title: [Subdural empyema in children: therapeutic strategy. Five cases].
abstract: We report a series of five subdural empyema (SDE) in children and young adults treated in the same neurosurgical department. These five cases were reviewed retrospectively. There were four boys and one girl, aged from three months to 18 years at time of diagnosis (median age: 7 years). SDE following intracranial surgery were excluded from the study. All patients were treated surgically (burr hole evacuation or craniotomy, repeated in some cases), followed by intravenous antibiotic therapy (mean time: 52 days) adapted to the micro-organism. Only the two patients treated by large craniotomy at first had a single surgical procedure. Involved micro-organisms are as follow: Streptococcus intermedius (n=2), Streptococcus pneumoniae (n=1), Escherichia coli (n=1), absence of any identified micro-organism (n=1). The five patients are alive (median follow-up: 22 month) without any sequelae. We advocate an aggressive surgical treatment of SDE in children with a large bone flap to allow the surgeon to remove pus and membranes as much as possible, even in the interhemispheric fissure, followed by intravenous appropriate antibiotherapy and eradication of the source of infection. Even this "aggressive" treatment may sometimes not avoid re-operation. A careful follow-up is mandatory, because of the high risk of recurrence.
authors.affiliation: Département de Neurochirurgie, Hôpital Central, CHU, 29, avenue Maréchal-de-Lattre-de-Tassigny, 54035 Nancy Cedex. o.klein@chu-nancy.fr
authors.forename: O
authors.initials: O
authors.lastname: Klein
authors.forename: S
authors.initials: S
authors.lastname: Freppel
authors.forename: H
authors.initials: H
authors.lastname: Schuhmacher
authors.forename: C
authors.initials: C
authors.lastname: Pinelli
authors.forename: J
authors.initials: J
authors.lastname: Auque
authors.forename: J-C
authors.initials: JC
authors.lastname: Marchal
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003399:Craniotomy; D013354:Empyema, Subdural / Q000601:surgery / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D019635:Neurosurgical Procedures; D011183:Postoperative Complications / Q000188:drug therapy; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents