title: Human pharmacokinetics of analgesics and methods for their determination in biological fluids.
abstract: The main pharmacokinetic data of analgesics--biological half-lives, apparent volumes of distribution, total body clearances--obtained in humans, and their clinical relevance are summarized. Special emphasis has been given to the analytical methods used for the quantitative determination of these drugs in biological fluids.
authors.affiliation: Department of Pharmacokinetics and Drug Metabolism, Chemical Works of Gedeon Richter Ltd, P.O. Box 27, H-1475 Budapest 10, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Miskolczi
authors.forename: L
authors.initials: L
authors.lastname: Vereczkey