title: Hypertension and the pregnancy complicated by diabetes.
abstract: Diabetes is a frequent complication of pregnancy. Type 1 diabetes is associated with an increased incidence of preeclampsia and pregnancy-induced hypertension. When renal dysfunction is present, the incidence of these complications is remarkably increased. White's class, poor glycemic control during the first half of pregnancy, and early blood pressure elevation are also independent risk factors for developing preeclampsia. Whether gestational diabetes increases the background incidence of preeclampsia is still debated. Because therapeutic interventions such as low-dose aspirin and antioxidants have not been shown to be effective, preventive measures rely on tight blood glucose control, as well as adequate blood pressure treatment.
authors.affiliation: Diabetes in Pregnancy Unit, Department of Obstetrics and Gynecology, Center of Medical Education and Clinical Research (C.E.M.I.C.) University, Av. Galván 4102, Buenos Aires, Argentina. gleguizamon@cemic.edu.ar
authors.forename: Gustavo F
authors.initials: GF
authors.lastname: Leguizamón
authors.forename: Natalia P
authors.initials: NP
authors.lastname: Zeff
authors.forename: Alberto
authors.initials: A
authors.lastname: Fernández
mesh_terms: D048909:Diabetes Complications / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D016640:Diabetes, Gestational / Q000453:epidemiology; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology / Q000503:physiopathology*