Evaluation of the effectiveness of personal protective equipment against occupational exposure to N,N-dimethylformamide.
The objectives of this study were to evaluate the protective effectiveness of various personal protective equipment and the respective exposure contributions from respiratory and skin exposures of N,N-dimethylformamide (DMF) with a self-comparison study design. Two high-, four intermediate- and four low-DMF exposure workers from a synthetic leather factory were monitored in airborne DMF concentrations and N-methylformamide (NMF) concentrations in urine across four consecutive days. The workers were designated to wear no personal protective equipment on the first day. The barrier cream, rubber gloves and rubber gloves plus respirator were used on the second, third and fourth days, respectively. Person-to-personal observation was performed in the field to record all high and low exposure tasks during work for each subject. Protective effectiveness index (PEI) was used to evaluate different glove effectiveness. We concluded that the direct skin contact to the strong skin penetrates like DMF could be a more significant exposure source than the respiratory exposure in the actual occupational environment. The provision of protective equipment from skin exposure could be more important than that from respiratory exposure. The application of barrier cream could be as effective as wearing impermeable rubber gloves in the prevention from the skin penetrate in the occupational settings.
Wang
S-M
SM
Department of Environmental and Occupational Health, Medical College, National Cheng Kung University, Tainan, Taiwan, ROC.
Shih
T-S
TS
Huang
Y-S
YS
Chueh
M-R
MR
Chou
J-S
JS
Chang
H-Y
HY
D000328:Adult; D000395:Air Pollutants, Occupational / Q000032:analysis / Q000493:pharmacokinetics / Q000506:poisoning; D003710:Demography; D004126:Dimethylformamide / Q000008:administration & dosage / Q000032:analysis* / Q000493:pharmacokinetics / Q000506:poisoning; D004784:Environmental Monitoring; D006801:Humans; D007221:Industry; D019570:Inhalation Exposure; D016273:Occupational Exposure / Q000517:prevention & control*; D011482:Protective Devices / Q000592:standards*; D012867:Skin / Q000187:drug effects
D000395:Air Pollutants, Occupational; D004126:Dimethylformamide