Polycomb, pairing and PIWI--RNA silencing and nuclear interactions.
In Drosophila, the RNA interference (RNAi) genes participate in Polycomb (Pc)-mediated transgene silencing. Recently, the involvement of the RNAi genes in Pc silencing, pairing-sensitive silencing and long-range contacts among Pc-associated sequences has been explored. These Pc-associated sequences are involved with the control of the proper expression of developmental HOX genes.
Kavi
Harsh H
HH
Division of Biological Sciences, Tucker Hall, University of Missouri, Columbia, MO 65211, USA.
Fernandez
Harvey R
HR
Xie
Weiwu
W
Birchler
James A
JA
D000818:Animals; D060565:Argonaute Proteins; D002467:Cell Nucleus / Q000378:metabolism; D023902:Chromosome Pairing; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000235:genetics* / Q000378:metabolism; D008957:Models, Genetic; D063150:Polycomb Repressive Complex 1; D011506:Proteins / Q000378:metabolism*; D034622:RNA Interference; D034743:RNA-Induced Silencing Complex
D060565:Argonaute Proteins; D029721:Drosophila Proteins; C066770:Pc protein, Drosophila; D011506:Proteins; D034743:RNA-Induced Silencing Complex; C116498:piwi protein, Drosophila; D063150:Polycomb Repressive Complex 1