In99, an In100-related integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal.
In99, a possible ancestor of In100, is a class 1 integron associated with carbenicillinase (blaPSE) and aminoglycoside resistance genes [aac(6')-Ib and aadA2]. In99 was present in 8 of 81 clinical isolates of Pseudomonas aeruginosa from unrelated patients collected in different years. The strains fell into two clonal groups and exhibited resistance to beta-lactams and aminoglycosides.
Caetano
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Departamento de Biologia, Universidade de Aveiro, Portugal.
Ferreira
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Mondego
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Correia
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Mendo
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D024881:Drug Resistance, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D032023:Integrons; D010405:Penicillinase / Q000235:genetics; D011174:Portugal; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics*
D010405:Penicillinase