[Inhibiton of conjugated linoleic acid isomers on the proliferation of tumor cells].
OBJECTIVE
To study the effect of five conjugated linoleic acid isomers on the proliferation of human tumor cell AGS and Bel7402.


METHODS
AGS, Bel7402 and Lovo cells incubated in vitro were used as model. The cell visibility was investigated after treatment with conjugated linoleic acid (CLA).


RESULTS
All the five isomers had inhibitory ability to AGS, Bel7402 and Lovo cell proliferation, and the effect on AGS was more effective than that on Bel7402 and Lovo. The inhibitory effect was dose-dependent.


CONCLUSIONS
The five isomers of CLA exhibited proliferation inhibitory effect on the tumor cell of AGS and Be17402.
Song
Lin-liang
LL
College of Food Science & Nutritional Technology, China Agricultural University, Beijing, China.
Luo
Yun-bo
YB
Shi
Jie-ping
JP
D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007536:Isomerism; D044243:Linoleic Acids, Conjugated / Q000494:pharmacology*; D008113:Liver Neoplasms / Q000473:pathology; D009369:Neoplasms / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology
D044243:Linoleic Acids, Conjugated