The sympathetic control of blood pressure.
Hypertension - the chronic elevation of blood pressure - is a major human health problem. In most cases, the root cause of the disease remains unknown, but there is mounting evidence that many forms of hypertension are initiated and maintained by an elevated sympathetic tone. This review examines how the sympathetic tone to cardiovascular organs is generated, and discusses how elevated sympathetic tone can contribute to hypertension.
Guyenet
Patrice G
PG
Department of Pharmacology, Health Sciences Center, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908-0735, USA. pgg@virginia.edu
D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D002490:Central Nervous System / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000473:pathology / Q000503:physiopathology; D007031:Hypothalamus / Q000502:physiology; D008526:Medulla Oblongata / Q000502:physiology; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology*