title: Supply of human allograft tissue in Canada.
abstract: There is relatively little known about the supply for allograft tissues in Canada. The major aim of this study is to quantify the current or "Known Supply" of human allograft tissue (bone, tendons, soft tissue, cardiovascular, ocular and skin) from known tissue banks in Canada, to estimate the "Unknown Supply" of human allograft tissue available to Canadian users from other sources, and to investigate the nature and source of these tissue products. Two surveys were developed; one for tissue banks processing one or more tissue types and the other specific to eye banks. Thirty nine sites were initially identified as potential tissue bank respondent sites. Of the 39 sites, 29 sites indicated that they were interested in participating or would consider completing the survey. A survey package and a self-addressed courier envelope were couriered to each of 29 sites. A three week response time was indicated. The project consultants conducted telephone and email follow-up for incomplete data. Unknown supply was estimated by 5 methods. Twenty-eight of 29 sites (97%) completed and returned surveys. Over the past year, respondents reported a total of 5,691 donors (1,550 living and 4,141 cadaveric donors). Including cancellous ground bone, there were 10,729 tissue products produced by the respondent banks. Of these, 71% were produced by accredited banks and 32% were ocular tissues. Total predicted shortfall of allograft tissues was 31,860-66,481 grafts. Through estimating Current supply, and compiling additional qualitative information, this study has provided a snapshot of the current Canadian supply and shortfall of allograft tissue grafts.
authors.affiliation: Clinical Islet Transplant Program, Department of Surgery, University of Alberta, 8215 112 street, Suite 210, College Plaza, T6G 2C8 Edmonton, Alberta, Canada. jonathan.lakey@ualberta.ca
authors.forename: Jonathan R T
authors.initials: JR
authors.lastname: Lakey
authors.forename: Mohammadreza
authors.initials: M
authors.lastname: Mirbolooki
authors.forename: Christina
authors.initials: C
authors.lastname: Rogers
authors.forename: Jim
authors.initials: J
authors.lastname: Mohr
mesh_terms: D002113:Calcification, Physiologic; D002170:Canada; D006801:Humans; D014015:Tissue Banks / Q000600:supply & distribution*; D020858:Tissue and Organ Harvesting; D009927:Tissue and Organ Procurement / Q000706:statistics & numerical data*; D014184:Transplantation, Homologous