Postnatal respiratory distress in a dichorial twin with congenital thoracic neuroblastoma after assisted reproduction by intracytoplasmatic sperm injection.
We report on the case of a female twin with congenital thoracic neuroblastoma after conception via intracytoplasmatic sperm injection (ICSI). Birth occurred at 37 + 1-week gestation per primary sectio caesarea. Acute respiratory distress necessitated intubation and mechanical ventilation. Ultrasound and magnetic resonance imaging (MRI) showed a mass in the right upper thorax compressing the trachea. The tumor was subtotally excised and histological analysis revealed neuroblastoma. No further treatment was given. The residual primary tumor regressed spontaneously. Four years after diagnosis, both twins are healthy and normally developed.
Langer
Thorsten
T
University Clinic for Children and Adolescents, Erlangen, Germany. thorsten.langer@kinder.imed.uni-erlangen.de
Deeg
Karl-Heinz
KH
Hümmer
Peter
P
Paulides
Marios
M
Beck
Jörn-Dirk
JD
Klinge
Jens
J
D000328:Adult; D004200:Diseases in Twins; D005260:Female; D005784:Gene Amplification; D016259:Genes, myc; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D018365:Neoplasm, Residual; D009447:Neuroblastoma / Q000150:complications / Q000151:congenital* / Q000000981:diagnostic imaging / Q000235:genetics / Q000601:surgery; D011247:Pregnancy; D011877:Radionuclide Imaging; D012075:Remission, Spontaneous; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology*; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects; D013899:Thoracic Neoplasms / Q000150:complications / Q000151:congenital* / Q000000981:diagnostic imaging / Q000235:genetics / Q000601:surgery; D013908:Thoracotomy; D014429:Twins, Dizygotic; D014463:Ultrasonography