title: N-heterocyclic carbene-catalyzed reaction of chalcones and enals via homoenolate: an efficient synthesis of 1,3,4-trisubstituted cyclopentenes.
abstract: Nucleophilic heterocyclic carbene-catalyzed cyclopentannulation of enals and chalcones via homoenolate has been observed for the first time. Serendipitously, the reaction lead to a very efficient synthesis of 3,4-trans-disubstituted-1-aryl cyclopentenes instead of the expected cyclopentanones. The strategy works well with thienylidene tetralone also, leading to the tricyclic cyclopentene derivative.
authors.affiliation: Organic Chemistry Section, Regional Research Laboratory (CSIR), Trivandrum 695 019, India. vijaynair_2001@yahoo.com
authors.forename: Vijay
authors.initials: V
authors.lastname: Nair
authors.forename: Sreekumar
authors.initials: S
authors.lastname: Vellalath
authors.forename: Manojkumar
authors.initials: M
authors.lastname: Poonoth
authors.forename: Eringathodi
authors.initials: E
authors.lastname: Suresh