Safety of adenosine stress magnetic resonance imaging using a mobile cardiac magnetic resonance system.
BACKGROUND
Contrast-enhanced magnetic resonance imaging (ceMRI) allows for the detection of ischemic heart disease. Aim of this prospective study was to show feasibility, practicability and safety of adenosine stress ceMRI in routine outpatients with a mobile scanner.


METHODS
Consecutive patients were scanned in six different cardiac outpatient centers with a 1.5 T mobile ceMRI scanner. First-pass wash-in patterns of gadolinium chelate were evaluated after three minutes of adenosine infusion. After a second bolus of gadolinium chelate myocardial late enhancement (MLE) images of the left ventricle were acquired to visualize myocardial necrosis.


RESULTS
Five hundred seventy-four patients were enrolled to the study. No major complications during examination and adenosine infusion were observed. One hundred seventy-three minor complications as temporary atrio-ventriculare blockade, mild chest pain or dyspnea and nausea were noticed. None of the complications led to further special treatment


CONCLUSIONS
This ceMRI protocol is suitable for application in outpatient settings. CeMRI stress testing using a mobile scanner in an outpatient setting is feasible and safe.
Bernhardt
Peter
P
Cardiac MRI-Center, Hospital Agatharied, Hausham, Germany. bernhardt@cardiovasc-mri.com
Steffens
Michael
M
Kleinertz
Klaus
K
Morell
Roland
R
Budde
Rainer
R
Leischik
Roman
R
Krämer
Alfred
A
Overhoff
Ulrich
U
Strohm
Oliver
O
D000241:Adenosine; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006571:Heterocyclic Compounds; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008952:Mobile Health Units; D017202:Myocardial Ischemia / Q000175:diagnosis*; D009942:Organometallic Compounds; D011446:Prospective Studies; D012449:Safety
D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; D000241:Adenosine