title: [Complexities of "reversible posterior leukoencephalopathy syndrome"].
abstract: We report a case of reversible posterior leukoencephalopathy syndrome in a 50-year-old patient with severe untreated hypertension. Recent advances in magnetic resonance imaging (especially diffusion-weighted imaging) allow new pathopysiological insight: it was found that the resulting vasogenic edema was restricted neither to the posterior vascular territories nor to white matter. The apparent diffusion coefficient helps to differentiate between reversible vasogenic edema and cytotoxic edema, the latter indicating irreversible neuronal death.
authors.affiliation: Neurologische Klinik, Klinikum Grosshadern der LMU München, Marchioninistrasse 15, 81377, München. Simone.Herberger@med.uni-muenchen.de
authors.forename: S
authors.initials: S
authors.lastname: Herberger
authors.forename: J
authors.initials: J
authors.lastname: Linn
authors.forename: T
authors.initials: T
authors.lastname: Pfefferkorn
authors.forename: B
authors.initials: B
authors.lastname: Feddersen
authors.forename: T
authors.initials: T
authors.lastname: Göhringer
authors.forename: F
authors.initials: F
authors.lastname: Winkler
authors.forename: A
authors.initials: A
authors.lastname: Straube
authors.forename: A
authors.initials: A
authors.lastname: Danek
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D001929:Brain Edema / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D004359:Drug Therapy, Combination; D006261:Headache / Q000209:etiology; D006801:Humans; D020343:Hypertensive Encephalopathy / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D009483:Neuropsychological Tests
chemical_list: D000959:Antihypertensive Agents