title: Healing potential of cream containing extract of Sphaeranthus indicus on dermal wounds in Guinea pigs.
abstract: A cream containing ethanolic extract of aerial parts of Sphaeranthus indicus, Linn. (Asteraceae) was evaluated for wound healing activity in guinea pigs. The cream was applied in vivo on the paravertebral area of six excised wounded models once a day for 15 days. The cream significantly enhanced the rate of wound contraction and the period of epithelialization comparable to neomycin.
authors.affiliation: Dr. HMI Institute of Pharmacology and Herbal Sciences, Hamdard University, Karachi 74600, Pakistan.
authors.forename: Farzana
authors.initials: F
authors.lastname: Sadaf
authors.forename: Rubeena
authors.initials: R
authors.lastname: Saleem
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ahmed
authors.forename: Syed Iqbal
authors.initials: SI
authors.lastname: Ahmad
authors.lastname: Navaid-ul-Zafar
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D006168:Guinea Pigs; D009824:Ointments; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D012867:Skin / Q000293:injuries*; D014945:Wound Healing / Q000187:drug effects*; D014950:Wounds, Penetrating / Q000188:drug therapy*
chemical_list: D009824:Ointments; D010936:Plant Extracts