title: Giant cell reparative granuloma of the temporal bone treated with calcitonin.
abstract: OBJECTIVE
  A case report of a giant cell reparative granuloma involving the temporal bone successfully treated with calcitonin.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Teaching hospital, tertiary referral center.
  
  
  RESULTS
  A 62-year-old man was referred to the otolaryngology department with an extensive temporal bone lesion confirmed by biopsy to be a giant cell reparative granuloma. As an alternative to surgery, calcitonin therapy was commenced. After 12 months of treatment, clinical and audiological parameters had returned to normal, and radiological appearances had shown significant bony remodeling. These parameters remain stable 24 months after cessation of treatment.
  
  
  CONCLUSIONS
  Calcitonin is a safe and economical medical treatment, which should be considered for destructive giant cell granulomas of the temporal bone.
authors.affiliation: Department of Otolaryngology, Christchurch Hospital, Christchurch, New Zealand. drmelaniesouter@paradise.net.nz
authors.forename: Melanie A
authors.initials: MA
authors.lastname: Souter
authors.forename: Philip A
authors.initials: PA
authors.lastname: Bird
authors.forename: Jim P
authors.initials: JP
authors.lastname: Worthington
mesh_terms: D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001847:Bone Diseases / Q000188:drug therapy* / Q000473:pathology; D002116:Calcitonin / Q000008:administration & dosage / Q000627:therapeutic use*; D006101:Granuloma, Giant Cell / Q000188:drug therapy* / Q000473:pathology; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013701:Temporal Bone; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D002116:Calcitonin