[Intensity of lipid peroxidation in the kidneys in nephrotoxic acute renal failure (experimental study)].
Mercury chloride was injected cubcutaneously in rats to induce nephrotoxic acute renal failure (ARF). Renal dysfunction in ARF occurs under intensification of lipid peroxidation in the kidneys. Pretreatment with antioxidant ionol diminishes lipid peroxidation intensity in the kidneys in ARF and restricts the severity of renal dysfunction.
Makarenko
V S
VS
Zhiznevskaia
N G
NG
Koltygina
T I
TI
Gapanovich
V M
VM
Makarenko
E V
EV
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000378:metabolism* / Q000517:prevention & control; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008627:Mercuric Chloride / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
D000975:Antioxidants; D002084:Butylated Hydroxytoluene; D008627:Mercuric Chloride