title: Inhibition of lymphocyte proliferation in vitro by two lipid emulsions with different fatty acid compositions.
abstract: The effects of two lipid emulsions upon the proliferation of rat and human lymphocytes in vitro were investigated. The emulsions used were Intralipid, a soya bean oilbased emulsion in widespread clinical use, and Omegavenous, a newly-developed emulsion in which n-3 polyunsaturated fatty acids comprise approximately 40% of the total fatty acids. Both emulsions inhibited lymphocyte proliferation in a concentration- and time-dependent manner. Omegavenous was a much more potent inhibitor than Intralipid.
authors.affiliation: Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
authors.forename: P C
authors.initials: PC
authors.lastname: Calder
authors.forename: E J
authors.initials: EJ
authors.lastname: Sherrington
authors.forename: J
authors.initials: J
authors.lastname: Askanazi
authors.forename: E A
authors.initials: EA
authors.lastname: Newsholme