title: Low prevalence of prior streptococcus pneumoniae vaccination among potential lung transplant candidates.
abstract: BACKGROUND
  Appropriate vaccination status in the pre-solid organ transplant period is critically important.
  
  
  METHODS
  To determine if lung transplant candidates are adequately vaccinated for Streptococcus pneumoniae, a cross-sectional study was performed. Electronic records of patients referred to our institution for transplantation evaluation between July 2002 and January 2004 were reviewed.
  
  
  RESULTS
  Only 98 of 157 patients (62.4%; 95% confidence interval [CI], 54.8 to 70.1%) evaluated for lung transplantation reported prior receipt of S pneumoniae vaccine. COPD was the only factor significantly associated with vaccination. Patients with COPD were more likely to have received vaccination compared to patients with other diagnoses (odds ratio, 4.66; 95% CI, 2.26 to 9.60).
  
  
  CONCLUSIONS
  S pneumoniae vaccination rates among potential lung transplant candidates fall substantially short of current recommendations for universal immunization. Transplant programs should thoroughly review vaccination status and develop strategies to ensure that candidates receive all appropriate vaccines before transplantation.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, 502 Johnson Pavillion, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. leanne.gasink@uphs.upenn.edu
authors.forename: Leanne B
authors.initials: LB
authors.lastname: Gasink
authors.forename: Alysse G
authors.initials: AG
authors.lastname: Wurcell
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kotloff
authors.forename: Ebbing
authors.initials: E
authors.lastname: Lautenbach
authors.forename: Emily A
authors.initials: EA
authors.lastname: Blumberg
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care / Q000706:statistics & numerical data*; D015995:Prevalence; D022541:Streptococcal Vaccines / Q000008:administration & dosage*; D013296:Streptococcus pneumoniae / Q000276:immunology*; D014181:Transplantation Immunology
chemical_list: D022541:Streptococcal Vaccines