Melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity.
Handlon
Anthony L
AL
Metabolic and Viral Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398, USA. tony.l.handlon@gsk.com
Zhou
Huiqiang
H
D000818:Animals; D019440:Anti-Obesity Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D004734:Energy Metabolism; D006801:Humans; D007028:Hypothalamic Hormones / Q000502:physiology; D020738:Leptin / Q000502:physiology; D008543:Melanins / Q000502:physiology; D009765:Obesity / Q000188:drug therapy* / Q000378:metabolism; D010907:Pituitary Hormones / Q000502:physiology; D017481:Receptors, Somatostatin / Q000037:antagonists & inhibitors*
D019440:Anti-Obesity Agents; D007028:Hypothalamic Hormones; D020738:Leptin; C103263:MCHR1 protein, human; C491208:MCHR1 protein, rat; D008543:Melanins; D010907:Pituitary Hormones; D017481:Receptors, Somatostatin; C019463:melanin-concentrating hormone