Pericardial mesothelioma in a neonatal calf.
We encountered an extremely rare tumor, a pericardial mesothelioma, in a neonatal calf. The patient calf showed severe abdominal distention, and died immediately after birth. The thoracic cavity was contained a huge heart with a large amount of pericardial fluid. A number of granular and cobblestone-like nodules were dispersed over the epicardium and pericardium. The nodules consisted of papillary proliferations of neoplastic cells, and the neoplasm occasionally showed mesenchymal proliferations. Immunohistochemistry revealed that they had the characteristics of mesothelial cells (cytokeratin-and vimentin-positive), and the neoplasm was diagnosed as mesothelioma.
Takasu
Masaki
M
Department of Clinical Veterinary Medicine, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
Shirota
Kinji
K
Uchida
Naohiro
N
Iguchi
Tomonori
T
Nishii
Naohito
N
Ohba
Yasunori
Y
Maeda
Sadatoshi
S
Miyazawa
Kiyoshi
K
Murase
Tetsuma
T
Kitagawa
Hitoshi
H
D000818:Animals; D000831:Animals, Newborn; D001202:Ascitic Fluid; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000473:pathology*; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008654:Mesothelioma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D010490:Pericardial Effusion / Q000209:etiology; D010496:Pericardium / Q000473:pathology*