title: Hospital-acquired Bordetella bronchiseptica infection following hematopoietic stem cell transplantation.
abstract: Two patients who had undergone nonmyeloablative allogeneic stem cell transplantation 53 and 112 days earlier and were being monitored at the same transplant center developed severe Bordetella bronchiseptica infections within 3 days of each other. Pulsed-field gel electrophoresis analysis indicated that the isolates from the two cases were identical. Neither patient had had direct contact with animals since transplantation. These findings strongly support nosocomial transmission of B. bronchiseptica.
authors.affiliation: Department of Medicine, Vanderbilt University Hospital, Medical Center, 4605 TVC, Nashville, TN 37232-5310, USA.
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Huebner
authors.forename: Brian
authors.initials: B
authors.lastname: Christman
authors.forename: Stephen
authors.initials: S
authors.lastname: Dummer
authors.forename: Yi-Wei
authors.initials: YW
authors.lastname: Tang
authors.forename: Stacey
authors.initials: S
authors.lastname: Goodman
mesh_terms: D001885:Bordetella Infections / Q000382:microbiology / Q000635:transmission*; D016950:Bordetella bronchiseptica / Q000145:classification / Q000302:isolation & purification*; D003428:Cross Infection / Q000382:microbiology / Q000635:transmission*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D018380:Hematopoietic Stem Cell Transplantation; D006689:Hodgkin Disease / Q000150:complications / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D009101:Multiple Myeloma / Q000150:complications / Q000628:therapy
chemical_list: D004269:DNA, Bacterial