Treatment of solitary gastric carcinoid tumor by endoscopic polypectomy in a patient with pernicious anemia.
Type I gastric carcinoid tumors result from hypergastrinemia in 1%-7% of patients with pernicious anemia. We diagnosed pernicious anemia in a 48-year-old female patient with complaint of fatigue for three months. She had no gastrointestinal symptoms. Endoscopic examination ot the upper gastrointestinal tract revealed atrophic gastritis and a polypoid lesion in the corpus of 3-4 mm in size. Endoscopic polypectomy was performed. Histopathological examination of the specimen revealed positive chromogranin A and synaptophysin stainings compatible with the diagnosis of a carcinoid tumor. Serum gastrin level was increased, urinary 5-hydroxyindoleacetic acid was within the normal range. There was no other symptom, sign, or laboratory finding of a carcinoid syndrome in the patient. No metastasis was found with indium-111 octreotide scan, computed tomographies of abdomen and thorax. Type I gastric carcinoid tumors are only rarely solitary and patients with tumors < 1 cm in size may benefit from endoscopic polypectomy.
Kadikoylu
Gurhan
G
Adnan Menderes University Medical Faculty, Division of Hematology, 09100 Aydin, Turkey. gurhan@medscape.com
Yavasoglu
Irfan
I
Yukselen
Vahit
V
Ozkara
Esra
E
Bolaman
Zahit
Z
D000752:Anemia, Pernicious / Q000150:complications*; D002276:Carcinoid Tumor / Q000209:etiology / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005755:Gastrins / Q000097:blood; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000601:surgery*; D013274:Stomach Neoplasms / Q000209:etiology / Q000601:surgery*
D005755:Gastrins