title: [Inhibitory effect of Panax notoginseng on the VSMC proliferation induced by hyperlipidemia serum].
abstract: OBJECTIVE
  To investigate the effect of P. notoginseng on vascular smooth muscle cell (VSMC) proliferation induced by hyperlipidemia serum.
  
  
  METHODS
  MTT method was used to investigate the effect of hyperlipidemia serum and hyperlipidemia plus P. notoginseng on VSMC proliferation.
  
  
  RESULTS
  Hyperlipidemia serum could promote VSMC proliferation significantly as compared with the control group (P < 0.05), while hyperlipidemia plus P. notoginseng could weaken this effect significantly (P < 0.05).
  
  
  CONCLUSIONS
  P. notoginseng can significantly inhibit the VSMC proliferation induced by hyperlipidemia serum.
authors.affiliation: Changhai Hospital, Second Military Medicine University, Shanghai 200433, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Jin-Hong
authors.initials: JH
authors.lastname: Hu
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000166:cytology; D049109:Cell Proliferation / Q000187:drug effects*; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D006949:Hyperlipidemias / Q000097:blood*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000166:cytology; D032389:Myocytes, Smooth Muscle / Q000166:cytology; D053723:Panax notoginseng / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D044967:Serum
chemical_list: D004365:Drugs, Chinese Herbal