title: Treatment of pediatric suppurative mastoiditis: is peripherally inserted central catheter (PICC) antibiotic therapy necessary?
abstract: OBJECTIVE
  A review of the treatment of pediatric acute mastoiditis requiring surgical intervention managed with and without PICC therapy postoperatively.
  
  
  METHODS
  Retrospective study of 42 cases from 1989 to 2004 treated at a regional children's hospital.
  
  
  RESULTS
  Sixteen patients received postoperative PICC therapy and 26 received a course of oral antibiotics. The PICC group received on average 12.12 days of intravenous antibiotics compared to only 3.53 days for the non-PICC group (P < 0.001). No differences were observed between the two groups in treatment outcomes. One patient from each group required rehospitalization. One minor complication was experienced in a patient in the PICC group. There were no surgical complications. The total cost for outpatient PICC therapy increased treatment costs by approximately $1500 to $2500.
  
  
  CONCLUSIONS
  Oral antibiotic therapy is sufficient after surgical intervention for acute pediatric suppurative mastoiditis without intracranial complications and does not result in adverse treatment outcome.
  
  
  CONCLUSIONS
  Use of PICC therapy after surgical intervention for mastoiditis should be limited.
  
  
  METHODS
  B-3b.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Kansas School of Medicine, Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Moore
authors.forename: Julie L
authors.initials: JL
authors.lastname: Wei
authors.forename: Holly J
authors.initials: HJ
authors.lastname: Smith
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Mayo
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000191:economics; D002406:Catheterization, Peripheral; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008417:Mastoiditis / Q000188:drug therapy* / Q000601:surgery; D011182:Postoperative Care; D012189:Retrospective Studies; D013492:Suppuration / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents