The influence of scopolamine and extreme temperatures on the lipid level in some mouse organs.
OBJECTIVE
The effect of scopolamine administration at dose 0,5 g/kg b.w. and high (+40 degrees C) and low (+4 degrees C) temperature on the level of triacyloglycerides, total lipids and cholesterol in the mouse liver, kidney and muscle of males and females.


METHODS
The homogenates of the liver, kidney and muscle were taken for examination. The concentrations of triacyloglycerides, total lipids and cholesterol was estimated according to the Bio-La-Tests (Poland).


RESULTS
The concentration of triacyloglycerides and total lipids in the liver, kidney and muscle increased of males and females after scopolamine injections and after exposure to high and low temperatures.


CONCLUSIONS
Scopolamine may effect an increase in the rate of the lipid metabolism.
Klusek
Jolanta
J
Department of Genetics, Institute of Biology, Swietokrzyska 15, 25-406 Kielce, Poland. j.klusek@pu.kielce.pl
Swiderska-Kołacz
Grazyna
G
Jóźwik
Artur
A
Kołataj
Adam
A
D000222:Adaptation, Physiological / Q000187:drug effects; D000704:Analysis of Variance; D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D003080:Cold Temperature; D005260:Female; D006358:Hot Temperature; D007668:Kidney / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D018727:Muscarinic Antagonists / Q000494:pharmacology*; D018482:Muscle, Skeletal / Q000378:metabolism*; D011897:Random Allocation; D012601:Scopolamine / Q000494:pharmacology*; D012737:Sex Factors; D014280:Triglycerides / Q000378:metabolism
D008055:Lipids; D018727:Muscarinic Antagonists; D014280:Triglycerides; D002784:Cholesterol; D012601:Scopolamine