title: [Clinical study of periocline on peri-implantitis treatment].
abstract: OBJECTIVE
  To evaluate the clinical outcome and the effects of treating peri-implantitis with periocline.
  
  
  METHODS
  Thirty-two sites in 32 implants with peri-implantitis were treated with periocline. The parameters including plaque index, probing depth (PD) of pocket, sulcular bleeding index (SBI) were measured at baseline, 1, 3, 6 and 12 weeks after treatment and followed up for 6 months.
  
  
  RESULTS
  Statistically significant decrease (P < 0.05) in SBI, and PD occurred at all time intervals compared to baseline. The treatment could last for at lest four weeks in peri-implantitis cases without fistula.
  
  
  CONCLUSIONS
  Periocline could be safely and effectively used in treating peri-implantitis in cases without peri-implant fistula. Peri-implantitis with fistula should be treated in combination with surgical methods, and periocline can also be used to control inflammation before surgery.
authors.affiliation: LIU Hong Dental Clinic, Beijing 100088, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhou
authors.forename: Ye
authors.initials: Y
authors.lastname: Lin
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Qiu
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Xiu-lian
authors.initials: XL
authors.lastname: Hu
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use*; D010518:Periodontitis / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D015921:Dental Implants; D008911:Minocycline