title: A batch chemiluminescence determination of enoxacin using a tris-(1,10-phenanthroline)ruthenium(II)-cerium(IV) system.
abstract: A batch type chemiluminescence (CL) determination of enoxacin is described. In this work, it was observed that enoxacin could enhance the chemiluminescence (CL) emission Ru(phen)3(2+)-Ce(IV) system and this enhancement effect was dependent on the concentration of enoxacin, based on which, CL system was established for the determination of enoxacin. Under the optimum experimental conditions, the linear range and detection limit are 0.6406-64.06 microg/ml and 0.0210 microg/ml, respectively. The R.S.D. is 1.75%. (n = 10). The proposed method has been applied to detect the content of enoxacin in pharmaceutical formulation and human serum with satisfactory results. The possible mechanism of the CL reaction was discussed.
authors.affiliation: Department of Chemistry, Kyungpook National University, Taegu 702-701, South Korea.
authors.forename: Mohammad Mainul
authors.initials: MM
authors.lastname: Karim
authors.forename: Sang Hak
authors.initials: SH
authors.lastname: Lee
authors.forename: Hyun Sook
authors.initials: HS
authors.lastname: Lee
authors.forename: Zun Ung
authors.initials: ZU
authors.lastname: Bae
authors.forename: Kyoung Hye
authors.initials: KH
authors.lastname: Choi
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis* / Q000737:chemistry; D002563:Cerium / Q000737:chemistry*; D015365:Enoxacin / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D007700:Kinetics; D008163:Luminescent Measurements; D015394:Molecular Structure; D010618:Phenanthrolines / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013464:Sulfuric Acids / Q000737:chemistry; D013607:Tablets
chemical_list: D000890:Anti-Infective Agents; D010618:Phenanthrolines; D013464:Sulfuric Acids; D013607:Tablets; D002563:Cerium; D015365:Enoxacin; D012428:Ruthenium; C033158:sulfuric acid