title: Malignant peripheral nerve sheath tumors of the head and neck: two cases and a review of the literature.
abstract: Malignant peripheral nerve sheath tumors are uncommon lesions that occasionally affect the head and neck. We describe 2 new cases of head and neck pathology. One tumor involved the parotid gland and resulted in erosion of the temporal bone, and the other affected the lower lip. A rapid diagnosis has significant implications for management because of the tumor's potential for aggressive behavior and its high rate of recurrence. To the best of our knowledge, lip involvement is rare and temporal bone involvement has not been previously described.
authors.affiliation: Department of Otolaryngology and Skull Base Surgery, Addenbrooke's NHS Trust, UK. devesa@doctors.org.uk
authors.forename: Pablo
authors.initials: P
authors.lastname: Martinez Devesa
authors.forename: Timothy E
authors.initials: TE
authors.lastname: Mitchell
authors.forename: Ian
authors.initials: I
authors.lastname: Scott
authors.forename: David A
authors.initials: DA
authors.lastname: Moffat
mesh_terms: D000328:Adult; D000792:Angiography; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008048:Lip Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018317:Nerve Sheath Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D010306:Parotid Gland / Q000601:surgery; D010307:Parotid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed