title: Enhanced production of scleroglucan by Sclerotium rolfsii MTCC 2156 by use of metabolic precursors.
abstract: The aim of this work was to study the effect of addition of different amino acids and sugar nucleotides as metabolic precursors on the production of scleroglucan. A maximum yield of 20.00 g/l and 22.32 g/l was obtained with optimized media supplemented with L-lysine (1.1 mM) and uridine mono-phosphate (UMP), respectively as compared to 16.52 g/l scleroglucan achieved with the control in the absence of metabolic precursors.
authors.affiliation: Food Engineering and Technology Department, Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai 400 019, India.
authors.forename: Shrikant A
authors.initials: SA
authors.lastname: Survase
authors.forename: Parag S
authors.initials: PS
authors.lastname: Saudagar
authors.forename: Rekha S
authors.initials: RS
authors.lastname: Singhal
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D005658:Fungi / Q000378:metabolism*; D005936:Glucans / Q000096:biosynthesis*; D013997:Time Factors; D014532:Uridine Diphosphate Glucose / Q000378:metabolism; D014542:Uridine Monophosphate / Q000378:metabolism
chemical_list: D000596:Amino Acids; D005936:Glucans; C045938:scleroglucan; D014542:Uridine Monophosphate; D014532:Uridine Diphosphate Glucose