title: Incidence trends of prostate cancer in East Anglia, before and during the era of PSA diagnostic testing.
abstract: We investigated prostate cancer incidence in East Anglia from 1971 to 2000. Using age-period-cohort modelling, the number of cases expected in 1991-2000, based on pre-PSA trends, 1971-1990, was compared with that observed. Based on pre-1991 trends, 9203 new cases were expected in 1991-2000, but 9788 cases were observed, an excess of 6%.
authors.affiliation: Department of Public Health and Primary Care, Institute of Public Health, University Forvie Site, Cambridge, CB2 2SR, UK. np275@medschl.cam.ac.uk
authors.forename: N
authors.initials: N
authors.lastname: Pashayan
authors.forename: J
authors.initials: J
authors.lastname: Powles
authors.forename: C
authors.initials: C
authors.lastname: Brown
authors.forename: S W
authors.initials: SW
authors.lastname: Duffy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D004739:England / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology*; D012042:Registries; D012307:Risk Factors
chemical_list: D017430:Prostate-Specific Antigen