Expression of integrins in the endometrium of women with recurrent miscarriage.
Immunostaining intensity for alpha(1), alpha(4), alpha(v)beta(3), and beta(3) was assessed by H score in timed peri-implantation endometrium from 21 women with unexplained recurrent miscarriage and 16 healthy fertile women. No significant difference in H scores in gland epithelium, luminal epithelium, stroma, or blood vessels was observed between the two groups, suggesting that alpha(1), alpha(4), alpha(v)beta(3) and beta(3) integrins are expressed normally in the endometrium of women with unexplained recurrent miscarriage.
Tuckerman
Elizabeth M
EM
Biomedical Research Unit, Sheffield, United Kingdom. elizabeth.tuckerman@sth.nhs.uk
Laird
Susan M
SM
Prakash
Alka
A
Li
Tin Chiu
TC
D000026:Abortion, Habitual / Q000378:metabolism*; D000328:Adult; D004717:Endometrium / Q000378:metabolism*; D005260:Female; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D011247:Pregnancy; D016037:Single-Blind Method; D014018:Tissue Distribution
D016023:Integrins