title: [Severe Graves' ophthalmopathy accompanied by myasthenia gravis].
abstract: We report a 53-year-old woman with severe Graves' ophthalmopathy accompanied by uncontrolled myasthenia gravis. She presented remarkable exophthalmos, chemosis, and restriction of eye movement. Despite plasma exchange, steroid pulse therapy, local injection of steroid, and irradiation, ocular symptoms did not ameliorate. Since optic neuropathy was seen, orbital decompression surgery was performed in the left eye. Bilateral chemosis was improved after the surgery. Five years after surgery, there was no ocular palsy in the operated left eye, but in the contralateral eye. For the good prognosis of the eye movement, orbital decompression might be recommended in the severe Graves' ophthalmopathy accompanied by the optic neuropathy and/or ophthalmoplegia with proptosis.
authors.affiliation: Division of Neurology, Department of Medicine, Shiga University of Medical Science.
authors.forename: Kengo
authors.initials: K
authors.lastname: Maeda
authors.forename: Shinji
authors.initials: S
authors.lastname: Kume
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Nishio
authors.forename: Shiro
authors.initials: S
authors.lastname: Maeda
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nishida
authors.forename: Mikio
authors.initials: M
authors.lastname: Suzuki
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakaguchi
authors.forename: Toru
authors.initials: T
authors.lastname: Kawabata
authors.forename: Osamu
authors.initials: O
authors.lastname: Hashimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Hisanaga
authors.forename: Atsunori
authors.initials: A
authors.lastname: Kashiwagi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yasuda
mesh_terms: D019299:Decompression, Surgical; D005260:Female; D049970:Graves Ophthalmopathy / Q000150:complications* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000601:surgery; D009901:Optic Nerve Diseases / Q000150:complications / Q000601:surgery; D010951:Plasma Exchange; D012720:Severity of Illness Index; D016896:Treatment Outcome