title: [Diagnosis and treatment of fibroadenoma of the breast: 20 years' experience].
abstract: The diagnostic differentiation of breast lesions is very important because of the frequency with which they occur. Though fibroadenoma is easy to diagnose, some cases prove really hard to distinguish. Therefore, various methods have been suggested both for diagnosis and therapy, but no common approach has been achieved to date. We report our experience with 1350 cases diagnosed over a twenty-year period. The diagnosis was made on the basis of a diagnostic protocol drawn up over the years where cytology is of primary importance. With regard to therapy, we decide to operate when the cytological findings prompt the need for a histological examination of the lesion. Moreover, we operate on those cases where either an increase in size or a morphological change of the lesion has taken place. Histological examinations were carried out in 420 cases out of 1350 and only one of these cases turned out to be a carcinoma. As a result, the 0.24% error in the diagnosis can be considered irrelevant. In spite of the different therapies suggested (cryoablation, laser hyperthermia, i.a.), we believe that surgical treatment with local anaesthetic is the most suitable solution in those cases requiring treatment. Obviously, the diagnosis has to be accurate and made by surgeons with appropriate expertise. When the diagnosis is certain and the conditions of the lesion are stable, the best policy seems to be periodic follow-up.
authors.affiliation: UOC Medicina Territoriale Chirurgica e Prevenzione Oncologica, Dipartimento di Chirurgia Pietro Valdoni, Università degli Studi di Roma La Sapienza, Roma.
authors.forename: Ersilia
authors.initials: E
authors.lastname: Ranieri
authors.forename: Simona
authors.initials: S
authors.lastname: Barberi
authors.forename: Giuliana
authors.initials: G
authors.lastname: Caprio
authors.forename: Liana
authors.initials: L
authors.lastname: Civitelli
authors.forename: Enzo
authors.initials: E
authors.lastname: Naticchioni
authors.forename: Francesca
authors.initials: F
authors.lastname: Ceccarelli
authors.forename: Mario
authors.initials: M
authors.lastname: Rengo
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D018226:Fibroadenoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D013997:Time Factors