[Musculoskeletal pain as the most prominent feature in myotonic dystrophy type 2].
BACKGROUND
Myotonic dystrophy type 2/proximal myotonic myopathy (DM 2/PROMM) is an autosomal dominant multisystem disorder characterized by proximal muscle weakness, myotonia and musculoskeletal pain.


METHODS
We describe five patients with DM 2/PROMM in whom musculoskeletal pain was the most prominent feature. We used the McGill Pain Questionnaire for standardized pain assessment.


RESULTS
The patients reported multiple types of musculoskeletal pain including tenderness, cold-enhanced and exercise-related musculoskeletal pain. Exercise-induced or -enhanced musculoskeletal pain was indicated as the most disabling feature.


CONCLUSIONS
Myotonic dystrophy type 2 should be considered as one of the differential diagnoses in patients with musculoskeletal pain. Family history and laboratory tests provide critical diagnostic clues.
George
A
A
Neurologische Klinik und Poliklinik, Universitätsklinikum Würzburg. a.george@ion.ucl.ac.uk
Schneider-Gold
C
C
Reiners
K
K
Sommer
C
C
D000328:Adult; D003937:Diagnosis, Differential; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009141:Musculoskeletal System / Q000503:physiopathology; D020967:Myotonic Disorders / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology; D010146:Pain / Q000175:diagnosis* / Q000503:physiopathology; D010147:Pain Measurement