title: Plasmablastic lymphoma presenting as an arm mass in an individual negative for human immunodeficiency virus: a case report.
abstract: Plasmablastic lymphoma is an aggressive diffuse large B-cell lymphoma classically arising in the oral cavities and jaws of individuals infected with the human immunodeficiency virus (HIV). More recently, cases of plasmablastic lymphoma have been identified in individuals negative for HIV. We report a case of plasmablastic lymphoma presenting as a rapidly expanding upper extremity mass in a 66-year-old individual negative for HIV. Aggressive multiple-agent chemotherapy resulted in a dramatic improvement of all symptoms. Increasing awareness of plasmablastic lymphoma in individuals who are HIV negative can allow for a better understanding of its clinical course and for specific chemotherapeutic regimens to be developed.
authors.affiliation: Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA. jeffkravetz@hotmail.com
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Kravetz
authors.forename: Michal G
authors.initials: MG
authors.lastname: Rose
authors.forename: Shakira
authors.initials: S
authors.lastname: Payne-Blackman
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Federman
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D018023:HIV Seronegativity; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000188:drug therapy* / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome