[The advances in the neuropathology of sudden infant death syndrome].
Sudden infant death syndrome is known as sudden death in 12 months postnatal without obvious cause, the cause of death and differential diagnosis of still couldn't be indefinite so far. In this paper, the recent studies on the SIDS neuropathology using immunohisto-chemical technology were reviewed in order to suggest the lethal patho-physiologic derangement or mechanism in SIDS involves dysfunction of sleep-related cardio-respiratory homeostatic controls or failure to arouse. Thus the main cause of SIDS lies in central nerve system, but not unique cause.
Jin
Bo
B
West China Preclinical and Forensic College, Sichuan University, Chengdu 610041, China. wanghy11@163.com
Huang
Rui-Run
RR
Bai
Peng
P
Liao
Zhi-Gang
ZG
D001921:Brain / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D001933:Brain Stem / Q000378:metabolism / Q000473:pathology; D002490:Central Nervous System / Q000473:pathology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000378:metabolism / Q000473:pathology; D018840:HSP70 Heat-Shock Proteins; D006801:Humans; D000860:Hypoxia / Q000378:metabolism / Q000503:physiopathology; D007150:Immunohistochemistry; D007223:Infant; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D011506:Proteins / Q000378:metabolism; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D013398:Sudden Infant Death / Q000209:etiology / Q000473:pathology*
D018840:HSP70 Heat-Shock Proteins; D011506:Proteins; D016760:Proto-Oncogene Proteins c-fos; C050087:oxygen-regulated proteins