[Impact of demographic and psychosocial factors on adherence to antiretroviral treatment].
OBJECTIVE
Antiretroviral efficacy is closely related to the degree of adherence. The aim of this study is to assess the association between psychosocial and demographic variables and adherence to antiretroviral treatment.


METHODS
A cross-sectional survey of 320 patients under antiretroviral treatment was conducted in four Andalusian hospitals, using a semi-structured questionnaire given by health care professionals.


RESULTS
Median age was 39.7 years. Nearly 12% of the sample was considered non-compliant to antiretroviral treatment. An interaction was observed between psychological morbidity and mental health quality of life scores. Among patients who presented psychological morbidity, a higher mental quality of life score was associated with a lower risk of non-compliance (P = 0.04). This association was not found among patients without psychological morbidity. Older age, homosexual or bisexual status and the use of injecting drugs for a shorter period of time was associated with non-compliance.


CONCLUSIONS
Demographic and psychological factors have an influence on adherence to antiretroviral treatment.
Ruiz-Pérez
Isabel
I
Escuela Andaluza de Salud Pública, Campus Universitario de Cartuja, Granada, España. isabel.ruiz.easp@juntadeandalucía.es
Olry de Labry-Lima
Antonio
A
Prada-Pardal
José L
JL
Rodríguez-Baño
Jesús
J
Causse-Prados
Manuel
M
López-Ruz
Miguel A
MA
Martín-Rico
Patricia
P
del Arco-Jiménez
Alfonso
A
Pasquau-Liaño
Juan
J
de la Torre-Lima
Javier
J
López-Gómez
Manuel
M
Muñoz-Roca
Nuria
N
Marcos-Herrero
Miguel
M
Muñoz
Isabel
I
Morales-Rojas
Dolores
D
D000328:Adult; D000367:Age Factors; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000523:psychology*; D001727:Bisexuality; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004522:Educational Status; D004651:Employment; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D006716:Homosexuality; D006801:Humans; D008297:Male; D008393:Marriage; D001523:Mental Disorders / Q000453:epidemiology; D008691:Methadone / Q000627:therapeutic use; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data; D011788:Quality of Life; D012306:Risk; D012944:Social Support; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D011795:Surveys and Questionnaires; D019562:Viral Load
D019380:Anti-HIV Agents; D008691:Methadone