title: Comparative in vitro study of bileaflet and tilting disk valve behavior in the pulmonary position.
abstract: A study of mechanical heart valve behavior in the pulmonary position as a function of pulmonary vascular resistance is reported for the St. Jude Medical bileaflet (SJMB) valve and the MedicalCV Omnicarbon (OTD) tilting disk valve. Tests were conducted in a pulmonic mock circulatory system and impedance was varied in terms of system pulmonary vascular resistance (PVR). An impedance spectrum was found using instantaneous pulmonary artery pressure and flow rate curves. Both valves fully opened and closed at and above a nominal PVR of 3.0 mmHg/L/min. The SJMB valve was prone to leaflet bounce at closure, but otherwise completely closed, at settings above and below this nominal setting. At PVR values at and below 2.0 mmHg/L/min, the SJMB valve exhibited two types of leaflet aberrant behavior: single leaflet only closure while the other leaflet fluttered, and incomplete closure where both leaflets flutter but neither remain fully closed. The OTD valve fully opened and closed to a PVR value of 1.6 mmHg/L/min. At lower values, the valve did not close. Valves designed for the left heart can show aberrant behavior under normal conditions as pulmonary valves.
authors.affiliation: Department of Mechanical Engineering and Bioengineering, Clemson University, Clemson, SC 29634-0921, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Gohean
authors.forename: Richard
authors.initials: R
authors.lastname: Figliola
authors.forename: Tiffany
authors.initials: T
authors.lastname: Camp
authors.forename: Tim
authors.initials: T
authors.lastname: McQuinn
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure; D019544:Equipment Failure Analysis; D006350:Heart Valve Prosthesis; D006801:Humans; D011474:Prosthesis Design; D011651:Pulmonary Artery / Q000503:physiopathology*; D011664:Pulmonary Valve / Q000503:physiopathology* / Q000601:surgery*; D016896:Treatment Outcome