Female adnexal tumor of probable wolffian origin: clinicopathological, immunohistochemical and cytofluorimetric analyses of a 22-year-old virgin. case report.
The term female adnexal tumor of probable Wolffian origin "FATWO" designs this tumor wich arises by the rare persisting remnants of the mesonephric duct (Wolffian duct). About 40 cases have been reported in literature. Few cases of recurrence have been reported, FATWO usually shows no signs of hormonal activity. We report a case of the youngest patient affected by FATWO in October 2002. At laparotomy the left adnexa were deformed by a well-capsulated mass, totally removed and sent to the pathologist with a specimen of peritoneal fluid and of the omentum. The histological examination showed a prevalent tubular structure with focal retiform area, without intraluminal mucines. Immunohistochemical findings of the case reported are similar to those described by other authors, except for inhibin which has not been detected by us. The cytofluorimetry showed the low presence of aneuploid cells, with a very low prolifing component (< 1%).
Balbi
G C
GC
Department of Obstetrics and Gynecology, Second University of Naples (SUN) U.O. Anatomic Pathology, A.O.R.N. Cardarelli, Italy.
Del Piano
L
L
Labriola
D
D
Visconti
S
S
Monteverde
A
A
Passaro
M
M
Monaco
R
R
Cardone
A
A
Rossiello
R
R
Panariello
S
S
Montone
L
L
D000291:Adnexal Diseases / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D001956:Broad Ligament; D005260:Female; D005434:Flow Cytometry; D005833:Genital Neoplasms, Female / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D014928:Wolffian Ducts