Health-related quality of life of HIV-infected children on complex antiretroviral therapy at home.
The study describes quality of life as perceived by parents and measured by the Child Health Questionnaire (CHQ-28) for a convenience sample of 33 HIV-infected children age 5 to 18 years cared for at home on complex antiretroviral drug regimens. When compared with normative data on healthy U.S. children, parent reports for the HIV-infected children did not differ significantly on the following CHQ concepts: role/social related to emotional, behavioral or physical problems; bodily pain; behavior; mental health; self-esteem; impact on parental time; family activities; and family cohesion. Parents perceived their children to be functioning at a level significantly lower than the norm in general health (t -6.47, p = .000), physical functioning (t -2.37, p = .024), and physical summary (t -3.80, p = .001). Parental impact-emotional was impressively higher than the norm (t -3.74, p = .001). Differences were independent of gender, primary language, ethnicity, and Centers for Disease Control and Prevention clinical classifications for pediatric HIV disease.
Byrne
Mary Woods
MW
Columbia University School of Nursing, USA.
Honig
Judy
J
D000223:Adaptation, Psychological; D000293:Adolescent; D023241:Antiretroviral Therapy, Highly Active; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008297:Male; D009511:New England; D002666:Psychology, Child; D011788:Quality of Life