title: Determination of pilocarpine by HPLC in presence of isopilocarpine a pH-sensitive polymer in ophthalmic dispersions.
abstract: Quantification of pilocarpine in the presence of the epimer isopilocarpine in polymeric dispersions is reported. The method describes a technique using reversed-phase HPLC and UV detection of pilocarpine in the presence of a pH-sensitive polymer. As this method does not require prior sample preparation it will be of special interest for process control and development.
authors.affiliation: School of Pharmacy, University of Geneva, Geneva, Switzerland.
authors.forename: H
authors.initials: H
authors.lastname: Ibrahim
authors.forename: T
authors.initials: T
authors.lastname: Boye
authors.forename: M
authors.initials: M
authors.lastname: Wermeille
authors.forename: R
authors.initials: R
authors.lastname: Gurny
authors.forename: P
authors.initials: P
authors.lastname: Buri