title: Treatment of premature ejaculation.
abstract: Premature ejaculation (PE) is a common problem, the treatment of which has received an increasing interest in recent years. Traditional management continues to be psychotherapy, with techniques such as the 'squeeze' and 'stop-start' most commonly employed. The application of local anaesthetics to the glans to delay ejaculation, first described over 60 years ago, continues to be used both in medical practice and as an 'over-the-counter' remedy. Over the years, a variety of psychopharmacological agents, especially antidepressants, have been described as treatments for PE. At the present time, the selective serotonin re-uptake inhibitors, licensed for other indications, emerge as the most effective agents to delay ejaculation, but none are licensed for the treatment of PE. There appears to be a high relapse rate irrespective of the mode of therapy used.
authors.affiliation: Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, UK. alanriley@doctors.org.uk
authors.forename: A
authors.initials: A
authors.lastname: Riley
authors.forename: R T
authors.initials: RT
authors.lastname: Segraves
mesh_terms: D000779:Anesthetics, Local / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002755:Choice Behavior; D004542:Ejaculation; D006801:Humans; D008297:Male; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use; D011613:Psychotherapy / Q000379:methods; D012648:Self Care; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012735:Sexual Dysfunction, Physiological / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D000928:Antidepressive Agents; D010726:Phosphodiesterase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors