title: Filipino version of the M. D. Anderson Symptom Inventory: validation and multisymptom measurement in cancer patients.
abstract: Assessing cancer-related symptoms requires a brief, reliable, valid, and culturally adapted symptom screening tool. In the Philippines, cancer patients (n=206) and community-dwelling adults (n=170) participated in a cross-sectional validation study of the Filipino version of the M. D. Anderson Symptom Inventory (MDASI-F). Both exploratory factor analysis and hierarchical cluster analysis revealed two underlying symptom severity constructs--general and gastrointestinal symptoms--consistent with the English, Japanese, and Chinese versions of the MDASI. Cronbach alpha coefficients of 0.79 and 0.77, respectively, demonstrated acceptable internal consistency for the two factors. Known-group validity was confirmed by significant differences on MDASI-F items by performance status (P<0.01 or P<0.001). Fatigue, sadness, distress, and pain were significant predictors of symptom interference. Cancer patients reported significantly greater symptom severity on multiple items than did the community sample. The MDASI-F is reliable and valid for evaluating cancer-related symptoms and their impact on Filipino cancer patients.
authors.affiliation: Department of Symptom Research (X.S.W., H.G., T.R.M., C.S.C.), Division of Internal Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. swong@mdanderson.org
authors.forename: Xin Shelley
authors.initials: XS
authors.lastname: Wang
authors.forename: Adriano V
authors.initials: AV
authors.lastname: Laudico
authors.forename: Hong
authors.initials: H
authors.lastname: Guo
authors.forename: Tito R
authors.initials: TR
authors.lastname: Mendoza
authors.forename: Maria Lourdes
authors.initials: ML
authors.lastname: Matsuda
authors.forename: Victor D
authors.initials: VD
authors.lastname: Yosuico
authors.forename: Edilberto P
authors.initials: EP
authors.lastname: Fragante
authors.forename: Charles S
authors.initials: CS
authors.lastname: Cleeland
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006306:Health Surveys; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010679:Philippines; D015203:Reproducibility of Results