title: Set shifting deficits in melancholic vs. non-melancholic depression: preliminary findings.
abstract: Twenty-two patients with major depressive disorder, 11 of them with melancholic features, and 11 controls were investigated with CANTAB subtests focusing in visual memory/learning and executive functions. Melancholic patients performed worse than the other groups in all tasks and manifested a significant impairment in set shifting. The results are discussed in association with prefrontal dysfunction.
authors.affiliation: 2nd Department of Psychiatry, Athens University Medical School, Attikon General Hospital, 1 Rimini Street, 124 62 Athens, Greece. panpsyclin@attikonhospital.gr
authors.forename: I
authors.initials: I
authors.lastname: Michopoulos
authors.forename: I M
authors.initials: IM
authors.lastname: Zervas
authors.forename: V M
authors.initials: VM
authors.lastname: Papakosta
authors.forename: E
authors.initials: E
authors.lastname: Tsaltas
authors.forename: C
authors.initials: C
authors.lastname: Papageorgiou
authors.forename: T
authors.initials: T
authors.lastname: Manessi
authors.forename: Y G
authors.initials: YG
authors.lastname: Papakostas
authors.forename: L
authors.initials: L
authors.lastname: Lykouras
authors.forename: C R
authors.initials: CR
authors.lastname: Soldatos
mesh_terms: D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003710:Demography; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D007859:Learning Disabilities / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires