Total synthesis of the marine natural product (-)-clavosolide A.
[Structure: see text] The total synthesis of the marine metabolite clavosolide A is reported which confirms the structure and absolute configuration of the natural product as the symmetrical diolide glycosylated by permethylated D-xylose moieties, 2.
Barry
Conor S
CS
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Elsworth
Jon D
JD
Seden
Peter T
PT
Bushby
Nick
N
Harding
John R
JR
Alder
Roger W
RW
Willis
Christine L
CL
D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D008386:Marine Biology; D015394:Molecular Structure; D013237:Stereoisomerism
D001688:Biological Products; D018942:Macrolides; C455699:clavosolide A