title: [Beneficial effects of antimalarials in the treatment of generalized granuloma annular in children].
abstract: Granulma annulare is a polymorphic granulomatous disease of the skin. It has a chronic course and affects mainly children and young adults. We report two cases of generalized granuloma annulare in children successfully treated with antimalarials. Two children, 6 and 12 years of age, without clinical history, presented with multiple granuloma annulare lesions which did not respond to potent topical steroids. Blood glucose level was normal. These lesions responded to small doses of antimalarials. No side effects were noticed. Compared with other drugs, with potential important side effects for children. Small doses of antimalarials might be beneficial in the treatment of generalized granuloma annulare.
authors.affiliation: Service de Dermatologie, EPS Hédi Chaker de Sfax, Tunisie.
authors.forename: Abderrahman
authors.initials: A
authors.lastname: Masmoudi
authors.forename: Wafa
authors.initials: W
authors.lastname: Abdelmaksoud
authors.forename: Hamida
authors.initials: H
authors.lastname: Turki
authors.forename: Mongia
authors.initials: M
authors.lastname: Hachicha
authors.forename: Salaheddin
authors.initials: S
authors.lastname: Marrekchi
authors.forename: Madiha
authors.initials: M
authors.lastname: Mseddi
authors.forename: Samir
authors.initials: S
authors.lastname: Bouassida
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Zahaf
mesh_terms: D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D002738:Chloroquine / Q000627:therapeutic use; D005260:Female; D016460:Granuloma Annulare / Q000188:drug therapy*; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008297:Male
chemical_list: D000962:Antimalarials; D006886:Hydroxychloroquine; D002738:Chloroquine