title: Common region CR1 for expression of antibiotic resistance genes.
abstract: The CR1 element defined by an orf513 gene encoding a putative recombinase and a recombination crossover site has been identified upstream of several antibiotic resistance genes in Enterobacteriaceae. This CR1 element was shown to bring promoter sequences that play a role in the expression of unrelated antibiotic resistance genes.
authors.affiliation: Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris Sud, K-Bicêtre, France.
authors.forename: Jose-Manuel
authors.initials: JM
authors.lastname: Rodriguez-Martinez
authors.forename: Laurent
authors.initials: L
authors.lastname: Poirel
authors.forename: Rafael
authors.initials: R
authors.lastname: Canton
authors.forename: Patrice
authors.initials: P
authors.lastname: Nordmann
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004755:Enterobacteriaceae / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D045522:Recombinases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D045522:Recombinases