Hospital-acquired Bordetella bronchiseptica infection following hematopoietic stem cell transplantation.
Two patients who had undergone nonmyeloablative allogeneic stem cell transplantation 53 and 112 days earlier and were being monitored at the same transplant center developed severe Bordetella bronchiseptica infections within 3 days of each other. Pulsed-field gel electrophoresis analysis indicated that the isolates from the two cases were identical. Neither patient had had direct contact with animals since transplantation. These findings strongly support nosocomial transmission of B. bronchiseptica.
Huebner
Elizabeth S
ES
Department of Medicine, Vanderbilt University Hospital, Medical Center, 4605 TVC, Nashville, TN 37232-5310, USA.
Christman
Brian
B
Dummer
Stephen
S
Tang
Yi-Wei
YW
Goodman
Stacey
S
D001885:Bordetella Infections / Q000382:microbiology / Q000635:transmission*; D016950:Bordetella bronchiseptica / Q000145:classification / Q000302:isolation & purification*; D003428:Cross Infection / Q000382:microbiology / Q000635:transmission*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D018380:Hematopoietic Stem Cell Transplantation; D006689:Hodgkin Disease / Q000150:complications / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D009101:Multiple Myeloma / Q000150:complications / Q000628:therapy
D004269:DNA, Bacterial