[Venous thromboembolism in patients with cancer].
The association between neoplastic diseases and venous thromboembolism (VTE) is known since long time ago. The nature of this association is bidirectional. On one hand, cancer increases the incidence of venous thrombosis and, on the other hand, the hemostatic system does play a key role in the tumorigenesis process. However, despite recent advances in the field, prophylaxis and treatment of VTE in cancer patients is still a challenge, due to the complexity of this type of patients. This review is focused on some important points regarding management of VTE in cancer patients such as physiopathology, epidemiology, search for hidden malignancy, prognostic impact, prophylaxis in the medical and surgical setting, or initial and long-term treatment.
Lecumberri
Ramón
R
Servicio de Hematología y Hemoterapia, Clínica Universitaria de Navarra, Facultad de Medicina, Universidad de Navarra, Pamplona, Navarra, España.
Feliu
Jesús
J
Rocha
Eduardo
E
D000925:Anticoagulants; D000970:Antineoplastic Agents; D006801:Humans; D019934:International Normalized Ratio; D009369:Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D012307:Risk Factors; D020246:Venous Thrombosis / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy
D000925:Anticoagulants; D000970:Antineoplastic Agents