title: Plant signalling: the inexorable rise of auxin.
abstract: The flow of signalling molecules across a field of cells to generate a pattern that is then transduced into a differential response in those cells is a fundamental concept in developmental biology. Recent studies have identified a system that regulates the flux of the growth factor auxin through plant tissues via the subcellular asymmetric localization of specific transporters. The recurrent use of this auxin transport system in different developmental and physiological contexts reveals a fundamental mechanism underpinning organogenesis, stem cell positioning and the growth response of the plant to the environment. Here, I will discuss key advances in the identification of auxin transporters and their integration with auxin signal transduction pathways.
authors.affiliation: Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield, UK S10 2TN. a.fleming@sheffield.ac.uk
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Fleming
mesh_terms: D029681:Arabidopsis Proteins / Q000502:physiology; D018466:Gravity Sensing / Q000502:physiology; D007210:Indoleacetic Acids / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000502:physiology; D018519:Meristem / Q000166:cytology / Q000502:physiology; D063245:Plant Development; D010937:Plant Growth Regulators / Q000502:physiology*; D018520:Plant Shoots / Q000166:cytology / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; C493246:PLT1 protein, Arabidopsis; C493247:PLT2 protein, Arabidopsis; D010937:Plant Growth Regulators; D014157:Transcription Factors