Ion-pair liquid chromatographic assay of angiotensin-converting enzyme activity.
A rapid and specific high-performance liquid chromatographic assay for the quantitative determination of angiotensin-converting enzyme activity is described. Hippuryl-L-histidyl-L-leucine (Hip-His-Leu) is used as substrate and the released hippuric acid is measured. The procedure is accurate and precise and no extraction is required.
Maurich
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V
Istituto di Tecnica Farmaceutica, Università di Trieste, 34100 Trieste, Italy.
Pitotti
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Vio
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Mamolo
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MG