title: Efficacy of physiologic temperature on the spasm of harvested radial artery.
abstract: BACKGROUND
  The potential disadvantage of using the radial artery for coronary artery bypass grafting is its increased tendency to vasospasm. Therefore, different antispastic agents are being used in the perioperative and postoperative period. During the preparation of the radial artery, normal local and systemic temperatures are lost.
  
  
  METHODS
  We investigated the effects of topical normal saline solution at 20 degrees C (group SI), normal saline solution at 36 degrees C (group SII), diltiazem at 20 degrees C (group DI), and diltiazem at 36 degrees C (group DII) on radial artery free flow. Each group contained 10 patients undergoing coronary bypass surgery. Free flow and local temperature were measured at 3 stages: after the exploration and preparation of the distal 3 cm of the radial artery, after total preparation of the radial artery, and a median of 12 minutes after the pedicle had been sprayed with one of the agents.
  
  
  RESULTS
  Parallel to the significant decrease of the second local temperatures (P < .001), the second flow of the 4 groups decreased significantly (P < .001).
  
  
  CONCLUSIONS
  Hypothermia plays an important role in radial artery vasospasm, and normothermia may be the best perioperative vasodilating agent since the normal radial artery flows were reached with normothermia.
authors.affiliation: Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.
authors.forename: Ibrahim Arif
authors.initials: IA
authors.lastname: Tarhan
authors.forename: Tamer
authors.initials: T
authors.lastname: Kehlibar
authors.forename: Fikri
authors.initials: F
authors.lastname: Yapici
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yilmaz
authors.forename: Yucesin
authors.initials: Y
authors.lastname: Arslan
authors.forename: Gultekin
authors.initials: G
authors.lastname: Saday
authors.forename: Azmi
authors.initials: A
authors.lastname: Ozler
mesh_terms: D000287:Administration, Topical; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000188:drug therapy* / Q000209:etiology; D004110:Diltiazem / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007035:Hypothermia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D017534:Radial Artery / Q000601:surgery*; D012965:Sodium Chloride / Q000008:administration & dosage; D013035:Spasm / Q000188:drug therapy* / Q000209:etiology; D013696:Temperature; D020858:Tissue and Organ Harvesting / Q000009:adverse effects*; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D014665:Vasodilator Agents; D012965:Sodium Chloride; D004110:Diltiazem