Management of colorectal cancer in older patients.
An increasing body of evidence suggests that geriatric patients can benefit from and tolerate standard chemotherapy similarly to younger patients in the settings of both early- and advanced-stage colorectal cancer. Assessment of this unique population requires more comprehensive evaluation in addition to routine history, physical examination, and laboratory tests. Specific considerations of their physiologic functional changes will help physicians better manage these patients. Ongoing studies are now designed to better understand the decisionmaking process, safety profile, and efficacy of various treatment regimens in geriatric patients.
Xiao
Han
H
Memorial Sloan-Kettering Cancer Center, Commack, New York 11725, USA.
Lichtman
Stuart M
SM
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D006801:Humans