Short communication: antimicrobial drug susceptibility of Staphylococcus aureus from subclinical bovine mastitis in Italy.
The antimicrobial susceptibility of 68 Staphylococcus aureus isolates collected during 2004 from milk of cows affected by subclinical mastitis was examined. The antimicrobial agents tested were the beta-lactams, penicillin G, amoxicillin, ampicillin, cloxacillin, amoxicillin + clavulanate, cephalonium, and cefoperazone; and other drugs including lincomycin, oxytetracycline, doxycycline, and kanamycin. Minimum inhibitory concentrations recorded show that only certain beta-lactamase-resistant penicillins (specifically cloxacillin) or penicillin combinations (amoxicillin + clavulanate) were consistently effective against Staph. aureus, whereas the other beta-lactam derivatives and drugs from other pharmacological groups were either moderately effective or ineffective. Thus, beta-lactamase-resistant penicillins are to be considered the antimicrobial agents of choice for treatment of bovine mastitis resulting from infection by Staph. aureus.
Moroni
P
P
Department of Veterinary Pathology, Hygiene and Public Health, University of Milan, via Celoria 10, 20133 Milan, Italy. paolo.moroni@unimi.it
Pisoni
G
G
Antonini
M
M
Villa
R
R
Boettcher
P
P
Carli
S
S
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001426:Bacterial Proteins / Q000187:drug effects*; D002417:Cattle; D002511:Cephalosporins / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D005260:Female; D007558:Italy; D055231:Lincosamides; D018942:Macrolides / Q000008:administration & dosage; D008414:Mastitis, Bovine / Q000188:drug therapy / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000008:administration & dosage; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000187:drug effects*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000662:veterinary
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002511:Cephalosporins; D055231:Lincosamides; D018942:Macrolides; D010406:Penicillins; D002981:Clindamycin; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; C030182:phosphocarrier protein HPr