title: Ureteral obstruction after dextranomer/hyaluronic acid copolymer injection for treatment of secondary vesicoureteral reflux after renal transplantation.
abstract: Ureteral obstruction after transurethral injection therapy for primary vesicoureteral reflux is known to occur in less than 1% of cases. We report the first case of a ureteral obstruction after transurethral injection of dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of secondary vesicoureteral reflux after renal transplantation. Loss of transplant function made reimplantation of the ureter necessary. A periureteral phlebitis and moderate foreign body reaction was found histologically, although the patient had received immunosuppressive therapy. Endoscopic therapy of secondary vesicoureteral reflux in patients after renal transplantation is a reasonable minimally invasive treatment option; however, severe complications may occur.
authors.affiliation: Department of Urology, University Hospital Basel, Basel, Switzerland. seiferth@uni-duesseldorf.de
authors.forename: Hans-Helge
authors.initials: HH
authors.lastname: Seifert
authors.forename: Brunello
authors.initials: B
authors.lastname: Mazzola
authors.forename: Tobias
authors.initials: T
authors.lastname: Zellweger
authors.forename: Robin
authors.initials: R
authors.lastname: Ruszat
authors.forename: Alexander
authors.initials: A
authors.lastname: Muller
authors.forename: Felix
authors.initials: F
authors.lastname: Burkhalter
authors.forename: Jörg
authors.initials: J
authors.lastname: Steiger
authors.forename: Tullio
authors.initials: T
authors.lastname: Sulser
authors.forename: Alexander
authors.initials: A
authors.lastname: Bachmann
mesh_terms: D003911:Dextrans / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005549:Foreign-Body Reaction / Q000150:complications* / Q000209:etiology; D006801:Humans; D007267:Injections; D016030:Kidney Transplantation; D008875:Middle Aged; D011183:Postoperative Complications; D019736:Prostheses and Implants / Q000009:adverse effects*; D014517:Ureteral Obstruction / Q000209:etiology*; D014718:Vesico-Ureteral Reflux / Q000628:therapy*
chemical_list: D003911:Dextrans; C013471:dextranomer