title: Fertility sparing options for breast cancer patients.
abstract: BACKGROUND
  Breast cancer is the most common malignancy to affect women of reproductive age. As more women are delaying fertility into the 4th and 5th decade of life, more women face the possibility of a breast cancer diagnosis prior to accomplishing their reproductive goals.
  
  
  METHODS
  Literature review PubMed, EMBASE.
  
  
  CONCLUSIONS
  From expectant management, hormonal suppression, in vitro fertilization with embryo freezing, to egg and ovarian tissue cryopreservation, numerous fertility sparing options are available to women with breast cancer. Therapy will be individualized based on a patient's age, financial resources, availability of services, cancer prognosis, ER/PR receptor, HER2 and BRCA status.
authors.affiliation: 101 Manning Drive, CB 7570, University of North Carolina, Chapel Hill, 27759, USA. ringland_murray@med.unc.edu
authors.forename: Ringland S
authors.initials: RS
authors.lastname: Murray
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics / Q000401:mortality / Q000503:physiopathology*; D015925:Cryopreservation; D005260:Female; D005298:Fertility / Q000187:drug effects / Q000528:radiation effects; D005307:Fertilization in Vitro; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists / Q000037:antagonists & inhibitors; D006801:Humans; D011379:Prognosis; D014019:Tissue Donors
chemical_list: D007987:Gonadotropin-Releasing Hormone