Is there a role of statins in the prevention of aortic biological prostheses degeneration.
It has been recently observed that statins might slow the progression of aortic stenosis or sclerosis. Preliminary reports suggested a similar positive effect in reducing the degeneration of aortic valve bioprostheses even though this hypothesis should be further proven and supported by new data. In this review the present evidences of the possible effects of statins in this field are discussed.
Antonini-Canterin
Francesco
F
Unità Operativa di Cardiologia, A.R.C. Azienda Ospedaliera S, Maria degli Angeli, Pordenone, Italy. cardiologia@aopn.fvg.it
Zuppiroli
Alfredo
A
Baldessin
Ferdinando
F
Popescu
Bogdan A
BA
Nicolosi
Gian Luigi
GL
D000818:Animals; D001024:Aortic Valve Stenosis / Q000209:etiology* / Q000517:prevention & control*; D050197:Atherosclerosis / Q000209:etiology* / Q000517:prevention & control*; D001705:Bioprosthesis / Q000009:adverse effects*; D019544:Equipment Failure Analysis; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D011475:Prosthesis Failure
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors