title: Optimization of process parameters for reduction of gossypol levels in cottonseed meal by Candida tropicalis ZD-3 during solid substrate fermentation.
abstract: The objective of this work is to optimize the process parameters for detoxification of gossypol in cottonseed meal (CSM) by Candida tropicalis ZD-3 during solid substrate fermentation (SSF). The maximum detoxification efficiency of gossypol was achieved by employing the substrate, which consists of 70% of CSM, 20% of corn flour and 10% of wheat bran. The optimum fermentation conditions for gossypol detoxification are incubation period of 48h, incubation temperature at 30 degrees Celsius, inoculum level 5% v/w, moisture content of solid substrate 50% and pH in nature. Adding minerals solution to CSM substrate benefit fermentation detoxification.
authors.affiliation: Key Laboratory of Molecular Animal Nutrition, Ministry of Education, Animal Science College, Zhejiang University, Hangzhou 310029, PR China.
authors.forename: Wen-Ju
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Zi-Rong
authors.initials: ZR
authors.lastname: Xu
authors.forename: Shun-Hong
authors.initials: SH
authors.lastname: Zhao
authors.forename: Jun-Fang
authors.initials: JF
authors.lastname: Jiang
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Wang
authors.forename: Xiang-Hua
authors.initials: XH
authors.lastname: Yan
mesh_terms: D000821:Animal Feed / Q000032:analysis; D041022:Candida tropicalis / Q000378:metabolism*; D003369:Cottonseed Oil / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D005516:Food Microbiology; D003368:Gossypium; D006072:Gossypol / Q000032:analysis / Q000378:metabolism*; D008658:Inactivation, Metabolic
chemical_list: D003369:Cottonseed Oil; D006072:Gossypol