Postoperative results after desflurane or sevoflurane combined with remifentanil in morbidly obese patients.
BACKGROUND
This randomized prospective study with blinded postanesthesia care unit (PACU) observers compared the recovery profiles in morbidly obese patients who received sevoflurane or desflurane for maintenance of anesthesia in combination with a remifentanil target controlled infusion (TCI).


METHODS
50 morbidly obese patients scheduled for laparoscopic gastric banding were included to receive BIS-guided sevoflurane or desflurane anesthesia with BIS-triggered inhalation boli in combination with remifentanil TCI. In the PACU, the following recovery scores were investigated: Modified Aldrete score, a modified Observers' Assessment of Alertness/Sedation Scale (OAA/S), pain numerical rating scale (NRS), oxygen saturation (SpO(2)) and postoperative nausea and vomiting (PONV).


RESULTS
OAA/S and NRS pain scores showed a similar evolution in both groups from the moment of PACU admission up to 120 minutes after admission. In both groups, patients showed no serious hypoxemia during PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group compared to the desflurane group.


CONCLUSIONS
No clinically relevant difference was found in recovery in the PACU between morbidly obese patients anesthetized with desflurane or sevoflurane. Both agents resulted in satisfactory recovery in morbidly obese patients.
De Baerdemaeker
Luc E C
LE
Ghent University Hospital, Gent, Belgium. Luc.debaerdemaeker@Ugent.be
Jacobs
Stefan
S
Den Blauwen
Nadia M M
NM
Pattyn
Piet
P
Herregods
Luc L G
LL
Mortier
Eric P
EP
Struys
Michel M R F
MM
D000328:Adult; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000077335:Desflurane; D005260:Female; D015391:Gastroplasty / Q000379:methods; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives*; D010535:Laparoscopy; D008297:Male; D008738:Methyl Ethers; D009767:Obesity, Morbid / Q000601:surgery; D010100:Oxygen / Q000097:blood; D010147:Pain Measurement; D010880:Piperidines; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology; D000077208:Remifentanil; D000077149:Sevoflurane; D016896:Treatment Outcome
D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D010880:Piperidines; D000077149:Sevoflurane; D000077335:Desflurane; D007530:Isoflurane; D000077208:Remifentanil; D010100:Oxygen