title: Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20.
abstract: A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.
authors.affiliation: Oncology Department, Hospital General de Elda, Alicante, Spain. cerveragrau@yahoo.es
authors.forename: J M
authors.initials: JM
authors.lastname: Cervera Grau
authors.forename: G
authors.initials: G
authors.lastname: Galiana Esquerdo
authors.forename: C
authors.initials: C
authors.lastname: Llorca Ferrándiz
authors.forename: H
authors.initials: H
authors.lastname: Briceño García
authors.forename: M
authors.initials: M
authors.lastname: Díaz Castellano
authors.forename: P
authors.initials: P
authors.lastname: Férriz Moreno
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D058846:Antibodies, Monoclonal, Murine-Derived; D018951:Antigens, CD20; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005871:Castleman Disease / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D018023:HIV Seronegativity; D006566:Herpesviridae Infections / Q000150:complications; D019288:Herpesvirus 8, Human; D006801:Humans; D010198:Pancytopenia / Q000150:complications; D012074:Remission Induction; D000069283:Rituximab
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D018951:Antigens, CD20; D000069283:Rituximab