Influence of gender on outcomes after intra-arterial thrombolysis for acute ischemic stroke.
Recent data suggest that women obtain greater benefit than men from IV fibrinolysis for acute ischemic stroke. It is unknown whether this gender-thrombolysis advantage extends to those treated with intra-arterial (IA) thrombolysis. The authors evaluated the independent effect of gender among ischemic stroke patients treated with IA fibrinolysis and found no differences in short-term clinical and angiographic outcomes between men and women who received IA thrombolysis for acute ischemic stroke.
Shah
S H
SH
Department of Neurology, UCLA Medical Center, USA. SHShah@mednet.ucla.edu
Liebeskind
D S
DS
Saver
J L
JL
Starkman
S
S
Vinuela
F
F
Duckwiler
G
G
Jahan
R
R
Kim
D
D
Sanossian
N
N
Vespa
P
P
Ovbiagele
B
B
D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy* / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000188:drug therapy* / Q000453:epidemiology*; D015912:Thrombolytic Therapy / Q000706:statistics & numerical data*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator