title: Applications of asymmetric hydrosilylations mediated by catalytic (DTBM-SEGPHOS)CuH.
abstract: [reaction: see text] Several aryl ketone precursors useful in the synthesis of known physiologically active compounds have been reduced to the corresponding nonracemic alcohols. The previously reported combination of a catalytic quantity of (R)-(-)-DTBM-SEGPHOS-ligated CuH and stoichiometric PMHS is shown to be very effective in these asymmetric hydrosilylations.
authors.affiliation: Department of Chemistry & Biochemistry, University of California, Santa Barbara, 93106, USA. lipshutz@chem.ucsb.edu
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
authors.forename: Asher
authors.initials: A
authors.lastname: Lower
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Kucejko
authors.forename: Kevin
authors.initials: K
authors.lastname: Noson