Proprioception: a channel for body sense in the worm.
A TRP family cation channel has been found to be critical for proprioception in the nematode Caenorhabditis elegans. This is a starting point for understanding conserved mechanotransduction mechanisms in proprioceptor neurons, and for deciphering how sensory feedback can function within a defined neural circuit to produce coordinated patterns of motor activity.
Schafer
William R
WR
Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093, USA. wschafer@ucsd.edu
D000483:Alleles; D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D017353:Gene Deletion; D007395:Interneurons / Q000378:metabolism; D008124:Locomotion / Q000235:genetics / Q000502:physiology; D011434:Proprioception / Q000235:genetics / Q000502:physiology*; D050052:TRPC Cation Channels / Q000235:genetics / Q000378:metabolism / Q000502:physiology*
D029742:Caenorhabditis elegans Proteins; C509780:TRP-4 channel, C elegans; D050052:TRPC Cation Channels