Fertility, pregnancy, and delivery after biventricular repair for pulmonary atresia with an intact ventricular septum.
The objective of the present study to investigate fertility, pregnancy, and delivery in women with biventricular repair for pulmonary atresia with an intact ventricular septum (PAIVS). Using a nationwide registry (CONCOR), 37 patients with pulmonary atresia were identified, 6 of whom (aged 21 to 34 years) had biventricular repair for PAIVS. Three PAIVS patients had a total of 5 pregnancies, including 1 abortion and 1 ectopic pregnancy. Besides minor noncardiac complications, the 3 live-birth pregnancies were successful. None of the women reported infertility or irregularities (hypermenorrhea, dysmenorrhea, polymenorrhoea, oligomenorrhea, or amenorrhea) of their natural menstrual cycle. In conclusion, successful pregnancy in women with biventricular repair for PAIVS is possible, and only minor complications were observed. Infertility and menstrual cycle disorders do not appear to be more prevalent than usual.
Drenthen
Willem
W
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands. w.drenthen@thorax.umcg.nl
Pieper
Petronella G
PG
Roos-Hesselink
Jolien W
JW
Zoon
Nicole
N
Voors
Adriaan A
AA
Mulder
Barbara J M
BJ
van Dijk
Arie P J
AP
Vliegen
Hubert W
HW
Sollie
Krystyna M
KM
Ebels
Tjark
T
van Veldhuisen
Dirk J
DJ
D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods*; D036861:Delivery, Obstetric; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006346:Heart Septum; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000601:surgery*; D011256:Pregnancy Outcome; D018633:Pulmonary Atresia / Q000601:surgery*