title: Therapeutic approach to tumors of the ampulla of Vater.
abstract: OBJECTIVE
  Indications for local resection for tumors of the ampulla of Vater have not been established. The present study evaluated suitable treatments for tumors of the papilla of Vater.
  
  
  METHODS
  Clinicopathological factors were reviewed for 53 patients with tumors of the ampulla of Vater treated between February 1993 and August 2003.
  
  
  RESULTS
  Of 53 patients, 41 were treated surgically. Local resection was performed in 7 of these 41 patients, with a histologically involved margin evident in 4 patients. Lymph node metastasis was identified in 20 patients who received radical resection, including 1 patient with pT1 cancer.
  
  
  CONCLUSIONS
  Given the presence of some positive surgical margins, local resection is indicated as a therapeutic approach to tumors of the papilla of Vater only for benign tumors or some malignant tumors that cannot undergo pancreaticoduodenectomy (PD).
authors.affiliation: Surgery Division, National Cancer Center Hospital East, Kashiwa City, Chiba, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Masaru
authors.initials: M
authors.lastname: Konishi
authors.forename: Toshio
authors.initials: T
authors.lastname: Nakagohri
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Takahashi
authors.forename: Taira
authors.initials: T
authors.lastname: Kinoshita
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000601:surgery*; D000328:Adult; D000368:Aged; D014670:Ampulla of Vater; D001706:Biopsy; D002277:Carcinoma / Q000175:diagnosis / Q000601:surgery*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003138:Common Bile Duct Neoplasms / Q000175:diagnosis / Q000601:surgery*; D003937:Diagnosis, Differential; D013505:Digestive System Surgical Procedures / Q000379:methods*; D019160:Endosonography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome