Common region CR1 for expression of antibiotic resistance genes.
The CR1 element defined by an orf513 gene encoding a putative recombinase and a recombination crossover site has been identified upstream of several antibiotic resistance genes in Enterobacteriaceae. This CR1 element was shown to bring promoter sequences that play a role in the expression of unrelated antibiotic resistance genes.
Rodriguez-Martinez
Jose-Manuel
JM
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris Sud, K-Bicêtre, France.
Poirel
Laurent
L
Canton
Rafael
R
Nordmann
Patrice
P
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004755:Enterobacteriaceae / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D045522:Recombinases / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D045522:Recombinases