Periodontal status in men with hypergonadotropic hypogonadism: effects of testosterone deficiency.
BACKGROUND
The purpose of this clinical study was to evaluate the possible influence of testosterone hormone on common clinical measurements of periodontal disease in men with hypergonadotropic hypogonadism.


METHODS
Twenty-four hypergonadotropic hypogonadal men (H) and 24 systemically healthy men (S) were divided into two groups as chronic periodontitis and clinically healthy controls after clinical examinations and radiographs. The H group consisted of 12 control (H/C) and 12 chronic periodontitis (H/P) patients, and the S group consisted of 12 control (S/C) and 12 chronic periodontitis (S/P) patients. Plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment loss (CAL) scores were recorded.


RESULTS
The mean of all clinical parameters (PI, GI, BOP, PD, and CAL) were significantly (P<0.05) higher in periodontitis groups (H/P and S/P) than controls (H/C and S/C). There were no significant differences in the PD and CAL scores between periodontitis groups (S/P and H/P). The mean of GI and BOP scores were statistically higher in the H/P group than the S/P group (P<0.05). There was a negative correlation between GI and free testosterone levels (r=-0.794; P<0.05).


CONCLUSIONS
According to these results, serum testosterone levels may possibly influence periodontal disease in men, and testosterone may have an inhibitory effect on gingival inflammation.
Daltaban
Ozlem
O
Faculty of Dentistry, Department of Periodontology, Gazi University, Ankara, Turkey.
Saygun
Işil
I
Bolu
Erol
E
D000328:Adult; D000704:Analysis of Variance; D016022:Case-Control Studies; D002908:Chronic Disease; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000150:complications*; D008297:Male; D010512:Periodontal Index; D010518:Periodontitis / Q000150:complications*; D018709:Statistics, Nonparametric; D013739:Testosterone / Q000097:blood / Q000172:deficiency* / Q000502:physiology
D013739:Testosterone