[The role of portal hypertension and colloid-osmotic blood pressure in the pathogenesis of ascitis in patients with hepatic cyrrhosis].
The subjects of the study were 27 patients with hepatic cirrhosis and portal hypertension syndrome. Laboratory and instrumental diagnostic methods routinely used in this pathology were applied: calculation of colloid-osmotic pressure; portal pressure measurement, intraoperationally and using phlebohepatomanometry. The data were processed using STATISTIKA program. The results show that: 1. Ascitic syndrome manifestations do not depend on either the pressure in the v. porta nor oncotic pressure (insignificant difference between the groups); 2. Filtration gradient (FG), which is a physiological variable that determine the liquid movement in splanchnic capillaries, was significantly higher in ascitic patients (p < 0.05); FG correlates with the presence of ascitis (r = 0.5, p < 0.05); 3. FG after portacaval shunting facilitates the resolution of ascitis.
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Basov
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D000328:Adult; D001201:Ascites / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D006975:Hypertension, Portal / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D008103:Liver Cirrhosis / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D008297:Male; D009997:Osmotic Pressure; D011379:Prognosis; D012189:Retrospective Studies