title: Multifocal osteosarcoma involving unusual sites.
abstract: We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and has a poor prognosis. The literature on 11 cases of MFOS with extraosseus, extrapulmonary involvement reported previously has been reviewed.
authors.affiliation: Department of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, India. mbhutani@mdanderson.org
authors.forename: Manisha
authors.initials: M
authors.lastname: Bhutani
authors.forename: Ashutosh Kumar
authors.initials: AK
authors.lastname: Pathak
authors.forename: Manju
authors.initials: M
authors.lastname: Sengar
authors.forename: S Datta
authors.initials: SD
authors.lastname: Gupta
authors.forename: Paresh
authors.initials: P
authors.lastname: Jain
authors.forename: Sanjay
authors.initials: S
authors.lastname: Thulkar
authors.forename: Vinod
authors.initials: V
authors.lastname: Kochupillai
mesh_terms: D000328:Adult; D000740:Anemia / Q000209:etiology / Q000503:physiopathology; D019046:Bone Marrow Neoplasms / Q000556:secondary; D001859:Bone Neoplasms / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D003389:Cranial Nerve Diseases / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D007938:Leukemia / Q000473:pathology; D008175:Lung Neoplasms / Q000556:secondary; D008223:Lymphoma / Q000473:pathology; D008297:Male; D012516:Osteosarcoma / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D020335:Paraparesis / Q000209:etiology / Q000503:physiopathology; D012512:Sarcoma, Ewing / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000556:secondary