title: Studies of cocaine- and amphetamine-regulated transcript (CART) knockout mice.
abstract: CART (cocaine- and amphetamine-regulated transcript) peptides are neuropeptides expressed throughout the central nervous system and have been implicated in a variety of physiological processes. Research on the many physiological processes involving CART peptide have been somewhat limited by the lack of an identified CART antagonist. Development of CART peptide deficient mice has allowed scientists to further explore the many functions of CART peptide. This review briefly summarizes recent findings in the literature characterizing CART peptide deficient mice.
authors.affiliation: Division of Neuroscience, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA. mcmoffe@emory.edu
authors.forename: Mark
authors.initials: M
authors.lastname: Moffett
authors.forename: Lisa
authors.initials: L
authors.lastname: Stanek
authors.forename: Jill
authors.initials: J
authors.lastname: Harley
authors.forename: George
authors.initials: G
authors.lastname: Rogge
authors.forename: Mark
authors.initials: M
authors.lastname: Asnicar
authors.forename: Hansen
authors.initials: H
authors.lastname: Hsiung
authors.forename: Michael
authors.initials: M
authors.lastname: Kuhar
mesh_terms: D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D001835:Body Weight / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000494:pharmacology; D003042:Cocaine / Q000494:pharmacology; D051379:Mice; D018345:Mice, Knockout; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein
chemical_list: D000697:Central Nervous System Stimulants; D009419:Nerve Tissue Proteins; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein; D000661:Amphetamine; D003042:Cocaine