Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix.
BACKGROUND
Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare.


METHODS
We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy.


CONCLUSIONS
Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient.
Maheshwari
Amita
A
Gynaecologic Oncology Service, Department of Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India.
Gupta
Sudeep
S
Shet
Tanuja
T
Wuntkal
Rekha
R
Tongaonkar
Hemant B
HB