title: Iliopsoas haematoma in Gaucher disease.
abstract: Extrapelvis or retroperitoneal haemorrhage has long been appreciated as having many causes and considerable variability in subsequent morbidity; however, to date only two cases have been reported in patients with Gaucher disease, the most common lysosomal storage disorder. It had been our assumption that these cases were unique and a consequence of severe disease in patients who had not been treated with enzyme (or other disease-specific) therapy. Herein we present three more cases (as well as our first patient), which allow one to make some generalizations. Ultrasound was used in one centre and computed tomography in the second centre to make the definitive diagnosis. The trigger for the bleeding in all cases was muscle strain after activity. All patients were young with massive hepatosplenomegaly, anaemia, thrombocytopenia, and bone pain with skeletal involvement; the last was the most obvious commonality among these patients. Differential diagnosis is complicated by exquisite groin pain that is common to both Gaucher disease and extrapelvis haemorrhage, but not necessarily.
authors.affiliation: Institute for Orthopaedic Surgery and Traumatology, CCS, Belgrade, Serbia.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Lesić
authors.forename: Nada
authors.initials: N
authors.lastname: Suvajdzic
authors.forename: Ivo
authors.initials: I
authors.lastname: Elezovic
authors.forename: Marko
authors.initials: M
authors.lastname: Bumbasirevic
authors.forename: Irith
authors.initials: I
authors.lastname: Hadas-Halpern
authors.forename: Deborah
authors.initials: D
authors.lastname: Elstein
authors.forename: Ari
authors.initials: A
authors.lastname: Zimran
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005776:Gaucher Disease / Q000150:complications*; D006406:Hematoma / Q000209:etiology*; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal; D009135:Muscular Diseases / Q000209:etiology*; D016658:Psoas Muscles