title: Emergence of carbapenem resistance in Acinetobacter baumannii recovered from blood cultures in Australia.
abstract: We describe the first emergence of carbapenem-resistant Acinetobacter baumannii in Australia. Ninety A. baumannii isolates recovered from cultures of blood specimens from 69 patients were analyzed. Overall, 58 isolates (64%) were resistant to meropenem. The chi 2 test for linear trend revealed that emergence of carbapenem resistance was statistically significant during the 32-month study period. Selected isolates were of the same clonal type, and no genes encoding carbapenemases were identified.
authors.affiliation: Infectious Diseases Unit, Alfred Hospital, Melbourne, Victoria, Australia. antonpeleg@iprimus.com.au
authors.forename: Anton Y
authors.initials: AY
authors.lastname: Peleg
authors.forename: Clare
authors.initials: C
authors.lastname: Franklin
authors.forename: Jan M
authors.initials: JM
authors.lastname: Bell
authors.forename: Denis W
authors.initials: DW
authors.lastname: Spelman
mesh_terms: D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016470:Bacteremia / Q000382:microbiology*; D015780:Carbapenems / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006801:Humans; D014739:Victoria
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems