CT and MRI of hepatic abscess in patients with chronic granulomatous disease.
OBJECTIVE
We describe the spectrum of radiologic appearances of hepatic abscesses in patients with chronic granulomatous disease (CGD), a hereditary immunodeficiency presenting in childhood that occurs at a rate of 1 in 200,000-250,000 live births and predisposes patients to infection with catalase-positive organisms.


CONCLUSIONS
Hepatic abscesses in patients with CGD show an atypical radiologic appearance compared with sporadic hepatic abscesses, and they are characterized by homogeneous enhancement and multiseptal enhancement. In the appropriate clinical setting, the appearance of an enhancing mass should suggest the possibility of a CGD-related hepatic abscess.
Garcia-Eulate
Reyes
R
Molecular Imaging Program, National Cancer Institute, Bldg. 10, Rm. B3B69, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Hussain
Nadeem
N
Heller
Theo
T
Kleiner
David
D
Malech
Harry
H
Holland
Steven
S
Choyke
Peter L
PL
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D008100:Liver Abscess / Q000150:complications* / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed