[Effect of protein synthesis inhibitors on sensitization of defence reaction and on cholinosensitivity of command neurons in Helix lucorum].
We studied influence of protein synthesis inhibitors on short-term sensitization of Helix escape reaction and potentiation cholinosensitivity in command neurons. Inhibitor of protein synthesis anisomycin does not prevent behavioral sensitization. Anisomycin and irreversible inhibitor of protein synthesis saporin change the dynamics of cholinosensitivity potentiation in command neurons. The results Suggest that investigated sensitization of Helix escape reaction does not require synthesis of new proteins.
Abramova
M S
MS
Moskvitin
A A
AA
Pivovarov
A S
AS
D000109:Acetylcholine / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D000841:Anisomycin / Q000008:administration & dosage / Q000494:pharmacology; D004558:Electric Stimulation; D004924:Escape Reaction / Q000187:drug effects*; D017952:Ganglia, Invertebrate / Q000187:drug effects; D006372:Helix, Snails / Q000187:drug effects* / Q000502:physiology; D000922:Immunotoxins / Q000008:administration & dosage / Q000494:pharmacology; D008564:Membrane Potentials; D009699:N-Glycosyl Hydrolases / Q000008:administration & dosage / Q000494:pharmacology; D009476:Neurons, Efferent / Q000187:drug effects / Q000502:physiology*; D010940:Plant Proteins / Q000008:administration & dosage / Q000494:pharmacology; D011500:Protein Synthesis Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D054789:Ribosome Inactivating Proteins, Type 1; D000076985:Saporins
D000922:Immunotoxins; D010940:Plant Proteins; D011500:Protein Synthesis Inhibitors; D054789:Ribosome Inactivating Proteins, Type 1; D000841:Anisomycin; D009699:N-Glycosyl Hydrolases; D000076985:Saporins; D000109:Acetylcholine