[The effects of enteral nutrition vs parenteral nutrition on gastric motility and gastroenteric hormones after subtotal gastrectomy: a perspective randomized compared clinical trial].
OBJECTIVE
To compare the effects of enteral nutrition (EN) and parenteral nutrition (PN) on gastric motility and gastroenteric hormones after subtotal gastrectomy. Try to find the possible prognosticating marks for the postoperative gastroparesis.


METHODS
Forty-one patients after gastrectomy were randomly divided into EN group (n = 20) and PN group (n = 21). From the first day after operation (POD + 1) to the seventh day (POD + 7), patients received either EN (EN group) or PN (PN group) with isocaloric and isonitrogenous intake. Serum gastrin (GAS), plasma motilin (MTL) and plasma cholecystokinin (CCK) were measured on preoperative day, POD + 1 and POD + 7. Electrogastrography (EGG) was measured on preoperative day, and POD + 7.


RESULTS
On the seventh day after gastrectomy, plasma MTL and CCK levels in EN group are higher than those in PN group. There is no difference in GAS between two groups. EGG in EN group is better than that in PN group postoperatively.


CONCLUSIONS
The level of gastroenteric hormones and the gastric motility are decreased significantly after subtotal gastrectomy. In contrast with PN, EN could accelerate the recovery of some gastroenteric hormones and the gastric motility after subtotal gastrectomy. GAS, MTL, CCK and EGG are not accurate enough as the marks for prognosticating the postoperative gastroparesis.
Zhang
Qun
Q
Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Yu
Jian-chun
JC
Ma
Zhi-qiang
ZQ
Kang
Wei-ming
WM
Ke
Mei-yun
MY
Qian
Jia-ming
JM
D000293:Adolescent; D000328:Adult; D000368:Aged; D004750:Enteral Nutrition; D005260:Female; D005743:Gastrectomy / Q000379:methods / Q000451:nursing*; D005746:Gastric Emptying / Q000502:physiology*; D005768:Gastrointestinal Hormones / Q000097:blood*; D018589:Gastroparesis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies
D005768:Gastrointestinal Hormones