title: [A case of Prader-Willi syndrome treated by vitrectomy].
abstract: BACKGROUND
  We report a successful treatment by vitrectomy in an adult case of Prader-Willi syndrome.
  
  
  METHODS
  We encountered a case of Prader-Willi syndrome in a 29-year-old male patient with proliferative diabetic retinopathy and cataract. We performed a vitrectomy and a cataract extraction on the patient. Initial examination showed proliferative diabetic retinopathy in both eyes. Funduscopy revealed tractional retinal detachment with atrophic retina in the right eye and retinal detachment in the inferior half of the fundus with vitreous hemorrhage in the left eye. We performed a vitrectomy with a combination of phacoemulsification and intraocular lens implantation only on the left eye. Visual acuity in the left eye increased from counting fingers preoperatively to 0.6(n.c) postoperatively. The right eye was left untreated because the visual prognosis was not expected to improve even if the eye received surgical intervention. The final visual acuity in the right eye was no light perception at the end of the follow-up period.
  
  
  CONCLUSIONS
  Careful follow-up and early treatment are necessary for patients with diabetic retinopathy accompanied by Prader-Willi syndrome as it could develop into blindness.
authors.affiliation: Department of Ophthalmology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Kaori
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Sadao
authors.initials: S
authors.lastname: Hori
mesh_terms: D000328:Adult; D002387:Cataract Extraction; D003930:Diabetic Retinopathy / Q000601:surgery*; D006801:Humans; D008297:Male; D011218:Prader-Willi Syndrome / Q000150:complications*; D014821:Vitrectomy