title: Pregnancy complicated with Buerger's disease.
abstract: Buerger's disease is an inflammatory occlusive vascular disorder involving small- and medium-sized arteries in the distal extremities and is usually complicated with thrombophlebitis. Since Buerger's disease develops most frequently in men who smoke, pregnancy complicated with this disease is extremely rare. Only three pregnancies have been reported previously. All cases indicate that Buerger's disease worsens during pregnancy. However, anti-coagulant therapy appeared to be effective in this case. Accordingly, careful observation is mandatory in pregnancies complicated with Buerger's disease.
authors.affiliation: Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan. kk-nori@hsp.md.shinshu-u.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Kikuchi
authors.forename: M
authors.initials: M
authors.lastname: Kanai
authors.forename: N
authors.initials: N
authors.lastname: Kita
authors.forename: Y
authors.initials: Y
authors.lastname: Mitsuhashi
authors.forename: I
authors.initials: I
authors.lastname: Konishi
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D013919:Thromboangiitis Obliterans / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D014470:Umbilical Cord / Q000473:pathology
chemical_list: D000925:Anticoagulants; D006493:Heparin