Repeated arterial thrombosis as a complication of carboplatin-based chemotherapy.
We describe a case of a 57-year-old woman with repeated acute arterial thrombosis of the femoral arteries following intravenous carboplatin-based combination chemotherapy for metastatic ovarian carcinoma. By extensive workup, no other known causes of arterial thrombosis were found. To our knowledge, this is the first case describing arterial thrombosis occurring as a complication of carboplatin therapy.
Yeung
Kakkhee K
KK
Department of Vascular Surgery, VU University Medical Center, Amsterdam, the Netherlands.
Coster
Erwin
E
Floris Vos
A W
AW
Van der Vijgh
Roger K
RK
Linsen
Mattheus A M
MA
Wisselink
Willem
W
D000208:Acute Disease; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D016190:Carboplatin / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy; D011859:Radiography; D012008:Recurrence; D013927:Thrombosis / Q000139:chemically induced* / Q000000981:diagnostic imaging
D000970:Antineoplastic Agents; D016190:Carboplatin