[Prevalence of putative periodontal microorganisms in Chinese patients with aggressive periodontitis].
OBJECTIVE
To evaluate the prevalence of putative periodontal microorganism in Chinese patients with aggressive periodontitis (AgP).


METHODS
A total of 72 subgingival plaque samples were collected from 55 AgP patients and 17 healthy subjects. Seven putative periodontal microorganisms including Actinobacillus actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythensis (Tf), Treponema denticola (Td), Campylobacter rectus (Cr), Prevotella intermedia (Pi) and Prevotella nigrescens (Pn) were detected by using 16S rRNA based polymerase chain reaction (PCR).


RESULTS
The prevalence of Aa in AgP patients was very low (1.8%), while Pg, Tf, Td and Cr were more frequently detected in AgP patients (prevalence: 81.8%, 83.6%, 80% and 81.8%) than in healthy controls (prevalence: 17.6%, 11.8%, 5.9%, 29.4%, P < 0.01).


CONCLUSIONS
The prevalence of Pg, Tf, Td and Cr were very high in aggressive periodontitis patients, and the combination of these bacteria may play an important role in AgP.
Feng
Xiang-hui
XH
Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Zhang
Li
L
Meng
Huan-xin
HX
Xu
Li
L
Chen
Zhi-bin
ZB
Shi
Dong
D
D000293:Adolescent; D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification*; D010520:Aggressive Periodontitis / Q000382:microbiology*; D015373:Bacterial Typing Techniques; D044883:Campylobacter rectus / Q000302:isolation & purification; D016022:Case-Control Studies; D003773:Dental Plaque / Q000382:microbiology*; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D048373:Treponema denticola / Q000302:isolation & purification; D055815:Young Adult