Does excitotoxic cell death of motor neurons in ALS arise from glutamate transporter and glutamate receptor abnormalities?
Rattray
Marcus
M
King's College London, Wolfson Centre for Age-Related Diseases, Guy's Hospital Campus, London SE1 1UL, UK.
Bendotti
Caterina
C
D000690:Amyotrophic Lateral Sclerosis / Q000378:metabolism / Q000503:physiopathology*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D016923:Cell Death / Q000502:physiology; D003998:Dicarboxylic Acids / Q000494:pharmacology; D004195:Disease Models, Animal; D016291:Dizocilpine Maleate / Q000494:pharmacology; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D050491:Glutamate Plasma Membrane Transport Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005971:Glutamates / Q000378:metabolism; D006801:Humans; D051379:Mice; D009046:Motor Neurons / Q000378:metabolism / Q000502:physiology*; D014179:Neurotransmitter Uptake Inhibitors / Q000494:pharmacology; D011759:Pyrrolidines / Q000494:pharmacology; D017470:Receptors, Glutamate / Q000502:physiology*
D003998:Dicarboxylic Acids; D018691:Excitatory Amino Acid Antagonists; D050491:Glutamate Plasma Membrane Transport Proteins; D005971:Glutamates; D014179:Neurotransmitter Uptake Inhibitors; D011759:Pyrrolidines; D017470:Receptors, Glutamate; D016291:Dizocilpine Maleate; C083486:pyrrolidine-2,4-dicarboxylic acid