title: Meiotic crossing-over: obligation and interference.
abstract: During meiosis, crossing-over--the exchange of genetic material between maternal and paternal chromosomes--is stringently controlled to restrict the number of crossovers per chromosome pair. In this issue of Cell, Martini et al., (2006) report that the reduction of crossover-initiating events does not result in fewer crossovers. These results have important implications for our understanding of crossover control.
authors.affiliation: School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK. g.h.jones@bham.ac.uk
authors.forename: Gareth H
authors.initials: GH
authors.lastname: Jones
authors.forename: F Chris H
authors.initials: FC
authors.lastname: Franklin
mesh_terms: D003434:Crossing Over, Genetic; D006706:Homeostasis; D008540:Meiosis; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000502:physiology*