title: Downstream effects of esophageal distention.
abstract: This review focuses on primary peristalsis and the normal swallow and secondary peristalsis as it relates to esophageal distention. In addition, high-pressure zones in the esophageal sphincters and innervation in the esophageal body are discussed. Distention-induced protective reflexes for the pharynx and airway are described, as are extraesophageal effects of esophageal distention. Experimental and clinical research in these areas is summarized, along with its possible clinical applications.
authors.affiliation: Temple University School of Medicine, 3401 North Broad Street, Philadelphia, PA 19140, USA.
authors.forename: Harvey
authors.initials: H
authors.lastname: Licht
authors.forename: Robert S
authors.initials: RS
authors.lastname: Fisher
mesh_terms: D003679:Deglutition / Q000502:physiology*; D004106:Dilatation; D004947:Esophagus / Q000502:physiology*; D006801:Humans; D010528:Peristalsis; D010614:Pharynx / Q000502:physiology; D012018:Reflex / Q000502:physiology