[Hirschsprung-neurointestinal dyspasia: diferential diagnosis and reliability of diagnostic procedures].
The suspicion of Hirschsprung's disease (HD) or Neurointestinal Dysplasia (NID) arises with the appearance of a common symtomatology : delay in meconium evacuation, abdominal distention, vomiting, intestinal occlusion and ultimately, chronic constipation. The need to perform a correct differential diagnosis between both pathologies is essential, given that the treatment of HD is surgical while NID is expectant. The objective of this paper is to define the necessity of using or not all the diagnostic tests simultaneously to obtain a precise diagnosis. The authors performed a complete clinical review of a series of 42 HD and 18 NID analysing the results of diagnostic procedures (Radiology / transition zone, anorrectal manometry / absence of anal inhibitory reflex, and suction biopsy / AcHE study). The authors concluded that is necessary to perform all the three diagnostic procedures simultaneously in all patients with symtomatology given that not one test has the capacity to provide a diagnosis alone. Anorectal manometry has proven to be the most reliable test to diagnose HD. The authors agree with the guidelines published by Meier Ruge in 2004 to diagnose NID.
Gil-Vernet
J M
JM
Servicio de Cirugía Pediátrica, Unidad de Cirugía y Motilidad Digestiva, Hospital Universitario Materno-Infantil Vall d'Hebrón, Barcelona.
Broto
J
J
Guillén
G
G
D003248:Constipation / Q000175:diagnosis / Q000453:epidemiology; D003937:Diagnosis, Differential; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology; D006627:Hirschsprung Disease / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D008297:Male; D015203:Reproducibility of Results; D014839:Vomiting / Q000453:epidemiology