title: Switch-peptides to trigger the peptide guided assembly of poly(ethylene oxide)-peptide conjugates into tape structures.
abstract: A strong beta-sheet forming peptide was conjugated to PEO and utilized to guide the structure formation process toward well-defined, tape-like structures with millimeters in length, about 2 mum width, and approximately 50 nm height. The aggregation tendency of the peptide was temporarily suppressed for ease of synthesis by the integration of multiple switch-peptide defect segments into the peptide backbone. A subsequent rearrangement in the defects re-establishes the native peptide backbone and triggers the assembly by switching the aggregation properties on.
authors.affiliation: Max Planck Institute of Colloids and Interfaces, MPI KGF Golm, 14424 Potsdam, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Hentschel
authors.forename: Eberhard
authors.initials: E
authors.lastname: Krause
authors.forename: Hans G
authors.initials: HG
authors.lastname: Börner
mesh_terms: D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D010455:Peptides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D010455:Peptides; D011092:Polyethylene Glycols