One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent.
A mild and highly efficient one pot-one step condensation and/or condensation-cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2, 2-dimethyl-1-propanol resulted with excellent yields.
Kangani
Cyrous O
CO
Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Kelley
David E
DE