Ion-pairing detection technique in reversed-phase high-performance liquid chromatography of drugs and related compounds.
The principles and practice of UV-detection methods based on the ion-pairing technique are discussed with respect to reversed-phase high-performance liquid chromatography. The detection of amino acids, aliphatic alcohols and vitamins is described together with the rationale for optimizing sensitivity of detection in using the ion-pairing technique for pharmaceutical analysis.
Crommen
J
J
Laboratoire d'Analyse des Médicaments, Institut de Pharmacie, Université de Liège, rue Fusch 5, B-4000 Liège, Belgium.