Functionalized mesoporous silicates for the removal of ruthenium from reaction mixtures.
[reaction: see text] The removal of residual ruthenium after olefin metathesis reactions and asymmetric hydrogenations has been described using amine-functionalized mesoporous silicates. Aminopropyltriethoxy silane-derivatized silicates were found to be the most effective. More than 99.99% of RuCl(3) could be removed in a single treatment. Scavenging of Ru after metathesis reactions using a Grubbs generation 1 catalyst gave a product with concentrations of less than 10 microg/5 mg after two treatments with amine-modified silica. Most importantly, no chromatography was required.
McEleney
Kevin
K
Department of Chemistry, Queen's University, Kingston, Ontario, Canada.
Allen
Daryl P
DP
Holliday
Alison E
AE
Crudden
Cathleen M
CM