title: Autologous mononuclear bone marrow cells during reparative regeneratrion after acute myocardial infarction.
abstract: A randomized controlled study included 44 patients with acute myocardial infarction. It was found that intracoronary injection of bone marrow mononuclear cells is safe, ensures fixation of the injected cells in the myocardium, reduces blood levels of IL-1beta and TNF-alpha, increases the content insulin-like growth factor, and does not provoke malignant arrhythmias.
authors.affiliation: Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
authors.forename: R S
authors.initials: RS
authors.lastname: Karpov
authors.forename: S V
authors.initials: SV
authors.lastname: Popov
authors.forename: V A
authors.initials: VA
authors.lastname: Markov
authors.forename: T E
authors.initials: TE
authors.lastname: Suslova
authors.forename: V V
authors.initials: VV
authors.lastname: Ryabov
authors.forename: Yu S
authors.initials: YS
authors.lastname: Poponina
authors.forename: A L
authors.initials: AL
authors.lastname: Krylov
authors.forename: S V
authors.initials: SV
authors.lastname: Sazonova
mesh_terms: D000328:Adult; D000368:Aged; D001854:Bone Marrow Cells / Q000166:cytology*; D050556:Fatty Acid-Binding Proteins / Q000097:blood; D005260:Female; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000096:biosynthesis; D007375:Interleukin-1 / Q000097:blood; D007963:Leukocytes, Mononuclear / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000378:metabolism; D012038:Regeneration; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
chemical_list: D050556:Fatty Acid-Binding Proteins; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha; D007334:Insulin-Like Growth Factor I