title: Unnoticed spread of class 1 integrons in gram-positive clinical strains isolated in Guangzhou, China.
abstract: A total of 46 gram-positive bacteria isolated from clinical specimens collected in China were subjected to PCR analysis with the intI1-specific primers, and the intI1-positive strains were further analyzed for their resistance gene cassette. All isolates possessed the class 1 integron in their genomes and the array of gene cassettes was dhfrXII-orfF-aadA2, which is very similar to other organisms except in one isolate carrying an additional copy of the class 1 integron containing the aadA2 gene cassette. Altogether, the results indicate that the class 1 integron is widespread in gram-positive clinical strains isolated in Guangzhou, China.
authors.affiliation: College of Food and Biological Engineering, South China University of Technology.
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Meiping
authors.initials: M
authors.lastname: Zheng
authors.forename: Zenghuang
authors.initials: Z
authors.lastname: Xiao
authors.forename: Masahiro
authors.initials: M
authors.lastname: Asakura
authors.forename: Jianyu
authors.initials: J
authors.lastname: Su
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.forename: Shinji
authors.initials: S
authors.lastname: Yamasaki
mesh_terms: D024881:Drug Resistance, Bacterial / Q000235:genetics; D022761:Gene Transfer, Horizontal; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D032023:Integrons; D008826:Microbial Sensitivity Tests