title: Database integration for predisposition genes discovery.
abstract: Lightweight and flexible data integration is nowadays a great challenge in biology. Databases size increased exponentially, and biologists need tools to extract and merge interesting data coming from several heterogeneous and distributed sources over the Internet. Furthermore, there is a great need for data mediation on grid computing architectures. This paper is about a demonstration which goal is to show how Mediation, a data integration technique, can help in building such bioinformatics tools. We focused on research of genes functions, especially those involved in the resistance to malaria or those that may be considered as predisposition genes.
authors.affiliation: LSIS, UMR 6168, Université Paul Cézanne Aix-Marseille 3. colonnaf@lsis.org
authors.forename: François-Marie
authors.initials: FM
authors.lastname: Colonna
authors.forename: Yacine
authors.initials: Y
authors.lastname: Sam
authors.forename: Omar
authors.initials: O
authors.lastname: Boucelma
mesh_terms: D019295:Computational Biology; D019992:Databases as Topic / Q000458:organization & administration*; D005060:Europe; D005796:Genes; D020407:Internet; D008969:Molecular Sequence Data; D018511:Systems Integration