title: Microbial adhesion to zirconium alloys.
abstract: We present data and analyses concerning the adhesion of clinically relevant Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa (bacteria) and Candida albicans (yeast) to Zircaloy-2 (Zry-2) and Zircadyne-705 (Zr705) surfaces. These zirconium-based materials are similar to those now being used in total hip and knee replacements. Here we study clinical strains of microbes under shaken and stationary exposure conditions, and their ability to adhere to Zr surfaces having different oxide thicknesses. We use X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), viable counts, endotoxin assays, and statistical analysis methods, and demonstrate a predictive model for microbial adhesion based on XPS data.
authors.affiliation: Department of Physics, The University of Akron, Akron, OH 44325, United States.
authors.forename: J D
authors.initials: JD
authors.lastname: Ehrman
authors.forename: E T
authors.initials: ET
authors.lastname: Bender
authors.forename: N
authors.initials: N
authors.lastname: Stojilovic
authors.forename: T
authors.initials: T
authors.lastname: Sullivan
authors.forename: R D
authors.initials: RD
authors.lastname: Ramsier
authors.forename: B W
authors.initials: BW
authors.lastname: Buczynski
authors.forename: M M
authors.initials: MM
authors.lastname: Kory
authors.forename: R P
authors.initials: RP
authors.lastname: Steiner
mesh_terms: D000497:Alloys; D001422:Bacterial Adhesion; D002176:Candida albicans / Q000502:physiology; D002448:Cell Adhesion; D020099:Coated Materials, Biocompatible; D015169:Colony Count, Microbial; D004731:Endotoxins / Q000032:analysis; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D011550:Pseudomonas aeruginosa / Q000502:physiology; D013057:Spectrum Analysis; D013211:Staphylococcus aureus / Q000502:physiology; D013212:Staphylococcus epidermidis / Q000502:physiology; D013499:Surface Properties; D014965:X-Rays; D015040:Zirconium
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D004731:Endotoxins; D015040:Zirconium