Voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis clinical trial.
In this study, the voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis trial were compared to their susceptibilities to fluconazole and griseofulvin. The MIC ranges of voriconazole, fluconazole, and griseofulvin, were 0.002 to 0.06 microg/ml, 0.25 to 32 microg/ml, and 0.125 to 2.0 microg/ml, respectively.
Ghannoum
M
M
Center for Medical Mycology, University Hospital of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA. mahmoud.ghannoum@uhhs.com
Isham
N
N
Sheehan
D
D
D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects* / Q000302:isolation & purification; D002986:Clinical Trials as Topic; D015725:Fluconazole / Q000494:pharmacology; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000494:pharmacology*; D014006:Tinea Capitis / Q000382:microbiology*; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D006118:Griseofulvin; D015725:Fluconazole; D065819:Voriconazole