[Constrictive pericarditis caused by carbergoline].
A 72-year-old male with paralysis agitans presented with symptoms and findings of constrictive pericarditis (CP). One year prior, he had a minor lateral MI. The patient had been treated with cabergoline for four years. At pericardiectomy, a thickened pericardium of 1-1,5 cm encased the right side of the heart. The pericardium was normal in the infarction area. Dopamine agonists pergolide and cabergoline for treatment of Parkinson s disease have been associated with development of CP. The absence of pericardial thickening in the infarction area suggests cabergoline as a probable cause.
Hjortshøj
Søren Pihlkjaer
SP
Arhus Universitetshospital, Aalborg Sygehus, Kardiovaskulaert Forskningscenter, Kardiologisk Afdeling S, DK-9100 Aalborg. sph@dadlnet.dk
Poulsen
Steen Hvitfeldt
SH
Andreasen
Jan Jesper
JJ
D000368:Aged; D000978:Antiparkinson Agents / Q000009:adverse effects*; D000077465:Cabergoline; D015259:Dopamine Agents / Q000009:adverse effects*; D004873:Ergolines / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010494:Pericarditis, Constrictive / Q000139:chemically induced*
D000978:Antiparkinson Agents; D015259:Dopamine Agents; D004873:Ergolines; D000077465:Cabergoline