New diterpene glycosides of the fungus Acremonium striatisporum isolated from a sea cucumber.
Three new diterpene glycosides, virescenosides V (1), W (2), and X (3) have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix. Their structures have been elucidated on the basis of high resolution mass spectrometry, 1D and 2D NMR (1H, 13C, DEPT, COSY 45, COSY RCT, HSQC, HMBC, and NOESY spectra) as 19-O-beta-D-altropyranosyl-7-oxo-isopimara-8(14),15-diene-2alpha,3beta-diol (1), 19-O-beta-D-altropyranosyl-isopimara-7,15-diene-2 alpha,3 beta,6 alpha-triol (2), and 19-O-beta-D-altropyranosyl-isopimara-8,15-diene-2 alpha,3 beta,7 alpha-triol (3).
Afiyatullov
Shamil Sh
SSh
Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Vladivostok 22, Russian Federation.
Kalinovsky
Anatoly I
AI
Pivkin
Mikhail V
MV
Dmitrenok
Pavel S
PS
Kuznetsova
Tatyana A
TA
D000164:Acremonium / Q000737:chemistry*; D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D012616:Sea Cucumbers / Q000382:microbiology*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
D004224:Diterpenes; D006027:Glycosides