title: Ineffective peripheral tissue perfusion: Clinical validation in patients with hypertensive cardiomiopathy.
abstract: OBJECTIVE
  To validate defining characteristics of ineffective peripheral tissue perfusion using vasomotor function assessment.
  
  
  METHODS
  Twenty-four patients with hypertensive cardiomiopathy were evaluated for 18 defining characteristics of ineffective peripheral tissue perfusion and underwent vasomotor function assessment with induction of reactive hyperemia, intra-arterial infusion of acetylcholine, and pulse wave velocity measurement. The Student's t test and Kruskall-Wallis test were used to assess the significance of relationships between defining characteristics and vasomotor function data.
  
  
  RESULTS
  Diminished lower extremity pulses were associated with diminished forearm blood flow during acetylcholine infusion; left ventricular overload, intermittent claudication, and diminished skin moisture were associated with elevated pulse wave velocity values.
  
  
  CONCLUSIONS
  The defining characteristics of ineffective peripheral tissue perfusion were highly associated with vasomotor function data as "gold standards" for that diagnosis.
  
  
  CONCLUSIONS
  Nurses should be able to accurately assess diminished lower extremity pulses, intermittent claudication, and diminished skin moisture as relevant characteristics of ineffective peripheral tissue perfusion in patients with hypertensive cardiomiopathy.
authors.affiliation: Nursing of Educational Service, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil. rcgsilva@ig.com.br
authors.forename: Rita de Cassia
authors.initials: Rde C
authors.lastname: Gengo de Silva
authors.forename: Diná de Almeida Lopes
authors.initials: Dde A
authors.lastname: Monteiro da Cruz
authors.forename: Luiz Aparecido
authors.initials: LA
authors.lastname: Bortolotto
authors.forename: Maria Claudia
authors.initials: MC
authors.lastname: Costa Irigoyen
authors.forename: Eduardo
authors.initials: E
authors.lastname: Moacyr Krieger
authors.forename: Jurema da Silva
authors.initials: Jda S
authors.lastname: Herbas Palomo
authors.forename: Fernanda Marciano
authors.initials: FM
authors.lastname: Consolim-Colombo
mesh_terms: D000109:Acetylcholine; D001783:Blood Flow Velocity; D009202:Cardiomyopathies / Q000150:complications* / Q000188:drug therapy; D015400:Clinical Nursing Research; D005260:Female; D006333:Heart Failure / Q000150:complications; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D007383:Intermittent Claudication / Q000209:etiology; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009730:Nursing Assessment / Q000379:methods / Q000592:standards*; D009733:Nursing Diagnosis / Q000379:methods / Q000592:standards*; D015403:Nursing Evaluation Research; D016491:Peripheral Vascular Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D011674:Pulse; D013318:Stroke Volume; D014665:Vasodilator Agents; D018487:Ventricular Dysfunction, Left / Q000150:complications
chemical_list: D014665:Vasodilator Agents; D000109:Acetylcholine