Increased cognitive load during simple and complex motor tasks in acute stage after stroke.
The aim of this study was to assess the activation of primary motor cortex, prefrontal cortex and parietal cortex during simple and complex motor tasks performed with the hemiparetic and non-hemiparetic hand.


METHODS
Seven patients after stroke in the left brain hemisphere were included in the study. Functional magnetic resonance imaging (fMRI) was performed in the first and third week, and in three patients also three months after the stroke.


RESULTS
Performance of both the simple and the complex tasks with the hemiparetic or non-hemiparetic hand resulted in activations of the motor cortex, prefrontal cortex and parietal cortex in majority of the consecutive fMRI sessions. Three months after the stroke fMRI data revealed reduced activation of primary motor cortex and parietal cortex in the contralesional hemisphere during the performance of the simple task by the hemiparetic hand. During the complex task, the reduction of activation was less prominent.


CONCLUSIONS
Results of the present study suggest that in mildly impaired stroke patients a bilateral activation of prefrontal and parietal cortex may participate in the recovery process from stroke. The potential for measurement of cortical rehabilitation is discussed.
Puh
Urska
U
University of Ljubljana, University College for Health Studies, Ljubljana, Slovenia. urska.puh@vsz.uni-lj.si
Vovk
Andrej
A
Sevsek
France
F
Suput
Dusan
D
D000368:Aged; D002540:Cerebral Cortex / Q000503:physiopathology*; D003071:Cognition; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D009068:Movement; D010291:Paresis / Q000209:etiology / Q000503:physiopathology*; D011597:Psychomotor Performance; D020127:Recovery of Function; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000503:physiopathology*