title: Pyrrolizidine alkaloid level in Senecio bicolor (Wilid.) Tod, ssp. cineraria (DC.) from middle Europe.
abstract: From Senecio bicolor, ssp. cineraria, cultivated in middle Europe, seven pyrrolizidine alkaloids (PA) were isolated and their structures elucidated by spectroscopical methods. Besides the already known senecionine, integerrimine, seneciphylline, jacobine, jacoline and jaconine the jacobine-acetate was found. On account of structure toxicity relationship all PA show toxic side-effects.
authors.affiliation: Pharmazeutisches Institut der Universität, Bonn, Germany. wiedenfeld@uni-bonn.de
authors.forename: H
authors.initials: H
authors.lastname: Wiedenfeld
authors.forename: C
authors.initials: C
authors.lastname: Montes
authors.forename: B
authors.initials: B
authors.lastname: Tawil
authors.forename: A
authors.initials: A
authors.lastname: Contin
authors.forename: R
authors.initials: R
authors.lastname: Wynsma
mesh_terms: D005060:Europe; D008401:Gas Chromatography-Mass Spectrometry; D006705:Homeopathy; D009682:Magnetic Resonance Spectroscopy; D011763:Pyrrolizidine Alkaloids / Q000032:analysis* / Q000633:toxicity; D012674:Senecio / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D011763:Pyrrolizidine Alkaloids