Two cases of malignant melanoma in turbinate and maxillary sinus.
Malignant melanomas develop from malignant transformation of melanocytes that are present in the skin and mucosal linings throughout the body. The overall rate of mucosal melanoma is rare and malignant melanomas developing from turbinates or maxillary sinuses are extremely rare. Symptoms of nasal melanoma are generally nonspecific, and patients often fail to seek prompt medical attention. Diagnosis can be confirmed by the immunochemical profile of staining with anti-S100 and HMB-45 antibodies, even in the case of melanin-free pigment melanoma. The present study reports two cases of primary malignant melanoma in the turbinate and maxillary sinus.
Choi
Yoon-Seok
YS
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Inha University, Jung-Gu, Incheon 400-711, South Korea.
Han
Gil Soo
GS
Choi
Jeong-Seok
JS
Jang
Tae Young
TY
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000628:therapy; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000628:therapy; D014420:Turbinates