title: Probiotics and their potential health claims.
abstract: Many studies have attempted to identify specific positive health effects of probiotics. One of the challenges in generalizing health effects of probiotics is that different strains exert disparate effects on human health. As a result, the efficacy of one strain or species cannot necessarily be inferred from another. The objective of this review is to examine the current scientific literature that could be used as the basis for potential health claims. More specifically, this paper will review existing evidence of different probiotic strains to prevent and treat diarrhea, treat irritable bowel syndrome (IBS), treat inflammatory bowel disease, and prevent colon cancer. The strongest evidence is related to the use of Lactobacillus rhamnosus GG in the prevention and treatment of rotavirus-associated diarrhea. Further examination of the literature also shows promise in the treatment of some forms of IBS with probiotics. Future studies that use consistent supplementation regimes will allow more definitive conclusions to be drawn on the effects of probiotics on IBS, inflammatory bowel disease, and colon cancer.
authors.affiliation: School of Dietetics and Human Nutrition, McGill University, Ste Anne-de-Bellevue, Québec, Canada.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Santosa
authors.forename: Edward
authors.initials: E
authors.lastname: Farnworth
authors.forename: Peter J H
authors.initials: PJ
authors.lastname: Jones
mesh_terms: D003110:Colonic Neoplasms / Q000517:prevention & control*; D019317:Evidence-Based Medicine; D005516:Food Microbiology; D058870:Food, Organic; D005767:Gastrointestinal Diseases / Q000188:drug therapy*; D006801:Humans; D007422:Intestines / Q000382:microbiology; D052201:Lacticaseibacillus rhamnosus / Q000254:growth & development*; D019936:Probiotics / Q000627:therapeutic use