Prognostic factor analysis and proposed prognostic model for conventional treatment of high-grade primary gastric lymphoma.
OBJECTIVE
We conducted a clinical risk factors analysis to define a prognostic model for high-grade primary gastric lymphoma (HG-PGL).


RESULTS
The median event-free survival and overall survival of 214 HG-PGL patients were 54 and 104.5 months, respectively, after a median follow-up duration of 60 months. According to the prognostic factor analysis, survival, advanced age, male gender, higher LDH levels and the presence of ascites were identified as independent prognostic factors for HG-PGL. We identified four groups at different risk: group 1, no adverse effect; group 2, one factor; group 3, two factors; group 4, three or four factors. The new prognostic model showed excellent prognostic capacity to differentiate subgroups according to their risk stratification.


CONCLUSIONS
The proposed new prognostic model for HG-PGL demonstrated a balanced distribution of patients into four groups with good prognostic capacity.
Park
Yeon H
YH
Department of Hematology-Oncology, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea.
Kim
Won S
WS
Bang
Soo M
SM
Lee
Soon I
SI
Uhm
Ji E
JE
Kang
Hye J
HJ
Na
Im I
II
Yang
Sung H
SH
Lee
Seung-Sook
SS
Kim
Kihyun
K
Jung
Chul W
CW
Park
Keunchil
K
Ko
Young H
YH
Ryoo
Baek-Yeol
BY
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011379:Prognosis; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*