title: Anomalous reflection of gold applicable for a practical protein-detecting chip platform.
abstract: A simple, convenient and label-free fiber optic detection system based on the characteristic property, 'anomalous reflection (AR)' of gold was developed and preliminary experiments showed that the AR signals were sensitive enough to monitor protein-peptide interactions on solid surfaces.
authors.affiliation: The COE21 Program and Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: Sinya
authors.initials: S
authors.lastname: Watanabe
authors.forename: Kenji
authors.initials: K
authors.lastname: Usui
authors.forename: Kin-ya
authors.initials: KY
authors.lastname: Tomizaki
authors.forename: Kotaro
authors.initials: K
authors.lastname: Kajikawa
authors.forename: Hisakazu
authors.initials: H
authors.lastname: Mihara
mesh_terms: D000595:Amino Acid Sequence; D015374:Biosensing Techniques; D017979:Gold Colloid / Q000737:chemistry*; D046208:Microchip Analytical Procedures; D008969:Molecular Sequence Data; D040081:Protein Array Analysis; D025941:Protein Interaction Mapping; D011506:Proteins / Q000737:chemistry; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D017979:Gold Colloid; D011506:Proteins