title: Polyphenol-enriched oolong tea increases fecal lipid excretion.
abstract: OBJECTIVE
  To assess possibility of polyphenol-enriched oolong tea to reduce dietary lipid absorption in humans.
  
  
  METHODS
  Twelve healthy adult subjects, three males and nine females, aged (mean+/-s.d.) 22.0+/-1.8 years, respectively, were randomly divided into two groups. The participants were followed a double-blind placebo-controlled crossover design, including 7-day washout periods and 10-day treatment periods. During the treatment periods, subjects were given about 38 g of lipids from potato chips (19 g each within 30 min after lunch and dinner) and total 750 ml beverages (placebo- or polyphenol-enriched oolong tea) at three meals. Blood samples were collected for biochemical examination at days 8, 18, 25 and 35 of the study period. On the last 3 days of each treatment period, feces were collected to measure the excretion of lipids.
  
  
  RESULTS
  Lipid excretion into feces was significantly higher in the polyphenol-enriched oolong tea period (19.3+/-12.9 g/3 day) than in the placebo period (9.4+/-7.3 g/3 day) (P < 0.01). Cholesterol excretion tended to increase in polyphenol-enriched oolong tea period (1.8+/-1.2 g/3 day) compared with that of placebo (1.2+/-0.6 g/3 day) (P = 0.056).
  
  
  CONCLUSIONS
  The results of this study indicated that polyphenol-enriched oolong tea could increase lipid excretion into feces when subjects took high-lipid diet.
authors.affiliation: International Public Health Nutrition, Graduate School of Health Biosciences, The University of Tokushima, Tokushima, Japan.
authors.forename: T-F
authors.initials: TF
authors.lastname: Hsu
authors.forename: A
authors.initials: A
authors.lastname: Kusumoto
authors.forename: K
authors.initials: K
authors.lastname: Abe
authors.forename: K
authors.initials: K
authors.lastname: Hosoda
authors.forename: Y
authors.initials: Y
authors.lastname: Kiso
authors.forename: M-F
authors.initials: MF
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000032:analysis / Q000378:metabolism; D018592:Cross-Over Studies; D004041:Dietary Fats / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004311:Double-Blind Method; D005243:Feces / Q000737:chemistry*; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D005527:Food, Fortified; D006801:Humans; D006937:Hypercholesterolemia / Q000178:diet therapy; D007408:Intestinal Absorption / Q000187:drug effects*; D008055:Lipids / Q000032:analysis*; D008297:Male; D009765:Obesity / Q000178:diet therapy; D010636:Phenols / Q000494:pharmacology*; D059808:Polyphenols; D013662:Tea
chemical_list: D004041:Dietary Fats; D005419:Flavonoids; D008055:Lipids; D010636:Phenols; D059808:Polyphenols; D013662:Tea; D002784:Cholesterol