Gold catalysis: no steric limitations in the phenol synthesis.
Different dihydroisoindol-4-ols and 8-hydroxytetrahydroisoquinolines were prepared by the gold-catalyzed phenol synthesis. The reaction was investigated with several sterically demanding groups in the 5-position of the furan starting material. The influence of the reaction time and the catalyst on the yield was investigated.
Hashmi
A Stephen K
AS
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany. hashmi@hashmi.de
Salathé
Ralph
R
Frey
Wolfgang
W