[Management of patients with non-functioning gastroentero-pancreatic neuroendocrine tumours].
The Authors examine the feasibility of diagnosing non-functioning gastroentero-pancreatic neuroendocrine tumours preoperatively or intraoperatively, with particular reference to laboratory examinations and octreoscan scintigraphy, which are capable of conditioning the surgical treatment and subsequent follow-up. Of the 4 cases reported here: three presented multiple intestinal localizations, and in only one case the origin of the primitive carcinoma was undefined. The suspicion of a non-functioning neuroendocrine tumour must be considered when yellowish or ochre-coloured intestinal lesions are found intraoperatively. Determination of specific markers and octreoscan scintigraphy must be performed without awaiting histological confirmation. Surgery plays a fundamental role in the debulking of these carcinomas. However, medical therapy with the aid of specific laboratory examinations and octreoscan scintigraphy may improve the long-term survival.
Guarnieri
Alfredo
A
AOU Senese UOC Chirurgia 2 - Siena.
Tirone
Andrea
A
Pallucca
Eleonora
E
Testa
Michele
M
Piccolomini
Alessandro
A
Vuolo
Giuseppe
G
Savelli
Vinno
V
Di Cosmo
Leonardo
L
Verre
Luigi
L
Carli
Anton Ferdinando
AF
D000368:Aged; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000175:diagnosis* / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000601:surgery*