title: Discrepancies between medication records of anticoagulation clinics and pharmacy records.
abstract: OBJECTIVE
  To determine whether there were discrepancies between with coumarin anticoagulants interacting medications recorded in medical files of anticoagulation clinics (AC-records) and computerized records of community pharmacies (pharmacy records).
  
  
  METHODS
  A descriptive study was conducted at two Dutch anticoagulation clinics (AC's). Records of with coumarin anticoagulants interacting drugs at the AC's were compared with the pharmacy records. A drug registered in the pharmacy records but not in the AC-records, was recorded as a discrepancy, while a drug registered in AC-records as well as in pharmacy records, was recorded as a match.
  
  
  RESULTS
  Of the 117 identified interacting drugs registered in pharmacy records 32 (27%) were not registered in the AC-records. In four out of seven patients of whom the use of a pharmacokinetically interacting drug was not registered in the AC-records, several INR-values exceeded the upper therapeutic range.
  
  
  CONCLUSIONS
  This study demonstrates that a substantial percentage of drugs of which an interaction with coumarin anticoagulants can be expected, is not registered in the medical files of anticoagulation clinics.
authors.affiliation: Department of Pharmacoepidemiology and Pharmacotherapy, University Institute of Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands. t.schalekamp@pharm.uu.nl
authors.forename: Tom
authors.initials: T
authors.lastname: Schalekamp
authors.forename: Carolien
authors.initials: C
authors.lastname: Smit
authors.forename: Johanna H H
authors.initials: JH
authors.lastname: van Geest-Daalderop
authors.forename: Hanneke
authors.initials: H
authors.lastname: de Vries-Goldschmeding
authors.forename: Anthonius
authors.initials: A
authors.lastname: de Boer
mesh_terms: D000368:Aged; D000554:Ambulatory Care Facilities; D000925:Anticoagulants / Q000627:therapeutic use*; D003157:Community Pharmacy Services; D004347:Drug Interactions; D016903:Drug Monitoring; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D004359:Drug Therapy, Combination; D004363:Drug Utilization / Q000706:statistics & numerical data; D006801:Humans; D019934:International Normalized Ratio; D008499:Medical Records / Q000706:statistics & numerical data*; D016347:Medical Records Systems, Computerized / Q000706:statistics & numerical data*; D008875:Middle Aged; D009426:Netherlands; D010353:Patient Education as Topic; D017891:Pharmacoepidemiology; D011446:Prospective Studies; D011785:Quality Assurance, Health Care; D012042:Registries
chemical_list: D000925:Anticoagulants