title: [Long-term follow-up results of synovectomy for rheumatoid knee].
abstract: OBJECTIVE
  To continuously observe the long-term effects of synovectomy for improving joint damage and quality-of-life in patients with the rheumatoid knee.
  
  
  METHODS
  Twenty-one consecutive patients with rheumatoid arthritis (RA) involving 24 knees underwent open synovectomy from November 1988 to January 1997 between November 1988 and January 1997. The changes in radiographic damage were assessed with Larsen score on plain films before and 6 months after surgery with subsequent annual assessment for 8 years, and the functional recovery of the patients was also evaluated with Health Assessment Questionnaire (HAQ) at the same time.
  
  
  RESULTS
  The radiographic joint damage and juxta-articular osteoporosis or bone erosion was ameliorated after surgery in all the patients. Larsen score began to decrease 6 months after the operation, and the best effects were achieved at one year and maintained for at least 5 years after the operation, but then followed by recurrence of joint lesions. HAQ scores were improved after the surgery with the best effects observed 6 months after the operation lasting for over 2 years. HAQ score gradually decreased 4 years after the operation till reaching the preoperative scores.
  
  
  CONCLUSIONS
  Synovectomy in the patients with rheumatoid knee not only reverses progressive joint damage, but also improves juxta-articular bone erosions and the patients' quality of life. However, radiographic joint damage and functional deterioration may recur due to hyperplasia of the inflammatory synovium in the long term after operation, suggesting that the inflammatory synovium participates in local joint damage with bone erosions and systemic pathologic process of RA.
authors.affiliation: Department of Orthopedics, First Clinical College of Shantou University, Shantou 515041, China.
authors.forename: Run-ming
authors.initials: RM
authors.lastname: Zeng
authors.forename: Yu-cai
authors.initials: YC
authors.lastname: Zou
authors.forename: Jing
authors.initials: J
authors.lastname: Lin
authors.forename: Zi-jian
authors.initials: ZJ
authors.lastname: Zhao
authors.forename: Meng-zhang
authors.initials: MZ
authors.lastname: Liu
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Li
mesh_terms: D000328:Adult; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D000074402:Synovectomy; D013997:Time Factors