title: Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea.
abstract: Five new monoterpene glycosides, rhodiolosides A-E (1-5), were isolated from the roots of Rhodiola rosea (Crassulaceae). Their structures were elucidated as (2E,6E,4R)-4,8-dihydroxy-3,7-dimethyl-2,6-octadienyl beta-D-glucopyranoside (1), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl alpha-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside (2), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranoside (3), (2E,4R)-4,7-dihydroxy-3,7-dimethyl-2-octenyl beta-D-glucopyranoside (4), and (2E)-7-hydroxy-3,7-dimethyl-2-octenyl alpha-L-arabinopyranosyl(1-->6)-beta-D-glucopyranoside (5), on the basis of various spectroscopic analyses and chemical degradation.
authors.affiliation: College of Pharmacy, Xinjiang Medical University, 8 Xinyi Road, Urumki 830054, P.R. China.
authors.forename: Guizhi
authors.initials: G
authors.lastname: Ma
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Deqiang
authors.initials: D
authors.lastname: Dou
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Chang
authors.forename: Hong
authors.initials: H
authors.lastname: Bai
authors.forename: Tadaaki
authors.initials: T
authors.lastname: Satou
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Dianjia
authors.initials: D
authors.lastname: Sun
authors.forename: Tingguo
authors.initials: T
authors.lastname: Kang
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Nikaido
authors.forename: Kazuo
authors.initials: K
authors.lastname: Koike
mesh_terms: D002240:Carbohydrate Sequence; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005960:Glucosides / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D029771:Rhodiola / Q000737:chemistry*
chemical_list: D005960:Glucosides; D006027:Glycosides; D039821:Monoterpenes; D010636:Phenols; C009172:rhodioloside