title: Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation.
abstract: We describe an infusion of dexmedetomidine at 1.0 microg.kg(-1).min(-1) for 10 min (total dose, 144 microg) sedation in a 3-yr-old child weighing 14 kg. The large dose of dexmedetomidine produced a hemodynamically stable patient who was deeply sedated for approximately 4 h after discontinuing the infusion.
authors.affiliation: Department of Anesthesia and Pediatrics, West Virginia University, 3618 Hsc, PO box 9134, Morgantown, West Virginia 26506-9134, USA. rosend@rcbhsc.wvu.edu
authors.forename: David A
authors.initials: DA
authors.lastname: Rosen
authors.forename: Jason T
authors.initials: JT
authors.lastname: Daume
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage*; D002675:Child, Preschool; D016292:Procedural Sedation; D020927:Dexmedetomidine / Q000008:administration & dosage*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D018810:Magnetic Resonance Angiography; D008297:Male; D015742:Propofol
chemical_list: D000316:Adrenergic alpha-Agonists; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine; D015742:Propofol