[Possible mechanism and physiopathological significance of superoxide dismutase regulation by oxygen free radicals].
Possible mechanism of regulation of Cu,Zn-superoxide dismutase activity by oxygen free radicals is considered. It consists in the increase of dissociation of aggregated forms of this enzyme. The increase of specific activity may have pathophysiological importance under conditions of oxidative stress.
Miliakova
M N
MN
Shabanov
V V
VV
D000818:Animals; D004285:Dogs; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D018384:Oxidative Stress; D010179:Pancreas / Q000201:enzymology; D010777:Photochemistry; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
D013481:Superoxides; D013482:Superoxide Dismutase