[Detection of the metabolite of delta-9-tetrahydrocannabinol in urine by means of GC/MS and interpretation of analytical findings].
Delta-9-tetrahydrocannabinol is one of many components of plants of Cannabis. In the human body it is susceptible to oxidation and its metabolites together with metabolites of other cannabinoids are excreted into urine and faeces. In this paper there is described our experience with the specific confirmation of the metabolite of the main psychoactive substance, 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid, using gas chromatography with mass spectrometry after urine alkaline hydrolisis, solid phase extraction and silylation. The preliminary immunochemical screening of cannabinoids in urine is performed by EMIT method.
Balíková
M
M
Ustav pro toxikologii a soudní chemii 1. LF UK a VFN, Praha.
Maresová
V
V
D013759:Dronabinol / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D002189:Marijuana Abuse / Q000175:diagnosis*; D011619:Psychotropic Drugs / Q000652:urine
D011619:Psychotropic Drugs; D013759:Dronabinol