title: A general route to protected quaternary alpha-amino acids from beta-amino alcohols via a stereocontrolled radical approach.
abstract: A radical-based approach facilitates the highly stereocontrolled functionalisation of beta-amino alcohols, opening up a new, generally applicable methodology for the preparation of quaternary alpha-amino acids.
authors.affiliation: School of Biosciences (originally Department of Chemistry), University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, UKEX4 4QD. m.e.wood@exeter.ac.uk
authors.forename: Mark E
authors.initials: ME
authors.lastname: Wood
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Penny
authors.forename: Jenny S
authors.initials: JS
authors.lastname: Steere
authors.forename: Peter N
authors.initials: PN
authors.lastname: Horton
authors.forename: Mark E
authors.initials: ME
authors.lastname: Light
authors.forename: Michael B
authors.initials: MB
authors.lastname: Hursthouse
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D000605:Amino Alcohols / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D000605:Amino Alcohols