title: Macrophage activation syndrome.
abstract: Macrophage Activation Syndrome is a rare and potentially fatal disease, to be considered in patients with a SIRS like clinical presentation. Falling ESR and hyperferritinemia in the appropriate clinical setting can be the greatest clues. We report a case in which a female admitted with fever and rash, initially had systemic inflammatory response syndrome (SIRS) like clinical presentation, but eventually proved to be a rare case of fatal Macrophage Activation Syndrome.
authors.affiliation: Department of Internal Medicine, Medical College Hospital, Trivandrum.
authors.forename: M K
authors.initials: MK
authors.lastname: Kumar
authors.forename: M K
authors.initials: MK
authors.lastname: Suresh
authors.forename: D
authors.initials: D
authors.lastname: Dalus
mesh_terms: D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000209:etiology; D008262:Macrophage Activation; D008875:Middle Aged; D010198:Pancytopenia / Q000209:etiology; D013163:Splenomegaly / Q000209:etiology; D013577:Syndrome; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis*