title: Forearm oxygen consumption and forearm blood flow in healthy children and adolescents measured by near infrared spectroscopy.
abstract: The assessment of forearm oxygen consumption (VO(2)) and forearm blood flow (FBF) by means of near infrared spectroscopy has become widespread in adults, whereas in children and adolescents no data are available. The aim of the present study was to analyze VO(2) and FBF in healthy children and adolescents.
  
  
  METHODS
  In a prospective cohort study, 20 male and 20 female healthy children and adolescents were investigated. The measurements of VO(2) and FBF were performed by means of near infrared spectroscopy in combination with the venous occlusion method.
  
  
  RESULTS
  Mean VO(2) was 0.08 +/- 0.04 ml 100 g(-1) min(-1) in male and 0.09 +/- 0.05 ml 100 g(-1) min(-1) in female subjects. Mean FBF was 1.95 +/- 1.25 ml 100 g(-1) min(-1) in male and 1.82 +/- 0.98 ml 100 g(-1) min(-1) in female subjects. No significant difference was found between male and female subjects. A significant negative correlation of VO(2) and FBF to age was observed in both groups.
  
  
  CONCLUSIONS
  In the present study we were able to show that VO(2) and FBF decreased with increasing age in children and adolescents without significant differences between male and female subjects.
authors.affiliation: Department of Paediatrics, University of Graz, Auenbruggerplatz 30, 8036 Graz, Austria. Gerhard.Pichler2@klinikum-graz.at
authors.forename: G
authors.initials: G
authors.lastname: Pichler
authors.forename: B
authors.initials: B
authors.lastname: Urlesberger
authors.forename: P
authors.initials: P
authors.lastname: Jirak
authors.forename: H
authors.initials: H
authors.lastname: Zotter
authors.forename: W
authors.initials: W
authors.lastname: Müller
mesh_terms: D000293:Adolescent; D000375:Aging / Q000502:physiology; D002648:Child; D005260:Female; D005542:Forearm / Q000098:blood supply* / Q000502:physiology*; D006801:Humans; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology*; D011446:Prospective Studies; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology; D019265:Spectroscopy, Near-Infrared