title: Designer macrophages: oxidative metabolism fuels inflammation repair.
abstract: Macrophages play a central role in immunity, contributing to both the initiation and resolution of inflammation. In this issue of Cell Metabolism, Vats et al. provide insight into the mechanisms by which reparative macrophages are generated and reveal a previously unappreciated link between this anti-inflammatory axis and mitochondrial oxidative metabolism (Vats el al., 2006).
authors.affiliation: Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
authors.forename: Adam
authors.initials: A
authors.lastname: Lacy-Hulbert
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Moore
mesh_terms: D000818:Animals; D004734:Energy Metabolism; D005227:Fatty Acids / Q000378:metabolism; D007249:Inflammation / Q000378:metabolism*; D015847:Interleukin-4 / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D008954:Models, Biological
chemical_list: D005227:Fatty Acids; D015847:Interleukin-4