Effect of moderate white wine consumption on serum IgA and plasma insulin under fasting conditions.
OBJECTIVE
The present study aims to investigate the contribution of alcohol toxicity to the development of malnutrition by assessing the effect of consuming a moderate amount of white wine on plasma insulin and serum IgA under fasting conditions.


METHODS
A total of 5 non-alcoholic males aged between 19 and 22 years participated in the current investigation. The experimental procedure required participants to undergo a 6-hour fast before ingesting 4 standard units of alcohol (40 g) in the form of white wine over a 120-min period. The level of blood alcohol, plasma insulin and serum IgA was assessed at 30-min intervals across the 120-min experimental period.


RESULTS
Consuming alcohol promotes a significant increase in serum IgA in the absence of any change in plasma insulin or ketone production in fasted individuals.


CONCLUSIONS
White wine prior to a meal does not promote glucose metabolism and utilization and may increase the risk of developing a transient diabetic condition due to an alteration in energy metabolism.
Kokavec
Anna
A
School of Psychological Science, La Trobe University, Bendigo, Australia.
Crowe
Simon F
SF
D000328:Adult; D000428:Alcohol Drinking; D000704:Analysis of Variance; D019540:Area Under Curve; D001786:Blood Glucose; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D005215:Fasting / Q000097:blood; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007328:Insulin / Q000097:blood*; D007657:Ketone Bodies / Q000652:urine; D008297:Male; D014920:Wine
D001786:Blood Glucose; D007074:Immunoglobulin G; D007328:Insulin; D007657:Ketone Bodies