title: Progressive resistance training during hemodialysis: rationale and method of a randomized-controlled trial.
abstract: Skeletal muscle wasting in patients receiving maintenance hemodialysis (HD) has been well documented. The rationale for prescribing progressive resistance training (PRT) in this cohort in an attempt to reverse this catabolism and induce a wide spectrum of physiological, functional, and psychological health-related adaptations is extremely strong. Unfortunately, the barriers to exercise adoption in this cohort are many, which may explain the persisting sedentariness of this population and the lack of widespread clinical programs such as are now commonplace in cardiac rehabilitation and pulmonary rehabilitation units. Current health care practices for HD patients do not address the negative health issues of inactivity and muscle wasting. Therefore, we conducted the first randomized-controlled trial to prescribe PRT during maintenance HD treatment. The purpose of this paper is to present the rationale and methodology that we utilized for implementing intradialytic PRT in a conventional outpatient HD clinic. Potential areas for modification of PRT regimens in this setting are also presented.
authors.affiliation: Institute of Food, Nutrition and Human Health, Te Kura Hangarua o Kai-oranga-a-tangata, Massey University, Wellington, New Zealand. B.Cheema@massey.ac.nz
authors.forename: Birinder S B
authors.initials: BS
authors.lastname: Cheema
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: O'Sullivan
authors.forename: Maria
authors.initials: M
authors.lastname: Chan
authors.forename: Aditi
authors.initials: A
authors.lastname: Patwardhan
authors.forename: John
authors.initials: J
authors.lastname: Kelly
authors.forename: Adrian
authors.initials: A
authors.lastname: Gillin
authors.forename: Maria A
authors.initials: MA
authors.lastname: Fiatarone Singh
mesh_terms: D005081:Exercise Therapy / Q000379:methods*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D006435:Renal Dialysis; D012107:Research Design