title: Significance of Rome II-defined functional constipation in Taiwan and comparison with constipation-predominant irritable bowel syndrome.
abstract: BACKGROUND
  The epidemiology and impact of functional constipation on Asians remain unclear.
  
  
  OBJECTIVE
  To determine the prevalence of functional constipation, its social/medical impact, and its distinction from constipation-predominant irritable bowel syndrome (C-IBS) in Taiwan.
  
  
  METHODS
  A Rome II questionnaire was administered to an apparently healthy adult Chinese population (n = 2865).
  
  
  RESULTS
  The prevalence of functional constipation was 8.5% and it was 2.7% for C-IBS. The functional constipation subjects were predominantly female and had excessive gastrointestinal-related doctor visits, absenteeism and sleep disturbance compared with controls (P < 0.01). Among functional constipation subjects, approximately 40% were 'consulters' with excessive doctor consultations, absenteeism and sleep disturbance. Female gender, the presence of sleep difficulty and higher constipation symptom scores were predictive of their consultation behaviour (P < 0.05). No differences existed in demographic variables, doctor consultations and absenteeism between 172 functional constipation and 54 C-IBS subjects. However, the C-IBS subjects experienced more severe constipation symptoms and sleep disturbance than functional constipation subjects.
  
  
  CONCLUSIONS
  Functional constipation in Taiwan is comparable with that in other countries. The clinical presentation of constipation-predominant irritable bowel syndrome differ somewhat from that of functional constipation.
authors.affiliation: Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine National Yang-Ming University, Taipei, Taiwan.
authors.forename: C-L
authors.initials: CL
authors.lastname: Lu
authors.forename: F-Y
authors.initials: FY
authors.lastname: Chang
authors.forename: C-Y
authors.initials: CY
authors.lastname: Chen
authors.forename: J-C
authors.initials: JC
authors.lastname: Luo
authors.forename: S-D
authors.initials: SD
authors.lastname: Lee
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D044466:Asian People / Q000208:ethnology; D003248:Constipation / Q000208:ethnology / Q000209:etiology*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D017678:Sex Distribution; D013624:Taiwan / Q000453:epidemiology