title: [The influence of intraoperative fluid therapy on the postoperative outcome in "fast track" colon surgery].
abstract: OBJECTIVE
  To evaluate the association between the intraoperative and postoperative application of different quantities of fluids and the incidence of postoperative complications after "fast-track"-colonic surgery.
  
  
  METHODS
  We performed a retrospective analysis of 136 patients undergoing elective "fast-track" colonic surgery (sigma resection and right hemicolectomy). Data collection in regard of fluid administration during surgery and in the post anaesthesia care unit (PACU) was based on anaesthesia charts and a prospectively generated surgery database. Classification into three volume groups (up to 3500 ml = group 1, 3500 - 5500 ml = group 2, more than 5500 ml = group 3). Basic patient characteristics, pre-existing conditions, type and duration of surgery and anastomoses were documented. We analysed the incidence of postoperative complications such as wound infections, anastomotic leak, bleeding, bowel obstruction, cardiovascular failure, hypertension, pulmonary failure, pneumonia, renal failure, urinary tract infection, neurological and psychiatric complications in the different volume groups.
  
  
  RESULTS
  115 patients were infused with up to 3500 mLs of fluids, 19 patients received more than 3500 mLs, two patients were infused with 6000 ml and 7500 mLs, respectively. This was in median 36 ml/kg in the restrictive and 53 ml/kg in the higher volume groups (group 2 and 3 together), respectively. The duration of surgery and anaesthesia was significantly different between both fluid groups (p = 0,023). In a logistic regression model only intraoperative blood loss was independently associated with the volume of infused fluid (OR 0,393, 95 % CI 1.028 - 2.306, p < 0.01). The rate of postoperative complications was not different between groups (p = 0,228).
  
  
  CONCLUSIONS
  The incidence of postoperative complications was not different between patients who were infused 36 ml/kg or 53 ml/kg of fluids during surgery and post anaesthesia care unit stay.
authors.affiliation: Klinik für Anästhesiologie und operative Intensivmedizin, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Berlin. christian.von_heyman@charite.de
authors.forename: C
authors.initials: C
authors.lastname: von Heymann
authors.forename: D
authors.initials: D
authors.lastname: Grebe
authors.forename: W
authors.initials: W
authors.lastname: Schwenk
authors.forename: M
authors.initials: M
authors.lastname: Sander
authors.forename: M
authors.initials: M
authors.lastname: Hensel
authors.forename: J M
authors.initials: JM
authors.lastname: Müller
authors.forename: C
authors.initials: C
authors.lastname: Spies
mesh_terms: D000368:Aged; D003082:Colectomy; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D012189:Retrospective Studies; D016896:Treatment Outcome