title: Secondary transmission of varicella vaccine virus in a chronic care facility for children.
abstract: A 16-year-old varicella-seronegative resident at a chronic care facility received varicella vaccine; 15 days later he developed severe varicella. Subsequently, a 13-year-old resident and a 39-year-old health care worker developed mild varicella. We demonstrate that vaccine-strain virus was transmitted to both persons, and that transmission included at least 2 variant vaccine strains.
authors.affiliation: Hattie Larlham Center for Children With Disabilities, Mantua, Ohio, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Grossberg
authors.forename: Rafael
authors.initials: R
authors.lastname: Harpaz
authors.forename: Elena
authors.initials: E
authors.lastname: Rubtcova
authors.forename: Vladimir
authors.initials: V
authors.lastname: Loparev
authors.forename: Jane F
authors.initials: JF
authors.lastname: Seward
authors.forename: D Scott
authors.initials: DS
authors.lastname: Schmid
mesh_terms: D000293:Adolescent; D000328:Adult; D002644:Chickenpox / Q000235:genetics / Q000635:transmission*; D019433:Chickenpox Vaccine / Q000009:adverse effects* / Q000276:immunology; D002648:Child; D003428:Cross Infection / Q000635:transmission* / Q000821:virology; D005260:Female; D006801:Humans; D007121:Immunocompetence; D017758:Infectious Disease Transmission, Patient-to-Professional; D008297:Male; D017354:Point Mutation; D012112:Residential Facilities
chemical_list: D019433:Chickenpox Vaccine