Integrated electronic detection of biomolecules.
Electronics offers several unique opportunities for the detection and characterization of biomolecules such as oligonucleotides and proteins. Solid-state microfabrication technology, similar to that used to make integrated circuits, can be employed to make integrated electronic sensing systems that are capable of simultaneously detecting multiple molecules. Here, we review some of the capabilities afforded by electronics for rapid and sensitive detection of biomolecules and discuss a recent demonstration of a multi-marker electronic sensing system for detection of uropathogens in clinical samples.
Parviz
Babak A
BA
Department of Electrical Engineering, Campus Box 352500, University of Washington, Seattle, WA 98195, USA. parviz@u.washington.edu
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods / Q000639:trends; D001709:Biotechnology / Q000295:instrumentation / Q000639:trends; D039301:Computers, Molecular / Q000639:trends; D004581:Electronics / Q000295:instrumentation* / Q000639:trends; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods / Q000639:trends; D009696:Nucleic Acids / Q000032:analysis; D011506:Proteins / Q000032:analysis
D009696:Nucleic Acids; D011506:Proteins