title: [Dental implants in irradiated areas: a series of 33 patients].
abstract: BACKGROUND
  Prosthetic rehabilitation, particularly in radiated areas, can be particularly difficult in patients with partial or total edentation following treatment for orofacial cancer. We report a series of patients who underwent a protocol of implantation in radiated bone with evaluation of the prosthetic rehabilitation.
  
  
  METHODS
  Thirty-three patients given radiotherapy for an orofacial cancer were implanted, followed by a dental prosthesis. The three phases of the protocol were a preoperative clinical and radiological analysis, a surgical phase under general anaesthesia and a postoperative clinical and radiological follow-up.
  
  
  RESULTS
  Fifteen patients were treated for an oral cavity tumor, ten for a pharyngeal lesion, six for a laryngeal tumor and two for a maxillary cancer. The average dose of radiotherapy was 60.5 Gy. Sixty-eight implants were positioned, 91.9% in the anterior mandible. The delay between radiotherapy and implantation was 54 months. The delay between implantation and loading was seven months. The average follow-up was 31.9 months. No peri-implantitis was observed.
  
  
  CONCLUSIONS
  Implantation in irradiated bone is possible if a strict protocol is used; a good rate of success and improved quality of life will favour development of this technique. Criteria for dental implant placement include local and general conditions, the psychological situation and technical possibilities. Sufficient delay after radiotherapy is necessary to verify healing and the good prognosis of the cancer. The vascular supply can be preserved by implantation under general anesthesia. All patients were satisfied with the functional and esthetic results.
authors.affiliation: Unité d'Odontologie, Service de Chirurgie, Centre Léon Bérard, Lyon. bodard@lyon.fnclcc.fr
authors.forename: A G
authors.initials: AG
authors.lastname: Bodard
authors.forename: R
authors.initials: R
authors.lastname: Gourmet
authors.forename: R
authors.initials: R
authors.lastname: Lucas
authors.forename: E
authors.initials: E
authors.lastname: Bonnet
authors.forename: P
authors.initials: P
authors.lastname: Breton
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016371:Cranial Irradiation; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy / Q000534:rehabilitation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants