title: Repeated arterial thrombosis as a complication of carboplatin-based chemotherapy.
abstract: We describe a case of a 57-year-old woman with repeated acute arterial thrombosis of the femoral arteries following intravenous carboplatin-based combination chemotherapy for metastatic ovarian carcinoma. By extensive workup, no other known causes of arterial thrombosis were found. To our knowledge, this is the first case describing arterial thrombosis occurring as a complication of carboplatin therapy.
authors.affiliation: Department of Vascular Surgery, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Kakkhee K
authors.initials: KK
authors.lastname: Yeung
authors.forename: Erwin
authors.initials: E
authors.lastname: Coster
authors.forename: A W
authors.initials: AW
authors.lastname: Floris Vos
authors.forename: Roger K
authors.initials: RK
authors.lastname: Van der Vijgh
authors.forename: Mattheus A M
authors.initials: MA
authors.lastname: Linsen
authors.forename: Willem
authors.initials: W
authors.lastname: Wisselink
mesh_terms: D000208:Acute Disease; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D016190:Carboplatin / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy; D011859:Radiography; D012008:Recurrence; D013927:Thrombosis / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin