title: Development of antibodies to Burkholderia pseudomallei during childhood in melioidosis-endemic northeast Thailand.
abstract: A cross-sectional serological survey of 2,214 children living in northeast Thailand was conducted to define the antibody response to Burkholderia pseudomallei from birth to 14 years. There was a sharp rise in detectable antibodies from birth to 4 years followed by reactivity in approximately 60-70% of children thereafter.
authors.affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors.forename: Vanaporn
authors.initials: V
authors.lastname: Wuthiekanun
authors.forename: Wirongrong
authors.initials: W
authors.lastname: Chierakul
authors.forename: Sayan
authors.initials: S
authors.lastname: Langa
authors.forename: Wipada
authors.initials: W
authors.lastname: Chaowagul
authors.forename: Chanathip
authors.initials: C
authors.lastname: Panpitpat
authors.forename: Penchan
authors.initials: P
authors.lastname: Saipan
authors.forename: Thaksinaporn
authors.initials: T
authors.lastname: Thoujaikong
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Day
authors.forename: Sharon J
authors.initials: SJ
authors.lastname: Peacock
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000907:Antibodies, Bacterial / Q000097:blood* / Q000276:immunology; D016957:Burkholderia pseudomallei / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008554:Melioidosis / Q000453:epidemiology / Q000276:immunology*; D015995:Prevalence; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D013785:Thailand / Q000453:epidemiology; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial