Genetic Map of Bacteriophage phiX174.
Bacteriophage phiX174 temperature-sensitive and nonsense mutations in eight cistrons were mapped by using two-, three-, and four-factor genetic crosses. The genetic map is circular with a total length of 24 x 10(-4)wt recombinants per progeny phage. The cistron order is D-E-F-G-H-A-B-C. High negative interference is seen, consistent with a small closed circular deoxyribonucleic acid molecule as a genome.
Benbow
R M
RM
Division of Biology, California Institute of Technology, Pasadena, California 91109.
Hutchison
C A
CA
Fabricant
J D
JD
Sinsheimer
R L
RL