title: Short communication: antimicrobial drug susceptibility of Staphylococcus aureus from subclinical bovine mastitis in Italy.
abstract: The antimicrobial susceptibility of 68 Staphylococcus aureus isolates collected during 2004 from milk of cows affected by subclinical mastitis was examined. The antimicrobial agents tested were the beta-lactams, penicillin G, amoxicillin, ampicillin, cloxacillin, amoxicillin + clavulanate, cephalonium, and cefoperazone; and other drugs including lincomycin, oxytetracycline, doxycycline, and kanamycin. Minimum inhibitory concentrations recorded show that only certain beta-lactamase-resistant penicillins (specifically cloxacillin) or penicillin combinations (amoxicillin + clavulanate) were consistently effective against Staph. aureus, whereas the other beta-lactam derivatives and drugs from other pharmacological groups were either moderately effective or ineffective. Thus, beta-lactamase-resistant penicillins are to be considered the antimicrobial agents of choice for treatment of bovine mastitis resulting from infection by Staph. aureus.
authors.affiliation: Department of Veterinary Pathology, Hygiene and Public Health, University of Milan, via Celoria 10, 20133 Milan, Italy. paolo.moroni@unimi.it
authors.forename: P
authors.initials: P
authors.lastname: Moroni
authors.forename: G
authors.initials: G
authors.lastname: Pisoni
authors.forename: M
authors.initials: M
authors.lastname: Antonini
authors.forename: R
authors.initials: R
authors.lastname: Villa
authors.forename: P
authors.initials: P
authors.lastname: Boettcher
authors.forename: S
authors.initials: S
authors.lastname: Carli
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001426:Bacterial Proteins / Q000187:drug effects*; D002417:Cattle; D002511:Cephalosporins / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D005260:Female; D007558:Italy; D055231:Lincosamides; D018942:Macrolides / Q000008:administration & dosage; D008414:Mastitis, Bovine / Q000188:drug therapy / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000008:administration & dosage; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000187:drug effects*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000662:veterinary
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002511:Cephalosporins; D055231:Lincosamides; D018942:Macrolides; D010406:Penicillins; D002981:Clindamycin; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; C030182:phosphocarrier protein HPr