title: Behavioural and emotional problems in very preterm and very low birthweight infants at age 5 years.
abstract: BACKGROUND
  Children born very preterm (VP; <32 weeks' gestation) or with very low birth weight (VLBW, <1500 g; hereafter called VP/VLBW) are at risk for behavioural and emotional problems during school age and adolescence. At school entrance these problems may hamper academic functioning, but evidence on their occurrence at this age in VP/VLBW children is lacking.
  
  
  OBJECTIVE
  To provide information on academic functioning of VP/VLBW children and to examine the association of behavioural and emotional problems with other developmental problems assessed by paediatricians.
  
  
  METHODS
  A cohort of 431 VP/VLBW children aged 5 years (response rate 76.1%) was compared with two large national samples of children of the same age (n = 6007, response rate 86.9%).
  
  
  METHODS
  Behavioural and emotional problems measured by the Child Behavior Checklist (CBCL), and paediatrician assessment of other developmental domains among VP/VLBW children.
  
  
  RESULTS
  The prevalence rate of a CBCL total problems score in the clinical range was higher among VP/VLBW children than among children of the same age from the general population (13.2% v 8.7%, odds ratio 1.60 (95% confidence interval 1.18 to 2.17)). Mean differences were largest for social and attention problems. Moreover, they were larger in children with paediatrician-diagnosed developmental problems at 5 years, and somewhat larger in children with severe perinatal problems.
  
  
  CONCLUSIONS
  At school entrance, VP/VLBW children are more likely to have behavioural and emotional problems that are detrimental for academic functioning. Targeted and timely help is needed to support them and their parents in overcoming these problems and in enabling them to be socially successful.
authors.affiliation: Department of Child Health, TNO (Netherlands Organization of Applied Scientific Research) Quality of Life, Leiden, The Netherlands. S.A.Reijneveld@med.umcg.nl
authors.forename: S A
authors.initials: SA
authors.lastname: Reijneveld
authors.forename: M J K
authors.initials: MJ
authors.lastname: de Kleine
authors.forename: A L
authors.initials: AL
authors.lastname: van Baar
authors.forename: L A A
authors.initials: LA
authors.lastname: Kollée
authors.forename: C M
authors.initials: CM
authors.lastname: Verhaak
authors.forename: F C
authors.initials: FC
authors.lastname: Verhulst
authors.forename: S P
authors.initials: SP
authors.lastname: Verloove-Vanhorick
mesh_terms: D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology*; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000523:psychology*; D019102:Infant, Very Low Birth Weight / Q000523:psychology*; D008297:Male; D019964:Mood Disorders / Q000209:etiology*; D012307:Risk Factors