Adenovirus infections in transplant recipients.
Adenoviruses are increasingly recognized as contributors to morbidity and mortality among stem cell and solid-organ transplant recipients. Clinical presentations range from asymptomatic viremia to respiratory and gastrointestinal disease, hemorrhagic cystitis, and severe disseminated illness. The limited clinical data available support the use of cidofovir for many of these illnesses. Prospective studies are needed to better understand the pathogenesis of and therapeutic options for adenoviral infections in this patient population.
Ison
Michael G
MG
Division of Infectious Diseases, Transplant Infectious Diseases Service, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. mgison@alumni.grinnell.edu
D000256:Adenoviridae / Q000145:classification* / Q000235:genetics; D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D000998:Antiviral Agents / Q000627:therapeutic use*; D006801:Humans; D014180:Transplantation
D000998:Antiviral Agents