Toxin gene content of the Lyon methicillin-resistant Staphylococcus aureus clone compared with that of other pandemic clones.
The methicillin-resistant Staphylococcus aureus (MRSA) Lyon clone, detected throughout France, contains the enterotoxin A gene (sea), like other pandemic clones of clonal complex 8 (CC8). The egc locus was detected in MRSA pandemic clones of CC5, CC22, and CC45, occasionally with the toxic shock syndrome toxin 1 gene. The representative strain of the EMRSA-16 clone (CC30) harbored both sea and the egc locus.
Ferry
Tristan
T
Centre National de Référence des Staphylocoques, INSERM E0230, IFR 62, Faculté de Médecine Laennec, 7 rue Guillaume Paradin, 69008 Lyon, France. tristan.ferry@univ-lyon1.fr
Bes
Michèle
M
Dauwalder
Olivier
O
Meugnier
Hélène
H
Lina
Gerard
G
Forey
Françoise
F
Vandenesch
François
F
Etienne
Jerome
J
D001427:Bacterial Toxins / Q000235:genetics*; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D004768:Enterotoxins / Q000235:genetics; D005602:France; D005798:Genes, Bacterial; D006801:Humans; D016106:Methicillin Resistance; D016133:Polymerase Chain Reaction; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D018089:Superantigens / Q000235:genetics
D001427:Bacterial Toxins; D004269:DNA, Bacterial; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C026066:enterotoxin A, Staphylococcal