title: The shape of the epiglottis reflects improvement in upper airway obstruction after weight loss.
abstract: Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent episodes of closure of the upper airway during sleep, and is highly prevalent among overweight individuals. A significant percentage of patients with OSA remain undiagnosed. This condition creates chronic nighttime hypoxemia that can result in significant complications including systemic and pulmonary hypertension, cor pulmonale, and stroke. Polysomnography is still the most widely used method for diagnosing OSA. Studies have shown that in the majority of patients with OSA the airway obstruction involves the retroglossal region. Upon performing esophagogastroduodenoscopy on patients with a wide range of body mass indices (from 21 to 63), we noticed a gradual increase in the concavity of the posterior epiglottal surface as the BMI increases. Upon following some of the patients who underwent laparoscopic gastric banding and lost significant weight, we noticed a dramatic change in the shape of the epiglottis. This reflects a relief in the pressure on the epiglottis created by the collapsing airways in periods of apnea. Thus, the deformity in the shape of the epiglottis reflects the chronic airway collapse in obese patients, and improvement in this deformity after weight loss indicates a relief of the chronic upper airway obstruction.
authors.affiliation: Department of Surgery, North Oakland Medical Centers/Wayne State University, Pontiac, MI, USA.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Gazayerli
authors.forename: Wissam
authors.initials: W
authors.lastname: Bleibel
authors.forename: Ali
authors.initials: A
authors.lastname: Elhorr
authors.forename: Ehab
authors.initials: E
authors.lastname: Elakkary
mesh_terms: D004825:Epiglottis / Q000033:anatomy & histology*; D006801:Humans; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000517:prevention & control*; D015431:Weight Loss