Decarboxylative ring contractions and olefin insertions of vinyl oxazinanones.
[Structure: see text] 6-Vinyl oxazinanones undergo catalytic, diastereoselective, decarboxylative ring contraction to form vinyl azetidines in good yield. Performing the decarboxylation in the presence of Michael acceptors results in decarboxylative olefin insertion to provide diastereoenriched substituted vinyl piperidines.
Wang
Chao
C
Department of Chemistry, University of Kansas, Lawrence, Kansas 66045, USA.
Tunge
Jon A
JA