Comparison of the adhesion scoring systems used in animal models and assessment of interobserver reproducibility.
Two commonly used adhesion scoring systems were compared and the interobserver variability was assessed in 30 Wistar albino rats. Thirty-five milligrams per kilogram leflunomide was administered orally and intraperitoneally. Two weeks later, adhesion formation was assessed using the two scoring systems. The results showed that the two currently used adhesion scoring systems are subjective and the final results change depending on the observer and the type of the scoring system that has been used.
Demirturk
Fazli
F
Department of Gynecology and Obstetrics, Gaziosmanpasa University Faculty of Medicine, Tokat, Turkey. fazlimd@yahoo.com
Aytan
Hakan
H
Caliskan
Ahmet C
AC
D000005:Abdomen; D000291:Adnexal Diseases / Q000473:pathology*; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D015588:Observer Variation; D011183:Postoperative Complications / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D012720:Severity of Illness Index; D000267:Tissue Adhesions / Q000473:pathology*