[A case of advanced double cancer of the lung and stomach responding to combination chemotherapy of cisplatin and TS-1].
A 76-year-old male patient was diagnosed with advanced double cancer of the lung and stomach. He had also been suffering from interstitial pneumonitis for several years. He was treated with combination of cisplatin and TS-1. TS-1 (120 mg/body/day) was administered for 21 days from day 1, and cisplatin (60 mg/m(2)) was given on day 8 followed by a 14-days interval. After two courses of chemotherapy,the dose of cisplatin was reduced to 48 mg/m(2) because of grade 1 serum creatinine elevation. The lesions of the lung and stomach were improved significantly without exacerbation of the interstitial pneumonitis.
Sugawara
Aya
A
Dept. of Pulmonary Medicine, Fukushima Medical University School of Medicine.
Munakata
Kazue
K
Ishida
Takashi
T
Sato
Suguru
S
Yoshikawa
Motoko
M
Watanabe
Kana
K
Saito
Junpei
J
Ohtsuka
Yoshinori
Y
Munakata
Mitsuru
M
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy*; D010094:Oxonic Acid / Q000008:administration & dosage; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000008:administration & dosage
D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin