title: Doppler ultrasound signals simulation from vessels with various stenosis degrees.
abstract: As a non-invasive method, the Doppler ultrasound technique is used to detect the vessel stenosis. To search for characteristics of Doppler ultrasound signals sensitive to the stenosis, a computer simulation approach is proposed in this paper to generate Doppler ultrasound signals from vessels with various stenosis degrees. The blood flow velocity distribution in a stenosed vessel is firstly calculated using the transient finite element method (FEM). Then the power spectral density of Doppler signals is estimated using the overall-distribution nonparametric estimation method. Finally Doppler signals are generated using the cosine-superposed method. The proposed approach is proved to be useful for simulating Doppler ultrasound signals from vessels with various stenosis degrees. It is also shown that characteristics of Doppler ultrasound signals may be used to estimate the vessel's stenosis degree.
authors.affiliation: Department of Electronic Engineering, Fudan University, Shanghai 200433, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Fang
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Wang
authors.forename: Weiqi
authors.initials: W
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D000818:Animals; D001783:Blood Flow Velocity; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003198:Computer Simulation; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler / Q000295:instrumentation / Q000379:methods*