title: [Unusual outcome of mitral valve infectious endocarditis in a premature infant].
abstract: The authors report a case of Staphylococcus Aureus infectious endocarditis in a premature baby. Echocardiography on the 8th day of life showed a large vegetation on the anterior mitral leaflet without significant regurgitation. Intravenous antibiotics and platelet antiaggregant therapy were given. At three weeks of age the vegetation split into two, one part attached to the foramen ovale and the other to the anterior mitral leaflet. At one month, the development of severe mitral regurgitation led to surgical valvuloplasty in a 2 kg neonate, the vegetation on the foramen ovale having spontaneously fragmented. The ablation of the mitral vegetation associated with commissuroplasty reduced the mitral regurgitation. At 3 months after surgery, the child was asymptomatic with a minimal mitral regurgitation.
authors.affiliation: Unité de cardiologie pédiatrique, Hôpital des Enfants, Toulouse.
authors.forename: A
authors.initials: A
authors.lastname: Zabalawi
authors.forename: A
authors.initials: A
authors.lastname: Taktak
authors.forename: R
authors.initials: R
authors.lastname: Bassil
authors.forename: S
authors.initials: S
authors.lastname: Paranon
authors.forename: O
authors.initials: O
authors.lastname: Ghez
authors.forename: B
authors.initials: B
authors.lastname: Kreitmann
authors.forename: Y
authors.initials: Y
authors.lastname: Dulac
authors.forename: P
authors.initials: P
authors.lastname: Acar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010975:Platelet Aggregation Inhibitors