Information capacity of nucleotide sequences and its applications.
The information capacity of nucleotide sequences is defined through the specific entropy of frequency dictionary of a sequence determined with respect to another one containing the most probable continuations of shorter strings. This measure distinguishes a sequence both from a random one, and from ordered entity. A comparison of sequences based on their information capacity is studied. An order within the genetic entities is found at the length scale ranged from 3 to 8. Some other applications of the developed methodology to genetics, bioinformatics, and molecular biology are discussed.
Sadovsky
M G
MG
Institute of Biophysics of Siberian Division of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russia. msad@icm.krasn.ru
D019295:Computational Biology; D018742:DNA, Chloroplast / Q000235:genetics; D004271:DNA, Fungal / Q000235:genetics; D016681:Genome, Fungal; D018745:Genome, Plant; D023281:Genomics / Q000706:statistics & numerical data; D012568:Schizosaccharomyces / Q000235:genetics; D017422:Sequence Analysis, DNA / Q000706:statistics & numerical data*
D018742:DNA, Chloroplast; D004271:DNA, Fungal