Uterine adenosarcoma detected by Papanicolaou smear: a case report.
Adenosarcoma is a rare uterine biphasic tumor composed of benign epithelial elements and a sarcomatous stroma. Although it is well described histologically, its cytological features are rarely mentioned in the literature. We describe a case of uterine adenosarcoma that was first detected by Papanicolau (Pap) smear. Numerous crowded clusters of spindle cells were present within a bloody background, as well as a few smaller, dyscohesive groups with cells showing high N:C ratio and oval to round nuclei with coarse chromatin and small nucleoli. A few nuclear grooves were identified. Adenosarcomas are rare lesions but should be considered in the differential diagnosis when spindled cells are noted in a pap smear.
Pasternak
Sylvia
S
Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
MacIntosh
Rebecca
R
D018195:Adenosarcoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006801:Humans; D065006:Papanicolaou Test; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery; D014626:Vaginal Smears