Sarcoidosis presenting with hearing loss and granulomatous interstitial nephritis in an adolescent.
Granulomatous interstitial nephritis is an uncommon finding in a kidney biopsy. The differential diagnosis is broad and includes infections, drug exposure, and sarcoidosis. Sarcoidosis, a systemic disorder of unknown etiology characterized by the presence of noncaseating granulomata in affected organs, is rare in children. We discuss an adolescent boy with the unusual presentation of granulomatous interstitial nephritis and acute deafness. Sarcoidosis should be considered as part of the differential diagnosis for children and adolescents with hearing loss and kidney disease.
Rheault
Michelle N
MN
Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Manivel
Juan C
JC
Levine
Samuel C
SC
Sinaiko
Alan R
AR
D000293:Adolescent; D006099:Granuloma / Q000503:physiopathology*; D034381:Hearing Loss / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000503:physiopathology*; D012507:Sarcoidosis / Q000503:physiopathology*