title: [Systemic sclerosis and cancer].
abstract: The combination of skin induration with clinical features such as dyspnea, facial telangiectasia, digital infarctions and/or dysphagia supports the diagnosis of systemic sclerosis. The oesophageal dysmotility is associated with symptoms which may delay the diagnosis of gastro-oesophageal cancer. Herein we report a case of long standing systemic sclerosis with heartburn and dysphagia symptoms which were monitored closely. Unfortunately, these symptoms delayed the diagnosis of gastric adenocarcinoma. This case prompted us to review the evidence of the association of cancer and systemic sclerosis and if any oncologic evaluation is required during the follow-up of patients affected with systemic sclerosis.
authors.affiliation: Service de Médecine Interne, Département de Médecine, CHUV, Lausanne. levratemmanuel@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Levrat
authors.forename: G
authors.initials: G
authors.lastname: Waeber
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D004940:Esophageal Stenosis / Q000175:diagnosis / Q000473:pathology; D004943:Esophagogastric Junction / Q000473:pathology; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology; D005148:Facial Dermatoses / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000473:pathology; D012594:Scleroderma, Localized / Q000175:diagnosis / Q000473:pathology; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000473:pathology; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology