title: Acute osteomyelitis in congenital hypofibrinogenemia.
abstract: A 10-month-old female child presented with intermittent high grade fever, pain and diffuse swelling in the left knee joint with history of ecchymosis in different areas of the body. There was radiological features of acute osteomyelitis, low fibrinogen level and bacteremia due to the presence of coagulase positive staphylococcus aureus. The child responded nicely to the treatment for acute osteomyelitis and congenital hypofibrinogenemia. So, in congenital hypofibrinogenemia, a joint swelling might be a resultant of an acute osteomyelitis, not mere hemarthrosis.
authors.affiliation: Midnapore Medical College, Paschim Medinipur, West Bengal. himadreedatta@yahoo.com
authors.forename: Sumana
authors.initials: S
authors.lastname: Datta Kanjilal
authors.forename: S
authors.initials: S
authors.lastname: Bagchi
mesh_terms: D000208:Acute Disease; D000347:Afibrinogenemia / Q000150:complications* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005169:Factor VIII / Q000627:therapeutic use; D005260:Female; D005340:Fibrinogen / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents; C026912:cryoprecipitate coagulum; D005169:Factor VIII; D005340:Fibrinogen