Identification of genes involved in healthy aging and longevity.
Studies suggest that the region around microsatellite marker D4S1564 on chromosome 4 is in some way linked to longevity. As a part of the integrated European project Genetics of Healthy Aging (GeHA), we set out to investigate the genes found in this region using a proteomics approach. Here, we report the cloning of six candidate genes.
Weibel
Jens
J
Department of Molecular Biology, University of Aarhus, Denmark.
Sørensen
Morten Draeby
MD
Kristensen
Peter
P
D000375:Aging / Q000235:genetics*; D002894:Chromosomes, Human, Pair 4; D003001:Cloning, Molecular; D020869:Gene Expression Profiling; D005796:Genes; D005819:Genetic Markers; D023281:Genomics / Q000379:methods; D006801:Humans; D008136:Longevity / Q000235:genetics*; D018895:Microsatellite Repeats; D021141:Nucleic Acid Amplification Techniques; D040901:Proteomics / Q000379:methods
D005819:Genetic Markers