title: Determination of urinary trace elements (arsenic, copper, cadmium, manganese, lead, zinc, selenium) in patients with Blackfoot disease.
abstract: To determine the relationship of arsenic, copper, cadmium, manganese, lead, zinc and selenium to Blackfoot disease (BFD, a peripheral vascular disorder endemic to areas of Taiwan, which has been linked to arsenic in drinking water) the authors measured the amount of these substances in urine from BFD patients, using atomic absorption spectrometry. Results indicate significantly higher amounts of urinary arsenic, copper, cadmium, manganese, and lead for BFD patients than for normal controls, also significantly lower urinary zinc and selenium.
authors.affiliation: Graduate Institute of Occupational Safety, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Jin-Lian
authors.initials: JL
authors.lastname: Tsai
authors.forename: Pin-Hua
authors.initials: PH
authors.lastname: Horng
authors.forename: Tzung-Jeng
authors.initials: TJ
authors.lastname: Hwang
authors.forename: John W
authors.initials: JW
authors.lastname: Hsu
authors.forename: Ching-Jyi
authors.initials: CJ
authors.lastname: Horng
mesh_terms: D001151:Arsenic / Q000652:urine*; D020261:Arsenic Poisoning / Q000453:epidemiology* / Q000209:etiology; D002104:Cadmium / Q000652:urine*; D016022:Case-Control Studies; D003300:Copper / Q000652:urine*; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D006801:Humans; D007854:Lead / Q000652:urine; D008297:Male; D008345:Manganese / Q000652:urine; D016491:Peripheral Vascular Diseases / Q000453:epidemiology* / Q000209:etiology; D012643:Selenium / Q000652:urine*; D013054:Spectrophotometry, Atomic; D013624:Taiwan / Q000453:epidemiology; D014874:Water Pollutants, Chemical / Q000009:adverse effects* / Q000652:urine; D015032:Zinc / Q000652:urine
chemical_list: D014874:Water Pollutants, Chemical; D002104:Cadmium; D007854:Lead; D008345:Manganese; D003300:Copper; D012643:Selenium; D015032:Zinc; D001151:Arsenic