Comparison of acrylic and polymethyl methacrylate lenses in a pediatric population.
OBJECTIVE
To compare the intra-patient incidence of posterior capsular opacification (PCO) and their post operative course, in children with bilateral cataract, following implantation of acrylic (Group 1) and polymethyl methacrylate (PMMA) (Group 2) intraocular lenses (IOLs).


METHODS
This was a prospective, interventional intra-patient case series. Twenty-five children with bilateral cataract, 5 years and older, underwent cataract surgery and implantation of an acrylic (AcrySof MA30BA, Alcon, Fortworth, TX) in one eye and PMMA (Indo Am IAB 203, Ocular Vision, Inc.) IOL in the other eye of each patient. They were followed up for an average of 11.1 +/- 9.5 months to assess the incidence of clinically significant PCO and occurrence of postoperative complications.


RESULTS
Twenty-three children (46 eyes), were included in this study. Post-operatively, 22(95.6%) patients with acrylic IOLs and 20 (86.9%) patients with PMMA IOLs, either maintained or improved their vision. In the acrylic and PMMA IOL groups respectively, the incidence of clinically significant PCO was 21% (4) and 75% (12) ( P =0.002), with a median onset at 2.9 months and 0.7 months. Other complications included pupillary capture in 2 (8.7%) eyes and uveal prolapse in 1 (4.3%) eye in the acrylic group and increased uveal inflammation in 6 (26.1%) eyes and presumed noninfectious endophthalmitis in 2 (8.7%) eyes in the PMMA group.


CONCLUSIONS
Incidence of PCO and post operative uveal inflammation is significantly less with acrylic lenses and were safe to use in pediatric eyes.
Aasuri
Murali K
MK
Cornea Service, LV Prasad Eye Institute, Hyderabad, India.
Fernandes
Merle
M
Pathan
Padmaja Preetam
PP
D000180:Acrylic Resins; D002386:Cataract / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007903:Lens Capsule, Crystalline / Q000473:pathology; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D011446:Prospective Studies; D011474:Prosthesis Design
D000180:Acrylic Resins; D019904:Polymethyl Methacrylate