Musidunin and musiduol, insect antifeedants from Croton jatrophoides.
Two novel limonoids, musidunin (1) and musiduol (2), were isolated from a methanol extract of Croton jatrophoides by bioassay-guided fractionation. Their structures were established by extensive NMR experiments. Interestingly, A,B-seco limonoid 1 contains a unique acetal annulation of A, A', and B' rings. Both limonoids exhibited antifeedant activities against two pests, Pectinophora gossypiella and Spodoptera frugiperda.
Nihei
Ken-ichi
K
Department of Applied Biochemistry, Faculty of Agriculture, Utsunomiya University, Utsunomiya, Tochigi 321-0943, Japan.
Asaka
Yukihiro
Y
Mine
Yoshihiro
Y
Yamada
Yoichi
Y
Iigo
Masayuki
M
Yanagisawa
Tadashi
T
Kubo
Isao
I
D000818:Animals; D029802:Croton / Q000737:chemistry*; D005247:Feeding Behavior / Q000187:drug effects*; D007630:Kenya; D007814:Larva / Q000187:drug effects; D007915:Lepidoptera / Q000187:drug effects*; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010572:Pest Control, Biological; D010946:Plants, Medicinal / Q000737:chemistry*
D036701:Limonins; C512097:musidunin; C512098:musiduol