title: Hypoglycaemic activity of two spices extracts: Rhus coriaria L. and Bunium persicum Boiss.
abstract: The hypoglycaemic efficacy of sumac (Rhus coriaria L.) and black cumin (Bunium persicum Boiss) extracts were investigated through inhibition of a glycoside hydrolase: alpha-amylase. On the basis of our result ethyl acetate extract of sumac may have interest in the treatment and prevention of hyperglycaemia, diabetes and obesity, with an IC50 value of 28.7 microg mL-1.
authors.affiliation: Department of Pharmaceutical Sciences, University of Calabria, I-87036 Rende (CS), Italy.
authors.forename: Statti
authors.initials: S
authors.lastname: Giancarlo
authors.forename: Loizzo Monica
authors.initials: LM
authors.lastname: Rosa
authors.forename: Farsad
authors.initials: F
authors.lastname: Nadjafi
authors.forename: Menichini
authors.initials: M
authors.lastname: Francesco
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D029045:Rhus / Q000737:chemistry*; D000516:alpha-Amylases / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D005419:Flavonoids; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000516:alpha-Amylases