Palmar skin lesions reversed by propylthiouracil therapy.
Antithyroid thioureylene compounds such as propylthiouracil, methimazole, and thiamazole have been shown to have some beneficial effect in the treatment of plaque psoriasis in small clinical trials. An incidental finding is reported here on a patient with autoimmune polyendocrine syndrome type II who had dermatitis-like palmar skin lesions on the right palm, which was reversed with propylthiouracil therapy.
Malani
Ashok K
AK
Department of Internal Medicine, Heartlands Medical Center, St. Joseph, Missouri 64507, USA. drmalani@yahoo.com
D000328:Adult; D013956:Antithyroid Agents / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D005260:Female; D006801:Humans; D007642:Keratosis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications / Q000188:drug therapy*; D011441:Propylthiouracil / Q000627:therapeutic use*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications / Q000188:drug therapy
D013956:Antithyroid Agents; D011441:Propylthiouracil