title: Characterization of bovine tau-preparations by two-dimensional gel electrophoresis.
abstract: The molecular diversity of bovine tau obtained by three different preparation protocols was characterized by immunoblot analyses after two-dimensional gel electrophoresis. These analyses revealed that tau was heterogeneously modified, that is, up to 20 spots separated along the pH gradient, mostly independent of the preparation protocol.
authors.affiliation: Bioanalytics, Center for Biotechnology and Biomedicine, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.
authors.forename: Daniela
authors.initials: D
authors.lastname: Volke
authors.forename: Ralf
authors.initials: R
authors.lastname: Hoffmann
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D004591:Electrophoresis, Polyacrylamide Gel; D015151:Immunoblotting; D016875:tau Proteins / Q000737:chemistry*
chemical_list: D016875:tau Proteins