Isolation of Lawsonia intracellularis in Korea and reproduction of proliferative enteropathy in pigs and hamsters.
Lawsonia intracellularis (L. intracellularis) was isolated from a Korean pig suffering acute proliferative enteropathy. In vitro culture conditions of L. intracellularis were established in McCoy cells. Pigs and hamsters experimentally infected with the pure culture of L. intracellularis reproduced clinical signs and intestinal lesions of proliferative enteropathy. The presence of L. intracellularis in the intestinal lesions was confirmed by immunohistochemistry with L. intracellularis-specific monoclonal antibodies.
Yeh
Jung-Yong
JY
National Veterinary Research and Quarantine Service, Seoul, Korea.
Kim
Tae-Jong
TJ
Park
Seung-Yong
SY
Song
Chang-Seon
CS
Yoon
Yong-Dhuk
YD
Kim
Soo-Ki
SK
Lee
Joong-Bok
JB
Choi
In-Soo
IS
D000818:Animals; D000911:Antibodies, Monoclonal; D006224:Cricetinae; D045824:Desulfovibrionaceae Infections / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D007082:Ileum; D007150:Immunohistochemistry / Q000662:veterinary; D007410:Intestinal Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D007413:Intestinal Mucosa / Q000382:microbiology; D007723:Korea; D020639:Lawsonia Bacteria / Q000302:isolation & purification* / Q000472:pathogenicity*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology
D000911:Antibodies, Monoclonal