title: Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study.
abstract: OBJECTIVE
  To measure the risk of colorectal cancer and adenoma with new onset rectal bleeding reported to primary care.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  A rural general practice in the United Kingdom.
  
  
  METHODS
  Patients aged 45 or more with new onset rectal bleeding, irrespective of other symptoms.
  
  
  METHODS
  Percentage of participants in whom colorectal cancer or colonic adenoma was identified after investigation of the bowel.
  
  
  RESULTS
  During a 10 year period, 265 patients reported new rectal bleeding. Of these, 15 (5.7%, 95% confidence interval 3.2% to 9.2%) had colorectal cancer, and 13 (4.9%, 2.6% to 8.4%) had colonic adenoma. Only two of the patients with cancer had had diarrhoea.
  
  
  CONCLUSIONS
  One in 10 patients aged 45 or more with new onset rectal bleeding had colonic neoplasia, so investigation of the bowel should be offered to all such patients, whether or not they have other symptoms.
authors.affiliation: Hoyland House, Painswick, Gloucestershire GL6 6RD.
authors.forename: Jennifer
authors.initials: J
authors.lastname: du Toit
authors.forename: William
authors.initials: W
authors.lastname: Hamilton
authors.forename: Kevin
authors.initials: K
authors.lastname: Barraclough
mesh_terms: D000236:Adenoma / Q000209:etiology*; D000368:Aged; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000209:etiology*; D005194:Family Practice; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D012002:Rectal Diseases / Q000209:etiology*; D012307:Risk Factors; D012423:Rural Health