[Anti-infective drug therapy in ophthalmology--part 4: acanthamoeba keratitis].
An early diagnosis of an acanthamoeba keratitis can usually be made on the basis of the patient's history and slit-lamp examination. Further helpful diagnostic steps are confocal microscopy, microbiological, and histopathological examination. In the early stages topical application of antimicrobials (combined application of aminoglycosides, polyhexamethylene biguanide 0.02 %, propamidine isoethionate 0.1 %) is effective. In the late stages a penetrating keratoplasty is often necessary.
Reinhard
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Augenklinik des Universitätsklinikums, Killianstr. 5, 79106 Freiburg. Reinhard@aug.ukl.uni-freiburg.de
Behrens-Baumann
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D015823:Acanthamoeba Keratitis / Q000175:diagnosis* / Q000628:therapy*; D000977:Antiparasitic Agents / Q000008:administration & dosage*; D016039:Corneal Transplantation / Q000379:methods*; D006801:Humans; D009885:Ophthalmology / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'
D000977:Antiparasitic Agents