title: Getting a DNA to do an RNA's job.
abstract: The successful in vitro evolution of a DNA enzyme based on a ribozyme could offer insights into early evolutionary events and provide guidelines for designing hardier catalytic oligonucleotides.
authors.forename: Michael
authors.initials: M
authors.lastname: Eisenstein
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D019143:Evolution, Molecular; D009154:Mutation; D000069497:Origin of Life; D016337:RNA, Catalytic / Q000737:chemistry* / Q000235:genetics*
chemical_list: D016337:RNA, Catalytic; D004247:DNA