title: Canine renal failure syndrome in three dogs.
abstract: Three dead dogs were brought to the College of Veterinary Medicine, Kyungpook National University for study. Clinically, all the dogs showed emaciation, anorexia, depression, hemorrhagic vomiting and diarrhea for 7-10 days before death. All the clinical signs were first noted for about one month after feeding the dogs with commercial diets. At necropsy, all 3 dogs had severe renal damage with the same green-yellowish colored nephroliths in the renal pelvis. They also showed systemic hemorrhage and calcification of several organs, which might have been induced by uremia. Microscopically, necrosis, calcification and calculi were detected in the renal tubules, and especially in the proximal convoluted tubules and collecting ducts of the kidney. These findings were supportive of a mycotoxic effect, and especially on their kidneys. However, the precise cause of the toxic effect in these cases of canine renal failure could not be determined.
authors.affiliation: Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea.
authors.forename: Won Il
authors.initials: WI
authors.lastname: Jeong
authors.forename: Sun Hee
authors.initials: SH
authors.lastname: Do
authors.forename: Da Hee
authors.initials: DH
authors.lastname: Jeong
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Chung
authors.forename: Hai Jie
authors.initials: HJ
authors.lastname: Yang
authors.forename: Dong Wei
authors.initials: DW
authors.lastname: Yuan
authors.forename: Il Hwa
authors.initials: IH
authors.lastname: Hong
authors.forename: Jin Kyu
authors.initials: JK
authors.lastname: Park
authors.forename: Moon Jung
authors.initials: MJ
authors.lastname: Goo
authors.forename: Kyu Shik
authors.initials: KS
authors.lastname: Jeong
mesh_terms: D058186:Acute Kidney Injury / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000382:microbiology / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D008297:Male; D015651:Mycotoxicosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*