title: Two new benzylbenzoate glucosides from Curculigo orchioides.
abstract: An extract from in vitro cultures of Curculigo orchioides grown as bulbils in shake flasks, afforded two new glucosides of substituted benzylbenzoate - curculigoside C (3) and curculigoside D (4) - together with two known compounds - curculigoside A (1) and curculigoside B (2). Their structures were elucidated on the basis of spectral evidence, in particular by using 2D NMR methods. Their vasoactive properties were assessed in isolated rat aortic rings.
authors.affiliation: Groupe d'Etude des Substances Naturelles à Activités Biologiques, EA 3675, Université de Bordeaux 2, Bordeaux, France.
authors.forename: Josep
authors.initials: J
authors.lastname: Valls
authors.forename: Tristan
authors.initials: T
authors.lastname: Richard
authors.forename: Fabienne
authors.initials: F
authors.lastname: Larronde
authors.forename: Véronique
authors.initials: V
authors.lastname: Leblais
authors.forename: Bernard
authors.initials: B
authors.lastname: Muller
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Delaunay
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Monti
authors.forename: K G
authors.initials: KG
authors.lastname: Ramawat
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Mérillon
mesh_terms: D000818:Animals; D001011:Aorta / Q000187:drug effects; D001593:Benzyl Compounds / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D031408:Curculigo; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects; D005960:Glucosides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D014661:Vasoconstriction / Q000187:drug effects*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D001593:Benzyl Compounds; D005960:Glucosides; D010936:Plant Extracts; D014662:Vasoconstrictor Agents