title: [Fever and exanthema as manifestations of the second stage of syphilis].
abstract: A man aged 30 had been suffering from episodes of fever for several weeks. He had diarrhoea and had developed generalized maculopapular exanthema that also affected the palms of his hands and soles of his feet. After viral causes were excluded the symptoms proved to be caused by syphilis. His condition was complicated by uveitis. The patient recovered after a single dose of benzyl penicillin and local mydratics and corticosteroid eye drops. The incidence of syphilis is rising and its clinical spectrum is broad. Therefore in patients with fever and exanthema of unknown origin this disease should be considered. One should be aware of the wide variety of complications that can result from syphilis.
authors.affiliation: Jeroen Bosch Ziekenhuis, locatie Carolus, Hertogenbosch.
authors.forename: M W
authors.initials: MW
authors.lastname: Heijstek
authors.forename: W R O
authors.initials: WR
authors.lastname: Goslings
authors.forename: S
authors.initials: S
authors.lastname: Shamelian
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D008297:Male; D010400:Penicillin G / Q000627:therapeutic use; D013587:Syphilis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome; D014605:Uveitis / Q000209:etiology / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G