Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion.
Hemoperfusion consists of the passage of anticoagulated blood through a column containing adsorbent particles. It was introduced in 1940 and refined from 1950 to 1970, and then introduced clinically for the treatment of acute intoxications between 1970 and 1980. Life-threatening valproic acid toxicity is an indication for coated charcoal hemoperfusion usually accomplished without complications, but we report a case of acute severe intravascular hemolysis during the time of hemoperfusion with coated charcoal column.
Rahman
Mohammed H
MH
Department of Medicine, Albany Medical College, Albany, New York 12208, USA.
Haqqie
Syed S
SS
McGoldrick
M Donald
MD
D058186:Acute Kidney Injury / Q000209:etiology*; D002606:Charcoal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006461:Hemolysis; D006464:Hemoperfusion / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D014635:Valproic Acid / Q000506:poisoning*
D002606:Charcoal; D014635:Valproic Acid