[Bezafibrate alone is an effective first-line therapy for primary sclerosing cholangitis: a case report].
The patient was a 58-year-old female. Though she had been in good health, increased hepatobiliary enzymes were detected in a health examination. She visited our hospital for close examination. The serum IgG4 level was normal, but ERCP and MRCP showed band-like stricture and beaded appearance of the bile ducts. A diagnosis of primary sclerosing cholangitis (PSC) was made. Since hyperlipidemia was also observed, oral administration of bezafibrate (400mg/day) alone was performed as the initial treatment, and transaminase, ALP, and GGT rapidly decreased. These results suggested that the initial administration of bezafibrate alone is effective against PSC.
Gondoh
Kazuhisa
K
Gondoh Medical Clinic.
Ono
Tetsujiro
T
Miyakoda
Kenji
K
Mukasa
Michita
M
So
Atsushi
A
Imamura
Kenichiro
K
Sata
Michio
M
D000284:Administration, Oral; D001629:Bezafibrate / Q000008:administration & dosage*; D015209:Cholangitis, Sclerosing / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D008875:Middle Aged
D000960:Hypolipidemic Agents; D001629:Bezafibrate