Monocytic leukemia with cutaneous involvement: ultrastructural observations on unusual cytoplasmic complexes.
A case of pure monocytic leukemia ("true" histiocytic lymphoma) presented as multiple cutaneous nodules. The cells contained unusual cylindric formations of the rough endoplasmic reticulum that differ from classic ribosomal-lamellar complexes.
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Department of Pathology, The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Texas Medical Center, Houston, Texas 77030, USA.
Osborne
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Mackay
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D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D003561:Cytarabine / Q000008:administration & dosage; D018870:Endoplasmic Reticulum, Rough / Q000648:ultrastructure*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology*; D008727:Methotrexate / Q000627:therapeutic use; D046529:Microscopy, Electron, Transmission / Q000379:methods*; D008875:Middle Aged; D009113:Muramidase / Q000378:metabolism; D012270:Ribosomes / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology*; D013866:Thioguanine / Q000008:administration & dosage
D014408:Biomarkers, Tumor; D003561:Cytarabine; D002265:Carboxylic Ester Hydrolases; C021487:butyrylesterase; D009113:Muramidase; D013866:Thioguanine; D008727:Methotrexate