Haterumadysins A-D, sesquiterpenes from the Okinawan marine sponge Dysidea chlorea.
Haterumadysins A-D (1-4) and two known compounds, spirodysin (5) and dehydroherbadysinolide (6), were isolated from the sponge Dysidea chlorea. Their structures were successfully determined by detailed spectroscopic analysis. Compounds 1-5 all showed the ability to inhibit the division of fertilized sea urchin eggs.
Ueda
Katsuhiro
K
Department of Chemistry, Biology and Marine Sciences, University of the Ryukyus, Nishiharacho, Okinawa 903-0213, Japan. kueda@sci.u-ryukyu.ac.jp
Kadekaru
Takashi
T
Siwu
Eric R O
ER
Kita
Masaki
M
Uemura
Daisuke
D
D000818:Animals; D047088:Dysidea / Q000737:chemistry*; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012617:Sea Urchins / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015053:Zygote / Q000187:drug effects
D012717:Sesquiterpenes