title: Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease.
authors.affiliation: Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA.
authors.forename: Aryan M A
authors.initials: AM
authors.lastname: Namboodiri
authors.forename: John R
authors.initials: JR
authors.lastname: Moffett
authors.forename: Peethambaran
authors.initials: P
authors.lastname: Arun
authors.forename: Raji
authors.initials: R
authors.lastname: Mathew
authors.forename: Sreela
authors.initials: S
authors.lastname: Namboodiri
authors.forename: Asha
authors.initials: A
authors.lastname: Potti
authors.forename: Jeremy
authors.initials: J
authors.lastname: Hershfield
authors.forename: Batool
authors.initials: B
authors.lastname: Kirmani
authors.forename: David M
authors.initials: DM
authors.lastname: Jacobowitz
authors.forename: Chikkathur N
authors.initials: CN
authors.lastname: Madhavarao
mesh_terms: D000085:Acetates / Q000378:metabolism; D000123:Acetyltransferases / Q000235:genetics / Q000378:metabolism; D000581:Amidohydrolases / Q000235:genetics / Q000378:metabolism; D000818:Animals; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D017825:Canavan Disease / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D050356:Lipid Metabolism; D009186:Myelin Sheath / Q000737:chemistry / Q000378:metabolism
chemical_list: D000085:Acetates; D001224:Aspartic Acid; C000179:N-acetylaspartate; D000123:Acetyltransferases; C046791:aspartate N-acetyltransferase; D000581:Amidohydrolases; C019751:aspartoacylase