title: Smokers with airway obstruction are more likely to quit smoking.
abstract: BACKGROUND
  Chronic obstructive pulmonary disease (COPD), usually caused by tobacco smoking, is one of the leading causes of morbidity and mortality. Smoking cessation at an early stage of the disease usually stops further progression. A study was undertaken to determine if diagnosis of airway obstruction was associated with subsequent success in smoking cessation, as advised by a physician.
  
  
  METHODS
  4494 current smokers (57.4% men) with a history of at least 10 pack-years of smoking were recruited from 100 000 subjects screened by spirometric testing for signs of airway obstruction. At the time of screening all received simple smoking cessation advice. 1177 (26.2%) subjects had airway obstruction and were told that they had COPD and that smoking cessation would halt rapid progression of their lung disease. No pharmacological treatment was proposed. After 1 year all subjects were invited for a follow up visit. Smoking status was assessed by history and validated by exhaled carbon monoxide level.
  
  
  RESULTS
  Nearly 70% attended a follow up visit (n = 3077): 61% were men, mean (SD) age was 52 (10) years, mean (SD) tobacco exposure 30 (17) pack-years, and 33.3% had airway obstruction during the baseline examination. The validated smoking cessation rate in those with airway obstruction was 16.3% compared with 12.0% in those with normal spirometric parameters (p = 0.0003). After correction for age, sex, nicotine dependence, number of cigarettes smoked daily, and lung function, success in smoking cessation was predicted by lower lung function, lower nicotine dependence, and lower tobacco exposure.
  
  
  CONCLUSIONS
  Simple smoking cessation advice combined with spirometric testing resulted in good 1 year cessation rates, especially in subjects with airway obstruction.
authors.affiliation: National Research Institute of Tuberculosis and Lung Diseases, 2nd Department of Respiratory Medicine, 26 Plocka Street, 01-138 Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Bednarek
authors.forename: D
authors.initials: D
authors.lastname: Gorecka
authors.forename: J
authors.initials: J
authors.lastname: Wielgomas
authors.forename: M
authors.initials: M
authors.lastname: Czajkowska-Malinowska
authors.forename: J
authors.initials: J
authors.lastname: Regula
authors.forename: G
authors.initials: G
authors.lastname: Mieszko-Filipczyk
authors.forename: M
authors.initials: M
authors.lastname: Jasionowicz
authors.forename: R
authors.initials: R
authors.lastname: Bijata-Bronisz
authors.forename: M
authors.initials: M
authors.lastname: Lempicka-Jastrzebska
authors.forename: M
authors.initials: M
authors.lastname: Czajkowski
authors.forename: G
authors.initials: G
authors.lastname: Przybylski
authors.forename: J
authors.initials: J
authors.lastname: Zielinski
mesh_terms: D003376:Counseling; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology*; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology / Q000523:psychology; D016540:Smoking Cessation; D016896:Treatment Outcome; D014797:Vital Capacity / Q000502:physiology