title: Application of continuous positive airway pressure in hypoxemic acute respiratory failure associated with diastolic dysfunction in pregnancy.
abstract: Diastolic heart failure with hypoxemia is a dangerous condition in pregnancy for both the mother and the fetus. Continuous positive airway pressure may help to decrease afterload and reduce venous return and ventricular filling, but its use in diastolic dysfunction has not yet been established. The authors report a case of a patient with pregnancy-induced hypertension and oligohydramnios who developed acute decompensated diastolic heart failure. The addition of continuous positive airway pressure, diuretics, and neurohormonal-blocking agents lead to a dramatic clinical and physiologic improvement. The authors recommend consideration of the use of positive pressure ventilation in these patients.
authors.affiliation: Department of Pulmonary & Critical Care Medicine, Hackensack University Medical Center, Hackensack, NJ 07601, USA.
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Hutter
authors.forename: Robert
authors.initials: R
authors.lastname: Berkowitz
authors.forename: S Edward
authors.initials: SE
authors.lastname: Davis
authors.forename: Hormoz
authors.initials: H
authors.lastname: Ashtyani
mesh_terms: D000208:Acute Disease; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D045422:Continuous Positive Airway Pressure; D003971:Diastole / Q000187:drug effects; D004232:Diuretics / Q000627:therapeutic use; D000077545:Eplerenone; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy*; D008790:Metoprolol / Q000627:therapeutic use; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy*; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D013148:Spironolactone / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D004232:Diuretics; D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D000077545:Eplerenone; D005665:Furosemide; D008790:Metoprolol