West Nile and St. Louis encephalitis virus antibody seroconversion, prevalence, and persistence in naturally infected pig-tailed macaques (Macaca nemestrina).
Pig-tailed macaques (Macaca nemestrina) naturally infected with West Nile virus were monitored from 1999 to 2005 to determine virus-specific antibody seroconversion, prevalence, and persistence. Antibodies persisted for up to 36 months, as detected by epitope-blocking enzyme-linked immunosorbent and hemagglutination inhibition assays. Exposure to cocirculating St. Louis encephalitis virus was evaluated by Western blotting and immunofluorescence assays.
Hukkanen
Renee R
RR
Deparatment of Comparative Medicine, Box 357190, University of Wasington School of Medicine, Seattle, 98195-7330, USA. rgamboa@u.washington.edu
Liggitt
H Denny
HD
Kelley
Stephen T
ST
Grant
Richard
R
Anderson
David M
DM
Hall
Roy A
RA
Tesh
Robert B
RB
Travassos DaRosa
Amelia P
AP
Bielefeldt-Ohmann
Helle
H
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D015153:Blotting, Western / Q000379:methods; D004665:Encephalitis Virus, St. Louis / Q000276:immunology*; D004674:Encephalitis, St. Louis / Q000097:blood* / Q000276:immunology / Q000662:veterinary / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005500:Follow-Up Studies; D006679:HIV Seropositivity; D006385:Hemagglutination Inhibition Tests / Q000379:methods; D008254:Macaca nemestrina / Q000821:virology*; D015995:Prevalence; D012189:Retrospective Studies; D014901:West Nile Fever / Q000097:blood* / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary; D014902:West Nile virus / Q000276:immunology*
D000914:Antibodies, Viral