title: A prospective comparison of central and peripheral vein access for parenteral nutrition in the newborn.
abstract: Central venous parenteral nutrition (PN) is frequently used in preterm infants. Although central venous catheters (CVC) permit reliable delivery of hypertonic solution, they may be associated with more serious complications than when a peripheral venous infusion is used. The aim of this randomised prospective study was to compare complications of central versus peripheral venous access using Silastic catheters identical expect for intravascular length. Eighty such devices were inserted, 38 central (CVC), 42 peripheral (PVC). Catheter life was not significantly different between groups: median (range) CVC 10d (2-25); PVC 7d (1-22) with no difference in overall complication rate. Although peripherally sited catheters tended not to function for as long as CVCs, they offer a useful alternative to central venous catheterisation.
authors.affiliation: Peter Congdon Neonatal Unit, Clarendon Wing, The General Infirmary at Leeds, Belmont Grove, Leeds LS2 9NS, UK.
authors.forename: A M
authors.initials: AM
authors.lastname: Childs
authors.forename: D G
authors.initials: DG
authors.lastname: Murdoch Eaton
authors.forename: P
authors.initials: P
authors.lastname: Standring
authors.forename: J W
authors.initials: JW
authors.lastname: Puntis