[Inflammation is a key effector phase in immune reactions].
Inflammation is key element in effector phase of all immune processes and create a cascade system of specific enzyme functions regulated in autocrine way. Humoral antigen-antibody reaction activate the complement system which is responsible for secondary mediatots generation and tissues destruction. Liberated mediators like kinins, leukotriens inflammatory cytokines and activated cell bound metalloproteases in tissues and blood vessels are responsible for oedema of tissues, pain, cell destruction and organ dysfunction. Induction of T cell dependent inflammatory reaction involve antigen dependent activation of T cells which usually is delayed and long lasting. The immune reactions responsible for specific activation induce inflammation.
Tchórzewski
Henryk
H
Instytut Centrum Zdrowia Matki Polki w Lodzi, Zakład Immunologii Klinicznej.
D000818:Animals; D000917:Antibody Formation; D006801:Humans; D007111:Immunity, Cellular; D007249:Inflammation / Q000276:immunology*; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000276:immunology