Morphometric evaluations of the human nervous system.
It is very important to evaluate and accurately understand the various conditions of the human nervous system. In this review article, we introduce several morphometric reports that are proven to be accurate from the view point of various errors (range of tissue shrinkage ratios, microscopic multiple counting, artifacts of microscopic structures, etc.). We review the following aspects of the selected reports: methodology, developmental research, neuronal differences, gender differences, aging process and miscellaneous (nerve fibers, unmyelinated fibers, in relation to neuropathology, clinical image-analysis and immunohistochemistry).
Goto
Noboru
N
Department of Anatomy, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan. goto@med.showa-u.ac.jp
Goto
Jun
J
D000375:Aging / Q000473:pathology; D003952:Diagnostic Imaging; D005260:Female; D016591:Histocytological Preparation Techniques; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008853:Microscopy; D009420:Nervous System / Q000033:anatomy & histology* / Q000473:pathology / Q000648:ultrastructure; D009474:Neurons; D012727:Sex Characteristics