Empirical mode decomposition and synchrogram approach to cardiorespiratory synchronization.
We use the empirical mode decomposition method to decompose experimental respiratory signals into a set of intrinsic mode functions (IMFs), and consider one of these IMFs as a respiratory rhythm. We then use the Hilbert spectral analysis to calculate the instantaneous phase of the IMF. Heartbeat data are finally incorporated to construct the cardiorespiratory synchrogram, which is a visual tool for inspecting synchronization. We perform analysis on 20 data sets collected by the Harvard medical school from ten young (21-34 years old) and ten elderly (68-81 years old) rigorously screened healthy subjects. Our results support the existence of cardiorespiratory synchronization. We also investigate the origin of the cardiorespiratory synchronization by addressing the problem of correlations between regularities of respiratory and cardiac signals. Our analysis shows that regularity of respiratory signals plays a dominant role in the cardiorespiratory synchronization.
Wu
Ming-Chya
MC
Institute of Physics, Academia Sinica, Nankang, Taipei 11529, Taiwan. mcwu@phys.sinica.edu.tw
Hu
Chin-Kun
CK
D000328:Adult; D000368:Aged; D000465:Algorithms; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D005246:Feedback / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008954:Models, Biological; D010507:Periodicity; D015656:Respiratory Mechanics / Q000502:physiology*