title: Synthesis of unique cagelike thiacalix[4]arene derivatives in a 1,3-alternate conformation.
abstract: A novel type of doubly bridged thiacalix[4]arenes in the 1,3-alternate conformation has been prepared by direct aminolysis reaction of easily accessible thiacalix[4]arene tetraacetates with alpha,omega-diamines. Despite the high excess of diamine, both sites of a 1,3-alternate conformer can be intramolecularly bridged to form the cagelike structures in high yields. Optimum results were obtained using 1,2-ethanediamine as bridging units. X-ray analysis of the novel cagelike molecules revealed a highly preorganized array of -C(O)-NH- bonds pointing to the interior of the cavity.
authors.affiliation: Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic.
authors.forename: Vaclav
authors.initials: V
authors.lastname: St'astný
authors.forename: Ivan
authors.initials: I
authors.lastname: Stibor
authors.forename: Ivana
authors.initials: I
authors.lastname: Císarová
authors.forename: Jan
authors.initials: J
authors.lastname: Sýkora
authors.forename: Michaela
authors.initials: M
authors.lastname: Pojarová
authors.forename: Pavel
authors.initials: P
authors.lastname: Lhoták