Design and stability of a novel coiled-coil peptide.
According to a template of natural protein, a novel peptide was designed with satisfied stability which came from the formation of coiled-coil dimer in vitro. The knowledge gained from this study is not only useful in antiparallel coiled-coil designing but also provide an ideal antiparallel coiled-coil model in future research.
Wei
Xiang
X
Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.
Zeng
Xian-Gang
XG
Zhou
Hai-Meng
HM
D000595:Amino Acid Sequence; D002942:Circular Dichroism; D019281:Dimerization; D019791:Guanidine / Q000737:chemistry; D008956:Models, Chemical; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry*; D017434:Protein Structure, Tertiary; D013696:Temperature
C518065:ARAC peptide; D010455:Peptides; D019791:Guanidine