Effect of therapy with atypical antipsychotic drugs on prolactin concentration in patients with schizophrenia and schizoaffective disorders.
Plasma prolactin concentration was measured in patients with schizophrenia and schizoaffective disorders receiving therapy with risperidone, olanzapine, and quetiapine and compared with the corresponding parameter in patient receiving typical neuroleptic drug haloperidol. We evaluated the specific effects of the test drugs on prolactin concentration in men and women.
Gorobets
L N
LN
Department of Psychiatric Endocrinology, Moscow Institute of Psychiatry, Federal Agency of Public Health and Social Development. lav@nm.ru
D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000494:pharmacology; D003987:Dibenzothiazepines / Q000494:pharmacology; D005260:Female; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D011388:Prolactin / Q000097:blood*; D011618:Psychotic Disorders / Q000188:drug therapy*; D000069348:Quetiapine Fumarate; D018967:Risperidone / Q000494:pharmacology; D012559:Schizophrenia / Q000188:drug therapy*; D012737:Sex Factors
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D001569:Benzodiazepines; D000069348:Quetiapine Fumarate; D011388:Prolactin; D006220:Haloperidol; D018967:Risperidone; D000077152:Olanzapine