title: Evaluation of the hypolipemic property of Camellia sinensisVar. ptilophylla on postprandial hypertriglyceridemia.
abstract: A naturally decaffeinated tea, Camellia sinensis var. ptilophylla (cocoa tea), has long been popular in southern China as a healthy beverage. Our experiments indicate that a single oral administration of 500 mg/kg of cocoa tea extract suppresses increases in plasma triacylgycerol (TG) levels when fed with 5 mL/kg of olive or lard oil in mice and that the inhibition rates are 22.9% and 31.5%, respectively, compared with controls. Under the same condition, cocoa tea extract did not affect the level of plasma free fatty acid. Likewise, the extract reduced the lymphatic absorption of lipids at 250 and 500 mg/kg. Also, cocoa tea extract and polyphenols isolated from cocoa tea inhibit pancreatic lipase. These findings suggest that cocoa tea has hypolipemic activity, which may be due to the suppression of digestive lipase activity by the polyphenols contained within the tea.
authors.affiliation: Institute of Traditional Chinese Medicine and Natural Products, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kurihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shibata
authors.forename: Yuko
authors.initials: Y
authors.lastname: Fukui
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Kiso
authors.forename: Jie-Kun
authors.initials: JK
authors.lastname: Xu
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Yao
authors.forename: Harukazu
authors.initials: H
authors.lastname: Fukami
mesh_terms: D000818:Animals; D028241:Camellia sinensis / Q000737:chemistry*; D002392:Catechin / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D004041:Dietary Fats; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D005502:Food; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D008049:Lipase / Q000037:antagonists & inhibitors; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D000069463:Olive Oil; D010636:Phenols / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D010938:Plant Oils / Q000008:administration & dosage; D059808:Polyphenols; D014280:Triglycerides / Q000097:blood
chemical_list: D004041:Dietary Fats; D004791:Enzyme Inhibitors; D005230:Fatty Acids, Nonesterified; D005419:Flavonoids; D000960:Hypolipidemic Agents; D000069463:Olive Oil; D010636:Phenols; D010936:Plant Extracts; D010938:Plant Oils; D059808:Polyphenols; D014280:Triglycerides; D002392:Catechin; D008049:Lipase; C029310:lard