title: Predictive value of transcranial sonography in the diagnosis of Parkinson's disease.
abstract: Transcanial sonography (TCS) is increasingly applied in the diagnosis of Parkinson's disease (PD), but investigator bias may influence the results of examination. Blinding the sonographer to the clinical diagnosis of 42 PD patients and 35 controls, we obtained a positive predictive value of 85.7% and a negative predictive value of 82.9% in the diagnosis of PD solely by interpreting the results of TCS, indicating that TCS is a valuable additional tool in the diagnosis of PD.
authors.affiliation: Hertie Institute for Clinical Brain Research, Tübingen, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Prestel
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Schweitzer
authors.forename: Anne
authors.initials: A
authors.lastname: Hofer
authors.forename: Thomas
authors.initials: T
authors.lastname: Gasser
authors.forename: Daniela
authors.initials: D
authors.lastname: Berg
mesh_terms: D000368:Aged; D004453:Echoencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D012016:Reference Values; D012680:Sensitivity and Specificity; D013378:Substantia Nigra / Q000000981:diagnostic imaging