Manifestations of SIV-induced ocular pathology in macaque monkeys.
Simian immunodeficiency virus has been shown to cause acquired immunodeficiency syndrome in macaque monkeys. Data gathered from clinical examination and fundus photography have shown that the lentivirus is capable of the induction of choroidal lesions and retinal hemorrhages in the macaque. These findings demonstrate the potential value of the macaque monkey eye as a model of the retinal pathology routinely seen in human AIDS patients.
Johnson
J K
JK
Department of Anatomy & Cell Biology, KU Medical Center, Kansas City, KS 66160-7400, USA.
Warren
K A
KA
Berman
N E J
NE
Narayan
O
O
Stephens
E B
EB
Joag
S V
SV
Raghavan
R
R
Marcario
J K
JK
Cheney
P D
PD
D000818:Animals; D005128:Eye Diseases / Q000473:pathology / Q000821:virology*; D005654:Fundus Oculi; D008253:Macaca mulatta; D012160:Retina / Q000473:pathology / Q000821:virology; D016097:Simian Acquired Immunodeficiency Syndrome / Q000473:pathology*; D015302:Simian Immunodeficiency Virus