title: Electrochemical oxidation of morin and interaction with DNA.
abstract: A poly (tetrafluroethylene)-deoxyribonucleate acid (PTFE-DNA) film-modified glassy carbon electrode (GCE) has been fabricated. The electrochemical oxidation behaviors of morin as well as its interaction with DNA have been studied at PTFE-DNA film-modified GCE and bare GCE by electrochemical methods. This modified electrode shows an enhanced effectiveness towards the oxidation of morin. Importantly, as to the interaction between morin and DNA in solution, characteristic parameters such as the binding stoichiometry and association equilibrium constant according to the Hill model for cooperative binding have been determined on the basis of linear sweep voltammetry and chronocoulometry.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Xu
authors.forename: Jia
authors.initials: J
authors.lastname: Zhao
authors.forename: Shengshui
authors.initials: S
authors.lastname: Hu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D017097:Electric Impedance; D004563:Electrochemistry / Q000379:methods*; D005419:Flavonoids / Q000737:chemistry*; D008956:Models, Chemical; D010084:Oxidation-Reduction; D047309:Flavones
chemical_list: D004247:DNA; D005419:Flavonoids; C008548:morin; D047309:Flavones