title: Venous and intrapericardial thrombosis: secondary to transient protein C deficiency.
abstract: We present a 2-month-old male infant with thrombosis in the superior vena cava and pericardium due to transient protein C deficiency. Protein C deficiency was related to sepsis and hepatitis-induced liver function impairment. The patient's cardiac anatomy was otherwise normal. The patient was referred to us with signs of superior vena cava syndrome. Pericardial mass was excised. Pathological examination diagnosed the mass as organized thrombus. After the operation, signs of superior vena cava syndrome totally resolved. Serial echocardiographic examinations revealed regression of thrombus in the superior vena cava. This is the first case reported in the literature with intrapericardial thrombus secondary to transient protein C deficiency.
authors.affiliation: Istanbul University, Cerrahpasa Medical Faculty, Koca MP/Fatih, Istanbul, Turkey. tevfikz@yahoo.com
authors.forename: Tevfik
authors.initials: T
authors.lastname: Demir
authors.forename: Tiraje
authors.initials: T
authors.lastname: Celkan
authors.forename: Gulay
authors.initials: G
authors.lastname: Ahunbay
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Babaoglu
authors.forename: Resmiye
authors.initials: R
authors.lastname: Besikci
mesh_terms: D006348:Cardiac Surgical Procedures; D004452:Echocardiography; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D010496:Pericardium / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D020151:Protein C Deficiency / Q000150:complications* / Q000175:diagnosis*; D013479:Superior Vena Cava Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013927:Thrombosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014262:Tricuspid Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery