title: [Requirement of 25-hydroxyvitamin D in prevention of osteoporosis based on a pathophysiological perspective].
abstract: Vitamin D insufficiency is one of the risk factors of osteoporosis. Secondary hyperparathyroidism induced by low serum concentration of 25-hydroxyvitamin D (25-D), which is a most important nutritional marker to evaluate vitamin D status, results in bone loss and increase of fracture risk. In this topic, the recent findings related to the circulating concentration of 25-D for the prevention of osteoporosis are reviewed.
authors.affiliation: Kobe Pharmaceutical University, Department of Hygienic Sciences.
authors.forename: Naoko
authors.initials: N
authors.lastname: Tsugawa
mesh_terms: D015415:Biomarkers / Q000097:blood; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D018673:Nutrition Policy; D010024:Osteoporosis / Q000209:etiology* / Q000517:prevention & control*; D012307:Risk Factors; D014807:Vitamin D / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D014807:Vitamin D; C104450:25-hydroxyvitamin D