title: [Complete heart block due to Wegener's granulomatosis: a case report and literature review].
abstract: Involvement of the conduction system of the heart in Wegener's granulomatosis (WG) is rare. We present a 53-year-old man with WG pulmonary, renal and left eyeball involvement and with a high initial level of cANCA (1: 640). He was treated with steroids, cyclophosphamide and cyclosporine. After 14 months he presented with lethargy and presyncope due to a complete atrio-ventricular block with an escape rhythm of 35 beats/min. The temporary pacing electrode was inserted, followed by permanent DDDR pacemaker implantation on the third day as the block persisted despite WG treatment intensification. Clinical picture showed the disease in a progressive state.
authors.affiliation: Oddział Chorób Wewnetrznych, Szpital Miejski ZOZ Nowe Miasto, ul. Szwajcarska 3, 61-285 Poznań. welikowski@wp.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Elikowski
authors.forename: Artur
authors.initials: A
authors.lastname: Baszko
authors.forename: Mariusz
authors.initials: M
authors.lastname: Puszczewicz
authors.forename: Ewa
authors.initials: E
authors.lastname: Stachura
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D002304:Cardiac Pacing, Artificial; D003520:Cyclophosphamide / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D006327:Heart Block / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D035583:Rare Diseases; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D003520:Cyclophosphamide