Interactions between Purkinje neurones and Bergmann glia.
Throughout the development of the cerebellar cortex, Purkinje neurones interact closely with Bergmann glial cells, a specialized form of astrocyte. This review summarizes the intimate developmental, anatomical and functional relationships between these two cell types, with particular emphasis on recent discoveries regarding glutamate release from climbing and parallel fibres as a pathway for signalling synaptic activity to Bergmann glia.
Bellamy
Tomas C
TC
Laboratory of Molecular Signalling, Babraham Institute, Babraham, Cambridge, UK.
D000818:Animals; D001253:Astrocytes / Q000166:cytology* / Q000502:physiology; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D002450:Cell Communication / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology; D002525:Cerebellar Cortex / Q000166:cytology / Q000196:embryology* / Q000254:growth & development*; D003712:Dendrites / Q000502:physiology / Q000648:ultrastructure; D018698:Glutamic Acid / Q000502:physiology; D006801:Humans; D011689:Purkinje Cells / Q000166:cytology* / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
D018698:Glutamic Acid