title: The Thr354Ile substitution in PSEN1:: disease-causing mutation or polymorphism?
authors.affiliation: Department of Neurology, University of California Los Angeles, 90095-1769, USA.
authors.forename: Peiyee
authors.initials: P
authors.lastname: Lee
authors.forename: Luis
authors.initials: L
authors.lastname: Medina
authors.forename: John M
authors.initials: JM
authors.lastname: Ringman
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D008875:Middle Aged; D009154:Mutation; D011110:Polymorphism, Genetic; D053764:Presenilin-1; D013912:Threonine / Q000235:genetics*
chemical_list: D008565:Membrane Proteins; C508853:PSEN1 protein, human; D053764:Presenilin-1; D013912:Threonine