[Mature cystic teratoma of the ovary with a small ganglioneuroma].
A case of ganglioneuroma arising within a cystic mature teratoma of the ovary in a 34-year-old woman is reported. Patient underwent right adnexectomy. The ovary was completely replaced by a bilocular cystic lesion, measuring 8 cm in diameter and filled with adipose tissue and pilosebaceous material. Microscopically the cyst was composed by a mature cystic teratoma containing skin with dermal appendages, fatty tissue and bronchial epithelium. Furthermore a nodule (0.5 cm in size) composed of mature ganglion cells, axons and Schwann cells, was identified. Ganglion cells were positive for NSE and synaptophysin, while Schwann cells stained positively with S100 protein and GFAP. To the best of our knowledgment this is the first reported cases of ganglioneuroma arisen within a cystic mature teratoma of the ovary.
Marucci
G
G
Dipartimento di Scienze Oncologiche, Sezione di Anatomia Istologia e Citologia Patologica Marcello Malpighi, Ospedale Bellaria, Università di Bologna, Bologna, Italia.
Collina
G
G
D000328:Adult; D001369:Axons / Q000737:chemistry / Q000473:pathology; D005260:Female; D005729:Ganglioneuroma / Q000737:chemistry / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000473:pathology*; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D012583:Schwann Cells / Q000737:chemistry / Q000473:pathology; D016708:Synaptophysin / Q000032:analysis; D013724:Teratoma / Q000737:chemistry / Q000473:pathology*
D005904:Glial Fibrillary Acidic Protein; D019394:Ki-67 Antigen; D009363:Neoplasm Proteins; D009418:S100 Proteins; D016708:Synaptophysin; D010751:Phosphopyruvate Hydratase