Some probabilistic results on the nonrandomness of simple sequence repeats in DNA sequences.
Some probabilistic results on simple sequence repeats (SSRs) in DNA sequences are derived and used to quantify the nonrandomness of SSRs as an index of nonrandomness. The applicability of the index of nonrandomness is illustrated using several examples from the literature on selected human diseased genes.
Ndifon
Wilfred
W
Department of Biology, Morgan State University, Baltimore, MD 21251, USA. wndifon@princeton.edu
Nkwanta
Asamoah
A
Hill
Dwayne
D
D000465:Algorithms; D001483:Base Sequence / Q000235:genetics*; D006801:Humans; D000071058:Huntingtin Protein; D018895:Microsatellite Repeats / Q000235:genetics*; D008957:Models, Genetic; D015233:Models, Statistical; D009154:Mutation / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics; D011336:Probability; D011944:Receptors, Androgen / Q000235:genetics; D020754:Spinocerebellar Ataxias / Q000235:genetics; D020080:Tandem Repeat Sequences / Q000235:genetics
C410798:AR protein, human; C086055:HTT protein, human; D000071058:Huntingtin Protein; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D011944:Receptors, Androgen