Statin use before by-pass surgery decreases the incidence and shortens the duration of postoperative atrial fibrillation.
BACKGROUND
The aim of the present observational study is to search the incidence of postoperative atrial fibrillation (AF) in patients with or without preoperative statin treatment.


RESULTS
The population consisted of 362 consecutive patients (267 on and 95 not on statin). Diabetes mellitus was more frequent in statin group (p = 0.03). Other demographic and procedural variables were similar in the both groups (All p > 0.05). Postoperative AF was less frequent and its duration was shorter in statin group compared to non-statin group (p = 0.03 and 0.0001, respectively). The Kaplan-Meier analysis showed the protective effect of statins against the risk of developing AF (p = 0.01).


CONCLUSIONS
Statin treatment before the by-pass surgery decreases the incidence and shortens the duration of postoperative AF.
Ozaydin
Mehmet
M
Departments of Cardiology and Cardiovascular Surgery, Suleyman Demirel University Medical School, Isparta, Turkey. mehmetozaydin@hotmail.com
Dogan
Abdullah
A
Varol
Ercan
E
Kapan
Sahin
S
Tuzun
Nurullah
N
Peker
Oktay
O
Aslan
Suleyman M
SM
Altinbas
Ahmet
A
Ocal
Ahmet
A
Ibrisim
Erdogan
E
D000368:Aged; D001281:Atrial Fibrillation / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015994:Incidence; D007249:Inflammation; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012306:Risk
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors