title: [Treatment for thyroid papillary cancer after nonstandard operation].
abstract: OBJECTIVE
  To evaluate the disadvantage of nonstandard operation for thyroid papillary cancer, and the value of re-operation.
  
  
  METHODS
  Eight hundred and ninety three thyroid papillary cancer patients (332 patients who received nonstandard operation received re-operation and 561 patients who received first standard operation in Zhejiang Cancer Hospital from January 1990 to January 2000) were retrospectively reviewed.
  
  
  RESULTS
  Pathological results confirmed that there were 53.9% cases with residual cancer in re-operative specimen. The parathyroid was preserved in 74.1% cases in re-operation and 93.0% cases in standard operation (P < 0.01). The recurrent laryngeal nerve was injured in 3.3% cases in reoperation and 1.2% cases in standard operation (P < 0.05). The positive neck lymph node was 39.2% and 37.4% (P > 0.05), the 5-year local recurrence rate was 7.5% and 3.7% (P < 0.01), the total 5-year and 10-year cum-survival rates were 90.2%, 84.4% in patients with re-operation and 94.0%, 92.5% in patients with standard operation. The 10-year cum-survival rate were 67. 8% in patients with recurrence and 92. 9% in patients with non-recurrence in primary site respectively. Statistical analysis showed that the cancer recurrence influences the survival rate significantly (P < 0.01).
  
  
  CONCLUSIONS
  In consideration of the higher residual tumor rate in patients who received nonstandard operations, the re-operations were necessary. But the re-operation could also leads to higher recurrence rate and more functional injuries. The standardized primary operation should therefore be formulated and advocated.
authors.affiliation: Department of Head and Neck Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China. gemingh@163.com
authors.forename: Ming-hua
authors.initials: MH
authors.lastname: Ge
authors.forename: Ai-hua
authors.initials: AH
authors.lastname: Liu
authors.forename: Ke-jing
authors.initials: KJ
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Guo
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Tan
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.forename: Jin-biao
authors.initials: JB
authors.lastname: Shang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D055815:Young Adult