Means used for terrestrial rabies elimination in France and policy for rabies surveillance in case of re-emergence.
In France, the first case of wildlife rabies was detected in 1968, with the red fox (Vulpes vulpes) as reservoir and vector of terrestrial rabies. The last case was reported at the end of 1998. The maximum infected area amounted to 140,000 km2 in 1989 with a record number of 4,213 infected wild and domestic animals. The contaminated areas included various landscapes such as low populated farming areas and low mountainous areas as well as very densely populated areas and industrial areas contiguously urbanised. Oral vaccination of wildlife against rabies was implemented in 1986 and 1987 on limited areas treated by hand distribution and then helicopter distribution was implemented in 1988. The control of wildlife rabies was centralised at the country level in one institute for elaboration of baiting strategies, rabies surveillance network, laboratory investigations such as tetracycline and serological testing, vaccine titration and rabies diagnosis. Oral vaccination campaigns were organised in spring and in autumn by dropping annually 40 baits/km2. The following vaccine baits were used: SAD B19 from 1986 to 1992, SAG1/SAG2 from 1990 to 2003 and VRG from 1989 to 2003. A cost analysis study of the system of oral vaccination implemented in France demonstrated that it is beneficial compared to the traditional expenses of rabies control. Animal rabies prophylaxis has been progressively adapted to the disease free status of the country; the surveillance network for rabies is still working and an emergency procedure is in place in the event of a re-emergence of the disease in the context of high density fox populations.
Cliquet
F
F
WHO Collaborating Centre for Research and Management in Zoonoses Control, OIE Reference Laboratory for Rabies, AFSSA, Malzéville, France. f.cliquet@afssa.fr
Combes
B
B
Barrat
J
J
D000284:Administration, Oral; D000818:Animals; D000835:Animals, Wild / Q000821:virology; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000517:prevention & control* / Q000662:veterinary; D005589:Foxes / Q000821:virology; D005602:France; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control* / Q000662:veterinary; D011819:Rabies Vaccines / Q000494:pharmacology*; D012189:Retrospective Studies; D014611:Vaccination / Q000331:legislation & jurisprudence* / Q000662:veterinary
D011819:Rabies Vaccines