title: Asymmetric functionalization of gold nanoparticles with oligonucleotides.
abstract: Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.
authors.affiliation: Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.
authors.forename: Xiaoyang
authors.initials: X
authors.lastname: Xu
authors.forename: Nathaniel L
authors.initials: NL
authors.lastname: Rosi
authors.forename: Yuhuang
authors.initials: Y
authors.lastname: Wang
authors.forename: Fengwei
authors.initials: F
authors.lastname: Huo
authors.forename: Chad A
authors.initials: CA
authors.lastname: Mirkin
mesh_terms: D004247:DNA / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009841:Oligonucleotides / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D006046:Gold; D004247:DNA