[Kikuchi-Fujimoto disease: review of four cases].
Kikuchi-Fujimoto disease is an uncommon form of lymphadenitis, firstly described in Japan. Etiology is unknown. It affects mainly young women. It commonly manifests as a painful cervical lymphadenitis usually associated with fever and leukopenia. Clinical course users to be benign, leading spontaneously to a complete recovery. Histological findings include necrotizing changes with cariorrhesis, partial loss of ganglionar architecture and foci of histiocytic infiltrates in the cortical and/or paracortical zones of the lymph nodes. A common finding is the absence of neutrophil granulocytes in the inflammatory infiltrates, in contrast to other necrotizing lymphadenitis. We report four cases of Kikuchi-Fujimoto disease, recently identified in our hospital.
Montejo
M
M
Unidad de Enfermedades Infecciosas, Servicios de Pediatría, Hospital de Cruces, Universidad del País Vasco, 48009 Bilbao. secretaria.infecciosos@hcru.osakidetza.net
Lekerika
N
N
Astigarraga
I
I
Aguirrebengoa
K
K
Goikoetxea
J
J
Erdozain
J G
JG
Bidaurrazaga
N
N
D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis*; D006801:Humans; D008297:Male