title: [Secondary lethal catastrophic antiphospholipid syndrome in 24-years old female patient with overlap syndrome (systemic sclerosis and systemic lupus erythematosus)].
abstract: In our article we describe the case of 24 years old woman with overlap syndrome under form of systemic sclerosis and systemic lupus erythematosus complicated by secondary antiphospholipid syndrome (APS). The first manifestation of antiphospholipid syndrome was intrauterine fetal death. Afterwards pulmonary embolism occurred. After several weeks in result of catastrophic course of antiphospholipid syndrome coronary artery thrombosis and myocardial infarction occurred with following prominent left ventricle systolic failure and multi organ failure. The patient died about one month after discharge from the hospital.
authors.affiliation: Akademia Medyczna w Białymstoku, Klinika Reumatologii i Chorób Wewnetrznych.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Ciołkiewicz
authors.forename: Izabela
authors.initials: I
authors.lastname: Domysławska
authors.forename: Karol
authors.initials: K
authors.lastname: Kita
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Muklewicz
authors.forename: Otylia
authors.initials: O
authors.lastname: Kowal-Bielecka
authors.forename: Bogdan
authors.initials: B
authors.lastname: Lewandowski
authors.forename: Stanisław
authors.initials: S
authors.lastname: Sierakowski
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000378:metabolism; D009102:Multiple Organ Failure / Q000175:diagnosis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D017152:Antibodies, Antiphospholipid