title: Development of diffuse large B cell lymphoma during the maintenance therapy for B-lineage acute lymphoblastic leukemia.
abstract: Non-Hodgkin lymphoma (NHL) is a very rare complication of acute lymphoblastic leukemia (ALL). A Japanese boy presented with B-lineage ALL at the age of 2.5. He was treated with chemotherapy for standard-risk ALL. While he was receiving maintenance treatment 2 years and 9 months after the diagnosis of ALL, diffuse large B cell lymphoma (DLBL) was diagnosed from a biopsy of an abdominal mass. DLBL was treated by surgical resection followed by chemotherapy for 6 months. The patient has been free from the recurrence of ALL or DLBL for 16 months after the development of DLBL.
authors.affiliation: Department of Pediatrics, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo 104-8560, Japan.
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Atsushi
authors.initials: A
authors.lastname: Manabe
authors.forename: Chiaki
authors.initials: C
authors.lastname: Aoyama
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kamiya
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Morimoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsufuji
authors.forename: Koyu
authors.initials: K
authors.lastname: Suzuki
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hori
authors.forename: Masahito
authors.initials: M
authors.lastname: Tsurusawa
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Kiyokawa
authors.forename: Fujimoto
authors.initials: F
authors.lastname: Junichiro
authors.forename: Ryota
authors.initials: R
authors.lastname: Hosoya
mesh_terms: D002675:Child, Preschool; D006801:Humans; D016393:Lymphoma, B-Cell / Q000209:etiology* / Q000628:therapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000628:therapy; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*