title: Reconstruction of musculoskeletal defects following oncologic resection in 76 patients.
abstract: Between 1990 and 2002, 76 patients underwent 102 muscle flap reconstructions for extremity sarcomas. The patients had radical resection with immediate reconstruction. Reconstructions were performed by the Musculoskeletal Oncology and Plastic Surgery services. The mean age of our patients was 39.1 years. Patients were studied for a mean of 25.4 months. There were 79 pedicle flaps and 23 free flaps. Complications occurred in 23.7% of patients, including wound necroses, seromas, postoperative bleeding, postoperative infections, and flap loss. Five patients required a secondary flap procedure. The overall flap survival rate was 98%. Three patients had local recurrences. Sixteen patients (21.1%) have died of their disease. Five patients are alive with metastases. In 54 patients, Musculoskeletal Tumor Society (MSTS) functional evaluation scores averaged 27.1 (range, 12-30). In this large series of patients, we have demonstrated that, although minor complications are common, functional limbs can be salvaged following oncologic resection from the extremities.
authors.affiliation: Department of Surgery, Division of Plastic Surgery, New Jersey Medical School, UMDNJ, Newark, NJ, USA.
authors.forename: Erik
authors.initials: E
authors.lastname: Hoy
authors.forename: Mark
authors.initials: M
authors.lastname: Granick
authors.forename: Joseph
authors.initials: J
authors.lastname: Benevenia
authors.forename: Francis
authors.initials: F
authors.lastname: Patterson
authors.forename: Ramazi
authors.initials: R
authors.lastname: Datiashvili
authors.forename: Brian
authors.initials: B
authors.lastname: Bille
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007866:Leg; D007867:Leg Bones; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D012509:Sarcoma / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000601:surgery*; D013524:Surgical Flaps