Characterization of pentasaccharide glycosides from the roots of Ipomoea arborescens.
Ten new pentasaccharide glycosides, arboresins 1-6 (1-6) and murucins 6-9 (8-11), along with five known glycolipids, were isolated from the roots of Ipomoea arborescens, and their structures were elucidated by spectroscopic and chemical methods. Compounds 1-6 and 8-11 were evaluated for cytotoxicity against a small panel of cancer cell lines.
León
Ismael
I
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa 62209 Cuernavaca, Morelos, México. ismaelr@ciq.uaem.mx
Mirón
Gumersindo
G
Alonso
Daniel
D
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006017:Glycolipids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D027741:Ipomoea / Q000737:chemistry*; D008800:Mexico; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D006017:Glycolipids; D006027:Glycosides