title: Synthesis and reactivity of imide-derived bisvinyl phosphates. Reactivity of 2,6-disubstituted 1,4-dihydropyridines.
abstract: Symmetrical and unsymmetrical 2,6-disubstituted dihydropyridines were prepared in high yields under mild conditions using the Suzuki and Stille Pd-catalyzed coupling reactions of imide-derived bisvinyl phosphates with a range of aryl, heteroaryl, and alkenyl moieties. The alkylation reaction at C-4 easily afforded original tri- and tetrasubstituted dihydropyridines. Hydrolysis of the latter under acidic condition provided efficiently either open-chain 1,5-diketones or di- or trisubstituted pyridines.
authors.affiliation: ICOA, UMR 6005, Université d'Orléans, BP 6759, 45067 Orléans Cedex 2, France.
authors.forename: Deborah
authors.initials: D
authors.lastname: Mousset
authors.forename: Isabelle
authors.initials: I
authors.lastname: Gillaizeau
authors.forename: Andréa
authors.initials: A
authors.lastname: Sabatié
authors.forename: Pascal
authors.initials: P
authors.lastname: Bouyssou
authors.forename: Gérard
authors.initials: G
authors.lastname: Coudert