Suppression of natural killer cell activity on Candida stellatoidea by a 50 Hz magnetic field.
Exposure to electromagnetic fields (EMF) is ubiquitous for almost all individuals living in industrialized countries. Epidemiological and laboratory studies suggest that exposure to Extremely Low Frequency (ELF) EMF increase cancer risk. The immune system functions as one of the body's main protective mechanisms, and Natural Killer (NK) cells are a subset of lymphocytes that can destroy several types of tumor cells. In this study, we investigated, NK cell activity after exposure to a 50 Hertz (Hz), 2 mT magnetic field generated by a Helmholtz Coil. Nineteen male, 10-12 week old guinea pigs were used, and NK cytotoxic activity of splenocytes was measured in vitro by natural anticandidial colorimetric index. The Mann-Whitney U test was applied for statistical analysis. NK cell cytotoxic activity was decreased in exposed compared to controls. Our data suggests that part of the immune system, the NK cell, can be suppressed by a 50 Hz magnetic field.
Canseven
Ayse G
AG
Department of Biophysics, Gazi University Medical Faculty, Ankara, Turkey. canseven@gazi.edu.tr
Seyhan
Nesrin
N
Mirshahidi
Saeid
S
Imir
Turgut
T
D000818:Animals; D002175:Candida / Q000528:radiation effects*; D003602:Cytotoxicity, Immunologic / Q000528:radiation effects*; D004574:Electromagnetic Fields; D006168:Guinea Pigs; D007694:Killer Cells, Natural / Q000276:immunology / Q000528:radiation effects*; D008297:Male; D013154:Spleen / Q000166:cytology / Q000473:pathology / Q000528:radiation effects*