A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis.
Here, we describe a case of severe pancreatitis in overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in an adult female patient. Treatment with plasmapheresis and high-dose prednisone successfully saved her life and led to remission of the pancreatitis. This is the first case report of severe acute pancreatitis in the setting of overlap syndrome of SLE and SSc. The advantages and disadvantages of the use of corticosteroids are discussed.
Suzuki
Yukie
Y
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.
Okamoto
Hiroshi
H
Koizumi
Kyoko
K
Tateishi
Mutsuto
M
Hara
Masako
M
Kamatani
Naoyuki
N
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D016670:Gabexate / Q000008:administration & dosage; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects; D010195:Pancreatitis / Q000209:etiology / Q000628:therapy; D010956:Plasmapheresis / Q000379:methods*; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D012595:Scleroderma, Systemic / Q000150:complications*; D015842:Serine Proteinase Inhibitors / Q000008:administration & dosage; D013577:Syndrome
D000893:Anti-Inflammatory Agents; D015842:Serine Proteinase Inhibitors; D016670:Gabexate; D011241:Prednisone; D008775:Methylprednisolone