title: Early vitrectomy for fundus-obscuring dense vitreous haemorrhage from presumptive retinal tears.
abstract: BACKGROUND
  Published literature on the management of patients with fundus-obscuring dense vitreous haemorrhage due to presumptive retinal tears is sparse and advocates waiting for spontaneous resolution. Surgery is indicated only when a definite retinal tear or retinal detachment is identified.
  
  
  METHODS
  A retrospective review of all patients who underwent early vitrectomy for vitreous haemorrhage associated with posterior vitreous detachment was carried out. A comparison of initial visual acuity versus final visual acuity after vitrectomy was performed. The number of eyes that were found to have retinal tears and retinal detachment were documented. Initial and final Snellen acuities were used for statistical analysis. Categorical data were analysed using Fisher's exact test and statistical significance was considered to be p < 0.05.
  
  
  RESULTS
  Sixteen eyes were identified and all these patients presented or were referred soon after the onset of vitreous haemorrhage. Associated ocular pathology (choroidal neovascular membrane, retinal branch vein occlu-sion, macroaneurysm) was suspected to be the source of the haemorrhage in 4 eyes. Vitrectomy was carried out in 12 eyes soon after presentation (mean time 6.3 days, range 1-28 days). Nineteen retinal breaks were seen in these eyes and 5 eyes had more than two breaks. None of the eyes were found to have proliferative vitreoretinopathy at the time of surgery. Two eyes needed repeat surgery for new retinal breaks. Excluding the eyes found to have an ocular pathology as the cause of vitreous haemorrhage, the mean visual acuity improved from hand movements to 6/12 (p < 0.001).
  
  
  CONCLUSIONS
  Early vitrectomy for spontaneous dense fundus-obscuring vitreous haemorrhage and posterior vitreous detachment is safe. Since the number of patients in this study was small, a prospective randomised controlled study comparing early versus late vitrectomy is needed to see whether early surgery also prevents proliferative vitreoretinopathy formation.
authors.affiliation: Cardiff Eye Unit, University Hospital of Wales, Cardiff, UK. ndhingra@doctors.org.uk
authors.forename: Narendra
authors.initials: N
authors.lastname: Dhingra
authors.forename: Ian
authors.initials: I
authors.lastname: Pearce
authors.forename: David
authors.initials: D
authors.lastname: Wong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003452:Cryosurgery; D005260:Female; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity; D014821:Vitrectomy; D020255:Vitreous Detachment / Q000209:etiology / Q000601:surgery; D014823:Vitreous Hemorrhage / Q000209:etiology / Q000601:surgery*
chemical_list: D012827:Silicone Oils