Diversity synthesis using the complimentary reactivity of rhodium(II)- and palladium(II)-catalyzed reactions.
Rhodium(II)-catalyzed reactions of aryldiazoacetates can be conducted in the presence of iodide, triflate, organoboron, and organostannane functionality, resulting in the formation of a variety of cyclopropanes or C-H insertion products with high stereoselectivity. The combination of the rhodium(II)-catalyzed reaction with a subsequent palladium(II)-catalyzed Suzuki coupling offers a novel strategy for diversity synthesis.
Ni
Aiwu
A
Department of Chemistry, University at Buffalo, State University of New York, Buffalo, New York 14260, USA.
France
Jessica E
JE
Davies
Huw M L
HM
D002384:Catalysis; D003508:Cycloheptanes / Q000138:chemical synthesis*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
D003508:Cycloheptanes; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D010165:Palladium; D012238:Rhodium