An endoscopically proven ventriculitis-type, cyst-like intraventricular primary lymphoma of the central nervous system.
Primary ventriculitis form of primary CNS lymphoma (PCNSL) is very rare and difficult to diagnose from radiological findings. A 55-year-woman presented with a cystic mass in the lateral ventricle without evidence of demonstrable malignant cells in the cerebrospinal fluid (CSF). The endoscopic biopsy showed a ventriculitis-like thin web on the surface of the ventricular wall around the foramen of Monro, resulting in obstruction. Pathological diagnosis was non-Hodgkin's lymphoma, B cell type. This case suggests that PCNSL should be considered as a differential diagnosis for a cystic ventricular lesion even with no malignant cells in the CSF.
Park
S W
SW
Department of Neurosurgery, Kangwon National University College of Medicine, Chunchon, Korea.
Yoon
S H
SH
Cho
K G
KG
D018951:Antigens, CD20 / Q000032:analysis / Q000378:metabolism; D001706:Biopsy; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000503:physiopathology; D020863:Central Nervous System Cysts / Q000175:diagnosis*; D002551:Cerebral Ventricle Neoplasms / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000503:physiopathology; D002552:Cerebral Ventricles / Q000473:pathology / Q000503:physiopathology; D002555:Cerebrospinal Fluid / Q000166:cytology; D002557:Cerebrospinal Fluid Shunts; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D020547:Lateral Ventricles / Q000473:pathology* / Q000503:physiopathology; D017493:Leukocyte Common Antigens / Q000032:analysis / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011878:Radiotherapy
D018951:Antigens, CD20; D017493:Leukocyte Common Antigens