title: [Optic nerve atrophy after vitrectomy for diabetic retinopathy: its systemic and local risk factors].
abstract: OBJECTIVE
  To evaluate the incidence and risk factors of optic nerve atrophy after vitrectomy for diabetic retinopathy.
  
  
  METHODS
  Clinical charts of 48 eyes of 40 patients who underwent vitrectomy for diabetic retinopathy were retrospectively reviewed. The relationship between postoperative optic nerve atrophy and patients' physical condition was statistically analyzed.
  
  
  RESULTS
  Postoperative optic nerve atrophy, distinct from glaucomatous optic nerve atrophy, occurred in 5 eyes (10.4%). Its incidence was correlated with higher plasma creatinine concentration (p=0.001), proliferative diabetic retinopathy (p= 0.046), and retinal white vessel formation (p= 0.007). Maintenance of the best postoperative visual acuity was difficult in the patients with optic nerve atrophy.
  
  
  CONCLUSIONS
  Patients with proliferative diabetic retinopathy accompanied by renal dysfunction were at high risk of optic nerve atrophy after vitrectomy.
authors.affiliation: Department of Ophthalmology, Saiseikai Niigata Daini Hospital, Niigata 950-1104, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Seki
authors.forename: Hajime
authors.initials: H
authors.lastname: Togashi
authors.forename: Noburo
authors.initials: N
authors.lastname: Ando
mesh_terms: D000328:Adult; D000368:Aged; D001284:Atrophy; D003930:Diabetic Retinopathy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000473:pathology*; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D014821:Vitrectomy