Synthesis, crystal structure, and DNA-binding study on the trinitrate{2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diisopropyl(acetamide))} gadolinium(III) complex.
A 2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diisopropyl(acetamide)) ligand (L) and its Gd(III) complex have been prepared and characterized. The crystal and molecular structure of the complex was determined by single-crystal X-ray diffraction. The interactions of complex with calf thymus DNA were investigated by UV-vis, fluorescence and viscosity measurements. Experimental results indicated that the complex can bind to DNA by intercalation modes. Its intrinsic binding constant is 1.03 x 10(6) M(-1).
Lei
Kewei
K
Department of Chemistry and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P.R. China.
Liu
Weisheng
W
Huang
Xiaofeng
X
Wang
Daqi
D
D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D005682:Gadolinium / Q000737:chemistry*; D008024:Ligands; D009566:Nitrates / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D013050:Spectrometry, Fluorescence
D008024:Ligands; D009566:Nitrates; D009942:Organometallic Compounds; C513992:trinitrato(2,2'-(2,3-naphthylenebis(oxy))bis(N,N-diisopropyl(acetamide)))gadolinium(III); D004247:DNA; D005682:Gadolinium