title: Enantioselective synthesis of (2R,3R)- and (2S,3S)-2- [(3-chlorophenyl)-(2-methoxyphenoxy)methyl]morpholine.
abstract: The enantioselective synthesis of the (R,R)- and (S,S)-enantiomers of 1 from commercially available 3-chlorocinnamic acid is reported. The Sharpless asymmetric epoxidation was used to establish the stereocenters in the synthesis of both enantiomers of 1.
authors.forename: Wayne W
authors.initials: WW
authors.lastname: Harding
authors.forename: Matthis
authors.initials: M
authors.lastname: Hodge
authors.forename: Zhixia
authors.initials: Z
authors.lastname: Wang
authors.forename: William L
authors.initials: WL
authors.lastname: Woolverton
authors.forename: Damon
authors.initials: D
authors.lastname: Parrish
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Deschamps
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Prisinzano