The ocular manifestations of atopic dermatitis and rosacea.
Atopic dermatitis and rosacea are chronic diseases that have both dermatologic and ocular manifestations. The occurrence of ocular disease is often proportionately higher than that of dermatologic disease. Even if the skin abnormalities appear well controlled, these patients require ophthalmic evaluation as well. Optimal management usually requires a team approach that includes internists, dermatologists, and ophthalmologists. Both disorders are characterized by acute exacerbations and require maintenance therapy for control. Exacerbations need aggressive treatment to limit ocular signs and symptoms and to reduce ocular inflammation that can lead to permanent visual loss. Topical corticosteroid use, although at times needed, should be minimized for both disorders. Future research will continue to emphasize the use of steroid-sparing and immune-modulating agents that have the potential to provide long-lasting anti-inflammatory control with a more favorable side-effect profile.
Eiseman
Andrew S
AS
Eye Clinic, Walter Reed Army Medical Center, Washington, DC 20307, USA. Andrew.Eiseman@na.amedd.army.mil
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D001766:Blindness / Q000139:chemically induced / Q000209:etiology; D002908:Chronic Disease; D003876:Dermatitis, Atopic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005128:Eye Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D012393:Rosacea / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D003879:Dermatologic Agents