title: [18FDG PET cerebral function imaging in 10 vascular dementia patients receiving needling at Baihui(DU20), Shuigou(DU26) and Shenmen(HT7)].
abstract: OBJECTIVE
  To observe the effect of needling at Baihui(DU20), Shuigou(DU26) and Shenmen(HT7) on glucose metabolism in different regions of the brain in vascular dementia patients.
  
  
  METHODS
  Ten patients with vascular dementia were randomized into 2 groups, and the patients in the control group received the treatment with needling in the routine acupoints for hemiplegia (chosen from 6 Yang meridians of the hand and foot), while those in treatment group received needling at 3 additional acupoints, namely Baihui(DU20), Shuigou(DU26) and Shenmen(HT7), which were specific for dementia treatment. All the patients were examined by positron-emission tomography(PET) to detect the glucose metabolism in different brain regions before and after acupuncture treatment by means of semiquantitative analysis of the average values of radioactive count in the brain regions.
  
  
  RESULTS
  Needling at the additional 3 acupoints could obviously enhance glucose metabolism in the bilateral frontal lobes, bilateral thalamus, temporal lobe and lentiform nucleus on the uncompromised side.
  
  
  CONCLUSIONS
  The effect of needling at Baihui(DU20), Shuigou(DU26) and Shenmen(HT7) on vascular dementia is closely related to improved cerebral glucose metabolism.
authors.affiliation: Department of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. liuchengjing@126.com
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Sheng-xu
authors.initials: SX
authors.lastname: Wang
authors.forename: Qiu-shi
authors.initials: QS
authors.lastname: Li
authors.forename: Yong-jiu
authors.initials: YJ
authors.lastname: Liang
authors.forename: Yong-ning
authors.initials: YN
authors.lastname: Guo
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000368:Aged; D001921:Brain / Q000378:metabolism; D015140:Dementia, Vascular / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D005947:Glucose