title: Treatment of pseudomyxoma peritonei with two times--cytoreduction and hypertermic antiblastic peritoneal perfusion (HAPP).
abstract: Pseudomyxoma peritonei is a rare neoplasia with a low grade of clinical malignity in which neoplastic masses product large amount of mucinous material. Its treatment advocates an aggressive cytoreduction of all visceral and peritoneal lesions and Hyperthermic Antiblastic Peritoneal Perfusion (HAPP). In three cases we programmed a two stage surgical approach for the massive amount of peritoneal implants. Two times we achieved our aim, while one time, the wide progression of the disease during the two surgical procedures made useless our efforts to have a complete cytoreduction and the following HAPP. This last patient refused systemic chemotherapy between the two surgeries and we think that this should be one of the reasons of the failure.
authors.affiliation: San Giuseppe Hospital, Oncological Surgery Department, Empoli. m.desimone@usl11.tos.it
authors.forename: M
authors.initials: M
authors.lastname: De Simone
authors.forename: S
authors.initials: S
authors.lastname: Scuderi
authors.forename: M
authors.initials: M
authors.lastname: Vaira
authors.forename: D
authors.initials: D
authors.lastname: Costamagna
authors.forename: R
authors.initials: R
authors.lastname: Barone
authors.forename: G
authors.initials: G
authors.lastname: Fiorentini
authors.forename: P
authors.initials: P
authors.lastname: Dentico
authors.forename: A
authors.initials: A
authors.lastname: Caponi
authors.forename: B
authors.initials: B
authors.lastname: Ciaccio
authors.forename: C
authors.initials: C
authors.lastname: Caponi
authors.forename: L
authors.initials: L
authors.lastname: Ferri
authors.forename: E
authors.initials: E
authors.lastname: Martini
authors.forename: S
authors.initials: S
authors.lastname: Cantini
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods; D003131:Combined Modality Therapy; D013505:Digestive System Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000628:therapy*; D011553:Pseudomyxoma Peritonei / Q000628:therapy*