title: The use of benzodiazepines in palliative care.
abstract: BACKGROUND
  Benzodiazepines are widely used in palliative care, but few studies have attempted to study their use.
  
  
  OBJECTIVE
  To determine the frequency and nature of benzodiazepine prescribing in a palliative care setting.
  
  
  METHODS
  The notes of a consecutive series of 100 patients who had died or been discharged from the hospice were studied. Demographic, illness and prescription data were noted. The indication for the administration of benzodiazepines, their effectiveness and any adverse effects were recorded.
  
  
  RESULTS
  Notes were found on 93 patients. Some 54 (58%) were prescribed benzodiazepines either by the hospice or their General Practitioner. Younger patients and those on opioids or antipsychotics were more likely to be prescribed benzodiazepines. Most administration of benzodiazepines occurred within the last three weeks of life in response to symptoms of anxiety or less specific distress.
  
  
  CONCLUSIONS
  A relatively high proportion of patients was prescribed benzodiazepines. The role of benzodiazepines at different stages of palliative care merits further study.
authors.affiliation: Department of Psychological Medicine, Institute of Psychiatry, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK. m.henderson@iop.kcl.ac.uk
authors.forename: M
authors.initials: M
authors.lastname: Henderson
authors.forename: E
authors.initials: E
authors.lastname: MacGregor
authors.forename: N
authors.initials: N
authors.lastname: Sykes
authors.forename: M
authors.initials: M
authors.lastname: Hotopf
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001569:Benzodiazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000706:statistics & numerical data*
chemical_list: D001569:Benzodiazepines