title: Fertility, pregnancy, and delivery after biventricular repair for pulmonary atresia with an intact ventricular septum.
abstract: The objective of the present study to investigate fertility, pregnancy, and delivery in women with biventricular repair for pulmonary atresia with an intact ventricular septum (PAIVS). Using a nationwide registry (CONCOR), 37 patients with pulmonary atresia were identified, 6 of whom (aged 21 to 34 years) had biventricular repair for PAIVS. Three PAIVS patients had a total of 5 pregnancies, including 1 abortion and 1 ectopic pregnancy. Besides minor noncardiac complications, the 3 live-birth pregnancies were successful. None of the women reported infertility or irregularities (hypermenorrhea, dysmenorrhea, polymenorrhoea, oligomenorrhea, or amenorrhea) of their natural menstrual cycle. In conclusion, successful pregnancy in women with biventricular repair for PAIVS is possible, and only minor complications were observed. Infertility and menstrual cycle disorders do not appear to be more prevalent than usual.
authors.affiliation: Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands. w.drenthen@thorax.umcg.nl
authors.forename: Willem
authors.initials: W
authors.lastname: Drenthen
authors.forename: Petronella G
authors.initials: PG
authors.lastname: Pieper
authors.forename: Jolien W
authors.initials: JW
authors.lastname: Roos-Hesselink
authors.forename: Nicole
authors.initials: N
authors.lastname: Zoon
authors.forename: Adriaan A
authors.initials: AA
authors.lastname: Voors
authors.forename: Barbara J M
authors.initials: BJ
authors.lastname: Mulder
authors.forename: Arie P J
authors.initials: AP
authors.lastname: van Dijk
authors.forename: Hubert W
authors.initials: HW
authors.lastname: Vliegen
authors.forename: Krystyna M
authors.initials: KM
authors.lastname: Sollie
authors.forename: Tjark
authors.initials: T
authors.lastname: Ebels
authors.forename: Dirk J
authors.initials: DJ
authors.lastname: van Veldhuisen
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods*; D036861:Delivery, Obstetric; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006346:Heart Septum; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000601:surgery*; D011256:Pregnancy Outcome; D018633:Pulmonary Atresia / Q000601:surgery*