title: Catalyst recycling via hydrogen-bonding-based affinity tags.
abstract: [Structure: see text] A novel procedure for catalyst recycling is described. Copper(I)-based catalysts, equipped with an affinity tag, are isolated from crude reaction mixtures on the basis of quadruple hydrogen-bonding interactions using a resin functionalized with complementary affinity tags. Recycled catalysts were successfully used to catalyze a tandem Sonogashira coupling/5-endo-dig cyclization and a Cu-catalyzed [3+2] Huisgen cycloaddition reaction in high yields.
authors.affiliation: Institute for Molecules and Materials, Radboud University Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands.
authors.forename: Bas W T
authors.initials: BW
authors.lastname: Gruijters
authors.forename: Maarten A C
authors.initials: MA
authors.lastname: Broeren
authors.forename: Floris L
authors.initials: FL
authors.lastname: van Delft
authors.forename: Rint P
authors.initials: RP
authors.lastname: Sijbesma
authors.forename: Pedro H H
authors.initials: PH
authors.lastname: Hermkens
authors.forename: Floris P J T
authors.initials: FP
authors.lastname: Rutjes