title: Non-preventable mumps outbreaks in schoolchildren in Catalonia.
abstract: Various doses of the combined MMR vaccine containing the Rubini mumps strain were distributed in Catalonia in 1994 and 1995. We studied outbreaks of mumps reported from 1997 to 2002 to determine the possible involvement of this vaccine in the appearance of non-preventable mumps outbreaks. A total of 17 mumps outbreaks were declared in the period 1997-2000, 14 of which were in schoolchildren. In 11, it was determined that children were correctly vaccinated. Of these, 10 were non-preventable outbreaks. 66% of cases investigated had ages which coincided with vaccination in the period 1994-1996, during which the MMR vaccine containing the Rubini mumps strain was administered. In Catalonia, during the period 1997-2000, at least two-thirds of mumps cases in schoolchildren could be explained by vaccination with the combined MMR vaccine containing the Rubini strain, which has also been associated with mumps outbreaks amongst vaccinated people in other countries.
authors.affiliation: Department of Health, Generalitat of Catalonia Barcelona, Spain.
authors.forename: Neus
authors.initials: N
authors.lastname: Cardeñosa
authors.forename: Angela
authors.initials: A
authors.lastname: Domínguez
authors.forename: Neus
authors.initials: N
authors.lastname: Camps
authors.forename: Ana
authors.initials: A
authors.lastname: Martínez
authors.forename: Nuria
authors.initials: N
authors.lastname: Torner
authors.forename: Encarna
authors.initials: E
authors.lastname: Navas
authors.forename: Lluís
authors.initials: L
authors.lastname: Salleras
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage*; D009107:Mumps / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology; D012574:Schools; D013030:Spain / Q000453:epidemiology
chemical_list: D022542:Measles-Mumps-Rubella Vaccine