title: Endovascular stent-grafts treatment in acute aortic dissection (type B): clinical outcomes during early, late, or chronic phases.
abstract: OBJECTIVE
  This is a prospective study to evaluate the clinical outcomes of endovascular repair in patients with different phases of type B aortic dissection.
  
  
  BACKGROUND
  Endovascular repairing with stent-grafts is an innovative technique for type B acute aortic dissection. There is no previous study regarding outcomes in different time phases.
  
  
  METHODS
  Sixty-two patients underwent endovascular stent-grafts. There were 23 in the early phase (<24 hr), 20 in the late phase (>or=24 hr to 2 weeks), and 19 in the chronic phase (>2 weeks).
  
  
  RESULTS
  The early phase group had the lowest ratio of stent-grafts to patient and the shortest stent-graft length. The chronic phase group had the largest diameter of false lumen. The technical success rate was 100%; no patient died within hospital. Three patients died within 30 days, with the same death rate in every group. Compared with acute patients, the chronic group had a higher volume of contrast, a higher creatinine post-procedure, and a higher incidence of contrast-induced nephropathy. Multiple regression analysis demonstrated that creatinine and endoleak were independent factors in predicting late death (95% CI, 3.4-26%, P < 0.01). The overall cardiovascular event-free survival was 88.9% +/- 2.1% at 30 days, 87.2% +/- 4.1% at 1 year, and 81.4% +/- 6.3% at 2 years. CT angiography identified the complete or partial thrombosis of the false lumen to be 95.7%.
  
  
  CONCLUSIONS
  Endovascular repairing with stent-graft is safe, feasible, and able to treat type B aortic dissection in all phases. However, chronic renal dysfunction was an independent factor which contributed to a lower survival rate of chronic phase patients.
authors.affiliation: Department of Cardiology, Nanjing First Hospital of Nanjing Medical University, Nanjing, China. chmengx@126.com
authors.forename: Shaoliang
authors.initials: S
authors.lastname: Chen
authors.forename: Fei
authors.initials: F
authors.lastname: Yei
authors.forename: Ling
authors.initials: L
authors.lastname: Zhou
authors.forename: Jun
authors.initials: J
authors.lastname: Luo
authors.forename: Junjie
authors.initials: J
authors.lastname: Zhang
authors.forename: Shoujie
authors.initials: S
authors.lastname: Shan
authors.forename: Nailiang
authors.initials: N
authors.lastname: Tian
authors.forename: Tak W
authors.initials: TW
authors.lastname: Kwan
mesh_terms: D000208:Acute Disease; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D015607:Stents; D016896:Treatment Outcome