Increase in catheter insertion-site infections associated to the introduction of a substandard competitive antiseptic.
The introduction of low-cost competitive antiseptic products may offer savings, but, unfortunately, their quality control is poor in many developing countries. The use of a new brand of idopovidone solution, used routinely for catheter insertion-site cleaning, was associated with a 55% increase in catheter insertion-site infection per 100 active catheters, returning to usual after the product was recalled. The new brand of iodopovidone solution had less free iodine (.76%) and lower pH (2.7) than required by local standards (pH 3-6.5). Use of substandard antiseptics in developing countries, because of poor quality control, is a risk for patients and results in increased health services expenses and burden of work.
Volkow
Patricia
P
Instituto Nacional de Cancerología, México City, Mexico. volkow@perezpadilla-volkow.com.mx
Sandoval
Silvia
S
Campos
Angeles Martinéz
AM
Gutiérrez
Margarita
M
de Romero
Cecilia
C
Viana Aguiluz
José Joaquín
JJ
Perez Padilla
Jose Rogelio
JR
D000891:Anti-Infective Agents, Local / Q000592:standards; D002408:Catheters, Indwelling / Q000009:adverse effects* / Q000382:microbiology; D015331:Cohort Studies; D003428:Cross Infection / Q000209:etiology*; D006801:Humans; D017053:Infection Control / Q000379:methods; D011206:Povidone-Iodine / Q000592:standards
D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine