title: Thromboprophylaxis in microsurgery.
abstract: Microsurgical free tissue transfer has become a gold standard in a wide range of clinical situations. Thrombosis at the anastomotic site is not only the most common cause of failure of microsurgical operations, but it is also one of the factors resulting in microcirculatory intravascular thrombosis in free flaps. All conditions of thrombus formation, defined by Virchow in 1856, are encountered in free flap surgery. This literature review concerns the problem of thromboprophylaxis in microsurgery. All citations published this last ten years (1996-2005) concerning this problem are noted. Data are confronted with other specialties, particularly vascular surgery, or with large retrospective studies. Protocol used in our institution is presented at the end of this lecture.
authors.affiliation: Dpts of Anesthesia and Intensive Care Medicine, University Hospital Sart Tilman, University of Liège, Liège, Belgium. jplecoq@chu.ulg.ac.be
authors.forename: J P
authors.initials: JP
authors.lastname: Lecoq
authors.forename: M
authors.initials: M
authors.lastname: Senard
authors.forename: G M
authors.initials: GM
authors.lastname: Hartstein
authors.forename: M
authors.initials: M
authors.lastname: Lamy
authors.forename: O
authors.initials: O
authors.lastname: Heymans
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D000818:Animals; D006801:Humans; D008833:Microcirculation; D008866:Microsurgery / Q000009:adverse effects / Q000379:methods*; D013524:Surgical Flaps; D013927:Thrombosis / Q000517:prevention & control*; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000379:methods*