title: Multifocal posterior uveitis in Crohn's disease.
abstract: OBJECTIVE
  To report a case of rare posterior eye manifestation of Crohn's disease preceding recurrence of inflammatory bowel disease.
  
  
  METHODS
  Case report with ophthalmoscopic findings, fluorescein/indocyanin green angiograms, automated perimetry and multifocal-ERG.
  
  
  RESULTS
  The perimetry revealed absolute and relative scotomas corresponding to multifocal inflammatory lesions in the retina and choroid, reduced a/b amplitudes in multifocal-ERG and hypofluorescent dots in angiography. Under oral prednisolone visual defects, ophthalmoscopic and angiographic findings resolved, while a/b amplitudes remained mildly reduced. The ocular changes occurred without systemic hypertension and were followed by a new episode of intestinal symptoms.
  
  
  CONCLUSIONS
  Multifocal inflammatory lesions in the retina and choroid in patients with Crohn's disease may occur and may precede a recurrent intestinal episode. Crohn's patients should be carefully followed up in collaboration with internal medicine specialists.
authors.affiliation: Department of Ophthalmology, At St. Franziskus Hospital, Hohenzollernring 74, 48145, Muenster, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Tappeiner
authors.forename: J
authors.initials: J
authors.lastname: Dohrmann
authors.forename: G
authors.initials: G
authors.lastname: Spital
authors.forename: A
authors.initials: A
authors.lastname: Heiligenhaus
mesh_terms: D000328:Adult; D004396:Coloring Agents; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007208:Indocyanine Green; D011239:Prednisolone / Q000627:therapeutic use; D012607:Scotoma / Q000209:etiology; D015866:Uveitis, Posterior / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D004396:Coloring Agents; D005938:Glucocorticoids; D011239:Prednisolone; D007208:Indocyanine Green