Uropathogenic Escherichia coli strains generally lack functional Trg and Tap chemoreceptors found in the majority of E. coli strains strictly residing in the gut.
The prevalence and function of four chemoreceptors, Tsr, Tar, Trg, and Tap, were determined for a collection of uropathogenic, fecal-commensal, and diarrheagenic Escherichia coli strains. tar and tsr were present or functional in nearly all isolates. However, trg and tap were significantly less prevalent or functional among the uropathogenic E. coli strains (both in 6% of strains) than among fecal-commensal strains (both in > or =50% of strains) or diarrheal strains (both in > or =75% of strains) (P < 0.02).
Lane
M Chelsea
MC
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
Lloyd
Amanda L
AL
Markyvech
Tiffany A
TA
Hagan
Erin C
EC
Mobley
Harry L T
HL
D000596:Amino Acids / Q000378:metabolism; D001431:Bacteriological Techniques; D001483:Base Sequence; D002633:Chemotaxis; D004926:Escherichia coli / Q000378:metabolism / Q000502:physiology*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D005260:Female; D005798:Genes, Bacterial / Q000235:genetics; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D011956:Receptors, Cell Surface / Q000235:genetics / Q000378:metabolism*; D016415:Sequence Alignment; D014508:Urea / Q000378:metabolism; D014552:Urinary Tract Infections / Q000382:microbiology*
D000596:Amino Acids; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D011956:Receptors, Cell Surface; C067124:Tap protein, E coli; C041476:Trg protein, E coli; D014508:Urea