How Rho exerts its muscle on RNA.
Rho factor in bacteria terminates transcription by using energy from ATP hydrolysis to forcefully dissociate the transcripts from RNA polymerase. used data from presteady-state ATPase kinetics to support a rational mechanistic model for Rho's action on RNA.
Richardson
John P
JP
Department of Chemistry, Indiana University, Bloomington, Indiana 47408. Electronic address: richardj@indiana.edu.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D006868:Hydrolysis; D012329:RNA, Bacterial / Q000378:metabolism*; D012234:Rho Factor / Q000378:metabolism*; D013728:Terminator Regions, Genetic / Q000502:physiology; D014158:Transcription, Genetic / Q000502:physiology*
D012329:RNA, Bacterial; D012234:Rho Factor; D000255:Adenosine Triphosphate; D012321:DNA-Directed RNA Polymerases; D000251:Adenosine Triphosphatases