Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants.
The effect of hydrocortisone (HC), the steroid of lowest potency, and physiotherapy (PT) on non-retractile physiologic phimosis (PP) and the reduction of subsequent recurrent UTI was evaluated in male infants with UTI. Seventy-eight male infants with febrile UTI and nonretractile PP were prospectively randomized into HC (Plancol, n=39) and control (Vaseline, n=39) groups. Topical application of HC as a thin film around the preputial margin twice a day for four weeks with PT was instructed. The response rate in the HC group was 89.7% (35/39), which was significantly higher than the rate (20.5%; 8/39) in the control group (P<0.05). In the HC group, the response rate was much higher (96.1%) in the subgroup with PT than in the group without PT. Most of the response (88.5%) was observed within two weeks. During the following year, the recurrent rate of UTI was 7.1% (2/28) in the infants with retractile prepuces, which was significantly less than than the rate (29.6%; 8/27) in infants with nonretractile prepuces (P<0.05). In conclusion, topical HC and PT for 2-4 weeks proved to be a simple, safe and effective treatment for nonretractile PP in infants with UTI, and this procedure was beneficial in reducing recurrent UTI.
Lee
Jung Won
JW
Department of Pediatrics, Seoul Municipal Dongbu Hospital, Seoul, South Korea.
Cho
Su Jin
SJ
Park
Eun Ae
EA
Lee
Seung Joo
SJ
D000287:Administration, Topical; D003131:Combined Modality Therapy; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010688:Phimosis / Q000150:complications / Q000628:therapy*; D026741:Physical Therapy Modalities; D011446:Prospective Studies; D012008:Recurrence; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology
D006854:Hydrocortisone