title: Multinucleation and cleavage of embryos derived from in vitro-matured oocytes.
abstract: In patients with polycystic ovary syndrome (PCOS), the proportion of optimal embryos-blastomere number and fragmentation rate-derived from in vitro-matured oocytes after the hCG priming protocol was higher (43.3%) than the proportion of optimal embryos derived from oocyte in vitro maturation with the FSH priming protocol (11.1%). The embryos derived from in vitro-matured oocytes after the hCG priming protocol also showed a lower incidence of multinucleated blastomeres. Pregnancies were recorded only in the hCG primed patients.
authors.affiliation: Department of Reproductive Medicine and Gynecologic Endocrinology, Maribor Teaching Hospital, Maribor, Slovenia.
authors.forename: Veljko
authors.initials: V
authors.lastname: Vlaisavljević
authors.forename: Mojca
authors.initials: M
authors.lastname: Cizek-Sajko
authors.forename: Vilma
authors.initials: V
authors.lastname: Kovac
mesh_terms: D000328:Adult; D001755:Blastocyst / Q000166:cytology / Q000502:physiology; D001757:Blastomeres / Q000166:cytology / Q000648:ultrastructure*; D002452:Cell Count; D002467:Cell Nucleus / Q000648:ultrastructure*; D002478:Cells, Cultured; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D002970:Cleavage Stage, Ovum / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D009865:Oocytes / Q000187:drug effects; D009866:Oogenesis; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic
chemical_list: D006063:Chorionic Gonadotropin; D005640:Follicle Stimulating Hormone