title: [Migration of bisphenol A and benzophenones from paper and paperboard products used in contact with food].
abstract: Migration of bisphenol A (BPA) and benzophenones, i.e., benzophenone (BZ), 4-(dimethylamino)benzophenone (DMAB), Michler's ketone (MK) and 4,4'-bis(diethylamino)benzophenone (DEAB), from 21 paper and paperboard products (15 recycled paperboard boxes and 6 virgin paper products) used in contact with food was examined. Migration levels of compounds from recycled paperboard were compared under various food-simulating conditions. BPA showed the highest migration into 20% ethanol and benzophenones into 95% ethanol. No compounds migrated from virgin paper products, but compounds did migrate into food simulants from recycled paperboard food boxes. BPA migrated into 20% ethanol from all recycled paperboard food boxes between 1.0 and 18.7 ng/mL. Into 95% ethanol, migration of BZ was observed in 8 samples (1.0-18.9 ng/mL), DMAB in 12 samples (1.2-3.7 ng/mL), MK in 13 samples (1.9-9.0 ng/mL), and DEAB in 13 samples (1.0-10.6 ng/mL). The highest migration level was 27.2 ng/mL and most of the migration levels were below 10 ng/mL. These values are sufficiently low compared with the TDI and NOAEL levels. Moreover, the amount of food in daily meals that comes into contact with paperboard products is relatively small. Consequently, it was concluded that there was no safety concern regarding the tested compounds in recycled paperboard food boxes.
authors.affiliation: Osaka City Institute of Public Health and Environmental Sciences: 8-34, Tojo-cho, Tennouji-ku, Osaka 543-0026, Japan.
authors.forename: Asako
authors.initials: A
authors.lastname: Ozaki
authors.forename: Chie
authors.initials: C
authors.lastname: Kawasaki
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Kenichi
authors.initials: K
authors.lastname: Tanamoto
mesh_terms: D001559:Benzhydryl Compounds; D001577:Benzophenones / Q000032:analysis*; D003247:Conservation of Natural Resources; D018857:Food Packaging; D010209:Paper; D010636:Phenols / Q000032:analysis*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D001577:Benzophenones; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds