Anetoderma occurring after hepatitis B vaccination.
Anetoderma is an elastolytic disorder of unknown origin. To our knowledge, anetoderma secondary to hepatitis B immunization has been described only once in the literature, in two siblings vaccinated at the same time. We describe, what we believe to be an additional case of such a rare disorder in a 21-year-old man. He presented with white spots and papules on his neck, upper limbs and trunk, that had developed gradually within the last 6 years without any symptoms. The initial lesions were red macules, which gradually enlarged in size and number, becoming pale. Biopsy of a sack-like lesion revealed normal epidermis and a discrete mononuclear infiltrate throughout the dermis. Association of anetoderma with hepatitis B vaccination is speculated here, as suggested by history of vaccination two weeks prior to the onset of skin eruption and ruling out other possible causes of anetoderma.
Teixeira
Marta
M
Department of Dermatology, Hospital Geral de Santo Antonio, Porto, Portugal. martamotateixeira@mail.telepac.pt
Alves
Rosario
R
Canelhas
Aurea
A
Selores
Manuela
M
D000328:Adult; D002465:Cell Movement / Q000276:immunology; D003238:Connective Tissue / Q000276:immunology / Q000473:pathology*; D004547:Elastic Tissue / Q000276:immunology / Q000473:pathology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000473:pathology; D008297:Male; D012871:Skin Diseases / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology*
D017325:Hepatitis B Vaccines