title: [Female urogenital mycoplasma infection and drug sensitivity status in Changsha].
abstract: OBJECTIVE
  To survey mycoplasma infection in female urogenital tract and analyze the drug sensitivity of mycoplasma in Changsha.
  
  
  METHODS
  Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) were detected in 6566 cases of female urogenital tract infection by means of mycoplasma culture and drug sensitivity reagent kit. Sensitivity tests for 10 antibiotics were also performed.
  
  
  RESULTS
  A total of 2938 cases were mycoplasma-positive (positivity rate of 44.75%), including 2469 Uu-positive cases (37.6%), 52 Mh-positive cases (0.08%) and 417 cases positive for both Uu and Mh (6.35%). Josamycin, doxycycline, clarithromycin and azithromycin were more effective against Uu infection. Josamycin, doxycycline and thiamphenicol were more effective against Mh infection. Mixed infection with Uu and Mh was more resistant to most antibiotics but Josamycin and doxycycline.
  
  
  CONCLUSIONS
  The female urogenital mycoplasma infection results mainly from Uu. Compared with simple Uu or Mh infection, mixed infection with Uu and Mh has significantly greater resistance to a wider variety of drugs. Josamycin and doxycycline are the primary choice for female urogenital mycoplasma infection in Changsha.
authors.affiliation: Department of Dermatology, Third Xiangya Hospital of Central South University, Changsha 410013, China.
authors.forename: Cheng-xin
authors.initials: CX
authors.lastname: Zuo
authors.forename: Jin-hua
authors.initials: JH
authors.lastname: Huang
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.forename: Jian-yun
authors.initials: JY
authors.lastname: Lu
authors.forename: Ya-ping
authors.initials: YP
authors.lastname: Xiang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D004318:Doxycycline / Q000494:pharmacology / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D015570:Josamycin / Q000494:pharmacology / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D019535:Mycoplasma hominis / Q000187:drug effects*; D016869:Ureaplasma Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D016990:Ureaplasma urealyticum / Q000187:drug effects*; D002575:Uterine Cervicitis / Q000382:microbiology*
chemical_list: D015570:Josamycin; D004318:Doxycycline