title: Pericardial mesothelioma in a neonatal calf.
abstract: We encountered an extremely rare tumor, a pericardial mesothelioma, in a neonatal calf. The patient calf showed severe abdominal distention, and died immediately after birth. The thoracic cavity was contained a huge heart with a large amount of pericardial fluid. A number of granular and cobblestone-like nodules were dispersed over the epicardium and pericardium. The nodules consisted of papillary proliferations of neoplastic cells, and the neoplasm occasionally showed mesenchymal proliferations. Immunohistochemistry revealed that they had the characteristics of mesothelial cells (cytokeratin-and vimentin-positive), and the neoplasm was diagnosed as mesothelioma.
authors.affiliation: Department of Clinical Veterinary Medicine, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Takasu
authors.forename: Kinji
authors.initials: K
authors.lastname: Shirota
authors.forename: Naohiro
authors.initials: N
authors.lastname: Uchida
authors.forename: Tomonori
authors.initials: T
authors.lastname: Iguchi
authors.forename: Naohito
authors.initials: N
authors.lastname: Nishii
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ohba
authors.forename: Sadatoshi
authors.initials: S
authors.lastname: Maeda
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Miyazawa
authors.forename: Tetsuma
authors.initials: T
authors.lastname: Murase
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kitagawa
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001202:Ascitic Fluid; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000473:pathology*; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008654:Mesothelioma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D010490:Pericardial Effusion / Q000209:etiology; D010496:Pericardium / Q000473:pathology*