title: Analysis of restriction fragment length polymorphism of cytochrome P450 3A43 gene and evaluation of the incidence of CYP3A43*1B allele in europeoid residents of West Siberia.
abstract: Analysis of restriction fragment length polymorphism is proposed for detecting CYP3A43 gene c1047 > T mutation. The incidence of this mutation (CYP3A43*1B allele) was evaluated in 102 europeoid residents of West Siberia and it was found to be 12.25%.
authors.affiliation: Institute of Molecular Biology and Biophysics, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk.
authors.forename: E G
authors.initials: EG
authors.lastname: Shchepotina
authors.forename: M V
authors.initials: MV
authors.lastname: Nikishina
authors.forename: V A
authors.initials: VA
authors.lastname: Vavilin
authors.forename: V V
authors.initials: VV
authors.lastname: Lyakhovich
mesh_terms: D000293:Adolescent; D000483:Alleles; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D004252:DNA Mutational Analysis; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D012800:Siberia; D044465:White People
chemical_list: D001189:Aryl Hydrocarbon Hydroxylases; C422408:CYP3A43 protein, human