[Cytometric characterization of the cell nucleus and nucleolus apparatus in dysplasia and exocervical cancer of the cervix uteri].
The morphometric parameters of the nucleonucleolar apparatus of the intact stratified squamous epithelium of the cervix uteri, dysplasias, and exocervical cancer were studied by computed morphometry of 50% silver nitrate solution-stained cytological specimens in order to study nucleolar organizers. It was shown that dysplastic changes and malignant transformation were marked by a progressive increase in the values of morphometric parameters of its nucleonucleolar apparatus. The staining of nucleolar organizers is relatively simple and it is expedient to use it for a specifying cytological diagnosis. The advantage of the staining is to identify rare atypical cells in cytological specimens.
Ievleva
N F
NF
Chizhova
G V
GV
Tsygankov
V I
VI
D000293:Adolescent; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology*; D002466:Cell Nucleolus / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009697:Nucleolus Organizer Region / Q000473:pathology*; D016622:Silver Staining; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology*; D014626:Vaginal Smears