Asymmetric Michael addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) zinc complexes.
The first asymmetric synthesis of 1,3-dinitro compounds through Michael addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric chiral tridentate bis(oxazoline) and bis(thiazoline) zinc complexes was achieved with high enantioselectivities (up to 95% ee).
Lu
Shao-Feng
SF
Beijing National Laboratory for Molecular Sciences, Peking University, Beijing 100871, China.
Du
Da-Ming
DM
Xu
Jiaxi
J
Zhang
Shi-Wei
SW
D000473:Alkanes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D008956:Models, Chemical; D009574:Nitro Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D000473:Alkanes; D000475:Alkenes; D009574:Nitro Compounds; D009942:Organometallic Compounds; D010080:Oxazoles; D013844:Thiazoles; D002244:Carbon; D015032:Zinc