Two new benzylbenzoate glucosides from Curculigo orchioides.
An extract from in vitro cultures of Curculigo orchioides grown as bulbils in shake flasks, afforded two new glucosides of substituted benzylbenzoate - curculigoside C (3) and curculigoside D (4) - together with two known compounds - curculigoside A (1) and curculigoside B (2). Their structures were elucidated on the basis of spectral evidence, in particular by using 2D NMR methods. Their vasoactive properties were assessed in isolated rat aortic rings.
Valls
Josep
J
Groupe d'Etude des Substances Naturelles à Activités Biologiques, EA 3675, Université de Bordeaux 2, Bordeaux, France.
Richard
Tristan
T
Larronde
Fabienne
F
Leblais
Véronique
V
Muller
Bernard
B
Delaunay
Jean-Claude
JC
Monti
Jean-Pierre
JP
Ramawat
K G
KG
Mérillon
Jean-Michel
JM
D000818:Animals; D001011:Aorta / Q000187:drug effects; D001593:Benzyl Compounds / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D031408:Curculigo; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects; D005960:Glucosides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D014661:Vasoconstriction / Q000187:drug effects*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use
D001593:Benzyl Compounds; D005960:Glucosides; D010936:Plant Extracts; D014662:Vasoconstrictor Agents