[The peculiarities of 24-hour arterial pressure monitoring in patients with arterial hypertension under the conditions of North].
Circadian blood pressure profile (CBPP) is considered to be a functional characteristic of the cardiovascular system, which reflects the severity and pathogenetic peculiarities of arterial hypertension. At the same time, blood pressure dynamics also depends on the state of environmental factors, the heliogeophysical medium in particular, which plays an important part in the formation of northern ecology. The purpose of the study was to evaluate the peculiarities of the correlations between morphofunctional characteristics of the cardiovascular system, circadian blood pressure rhythms in particular, and heliogeophysical environmental factors under North conditions. The data of 24-hour blood pressure monitoring (BPM) and echoCG, and the heliogeophysical factors during different ontogenesis periods in 257 residents of North and medium latitudes with arterial hypertension (AH), were analyzed. A considerable disorder of CBPP, manifesting by an insufficient (less than 10%) night-time decrease in blood pressure, was revealed in 46% of the hypertensive subjects, who lived in North. The circadian rhythm amplitude was low in cases of a high degree of coupling of hemodynamic indices with geomagnetic activity during the study. The study did not reveal such CBPP disturbances in AH patients living in medium latitudes. Left ventricular hypertrophy was more frequent in patients with an insufficient night-time BP decrease vs. patients with a normal one (39.7% and 22.2%, respectively). A test allowing evaluation of the hemodynamic mechanisms of magnetotropic responses to changes in heliogeophysical environment, was developed. This diagnostic test uses EchoCG and testing exposure to constant magnetic field, and is based on evaluation of changes in central hemodynamics allowing for the balance of geomagnetic activity during early ontogenesis and during the study.
Poliakov
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D000328:Adult; D000368:Aged; D002391:Catchment Area, Health; D002980:Climate; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012426:Russia / Q000453:epidemiology; D012720:Severity of Illness Index