Evaluation of methanol extract of mole crab Emerita asiatica for its pathological properties using mouse assay.
A The methanol extract of marine mole crab, Emerita asiatica was tested for its pharmacological property using mouse assay. The vital organs viz.heart and lungs showed oedema and degeneration of cardiac muscles, markedly congested blood vessels and haemorrhagic exudates involving entire alveolar parenchyma in the lungs. The extract is seemed to influence negatively on the structure and functions of heart and lungs and non site-specific changes in the brain of mice.
Yogamoorthi
A
A
Centre for Futures Studies, Pondicherry University, Pondicherry-605 014, India. yogapond@yahoo.com
Srikala
G
G
D000818:Animals; D033381:Anomura / Q000737:chemistry / Q000472:pathogenicity*; D001681:Biological Assay; D008168:Lung / Q000187:drug effects* / Q000473:pathology; D000432:Methanol; D051379:Mice; D009206:Myocardium / Q000473:pathology*; D014020:Tissue Extracts / Q000302:isolation & purification* / Q000494:pharmacology*
D014020:Tissue Extracts; D000432:Methanol