Repeated subileus due to angioedema during renin-angiotensin system blockade.
A 77-year-old man with membranous nephropathy was treated with triple blockade of the renin-angiotensin-aldosterone system and developed subileus six times in 5 months. The resection of his sigmoid colon uncovered angioedema. It should be noted that angiotensin-converting enzyme or angiotensin receptor blocker can cause angioedema of the intestine and induce subileus.
Tojo
Akihiro
A
Division of Nephrology and Endocrinology, University of Tokyo, Tokyo, Japan. tojyo-2im@h.u-tokyo.ac.jp
Onozato
Maristela Lika
ML
Fujita
Toshiro
T
D000368:Aged; D000799:Angioedema / Q000150:complications* / Q000473:pathology; D047228:Angiotensin II Type 1 Receptor Blockers / Q000009:adverse effects*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D012809:Colon, Sigmoid / Q000473:pathology; D015433:Glomerulonephritis, Membranous / Q000188:drug therapy; D006801:Humans; D045823:Ileus / Q000209:etiology* / Q000473:pathology; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists / Q000009:adverse effects*; D012008:Recurrence; D012084:Renin-Angiotensin System / Q000187:drug effects*
D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D000451:Mineralocorticoid Receptor Antagonists