title: Recurrence of inflammatory pseudotumor in the distal bile duct: lessons learned from a single case and reported cases.
abstract: Inflammatory myofibroblastic tumors (IMTs) or inflammatory pseudotumors (IPs) have been extensively discussed in the literature. They are usually found in the lung and upper respiratory tract. However, reporting of cases involving the biliopancreatic region has increased over recent years. Immunohistochemical study of these lesions limited to the pancreatic head or distal bile duct seems to be compatible with those observed in a new entity called autoimmune pancreatitis, but usually intense fibrotic reaction (zonation) predominates producing a mass. When this condition is limited to the pancreatic head, the common bile duct might be involved by the inflammatory process and jaundice may occur often resembling adenocarcinoma of the pancreas. We have previously reported a case of IMT arising from the bile duct associated with autoimmune pancreatitis which is an extremely rare entity. Four years after Kaush-Whipple resection, radiological examination on routine follow-up revealed a tumor mass, suggesting local recurrence. Ultrasound-guided FNA confirmed our suspicious diagnosis. This present case, as others, suggests that persistent follow-up is necessary in order to prevent irreversible liver damage at this specific location.
authors.affiliation: Department of Gastrointestinal Surgery, University Hospital of Canary Islands, Ofra s/n. La Cuesta, La Laguna, Santa Cruz de Tenerife, Spain. drtomassetti@wanadoo.es
authors.forename: E M
authors.initials: EM
authors.lastname: Lopez-Tomassetti Fernandez
authors.forename: H Diaz
authors.initials: HD
authors.lastname: Luis
authors.forename: A Martin
authors.initials: AM
authors.lastname: Malagon
authors.forename: I Arteaga
authors.initials: IA
authors.lastname: Gonzalez
authors.forename: A Carrillo
authors.initials: AC
authors.lastname: Pallares
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010195:Pancreatitis / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D000305:Adrenal Cortex Hormones