title: Control of pesticide residues by liquid chromatography-mass spectrometry to ensure food safety.
abstract: Liquid chromatography-mass spectrometry (LC-MS) has become an invaluable technique for the control of pesticide residues to ensure food safety. After an introduction about the regulations that highlights its importance to meet the official requirements on analytical performance, the different mass spectrometers used in this field of research, as well as the LC-MS interfaces and the difficulties associated with quantitative LC-MS determination, are discussed. The ability to use practical data for quantifying pesticides together with the option of obtaining structural information to identify target and non-target parent compounds and metabolites are discussed. Special attention is paid to the impact of sample preparation and chromatography on the ionization efficiency of pesticides from food. The last section is devoted to applications from a food safety point of view. (c) 2006 Wiley Periodicals, Inc.
authors.affiliation: Laboratori de Bromatologia i Toxicologia, Facultat de Farmàcia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, València, Spain. Yolanda.Pico@uv.es
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Picó
authors.forename: Guillermina
authors.initials: G
authors.lastname: Font
authors.forename: María José
authors.initials: MJ
authors.lastname: Ruiz
authors.forename: Mónica
authors.initials: M
authors.lastname: Fernández
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003257:Consumer Product Safety; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*; D010575:Pesticides / Q000032:analysis*; D012680:Sensitivity and Specificity
chemical_list: D010575:Pesticides