Caspofungin treatment in two infants with persistent fungaemia due to Candida lipolytica.
Candida lipolytica has infrequently been identified as a cause of infection and is associated mostly with vascular catheter-related fungaemia. Patients reported in the literature have been successfully treated with catheter removal or amphotericin B treatment. We report 2 infants with C. lipolytica fungaemia unresponsive to catheter removal and amphotericin B therapy and treated successfully with the addition of caspofungin to amphotericin B.
Belet
Nurşen
N
Department of Paediatrics, Section of Infectious Diseases, Ankara University Medical School, Turkey. nurbelet@yahoo.com
Ciftçi
Ergin
E
Ince
Erdal
E
Dalgiç
Nazan
N
Oncel
Selim
S
Güriz
Haluk
H
Yagmurlu
Aydin
A
Dindar
Hüseyin
H
Doğru
Ulker
U
D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage*; D002175:Candida / Q000302:isolation & purification; D000077336:Caspofungin; D002408:Catheters, Indwelling / Q000009:adverse effects / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology; D004359:Drug Therapy, Combination; D054714:Echinocandins; D005260:Female; D016469:Fungemia / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D055666:Lipopeptides; D008297:Male; D010456:Peptides, Cyclic / Q000008:administration & dosage
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D000666:Amphotericin B; D000077336:Caspofungin