title: [Comorbidities of COPD].
abstract: Chronic obstructive pulmonary disease (COPD) is often associated with comorbidities. Cardiovascular diseases, weight loss, loss of fat free mass combined with muscle dysfunction, osteoporosis and depression are the main comorbidities in COPD. Cardiovascular comorbidities, weight loss and loss of fat free mass are predictors of mortality of patients with COPD. Thus, the extrapulmonary manifestations are meaningful parameters of clinical assessment. Systemic inflammation is probably the key to the extrapulmonary signs of COPD.
authors.affiliation: Krankenhaus Grosshansdorf, Zentrum für Pneumologie und Thoraxchirurgie und Pneumologisches Forschungsinstitut am Krankenhaus Grosshansdorf.
authors.forename: H
authors.initials: H
authors.lastname: Watz
authors.forename: H
authors.initials: H
authors.lastname: Magnussen
mesh_terms: D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D006801:Humans; D009140:Musculoskeletal Diseases / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D018384:Oxidative Stress / Q000502:physiology; D011014:Pneumonia / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects; D015996:Survival Rate; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D015431:Weight Loss / Q000502:physiology