title: Crohn's disease of the esophagus: treatment of an esophagobronchial fistula with the novel liquid embolic polymer "onyx".
abstract: Esophageal involvement in Crohn's disease is very rare. In only a small subgroup of these patients -- up to date fourteen cases have been described in the literature -- the course of the illness may be complicated by esophageal fistula formation. The therapy for fistulizing esophageal Crohn's disease so far has been disappointing, recurrence and progression are likely, and surgery still is the primary treatment modality for refractory patients. We here present a case of severe Crohn's disease with an esophagobronchial fistula and the successful closure of the fistula tract with the novel liquid polymer sealant "Onyx". This approach offers a new option for the treatment of this rare complication of Crohn's disease and should be considered if surgery is not possible.
authors.affiliation: Department of Internal Medicine I, University of Regensburg. florian.rieder@klinik.uni-regensburg.de
authors.forename: F
authors.initials: F
authors.lastname: Rieder
authors.forename: O
authors.initials: O
authors.lastname: Hamer
authors.forename: C
authors.initials: C
authors.lastname: Gelbmann
authors.forename: J
authors.initials: J
authors.lastname: Schölmerich
authors.forename: V
authors.initials: V
authors.lastname: Gross
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
authors.forename: H
authors.initials: H
authors.lastname: Herfarth
authors.forename: G
authors.initials: G
authors.lastname: Rogler
mesh_terms: D000293:Adolescent; D001983:Bronchial Fistula / Q000175:diagnosis / Q000628:therapy*; D003424:Crohn Disease / Q000175:diagnosis* / Q000628:therapy*; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004621:Embolization, Therapeutic / Q000379:methods*; D004937:Esophageal Fistula / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008297:Male; D011145:Polyvinyls / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide