Commercial Phaseolus vulgaris extract (starch stopper) increases ileal endogenous amino acid and crude protein losses in the growing rat.
The effect of a commercial Phaseolus vulgaris extract (PVE, starch stopper) on ileal and fecal endogenous protein losses was studied. Growing rats were fed for 14 days a protein-free diet containing PVE at a nutritional concentration of 0% (PF1), 0.4% (PF2), or 1.1% PVE (PF3) or 1.1% autoclaved PVE (PF4). An indigestible marker (TiO(2)) was included in each diet. Ileal endogenous amino acid (AA) losses were significantly higher (P < 0.05) in PF3 (20% higher than in PF1), except for Pro, Gly, Ala, and His. Endogenous ileal N losses were 22% higher in PF3 than in PF1. Endogenous fecal AA and N losses were all significantly higher (P < 0.05) in PF3. Starch digestibility ( approximately 100%), food intake (single daily meal, d10-23), and body weight loss were not significantly different among the groups. PVE, at 1.1% of the diet, not only was ineffective in reducing starch digestibility but also led to increased ileal endogenous N losses, possibly due to the antinutritional factors (trypsin inhibitor, lectin) present in the PVE.
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Institut National Agronomique Paris-Grignon, UMR INRA-INAPG 914, Physiologie de la Nutrition et du Comportement Alimentaire, 16 rue Claude Bernard, 75231 Paris Cedex 05, France. a.deglaire@massey.ac.nz
Moughan
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D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D004063:Digestion; D005243:Feces / Q000737:chemistry; D007082:Ileum / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D027805:Phaseolus / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013213:Starch / Q000378:metabolism
D000596:Amino Acids; D010936:Plant Extracts; D011506:Proteins; D013213:Starch; D009584:Nitrogen