Response of cluster headache to psilocybin and LSD.
The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on the effects of psilocybin and LSD on cluster headache may be warranted.
Sewell
R Andrew
RA
Clinical Research Laboratory, Alcohol and Drug Abuse Research Center, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA. asewell@mclean.harvard.edu
Halpern
John H
JH
Pope
Harrison G
HG
D000328:Adult; D003027:Cluster Headache / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006213:Hallucinogens / Q000627:therapeutic use; D006801:Humans; D008238:Lysergic Acid Diethylamide / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011562:Psilocybin / Q000627:therapeutic use*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
D006213:Hallucinogens; D011562:Psilocybin; D008238:Lysergic Acid Diethylamide