title: Assessment of sleep in women with night eating syndrome.
abstract: OBJECTIVE
  Evaluation of sleep in subjects with night eating syndrome (NES).
  
  
  METHODS
  Polysomnographic and questionnaire comparisons between subjects with NES and controls.
  
  
  METHODS
  Fifteen women with NES (mean +/- SD = 41 +/- 8 years) and 14 women (comparable age and weight) without NES (39 +/- 10 years) were studied in the laboratory for 3 days.
  
  
  METHODS
  N/A.
  
  
  RESULTS
  Subjects with NES did not differ from controls in timing of sleep onset or offset. They had less stage 2 sleep than controls (minutes, p = .012; percentage, p = .016) and less stage 3 sleep (p = .023), which contributed to their having a lower total sleep time (p = .05) and reduced sleep efficiency (p = .03). Subjects with NES did not have more awakenings than controls, but 93.3% of them ate on awakening during all 3 nights, while 92.9% of controls did not eat on any night. Logistic discriminant analyses identified a multiple sleep parameter model associated with increased likelihood of NES that had sensitivity of 84.6% and specificity of 76.9%. Patients with NES were more depressed than controls (p < .001) and reported greater sleep disturbance that included lower sleep quality (p < or = .001), reduced sleep duration (p < or = .001), and increased number of awakenings (p < or = .001).
  
  
  CONCLUSIONS
  Patients with NES appear to have sleep maintenance insomnia rather than sleep-related eating disorder or a parasomnia. The maintenance of normal timing for sleep-wake behavior in the presence of a phase delay in the timing of caloric intake suggests this disorder reflects a state of internal circadian desynchrony associated with significant sleep complaints. It remains unknown whether the sleep disturbance precedes the abnormally timed eating.
authors.affiliation: Division of Sleep and Chronobiology, Department of Psychiatry, The University of Pennsylvania School of Medicine, Philadelphia 19104-021, USA.
authors.forename: Naomi L
authors.initials: NL
authors.lastname: Rogers
authors.forename: David F
authors.initials: DF
authors.lastname: Dinges
authors.forename: Kelly C
authors.initials: KC
authors.lastname: Allison
authors.forename: Greg
authors.initials: G
authors.lastname: Maislin
authors.forename: Nicole
authors.initials: N
authors.lastname: Martino
authors.forename: John P
authors.initials: JP
authors.lastname: O'Reardon
authors.forename: Albert J
authors.initials: AJ
authors.lastname: Stunkard
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002940:Circadian Rhythm; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D017286:Polysomnography; D012894:Sleep Stages / Q000502:physiology*; D011795:Surveys and Questionnaires