title: Cerebral metastasis of cervical uterine cancer: report of three cases.
abstract: Cervical uterine cancer (CUC) spreads locally (pelvis and paraortic lymphnodes) or distantly (lungs, liver and bones). Metastasis to central nervous system (CNS) are rare. There are about 80 cases reported in the literature. Outcome is poor and survival varies from 3 to 6 months. Three cases of CNS metastasis from CUC are reported, one infratentorial and two supratentorials in location. In one patient, the initial manifestation was due to the cerebral lesion, a feature reported for the first time. All cases were treated by surgery, radiotherapy and/or chemotherapy. Clinical findings and treatment options of these rare lesions are reviewed.
authors.affiliation: Department of Neurosurgery, Hospital Nossa Senhora das Graças, Curitiba, PR, and Federal University of Sergipe, Aracaju, SE, Brazil. joacirgc@hotmail.com
authors.forename: Joacir Graciolli
authors.initials: JG
authors.lastname: Cordeiro
authors.forename: Daniel Monte-Serrat
authors.initials: DM
authors.lastname: Prevedello
authors.forename: Léo Fernando
authors.initials: LF
authors.lastname: da Silva Ditzel
authors.forename: Carlos Umberto
authors.initials: CU
authors.lastname: Pereira
authors.forename: João Cândido
authors.initials: JC
authors.lastname: Araújo
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D003399:Craniotomy; D005260:Female; D006801:Humans; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000473:pathology*