title: [Use of antiglaucoma therapy to reduce acute intraocular pressure rise following neodymium: YAG laser iridotomy in angle-closure glaucoma patients].
abstract: OBJECTIVE
  To evaluate the efficacy of topical antiglaucoma therapy in reducing acute intraocular pressure (IOP) elevation after neodymium: Yag laser iridotomy.
  
  
  METHODS
  Primary angle-closure glaucoma (PACG) eyes were randomized to receive premedication with latanoprost and pilocarpine, brimonidine 0.2% and pilocarpine or only with pilocarpine before Yag laser iridotomy. Postoperative IOP changes were compared with Wilcoxon signed-ranks test using the fellow eyes in each group.
  
  
  RESULTS
  Postoperative pressure spikes were significantly lower in the groups of patients with local antiglaucoma therapy with pilocarpine than in the control group. Mean elevation of IOP was less in the groups of patients with local antiglaucoma therapy with pilocarpine at 2 hours postoperatively.
  
  
  CONCLUSIONS
  Local antiglaucoma therapy may reduce the acute IOP rise following Yag laser iridotomy in PACG eyes.
authors.affiliation: Klinika za ocne bolesti, Klinicka bolnica Sestre milosrdnice, Zagreb, Hrvatska.
authors.forename: Katia
authors.initials: K
authors.lastname: Novak-Laus
authors.forename: Sanja
authors.initials: S
authors.lastname: Masnec-Paskvalin
authors.forename: Jadranka
authors.initials: J
authors.lastname: Korsić
authors.forename: Renata
authors.initials: R
authors.lastname: Iveković
authors.forename: Mia
authors.initials: M
authors.lastname: Zorić-Geber
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D000068438:Brimonidine Tartrate; D004359:Drug Therapy, Combination; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007498:Iris / Q000601:surgery*; D053685:Laser Therapy; D000077338:Latanoprost; D008297:Male; D008875:Middle Aged; D008916:Miotics / Q000008:administration & dosage; D009798:Ocular Hypertension / Q000517:prevention & control*; D010862:Pilocarpine / Q000008:administration & dosage; D011183:Postoperative Complications / Q000517:prevention & control*; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage; D011810:Quinoxalines / Q000008:administration & dosage
chemical_list: D000959:Antihypertensive Agents; D008916:Miotics; D011461:Prostaglandins F, Synthetic; D011810:Quinoxalines; D010862:Pilocarpine; D000068438:Brimonidine Tartrate; D000077338:Latanoprost