title: Biofilm formation by Bacillus cereus is influenced by PlcR, a pleiotropic regulator.
abstract: The DeltaplcR mutant of Bacillus cereus strain ATCC 14579 developed significantly more biofilm than the wild type and produced increased amounts of biosurfactant. Biosurfactant production is required for biofilm formation and may be directly or indirectly repressed by PlcR, a pleiotropic regulator. Coating polystyrene plates with surfactin, a biosurfactant from Bacillus subtilis, rescued the deficiency in biofilm formation by the wild type.
authors.affiliation: Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin, 1925 Willow Dr., Madison, WI 53706, USA.
authors.forename: Yi-Huang
authors.initials: YH
authors.lastname: Hsueh
authors.forename: Eileen B
authors.initials: EB
authors.lastname: Somers
authors.forename: Didier
authors.initials: D
authors.lastname: Lereclus
authors.forename: Amy C Lee
authors.initials: AC
authors.lastname: Wong
mesh_terms: D001409:Bacillus cereus / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001431:Bacteriological Techniques; D018441:Biofilms / Q000254:growth & development*; D003470:Culture Media; D015964:Gene Expression Regulation, Bacterial; D013501:Surface-Active Agents / Q000378:metabolism; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; C099480:PlcR protein, Bacillus; D013501:Surface-Active Agents; D015534:Trans-Activators