title: Scrub typhus: chest radiographic and clinical findings in 130 Thai patients.
abstract: OBJECTIVE
  To describe chest radiographic findings and their clinical correlation in patients with scrub typhus diagnosed in Thailand and to determine abnormalities that assist in the diagnosis of scrub typhus.
  
  
  METHODS
  Between July 2001 and December 2002, 130 patients with scrub typhus admitted to three hospitals in the northeastern Thailand were studied. Data of clinical presentations and chest radiographic findings, reviewed by two radiologists who were unaware of the final diagnosis, were analyzed.
  
  
  RESULTS
  There were 33 women, 97 men; age range, 11-92 years; median age, 45 years old. Pulmonary symptoms occurred in 61.5% of the patients and eschar was found in 33.1%. Hepatic dysfunction occurred in 58.5% and cardiovascular dysfunction in 33%. Pulmonary involvement was the major presentation in 41.5%. Acute respiratory distress syndrome developed in 7 patients. Overall 5 patients died. The initial radiography showed abnormalities in 64.6% of the patients. Common radiographic abnormalities included bilateral reticular opacities (48.5%), cardiomegaly (28.5%), congestive heart failure (18.5%), air space nodules (13.1%), and pleural effusion (10.8%). Significant association between chest radiographic abnormalities and hepatic and cardiovascular dysfunction were documented.
  
  
  CONCLUSIONS
  Chest radiography should be included in the initial evaluation of patients with suspected scrub typhus. Bilateral reticular infiltration, with or without cardiomegaly or congestive heart failure, was the most frequent radiographic finding of scrub typhus.
authors.affiliation: Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. ch_aphinya@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Charoensak
authors.forename: O
authors.initials: O
authors.lastname: Chawalparit
authors.forename: C
authors.initials: C
authors.lastname: Suttinont
authors.forename: K
authors.initials: K
authors.lastname: Niwattayakul
authors.forename: K
authors.initials: K
authors.lastname: Losuwanaluk
authors.forename: S
authors.initials: S
authors.lastname: Silpasakorn
authors.forename: Y
authors.initials: Y
authors.lastname: Suputtamongkol
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006332:Cardiomegaly / Q000175:diagnosis / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013902:Radiography, Thoracic; D012612:Scrub Typhus / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D013785:Thailand