title: Two new monodesmosidic triterpene saponins from Gypsophila oldhamiana.
abstract: Two new monodesmosidic triterpene saponins were isolated from the roots of Gypsophila oldhamiana (Caryophyllaceae). Their structures were elucidated on the basis of spectral data to be quillaic acid, alpha-L-arabinopyranosyl-(1-->4)-alpha-L-arabinopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-fucopyranosyl ester (1), and vaccaric acid, beta-D-glucopyranosyl-(1-->3)-[beta-D-xylopyranosyl-(1-->4)]-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-fucopyranosyl ester (2). Compound 1 showed a significant enhancement of granulocyte phagocytosis in vitro.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang. Nanjing 210009, People's Repubic of China.
authors.forename: Jian-Guang
authors.initials: JG
authors.lastname: Luo
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Takaya
authors.forename: Masatake
authors.initials: M
authors.lastname: Niwa
mesh_terms: D000818:Animals; D029748:Caryophyllaceae / Q000737:chemistry*; D002478:Cells, Cultured; D004353:Drug Evaluation, Preclinical; D008213:Lymphocyte Activation / Q000187:drug effects; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry*; D013601:T-Lymphocytes / Q000187:drug effects; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D012503:Saponins; D014315:Triterpenes; C513999:quillaic acid arabinopyranosyl-1-4-arabinopyranosyl-1-3-xylopyranosyl-1-4-rhamnopyranosyl-1-2-fucopyranosyl ester; C514000:vaccaric acid glucopyranosyl-1-3-(xylopyranosyl-1-4)-rhamnopyranosyl-1-2-fucopyranosyl ester