title: [Progress in the study of gene duplication].
abstract: Gene duplication is one of the most important factors that influence the evolution of genome size, the origination of novel gene, the genetic robustness against null mutations, the speciation, etc. Duplication can be created by unequal crossing over, retroposition, or whole genome (or chromosomal) duplication. In this review, we summarized the studies of the molecular mechanisms of gene duplication, the preservation of duplicated gene, the selections acting on duplicated gene, the alternative ways of divergence and the evolution rate.
authors.affiliation: State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, China. gattacaPGZ@hotmail.com
authors.forename: Gui-Zi
authors.initials: GZ
authors.lastname: Peng
authors.forename: Ling-Ling
authors.initials: LL
authors.lastname: Chen
authors.forename: Da-Cheng
authors.initials: DC
authors.lastname: Tian
mesh_terms: D000818:Animals; D003434:Crossing Over, Genetic; D019143:Evolution, Molecular; D020440:Gene Duplication; D042822:Genomic Instability; D006801:Humans; D008957:Models, Genetic