title: Olfactory neuroblastoma in a horse.
abstract: An 11-year-old thoroughbred gelding was euthanatized because of right nasal cavity tumor. The tumor consisted of round to oval cells with a scanty cytoplasm and hyperchromatic nuclei. Homer-Wright rosettes and pseudorosettes, as well as microcysts were seen. Neoplastic cells were immunoreactive to vimentin, S-100 protein, and neuron-specific enolase, glial fibrillary acidic protein and microtube-associated protein in varying degrees, indicating neurogenic nature. Based on these findings, this tumor was diagnosed as an olfactory neuroblastoma. Since this type is an uncommon tumor showing histological variety, the nature is discussed.
authors.affiliation: Department of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
authors.forename: Jyoji
authors.initials: J
authors.lastname: Yamate
authors.forename: Takeshi
authors.initials: T
authors.lastname: Izawa
authors.forename: Keiko
authors.initials: K
authors.lastname: Ogata
authors.forename: Osamu
authors.initials: O
authors.lastname: Kobayashi
authors.forename: Ryoko
authors.initials: R
authors.lastname: Okajima
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kuwamura
authors.forename: Takao
authors.initials: T
authors.lastname: Kotani
authors.forename: Mika
authors.initials: M
authors.lastname: Aoki
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D006734:Horse Diseases / Q000175:diagnosis / Q000473:pathology*; D006736:Horses; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D009296:Nasal Cavity / Q000473:pathology*; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*