title: Surgical results in pediatric moyamoya disease: angiographic revascularization and the clinical results.
abstract: OBJECTIVE
  We retrospectively reviewed the pediatric patients with moyamoya disease (MMD) who underwent bypass surgery at our institution to compare the surgical results according to the surgical procedures.
  
  
  METHODS
  There were 24 total patients (age range: 2-15 years; mean age: 8.2 years). Twelve patients underwent encephalo-duro-arterio-synangiosis (EDAS) on 16 sides, 5 patients underwent encephalo-duro-arterio-myo-synangiosis (EDAMS) on 8 sides and 7 patients underwent combined superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis with EDAMS (STA-MCA-EDAMS) on 12 sides. The postoperative results were evaluated between 4 months and 5 years following surgery in terms of the angiographic revascularization and the clinical outcome.
  
  
  RESULTS
  EDAMS, regardless of the combined STA-MCA anastomosis, was significantly effective for achieving a good extent of the postoperative angiographic revascularization as compared with simple EDAS (P<0.05). STA-MCA-EDAMS tended to be better with respective to the relief of preoperative ischemic symptoms as compared with simple EDAS, although there was no significant statistical difference.
  
  
  CONCLUSIONS
  These results suggest that EDAMS with or without the combination of STA-MCA anastomosis was very useful for the formation of collateral circulation in comparison with simple EDAS for treating the pediatric patients with MMD, although these findings were not well correlated with the clinical outcomes.
authors.affiliation: Department of Neurosurgery, The Catholic University of Korea College of Medicine, Uijeongbu St. Mary's Hospital, 65-1 Kumoh-dong, Uijeongbu, Gyeonggi 480-130, Republic of Korea.
authors.forename: Dal-Soo
authors.initials: DS
authors.lastname: Kim
authors.forename: Seok-Gu
authors.initials: SG
authors.lastname: Kang
authors.forename: Do-Sung
authors.initials: DS
authors.lastname: Yoo
authors.forename: Pil-Woo
authors.initials: PW
authors.lastname: Huh
authors.forename: Kyoung Suok
authors.initials: KS
authors.lastname: Cho
authors.forename: Chun Kun
authors.initials: CK
authors.lastname: Park
mesh_terms: D000293:Adolescent; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000601:surgery; D002548:Cerebral Revascularization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D009072:Moyamoya Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D010043:Outcome and Process Assessment, Health Care; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D012189:Retrospective Studies