Spectrophotometric determination of the stability of an ampicillin-dicloxacillin suspension.
The degradation rate constants for ampicillin and for dicloxacillin in the suspension filtrate, and their solubility coefficients (at 25 degrees C) were determined by spectrophotometry employing a multicomponent computer program. The shelf life of the ampicillin-dicloxacillin suspension was then determined in terms of the stability of ampicillin, the least stable component.
Girona
V
V
Departmento de Físico-Química Aplicada, Facultad de Farmacia, Universidad de Barcelona, Núcleo Universitario de Pedralbes, 08028 Barcelona, Spain.
Pacareu
C
C
Riera
A
A
Pouplana
R
R
Castillo
M
M
Bolòs
J
J