Sleep apnea in patients with myasthenia gravis.
To assess the prevalence of obstructive sleep apnea (OSA) in myasthenia gravis, the authors identified patients at risk of OSA using the multivariable apnea prediction index. OSA was diagnosed with polysomnography. The prevalence of OSA was 36% compared to an expected prevalence of 15 to 20% in the general population. When including the presence of daytime sleepiness (OSA syndrome), the prevalence was 11% compared to 3% in the general population.
Nicolle
M W
MW
Division of Neurology, Department of Medicine, University of Western Ontario, London, Ontario. mnicolle@uwo.ca
Rask
S
S
Koopman
W J
WJ
George
C F P
CF
Adams
J
J
Wiebe
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D003710:Demography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000453:epidemiology* / Q000503:physiopathology; D017286:Polysomnography / Q000379:methods; D015995:Prevalence; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000453:epidemiology* / Q000503:physiopathology