[An oxygen pressure in hepatic tissue of experimental animals in modelling of obstructive jaundice and its treatment].
Efficacy of application of oxygen-transporting preparations in the treatment of obturation jaundice was studied. In experimental conditions while modelling obturation jaundice in animals there were revealed signs of failure of the oxygen delivery to hepatic cells, shown by significant lowering of the oxygen pressure (pO2) in hepatic tissue. To compensate such revealed disorders it is expedient to apply preparations, which owe oxygen-transporting function, such as perftoran or ozonized isotonic solution of sodium chloride. Incorporating perftoran and ozonized isotonic solution of sodium chloride in conventionally accepted complex impedes the tissue hypoxia occurrence, which starts after biliary system decompression, it promotes restoration of hepatic cells functional state in more early terms.
Sapegin
I D
ID
Khil'ko
S S
SS
Fomochkin
I I
II
D000818:Animals; D019299:Decompression, Surgical / Q000379:methods*; D004195:Disease Models, Animal; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage; D007552:Isotonic Solutions; D041781:Jaundice, Obstructive / Q000378:metabolism / Q000601:surgery*; D008099:Liver / Q000378:metabolism / Q000601:surgery*; D008297:Male; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D011817:Rabbits
D005466:Fluorocarbons; D007552:Isotonic Solutions; C063334:perftoran; D010100:Oxygen