title: Treating cervical dentin hypersensitivity with fluoride varnish: a randomized clinical study.
abstract: BACKGROUND
  This subject-blind randomized clinical trial tested the efficacy of a new 5 percent sodium fluoride varnish (AllSolutions Fluoride Varnish, Dentsply Professional, York, Pa.) for treatment of cervical dentin hypersensitivity. The authors also compared the test varnish with a control fluoride varnish (Duraphat, Colgate Oral Pharmaceuticals, New York City).
  
  
  METHODS
  The study involved application of the test or control varnish to 19 subjects (59 teeth) with tooth sensitivity. The authors applied each product once to each tooth, following manufacturers' instructions. They used a visual analog scale (VAS) to assess subjects' responses to compressed air and ice stimuli at six weeks before baseline, at baseline and at two, eight and 24 weeks after treatment.
  
  
  RESULTS
  Mean VAS scores for teeth receiving the test varnish dropped from 34.9 (air) and 68.0 (ice) at baseline to 26.3 (air) and 54.7 (ice) at two weeks after treatment. Mean scores at 24 weeks were 20.6 (air) and 34.8 (ice), representing statistically significant differences from baseline values. For the control varnish, mean VAS scores dropped from 36.9 (air) and 64.2 (ice) at baseline to 32.9 (air) and 47.2 (ice) at two weeks, and to 20.8 (air) and 40.3 (ice) at 24 weeks. The authors analyzed the data for statistical significance, accounting for clustering of teeth within subjects.
  
  
  CONCLUSIONS
  The test varnish was effective in reducing cervical dentin hypersensitivity. However, the efficacy was not significantly different from that of the control varnish.
authors.affiliation: Department of Operative Dentistry, The University of North Carolina at Chapel Hill, School of Dentistry, 441 Brauer Hall, CB #7450, 27599-7450, USA. rittera@dentistry.unc.edu
authors.forename: André V
authors.initials: AV
authors.lastname: Ritter
authors.forename: Walter
authors.initials: W
authors.lastname: de L Dias
authors.forename: Patrícia
authors.initials: P
authors.lastname: Miguez
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Caplan
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Swift
mesh_terms: D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D003807:Dentin Sensitivity / Q000188:drug therapy*; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D016037:Single-Blind Method; D012969:Sodium Fluoride / Q000627:therapeutic use*; D019237:Tooth Cervix; D016896:Treatment Outcome
chemical_list: C514043:AllSolutions Fluoride Varnish; D005460:Fluorides, Topical; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride