Evaluation of hepatic function after orthotopic liver transplantation: a comparative study using Belzer and Collins solutions.
Belzer and Collins are solutions used in liver transplantation. The purpose of this study was to compare liver function after utilization of two different schemes of graft preservation using both solutions. Between December 2004 and September 2005, 43 liver transplantations were performed. Twenty-three of these used 2 L of Collins solution and 2 L of Belzer solution as the preservation solution. The others used three L of Collins and 1 L of Belzer solution as the preservation solution. The cold ischemia time of both groups was similar. We analyzed liver function using the serum ALT, AST, bilirubin and international normalized ratio. On the first day after the transplantation, the level of international normalized ratio of the group of patients that used 1 L of Belzer was significantly higher than the other group (P<.05). The levels of ALT, AST, and bilirubin were not different on day 7 after transplantation. We concluded that using only 1 L of Belzer solution is as efficient with the advantage that it is less expensive.
Garcia
J H P
JH
The Centro de Transplante de Fígado do Ceará, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Brazil.
Barros
M A P
MA
Gonçalves
B P A
BP
Garcia
D S
DS
Costa
P E G
PE
Coelho
G R
GR
Borges
G C
GC
Fernandes
C R
CR
Viana
C F G
CF
Vasconcelos
J B M
JB
D000241:Adenosine; D000328:Adult; D000493:Allopurinol; D005260:Female; D005978:Glutathione; D006801:Humans; D006982:Hypertonic Solutions; D007328:Insulin; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D019188:Organ Preservation Solutions; D011887:Raffinose
C024102:Collins' solution; D006982:Hypertonic Solutions; D007328:Insulin; D019188:Organ Preservation Solutions; C055206:University of Wisconsin-lactobionate solution; D000493:Allopurinol; D005978:Glutathione; D000241:Adenosine; D011887:Raffinose