title: [Bezafibrate alone is an effective first-line therapy for primary sclerosing cholangitis: a case report].
abstract: The patient was a 58-year-old female. Though she had been in good health, increased hepatobiliary enzymes were detected in a health examination. She visited our hospital for close examination. The serum IgG4 level was normal, but ERCP and MRCP showed band-like stricture and beaded appearance of the bile ducts. A diagnosis of primary sclerosing cholangitis (PSC) was made. Since hyperlipidemia was also observed, oral administration of bezafibrate (400mg/day) alone was performed as the initial treatment, and transaminase, ALP, and GGT rapidly decreased. These results suggested that the initial administration of bezafibrate alone is effective against PSC.
authors.affiliation: Gondoh Medical Clinic.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Gondoh
authors.forename: Tetsujiro
authors.initials: T
authors.lastname: Ono
authors.forename: Kenji
authors.initials: K
authors.lastname: Miyakoda
authors.forename: Michita
authors.initials: M
authors.lastname: Mukasa
authors.forename: Atsushi
authors.initials: A
authors.lastname: So
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Imamura
authors.forename: Michio
authors.initials: M
authors.lastname: Sata
mesh_terms: D000284:Administration, Oral; D001629:Bezafibrate / Q000008:administration & dosage*; D015209:Cholangitis, Sclerosing / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D008875:Middle Aged
chemical_list: D000960:Hypolipidemic Agents; D001629:Bezafibrate