title: [Clinical significance of early diagnose and treatment of subclinical renal allograft rejection].
abstract: OBJECTIVE
  To explore the clinical significance of early diagnose and treatment of subclinical renal allograft rejection.
  
  
  METHODS
  Ninety-six renal allograft recipients (54 male and 42 female) with normal renal function aged 17 to 58 years (mean 37.5 years) were included in this study. Early subclinical rejection was diagnosed 3 months after the transplantation by color Doppler examination.
  
  
  RESULTS
  Patients with early subclinical rejection were given methylpredisolone followed by adjustment of immunosuppressive regimens, and no difference was observed in 3-year survival rate between these patients and those with normal renal allograft findings.
  
  
  CONCLUSIONS
  Early diagnosis and treatment of subclinical renal allograft rejection is significant to improve renal allograft survival rate.
authors.affiliation: Department of Urology, 421 Hospital of the Navy, Guangzhou 510318, China. zjh421421@126.com
authors.forename: Jing-hua
authors.initials: JH
authors.lastname: Zeng
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Yu
authors.forename: Han-hong
authors.initials: HH
authors.lastname: Luo
authors.forename: Xiao-chun
authors.initials: XC
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Fang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D042241:Early Diagnosis; D005260:Female; D006084:Graft Rejection / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D006085:Graft Survival / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color
chemical_list: D007166:Immunosuppressive Agents; D008775:Methylprednisolone