Cancelling planned actions following mild traumatic brain injury.
Mild traumatic brain injury (mTBI) leads to a variety of attentional, cognitive, and sensorimotor deficits. An important aspect of behavior that intersects each of these functions is the ability to cancel a planned action. Thus, the purpose of this study was to determine the effects of mTBI on the ability to perform a countermanding saccade task. In this task, participants were asked to generate a saccade to a target appearing in peripheral vision, but to inhibit saccade execution if an auditory stop signal was presented. The delay between the appearance of the peripheral target and the presentation of the auditory stop signal was varied between 0 and 125ms. We found that the change in the probability of cancelling the saccade as a function of this delay was no different between participants with mTBI tested within 2 days of their injury and matched controls. However, saccadic reaction times and the stop signal reaction time were unexpectedly faster in the participants with mTBI and, furthermore, they inaccurately inhibited saccades during 15% of the trials with no stop signal. Taken together, this data suggests that the ability to cancel planned actions is subtly yet adversely affected by mTBI.
DeHaan
Alex
A
Department of Human Physiology and Institute of Neuroscience, University of Oregon, 122C Esslinger Hall, Eugene, OR 97403-1240, USA.
Halterman
Charlene
C
Langan
Jeanne
J
Drew
Anthony S
AS
Osternig
Louis R
LR
Chou
Li-Shan
LS
van Donkelaar
Paul
P
D000328:Adult; D001930:Brain Injuries / Q000523:psychology*; D003463:Cues; D003657:Decision Making / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology*