title: Immunolocalization of gastrin-releasing peptide (GRP) in the uteroplacenta of the mouse deer.
abstract: The considerable phylogenetical differences between mouse deer and other ruminants have been established by means of DNA sequence analysis and anatomical observations. To clarify the physiological role of the uteroplacenta of the mouse deer, immunohistochemical observation was attempted by using GRP, which has been suggested as a novel regulatory peptide in the female reproductive tract, as an indicator to compare with other ruminants. Strong positive reactions for the GRP were detected in the uterine glands of the pregnant animals, but not in the non-pregnant ones. Although the placenta of the mouse deer is categorized as a diffuse placenta that is different from other ruminants' polycotyledonary placenta, in terms of GRP immunoreactivity, the mouse deer placenta can be classified as a synepithecholial placenta like the other ruminants'. The secretion of GRP from the uterine glands is of some importance to the fetus in the mouse deer.
authors.affiliation: College of Bioresource Sciences, Nihon University, Kanagawa, Japan. kimura@brs.nihon-u.ac.jp
authors.forename: J
authors.initials: J
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Budipitojo
authors.forename: M
authors.initials: M
authors.lastname: Sasaki
authors.forename: N
authors.initials: N
authors.lastname: Kitamura
authors.forename: J
authors.initials: J
authors.lastname: Yamada
authors.forename: H
authors.initials: H
authors.lastname: Endo
authors.forename: K
authors.initials: K
authors.lastname: Fukuta
mesh_terms: D000818:Animals; D005260:Female; D019886:Gastrin-Releasing Peptide / Q000032:analysis* / Q000276:immunology; D007150:Immunohistochemistry / Q000379:methods / Q000662:veterinary; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D012418:Ruminants / Q000378:metabolism*; D013045:Species Specificity; D014599:Uterus / Q000378:metabolism*
chemical_list: D019886:Gastrin-Releasing Peptide