title: [A case of pneumonitis suspected to be induced by Oseltamivir].
abstract: A 33-year-old man had a high fever and was given Cefcapene and Oseltamivir without a definite diagnosis of influenza. Three days later an abnormal chest shadow was pointed out. Chest CT revealed ground-glass opacities and air-space consolidation in bilateral lung fields. Although he was given antibiotics, lung infiltrates increased and his symptoms worsened. Therefore, he was transferred to our hospital. Corticosteroid pulse-therapy resulted in prompt improvement of chest infiltrates and his symptoms. The drug-induced lymphocyte stimulating test results indicated 170% of oseltamivir and 150% of cefcapene. Considering the clinical course and laboratory data, this was probably drug-induced lung injury caused by oseltamivir.
authors.affiliation: Department of Respiratory Medicine, National Hospital Organization National Toneyama Hospital.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Namba
authors.forename: Seigo
authors.initials: S
authors.lastname: Kitada
authors.forename: Masahide
authors.initials: M
authors.lastname: Mori
authors.forename: Takeo
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Masaharu
authors.initials: M
authors.lastname: Motone
authors.forename: Manabu
authors.initials: M
authors.lastname: Niinaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Mari
authors.initials: M
authors.lastname: Miki
authors.forename: Keisuke
authors.initials: K
authors.lastname: Miki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Naka
authors.forename: Toru
authors.initials: T
authors.lastname: Hiraga
authors.forename: Ryoji
authors.initials: R
authors.lastname: Maekura
authors.forename: Masami
authors.initials: M
authors.lastname: Ito
mesh_terms: D000081:Acetamides / Q000009:adverse effects*; D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D053139:Oseltamivir; D011014:Pneumonia / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011859:Radiography; D045169:Severe Acute Respiratory Syndrome / Q000175:diagnosis
chemical_list: D000081:Acetamides; D000998:Antiviral Agents; D053139:Oseltamivir