title: Duodenal interdigestive migrating motor complex in patients 5 years or more after pylorus-preserving gastrectomy for early gastric cancer.
abstract: BACKGROUND
  We investigated the relationship between interdigestive migrating motor complex, phase III (IMMC-pIII) and postoperative quality of life (QOL) in pylorus-preserving gastrectomy (PPG) patients.
  
  
  METHODS
  A total of 40 patients (26 men and 14 women; average age 59.4 years) 5 to 7.5 years after PPG for early gastric cancer (Billroth I) (average 6 years and 3 months) were divided into two groups according to the occurrence of IMMC-pIII from the duodenum, and their postoperative quality of life (QOL) was compared.
  
  
  RESULTS
  As for appetite, "No change compared with before operation" was significantly more frequent in the IMMC-pIII positive group compared with the negative group (P=0.0002). Food consumption per meal compared with normal; "80% or more" was significantly more frequent in the IMMC-pIII positive group than the negative group (P=0.0002). Body weight loss during 5 years after surgery; "6 kg or more" was significantly more frequent in the IMMC-pIII negative group than the positive group (P=0.0002). Early dumping symptoms did not occur in any patients of either group. Reflux esophagitis and nausea; no patients in the IMMC-pIII positive group experienced these symptoms, which was significantly different from the negative group (P=0.0018). Abdominal pain occurred but was significantly less frequent in the IMMC-pIII positive group than in the negative group (P=0.0023). Epigastric fullness occurred but was less frequent in the IMMC-pIII positive group compared with the negative group (P<0.0001). Gastric stasis of the remnant stomach was significantly more frequent in the IMMC-pIII negative group than in the positive group (P<0.0001). Gholelithiasis was significantly more frequent in the IMMC-pIII negative group than in the positive group (P=0.0119).
  
  
  CONCLUSIONS
  These results showed more satisfactory QOL in the IMMC-PIII positive group than in the negative group.
authors.affiliation: Department of Surgery, Nippon Dental University School of Dentistry at Tokyo, 2-3-16 Fujimi, Chiyoda-ku, Tokyo, 102-8158, Japan.
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Tomita
authors.forename: Tugumichi
authors.initials: T
authors.lastname: Koshinaga
authors.forename: Taro
authors.initials: T
authors.lastname: Ikeda
authors.forename: Shigeru
authors.initials: S
authors.lastname: Fujisaki
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Tanjoh
mesh_terms: D004386:Duodenum / Q000503:physiopathology; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016065:Myoelectric Complex, Migrating / Q000502:physiology*; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011708:Pylorus / Q000601:surgery; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000503:physiopathology* / Q000601:surgery*; D013997:Time Factors