title: Advances in vaccine stability monitoring technology.
abstract: Electronic time-temperature indicator (eTTI) monitors can be programmed to exactly follow the stability characteristics of vaccines with a high degree of realism. The monitors have a visual output, enabling vaccine status to be assessed at a glance, and can also output more detailed statistical data. When packaged with vaccine vials in groups of about 10 vials per box, the eTTI can remain with a vaccine throughout most of the vaccine's lifetime. The monitors can detect essentially all cold-chain breaks, and can detect issues, such as inadvertent freezing, that are presently not detected by other vaccine stability monitors such as Vaccine Vial Monitors (VVM).
authors.affiliation: CliniSense Corporation, 109-355 Los Gatos, CA 95032, USA. szweig@clinisense.com
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Zweig
mesh_terms: D004355:Drug Stability; D004356:Drug Storage; D005615:Freezing; D017325:Hepatitis B Vaccines / Q000592:standards; D011055:Poliovirus Vaccine, Oral / Q000592:standards; D013696:Temperature; D014612:Vaccines / Q000592:standards*
chemical_list: D017325:Hepatitis B Vaccines; D011055:Poliovirus Vaccine, Oral; D014612:Vaccines