First detection of group C rotavirus in patients with gastroenteritis in Slovenia.
Group C rotaviruses are associated with sporadic gastroenteritis and outbreaks of diarrhea in children and adults worldwide. Three cases with group C rotavirus infection are described, and the molecular characterization of the gene for the major capsid protein VP6 is reported. Patients described in this report were 10 years old or more and had mild to moderate clinical symptoms. A high nucleotide (>98%) and amino acid (100%) identity was observed among all three isolated Slovenian group C rotavirus strains. The similar identity is confirmed of Slovenian strains with other human group C rotavirus isolates, which were seen to cluster separately from the animal group C rotavirus isolates by a phylogenetic analysis. This is the first report of group C rotavirus detection in Slovenia.
Steyer
Andrej
A
Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia. andrej.steyer@mf.uni-lj.si
Poljsak-Prijatelj
Mateja
M
Bufon
Tatjana
T
Sedmak
Marjeta
M
Vidmar
Ludvik
L
Mijovski
Janet Zimsek
JZ
Marin
Jozica
J
D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D002648:Child; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012401:Rotavirus / Q000145:classification / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology; D017524:Slovenia / Q000453:epidemiology; D013045:Species Specificity
D000956:Antigens, Viral; D036022:Capsid Proteins; C061332:VP6 protein, Rotavirus