title: Role of vocal cord function and dysfunction in patients presenting with symptoms of acute asthma exacerbation.
abstract: A total of 48 patients presenting to the emergency department as acute asthma exacerbation were prospectively studied. Rhinolaryngoscopy was conducted with simultaneous flow measurements and spirometry performed before and after the procedure. Measurements of the vocal cord opening during various phases of respiration were analyzed. Only 4 of 48 patients had anterior two-thirds closure of the vocal cords with a diamond-shaped opening posteriorly during expiration. One additional patient had inspiratory and expiratory closure of the vocal cords. The previously unreported high incidence of anterior two-thirds closure (10.4%) of the vocal cords suggests that the upper airway has a role to play in a significant number of patients presenting with symptoms of asthma exacerbation.
authors.affiliation: Pulmonary Critical Care & Sleep Medicine, University of Louisville Health Sciences Center, Kentucky, USA. subin.jain@gmail.com
authors.forename: Subin
authors.initials: S
authors.lastname: Jain
authors.forename: Venkata
authors.initials: V
authors.lastname: Bandi
authors.forename: Todd
authors.initials: T
authors.lastname: Officer
authors.forename: Marie
authors.initials: M
authors.lastname: Wolley
authors.forename: Kalpalatha K
authors.initials: KK
authors.lastname: Guntupalli
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D005260:Female; D005931:Glottis / Q000503:physiopathology; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012129:Respiratory Function Tests; D013147:Spirometry; D014827:Vocal Cords / Q000503:physiopathology*