title: [Pathological character and treatment of epithelial-myoepithelial carcinoma of salivary gland].
abstract: OBJECTIVE
  To review and evaluate pathologic features and treatment of epithelial-myoepithelial.
  
  
  METHODS
  Retrospectively reviewed 14 cases' pathological and clinical materials of epithelial-myoepithelial carcinoma of salivary gland. Eight cases origine from parotid gland, 2 cases from hard palate, 3 cases from submandibular gland and 1 case from nasal cavity. Three cases were performed induction chemotherapy preoperation. One case had palliative radiotherapy. Thirteen cases were performed radical surgery and 6 cases had radiotherapy postoperation.
  
  
  RESULTS
  Tumor arisen mostly from parotid gland and neck lymph node metastasis rate was 14.28% (2/14). The survival rate was calculated with Kaplan-Meier method. The overall 3-, 5- and 10-year survival rate were 67.20%, 45.49% and 17.06%. Its histological characteristics were inner layer composed by adenoid cells and outer layer composed by myoepithelial cells. Immunohistochemical exam show cytokeratin, S-100 and actin reaction positive.
  
  
  CONCLUSIONS
  Epithelial-myoepithelial carcinoma easily develops recurrence. It is sensitivity to radiotherapy and chemotherapy to some extent. It is suitable to adopt surgical treatment as primary modality combined with other therapies.
authors.affiliation: Department of Head and Neck, Cancer Center, Sun Yat-sen University, Guangzhou, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Guo-hao
authors.initials: GH
authors.lastname: Wu
authors.forename: Fu-jin
authors.initials: FJ
authors.lastname: Chen
authors.forename: Quan
authors.initials: Q
authors.lastname: Zhang
authors.forename: Mao-wen
authors.initials: MW
authors.lastname: Wei
authors.forename: Wen-kuan
authors.initials: WK
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000628:therapy; D012469:Salivary Glands / Q000473:pathology