Helicobacter pylori infection and its correlation to extraesophageal and esophageal reflux in contact granuloma patients.
To evaluate the presence of Helicobacter pylori (H. pylori) infection and its correlation to extraesophageal and esophageal reflux, 18 consecutive contact granuloma patients were examined by laryngoscopy, 24-hour double probe pH monitoring and [13C]-urea breath test. Sixteen of the 18 patients (89%) were H. pylori-negative, while 2 patients (11%) showed positive test results. Extraesophageal reflux was detected in 14 patients; one of them was H. pylori-positive. In the ten patients with abnormal distal esophageal reflux, one was H. pylori-positive. The present results do not confirm increased prevalence for H. pylori infection in contact granuloma patients and the occurrence of H. pylori infection was not correlated to the amount of pharyngeal or esophageal acid exposure.
Ylitalo
Riitta
R
Department of Otolaryngology, Karolinska University Hospital Huddinge, Stockholm, and Department of Clinical Sciences - Otolaryngology, University of Umeå, Umeå, Sweden. riitta.h.ylitalo@klinvet.ki.se
D000328:Adult; D000368:Aged; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000382:microbiology; D005931:Glottis; D006099:Granuloma / Q000150:complications*; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification* / Q000472:pathogenicity; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications*; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis