title: Fluoropolymer-coated dacron versus PTFE grafts for femorofemoral crossover bypass: randomised trial.
abstract: OBJECTIVE
  To investigate whether patency of a thin walled 8 mm fluoropassivated Dacron graft was similar to that of a standard 8mm PTFE graft for femorofemoral crossover bypass surgery.
  
  
  METHODS
  A randomised multicentre clinical trial comparing two vascular grafts with participation of 10 departments of vascular surgery in Denmark, Sweden and Norway.
  
  
  METHODS
  198 patients were randomised to PTFE (n=107) or fluoropolymer-coated Dacron grafts (n=91), 63% underwent surgery for claudication, 27% for ischaemic rest pain and 10% for tissue loss. The median follow-up time was 24 months (IQR 19-26 months).
  
  
  RESULTS
  The primary patency rate of the two grafts was similar (log rank test: p=0.35). The primary patency rates (95% CI) for coated Dacron and PTFE grafts were 92% (86-98) and 94% (89-99) at 12 months and 87% (74-95) and 93% (87-99) at 24 months, respectively.
  
  
  CONCLUSIONS
  In patients with unilateral iliac artery disease not amenable to angioplasty, the femoral-femoral bypass is durable and effective. No difference in patency was found between the two graft materials (fluoropolymer coated Dacron and PTFE).
authors.affiliation: Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark. jonas@eiberg.org
authors.forename: J P
authors.initials: JP
authors.lastname: Eiberg
authors.forename: O
authors.initials: O
authors.lastname: Røder
authors.forename: M
authors.initials: M
authors.lastname: Stahl-Madsen
authors.forename: N
authors.initials: N
authors.lastname: Eldrup
authors.forename: P
authors.initials: P
authors.lastname: Qvarfordt
authors.forename: A
authors.initials: A
authors.lastname: Laursen
authors.forename: M
authors.initials: M
authors.lastname: Greve
authors.forename: T
authors.initials: T
authors.lastname: Flörenes
authors.forename: O M
authors.initials: OM
authors.lastname: Nielsen
authors.forename: C
authors.initials: C
authors.lastname: Seidelin
authors.forename: T
authors.initials: T
authors.lastname: Vestergaard-Andersen
authors.forename: T V
authors.initials: TV
authors.lastname: Schroeder
mesh_terms: D000368:Aged; D001807:Blood Vessel Prosthesis / Q000009:adverse effects; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D020099:Coated Materials, Biocompatible; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D005465:Fluorocarbon Polymers; D006083:Graft Occlusion, Vascular / Q000209:etiology; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery; D007511:Ischemia / Q000601:surgery; D007866:Leg / Q000098:blood supply; D008297:Male; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D012307:Risk Factors; D014654:Vascular Patency
chemical_list: D020099:Coated Materials, Biocompatible; D005465:Fluorocarbon Polymers; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene