title: Precursor lesions of adenocarcinoma lung--two case reports.
abstract: Although precursor lesions of bronchogenic squamous cell carcinoma are well documented, the preinvasive lesions of pulmonary adenocarcinoma are seen very rarely. It has been hypothesized that there is a stepwise progression of alveolar epithelial hyperplasia to atypical alveolar hyperplasia and subsequently to malignancy in the pathogenesis of peripheral adenocarcinoma of the lung. In the present paper we would like to share our experience of two cases of pulmonary adenocarcinoma with their precursor lesions in the form of atypical alveolar hyperplasia.
authors.affiliation: Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh.
authors.forename: Deepali
authors.initials: D
authors.lastname: Jain
authors.forename: K
authors.initials: K
authors.lastname: Joshi
authors.forename: S K
authors.initials: SK
authors.lastname: Jindal
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*; D011650:Pulmonary Alveoli / Q000473:pathology*