title: Multilobular tumor of the mandible in a Pekingese dog.
abstract: Multilobular tumor of bone detected in a 2.5-year-old male Pekingese dog is reported. Grossly, the neoplasm consisted of multiple, variably sized, gritty, grayish-white to yellow nodules separated by thick collagenous septa. Histologically, these nodules contained multiple lobules of irregularly shaped and sized islands of well-differentiated osteoid and cartilage, separated by anastomosing fibrovascular septa. Chondrocytes and osteocytes were observed in the lacunae and in more osseous islands in the lobule, respectively. These lobules were surrounded by mesenchymal spindle cells. Mitotic figures were not evident. The neoplastic pattern was consistent with that of a multilobular bone tumor. Diagnosis was based on gross and light microscopic findings. The cause of this neoplasm was not determined.
authors.affiliation: Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.
authors.forename: Bidur
authors.initials: B
authors.lastname: Pakhrin
authors.forename: Il Hong
authors.initials: IH
authors.lastname: Bae
authors.forename: Hyang
authors.initials: H
authors.lastname: Jee
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Kang
authors.forename: Dae Yong
authors.initials: DY
authors.lastname: Kim
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D006651:Histocytochemistry / Q000662:veterinary; D008297:Male; D008334:Mandible / Q000473:pathology* / Q000601:surgery; D012516:Osteosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*