Extinction of a saccharin-lithium association: assessment by consumption and taste reactivity.
Extinction of a conditioned palatability shift preceded extinction of conditioned taste avoidance whether rats were tested using a within-subjects design or a between-subjects design. In each of two experiments, consumption of 0.1% saccharin was paired with either 20 ml/kg of 0.15 M LiCl or equi-volume physiological saline on a single trial. In Experiment 1, on each of 10 extinction trials, rats were given a taste reactivity test immediately prior to a consumption test. In Experiment 2, half of the rats were extinguished by taste reactivity testing and half of the rats were extinguished by a consumption test on each of 10 extinction trials. In both experiments, the aversive reactions of gaping and passive dripping were extinguished in a single trial and the suppression of ingestive reactions was extinguished in 2 trials; however, extinction of taste avoidance required 4-5 trials. These results suggest that rats continue to avoid a lithium-paired flavor even when they do not have an aversion to the taste.
Cantora
Raúl
R
Universidad de Oviedo, Oviedo, Spain.
López
Matías
M
Aguado
Luis
L
Rana
Shadna
S
Parker
Linda A
LA
D000818:Animals; D003213:Conditioning, Psychological; D004791:Enzyme Inhibitors / Q000008:administration & dosage; D005108:Extinction, Psychological; D016651:Lithium Carbonate / Q000008:administration & dosage; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012439:Saccharin / Q000008:administration & dosage; D013649:Taste
D004791:Enzyme Inhibitors; D016651:Lithium Carbonate; D012439:Saccharin