title: Highly enantioselective synthesis of beta-amino alcohols.
abstract: [reaction: see text] N,N-Dialkyl-beta-amino alcohols derived from alpha-amino acids can be rearranged enantiospecifically by using TFAA/Et3N/NaOH to give 1,2-amino alcohols with enantiomeric excess up to 99%.
authors.affiliation: Laboratoire de Chimie Organique, associé au CNRS, Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI), 10 rue Vauquelin, 75231 Paris Cedex 05, France.
authors.forename: Thomas-Xavier
authors.initials: TX
authors.lastname: Métro
authors.forename: Jérôme
authors.initials: J
authors.lastname: Appenzeller
authors.forename: Domingo Gomez
authors.initials: DG
authors.lastname: Pardo
authors.forename: Janine
authors.initials: J
authors.lastname: Cossy
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D000605:Amino Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D000605:Amino Alcohols