Coadsorption of guanine and cytosine on graphite: ordered structure based on GC pairing.
Nanostructures formed by coadsorption of the complementary DNA bases guanine (G) and cytosine (C) at a graphite surface in 1-octanol solvent were investigated by in situ scanning tunneling microscopy. The high-resolution observations showed for the first time a well-ordered coadsorption structure, attributed to rows formed from Watson-Crick G-C pairs, which was distinctly different from the structures observed for the individual G/C components. The observed coadsorption structure has been modeled by self-consistent charge density-functional-based tight-binding (SCC-DFTB) calculations, providing information on the intermolecular interactions underlying its formation.
Xu
Sailong
S
Interdisciplinary Nanoscience Center (iNANO) and Department of Physics and Astronomy, University of Aarhus, Denmark.
Dong
Mingdong
M
Rauls
Eva
E
Otero
Roberto
R
Linderoth
Trolle R
TR
Besenbacher
Flemming
F
D000327:Adsorption; D020029:Base Pairing; D003596:Cytosine / Q000737:chemistry*; D004247:DNA / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D006147:Guanine / Q000737:chemistry*; D016252:Microscopy, Scanning Tunneling; D049329:Nanostructures
D006147:Guanine; D006108:Graphite; D003596:Cytosine; D004247:DNA