title: Chemical studies on the constituents of the chinese medicinal herb Euphorbia helioscopia L.
abstract: Euphoheliosnoid D (1), a new jatrophone-type diterpenoid, was isolated together with 22 known metabolites from the Chinese medicinal herb Euphorbia helioscopia L. The structure and relative stereochemistry of 1 was elucidated on the basis of spectroscopic methods. Compounds 14-23 were obtained from the species for the first time while compound 14, 2alpha-hydroxy helioscopinolide B, was isolated as a new natural product.
authors.affiliation: State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Zu Chong Zhi Rd. 555, Zhangjiang Hi-Tech park, Shanghai 201203, PR China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Yue-Wei
authors.initials: YW
authors.lastname: Guo
mesh_terms: D004224:Diterpenes / Q000032:analysis* / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D028481:Euphorbia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C513806:euphoheliosnoid D