Using routine laboratory tests to detect heavy drinking in the general population.
This article describes a new biomarker known as the Early Detection of Alcohol Consumption (EDAC) test, which has been steadily penetrating the U.S. market. The EDAC uses routine laboratory tests to make a prediction of heavy drinking in any given person. When tested in mainstream insurance populations, the EDAC has shown twice the specificity of the traditional liver enzyme tests and is significantly more sensitive than the CDT test, which is expected because the EDAC uses a combination of laboratory tests. Maximum diagnostic accuracy is achieved when the CDT test is used to confirm a positive EDAC test. Since brief interventions have proven successful, the early identification of alcohol problems becomes a vital role for physicians. Improved awareness of alcohol misuse can certainly be accomplished through an increased use of biomarkers, with and without concomitant self-report. The ultimate goal is to facilitate early intervention and the successful management of patients diagnosed with heavy drinking.
Harasymiw
Jim
J
Alcohol Detection Services, Big Bend, WI 53103, USA. edac@execpc.com
Seaberg
Julie
J
Bean
Pamela
P
D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000097:blood* / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood; D003955:Diagnostic Tests, Routine; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D011159:Population Surveillance; D014168:Transferrin / Q000031:analogs & derivatives* / Q000032:analysis; D014481:United States
D015415:Biomarkers; D014168:Transferrin; C056759:carbohydrate-deficient transferrin