title: Size of corneal topographic effective optical zone: comparison of standard and customized myopic laser in situ keratomileusis.
abstract: OBJECTIVE
  To investigate the corneal topographic effective optical zone (EOZ) in eyes after wavefront-guided myopic laser in situ keratomileusis (LASIK) and to compare them with the EOZ after standard LASIK.
  
  
  METHODS
  Retrospective, case-control study.
  
  
  METHODS
  We evaluated the corneal topographic maps of 41 eyes of 25 consecutive patients who had CustomVue LASIK (CV LASIK) and 41 eyes of 23 patients who had standard LASIK with correction up to -7 diopters using the VISX Star S4 laser (VISX Inc, Santa Clara, California, USA). On the refractive map of the Humphrey Topography System, we defined the EOZ as the area outlined by a change of corneal power of 0.5 diopters from the power at the center of the pupil. We analyzed the differences in EOZs of the two ablation patterns and the correlation between EOZ and magnitude of refractive correction.
  
  
  RESULTS
  The mean postoperative EOZs were 17.9 +/- 3.7 mm(2) and 11.4 +/- 3.4 mm(2) after CV and standard LASIK, representing 60% and 40% of the laser-programmed optical zones, respectively (both P < .0001). There was no correlation between the postoperative EOZs and the magnitude of refractive correction for both ablations (all P > .05). In eyes with spherical correction (cylinder < or =0.25 diopters), CV LASIK increased the preoperative EOZ by 3.8 +/- 5.6 mm(2) (P = .018), whereas standard LASIK decreased EOZ by 4.5 +/- 5.2 mm(2) (P = .005).
  
  
  CONCLUSIONS
  CV LASIK created larger corneal topographic EOZs than standard ablation. In eyes with spherical correction, the preoperative EOZ was expanded by CV LASIK and reduced by standard LASIK.
authors.affiliation: Baylor College of Medicine, Department of Ophthalmology, Houston, Texas 77030, USA.
authors.forename: Louis
authors.initials: L
authors.lastname: Racine
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Douglas D
authors.initials: DD
authors.lastname: Koch
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery; D016022:Case-Control Studies; D003315:Cornea / Q000502:physiology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology* / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies