title: Emerging evidence for the use of insulin pump therapy in infants, toddlers, and preschool-aged children with type 1 diabetes.
abstract: Insulin pump therapy has, within the last 10 years, emerged as an increasingly popular modality of treatment to achieve intensive glycemic targets in type 1 diabetes (T1D). The evidence for the benefits of pump therapy has been demonstrated in adults and adolescents; however, until recently there has been a paucity of studies examining the efficacy and safety in pump therapy in very young children. The purpose of this article is to discuss the rationale for insulin pump therapy in infants and toddlers, review the available studies of pump therapy in this population, and show that the data support the use of insulin pumps in our very youngest of patients.
authors.affiliation: Department of Pediatrics and the General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520, USA. stuart.weinzimer@yale.edu
authors.forename: Stuart A
authors.initials: SA
authors.lastname: Weinzimer
authors.forename: Karena L
authors.initials: KL
authors.lastname: Swan
authors.forename: Kristin A
authors.initials: KA
authors.lastname: Sikes
authors.forename: Joann H
authors.initials: JH
authors.lastname: Ahern
mesh_terms: D017028:Caregivers / Q000523:psychology; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007003:Hypoglycemia / Q000517:prevention & control; D007223:Infant; D007231:Infant, Newborn; D015918:Infusion Pumps, Implantable; D007328:Insulin / Q000627:therapeutic use*; D007332:Insulin Infusion Systems; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic
chemical_list: D006442:Glycated Hemoglobin; D007328:Insulin