Central sensitisation in visceral pain disorders.
The concepts of visceral hyperalgesia and visceral hypersensitivity have been examined in a variety of functional gastrointestinal disorders (FGIDs). Although the pathophysiological mechanisms of pain and hypersensitivity in these disorders are still not well understood, exciting new developments in research have been made in the study of the brain-gut interactions involved in the FGIDs.
Moshiree
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B
Department of Medicine, University of Florida College of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, 1600 SW Archer Rd, HD 602, PO Box 100214, Gainesville, FL 32610-0214, USA.
Zhou
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Q
Price
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DD
Verne
G N
GN
D001921:Brain / Q000503:physiopathology*; D017615:Enteric Nervous System / Q000503:physiopathology*; D005767:Gastrointestinal Diseases / Q000503:physiopathology*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000503:physiopathology; D009619:Nociceptors / Q000502:physiology; D010146:Pain / Q000503:physiopathology*; D017288:Pain Threshold; D017833:Visceral Afferents / Q000502:physiology