title: Radiological-pathological correlation in lipoblastoma and lipoblastomatosis.
abstract: BACKGROUND
  Lipoblastoma and lipoblastomatosis are uncommon benign mesenchymal lesions that predominantly occur in infancy and early childhood.
  
  
  OBJECTIVE
  To evaluate the imaging and histological features of lipoblastoma and lipoblastomatosis.
  
  
  METHODS
  Retrospective review of the radiological and pathological findings in children with lipoblastoma and lipoblastomatosis treated at a single centre between 1997 and 2004.
  
  
  RESULTS
  Eight children (median age 18 months) had undergone imaging and surgery at our institution. An infiltrative growth pattern was identified at imaging in two children with lipoblastomatosis, and a well-defined mass in six children with lipoblastoma. In all patients, imaging showed a lesion composed mostly, but not entirely, of fat. There were no recurrences at follow-up of between 1 and 91 months.
  
  
  CONCLUSIONS
  In infancy and early childhood, the identification of a tumour composed mostly of fat should suggest the diagnosis of lipoblastoma or lipoblastomatosis.
authors.affiliation: Department of Radiology, Great Ormond Street Hospital, London, WC1N 3JH, UK.
authors.forename: Shruti
authors.initials: S
authors.lastname: Moholkar
authors.forename: Neil J
authors.initials: NJ
authors.lastname: Sebire
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Roebuck
mesh_terms: D001132:Arm / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000175:diagnosis* / Q000473:pathology; D008068:Lipomatosis / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008482:Mediastinum / Q000473:pathology; D009852:Omentum / Q000000981:diagnostic imaging / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013131:Spine / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography