title: Occupational manganese neurotoxicity provoked by hepatitis C.
abstract: Manganese neurotoxicity developed in a highly exposed worker after asymptomatic, moderate hepatic dysfunction from hepatitis C infection. Antiviral therapy was accompanied by resolution of increased blood manganese levels and neurologic improvement. Even asymptomatic hepatic dysfunction may impair manganese clearance and place highly exposed persons at risk for toxicity.
authors.affiliation: Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA. schaumbu@aecom.yu.edu
authors.forename: Herbert H
authors.initials: HH
authors.lastname: Schaumburg
authors.forename: Steven
authors.initials: S
authors.lastname: Herskovitz
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Cassano
mesh_terms: D000328:Adult; D005260:Female; D006526:Hepatitis C / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D020149:Manganese Poisoning / Q000175:diagnosis* / Q000209:etiology*; D008669:Metallurgy; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects*