BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments.
We present a new version of Babelomics, a complete suite of web tools for functional analysis of genome-scale experiments, with new and improved tools. New functionally relevant terms have been included such as CisRed motifs or bioentities obtained by text-mining procedures. An improved indexing has considerably speeded up several of the modules. An improved version of the FatiScan method for studying the coordinate behaviour of groups of functionally related genes is presented, along with a similar tool, the Gene Set Enrichment Analysis. Babelomics is now more oriented to test systems biology inspired hypotheses. Babelomics can be found at http://www.babelomics.org.
Al-Shahrour
Fátima
F
Bioinformatics Department, Centro de Investigación Príncipe Felipe, Autopista del Saler 16, E-46013, Valencia, Spain.
Minguez
Pablo
P
Tárraga
Joaquín
J
Montaner
David
D
Alloza
Eva
E
Vaquerizas
Juan M
JM
Conde
Lucía
L
Blaschke
Christian
C
Vera
Javier
J
Dopazo
Joaquín
J
D000818:Animals; D003196:Computer Graphics; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D005796:Genes; D023281:Genomics / Q000379:methods*; D006801:Humans; D020407:Internet; D051379:Mice; D051381:Rats; D012984:Software; D049490:Systems Biology / Q000379:methods*; D014584:User-Computer Interface