title: Extent and management of cardiovascular risk factors in patients with type 2 diabetes and serious mental illness.
abstract: Cardiovascular disease is the leading cause of death in Type 2 diabetes, which commonly occurs in patients with serious mental illnesses (SMIs). We determined the extent to which patients with diabetes and SMI, relative to diabetes patients without SMI, met American Diabetes Association goals for cholesterol and blood pressure, met criteria for the metabolic syndrome, and were prescribed medications known to reduce cardiovascular events. We found that less than half of diabetes patients, both with and without SMI, met recommended goals for cholesterol levels; even fewer had adequate blood pressure control. In addition, a substantial proportion of all diabetes patients met metabolic syndrome criteria. However, diabetes patients with SMI were less likely to be prescribed cholesterol-lowering statin medications, angiotensin-converting enzyme inhibitors, and angiotensin receptor blocking agents than diabetes patients without SMI. Patients with both diabetes and SMI are treated less aggressively for high cardiovascular risk than diabetes patients without mental disorders.
authors.affiliation: Division of Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
authors.forename: Julie
authors.initials: J
authors.lastname: Kreyenbuhl
authors.forename: Faith B
authors.initials: FB
authors.lastname: Dickerson
authors.forename: Deborah R
authors.initials: DR
authors.lastname: Medoff
authors.forename: Clayton H
authors.initials: CH
authors.lastname: Brown
authors.forename: Richard W
authors.initials: RW
authors.lastname: Goldberg
authors.forename: Lijuan
authors.initials: L
authors.lastname: Fang
authors.forename: Karen
authors.initials: K
authors.lastname: Wohlheiter
authors.forename: Leena P
authors.initials: LP
authors.lastname: Mittal
authors.forename: Lisa B
authors.initials: LB
authors.lastname: Dixon
mesh_terms: D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D002423:Cause of Death; D002784:Cholesterol / Q000097:blood; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000453:epidemiology; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D024821:Metabolic Syndrome / Q000188:drug therapy* / Q000453:epidemiology; D008875:Middle Aged; D012307:Risk Factors; D012559:Schizophrenia / Q000453:epidemiology
chemical_list: D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002784:Cholesterol