Determination of lidocaine in pharmaceutical preparations using thin-layer chromatographic densitometry.
A thin-layer chromatographic (TLC)-UV-densitometric method has been developed for the analysis of lidocaine in ointments, suppositories and gels. The method is quantitative, rapid and able to separate lidocaine from other components in the pharmaceutical dosage forms investigated without preliminary extraction. The method gave precise and reproducible results.
Zivanović
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L
Institute of Pharmaceutical Chemistry, Faculty of Pharmacy, Dr. Subotića 8, 11 000 Belgrade, Yugoslavia.
Zivanov-Stakić
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D
Radulović
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D