title: Two cases of malignant melanoma in turbinate and maxillary sinus.
abstract: Malignant melanomas develop from malignant transformation of melanocytes that are present in the skin and mucosal linings throughout the body. The overall rate of mucosal melanoma is rare and malignant melanomas developing from turbinates or maxillary sinuses are extremely rare. Symptoms of nasal melanoma are generally nonspecific, and patients often fail to seek prompt medical attention. Diagnosis can be confirmed by the immunochemical profile of staining with anti-S100 and HMB-45 antibodies, even in the case of melanin-free pigment melanoma. The present study reports two cases of primary malignant melanoma in the turbinate and maxillary sinus.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Inha University, Jung-Gu, Incheon 400-711, South Korea.
authors.forename: Yoon-Seok
authors.initials: YS
authors.lastname: Choi
authors.forename: Gil Soo
authors.initials: GS
authors.lastname: Han
authors.forename: Jeong-Seok
authors.initials: JS
authors.lastname: Choi
authors.forename: Tae Young
authors.initials: TY
authors.lastname: Jang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000628:therapy; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000628:therapy; D014420:Turbinates