Gene expression microarrays: glimpses of the immunological genome.
Successful microarray experimentation can generate enormous amounts of data, potentially very rich but also very unwieldy. Bold outlooks and new methods for data analysis and presentation should yield additional insight into the complexities of the immune system.
Hyatt
Gordon
G
Section on Immunology and Immunogenetics, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA.
Melamed
Rachel
R
Park
Richard
R
Seguritan
Reuben
R
Laplace
Catherine
C
Poirot
Laurent
L
Zucchelli
Silvia
S
Obst
Reinhard
R
Matos
Michael
M
Venanzi
Emily
E
Goldrath
Ananda
A
Nguyen
Linh
L
Luckey
John
J
Yamagata
Tetsuya
T
Herman
Ann
A
Jacobs
Jonathan
J
Mathis
Diane
D
Benoist
Christophe
C
D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism; D003626:Data Display; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000235:genetics; D023281:Genomics / Q000379:methods*; D006801:Humans; D007109:Immunity / Q000235:genetics*; D016131:Lymphocyte Subsets / Q000378:metabolism; D015201:Meta-Analysis as Topic; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis; D012323:RNA Processing, Post-Transcriptional; D012326:RNA Splicing; D013601:T-Lymphocytes / Q000378:metabolism; D009626:Terminology as Topic; D014158:Transcription, Genetic