Potential role of Veillonella spp. as a reservoir of transferable tetracycline resistance in the oral cavity.
Twelve out of 96 Veillonella spp. isolated from oral samples harbored tetracycline resistance genes. The most common resistance gene was tet(M). A tet(M)-positive Veillonella dispar strain was shown to transfer a Tn916-like element to four Streptococcus spp. by conjugation at a frequency of 5.2 x 10(-6) to 4.5 x 10(-5) per recipient.
Ready
D
D
Microbiology, Eastman Dental Hospital, UCLH NHS Foundation Trust, London WC1X 8LD, UK. d.ready@eastman.ucl.ac.uk
Pratten
J
J
Roberts
A P
AP
Bedi
R
R
Mullany
P
P
Wilson
M
M
D001426:Bacterial Proteins / Q000235:genetics; D003227:Conjugation, Genetic; D004251:DNA Transposable Elements / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics; D022761:Gene Transfer, Horizontal; D005798:Genes, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology*; D013291:Streptococcus / Q000235:genetics; D013753:Tetracycline Resistance / Q000235:genetics*; D014678:Veillonella / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification
D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D004269:DNA, Bacterial