title: Mesenteric adenitis caused by Yersinia pseudotubercolosis in a patient subsequently diagnosed with Crohn's disease of the terminal ileum.
abstract: Although the association between inflammatory bowel disease and gastrointestinal infections has been suggested, the mechanisms involved in the pathogenesis of Crohn's disease (CD) are still undetermined. We report the case of a man, who presented with mesenteric adenitis initially due to a Yersinia pseudotubercolosis infection, who was later diagnosed with Crohn's disease. This case is in keeping with recent evidence in the literature which suggests that CD is a disease linked to abnormal immune responses to enteric bacteria in genetically susceptible individuals.
authors.affiliation: Department of Clinical Sciences, Umberto I Viale del Policlinico 155, Rome, Italy. maddyzip@yahoo.it
authors.forename: Maddalena
authors.initials: M
authors.lastname: Zippi
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: Colaiacomo
authors.forename: Adriana
authors.initials: A
authors.lastname: Marcheggiano
authors.forename: Roberta
authors.initials: R
authors.lastname: Pica
authors.forename: Paolo
authors.initials: P
authors.lastname: Paoluzi
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Iaiani
authors.forename: Renzo
authors.initials: R
authors.lastname: Caprilli
authors.forename: Francesca
authors.initials: F
authors.lastname: Maccioni
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000276:immunology; D003424:Crohn Disease / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D020022:Genetic Predisposition to Disease; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology / Q000235:genetics / Q000473:pathology; D007082:Ileum / Q000473:pathology; D008297:Male; D008640:Mesenteric Lymphadenitis / Q000150:complications* / Q000276:immunology / Q000382:microbiology*; D015011:Yersinia pseudotuberculosis / Q000276:immunology / Q000472:pathogenicity*; D015012:Yersinia pseudotuberculosis Infections / Q000150:complications* / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D000949:Histocompatibility Antigens Class II