title: Age-related changes in calretinin-immunoreactive periglomerular cells in the rat main olfactory bulb.
abstract: The changes of calretinin (CR)-immunoreactive periglomerular cells in the glomerular layer of the main olfactory bulb (MOB) were investigated in rats differing ages from postnatal month 1 (PM 1) to PM 24. The number of cresyl violet-positive periglomerular cells was similar between PM 1 and PM 12, but they decreased slightly in the PM 24 group. The size of CR-immunoreactive periglomerular cells in the glomerular layer increased with age, while their numbers did not change significantly in the PM 6-PM 24 groups. In the PM 24 group, numbers of CR-positive periglomerular cell bodies and their processes decreased, while the size of CR-positive cell bodies in the glomeruli was larger than that of the previous groups. These results suggest that CR-immunoreactive periglomerular cells in the rat MOB are well-developed in the PM 6 group, and that periglomerular cells in the PM 24 group show poor CR-immunoreactivity compared to those in the PM 6 group.
authors.affiliation: Department of Anatomy, College of Medicine, Hallym University, Chunchon, South Korea.
authors.forename: In Koo
authors.initials: IK
authors.lastname: Hwang
authors.forename: Ki-Yeon
authors.initials: KY
authors.lastname: Yoo
authors.forename: Young Sam
authors.initials: YS
authors.lastname: Nam
authors.forename: Jung Hoon
authors.initials: JH
authors.lastname: Choi
authors.forename: Kangmoon
authors.initials: K
authors.lastname: Seo
authors.forename: In Se
authors.initials: IS
authors.lastname: Lee
authors.forename: Ju Young
authors.initials: JY
authors.lastname: Jung
authors.forename: Tae-Cheon
authors.initials: TC
authors.lastname: Kang
authors.forename: Yang-Seok
authors.initials: YS
authors.lastname: Oh
authors.forename: Moo Ho
authors.initials: MH
authors.lastname: Won
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D064032:Calbindin 2; D007150:Immunohistochemistry; D008297:Male; D009830:Olfactory Bulb / Q000033:anatomy & histology / Q000166:cytology* / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*
chemical_list: C576512:Calb2 protein, rat; D064032:Calbindin 2; D064030:S100 Calcium Binding Protein G