title: Oral manifestations of Cowden's disease. Presentation of a clinical case.
abstract: Cowden's disease, or multiple hamartoma syndrome, is an autosomal dominant genodermatosis, characterized by the presence of multiple cutaneous hamartomas, oral fibromas and benign acral keratosis. It affects multiple organs (breast, thyroids, stomach, colon), with the strong possibility of malignant neoplasia developing in these organs. We present a case of this rare syndrome, highlighting the presentation of some clinical characteristics that, in suspected cases, can help to establish an early diagnosis of this disease, this being of great importance given the high frequency of tumors in people with this clinical picture.
authors.affiliation: C.S. Peñarroya, Córdoba. 957485094@terra.es
authors.forename: Rafael
authors.initials: R
authors.lastname: Segura Saint-Gerons
authors.forename: Alejandro
authors.initials: A
authors.lastname: Ceballos Salobreña
authors.forename: Mariano
authors.initials: M
authors.lastname: Toro Rojas
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Gándara Rey
mesh_terms: D005260:Female; D005881:Gingiva / Q000473:pathology; D006223:Hamartoma Syndrome, Multiple / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*