Steroidal alkaloids from bulbs of Fritillaria lichuanensis.
A new steroidal alkaloid, hupehenizioiside (1), together with four known steroidal alkaloids hupehenizine (2), hupehenirine (3), peiminine (4) and hupeheninoside (5), were isolated and identified from the bulbs of Fritillaria lichuanensis. The structure of hupehenizioiside (1) was determined to be (20R,25S)-5alpha,14alpha,17beta-cevanine-6-oxo-3beta-O-beta-D-glucoside by spectral analysis and chemical evidence. Compounds (2)-(5) were isolated from Fritillaria lichuanensis for the first time.
Pi
Hui-Fang
HF
Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
Ruan
Han-Li
HL
Zhang
Yong-Hui
YH
Niu
Lei-Ming
LM
Wu
Ji-Zhou
JZ
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D002595:Cevanes / Q000737:chemistry; D031410:Fritillaria; D005960:Glucosides / Q000737:chemistry; D015394:Molecular Structure; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification*
D000470:Alkaloids; D002595:Cevanes; D005960:Glucosides; D013256:Steroids; C511966:hupehenirine; C511967:hupehenizine; C511965:hupehenizioiside; C047384:hupeheninoside; C047331:peiminine