title: Fusarium oxysporum pneumonia in an immunocompetent host.
abstract: A case of symptomatic pulmonary infection caused by Fusarium oxysporum occurred in a woman after she had cleaned out bird droppings from a boat house. She was also a gardener who had mild, chronic obstructive lung disease, but who had no evidence of systemic immunosuppression. She was treated with oral voriconazole for four months and had marked clinical improvement and mycological cure. To the best of our knowledge, this is the first reported case of isolated pulmonary fusariosis in an apparently immunocompetent person. Oral voriconazole therapy was effective in this clinical setting.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA. stephen.r.gorman@lahey.org
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Gorman
authors.forename: Anna-Pelagia
authors.initials: AP
authors.lastname: Magiorakos
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Zimmerman
authors.forename: Donald E
authors.initials: DE
authors.lastname: Craven
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001999:Bronchoscopy; D005260:Female; D005670:Fusarium; D006801:Humans; D007121:Immunocompetence; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy; D011014:Pneumonia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D011743:Pyrimidines / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole