A new method for asperphenamate synthesis and its antimicrobial activity evaluation.
Asperphenamate is a natural phenylalanine derivative. This compound was produced through a new, two-step synthetic route. It was also evaluated by the antimicrobial activity of the pure substance against Escherichia coli, Staphylococcus aureus and Cladosporium herbarum.
Pomini
Armando Mateus
AM
Universidade Estadual de Londrina - CCE - Depto. de Química, 86.051-970, Londrina PR, Brazil.
Ferreira
Dalva Trevisan
DT
Braz-Filho
Raimundo
R
Saridakis
Halha Ostrensky
HO
Schmitz
Wanderley
W
Ishikawa
Noemia Kazue
NK
Faccione
Milton
M
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002963:Cladosporium / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D019906:Nuclear Magnetic Resonance, Biomolecular; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010649:Phenylalanine; C014343:asperphenamate