title: [Double-blind placebo-controlled cow's milk challenge for children in general hospitals].
abstract: Every child with possible food allergies has the right to a double-blind, placebo-controlled cow's milk challenge. This test can be performed in the paediatric ward of a non-academic hospital. Challenge with other foodstuffs can lead to more serious side effects and therefore should be considered in a general hospital setting only after extensive experience with double-blind, placebo-controlled challenge for cow's milk has been obtained. Other items of international discussion on double-blind, placebo-controlled challenge in children are: the natural development of tolerance for cow's milk, IgE- versus non-IgE-mediated cow's milk allergy, and the exacerbation of pre-existing eczema during and after double-blind, placebo-controlled challenge.
authors.affiliation: Afd. Dermatologie, Universitair Medisch Centrum Utrecht, Wilhelmina Kinderziekenhuis, Centrum voor Kinderallergologie, Postbus 85.090, 3508 AB Utrecht. m.o.hoekstra@umcutrecht.nl
authors.forename: M O
authors.initials: MO
authors.lastname: Hoekstra
authors.forename: Y
authors.initials: Y
authors.lastname: Meijer
authors.forename: S G M A
authors.initials: SG
authors.lastname: Pasmans
authors.forename: A C
authors.initials: AC
authors.lastname: Knulst
mesh_terms: D000818:Animals; D002417:Cattle; D002648:Child; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D008892:Milk / Q000276:immunology*; D016269:Milk Hypersensitivity / Q000175:diagnosis* / Q000276:immunology*; D016032:Randomized Controlled Trials as Topic
chemical_list: D007073:Immunoglobulin E