title: [Kikuchi-Fujimoto disease: review of four cases].
abstract: Kikuchi-Fujimoto disease is an uncommon form of lymphadenitis, firstly described in Japan. Etiology is unknown. It affects mainly young women. It commonly manifests as a painful cervical lymphadenitis usually associated with fever and leukopenia. Clinical course users to be benign, leading spontaneously to a complete recovery. Histological findings include necrotizing changes with cariorrhesis, partial loss of ganglionar architecture and foci of histiocytic infiltrates in the cortical and/or paracortical zones of the lymph nodes. A common finding is the absence of neutrophil granulocytes in the inflammatory infiltrates, in contrast to other necrotizing lymphadenitis. We report four cases of Kikuchi-Fujimoto disease, recently identified in our hospital.
authors.affiliation: Unidad de Enfermedades Infecciosas, Servicios de Pediatría, Hospital de Cruces, Universidad del País Vasco, 48009 Bilbao. secretaria.infecciosos@hcru.osakidetza.net
authors.forename: M
authors.initials: M
authors.lastname: Montejo
authors.forename: N
authors.initials: N
authors.lastname: Lekerika
authors.forename: I
authors.initials: I
authors.lastname: Astigarraga
authors.forename: K
authors.initials: K
authors.lastname: Aguirrebengoa
authors.forename: J
authors.initials: J
authors.lastname: Goikoetxea
authors.forename: J G
authors.initials: JG
authors.lastname: Erdozain
authors.forename: N
authors.initials: N
authors.lastname: Bidaurrazaga
mesh_terms: D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis*; D006801:Humans; D008297:Male