title: Novel and selective palladium-catalyzed annulations of 2-alkynylphenols to form 2-substituted 3-halobenzo[b]furans.
abstract: [reaction: see text] A novel and selective palladium-catalyzed annulation of 2-alkynylphenols method for the synthesis of 2-substituted 3-halobenzo[b]furans is presented. In the presence of PdX(2), CuX(2), and HEt(3)NX, 2-substituted 3-halobenzo[b]furans were selectively obtained as the major products. The mechanism of the reaction was also discussed.
authors.affiliation: Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, People's Republic of China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Liang
authors.forename: Shi
authors.initials: S
authors.lastname: Tang
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Zhang
authors.forename: Li-Qiu
authors.initials: LQ
authors.lastname: Mao
authors.forename: Ye-Xiang
authors.initials: YX
authors.lastname: Xie
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li