title: [The clinical course of microalbumiuria in 4 burn patients].
abstract: BACKGROUND
  In burn patients, microvascular permeability is increased. It is difficult to decide the time to administer albumin because it may induce pulmonary edema in the re-filling period. One report shows that microalbuminuria is correlated with endothelial injury and systemic microvascular permeability.
  
  
  METHODS
  We measured urinary albumin/creatinine ratio (ACR) in 4 burn patients for 48 hours after injury.
  
  
  RESULTS
  In all patients, ACR was elevated in the early period after injury. Moreover, ACR in 2 severe burn patients with burn total body area of over 30% was above the normal range.
  
  
  CONCLUSIONS
  The present results show that ACR seems to be correlated with the level of microvascular permeability in 4 burn patients. We conclude that ACR may be a useful indicator to decide the time to administer albumin to a burn patient. However, further investigation is required to decide the threshold value of ACR in a severe burn patient whose ACR are kept above the normal range in the long-term.
authors.affiliation: Department of Anesthesia, Nagasaki Rousai Hospital, Sasebo 857-0134.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ando
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Terao
authors.forename: Kazunori
authors.initials: K
authors.lastname: Yamashita
authors.forename: Arihiro
authors.initials: A
authors.lastname: Fujinaga
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tanabe
authors.forename: Makoto
authors.initials: M
authors.lastname: Fukusaki
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000652:urine*; D002056:Burns / Q000652:urine*; D002199:Capillary Permeability; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D003404:Creatinine