title: metaSHARK: a WWW platform for interactive exploration of metabolic networks.
abstract: The metaSHARK (metabolic search and reconstruction kit) web server offers users an intuitive, fully interactive way to explore the KEGG metabolic network via a WWW browser. Metabolic reconstruction information for specific organisms, produced by our automated SHARKhunt tool or from other programs or genome annotations, may be uploaded to the website and overlaid on the generic network. Additional data from gene expression experiments can also be incorporated, allowing the visualization of differential gene expression in the context of the predicted metabolic network. metaSHARK is available at http://bioinformatics.leeds.ac.uk/shark/.
authors.affiliation: Faculty of Biological Sciences, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK.
authors.forename: Christopher
authors.initials: C
authors.lastname: Hyland
authors.forename: John W
authors.initials: JW
authors.lastname: Pinney
authors.forename: Glenn A
authors.initials: GA
authors.lastname: McConkey
authors.forename: David R
authors.initials: DR
authors.lastname: Westhead
mesh_terms: D000818:Animals; D003196:Computer Graphics; D020869:Gene Expression Profiling; D020407:Internet; D008660:Metabolism / Q000235:genetics; D008954:Models, Biological; D012984:Software; D014584:User-Computer Interface