title: Autologous transplantation of CD133+ BM-derived stem cells as a therapeutic option for dilatative cardiomyopathy.
abstract: We report the case of a 58-year-old man with end-stage non-ischemic cardiomyopathy. Baseline transthoracic echocardiography (TTE) and cardiac magnetic resonance (cMRI) revealed a markedly depressed left ventricle systolic function. He underwent autologous CD133+ BM-derived cell transplantation through a minimally invasive approach. During surgery 19 x 10(6) BM-derived stem cells were injected by the transepimyocardial route. Six months after the operation TTE and cMRI showed a clear improvement in left ventricular contractility.
authors.forename: A
authors.initials: A
authors.lastname: Ghodsizad
authors.forename: A
authors.initials: A
authors.lastname: Ruhparwar
authors.forename: R
authors.initials: R
authors.lastname: Marktanner
authors.forename: A
authors.initials: A
authors.lastname: Borowski
authors.forename: M R
authors.initials: MR
authors.lastname: Mohammad Hasani
authors.forename: L
authors.initials: L
authors.lastname: Poll
authors.forename: I
authors.initials: I
authors.lastname: Vshivkov
authors.forename: V
authors.initials: V
authors.lastname: Stoldt
authors.forename: T
authors.initials: T
authors.lastname: Voelkel
authors.forename: C
authors.initials: C
authors.lastname: Piechaczek
authors.forename: E R
authors.initials: ER
authors.lastname: Burchardt
authors.forename: M
authors.initials: M
authors.lastname: Stockschlaeder
authors.forename: C
authors.initials: C
authors.lastname: Sucker
authors.forename: E
authors.initials: E
authors.lastname: Gams
authors.forename: H M
authors.initials: HM
authors.lastname: Klein
mesh_terms: D000071916:AC133 Antigen; D015703:Antigens, CD / Q000032:analysis*; D001854:Bone Marrow Cells / Q000737:chemistry / Q000166:cytology; D016026:Bone Marrow Transplantation / Q000379:methods*; D002311:Cardiomyopathy, Dilated / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D004452:Echocardiography; D006023:Glycoproteins / Q000032:analysis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000032:analysis*; D013234:Stem Cells / Q000737:chemistry / Q000166:cytology*; D013318:Stroke Volume / Q000502:physiology; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D000071916:AC133 Antigen; D015703:Antigens, CD; D006023:Glycoproteins; C000606023:PROM1 protein, human; D010455:Peptides