[Merkel cell carcinoma in a patient with chronic lymphocytic leukemia].
Merkel cell carcinoma (MCC) is an infrequent neuroendocrine tumor of the skin with a high potential for local recurrence, lymphatic dissemination and distant dissemination. We present a case of MCC in a male patient with chronic lymphocytic leukemia (CLL). The immunosuppression induced by the leukemia or by the chemotherapy could play a pathogenic role in the association of these diseases. Positron emission tomography (PET) was a useful staging technique in this patient, and made the differential diagnosis of the lymph node involvement from MMC and CLL possible.
Cervigón
Iván
I
Servicio Dermatología, Hospital Virgen de la Salud, Toledo, España. icervigon@sescam.jccm.es
Gargallo
Ana B
AB
Bahillo
Constanza
C
Martínez-Amo
José L
JL
Orradre
Juan L
JL
Muñoz-Madero
Vicente
V
García-Almagro
Domingo
D
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D015266:Carcinoma, Merkel Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D016867:Immunocompromised Host; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy / Q000276:immunology; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D049268:Positron-Emission Tomography; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014750:Vincristine / Q000009:adverse effects / Q000627:therapeutic use
D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone