Subtype selective tetracycline agonists and their application for a two-stage regulatory system.
Berens
Christian
C
Department of Microbiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Staudtstrasse 5, 91058 Erlangen, Germany.
Lochner
Susanne
S
Löber
Stefan
S
Usai
Igor
I
Schmidt
Andreas
A
Drueppel
Lars
L
Hillen
Wolfgang
W
Gmeiner
Peter
P
D004318:Doxycycline / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D049409:Luciferases, Firefly / Q000235:genetics / Q000378:metabolism; D049410:Luciferases, Renilla / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D015394:Molecular Structure; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics*; D013752:Tetracycline / Q000819:agonists / Q000737:chemistry / Q000494:pharmacology*; D013754:Tetracyclines / Q000737:chemistry; D015534:Trans-Activators / Q000235:genetics; D015533:Transcriptional Activation / Q000187:drug effects*
D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; D013754:Tetracyclines; D015534:Trans-Activators; C034811:tetracycline resistance-encoding transposon repressor protein; C016229:4-epianhydrotetracycline; D049410:Luciferases, Renilla; D049409:Luciferases, Firefly; D013752:Tetracycline; D004318:Doxycycline