title: The effects of microdose recombinant human erythropoietin regimens in athletes.
abstract: This study appraised the veracity of claims that athletes can evade doping controls by injecting microdoses of recombinant human erythropoietin (rHuEPO), which rapidly disappear from the circulation. We confirmed that microdosing can reduce the window of detection to as little as 12-18 hours post-injection, suggesting that authorities must adopt appropriate counter measures.
authors.forename: Michael
authors.initials: M
authors.lastname: Ashenden
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Varlet-Marie
authors.forename: Françoise
authors.initials: F
authors.lastname: Lasne
authors.forename: Michel
authors.initials: M
authors.lastname: Audran
mesh_terms: D004300:Doping in Sports; D004305:Dose-Response Relationship, Drug; D004921:Erythropoietin / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008657:Metabolic Clearance Rate; D011994:Recombinant Proteins; D012680:Sensitivity and Specificity; D013177:Sports
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin