The metabolic syndrome: risk factors and management.
This article reviews the criteria for the metabolic syndrome with a focus on the 5 components of the National Cholesterol Education Program definition (increased waist circumference, increased triglycerides, low high-density lipoprotein cholesterol, high blood pressure, and increased fasting glucose). Epidemiologic trends for the disorder and its prevalence are presented. The relation to cardiovascular disease and diabetes is discussed, as are findings from current studies explaining the risk factors. The article reviews the current recommendations for managing the metabolic syndrome including behavioral (weight reduction and increased physical activity) and pharmacological modalities. Relevant population-based studies and clinical trials are discussed with attention drawn to those clinical implications that are important for nurses to understand as they provide care to the growing population of clients expected to develop the metabolic syndrome.
Cassells
Holly B
HB
School of Nursing and Health Professions, University of the Incarnate Word, San Antonio, Tex 78209, USA. cassells@uiwtx.edu
Haffner
Steven M
SM
D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000032:analysis; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D003925:Diabetic Angiopathies / Q000453:epidemiology; D005951:Glucose Tolerance Test; D015438:Health Behavior; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000451:nursing / Q000628:therapy*; D012307:Risk Factors; D019821:Simvastatin / Q000627:therapeutic use
D000924:Anticholesteremic Agents; D001786:Blood Glucose; D019821:Simvastatin