title: Management of abnormal uterine hemorrhage with atypical endometrial hyperplasia by transcervical resection of endometrium.
abstract: The aim of the study was to assess the feasibility and effect of treating atypical endometrial hyperplasia (AEH) with transcervical resection of endometrium (TCRE). Five cases of AEH incapable of hysterectomy for various reasons were treated with TCRE. All patients were followed up for 3-4 years postoperation to evaluate the thickness of endometrium, uterine cavity, and prognosis of the disease. All the patients provided informed consent for TCRE. In all five cases treated with TCRE, case 1 was for senility, hypertension, diabetes mellitus, and obesity; case 4 for senility, obsolete cerebral infarction, and hemiplegia; case 5 for uremia and chronic dysfunction of coagulation after renal transplantation; cases 2 and 3 for rejection of hysterectomy. All cases were followed up for more than 3 years after operation. Four had amenorrhea and one had dropping menses. The thickness of endometrium was no more than 5 mm in all the cases. TCRE is one available microinvasive surgery alternative to hysterectomy for AEH patients contraindicated to hysterectomy.
authors.affiliation: Obstetrics and Gynecology Hospital, Diagnostic & Treatment Center for Cervical Disease, Fudan University, 419 Fang-xie Road, Shanghai 200011, China. suilong@sh163.net
authors.forename: L
authors.initials: L
authors.lastname: Sui
authors.forename: F
authors.initials: F
authors.lastname: Xie
authors.forename: B
authors.initials: B
authors.lastname: Cao
mesh_terms: D000368:Aged; D000075202:Contraindications; D004714:Endometrial Hyperplasia / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D004717:Endometrium / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007044:Hysterectomy; D015907:Hysteroscopy / Q000379:methods*; D008875:Middle Aged; D014592:Uterine Hemorrhage / Q000150:complications / Q000601:surgery*