title: Aortic root dilation secondary to giant cell aortitis in a human immunodeficiency virus-positive patient.
abstract: HIV-associated vasculitis rarely involves the aorta. There is no well-established association of HIV and giant cell arteritis. We present the case of a 31-year-old HIV positive Indian woman who was referred to us with complaints of dyspnea and chest pain. Physical examination revealed a diastolic murmur in the aortic area and echocardiography showed a dilated aortic root causing severe aortic regurgitation. She was being adequately treated with anti-HIV therapy. She underwent aortic valve and root replacement and the histopathological findings of the aortic specimen showed giant cell arteritis.
authors.affiliation: Royal Brompton Hospital, Sydney Street, London, United Kingdom.
authors.forename: Muhammad A
authors.initials: MA
authors.lastname: Javed
authors.forename: Mary N
authors.initials: MN
authors.lastname: Sheppard
authors.forename: John
authors.initials: J
authors.lastname: Pepper
mesh_terms: D000328:Adult; D001011:Aorta / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000601:surgery / Q000821:virology*; D004108:Dilatation, Pathologic / Q000821:virology; D005260:Female; D013700:Giant Cell Arteritis / Q000821:virology*; D006679:HIV Seropositivity / Q000150:complications*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans