title: Periapatite may not improve micromotion of knee prostheses in rheumatoid arthritis.
abstract: Prosthesis migration in bone inevitably occurs in cemented and uncemented total knee arthroplasty tibial components. Cemented designs as the gold standard give immediate fixation whereas cementless designs need a period of bone ingrowth onto the surface irregularities of the implants. The addition of bioactive coatings may enhance this process of ingrowth. A controlled randomized prospective RSA study was carried out on 26 Duracon implants in a rheumatoid arthritis patient group to evaluate the effect of a periapatite coating on the fixation of the tibial tray. The coated and the noncoated groups were matched for sex, age, body mass index, and HSS Knee Score. Stage of preoperative joint destruction and preoperative and postoperative mechanical leg axis showed no differences. We saw no differences in migration between the two groups, but a trend for lesser translations along and rotations about all three axes in the periapatite group. The periapatite-coated components showed a lower variance in subsidence than did the uncoated components. Both groups also showed a high variance in anterior tilting of the components. The cementless PA-coated Duracon prosthesis used in patients with RA may provide improved fixation of tibial components although we could not demonstrate improvement in this small controlled series.
  
  
  METHODS
  Therapeutic Level II. See the Guidelines for Authors for a complete description of levels of evidence.
authors.affiliation: Department of Orthopaedic Surgery and Traumatology, Atrium Medisch Centrum, Heerlen, The Netherlands.
authors.forename: Matthys J A
authors.initials: MJ
authors.lastname: van der Linde
authors.forename: Eric H
authors.initials: EH
authors.lastname: Garling
authors.forename: Edward R
authors.initials: ER
authors.lastname: Valstar
authors.forename: Alfons J
authors.initials: AJ
authors.lastname: Tonino
authors.forename: Rob G H H
authors.initials: RG
authors.lastname: Nelissen
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee; D020099:Coated Materials, Biocompatible; D005260:Female; D005500:Follow-Up Studies; D005548:Foreign-Body Migration / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography
chemical_list: D020099:Coated Materials, Biocompatible