title: [Development and application of thiophilic adsorption chromatography for antibody purification].
abstract: Thiophilic adsorption chromatography binds antibodies and other proteins in the presence of high concentration of salt. When eluted by decreasing the salt concentration, the high purity and recovery of proteins can be achieved. It is a new chromatographic technology for the purification of proteins. The review introduces the method for the purification of antibodies and covers the development and application of the original technology.
authors.affiliation: Life Science and Engineering College, Shaanxi University of Science and Technology, Xianyang 712081, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Liu
authors.forename: Hongxin
authors.initials: H
authors.lastname: Song
mesh_terms: D000327:Adsorption; D000485:Allergens / Q000276:immunology; D000818:Animals; D000906:Antibodies / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D002845:Chromatography / Q000379:methods*; D007074:Immunoglobulin G / Q000276:immunology*; D007136:Immunoglobulins / Q000276:immunology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D000485:Allergens; D000906:Antibodies; D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007136:Immunoglobulins; D012965:Sodium Chloride