title: Porokeratosis of Mibelli induced by topical corticosteroid.
abstract: BACKGROUND
  [corrected] Prorokeratosis of Mibelli is a chronic disorder characterised by slightly atrophic plaques surrounded by keratotic border.
  
  
  RESULTS
  A 45-year-old with clobetazole propionate ointment for psoriasis over 15 years developed characteristic lesions of porokeratosis Mibelli on the elbows. Histopathological examination revealed the cornoid lamellae located on the edges of the specimen and psoriasiform acanthosis and a spongiotic pustule formation in the center of the specimen; thus, it was suggested as 'psoriasis encircled by porokeratosis'.
  
  
  CONCLUSIONS
  Development of porokeratosis may be explained by the local immunosuppressive effect of the prolonged application of the topical steroid.
authors.affiliation: Department of Dermatology, Ege University Medical Faculty, Bornova-Izmir, Turkey.
authors.forename: Figen
authors.initials: F
authors.lastname: Yazkan
authors.forename: Bengu Gerceker
authors.initials: BG
authors.lastname: Turk
authors.forename: Tugrul
authors.initials: T
authors.lastname: Dereli
authors.forename: Ali Can
authors.initials: AC
authors.lastname: Kazandi
mesh_terms: D000052:Acanthosis Nigricans / Q000473:pathology; D017115:Catheter Ablation; D002990:Clobetasol / Q000009:adverse effects*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D017499:Porokeratosis / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D011565:Psoriasis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D002990:Clobetasol