[The consequence of epinephrine (adrenaline) overdose].
Epinephrine is an adrenergic agonist used to treat bronchospasm, anaphylactic reactions, bradycardia, cardiac arrest, and hypotension. Its toxicity is usually caused by iatrogenic errors. In overdose there is a typical rapid onset of agitation, hypertension, tachycardia, and dysrhythmias. This review article focuses on the causes of overdose, signs and symptoms, treatment and expected course, and prognosis of this iatrogenic pathology.
Reingardiene
Dagmara
D
Clinic of Intensive Therapy, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania.
D000322:Adrenergic Agonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000707:Anaphylaxis / Q000188:drug therapy; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001919:Bradycardia / Q000188:drug therapy; D001986:Bronchial Spasm; D062787:Drug Overdose; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006323:Heart Arrest / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy; D007022:Hypotension / Q000188:drug therapy; D007049:Iatrogenic Disease; D011379:Prognosis; D011654:Pulmonary Edema / Q000139:chemically induced / Q000188:drug therapy; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000188:drug therapy; D013610:Tachycardia / Q000139:chemically induced
D000322:Adrenergic Agonists; D004837:Epinephrine