Treatment of severe osteoporosis with alendronate in a patient with lysinuric protein intolerance.
Lysinuric protein intolerance is an inborn error of cationic amino acid transport of which osteoporosis is a major feature. Treatment with oral bisphosphonates improves bone mineral density even in severe osteoporosis.
Gömez
L
L
Unidad de Enfermedades Metabólicas, Hospital Sant Joan de Déu, Barcelona, Spain. lgomez@hsjdbcn.org
García-Cazorla
A
A
Gutiérrez
A
A
Artuch
R
R
Varea
V
V
Martín
J
J
Pinillos
S
S
Vilaseca
M A
MA
D019386:Alendronate / Q000494:pharmacology*; D000592:Amino Acid Metabolism, Inborn Errors / Q000150:complications* / Q000628:therapy*; D050071:Bone Density Conservation Agents / Q000494:pharmacology; D006801:Humans; D008239:Lysine / Q000737:chemistry*; D010024:Osteoporosis / Q000150:complications* / Q000628:therapy*
D050071:Bone Density Conservation Agents; D008239:Lysine; D019386:Alendronate