title: The o-xylylene protecting group as an element of conformational control of remote stereochemistry in the synthesis of spiroketals.
abstract: Protection of trans-1,2-diol segments as cyclic o-xylylene ethers strongly favours diequatorial over diaxial dispositions; the possibility of using this grouping for remote control of the stereochemistry in the synthesis of spiroketals is here demonstrated by the stereoselective synthesis of tricyclic spirodisaccharides (di-D-fructose dianhydrides).
authors.affiliation: Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Apartado 553, E-41071, Sevilla, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: Balbuena
authors.forename: Enrique M
authors.initials: EM
authors.lastname: Rubio
authors.forename: Carmen
authors.initials: C
authors.lastname: Ortiz Mellet
authors.forename: José M
authors.initials: JM
authors.lastname: García Fernández