A 47-year-old man with sudden onset of blindness, pleocytosis, and temporary hearing loss. Vogt-Koyanagi-Harada syndrome (Uveomeningoencephalitic syndrome).
The clinicopathologic findings of this patient were typical for Vogt-Koyanagi-Harada syndrome. Clinically, the patient had sudden onset of blindness, pleocytosis, and temporary hearing loss, with no history of eye trauma or surgery. Histopathologically, the choroid and iris showed chronic inflammation, loss of choroidal melanocytes, and dense chorioretinal adhesions. Presence of HLA-DRB1*0405 was consistent with the chronic phase of this syndrome.
Khoury
Thaer
T
Department of Pathology, State University of New York at Buffalo, USA. tk14216@yahoo.com
Gonzalez-Fernandez
Federico
F
Munschauer
Fredrick E
FE
Ostrow
Peter
P
D001766:Blindness / Q000473:pathology*; D002829:Choroid / Q000473:pathology; D017809:Fatal Outcome; D034381:Hearing Loss / Q000473:pathology*; D006801:Humans; D007498:Iris / Q000473:pathology; D007964:Leukocytosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D014607:Uveomeningoencephalitic Syndrome / Q000473:pathology*