title: Tithoniamarin and tithoniamide: a structurally unique isocoumarin dimer and a new ceramide from Tithonia diversifolia.
abstract: Tithoniamarin (1), a new isocoumarin dimer and a new ceramide, named tithoniamide (2a), have been isolated from Tithonia diversifolia, in addition to the known beta-sitosterol and beta-sitosterol glucopyranoside. The structures were elucidated on the basis of spectroscopic and chemical evidence. Preliminary studies showed that 1 has antifungal and herbicidal activities against Microbotryum violaceum and Chlorella fusca.
authors.affiliation: Department of Organic Chemistry, Faculty of Science, Yaounde University I, PO Box 812, Yaounde, Cameroon.
authors.forename: Meffo
authors.initials: M
authors.lastname: Yemele Bouberte
authors.forename: Karsten
authors.initials: K
authors.lastname: Krohn
authors.forename: Hidayat
authors.initials: H
authors.lastname: Hussain
authors.forename: Etienne
authors.initials: E
authors.lastname: Dongo
authors.forename: Barbara
authors.initials: B
authors.lastname: Schulz
authors.forename: Qunxiu
authors.initials: Q
authors.lastname: Hu
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002518:Ceramides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D035264:Flowers / Q000737:chemistry; D049934:Isocoumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D002518:Ceramides; D049934:Isocoumarins