title: Macroscopic and histological effects of magnetic field exposition in the process of tissue reparation in Wistar rats.
abstract: Exposing body tissue, in vivo, to a magnetic field promotes metabolic alterations in the cell membrane's permeability and in the apoptosis phenomenon. This aim of the study was to investigate magnetic field interactions in the process of tissue repair in rats. Twenty-four male Wistar rats, weighing 200-350 g, were assigned to one of the three different groups: Control (without exposure to the magnetic field), South Pole (with exposure to the South magnetic field), and North Pole (with exposure to the north magnetic field). The intensity of the magnetic field used was 1,600 G. All the animals were anesthetized and immobilized on a surgical board in order to receive circular wounds. The size of the wounds was measured by a milimetric paquimeter. For the histological study, the tissues were fixed in paraffin and colored with hematoxylin and eosin. Wound size data were submitted to one-way analysis of variance (ANOVA) and to the test of Student-Newman-Keuls when appropriated. The results of day 5 (F (2,23):F (3,84); P < 0.05), day 10 (F (2,23):F (8,89); P < 0.05), and day 15 (F (2,23):F (7,88); P < 0.05) revealed a significant reduction between the size of the wounds of both North and South groups when compared to Control group. Our data suggest that chronic exposure to a magnetic field of 1,600 G can accelerate the speed of tissue repair in rats.
authors.affiliation: Graduation Program in Physiotherapy, University of Franca, Sao Paulo, Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Bertolino
authors.forename: Aldo
authors.initials: A
authors.lastname: de Freitas Braga
authors.forename: Kelline
authors.initials: K
authors.lastname: de Oliveira Lima do Couto Rosa
authors.forename: Lacy Cardoso
authors.initials: LC
authors.lastname: de Brito Junior
authors.forename: João Eduardo
authors.initials: JE
authors.lastname: de Araujo
mesh_terms: D000818:Animals; D002921:Cicatrix / Q000473:pathology*; D008280:Magnetics; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014945:Wound Healing / Q000502:physiology*