Selective TRAIL-induced apoptosis in dysplastic neoplasia of the colon may lead to new neoadjuvant or adjuvant therapies.
Finnberg
Niklas
N
Laboratory of Molecular Oncology and Cell Cycle Regulation, Department of Medicine, the Abramson Comprehensive Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
El-Deiry
Wafik S
WS
D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000517:prevention & control*; D006801:Humans; D008954:Models, Biological; D020360:Neoadjuvant Therapy / Q000379:methods*; D009369:Neoplasms / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000502:physiology*
D000970:Antineoplastic Agents; D011994:Recombinant Proteins; D053221:TNF-Related Apoptosis-Inducing Ligand