title: Acute smoking-induced alterations in Doppler echocardiographic measurements in chronic smokers.
abstract: Acute effects of smoking on left ventricular function have been studied previously. However, effects on right ventricular function have not yet been investigated. In this study, we attempted to investigate, through a combination of conventional and tissue Doppler imaging (TDI), the acute effects of smoking on both left and right ventricular function in chronic smokers. Thirty chronic smokers (with smoking habits of > or =1 pack/day for 74 +/- 1.3 years) underwent a complete transthoracic echocardiographic examination (2-dimensional, pulsed-wave Doppler transmitral and transtricuspid recordings, and TDI recordings of mitral and tricuspid annular velocities) by 3.5-MHz sector transducer. Pulsed-wave Doppler indices of left and right ventricular diastolic function-such as mitral and tricuspid inflows, peak early (E) and late (A) velocities, and E/A ratios-were obtained by conventional Doppler and TDI. Echocardiographic indices of the left and right ventricles--including isovolumetric relaxation time, isovolumetric contraction time, ejection time, and myocardial performance index of right ventricle-were also measured before and 30 minutes after each subject smoked a cigarette. Both mitral and tricuspid inflow measurements changed significantly after smoking a cigarette. Among the TDI measurements, mitral lateral annulus and tricuspid lateral annulus (diastolic, but not systolic) velocities changed after smoking a cigarette. Also, the right ventricular myocardial performance index increased immediately after smoking a cigarette. We found that acute cigarette smoking impaired both left and right ventricular diastolic function in chronic smokers.
authors.affiliation: Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey. drkarakaya@yahoo.com
authors.forename: Osman
authors.initials: O
authors.lastname: Karakaya
authors.forename: Irfan
authors.initials: I
authors.lastname: Barutcu
authors.forename: Ali Metin
authors.initials: AM
authors.lastname: Esen
authors.forename: Dayimi
authors.initials: D
authors.lastname: Kaya
authors.forename: Muhsin
authors.initials: M
authors.lastname: Turkmen
authors.forename: Mehmet
authors.initials: M
authors.lastname: Melek
authors.forename: Ersel
authors.initials: E
authors.lastname: Onrat
authors.forename: Ozlem Batukan
authors.initials: OB
authors.lastname: Esen
authors.forename: Atac
authors.initials: A
authors.lastname: Celik
authors.forename: Celal
authors.initials: C
authors.lastname: Kilit
authors.forename: Mustafa
authors.initials: M
authors.lastname: Saglam
authors.forename: Cevat
authors.initials: C
authors.lastname: Kirma
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology*; D018487:Ventricular Dysfunction, Left / Q000209:etiology*; D018497:Ventricular Dysfunction, Right / Q000209:etiology*