Determination of urinary trace elements (arsenic, copper, cadmium, manganese, lead, zinc, selenium) in patients with Blackfoot disease.
To determine the relationship of arsenic, copper, cadmium, manganese, lead, zinc and selenium to Blackfoot disease (BFD, a peripheral vascular disorder endemic to areas of Taiwan, which has been linked to arsenic in drinking water) the authors measured the amount of these substances in urine from BFD patients, using atomic absorption spectrometry. Results indicate significantly higher amounts of urinary arsenic, copper, cadmium, manganese, and lead for BFD patients than for normal controls, also significantly lower urinary zinc and selenium.
Tsai
Jin-Lian
JL
Graduate Institute of Occupational Safety, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Horng
Pin-Hua
PH
Hwang
Tzung-Jeng
TJ
Hsu
John W
JW
Horng
Ching-Jyi
CJ
D001151:Arsenic / Q000652:urine*; D020261:Arsenic Poisoning / Q000453:epidemiology* / Q000209:etiology; D002104:Cadmium / Q000652:urine*; D016022:Case-Control Studies; D003300:Copper / Q000652:urine*; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D006801:Humans; D007854:Lead / Q000652:urine; D008297:Male; D008345:Manganese / Q000652:urine; D016491:Peripheral Vascular Diseases / Q000453:epidemiology* / Q000209:etiology; D012643:Selenium / Q000652:urine*; D013054:Spectrophotometry, Atomic; D013624:Taiwan / Q000453:epidemiology; D014874:Water Pollutants, Chemical / Q000009:adverse effects* / Q000652:urine; D015032:Zinc / Q000652:urine
D014874:Water Pollutants, Chemical; D002104:Cadmium; D007854:Lead; D008345:Manganese; D003300:Copper; D012643:Selenium; D015032:Zinc; D001151:Arsenic