Favourable glycaemic effects of a new balanced liquid diet for enteral nutrition - Results of a short-term study in 30 type II diabetic patients.
A new fibre enriched (15 g/l soy polysaccharides) balanced liquid diet was developed containing 53% (of energy) as carbohydrate, 32% fat and 15% protein. 71% of carbohydrates in this formula consist of modified starch, 29% of fructose. The glycaemic response to this diabetes adapted diet (DD) was compared with an isoenergetic standard diet (SD) containing maltodextrins and sucrose and a typical continental breakfast (CB). 30 type II diabetics orally ingested isoenergetic amounts of these test diets in randomised order. Each diet contained 48 g carbohydrates. The 4 h postprandial (p.p.) observation period was characterised by a markedly improved response of blood glucose following ingestion of DD. This effect was seen as significantly reduced p.p. peaks (p < 0.00001 vs SD; p = 0.00001 vs CB) as well as diminished areas under the curve. (p < 0.00001 vs SD; p = 0.00001 vs CB). Similar results were obtained by evaluation of the corresponding insulin levels. The differences between the test diets were greater in insulin treated patients than in diabetics on sulfonylureas or a dietary regimen only. We conclude that this new balanced liquid diet can be helpful in maintaining a good glycaemic control in diabetics receiving artificial enteral nutrition and may be administered in a similar way to normal foods without changes in the patients antidiabetic therapy.
Stürmer
W
W
Department of Internal Medicine, University of Würzburg, Germany.
Kramer
E
E
Kasper
H
H
Schrezenmeir
J
J