title: Oral surgery with fibrin sealants in patients with bleeding disorders: a case report.
abstract: Surgical treatment of patients with bleeding disorders requires careful planning. The use of fibrin sealants following a dental extraction in a patient with von Willebrand's disease is presented in this report. A female patient with von Willebrand's disease had an extraction of a maxillary right third molar. After evaluation by the surgeon and the hematologist, the surgery was performed with a topical application of fibrin sealant and systemic administration of antifibrinolytic drugs. Hemostasis was obtained without replacement of plasma clotting factor. New techniques of achieving hemostasis in patients with bleeding disorders using fibrin sealants have been successfully used in oral surgery without replacement of plasma clotting factors or changes in anticoagulant therapy.
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul School of Dentistry, Porto Alegre, RS, Brazil. bourguignon.filho@bol.com.br
authors.forename: Aguimar de Matos Bourguignon
authors.initials: Ade M
authors.lastname: Filho
authors.forename: Renato Schroder
authors.initials: RS
authors.lastname: dos Santos
authors.forename: José Renato
authors.initials: JR
authors.lastname: Costa
authors.forename: André Alberto Câmara
authors.initials: AA
authors.lastname: Puppin
authors.forename: Robson Almeida
authors.initials: RA
authors.lastname: de Rezende
authors.forename: Gilson Correia
authors.initials: GC
authors.lastname: Beltrão
mesh_terms: D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D016063:Blood Loss, Surgical / Q000517:prevention & control; D017742:Dental Care for Chronically Ill; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008964:Molar, Third / Q000601:surgery; D014081:Tooth Extraction; D014842:von Willebrand Diseases
chemical_list: D000933:Antifibrinolytic Agents; D015718:Fibrin Tissue Adhesive; D006490:Hemostatics