title: [Lung transplantation in the treatment of ventilator dependent end-stage lung diseases: report of three cases].
abstract: OBJECTIVE
  To investigate the perioperative management, recipient selection of end-stage lung diseases dependent on ventilator, and the strategy of ventilator weaning.
  
  
  METHODS
  Fifteen patients underwent lung transplantation in our hospital from 2002 to 2005. Of them, three were dependent on ventilator for 89, 120 and 107 days respectively because of end-stage pulmonary emphysema before operation. Single-lung transplantation was performed in one patient and sequential bilateral single-lung transplantations were performed in two patients without extracorporeal circulation.
  
  
  RESULTS
  The three patients were weaned from ventilator in the sixth, eleventh and twenty second day respectively after operation. They were discharged from hospital 71 d, 41 d, and 67 d respectively after operation. They had been followed up for 22, 4, and 2 months respectively before this analysis. Their quality of life improved significantly.
  
  
  CONCLUSIONS
  Lung transplantation is effective for the treatment of ventilator dependent end-stage lung diseases.
authors.affiliation: Center of Lung Transplant, Fifth People's Hospital of Wuxi, Jiangsu 214073, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Chen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yu
authors.forename: Min-yu
authors.initials: MY
authors.lastname: Yuan
authors.forename: Xiao-chuan
authors.initials: XC
authors.lastname: Cui
authors.forename: Xiu-fen
authors.initials: XF
authors.lastname: Qian
authors.forename: Jian-rong
authors.initials: JR
authors.lastname: Zhu
authors.forename: Ming-hua
authors.initials: MH
authors.lastname: Lu
authors.forename: Guo-chu
authors.initials: GC
authors.lastname: Lu
mesh_terms: D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000601:surgery*; D012122:Ventilators, Mechanical / Q000009:adverse effects*