[Lymphocyte changes in ischemic heart disease].
The paper focuses on the membrane lipid complex status and lymphocyte metabolic activity in IHD patients to elaborate new approaches toward treatment and prevention of immune disorders in the above pathology. The study was made in blood specimens from 53 coronary patients presenting with progressive unstable angina. The diagnosis was made on the basis of a complex clinical-and-laboratory and electrocardiographic evaluation. The composition of the lymphocyte membrane lipid complex and blood serum was studied with the aid of the gas chromatography techniques. Three variants were identified of change in the lipid composition of lymphocyte membranes in IHD patients having undergone the above evaluation. We consider it expediant to use criteria for the state of lymphocyte membranes in IHD patients in order that we might properly deal with issues concerning diagnosis, prognosis and selection of optimum pathogenetic therapy of the medical condition in question.
Afonina
G B
GB
Oleĭnik
A Iu
AIu
Sorokina
I A
IA
Briuzgina
T S
TS
Rusin
E V
EV
D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000378:metabolism; D012313:RNA / Q000378:metabolism
D000975:Antioxidants; D008563:Membrane Lipids; D012313:RNA; D004247:DNA