[In vitro effects of antiviral drugs on the reproduction of highly pathogenic influenza A/H5N1 virus strains that induce epizooty among poultry in the summer of 2005].
Commercial drugs, such as rimantadine, amantadine, rivabirine, and arbidole, are effective in suppressing the in vitro reproduction of highly pathogenic avian influenza A/H5N1 viruses. The study has used a porcine embryonic renal cell line and the highly pathogenic A/Duck/Novosibirsk/56/05 (H5N1) strain from a sick domestic duck (Anas platyrhynchos domesticus) (Chany Lake environs, Novosibirsk Region).
L'vov
D K
DK
Fediakina
I T
IT
Shchelkanov
M Iu
MIu
Prilipov
A G
AG
Deriabin
P G
PG
Galegov
G A
GA
D000547:Amantadine / Q000494:pharmacology*; D000818:Animals; D000829:Animals, Domestic; D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D004196:Disease Outbreaks; D004305:Dose-Response Relationship, Drug; D004372:Ducks; D007211:Indoles / Q000494:pharmacology*; D053124:Influenza A Virus, H5N1 Subtype / Q000187:drug effects* / Q000502:physiology; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology; D007668:Kidney; D008826:Microbial Sensitivity Tests; D011200:Poultry; D012254:Ribavirin / Q000494:pharmacology*; D012299:Rimantadine / Q000494:pharmacology*; D012800:Siberia / Q000453:epidemiology; D013552:Swine; D014779:Virus Replication / Q000187:drug effects; D013440:Sulfides
D000547:Amantadine; D000998:Antiviral Agents; D007211:Indoles; D012254:Ribavirin; D012299:Rimantadine; C086979:umifenovir; D013440:Sulfides