title: Acute tonsillopharyngitis associated with atypical bacterial infection in children: natural history and impact of macrolide therapy.
abstract: This study evaluated the natural history of acute tonsillopharyngitis associated with atypical bacterial infections, showing that Mycoplasma pneumoniae and Chlamydia pneumoniae organisms are frequently found in children with acute tonsillopharyngitis. The study also demonstrated, for what we believe to be the first time, that, unless adequately treated, acute tonsillopharyngitis associated with infection with M. pneumoniae and C. pneumoniae may have a negative outcome with a high risk of recurrence of respiratory illness.
authors.affiliation: Institute of Pediatrics, University of Milan, Milano, Italy.
authors.forename: Susanna
authors.initials: S
authors.lastname: Esposito
authors.forename: Samantha
authors.initials: S
authors.lastname: Bosis
authors.forename: Enrica
authors.initials: E
authors.lastname: Begliatti
authors.forename: Roberta
authors.initials: R
authors.lastname: Droghetti
authors.forename: Elena
authors.initials: E
authors.lastname: Tremolati
authors.forename: Claudia
authors.initials: C
authors.lastname: Tagliabue
authors.forename: Marta
authors.initials: M
authors.lastname: Bellasio
authors.forename: Francesco
authors.initials: F
authors.lastname: Blasi
authors.forename: Nicola
authors.initials: N
authors.lastname: Principi
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial; D017963:Azithromycin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D023521:Chlamydophila Infections / Q000188:drug therapy*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009175:Mycoplasma Infections / Q000188:drug therapy*; D009177:Mycoplasma pneumoniae / Q000276:immunology*; D010608:Pharyngeal Diseases / Q000188:drug therapy* / Q000382:microbiology*; D010612:Pharyngitis / Q000188:drug therapy / Q000382:microbiology; D012008:Recurrence; D014069:Tonsillitis / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017963:Azithromycin