title: Apoptotic and free radical scavenging properties of the methanolic extract of Gentianella alborosea.
abstract: Gentianella alborosea ("Hercampure") is a Peruvian species used in folk medicine for the treatment of a variety of health disorders. We tested the free radical scavenging (DPPH) and induction of apoptosis on a human uterus tumor cell line (HeLa) by its methanolic extract. The results showed a noticeable radical scavenging activity and a dose-dependent apoptotic effect.
authors.affiliation: Facultad de Farmacia, Universidad San Pablo CEU, Urbanización Montepríncipe, Boadilla del Monte 28660 Madrid, Spain. nacemes@ceu.es
authors.forename: Nuria
authors.initials: N
authors.lastname: Acero
authors.forename: Francisco
authors.initials: F
authors.lastname: Llinares
authors.forename: Antonio
authors.initials: A
authors.lastname: Galán de Mera
authors.forename: Beatriz
authors.initials: B
authors.lastname: Oltra
authors.forename: Dolores
authors.initials: D
authors.lastname: Muñoz-Mingarro
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D001713:Biphenyl Compounds; D004305:Dose-Response Relationship, Drug; D005260:Female; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D031313:Gentianella; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D008519:Medicine, Traditional; D010568:Peru; D008517:Phytotherapy; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl