Asymmetric functionalization of gold nanoparticles with oligonucleotides.
Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.
Xu
Xiaoyang
X
Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.
Rosi
Nathaniel L
NL
Wang
Yuhuang
Y
Huo
Fengwei
F
Mirkin
Chad A
CA
D004247:DNA / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009841:Oligonucleotides / Q000737:chemistry*
D009841:Oligonucleotides; D006046:Gold; D004247:DNA