Prevalence of erm genes encoding macrolide-lincosamide-streptogramin (MLS) resistance among clinical isolates of Staphylococcus aureus in a Turkish university hospital.
This study investigated the prevalence of the erm(A), erm(B) and erm(C) genes among 122 MLS-resistant clinical isolates of Staphylococcus aureus from a Turkish university hospital. Of these isolates, 44 were inducibly resistant and 78 were constitutively resistant. The presence of one or more erm genes was demonstrated in 114 isolates; the erm(C) gene was detected in 97 isolates, and the erm(A) gene was detected in 96 isolates. Seventy-eight isolates harboured both erm(A) and erm(C). The combination of erm(A), erm(B) and erm(C) genes was detected in only one isolate.
Saribas
Z
Z
Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. zsaribas@superonline.ca
Tunckanat
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Pinar
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D001426:Bacterial Proteins / Q000235:genetics*; D024901:Drug Resistance, Multiple, Bacterial; D006785:Hospitals, University; D006801:Humans; D055231:Lincosamides; D018942:Macrolides / Q000494:pharmacology; D008780:Methyltransferases / Q000235:genetics*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics*; D025382:Streptogramin Group B / Q000494:pharmacology
D001426:Bacterial Proteins; D055231:Lincosamides; D018942:Macrolides; D025382:Streptogramin Group B; D008780:Methyltransferases; C431709:ErmA protein, Bacteria