Unusual cutaneous manifestation of angiocentric T-cell lymphoma: a case report.
Angiocentric T-cell lymphoma may clinically present with a broad variety of cutaneous manifestations, including papules, nodules, and ulcerated tumors, and may mimic cutaneous vasculitis and Wegener granulomatosis. Histologic diagnosis of angiocentric T-cell lymphoma also may present a challenge because of variations in the degree of cellular infiltrate and cellular atypia. The correct diagnosis is critical because of the importance of choosing the correct therapeutic modality-chemotherapy or x-ray radiation. We report a case of angiocentric T-cell lymphoma with extensive necrotic facial ulcers that responded to treatment with fludarabine, cyclophosphamide, and prednisone.
Bene
Natalie I
NI
Department of Dermatology, Roswell Park Cancer Insititute, Buffalo, New York, USA. nataliebene@yahoo.com
Zeitouni
Nathalie C
NC
Cheney
Richard
R
D005153:Facial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*