title: DNA tile based self-assembly: building complex nanoarchitectures.
abstract: DNA tile based self-assembly provides an attractive route to create nanoarchitectures of programmable patterns. It also offers excellent scaffolds for directed self-assembly of nanometer-scale materials, ranging from nanoparticles to proteins, with potential applications in constructing nanoelectronic/nanophotonic devices and protein/ligand nanoarrays. This Review first summarizes the currently available DNA tile toolboxes and further emphasizes recent developments toward self-assembling DNA nanostructures with increasing complexity. Exciting progress using DNA tiles for directed self-assembly of other nanometer scale components is also discussed.
authors.affiliation: Department of Chemistry and Biochemistry and The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
authors.forename: Chenxiang
authors.initials: C
authors.lastname: Lin
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Sherri
authors.initials: S
authors.lastname: Rinker
authors.forename: Hao
authors.initials: H
authors.lastname: Yan
mesh_terms: D001482:Base Composition; D001703:Biophysics / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D008024:Ligands; D008968:Molecular Conformation; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods; D009690:Nucleic Acid Conformation; D017785:Photons; D040081:Protein Array Analysis; D011506:Proteins / Q000737:chemistry
chemical_list: D008024:Ligands; D011506:Proteins; D004247:DNA