Myasthenia gravis accompanied with hypokalemic periodic paralysis.
Myasthenia gravis and hypokalemic periodic paralysis are commonly related with hyperthyroidism but rarely occur together. Here, the authors reported a case of hypokalemic periodic paralysis in a Northeastern Thai woman accompanied with myasthenia gravis. She had motor weakness despite a normal level of serum potassium. Prostigmine test was positive. She dramatically improved after pyridostigmine treatment. Autoantibodies to nicotinic AchR-Ab and dihydropyridine receptor or L-type voltage gated calcium channel were postulated to explain these associated diseases.
Sawanyawisuth
K
K
Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
Tiamkao
S
S
Pratipanawatr
T
T
D000328:Adult; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000503:physiopathology*; D009157:Myasthenia Gravis / Q000188:drug therapy* / Q000503:physiopathology*; D011729:Pyridostigmine Bromide / Q000627:therapeutic use*; D013785:Thailand
D002800:Cholinesterase Inhibitors; D011729:Pyridostigmine Bromide