Chemical studies on the constituents of the chinese medicinal herb Euphorbia helioscopia L.
Euphoheliosnoid D (1), a new jatrophone-type diterpenoid, was isolated together with 22 known metabolites from the Chinese medicinal herb Euphorbia helioscopia L. The structure and relative stereochemistry of 1 was elucidated on the basis of spectroscopic methods. Compounds 14-23 were obtained from the species for the first time while compound 14, 2alpha-hydroxy helioscopinolide B, was isolated as a new natural product.
Zhang
Wen
W
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Zu Chong Zhi Rd. 555, Zhangjiang Hi-Tech park, Shanghai 201203, PR China.
Guo
Yue-Wei
YW
D004224:Diterpenes / Q000032:analysis* / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D028481:Euphorbia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C513806:euphoheliosnoid D