title: High prevalence of multidrug resistance and random distribution of mobile genetic elements among uropathogenic Escherichia coli (UPEC) of the four major phylogenetic groups.
abstract: One hundred and ten UTI Escherichia coli strains, from Ljubljana, Slovenia, were analyzed for antibiotic resistances, mobile DNA elements, serotype, and phylogenetic origin. A high prevalence of drug resistance and multidrug resistance was found. Twenty-six percent of the isolates harbored a class 1 integron, while a majority of the strains (56%) harbored rep sequences characteristic of F-like plasmids. int as well as rep sequences were found to be distributed in a random manner among strains of the four major phylogenetic groups indicating that all groups have a similar tendency to acquire and maintain mobile genetic elements frequently associated with resistance determinants.
authors.affiliation: Department of Biology, Biotechnical Faculty, University of Ljubljana, 1000, Ljubljana, Slovenia.
authors.forename: Matija
authors.initials: M
authors.lastname: Rijavec
authors.forename: Marjanca
authors.initials: M
authors.lastname: Starcic Erjavec
authors.forename: Jerneja
authors.initials: J
authors.lastname: Ambrozic Avgustin
authors.forename: Rolf
authors.initials: R
authors.lastname: Reissbrodt
authors.forename: Angelika
authors.initials: A
authors.lastname: Fruth
authors.forename: Veronika
authors.initials: V
authors.lastname: Krizan-Hergouth
authors.forename: Darja
authors.initials: D
authors.lastname: Zgur-Bertok
mesh_terms: D003227:Conjugation, Genetic; D018432:Drug Resistance, Multiple / Q000235:genetics*; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000382:microbiology; D032023:Integrons; D020071:Interspersed Repetitive Sequences; D010802:Phylogeny; D010957:Plasmids; D012093:Replicon; D012703:Serotyping; D017524:Slovenia; D014552:Urinary Tract Infections / Q000382:microbiology