Multiple oral fibropapillomatosis as an initial manifestation of Cowden Syndrome. Case report.
Cowden syndrome is a rare hereditary disease included within hamartoma-type gastrointestinal polyposis. It is characterised by associated mucocutaneous anomalies and by the extraordinary tendency to develop malignant neoplasia, mainly in the breast and thyroid. Early diagnosis of the syndrome and adequate tumoral screening in patients with mucocutaneous papillomatosis make it possible to make an earlier diagnosis of associated pathologies which have great morbidity when detected late. We present the case of a patient diagnosed with Cowden syndrome after consultation for labial papillomatous lesions of long evolution who was subsequently treated for breast and kidney cancer in initial stages. The correct diagnosis of a banal pathology of oral mucosa made it possible for us to take early action against the neoplastic pathology associated with this disease.
Capitán Cañadas
Luis Miguel
LM
Maxillofacial and Oral Surgery Service, Virgen de las Nieves University Hospital, Granada. luismxf@hotmail.com
Salinas Sánchez
José Luis
JL
Martínez Castillo
Sergio Luis
SL
Labrot Moleón
Ildefonso Leopoldo
IL
Durán Moreno
David
D
Sánchez López
Darío
D
Valencia Laseca
Eduardo
E
D000328:Adult; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis*; D006801:Humans; D009062:Mouth Neoplasms / Q000175:diagnosis*; D010212:Papilloma / Q000175:diagnosis*