Advances in diagnosis and therapy of childhood tuberculosis.
Tuberculosis remains a major health problem worldwide. Recently developed diagnostic blood tests may supplant or supplement TB skin test in some settings. Emergence of drug-resistant strains remains a global concern. New anti-tuberculous agents are being developed and are greatly needed. There is mounting evidence that BCG has significant effectiveness in prevention, but development of improved vaccines for tuberculosis should remain a priority.
Woods
Charles R
CR
Winston-Salem, North Carolina, USA. cwoods@wfubmc.edu
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000942:Antigens, Bacterial / Q000032:analysis*; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000627:therapeutic use*; D002648:Child; D004269:DNA, Bacterial / Q000032:analysis*; D003937:Diagnosis, Differential; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D016896:Treatment Outcome; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control
D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D000995:Antitubercular Agents; D001500:BCG Vaccine; D004269:DNA, Bacterial