title: Case report: Hepatitis A preceding Guillain-Barré syndrome.
abstract: A case of acute hepatitis A with Guillain-Barré Syndrome subtype AMAN (acute motor axonal neuropathy) in a 17-year-old male is reported. Serum and cerebrospinal fluid were positive for anti-hepatitis A virus (HAV) IgM, IgG, and IgA. The onset of the syndrome was evident in week 3 of illness. The remarkably high titers of serum anti-HAV IgG appeared unique to a hepatitis A patient with the syndrome. Phylogenetic analysis of the HAV genome detected in the serum and feces revealed genotype IIIA, circulating commonly in Pune, western India.
authors.affiliation: National Institute of Virology, Pune, Maharashtra, India. chitambars@hotmail.com
authors.forename: Shobha D
authors.initials: SD
authors.lastname: Chitambar
authors.forename: Rahul S
authors.initials: RS
authors.lastname: Fadnis
authors.forename: Madhuri S
authors.initials: MS
authors.lastname: Joshi
authors.forename: A
authors.initials: A
authors.lastname: Habbu
authors.forename: S G
authors.initials: SG
authors.lastname: Bhatia
mesh_terms: D000293:Adolescent; D020275:Guillain-Barre Syndrome / Q000150:complications*; D006506:Hepatitis A / Q000150:complications*; D035922:Hepatitis A Antibodies / Q000097:blood; D030041:Hepatitis A virus / Q000235:genetics; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D012367:RNA, Viral; D013997:Time Factors
chemical_list: D035922:Hepatitis A Antibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012367:RNA, Viral