The prognosis of agenesis of the corpus callosum might mostly be favourable.
The post-natal development of 6 patients with complete agenesis of the corpus callosum was assessed. The diagnosis of agenesis of the corpus callosum had been suspected prenatally in 3 cases. In the remaining 3 cases diagnostic neuro-imaging was performed because of partial seizures (n = 2) and pendular nystagmus (n = 1). The neurological examination was normal in all patients with the exception of nystagmus in one. The neuro-developmental outcome was found to be normal in all 6 patients. In conclusion, these data suggest that good outcome is predominant in agenesis of the corpus callosum.
Ramelli
Gp
G
Department of Paediatrics, Ospedale San Giovanni, 6500 Bellinzona, Switzerland. gpramelli@bluewin.ch
Zanda
N
N
Wyttenbach
M
M
Bronz
L
L
Schnider
A
A
D000293:Adolescent; D000328:Adult; D061085:Agenesis of Corpus Callosum; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D011379:Prognosis; D013557:Switzerland