title: Cancer immunotherapy and preclinical studies: why we are not wasting our time with animal experiments.
abstract: Experimental research on the immune response to transplanted tumors has led to pioneering discoveries that laid many of the foundations for the current field of immunology. Experimental research in oncology has proven that murine and human tumors have antigens that are truly cancer specific. This article discusses research investigating how can antigens on cancer cells be used to help eradicate cancer.
authors.affiliation: Department of Pathology, The University of Chicago, IL 60637, USA. hszz@midway.uchicago.edu
authors.forename: Karin
authors.initials: K
authors.lastname: Schreiber
authors.forename: Donald A
authors.initials: DA
authors.lastname: Rowley
authors.forename: Gert
authors.initials: G
authors.lastname: Riethmüller
authors.forename: Hans
authors.initials: H
authors.lastname: Schreiber
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D009369:Neoplasms / Q000628:therapy*; D036302:Therapeutic Human Experimentation