Freezing of random RNA.
We study secondary structures of random RNA molecules by means of a renormalized field theory based on an expansion in the sequence disorder. We show that there is a continuous phase transition from a molten phase at higher temperatures to a low-temperature glass phase. The primary freezing occurs above the critical temperature, with local islands of stable folds forming within the molten phase. The size of these islands defines the correlation length of the transition. Our results include critical exponents at the transition and in the glass phase.
Lässig
Michael
M
Institut für theoretische Physik, Universität zu Köln, Zülpicher Strasse 77, 50937 Köln, Germany.
Wiese
Kay Jörg
KJ
D005615:Freezing; D008954:Models, Biological; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*
D012313:RNA