title: Cognitive impairment and carotid atherosclerosis in a general Italian midlife and old population.
abstract: The authors describe the design and the general, ultrasonographic, neuropsychological methodology of an observational epidemiological population survey, named REMEMBER (Registry Evaluation Memory in Buttrio e Remanzacco) conducted in the northeast of Italy in a randomized stratified sample of 1,026 subjects (554 F and 472 M) aged 55-98 years. The study was planned as cross-sectional and longitudinal survey of cognitive impairment, cardiovascular risk factors, carotid atherosclerosis in a midlife and older Italian population sample. The objectives of the first phase are to assess the prevalence of the different types of dementia, the cognitive impairment non-dementia, the cardiovascular risk factors, the carotid intima-media thickness and arterial distensibility, and of depression. The conclusions of this study will make it possible to organize preventive and interventional strategies for these epidemic conditions.
authors.affiliation: Department of Neurology, Gervasutta Hospital, Udine, Italy. patrizio.prati@tin.it
authors.forename: P
authors.initials: P
authors.lastname: Prati
authors.forename: M
authors.initials: M
authors.lastname: Casaroli
authors.forename: A
authors.initials: A
authors.lastname: Bignamini
authors.forename: S
authors.initials: S
authors.lastname: Scotti
authors.forename: L
authors.initials: L
authors.lastname: Canciani
authors.forename: M
authors.initials: M
authors.lastname: Ruscio
authors.forename: M
authors.initials: M
authors.lastname: Balestrieri
authors.forename: N
authors.initials: N
authors.lastname: Bornstein
authors.forename: O
authors.initials: O
authors.lastname: Zanetti
authors.forename: A
authors.initials: A
authors.lastname: Tosetto
authors.forename: S
authors.initials: S
authors.lastname: Castellani
authors.forename: L
authors.initials: L
authors.lastname: Pantoni
authors.forename: P J
authors.initials: PJ
authors.lastname: Touboul
authors.forename: D
authors.initials: D
authors.lastname: Inzitari
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000453:epidemiology*; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003072:Cognition Disorders / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014463:Ultrasonography