title: [Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma].
abstract: OBJECTIVE
  The aim of the study was to analyze changes in intraocular pressure after Nd: YAG laser capsulotomy in pseudophakic patients with glaucoma.
  
  
  METHODS
  Intraocular pressure was recorded before, and 1 and 3 hours after YAG laser capsulotomy in 69 pseudophakic patients with glaucoma. Twenty eight patients received no therapy before capsulotomy, 21 patients received topical brimonidine 0.2%, and 20 patients received topical dorzolamide 2% 1 hour before laser capsulotomy. All patients received topical tropicamide 1% and tetracaine 0.5%. Nd: YAG laser posterior capsulotomy was performed using inverted-U technique to make a 3-4 mm diameter capsulotomy. After capsulotomy, all eyes received topical fluorometholone for 10 days.
  
  
  RESULTS
  A pressure rise was greater in patients without any therapy before YAG laser capsulotomy. Eight patients with glaucoma showed intraocular pressure rise of 5 mm Hg, and 2 patients pressure rise of 10 mm Hg after laser capsulotomy. A reduction of intraocular pressure rise was found in patients who received dorzolamide 2% or brimonidine 0.2%, only 1 patient in each group developed a pressure rise of 5 mm Hg. In all patients a significant pressure rise developed within the first hour.
  
  
  CONCLUSIONS
  It is difficult to compare different studies due to different techniques of cataract surgery and different intraocular lense material and design. Barnes showed that 6 of 29 (21%) developed a pressure rise of 5 mm Hg, and 1 of 29 (3%) patients a pressure rise of 10 mm Hg. In our study, 29% of patients had a pressure rise of > or =5 mm Hg, and 7% of patients had a rise of > or =10 mm Hg after laser capsulotomy. These results may be associated with a large proportion of extracapsular cataract extraction (71%) versus phacoemulsification (29%) in our patients.
  
  
  CONCLUSIONS
  Pretreatment with dorzolamide 2% or brimonidine 0.2% reduce the intraocular pressure rise after Nd: YAG laser capsulotomy in pseudophakic patients with glaucoma.
authors.affiliation: Odjel za ocne bolesti, Klinicka bolnica Mostar, Bosnai i Hercegovina.
authors.forename: Antonio
authors.initials: A
authors.lastname: Sesar
authors.forename: Irena
authors.initials: I
authors.lastname: Petric
authors.forename: Ivanka
authors.initials: I
authors.lastname: Sesar
authors.forename: Valentina
authors.initials: V
authors.lastname: Lacmnovic-Loncar
authors.forename: Darija
authors.initials: D
authors.lastname: Jurisić
authors.forename: Zeljka
authors.initials: Z
authors.lastname: Tomić
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
mesh_terms: D000287:Administration, Topical; D000959:Antihypertensive Agents / Q000008:administration & dosage; D000068438:Brimonidine Tartrate; D002387:Cataract Extraction; D005901:Glaucoma / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D053685:Laser Therapy; D007903:Lens Capsule, Crystalline / Q000601:surgery*; D011300:Preoperative Care; D019591:Pseudophakia / Q000150:complications*; D011810:Quinoxalines / Q000008:administration & dosage; D013449:Sulfonamides / Q000008:administration & dosage; D013876:Thiophenes / Q000008:administration & dosage
chemical_list: D000959:Antihypertensive Agents; D011810:Quinoxalines; D013449:Sulfonamides; D013876:Thiophenes; D000068438:Brimonidine Tartrate; C062765:dorzolamide