Vasculitis associated with connective tissue disorders.
Vasculitis associated with connective tissue disorders is an important cause of secondary vasculitis about which little is written. When vasculitis occurs in the setting of a preexisting connective tissue disorder, it often correlates with disease severity and portends a poorer prognosis. It may involve virtually any organ system and present in a myriad of ways. Prompt recognition and treatment of vasculitis can dramatically improve the outcome for the patient. This review focuses on recent insights into the clinical presentation and pathogenic mechanisms that may be involved.
Doyle
Mittie K
MK
Centocor Research & Development, 200 Great Valley Parkway, Malvern, PA 19355, USA. mdoyle1@cntus.jnj.com
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D014657:Vasculitis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology