Porokeratosis of Mibelli induced by topical corticosteroid.
BACKGROUND
[corrected] Prorokeratosis of Mibelli is a chronic disorder characterised by slightly atrophic plaques surrounded by keratotic border.


RESULTS
A 45-year-old with clobetazole propionate ointment for psoriasis over 15 years developed characteristic lesions of porokeratosis Mibelli on the elbows. Histopathological examination revealed the cornoid lamellae located on the edges of the specimen and psoriasiform acanthosis and a spongiotic pustule formation in the center of the specimen; thus, it was suggested as 'psoriasis encircled by porokeratosis'.


CONCLUSIONS
Development of porokeratosis may be explained by the local immunosuppressive effect of the prolonged application of the topical steroid.
Yazkan
Figen
F
Department of Dermatology, Ege University Medical Faculty, Bornova-Izmir, Turkey.
Turk
Bengu Gerceker
BG
Dereli
Tugrul
T
Kazandi
Ali Can
AC
D000052:Acanthosis Nigricans / Q000473:pathology; D017115:Catheter Ablation; D002990:Clobetasol / Q000009:adverse effects*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D017499:Porokeratosis / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D011565:Psoriasis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D016896:Treatment Outcome
D005938:Glucocorticoids; D002990:Clobetasol