title: New MR techniques for the detection of liver metastases.
abstract: It is well established that hepatic resection improves the long-term prognosis of many patients with liver metastases. However, incomplete resection does not prolong survival, so knowledge of the exact extent of intra-hepatic disease is crucially important in determining patient management and outcome. MR imaging is well recognised as one of the most sensitive methods for detecting metastases. Recent developments in gradient coil design, the use of body phased array coils and the availability of novel MR contrast agents have resulted in MR being recognised as the pre-operative standard in this group of patients. However, diagnostic efficacy is extremely dependent on the choice and optimisation of pulse sequences and the appropriate use of MR contrast agents. This article reviews current MR imaging techniques for the detection and characterisation of metastases and discusses the relative capability of different techniques for detecting small lesions.
authors.affiliation: Department of Clinical Radiology, St James's University Hospital, Leeds, UK. janice.ward@leedsth.nhs.uk
authors.forename: J
authors.initials: J
authors.lastname: Ward
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary*; D016477:Artifacts; D015179:Colorectal Neoplasms / Q000473:pathology*; D003287:Contrast Media; D003560:Cysts / Q000473:pathology; D004867:Equipment Design; D005234:Fatty Liver / Q000139:chemically induced / Q000473:pathology; D005544:Forecasting; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D021621:Imaging, Three-Dimensional; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008536:Meglumine / Q000031:analogs & derivatives; D009942:Organometallic Compounds
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C073590:gadolinium ethoxybenzyl DTPA; C064572:gadobenic acid; D008536:Meglumine; D005682:Gadolinium; D019786:Gadolinium DTPA