First total synthesis of (+/-)-3-aza-11-oxa-1,3,5(10)-trieno steroids.
We set out to describe a new and versatile method for preparing 3-aza-11-oxa-1,3,5(10)-trieno steroids via an intramolecular Diels-Alder cycloaddition of o-quinodimethanes as the key step. The characteristic 1H and 13C NMR spectroscopic features of the synthesized compounds are reported.
Oumzil
Khalid
K
UMR 6180 CNRS and Université d'Aix Marseille III: Chirotechnologies: catalyse et biocatalyse, Laboratoire de Synthèse Organique associé au CNRS, Faculté des Sciences et Techniques de Saint Jérôme, 13397 Marseille Cedex 20, France.
Ibrahim-Ouali
Malika
M
Santelli
Maurice
M
D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013256:Steroids / Q000138:chemical synthesis*
D013256:Steroids