Three-component synthesis of dialkyl 2-(alkylimino-methylene)3- (2,2,5-trimethyl-4,6-dioxo-1,3-dioxan-5-yl)-succinates.
The adduct produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates was trapped by 2,2,5-trimethyl-1,3-dioxane-4,6-dione (methyl Meldrum's acid), to afford highly functionalized ketenimines in good yields.
Yavari
Issa
I
Department of Chemistry, Science & Research Campus, Islamic Azad University, Ponak, Tehran, Iran. yavarisa@modares.ac.ir
Zare
Hasan
H
Mohtat
Bita
B
D000480:Alkynes; D020650:Combinatorial Chemistry Techniques; D003486:Cyanides / Q000737:chemistry*; D004146:Dioxanes / Q000737:chemistry*; D005231:Fatty Acids, Unsaturated / Q000737:chemistry*; D013386:Succinates / Q000138:chemical synthesis*
D000480:Alkynes; D003486:Cyanides; D004146:Dioxanes; D005231:Fatty Acids, Unsaturated; D013386:Succinates; C024060:2-butynedioic acid; C076489:Meldrum's acid