title: Human development I: twenty fundamental problems of biology, medicine, and neuro-psychology related to biological information.
abstract: In a new series of papers, we address a number of unsolved problems in biology today. First of all, the unsolved enigma concerning how the differentiation from a single zygote to an adult individual happens has been object for severe research for decades. By uncovering a new holistic biological paradigm that introduces an energetic-informational interpretation of reality as a new way to experience biology, these papers will try to solve the problems connected with the events of biological ontogenesis involving a fractal hierarchy, from a single cell to the function of the human brain. The problems discussed are interpreted within the frames of a universe of roomy fractal structures containing energetic patterns that are able to deliver biological information. We think biological organization is guided by energetic changes on the level of quantum mechanics, interacting with the intention that again guides the energetic conformation of the fractal structures to gain disorders or healthiness. Furthermore, we introduce two new concepts: "metamorphous top down" evolution and "adult human metamorphosis". The first is a new evolutionary theory involving metamorphosis as a main concept of evolution. The last is tightly linked to the evolutionary principle and explains how human self-recovery is governed. Other subjects of special interest that we shall look deeper into are the immunological self-nonself discrimination, the structure and function of the human brain, the etiology and salutogenesis of mental and somatic diseases, and the structure of the consciousness of a human being. We shall criticize Szentagothai's model for the modulated structure of the human cerebral cortex and Jerne's theory of the immunological regulatory anti-idiotypic network.
authors.affiliation: Quality of Life Research Center, Teglgårdstraede 4-8, DK-1452 Copenhagen K, Denmark.
authors.forename: Tyge Dahl
authors.initials: TD
authors.lastname: Hermansen
authors.forename: Søren
authors.initials: S
authors.lastname: Ventegodt
authors.forename: Erik
authors.initials: E
authors.lastname: Rald
authors.forename: Birgitte
authors.initials: B
authors.lastname: Clausen
authors.forename: Maj Lyck
authors.initials: ML
authors.lastname: Nielsen
authors.forename: Joav
authors.initials: J
authors.lastname: Merrick
mesh_terms: D001695:Biology; D006694:Holistic Health; D006803:Human Development; D006801:Humans; D008511:Medicine; D009484:Neuropsychology