title: Transitional cell carcinoma of bladder with lamina propria invasion in a 10-year-old boy.
abstract: Transitional cell carcinoma of the bladder is a rare entity in childhood. We report on a 10-year-old boy with transitional cell carcinoma of the bladder who presented with gross hematuria. Ultrasonography revealed a papillary lesion in the bladder. Cystoscopic evaluation showed a papillary lesion with a thick stalk located just above the right ureteral orifice. Because the lesion was suspicious for at least lamina propria invasion, a single dose of mitomycin C was instilled after resection. Pathologic evaluation of the specimen was reported as grade 2 transitional cell carcinoma of the bladder with lamina propria invasion. Immunohistochemical staining with p53 and Ki-67 was performed for further evaluation.
authors.affiliation: Department of Urology, University of Ankara School of Medicine, Yildiz, Ankara, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Gülpinar
authors.forename: Tarkan
authors.initials: T
authors.lastname: Soygür
authors.forename: Sümer
authors.initials: S
authors.lastname: Baltaci
authors.forename: Murat
authors.initials: M
authors.lastname: Akand
authors.forename: Duygu
authors.initials: D
authors.lastname: Kankaya
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000601:surgery; D002648:Child; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery