title: [One case report of primary penile malignant lymphoma (with a review of 24 case reports)].
abstract: OBJECTIVE
  To investigate the early diagnosis and early treatment of primary penile malignant lymphoma.
  
  
  METHODS
  One case of rare primary penile malignant lymphoma was studied with regard to its primary clinical process and characteristics, differential diagnosis and therapeutic method. The application value of the immunohistochemical features, in clinical diagnosis was analyzed.
  
  
  RESULTS
  Surgical treatment of removing the penis, testes and scrotum was carried out, followed by chemotherapy went. The immunohistochemical tests showed CD56, granzyme B, perforin and cytoplasmic CD3epsilon to be positive, and surface CD3 negative.
  
  
  CONCLUSIONS
  Primary malignant lymphoma of the penis, though rare clinically, may be treated effectively if diagnosed early. Wedge biopsy with histological examination and immunohistochemical tests is the most common method for definite diagnosis.
authors.affiliation: Department of Urology, Shanghai Ninth People's Hospital Affiliated to Medical School of Shanghai Jiaotong University, Shanghai 200011, China.
authors.forename: Hai-jun
authors.initials: HJ
authors.lastname: Yao
authors.forename: Jun
authors.initials: J
authors.lastname: Ying
authors.forename: Zhong
authors.initials: Z
authors.lastname: Wang
authors.forename: De-hong
authors.initials: DH
authors.lastname: Yao
authors.forename: Xiao-min
authors.initials: XM
authors.lastname: Ren
authors.forename: Yong-yang
authors.initials: YY
authors.lastname: Bao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D008223:Lymphoma / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy