title: Determination of furosemide in rat plasma using HPLC and liquid scintillation.
abstract: A rapid and convenient HPLC method for the determination of furosemide in plasma is described. The method uses a buffered mobile phase containing 22% (v/v) acetonitrile. The precision, detection limit and the correlation between the HPLC method and a liquid scintillation determination of furosemide are satisfactory. A pharmacokinetic study of furosemide in the rat is described.
authors.affiliation: Institute de Chimie, USTHB, B.P. no. 9, Dar-El-Beida, Alger, Algeria.
authors.forename: S
authors.initials: S
authors.lastname: Guermouche
authors.forename: M H
authors.initials: MH
authors.lastname: Guermouche
authors.forename: M
authors.initials: M
authors.lastname: Mansouri
authors.forename: L
authors.initials: L
authors.lastname: Abed