title: Paradoxical deterioration during the course of antituberculous treatment.
abstract: Paradoxical deterioration during antituberculous therapy is defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. Although it has frequently been reported for patients infected with human immunodeficiency virus (HIV), it can also be seen in HIV-negative patients. Here, we present a case of miliary tuberculosis in a patient who clinically deteriorates after antituberculous treatment, and discuss this confusing entity under the light of the pertinent literature.
authors.affiliation: Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey. karalonal@yahoo.com
authors.forename: Ibrahim Koral
authors.initials: IK
authors.lastname: Onal
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Bayraktar
authors.forename: Serhat
authors.initials: S
authors.lastname: Unal
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018450:Disease Progression; D006801:Humans; D008297:Male; D017211:Treatment Failure; D014391:Tuberculosis, Miliary / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents