[Microarray data analysis].
Microarrays might be used for future diagnostic and prognostic purposes. High-density oligonucleotide arrays are promising in this respect. The microarray data consist of intensity files, which are transformed into expression matrices by the application of several mathematical modifications. However, pitfalls regarding data analysis seem to be a critical factor for the impact of this new technology. This article focuses on the data analysis, from raw data file to marker gene lists used to retrieve knowledge about underlying biological processes.
Borup
Rehannah H A
RH
RH Microarray Center, H:S Rigshospitalet, Klinisk Biokemisk afdeling, København. rborup@rh.dk/rehannah@email.dk
Csillag
Claudio
C
Nielsen
Ole Haagen
OH
Nielsen
Finn Cilius
FC
D020869:Gene Expression Profiling / Q000379:methods; D006801:Humans; D046228:Microarray Analysis / Q000379:methods*; D009369:Neoplasms / Q000145:classification / Q000175:diagnosis / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D011379:Prognosis