HPLC determination of papaveraldine and papaverinol in papaverine injection.
A simple, specific, and sensitive high-performance liquid chromatographic method for the determination of papaveraldine and papaverinol in papaverine hydrochloride injection has been developed. The compounds were chromatographed on a reversed-phase C-18 column using a water-methanol-acetonitrile solvent system containing sodium lauryl sulphate ion-pair reagent.
Colautti
A
A
Istituto di Chimica Farmaceutica and Tossicologica, Università di Trieste, 34137 Trieste, Italy.
Fontani
F
F
Maurich
V
V