Electrocatalysis of oxygen at hemoglobin-Au colloid-1,4-benzenedimethanethiol modified electrode.
A novel renewable O2 sensor based on the direct electron transfer of hemoglobin (Hb) is proposed. Hb was immobilized on a gold nanoparticles (GNP) associated with a 1,4-benzenedimethanethiol (BDT) monolayer which were modified the electrode. The direct electrochemistry of Hb was investigated by electrochemical methods and cyclic voltammetric showing a pair of redox peaks of Hb. The high efficiency of the Hb/GNP/BDT modified gold electrode towards the catalytic electro-reduction of oxygen has been observed and the potential application of Hb/GNP/BDT modified gold electrode as biosensors to monitor O2 is proposed. The electrocatalytic response showed a linear dependence on the O2 concentration ranging from 2.0 to 40.0 micromol/L.
Wang
Guang-feng
GF
School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, PR China. guangfeng80wang@yahoo.com.cn
Deng
Xiang-hui
XH
Zhang
Wen-zhi
WZ
Fang
Bin
B
D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D003102:Colloids / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D006046:Gold / Q000737:chemistry*; D006454:Hemoglobins / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D015203:Reproducibility of Results; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D001555:Benzene Derivatives; D003102:Colloids; D006454:Hemoglobins; D013438:Sulfhydryl Compounds; D006046:Gold; C512626:1,4-benzenedimethanethiol; D010100:Oxygen