[A case of sarcomatoid hepatocellular carcinoma in a young female without risk factor].
A previously healthy 22-year-old woman was admitted with a complaint of right upper quadrant abdominal pain for 2 weeks. Her past history was not remarkable. On admission, HBsAg and anti-HCV were negative and alpha-FP was within normal range. Abdominal sonography and CT showed a mass in liver measuring 10 x 11 cm with features of central necrosis and hemorrhage. On 6th hospital day, hemoperitoneum developed suddenly. She underwent emergency laparotomy and trisegmentectomy. Intraoperative finding revealed a hemoperitoneum with a tumor filled with liquefied necrotic tissues. Microscopically, the tumor was mostly composed of pleomorphic spindle cells with abundant anastomosing vascular channels and partly composed of tumor cells with trabecular arrangement. On immunohistochemical staining, tumor cells reacted with cytokeratin and vimentin, while CD34 and hepatocyte staining revealed negative. She died 2 months after the operation. We report a case of rapidly deteriorated primary sarcomatoid hepatocellular carcinoma in a young female without any risk factor.
Nam
Hyo Sung
HS
Department of Internal Medincine, KwangMyungSungAe Hospital, Gwangmyeong, Korea.
Kim
Hae Kyung
HK
Ma
Sae Ung
SU
Yu
Byung Hyun
BH
Jung
Ki Myung
KM
Gong
Kyung Taek
KT
Lee
Yong Ju
YJ
Park
Tae Il
TI
Hu
Byung Won
BW
Park
Shin Hee
SH
Na
Jin Yung
JY
Choi
Jin Uk
JU
Kim
Ho Jung
HJ
Yu
Uen Sil
US
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology*