[Prevalence of hepatitis C virus infection among haematological and oncological patients treated with blood products].
The aim of our study was to determine prevalence of hepatitis C virus infection (HCV) among patients with haematological and oncological diseases treated in the past with blood or blood products (about 20% among adults and about 50% in children in selected wards in 1992). Infection with HCV was detected in 3 out of 64 examined patients (4.7%) and in 64 of 14 098 blood donors (0.4%), p < 0.05. The two HCV cases in the study group were in persons with haemophilia A treated with cryoprecipitate before 1992. Among 51 persons receiving transfusions only after 1992--1 case of HCV infection was detected (2.0%) Our results indicate improvement in the safety of treatment with blood and/or blood products and suggest that the present risk of HCV infection among patients with haematological and oncological diseases treated with these products after 1992 is rather small.
Chlabicz
Sławomir
S
Zakład Medycyny Rodzinnej i Pielegniarstwa, Srodowiskowego Akademii Medycznej w Białymstoku.
Sawicka-Powierza
Jolanta
J
Kovalchuk
Oksana
O
Kłoczko
Janusz
J
Radziwon
Piotr
P
Wojtukiewicz
Marek
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016913:Blood Component Transfusion / Q000009:adverse effects / Q000706:statistics & numerical data*; D015984:Causality; D015897:Comorbidity; D003428:Cross Infection / Q000453:epidemiology / Q000635:transmission; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology* / Q000635:transmission*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014766:Viremia / Q000097:blood / Q000453:epidemiology* / Q000635:transmission*