Simple approach to beta-lactam derivatives from N-acylimidazoles.
Reaction of N-acylimidazoles possessing an electron-withdrawing group in the alpha position with diarylimines produces beta-lactams in high yields.
Nahmany
Moshe
M
Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel.
Melman
Artem
A
D000215:Acylation; D002384:Catalysis; D003500:Cyclization; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry*
D007093:Imidazoles; D047090:beta-Lactams