title: Straight-chain fatty acids are dispensable in the myxobacterium Myxococcus xanthus for vegetative growth and fruiting body formation.
abstract: Inactivation of the MXAN_0853 gene blocked the production in Myxococcus xanthus of straight-chain fatty acids which otherwise represent 30% of total fatty acids. Despite this drastic change in the fatty acid profile, no change in phenotype could be observed, which contrasts with previous interpretations of the role of straight-chain fatty acids in the organism's development.
authors.affiliation: Institut für Pharmazeutische Biotechnologie, Universität des Saarlandes, P.O. Box 151150, 66041 Saarbrücken, Germany. h.bode@mx.uni-saarland.de
authors.forename: Helge B
authors.initials: HB
authors.lastname: Bode
authors.forename: Michael W
authors.initials: MW
authors.lastname: Ring
authors.forename: Dale
authors.initials: D
authors.lastname: Kaiser
authors.forename: Anna C
authors.initials: AC
authors.lastname: David
authors.forename: Reiner M
authors.initials: RM
authors.lastname: Kroppenstedt
authors.forename: Gertrud
authors.initials: G
authors.lastname: Schwär
mesh_terms: D015099:3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / Q000235:genetics / Q000378:metabolism; D005227:Fatty Acids / Q000096:biosynthesis / Q000502:physiology*; D009154:Mutation; D016941:Myxococcus xanthus / Q000254:growth & development* / Q000378:metabolism
chemical_list: D005227:Fatty Acids; C077402:3-ketoacyl-acyl carrier protein synthase III; D015099:3-Oxoacyl-(Acyl-Carrier-Protein) Synthase