title: Antimicrobial activity of coupled hydroxyanthracenones isolated from plants of the genus Karwinskia.
abstract: The in vitro activity of some isolated hydroxyanthracenones belonging to the genus Karwinskia against four bacteria, six filamentous fungi and four yeast are reported. These hydroxyanthracenones were found to possess antimicrobial activity, particularly against Streptococcus pyogenes, Candida albicans, C. boidinii, C. glabrata and Cryptococcus neoformans; minimal inhibitory concentrations range between 16 and 2 microg/ml.
authors.affiliation: Departamento de Química Analítica, Madero y Aguirre Pequeño, Colonia Mitras Centro, Monterrey, Nuevo León, CP 64460, Mexico.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Salazar
authors.forename: Verónica
authors.initials: V
authors.lastname: Rivas
authors.forename: Gloria
authors.initials: G
authors.lastname: González
authors.forename: Noemí
authors.initials: N
authors.lastname: Waksman
mesh_terms: D000873:Anthracenes / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000032:analysis*; D000935:Antifungal Agents / Q000032:analysis*; D031956:Karwinskia / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure
chemical_list: D000873:Anthracenes; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents