title: Many roads lead to "auxin": of nitrilases, synthases, and amidases.
abstract: Recent progress in understanding the biosynthesis of the auxin, indole-3-acetic acid (IAA) in Arabidopsis thaliana is reviewed. The current situation is characterized by considerable progress in identifying, at the molecular level and in functional terms, individual reactions of several possible pathways. It is still too early to piece together a complete picture, but it becomes obvious that A. thaliana has multiple pathways of IAA biosynthesis, not all of which may operate at the same time and some only in particular physiological situations. There is growing evidence for the presence of an indoleacetamide pathway to IAA in A. thaliana, hitherto known only from certain plant-associated bacteria, among them the phytopathogen Agrobacterium tumefaciens.
authors.affiliation: Department of Plant Physiology, Ruhr-University Bochum, Universitätsstrasse 150, ND 3/55, 44801 Bochum, Germany. stephan.pollmann@rub.de
authors.forename: S
authors.initials: S
authors.lastname: Pollmann
authors.forename: A
authors.initials: A
authors.lastname: Müller
authors.forename: E W
authors.initials: EW
authors.lastname: Weiler
mesh_terms: D000581:Amidohydrolases / Q000502:physiology; D000619:Aminohydrolases / Q000502:physiology; D017360:Arabidopsis / Q000201:enzymology / Q000378:metabolism*; D007210:Indoleacetic Acids / Q000378:metabolism*; D007211:Indoles / Q000378:metabolism; D009097:Multienzyme Complexes / Q000502:physiology; D010091:Oximes / Q000378:metabolism; D010937:Plant Growth Regulators / Q000378:metabolism*; D014363:Tryptamines / Q000378:metabolism
chemical_list: D007210:Indoleacetic Acids; D007211:Indoles; D009097:Multienzyme Complexes; D010091:Oximes; D010937:Plant Growth Regulators; D014363:Tryptamines; C467098:indole-3-acetaldoxime; C421912:indole-3-acetic acid synthase; C008122:indol-3-yl pyruvic acid; C030737:indoleacetic acid; C015950:indoleacetamide; D000581:Amidohydrolases; D000619:Aminohydrolases; C021867:nitrilase