Incidence trends of prostate cancer in East Anglia, before and during the era of PSA diagnostic testing.
We investigated prostate cancer incidence in East Anglia from 1971 to 2000. Using age-period-cohort modelling, the number of cases expected in 1991-2000, based on pre-PSA trends, 1971-1990, was compared with that observed. Based on pre-1991 trends, 9203 new cases were expected in 1991-2000, but 9788 cases were observed, an excess of 6%.
Pashayan
N
N
Department of Public Health and Primary Care, Institute of Public Health, University Forvie Site, Cambridge, CB2 2SR, UK. np275@medschl.cam.ac.uk
Powles
J
J
Brown
C
C
Duffy
S W
SW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D004739:England / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology*; D012042:Registries; D012307:Risk Factors
D017430:Prostate-Specific Antigen