title: Health-related quality of life of HIV-infected children on complex antiretroviral therapy at home.
abstract: The study describes quality of life as perceived by parents and measured by the Child Health Questionnaire (CHQ-28) for a convenience sample of 33 HIV-infected children age 5 to 18 years cared for at home on complex antiretroviral drug regimens. When compared with normative data on healthy U.S. children, parent reports for the HIV-infected children did not differ significantly on the following CHQ concepts: role/social related to emotional, behavioral or physical problems; bodily pain; behavior; mental health; self-esteem; impact on parental time; family activities; and family cohesion. Parents perceived their children to be functioning at a level significantly lower than the norm in general health (t -6.47, p = .000), physical functioning (t -2.37, p = .024), and physical summary (t -3.80, p = .001). Parental impact-emotional was impressively higher than the norm (t -3.74, p = .001). Differences were independent of gender, primary language, ethnicity, and Centers for Disease Control and Prevention clinical classifications for pediatric HIV disease.
authors.affiliation: Columbia University School of Nursing, USA.
authors.forename: Mary Woods
authors.initials: MW
authors.lastname: Byrne
authors.forename: Judy
authors.initials: J
authors.lastname: Honig
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D023241:Antiretroviral Therapy, Highly Active; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008297:Male; D009511:New England; D002666:Psychology, Child; D011788:Quality of Life