title: A drop tower for controlled impact testing of biological tissues.
abstract: Impact damage, in particular to tissues such as articular cartilage, is a recognised source of morbidity. To understand better the clinical outcomes, it is important to know the mechanics of the damage sustained and the biological response of cells to rapidly applied forces and subsequent tissue disruption. An instrumented drop tower has been designed to enable controlled impact loads to be applied to small samples of biological materials. Impact severity can be controlled by using impactors of different masses and various drop heights. Force and deceleration at impact are recorded at 50,000 samples s(-1) by a force transducer under the sample and an accelerometer on the impactor. Repeatability was tested on rubber washers and coefficients of variation were found to be better than 8% for dynamic stiffness, 3.4% for stress and 4.3% for strain. Initial tests on isolated biopsies of articular cartilage showed that at an initial strain rate of 916 s(-1), the peak dynamic modulus of human femoral head cartilage was 59 MPa, and for a bovine biopsy the initial strain rate and corresponding peak dynamic modulus were 3380 s(-1) and 130 MPa, respectively. The equipment described is capable of applying an impact load to small biopsies of tissue with a defined energy and velocity and measuring deformation and load at high rates of loading.
authors.affiliation: Department of Orthopaedic Surgery, University of Aberdeen, IMS Building, Foresterhill, Aberdeen, UK.
authors.forename: Leanne V
authors.initials: LV
authors.lastname: Burgin
authors.forename: Richard M
authors.initials: RM
authors.lastname: Aspden
mesh_terms: D000369:Aged, 80 and over; D000818:Animals; D001696:Biomechanical Phenomena / Q000295:instrumentation; D002358:Cartilage, Articular / Q000473:pathology / Q000503:physiopathology*; D002417:Cattle; D005264:Femoral Fractures / Q000473:pathology; D006801:Humans; D013314:Stress, Mechanical; D013718:Tensile Strength