title: Identification of bovine viral diarrhea virus type 2 in Korean native goat (Capra hircus).
abstract: In the genus Pestivirus, four genetically distinct viral species are currently recognized: bovine viral diarrhea viruses type 1 and 2 (BVDV-1, BVDV-2), classical swine fever virus (CSFV) and border disease virus (BDV). BVDV-1 and BDV infections have been described in goat species. Since 1998, border disease (BD) like symptoms in goats have been reported repeatedly in two southern-most provinces of Korea, which until then had been regarded as being free from BD. As a result of retrospective investigations of BD-like syndrome in goat reported between 1998 and 2004, a pestivirus was identified from intestinal content of an affected kid submitted in 1999. Both sequences of 5'-non-coding region and complete N(pro) gene from the isolate were analyzed to identify the genotype. Interestingly, the results revealed that the isolate belonged to BVDV-2 that is rarely reported even in cattle. The isolate showed close relationship to North American and European strains rather than the geographically closer Japanese strains. To authors' knowledge, this is the first identification of BVDV-2 in goat species.
authors.affiliation: National Veterinary Research and Quarantine Services, 480, Anyang6-dong, Gyonggi-do 430-824, Republic of Korea.
authors.forename: In-Joong
authors.initials: IJ
authors.lastname: Kim
authors.forename: Bang-Hun
authors.initials: BH
authors.lastname: Hyun
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Shin
authors.forename: Kyoung-Ki
authors.initials: KK
authors.lastname: Lee
authors.forename: Kyung-Woo
authors.initials: KW
authors.lastname: Lee
authors.forename: Kyoung-Oh
authors.initials: KO
authors.lastname: Cho
authors.forename: Mun-Il
authors.initials: MI
authors.lastname: Kang
mesh_terms: D020121:5' Untranslated Regions; D000818:Animals; D000829:Animals, Domestic / Q000821:virology*; D000833:Animals, Suckling / Q000821:virology; D030242:Diarrhea Virus 2, Bovine Viral / Q000145:classification*; D005814:Genes, Viral; D015511:Goat Diseases / Q000821:virology*; D006041:Goats / Q000821:virology*; D007422:Intestines / Q000821:virology; D007723:Korea; D008969:Molecular Sequence Data; D018182:Pestivirus Infections / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D012189:Retrospective Studies; D013045:Species Specificity
chemical_list: D020121:5' Untranslated Regions