title: Genital lichen sclerosus in a case of male-to-female gender reassignment.
abstract: Lichen sclerosus (LS) is a chronic cutaneous disorder of uncertain aetiology seen predominantly in females. It is characterized by white atrophic macules and plaques with a predilection for involvement of the genitalia and perianal skin. Gender-identity disorder (transsexualism) is a descriptive term for individuals having the genetic, somatic and hormonal basis of one sex but who identify sexually with the opposite sex. Surgical gender reassignment is a fundamental step in the management of these complex patients and is driven by the individual's belief of being the opposite sex 'trapped' in the wrong body. We report a case of genital lichen sclerosus in hair-bearing skin originally from the scrotum, in an individual who had undergone male-to-female gender reassignment. To our knowledge, no similar cases have been reported to date.
authors.affiliation: Oral Medicine, Division of Maxillofacial Diagnostic, Medical and Surgical Sciences, Eastman Dental Institute for Oral Health Care Sciences, UCL, University of London, and St John's Institute of Dermatology, St Thomas' Hospital, UK. sic@globalnet.co.uk
authors.forename: S I
authors.initials: SI
authors.lastname: Chaudhry
authors.forename: P
authors.initials: P
authors.lastname: Craig
authors.forename: E
authors.initials: E
authors.lastname: Calonje
authors.forename: S M
authors.initials: SM
authors.lastname: Neill
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002990:Clobetasol / Q000627:therapeutic use; D004643:Emollients / Q000627:therapeutic use; D045703:Emulsifying Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D012611:Scrotum / Q000473:pathology; D014189:Transsexualism; D016896:Treatment Outcome; D014845:Vulvar Diseases / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D004643:Emollients; D045703:Emulsifying Agents; D002990:Clobetasol