title: [Prevalence of metabolic syndrome in the adult population of Yecla (Murcia). Degree of agreement between three definitions of it].
abstract: OBJECTIVE
  To determine the prevalence of metabolic syndrome (MS), its components and insulin resistance (IR) in the adult population of Yecla. To study the variability between 3 definitions of the syndrome and IR. To identify the variables that predict the presence of IR and to verify the diagnostic validity of several strategies for predicting it.
  
  
  METHODS
  Descriptive, cross-sectional study.
  
  
  METHODS
  Primary care, Yecla (Murcia), Spain.
  
  
  METHODS
  We studied 317 persons (292 with analysis) out of 424 selected by stratified (age and sex) random sampling from 18,059 people > or = 30 years old and possessing a health card.
  
  
  METHODS
  We used WHO-98, NCEP III, and EGIR criteria for diagnosing MS, and WHO-99 for defining DM2, impaired basal glucose and impaired glucose tolerance. The following variables were collected: social, demographic and personal details, plasma lipid, glycosylated haemoglobin, microalbuminuria, and insulin levels. IR was defined by the HOMA method at > or = 3.8 or as the highest quartile of basal insulinemia in normoglycaemic persons.
  
  
  RESULTS
  MS prevalence was NCEP 20.2% (95% CI, 15.6-24.8), WHO 35.3% (95% CI, 29.8-40.8), EGIR 24% (95% CI, 19.1-28.9), and IR was 27.7% (95% CI, 22.6-32.8). The sensitivity and specificity of NCEP, WHO, and EGIR criteria for detecting IR were (46% and 90%), (78% and 81%), and (73% and 95%), respectively. Insulin resistance was associated significantly with age, basal glycaemia, triglycerides, and waist circumference.
  
  
  CONCLUSIONS
  Metabolic syndrome is common in Yecla (more so in men). There is disagreement between several diagnostic criteria for the syndrome, with NCEP criteria less sensitive in determining IR. A generally accepted definition is needed.
authors.affiliation: Centro Salud Mariano Yago, Grupo de Estudio Diabetes en AP (Red-GEDAPS), Yecla, Murcia, España. jmartinezc@inicia.es
authors.forename: Juan
authors.initials: J
authors.lastname: Martínez Candela
authors.forename: Josep
authors.initials: J
authors.lastname: Franch Nadal
authors.forename: Josefa
authors.initials: J
authors.lastname: Romero Ortiz
authors.forename: Carmen
authors.initials: C
authors.lastname: Cánovas Domínguez
authors.forename: Arístides
authors.initials: A
authors.lastname: Gallardo Martín
authors.forename: Miguel
authors.initials: M
authors.lastname: Páez Pérez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003627:Data Interpretation, Statistical; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D012372:ROC Curve; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology; D014944:World Health Organization
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin