Characterization of a novel B(A) allele with BBBA type at the ABO blood group.
The ABO blood group is one of the main blood group systems, and it plays an important role in transfusion medicine and transplantation. To date, most of the many ABO subgroups with a weak expression of the A or B antigen on red blood cells have been elucidated to have specific molecular genetic background with respect to the ABO gene. The ABO*B(A) allele or CisAB allele is a type of dual ABO allele which can encode glycosyltransferases responsible for the conversion of H substance to both A and B antigen. We report here our characterization of a novel B(A) allele which differs from those reported previously.
Deng
Zhi-Hui
ZH
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China.
Yu
Qiong
Q
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China. yuqiong7867@yahoo.com.cn.
Liang
Yan-Lian
YL
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China.
Wang
Da-Ming
DM
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China.
Su
Yu-Qing
YQ
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China.
Wu
Guo-Guang
GG
ShenZhen Institute of Transfusion Medicine, Ni-Gang Xi Road, Mei-Gang Nan Street, ShenZhen, GuangDong, 518035, People's Republic of China.
D000017:ABO Blood-Group System / Q000235:genetics*; D000328:Adult; D000483:Alleles; D001788:Blood Grouping and Crossmatching; D003001:Cloning, Molecular; D005091:Exons / Q000235:genetics; D005838:Genotype; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics; D010375:Pedigree; D010641:Phenotype; D017422:Sequence Analysis, DNA
D000017:ABO Blood-Group System