title: [Study on risk factors of sporadic hepatitis E virus cases in some districts of Shanghai].
abstract: OBJECTIVE
  To study the risk factors of acute sporadic hepatitis E virus (HEV) cases and to analyze its partial sequence in some districts of Shanghai.
  
  
  METHODS
  30 blood samples were collected from the acute sporadic HEV cases in 2003-2004 and the RT-nPCR method was applied to obtain the sequence of HEV in these cases. Meanwhile, a 1:2 case-control study was used to identify risk factors in the process of sporadic HEV infection in these regions of Shanghai.
  
  
  RESULTS
  Data from the sequential analysis showed that HEV of the sporadic cases belonged to HEV genotype IV. Finding from the case-control study implicated that the housing condition, outside eating history, especially seafoods (OR = 7.048) played an important role in the infection of HEV. Results from multiple logistic regression showed that eating raw seafoods appeared to be one of the risk factors of HEV infection.
  
  
  CONCLUSIONS
  HEV sequences isolated from the sporadic cases of HEV in some districts of Shanghai belonged to HEV genotype IV. Foods, especially seafood, were the risk factors in the infection of HEV.
authors.affiliation: Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
authors.forename: Yan-ting
authors.initials: YT
authors.lastname: Li
authors.forename: Yi-yi
authors.initials: YY
authors.lastname: Zhu
authors.forename: Wei-guo
authors.initials: WG
authors.lastname: Shen
authors.forename: Ai-xiang
authors.initials: AX
authors.lastname: Zhang
authors.forename: Jian-ming
authors.initials: JM
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Ren
authors.forename: Guo-ping
authors.initials: GP
authors.lastname: Yuan
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: Gu
mesh_terms: D000208:Acute Disease; D016022:Case-Control Studies; D002681:China; D005506:Food Contamination; D005838:Genotype; D016751:Hepatitis E / Q000453:epidemiology* / Q000209:etiology; D016752:Hepatitis E virus / Q000235:genetics*; D006798:Housing; D006801:Humans; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D017747:Seafood