title: Synthesis of a red-shifted fluorescence polarization probe for Hsp90.
abstract: The synthesis of a red-shifted cy3B-GM ligand and its evaluation as a fluorescence polarization probe for Hsp90 is presented.
authors.affiliation: Program in Molecular Pharmacology and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
authors.forename: Kamalika
authors.initials: K
authors.lastname: Moulick
authors.forename: Cristina C
authors.initials: CC
authors.lastname: Clement
authors.forename: Julia
authors.initials: J
authors.lastname: Aguirre
authors.forename: Joungnam
authors.initials: J
authors.lastname: Kim
authors.forename: Yanlong
authors.initials: Y
authors.lastname: Kang
authors.forename: Sara
authors.initials: S
authors.lastname: Felts
authors.forename: Gabriela
authors.initials: G
authors.lastname: Chiosis
mesh_terms: D016227:Benzoquinones / Q000737:chemistry*; D002232:Carbocyanines / Q000138:chemical synthesis / Q000737:chemistry*; D003116:Color; D005454:Fluorescence Polarization; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D018841:HSP90 Heat-Shock Proteins / Q000737:chemistry* / Q000145:classification; D047029:Lactams, Macrocyclic / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D017828:Rifabutin / Q000737:chemistry*
chemical_list: D016227:Benzoquinones; D002232:Carbocyanines; D005456:Fluorescent Dyes; D018841:HSP90 Heat-Shock Proteins; D047029:Lactams, Macrocyclic; D008024:Ligands; C089187:cyanine dye 3; D017828:Rifabutin; C001277:geldanamycin