title: Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery.
abstract: CONCLUSIONS
  Sinonasal malignancies without far lateral extension, intracranial invasion or orbital infiltration can be safely excised and reconstructed endoscopically with a satisfactory outcome.
  
  
  OBJECTIVE
  To evaluate the safety and efficacy of strictly endoscopic resection of malignant sinonasal neoplasms.
  
  
  METHODS
  Seven patients with sinonasal malignancies had received a minimally invasive endoscopic resection. Among them, two cases invaded the skull base. All patients were operated with curative intent.
  
  
  RESULTS
  All the tumors were removed successfully by strictly endoscopic surgery. Two patients who had invasion of the skull base (28.6%) accepted postoperative radiotherapy. No complications associated with the operation occurred. The patients were followed up for 15-57 months (average 36.4 months). No local recurrence was noted in this series to date. The disease-free survival rate was 100% at a mean follow-up duration of 36.4 months.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua and Chang Jung Christian University, Tainan, Taiwan. 53780@cch.org.tw
authors.forename: Mu-Kuan
authors.initials: MK
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology / Q000601:surgery; D018572:Disease-Free Survival; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009361:Neoplasm Invasiveness; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000601:surgery*; D012509:Sarcoma / Q000473:pathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*