Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance.
Brief, intense exercise training may induce metabolic and performance adaptations comparable to traditional endurance training. However, no study has directly compared these diverse training strategies in a standardized manner. We therefore examined changes in exercise capacity and molecular and cellular adaptations in skeletal muscle after low volume sprint-interval training (SIT) and high volume endurance training (ET). Sixteen active men (21 +/- 1 years, ) were assigned to a SIT or ET group (n = 8 each) and performed six training sessions over 14 days. Each session consisted of either four to six repeats of 30 s 'all out' cycling at approximately 250% with 4 min recovery (SIT) or 90-120 min continuous cycling at approximately 65% (ET). Training time commitment over 2 weeks was approximately 2.5 h for SIT and approximately 10.5 h for ET, and total training volume was approximately 90% lower for SIT versus ET ( approximately 630 versus approximately 6500 kJ). Training decreased the time required to complete 50 and 750 kJ cycling time trials, with no difference between groups (main effects, P </= 0.05). Biopsy samples obtained before and after training revealed similar increases in muscle oxidative capacity, as reflected by the maximal activity of cytochrome c oxidase (COX) and COX subunits II and IV protein content (main effects, P </= 0.05), but COX II and IV mRNAs were unchanged. Training-induced increases in muscle buffering capacity and glycogen content were also similar between groups (main effects, P </= 0.05). Given the large difference in training volume, these data demonstrate that SIT is a time-efficient strategy to induce rapid adaptations in skeletal muscle and exercise performance that are comparable to ET in young active men.
Gibala
Martin J
MJ
Department of Kinesiology IWC AB122, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada. gibalam@mcmaster.ca
Little
Jonathan P
JP
van Essen
Martin
M
Wilkin
Geoffrey P
GP
Burgomaster
Kirsten A
KA
Safdar
Adeel
A
Raha
Sandeep
S
Tarnopolsky
Mark A
MA
D000222:Adaptation, Physiological; D000328:Adult; D003576:Electron Transport Complex IV / Q000378:metabolism; D004734:Energy Metabolism; D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance; D006003:Glycogen / Q000378:metabolism; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism / Q000502:physiology*; D010806:Physical Education and Training / Q000379:methods; D010807:Physical Endurance / Q000502:physiology*; D013997:Time Factors
D006003:Glycogen; D003576:Electron Transport Complex IV