title: Physiological range of peak cardiac power output in healthy adults.
abstract: OBJECTIVE
  The purpose of this study was to indicate the normal range for peak cardiac power output (CPO(peak)) in healthy adults and to explore age- and sex-related variations of this parameter.
  
  
  RESULTS
  Using the non-invasive exponential CO(2) rebreathing technique [J.G. Defares, J Appl Physiol13 (1958) 159], cardiac output was measured at an exercise intensity determined to coincide with > or =95% of peak oxygen consumption in 102 healthy adults (mean +/- SD, age 43 +/- 13 years, body mass 74 +/- 13 kg). Peak cardiac power was then computed from measurements of peak cardiac output (Q(Tpeak)) and peak mean arterial pressure (MAP(peak)) using the equation described by Cooke et al. [Heart79 (1998) 289]. Peak oxygen consumption in the study population was 2.42 (+/-0.74) l min(-1) and subjects achieved 101 +/- 7% of this value during the measurement of . was 17.3 (+/-4) l min(-1), and CPO(peak) was computed as 4.5 (+/-1.2) W. CPO(peak) ranged from 3.11 to 7.94 W in men and 2.53 to 5.57 W in women. Additionally, ageing appears to be associated with a significant loss of peak cardiac power in men that is not apparent in women.
  
  
  CONCLUSIONS
  Although the sample size remains moderate, the CPO values attained were normally distributed and these values provide a useful indication of the normal range for CPO(peak) in healthy adults.
authors.affiliation: Faculty of Health and Human Sciences, Thames Valley University, Slough, Berkshire, UK. paul.bromley@tvu.ac.uk
authors.forename: Paul D
authors.initials: PD
authors.lastname: Bromley
authors.forename: Lynette D
authors.initials: LD
authors.lastname: Hodges
authors.forename: David A
authors.initials: DA
authors.lastname: Brodie
mesh_terms: D000328:Adult; D000375:Aging; D001794:Blood Pressure; D001835:Body Weight; D002302:Cardiac Output; D004562:Electrocardiography; D015444:Exercise; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D012727:Sex Characteristics