title: Clinical inquiries. What best prevents exercise-induced bronchoconstriction for a child with asthma?
abstract: Inhaled short-acting beta-agonists (SABAs) are most effective in preventing exercise-induced bronchoconstriction, followed by inhaled mast cell stabilizers and anticholinergic agents (strength of recommendation [SOR]: A, multiple randomized control trials [RCTs]). Less evidence supports the use of leukotriene antagonists and inhaled corticosteroids, either individually or in combination (SOR: B). Underlying asthma, which commonly contributes to exercise-induced bronchoconstriction, should be diagnosed and controlled first (SOR: C).
authors.affiliation: University of Colorado, Denver, CO, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Preston
authors.forename: Mark
authors.initials: M
authors.lastname: Cucuzella
authors.forename: Barbara
authors.initials: B
authors.lastname: Jamieson
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D001249:Asthma / Q000209:etiology / Q000517:prevention & control*; D002648:Child; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D015444:Exercise; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008407:Mast Cells / Q000187:drug effects
chemical_list: D000318:Adrenergic beta-Agonists; D018680:Cholinergic Antagonists