title: Melnick- needles osteodysplasty presenting with quadriparesis.
abstract: Melnick-Needles syndrome or osteodysplasty, a monogenic heritable bone dysplasia, is characterized by a typical facies and characteristic radiological findings. Less than 70 well-documented cases have been reported in literature; most of them were sporadic. We report the first case from Eastern India in an adolescent male, who had cranio-vertebral junction anomalies and presented with spastic quadriparesis at the age of 13 years.
authors.affiliation: Department of Medicine, Nil Ratan Sircar Medical College and Hospital, 138, A J C Bose Road, Kolkata 700 014.
authors.forename: S K
authors.initials: SK
authors.lastname: Bandyopadhyay
authors.forename: J
authors.initials: J
authors.lastname: Ghosal
authors.forename: Nandini
authors.initials: N
authors.lastname: Chakrabarti
authors.forename: Anita
authors.initials: A
authors.lastname: Dutta
mesh_terms: D000293:Adolescent; D002574:Cervical Vertebrae / Q000473:pathology*; D005799:Genes, Dominant; D008040:Genetic Linkage; D006801:Humans; D007194:India; D008297:Male; D010009:Osteochondrodysplasias / Q000235:genetics*; D010985:Platybasia / Q000473:pathology*; D011782:Quadriplegia / Q000235:genetics*