title: Central retinal artery occlusion: findings in optical coherence tomography and functional correlations.
abstract: BACKGROUND
  Visual prognosis in central retinal artery occlusion (CRAO) is poor and not predictable in individual patients. There may be a correlation between visual acuity and extent of initial macular edema.
  
  
  METHODS
  Central retinal thickness of eleven patients with subtotal CRAO was measured with optical coherence tomography (OCT). Patients' acute-stage macular thicknesses were compared to those of later stages. Values are given as mean (+/-standard error; range).
  
  
  RESULTS
  The mean age of the eleven patients was 68.8 years (62-75). Eight men and three women were examined. The mean initial duration of CRAO was 24.7 (+/- 5.0; 4-77) hours. Initial central thickness was 372.5 (+/- 27.1; 258-522) microm. After 5.7 (+/- 1.5; 1-17) months, mean reduction in macular edema was 197 (+/- 31.3; 63-391) microm. Visual acuity (VA) improved from 0.0125 (+/- 0.2; blindness -0.6) to 0.035 (+/- 0.2; blindness - 0.8) namely 4.5 lines. This difference was significant (p= 0.023). 6/11 patients (55 %) initially had a pronounced central retinal edema (>380 microm). No correlation was found between the initial macular edema height and visual improvement.
  
  
  CONCLUSIONS
  The extent of macular edema differs widely and does not affect visual prognosis in CRAO eyes.
authors.affiliation: University Eye Hospital, D-79106 Freiburg, Germany. Dieter.Schmidt@uniklinik-freiburg.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Schmidt
authors.forename: T
authors.initials: T
authors.lastname: Kube
authors.forename: N
authors.initials: N
authors.lastname: Feltgen
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012161:Retinal Artery / Q000473:pathology*; D015356:Retinal Artery Occlusion / Q000175:diagnosis*; D041623:Tomography, Optical Coherence