Integrating microarray gene expression object model and clinical document architecture for cancer genomics research.
Systematic integration of genomic-scale expression profiles with clinical information may facilitate cancer genomics research. MAGE-OM (Microarray Gene Expression Object Model) defines standard objects for genomic but not for clinical data. HL7 CDA (Clinical Document Architecture) is a document model for clinical information, describing syntax (generic structure) but not semantics. We designed a document template in XML Schema with additional constraints for CDA to define content semantics, enabling data model-level integration of MAGE-OM and CDA for cancer genomics research.
Park
Yu Rang
YR
Seoul National University Biomedical Informatics (SNUBI) and Human Genome Research Institute, Seoul National University College of Medicine, Seoul, 110-799, Korea.
Lee
Hye Won
HW
Kim
Ju Han
JH
D020869:Gene Expression Profiling; D023281:Genomics; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D011381:Programming Languages; D012660:Semantics