title: Learning curve for add-on stereotactic core needle breast biopsy.
abstract: OBJECTIVE
  To evaluate the learning curve for an add-on 14 G stereotactic core needle biopsy (SCNB).
  
  
  METHODS
  A total of 231 non-palpable breast lesions that had undergone add-on SCNB were evaluated in this prospective study. Five radiologists performed their first three biopsies under supervision. Subsequent, independently performed, biopsies were also evaluated. The samples were collected in three different containers: the first sample in container A, the second and third samples in container B, and subsequent samples in container C (available for four radiologists from the first biopsy on). Technically successful biopsies and false-negative rate in three container combinations (A, A+B, A+B+C) were reported as a function of operator experience.
  
  
  RESULTS
  Technically unsuccessful biopsies occurred significantly more often in microcalcifications than in masses (14.9% versus 3.8%; P=0.04). For microcalcifications, the rate of successful biopsies was 75% (18/24) for the first 5 biopsies and 87.8% (79/90) for the subsequent biopsies (P=0.335); rates for the masses were 95.7% (22/23) and 96.3% (79/82) (P=1.0), respectively. A tendency was noted for the false-negative rate to be higher for the first five biopsies in three container combinations than in subsequent cases.
  
  
  CONCLUSIONS
  Our results support the existence of a learning curve, especially in the biopsy of microcalcifications. More than three mentor-guided biopsies are needed.
authors.affiliation: Department of Clinical Radiology, Kuopio University Hospital and Kuopio University, Kuopio, Finland. Anna.Koskela@kuh.fi
authors.forename: A
authors.initials: A
authors.lastname: Koskela
authors.forename: M
authors.initials: M
authors.lastname: Berg
authors.forename: M
authors.initials: M
authors.lastname: Sudah
authors.forename: A
authors.initials: A
authors.lastname: Malinen
authors.forename: V
authors.initials: V
authors.lastname: Kärjä
authors.forename: P
authors.initials: P
authors.lastname: Mustonen
authors.forename: V
authors.initials: V
authors.lastname: Kataja
authors.forename: S
authors.initials: S
authors.lastname: Soimakallio
authors.forename: R
authors.initials: R
authors.lastname: Vanninen
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D002114:Calcinosis; D005189:False Positive Reactions; D006801:Humans; D011446:Prospective Studies