Renal impairment after living donor liver transplantation.
BACKGROUND
There are few reports of postoperative renal impairment after living donor liver transplantation (LDLT).


METHODS
We reviewed 246 LDLT recipients to examine the effects of postoperative renal impairment on the results of LDLT.


RESULTS
The incidence of renal impairment and the requirements for postoperative renal replacement therapy were 29% and 9%, respectively. Intraoperative blood loss (P<.0001) and preoperative serum creatinine (P=.0002) were significant independent risk factors for the development of early renal dysfunction. Patients who required renal replacement therapy had a lower survival rate (P=.01).


CONCLUSIONS
We identified the risk factors for postoperative renal impairment, providing useful metrics to establish a treatment strategy for high risk liver transplant patients.
Akamatsu
N
N
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.
Sugawara
Y
Y
Tamura
S
S
Kakeno
J
J
Togashi
J
J
Makuuchi
M
M
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan; D007674:Kidney Diseases / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D016031:Liver Transplantation / Q000401:mortality; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*; D017582:Renal Replacement Therapy; D012189:Retrospective Studies; D016019:Survival Analysis