Rate of progression of valvular aortic stenosis in patients undergoing dialysis.
BACKGROUND
In patients undergoing dialysis, aortic valve calcification and aortic stenosis are frequently found. However, the rate of progression of aortic stenosis is still unclear.


METHODS
In all, 55 consecutive patients undergoing dialysis were followed up by echocardiography for a period of 12 months. Patients were divided into two groups: noncalcification (no or mildly calcified aortic valve) and calcification (moderate or heavily calcified aortic valve).


RESULTS
The rate of progression of maximum aortic jet velocity and degression of aortic valve area were more rapid in calcification group than in noncalcification group (0.37 +/- 0.36 m/s and 0.17 +/- 0.29 m/s, P = .027; 0.17 +/- 0.15 cm2 and 0.04 +/- 0.07 cm2, P < .001, respectively).


CONCLUSIONS
The degree of aortic stenosis progressed more rapidly in patients undergoing dialysis with aortic valve calcification than without aortic valve calcification.
Kume
Teruyoshi
T
Department of Cardiology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan. tteru@med.kawasaki-m.ac.jp
Kawamoto
Takahiro
T
Akasaka
Takashi
T
Watanabe
Nozomi
N
Toyota
Eiji
E
Neishi
Yoji
Y
Wada
Nozomi
N
Okahashi
Noriko
N
Yoshida
Kiyoshi
K
D000368:Aged; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015984:Causality; D015897:Comorbidity; D003956:Dialysis / Q000706:statistics & numerical data*; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D017063:Outcome Assessment, Health Care / Q000379:methods; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012720:Severity of Illness Index; D014463:Ultrasonography