Recurrent superior mediastinal primary hemangiopericytoma 23 years after the complete initial excision: a case report.
We describe here a patient with a recurrent hemangiopericytoma of the superior mediastinum 23 years after an initial complete resection. In the current biopsy specimen, the tumor cells were much more anaplastic than those seen 23 years ago. Although the patient was treated with chemotherapy, which consisted of ifosfamide and epirubicin, the tumor was unresponsive and he died 6 months later from disease progression. Careful long-term follow-up is mandatory for patients with hemangiopericytomas because recurrence with greater malignancy can develop following an extended disease-free interval.
Hiraki
Akio
A
Department of Respiratory Medicine, NHO Sanyo National Hospital, Respiratory Disease Center, Ube, Yamaguchi 755-0241, Japan.
Murakami
Tomoyuki
T
Aoe
Keisuke
K
Matsuda
Eisuke
E
Maeda
Tadashi
T
Uemori
Yoshiki
Y
Ueoka
Hiroshi
H
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018450:Disease Progression; D015251:Epirubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006393:Hemangiopericytoma / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors
D015251:Epirubicin; D007069:Ifosfamide