title: [Comparison of ILM peeling with and without the use of indocyanine green. Functional results for idiopathic macular hole after pars plana vitrectomy].
abstract: BACKGROUND
  Pars plana vitrectomy with internal limiting membrane (ILM) peeling is the best known therapy for idiopathic macular holes. Indocyanine green (ICG) is useful for staining the ILM, although there is a dose related toxic effect on the inner retinal layers. We compared outcome results with and without the use of ICG.
  
  
  METHODS
  Data from 61 patients with idiopathic macular holes, who underwent macular hole surgery were analyzed retrospectively. ICG was used on 36 eyes while for 25 eyes it was not used. After calculating logMAR, differences in visual acuity between both groups were analyzed for significance using the Mann-Whitney-U-Test.
  
  
  RESULTS
  The logMAR for the entire group was 0.71+/-0.30 (20/100) preoperatively, after 1 month 0.71+/-0.36 (20/100), after 3 months 0.57+/-0.26 (20/80), after 6 months 0.54+/-0.38 (20/66) and after 12 months 0.36+/-0.32 (20/50). There were no significant differences between groups.
  
  
  CONCLUSIONS
  There seem to be no significant differences in the development of visual acuity and the occlusion rate between patients treated with or without the use of ICG.
authors.affiliation: Klinik für Ophthalmologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Hegewischstrasse 2, 24105, Kiel, Germany. fruefer@ophthalmol.uni-kiel.de
authors.forename: F
authors.initials: F
authors.lastname: Rüfer
authors.forename: A
authors.initials: A
authors.lastname: Frimpong-Boateng
authors.forename: A
authors.initials: A
authors.lastname: Bunse
authors.forename: J
authors.initials: J
authors.lastname: Roider
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D019773:Epiretinal Membrane / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007208:Indocyanine Green / Q000009:adverse effects; D008297:Male; D012167:Retinal Perforations / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D014787:Vision Tests; D014821:Vitrectomy / Q000379:methods*
chemical_list: D007208:Indocyanine Green