title: Poly(N-acryloylsarcosine methyl ester) protein-resistant surfaces.
abstract: A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward the adsorption of fibrinogen and lysozyme. Deposition and UV irradiation of the polymer through a masked grid are found to be effective ways for generating negative and positive image protein arrays, respectively, onto a range of different substrate materials.
authors.affiliation: Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, England, U.K.
authors.forename: D O H
authors.initials: DO
authors.lastname: Teare
authors.forename: W C E
authors.initials: WC
authors.lastname: Schofield
authors.forename: R P
authors.initials: RP
authors.lastname: Garrod
authors.forename: J P S
authors.initials: JP
authors.lastname: Badyal
mesh_terms: D000327:Adsorption; D005340:Fibrinogen; D005998:Glycine; D009113:Muramidase; D010455:Peptides; D011091:Polyesters; D011485:Protein Binding; D011506:Proteins; D012521:Sarcosine / Q000031:analogs & derivatives; D013499:Surface Properties
chemical_list: D010455:Peptides; D011091:Polyesters; D011506:Proteins; C015475:polysarcosine; C038264:sarcosine methyl ester; D005340:Fibrinogen; D009113:Muramidase; D005998:Glycine; D012521:Sarcosine