The acute effects of different sources of dietary calcium on postprandial energy metabolism.
Dairy Ca intake has been shown to be superior to elemental Ca in increasing the loss of body fat during energy restriction. We questioned whether the mechanisms involved an increase in postprandial energy expenditure, fat oxidation and/or a greater lipolysis. The acute effects of different sources of Ca were examined in eight subjects, aged 47-66 years and BMI 27.6-36.1 kg/m2, in a three-way cross-over study. Subjects were randomly provided breakfast meals either low in dairy Ca and vitamin D (LD; control), high in non-dairy Ca (calcium citrate) but low in vitamin D (HC) or high in dairy Ca and vitamin D (HD). Diet-induced thermogenesis, fat oxidation rates (FOR), carbohydrate oxidation rates (COR), insulin, glucose, NEFA and glycerol were measured hourly over a 6 h postprandial period. Postprandial data were calculated as a change (Delta) from the fasting value. Results showed that DeltaNEFA was significantly different between meals (LD -1.50 (sem 0.26), HC -1.22 (sem 0.32), HD -0.94 (sem 0.27) mmol/l x 6 h; P = 0.035), with a lesser suppression following both high-Ca meals. DeltaFOR was significantly higher following the two high-Ca meals (LD -6.5 (sem 2.2), HC 2.93 (sem 2.34), HD 3.3 (sem 2.5) g x 6 h; P = 0.005), while reciprocally DeltaCOR was significantly lower. DeltaGlycerol was less suppressed following the high-Ca meals but statistical significance was not achieved. No differences in diet-induced thermogenesis, insulin or glucose were observed. Regardless of source, Ca intake acutely stimulated postprandial fat oxidation; and there was a lesser suppression of NEFA following these meals.
Cummings
Nicola K
NK
Program of Nutrition, Dietetics and Food Science, School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia.
James
Anthony P
AP
Soares
Mario J
MJ
D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D019355:Calcium Citrate / Q000008:administration & dosage; D002136:Calcium, Dietary / Q000008:administration & dosage*; D050260:Carbohydrate Metabolism / Q000502:physiology; D018592:Cross-Over Studies; D003611:Dairy Products; D004734:Energy Metabolism / Q000502:physiology*; D005223:Fats / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005990:Glycerol / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D010084:Oxidation-Reduction; D019518:Postprandial Period; D016037:Single-Blind Method; D022722:Thermogenesis / Q000502:physiology; D014807:Vitamin D / Q000008:administration & dosage*
D001786:Blood Glucose; D002136:Calcium, Dietary; D005223:Fats; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D014807:Vitamin D; D019355:Calcium Citrate; D005990:Glycerol