title: Endometrial disorders in patients with peritoneal serous papillary carcinoma.
abstract: BACKGROUND
  The purpose of this study was to evaluate the incidence rate of endometrial disease, particularly endometrial carcinoma, in patients with primary peritoneal serous papillary carcinoma (PSPC).
  
  
  METHODS
  Retrospective review of clinical and histological data from 32 women undergoing surgery (with hysterectomy) for stage III or IV PSPC.
  
  
  RESULTS
  Six patients underwent primary debulking surgery and 26 underwent interval debulking surgery after 3 or 4 courses of platinum-based chemotherapy. Six patients (18%) had endometrial disease (hyperplasia in four). Two patients had endometrioid adenocarcinoma of the uterine body (stage IA grade 1 in one case, and stage IB grade 1 in the other) associated with the PSPC.
  
  
  CONCLUSIONS
  Endometrial carcinoma of the uterine body may be associated with PSPC (6% cases in the present series). This result suggests that systematic hysterectomy should be performed at the time of debulking surgery in PSPC, even in the absence of peritoneal spread within pelvic cavity.
authors.affiliation: Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France.
authors.forename: Abdi
authors.initials: A
authors.lastname: Bafghi
authors.forename: Yaelle
authors.initials: Y
authors.lastname: Zafrani
authors.forename: Patricia
authors.initials: P
authors.lastname: Pautier
authors.forename: Catherine
authors.initials: C
authors.lastname: Lhommé
authors.forename: Pierre
authors.initials: P
authors.lastname: Duvillard
authors.forename: Damienne
authors.initials: D
authors.lastname: Castaigne
authors.forename: Chistine
authors.initials: C
authors.lastname: Haie-Meder
authors.forename: Philippe
authors.initials: P
authors.lastname: Morice
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D000369:Aged, 80 and over; D002291:Carcinoma, Papillary / Q000150:complications; D018284:Cystadenocarcinoma, Serous / Q000150:complications*; D004714:Endometrial Hyperplasia / Q000150:complications*; D016889:Endometrial Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000150:complications*; D012189:Retrospective Studies