Hypoglycaemic activity of two spices extracts: Rhus coriaria L. and Bunium persicum Boiss.
The hypoglycaemic efficacy of sumac (Rhus coriaria L.) and black cumin (Bunium persicum Boiss) extracts were investigated through inhibition of a glycoside hydrolase: alpha-amylase. On the basis of our result ethyl acetate extract of sumac may have interest in the treatment and prevention of hyperglycaemia, diabetes and obesity, with an IC50 value of 28.7 microg mL-1.
Giancarlo
Statti
S
Department of Pharmaceutical Sciences, University of Calabria, I-87036 Rende (CS), Italy.
Rosa
Loizzo Monica
LM
Nadjafi
Farsad
F
Francesco
Menichini
M
D019661:Apiaceae / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D029045:Rhus / Q000737:chemistry*; D000516:alpha-Amylases / Q000037:antagonists & inhibitors / Q000378:metabolism
D005419:Flavonoids; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000516:alpha-Amylases