Effects of oestrogen and progestogen on serum levels of alpha(2)-macroglobulin, transferrin, albumin, and IgG.
The levels of four serum proteins, assayed by a radial immunodiffusion technique, have been measured in healthy women who had been given either the oestrogen or progestogen component of a combined oral contraceptive preparation for three weeks. Raised alpha(2)-macroglobulin and transferrin levels were found after oestrogen treatment but albumin and IgG did not significantly alter. In the progestogen-treated group all four proteins remained unchanged. The four proteins have also been assayed at frequent intervals during the normal menstrual cycle. No evidence of cyclical variation was found.
Horne
C H
CH
University Department of Pathology, Western Infirmary, Glasgow.
Mallinson
A C
AC
Ferguson
J
J
Goudie
R B
RB