title: [3+2] cycloaddition reactions in the solid-phase synthesis of 1,2,3-triazoles.
abstract: [Structure: see text] An efficient and regioselective procedure for the synthesis of 1,2,3-triazoles via a [3+2] cycloaddition of polymer-bound vinyl sulfone and sodium azide is described. Microwave irradiation provided significant rate enhancement in all steps of the three-step protocol. A representative set of 23 compounds was prepared.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Yongnian
authors.initials: Y
authors.lastname: Gao
authors.forename: Yulin
authors.initials: Y
authors.lastname: Lam