Cutaneous metastasis of pheochromocytoma in multiple endocrine neoplasia IIB.
Pheochromocytoma is a rare tumor originating from neuroectodermic cells. Only 10% of these tumors are malignant. There are many familial forms of this tumor, including multiple endocrine neoplasia type II, Von Hippel-Lindau syndrome, and neurofibromatosis type I. Skin manifestations of pheochromocytoma are rare, and cutaneous metastasis in patients with multiple endocrine neoplasia IIB has never been described. The case of a patient with multiple endocrine neoplasia IIB who presented malignant pheochromocytoma with multiple cutaneous metastasis is described.
Duquia
Rodrigo Pereira
RP
Catholic University of Pôrto Alegre, Brazil. rodrigoduquia@terra.com.br
de Almeida
Hiram Larangeira
HL
Traesel
Moacir
M
Jannke
Heitor Alberto
HA
D000310:Adrenal Gland Neoplasms / Q000737:chemistry / Q000473:pathology*; D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D018814:Multiple Endocrine Neoplasia Type 2b / Q000737:chemistry / Q000473:pathology*; D010673:Pheochromocytoma / Q000737:chemistry / Q000556:secondary*; D012878:Skin Neoplasms / Q000737:chemistry / Q000556:secondary*