[Ultrastructure of blood cells in children exposed to radiation in utero and resided in radionuclide contaminated zones].
The electron-microscopic examinations of lymphocytes and neutrophiles in circulating blood of children irradiated during intrauterine development and on posterior stages of ontogenesis were performed in dynamics after accidental period. Some changes in lymphocyte ultrastructure were revealed; namely the increased undulation of nuclear contours with dilated perinuclear space and some reconstructions of their cellular organoids (the increased density of mitochondrial matrix, crist disorganization, dilation of clear space in cisterns of cytoplasmic net, disorders in the structure of electron-dense granules). The peculiarities of neutrophile ultrastructure that are characterized by centre dilated perinuclear space, decrease in glycosomes, disorders in granular structure, vacuole presence, degradation of cytoplasm and nuclear hypersegmentation were determined.
Stepanova
E I
EI
Davidenko
O A
OA
Vdovenko
V Iu
VIu
D002588:Cesium Radioisotopes / Q000633:toxicity*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009504:Neutrophils / Q000528:radiation effects / Q000648:ultrastructure*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000097:blood* / Q000473:pathology; D011834:Radiation Monitoring; D011839:Radiation, Ionizing; D011848:Radioactive Pollutants / Q000633:toxicity*; D014455:Ukraine
D002588:Cesium Radioisotopes; D011848:Radioactive Pollutants