title: Down syndrome: common otolaryngologic manifestations.
abstract: Otolaryngologic or ear, nose, and throat (ENT) problems are common in children with Down Syndrome (DS). This includes problems with chronic ear infections and chronic middle ear effusions with associated hearing loss, airway obstruction, and sleep apnea, as well as problems with chronic rhinitis and sinusitis. In addition, many of these ENT problems require surgical interventions, and there are special anesthesia considerations that need to be addressed in children with DS. These include subglottic stenosis, post-operative airway obstruction, and cervical spine concerns. As the care of children with DS has become more consistent and proactive, outcomes from the treatment of these ENT manifestations have improved. Aggressive interventions, both medical and surgical, have led to a decreased incidence of hearing loss, good control of the chronic rhinitis, and a better awareness of the incidence of sleep apnea and sleep-disordered breathing in individuals with DS. These common otolaryngologic manifestations of DS are reviewed with recommendations for ongoing care and monitoring.
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Sally.Shott@cchmc.org
authors.forename: Sally R
authors.initials: SR
authors.lastname: Shott
mesh_terms: D000758:Anesthesia / Q000379:methods; D002648:Child; D004314:Down Syndrome / Q000150:complications*; D004424:Ear Canal / Q000002:abnormalities; D034381:Hearing Loss / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006320:Hearing Tests; D006801:Humans; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D017410:Practice Guidelines as Topic; D012220:Rhinitis / Q000209:etiology / Q000628:therapy; D012852:Sinusitis / Q000209:etiology / Q000628:therapy; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000209:etiology / Q000628:therapy