Novel recombinant norovirus causing outbreaks of gastroenteritis in Santiago, Chile.
Capsid and polymerase (RdRp) genes of 13 norovirus outbreak strains from Chile were compared. The genes sequences were discordant for five strains, and recombination was confirmed for two of them by amplification of a 1,360-bp gene segment containing a fragment of both genes. These strains belonged to a novel genogroup by RdRp sequence and to genogroup GII/3 by capsid sequence. Determining the clinical and epidemiological impact of human calicivirus recombination will require future studies.
Vidal
Roberto
R
Programa de Microbiología, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Roessler
Patricia
P
Solari
Verónica
V
Vollaire
Jimena
J
Jiang
Xi
X
Matson
David O
DO
Mamani
Nora
N
Prado
Valeria
V
O'Ryan
Miguel L
ML
D001483:Base Sequence; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000821:virology; D002213:Capsid; D036022:Capsid Proteins / Q000235:genetics; D002677:Chile / Q000453:epidemiology; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D004196:Disease Outbreaks; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008969:Molecular Sequence Data; D029322:Norovirus / Q000235:genetics*; D010802:Phylogeny; D011995:Recombination, Genetic
D036022:Capsid Proteins; D012321:DNA-Directed RNA Polymerases