Kazusa mammalian cDNA resources: towards functional characterization of KIAA gene products.
The Kazusa cDNA project pioneered an extensive sequencing project of human cDNAs in their entirety and focused sequencing efforts particularly on large cDNAs encoding large proteins. More than 2000 human genes, referred to as 'KIAA' genes, were initially identified through this cDNA project. Since many KIAA genes still remain functionally uncharacterized, our current focus is to determine their biological functions in vivo. In this review, we describe the current status of the Kazusa mammalian cDNA resources and the future direction of the functional characterization of KIAA genes.
Nagase
Takahiro
T
Department of Human Gene Research, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu, Chiba 292-0818, Japan.
Koga
Hisashi
H
Ohara
Osamu
O
D000818:Animals; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000032:analysis*; D030541:Databases, Genetic; D030562:Databases, Protein; D005544:Forecasting; D006801:Humans; D007564:Japan; D051379:Mice; D016366:Open Reading Frames; D011994:Recombinant Proteins / Q000096:biosynthesis
D018076:DNA, Complementary; D011994:Recombinant Proteins