Kaposiform hemangioendothelioma of the mediastinum in a 7-month-old boy: a case report.
Kaposiform hemangioendothelioma is an aggressive vascular proliferation that has been recognized as a separate entity from other childhood vascular tumors. The authors present an unusual case of hemangioendothelioma arising in the mediastinum of a 7-month-old male infant with acute respiratory distress and Kasabach-Merritt syndrome. This patient with life-threatening lesion showed a dramatic response to interferon alfa-2a. This case had many histologic and clinical features consistent with kaposiform hemangioendothelioma.
Iwami
Daiji
D
Department of Pediatric Surgery, Iwate Prefectural Central Hospital, Morioka, 020-0066 Iwate, Japan. ikyoku@hospital.hachinohe.aomori.jp
Shimaoka
Satoru
S
Mochizuki
Izumi
I
Sakuma
Tsutomu
T
D000402:Airway Obstruction / Q000209:etiology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006390:Hemangioendothelioma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011994:Recombinant Proteins; D012135:Respiratory Sounds / Q000209:etiology
D000970:Antineoplastic Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins