Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea.
Five new monoterpene glycosides, rhodiolosides A-E (1-5), were isolated from the roots of Rhodiola rosea (Crassulaceae). Their structures were elucidated as (2E,6E,4R)-4,8-dihydroxy-3,7-dimethyl-2,6-octadienyl beta-D-glucopyranoside (1), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl alpha-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside (2), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranoside (3), (2E,4R)-4,7-dihydroxy-3,7-dimethyl-2-octenyl beta-D-glucopyranoside (4), and (2E)-7-hydroxy-3,7-dimethyl-2-octenyl alpha-L-arabinopyranosyl(1-->6)-beta-D-glucopyranoside (5), on the basis of various spectroscopic analyses and chemical degradation.
Ma
Guizhi
G
College of Pharmacy, Xinjiang Medical University, 8 Xinyi Road, Urumki 830054, P.R. China.
Li
Wei
W
Dou
Deqiang
D
Chang
Xiaolong
X
Bai
Hong
H
Satou
Tadaaki
T
Li
Jun
J
Sun
Dianjia
D
Kang
Tingguo
T
Nikaido
Tamotsu
T
Koike
Kazuo
K
D002240:Carbohydrate Sequence; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005960:Glucosides / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D029771:Rhodiola / Q000737:chemistry*
D005960:Glucosides; D006027:Glycosides; D039821:Monoterpenes; D010636:Phenols; C009172:rhodioloside