title: Notes on human cases of cystic echinococcosis in Peru.
abstract: Cystic echinococcosis (CE) is a high prevalent zoonosis in the central and southern Peruvian Andes. Serum samples (n50)from patients presenting presumptive clinical and radiological diagnosis of CE (group 1), were tested for antibodies against Echinococcus granulosus metacestode using Arc-5 double diffusion assay (DD5), immunoelectrophoresis (IEF), and immunoelectrotransfer blot (EITB) techniques. Serum samples (n18) from patients presenting other parasite infections (paragonomiasis, cysticercosis, and fascioliasis) or healthy blood donors (n15), were designated as control groups. The overall sensitivity of the tests was of 94% (DD5 and IEF tests) or 96% (EITB test). Only patients from group 1 were seropositive for CE. Polypeptides of 21, 31, and 48 kDa were considered positive for CE. Based on these results, this study demonstrates that CE also occurs in other coastal departments (Piura, Ancash, Ica, Arequipa, and Tacna) besides Lima.
authors.affiliation: Departamento de Parasitologia, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: Elizabeth Luz Sanchez
authors.initials: EL
authors.lastname: Romani
authors.forename: Rosângela
authors.initials: R
authors.lastname: Rodrigues-Silva
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Maldonado
authors.forename: José Roberto
authors.initials: JR
authors.lastname: Machado-Silva
authors.forename: Delir Corrêa
authors.initials: DC
authors.lastname: Gomes
mesh_terms: D000293:Adolescent; D000328:Adult; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000276:immunology*; D016022:Case-Control Studies; D002648:Child; D004443:Echinococcosis / Q000175:diagnosis*; D048209:Echinococcus granulosus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D015151:Immunoblotting; D008297:Male; D008875:Middle Aged; D010568:Peru; D012680:Sensitivity and Specificity
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth