title: The effect of infection of hatched blastocyst bovine embryos with border disease and bovine viral diarrhea viruses.
abstract: The effect of infection with teratogenic viruses at early stages of pregnancy is not fully understood. This study aimed to look at the effect of infection with teratogenic viruses such as bovine viral diarrhea virus (BVDV) and border disease virus (BDV), on early stage embryos at the hatched blastocyst stage. BVDV and BDV are known to cross the placenta of infected mothers and lead to congenital defects and death of developing fetuses. This study can be a good model for better understanding the effects of other teratogenic viruses such as Rubella virus in humans.
authors.affiliation: Advanced Medical and Dental Institute, University Sains Malaysia, Penang. mmabruk03@yahoo.co.uk
authors.forename: Mohamed J E M F
authors.initials: MJ
authors.lastname: Mabruk
authors.forename: Brian
authors.initials: B
authors.lastname: Sheahan
authors.forename: Gregory
authors.initials: G
authors.lastname: Atkins
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000473:pathology / Q000821:virology*; D001882:Border Disease / Q000473:pathology / Q000821:virology*; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000473:pathology / Q000821:virology*; D002417:Cattle; D002478:Cells, Cultured; D001908:Diarrhea Viruses, Bovine Viral; D010576:Pestivirus; D012756:Sheep