Chemo-differentiating MCRs based on alpha-ketoesters and terminal alkynoates. A homoaldol-based ABB' system.
A novel ABB' 3 component reaction (3-CR) system based on the organocatalyzed homoaldolic condensation of alpha-ketoesters in the presence of terminal conjugated alkynoates is described.
Tejedor
David
D
Instituto de Productos Naturales y Agrobiología, CSIC, Astrofísico Francisco Sánchez 3, 38206 La Laguna, Tenerife, Canary Islands, Spain.
Santos-Expósito
Alicia
A
García-Tellado
Fernando
F
D000447:Aldehydes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D005021:Ethylamines / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D011422:Propionates / Q000737:chemistry
D000447:Aldehydes; D000480:Alkynes; D004952:Esters; D005021:Ethylamines; D007659:Ketones; D011422:Propionates; C116609:3-hydroxybutanal; C011537:propiolic acid; C016162:triethylamine