title: Living donor right liver lobes: preoperative CT volumetric measurement for calculation of intraoperative weight and volume.
abstract: OBJECTIVE
  To prospectively develop equations for the calculation of expected intraoperative weight and volume of a living donor's right liver lobe by using preoperative computed tomography (CT) for volumetric measurement.
  
  
  METHODS
  After medical ethics committee and state medical board approval, informed consent was obtained from eight female and eight male living donors (age range, 18-63 years) for participation in preoperative CT volumetric measurement of the right liver lobes by using the summation-of-area method. Intraoperatively, the graft was weighed, and the volume of the graft was determined by means of water displacement. Distributions of pre- and intraoperative data were depicted as Tukey box-and-whisker diagrams. Then, linear regressions were calculated, and the results were depicted as scatterplots. On the basis of intraoperative data, physical density of the parenchyma was calculated by dividing weight by volume of the graft.
  
  
  RESULTS
  Preoperative measurement of grafts resulted in a mean volume of 929 mL +/- 176 (standard deviation); intraoperative mean weight and volume of the grafts were 774 g +/- 138 and 697 mL +/- 139, respectively. All corresponding pre- and intraoperative data correlated significantly (P < .001) with each other. Intraoperatively expected volume (V(intraop)) in millilliters and weight (W(intraop)) in grams can be calculated with the equations V(intra)(op) = (0.656 . V(preop)) + 87.629 mL and W(intra)(op) = (0.678 g/mL . V(preop)) + 143.704 g, respectively, where preoperative volume is V(preop) in milliliters. Physical density of transplanted liver lobes was 1.1172 g/mL +/- 0.1015.
  
  
  CONCLUSIONS
  By using two equations developed from the data obtained in this study, expected intraoperative weight and volume can properly be determined from CT volumetric measurements.
authors.affiliation: Departments of Radiology and General, Visceral, and Transplant Surgery Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany. lemke@charite.de
authors.forename: Arne-Jörn
authors.initials: AJ
authors.lastname: Lemke
authors.forename: Martin Julius
authors.initials: MJ
authors.lastname: Brinkmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Schott
authors.forename: Stefan Markus
authors.initials: SM
authors.lastname: Niehues
authors.forename: Utz
authors.initials: U
authors.lastname: Settmacher
authors.forename: Peter
authors.initials: P
authors.lastname: Neuhaus
authors.forename: Roland
authors.initials: R
authors.lastname: Felix
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D016031:Liver Transplantation / Q000379:methods; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011300:Preoperative Care; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed