title: Psychosis following acute Sydenham's chorea.
abstract: Sydenham's chorea (SC) is characterized by motor, mainly choreic involuntary movements, and psychiatric symptoms, including anxiety, depression, obsessive-compulsive and attention-deficit/hyperactivity disorders. Symptoms of SC may be considered as the result of basal ganglia dysfunction determined by autoimmune mechanisms elicited by streptococcal infection. We report on a case of a 13-year-old boy with brief psychotic episode following acute SC. His hallucinations and delusions remitted after treatment with risperidone, paralleling motor improvement. The neurobiological basis of psychotic symptoms remains largely elusive. This case report provides further insight about the involvement of basal ganglia dysfunction on psychosis.
authors.affiliation: Dept. of Internal Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil. altexr@gmail.com
authors.forename: Antônio Lúcio
authors.initials: AL
authors.lastname: Teixeira
authors.forename: Débora Palma
authors.initials: DP
authors.lastname: Maia
authors.forename: Francisco
authors.initials: F
authors.lastname: Cardoso
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002819:Chorea / Q000150:complications / Q000188:drug therapy / Q000523:psychology*; D005239:Fear; D006212:Hallucinations; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications; D011618:Psychotic Disorders / Q000209:etiology*; D018967:Risperidone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone