Epidermoid cyst with infiltrative malignant melanoma in the cerebellopontine angle.
We report a patient with an intracranial epidermoid cyst associated with malignant melanoma in the cerebellopontine angle. The CT, MRI and histopathological findings showed an intracranial epidermoid cyst with an adjacent infiltrating melanoma. Immunohistochemical staining of the solid tumour was positive for the melanoma marker HMB45 and negative for GFAP and cytokeratin. Both CT and MRI were helpful in this patient but the diagnosis could only be made on histopathology.
Meng
Fan-gang
FG
Department of Neurosurgery, QiLu Hospital Shandong University, Ji'nan, Shandong Province, 250012, People's Republic of China.
Wu
Cheng-yuan
CY
Liu
Zhao-hua
ZH
Zhu
Shu-gan
SG
Liu
Yu-guang
YG
D002526:Cerebellar Diseases / Q000150:complications / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000150:complications / Q000473:pathology*; D002530:Cerebellopontine Angle; D004814:Epidermal Cyst / Q000150:complications / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008545:Melanoma / Q000150:complications / Q000473:pathology*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods