title: [An investigation for genetic polymorphisms of 10 STR loci on chromosome X of Chinese Hui nationality population in Ningxia region of China].
abstract: OBJECTIVE
  To investigate the alleles and genotypes frequency of 10 short tandem repeat (STR) loci (DXS101, DXS6789, DXS6799, DXS6804, DXS7130, DXS7132, DXS7133, DXS7423, HPRTB, DXS8378) on X chromosome of Chinese Hui nationality population.
  
  
  METHODS
  The study of 10 STR loci was performed by using the techniques of PCR, polyacylamide gel electrophoresis and silver staining.
  
  
  RESULTS
  Among unrelated Hui individuals, the allele numbers of 10 STR loci DXS101, DXS6789, DXS6799, DXS6804, DXS7130, DXS7132, DXS7133, DXS7423, HPRTB, DXS8378 were 9, 8, 4, 6, 6, 6, 4, 4, 5 or 5 respectively; the numbers of genotypes were 17, 22, 7, 14, 14, 15, 6, 7, 12 or 8 respectively. The distribution of genotypes from these 10 STR systems fitted the Hardy-Weinberg equilibrium (P> 0.05). Polymorphisms information content of 10 STR loci, except for DXS7133 (0.48) and DXS7423 (0.48), ranged from 0.54 (DXS6799) to 0.80 (DXS6789); the power of discrimination were from 0.89 (DXS7133, DXS7423) to 0.99 (DXS6789, DXS7132, DXS101).
  
  
  CONCLUSIONS
  The loci of 10 STR on chromosome X are appropriate for individual identification, paternity testing involving a female child and for study on related disease.
authors.affiliation: Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xioan Jiaotong University, Xioan, Shaanxi, 710061, PR China.
authors.forename: Xue
authors.initials: X
authors.lastname: Feng
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
authors.forename: Ya
authors.initials: Y
authors.lastname: Tuo
authors.forename: Bing
authors.initials: B
authors.lastname: Yu
authors.forename: Sheng-bin
authors.initials: SB
authors.lastname: Li
mesh_terms: D000483:Alleles; D002648:Child; D002681:China; D041321:Chromosomes, Human, X / Q000235:genetics*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*