title: Database predictors of transfusion and mortality.
abstract: Transfusion is a cornerstone of early trauma care, but little is known regarding the consistency of transfusion practice in different regions of the world. We examined data available in the German Trauma Registry, the University of Miami Trauma Registry, and the Registry of the Shock Trauma Center in Baltimore to learn more regarding this question. We sought to identify the rate of transfusion of trauma patients during the resuscitative phase, the volume of transfusion administered, and the correlation of various levels of transfusion with clinical outcomes such as mortality, hospital length of stay, and the incidence of organ system failure. Mortality associated with transfusion was remarkably similar in all three systems, making it clear that the volume of blood received during early resuscitation is a strong predictor of outcome for patients presenting in hemorrhagic shock.
authors.affiliation: R Adams Cowley Shock Trauma Center, University of Medicine Medical System, 22 South Greene St., Baltimore MD 21201, USA. rdutton@umaryland.edu
authors.forename: Richard P
authors.initials: RP
authors.lastname: Dutton
authors.forename: Rolf
authors.initials: R
authors.lastname: Lefering
authors.forename: Mauricio
authors.initials: M
authors.lastname: Lynn
mesh_terms: D000328:Adult; D015142:Baltimore; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D005260:Female; D005431:Florida; D005858:Germany; D006801:Humans; D015601:Injury Severity Score; D007902:Length of Stay; D008297:Male; D012042:Registries; D012307:Risk Factors; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000401:mortality* / Q000628:therapy*