Concise review: scientific and ethical roadblocks to human embryonic stem cell therapy.
Despite the identified therapeutic potential of embryonic stem cells for treating human disease and injury, a number of roadblocks, scientific and ethical, stand in the way of progress toward this goal. We identify six areas of particular interest: tumorigenicity, animal product contamination, genetic compatibility, funding, cell type for transplantation, "embryo-friendly" derivation methods and discuss avenues for moving beyond the difficulties.
Gruen
Lori
L
Department of Philosophy, Wesleyan University, Middletown, Connecticut 06459-0170, USA.
Grabel
Laura
L
D046149:Embryo Culture Techniques / Q000379:methods; D033041:Embryo Research / Q000191:economics / Q000941:ethics; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D033581:Stem Cell Transplantation / Q000941:ethics / Q000379:methods* / Q000592:standards