title: Ocular lesions associated with Trypanosoma evansi in experimentally infected goats.
abstract: Ocular lesions associated with Trypanosoma spp. infection have been described in man and many animal species. However, loss of vision has not been demonstrated in humans presenting Chagas disease or in animals affected by different trypanosome species. In order to assess the possible ocular disorders caused by Trypanosoma evansi infection, six goats were inoculated with 1 x 10(5) T. evansi and maintained for 12 months and four goats were used as control. The inoculated animals became positive at serological and parasitological tests at 1-month post-inoculation and showed a subclinical course of the disease. Unilateral superficial corneal ulceration and retinochoroiditis were observed in two inoculated animals. Data from ocular neurologic examination and electroretinography showed no significant differences between inoculated and non-inoculated goats. It could be concluded that Trypanosoma evansi can produce ocular lesion but without apparent loss of vision in goats.
authors.affiliation: Veterinary Faculty, University of Las Palmas, 35416 Arucas, Las Palmas, Canary Islands, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Morales
authors.forename: Mónica
authors.initials: M
authors.lastname: de León
authors.forename: Manuel
authors.initials: M
authors.lastname: Morales
authors.forename: Francesca
authors.initials: F
authors.lastname: Dalla
authors.forename: Carlos
authors.initials: C
authors.lastname: Gutierrez
mesh_terms: D000818:Animals; D004596:Electroretinography / Q000379:methods / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000469:parasitology / Q000473:pathology*; D006041:Goats; D011897:Random Allocation; D012160:Retina / Q000473:pathology*; D012698:Serologic Tests / Q000662:veterinary; D014345:Trypanosoma; D014352:Trypanosomiasis / Q000473:pathology / Q000662:veterinary*