title: Hirschsprung's disease, a rare precipitating factor in neonatal perforated Meckel's diverticulum.
abstract: Perforation of Meckel's diverticulum (MD) during the neonatal period may occur in the presence of distal colon obstruction. Herein, we describe a unique case of a 2-day-old infant that presented with pneumoperitoneum, in which a perforated MD was induced by distal intestinal obstruction secondary to total colonic aganglionosis. In the setting of neonatal perforated MD found intraoperatively, the determination of the possible precipitating etiology is necessary. The clinical history of delayed passage of meconium is emphasized, and either a rectal or colon biopsy is recommended intraoperatively to avoid overlooking the associated presence of Hirschsprung's disease.
authors.affiliation: Section of Pediatric Surgery, Department of Surgery, National Cheng Kung University Hospital, Tainan 704, Taiwan. edsy@mail.ncku.edu.tw
authors.forename: E D
authors.initials: ED
authors.lastname: Sy
authors.forename: Y S
authors.initials: YS
authors.lastname: Shan
authors.forename: Y R
authors.initials: YR
authors.lastname: Yang
authors.forename: H M
authors.initials: HM
authors.lastname: Tsai
authors.forename: C H
authors.initials: CH
authors.lastname: Lin
mesh_terms: D003125:Colostomy; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D005260:Female; D006627:Hirschsprung Disease / Q000150:complications* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007412:Intestinal Fistula / Q000209:etiology / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology* / Q000601:surgery; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery; D008467:Meckel Diverticulum / Q000150:complications* / Q000601:surgery; D015985:Precipitating Factors; D012086:Reoperation