Electron-impact mass spectrometry of diuretic agents.
The mass spectrometric behaviour of nineteen diuretic agents in clinical use under conditions of 70 eV electron impact is analysed from reported and novel mass spectra. The molecular compositions of fragment ions are supported by high resolution data in selected cases, and a scheme presented for the rapid identification by MS of diuretics within the group.
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School of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK.