title: Diterpenes from the Far-eastern brown alga Dictyota dichotoma.
abstract: Two diterpenes, ent-erogorgiaene and (+)-1,5-cyclo-5,8,9,10-tetrahydroerogorgiaene, were isolated from the Russian Far-eastern population of the brown alga Dictyota dichotoma along with three previously known from this alga terpenoids. In addition, pentadecane was the first time isolated as natural product from this species. The structures of all compounds and their stereochemistry were determined using 1D and 2D NMR ((1)H-(1)H COSY, DEPT, HSQC, HMBC and NOESY), mass spectrometry, and optical rotation data.
authors.affiliation: Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku, 690022 Vladivostok, Russia.
authors.forename: Sophia A
authors.initials: SA
authors.lastname: Kolesnikova
authors.forename: Anatoly I
authors.initials: AI
authors.lastname: Kalinovsky
authors.forename: Sergei N
authors.initials: SN
authors.lastname: Fedorov
authors.forename: Larisa K
authors.initials: LK
authors.lastname: Shubina
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Stonik
mesh_terms: D000818:Animals; D002460:Cell Line; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D015394:Molecular Structure; D000459:Phaeophyceae / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D004224:Diterpenes; D010936:Plant Extracts; D012717:Sesquiterpenes