title: [Primary mediastinal germ cell tumors].
abstract: Primary mediastinal germ cell tumors account for approximately 10% to 20% of all neoplasms of the mediastinum. It is generally accepted that they represent the malignant transformation of germinal elements without a gonadal focus. These tumors can be classified as teratomas, seminomas, nonseminomatous (yolk sac tumor, embryonal carcinoma, choriocarcinoma) and combined germ-cell tumors without teratomatous components. This review purposes to discuss the different primary mediastinal germ-cell tumors, their clinical presentation and options for treatment.
authors.affiliation: Departamento de Cirurgia Torácica, Centro de Tratamento e Pesquisa, Hospital do Câncer A.C. Camargo, Rua Prof. Antonio Prudente 211, Liberdade, Cep. 01509-900 São Paulo/SP.
authors.forename: Wilson José
authors.initials: WJ
authors.lastname: Couto
authors.forename: Jefferson Luiz
authors.initials: JL
authors.lastname: Gross
authors.forename: Daniel
authors.initials: D
authors.lastname: Deheinzelin
authors.forename: Riad Naim
authors.initials: RN
authors.lastname: Younes
mesh_terms: D006801:Humans; D008479:Mediastinal Neoplasms / Q000145:classification / Q000473:pathology* / Q000628:therapy; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000145:classification / Q000473:pathology* / Q000628:therapy; D011379:Prognosis