Mitosis: disorderly conduct at the kinetochore.
Conventional models posit that microtubules bound to kinetochores act coordinately during chromosome movement. Such models need to be revised in the light of new data demonstrating uncoordinated behavior among kinetochore-associated microtubules.
Compton
Duane A
DA
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. duane.a.compton@dartmouth.edu
D000818:Animals; D023902:Chromosome Pairing / Q000502:physiology; D020090:Chromosome Segregation / Q000502:physiology; D033481:Chromosomes, Mammalian / Q000648:ultrastructure; D004330:Drosophila / Q000378:metabolism / Q000648:ultrastructure; D018386:Kinetochores / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D008322:Mammals / Q000033:anatomy & histology / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism / Q000648:ultrastructure; D008938:Mitosis / Q000502:physiology*; D008954:Models, Biological; D014057:Tomography, X-Ray Computed