Styryl molecules light-up RNAs.
A combinatorial library of 1336 fluorescent styryl molecules was synthesized aiming to select dyes that are photostable, non-toxic, and specific for RNA molecules in living cells . These dyes are potentially important to the study of gene expression in live cells.
Dirks
Roeland W
RW
Department of Molecular Cell Biology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
Tanke
Hans J
HJ
D000818:Animals; D005456:Fluorescent Dyes / Q000737:chemistry; D012313:RNA / Q000235:genetics*; D015347:RNA Probes / Q000737:chemistry* / Q000235:genetics*
D005456:Fluorescent Dyes; D015347:RNA Probes; D012313:RNA