title: [Intensity of lipid peroxidation in the kidneys in nephrotoxic acute renal failure (experimental study)].
abstract: Mercury chloride was injected cubcutaneously in rats to induce nephrotoxic acute renal failure (ARF). Renal dysfunction in ARF occurs under intensification of lipid peroxidation in the kidneys. Pretreatment with antioxidant ionol diminishes lipid peroxidation intensity in the kidneys in ARF and restricts the severity of renal dysfunction.
authors.forename: V S
authors.initials: VS
authors.lastname: Makarenko
authors.forename: N G
authors.initials: NG
authors.lastname: Zhiznevskaia
authors.forename: T I
authors.initials: TI
authors.lastname: Koltygina
authors.forename: V M
authors.initials: VM
authors.lastname: Gapanovich
authors.forename: E V
authors.initials: EV
authors.lastname: Makarenko
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000378:metabolism* / Q000517:prevention & control; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008627:Mercuric Chloride / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000975:Antioxidants; D002084:Butylated Hydroxytoluene; D008627:Mercuric Chloride