Melnick- needles osteodysplasty presenting with quadriparesis.
Melnick-Needles syndrome or osteodysplasty, a monogenic heritable bone dysplasia, is characterized by a typical facies and characteristic radiological findings. Less than 70 well-documented cases have been reported in literature; most of them were sporadic. We report the first case from Eastern India in an adolescent male, who had cranio-vertebral junction anomalies and presented with spastic quadriparesis at the age of 13 years.
Bandyopadhyay
S K
SK
Department of Medicine, Nil Ratan Sircar Medical College and Hospital, 138, A J C Bose Road, Kolkata 700 014.
Ghosal
J
J
Chakrabarti
Nandini
N
Dutta
Anita
A
D000293:Adolescent; D002574:Cervical Vertebrae / Q000473:pathology*; D005799:Genes, Dominant; D008040:Genetic Linkage; D006801:Humans; D007194:India; D008297:Male; D010009:Osteochondrodysplasias / Q000235:genetics*; D010985:Platybasia / Q000473:pathology*; D011782:Quadriplegia / Q000235:genetics*