title: Quetiapine vs. risperidone in treating psychosis in neurosyphilis: a case report.
abstract: OBJECTIVE
  A 44-year-old male patient presented with agitation, auditory hallucinations, and delusions of persecution was diagnosed as having neurosyphilis.
  
  
  METHODS
  He was treated with penicillin G 24 million units/day, risperidone 6 mg/day, and memantine 20 mg/day with partial response to psychotic symptoms and significant extrapyramidal symptoms.
  
  
  RESULTS
  On his follow-up, after 5 months, his cognitive status and serological tests remained the same, and his cell count was increased. A second therapy of penicillin was administered without any clinical improvement. On his second hospitalization for severe psychotic agitation after approximately 1 year, quetiapine 1200 mg/day was introduced and the psychiatric state improved immediately without significant side effect.
  
  
  CONCLUSIONS
  Quetiapine, which has a low potential for producing extrapyramidal side effects, should be considered in the treatment of psychotic symptoms of neurosyphilis.
authors.affiliation: Department of Psychiatry, Cerrahpasa Medical Faculty, Istanbul University, 34098 Istanbul, Turkey. okantaycan@yahoo.com
authors.forename: Okan
authors.initials: O
authors.lastname: Taycan
authors.forename: Mufit
authors.initials: M
authors.lastname: Ugur
authors.forename: Mine
authors.initials: M
authors.lastname: Ozmen
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D003987:Dibenzothiazepines / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009494:Neurosyphilis / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D010406:Penicillins / Q000627:therapeutic use; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000209:etiology*; D000069348:Quetiapine Fumarate; D018967:Risperidone / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D010406:Penicillins; D000069348:Quetiapine Fumarate; D018967:Risperidone