[Association between microalbuminuria and arterial stiffness in hypertensive and diabetic patients].
OBJECTIVE
To investigate the relationship between microalbuminuria and arterial compliance in hypertensive and diabetes patients.


METHODS
A total of 200 patients with essential hypertension and/or diabetes were studied. Albumin/creatinine ratio (ACR) was determined. Carotid to femoral Pulse Wave Velocity (PWV), C(1) and C(2) were measured by a Complier Colson device and DO-2020, respectively.


RESULTS
(1) C(1) and C(2) were lower and PWV higher in high ACR group than in normal ACR group (P < 0.01). (2) In patients younger than 60 years, C(1) was lower and PWV higher in high ACR group than that in normal ACR group (P < 0.01). In patients older than 60 years, C(1), C(2) were lower in high ACR group than in normal ACR group.


CONCLUSIONS
The results indicated that compliance of large and small vessels in hypertensive and diabetic patients decreased with increasing ACR.
Wang
Lu-yan
LY
Department of Hypertension, People's Hospital of Peking University, Beijing 100044, China.
Sun
Ning-ling
NL
Chang
Ling
L
Liu
Xi-rong
XR
D000328:Adult; D000368:Aged; D000418:Albumins / Q000032:analysis; D000419:Albuminuria; D001158:Arteries / Q000503:physiopathology; D003404:Creatinine / Q000652:urine; D003920:Diabetes Mellitus / Q000503:physiopathology* / Q000652:urine*; D004548:Elasticity; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology* / Q000652:urine*; D008297:Male; D008875:Middle Aged
D000418:Albumins; D003404:Creatinine