title: Nicotine gum withdrawal and migraine headaches.
abstract: Some abstinent smokers develop withdrawal symptoms when they stop using nicotine gum or when placebo is substituted. The present report describes a patient who suffered from severe migraine headaches after sudden discontinuation of nicotine gum. It has been suggested that physical dependence may be a cause of behavioral dependence on nicotine gum. Physicians should emphasize the need for gradual reduction of nicotine gum.
authors.affiliation: Department of Emergency Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel. darvasi@md.huji.ac.il
authors.forename: Ruth
authors.initials: R
authors.lastname: Stalnikowicz
mesh_terms: D000697:Central Nervous System Stimulants / Q000009:adverse effects* / Q000627:therapeutic use; D002638:Chewing Gum; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000209:etiology*; D009538:Nicotine / Q000009:adverse effects* / Q000627:therapeutic use; D016540:Smoking Cessation; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
chemical_list: D000697:Central Nervous System Stimulants; D002638:Chewing Gum; D009538:Nicotine