title: Attentional deficits affect activities of daily living in dementia-associated with Parkinson's disease.
abstract: OBJECTIVE
  To investigate the effects of attentional deficits on activities of daily living (ADL) in patients with dementia associated with Parkinson's disease (PDD).
  
  
  METHODS
  461 patients were assessed neuropsychologically. Factor analyses were used to differentiate attention from other cognitive functions and to differentiate different aspects of ADL functions. The effects of the attentional measure on ADL were examined using sequential multiple regression, controlling for age, sex, education, severity of motor symptoms and other cognitive functions.
  
  
  RESULTS
  Three cognitive factors were identified, with one factor emerging as a measure of vigilance and focused attention. This factor predicted different aspects of ADL status even after controlling for motor functions and other cognitive factors. The attention factor was the single strongest cognitive predictor of ADL status, matching the strength of the effects of motor functions on ADL status.
  
  
  CONCLUSIONS
  Impaired attention is an important determinant of ADL functions in patients with PDD.
authors.affiliation: Psychiatric Clinic, Stavanger University Hospital, Helse Stavanger, Post Box 8100, 4068 Stavanger, Norway. bronnick@gmail.com
authors.forename: K
authors.initials: K
authors.lastname: Bronnick
authors.forename: U
authors.initials: U
authors.lastname: Ehrt
authors.forename: M
authors.initials: M
authors.lastname: Emre
authors.forename: P P
authors.initials: PP
authors.lastname: De Deyn
authors.forename: K
authors.initials: K
authors.lastname: Wesnes
authors.forename: S
authors.initials: S
authors.lastname: Tekin
authors.forename: D
authors.initials: D
authors.lastname: Aarsland
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D001288:Attention; D003071:Cognition; D003430:Cross-Sectional Studies; D003704:Dementia / Q000209:etiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology*; D012720:Severity of Illness Index