Management of endometrial cancer.
OBJECTIVE
To review broadly the diagnosis and treatment of endometrial cancer, concentrating on the evidence base.


METHODS
The peer reviewed literature has been cited selectively to support the principal themes of the review.


RESULTS
A rising incidence of endometrial cancer will continue to present challenges to improve survival particularly for high-risk and advanced disease. Lymphadenectomy and adjuvant radiotherapy are and will be used more rationally as evidence for their effectiveness accumulates.


CONCLUSIONS
The area of greatest need in endometrial cancer is now to improve outcomes for women with advanced/recurrent disease.
Kitchener
H
H
Academic Unit of Obstetrics & Gynaecology, University of Manchester, St Mary's Hospital, Whitworth Park, Manchester ARK, United Kingdom. henry.kitchener@cmmc.nhs.uk <henry.kitchener@cmmc.nhs.uk>
D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008197:Lymph Node Excision; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome