Analysis of retinal findings of acute retinal necrosis using optical coherence tomography.
OBJECTIVE
To analyze the retinal findings in patients with ARN, optical coherence tomography (OCT) was performed.


METHODS
Seven patients (7 eyes) with ARN were studied using OCT.


RESULTS
OCT images depicted highly reflective areas in the inner layers of the retina in all seven cases, corresponding with the yellowish-white lesions of the retina in the acute phase. Disorganization of the retinal structure was also observed in these retinal lesions, especially in cases with severe inflammation. Subretinal changes including retinal exudate and/or fluid were observed in only one case. After regression of the yellowish-white lesions in the retina, a significant reduction in retinal thickness was observed on OCT.


CONCLUSIONS
OCT permits the detection of full-thickness retinal necrosis in the acute phase and complete absence of retinal structure in the resolution phase, corresponding with the yellowish-white lesions seen in patients with ARN.
Suzuki
Jun
J
Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan. jun-s@qc4.so-net.ne.jp
Goto
Hiroshi
H
Minoda
Hiroshi
H
Iwasaki
Takuya
T
Sakai
J
J
Usui
Masahiko
M
D000328:Adult; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence