title: Colonization of the medial lumen is a risk factor for catheter-related bloodstream infection.
abstract: OBJECTIVE
  To analyze the colonization of each lumen and the risk factors for triple-lumen central venous catheter-related bloodstream infection (CRBI).
  
  
  METHODS
  Prospective, observational study in the medical-surgical intensive care unit (ICU) of a teaching hospital.
  
  
  METHODS
  A total of 120 patients requiring the insertion of a triple-lumen catheter.
  
  
  METHODS
  Cultures of the catheter.
  
  
  RESULTS
  The catheters were removed when CRBI was suspected or at discharge from ICU. At the removal time, blood cultures, a swab of the insertion site and a culture of the catheter tip were performed. Furthermore, we made quantitative cultures of the proximal, medial and distal lumen. We diagnosed CRBI in six patients (3.35 CRBI/1,000 days at risk), and we observed that in these patients colonization of the medial lumen was more frequent (5/6) than in patients without CRBI (9/114; p = 0.0001). The logistic regression analysis showed that colonization of the medial lumen was an independent risk factor for CRBI (OR 28.1, 95% CI 2.2-364.9).
  
  
  CONCLUSIONS
  Colonization of the medial lumen is an independent risk factor for triple-lumen catheter-related bloodstream infection, possibly due to the absence of use of this lumen.
authors.affiliation: Department of Intensive Care, Hospital Universitari de Girona Doctor Josep Trueta, Avda. de França s/n, 17007, Girona, Spain. uci.jmsirvent@htrueta.scs.es
authors.forename: Josep-Maria
authors.initials: JM
authors.lastname: Sirvent
authors.forename: Loreto
authors.initials: L
authors.lastname: Vidaur
authors.forename: María
authors.initials: M
authors.lastname: García
authors.forename: Patricia
authors.initials: P
authors.lastname: Ortiz
authors.forename: Jordi
authors.initials: J
authors.lastname: de Batlle
authors.forename: Montserrat
authors.initials: M
authors.lastname: Motjé
authors.forename: Alfons
authors.initials: A
authors.lastname: Bonet
mesh_terms: D016470:Bacteremia / Q000175:diagnosis* / Q000209:etiology*; D002405:Catheterization, Central Venous; D016009:Chi-Square Distribution; D003428:Cross Infection / Q000175:diagnosis* / Q000209:etiology*; D020878:Device Removal; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric