Middle ear adenoma.
Middle ear adenoma is a benign tumor of the middle ear that can have exocrine (mucinous) and/or neuroendocrine differentiation. Early authors described a separate tumor with predominantly neuroendocrine differentiation as a middle ear carcinoid tumor, but these are now known to be the same tumor. We review the literature of this tumor, including the clinical presentation, gross pathology, histopathology, immunohistochemistry, differential diagnosis, and prognosis.
Berns
Stephen
S
Orlando Regional Healthcare System Department of Pathology/M. D. Anderson Cancer Center, Orlando, Florida 32806, USA. stephenmberns@hotmail.com
Pearl
Gary
G
D000236:Adenoma / Q000737:chemistry / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D004428:Ear Neoplasms / Q000737:chemistry / Q000473:pathology*; D004432:Ear, Middle; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D009442:Neurilemmoma / Q000175:diagnosis; D010212:Papilloma / Q000175:diagnosis; D010235:Paraganglioma / Q000175:diagnosis; D011379:Prognosis
D014408:Biomarkers, Tumor