title: Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes: data from the Italian Tamoxifen Trial.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Bonanni
authors.forename: Debora
authors.initials: D
authors.lastname: Macis
authors.forename: Patrick
authors.initials: P
authors.lastname: Maisonneuve
authors.forename: Harriet A
authors.initials: HA
authors.lastname: Johansson
authors.forename: Giacomo
authors.initials: G
authors.lastname: Gucciardo
authors.forename: Pasquale
authors.initials: P
authors.lastname: Oliviero
authors.forename: Roberto
authors.initials: R
authors.lastname: Travaglini
authors.forename: Maria G
authors.initials: MG
authors.lastname: Muraca
authors.forename: Nicole
authors.initials: N
authors.lastname: Rotmensz
authors.forename: Umberto
authors.initials: U
authors.lastname: Veronesi
authors.forename: Andrea U
authors.initials: AU
authors.lastname: Decensi
mesh_terms: D000328:Adult; D000368:Aged; D016588:Anticarcinogenic Agents / Q000378:metabolism*; D018931:Antineoplastic Agents, Hormonal / Q000378:metabolism*; D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D020847:Estrogen Receptor Modulators / Q000378:metabolism*; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D019584:Hot Flashes / Q000517:prevention & control*; D006801:Humans; D007558:Italy; D008875:Middle Aged; D011110:Polymorphism, Genetic; D016032:Randomized Controlled Trials as Topic; D013629:Tamoxifen / Q000378:metabolism*
chemical_list: D016588:Anticarcinogenic Agents; D018931:Antineoplastic Agents, Hormonal; D020847:Estrogen Receptor Modulators; D013629:Tamoxifen; D019389:Cytochrome P-450 CYP2D6