[Selected aspects of the epidemiological analysis of celiac disease and diabetes mellitus type 1 coexistance in children and youth].
Modern serological tests and changed clinical appearance are the causes of more frequent occurrence of celiac disease (CD) in general population, also in risk groups for instance in patients suffering from diabetes mellitus type 1 (DM t. 1). The aim of the study was to estimate the frequency of CD in patients with DM t. 1 and attempt at evaluation of some factors making to incidence.


METHODS
It was examined 446 patients (titre of anty-endomysial antibodies (anty EMA), endoscopic biopsy in these with titre > 1OIF). The frequency of CD elevated 5.16%, it was sex and duration of DM t. 1 independent. Children with confirmed CD were younger and earlier suffered from DM t. 1 in comparison with these negative anty EMA.


RESULTS
Higher frequency of CD in younger children, who suffered from DM t. 1 to the completion of the fourth year was shown. It wasn't stated the relationship between duration of DM t. 1 and frequency of CD.


CONCLUSIONS
This study indicates the necessity to perform serological studies of CD in diabetic patients. Annual screening tests of CD in first fourth years of DM t. 1 in children before the completion of the fourth year of life seem to be justified.
Zbikowska-Bojko
Magdalena
M
Collegium Medicum Uniwersytetu im. Mikołaja Kopernika w Toruniu, Szpital Uniwersytecki w Bydgoszczy, Klinika Pediatrii, Alergologii i Gastroenterologii.
Szaflarska-Popławska
Anna
A
Pilecki
Olgierd
O
Charemska
Dorota
D
Iwaniszewska
Barbara
B
Nowak
Irena
I
Czerwionka-Szaflarska
Mieczysława
M
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001323:Autoantibodies / Q000097:blood*; D002446:Celiac Disease / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011044:Poland / Q000453:epidemiology; D015995:Prevalence
D001323:Autoantibodies