title: The mid-term effect of bare metal suprarenal fixation on renal function following endovascular abdominal aortic aneurysm repair.
abstract: OBJECTIVE
  The aim of this study was to assess the mid term effect of proximal bare metal fixation design on renal function in patients undergoing endovascular repair (EVR) of abdominal aortic aneurysm (AAA).
  
  
  METHODS
  Consecutive EVR patients for AAA from December 1995-2001 were included and grouped to either infrarenal (Group 1) or uncovered suprarenal (Group 2) fixation. Peri-operative renal function and at 6, 12 and 24 months was determined by serum creatinine (sCr mmol l(-1)) and Cockroft-Gault creatinine clearance (CrC ml min(-1)). Changes in renal function were compared using non-parametric analysis.
  
  
  RESULTS
  Of the 179 EVR procedures during this six-year period, paired renal data was available for 135 patients at a minimal follow-up of 6 months (Gp1, n = 63; Gp2, n = 72). Median pre-EVR sCr and CrC were 113, 57 in Group 1 and 108, 58 in Group 2, p = NS. There was no significant deterioration in renal function within or between either group at 2 years post-EVR: median sCr, CrC values were 118, 56 (Group 1) and 111, 56 (Group 2), all p = NS.
  
  
  CONCLUSIONS
  This study suggests mid-term renal function remains unaffected following EVR of AAA, irrespective of proximal fixation type. Designs to improve stent durability and EVR applicability do not appear to compromise renal function.
authors.affiliation: Northern Vascular Centre, Freeman Hospital, Newcastle upon Tyne, UK.
authors.forename: P
authors.initials: P
authors.lastname: Davey
authors.forename: J D
authors.initials: JD
authors.lastname: Rose
authors.forename: T
authors.initials: T
authors.lastname: Parkinson
authors.forename: M G
authors.initials: MG
authors.lastname: Wyatt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000009:adverse effects*; D017544:Aortic Aneurysm, Abdominal / Q000097:blood / Q000601:surgery* / Q000652:urine; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000209:etiology* / Q000652:urine; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D012077:Renal Artery / Q000601:surgery*; D015607:Stents; D016896:Treatment Outcome
chemical_list: D003404:Creatinine