title: [Relationship of changes in radius bone mineral density during seven years in working women around thirty years old with lifestyle, body measurement data and laboratory data].
abstract: OBJECTIVE
  A longitudinal study was conducted to investigate the relationships of the change in radius bone mineral density for seven years with lifestyle, body measurement data and laboratory data.
  
  
  METHODS
  The subjects of this study were 191 female employees working in an LSI manufacturing factory in Japan. Bone mineral density was measured on the radius of their nondominant side using DXA (dual energy X-ray absorptiometry) in 1995 and 2002. Other medical examinations were performed at the same time. Multiple regression analysis was also performed with the change in radius bone mineral density as the dependent variable.
  
  
  RESULTS
  As a result of the multiple regression analysis, a significant positive correlation was observed between the change in body mass index (BMI) and the change in bone mineral density among the subjects aged 30 years and over and those under 30 years. A significant positive correlation was observed between daily milk intake and the change in bone mineral density among those aged under 30 years. A significant negative correlation was observed between daily alcohol intake and the change in bone mineral density among those aged under 30 years, and also between parity and the change in bone mineral density among those aged 30 years and over.
  
  
  CONCLUSIONS
  BMI, parity, daily milk intake and daily alcohol intake are considered as significant factors that contribute to a change in bone mineral density. It is necessary that the recommended timing for medical examination be set according to age, and that a well-balanced guidance be provided from young adulthood.
authors.affiliation: Division of Public Health, Department of Social Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Komiya
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakao
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Kuroda
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Arizono
authors.forename: Ai
authors.initials: A
authors.lastname: Nakahara
authors.forename: Mari
authors.initials: M
authors.lastname: Miyauchi
authors.forename: Takahiko
authors.initials: T
authors.lastname: Katoh
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects; D015992:Body Mass Index; D015519:Bone Density; D004032:Diet; D004365:Drugs, Chinese Herbal; D028001:Eleutherococcus; D005260:Female; D006801:Humans; D007564:Japan; D008019:Life Style; D011884:Radius / Q000378:metabolism*; D012044:Regression Analysis; D013997:Time Factors; D014931:Women, Working
chemical_list: D004365:Drugs, Chinese Herbal; C400150:Acanthopanax gracilistylus, extract