title: Anterior segment ischaemia with giant cell arteritis.
abstract: METHODS
  A 69-year-old male presented with bilateral blurred vision, left periocular pain, and headache. Ocular examination revealed a right optic neuropathy and left anterior segment ischaemia. An elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) raised suspicion of giant cell arteritis (GCA), which was confirmed by temporal artery biopsy. Treatment with intravenous methylprednisolone followed by a gradually reducing dose of oral prednisolone improved vision in both eyes.
  
  
  CONCLUSIONS
  GCA typically affects large- and medium-sized vessels. It is a recognised cause of anterior ischaemic optic neuropathy. Anterior segment ischaemia is usually caused by disease of the anterior ciliary arteries not typically affected by GCA. This case illustrates that GCA can rarely cause anterior segment ischaemia, without posterior segment involvement in the same eye.
authors.affiliation: Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK. b_mckillop@hotmail.com
authors.forename: Elisabeth
authors.initials: E
authors.lastname: McKillop
authors.forename: Deepak
authors.initials: D
authors.lastname: Tejwani
authors.forename: Cliff
authors.initials: C
authors.lastname: Weir
authors.forename: Jeffery
authors.initials: J
authors.lastname: Jay
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment / Q000098:blood supply*; D001706:Biopsy; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D004359:Drug Therapy, Combination; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D013699:Temporal Arteries / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D002097:C-Reactive Protein; D011239:Prednisolone; D008775:Methylprednisolone