title: [Anaplastic thyroid carcinoma: aggressive radical resection and cervical reconstruction. A case report].
abstract: OBJECTIVE
  Anaplastic carcinoma of the thyroid is a rare but highly malignant tumor. The goal of this study was to present the case of a patient who underwent a multimodal treatment and to analyze prognosis factors.
  
  
  METHODS
  We present the case of a patient treated in 1996 for an anaplasic thyroid carcinoma with cervical cutaneous invasion. The initial surgical procedure was a total thyroidectomy extended to the anterior cervical skin associated to bilateral neck dissection. The patient underwent a differed reconstruction with musculocutaneous latissimus dorsi flap. Management was then supplemented by radiotherapy and chemotherapy.
  
  
  RESULTS
  This patient is free of tumor 9 years after this multimodal management. She does not present any functionary sequela and plastic results of the reconstruction is considered as very satisfactory.
  
  
  CONCLUSIONS
  Anaplastic carcinoma is one of more aggressive neoplasm affecting humans. This case report suggests that multimodality therapy, including surgery, chemotherapy and radiotherapy may offer hope for long-term survival. A musculocutaneous latissimus dorsi flap is a reliable solution to cover this large cervical defect.
authors.affiliation: Service de Chirurgie Plastique et Reconstructrice, Centre Léon-Bérard, 28, rue Laennec, 69007 Lyon, France. cathy251@9online.fr
authors.forename: A-C
authors.initials: AC
authors.lastname: Collin
authors.forename: K
authors.initials: K
authors.lastname: Chekaroua
authors.forename: T
authors.initials: T
authors.lastname: Delaporte
authors.forename: J-P
authors.initials: JP
authors.lastname: Droz
authors.forename: J-L
authors.initials: JL
authors.lastname: Peix
authors.forename: E
authors.initials: E
authors.lastname: Delay
mesh_terms: D002277:Carcinoma / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation; D037981:Neck Dissection / Q000379:methods*; D018714:Radiotherapy, Adjuvant; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*