title: Bronchogenic carcinoma of squamous cells in a young pregnant woman.
abstract: Lung cancer continues to be the most incident neoplasia in the world and also the most frequent cause of death by cancer, with more than 900000 new cases per year. Women present greater risk of developing bronchogenic carcinoma, possibly because of differences in metabolism of the carcinogens associated with tobacco and also because of hormonal differences because estrogens can promote the appearance of lung cancer, including during pregnancy. We have described the case of a 25-year-old patient who developed squamous cell carcinoma of the lung during her third pregnancy, with a progressive worsening of her general condition and progression until death. We believe that the pregnancy could have contributed to the evolution of the disease, especially because of the increased levels of gestational hormones, particularly the estrogen, because its receptors have an important role in regulating growth and in the differentiation of several tissues facilitating like this, the development of the neoplasia, and complicating its early diagnosis.
authors.affiliation: General Pathology Division, Biological Science Department, Triângulo Mineiro Medical School, Uberaba, MG 38025-180, Brazil. 99danielsilva@bol.com.br
authors.forename: Daniel Silva Gontijo
authors.initials: DS
authors.lastname: Penha
authors.forename: Ana Karina Marques
authors.initials: AK
authors.lastname: Salge
authors.forename: Fábio
authors.initials: F
authors.lastname: Tironi
authors.forename: João Carlos
authors.initials: JC
authors.lastname: Saldanha
authors.forename: Eumenia Costa da Cunha
authors.initials: EC
authors.lastname: Castro
authors.forename: Vicente de Paula Antunes
authors.initials: Vde P
authors.lastname: Teixeira
authors.forename: Marlene Antônia
authors.initials: MA
authors.lastname: dos Reis
mesh_terms: D000328:Adult; D002283:Carcinoma, Bronchogenic / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*