title: Treatment of solitary gastric carcinoid tumor by endoscopic polypectomy in a patient with pernicious anemia.
abstract: Type I gastric carcinoid tumors result from hypergastrinemia in 1%-7% of patients with pernicious anemia. We diagnosed pernicious anemia in a 48-year-old female patient with complaint of fatigue for three months. She had no gastrointestinal symptoms. Endoscopic examination ot the upper gastrointestinal tract revealed atrophic gastritis and a polypoid lesion in the corpus of 3-4 mm in size. Endoscopic polypectomy was performed. Histopathological examination of the specimen revealed positive chromogranin A and synaptophysin stainings compatible with the diagnosis of a carcinoid tumor. Serum gastrin level was increased, urinary 5-hydroxyindoleacetic acid was within the normal range. There was no other symptom, sign, or laboratory finding of a carcinoid syndrome in the patient. No metastasis was found with indium-111 octreotide scan, computed tomographies of abdomen and thorax. Type I gastric carcinoid tumors are only rarely solitary and patients with tumors < 1 cm in size may benefit from endoscopic polypectomy.
authors.affiliation: Adnan Menderes University Medical Faculty, Division of Hematology, 09100 Aydin, Turkey. gurhan@medscape.com
authors.forename: Gurhan
authors.initials: G
authors.lastname: Kadikoylu
authors.forename: Irfan
authors.initials: I
authors.lastname: Yavasoglu
authors.forename: Vahit
authors.initials: V
authors.lastname: Yukselen
authors.forename: Esra
authors.initials: E
authors.lastname: Ozkara
authors.forename: Zahit
authors.initials: Z
authors.lastname: Bolaman
mesh_terms: D000752:Anemia, Pernicious / Q000150:complications*; D002276:Carcinoid Tumor / Q000209:etiology / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005755:Gastrins / Q000097:blood; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000601:surgery*; D013274:Stomach Neoplasms / Q000209:etiology / Q000601:surgery*
chemical_list: D005755:Gastrins