title: [Cemented total knee arthroplasties].
abstract: BACKGROUND
  The aseptic loosening of cemented total knee arthroplasties is still an unsolved problem. In this regard, the hydrolysis resistance in the metal-to-bone cement interface is of major importance.
  
  
  METHODS
  Cemented pre-treated tibia components coated by means of a silica/silane interlayer system of the model "Columbus PS" were dynamically loaded with the help of a knee-simulator similar to DIN ISO 14243. After loading, the components were microscopically analysed concerning debonding in the metal-to-bone cement interface as well as with regard to cement mantle defects. These data were matched with uncoated "Columbus PS" components. Unloaded coated and uncoated tibia components acted as a control.
  
  
  RESULTS
  In comparison with uncoated tibia components, the pre-treated and coated ones yielded a highly significant reduction of cement defects (p < 0.01) as well as a significant reduction of debonding in the metal-to-bone cement interface (p < 0.05).
  
  
  CONCLUSIONS
  By means of the silica/silane interlayer system for cemented tibia components, a hydrolytic debonding in the metal-to-bone cement interface with subsequent mechanical loosening and consecutive early cement mantle failure can be significantly reduced. This could lead to an increased long-term stability of the metal-to-bone cement compound with decreased aseptic loosening in clinical use.
authors.affiliation: Orthopädie, Universitätsklinikum Aachen. Torsten.Mumme@GMX.de
authors.forename: T
authors.initials: T
authors.lastname: Mumme
authors.forename: R
authors.initials: R
authors.lastname: Marx
authors.forename: S
authors.initials: S
authors.lastname: Andereya
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: R
authors.initials: R
authors.lastname: Müller-Rath
authors.forename: D C
authors.initials: DC
authors.lastname: Wirtz
mesh_terms: D000268:Adhesiveness; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation* / Q000379:methods*; D001843:Bone Cements / Q000032:analysis* / Q000737:chemistry; D002484:Cementation / Q000379:methods; D019544:Equipment Failure Analysis; D007720:Knee Prosthesis; D008422:Materials Testing; D008670:Metals / Q000032:analysis* / Q000737:chemistry; D011474:Prosthesis Design
chemical_list: D001843:Bone Cements; D008670:Metals