[Clinical peculiarities of diffuse toxic goiter in males].
A comparative analysis of thyrotoxicosis in 180 males and 121 females has shown that during the recent 15 years the number of males operated upon for diffuse toxic goiter (DTG) has become 2.6 times greater. Thyrotoxicosis in men is characterized by an aggressive course, is followed by cardiac complications, ophthalmopathy, impaired sexual function, appearance of foci of malignant growth, spread of diffuse hyperplasia of the thyroid gland behind the breast bone and trachea. Cessation of thyreostatic therapy resulted in quick recurrence of the disease. Repeated courses of treatment with thyreostatics increased the risk of irreversibility of changes in the heart muscle, impairment of regenerative abilities and massive lymphoid infiltration of the thyroid tissue followed by hypothyrosis. Early surgical treatment of men with DTG facilitated a rapid and reliable restoration of vitally important functions and recovery of most operated men and women.
Romanchishen
A F
AF
Volert
V A
VA
D000293:Adolescent; D000328:Adult; D000368:Aged; D018450:Disease Progression; D005260:Female; D006044:Goiter, Nodular / Q000453:epidemiology / Q000601:surgery; D049970:Graves Ophthalmopathy / Q000453:epidemiology; D006801:Humans; D007037:Hypothyroidism / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis / Q000379:methods; D015995:Prevalence; D012720:Severity of Illness Index; D012737:Sex Factors; D013971:Thyrotoxicosis / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy*