title: Vulvar angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma: an immunohistochemical and ultrastructural study.
abstract: To investigate the histogenetical unifying theory of a single, pluripotential primitive cell for vulvar angiomyxoma, aggresive angiomyxoma, and angiomyofibroblastoma, an optical, immunohistochemical and ultrastructural study of a superficial angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma was performed. These three tumors showed immunohistochemical and ultrastructural overlapping features. The results of the study suggest that these three tumor entities probably arise on a common pluripotential primitive cell located around the vessels of connective tissue, which could show the capacity for modulating its penotype toward similar but distinct mature cell types.
authors.affiliation: Department of Pathology, Hospital Universitari del Mar Universitat Autònoma de Barcelona, Barcelona, Catalunya, Spain. 86780@imas.imim.es
authors.forename: Francesc
authors.initials: F
authors.lastname: Alameda
authors.forename: Assumpció
authors.initials: A
authors.lastname: Munné
authors.forename: Teresa
authors.initials: T
authors.lastname: Baró
authors.forename: Mar
authors.initials: M
authors.lastname: Iglesias
authors.forename: Enric
authors.initials: E
authors.lastname: Condom
authors.forename: Josep
authors.initials: J
authors.lastname: Lloreta-Trull
authors.forename: Sergi
authors.initials: S
authors.lastname: Serrano
mesh_terms: D000328:Adult; D018229:Angiomyoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D046529:Microscopy, Electron, Transmission / Q000379:methods; D009232:Myxoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009379:Neoplasms, Muscle Tissue / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor