title: Pregnancy and C1 esterase inhibitor deficiency: a successful outcome.
abstract: Hereditary angioedema is a potentially life-threatening condition which can complicate pregnancy. A 34-year-old patient with known C1 esterase inhibitor (C1INH) deficiency was managed successfully in our department and her management was a part of a shared care strategy with the medical and anesthetic departments. Peripartum management plans along with an anesthetic plan were drawn up and clearly displayed in her records. She was admitted three times with abdominal pain which were self-limiting before she was admitted at term. An aggressive management strategy with C1INH concentrate facilitated a normal vaginal delivery.
authors.affiliation: Department of Obstetrics and Gynaecology, New Cross Hospital, Wolverhampton, 10 0QP, UK. lungdoc@doctors.org.uk
authors.forename: Fatima
authors.initials: F
authors.lastname: Nathani
authors.forename: Helen
authors.initials: H
authors.lastname: Sullivan
authors.forename: David
authors.initials: D
authors.lastname: Churchill
mesh_terms: D000328:Adult; D000799:Angioedema / Q000209:etiology / Q000628:therapy*; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D010347:Patient Care Planning; D010348:Patient Care Team; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*
chemical_list: D003174:Complement C1 Inactivator Proteins