[Etiologic analysis of globozoospermia: a 1-case report].
OBJECTIVE
To investigate the etiologic factors of globozoospermia.


METHODS
Routine semen analysis, sperm DNA special staining and chromosomal karyotype detection of peripherical blood lymphocytes were performed in a globozoospermia patient.


RESULTS
Round-headed spermatozoa were lack of acrosome and the acrosin activity was low. Meanwhile, there was an additional band located in the Y chromosomal short arm.


CONCLUSIONS
Lack of acrosome, low acrosin activity and abnormality of chromosome may be the main reasons for globozoospermia.
Shao
Yong
Y
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Hu
Yu-an
YA
Cui
Ying-xia
YX
Huang
Yu-feng
YF
D000176:Acrosin / Q000378:metabolism; D000328:Adult; D041322:Chromosomes, Human, Y / Q000235:genetics; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000235:genetics / Q000628:therapy; D008297:Male; D012729:Sex Chromosome Aberrations; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa / Q000002:abnormalities* / Q000648:ultrastructure
D000176:Acrosin