title: Sclerosing stromal tumour of the ovary--a clinicopathologic spectrum.
abstract: Majority of the Sclerosing stromal tumours of the ovary documented in the literature are single case reports. We report a series of 4 cases. Among the 4 cases encountered the mean age at presentation was 22.2 years. The clinical presentation varied from asymptomatic mass per abdomen (2 cases), menorrhagia (1 case) and amenorrhoea (1 case). The tumour was unilateral in all the cases with an average size of 10 cms. Grossly the appearances varied from a solid, partly cystic, edematous tumour (2 cases) to solid,firm tumour with yellow flecks (1 case) to unilocular cystic tumour (1 case). Microscopically, the tumour was characterized by cellular pseudolobules composed of a disorderly admixture of collagen-producing fibroblasts and lipid rich lutein cells with shrunken nuclei. In one case the lutein cells had a robust appearance with abundant cytoplasm and vesicular nuclei. The pseudolobules were very vascular and separated by hypocellular dense to oedematous fibrous tissue. Frozen section demonstrated fat in luteinized cells in 3 cases.
authors.affiliation: Department of Pathology, Kasturba Medical College, Mangalore, Karnataka.
authors.forename: Radha Ramachandra
authors.initials: RR
authors.lastname: Pai
authors.forename: Sameer Singh
authors.initials: SS
authors.lastname: Shaktawat
authors.forename: Urmila Niranjan
authors.initials: UN
authors.lastname: Khadilkar
authors.forename: Flora Dorothy
authors.initials: FD
authors.lastname: Lobo
authors.forename: Vatsala Srinivas
authors.initials: VS
authors.lastname: Rao
authors.forename: Reba
authors.initials: R
authors.lastname: Philipose
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D010053:Ovary / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*