Extended-donor criteria liver allografts.
Extended-donor criteria liver allografts do not meet traditional criteria for transplantation. Although these organs offer immediate expansion of the donor pool, transplantation of extended-donor criteria liver allografts increases potential short- and long-term risk to the recipient. This risk may manifest as impaired allograft function or donor-transmitted disease. Guidelines defining this category of donor, level of acceptable risk, principles of consent, and post-transplantation surveillance have not been defined. This article reviews the utilization, ethical considerations, and outcomes of extended-donor criteria liver allografts.
Alkofer
Barbara
B
Center for Liver Disease and Transplantation, New York-Presbyterian Hospital, New York, NY 10032, USA.
Samstein
Benjamin
B
Guarrera
James V
JV
Kin
Cindy
C
Jan
Dominique
D
Bellemare
Sarah
S
Kinkhabwala
Milan
M
Brown
Robert
R
Emond
Jean C
JC
Renz
John F
JF
D046148:Donor Selection; D015490:HTLV-I Infections / Q000150:complications / Q000635:transmission; D006509:Hepatitis B / Q000150:complications / Q000635:transmission; D006526:Hepatitis C / Q000150:complications / Q000635:transmission; D006801:Humans; D007258:Informed Consent; D016031:Liver Transplantation; D012720:Severity of Illness Index; D014019:Tissue Donors / Q000600:supply & distribution*; D014850:Waiting Lists