title: Squamous cell carcinoma of colon and rectum.
abstract: Primary squamous cell carcinoma SCC of the colon and rectum is a rare malignancy. Less than 100 cases have been reported in literature. We report 2 cases of pure SCC involving the rectum and sigmoid colon. A review of literature has been made starting from the first report in 1919 to the present. We have examined the theories regarding the etiology, available treatment modalities, and prognosis for this variant of colorectal carcinoma. We conclude that this tumor presents later than adenocarcinoma and follows an aggressive course. With a greater awareness among surgeons and pathologists, more cases may become known leading to a better estimation of prevalence and clinicopathological behavior of this tumor.
authors.affiliation: Department of Surgery, University Unit, Riyadh Medical Complex, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors.forename: Fraz
authors.initials: F
authors.lastname: Fahim
authors.forename: Saleh M
authors.initials: SM
authors.lastname: Al-Salamah
authors.forename: Muhammad K
authors.initials: MK
authors.lastname: Alam
authors.forename: Muhammad H
authors.initials: MH
authors.lastname: Al-Akeely
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D012809:Colon, Sigmoid; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D003113:Colonoscopy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*