title: [Newly diagnosed abnormal glucose tolerance in patients with acute coronary syndrome and without known diabetes mellitus].
abstract: OBJECTIVE
  To investigate the prevalence of newly diagnosed abnormal glucose tolerance in patients with acute coronary syndrome and without known diabetes mellitus (DM) and to access the correlation of glycometabolic abnormality with traditional risk factors of cardiovascular diseases.
  
  
  METHODS
  The clinical data of 1328 patients with cute coronary syndrome (ACS), without previous DM, and with the admission blood glucose < 11.1 mmol/ who were consecutively admitted in 52 hospitals of 7 cities in China from June 1 to August 31 2005, were collected. A simple oral glucose tolerance test (OGTT) was conducted before they were discharged.
  
  
  RESULTS
  Glycometabolic perturbation was seen in 887 of the 1328 patients (67%). The prevalence rates of newly diagnosed DM and impaired glucose regulation (IGR) were 22% and 45% respectively. Blood pressure, blood lipid, body mass index, waistline, and hemoglobin A1C were all significantly higher in those with glycometabolic perturbation than in those with normal glucose metabolism (all P < 0.05). Waistline and blood lipid were the risk factors of abnormal glycometabolic status (both P < 0.05).
  
  
  CONCLUSIONS
  Newly diagnosed DM is common among the ACS patients without DM history. Newly diagnosed glycometabolic status is associated with waistline and blood lipid.
authors.affiliation: Department of Cardiology, People's Hospital, Peking University, Beijing 100044, China.
authors.forename: Ming-zhu
authors.initials: MZ
authors.lastname: Yan
authors.forename: Da-yi
authors.initials: DY
authors.lastname: Hu
authors.forename: Jin-ming
authors.initials: JM
authors.lastname: Yu
authors.forename: Yi-hong
authors.initials: YH
authors.lastname: Sun
authors.forename: Wen-ling
authors.initials: WL
authors.lastname: Liu
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000503:physiopathology; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D018149:Glucose Intolerance / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence
chemical_list: D001786:Blood Glucose