title: Breast CT: potential for breast cancer screening and diagnosis.
abstract: Although screening mammography has been shown to be effective in reducing breast cancer mortality, a new technique called breast computed tomography (CT) is being studied in the hope that breast cancer can be detected even earlier. A prototype unit has been designed, fabricated and tested at the University of California, Davis, USA, and is currently being used in a Phase II clinical trial to study the feasibility of breast CT for breast cancer detection and diagnosis. A total of 46 volunteers and patients have been imaged, and the breast CT images show impressive anatomical detail of the breast that is not appreciated in mammography. The radiation dose levels needed to produce excellent image quality are equal to two-view mammography. Further study of breast CT is needed to better understand its potential role in breast cancer screening and diagnosis.
authors.affiliation: University of California, Davis, Radiology Research, UC Davis Medical Center, Sacramento, CA 95817, USA. jmboone@ucdavis.edu
authors.forename: John M
authors.initials: JM
authors.lastname: Boone
authors.forename: Karen K
authors.initials: KK
authors.lastname: Lindfors
mesh_terms: D001940:Breast / Q000528:radiation effects; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography; D014057:Tomography, X-Ray Computed