Neurogenesis in diseases of the central nervous system.
Neurogenesis is altered in ageing, and diseases of the central nervous system (CNS) such as neurodegenerative disorders. We discuss the process of neurogenesis, its relevance for disorders of the CNS, the dynamic nature of neurogenesis, how and why it may be abnormal in ageing, and disease, and possibilities to ameliorate abnormal neurogenesis in disease.
Phillips
Wendy
W
Cambridge Centre for Brain Repair, UK.
Michell
Andrew W
AW
Barker
Roger A
RA
D000375:Aging / Q000473:pathology; D000818:Animals; D002454:Cell Differentiation; D002490:Central Nervous System / Q000166:cytology / Q000473:pathology*; D003863:Depression / Q000473:pathology; D006801:Humans; D009422:Nervous System Diseases / Q000473:pathology*; D009474:Neurons / Q000166:cytology / Q000473:pathology*