[Portal and superior mesenteric venous thrombosis treated with urokinase infusion via superior mesenteric artery].
Portal and mesenteric venous thrombosis is an uncommon disease, but clinically important, because it accounts for 5% to 15% of acute mesenteric ischemia. The diagnosis is often delayed because the conditions are nonspecific abdominal symptoms. In addition, when this occurs in young individual without any known predisposing factor, the diagnosis may become even more difficult. The treatment of mesenteric venous thrombosis involves anticoagulation therapy alone or in combination with surgery. The addition of thrombolytic therapy to the treatment of portal and mesenteric venous thrombosis may enhance the clearance of thrombus and hasten the clinical improvements. We present a case of mesenteric venous thrombosis treated with catheter-directed infusion of urokinase via the superior mesenteric artery and systemic anticoagulation.
Lee
Hyeug
H
Division of Gastroenterology, Department of Internal Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
Kim
Tae Ho
TH
Oh
Hyun Jong
HJ
Kim
Jin Il
JI
Park
Soo-Heon
SH
Han
Joon-Yeol
JY
Kim
Jae Kwang
JK
Choi
Kyu Young
KY
Chung
In Sik
IS
Lee
Sang Hoon
SH
Hahn
Seong Tai
ST
D000328:Adult; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D017538:Mesenteric Artery, Superior; D008641:Mesenteric Vascular Occlusion / Q000188:drug therapy*; D008642:Mesenteric Veins; D011169:Portal Vein; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*; D020246:Venous Thrombosis / Q000188:drug therapy*
D014568:Urokinase-Type Plasminogen Activator