title: [Vaginal colonization of the Streptococcus agalactiae in pregnant woman in Tunisia: risk factors and susceptibility of isolates to antibiotics].
abstract: Streptococcus agalactiae or Group B Streptococcus (GBS) is one of the main bacterial causes of serious infections in newborns. We have evaluated prospectively GBS vaginal colonization in pregnant women and we have tried to determine the risk factors of the colonization by GBS and the particularities of the different isolated strains. We have screened 300 pregnant women with vaginal and anal sample in a same swab. Thirty nine (13%) pregnant women are colonized by SGB, 0% in the first trimester, 10.2% in the second trimester and 17% in the third trimester. Different factors are associated significantly with GBS colonization: past history of infection in newborns, genital infection during pregnancy and parity The highest rates of resistance are found in tetracycline (97.4%), erythromycin (51.3%) and lincomycin (46.2%). All the strains were susceptible to amoxicilin and pristinamycin.
authors.affiliation: Laboratoire de miaobiologie et d'immunologie, UR 16/02, CHU F. Hached, Sousse 4001, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Ferjani
authors.forename: H
authors.initials: H
authors.lastname: Ben Abdallah
authors.forename: N
authors.initials: N
authors.lastname: Ben Saida
authors.forename: C
authors.initials: C
authors.lastname: Gozzi
authors.forename: J
authors.initials: J
authors.lastname: Boukadida
mesh_terms: D000293:Adolescent; D000328:Adult; D004917:Erythromycin; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008034:Lincomycin; D008826:Microbial Sensitivity Tests; D010298:Parity; D011247:Pregnancy; D012307:Risk Factors; D013290:Streptococcal Infections; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000254:growth & development* / Q000302:isolation & purification; D013753:Tetracycline Resistance; D014416:Tunisia; D014621:Vagina / Q000382:microbiology*
chemical_list: D004917:Erythromycin; D008034:Lincomycin