title: Left ventricular diastolic dysfunction in obese women.
abstract: OBJECTIVE
  To determine the direct effect of obesity on echocardiographic indices of diastolic left ventricular function
  
  
  METHODS
  44 obese (BMI > or =25 kg/m2) and 45 normal weight women were studied. They had no other pathological conditions. Echocardiographic indices of diastolic function were obtained, and dysfunction was assumed when at least two values differed by > or =2 SD from the normal weight group.
  
  
  RESULTS
  In obese subjects, the values of maximum velocity of active mitral filling (A) were increased and pulmonary diastolic velocity was decreased significantly (p< 0,01); all other diastolic variables were unchanged. Subclinical diastolic dysfunction tend to be more prevalent among obese subjects but it was not significantly different from non obese (p= 0.11), being present in nine obese (20.5%) and 4 normal (8.9%) subjects.
  
  
  CONCLUSIONS
  Subclinical left ventricular diastolic dysfunction is present in obese women.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta.
authors.forename: Idrus
authors.initials: I
authors.lastname: Alwi
authors.forename: S
authors.initials: S
authors.lastname: Harun
authors.forename: Satrio
authors.initials: S
authors.lastname: Sukmono
authors.forename: Pradana
authors.initials: P
authors.lastname: Suwondo
authors.forename: Maryantoro
authors.initials: M
authors.lastname: Oemardi
authors.forename: Sarwono
authors.initials: S
authors.lastname: Waspadji
authors.forename: Sidartawan
authors.initials: S
authors.lastname: Soegondo
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003971:Diastole / Q000502:physiology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D009765:Obesity / Q000503:physiopathology*; D018617:Ultrasonography, Doppler, Pulsed; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*