title: [Intraocular pressure and corneal thickness. A comparison between non-contact tonometry and applanation tonometry].
abstract: OBJECTIVE
  Corneal thickness and deformation seem to have a considerable influence on intraocular pressure measurement. Due to differences in the corneal deformation in either non-contact tonometry or applanation tonometry, both methods should be compared in the same patient group depending on central corneal thickness.
  
  
  METHODS
  In 106 eyes of 55 patients (18 males, 37 females, age 17-89 years, mean 63.3 years) with glaucoma and central corneal thickness between 409 and 644 microm (Orbscan II pachymetry) intraocular pressure was measured in each eye with non-contact tonometry (Reichert AT550) and 30 min later with Goldman applanation tonometry.
  
  
  RESULTS
  Non-contact tonometry as well as applanation tonometry showed a positive correlation between measured intraocular pressure and corneal thickness. The steepness of the line of regression was 0.33 mmHg per 10 microm of corneal thickness in non-contact tonometry and 0.17 mmHg per 10 microm of corneal thickness in applanation tonometry.
  
  
  CONCLUSIONS
  Independently of the large differences in individual pressure measurements between non-contact tonometry and applanation tonometry, we found higher IOP values with non-contact tonometry in thicker corneas as compared with applanation tonometry. In thinner corneas there was a better correspondence between both methods. Thus, it seems very likely that corneal rigidity increases with corneal thickness.
authors.affiliation: Abteilung für Augenheilkunde, Klinikum Nord-Heidberg, Tangstedter Landstrasse 400, 22417 Hamburg. augen-klinikum-nord@gmx.de
authors.forename: N
authors.initials: N
authors.lastname: Domke
authors.forename: A
authors.initials: A
authors.lastname: Hager
authors.forename: W
authors.initials: W
authors.lastname: Wiegand
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000473:pathology / Q000503:physiopathology*; D019781:Corneal Topography / Q000379:methods*; D005260:Female; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014065:Tonometry, Ocular / Q000379:methods*