title: [A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
abstract: We herein report a case of advanced gastric small cell carcinoma treated by chemotherapy and radiotherapy. A 69-year-old man was admitted to our hospital presenting with appetite loss and body weight loss. He was diagnosed to have an inoperable gastric small cell carcinoma with severe lymph node metastases and left adrenal gland metastasis. Chemotherapy with TS-1/paclitaxel, cisplatin/irinotecan and cisplatin/etoposide was sequentially performed. Primary and metastatic foci had obviously diminished. Eighteen months after the initial therapy, he had dysarthrosis and multiple brain metastases were found. Metastatic foci were decreased and his symptom was improved by successful radiotherapy. We conclude that chemotherapy and radiotherapy are effective for primary and metastatic lesions of gastric small cell carcinoma.
authors.affiliation: Dept. of Surgery, National Hospital Organization, Oita Medical Center.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Saeki
authors.forename: Go
authors.initials: G
authors.lastname: Anegawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Masuda
authors.forename: Ryuji
authors.initials: R
authors.lastname: Ohta
authors.forename: Masayuki
authors.initials: M
authors.lastname: Honda
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Kai
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kaneko
authors.forename: Hideaki
authors.initials: H
authors.lastname: Anai
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yokoyama
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000532:radiotherapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D005047:Etoposide; D000077146:Irinotecan; D017239:Paclitaxel; D002945:Cisplatin; D002166:Camptothecin