Micelle-enhanced dissociation of a Ru cation /DNA complex.
Anionic surfactant monomers have a large catalytic effect on the dissociation rate constant of a Ru2(4+)-DNA complex, an effect further enhanced upon exceeding the critical micelle concentration. Electrostatic estimates are made of this effect, the effect of salt and temperature on the binding constant, and of the binding constant itself. The effects are compared with the experiment, and the calculated salt effect on the binding constant is compared with condensation theory. The results indicate that the catalytic effect is primarily nonelectrostatic (hydrophobic) in nature.
Marcus
R A
RA
Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, California 91125, USA. Ram@caltech.edu
D002412:Cations; D004247:DNA / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D007700:Kinetics; D008823:Micelles; D012428:Ruthenium / Q000737:chemistry*; D012492:Salts / Q000494:pharmacology; D055672:Static Electricity; D013501:Surface-Active Agents; D013696:Temperature
D002412:Cations; D008823:Micelles; D012492:Salts; D013501:Surface-Active Agents; D012428:Ruthenium; D004247:DNA