Lung mass caused by Phoma exigua.
We describe a well documented case of a fatal Phoma exigua lung infection in a patient with acute myeloid leukaemia and diabetes. The infection was histology and culture proven and a PCR assay was developed for detecting P. exigua DNA in deparaffinized lung-biopsy material. Confirmation of rare fungal pathogen infections requires a multidisciplinary approach involving clinical observations, mycology, histopathology and radiology.
Balis
Evangelos
E
Third Department of Internal Medicine, Medical School, University of Athens, Sotiria General and Chest Hospital, Athens, Greece. evanbalis@yahoo.co.uk
Velegraki
Aristea
A
Fragou
Archodula
A
Pefanis
Angelos
A
Kalabokas
Theodore
T
Mountokalakis
Theodore
T
D000208:Acute Disease; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000235:genetics / Q000302:isolation & purification*; D017809:Fatal Outcome; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D008297:Male; D011013:Pneumonectomy; D016133:Polymerase Chain Reaction / Q000379:methods; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents