title: [Femoral artery pseudoaneurysms: treatment with ultrasound guided thrombin injection in 28 patients].
abstract: BACKGROUND
  Femoral artery pseudoaneurysms (PSA) develop in 0.2-8% patients undergoing procedures that require femoral artery cannulation. Ultrasound guided thrombin injection has been described as successful and safe alternative to ultrasound guided compression and surgical treatment.
  
  
  OBJECTIVE
  Assessment of efficacy and safety of PSA treatment with USGTI.
  
  
  METHODS
  28 patients (pts) (18 female, mean age 64.6 +/- 11.4) with femoral pseudoaneurysms developed due to coronary angiogram or percutaneous coronary angioplasty were treated with ultrasound guided thrombin injection. 24 PSAs arose from right common femoral artery, 3 from right superficial femoral artery, and 1 from left common femoral artery. 24 patients were receiving antiplatelet and 4 anticoagulation therapy at the time of the procedure. With ultrasound guidance, a 21Gx11/2 needle was placed into pseudoaneurysm lumen followed by thrombin injection (1074 +/- 473 U). No complications of the procedure were observed. In 24-hour observation USGTI was successful in 28 (100%) patients. However, in 7-day follow-up resolution of 1 PSA was found, which reduced efficacy rate to 96.3%.
  
  
  CONCLUSIONS
  Ultrasound guided thrombin injection is a successful, safe and well tolerated method of pseudoaneurysms treatment. Neither antiplatelet nor anticoagulation therapy affects success rate of the method.
authors.affiliation: I Katedra i Oddział Kliniczny Kardiologii Slaskiej Akademii Medycznej, Slaskie Centrum Chorób Serca w Zabrzu. agataduszanska@op.pl
authors.forename: Agata
authors.initials: A
authors.lastname: Duszańska
authors.forename: Bogusława
authors.initials: B
authors.lastname: Dzióbek
authors.forename: Marcin
authors.initials: M
authors.lastname: Swierad
authors.forename: Jacek
authors.initials: J
authors.lastname: Piegza
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kukulski
authors.forename: Lech
authors.initials: L
authors.lastname: Poloński
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Kalarus
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000209:etiology; D006328:Cardiac Catheterization / Q000009:adverse effects; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000187:drug effects; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D007269:Injections, Intra-Arterial / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
chemical_list: D006490:Hemostatics; D013917:Thrombin