title: Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.
authors.forename: Vikramjit S
authors.initials: VS
authors.lastname: Kanwar
authors.forename: Jennifer
authors.initials: J
authors.lastname: Pearce
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D002955:Leucovorin; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy; D023303:Oxazolidinones / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*; D017366:Serotonin Receptor Agonists / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D014363:Tryptamines / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use
chemical_list: D023303:Oxazolidinones; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C089750:zolmitriptan; D002955:Leucovorin; D008727:Methotrexate