title: Protein-mediated fatty acid uptake: novel insights from in vivo models.
abstract: Long-chain fatty acids are both important metabolites as well as signaling molecules. Fatty acid transport proteins are key mediators of cellular fatty acid uptake and recent transgenic and knockout animal models have provided new insights into their contribution to energy homeostasis and to pathological processes, including obesity and insulin desensitization.
authors.affiliation: Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA.
authors.forename: Holger
authors.initials: H
authors.lastname: Doege
authors.forename: Andreas
authors.initials: A
authors.lastname: Stahl
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D001692:Biological Transport / Q000502:physiology; D050612:Fatty Acid Transport Proteins / Q000235:genetics / Q000502:physiology*; D005227:Fatty Acids / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D051379:Mice; D018345:Mice, Knockout; D023421:Models, Animal; D009765:Obesity / Q000503:physiopathology; D011110:Polymorphism, Genetic / Q000235:genetics; D015398:Signal Transduction / Q000502:physiology
chemical_list: D050612:Fatty Acid Transport Proteins; D005227:Fatty Acids