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Polymorphism in the evolution of quality control of drugs is discussed and the possible relationship between polymorphism and bioavailability of drugs demonstrated. The advantages and limitations of the techniques used for the characterization of polymorphs are described.
Bouche
R
R
Laboratoire d'Analyse des Médicaments, Université Catholique de Louvain, avenue E. Mounier 73, 1200 Bruxelles, Belgique.