title: Single-band mucosectomy for granular cell tumor of the esophagus: safe and easy technique.
abstract: BACKGROUND
  Mucosectomy involves resection of a digestive wall fragment that frequently removes a part or even all of the submucosal mass. The single-band mucosectomy technique was used to remove a granular cell tumor (GCT) of the esophagus. Only 3% of GCTs, which are relatively uncommon neoplasms, arise in the esophagus. Ultrasonography has allowed for more frequent recognition and better definition of this disease. Until recently, surgical resection of the esophagus has been the only treatment alternative to endoscopic surveillance. Endoscopic techniques such as mucosal resection (EMR), laser, and argon plasma have been proposed as safe and effective alternatives to surgery. However, to date, only a few reports of these endoscopic techniques have been published. This study aimed to evaluate the safety and feasibility of single-band mucosectomy for removing a GCT of the esophagus.
  
  
  METHODS
  Six patients (1 man and 5 women; mean age, 45 years) with a GCT were studied between January 2000 and May 2004. They underwent EMR after endoscopic ultrasonography.
  
  
  RESULTS
  The EMR was performed with a diathermic loop after injection of saline solution into the esophageal wall. Only one session was necessary for removal of the tumor from all 6 patients, and no complication was observed. During a mean clinical endoscopic follow-up period of 36 months, no recurrences, scars, or stenoses were observed.
  
  
  CONCLUSIONS
  These findings show EMR to be a safe and effective technique that allows complete removal of GCTs. Furthermore, this technique provides tissue for a definitive pathologic diagnosis, which laser and argon plasma do not provide. We recommend EMR as the treatment of choice for GCTs after an accurate ultrasonographic evaluation.
authors.affiliation: Istituto Oncologico Veneto (IOV), via Giogtinian 12, Padova, 35100, Italy. giorgio.battaglia@unipd.it
authors.forename: G
authors.initials: G
authors.lastname: Battaglia
authors.forename: S
authors.initials: S
authors.lastname: Rampado
authors.forename: P
authors.initials: P
authors.lastname: Bocus
authors.forename: E
authors.initials: E
authors.lastname: Guido
authors.forename: G
authors.initials: G
authors.lastname: Portale
authors.forename: E
authors.initials: E
authors.lastname: Ancona
mesh_terms: D000328:Adult; D004564:Electrocoagulation / Q000295:instrumentation; D004724:Endoscopy / Q000009:adverse effects; D019160:Endosonography; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D004947:Esophagus / Q000000981:diagnostic imaging / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D016586:Granular Cell Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000000981:diagnostic imaging / Q000601:surgery; D009339:Needles; D016896:Treatment Outcome