title: [Allele variants of Borrelia afzelii found by sequencing of the chromosome gene p66].
abstract: Sequencing of gene p66 fragments of 246-337 p.b. was performed in 45 isolates of Aorrelia afzelii isolated from different transmitting agents and reservoir hosts within the habitation area of the spirochaeta. At least seven allele variants of the pathogenic agent were found indifferent natural foci of the disease. The extent of similarity between the nucleotide sequences of the isolates of the same allele variant was 99.9-100%; the extent of similarity between different allele variants was 98.9-99.7%. It was found that the majority of genovariants of A. afzelii (with respect to 5S-23S) incorporated several different allele variants of gene p66, all allele variants being found in the two genogroups (VS461 and NT28) of the pathogenic agent.
authors.forename: I A
authors.initials: IA
authors.lastname: Fadeeva
authors.forename: E I
authors.initials: EI
authors.lastname: Korenberg
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Andreĭchuk
authors.forename: A L
authors.initials: AL
authors.lastname: Markov
authors.forename: N B
authors.initials: NB
authors.lastname: Gorelova
mesh_terms: D000483:Alleles; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D001483:Base Sequence; D015748:Borrelia burgdorferi Group / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D002876:Chromosomes, Bacterial; D005787:Gene Frequency; D008193:Lyme Disease / Q000382:microbiology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D018272:Porins / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D001426:Bacterial Proteins; C107893:Oms66 protein, Borrelia; D018272:Porins