title: Serum thyroid hormone concentrations and thyroglobulin autoantibodies in trained and non-trained healthy whippets.
abstract: Numerous factors including non-thyroidal systemic diseases and drug administration can significantly alter canine thyroid function test results. Furthermore, the importance of breed specific variations has probably been underestimated. In this study, total thyroxine (TT4), free thyroxine (FT4), canine endogenous thyroid stimulating hormone (cTSH) serum concentrations and thyroglobulin autoantibodies (TgAA) were determined in a population of healthy whippets and compared to a control group of different breeds. Mean TT4 values were significantly lower in the whippets but no significant differences were seen between whippets and control dogs for FT4 and for cTSH. The prevalence of serum TgAA in the whippets was 2%, and this was not significantly different from the controls. The results suggest a breed variation for TT4, but not for FT4, cTSH and TgAA serum concentrations in whippets. Serum thyroid hormone concentrations were also compared between trained and non-trained whippets and it was concluded that regular training did not seem to have any significant influence.
authors.affiliation: Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. cindyvangeffen@hotmail.com
authors.forename: Cindy
authors.initials: C
authors.lastname: van Geffen
authors.forename: Valérie
authors.initials: V
authors.lastname: Bavegems
authors.forename: Luc
authors.initials: L
authors.lastname: Duchateau
authors.forename: Katrien
authors.initials: K
authors.lastname: De Roover
authors.forename: Sylvie
authors.initials: S
authors.lastname: Daminet
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000097:blood; D001947:Breeding; D004285:Dogs / Q000097:blood / Q000235:genetics / Q000502:physiology*; D005260:Female; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D013954:Thyroglobulin / Q000276:immunology; D013960:Thyroid Function Tests / Q000662:veterinary; D013961:Thyroid Gland / Q000502:physiology*; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D001323:Autoantibodies; D013963:Thyroid Hormones; D013972:Thyrotropin; D013954:Thyroglobulin; D013974:Thyroxine