title: SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes.
abstract: SNPmasker is a comprehensive web interface for masking large eukaryotic genomes. The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs. In addition to the SNP masking, we also offer population-specific substitution of SNP alleles in genomic sequence according to SNP frequencies in HapMap Phase II data. The input to SNPmasker can be defined in chromosomal coordinates or inserted as a sequence. The sequences masked by our web server are most useful as a preliminary step for different primer and probe design tasks. The service is available at http://bioinfo.ebc.ee/snpmasker/ and is free for all users.
authors.affiliation: Department of Bioinformatics, University of Tartu, Estonia.
authors.forename: Reidar
authors.initials: R
authors.lastname: Andreson
authors.forename: Tarmo
authors.initials: T
authors.lastname: Puurand
authors.forename: Maido
authors.initials: M
authors.lastname: Remm
mesh_terms: D000483:Alleles; D000818:Animals; D017931:DNA Primers; D030561:Databases, Nucleic Acid; D015894:Genome, Human; D023281:Genomics / Q000379:methods*; D006801:Humans; D020407:Internet; D051379:Mice; D015341:Nucleic Acid Probes; D020641:Polymorphism, Single Nucleotide; D012091:Repetitive Sequences, Nucleic Acid; D012984:Software; D014584:User-Computer Interface
chemical_list: D017931:DNA Primers; D015341:Nucleic Acid Probes