Systemic sclerosis and pseudomesotheliomatous adenocarcinoma of the lung.
A 55-year-old man, diagnosed with systemic sclerosis (SSc) for 20 years, was admitted to our hospital for exertional dyspnea and pleural effusion. Computed tomography scan and cytological findings of the pleural fluid suggested malignant mesothelioma. In the postmortem examination, the tumor was pathologically diagnosed as pseudomesotheliomatous adenocarcinoma (PMA) of the lung, classified into pleomorphic carcinoma with adenocarcinoma component according to the new World Health Organization guidelines. This is the first case report of SSc with PMA.
Yoshimi
Ryusuke
R
Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. yoshiryu@med.yokohama-cu.ac.jp
Takeno
Mitsuhiro
M
Yamanaka
Shoji
S
Shiina
Masaaki
M
Kirino
Yohei
Y
Takeda
Yukiko
Y
Sekiguchi
Akiko
A
Kobayashi
Hiroshi
H
Ihata
Atsushi
A
Motoji
Kyosuke
K
Ohno
Shigeru
S
Ueda
Atsuhisa
A
Soga
Takayoshi
T
Ishigatsubo
Yoshiaki
Y
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008949:Adenoma, Pleomorphic / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D001344:Autopsy; D003584:Cytological Techniques; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis; D008875:Middle Aged; D018301:Neoplasms, Mesothelial / Q000175:diagnosis; D016066:Pleural Effusion, Malignant / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000150:complications*; D014057:Tomography, X-Ray Computed