Simple synthesis of enantiomerically pure sauriols A and B.
Sauriols A and B belong to a class of diarylbutane-lignans and exhibit antifeedant activity. We succeeded in the first synthesis of sauriols A and B by using a simple and efficient asymmetric dimerization of a cinnamic acid derivative as the key step.
Mori
Naoki
N
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Watanabe
Hidenori
H
Kitahara
Takeshi
T
D002934:Cinnamates / Q000737:chemistry*; D019281:Dimerization; D017705:Lignans / Q000138:chemical synthesis*; D013237:Stereoisomerism
D002934:Cinnamates; D017705:Lignans; C514378:sauriol A; C514379:sauriol B; C029010:cinnamic acid