title: Rh(II)-catalyzed intramolecular C-H insertion of diazo substrates in water: scope and limitations.
abstract: Preferential Rh(II) carbenoid intramolecular C-H versus O-H insertion derived from alpha-diazo-acetamides can be achieved in water by using an appropriate combination of the catalyst and amide groups, which creates a larger hydrophobic environment around the reactive carbenoid center.
authors.affiliation: CQFM, Departamento de Engenharia Química, IST, 1049-001 Lisboa, Portugal.
authors.forename: Nuno R
authors.initials: NR
authors.lastname: Candeias
authors.forename: Pedro M P
authors.initials: PM
authors.lastname: Gois
authors.forename: Carlos A M
authors.initials: CA
authors.lastname: Afonso