title: Histological and fluorescence microscopic examination of the bone/implant interface in orthodontic miniscrews (Mondeal).
abstract: The temporary nature of orthodontic implants demands optimisation of size and design in order to minimise damage and risk to the patient. Slender and shorter miniscrews offer the advantage over conventional implants of easier and more ubiquitous positioning with minimised risk of injury to neighbouring anatomical structures such as tooth roots, nerves or vessels. The question is raised, however, as to what extent these advantages are gained at the price of diminished stability or a more unfavourable bone interface. In order to evaluate the screw/bone interface, 14 orthodontic miniscrews (Mondeal Medical Systems, diameter: 1.5 mm, length: 9 mm) were inserted into the right and left mandibles of 7 pigs (Sus scrofa domestica). Bone fluorochromes were administered in a defined order for polychrome sequencing. The samples gathered after 70 days were analysed using histological techniques and fluorescence microscopy. The lower part of the self-tapping thread displayed undisturbed bone apposition. Fluorescence microscopy revealed remodelling and bone apposition within the thread grooves.
authors.affiliation: Clinic for Orthodontics and Preventive and Paediatric Dentistry, University of Greifswald Dental School, Greifswald, Germany. gedrange@uni-greifswald.de
authors.forename: T
authors.initials: T
authors.lastname: Gedrange
authors.forename: P
authors.initials: P
authors.lastname: Proff
authors.forename: T
authors.initials: T
authors.lastname: Bayerlein
authors.forename: P
authors.initials: P
authors.lastname: Landsberger
authors.forename: S
authors.initials: S
authors.lastname: Dietze
authors.forename: J
authors.initials: J
authors.lastname: Fanghänel
mesh_terms: D000818:Animals; D001863:Bone Screws; D015921:Dental Implants; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008856:Microscopy, Fluorescence / Q000379:methods*; D023421:Models, Animal; D016382:Orthodontic Appliance Design / Q000295:instrumentation* / Q000379:methods; D016348:Osseointegration; D013552:Swine
chemical_list: D015921:Dental Implants