The breakdown of bilayer lipid membranes by dendrimers.
The BLM-system for studying the electrophysical properties of bilayer lipid membranes (BLM) was applied to investigate interactions between polyamidoamine (PAMAM) dendrimers and lipid bilayers. The cationic PAMAM G5 dendrimer effectively disrupted planar phosphatidylcholine membranes, while the hydroxyl PAMAM-OH G5 and carboxyl PAMAM G4.5 dendrimers had no significant effect on them.
Shcharbin
Dzmitry
D
Department of General Biophysics, University of Łódź, Łódź, Poland.
Drapeza
Alexander
A
Loban
Valeri
V
Lisichenok
Alexej
A
Bryszewska
Maria
M
D050091:Dendrimers / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry
D050091:Dendrimers; D008051:Lipid Bilayers; C104700:PAMAM Starburst; D011073:Polyamines