[The ethiology, pathogenesis, and treatment of Helicobacter pylori-associated peptic ulcer: the status of the problem and the prospects].
The author presents an objective, evidence-based analysis of the main conceptions of the infectious theory of peptic ulcer (PU), critically discussing such postulates as "no Helicobacter pylori (HB), no PU", "HP is a pathogen that presents the main cause of PU", "a good HP is a dead HP", "HP eradication leads to complete recovery from PU", etc. The article presents original author's concepts on interrelations between HP infection and the human organism, and the pathogenesis of HP-associated PU. The consequences of the practical realization of the recommendations of Maastrich Consensus on HP eradication are discussed. The data of the author's studies dedicated to the ways of increasing the effectiveness of treatment of HP-associated PU, based on the author's conception of its pathogenesis, are adduced.
Tsimmerman
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D000890:Anti-Infective Agents / Q000627:therapeutic use; D016480:Helicobacter pylori / Q000472:pathogenicity*; D006801:Humans; D010437:Peptic Ulcer / Q000209:etiology / Q000382:microbiology / Q000628:therapy; D054328:Proton Pump Inhibitors; D012307:Risk Factors; D013276:Stomach Ulcer / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology
D000890:Anti-Infective Agents; D054328:Proton Pump Inhibitors