Residual risk of HIV, HVB and HCV transmission by blood transfusion between 2002 and 2004 at the Abidjan National Blood Transfusion Center.
The assessment of the viral residual risk from blood products is an assessment indicator of the quality management system and of the availability process of these products. Assessments of HIV, HBV and HCV viruses transmission risks through blood transfusion are calculated after the setting of a quality approach at the Abidjan NBTC. The method used estimates the risk of a donation made during a period immunologically silent. The residual risks for HIV, HBV, and HCV viruses have been estimated by multiplying the incidence rate for 100,000 people per year by the respective durations of the serological windows. The data received from the Abidjan Center's information processing system (Progesa 4.4d of MAK SYSTEM) go from 2002 to 2004 period. The residual risks are 1/5780 donations for HIV and 1/406 donations for the HCV, then 1/383 donations for the HBV. The residual risk for the HIV is almost four times reduced compared to that of 1997. The results show not only the importance of the transmission risk of HIV, HBV and HCV viruses through blood products, but also the necessity to set a quality management system in endemic countries of Sub-Saharan Africa.
Ouattara
H
H
Service d'endocrinologie et biologie de la reproduction, UFR biosciences, université de Cocody, 14 BP 840 Abidjan 14, Abidjan, Ivory Coast. houattara@cnts-ci.com
Siransy-Bogui
L
L
Fretz
C
C
Diane
K M
KM
Konate
S
S
Koidio
A
A
Minga
K A
KA
Hyda
J
J
Koffi-Abe
N
N
Offoumou
A M
AM
Abissey
S
S
D001803:Blood Transfusion / Q000592:standards*; D007560:Cote d'Ivoire / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology / Q000635:transmission*; D006509:Hepatitis B / Q000453:epidemiology / Q000635:transmission*; D006526:Hepatitis C / Q000453:epidemiology / Q000635:transmission*; D006801:Humans; D015994:Incidence; D018570:Risk Assessment; D065227:Transfusion Reaction