title: Fingerprinting DHFR in single-molecule AFM studies.
authors.affiliation: Biological Sciences Columbia University New York, New York 10027, USA.
authors.forename: Sri Rama Koti
authors.initials: SR
authors.lastname: Ainavarapu
authors.forename: Lewyn
authors.initials: L
authors.lastname: Li
authors.forename: Julio M
authors.initials: JM
authors.lastname: Fernandez
mesh_terms: D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D016466:CHO Cells; D002846:Chromatography, Affinity; D006224:Cricetinae; D003412:Cricetulus; D005492:Folic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D005493:Folic Acid Antagonists / Q000494:pharmacology; D006801:Humans; D008024:Ligands; D008727:Methotrexate / Q000494:pharmacology; D018625:Microscopy, Atomic Force / Q000379:methods*; D009243:NAD / Q000737:chemistry; D009249:NADP / Q000737:chemistry; D009536:Niacinamide / Q000737:chemistry; D010449:Peptide Mapping / Q000379:methods*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation; D011489:Protein Denaturation; D015202:Protein Engineering; D017510:Protein Folding; D021381:Protein Transport; D013053:Spectrophotometry; D013314:Stress, Mechanical; D013718:Tensile Strength; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D005493:Folic Acid Antagonists; D008024:Ligands; D009243:NAD; D009536:Niacinamide; C010920:dihydrofolate; D009249:NADP; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D046988:Proteasome Endopeptidase Complex; D008727:Methotrexate