[Pathological character and treatment of epithelial-myoepithelial carcinoma of salivary gland].
OBJECTIVE
To review and evaluate pathologic features and treatment of epithelial-myoepithelial.


METHODS
Retrospectively reviewed 14 cases' pathological and clinical materials of epithelial-myoepithelial carcinoma of salivary gland. Eight cases origine from parotid gland, 2 cases from hard palate, 3 cases from submandibular gland and 1 case from nasal cavity. Three cases were performed induction chemotherapy preoperation. One case had palliative radiotherapy. Thirteen cases were performed radical surgery and 6 cases had radiotherapy postoperation.


RESULTS
Tumor arisen mostly from parotid gland and neck lymph node metastasis rate was 14.28% (2/14). The survival rate was calculated with Kaplan-Meier method. The overall 3-, 5- and 10-year survival rate were 67.20%, 45.49% and 17.06%. Its histological characteristics were inner layer composed by adenoid cells and outer layer composed by myoepithelial cells. Immunohistochemical exam show cytokeratin, S-100 and actin reaction positive.


CONCLUSIONS
Epithelial-myoepithelial carcinoma easily develops recurrence. It is sensitivity to radiotherapy and chemotherapy to some extent. It is suitable to adopt surgical treatment as primary modality combined with other therapies.
Li
Hao
H
Department of Head and Neck, Cancer Center, Sun Yat-sen University, Guangzhou, China.
Wu
Guo-hao
GH
Chen
Fu-jin
FJ
Zhang
Quan
Q
Wei
Mao-wen
MW
Chen
Wen-kuan
WK
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000628:therapy; D012469:Salivary Glands / Q000473:pathology