Freeze-thawing of breast milk does not prevent cytomegalovirus transmission to a preterm infant.
Freezing human milk is recommended to inactivate cytomegalovirus (CMV). A case of a preterm infant exclusively receiving frozen breast milk from his CMV seropositive mother showed that storage of breast milk for two months at -20 degrees C did not prevent symptomatic postnatal CMV infection.
Maschmann
J
J
Children's Hospital, University of Würzburg, Josef-Schneider-Str 2, 97080 Würzburg, Germany. jens.maschmann@mail.uni-wuerzburg.de
Hamprecht
K
K
Weissbrich
B
B
Dietz
K
K
Jahn
G
G
Speer
C P
CP
D015925:Cryopreservation; D003586:Cytomegalovirus Infections / Q000517:prevention & control / Q000635:transmission*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D008297:Male; D008895:Milk, Human / Q000821:virology*