Application of beta-lactamase-dependent prodrugs in clostridial-directed enzyme therapy (CDEPT): a proposal.
Tirandaz
Hassan
H
Hamedi
Javad
J
Marashi
Sayed-Amir
SA
D003013:Clostridium; D043525:Cytosine Deaminase / Q000627:therapeutic use; D016503:Drug Delivery Systems; D015316:Genetic Therapy / Q000379:methods*; D008954:Models, Biological; D009369:Neoplasms / Q000235:genetics / Q000628:therapy; D009601:Nitroreductases / Q000627:therapeutic use; D010957:Plasmids; D011355:Prodrugs / Q000008:administration & dosage* / Q000378:metabolism; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D011355:Prodrugs; D009601:Nitroreductases; D001618:beta-Lactamases; D043525:Cytosine Deaminase