title: Bimaxillary osteotomy in a female patient with hemophilia A.
abstract: We report here a case of a 22-year-old female patient with hemophilia A who had a bimaxillary osteotomy operation. Adequate replacement of Factor VIII and DDAVP(1 deamino-8-D-arginine vasopressin) led to the achievement of hemostasis during and after the surgery. Le Fort I maxillary osteotomy and mandibular sagittal split osteotomies were done to correct the facial profile of this hemophiliac patient with a class III malocclusion and posterior open-bite deformity. Careful preoperative evaluation and close cooperation with the hematologist are required if surgery is to be successful. The operation was uneventful and no postoperative complication was observed.
authors.affiliation: Plastic, Reconstructive and Aesthetic Surgery Department, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey. zg@e-kolay.net
authors.forename: Mehmet Zeki
authors.initials: MZ
authors.lastname: Güzel
authors.forename: Hakan
authors.initials: H
authors.lastname: Arslan
authors.forename: Ali
authors.initials: A
authors.lastname: Kiliç
mesh_terms: D000328:Adult; D003029:Coagulants / Q000627:therapeutic use; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D005169:Factor VIII / Q000627:therapeutic use; D005260:Female; D006467:Hemophilia A / Q000503:physiopathology* / Q000517:prevention & control; D006488:Hemostasis, Surgical; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008313:Malocclusion, Angle Class III / Q000601:surgery; D008334:Mandible / Q000601:surgery*; D008437:Maxilla / Q000601:surgery*; D024343:Open Bite / Q000601:surgery; D010027:Osteotomy / Q000379:methods*; D019340:Osteotomy, Le Fort; D010347:Patient Care Planning
chemical_list: D003029:Coagulants; D006490:Hemostatics; D005169:Factor VIII; D003894:Deamino Arginine Vasopressin