[Clinical significance of early diagnose and treatment of subclinical renal allograft rejection].
OBJECTIVE
To explore the clinical significance of early diagnose and treatment of subclinical renal allograft rejection.


METHODS
Ninety-six renal allograft recipients (54 male and 42 female) with normal renal function aged 17 to 58 years (mean 37.5 years) were included in this study. Early subclinical rejection was diagnosed 3 months after the transplantation by color Doppler examination.


RESULTS
Patients with early subclinical rejection were given methylpredisolone followed by adjustment of immunosuppressive regimens, and no difference was observed in 3-year survival rate between these patients and those with normal renal allograft findings.


CONCLUSIONS
Early diagnosis and treatment of subclinical renal allograft rejection is significant to improve renal allograft survival rate.
Zeng
Jing-hua
JH
Department of Urology, 421 Hospital of the Navy, Guangzhou 510318, China. zjh421421@126.com
Yu
Li-xin
LX
Luo
Han-hong
HH
Wang
Xiao-chun
XC
Wang
Xin
X
Fang
Wei
W
D000293:Adolescent; D000328:Adult; D000368:Aged; D042241:Early Diagnosis; D005260:Female; D006084:Graft Rejection / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D006085:Graft Survival / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color
D007166:Immunosuppressive Agents; D008775:Methylprednisolone