title: New eremophilane-type sesquiterpenes from Ligularia hodgsonii.
abstract: Four new eremophilanlides (1- 4) together with a known sesquiterpene were isolated from the roots and rhizomes of Ligularia hodgsonii. The structures of these new compounds were established as 6beta-(2'-methylbutanoyloxy)-10beta-acetoxy-3 beta, 8beta-dihydroxyeremophil-7(11)-en-8,12-olide (1), 6beta,10 beta-dihydroxyeremophil-7(11)-en-8alpha,12-olide (2), 3beta-acetoxy-6,9-dien-8-oxoeremophil-12-nor-11-ketone (3), and 3beta-acetoxy-6alpha, 8alpha-dihydroxyeremophil-7(11), 9-dien-8,12-olide (4) by means of mass, IR and NMR spectroscopy.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai, P. R. China.
authors.forename: Ji-Qing
authors.initials: JQ
authors.lastname: Xu
authors.forename: Yun-Sen
authors.initials: YS
authors.lastname: Li
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Li
authors.forename: Shan-Hao
authors.initials: SH
authors.lastname: Jiang
authors.forename: Chang-Heng
authors.initials: CH
authors.lastname: Tan
authors.forename: Da-Yuan
authors.initials: DY
authors.lastname: Zhu
mesh_terms: D019659:Asteraceae; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009281:Naphthalenes / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots; D000081223:Polycyclic Sesquiterpenes; D027343:Rhizome; D012717:Sesquiterpenes / Q000737:chemistry; D013055:Spectrophotometry, Infrared
chemical_list: D009281:Naphthalenes; D010936:Plant Extracts; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds