title: Gender differences in management and outcome of patients with acute myocardial infarction.
abstract: BACKGROUND
  The study objectives were to assess any gender differences in the application of diagnostic and therapeutic procedures and their impact on outcome in patients with acute myocardial infarction (AMI).
  
  
  METHODS
  Prospective cohort study of patients in the PRIAMHO II registry. 58 randomly selected public hospitals in Spain included 6209 patients with AMI admitted to Coronary/Critical Care Unit from May 15 to December 15 2000 with 1-year follow-up. Data were gathered on use of coronary angiography and reperfusion procedures, on a combined outcome variable (including death, reinfarction, postinfarction angina, and stroke during hospital stay), and on 28-day and 1-year mortality rates.
  
  
  RESULTS
  4641 (74.75%) of the patients were male and 1568 (25.5%) female. No gender differences in coronary angiography or reperfusion therapy use were found. However, female sex alongside age, use of reperfusion therapy, diabetes mellitus, previous revascularization, previous AMI, and higher Killip class were predictors of the combined outcome variable, with an adjusted OR of 1.21 (CI 95% 1.02-1.42).
  
  
  CONCLUSIONS
  No association was observed between the gender of patients with AMI and the application of diagnostic or therapeutic procedures. Nevertheless, female sex behaved as an independent adverse short-term prognostic factor.
authors.affiliation: Coronary Unit, Department of Critical and Emergency Care, Virgen de las Nieves, University Hospital, Granada, Spain. areina@fundacionhvn.org <areina@fundacionhvn.org>
authors.forename: Antonio
authors.initials: A
authors.lastname: Reina
authors.forename: Manuel
authors.initials: M
authors.lastname: Colmenero
authors.forename: Eduardo
authors.initials: E
authors.lastname: Aguayo de Hoyos
authors.forename: Fernando
authors.initials: F
authors.lastname: Arós
authors.forename: Helena
authors.initials: H
authors.lastname: Martí
authors.forename: Ramón
authors.initials: R
authors.lastname: Claramonte
authors.forename: José
authors.initials: J
authors.lastname: Cuñat
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries; D012737:Sex Factors; D016896:Treatment Outcome