Polyphenol-enriched oolong tea increases fecal lipid excretion.
OBJECTIVE
To assess possibility of polyphenol-enriched oolong tea to reduce dietary lipid absorption in humans.


METHODS
Twelve healthy adult subjects, three males and nine females, aged (mean+/-s.d.) 22.0+/-1.8 years, respectively, were randomly divided into two groups. The participants were followed a double-blind placebo-controlled crossover design, including 7-day washout periods and 10-day treatment periods. During the treatment periods, subjects were given about 38 g of lipids from potato chips (19 g each within 30 min after lunch and dinner) and total 750 ml beverages (placebo- or polyphenol-enriched oolong tea) at three meals. Blood samples were collected for biochemical examination at days 8, 18, 25 and 35 of the study period. On the last 3 days of each treatment period, feces were collected to measure the excretion of lipids.


RESULTS
Lipid excretion into feces was significantly higher in the polyphenol-enriched oolong tea period (19.3+/-12.9 g/3 day) than in the placebo period (9.4+/-7.3 g/3 day) (P < 0.01). Cholesterol excretion tended to increase in polyphenol-enriched oolong tea period (1.8+/-1.2 g/3 day) compared with that of placebo (1.2+/-0.6 g/3 day) (P = 0.056).


CONCLUSIONS
The results of this study indicated that polyphenol-enriched oolong tea could increase lipid excretion into feces when subjects took high-lipid diet.
Hsu
T-F
TF
International Public Health Nutrition, Graduate School of Health Biosciences, The University of Tokushima, Tokushima, Japan.
Kusumoto
A
A
Abe
K
K
Hosoda
K
K
Kiso
Y
Y
Wang
M-F
MF
Yamamoto
S
S
D000328:Adult; D002784:Cholesterol / Q000032:analysis / Q000378:metabolism; D018592:Cross-Over Studies; D004041:Dietary Fats / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004311:Double-Blind Method; D005243:Feces / Q000737:chemistry*; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D005527:Food, Fortified; D006801:Humans; D006937:Hypercholesterolemia / Q000178:diet therapy; D007408:Intestinal Absorption / Q000187:drug effects*; D008055:Lipids / Q000032:analysis*; D008297:Male; D009765:Obesity / Q000178:diet therapy; D010636:Phenols / Q000494:pharmacology*; D059808:Polyphenols; D013662:Tea
D004041:Dietary Fats; D005419:Flavonoids; D008055:Lipids; D010636:Phenols; D059808:Polyphenols; D013662:Tea; D002784:Cholesterol