Epithelial cell migration in response to epidermal growth factor.
Epidermal growth factor (EGF) is a ligand for the EGF receptor, a member of the erbB family of receptor tyrosine kinases. Activation of EGF receptor by EGF or other high-affinity ligands often results in increased migration of cells in physiological and pathological situations. There are numerous approaches for evaluating cell migratory response following EGF stimulation. Both qualitative and quantitative techniques will be presented in this chapter.
Zeineldin
Reema
R
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque, USA.
Hudson
Laurie G
LG
D002465:Cell Movement / Q000187:drug effects*; D002478:Cells, Cultured; D017097:Electric Impedance; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D066246:ErbB Receptors / Q000037:antagonists & inhibitors; D006801:Humans; D015603:Keratinocytes / Q000166:cytology* / Q000187:drug effects*
D004815:Epidermal Growth Factor; D066246:ErbB Receptors