title: [Typical and atypical features of focal nodular hyperplasia of the liver on helical CT images].
abstract: OBJECTIVE
  Focal nodular hyperplasia (FNH) is a rare hepatic neoplastic lesion. This study was to evaluate the typical and atypical features of FNH of the liver on helical computed tomography (CT) images to improve the diagnosis accuracy.
  
  
  METHODS
  Helical CT images of 32 patients with 37 lesions were reviewed in Cancer Center, Sun Yat-sen University retrospectively, who were confirmed as FNH by histopathologic or clinic examinations. The number, size, margin status, density, enhancing type, presence of a center scar, and presence of a pseudocapsule of FNH lesions were analyzed.
  
  
  RESULTS
  The largest diameters of 14 lesions were < or = 3 cm, of 23 lesions were > 3 cm; 20 lesions were subcapsular; pseudocapsule was presented in 7 lesions with the largest diameters of > 3 cm; 22 lesions had center scars, among them, the largest diameters of 20 lesions was > 3 cm. All lesions were hyperattenuated to the liver in hepatic arterial phase; 31 lesions were enhanced homogeneously in hepatic arterial phase; abnormally thickened vessels were presented at the border of 17 lesions.
  
  
  CONCLUSIONS
  Typical helical CT features of FNH include homogeneous enhancement in hepatic arterial phase, presence of central scar, and delayed enhancement. Atypical helical CT features of FNH include heterogeneous enhancement in hepatic arterial phase, absence of central scar, and presence of pseudocapsule. The various CT features are related to the pathologic type and the largest diameter of the lesion.
authors.affiliation: State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China. zhenglie0791@tom.com
authors.forename: Lie
authors.initials: L
authors.lastname: Zheng
authors.forename: Pei-Hong
authors.initials: PH
authors.lastname: Wu
authors.forename: Jing-Xian
authors.initials: JX
authors.lastname: Shen
authors.forename: Yun-Xian
authors.initials: YX
authors.lastname: Mo
authors.forename: Chuan-Miao
authors.initials: CM
authors.lastname: Xie
authors.forename: Chao-Mei
authors.initials: CM
authors.lastname: Ruan
authors.forename: Li
authors.initials: L
authors.lastname: Li
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging; D000293:Adolescent; D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D036542:Tomography, Spiral Computed / Q000379:methods*; D055815:Young Adult