Rustling synaptic vesicle cargo after exocytosis.
In this issue of Neuron, Voglmaier et al. provide new evidence that the retrieval of synaptic vesicle transporters after exocytosis proceeds along at least two different endocytic pathways. This work provides new insight into the mechanisms of sorting synaptic vesicle cargo at the cell surface.
Grabner
Chad
C
Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520, USA.
Zenisek
David
D
D000217:Acyltransferases / Q000378:metabolism; D033963:Adaptor Protein Complex 3 / Q000378:metabolism; D000818:Animals; D005089:Exocytosis / Q000502:physiology*; D018698:Glutamic Acid / Q000378:metabolism*; D006801:Humans; D017729:Presynaptic Terminals / Q000378:metabolism*; D020033:Protein Isoforms / Q000378:metabolism; D021381:Protein Transport / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology; D013572:Synaptic Vesicles / Q000378:metabolism*; D050496:Vesicular Glutamate Transport Proteins / Q000378:metabolism*
D033963:Adaptor Protein Complex 3; D020033:Protein Isoforms; D050496:Vesicular Glutamate Transport Proteins; D018698:Glutamic Acid; D000217:Acyltransferases; C018764:2-acylglycerophosphate acyltransferase