Smallpox during pregnancy and maternal outcomes.
A historical study evaluated maternal outcomes in pregnancy complicated by smallpox. The overall case fatality was estimated to be 34.3% (95% confidence interval [CI] 31.4-37.1), and the proportion of miscarriage or premature birth was estimated to be 39.9% (95% CI 36.5-43.2). Vaccination before pregnancy reduced the risk for death.
Nishiura
Hiroshi
H
Department of Medical Biometry, University of Tübingen, Tübingen, Germany. nishiura.hiroshi@uni-tuebingen.de
D000022:Abortion, Spontaneous; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D011256:Pregnancy Outcome; D047928:Premature Birth; D012899:Smallpox / Q000150:complications*