title: A facile synthesis of 1,6-dideoxynojirimycin from L-sorbose.
abstract: A practical synthesis of 1,6-dideoxynojirimycin, a potent glycosidase inhibitor, starting from L-sorbose, is described.
authors.affiliation: Department of Chemical Biology, School of Pharmaceutical Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
authors.forename: Jia-Ning
authors.initials: JN
authors.lastname: An
authors.forename: Xiang-Bao
authors.initials: XB
authors.lastname: Meng
authors.forename: Yun
authors.initials: Y
authors.lastname: Yao
authors.forename: Zhong-Jun
authors.initials: ZJ
authors.lastname: Li
mesh_terms: D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D005959:Glucosidases / Q000037:antagonists & inhibitors; D008956:Models, Chemical; D015394:Molecular Structure; D013013:Sorbose / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C513752:1,6-dideoxynojirimycin; D004791:Enzyme Inhibitors; D017485:1-Deoxynojirimycin; D005959:Glucosidases; D013013:Sorbose