title: Modeling the heat transfer problem for the novel combined cryosurgery and hyperthermia system.
abstract: A multidimensional, finite element analysis (FEA) for the freezing, holding, rewarming and heating processes of biological tissues during the cryosurgery process of the new Combined Cryosurgery/Hyperthermia System is presented to theoretically test its validity. The tissues are treated as nonideal materials freezing over a temperature range, and the thermophysical properties of which are temperature dependent. The enthalpy method is applied to solve the highly nonlinear problem. It was found that when the same boundary condition and the same target tissue presented, the novel Cryosurgery/Hyperthermia System could supply the target tissue an approximative cooling rate, a much lower minimal temperature, a much greater warming rate, and a much greater thermal gradients compared with that of the simplified Endocare system. The numerical simulation indicates that the novel combined cryosurgery and hyperthermia system can provide an excellent curative effect in the corresponding cryotherapy. And the most attractive feature of this FEA framework is that it can be easily mastered by the surgeon without in-depth theory of heat transfer to analyze the cryosurgery process beforehand due to the friendly GUI (graphical user interface) of Ansys software.
authors.affiliation: Department of Thermal Science and Energy Engineering, University of Science and Technology of China, Hefei, China. ZhaoG@ustc.edu.cn
authors.forename: Gang
authors.initials: G
authors.lastname: Zhao
authors.forename: Xue-Fei
authors.initials: XF
authors.lastname: Bai
authors.forename: Da-Wei
authors.initials: DW
authors.lastname: Luo
authors.forename: Da-Yong
authors.initials: DY
authors.lastname: Gao
mesh_terms: D001831:Body Temperature; D003196:Computer Graphics; D003198:Computer Simulation; D003452:Cryosurgery / Q000379:methods*; D020342:Finite Element Analysis; D006358:Hot Temperature; D006979:Hyperthermia, Induced / Q000379:methods*; D008962:Models, Theoretical; D009369:Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy; D013814:Thermal Conductivity; D014584:User-Computer Interface