Synthesis of highly substituted N-hydroxyindoles through 1,5-addition of carbon nucleophiles to in situ generated unsaturated nitrones.
Nicolaou
K C
KC
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Estrada
Anthony A
AA
Lee
Sang Hyup
SH
Freestone
Graeme C
GC
D007211:Indoles / Q000138:chemical synthesis*; D008958:Models, Molecular; D008968:Molecular Conformation; D009589:Nitrogen Oxides / Q000737:chemistry*
D007211:Indoles; D009589:Nitrogen Oxides; C015388:nitrones