Liver disease and osteoporosis.
Metabolic bone disease (osteodystrophy) is an important complication of patients with chronic liver disease; its etiology is complex and multifactorial. Osteodystrophy is manifested as osteopenia/osteoporosis. Osteoporosis can predispose patients to bone fractures, increasing morbidity and mortality, especially after liver transplantation. Early evaluation, screening, and treatment of bone disorders in patients with liver disease are essential to minimize fracture risk and to improve clinical outcome and quality of life.
Sanchez
Antonio J
AJ
Division of Gastroenterology, Hepatology, and Liver Transplantation, Mayo Clinic Foundation, Jacksonville, FL, USA.
Aranda-Michel
Jaime
J
D001205:Ascorbic Acid / Q000378:metabolism / Q000627:therapeutic use; D001851:Bone Diseases, Metabolic / Q000209:etiology* / Q000517:prevention & control* / Q000628:therapy; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D008107:Liver Diseases / Q000150:complications* / Q000378:metabolism; D044623:Nutrition Therapy; D010024:Osteoporosis / Q000209:etiology / Q000517:prevention & control; D014807:Vitamin D / Q000378:metabolism / Q000627:therapeutic use; D014812:Vitamin K / Q000378:metabolism / Q000627:therapeutic use
D014812:Vitamin K; D014807:Vitamin D; D001205:Ascorbic Acid; D002118:Calcium