Paradoxical deterioration during the course of antituberculous treatment.
Paradoxical deterioration during antituberculous therapy is defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. Although it has frequently been reported for patients infected with human immunodeficiency virus (HIV), it can also be seen in HIV-negative patients. Here, we present a case of miliary tuberculosis in a patient who clinically deteriorates after antituberculous treatment, and discuss this confusing entity under the light of the pertinent literature.
Onal
Ibrahim Koral
IK
Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey. karalonal@yahoo.com
Bayraktar
Yusuf
Y
Unal
Serhat
S
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018450:Disease Progression; D006801:Humans; D008297:Male; D017211:Treatment Failure; D014391:Tuberculosis, Miliary / Q000188:drug therapy* / Q000503:physiopathology
D000995:Antitubercular Agents