No association between the Clara cell secretory protein (CC16) gene polymorphism and personality traits.
Clara cell secretory protein (CC16) is an anti-inflammatory protein expressed in the respiratory tract. Several studies have suggested the association between CC16 and mental disturbances, such as schizophrenia, depression, and post-traumatic stress disorder. In the present study, we investigated the association between the CC16 gene A38G polymorphism and personality traits in 214 healthy Japanese subjects. Personality traits were evaluated by using the Revised NEO Personality Inventory (NEO PI-R) and the State-Trait Anxiety Inventory (STAI). As a result, no significant association was observed between the genotypes and the scores of the NEO PI-R or the STAI. The present results suggest that CC16 may not have a major role in the development of personality traits.
Tochigi
Mamoru
M
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan.
Otowa
Takeshi
T
Hibino
Hiroyuki
H
Kato
Chieko
C
Marui
Tetsuya
T
Ohtani
Toshiyuki
T
Umekage
Tadashi
T
Kato
Nobumasa
N
Sasaki
Tsukasa
T
D000328:Adult; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D010551:Personality / Q000235:genetics*; D010556:Personality Tests; D011110:Polymorphism, Genetic / Q000235:genetics*; D011569:Psychiatric Status Rating Scales; D014598:Uteroglobin / Q000235:genetics*
C556389:SCGB1A1 protein, human; D014598:Uteroglobin