title: [Saponins of polygalacic acid type from Platycodon grandiflorum].
abstract: OBJECTIVE
  To isolate triterpene saponins of polygalacic acid type from the roots of Platycodon grandiflorum (Jacq.) A. DC and to identify their structures.
  
  
  METHODS
  The compounds were separated by means of extraction, chromatography on silica gel, MPLC and HPLC, and their structures were elucidated on the basis of spectral analyses (FAB-MS, IR, 1H NMR, 13C NMR etc.).
  
  
  RESULTS
  Three triterpene saponins were isolated from the roots of Platycodon grandiflorum. They were identified as 3-O-beta-D-laminaribiosyl polygalacic acid (I), 3-O-beta-D-glucopyranosyl polygalacic acid (II), polygalacin D (III), separately.
  
  
  CONCLUSIONS
  Compound I is a new compound, compounds II, III are known triterpene saponins. The compound I and II were isolated from the plant for the first time, which is also the monodesmoside from the plant for the first time.
authors.affiliation: School of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, China.
authors.forename: Wen-wei
authors.initials: WW
authors.lastname: Fu
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Hou
authors.forename: De-qiang
authors.initials: DQ
authors.lastname: Dou
authors.forename: Hui-ming
authors.initials: HM
authors.lastname: Hua
authors.forename: Mao-hua
authors.initials: MH
authors.lastname: Gui
authors.forename: Rui
authors.initials: R
authors.lastname: Fu
authors.forename: Ying-jie
authors.initials: YJ
authors.lastname: Chen
authors.forename: Yue-hu
authors.initials: YH
authors.lastname: Pei
mesh_terms: D008968:Molecular Conformation; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D031238:Platycodon / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C523478:3-O-beta-D-glucopyranosyl polygalacic acid; C523477:3-O-beta-D-laminaribiosyl polygalacic acid; D012503:Saponins