title: Proteome analysis of resting human neutrophils.
abstract: Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis-mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural.
authors.affiliation: Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil.
authors.forename: Mariana
authors.initials: M
authors.lastname: de Souza Castro
authors.forename: Natan Monsores
authors.initials: NM
authors.lastname: de Sá
authors.forename: Renata Pedroza
authors.initials: RP
authors.lastname: Gadelha
authors.forename: Marcelo Valle
authors.initials: MV
authors.lastname: de Sousa
authors.forename: Carlos André Ornela
authors.initials: CA
authors.lastname: Ricart
authors.forename: Belchor
authors.initials: B
authors.lastname: Fontes
authors.forename: Wagner
authors.initials: W
authors.lastname: Fontes
mesh_terms: D000328:Adult; D030562:Databases, Protein; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D009504:Neutrophils / Q000737:chemistry* / Q000378:metabolism; D010449:Peptide Mapping; D020543:Proteome / Q000032:analysis*
chemical_list: D020543:Proteome