[Diagnostic criteria of neurosarcoidosis].
We have collaborated with Japanese Sarcoidosis Society and Japanese Society of Respiratory Disease to provide a new diagnostic criteria of neurosarcoidosis. At least two of six examinations are important. These include bilateral hilar lymphadenopathy, abnormal uptake of 67Ga scintigraphy, broncho alveolar lavage fluid examination, elevated serum ACE, negative tuberculin reaction, and elevated serum or urinary calcium level. (definite) Having positive clinical findings which suggest a neurosarcoidosis. Pathology proven case. (probable) Having positive clinical findings which suggest a neurosarcoidosis. Pathology proven in other organ. At least two of six examinations are positive. (possible) Having positive clinical findings which suggest a neurosarcoidosis. At least two of six examinations are positive. CNS sarcoidosis, sarcoid neuroopathy and sarcoid myopathy are separately diagnosed. Kveim reaction which is time consuming, not so specific, and difficult to obtain its antigen is no more necessary.
Sakuta
Manabu
M
Department of Neurology, Kyorin University.
Kumamoto
Toshihide
T
Iizuka
Takahiro
T
Nishiyama
Kazutoshi
K
Oritsu
Masaru
M
D002493:Central Nervous System Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis; D012507:Sarcoidosis / Q000175:diagnosis*