title: [Topology of chromosomes in male gametes. Part 2].
abstract: The article provides a summary of the present knowledge on the organization and chromatin structure in the nucleus of the human sperm cell. The study also presents views and hypotheses on the defined, non-random localization of chromosomes in the sperm nucleus. The individual chromosome territories constitute the central element of the intranuclear architecture. Within these territories, the chromosomes take on the configuration of "hairpin" extendines, with their centromeres towards the interior of the sperm nucleus and the telomeres directed towards the periphery. The functional purpose of this specific topology remains to be explained.
authors.affiliation: Instytut Genetyki Człowieka Polskiej Akademii Nauk w Poznaniu.
authors.forename: Ewa
authors.initials: E
authors.lastname: Wiland
authors.forename: Marta
authors.initials: M
authors.lastname: Zegało
authors.forename: Maciej
authors.initials: M
authors.lastname: Kurpisz
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000000981:diagnostic imaging* / Q000235:genetics*; D002503:Centromere; D002843:Chromatin / Q000737:chemistry; D006657:Histones / Q000145:classification / Q000378:metabolism; D006801:Humans; D008297:Male; D008958:Models, Molecular; D020161:Physical Chromosome Mapping; D011479:Protamines / Q000378:metabolism; D013094:Spermatozoa / Q000166:cytology* / Q000502:physiology; D016615:Telomere; D014463:Ultrasonography
chemical_list: D002843:Chromatin; D006657:Histones; D011479:Protamines