Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.
OBJECTIVE
To evaluate the surgical treatment, we investigated that performed for chronic pancreatitis patients suffering from severe pain resistant to conservative treatments.


METHODS
Nineteen chronic pancreatitis patients with severe pain resistant for a long time to previous conservative medical and/or interventional treatments underwent surgery retrospectively. We evaluated a difference of postoperative improvement of symptoms in patients with surgical treatment including nerve plexus resection.


RESULTS
The mean follow-up interval after surgery was 59.7 months (range, 3.0-187.3 months). Of 19 patients, 14 (73.7%) underwent nerve plexus resection. Relief of symptoms was observed in 16 of 19 patients (84.2%). Fourteen of the 15 patients (93.3%) in the nerve plexus resection group were relieved of symptoms after surgery, compared to only two of four (50.0%) patients in the nerve plexus non-resection group.


CONCLUSIONS
Surgical treatments with nerve plexus resection appropriately matched with individual patients are very safe and contribute to the improvement of the quality of life for chronic pancreatitis patients resistant to conservative treatments.
Sawai
Hirozumi
H
Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku Nagoya 4678601, Japan. cb8h-swi@asahi-net.or.jp
Okada
Yuji
Y
Funahashi
Hitoshi
H
Matsuo
Yoichi
Y
Yamamoto
Minoru
M
Tanaka
Moritsugu
M
Takeyama
Hiromitsu
H
Manabe
Tadao
T
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D019299:Decompression, Surgical; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010148:Intractable Pain / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D010179:Pancreas / Q000000981:diagnostic imaging* / Q000294:innervation* / Q000601:surgery; D010180:Pancreatectomy; D010183:Pancreatic Ducts / Q000601:surgery; D016577:Pancreaticoduodenectomy; D010193:Pancreaticojejunostomy; D050500:Pancreatitis, Chronic / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D010525:Peripheral Nerves / Q000601:surgery*; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome
D000700:Analgesics