title: [Perioperative management of severe obstructive sleep apnea hypopnea syndrome].
abstract: OBJECTIVE
  To investigate the perioperative management of severe obstructive sleep apnea hypopnea syndrome (OSAHS).
  
  
  METHODS
  Fifty-three patients with severe OSAHS received uvulopalatopharyngoplasty with uvula preservation and radiofrequency tongue base reduction. All the patients were treated with automated continuous positive airway pressure (CPAP) for 3-7 days before operation and automated antibiotic therapy administered in the oropharynx, with 24 h ECG monitoring postoperatively. Polysomnography were carried out before and 6 months after surgery.
  
  
  RESULTS
  The preoperative apnea hypopnea index (AHI) and lowest SaO(2) (LSaO(2)) were 58.4-/+5.1/h and 0.650-/+0.059, respectively, which were 15.5-/+3.2/h and 0.864-/+0.064 at 6 months after surgery, respectively, showing significant changes after surgery (P<0.01). Dyspnea occurred in 2 cases after operation, intraoperative bleeding in 1 case, primary bleeding in 2 cases and hypertension crisis in 1 case.
  
  
  CONCLUSIONS
  Severe OSAHS patients are subject to great surgical risk. Application of auto-CPAP before operation can significantly improve the patients' tolerance of surgery and anesthesia, and reduce the surgical risks and preoperative complications.
authors.affiliation: Departments of Otorhinolaryngology, First People's Hospital of Foshan, Foshan 528000, China. lrhan@fsyyy.com
authors.forename: Run-han
authors.initials: RH
authors.lastname: Li
authors.forename: Yong
authors.initials: Y
authors.lastname: Zeng
authors.forename: Yue-jian
authors.initials: YJ
authors.lastname: Wang
authors.forename: Yuan-xin
authors.initials: YX
authors.lastname: Zhao
authors.forename: Wei-xiong
authors.initials: WX
authors.lastname: Chen
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
mesh_terms: D000328:Adult; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures; D010159:Palate / Q000601:surgery*; D019990:Perioperative Care / Q000379:methods*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D019651:Plastic Surgery Procedures / Q000379:methods; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery