title: The epidemic threshold of vector-borne diseases with seasonality: the case of cutaneous leishmaniasis in Chichaoua, Morocco.
abstract: Cutaneous leishmaniasis is a vector-borne disease transmitted to humans by sandflies. In this paper, we develop a mathematical model which takes into account the seasonality of the vector population and the distribution of the latent period from infection to symptoms in humans. Parameters are fitted to real data from the province of Chichaoua, Morocco. We also introduce a generalization of the definition of the basic reproduction number R (0) which is adapted to periodic environments. This R (0) is estimated numerically for the epidemic in Chichaoua; approximately 1.94. The model suggests that the epidemic could be stopped if the vector population were reduced by a factor approximately 3.76.
authors.affiliation: IRD, 32 avenue Henri Varagnat, Bondy 93143, France. bacaer@bondy.ird.fr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Bacaër
authors.forename: Souad
authors.initials: S
authors.lastname: Guernaoui
mesh_terms: D000818:Animals; D004196:Disease Outbreaks / Q000706:statistics & numerical data; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology* / Q000635:transmission; D008433:Mathematics; D008954:Models, Biological; D009018:Morocco / Q000453:epidemiology; D011576:Psychodidae / Q000469:parasitology; D012621:Seasons