Fertility sparing options for breast cancer patients.
BACKGROUND
Breast cancer is the most common malignancy to affect women of reproductive age. As more women are delaying fertility into the 4th and 5th decade of life, more women face the possibility of a breast cancer diagnosis prior to accomplishing their reproductive goals.


METHODS
Literature review PubMed, EMBASE.


CONCLUSIONS
From expectant management, hormonal suppression, in vitro fertilization with embryo freezing, to egg and ovarian tissue cryopreservation, numerous fertility sparing options are available to women with breast cancer. Therapy will be individualized based on a patient's age, financial resources, availability of services, cancer prognosis, ER/PR receptor, HER2 and BRCA status.
Murray
Ringland S
RS
101 Manning Drive, CB 7570, University of North Carolina, Chapel Hill, 27759, USA. ringland_murray@med.unc.edu
D001943:Breast Neoplasms / Q000235:genetics / Q000401:mortality / Q000503:physiopathology*; D015925:Cryopreservation; D005260:Female; D005298:Fertility / Q000187:drug effects / Q000528:radiation effects; D005307:Fertilization in Vitro; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists / Q000037:antagonists & inhibitors; D006801:Humans; D011379:Prognosis; D014019:Tissue Donors
D007987:Gonadotropin-Releasing Hormone