Beta-blocker use in elderly ED patients with acute myocardial infarction.
BACKGROUND
Despite the effectiveness of early beta-blocker (BB) use in reducing mortality in acute myocardial infarction (AMI), they remain underutilized in the emergency department (ED) management of AMI. The elderly, with higher AMI mortality, and women, may be particularly vulnerable to underutilization of BB.


OBJECTIVE
To determine the effect of age and gender on BB use in AMI in the ED.


METHODS
A retrospective study of all ST-elevation AMI (STEMI) ED patients presenting to a community hospital ED from 2001 to 2003. Any contraindication to BB use (hypotension, bradycardia, AV block, active bronchospasm, and active congestive heart failure) was determined. Chi-square analysis was used to determine differences by gender and age.


RESULTS
Three hundred eighty-five patients with STEMI were identified. Thirty-eight percent were women and 71% were over 60 years of age. Of the 270 (70%) who did not receive BB, 141 (52%) had contraindications to BB use. The total BB eligible group was 244 (63%). Of patients without contraindications to BB, 53% did not receive BB in the ED. By gender, 83 (54%) males and 46 (51%) females did not receive BB (P=.669). By age, 96 subjects (59%) over age 60 and 33 subjects (41%) under age 60 did not receive BB (P=.011).


CONCLUSIONS
Despite convincing evidence of effectiveness, BB remain underutilized in ED management of AMI, especially in the elderly. There does not appear to be a gender difference in BB use. Education programs should be directed towards emergency physicians regarding BB use in AMI, especially in elderly ED patients.
Vega
David D
DD
Department of Emergency Medicine, York Hospital, York, PA 17405, USA. dvega@wellspan.org
Dolan
Kendra L
KL
Pollack
Marc L
ML
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D000075202:Contraindications; D004363:Drug Utilization; D004636:Emergency Service, Hospital; D005260:Female; D006764:Hospitals, Community; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D012189:Retrospective Studies; D012737:Sex Factors
D000319:Adrenergic beta-Antagonists