'Treatise on the Spinal Marrow and its Diseases' (Anatomy, functions and general considerations on its diseases) by Ollivier d' Angers CP (1796-1845).
METHODS
Collecting and analyzing all possible documents by internet, and consulting medical libraries in different countries.


OBJECTIVE
To focus on the work of Ollivier d'Angers who, in the beginning of the 19th century, spent most of his professional life studying the spinal cord, marrow (SM), or medulla spinalis, and publishing the first comprehensive treatise on the subject in 1824.


METHODS
ParaDoc database, Swiss Paraplegic-Centre, 6207 Nottwil, Switzerland, in collaboration with Paul Dollfus, ISCoS/Paradoc, Mulhouse, France.


RESULTS
Some of d'Angers's clinical descriptions, observations and also pathologic findings, described in the successive editions of his treatise, were very much in advance of his time.


CONCLUSIONS
To our knowledge, this was the first comprehensive treatise, in 1824, at least in France. It gave a clear picture on the matter of the SM and in that period of medical history.
Grossmann
S
S
ParaDoc, Swiss Paraplegic Center, Nottwil, Switzerland.
Maeder
I-M
IM
Dollfus
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P
D001855:Bone Marrow Diseases / Q000266:history*; D005602:France; D049671:History, 18th Century; D049672:History, 19th Century; D006801:Humans; D013122:Spinal Diseases / Q000266:history*