Severe stuttering and motor tics responsive to cocaine.
Developmental stuttering and tics share many clinical and therapeutical aspects. Dopaminergic neurotransmission seems to be involved in the pathophysiology of both, tics and stuttering. We report on a patient with severe stuttering and mild facial tics which were dramatically improved by cocaine, challenging previous reports.
Linazasoro
G
G
Centro de Investigación Parkinson, Policlínica Gipuzkoa, Parque Tecnológico de Miramón, San Sebastián, Gipuzkoa, Spain. glinazasoro@terra.es
Van Blercom
N
N
D000328:Adult; D003042:Cocaine / Q000494:pharmacology*; D018491:Dopamine Agonists / Q000627:therapeutic use; D005473:Fluoxetine / Q000627:therapeutic use; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000188:drug therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D013342:Stuttering / Q000150:complications* / Q000503:physiopathology*; D020323:Tics / Q000150:complications* / Q000503:physiopathology*
D003042:Cocaine; D018491:Dopamine Agonists; D005473:Fluoxetine; D007980:Levodopa; D017367:Selective Serotonin Reuptake Inhibitors