Anthelmintic activity of Swertia chirata against gastrointestinal nematodes of sheep.
This paper describes in vitro and in vivo anthelmintic activities of Swertia chirata. In vitro studies revealed that at 25 mg/ml (P>/=0.05) the crude aqueous (CAE) and methanolic extracts (CME) of S. chirata whole plant showed an anthelmintic effect on live Haemonchus contortus. Moreover, in the in vivo study, the whole plant of S. chirata administered as crude powder (CP), CAE and CME at the dose of 3 g/kg to sheep naturally infected with mixed species of gastrointestinal nematodes, showed a significant reduction in egg per gram of faeces.
Iqbal
Zafar
Z
Chemotherapy Laboratory, Department of Veterinary Parasitology, University of Agriculture, Faisalabad, 38040, Pakistan. zafaruaf@yahoo.com
Lateef
Muhammad
M
Khan
Muhammad Nisar
MN
Jabbar
Abdul
A
Akhtar
Muhammad Shoaib
MS
D000284:Administration, Oral; D000818:Animals; D000969:Antinematodal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D005243:Feces / Q000469:parasitology; D005260:Female; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary; D008297:Male; D009348:Nematoda / Q000187:drug effects*; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D010270:Parasite Egg Count; D021261:Parasitic Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology; D029967:Swertia
D000969:Antinematodal Agents; D010936:Plant Extracts