title: [Establishment of a pig model of chronic ally enhanced external counterpulsation].
abstract: OBJECTIVE
  To establish a pig model of chronic external counterpulsation.
  
  
  METHODS
  Twelve pigs were anaesthetized with sodium pentobarbital (< or =30 mg/kg.b.w.) and 846 mixture (< or =0.1 ml/kg.b.w.) and counterpulsed in a lateral position for 2 h every two days (totally 36 h) with 0.025 to 0.04 MPa/cm(2) pressure.
  
  
  RESULTS
  External counterpulsation was successfully completed in all the animals. Combined administration of sodium pentobarbital and 846 mixture resulted in good anesthetic effect with reduced anesthetic dosage and minimal side effect on the viscera (the liver, kidney and heart, etc).
  
  
  CONCLUSIONS
  The pig model of chronic external counterpulsation has been successfully established. Combined use of sodium pentobarbital and 846 mixture is recommended for chronic external counterpulsation.
authors.affiliation: Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510089, China. cxlmce68@yahoo.com.cn
authors.forename: Xiao-lin
authors.initials: XL
authors.lastname: Chen
authors.forename: Xiao-hong
authors.initials: XH
authors.lastname: He
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yue-tao
authors.initials: YT
authors.lastname: Qian
authors.forename: Lu-guang
authors.initials: LG
authors.lastname: Liang
authors.forename: Dian-qiu
authors.initials: DQ
authors.lastname: Fang
authors.forename: Cheng-yang
authors.initials: CY
authors.lastname: Zhan
authors.forename: Zhen-sheng
authors.initials: ZS
authors.lastname: Zheng
authors.forename: Hong
authors.initials: H
authors.lastname: Ma
mesh_terms: D000768:Anesthesia, General / Q000379:methods; D000818:Animals; D000831:Animals, Newborn; D001243:Assisted Circulation; D015908:Counterpulsation / Q000379:methods*; D023421:Models, Animal; D010424:Pentobarbital / Q000008:administration & dosage; D013552:Swine
chemical_list: D010424:Pentobarbital