title: Indirect flow rate estimation of the NEDO PI Gyro pump for chronic BVAD experiments.
abstract: In totally implantable ventricular assist device systems, measuring flow rate of the pump is necessary to ensure proper operation of the pump in response to the recipient's condition or pump malfunction. To avoid problems associated with the use of flow probes, several methods for estimating flow rate of a rotary blood pump used as a ventricular assist device have been studied. In the present study, we have performed a chronic animal experiment with two NEDO PI gyro pumps as the biventricular assist device for 63 days to evaluate our estimation method by comparing the estimated flow rate with the measured one every 2 days. Up to 15 days after identification of the parameters, our estimations were accurate. Errors increased during postoperation days 20 to 30. Meanwhile, their correlation coefficient r was higher than 0.9 in all the acquired data, and estimated flow rate could simulate the profile of the measured one.
authors.affiliation: Graduate School of Engineering, Tohoku University, Sendai, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ogawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshizawa
authors.forename: Akira
authors.initials: A
authors.lastname: Tanaka
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Abe
authors.forename: Paul
authors.initials: P
authors.lastname: Olegario
authors.forename: Tadashi
authors.initials: T
authors.lastname: Motomura
authors.forename: Hisashi
authors.initials: H
authors.lastname: Okubo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Oda
authors.forename: Toshiya
authors.initials: T
authors.lastname: Okahisa
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Igo
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Nosé
mesh_terms: D000818:Animals; D002417:Cattle; D002498:Centrifugation; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006354:Heart, Artificial; D006353:Heart-Assist Devices; D020007:Implants, Experimental; D007260:Infusion Pumps; D008904:Miniaturization; D023421:Models, Animal; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D012107:Research Design