title: Intrathecal catheters with subcutaneous port systems in patients with severe cancer-related pain managed out of hospital: the risk of infection.
abstract: Intrathecal catheters have been used for many years to treat severe pain resistant to conventional treatment modalities. Previous studies have found a rate of serious infection of 2%-3% using these catheters in home situations. However, many authors used prophylactic antibiotics routinely in this group of patients, which are both costly and associated with a risk of developing antibiotic resistance. We were interested in studying whether improved hygiene during insertion and care of these catheters in the hospice or home environment would reduce the incidence of catheter-related infections. The results show that prophylactic antibiotic is not necessary, but a careful handling of the system with aseptic technique is important. The infections we registered appeared more than 2 weeks after insertion of the catheters. We now use this method routinely when inserting an intrathecal catheter with a subcutaneous port.
authors.affiliation: Department of Anesthesiology, Orebro University Hospital, Orebro, Sweden. anette.holmfred@orebroll.se
authors.forename: Anette
authors.initials: A
authors.lastname: Holmfred
authors.forename: Thomas
authors.initials: T
authors.lastname: Vikerfors
authors.forename: Lars
authors.initials: L
authors.lastname: Berggren
authors.forename: Anil
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000700:Analgesics / Q000008:administration & dosage; D002404:Catheterization / Q000379:methods*; D015331:Cohort Studies; D020802:Epidural Abscess / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015918:Infusion Pumps, Implantable; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D017192:Skin Diseases, Bacterial / Q000453:epidemiology*
chemical_list: D000700:Analgesics