title: [Interaction of Staphylococcus aureus alpha-toxin with eukaryotic cells and their target].
abstract: In this review information on S. aureus alpha-toxin is expounded. The data on the targets of the action of the toxin on eukaryotic cells, its activity with respect to different membrane structures, effects established in the interaction of toxin and cell elements, as well as of its biological action on the macroorganism, are presented. Information on the factors inactivating the cytolytic action of the toxin is given.
authors.forename: A F
authors.initials: AF
authors.lastname: Khaziev
authors.forename: N A
authors.initials: NA
authors.lastname: Mikhaĭlova
authors.forename: L P
authors.initials: LP
authors.lastname: Blinkova
mesh_terms: D000818:Animals; D001419:Bacteria / Q000378:metabolism*; D001427:Bacterial Toxins / Q000037:antagonists & inhibitors / Q000276:immunology / Q000378:metabolism*; D002122:Calcium Chloride / Q000494:pharmacology; D002462:Cell Membrane / Q000378:metabolism; D003165:Complement System Proteins / Q000494:pharmacology; D003603:Cytotoxins / Q000037:antagonists & inhibitors / Q000378:metabolism; D005057:Eukaryotic Cells / Q000378:metabolism* / Q000473:pathology; D006460:Hemolysin Proteins; D007106:Immune Sera / Q000494:pharmacology; D007477:Ions / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology; D011485:Protein Binding; D012964:Sodium / Q000494:pharmacology; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D003603:Cytotoxins; D006460:Hemolysin Proteins; D007106:Immune Sera; D007477:Ions; C021091:staphylococcal alpha-toxin; D003165:Complement System Proteins; D012964:Sodium; D002122:Calcium Chloride; D011188:Potassium