title: Enantioselective synthesis of bridged- or fused-ring bicyclic ketones by a catalytic asymmetric Michael addition pathway.
abstract: Efficient methodology has been developed for the conjugate addition of ketene acetals to cyclic alpha,beta-enones. The chiral adducts allow access to fused- or bridged-ring structures such as those shown.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
authors.forename: Duan
authors.initials: D
authors.lastname: Liu
authors.forename: Sungwoo
authors.initials: S
authors.lastname: Hong
authors.forename: E J
authors.initials: EJ
authors.lastname: Corey