title: Early supraglottic cancer: how extensive must surgical resection be, if used alone?
abstract: OBJECTIVE
  Two centre based evaluations of oncologic results of endoscopic resection of supraglottic cancer without post-operative irradiation.
  
  
  METHODS
  Twenty-six patients with clinical T1 (n=5) or T2 (n=21) primary squamous cell carcinomas of the supraglottic larynx and with N0 (n=24) or N1 (n=2) neck disease were treated by endoscopic supraglottic laryngectomy coupled with neck dissection(s). Endoscopic resection was standardized whereas neck dissections (NDs) varied from classical modified radical ND to selective ND of levels I to IV.
  
  
  RESULTS
  Pathologically, three T2 patients were upstaged to T3, four N0 patients to N1 and one N2 patient down-staged to N1. Within an average of 42 months, there were no local failures and only one regional failure.
  
  
  CONCLUSIONS
  Endoscopic resection of T1 and T2 supraglottic cancer without post-operative irradiation achieved good oncological results. No patients with lateralized primary cancers were found to have contralateral cancer on pathological evaluation from bilateral dissections.
authors.affiliation: Department of Otolaryngology, Head & Neck Surgery, Philipps University of Marburg, Marburg, Germany.
authors.forename: A A
authors.initials: AA
authors.lastname: Dünne
authors.forename: R K
authors.initials: RK
authors.lastname: Davis
authors.forename: C V
authors.initials: CV
authors.lastname: Dalchow
authors.forename: A M
authors.initials: AM
authors.lastname: Sesterhenn
authors.forename: J A
authors.initials: JA
authors.lastname: Werner
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D004825:Epiglottis / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D007828:Laryngoscopy; D008297:Male; D037981:Neck Dissection / Q000379:methods*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014481:United States; D014827:Vocal Cords / Q000473:pathology