title: [Pulmonary vein antrum isolation guided by 3-D mapping system in 100 patients with chronic atrial fibrillation].
abstract: OBJECTIVE
  To investigate the efficacy and safety of circumferential pulmonary vein (PV) linear ablation (CPVA) guided by 3-D mapping system in patients with chronic atrial fibrillation (CAF).
  
  
  METHODS
  From August 2004 to November 2005, 100 consecutive patients with CAF were admitted to undergo CPVA guided by CARTO system and EnSite NavX system, the main procedure end point is electrical isolation of PVs. Success was defined as atrial tachyarrhythmia free without any antiarrhythmia drugs for at least 3 months. Clinical and procedural variables were collected, ANOVA analysis was employed to identify the risk factors predicting recurrence, P < 0.05 was considered significant.
  
  
  RESULTS
  After a mean of 9.7 +/- 5.7 months follow up, 70% (70/100) of patients freed from AF. ANOVA analysis identified isthmus ablation and poor left ventricular ejection fraction as the independent factors predicting success. Complications including pericardial tamponade (3 cases, 3%), stroke (1 case, 1%), asymptomatic pulmonary vein stenosis (2 cases, 2%).
  
  
  CONCLUSIONS
  CPVA guided by 3-D mapping system can be performed in CAF patients with an acceptable efficacy, but safety need to be improved.
authors.affiliation: Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China. chshma@vip.sina.com
authors.forename: Chang-sheng
authors.initials: CS
authors.lastname: Ma
authors.forename: Xu
authors.initials: X
authors.lastname: Liu
authors.forename: Jian-zeng
authors.initials: JZ
authors.lastname: Dong
authors.forename: Rong-hui
authors.initials: RH
authors.lastname: Yu
authors.forename: Xin-hua
authors.initials: XH
authors.lastname: Wang
authors.forename: Xing-peng
authors.initials: XP
authors.lastname: Liu
authors.forename: Hai-feng
authors.initials: HF
authors.lastname: Shi
authors.forename: De-yong
authors.initials: DY
authors.lastname: Long
authors.forename: Dong-ping
authors.initials: DP
authors.lastname: Fang
authors.forename: Fu-li
authors.initials: FL
authors.lastname: Hu
authors.forename: Ri-bo
authors.initials: RB
authors.lastname: Tang
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001281:Atrial Fibrillation / Q000628:therapy*; D017115:Catheter Ablation / Q000379:methods*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011667:Pulmonary Veins; D016896:Treatment Outcome