title: Pedimune in recurrent respiratory infection and diarrhoea--the Indian experience--the pride study.
abstract: OBJECTIVE
  To evaluate the efficacy and tolerability of bovine colostrum in preventing recurrent episodes of upper respiratory tract infections and diarrhoea in children
  
  
  METHODS
  605 children (1-8 yrs) having recurrent episodes of upper respiratory tract infections or diarrhea received Bovine Colostrum (Pedimune) for 12 weeks. Total no of episodes of recurrent infections, hospitalization rate, overall well being and adverse events were assessed at every 4 weeks.
  
  
  RESULTS
  Episodes of URTI and diarrhoea reduced significantly by 91.19 % and 86.60% at the end of therapy respectively. High to average improvement in overall well-being in 96 % of the patients were found by pediatrician while overall well-being stated by the patient/care taker was very good to good in 90.56 % of the patients.
  
  
  CONCLUSIONS
  Bovine colostrum was highly effective in the prophylactic treatment of recurrent URTIs and diarrhea in reducing not only the episodes but also the hospitalization due to them.
authors.affiliation: Merck Ltd, Mumbai, India.
authors.forename: Kamlesh
authors.initials: K
authors.lastname: Patel
authors.forename: Rajiv
authors.initials: R
authors.lastname: Rana
mesh_terms: D002648:Child; D002675:Child, Preschool; D003126:Colostrum / Q000276:immunology*; D003967:Diarrhea / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006760:Hospitalization; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology*; D007194:India; D007223:Infant; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000276:immunology
chemical_list: D007155:Immunologic Factors