title: Can venlafaxine in breast milk attenuate the norepinephrine and serotonin reuptake neonatal withdrawal syndrome.
abstract: A newborn infant whose mother had used venlafaxine, a selective inhibitor of both norepinephrine and serotonin reuptake, throughout pregnancy exhibited signs consistent with the norepinephrine and serotonin reuptake withdrawal syndrome. Is it possible that mother's milk can help mitigate the effects of norepinephrine and serotonin reuptake withdrawal? Pharmacokinetic analysis and review of the only published case with active treatment of a baby with venlafaxine suggest that breastfeeding may mitigate the neonatal withdrawal syndrome.
authors.affiliation: The Motherisk Program, Hospital for Sick Children, Toronto ON.
authors.forename: Gideon
authors.initials: G
authors.lastname: Koren
authors.affiliation: The Motherisk Program, Hospital for Sick Children, Toronto ON.
authors.forename: Myla
authors.initials: M
authors.lastname: Moretti
authors.affiliation: The Motherisk Program, Hospital for Sick Children, Toronto ON.
authors.forename: Bhushan
authors.initials: B
authors.lastname: Kapur
mesh_terms: D001942:Breast Feeding; D003511:Cyclohexanols / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D011247:Pregnancy; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D000069470:Venlafaxine Hydrochloride
chemical_list: D003511:Cyclohexanols; D017367:Selective Serotonin Reuptake Inhibitors; D000069470:Venlafaxine Hydrochloride