Comorbidity of schizophrenia and cancer: clinical recommendations for treatment.
The paper analyzes some issues on the comorbidity between schizophrenia and cancer. Epidemiological studies have reported contradictory results, but it is certain that patients with schizophrenia are more likely to suffer from risk factors for cancer development, such as increased alcohol abuse, obesity, nicotine dependence and decreased physical activity. The paper gives guidelines for the treatment of cancer in patients with schizophrenia, and discusses possible interactions between chemotherapy and psychotropic drugs. Particular attention is paid to the use of antipsychotics which increase the level of prolactin, in view of the possible risk of breast and endometrial cancer in patients with schizophrenia.
Damjanović
Aleksandar
A
Institute for Psychiatry, Clinical Centre of Serbia, Belgrade, Serbia and Montenegro. salt@eunet.yu
Ivković
Maja
M
Jasović-Gasić
Miroslava
M
Paunović
Vladimir
V
D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002455:Cell Division / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D015897:Comorbidity; D004347:Drug Interactions; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D014150:Antipsychotic Agents