title: Genomewide evolutionary rates in laboratory and wild yeast.
abstract: As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated mutations in the lab. We report a low-to-intermediate rate of protein evolution in this strain relative to wild isolates.
authors.affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
authors.forename: James
authors.initials: J
authors.lastname: Ronald
authors.forename: Hua
authors.initials: H
authors.lastname: Tang
authors.forename: Rachel B
authors.initials: RB
authors.lastname: Brem
mesh_terms: D019143:Evolution, Molecular; D016681:Genome, Fungal; D009154:Mutation; D010802:Phylogeny; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D015003:Yeasts / Q000235:genetics*
chemical_list: D029701:Saccharomyces cerevisiae Proteins