title: Quantum catalysis in enzymes: beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005.
abstract: How do enzymes work? What is the physical basis of the phenomenal rate enhancements achieved by enzymes? Do we have a theoretical framework that accounts for observed catalytic rates? These are the foremost questions-with particular emphasis on tunnelling phenomena-debated at this Discussion Meeting by the leading practitioners in the field.
authors.affiliation: Faculty of Life Sciences, University of Manchester, Jackson's Mill, Manchester, UK. nigel.scrutton@manchester.ac.uk
authors.forename: Nigel S
authors.initials: NS
authors.lastname: Scrutton
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Sutcliffe
authors.forename: P
authors.initials: P
authors.lastname: Leslie Dutton
mesh_terms: D055162:Biocatalysis; D003198:Computer Simulation; D004583:Electrons; D004798:Enzymes / Q000737:chemistry / Q000502:physiology*; D006859:Hydrogen / Q000737:chemistry; D007700:Kinetics; D008956:Models, Chemical; D010084:Oxidation-Reduction; D011789:Quantum Theory
chemical_list: D004798:Enzymes; D006859:Hydrogen