title: The HUPO Brain Proteome Project--no need to hurry?
abstract: The HUPO Brain Proteome Project (HUPO BPP) is dedicated to the analysis of the brain proteome and has initiated two pilot studies in order to elaborate a standardised system for data collection and reprocessing. Samples of mouse brains (different developmental stages) and human brain tissue (biopsy and post-mortem samples) were shipped to different laboratories in Europe, Asia and the US that were invited to identify as many proteins as possible using their own approaches. In addition, a centralised data reprocessing strategy has been elaborated in an iterative way to generate highly reliable lists of identified proteins. This consortium could be a good example for a standardized proteomics workflow.
authors.affiliation: Medical Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany. michael.hamacher@rub.de
authors.forename: M
authors.initials: M
authors.lastname: Hamacher
authors.forename: K
authors.initials: K
authors.lastname: Marcus
authors.forename: A
authors.initials: A
authors.lastname: van Hall
authors.forename: H E
authors.initials: HE
authors.lastname: Meyer
authors.forename: C
authors.initials: C
authors.lastname: Stephan
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D030562:Databases, Protein; D006801:Humans; D007391:International Cooperation; D040901:Proteomics / Q000458:organization & administration*