title: Factors affecting the bowel function after proctocolectomy and ileal J pouch-anal anastomosis for ulcerative colitis.
abstract: The aim was to study determinants of postoperative bowel function after restorative proctocolectomy for ulcerative colitis. Medical records of patients who underwent proctocolectomy with ileal J pouch-anal anastomosis (IPAA) in two- or three-stage operations and whose status of defecation was known via a questionnaire were retrospectively reviewed. Bowel function, including stool frequency, stool consistency, and degree of nighttime soiling, was correlated with age at the time of surgery, time after ileostomy closure, mean resting anal pressure, longitudinal length of ileal J pouch, and duration of fecal diversion by using univariate and multivariate analyses. Stool frequency decreased significantly with time after ileostomy closure in both univariate and multivariate analyses. Stool frequency tended to be less in patients having a long J pouch, but the correlation was not significant (P = 0.071) in univariate analysis. Nighttime soiling ameliorated with time after ileostomy closure in multivariate, but not univariate, analysis. Deterioration of nighttime soiling was seen in patients whose duration for fecal diversion was long, both in univariate (P = 0.068) and multivariate (P = 0.052) analyses. Stool consistency was related to none of the five factors investigated. These results indicate that as the time after surgery increases, stool frequency decreases and nighttime soiling ameliorates. Delaying ileostomy closure because of anticipated postoperative incontinence does not significantly alter postoperative continence.
authors.affiliation: Division of Biological Regulation and Oncology, Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan. cshibata@gonryo.med.tohoku.ac.jp
authors.forename: Chikashi
authors.initials: C
authors.lastname: Shibata
authors.forename: Yuji
authors.initials: Y
authors.lastname: Funayama
authors.forename: Kouhei
authors.initials: K
authors.lastname: Fukushima
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Fumito
authors.initials: F
authors.lastname: Saijo
authors.forename: Munenori
authors.initials: M
authors.lastname: Nagao
authors.forename: Sho
authors.initials: S
authors.lastname: Haneda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Kudoh
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kohyama
authors.forename: Iwao
authors.initials: I
authors.lastname: Sasaki
mesh_terms: D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical; D002648:Child; D003093:Colitis, Ulcerative / Q000503:physiopathology / Q000601:surgery*; D039021:Colonic Pouches; D003672:Defecation; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D041981:Gastrointestinal Tract / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016737:Proctocolectomy, Restorative / Q000009:adverse effects; D012189:Retrospective Studies; D013997:Time Factors