Bronchogenic carcinoma of squamous cells in a young pregnant woman.
Lung cancer continues to be the most incident neoplasia in the world and also the most frequent cause of death by cancer, with more than 900000 new cases per year. Women present greater risk of developing bronchogenic carcinoma, possibly because of differences in metabolism of the carcinogens associated with tobacco and also because of hormonal differences because estrogens can promote the appearance of lung cancer, including during pregnancy. We have described the case of a 25-year-old patient who developed squamous cell carcinoma of the lung during her third pregnancy, with a progressive worsening of her general condition and progression until death. We believe that the pregnancy could have contributed to the evolution of the disease, especially because of the increased levels of gestational hormones, particularly the estrogen, because its receptors have an important role in regulating growth and in the differentiation of several tissues facilitating like this, the development of the neoplasia, and complicating its early diagnosis.
Penha
Daniel Silva Gontijo
DS
General Pathology Division, Biological Science Department, Triângulo Mineiro Medical School, Uberaba, MG 38025-180, Brazil. 99danielsilva@bol.com.br
Salge
Ana Karina Marques
AK
Tironi
Fábio
F
Saldanha
João Carlos
JC
Castro
Eumenia Costa da Cunha
EC
Teixeira
Vicente de Paula Antunes
Vde P
dos Reis
Marlene Antônia
MA
D000328:Adult; D002283:Carcinoma, Bronchogenic / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*