[Polyoma virus BK nephropathy in kidney allograft recipients].
Polyomavirus BK (BKV) infection is a fast growing problem in modern transplantation medicine. Interstitial nephritis is the most important pathology caused by the virus leading to graft failure and the need for dialysis treatment. Ethiopathogenesis of the disease is multifactorial with immunosuppressive treatment playing main role. Many cases of BKV infection have been misdiagnosed and mistreated as steroid-resistant acute rejection. In such cases the infection was spreading what inevitably led to graft failure. Now it is known that the only way to control the disease is close monitoring and decreasing the net state of immunosuppression.
Matłosz
Bartłomiej
B
Klinika Medycyny Transplantacyjnej i Nefrologii, Instytut Transplantologii Akademii Medycznej w Warszawie.
Durlik
Magdalena
M
D001739:BK Virus / Q000302:isolation & purification*; D006084:Graft Rejection / Q000821:virology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007668:Kidney / Q000821:virology; D016030:Kidney Transplantation / Q000009:adverse effects*; D009393:Nephritis / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D027601:Polyomavirus Infections / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D011183:Postoperative Complications / Q000821:virology; D051437:Renal Insufficiency / Q000601:surgery; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000628:therapy / Q000821:virology*
D007166:Immunosuppressive Agents