Development of antibodies to Burkholderia pseudomallei during childhood in melioidosis-endemic northeast Thailand.
A cross-sectional serological survey of 2,214 children living in northeast Thailand was conducted to define the antibody response to Burkholderia pseudomallei from birth to 14 years. There was a sharp rise in detectable antibodies from birth to 4 years followed by reactivity in approximately 60-70% of children thereafter.
Wuthiekanun
Vanaporn
V
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Chierakul
Wirongrong
W
Langa
Sayan
S
Chaowagul
Wipada
W
Panpitpat
Chanathip
C
Saipan
Penchan
P
Thoujaikong
Thaksinaporn
T
Day
Nicholas P
NP
Peacock
Sharon J
SJ
D000293:Adolescent; D000367:Age Factors; D000907:Antibodies, Bacterial / Q000097:blood* / Q000276:immunology; D016957:Burkholderia pseudomallei / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008554:Melioidosis / Q000453:epidemiology / Q000276:immunology*; D015995:Prevalence; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D013785:Thailand / Q000453:epidemiology; D013997:Time Factors
D000907:Antibodies, Bacterial