title: Inhibitor development, immune tolerance and prophylaxis in haemophilia A--the need for an evidence-based approach.
authors.affiliation: Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital of Milan, Milan, Italy. piermannuccio.mannucci@unimi.it
authors.forename: P M
authors.initials: PM
authors.lastname: Mannucci
authors.forename: T
authors.initials: T
authors.lastname: Abshire
authors.forename: D
authors.initials: D
authors.lastname: Dimichele
authors.forename: E
authors.initials: E
authors.lastname: Santagostino
authors.forename: V
authors.initials: V
authors.lastname: Blanchette
mesh_terms: D019774:Blood Coagulation Factor Inhibitors / Q000097:blood*; D003029:Coagulants / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000276:immunology; D004334:Drug Administration Schedule; D019317:Evidence-Based Medicine; D005169:Factor VIII / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000276:immunology; D006467:Hemophilia A / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D007518:Isoantibodies / Q000097:blood; D008297:Male; D012307:Risk Factors
chemical_list: D019774:Blood Coagulation Factor Inhibitors; D003029:Coagulants; D007518:Isoantibodies; D005169:Factor VIII