Cerebellum vasculopathy and normal tension glaucoma in systemic lupus erythematosus: report of a case and review of the literature.
Cerebellar vasculopathy is an uncommon but clinically important neuropsychiatric syndrome of systemic lupus erythematosus (NP-SLE) for its ominous outcome and need for prompt interventions. We described a young Chinese lady with systemic lupus erythematosus and normal tension glaucoma, who had sudden headache, nausea and vomiting coupled with rapid neurological deterioration leading to comatose status. Diagnosis of lupus cerebellar vasculopathy was made and intense immunosuppressive therapy consisting of prednisolone and cyclophosphamide was commenced. Clinical condition was salvaged with marked improvement of both sensorium and general well-being.
Chan
Alice Y K
AY
Department of Health, Social Hygiene Service, Hong Kong, China.
Li
Edmund K
EK
Wong
Grace L H
GL
Liu
David T L
DT
D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005901:Glaucoma / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000523:psychology; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
D003520:Cyclophosphamide; D011239:Prednisolone