title: Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia.
abstract: BACKGROUND
  This randomized trial examined whether lightweight (LW) polypropylene mesh (large pore size, partially absorbable) could have long-term benefits in reducing chronic pain and inflammation after inguinal hernia repair.
  
  
  METHODS
  Six hundred men with a primary unilateral inguinal hernia were randomized to Lichtenstein repair using a standard polypropylene mesh or a LW mesh in one of six centres. The patients were blinded to which mesh they received. Clinical examination was performed and a pain questionnaire completed 3 years after surgery.
  
  
  RESULTS
  Of the 590 men who had surgery, 243 (82.7 percent) of 294 in the standard mesh group and 251 (84.8 percent) of 296 in the LW mesh group were examined in the clinic, a median of 37 (range 30-48) months after hernia repair. There were nine recurrent hernias in each group (3.7 percent with standard mesh and 3.6 per cent with LW mesh). Patients who had LW mesh had less pain on examination, less pain on rising from lying to sitting, fewer miscellaneous groin problems and felt the mesh less often than patients with standard mesh.
  
  
  CONCLUSIONS
  Use of LW mesh for Lichtenstein hernia repair did not affect recurrence rates, but improved some aspects of pain and discomfort 3 years after surgery.
authors.affiliation: Clintec, Karolinska Institutet, Stockholm, Sweden. sven.bringman@ki.se
authors.forename: S
authors.initials: S
authors.lastname: Bringman
authors.forename: S
authors.initials: S
authors.lastname: Wollert
authors.forename: J
authors.initials: J
authors.lastname: Osterberg
authors.forename: S
authors.initials: S
authors.lastname: Smedberg
authors.forename: H
authors.initials: H
authors.lastname: Granlund
authors.forename: T-J
authors.initials: TJ
authors.lastname: Heikkinen
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011126:Polypropylenes / Q000627:therapeutic use*; D011788:Quality of Life; D012008:Recurrence; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D011126:Polypropylenes