[Morphoimmunohistochemical differential diagnosis of B-cell lymphomas].
The paper considers the stages of B-cell differentiation at the level of central (bone marrow) and peripheral (lymph node) organs of the immune system. The immunophenotype of B-cell lymphoid tumors and their "normal" cell analogues was compared, by taking into account 4 stages of B-cell differentiation: bone marrow B-cell precursors, mature B-cell, B-cell with follicular differentiation, postfollicular B-cell. Algorithms of immunohistochemical differential diagnosis of B-cell lymphomas are proposed when their morphological patterns are similar.
Kovrigina
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Probatova
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D000943:Antigens, Differentiation / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D002454:Cell Differentiation / Q000276:immunology; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000145:classification* / Q000175:diagnosis* / Q000276:immunology
D000943:Antigens, Differentiation