title: [Study on the structure activity relationship of a phytosiderophore, mugineic acid].
abstract: To study the structure-activity relationship of mugineic acid (MA), a phytosiderophore isolated from Hordeum velugare L. var. Minorimugi, several 2-deoxymugineic acid (DMA) analogues were synthesized. 1H-NMR spectra of DMA analogues and their Co(III) complexes were first measured and analyzed to elucidate the structures of metal complexes. CD spectra of the Co(III) and Fe(III) complexes of DMA analogues were then measured and compared with those of MA. Furthermore, the interaction between the Fe(III) complexes of DMA analogues and the phytosiderophore-Fe(III) complex transporter found in maize was examined.
authors.affiliation: Faculty of Science and Technology, Kinki University, Kowakae, Higashi-osaka City, Japan. nishimalu@mail.goo.ne.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nishimaru
mesh_terms: D001383:Azetidinecarboxylic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003035:Cobalt; D005290:Ferric Compounds / Q000378:metabolism; D001467:Hordeum / Q000737:chemistry; D026901:Membrane Transport Proteins; D019906:Nuclear Magnetic Resonance, Biomolecular; D017262:Siderophores; D013329:Structure-Activity Relationship; D003313:Zea mays
chemical_list: D005290:Ferric Compounds; D026901:Membrane Transport Proteins; D017262:Siderophores; D003035:Cobalt; D001383:Azetidinecarboxylic Acid; C052864:2'-deoxymugineic acid; C052863:mugineic acid