Resistance training improves muscle function and body composition in patients with hyperthyroidism.
OBJECTIVE
To evaluate the effect of resistance training on skeletal muscle performance and body composition in patients with medically treated hyperthyroidism.


METHODS
Nonrandomized controlled trial.


METHODS
Large public tertiary hospital.


METHODS
Sixteen sedentary patients with recent clinical diagnosis and laboratory confirmation of hyperthyroidism (7 men, 9 women; age, 38+/-11 y; weight, 58.4+/-2.6 kg; height, 1.6+/-0.3m) were assigned to the control group (medical therapy; n=9) or training group (medical therapy associated with resistance training; n=7). An age- and sex-matched healthy group served as controls (3 men, 5 women; age, 40+/-3 y; weight, 68.4+/-4.3 kg; height, 1.6+/-0.3m).


METHODS
Resistance training twice a week for 16 weeks.


METHODS
Peak muscular strength (by dynamometry and 1 repetition maximum method) and endurance (30% of peak force) for 7 movements and anthropometric measurements.


RESULTS
The hyperthyroid patients as a group had lower baseline overall strength values when compared with healthy subjects (200.3+/-16.0 kg vs 274.9+/-21.8 kg, respectively; P=.006). Overall absolute increases in strength (49 kg vs 91 kg, P<.05) and endurance (78.5x10(2)kg/s vs 176.9x10(2)kg/s, P<.05) were higher in the training group compared with the control group. Body weight increased in both groups, but the sum of muscular circumference increased only in the training group (training group, 92.6+/-3.3 cm vs 97.1+/-3.8 cm; control group, 94.6+/-2.2 cm vs 94.4+/-2.1cm; P<.05), with no change in the sum of skinfolds.


CONCLUSIONS
Resistance training accelerates the recovery of skeletal muscle function and promotes weight gain based on muscle mass improvement in patients with medically treated hyperthyroidism.
Bousquet-Santos
Kelb
K
Department of Physiology and Pharmacology, Universidade Federal Fluminense, Niteroi, RJ, Brazil.
Vaisman
Mario
M
Barreto
Ney D
ND
Cruz-Filho
Rubens A
RA
Salvador
Bruno A
BA
Frontera
Walter R
WR
Nobrega
Antonio C
AC
D000328:Adult; D001823:Body Composition; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000503:physiopathology / Q000534:rehabilitation*; D016014:Linear Models; D008297:Male; D018482:Muscle, Skeletal / Q000502:physiology; D010806:Physical Education and Training; D010807:Physical Endurance; D018709:Statistics, Nonparametric