title: Prognostic markers under watchful waiting and radical prostatectomy.
abstract: A suitable setting to analyze factors that determine prognosis or treatment response in prostate cancer is an unbiased comparison of radical prostatectomy and watchful waiting as in the Scandinavian Prostate Cancer Group Trial number 4. In our previous presentation of 10-year results, we studied Gleason score, serum prostate-specific antigen (PSA) at diagnosis, and age at diagnosis as modifiers of the effect of radical prostatectomy on survival. Because overall prognostic information obtained by these parameters or by tumor stage was not provided in our publication, we now present these data in the two study arms separately.
authors.affiliation: Regional Oncologic Center, University Hospital, Uppsala, Sweden. lars.holmberg@akademiska.se
authors.forename: Lars
authors.initials: L
authors.lastname: Holmberg
authors.forename: Anna
authors.initials: A
authors.lastname: Bill-Axelson
authors.forename: Hans
authors.initials: H
authors.lastname: Garmo
authors.forename: Juni
authors.initials: J
authors.lastname: Palmgren
authors.forename: Bo Johan
authors.initials: BJ
authors.lastname: Norlén
authors.forename: Hans Olov
authors.initials: HO
authors.lastname: Adami
authors.forename: Jan Erik
authors.initials: JE
authors.lastname: Johansson
mesh_terms: D015415:Biomarkers; D006801:Humans; D008297:Male; D011379:Prognosis; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery*; D016019:Survival Analysis
chemical_list: D015415:Biomarkers