Fatal myocardial necrosis caused by Staphylococcus lugdunensis and cytomegalovirus in a patient with scleroderma.
A 42-year-old woman developed a rapidly progressing fatal heart failure. At the autopsy extensive necrosis of the myocardium was seen, with an almost complete absence of inflammatory cells and the presence of bacterial structures identified as Staphylococcus lugdunensis by PCR. In addition, the cytomegalovirus genome was found to be located inside the cardiomyocytes.
Pirilä
Laura
L
Department of Medicine, University of Turku, Turku, Finland.
Söderström
Karl-Ove
KO
Hietarinta
Marja
M
Jalava
Jari
J
Kytö
Ville
V
Toivanen
Auli
A
D000328:Adult; D017675:CREST Syndrome / Q000150:complications*; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D032342:Muscle Cells / Q000382:microbiology / Q000821:virology; D009205:Myocarditis / Q000382:microbiology* / Q000821:virology*; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D013203:Staphylococcal Infections / Q000382:microbiology; D013210:Staphylococcus / Q000302:isolation & purification*