Persistence of antimicrobial effect of antiseptics in surgical hand hygiene regimens.
OBJECTIVE
To determine the persistence of antimicrobial effect of antiseptic solutions used in surgical hand hygiene procedure, and the in-house preparation was compared to the commercial solution for its efficacy.


METHODS
The present study was performed in a 150-bed hospital involving 19 staff from general, orthopedics, KUB, and OB-GYN surgical teams in 48 operations. The antimicrobial effects from 4 different solutions were determined and compared.


RESULTS
The study showed that the commercial alcohol-based antiseptic solution was equally or more effective than long-time accepted povidone-iodine or chlorhexidine gluconate solutions and had better persistent effect. The in-house preparation was effective comparable to the commercial solution.


CONCLUSIONS
The commercial alcohol-based antiseptic solution had better persistence of antimicrobial effects compared to the in-house alcohol-based hand rub, povidone iodine and chlorhexidine gluconate.
Noparat
Wilai
W
Camillion Hospital, Bangkok.
Siripanichakorn
Kanokrat
K
Tribuddharat
Chanwit
C
Danchaivijitr
Somwang
S
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005782:Gels; D006225:Hand / Q000382:microbiology*; D006235:Hand Disinfection; D006801:Humans; D006920:Hygiene; D008297:Male; D011206:Povidone-Iodine / Q000494:pharmacology*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013995:Time
D000891:Anti-Infective Agents, Local; D005782:Gels; D000431:Ethanol; D011206:Povidone-Iodine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine