title: Long-term habituation in the marine mollusc Tritonia diomedea.
abstract: Tritonia diomedea is one of several gastropod molluscs used to study cellular mechanisms of learning and memory. Previous studies in this organism have focused on short-term habituation and sensitization. This report presents the first detailed description of long-term habituation in Tritonia. Experimental animals were given 11 swim sessions, each consisting of 10 trials, over 6 days, during which they typically displayed an initial sensitization, followed by short-term, within-session habituation. Responses were compared to controls, which were given a single stimulus per day. Cycle number habituation steadily accumulated over the days of training, and then persisted for at least 2 days after the end of training. These findings will permit comparative studies of the cellular mechanisms of short- and long-term memory in this highly tractable model system.
authors.affiliation: Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, Illinois 60064, USA. william.frost@rosalindfranklin.edu
authors.forename: William N
authors.initials: WN
authors.lastname: Frost
authors.forename: Cindy L
authors.initials: CL
authors.lastname: Brandon
authors.forename: Carin
authors.initials: C
authors.lastname: Van Zyl
mesh_terms: D000818:Animals; D004924:Escape Reaction; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D008568:Memory / Q000502:physiology*; D013550:Swimming; D049871:Tritonia Sea Slug / Q000502:physiology*