title: Piperacillin-tazobactam-induced drug hypersensitivity syndrome.
abstract: The drug hypersensitivity syndrome (DHS) is a rare but serious and potentially life-threatening reaction to common drugs in predisposed individuals. The syndrome is a triad of fever, skin eruption, and internal organ involvement. Prompt identification and discontinuation of the offending drug with symptomatic treatment of toxic effects is the mainstay of therapy for DHS.
authors.affiliation: Division of Dermatology, Department of Medicine, University of Ottawa, Ontario, Canada. simonefahim@sympatico.ca
authors.forename: Simone
authors.initials: S
authors.lastname: Fahim
authors.forename: Vikas
authors.initials: V
authors.lastname: Jain
authors.forename: Gary
authors.initials: G
authors.lastname: Victor
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Pierscianowski
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000503:physiopathology*; D004502:Education, Medical, Continuing; D005260:Female; D006801:Humans; D010397:Penicillanic Acid / Q000009:adverse effects / Q000031:analogs & derivatives; D010878:Piperacillin / Q000009:adverse effects; D000077725:Piperacillin, Tazobactam Drug Combination
chemical_list: D000900:Anti-Bacterial Agents; D000077725:Piperacillin, Tazobactam Drug Combination; D010397:Penicillanic Acid; D010878:Piperacillin