Testing for genetic structure in different urban Argentinian populations.
Fifteen autosomal short tandem repeat (STR) markers (D3S1358, HUMTH01, D21S11, D18S51, PENTA E, D5S818, D13S317, D7S820, D16S539, CSF1PO, PENTA D, HUMvWA, D8S1179, HUMTPOX, FGA) were analyzed in 1734 individuals living in urban areas of cities from six different Argentinian provinces (Buenos Aires, Neuquén, Tucumán, La Pampa, San Luis, Santa Cruz) in order to determine if a common urban database could be used in Argentina for forensic purposes. Frequencies estimates, Hardy-Weinberg equilibrium (HWE), and other parameters of forensic interest were computed. Comparisons between the six populations, and with published data from one Native American population from Argentina and other urban populations from Argentina and Europe were also performed. Our results reveal evidences for population structure, both when testing for genetic differentiation and when comparing frequencies distributions between different pairs of populations. Therefore, caution should be taken when using a common pooled database with general forensic purposes in Argentina.
Toscanini
Ulises
U
PRICAI-Fundacion Favaloro, Av. Belgrano 1782, 1er Subsuelo, 1093 Capital Federal, Buenos Aires, Argentina.
Gusmão
Leonor
L
Berardi
Gabriela
G
Amorim
António
A
Carracedo
Angel
A
Salas
Antonio
A
Raimondi
Eduardo
E
D001118:Argentina; D016172:DNA Fingerprinting / Q000379:methods*; D019992:Databases as Topic; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D014505:Urban Population