[Advance in association studies of major histocompatibility complex (MHC) gene polymorphisms with traits of resistance against infectious disease in chickens].
Chicken is a main poultry in China. Molecular breeding for disease resistance plays an important role in the control of diseases, especially infectious diseases. Choice of genes for disease resistance is the key technology of molecular breeding. The MHC is of great interest to poultry breeding scientists for its extraordinary polymorphism and close relation with traits of resistance against infectious diseases. The article gives a detailed introduction about the association of MHC gene polymorphisms with traits of resistance against infectious diseases in chickens and looks towards the future of application of MHC in molecular breeding of chicken for disease resistance.
Li
Guo-Qin
GQ
Institute of Animal Science and Veterinary Medicine, Zhejiang Academy of Agricultural Science, Hangzhou 310021, China. ligq@zaas.org
Lu
Li-Zhi
LZ
Wang
De-Qian
DQ
Shen
Jun-Da
JD
Tao
Zheng-Rong
ZR
Zhao
Ai-Zhen
AZ
Yuan
Ai-Ping
AP
D000818:Animals; D001947:Breeding; D002645:Chickens / Q000235:genetics* / Q000276:immunology; D007113:Immunity, Innate; D008285:Major Histocompatibility Complex; D011110:Polymorphism, Genetic; D011201:Poultry Diseases / Q000235:genetics* / Q000276:immunology / Q000382:microbiology / Q000821:virology; D019655:Quantitative Trait, Heritable