[An analysis for genetic polymorphism of twelve Y short tandem repeat loci in Chaoshan populations].
OBJECTIVE
To study the genetic polymorphism of twelve short tandem repeat loci of Y chromosome in Chaoshan Han populations.


METHODS
Twelve Y short tandem repeat loci, of which the template DNAs were extracted from blood samples of 121 unrelated Chaoshan Han individuals, were amplified by using the PowerPlex Y system. The PCR products were genotyped with ABI PRISM 3100 genetic analyzer.


RESULTS
From the loci DYS19, DYS437, DYS389I, DYS389II, DYS438, DYS439, DYS393, DYS391, DYS390, and DYS392, 4-7 alleles were checked out; from the loci DYS385, 35 alleles were observed. The overall observed haplotype diversity reached 0.9976. DYS391 was the locus with the lowest gene diversity (0.4445), while DYS385 had the highest gene diversity (0.9525).


CONCLUSIONS
The 12 Y-STR loci are highly polymorphic and suitable to forensic casework, population genetics and anthropology studies.
Liu
Jing-wen
JW
Center for Molecular Biology, Medical College, Shantou University, Shantou, Guangdong, 515031 PR China.
Hu
Sheng-ping
SP
Li
Biao
B
D002681:China; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D005838:Genotype; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*