Unnoticed spread of class 1 integrons in gram-positive clinical strains isolated in Guangzhou, China.
A total of 46 gram-positive bacteria isolated from clinical specimens collected in China were subjected to PCR analysis with the intI1-specific primers, and the intI1-positive strains were further analyzed for their resistance gene cassette. All isolates possessed the class 1 integron in their genomes and the array of gene cassettes was dhfrXII-orfF-aadA2, which is very similar to other organisms except in one isolate carrying an additional copy of the class 1 integron containing the aadA2 gene cassette. Altogether, the results indicate that the class 1 integron is widespread in gram-positive clinical strains isolated in Guangzhou, China.
Shi
Lei
L
College of Food and Biological Engineering, South China University of Technology.
Zheng
Meiping
M
Xiao
Zenghuang
Z
Asakura
Masahiro
M
Su
Jianyu
J
Li
Lin
L
Yamasaki
Shinji
S
D024881:Drug Resistance, Bacterial / Q000235:genetics; D022761:Gene Transfer, Horizontal; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D032023:Integrons; D008826:Microbial Sensitivity Tests