title: [Pneumonia - pathogen-based or constellation-based therapy?].
abstract: Community-acquired pneumonia is one of the most frequent infectious diseases with high morbidity and mortality. Early and sufficient antibiotic treatment is crucial for the prognosis of the patient. The underlying pathogens are mostly unknown at the onset of symptoms. The choice of antibiotic treatment depends on the suspected pathogens, derived from the typical germs and the typical resistances in a certain area. In addition, individual risk factors, such as age, severity of the diseases, comorbidities, and previous antibiotic treatment have a major impact on the probability of dying for an individual patient. These factors must be considered at the beginning of any treatment. Pathogen-based treatment has to be switched to constellation-based treatment.
authors.affiliation: Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13 353 Berlin. antje.kuhnke@charite.de
authors.forename: A
authors.initials: A
authors.lastname: Kuhnke
authors.forename: T
authors.initials: T
authors.lastname: Welte
authors.forename: N
authors.initials: N
authors.lastname: Suttorp
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D000998:Antiviral Agents / Q000008:administration & dosage*; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology / Q000821:virology; D006801:Humans; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000821:virology*; D011024:Pneumonia, Viral / Q000188:drug therapy* / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents