Interaction between ocular stabilization reflexes in patients with whiplash injury.
OBJECTIVE
In the past few decades, the automobile has become an increasingly more popular means of transport, which has led to an increasing number of rear-end collisions and consequently has resulted in more patients with whiplash-associated disorders (WADs). Recently, it was found that the gain of one of the ocular stabilization reflexes-the cervico-ocular reflex (COR)-is elevated in patients with whiplash injury. The COR responds to proprioceptive signals from the neck and acts in conjunction with the vestibulo-ocular reflex (VOR) and the optokinetic reflex (OKR) to preserve stable vision on the retina during head motion. Therefore, an investigation was conducted to determine whether the reported elevation of the COR in WADs is accompanied by changes in VOR or OKR.


METHODS
Eye movements of 13 patients and 18 age-matched healthy controls were recorded with an infrared eye-tracking device.


RESULTS
Analysis confirmed a significant increase in COR gain in whiplash patients. Meanwhile the VOR and OKR gains remained the same. No correlation was found between the gains of the reflexes in individual patients. This is in contrast to earlier observations in elderly subjects and subjects with labyrinthine defects, who showed increases in COR gain and decreases in VOR gain.


CONCLUSIONS
Impaired neck motion, altered proprioception of the neck, or disorganization in the process of VOR plasticity could explain the lack of change in VOR gain.
Montfoort
Inger
I
Department of Neuroscience, Erasmus MC Rotterdam, The Netherlands. i.montfoort@erasmusmc.nl
Kelders
Willem P A
WP
van der Geest
Jos N
JN
Schipper
Inger B
IB
Feenstra
Louw
L
de Zeeuw
Chris I
CI
Frens
Maarten A
MA
D000328:Adult; D005133:Eye Movements; D019416:Head Movements / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009334:Neck Muscles / Q000502:physiology*; D009801:Oculomotor Muscles / Q000502:physiology*; D011434:Proprioception / Q000502:physiology; D012018:Reflex / Q000502:physiology*; D014911:Whiplash Injuries / Q000503:physiopathology*