title: Physiological left ventricular hypertrophy or hypertrophic cardiomyopathy in an elite adolescent athlete: role of detraining in resolving the clinical dilemma.
abstract: The differentiation of physiological left ventricular hypertrophy (LVH) from hypertrophic cardiomyopathy (HCM) can prove challenging for even the most experienced cardiologists. The case is presented of a 17 year old elite swimmer who had electrocardiographic and echocardiographic features that were highly suggestive of HCM. However, indices of diastolic function were normal and cardiopulmonary exercise testing revealed high peak oxygen consumption in keeping with physiological LVH. To resolve the diagnostic dilemma, the patient underwent detraining for eight weeks, after which, there was complete resolution of the changes seen on electrocardiogram and echocardiogram, indicating physiological LVH rather than HCM.
authors.affiliation: Department of Cardiology, University Hospital of Lewisham, Lewisham High Street, London SE13 6LH, UK.
authors.forename: S
authors.initials: S
authors.lastname: Basavarajaiah
authors.forename: M
authors.initials: M
authors.lastname: Wilson
authors.forename: S
authors.initials: S
authors.lastname: Junagde
authors.forename: G
authors.initials: G
authors.lastname: Jackson
authors.forename: G
authors.initials: G
authors.lastname: Whyte
authors.forename: S
authors.initials: S
authors.lastname: Sharma
authors.forename: W O
authors.initials: WO
authors.lastname: Roberts
mesh_terms: D000293:Adolescent; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010806:Physical Education and Training / Q000379:methods*; D013550:Swimming / Q000502:physiology*