title: Drug-induced nail diseases.
abstract: Although many nail disorders have been associated with drug intake, most reports are anecdotal. Most nail changes caused by drugs are the outcome of acute toxicity to the nail epithelia; nail symptoms depend on which nail structure is damaged. The most com-mon symptoms include Beau's lines/onychomadesis, melanonychia, onycholysis, and periungual pyogenic granulomas. Drug-induced nail abnormalities are usually transitory and disappear with drug withdrawal, but sometimes persist over time. This article reviews drugs that have been consistently associated with nail abnormalities.
authors.affiliation: Department of Dermatology, University of Bologna, Via Massarenti, 1-40138 Bologna, Italy. bmpiracc@med.unibo.it
authors.forename: Bianca Maria
authors.initials: BM
authors.lastname: Piraccini
authors.forename: Matilde
authors.initials: M
authors.lastname: Iorizzo
authors.forename: Michela
authors.initials: M
authors.lastname: Starace
authors.forename: Antonella
authors.initials: A
authors.lastname: Tosti
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects; D044966:Anti-Retroviral Agents / Q000009:adverse effects; D000925:Anticoagulants / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D000962:Antimalarials / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D006801:Humans; D019216:Metals, Heavy / Q000009:adverse effects; D009260:Nail Diseases / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D012176:Retinoids / Q000009:adverse effects
chemical_list: D000319:Adrenergic beta-Antagonists; D044966:Anti-Retroviral Agents; D000925:Anticoagulants; D000927:Anticonvulsants; D000962:Antimalarials; D000970:Antineoplastic Agents; D019216:Metals, Heavy; D012176:Retinoids