Pseudo-Bartter syndrome in a pregnant mother and her fetus.
Pseudo-Bartter syndrome presents the same clinical and biological characteristics as Bartter syndrome but without primary renal tubule abnormalities. We relate the case of a premature baby presenting at birth with severe hypokalemic metabolic alkalosis associated with hyponatremia and hypochloremia. Maternal blood at the time of delivery showed the same electrolyte perturbations. The baby's mother had suffered from anorexia and vomiting during pregnancy. A few weeks after birth the baby's blood abnormalities had almost returned to normal. Chloride depletion is at the origin of both maternal and fetal hypokalemic alkalosis.
Mathot
Mikael
M
CHC St Vincent Neonatology Unit, Rocourt, Belgium.
Maton
Pierre
P
Henrion
Elisabeth
E
François-Adant
Anne
A
Marguglio
Arnaud
A
Gaillez
Stéphanie
S
Collard
Laure
L
Langhendries
Jean-Paul
JP
D000328:Adult; D000471:Alkalosis / Q000175:diagnosis / Q000235:genetics; D001477:Bartter Syndrome / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D005333:Fetus / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007008:Hypokalemia / Q000175:diagnosis / Q000235:genetics; D007231:Infant, Newborn; D009035:Mothers; D011247:Pregnancy; D049992:Sodium Chloride Symporters / Q000378:metabolism; D014883:Water-Electrolyte Imbalance
D049992:Sodium Chloride Symporters