title: Correlation of cholesteatomas perimatrix thickness with patient's age.
abstract: Cholesteatoma may occur either in children as in adults; in children, however, they have a more aggressive and extensive growth.
  
  
  OBJECTIVE
  To compare the thickness of the perimatrix, in microm, between adults (>18 years old) and children cholesteatomas.
  
  
  METHODS
  transversal cohort.
  
  
  METHODS
  74 cholesteatomas (35 of children) obtained from othologic surgeries were included, fixed in formol 10%. It was made laminas with HE and Picrossisius, with were studied at the optic microscope. We obtained digital images of the laminas at the Image Pro-Plus and we used Spearman's coefficient for data analysis. Differences were considered statistically significant if P.
authors.affiliation: Program of Post-Graduation in Medical Sciences: Pediatrics-UFRGS, and Hospital de Clínicas de Porto Alegre-Federal University of Rio Grande do Sul.
authors.forename: Cristina
authors.initials: C
authors.lastname: Dornelles
authors.forename: Sady Selaimen
authors.initials: SS
authors.lastname: da Costa
authors.forename: Luíse
authors.initials: L
authors.lastname: Meurer
authors.forename: Cláudia
authors.initials: C
authors.lastname: Schweiger
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000150:complications / Q000473:pathology*; D002908:Chronic Disease; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005109:Extracellular Matrix / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010033:Otitis Media / Q000209:etiology / Q000473:pathology*