title: Stent-graft treatment of infected aortic and arterial aneurysms.
abstract: OBJECTIVE
  To evaluate the feasibility and effectiveness of endovascular stent-graft repair of infected aortic and arterial aneurysms.
  
  
  METHODS
  Eight patients (5 men; mean age 56.6 years, range 30-85) with infected saccular aneurysms in the brachiocephalic artery (n=1), proximal descending thoracic aorta (n=1), infrarenal abdominal aorta (n=3), common iliac artery (n=1), and common femoral artery (n=2) were treated with stent-graft placement and intravenous antibiotic treatment for at least 6 weeks followed by case-specific administration of oral suppressive antibiotics. All patients were considered to be in the high-surgical-risk group.
  
  
  RESULTS
  Exclusion of the infected aneurysm was successful in all patients. However, 2 patients died within 30 days of uncontrolled sepsis, and 1 patient died at 6 months after rupture of a persistently infected aneurysm (37% mortality rate). Over a follow-up that ranged to 8 years, the 5 survivors showed complete resolution of the infected aneurysms; no stent-graft infection was observed during follow-up.
  
  
  CONCLUSIONS
  The acceptable technical and clinical success of endovascular aneurysm repair makes this a promising treatment for infected aortic and arterial aneurysms. However, it is crucial that the infection is treated adequately prior to stent-graft placement.
authors.affiliation: Department of Radiology and Research Institute of Radiological Science, Seoul, Republic of Korea.
authors.forename: Kwang-Hun
authors.initials: KH
authors.lastname: Lee
authors.forename: Jong Yun
authors.initials: JY
authors.lastname: Won
authors.forename: Do Yun
authors.initials: DY
authors.lastname: Lee
authors.forename: Donghoon
authors.initials: D
authors.lastname: Choi
authors.forename: Won-Heum
authors.initials: WH
authors.lastname: Shim
authors.forename: Byung Chul
authors.initials: BC
authors.lastname: Chang
authors.forename: Sang Joon
authors.initials: SJ
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000785:Aneurysm, Infected / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D017130:Angioplasty; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D017544:Aortic Aneurysm, Abdominal / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017543:Iliac Aneurysm / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents