title: [Early diagnosis of Lyme borreliosis].
abstract: The local inflammatory reaction following a tick bite varies considerably, so that in particular the frequently atypical variations result in a wrong diagnosis and thus to inappropriate treatment. If a tick bite is followed within three weeks by flue-like or neurological symptoms, or joint swelling in the vicinity of the bite, a serological investigation work-up should be carried out. In the early stage, however, Borrelia-specific antibodies can be detected in only 30-80% of the patients. However, during the further course of the illness, the specific IgM and IgG antibody titers almost always increase.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie der TU München. h.hofmann@lrz.tum.de
authors.forename: H
authors.initials: H
authors.lastname: Hofmann
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D025065:Borrelia burgdorferi / Q000276:immunology; D018849:Controlled Clinical Trials as Topic; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000008:administration & dosage / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay; D015787:Erythema Chronicum Migrans / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D008193:Lyme Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000517:prevention & control; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D004318:Doxycycline