title: Postoperative recurrence in hepatocellular carcinoma: Comparison between percutaneous ethanol injection and radiofrequency ablation.
abstract: OBJECTIVE
  Recently percutaneous ethanol injection (PEI) turned into percutaneous radiofrequency ablation (PRFA), and it has become widely used for the treatment of hepatocellular carcinoma (HCC). The present study was to compare the incidence in postoperative HCC recurrence between these two therapeutic approaches.
  
  
  METHODS
  One hundred and sixty-eight first-time HCC in patient cases were chosen for PEI (n=94) and PRFA (n=74). The localized recurrence rate based on the operator's experience in percutaneous treatment for HCC (on <5 years versus >/=5 years experience) was examined.
  
  
  RESULTS
  The PRFA group demonstrated a significantly lower localized recurrence rate within 2 years than the PEI group (8% and 22%, respectively, P<0.01). The local recurrence rate of HCC within 2 years after PEI was significantly lower in those for whom the operator's experience was more than 5 years compared to those for whom it was less than 5 years (12% versus 24%, respectively, P<0.05). In contrast, after PRFA there was no significant difference between these two groups of <5 years and of >/=5 years experience (8% versus 8%, respectively, P=0.98).
  
  
  CONCLUSIONS
  The present study demonstrated that PRFA resulted in a lower rate of local recurrence in comparison to conventional PEI, regardless of the operator's experience.
authors.affiliation: Third Department of Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka City 814-0180, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Iwata
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Sohda
authors.forename: Shinya
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Nakane
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshikane
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Koyama
authors.forename: Daisuke
authors.initials: D
authors.lastname: Morihara
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Takeyama
authors.forename: Yuko
authors.initials: Y
authors.lastname: Uehara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kitamura
authors.forename: Makoto
authors.initials: M
authors.lastname: Irie
authors.forename: Satoshi
authors.initials: S
authors.lastname: Syakadou
authors.forename: Masanori
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kamimura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Watanabe
authors.forename: Shotaro
authors.initials: S
authors.lastname: Sakisaka