enrolled. Serial ultrasounds of the Achilles tendons were performed. A board certified musculoskeletal radiologist interpreted the images in a blinded fashion. No changes were identified. Subclinical tendinopathy does not appear to exist in asymptomatic adults treated with fluoroquinolone antibiotics.
Roberts
Jefferson R
JR
Tripler Army Medical Center Honolulu, HI 96859, USA.
Hudson
Jay A
JA
Lindell
Kenneth K
KK
Finger
David R
DR
D000125:Achilles Tendon / Q000000981:diagnostic imaging* / Q000187:drug effects*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000494:pharmacology; D000077734:Gatifloxacin; D006254:Hawaii; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D052256:Tendinopathy / Q000139:chemically induced*; D014463:Ultrasonography
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077734:Gatifloxacin