[Primary mediastinal germ cell tumors].
Primary mediastinal germ cell tumors account for approximately 10% to 20% of all neoplasms of the mediastinum. It is generally accepted that they represent the malignant transformation of germinal elements without a gonadal focus. These tumors can be classified as teratomas, seminomas, nonseminomatous (yolk sac tumor, embryonal carcinoma, choriocarcinoma) and combined germ-cell tumors without teratomatous components. This review purposes to discuss the different primary mediastinal germ-cell tumors, their clinical presentation and options for treatment.
Couto
Wilson José
WJ
Departamento de Cirurgia Torácica, Centro de Tratamento e Pesquisa, Hospital do Câncer A.C. Camargo, Rua Prof. Antonio Prudente 211, Liberdade, Cep. 01509-900 São Paulo/SP.
Gross
Jefferson Luiz
JL
Deheinzelin
Daniel
D
Younes
Riad Naim
RN
D006801:Humans; D008479:Mediastinal Neoplasms / Q000145:classification / Q000473:pathology* / Q000628:therapy; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000145:classification / Q000473:pathology* / Q000628:therapy; D011379:Prognosis