The genetics of melanoma.
Melanoma is an increasingly common cancer and in order to direct preventative advice at those at risk, an understanding of susceptibility is crucial. This review summarizes what is known about common low-risk genes (such as those controlling red hair) and rare high-risk genes.
Bishop
Julia Newton
JN
University of Leeds, Cancer Research, UK.
Harland
Mark
M
Bishop
D Tim
DT
D005190:Family; D005260:Female; D019942:Genes, p16; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D010375:Pedigree; D019683:Penetrance; D012307:Risk Factors; D012878:Skin Neoplasms / Q000235:genetics*; D012880:Skin Pigmentation / Q000235:genetics