title: Hantavirus cardiopulmonary syndrome: immune response and pathogenesis.
abstract: Hantaviruses are emerging viruses in the Americas that cause cardiopulmonary syndrome with high lethality. The intense cellular immune response to hantavirus alters normal endothelial cell barrier functions and seems to be harmful to the host. On the other hand, the humoral immune response seems to be essential for recovery from infection.
authors.affiliation: Virology Research Center, School of Medicine of Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, Ribeirão Preto, São Paulo 14049-900, Brazil.
authors.forename: Alessandra A
authors.initials: AA
authors.lastname: Borges
authors.forename: Gelse M
authors.initials: GM
authors.lastname: Campos
authors.forename: Marcos L
authors.initials: ML
authors.lastname: Moreli
authors.forename: Ricardo L M
authors.initials: RL
authors.lastname: Souza
authors.forename: Victor H
authors.initials: VH
authors.lastname: Aquino
authors.forename: Fabiano P
authors.initials: FP
authors.lastname: Saggioro
authors.forename: Luiz T M
authors.initials: LT
authors.lastname: Figueiredo
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D006476:Orthohantavirus / Q000235:genetics / Q000276:immunology; D018804:Hantavirus Pulmonary Syndrome / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology / Q000821:virology; D006801:Humans; D007111:Immunity, Cellular; D008954:Models, Biological; D014766:Viremia
chemical_list: D000914:Antibodies, Viral