title: Comparison of the BACTEC 9240 and BacT/Alert blood culture systems for detection of bacterial contamination in platelet concentrates.
abstract: The BACTEC 9240 blood culture system with a standard aerobic medium, Plus Aerobic/F, was compared to the BacT/Alert system with a platelet-specific medium, BPA, as a means for detecting bacterial contamination of platelet preparations. One hundred thirteen platelet units seeded with low levels of different bacteria were examined with both systems. In 93 instances, growth was detected first in the BACTEC system; in 12 cases, growth registered first in the BacT/Alert system. Among all comparisons, growth was detected, on average, 1.7 h sooner with the BACTEC system. The differences in length of time to detection were statistically significant.
authors.affiliation: Division of Clinical Microbiology and Transfusion Medicine, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
authors.forename: Stefan
authors.initials: S
authors.lastname: Riedel
authors.forename: Gregory
authors.initials: G
authors.lastname: Siwek
authors.forename: Susan E
authors.initials: SE
authors.lastname: Beekmann
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Richter
authors.forename: Thomas
authors.initials: T
authors.lastname: Raife
authors.forename: Gary V
authors.initials: GV
authors.lastname: Doern
mesh_terms: D016470:Bacteremia / Q000382:microbiology* / Q000517:prevention & control; D001419:Bacteria / Q000254:growth & development / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000382:microbiology / Q000517:prevention & control; D001431:Bacteriological Techniques / Q000592:standards; D001769:Blood / Q000382:microbiology; D001792:Blood Platelets / Q000166:cytology / Q000382:microbiology*; D002478:Cells, Cultured; D003470:Culture Media; D004340:Drug Contamination / Q000517:prevention & control; D006801:Humans; D017713:Platelet Transfusion / Q000009:adverse effects
chemical_list: D003470:Culture Media