title: Bacterial resistance: a sensitive issue complexity of the challenge and containment strategy in Europe.
abstract: The development of antimicrobial agents has been a key achievement of modern medicine. However, their overuse has led to an increasing incidence of infections due to antibiotic-resistant microorganisms. Quantitative figures on the current economic and health impact of antimicrobial resistance are scant, but it is clearly a growing challenge that requires timely action. That action should be at the educational, ethical, economic and political level. An important first step would be to increase public awareness and willingness to take the necessary measures to curb resistance. Hence, studies are needed that would provide solid, quantitative data on the societal impact of antibiotic resistance. This review discusses the complexity of resistance, identifies its main drivers and proposes measures to contain it on a European scale.
authors.affiliation: Eijkman-Winkler Institute, University Medical Center Utrecht, UMCU G04-614, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. W.T.M.Jansen@umcutrecht.nl <W.T.M.Jansen@umcutrecht.nl>
authors.forename: W T M
authors.initials: WT
authors.lastname: Jansen
authors.forename: J T
authors.initials: JT
authors.lastname: van der Bruggen
authors.forename: J
authors.initials: J
authors.lastname: Verhoef
authors.forename: A C
authors.initials: AC
authors.lastname: Fluit
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000382:microbiology; D003140:Communicable Disease Control / Q000639:trends*; D024881:Drug Resistance, Bacterial; D005060:Europe; D006801:Humans; D011634:Public Health
chemical_list: D000900:Anti-Bacterial Agents