title: Unprecedented selectivity in the formation of large-ring oligoimines from conformationally bistable chiral diamines.
abstract: [reaction: see text] Stereoselective formation of large macrocycles in "click-type" reactions is a current challenge. Chiral macrocycles of differing size and shape (e.g., rectanglimine or loopimine) were selectively obtained by cyclocondensation of terephthalaldehyde or isophthalaldehyde with conformationally bistable chiral diamines derived from trans-1,2-diaminocyclohexane and aromatic dianhydrides. This opens new opportunities for the programmed synthesis of large-ring molecular assemblies.
authors.affiliation: Department of Chemistry, A. Mickiewicz University, Poznan, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Kaik
authors.forename: Jacek
authors.initials: J
authors.lastname: Gawroński