title: Surgical management of tuberculum sellae meningioma: role of selective extradural anterior clinoidectomy.
abstract: A retrospective analysis of 32 patients with tuberculum sellae meningiomas who underwent surgery via a unilateral pterional approach was performed. A selective extradural anterior clinoidectomy (SEAC) technique was added in 20 patients. All patients had visual dysfunction preoperatively. Macroscopically complete removal with Simpson grade II was performed in 28 patients (87.5%). The postoperative visual function improved in 25 (78.1%), did not change in 3 (9.4%), and worsened in 4 patients (12.5%). The SEAC technique was effective, especially for removal of the tumour extending into the sellae/pituitary stalk (9 patients), the optic canal (4 patients) and hypothalamus (4 patients) with preservation of the visual and endocrinological function. These results were superior to those of surgery without SEAC technique. This technique is therefore recommended for complete resection of the tuberculum sellae meningiomas extending to the surrounding anatomical structures as the SEAC procedure reduces the risk of intraoperative optic nerve injury considerably.
authors.affiliation: Department of Neurosurgery, University Hospital of Zurich, Zurich, Switzerland.
authors.forename: Naoki
authors.initials: N
authors.lastname: Otani
authors.forename: Carl
authors.initials: C
authors.lastname: Muroi
authors.forename: Hirohito
authors.initials: H
authors.lastname: Yano
authors.forename: Nadia
authors.initials: N
authors.lastname: Khan
authors.forename: Athina
authors.initials: A
authors.lastname: Pangalu
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yonekawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000601:surgery*; D008579:Meningioma / Q000150:complications / Q000601:surgery*; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000209:etiology / Q000601:surgery*; D019635:Neurosurgical Procedures / Q000379:methods; D012189:Retrospective Studies; D012658:Sella Turcica / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology / Q000601:surgery*