title: Prevalence of left ventricular hypertrophy in persons with and without obstructive sleep apnea.
abstract: We investigated the prevalence of left ventricular hypertrophy (LVH) in persons with and without obstructive sleep apnea (OSA). Fifty-three persons had a nocturnal polysomnogram to diagnose OSA and 2-dimensional echocardiograms to measure left ventricular mass. OSA was considered mild if the respiratory disturbance index (RDI) was 5 to 15, moderate if the RDI was 15 to 30, and severe if the RDI was >30. LVH was diagnosed if the left ventricular mass index was >110 g/m in women and >134 g/m in men. LVH was present in 21 of 27 persons (78%) with moderate or severe OSA, in 6 of 13 persons (46%) with mild OSA, and in 3 of 13 persons (23%) with no OSA (P < 0.001 comparing moderate or severe OSA with no OSA and P < 0.05 comparing moderate or severe OSA with mild OSA). OSA was a significant independent predictor of LVH after controlling the confounding effects of hypertension with an odds ratio of 3.579 (95% confidence interval, 1.589-8.058).
authors.affiliation: Department of Medicine, Division of Pulmonary/Critical Care, Westchester Medical Center/New York Medical College, Valhalla, New York 10595, USA.
authors.forename: Rishi
authors.initials: R
authors.lastname: Sukhija
authors.forename: Wilbert S
authors.initials: WS
authors.lastname: Aronow
authors.forename: Rasham
authors.initials: R
authors.lastname: Sandhu
authors.forename: Priyanka
authors.initials: P
authors.lastname: Kakar
authors.forename: George P
authors.initials: GP
authors.lastname: Maguire
authors.forename: Chul
authors.initials: C
authors.lastname: Ahn
authors.forename: Stuart G
authors.initials: SG
authors.lastname: Lehrman
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000453:epidemiology