title: Gitelman syndrome: report of three cases and literature review.
abstract: Gitelman syndrome (GS) is a rare autosomal recessive, inherited renal tubular disorder. Herein, we report three cases of GS, one sporadic case and two siblings. They have typical laboratory findings, including hypokalemia, metabolic alkalosis, hypomagnesemia, and hypocalciuria. All of them were treated with oral potassium and magnesium supplements. They received regular pediatric clinic follow-up to check electrolytes and monitor development. These three cases reminded us that doctors should be alert to unexplained hypokalemia, which is usually the initial presentation of GS.
authors.affiliation: Department of Pediatrics, Kaohsiung Municipal Hsiao-Kang Hospital, Taiwan.
authors.forename: Ya-Ting
authors.initials: YT
authors.lastname: Lee
authors.forename: I-Fan
authors.initials: IF
authors.lastname: Wang
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Lin
authors.forename: Chia-Tsuan
authors.initials: CT
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000471:Alkalosis / Q000628:therapy*; D002118:Calcium / Q000652:urine*; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000628:therapy*; D008274:Magnesium / Q000627:therapeutic use; D008275:Magnesium Deficiency / Q000628:therapy*; D008297:Male; D011189:Potassium Chloride / Q000627:therapeutic use; D015499:Renal Tubular Transport, Inborn Errors / Q000628:therapy*; D049992:Sodium Chloride Symporters / Q000235:genetics; D013577:Syndrome
chemical_list: D049992:Sodium Chloride Symporters; D011189:Potassium Chloride; D008274:Magnesium; D002118:Calcium