title: Enhanced survival of GroESL-overproducing Lactobacillus paracasei NFBC 338 under stressful conditions induced by drying.
abstract: GroESL-overproducing Lactobacillus paracasei NFBC 338 was dried, and its viability was compared with that of controls. Spray- and freeze-dried cultures overproducing GroESL exhibited approximately 10-fold and 2-fold better survival, respectively, demonstrating the importance of GroESL in stress tolerance, which can be exploited to enhance the technological performance of sensitive probiotic cultures.
authors.affiliation: Teagasc, Moorepark Food Research Centre, Fermoy, Co. Cork, Ireland.
authors.forename: B M
authors.initials: BM
authors.lastname: Corcoran
authors.forename: R P
authors.initials: RP
authors.lastname: Ross
authors.forename: G F
authors.initials: GF
authors.lastname: Fitzgerald
authors.forename: P
authors.initials: P
authors.lastname: Dockery
authors.forename: C
authors.initials: C
authors.lastname: Stanton
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D018833:Chaperonins / Q000378:metabolism*; D015169:Colony Count, Microbial; D003470:Culture Media; D005612:Freeze Drying / Q000379:methods*; D018869:Heat-Shock Response; D007778:Lactobacillus / Q000254:growth & development* / Q000378:metabolism; D019936:Probiotics; D015854:Up-Regulation
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; C097970:GroESL protein, Bacteria; D018833:Chaperonins