A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.
Lundwall
Ake
A
Lund University, Clinical Chemistry, Department of Laboratory Medicine, University Hospital MAS, S-205 02 Malmö, Sweden. ake.lundwall@med.lu.se
Band
Vimla
V
Blaber
Michael
M
Clements
Judith A
JA
Courty
Yves
Y
Diamandis
Eleftherios P
EP
Fritz
Hans
H
Lilja
Hans
H
Malm
Johan
J
Maltais
Lois J
LJ
Olsson
A Yvonne
AY
Petraki
Constantina
C
Scorilas
Andreas
A
Sotiropoulou
Georgia
G
Stenman
Ulf-Håkan
UH
Stephan
Carsten
C
Talieri
Maroulio
M
Yousef
George M
GM
D002888:Chromosomes, Human, Pair 19; D006801:Humans; D017385:Sequence Homology; D012697:Serine Endopeptidases / Q000235:genetics; D009626:Terminology as Topic; D020840:Tissue Kallikreins / Q000235:genetics
D012697:Serine Endopeptidases; D020840:Tissue Kallikreins