Plasma membrane calcium pumps in mouse olfactory sensory neurons.
We report here the presence of specific plasma membrane calcium pumps (PMCAs) in mouse olfactory sensory neurons. All 4 isoforms are present as shown by deconvolution microscopy, and the specific splice variants are identified by reverse transcriptase (RT)-polymerase chain reaction (PCR). The PMCAs are present on the cell body, dendrite, knob, and cilia, but the different isoforms of PMCAs are not identical in their distributions. The PMCAs are positioned to play a role in calcium clearance after stimulation.
Weeraratne
S Dilhan
SD
Department of Biology, University of Vermont, 109 Carrigan Drive, Burlington, VT 05405, USA.
Valentine
Megan
M
Cusick
Matthew
M
Delay
Rona
R
Van Houten
Judith L
JL
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D003712:Dendrites / Q000378:metabolism*; D051379:Mice; D018613:Microscopy, Confocal; D018034:Olfactory Receptor Neurons / Q000378:metabolism*; D053499:Plasma Membrane Calcium-Transporting ATPases / Q000378:metabolism*; D020033:Protein Isoforms / Q000737:chemistry / Q000648:ultrastructure; D020133:Reverse Transcriptase Polymerase Chain Reaction
D020033:Protein Isoforms; D053499:Plasma Membrane Calcium-Transporting ATPases