Steroid sparing effect of a herbal preparation in steroid-dependent nephrotic syndrome.
Investigations on plants are revealing the potential therapeutic benefits of medicinal herbs in treating immunological disorders. Nephrotic syndrome has emerged as an immunological disorder. Steroid dependence poses a therapeutic challenge in the management of nephrotic syndrome. Our pilot study compares the efficacy of an ayurvedic polyherbal preparation 'Shathavaryadi Yoga (NS001)' with oral cyclophosphamide in maintaining remission in steroid-dependent nephrotic syndrome.
Iyengar
Arpana
A
Childrens' Kidney Care Center, Department of Paediatrics, St Johns Medical College Hospital, Bangalore, 560034, India.
Damle
Hrishikesh
H
Kulkarni
Chanda
C
Damle
Latha
L
Phadke
Kishore
K
D000328:Adult; D000368:Aged; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D010865:Pilot Projects; D028321:Plant Preparations / Q000627:therapeutic use*; D012008:Recurrence; D012074:Remission Induction; D016896:Treatment Outcome
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D028321:Plant Preparations; D003520:Cyclophosphamide