title: Update on adolescent immunization: review of pertussis and the efficacy, safety, and clinical use of vaccines that contain tetanus-diphtheria-acellular pertussis.
abstract: Adolescents, who comprise 14% of the US population, are historically resistant to receiving health care. As a result, adolescents have low immunization rates and are becoming more susceptible to diseases that are preventable by vaccine, such as pertussis. The incidence of pertussis has increased during the past 25 years, with a notable shift in incidence from young children to adolescents and young adults. New vaccines that provide protection against pertussis for use in adolescents have been proven to be safe, effective, and cost-beneficial. Regional epidemics among infants and other vulnerable populations can be reduced or eliminated with improved immunity in adolescents.
authors.affiliation: School of Nursing, University of Missouri-Kansas City, 2220 Holmes, Kansas City, MO 64108, USA. wilsonTR@umkc.edu
authors.forename: Thad R
authors.initials: TR
authors.lastname: Wilson
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services; D017677:Age Distribution; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000009:adverse effects / Q000276:immunology*; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000009:adverse effects / Q000276:immunology*; D004198:Disease Susceptibility; D006801:Humans; D007115:Immunization Schedule; D007117:Immunization, Secondary; D015994:Incidence; D009722:Nurse Practitioners; D010567:Pertussis Vaccine / Q000009:adverse effects / Q000276:immunology*; D011159:Population Surveillance; D017410:Practice Guidelines as Topic; D011320:Primary Health Care; D012307:Risk Factors; D012449:Safety / Q000706:statistics & numerical data; D014481:United States / Q000453:epidemiology; D014611:Vaccination / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D014917:Whooping Cough / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D010567:Pertussis Vaccine