Preliminary data on monosymptomatic nocturnal enuresis in children and adolescents with type 1 diabetes.
OBJECTIVE
To evaluate the prevalence of monosymptomatic nocturnal enuresis (MNE) in a group of children and adolescents prior to the onset of type 1 diabetes (Dt1).


METHODS
We considered 88 patients with Dt1 with a mean age of 15.2 years over a period of 3 years. All patients were investigated by means of a questionnaire about the occurrence of MNE prior to the onset of Dt1. Each patient had normal urinalysis results, with no glycosuria, a normal urinary flow rate and no day-time symptoms such as urge incontinence or urgency.


RESULTS
We found that 24/88 patients (27.2%) were bedwetters before the onset of Dt1. After beginning insulin treatment, 7/24 bedwetters (29.2%) kept presenting MNE. In total, 7 of the initial 88 patients (7.9%) displayed persistent features of MNE.


CONCLUSIONS
The occurrence of MNE may overlap with symptoms of Dt1 but requires specific medical attention as a separate entity due to its possible persistence even when Dt1 has been controlled by insulin treatment.
Ferrara
Pietro
P
Department of Paediatric Sciences, Università Cattolica Sacro Cuore, "A. Gemelli" Hospital, Rome, Italy. pferrara@rm.unicatt.it
Rigante
Donato
D
D'Aleo
Carmen
C
Schiavino
Alessandra
A
Emmanuele
Valentina
V
Marrone
Giuseppina
G
Marietti
Giovanni
G
D000293:Adolescent; D017668:Age of Onset; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000453:epidemiology; D004775:Enuresis / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies