Ureteral obstruction after dextranomer/hyaluronic acid copolymer injection for treatment of secondary vesicoureteral reflux after renal transplantation.
Ureteral obstruction after transurethral injection therapy for primary vesicoureteral reflux is known to occur in less than 1% of cases. We report the first case of a ureteral obstruction after transurethral injection of dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of secondary vesicoureteral reflux after renal transplantation. Loss of transplant function made reimplantation of the ureter necessary. A periureteral phlebitis and moderate foreign body reaction was found histologically, although the patient had received immunosuppressive therapy. Endoscopic therapy of secondary vesicoureteral reflux in patients after renal transplantation is a reasonable minimally invasive treatment option; however, severe complications may occur.
Seifert
Hans-Helge
HH
Department of Urology, University Hospital Basel, Basel, Switzerland. seiferth@uni-duesseldorf.de
Mazzola
Brunello
B
Zellweger
Tobias
T
Ruszat
Robin
R
Muller
Alexander
A
Burkhalter
Felix
F
Steiger
Jörg
J
Sulser
Tullio
T
Bachmann
Alexander
A
D003911:Dextrans / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005549:Foreign-Body Reaction / Q000150:complications* / Q000209:etiology; D006801:Humans; D007267:Injections; D016030:Kidney Transplantation; D008875:Middle Aged; D011183:Postoperative Complications; D019736:Prostheses and Implants / Q000009:adverse effects*; D014517:Ureteral Obstruction / Q000209:etiology*; D014718:Vesico-Ureteral Reflux / Q000628:therapy*
D003911:Dextrans; C013471:dextranomer