[An overview of the pharmacokinetics and pharmacodynamics of rocuronium bromide].
For many years, much effort has been done to develop non-depolarizing neuromuscular blocking agents of rapid onset and short duration. It has been shown that rocuronium bromide is a nondepolarizing, steroidal muscle relaxant with fast onset and short-to-intermediate duration of action. In addition, rocuronium-induced neuromuscular blockade can be readily and consistently reversed following the administration of reversal agents. The pharmacology and pharmacodynamics of rocuronium bromide are summarized in this review.
Iwasaki
Hiroshi
H
Department of Anesthesiology and Critical Care, Asahikawa Medical College, Asahikawa 078-8510.
D000368:Aged; D000732:Androstanols / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D000762:Anesthesia Recovery Period; D002648:Child; D006801:Humans; D003473:Neuromuscular Nondepolarizing Agents / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D000077123:Rocuronium
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium