title: Relationship of epileptic discharges to arousal instability and periodic leg movements in a case of nocturnal frontal lobe epilepsy: a stereo-EEG study.
abstract: We describe the case of a patient with nocturnal frontal lobe epilepsy, presenting with periodic leg movements during sleep and complaining of excessive daytime sleepiness. With the support of intracerebral electroencephalogram recordings and the corroboration of the postoperative outcome, periodic leg movements during sleep and excessive daytime sleepiness appeared to be associated to enhanced arousal instability induced by by recurrent epileptic discharges not detectable on scalp electroencephalogram.
authors.affiliation: Epilepsy Surgery Centre C. Munari, Centre of Sleep Medicine, Niguarda Hospital, Milan, Italy. lino.nobili@ospedaleniguarda.it
authors.forename: Lino
authors.initials: L
authors.lastname: Nobili
authors.forename: Ivana
authors.initials: I
authors.lastname: Sartori
authors.forename: Michele
authors.initials: M
authors.lastname: Terzaghi
authors.forename: Francione
authors.initials: F
authors.lastname: Stefano
authors.forename: Roberto
authors.initials: R
authors.lastname: Mai
authors.forename: Laura
authors.initials: L
authors.lastname: Tassi
authors.forename: Liborio
authors.initials: L
authors.lastname: Parrino
authors.forename: Massimo
authors.initials: M
authors.lastname: Cossu
authors.forename: Giorgio
authors.initials: G
authors.lastname: Lo Russo
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology*; D001921:Brain / Q000473:pathology; D004569:Electroencephalography / Q000295:instrumentation*; D017034:Epilepsy, Frontal Lobe / Q000150:complications* / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D020189:Nocturnal Myoclonus Syndrome / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D017286:Polysomnography; D011300:Preoperative Care; D012720:Severity of Illness Index; D012895:Sleep, REM / Q000502:physiology