Photochemical route to the synthesis of thiolane 1-oxides.
The preparation of thiolane 1-oxide 10 by photochemically mediated rearrangement of sulfoxide 9 in high yield is described. The efficient construction of quaternary carbon centers underscores the utility of this methodology in organic synthesis. Further manipulation of photoadduct 10 leads to the formation of diverse heterocyclic structures.
Winkler
Jeffrey D
JD
Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. winkler@sas.upenn.edu
Lee
Esther C Y
EC
D015394:Molecular Structure; D010777:Photochemistry / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis*
D013438:Sulfhydryl Compounds