Anterior segment ischaemia with giant cell arteritis.
METHODS
A 69-year-old male presented with bilateral blurred vision, left periocular pain, and headache. Ocular examination revealed a right optic neuropathy and left anterior segment ischaemia. An elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) raised suspicion of giant cell arteritis (GCA), which was confirmed by temporal artery biopsy. Treatment with intravenous methylprednisolone followed by a gradually reducing dose of oral prednisolone improved vision in both eyes.


CONCLUSIONS
GCA typically affects large- and medium-sized vessels. It is a recognised cause of anterior ischaemic optic neuropathy. Anterior segment ischaemia is usually caused by disease of the anterior ciliary arteries not typically affected by GCA. This case illustrates that GCA can rarely cause anterior segment ischaemia, without posterior segment involvement in the same eye.
McKillop
Elisabeth
E
Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK. b_mckillop@hotmail.com
Tejwani
Deepak
D
Weir
Cliff
C
Jay
Jeffery
J
D000368:Aged; D000869:Anterior Eye Segment / Q000098:blood supply*; D001706:Biopsy; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D004359:Drug Therapy, Combination; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D013699:Temporal Arteries / Q000473:pathology
D005938:Glucocorticoids; D002097:C-Reactive Protein; D011239:Prednisolone; D008775:Methylprednisolone