title: Acoustic speed and attenuation coefficient in sheep aorta measured at 5-9 MHz.
abstract: B-mode ultrasound (US) images from blood vessels in vivo differ significantly from vascular flow phantom images. Phantoms with acoustic properties more closely matched to those of in vivo arteries may give better images. A method was developed for measuring the speed and attenuation coefficient of US over the range 5 to 9 MHz in samples of sheep aorta using a pulse-echo technique. The times-of-flight method was used with envelope functions to identify the reference points. The method was tested with samples of tissue-mimicking material of known acoustic properties. The tissue samples were stored in Krebs physiologic buffer solution and measured over a range of temperatures. At 37 degrees C, the acoustic speed and attenuation coefficient as a function of frequency in MHz were 1600 +/- 50 ms(-1) and 1.5 +/- 4f(0.94 +/- 1.3) dB cm(-1), respectively.
authors.affiliation: Medical Physics, The University of Edinburgh, Edinburgh, Scotland. kate.fraser@ed.ac.uk
authors.forename: Katharine H
authors.initials: KH
authors.lastname: Fraser
authors.forename: Tamie L
authors.initials: TL
authors.lastname: Poepping
authors.forename: Alan
authors.initials: A
authors.lastname: McNeilly
authors.forename: Ian L
authors.initials: IL
authors.lastname: Megson
authors.forename: Peter R
authors.initials: PR
authors.lastname: Hoskins
mesh_terms: D000162:Acoustics; D000818:Animals; D001011:Aorta / Q000000981:diagnostic imaging* / Q000502:physiology; D001831:Body Temperature; D007552:Isotonic Solutions; D033401:Microscopy, Acoustic; D019047:Phantoms, Imaging; D012756:Sheep; D013696:Temperature; D014021:Tissue Preservation / Q000379:methods
chemical_list: D007552:Isotonic Solutions; C051865:Krebs-Ringer solution