title: Lipoma of the cerebellopontine angle.
abstract: Lipomas of the cerebellopontine angle (CPA) are unusual tumors that typically present with hearing loss, tinnitus, dizziness, and occasionally facial neuropathies. We describe the case of a healthy 42-year-old woman who presented with left-sided hearing loss and facial synkinesis. T1-weighted magnetic resonance imaging revealed an enhancing lesion of the left CPA with no signal on fat suppression sequences. Despite conservative therapy, the patient developed progressive hemifacial spasm, and a suboccipital craniotomy approach was used to debulk the tumor, which encased cranial nerves V, VII, VIII, IX, X, and XI. Surgical histopathology demonstrated mature adipocytes, consistent with lipoma. Two years after surgery, the patient remains free of facial nerve symptoms. Cerebellopontine angle lipomas are rare lesions of the skull base and are reliably diagnosed with T1-weighted and fat suppression magnetic resonance sequences, which we recommend in the routine radiologic workup of CPA tumors. Accurate preoperative diagnosis is crucial because most CPA lipomas should be managed conservatively. Partial surgical resection is indicated only to alleviate intractable cranial neuropathies or relieve brainstem compression.
authors.affiliation: Department of Otolaryngology, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Jacob R
authors.initials: JR
authors.lastname: Brodsky
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Smith
authors.forename: Scott
authors.initials: S
authors.lastname: Litofsky
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D002528:Cerebellar Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D002530:Cerebellopontine Angle / Q000601:surgery; D003399:Craniotomy; D005145:Face; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D019569:Hemifacial Spasm / Q000209:etiology; D006801:Humans; D008067:Lipoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D046608:Synkinesis / Q000209:etiology