Nano DCPA-whisker composites with high strength and Ca and PO(4) release.
The main challenges facing composite restorations are secondary caries and bulk fracture. The objective of this study was to develop nano DCPA (dicalcium phosphate anhydrous)-whisker composites with high strength and Ca and PO(4) ion release to combat caries. Flexural strength for the nano DCPA-whisker composites at a nano DCPA:whisker mass ratio of 1:2 ranged from (148 +/- 9) MPa to (167 +/- 23) MPa, significantly higher than the (103 +/- 32) MPa of an inlay/onlay commercial control composite without Ca-PO(4) release. The nano DCPA-whisker composite released PO(4) to a concentration of (1.95 +/- 0.13) mmol/L and Ca of (0.68 +/- 0.05) mmol/L. Compared with previous conventional Ca- and PO(4)-releasing composites, the nano DCPA-whisker composites had strengths two-fold higher, and released comparable or higher levels of Ca and PO(4). In conclusion, combining nano-DCPA with whiskers yielded novel composites that released high levels of Ca and PO(4) requisite for remineralization. These high-strength composites may provide a unique combination of stress-bearing and caries-inhibiting capabilities.
Xu
H H K
HH
Building 224, Room A-153, Stop 8546, Paffenbarger Research Center, American Dental Association Foundation, Gaithersburg, MD 20899-8546, USA.hockin.xu@nist.gov
Sun
L
L
Weir
M D
MD
Antonucci
J M
JM
Takagi
S
S
Chow
L C
LC
Peltz
M
M
D000704:Analysis of Variance; D002118:Calcium / Q000032:analysis; D002130:Calcium Phosphates / Q000737:chemistry; D017554:Carbon Compounds, Inorganic / Q000737:chemistry; D002327:Cariostatic Agents / Q000032:analysis; D003188:Composite Resins / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods; D003799:Dental Stress Analysis; D008422:Materials Testing; D008689:Methacrylates; D049329:Nanostructures; D010710:Phosphates / Q000032:analysis; D018583:Pliability; D017655:Silicon Compounds / Q000737:chemistry; D014961:X-Ray Diffraction
D002130:Calcium Phosphates; D017554:Carbon Compounds, Inorganic; D002327:Cariostatic Agents; D003188:Composite Resins; D008689:Methacrylates; D010710:Phosphates; D017655:Silicon Compounds; C005044:hydroxyethyl methacrylate; C485829:calcium phosphate, dibasic, anhydrous; D002118:Calcium; C022088:silicon carbide