Closing the link in short-loop prolactin feedback.
Short-loop negative feedback actions of prolactin in hypothalamus have been recognized for some time. Two recent papers demonstrate the multiple sites of this feedback action and the signaling mechanisms involved.
White
Meghan M
MM
Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St. Louis, MO 63104, USA.
Samson
Willis K
WK
D000818:Animals; D000833:Animals, Suckling; D025461:Feedback, Physiological; D005260:Female; D007031:Hypothalamus / Q000378:metabolism; D007774:Lactation / Q000378:metabolism; D051379:Mice; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D011981:Receptors, Prolactin / Q000378:metabolism; D014018:Tissue Distribution
D011981:Receptors, Prolactin; D011388:Prolactin