title: [Invasive pneumococcal infections in patients with primary immunodeficiency disorders].
abstract: The authors review the immunopathology of invasive pneumococcal infections in patients with primary immunodeficiency diseases, with particular emphasis on selective anti-polysaccharide antibody deficiency. They summarize current knowledge on the molecular mechanisms and clinical manifestations of host defense against Str. pneumoniae.
authors.affiliation: Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Infektológiai és Gyermekimmunológiai Tanszék, Debrecen.
authors.forename: Melinda
authors.initials: M
authors.lastname: Erdos
authors.forename: László
authors.initials: L
authors.lastname: Maródi
mesh_terms: D000907:Antibodies, Bacterial / Q000378:metabolism*; D001402:B-Lymphocytes / Q000276:immunology; D003165:Complement System Proteins / Q000172:deficiency; D006801:Humans; D016867:Immunocompromised Host; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000276:immunology*; D010586:Phagocytes / Q000276:immunology; D011008:Pneumococcal Infections / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000821:virology; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013296:Streptococcus pneumoniae; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D011135:Polysaccharides, Bacterial; D003165:Complement System Proteins