title: The breakdown of bilayer lipid membranes by dendrimers.
abstract: The BLM-system for studying the electrophysical properties of bilayer lipid membranes (BLM) was applied to investigate interactions between polyamidoamine (PAMAM) dendrimers and lipid bilayers. The cationic PAMAM G5 dendrimer effectively disrupted planar phosphatidylcholine membranes, while the hydroxyl PAMAM-OH G5 and carboxyl PAMAM G4.5 dendrimers had no significant effect on them.
authors.affiliation: Department of General Biophysics, University of Łódź, Łódź, Poland.
authors.forename: Dzmitry
authors.initials: D
authors.lastname: Shcharbin
authors.forename: Alexander
authors.initials: A
authors.lastname: Drapeza
authors.forename: Valeri
authors.initials: V
authors.lastname: Loban
authors.forename: Alexej
authors.initials: A
authors.lastname: Lisichenok
authors.forename: Maria
authors.initials: M
authors.lastname: Bryszewska
mesh_terms: D050091:Dendrimers / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry
chemical_list: D050091:Dendrimers; D008051:Lipid Bilayers; C104700:PAMAM Starburst; D011073:Polyamines