[Femoral artery pseudoaneurysms: treatment with ultrasound guided thrombin injection in 28 patients].
BACKGROUND
Femoral artery pseudoaneurysms (PSA) develop in 0.2-8% patients undergoing procedures that require femoral artery cannulation. Ultrasound guided thrombin injection has been described as successful and safe alternative to ultrasound guided compression and surgical treatment.


OBJECTIVE
Assessment of efficacy and safety of PSA treatment with USGTI.


METHODS
28 patients (pts) (18 female, mean age 64.6 +/- 11.4) with femoral pseudoaneurysms developed due to coronary angiogram or percutaneous coronary angioplasty were treated with ultrasound guided thrombin injection. 24 PSAs arose from right common femoral artery, 3 from right superficial femoral artery, and 1 from left common femoral artery. 24 patients were receiving antiplatelet and 4 anticoagulation therapy at the time of the procedure. With ultrasound guidance, a 21Gx11/2 needle was placed into pseudoaneurysm lumen followed by thrombin injection (1074 +/- 473 U). No complications of the procedure were observed. In 24-hour observation USGTI was successful in 28 (100%) patients. However, in 7-day follow-up resolution of 1 PSA was found, which reduced efficacy rate to 96.3%.


CONCLUSIONS
Ultrasound guided thrombin injection is a successful, safe and well tolerated method of pseudoaneurysms treatment. Neither antiplatelet nor anticoagulation therapy affects success rate of the method.
Duszańska
Agata
A
I Katedra i Oddział Kliniczny Kardiologii Slaskiej Akademii Medycznej, Slaskie Centrum Chorób Serca w Zabrzu. agataduszanska@op.pl
Dzióbek
Bogusława
B
Swierad
Marcin
M
Piegza
Jacek
J
Kukulski
Tomasz
T
Poloński
Lech
L
Kalarus
Zbigniew
Z
D000368:Aged; D017541:Aneurysm, False / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000209:etiology; D006328:Cardiac Catheterization / Q000009:adverse effects; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000187:drug effects; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D007269:Injections, Intra-Arterial / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
D006490:Hemostatics; D013917:Thrombin