[Use of antiglaucoma therapy to reduce acute intraocular pressure rise following neodymium: YAG laser iridotomy in angle-closure glaucoma patients].
OBJECTIVE
To evaluate the efficacy of topical antiglaucoma therapy in reducing acute intraocular pressure (IOP) elevation after neodymium: Yag laser iridotomy.


METHODS
Primary angle-closure glaucoma (PACG) eyes were randomized to receive premedication with latanoprost and pilocarpine, brimonidine 0.2% and pilocarpine or only with pilocarpine before Yag laser iridotomy. Postoperative IOP changes were compared with Wilcoxon signed-ranks test using the fellow eyes in each group.


RESULTS
Postoperative pressure spikes were significantly lower in the groups of patients with local antiglaucoma therapy with pilocarpine than in the control group. Mean elevation of IOP was less in the groups of patients with local antiglaucoma therapy with pilocarpine at 2 hours postoperatively.


CONCLUSIONS
Local antiglaucoma therapy may reduce the acute IOP rise following Yag laser iridotomy in PACG eyes.
Novak-Laus
Katia
K
Klinika za ocne bolesti, Klinicka bolnica Sestre milosrdnice, Zagreb, Hrvatska.
Masnec-Paskvalin
Sanja
S
Korsić
Jadranka
J
Iveković
Renata
R
Zorić-Geber
Mia
M
Mandić
Zdravko
Z
D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D000068438:Brimonidine Tartrate; D004359:Drug Therapy, Combination; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007498:Iris / Q000601:surgery*; D053685:Laser Therapy; D000077338:Latanoprost; D008297:Male; D008875:Middle Aged; D008916:Miotics / Q000008:administration & dosage; D009798:Ocular Hypertension / Q000517:prevention & control*; D010862:Pilocarpine / Q000008:administration & dosage; D011183:Postoperative Complications / Q000517:prevention & control*; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage; D011810:Quinoxalines / Q000008:administration & dosage
D000959:Antihypertensive Agents; D008916:Miotics; D011461:Prostaglandins F, Synthetic; D011810:Quinoxalines; D010862:Pilocarpine; D000068438:Brimonidine Tartrate; D000077338:Latanoprost