title: [Occupational asthma caused by chromium and nickel].
abstract: We report the case of a 40-year-old woman who developed occupational asthma following exposure to chromium and nickel in the nickel-plating section of a metalworks company. Skin prick tests for specific antibodies proved positive for nickel chloride at a concentration of 1 mg/mL and negative for potassium dichromate. The specific bronchial provocation test confirmed the diagnosis of occupational asthma due to exposure to chromium and nickel. The patient presented a late positive reaction to nickel chloride (0.1 mg/mL) and an immediate positive reaction to a 10 mg/mL solution of potassium dichromate. These results indicate a dual response to nickel and chromium in this patient.
authors.affiliation: Servei de Pneumologia, Hospital Vall d'Hebron, Barcelona, España.
authors.forename: María Jesus
authors.initials: MJ
authors.lastname: Cruz
authors.forename: Roser
authors.initials: R
authors.lastname: Costa
authors.forename: Eduard
authors.initials: E
authors.lastname: Marquilles
authors.forename: Ferran
authors.initials: F
authors.lastname: Morell
authors.forename: Xavier
authors.initials: X
authors.lastname: Muñoz
mesh_terms: D000328:Adult; D001249:Asthma / Q000139:chemically induced*; D002857:Chromium / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009532:Nickel / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced*
chemical_list: D002857:Chromium; D009532:Nickel