Fluoropolymer-coated dacron versus PTFE grafts for femorofemoral crossover bypass: randomised trial.
OBJECTIVE
To investigate whether patency of a thin walled 8 mm fluoropassivated Dacron graft was similar to that of a standard 8mm PTFE graft for femorofemoral crossover bypass surgery.


METHODS
A randomised multicentre clinical trial comparing two vascular grafts with participation of 10 departments of vascular surgery in Denmark, Sweden and Norway.


METHODS
198 patients were randomised to PTFE (n=107) or fluoropolymer-coated Dacron grafts (n=91), 63% underwent surgery for claudication, 27% for ischaemic rest pain and 10% for tissue loss. The median follow-up time was 24 months (IQR 19-26 months).


RESULTS
The primary patency rate of the two grafts was similar (log rank test: p=0.35). The primary patency rates (95% CI) for coated Dacron and PTFE grafts were 92% (86-98) and 94% (89-99) at 12 months and 87% (74-95) and 93% (87-99) at 24 months, respectively.


CONCLUSIONS
In patients with unilateral iliac artery disease not amenable to angioplasty, the femoral-femoral bypass is durable and effective. No difference in patency was found between the two graft materials (fluoropolymer coated Dacron and PTFE).
Eiberg
J P
JP
Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark. jonas@eiberg.org
Røder
O
O
Stahl-Madsen
M
M
Eldrup
N
N
Qvarfordt
P
P
Laursen
A
A
Greve
M
M
Flörenes
T
T
Nielsen
O M
OM
Seidelin
C
C
Vestergaard-Andersen
T
T
Schroeder
T V
TV
D000368:Aged; D001807:Blood Vessel Prosthesis / Q000009:adverse effects; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D020099:Coated Materials, Biocompatible; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D005465:Fluorocarbon Polymers; D006083:Graft Occlusion, Vascular / Q000209:etiology; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery; D007511:Ischemia / Q000601:surgery; D007866:Leg / Q000098:blood supply; D008297:Male; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D012307:Risk Factors; D014654:Vascular Patency
D020099:Coated Materials, Biocompatible; D005465:Fluorocarbon Polymers; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene