title: Testing for genetic structure in different urban Argentinian populations.
abstract: Fifteen autosomal short tandem repeat (STR) markers (D3S1358, HUMTH01, D21S11, D18S51, PENTA E, D5S818, D13S317, D7S820, D16S539, CSF1PO, PENTA D, HUMvWA, D8S1179, HUMTPOX, FGA) were analyzed in 1734 individuals living in urban areas of cities from six different Argentinian provinces (Buenos Aires, Neuquén, Tucumán, La Pampa, San Luis, Santa Cruz) in order to determine if a common urban database could be used in Argentina for forensic purposes. Frequencies estimates, Hardy-Weinberg equilibrium (HWE), and other parameters of forensic interest were computed. Comparisons between the six populations, and with published data from one Native American population from Argentina and other urban populations from Argentina and Europe were also performed. Our results reveal evidences for population structure, both when testing for genetic differentiation and when comparing frequencies distributions between different pairs of populations. Therefore, caution should be taken when using a common pooled database with general forensic purposes in Argentina.
authors.affiliation: PRICAI-Fundacion Favaloro, Av. Belgrano 1782, 1er Subsuelo, 1093 Capital Federal, Buenos Aires, Argentina.
authors.forename: Ulises
authors.initials: U
authors.lastname: Toscanini
authors.forename: Leonor
authors.initials: L
authors.lastname: Gusmão
authors.forename: Gabriela
authors.initials: G
authors.lastname: Berardi
authors.forename: António
authors.initials: A
authors.lastname: Amorim
authors.forename: Angel
authors.initials: A
authors.lastname: Carracedo
authors.forename: Antonio
authors.initials: A
authors.lastname: Salas
authors.forename: Eduardo
authors.initials: E
authors.lastname: Raimondi
mesh_terms: D001118:Argentina; D016172:DNA Fingerprinting / Q000379:methods*; D019992:Databases as Topic; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D014505:Urban Population