title: Perception of emotional speech in Parkinson's disease.
abstract: Nonmotor symptoms in Parkinson's disease (PD) involving cognition and emotionality have progressively received attention. The objective of the present study was to investigate recognition of emotional prosody in patients with PD (n = 14) in comparison to healthy control subjects (HC, n = 14). Event-related brain potentials (ERP) were recorded in a modified oddball paradigm under passive listening and active target detection instructions. Results showed a poorer performance of PD patients in classifying emotional prosody. ERP generated by emotional deviants (happy/sad) during passive listening revealed diminished amplitudes of the mismatch-related negativity for sad deviants, indicating an impairment of early preattentive processing of emotional prosody in PD.
authors.affiliation: Department of Neurology, Medical School Hannover, Germany. schroeder.christinez@mh-hannover.de
authors.forename: Christine
authors.initials: C
authors.lastname: Schröder
authors.forename: Janine
authors.initials: J
authors.lastname: Möbes
authors.forename: Martin
authors.initials: M
authors.lastname: Schütze
authors.forename: Friedemann
authors.initials: F
authors.lastname: Szymanowski
authors.forename: Wido
authors.initials: W
authors.lastname: Nager
authors.forename: Marc
authors.initials: M
authors.lastname: Bangert
authors.forename: Thomas Frank
authors.initials: TF
authors.lastname: Münte
authors.forename: Reinhard
authors.initials: R
authors.lastname: Dengler
mesh_terms: D000368:Aged; D001288:Attention / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D032882:Comprehension; D003265:Contingent Negative Variation; D004569:Electroencephalography; D004644:Emotions / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013061:Speech Acoustics; D013067:Speech Perception / Q000502:physiology*