title: Oxidation in ultrahigh molecular weight polyethylene and cross-linked polyethylene acetabular cups tested against roughened femoral heads in a hip joint simulator.
abstract: This study was aimed at comparing the oxidative degradation of commercial acetabular cups made of cross-linked polyethylene (XLPE) and conventional ultrahigh molecular weight polyethylene (UHMWPE). After testing against deliberately scratched CoCrMo femoral heads in a hip joint simulator, the cups, microtomed parallel to the articulating surface, were analyzed by IR spectroscopy. Due to the potential for artifacts caused by absorbed contaminants, the IR spectra were compared only after hexane extraction; actually, XLPE was found to absorb more serum than UHMWPE. The two sets of unworn acetabular cups showed different oxidation patterns with consequently different distributions of carbonyl species; unworn XLPE was characterized by lower contents of carbonyl species and hydrogen-bonded alcohols and higher contents of trans-vinylene species than unworn UHMWPE. Upon simulator testing, UHMWPE showed more significant changes in oxidation indexes and distribution of carbonyl compounds than XLPE, confirming a better wear behavior for XLPE under the adopted testing conditions.
authors.affiliation: Centro di Studio sulla Spettroscopia Raman, Dipartimento di Biochimica G. Moruzzi, Sezione di Chimica e Propedeutica Biochimica, Via Belmeloro 8/2, Università di Bologna, Bologna, Italy. paola.taddei@unibo.it
authors.forename: Paola
authors.initials: P
authors.lastname: Taddei
authors.forename: Saverio
authors.initials: S
authors.lastname: Affatato
authors.forename: Concezio
authors.initials: C
authors.lastname: Fagnano
authors.forename: Aldo
authors.initials: A
authors.lastname: Toni
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D006622:Hip Prosthesis; D008422:Materials Testing / Q000379:methods; D008970:Molecular Weight; D010084:Oxidation-Reduction; D020959:Polyethylene / Q000737:chemistry*; D011095:Polyethylenes / Q000737:chemistry*; D011474:Prosthesis Design; D011475:Prosthesis Failure
chemical_list: D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D020959:Polyethylene