A long-time, high spatiotemporal resolution optical recording system for membrane potential activity via real-time writing to the hard disk.
Using real-time hard disk recording, we have developed an optical system for the long-duration detection of changes in membrane potential from 1,020 sites with a high temporal resolution. The signal-to-noise ratio was sufficient for analyzing the spreading pattern of excitatory waves in frog atria in a single sweep.
Hirota
Akihiko
A
Department of Neural and Muscular Physiology, Shimane University School of Medicine, Izumo, Shimane 693-8501, Japan. hirophy2@med.shimane-u.ac.jp
Ito
Shin-ichi
S
D000818:Animals; D016275:Atrial Function / Q000502:physiology; D004396:Coloring Agents; D003199:Computer Systems; D003201:Computers; D001330:Electronic Data Processing / Q000295:instrumentation / Q000379:methods*; D004594:Electrophysiology; D004867:Equipment Design; D006325:Heart Atria / Q000294:innervation; D008564:Membrane Potentials / Q000502:physiology*; D055095:Optics and Photonics; D011892:Rana catesbeiana; D012984:Software
D004396:Coloring Agents