Hepatitis A and parvovirus B19 infections in an infant with fulminant hepatic failure.
Acute viral hepatitis with hepatitis A, B, C, D, and E viruses in the etiology of fulminant hepatic failure either single or in combinations has been described. Parvovirus B19 is also an etiologic agent of acute liver failure and hepatitis-associated aplastic anemia. We present a patient diagnosed with fulminant hepatitis A referred for liver transplantation. Parvovirus B19 superinfection was detected when the patient developed anemia during the course of the disease. We discuss possible roles of both viruses in fulminant hepatitis and pure red cell aplasia.
Ozçay
Figen
F
Department of Pediatric Gastroenterology, Başkent University, School of Medicine, Ankara, Turkey. fozcay@yahoo.com
Bikmaz
Y Emre
YE
Canan
Oğuz
O
Ozbek
Namik
N
D001856:Bone Marrow Examination; D002675:Child, Preschool; D017809:Fatal Outcome; D006506:Hepatitis A / Q000150:complications* / Q000175:diagnosis; D030041:Hepatitis A virus / Q000302:isolation & purification; D006801:Humans; D017114:Liver Failure, Acute / Q000175:diagnosis / Q000601:surgery / Q000821:virology*; D016031:Liver Transplantation; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications* / Q000175:diagnosis; D016732:Parvovirus B19, Human / Q000302:isolation & purification; D012010:Red-Cell Aplasia, Pure / Q000175:diagnosis / Q000821:virology*; D015163:Superinfection / Q000175:diagnosis / Q000821:virology*