title: [Cocaine abuse attended in the emergency department: an emerging pathology].
abstract: OBJECTIVE
  The consumption of cocaine has increased in Spain in recent years, leading to a probable increase in overdoses. The associated use of other drugs of abuse may be increasing the toxicity of cocaine, and therefore, increasing consultations to the emergency department (ED).
  
  
  METHODS
  We collected patients seen by the ED of our hospital who reported cocaine consumption in the previous hours. The relationship between cocaine consumption and the reason for attending the ED was analysed. We reviewed the medical records of a sample of overdoses to determine the clinical profile.
  
  
  RESULTS
  During the period 2002-2004, 745 patients were detected (average age 31 years, 68% males). The annual distribution was 223 cases in 2002, 232 in 2003, and 290 in 2004. Fifty-three percent of patients attended the ED at the weekend and 53% from 0:00 to 12:00 h. The main drugs associated with cocaine consumption were ethyl alcohol (38%), opiates (14%), cannabis (13%) and amphetamine derivatives (9%). Cocaine was the substance causing clinical symptoms in 70% of cases. The main reasons for attending the ED were anxiety or agitation (48%) and thoracic pain or palpitations (25%). Eleven percent of cases required hospital admission (19 intensive care unit) and 3 patients died.
  
  
  CONCLUSIONS
  The consumption of cocaine, almost always associated with other drugs of abuse, has generated an increase in patients attending the ED. Although mortality is low, cocaine consumption generates substantial morbidity and frequent hospital admissions.
authors.affiliation: Servicio de Medicina Interna, Hospital Clinic, Barcelona. 33041esg@comb.es
authors.forename: Eduard
authors.initials: E
authors.lastname: Sanjurjo
authors.forename: Elisabet
authors.initials: E
authors.lastname: Montori
authors.forename: Santiago
authors.initials: S
authors.lastname: Nogué
authors.forename: Miquel
authors.initials: M
authors.lastname: Sánchez
authors.forename: Perre
authors.initials: P
authors.lastname: Munné
mesh_terms: D000293:Adolescent; D000328:Adult; D019970:Cocaine-Related Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013030:Spain / Q000453:epidemiology