title: HCNet: a database of heart and calcium functional network.
abstract: CONCLUSIONS
  The Heart and Calcium functional Network (HCNet) database is a collection of functional gene modules calculated from the microarray data compendium available from the GEO database. It is a specialized database designed to assist experimentalists for cardiac calcium signaling research by providing the pre-calculated gene clusters and their potential correlation network in heart. In the current release of HCNet, 57 functional modules from 786 target genes obtained by a bi-clustering analysis of 381 microarray datasets are available. Detailed information of the clusters such as expression profiles, network diagrams is provided in two categories, heart-specific genes and heart-specific genes along with calcium toolkit genes. Overrepresented gene ontological categories and transcription factors in each cluster are also provided to infer the biological implications of the detected functional modules.
  
  
  BACKGROUND
  HCNet is available at http://sbrg2.gist.ac.kr/hcnet.
authors.affiliation: Department of Life Science, Gwangju Institute of Science and Technology 1 Oryong-dong, Buk-gu, Gwangju 500-712, Korea.
authors.forename: Seong-Eui
authors.initials: SE
authors.lastname: Hong
authors.forename: Seong-Hwan
authors.initials: SH
authors.lastname: Rho
authors.forename: Young Il
authors.initials: YI
authors.lastname: Yeom
authors.forename: Do Han
authors.initials: DH
authors.lastname: Kim
mesh_terms: D000465:Algorithms; D002118:Calcium / Q000378:metabolism*; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D020869:Gene Expression Profiling; D006321:Heart / Q000502:physiology; D008957:Models, Genetic; D009206:Myocardium / Q000378:metabolism*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D010363:Pattern Recognition, Automated; D011381:Programming Languages; D015398:Signal Transduction
chemical_list: D002118:Calcium