Left ventricular diastolic dysfunction in obese women.
OBJECTIVE
To determine the direct effect of obesity on echocardiographic indices of diastolic left ventricular function


METHODS
44 obese (BMI > or =25 kg/m2) and 45 normal weight women were studied. They had no other pathological conditions. Echocardiographic indices of diastolic function were obtained, and dysfunction was assumed when at least two values differed by > or =2 SD from the normal weight group.


RESULTS
In obese subjects, the values of maximum velocity of active mitral filling (A) were increased and pulmonary diastolic velocity was decreased significantly (p< 0,01); all other diastolic variables were unchanged. Subclinical diastolic dysfunction tend to be more prevalent among obese subjects but it was not significantly different from non obese (p= 0.11), being present in nine obese (20.5%) and 4 normal (8.9%) subjects.


CONCLUSIONS
Subclinical left ventricular diastolic dysfunction is present in obese women.
Alwi
Idrus
I
Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta.
Harun
S
S
Sukmono
Satrio
S
Suwondo
Pradana
P
Oemardi
Maryantoro
M
Waspadji
Sarwono
S
Soegondo
Sidartawan
S
D000328:Adult; D016022:Case-Control Studies; D003971:Diastole / Q000502:physiology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D009765:Obesity / Q000503:physiopathology*; D018617:Ultrasonography, Doppler, Pulsed; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*