title: Pd/C-catalyzed chemoselective hydrogenation in the presence of diphenylsulfide.
abstract: [Structure: see text] A Pd/C-catalyzed chemoselective hydrogenation using diphenylsulfide as a catalyst poison has been developed. This methodology selectively hydrogenates olefin and acetylene functionalities without hydrogenolysis of aromatic carbonyls and halogens, benzyl esters, and N-Cbz protective groups.
authors.affiliation: Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan.
authors.forename: Akinori
authors.initials: A
authors.lastname: Mori
authors.forename: Yumi
authors.initials: Y
authors.lastname: Miyakawa
authors.forename: Eri
authors.initials: E
authors.lastname: Ohashi
authors.forename: Tomoko
authors.initials: T
authors.lastname: Haga
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Maegawa
authors.forename: Hironao
authors.initials: H
authors.lastname: Sajiki
mesh_terms: D000114:Acetylene / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006865:Hydrogenation; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry*
chemical_list: D000475:Alkenes; D013440:Sulfides; D010165:Palladium; D000114:Acetylene