[Insulin therapy in patients with severe hypertriglyceridemia].
A series of seven patients with severe hypertriglyceridemia (triglyceride levels > 1000 mg/dL) is presented. Four of the patients were diabetics, two of them were in treatment with anti-retroviral drugs, and three of them presented acute pancreatitis. In all patients intravenous infusion of insulin was initiated at a rate of 0.05-2 U/kg/day. Two and a half days after this treatment, the serum triglyceride level remained lower than 400 mg/dL. There were no complications during the treatment. The long treatment included basal insulin, fibrates and avoidance of pharmacotherapy. Insulin therapy for diabetic and non-diabetic patients with severe hypertriglyceridemia is an effective and safe treatment.
Tamez-Pérez
Héctor Eloy
HE
Departamento de Endocrinología, Divisíon de Medicina Interna, Hospital de Especialidades 25, Instituto Mexicano del Seguor Social, Monterray, Nuevo Léon. hectoreloytamez@aol.com
Sáenz-Gallegos
Ramón
R
Hernández-Rodríguez
Karina
K
Forsbach-Sánchez
Gerardo
G
Gómez-de Ossio
María Dolores
MD
Fernández-Garza
Nancy
N
Zapata-de la Garza
Eduardo
E
Tamez-Peña
Alejandra Lorena
AL
D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000188:drug therapy*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
D007328:Insulin