title: A path model of the effects of spirituality on depressive symptoms and 24-h urinary-free cortisol in HIV-positive persons.
abstract: OBJECTIVE
  The present investigation examined the associations among spirituality, positive reappraisal coping, and benefit finding as they relate to depressive symptoms and 24-h urinary-free-cortisol output.
  
  
  METHODS
  Following an initial screening appointment, 264 human-immunodeficiency-virus-positive men and women on highly active antiretroviral therapy provided 24-h urine samples and completed a battery of psychosocial measures.
  
  
  RESULTS
  Spirituality was associated with higher positive reappraisal coping and greater benefit finding. Benefit finding and positive reappraisal coping scores were, in turn, both related to lower depressive symptoms. Finally, we determined that benefit finding was uniquely predictive of decreased 24-h urinary-free cortisol output.
  
  
  CONCLUSIONS
  Positive reappraisal coping and benefit finding may co-mediate the effect of spirituality on depressive symptoms, and benefit finding may uniquely explain the effect of spirituality on 24-h cortisol output.
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, FL 33146, USA.
authors.forename: Adam W
authors.initials: AW
authors.lastname: Carrico
authors.forename: Gail
authors.initials: G
authors.lastname: Ironson
authors.forename: Michael H
authors.initials: MH
authors.lastname: Antoni
authors.forename: Suzanne C
authors.initials: SC
authors.lastname: Lechner
authors.forename: Ron E
authors.initials: RE
authors.lastname: Durán
authors.forename: Mahendra
authors.initials: M
authors.lastname: Kumar
authors.forename: Neil
authors.initials: N
authors.lastname: Schneiderman
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001143:Arousal / Q000502:physiology; D003863:Depression / Q000523:psychology* / Q000652:urine; D005260:Female; D006679:HIV Seropositivity / Q000188:drug therapy / Q000523:psychology* / Q000652:urine; D018451:Homosexuality, Male / Q000523:psychology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D010555:Personality Inventory; D011594:Psychometrics; D016032:Randomized Controlled Trials as Topic; D012069:Religion and Psychology; D029181:Spirituality
chemical_list: D006854:Hydrocortisone