title: Gallbladder carcinoma late metastases and incisional hernia at umbilical port site after laparoscopic cholecystectomy.
abstract: A potentially serious complication of laparoscopic cholecystectomy is the inadvertent dissemination of unsuspected gallbladder carcinoma. There are increasing reports of seeding of tumor at the trocar sites following laparoscopic cholecystectomy in patients with unexpected or inapparent gallbladder carcinoma. Although the mechanism of the abdominal wall recurrence is still unclear, laparoscopic handling of the tumor, perforation of the gallbladder, and extraction of the specimen without an endobag may be risk factors for the spreading of malignant cells. The Authors report the case of late development of umbilical metastasis after laparoscopic cholecystectomy; the presence of an incisional hernia and the finding of a stone in subcutaneous tissue demonstrate the diffusion of tumor cells into subcutaneous tissue during the extraction of gallbladder. The patient underwent an excision of the metastases. She is disease free two years after surgical treatment.
authors.affiliation: Dipartimento di Chirurgia Generale, urgenza e trapianti d'organo, Università degli Studi di Palermo.
authors.forename: A
authors.initials: A
authors.lastname: Ciulla
authors.forename: G
authors.initials: G
authors.lastname: Romeo
authors.forename: G
authors.initials: G
authors.lastname: Genova
authors.forename: G
authors.initials: G
authors.lastname: Tomasello
authors.forename: G
authors.initials: G
authors.lastname: Agnello
authors.forename: Gaetano
authors.initials: G
authors.lastname: Cstronovo
mesh_terms: D000008:Abdominal Neoplasms / Q000556:secondary* / Q000601:surgery; D034861:Abdominal Wall / Q000601:surgery; D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000368:Aged; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000601:surgery; D046449:Hernia, Abdominal / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D009366:Neoplasm Seeding; D013526:Surgical Mesh; D013997:Time Factors; D014057:Tomography, X-Ray Computed