"Clickphine": a novel and highly versatile P,N ligand class via click chemistry.
[Structure: see text] A novel P,N-type ligand family (ClickPhine) is disclosed that is easily accessible using the Cu(I)-catalyzed azide-alkyne "click" cycloaddition. A diverse set of ligands was made in just three steps from readily available starting materials to give several homogeneous and a heterogeneous catalyst. Preliminary experiments show the efficacy of these ligands in the Pd-catalyzed allylic alkylation reaction.
Detz
Remko J
RJ
Van't Hoff Institute for Molecular Sciences, Faculty of Science, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands.
Heras
Silvia Arévalo
SA
de Gelder
R
R
van Leeuwen
Piet W N M
PW
Hiemstra
Henk
H
Reek
Joost N H
JN
van Maarseveen
Jan H
JH