title: Diffraction enhanced imaging of controlled defects within bone, including bone-metal gaps.
abstract: Gap regions between a bone and an implant, whether existing upon insertion or developing over time, can lead to implant failure. Currently, planar x-ray imaging and CT are the most commonly used methods to evaluate the gap region. An alternative to these available clinical imaging modalities could help to better evaluate bone resorption. Previous experiments with diffraction enhanced imaging (DEI) have shown significant contrast advantages over monochromatic synchrotron radiation (SR) imaging. DEI and planar SR radiography images of bone samples with drill holes and gap regions of known geometry were acquired at the NSLS beamline X15A (Upton, NY, USA). The images acquired with DEI show measurable contrast-to-noise gains when compared to the images acquired using SR radiography.
authors.affiliation: Brookhaven National Lab, Upton, NY 11973, USA. connord@bnl.gov
authors.forename: D M
authors.initials: DM
authors.lastname: Connor
authors.forename: D
authors.initials: D
authors.lastname: Sayers
authors.forename: D R
authors.initials: DR
authors.lastname: Sumner
authors.forename: Z
authors.initials: Z
authors.lastname: Zhong
mesh_terms: D000818:Animals; D001858:Bone Nails; D002417:Cattle; D019544:Equipment Failure Analysis / Q000379:methods*; D005592:Fracture Fixation / Q000295:instrumentation*; D050723:Fractures, Bone / Q000000981:diagnostic imaging*; D066298:In Vitro Techniques; D008670:Metals; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D017356:Synchrotrons; D016896:Treatment Outcome; D014961:X-Ray Diffraction / Q000379:methods*
chemical_list: D008670:Metals