Adverse outcome in women with thrombophilia and bilateral uterine artery notches.
Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher risk to have an adverse outcome than women without.
Grandone
Elvira
E
IRCCS Casa Sollievo della Sofferenza, S. Giovanni R. (FOGGIA), Foggia, Italy. e.grandone@operapadrepio.it
Colaizzo
Donatella
D
Martinelli
Pasquale
P
Paladini
Dario
D
di Minno
Giovanni
G
Margaglione
Maurizio
M
D000328:Adult; D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011446:Prospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D019851:Thrombophilia / Q000453:epidemiology*; D014599:Uterus / Q000098:blood supply*