title: A novel butenoate derivative from Aspergillus niger.
abstract: A novel butenoate derivative, methyl (Z)-4-{[(Z)-1-(hydroxymethyl)-2-phenyl-1-ethenyl] amino}-4-oxo-2-butenoate (1), was isolated from the fermentation broth of an Aspergillus niger strain Ta1. The structure (1) was elucidated by spectral analysis. Bioassays showed that compound 1 had a weak antioxidant activity.
authors.affiliation: Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Materia Medica, 1 Xian Nong Tan Street, Beijing 100050, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
authors.forename: Huixin
authors.initials: H
authors.lastname: Zhu
authors.forename: Kedi
authors.initials: K
authors.lastname: Cheng
authors.forename: Zhentai
authors.initials: Z
authors.lastname: Huang
authors.forename: Yong
authors.initials: Y
authors.lastname: Qin
authors.forename: Jinling
authors.initials: J
authors.lastname: Yang
authors.forename: Ping
authors.initials: P
authors.lastname: Zhu
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001234:Aspergillus niger / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000975:Antioxidants; D002087:Butyrates