High-grade neuroendocrine carcinomas of the gallbladder and bile duct: Report of four cases with pathological correlation.
The extrahepatic biliary system is one of the unusual locations of extrapulmonary neuroendocrine carcinoma. To our knowledge, there has been no report describing the imaging findings of this rare malignancy of the biliary tree. We report 3 large-cell neuroendocrine carcinomas and a small-cell carcinoma arising from the biliary system. Biliary tumors showing on computed tomography an aggressive invasion to the liver or extensive lymph node involvement should raise the suspicion of their being high-grade neuroendocrine tumors.
Jun
Su Ryoung
SR
Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Chongno-gu, Seoul 110-744, Korea.
Lee
Jeong Min
JM
Han
Joon Koo
JK
Choi
Byung Ihn
BI
D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging* / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography