MR and MRCP in the evaluation of primary sclerosing cholangitis: current applications and imaging findings.
Primary sclerosing cholangitis is a progressive cholestatic disease of unknown etiology leading to cirrhosis and liver failure. Several imaging modalities have been used to study this disease, including ultrasonography, computed tomography and hepatobiliary scintigraphy, but accurate diagnosis was found to be best made with endoscopic retrograde cholangiopancreatography or direct cholangiography. However, these 2 methods are invasive and may produce serious complications. Magnetic resonance cholangiopancreatography is a noninvasive imaging technique that has become very useful for diagnosing primary sclerosing cholangitis. Contrast enhanced magnetic resonance imaging provides pertinent information of extraductal abnormalities in addition to biliary ductal changes.
Elsayes
Khaled M
KM
Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA, and Department of Radiology, Theodore Bilhars Institute, Giza, Egypt. elsayesk@mir.wustl.edu
Oliveira
Erica P
EP
Narra
Vamsidhar R
VR
Abou El Abbass
Hatem A
HA
Ahmed
Moustafa I
MI
Tongdee
Ranista
R
Brown
Jeffrey J
JJ
D000328:Adult; D001650:Bile Duct Neoplasms / Q000175:diagnosis; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000175:diagnosis; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation; D008206:Lymphatic Diseases / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged