title: Effect of moderate white wine consumption on serum IgA and plasma insulin under fasting conditions.
abstract: OBJECTIVE
  The present study aims to investigate the contribution of alcohol toxicity to the development of malnutrition by assessing the effect of consuming a moderate amount of white wine on plasma insulin and serum IgA under fasting conditions.
  
  
  METHODS
  A total of 5 non-alcoholic males aged between 19 and 22 years participated in the current investigation. The experimental procedure required participants to undergo a 6-hour fast before ingesting 4 standard units of alcohol (40 g) in the form of white wine over a 120-min period. The level of blood alcohol, plasma insulin and serum IgA was assessed at 30-min intervals across the 120-min experimental period.
  
  
  RESULTS
  Consuming alcohol promotes a significant increase in serum IgA in the absence of any change in plasma insulin or ketone production in fasted individuals.
  
  
  CONCLUSIONS
  White wine prior to a meal does not promote glucose metabolism and utilization and may increase the risk of developing a transient diabetic condition due to an alteration in energy metabolism.
authors.affiliation: School of Psychological Science, La Trobe University, Bendigo, Australia.
authors.forename: Anna
authors.initials: A
authors.lastname: Kokavec
authors.forename: Simon F
authors.initials: SF
authors.lastname: Crowe
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000704:Analysis of Variance; D019540:Area Under Curve; D001786:Blood Glucose; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D005215:Fasting / Q000097:blood; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007328:Insulin / Q000097:blood*; D007657:Ketone Bodies / Q000652:urine; D008297:Male; D014920:Wine
chemical_list: D001786:Blood Glucose; D007074:Immunoglobulin G; D007328:Insulin; D007657:Ketone Bodies