title: Celiac disease and childhood cancer.
abstract: Celiac disease is an autoimmune enteropathy developing in genetically predisposed individuals after mucosal contact with gluten, secondary to unknown triggering factors. An increased rate of malignancies in adults with celiac disease has been confirmed in several studies, but there is considerable evidence that a gluten-free diet protects against the development of cancer. The association between celiac disease and childhood cancer is not clear. Few cases are reported in the literature. Here, we report the cases referred to our pediatric oncology unit with a review of the literature.
authors.affiliation: Pediatric Oncology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy. stefanocereda@libero.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Cereda
authors.forename: Graziella
authors.initials: G
authors.lastname: Cefalo
authors.forename: Filippo
authors.initials: F
authors.lastname: Spreafico
authors.forename: Serena
authors.initials: S
authors.lastname: Catania
authors.forename: Cristina
authors.initials: C
authors.lastname: Meazza
authors.forename: Marta
authors.initials: M
authors.lastname: Podda
authors.forename: Monica
authors.initials: M
authors.lastname: Terenziani
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications* / Q000235:genetics; D002446:Celiac Disease / Q000150:complications* / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D004036:Diet, Atherogenic; D005260:Female; D020022:Genetic Predisposition to Disease; D005983:Glutens; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000209:etiology* / Q000235:genetics
chemical_list: D005983:Glutens