title: Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.
abstract: OBJECTIVE
  To evaluate the surgical treatment, we investigated that performed for chronic pancreatitis patients suffering from severe pain resistant to conservative treatments.
  
  
  METHODS
  Nineteen chronic pancreatitis patients with severe pain resistant for a long time to previous conservative medical and/or interventional treatments underwent surgery retrospectively. We evaluated a difference of postoperative improvement of symptoms in patients with surgical treatment including nerve plexus resection.
  
  
  RESULTS
  The mean follow-up interval after surgery was 59.7 months (range, 3.0-187.3 months). Of 19 patients, 14 (73.7%) underwent nerve plexus resection. Relief of symptoms was observed in 16 of 19 patients (84.2%). Fourteen of the 15 patients (93.3%) in the nerve plexus resection group were relieved of symptoms after surgery, compared to only two of four (50.0%) patients in the nerve plexus non-resection group.
  
  
  CONCLUSIONS
  Surgical treatments with nerve plexus resection appropriately matched with individual patients are very safe and contribute to the improvement of the quality of life for chronic pancreatitis patients resistant to conservative treatments.
authors.affiliation: Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku Nagoya 4678601, Japan. cb8h-swi@asahi-net.or.jp
authors.forename: Hirozumi
authors.initials: H
authors.lastname: Sawai
authors.forename: Yuji
authors.initials: Y
authors.lastname: Okada
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Funahashi
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Matsuo
authors.forename: Minoru
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Moritsugu
authors.initials: M
authors.lastname: Tanaka
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takeyama
authors.forename: Tadao
authors.initials: T
authors.lastname: Manabe
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D019299:Decompression, Surgical; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010148:Intractable Pain / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D010179:Pancreas / Q000000981:diagnostic imaging* / Q000294:innervation* / Q000601:surgery; D010180:Pancreatectomy; D010183:Pancreatic Ducts / Q000601:surgery; D016577:Pancreaticoduodenectomy; D010193:Pancreaticojejunostomy; D050500:Pancreatitis, Chronic / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D010525:Peripheral Nerves / Q000601:surgery*; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000700:Analgesics