title: Vanishing white matter disease with periodic (paroxysmal) hemiparesis.
abstract: Vanishing white matter disease is a chronically progressive leukodystrophy with periods of acute deterioration after head trauma and febrile illness. This report describes a child with genetically and clinically confirmed vanishing white matter disease exhibiting frequent episodes of right-sided hemiplegia, aphasia, and headache resolving fully within hours to days. This report describes a case of this condition presenting with episodes of hemiparesis with full discovery to baseline. Some possible mechanisms explaining this unusual presentation are provided.
authors.affiliation: Division of Neurology, Department of Pediatrics, University of Alberta, Edmonton, Canada.
authors.forename: Vijay
authors.initials: V
authors.lastname: Ramaswamy
authors.forename: Alicia K
authors.initials: AK
authors.lastname: Chan
authors.forename: Hanna K
authors.initials: HK
authors.lastname: Kolski
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D020279:Hereditary Central Nervous System Demyelinating Diseases / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D006801:Humans; D008297:Male; D010291:Paresis / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology