HIV may deplete most CD4 lymphocytes by a mechanism involving signaling through its receptors on non-permissive resting lymphocytes.
Cloyd
Miles W
MW
Department of Pathology, University of Texas Medical Branch, Galveston 77555, USA.
Ji
Jiaxiang
J
Smith
Melissa
M
Braciale
Vivian
V
D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism* / Q000473:pathology*; D006678:HIV / Q000472:pathogenicity*; D006801:Humans; D007422:Intestines / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism*; D015398:Signal Transduction
D011948:Receptors, Antigen, T-Cell