title: Drying of DNA droplets.
abstract: The evaporation kinetics of droplets containing DNA was studied, as a function of DNA concentration. Drops containing very low DNA concentrations dried by maintaining a constant base, whereas those with high concentration dried with a constant contact angle. To understand this phenomenon, the distribution of the DNA inside the droplet was measured using confocal microscopy. The results indicated that the DNA was condensed mostly on the surface of the droplets. In the case of high concentration droplets, it formed a shell, whereas isolated islands were found for droplets of low DNA concentrations. Rheologic results indicate the formation of a hydro gel in the low concentration drops, whereas phase separation between the self-assembled DNA structures and the water phase occurred at higher concentration.
authors.affiliation: Department of Materials Science and Engineering, State University of New York at Stony Brook, New York 11794, USA. mrafailovich@notec.cc.sunysb.edu
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Fang
authors.forename: Bingquan
authors.initials: B
authors.lastname: Li
authors.forename: Eric
authors.initials: E
authors.lastname: Petersen
authors.forename: Young-Soo
authors.initials: YS
authors.lastname: Seo
authors.forename: Vladimir A
authors.initials: VA
authors.lastname: Samuilov
authors.forename: Yong
authors.initials: Y
authors.lastname: Chen
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Sokolov
authors.forename: Chwen-Yang
authors.initials: CY
authors.lastname: Shew
authors.forename: Miriam H
authors.initials: MH
authors.lastname: Rafailovich
mesh_terms: D010582:Bacteriophage lambda / Q000737:chemistry*; D004279:DNA, Viral / Q000737:chemistry*; D003890:Desiccation; D018613:Microscopy, Confocal; D013499:Surface Properties
chemical_list: D004279:DNA, Viral