Breast-feeding in a woman with cystic fibrosis undergoing antibiotic intravenous treatment.
We report the case of a 30-year-old woman with cystic fibrosis (CF) chronically infected with Pseudomonas aeruginosa who delivered and breast-fed a healthy boy. While breast-feeding the woman had to undergo an i.v. antibiotic course with tobramycin, due to pulmonary exacerbation. Tobramycin was not detected in her milk and lactation could be continued. This is the first time that the presence of tobramycin in the milk of a CF woman during i.v. administration has been investigated.
Festini
Filippo
F
Division of Nursing Sciences, Department of Pediatrics, University of Florence, Florence, Italy. filippo.festini@unifi.it
Ciuti
Riccardo
R
Taccetti
Giovanni
G
Repetto
Teresa
T
Campana
Silvia
S
De Martino
Maurizio
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use; D003550:Cystic Fibrosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D008895:Milk, Human / Q000378:metabolism*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011296:Prenatal Diagnosis; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014031:Tobramycin / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014031:Tobramycin