Exercise-induced intrapulmonary arteriovenous shunting and pulmonary gas exchange.
Recent research suggests the recruitment of intrapulmonary shunt vessels during exercise, which may contribute to the exercise-induced impairment in pulmonary gas exchange. These findings are consistent with substantial anatomical data demonstrating large-diameter (> 25 microm) anatomical shunts in the lung, but are contrary to the considerable functional gas exchange-dependent research that has not detected right-to-left physiological shunt during exercise.
Stickland
Michael K
MK
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706-1532, USA. stickland@wisc.edu
Lovering
Andrew T
AT
D000818:Animals; D001163:Arteriovenous Anastomosis; D004562:Electrocardiography; D015444:Exercise; D006736:Horses; D006801:Humans; D011652:Pulmonary Circulation; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D014922:Wisconsin