title: Early aseptic loosening of a total knee arthroplasty due to Gore-Tex particle-induced osteolysis.
abstract: Anterior cruciate ligament reconstruction with the use of synthetic graft material has been used as an alternative to biologic grafts. The use of these grafts has largely been abandoned in reconstruction of the anterior cruciate ligament because of mechanical failure of the graft and production of wear debris leading to synovitis and recurrent effusions. This article presents a case of early, extensive periprosthetic osteolysis around a total knee arthroplasty associated with wear debris from retained fragments of a Gore-Tex (WL Gore and associates, Inc, Flagstaff, Ariz) (polytetrafluoroethylene) anterior cruciate ligament graft.
authors.affiliation: University Orthopedic Specialists, Tucson, Arizona.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Miller
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Peters
authors.forename: Bryce
authors.initials: B
authors.lastname: Allen
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D011138:Polytetrafluoroethylene / Q000009:adverse effects*; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D011859:Radiography
chemical_list: D000900:Anti-Bacterial Agents; D011138:Polytetrafluoroethylene