title: Comorbidity of schizophrenia and cancer: clinical recommendations for treatment.
abstract: The paper analyzes some issues on the comorbidity between schizophrenia and cancer. Epidemiological studies have reported contradictory results, but it is certain that patients with schizophrenia are more likely to suffer from risk factors for cancer development, such as increased alcohol abuse, obesity, nicotine dependence and decreased physical activity. The paper gives guidelines for the treatment of cancer in patients with schizophrenia, and discusses possible interactions between chemotherapy and psychotropic drugs. Particular attention is paid to the use of antipsychotics which increase the level of prolactin, in view of the possible risk of breast and endometrial cancer in patients with schizophrenia.
authors.affiliation: Institute for Psychiatry, Clinical Centre of Serbia, Belgrade, Serbia and Montenegro. salt@eunet.yu
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Damjanović
authors.forename: Maja
authors.initials: M
authors.lastname: Ivković
authors.forename: Miroslava
authors.initials: M
authors.lastname: Jasović-Gasić
authors.forename: Vladimir
authors.initials: V
authors.lastname: Paunović
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002455:Cell Division / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D015897:Comorbidity; D004347:Drug Interactions; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D014150:Antipsychotic Agents