Occupational manganese neurotoxicity provoked by hepatitis C.
Manganese neurotoxicity developed in a highly exposed worker after asymptomatic, moderate hepatic dysfunction from hepatitis C infection. Antiviral therapy was accompanied by resolution of increased blood manganese levels and neurologic improvement. Even asymptomatic hepatic dysfunction may impair manganese clearance and place highly exposed persons at risk for toxicity.
Schaumburg
Herbert H
HH
Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA. schaumbu@aecom.yu.edu
Herskovitz
Steven
S
Cassano
Victoria A
VA
D000328:Adult; D005260:Female; D006526:Hepatitis C / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D020149:Manganese Poisoning / Q000175:diagnosis* / Q000209:etiology*; D008669:Metallurgy; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects*