title: [Studies on chemical constituents in root of Phlomis medicinalis I].
abstract: OBJECTIVE
  To study the chemical constituents in root of Phlomis medicinalis.
  
  
  METHODS
  The compounds were isolated and repeatedly purified on macroporous resin, silica gel column chromatography, TLC and Prep-HPLC and the structures were elucidated by physico-chemical properties and NMR spectra.
  
  
  RESULTS
  Eight compounds were obtained and elucidated as 5-Hydroxy-7-methoxy-4, 6-dimethylphthalide (1), 4-hydroxymethyl-2-furaldehyde (2) and six iridoid glucosides: 6-O-acetyl-shanzhiside methyl ester (3), 8-O-acetyl-shanzhiside methyl ester (4), shanzhiside methyl ester (5), sesamoside (6), phloyoside II (7) and dehydropentstemoside (8).
  
  
  CONCLUSIONS
  All the compounds were isolated from the plant for the first time and 1 and 3 were obtained from the plants of Phlomis for the first time.
authors.affiliation: College of Chinese Materia Medica, Beijing University of Traditional Chinese Medicine.
authors.forename: Zhen-xi
authors.initials: ZX
authors.lastname: Yu
authors.forename: Gang-li
authors.initials: GL
authors.lastname: Wang
authors.forename: Ciren
authors.initials: C
authors.lastname: Bianba
authors.forename: Rui-chao
authors.initials: RC
authors.lastname: Lin
mesh_terms: D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D031345:Phlomis / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D011714:Pyrans / Q000737:chemistry / Q000302:isolation & purification*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C529015:5-hydroxy-7-methoxy-4,6-dimethylphthalide; C529016:6-O-acetylshanzhiside methyl ester; D001572:Benzofurans; D005960:Glucosides; D010936:Plant Extracts; D011714:Pyrans; D013729:Terpenes; C407310:phloyoside II; C099471:sesamoside; C099473:8-O-acetyl shanzhiside methyl ester