A new locus for synaptic plasticity in cerebellar circuits.
Experimental and computational analyses of cerebellar function indicate that excitatory synapses onto deep nucleus neurons are likely to be a critical site of plasticity during motor learning. In this issue of Neuron, Pugh and Raman report that unconventional stimulus protocols can drive synaptic plasticity in the deep cerebellar nuclei.
Bagnall
Martha W
MW
Salk Institute, UCSD Neurosciences Graduate Program, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
du Lac
Sascha
S
D000818:Animals; D002529:Cerebellar Nuclei / Q000502:physiology*; D003213:Conditioning, Psychological / Q000502:physiology; D006801:Humans; D007858:Learning / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology