title: Papillary glioneuronal tumor radiologically mimicking a cavernous hemangioma with hemorrhagic onset.
abstract: Papillary glioneuronal tumor is a recently identified low-grade brain neoplasm classified as variant of ganglioglioma. Its salient morphological characteristics are the presence of pseudopapillary structures composed of blood vessels, often hyalinized, lined by uniform small astrocytes and a proliferation of neurocytic cells, eventually admixed with ganglioid and ganglion cells. We present a case of papillary glioneuronal tumor occurring in a 15-year-old female with an unusual hemorrhagic onset. The clinical, morphological and immunohistochemical features are discussed and the published literature is reviewed. This article proposes that papillary glioneuronal tumor should be included in the differential diagnosis of patients with tumoral related brain hemorrhage.
authors.affiliation: Department of Human Pathology and Oncology, University of Florence, Florence, Italy. ambuccoliero@unifi.it
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Buccoliero
authors.forename: Flavio
authors.initials: F
authors.lastname: Giordano
authors.forename: Federico
authors.initials: F
authors.lastname: Mussa
authors.forename: Antonio
authors.initials: A
authors.lastname: Taddei
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Genitori
authors.forename: Gian Luigi
authors.initials: GL
authors.lastname: Taddei
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D018303:Ganglioglioma / Q000150:complications / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D020786:Hemangioma, Cavernous, Central Nervous System / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D025321:Surgery, Computer-Assisted; D014057:Tomography, X-Ray Computed