Initial study of two-phase laminar flow extraction chip for sample preparation for gas chromatography.
A sample preparation method for gas chromatography using a two-phase, laminar flow extraction PDMS/glass chip has been developed. A stable two-phase laminar interface was obtained by surface modification, and the organic extraction phase and the aqueous sample phase were separated effectively when the two-phase laminar flows exit the chip. Experiments were conducted on the chip to extract ephedrine from aqueous solution. Good reproducibility was obtained over the entire range of ephedrine concentration using the extraction chips (CV range 2.7%-4.5%). Effects of salt and solvent on extraction efficiency were studied.
Xiao
Hong
H
Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.
Liang
Dong
D
Liu
Guanchao
G
Guo
Min
M
Xing
Wanli
W
Cheng
Jing
J
D002849:Chromatography, Gas; D004809:Ephedrine / Q000032:analysis*; D046210:Microfluidic Analytical Techniques; D015203:Reproducibility of Results; D012997:Solvents / Q000737:chemistry
D012997:Solvents; D004809:Ephedrine