Sjogren's syndrome in a celiac patient: searching for environmental triggers.
In the last few years many studies have shown the potential role of different triggers in the pathogenesis of several autoimmune diseases. In particular, in Sjogren's syndrome the presence of a genetic background is considered determining, but environmental factors have recently been described as triggers or precipitators. In this report, we describe the case of a young woman affected by celiac disease in which an Ascaris lumbricoides infestation and estrogen therapy could have played a role in the development of Sjogren's syndrome.
D'Onofrio
F
F
Department of Internal Medicine, Catholic University, Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy.
Miele
L
L
Diaco
M
M
Santoro
L
L
De Socio
G
G
Montalto
M
M
Grieco
A
A
Gasbarrini
G
G
Manna
R
R
D000328:Adult; D000818:Animals; D001196:Ascariasis / Q000150:complications; D017164:Ascaris lumbricoides; D002446:Celiac Disease / Q000150:complications / Q000209:etiology*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D004777:Environment; D005260:Female; D006801:Humans; D012859:Sjogren's Syndrome / Q000150:complications / Q000209:etiology*
D003278:Contraceptives, Oral, Hormonal