Genomewide evolutionary rates in laboratory and wild yeast.
As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated mutations in the lab. We report a low-to-intermediate rate of protein evolution in this strain relative to wild isolates.
Ronald
James
J
Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Tang
Hua
H
Brem
Rachel B
RB
D019143:Evolution, Molecular; D016681:Genome, Fungal; D009154:Mutation; D010802:Phylogeny; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D015003:Yeasts / Q000235:genetics*
D029701:Saccharomyces cerevisiae Proteins