title: Voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis clinical trial.
abstract: In this study, the voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis trial were compared to their susceptibilities to fluconazole and griseofulvin. The MIC ranges of voriconazole, fluconazole, and griseofulvin, were 0.002 to 0.06 microg/ml, 0.25 to 32 microg/ml, and 0.125 to 2.0 microg/ml, respectively.
authors.affiliation: Center for Medical Mycology, University Hospital of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA. mahmoud.ghannoum@uhhs.com
authors.forename: M
authors.initials: M
authors.lastname: Ghannoum
authors.forename: N
authors.initials: N
authors.lastname: Isham
authors.forename: D
authors.initials: D
authors.lastname: Sheehan
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects* / Q000302:isolation & purification; D002986:Clinical Trials as Topic; D015725:Fluconazole / Q000494:pharmacology; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000494:pharmacology*; D014006:Tinea Capitis / Q000382:microbiology*; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D006118:Griseofulvin; D015725:Fluconazole; D065819:Voriconazole