title: A new spiro-sesquiterpene from the sponge Dysidea fragilis.
abstract: A new spiro-sesquiterpene, spirofragilin (1), along with a known related sesquiterpene, dehydroherbadysidolide (2), have been isolated from the marine sponge Dysidea fragilis collected in the South China Sea. The structure of 1 was elucidated on the basis of detailed spectroscopic analysis.
authors.affiliation: State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Zhangjiang Hi-Tech Park, Shanghai, China.
authors.forename: Z-G
authors.initials: ZG
authors.lastname: Yu
authors.forename: K-S
authors.initials: KS
authors.lastname: Bi
authors.forename: Y-W
authors.initials: YW
authors.lastname: Guo
authors.forename: E
authors.initials: E
authors.lastname: Mollo
authors.forename: G
authors.initials: G
authors.lastname: Cimino
mesh_terms: D000818:Animals; D047088:Dysidea; D009682:Magnetic Resonance Spectroscopy; D008517:Phytotherapy; D012717:Sesquiterpenes / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry
chemical_list: D012717:Sesquiterpenes; D013141:Spiro Compounds