title: Automated hepatic volumetry for living related liver transplantation at multisection CT.
abstract: OBJECTIVE
  To prospectively compare in vivo hepatic automated volumetry with manual volumetry and measured liver volume.
  
  
  METHODS
  The study was conducted in accordance with the guidelines of the Institutional Review Board of Kumamoto University (Japan). Patient informed consent was obtained. Preoperative multisection computed tomography (CT) was performed in 35 consecutive patients (21 men, 14 women; mean age, 42.8 years; range, 28-72 years) with hepatic disease awaiting living related liver transplantation. The CT scans covered the entire liver at a section thickness of 2.5 mm. Liver volume was estimated by using both the automated and the manual methods. Actual liver weight was obtained for all patients and was converted to hepatic volume on the basis of a predetermined relationship between actual liver weight and volume. Processing time required for both methods was also recorded. Two-tailed paired t test, correlation coefficient, and Bland-Altman tests were used for statistical analyses.
  
  
  RESULTS
  Mean liver weight was 881.7 g +/- 249.8 (standard deviation), and mean measured liver volume was 956.00 cm(3) +/- 280.10. Volumetry performed with the automated and manual methods provided liver volumes of 982.99 cm(3) +/- 301.98 and 937.10 cm(3) +/- 301.31, respectively. There was good correlation between measured and estimated volumes obtained with the automated method (r = 0.792, P < .01). The manual and automated methods required 32.8 minutes +/- 6.9 and 4.4 minutes +/- 1.9, respectively.
  
  
  CONCLUSIONS
  The automated method reduced the time required for volumetry of the liver and provided acceptable measurements.
authors.affiliation: Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto City, Kumamoto, 860-8556, Japan. yosiharu156@lilly.ocn.ne.jp
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Nakayama
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.forename: Shigehiko
authors.initials: S
authors.lastname: Katsuragawa
authors.forename: Ryuji
authors.initials: R
authors.lastname: Ikeda
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hiai
authors.forename: Kazuo
authors.initials: K
authors.lastname: Awai
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kusunoki
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Hideaki
authors.initials: H
authors.lastname: Okajima
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Inomata
authors.forename: Kunio
authors.initials: K
authors.lastname: Doi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods