[Biological therapies of systemic lupus erythematosus].
In recent years new potential therapies of systemic lupus erythematosus, called biological therapies, have been developed. These agents influence some immunological reactions, essential for genesis of systemic lupus erythematosus, ie. T cells and B cells activation, antibodies production, cytokines and complement components activation. Pathogenic basis of using these therapies, their safety and efficacy assessment have been presented.
Olesińska
Marzena
M
Instytut Reumatologii w Warszawie, Klinika Chorób Tkanki Lacznej. olesinska@ir.ids.pl
Chwalińska-Sadowska
Hanna
H
Mielnik
Paweł
P
Wiesik-Szewczyk
Ewa
E
D000936:Antigen-Antibody Complex / Q000378:metabolism; D001688:Biological Products / Q000494:pharmacology* / Q000627:therapeutic use*; D003167:Complement Activation / Q000187:drug effects; D016207:Cytokines / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy / Q000639:trends*; D008180:Lupus Erythematosus, Systemic / Q000276:immunology / Q000628:therapy*; D008213:Lymphocyte Activation / Q000187:drug effects; D015398:Signal Transduction / Q000187:drug effects; D013601:T-Lymphocytes / Q000276:immunology
D000936:Antigen-Antibody Complex; D001688:Biological Products; D016207:Cytokines