title: Sister Mary Joseph's nodule originating from endometrial carcinoma incidentally detected during surgery for an umbilical hernia: a case report.
abstract: BACKGROUND
  Umbilical metastasis (Sister Mary Joseph's nodule) is rare. It is encountered in 1-3% of patients with intra-abdominal and/or pelvic malignancy, with gastric carcinoma being the commonest origin in men and ovarian carcinoma-in women. Only 27 cases of Sister Mary Joseph's nodule originating from endometrial carcinoma have previously been documented in the literature.
  
  
  METHODS
  In a 51-year-old woman, a Sister Mary Joseph's nodule coexisting with a large fibroid uterus was incidentally detected during surgery for suspected strangulated umbilical hernia. Subsequent laparotomy confirmed endometrial carcinoma metastasizing to the umbilical region.
  
  
  CONCLUSIONS
  This is the 28th case reported in the literature of Sister Mary Joseph's nodule originating from endometrial carcinoma and the first case of Sister Mary Joseph's nodule originating from endometrial carcinoma incidentally detected during surgery for umbilical hernia. Surgeons should be aware of the possibility of Sister Mary Joseph's nodule coexisting with an umbilical hernia.
authors.affiliation: Unit of Gynecologic Oncology, Department of Obstetrics and Gynecology, Soroka Medical Center and Faculty of Health Sciences, Cancer Research Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, 84101, Israel. piura@bgu.ac.il
authors.forename: Benjamin
authors.initials: B
authors.lastname: Piura
authors.forename: Mihai
authors.initials: M
authors.lastname: Meirovitz
authors.forename: Michael
authors.initials: M
authors.lastname: Bayme
authors.forename: Ruthy
authors.initials: R
authors.lastname: Shaco-Levy
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006554:Hernia, Umbilical / Q000473:pathology* / Q000601:surgery; D006801:Humans; D033162:Incidental Findings; D008875:Middle Aged; D009362:Neoplasm Metastasis; D014472:Umbilicus / Q000473:pathology*