title: Postoperative results after desflurane or sevoflurane combined with remifentanil in morbidly obese patients.
abstract: BACKGROUND
  This randomized prospective study with blinded postanesthesia care unit (PACU) observers compared the recovery profiles in morbidly obese patients who received sevoflurane or desflurane for maintenance of anesthesia in combination with a remifentanil target controlled infusion (TCI).
  
  
  METHODS
  50 morbidly obese patients scheduled for laparoscopic gastric banding were included to receive BIS-guided sevoflurane or desflurane anesthesia with BIS-triggered inhalation boli in combination with remifentanil TCI. In the PACU, the following recovery scores were investigated: Modified Aldrete score, a modified Observers' Assessment of Alertness/Sedation Scale (OAA/S), pain numerical rating scale (NRS), oxygen saturation (SpO(2)) and postoperative nausea and vomiting (PONV).
  
  
  RESULTS
  OAA/S and NRS pain scores showed a similar evolution in both groups from the moment of PACU admission up to 120 minutes after admission. In both groups, patients showed no serious hypoxemia during PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group compared to the desflurane group.
  
  
  CONCLUSIONS
  No clinically relevant difference was found in recovery in the PACU between morbidly obese patients anesthetized with desflurane or sevoflurane. Both agents resulted in satisfactory recovery in morbidly obese patients.
authors.affiliation: Ghent University Hospital, Gent, Belgium. Luc.debaerdemaeker@Ugent.be
authors.forename: Luc E C
authors.initials: LE
authors.lastname: De Baerdemaeker
authors.forename: Stefan
authors.initials: S
authors.lastname: Jacobs
authors.forename: Nadia M M
authors.initials: NM
authors.lastname: Den Blauwen
authors.forename: Piet
authors.initials: P
authors.lastname: Pattyn
authors.forename: Luc L G
authors.initials: LL
authors.lastname: Herregods
authors.forename: Eric P
authors.initials: EP
authors.lastname: Mortier
authors.forename: Michel M R F
authors.initials: MM
authors.lastname: Struys
mesh_terms: D000328:Adult; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000077335:Desflurane; D005260:Female; D015391:Gastroplasty / Q000379:methods; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives*; D010535:Laparoscopy; D008297:Male; D008738:Methyl Ethers; D009767:Obesity, Morbid / Q000601:surgery; D010100:Oxygen / Q000097:blood; D010147:Pain Measurement; D010880:Piperidines; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology; D000077208:Remifentanil; D000077149:Sevoflurane; D016896:Treatment Outcome
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D010880:Piperidines; D000077149:Sevoflurane; D000077335:Desflurane; D007530:Isoflurane; D000077208:Remifentanil; D010100:Oxygen