Anti-inflammatory cytokines in subclinical carotid atherosclerosis.
Some studies have shown correlations between selected proinflammatory factors and carotid atherosclerosis. It has not been established whether anti-inflammatory cytokines are associated with carotid intima-media thickness (IMT), an ultrasound surrogate marker of atherosclerosis. Therefore, the authors studied the relationship between the carotid IMT and serum levels of interleukin (IL)-10 and transforming growth factor-beta1 in 76 subjects. They discovered that lower IL-10 levels were associated with increased mean IMT in common carotid arteries.
Ambrosius
Wojciech
W
Department of Neurology, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland. wambrosius@amp.edu.pl
Kazmierski
Radoslaw
R
Michalak
Slawomir
S
Kozubski
Wojciech
W
D050197:Atherosclerosis / Q000097:blood* / Q000000981:diagnostic imaging*; D015415:Biomarkers / Q000097:blood; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D002340:Carotid Artery Diseases / Q000097:blood* / Q000000981:diagnostic imaging* / Q000453:epidemiology; D016207:Cytokines / Q000097:blood; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood; D016753:Interleukin-10 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011044:Poland; D016212:Transforming Growth Factor beta / Q000097:blood*; D014463:Ultrasonography
D015415:Biomarkers; D016207:Cytokines; D018836:Inflammation Mediators; D016212:Transforming Growth Factor beta; D016753:Interleukin-10