Pentacyclic triterpenoids from leaves of Excoecaria agallocha.
A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2-6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3beta-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1-6 were found inactive in vitro against several human cancer cell lines.
Zou
Jian-Hua
JH
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Beijing 100050, PR China.
Dai
Jungui
J
Chen
Xiaoguang
X
Yuan
Jing-Quan
JQ
D018938:Caco-2 Cells; D019665:Euphorbiaceae / Q000737:chemistry*; D006801:Humans; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D053978:Pentacyclic Triterpenes / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*
D053978:Pentacyclic Triterpenes; C413246:oleanane; D009828:Oleanolic Acid