[General reproductive toxicity assessment in mice exposed to low-level ozone].
OBJECTIVE
To explore the general reproductive toxicity in mice exposed to low-level ozone.


METHODS
Low-level (0.09 approximately 0.18 mg/m3) ozone was created by 15 W ultraviolet light. The mice in 3 experimental groups and a control group were fed in low-level ozone environment or normal environment, respectively, and then the mating experiment was conducted. The pregnancy rate and the weight variations of the female mice were observed. The weight of the live fetuses was observed, and the appearance, bone and internal organs were checked for malformation.


RESULTS
There were no significant differences in any indexes between the experimental groups and the control group.


CONCLUSIONS
Low-level ozone created by 15 W ultraviolet light may not have reproductive toxicity in mice.
Zhou
Zhi-jun
ZJ
Department of Laboratory Animal, Central South University, Changsha, China.
Zhou
Zheng-shi
ZS
Tang
Bai-zheng
BZ
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D005298:Fertility / Q000187:drug effects*; D019570:Inhalation Exposure / Q000009:adverse effects*; D008297:Male; D051379:Mice; D019055:No-Observed-Adverse-Effect Level; D010126:Ozone / Q000633:toxicity*; D011897:Random Allocation; D012098:Reproduction / Q000187:drug effects*; D014466:Ultraviolet Rays
D010126:Ozone