Stereochemical relays: communication via conformation.
Stereochemistry is information, and stereoselective reactions are the means by which that information may be communicated within and between molecules. The control of remote stereogenic centres can be achieved by stereochemical relay, and the use of thermodynamic control over conformational preference is turning out to be a very powerful method for long-range transmission of stereochemical information.
Clayden
Jonathan
J
School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. clayden@man.ac.uk
Vassiliou
Neoclis
N
D000577:Amides / Q000737:chemistry; D003500:Cyclization; D007700:Kinetics; D008024:Ligands; D008968:Molecular Conformation; D009930:Organic Chemicals / Q000737:chemistry*; D013237:Stereoisomerism; D013816:Thermodynamics; D014966:Xanthenes / Q000737:chemistry
D000577:Amides; D008024:Ligands; D009930:Organic Chemicals; D014966:Xanthenes