title: Use of fibrin glue in fixation of amniotic membranes in sterile corneal ulceration.
abstract: OBJECTIVE
  To describe a method of fibrin glue fixation of single or multilayered amniotic membranes in sterile corneal ulceration.
  
  
  METHODS
  A modified microsurgical procedure.
  
  
  METHODS
  The corneal ulcer is cleaned and the components of fibrin glue are applied separately. Amniotic membranes are rotated through the fibrinogen component and subsequently into the site of the ulceration where thrombin is already applied. An overlay membrane is sutured additionally on top. The results for one patient are illustrated as an example.
  
  
  RESULTS
  The application technique prevents development of foam and leads to a thin fibrin film, which minimizes any irregularities of the fixed membranes and creates extra time to adjust the membranes' position.
  
  
  CONCLUSIONS
  This method presents as an effective procedure for the treatment of sterile corneal ulceration and creates valuable time if any elective corneal graft procedure is required.
authors.affiliation: University Eye Hospital Muenster, Muenster, Germany. uhligc@uni-muenster.de
authors.forename: Constantin E
authors.initials: CE
authors.lastname: Uhlig
authors.forename: Holger
authors.initials: H
authors.lastname: Busse
authors.forename: Markus
authors.initials: M
authors.lastname: Groppe
mesh_terms: D000369:Aged, 80 and over; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D003320:Corneal Ulcer / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives