A phenol quaternary ammonium porphyrin as a potent telomerase inhibitor by selective interaction with quadruplex DNA.
Wang
Ping
P
College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072 (P. R. of China).
Ren
Lige
L
He
Hanping
H
Liang
Feng
F
Zhou
Xiang
X
Tan
Zheng
Z
D004247:DNA / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D054856:G-Quadruplexes; D008968:Molecular Conformation; D019800:Phenol / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*; D020349:Surface Plasmon Resonance; D019914:Taq Polymerase / Q000378:metabolism; D019098:Telomerase / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004791:Enzyme Inhibitors; D011166:Porphyrins; D019800:Phenol; D004247:DNA; D019914:Taq Polymerase; D019098:Telomerase