Are elevated admission calcium levels associated with better outcomes after ischemic stroke?
Calcium (Ca(2+)) and magnesium (Mg(2+)) influence the molecular pathways of ischemic neuronal death. The authors evaluated the impact of admission serum Ca(2+) and Mg(2+) levels, on incident stroke severity and discharge functional outcome. After adjusting for covariates, higher admission Ca(2+) was significantly associated with lesser stroke severity and better discharge functional outcome. Admission Mg(2+) was not an independent clinical outcome prognosticator.
Ovbiagele
B
B
Stroke Center and Department of Neurology, UCLA Medical Center, USA. ovibes@mednet.ucla.edu
Liebeskind
D S
DS
Starkman
S
S
Sanossian
N
N
Kim
D
D
Razinia
T
T
Saver
J L
JL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002118:Calcium / Q000097:blood*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008274:Magnesium / Q000097:blood; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010343:Patient Admission / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020521:Stroke / Q000097:blood*
D008274:Magnesium; D002118:Calcium