CT appearance of Varicella Zoster lesions in liver and spleen in an immunocompetent patient.
An adult patient presented with vesicular rash and abdominal pain of 5 days duration. His initial laboratory results showed elevated liver enzymes. A contrast enhanced CT scan demonstrated multiple small hypodense nodules in liver and spleen. His serum was reactive for Varicella Zoster IgM. Patient was treated with intravenous Acyclovir for 5 days and followed up with oral tablets for 2 weeks. At 3 weeks, CT scan showed resolution of hypodense nodules and his serum liver enzymes returned to normal at 6 weeks. Patient is on follow up and asymptomatic for 2 years. The CT appearances of nodules and their resolution following specific antiviral therapy are useful in diagnosis and in follow up of disseminated Varicella Zoster.
Venkatesh
Sudhakar Kundapur
SK
Department of Diagnostic Radiology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, Lower Kent Ridge Road, Singapore 119074, Singapore. dnrskv@nus.edu.sg
Lo
Lena Li-Lin
LL
D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002644:Chickenpox / Q000000981:diagnostic imaging* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007121:Immunocompetence; D007902:Length of Stay; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D008297:Male; D013154:Spleen / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000998:Antiviral Agents; D000212:Acyclovir