title: [Clinical course and treatment of patients with differentiated thyroid carcinoma diagnosed during the year 1995].
abstract: The aim of the study was to analyze the clinical course and therapy in patients with differentiated thyroid carcinoma (DTC) diagnosed in Poland within the year 1995. The group of 478 patients with thyroid cancer (57.7% of all thyroid cancer cases diagnosed this year in Poland) was analyzed. Patients were diagnosed or treated in Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch. Detailed analysis was performed in 352 patients with DTC who were treated by surgery. 292 patients (60%) received adjuvant radioiodine therapy. Hormonal (L-thyroxine) treatment was administered to all patients. In 37 patients (8.6%) local recurrence was observed. 10-year overall survival was 96.4% and disease-free survival was respectively 68%. The comparison of Polish data to analysis in German population published by Holtzer et al. (Cancer, 2000) was also performed in this study. We conclude that DTC therapy, currently recommended in our country, gives satisfactory results and that clinical outcome and therapeutic methods are similar both in Poland and Germany.
authors.affiliation: Center of Oncology M. Sklodowska-Curie Memorial Institute, Gliwice, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Czarniecka
authors.forename: Jan
authors.initials: J
authors.lastname: Włoch
authors.forename: Michał
authors.initials: M
authors.lastname: Jarzab
authors.forename: Jolanta
authors.initials: J
authors.lastname: Krajewska
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Kukulska
authors.forename: Józef
authors.initials: J
authors.lastname: Roskosz
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Puch
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Wróbel
authors.forename: Magdalena
authors.initials: M
authors.lastname: Wollak
authors.forename: Maria
authors.initials: M
authors.lastname: Turska
authors.forename: Zoran
authors.initials: Z
authors.lastname: Stojcev
authors.forename: Bogusław
authors.initials: B
authors.lastname: Maka
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000473:pathology / Q000628:therapy; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002291:Carcinoma, Papillary / Q000473:pathology / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000706:statistics & numerical data; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D011044:Poland / Q000453:epidemiology; D018714:Radiotherapy, Adjuvant / Q000706:statistics & numerical data; D012044:Regression Analysis; D012189:Retrospective Studies; D016019:Survival Analysis; D013964:Thyroid Neoplasms / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D013965:Thyroidectomy / Q000706:statistics & numerical data
chemical_list: D000970:Antineoplastic Agents; D007457:Iodine Radioisotopes