Prediction of false-positive recognition errors during Wada testing.
False-positive (FP) errors during recognition memory testing often interfere with interpretation of Wada test results. This study examined which clinical and neuropsychological variables provide the best prediction of these errors. Fifty-six patients completed the Wada test and the California Verbal Learning Test (CVLT). Subjects with three or more FP errors on the recognition trials of the CVLT were nearly twice as likely to exhibit FP responding during the Wada test. Further analysis indicates that FP errors during the Wada test appear to be the primary result of a stable and liberal response-bias rather than a result of any other neurological or procedure-related factor.
Barr
William B
WB
NYU Comprehensive Epilepsy Center, New York University School of Medicine, 10016, USA. william.barr@med.nyu.edu
Raghavan
Manoj
M
Kim Nelson
Peter
P
Devinsky
Orrin
O
D000328:Adult; D000654:Amobarbital / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000379:methods; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D007802:Language; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011237:Predictive Value of Tests; D021641:Recognition, Psychology / Q000187:drug effects* / Q000502:physiology; D012044:Regression Analysis; D014706:Verbal Learning / Q000187:drug effects / Q000502:physiology
D006993:Hypnotics and Sedatives; D000654:Amobarbital