[Some pathogenic mechanisms of aerozol-therapy including cyclopheron treatment in patients with chronic rhinitis].
High prevalence of chronic rhinitis makes more topical the problem of search of new, more effective means of treatment of these pathologies with the establishment of pathogenic mechanisms of the action of these means. Total of 62 patients were investigated. 34 of these patients had chronic catarrhal rhinitis and 28 - chronic allergic rhinitis. It has been established that the use of cyclopheron in aerosol-therapy increases the cortisol discharge from the blood of the patients with rhinitis. It decreases up to the disappearance the inflammatory process in nasal mucus, which strengthens cellular immunity, has a desensitization action, increases non-specific resistance of the organism and has a normalizing action on the indices of humoral immunity. The above shown positive shifts were more pronounced in chronic catarrhal rhinitis.
Tarkhan-Mouravi
I D
ID
Lomaia
M M
MM
D000166:Acridines / Q000008:administration & dosage / Q000627:therapeutic use*; D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007369:Interferon Inducers / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012220:Rhinitis / Q000188:drug therapy* / Q000276:immunology; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000276:immunology; D016896:Treatment Outcome
D000166:Acridines; D007369:Interferon Inducers; D006854:Hydrocortisone; C026430:10-carboxymethyl-9-acridanone