Medical therapy for refractory pediatric Crohn's disease.
Crohn's disease is a common indication for referral to pediatric gastroenterology. While most patients with Crohn's disease respond to standard induction therapy, steroid-refractory or steroid-dependent disease is a frequently encountered problem. This review discusses the data existing in both the adult and pediatric literature for medical therapy of refractory pediatric Crohn's disease.
Faubion
William A
WA
Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA. Faubion.william@mayo.edu
Bousvaros
Athos
A
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D065095:Calcineurin Inhibitors; D002648:Child; D003424:Crohn Disease / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D018579:Patient Selection; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D000893:Anti-Inflammatory Agents; D065095:Calcineurin Inhibitors; D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha