title: Double laparotomy wound recurrence of endometrial carcinoma.
abstract: BACKGROUND
  Abdominal scar recurrence of endometrial carcinoma after abdominal total hysterectomy is very rare. We report a case of a 65-year-old woman who had two recurrences in the abdominal incisional scar after total hysterectomy.
  
  
  METHODS
  A 65-year-old woman underwent total hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy because of well-differentiated endometrial adenocarcinoma (Stage IIB). Thus, the patient was treated by external beam radiotherapy. She developed two recurrences in the abdominal incisional scar two and three years after total hysterectomy, respectively. Surgery plus chemotherapy and surgery plus hormonal therapy were used for treatment of the first and second scar recurrence, respectively.
  
  
  CONCLUSIONS
  It is a very intriguing and controversial biologic question how neoplastic cells can implant and grow in an abdominal scar without other concomitant metastases. We report a review of the literature and the possible mechanism of recurrences in laparotomy wounds.
authors.affiliation: Department of Obstetrics and Gynecology, Department of Pathological Anatomy, L. Armanni Second University of Naples (SUN), Naples, Italy.
authors.forename: G C
authors.initials: GC
authors.lastname: Balbi
authors.forename: A
authors.initials: A
authors.lastname: Cardone
authors.forename: A
authors.initials: A
authors.lastname: Monteverde
authors.forename: M
authors.initials: M
authors.lastname: Passaro
authors.forename: L
authors.initials: L
authors.lastname: Montone
authors.forename: R
authors.initials: R
authors.lastname: Rossiello
authors.forename: S
authors.initials: S
authors.lastname: Visconti
authors.forename: M
authors.initials: M
authors.lastname: Battista
authors.forename: M
authors.initials: M
authors.lastname: Battisti
authors.forename: E
authors.initials: E
authors.lastname: Cassese
authors.forename: I
authors.initials: I
authors.lastname: Landino
mesh_terms: D034861:Abdominal Wall; D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D002921:Cicatrix / Q000209:etiology / Q000473:pathology; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007813:Laparotomy; D009364:Neoplasm Recurrence, Local; D009366:Neoplasm Seeding