Multifocal osteosarcoma involving unusual sites.
We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and has a poor prognosis. The literature on 11 cases of MFOS with extraosseus, extrapulmonary involvement reported previously has been reviewed.
Bhutani
Manisha
M
Department of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, India. mbhutani@mdanderson.org
Pathak
Ashutosh Kumar
AK
Sengar
Manju
M
Gupta
S Datta
SD
Jain
Paresh
P
Thulkar
Sanjay
S
Kochupillai
Vinod
V
D000328:Adult; D000740:Anemia / Q000209:etiology / Q000503:physiopathology; D019046:Bone Marrow Neoplasms / Q000556:secondary; D001859:Bone Neoplasms / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D003389:Cranial Nerve Diseases / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D007938:Leukemia / Q000473:pathology; D008175:Lung Neoplasms / Q000556:secondary; D008223:Lymphoma / Q000473:pathology; D008297:Male; D012516:Osteosarcoma / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D020335:Paraparesis / Q000209:etiology / Q000503:physiopathology; D012512:Sarcoma, Ewing / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000556:secondary