title: T-cell/histiocyte-rich large B-cell lymphoma associated with a near-tetraploid karyotype and complex genetic abnormalities.
abstract: Cytogenetic data for T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) are scarcely available. We report here a case of THRLBCL with a near-tetraploid karyotype and complex chromosomal aberrations, without rearrangement of BCL2 or BCL6, and characterized pathologically by a variegated morphologic appearance with areas resembling nodular lymphocyte-predominant Hodgkin's lymphoma (NLPHL).
authors.affiliation: Department of Pathology, CHU Sart-Tilman, Liege, Belgium. L.deLeval@ulg.ac.be
authors.forename: Laurence
authors.initials: L
authors.lastname: de Leval
authors.forename: Nancy Lee
authors.initials: NL
authors.lastname: Harris
authors.forename: Serge
authors.initials: S
authors.lastname: Lampertz
authors.forename: Christian
authors.initials: C
authors.lastname: Herens
mesh_terms: D002869:Chromosome Aberrations; D006644:Histiocytes / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D007621:Karyotyping; D016393:Lymphoma, B-Cell / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D013601:T-Lymphocytes / Q000473:pathology*