title: Adherence to latent tuberculosis infection therapy among latino immigrants.
abstract: BACKGROUND
  One third of the world population is infected with Mycobacterium tuberculosis. In the United States, a key component for eliminating tuberculosis (TB) is treating latent TB infection (LTBI) in high-risk persons such as immigrants.
  
  
  OBJECTIVE
  Examine the prevalence of adherence to LTBI therapy and the influence of basic conditioning factors on adherence among Latino immigrants, guided by Orem's Self-Care Deficit Theory. Adherence was treated as a health deviation self-care requisite; the self-care practice of taking daily medication for 9 months is essential to LTBI adherence. Conditioning factors include gender, age, sociocultural factors, environment, and health state.
  
  
  METHODS
  Exploratory, cross-sectional.
  
  
  METHODS
  Nonprobability sample (n=53) of Latino immigrants attending an urban public health clinic in the Washington, DC metropolitan area.
  
  
  METHODS
  Participants completed a brief questionnaire documenting selected conditioning factors, and 9-month adherence to LTBI therapy was determined from their medical records.
  
  
  RESULTS
  Adherence dropped from 98% in month 2 to 72% at 9 months. The mean number of months adherent was 7.4. Adherence was not significantly associated with gender, country of origin, languages spoken, age, education, or years in the United States. Adherence was slightly lower (t=2.059, p=.059) in persons who knew someone with TB.
  
  
  CONCLUSIONS
  Nurses should emphasize the importance of adherence for the full 9 months to this population.
authors.affiliation: College of Nursing and Health Science, George Mason University, Fairfax, Virginia 22030, USA. failinge@gmu.edu
authors.forename: Rita L
authors.initials: RL
authors.lastname: Ailinger
authors.forename: Jean B
authors.initials: JB
authors.lastname: Moore
authors.forename: Nga
authors.initials: N
authors.lastname: Nguyen
authors.forename: Howard
authors.initials: H
authors.lastname: Lasus
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004219:District of Columbia; D004641:Emigration and Immigration; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D007843:Latin America / Q000208:ethnology; D008297:Male; D010349:Patient Compliance; D012648:Self Care; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents