title: Previous caesarean or vaginal delivery: which mode is a greater risk of perinatal death at the second delivery?
abstract: OBJECTIVE
  To compare the risk of perinatal death after previous caesarean versus previous vaginal delivery, and pre-labour repeat caesarean versus trial of labour after previous caesarean.
  
  
  METHODS
  Using the data of the Berlin Perinatal Registry from 1993 to 1999, 7556 second parous women with a previous caesarean delivery were compared with 55142 second parous women with a previous vaginal delivery, and those 1435 women with pre-labour repeat caesarean were compared with 6121 women with a trial of labour after previous caesarean delivery. The rates of perinatal death, stillbirth and intrapartum/neonatal death were analysed using multivariable logistic regression to adjust for confounding variables and obstetric history.
  
  
  RESULTS
  A previous caesarean delivery was associated with a 40% excess risk of perinatal death and a 52% excess risk of stillbirth (p<0.05); the risk of intrapartum/neonatal death was not significantly increased. There were no significantly higher rates of intrapartum/neonatal death and of stillbirth in women trying a vaginal birth versus pre-labour repeat caesarean. But in most cases of antepartum death, labour was induced for that reason.
  
  
  CONCLUSIONS
  Consulting women about caesarean delivery for maternal request, the increased risk of perinatal death in further pregnancies should be discussed. After a previous caesarean delivery, a careful screening for several risk factors is necessary before recommending a trial of labour.
authors.affiliation: Department of Obstetrics, Charité-Universitaetsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany. rolf.richter@charite.de
authors.forename: Rolf
authors.initials: R
authors.lastname: Richter
authors.forename: Renate L
authors.initials: RL
authors.lastname: Bergmann
authors.forename: Joachim W
authors.initials: JW
authors.lastname: Dudenhausen
mesh_terms: D001604:Berlin / Q000453:epidemiology; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012306:Risk; D050497:Stillbirth; D014219:Trial of Labor; D016064:Vaginal Birth after Cesarean / Q000401:mortality*