title: [Spindle-cell carcinoma in situ treated with 5% imiquimod].
abstract: We present the case of a 70-year-old woman with no personal history of interest who presented to her physician with a plaque in the right infraumbilical region whose largest diameter measured nine centimeters. The clinical and histological diagnosis was Bowen's disease. She was treated with 5 % imiquimod cream, once a day, four times a week, for eight weeks, with an excellent response. One year after treatment, no new lesions have appeared in the treated area.
authors.affiliation: Servicio de Dermatología y Venereología, Complejo Universitario Carlos Haya, Málaga, España. silvestremg@eresmas.net
authors.forename: Silvestre
authors.initials: S
authors.lastname: Martínez
authors.forename: Javier
authors.initials: J
authors.lastname: del Boz
authors.forename: Angel
authors.initials: A
authors.lastname: Vera
authors.forename: Andrés
authors.initials: A
authors.lastname: Sanz
authors.forename: Vicente
authors.initials: V
authors.lastname: Crespo
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001913:Bowen's Disease / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D000077271:Imiquimod; D009824:Ointments; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D009824:Ointments; D000077271:Imiquimod