title: Cystic renal cell carcinoma--rare clinical finding. Radiographic variations of tumor/cyst appearance and further diagnostic work-up.
abstract: OBJECTIVE
  To review the cases of cystic renal cell carcinoma and multilocular cystic nephroma, point out the radiographic variations and define further diagnostic work-up.
  
  
  METHODS
  Between 2003 and 2005 5 patients with suspected cystic renal cell carcinoma were treated surgically (1 pt underwent radical nephrectomy, 1 pt laparoscopic cyst decortication, 3 pts ablation), 2 patients with multilocular cystic nephroma underwent ultrasound guided biopsy.
  
  
  RESULTS
  Histopathologic examination confirmed cystic renal cell carcinoma (CRCC) T1aNOM0 Fuhrman grade 1 in 3 cases, T1bN0M0 Fuhrman grade 2 in one case. One patient with suspected tumor inside the cyst wall who underwent laparoscopic cyst decortication was excluded (final histology confirmed organized hematoma in the cyst wall). Biopsy in 2 patients with multilocular cystic nephroma did not confirm the presence of malignant cells. The mean tumor size was 4.2 cm (range 3.7 to 5.5) for CRCC and 4.7 cm (range 4 to 4.5 cm) for multilocular cystic nephroma. All 4 cases of CRCC were clear cell type.
  
  
  CONCLUSIONS
  In conclusion according to the data described and from our study, tumor/cyst co-existence requires further surgical exploration in group 2, 3, 4. Small cystic renal cell carcinomas up to 4 cm in diameter have usually favourable pathology and prognosis, which offers the minimally invasive nephron-sparing treatment options such as excision, ablation or partial nephrectomy (Fig. 9, Ref. 18).
authors.affiliation: Department of Urology, University Hospital, Faculty of Medicine, Comenius University, Bratislava, Slovakia. pweibl@yahoo.com
authors.forename: P
authors.initials: P
authors.lastname: Weibl
authors.forename: I
authors.initials: I
authors.lastname: Lutter
authors.forename: J
authors.initials: J
authors.lastname: Breza
authors.forename: J
authors.initials: J
authors.lastname: Pechan
authors.forename: M
authors.initials: M
authors.lastname: Blazko
authors.forename: T
authors.initials: T
authors.lastname: Gajdosova
authors.forename: D
authors.initials: D
authors.lastname: Pindak
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D003560:Cysts / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011859:Radiography