title: Epidermotropic metastases from squamous cell carcinoma of the lower female genital tract mimicking primary Bowen's carcinoma.
abstract: Epidermotropic metastases from internal malignancies are exceedingly rare. We report a striking example of epidermotropic metastatic carcinoma of the lower female genital tract to the skin of the abdomen and groin. Atypical cells were scattered throughout the epidermis, mimicking Bowen's disease. Focally, islands of atypical squamous cells were also found in the adjacent dermis. Histopathologically, the lesion resembled a primary invasive squamous cell carcinoma. However, the clinical history of a metastatic carcinoma of the genitalia and the clinical presentation with multiple lesions militated against a primary squamous cell carcinoma and favored interpretation of the lesions as epidermotropic metastases.
authors.affiliation: Department of Pathology, Friedrich-Schiller-University of Jena, Germany.
authors.forename: Anja
authors.initials: A
authors.lastname: Bornkessel
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Weyers
authors.forename: Peter
authors.initials: P
authors.lastname: Elsner
authors.forename: Mirjana
authors.initials: M
authors.lastname: Ziemer
mesh_terms: D001913:Bowen's Disease / Q000473:pathology / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012878:Skin Neoplasms / Q000473:pathology* / Q000556:secondary; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000556:secondary