Bringing order to early B cell chaos.
In the early 1990s, Richard (Randy) Hardy and colleagues divided B cell precursors into subpopulations--the Hardy fractions--based on the cells' expression of various cell surface proteins. This classification helped lay the groundwork for our present-day understanding of the molecular events that control early B cell development.
Van Epps
Heather L
HL
hvanepps@rockefeller.edu
D001402:B-Lymphocytes / Q000276:immunology / Q000502:physiology*; D049673:History, 20th Century; D006801:Humans; D013234:Stem Cells / Q000166:cytology / Q000276:immunology / Q000502:physiology*