title: Tuberculosis case finding and preventive therapy in an HIV voluntary counseling and testing center in Uganda.
abstract: METHODS
  A large, urban human immunodeficiency virus (HIV) voluntary counseling and testing (VCT) center in Kampala, Uganda.
  
  
  OBJECTIVE
  Tuberculosis (TB) is a leading cause of morbidity and mortality in persons with HIV infection in sub-Saharan Africa. Intensified TB case finding and use of isoniazid preventive therapy (IPT) for latent infection reduces the burden of TB, but few programs have been implemented due to concerns about feasibility.
  
  
  METHODS
  Retrospective evaluation of a TB case finding and IPT program.
  
  
  RESULTS
  Over a 25-month period, 6305 patients newly diagnosed with HIV infection underwent evaluation: 293 (5%) had TB disease; 1955 (37%) patients were not eligible for preventive therapy because they lived > 20 km away, had advanced HIV disease, or had previously had TB. Of 3366 who had a tuberculin skin test (TST) placed, 2548 (76%) had the TST read; 894 (35%) of these were positive. Of 506 persons who started treatment, 335 (66%) completed it.
  
  
  CONCLUSIONS
  This unique program was feasible, detected a high proportion of undiagnosed TB, and successfully treated persons with latent infection. Expanding access to HIV VCT as well as collaboration between HIV/ AIDS and TB programs can increase the proportion of HIV-infected persons who can benefit from these programs.
authors.affiliation: AIDS Information Center, Kampala, Uganda.
authors.forename: B
authors.initials: B
authors.lastname: Mugisha
authors.forename: N
authors.initials: N
authors.lastname: Bock
authors.forename: J
authors.initials: J
authors.lastname: Mermin
authors.forename: R M
authors.initials: RM
authors.lastname: Odeke
authors.forename: B
authors.initials: B
authors.lastname: Miller
authors.forename: F
authors.initials: F
authors.lastname: Adatu-Engwau
authors.forename: R
authors.initials: R
authors.lastname: Granich
authors.forename: R
authors.initials: R
authors.lastname: Bunnell
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003376:Counseling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control*; D014454:Uganda / Q000453:epidemiology