Cognitive profile of neurofibromatosis type 1.
General consensus has yet to be reached with regard to the exact cognitive profile of children with neurofibromatosis type 1 (NF1). The current overview seeks to provide a more comprehensive review of the literature by examining studies that have specifically compared individuals with NF1 to siblings, controls, and/or norms. We also examined results of studies that compared individuals with NF1 with various manifestations to each other. Consistent with previous reviews, no clear cognitive profile emerged; however, greater insight into patterns was obtained. Additionally, future directions for research on NF1 were suggested.
Levine
Terry M
TM
Kennedy Krieger Institute, Department of Developmental Cognitive Neurology, Baltimore, MD 21205, USA.
Materek
April
A
Abel
Jessica
J
O'Donnell
Madeline
M
Cutting
Laurie E
LE
D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000209:etiology*; D006801:Humans; D007360:Intelligence / Q000502:physiology; D007806:Language Disorders / Q000209:etiology; D009422:Nervous System Diseases; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000503:physiopathology*; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D010468:Perceptual Disorders / Q000209:etiology