title: Some new urinary metabolites of famprofazone and morazone in man.
abstract: The human urinary metabolism of two pyrazolone derivatives, morazone and famprofazone, has been investigated. After administration of morazone, the metabolites p-hydroxymorazone and phenazone-4-carboxylic acid were excreted in addition to the known metabolite, phenmetrazine, and unchanged morazone. Metabolism of famprofazone led to the formation of methamphetamine; the pyrazolone moiety was excreted as 3-hydroxymethyl-propyphenazone.
authors.affiliation: Pharmazeutisches Institut der Universität Bonn, Kreuzbergweg 26, D 5300 Bonn 1, Federal Republic of Germany.
authors.forename: M
authors.initials: M
authors.lastname: Neugebauer