title: Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression.
abstract: The authors examined 179 veterans with chronic obstructive pulmonary disease (COPD) to determine the relative contribution of clinical depression and/or anxiety (Beck Depression and Beck Anxiety Inventories) to their quality of life (Chronic Respiratory Questionnaire and Medical Outcomes Survey Short Form). Multiple-regression procedures found that both depression and anxiety were significantly related to negative quality-of-life outcomes (anxiety with both mental and physical health quality-of-life outcomes, and depression primarily with mental health). When comorbid with COPD, mental health symptoms of depression and anxiety are some of the most salient factors associated with quality-of-life outcomes.
authors.affiliation: Houston Center Quality of Care and Utilization Studies, Dept. of Psychiatry and Behavioral Sciences, Houston, TX, USA. jcully@bcm.tmc.edu
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Cully
authors.forename: David P
authors.initials: DP
authors.lastname: Graham
authors.forename: Melinda A
authors.initials: MA
authors.lastname: Stanley
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Ferguson
authors.forename: Amir
authors.initials: A
authors.lastname: Sharafkhaneh
authors.forename: Julianne
authors.initials: J
authors.lastname: Souchek
authors.forename: Mark E
authors.initials: ME
authors.lastname: Kunik
mesh_terms: D000368:Aged; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000628:therapy; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology; D015928:Cognitive Behavioral Therapy / Q000379:methods; D015897:Comorbidity; D017281:Cost of Illness; D003863:Depression / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology* / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires