Eating restraint is negatively associated with biomarkers of bone turnover but not measurements of bone mineral density in young women.
Relationships among bone mineral density (BMD), bone turnover markers, cortisol, calcium and vitamin D intakes, and cognitive eating restraint score were examined. Sixty-five healthy women, ages 18 to 25 years, had total body, spine, hip, and forearm BMD measured by dual-energy x-ray absorptiometry. Serum osteocalcin, urinary cross-linked N-telopeptide of type I collagen (NTx), and salivary cortisol were measured, and intakes of calcium and vitamin D were estimated from questionnaires. Cognitive eating restraint scores were determined from the Eating Inventory. Associations between measures were analyzed by Pearson correlations; predictors of BMD and bone turnover markers were tested using stepwise regression. Serum osteocalcin (P<0.01) and urinary NTx (P<0.05) were negatively related to cognitive eating restraint score. Intakes of calcium (P<0.05) and vitamin D (P<0.05) were associated with forearm BMD. Regression analyses indicated that vitamin D intake predicted total body (P<0.08) and forearm (P<0.01) BMD. Negative associations between cognitive eating restraint score and bone biomarkers suggest a reduction in bone remodeling, not reflected in current BMD.
Nickols-Richardson
Sharon M
SM
Department of Human Nutrition, Foods, and Exercise, 225 Wallace Hall, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0430, USA. snrichar@vt.edu
Beiseigel
Jeannemarie M
JM
Gwazdauskas
Frank C
FC
D015502:Absorptiometry, Photon / Q000379:methods; D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000032:analysis; D015519:Bone Density / Q000502:physiology*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D016723:Bone Remodeling / Q000502:physiology*; D001842:Bone and Bones / Q000378:metabolism*; D002136:Calcium, Dietary / Q000008:administration & dosage; D024042:Collagen Type I / Q000652:urine; D004435:Eating; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D015675:Osteocalcin / Q000097:blood; D010455:Peptides / Q000652:urine; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012463:Saliva / Q000737:chemistry; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D014807:Vitamin D / Q000008:administration & dosage
D015415:Biomarkers; D050071:Bone Density Conservation Agents; D002136:Calcium, Dietary; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D015675:Osteocalcin; D014807:Vitamin D; D006854:Hydrocortisone