title: Cognitive control impairments in traumatic brain injury.
abstract: The componential nature of impaired cognitive control following traumatic brain injury (TBI) remains uncertain. We examined regulative and evaluative components of cognitive control in mild and moderate-to-severe (M/S) TBI patients and demographically-matched comparison participants using the AX-CPT task. We also examined relationships of cognitive control impairment to ratings of cognitive, behavioral, and affective symptomatology on the Dysexecutive Questionnaire (DEX). Results revealed that M/S, but not mild TBI patients showed deficits in context-processing and post-error strategic adjustments -- extent of impairments correlated with TBI-related symptomatology. Thus, patients with M/S TBI evidence cognitive control dysfunction in the processing and active maintenance of context representations.
authors.affiliation: Department of Clinical Psychology, University of Florida, Gainesville, FL 32610, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Larson
authors.forename: William M
authors.initials: WM
authors.lastname: Perlstein
authors.forename: Jason A
authors.initials: JA
authors.lastname: Demery
authors.forename: David A
authors.initials: DA
authors.lastname: Stigge-Kaufman
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001930:Brain Injuries / Q000503:physiopathology*; D003072:Cognition Disorders / Q000503:physiopathology*; D003710:Demography; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires