title: Examination of IgM rheumatoid factor (IgM-RF) and anti-cyclic citrullinated peptide antibody (anti-CCP Ab) in Japanese patients with palindromic rheumatism.
abstract: We have studied the serology of 6 patients with palindromic rheumatism. None of the patients fulfilled the classification criteria for rheumatoid arthritis at the entry; however, 4 out of the 6 patients were seropositive for IgM rheumatoid factor (IgM-RF) at entry. Sequential serological study was performed in 4 patients; IgM-RF changed from seronegative to seropositive in one patient, and the titer increased in another patient. Anti-cyclic citrullinated peptide antibody (anti-CCP Ab) at the entry was detected in only one of the 6 patients; that patient later developed RA. Although follow-up is necessary, the present study may suggest the importance of serological examination, especially anti-CCP Ab, in patients with palindromic rheumatism.
authors.affiliation: First Department of Internal Medicine, Graduate School of Biomedical Sciences, Sakamoto, Nagasaki.
authors.forename: Mami
authors.initials: M
authors.lastname: Tamai
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawakami
authors.forename: Nozomi
authors.initials: N
authors.lastname: Iwanaga
authors.forename: Keita
authors.initials: K
authors.lastname: Fujikawa
authors.forename: Fumiko
authors.initials: F
authors.lastname: Tanaka
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Aramaki
authors.forename: Yasumori
authors.initials: Y
authors.lastname: Izumi
authors.forename: Kouichiro
authors.initials: K
authors.lastname: Aratake
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Arima
authors.forename: Makoto
authors.initials: M
authors.lastname: Kamachi
authors.forename: Hideki
authors.initials: H
authors.lastname: Nakamura
authors.forename: Mingguo
authors.initials: M
authors.lastname: Huang
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ida
authors.forename: Tomoki
authors.initials: T
authors.lastname: Origuchi
authors.forename: Katsumi
authors.initials: K
authors.lastname: Eguchi
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010456:Peptides, Cyclic / Q000097:blood / Q000276:immunology*; D012217:Rheumatoid Factor / Q000097:blood / Q000276:immunology*
chemical_list: D007075:Immunoglobulin M; D010456:Peptides, Cyclic; C487763:cyclic citrullinated peptide; D012217:Rheumatoid Factor