title: Effects of a behavioural intervention on quality of life and related variables in angioplasty patients: results of the EXhaustion Intervention Trial.
abstract: OBJECTIVE
  The EXhaustion Intervention Trial investigated the effect of a behavioural intervention programme on exhaustion, health-related quality of life (HRQL), depression, anxiety, hostility, and anginal complaints in angioplasty patients who felt exhausted after percutaneous coronary intervention (PCI).
  
  
  METHODS
  Seven hundred ten patients were randomized into an intervention group and a usual care control group. The group intervention focused on stressors leading to exhaustion and on support of recovery. HRQL (measured by the MacNew questionnaire), exhaustion [measured by the Maastricht Questionnaire and the Maastricht Interview Vital Exhaustion (MIVE)], anxiety (measured by the State-Trait Inventory), and depression (measured by the structured clinical interview for DSM-IV) were assessed at intake and at 6 and 18 months. Presence of anginal complaints was assessed at 18 months.
  
  
  RESULTS
  The intervention had a significant beneficial effect on all psychological factors except hostility and on the presence of anginal complaints. The effect of the intervention on exhaustion, as assessed by the MIVE, was modified by a previous history of coronary artery disease (CAD). Gender modified the effect of the intervention on exhaustion and on anxiety, the strongest effect being observed in women.
  
  
  CONCLUSIONS
  The behavioural intervention improved HRQL and related psychological factors. Somatic comorbidity and a history of CAD limited the effect of the intervention.
authors.affiliation: Department Medical Psychology, Maastricht University, Box 616, 6200 MD Maastricht, The Netherlands. ad.appels@mp.unimaas.nl
authors.forename: Ad
authors.initials: A
authors.lastname: Appels
authors.forename: Therese
authors.initials: T
authors.lastname: van Elderen
authors.forename: Frits
authors.initials: F
authors.lastname: Bär
authors.forename: Gerda
authors.initials: G
authors.lastname: van der Pol
authors.forename: Ruud A M
authors.initials: RA
authors.lastname: Erdman
authors.forename: Maarten
authors.initials: M
authors.lastname: Assman
authors.forename: Wim
authors.initials: W
authors.lastname: Trijsburg
authors.forename: Rob
authors.initials: R
authors.lastname: van Diest
authors.forename: Jan
authors.initials: J
authors.lastname: van Dixhoorn
authors.forename: Susanne S
authors.initials: SS
authors.lastname: Pedersen
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000523:psychology* / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000523:psychology*; D001007:Anxiety / Q000523:psychology* / Q000628:therapy*; D001521:Behavior Therapy; D003863:Depression / Q000523:psychology* / Q000628:therapy*; D005221:Fatigue / Q000523:psychology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006791:Hostility; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D011788:Quality of Life / Q000523:psychology*; D012803:Sick Role; D013315:Stress, Psychological / Q000150:complications; D011795:Surveys and Questionnaires