[A man with the combination of dry and wet beriberi].
A 34-year-old alcoholic man had neurological and cardiac symptoms. The patient was admitted to the hospital for acute painful sensory disturbances and severe weakness of the feet. Neurological and electrophysiological investigation revealed axonal sensorimotor polyneuropathy that was most prominent in the legs. Cardiac assessment showed signs and symptoms of heart failure due to a high-output state. Blood analysis showed a low thiamine concentration of 58 nmol/l (lower reference limit: 80). Therefore, a diagnosis of combined wet beriberi with cardiomyopathy and dry beriberi with axonal polyneuropathy was made. The treatment of beriberi is simple and effective and consists of thiamine supplementation in conjunction with diuretic treatment. With this approach, the patient recovered fully. Patients with beriberi have a good prognosis, particularly when the diagnosis is made at an early stage.
Cox
F M E
FM
Medisch Centrum Alkmaar. f.cox@lumc.nl
Cornel
J H
JH
Aramideh
M
M
D000328:Adult; D020269:Alcoholic Neuropathy / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D000437:Alcoholism / Q000150:complications*; D001602:Beriberi / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002310:Cardiomyopathy, Alcoholic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D004232:Diuretics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011379:Prognosis; D013831:Thiamine / Q000097:blood / Q000627:therapeutic use*; D016896:Treatment Outcome
D004232:Diuretics; D013831:Thiamine