Can we treat airway remodeling?
Asthma is a chronic disease that has been associated with structural changes of the airway wall. These changes lead to decreased reversibility of airway obstruction and have been understood as poorly reversible. Recent studies have proved that even some of the processes involved in airway remodeling may be reversible with early detection of the disease and appropriate anti inflammatory treatment. New treatments should be directed not only against inflammation itself but also against these chronic changes.
Pohunek
Petr
P
Prague, Czech Republic. petr.pohunek@Lfmotol.cuni.cz
D000280:Administration, Inhalation; D000818:Animals; D001249:Asthma / Q000188:drug therapy* / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D020545:Respiratory Mucosa / Q000187:drug effects / Q000473:pathology*; D016896:Treatment Outcome
D005938:Glucocorticoids