Magnetoencephalography (MEG) determined temporal modulation of visual and auditory sensory processing in the context of classical conditioning to faces.
Using magnetoencephalography (MEG), we determined the time course of sensory-evoked modulations during differential aversive conditioning to faces, with an aversive noise event (UCS). Conditioning was associated with the development of a differential event-related waveform peaking at approximately 150 ms. Source analysis indicated the localization of this modulation to ventral occipital regions. In the auditory domain, a modulation of auditory-evoked responses to a probe sound was evident in a late component emerging at approximately 180 ms over sensors in fronto-temporal regions. The findings indicate the time course in processing sensory stimuli can be altered on the basis of their acquired value.
Dolan
R J
RJ
Institute of Neurology, University College London, UK. r.dolan@fil.ion.ucl.ac.uk
Heinze
H J
HJ
Hurlemann
R
R
Hinrichs
H
H
D000328:Adult; D000679:Amygdala / Q000502:physiology; D000786:Anger / Q000502:physiology; D001245:Association Learning / Q000502:physiology; D001288:Attention / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D003214:Conditioning, Classical / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D004644:Emotions / Q000502:physiology*; D005149:Facial Expression; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D009622:Noise; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted