A novel synthesis of beta-lactam fused cyclic enediynes by intramolecular Kinugasa reaction.
A general synthetic route to beta-lactam-fused enediynes by intramolecular Kinugasa reaction has been successfully developed. The method has widened the scope of Kinugasa reaction in the synthesis of sensitive systems like the one described in this communication.
Pal
Runa
R
Bioorganic Laboratory, Department of Chemistry, Indian Institute of Technology, Kharagpur, India.
Basak
Amit
A
D003500:Cyclization; D053281:Enediynes / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry
D053281:Enediynes; D047090:beta-Lactams