title: Effects of oral vaccination against Lawsonia intracellularis on growing-finishing pig's performance in a pig production unit with endemic porcine proliferative enteropathy (PPE).
abstract: The aim of the present study was to evaluate the effect of oral vaccination against Lawsonia intracellularis (LI) on growing-finishing pig's performance. In a large Hungarian growing-finishing pig production unit, pigs with positive LI status were randomly divided into 2 groups and treated as follows: Group one: growing pigs (n = 4112) were LI vaccinated with an avirulent oral live vaccine (Enterisol Ileitis Boehringer Ingelheim Vetmedica, Inc., St. Joseph, USA). Group two: growing pigs (n = 4188 pigs) have not received LI vaccination. Culling and mortality rates, reasons for culling or mortality, and average daily weight gain were evaluated. Porcine proliferative enteropathy (PPE) caused culling and mortality rates were lower (0.2 % vs. 14.9 %, P < 0.001), and vaccinated pigs had lower none-PPE caused culling and mortality rates compared with the non-vaccinated ones (1.4 vs. 2.6 %, P > 0.05). While systemic infections and social stress or cannibalism related culling or mortality were significantly (P < 0.05) lower in vaccinated than in non-vaccinated pigs, reasons for culling or mortality due to non-LI caused diseases were non-significantly different between the vaccinated and non-vaccinated pigs. Average daily weight gain was higher (P < 0.05) in the LI vaccinated group of animals compared with the non-vaccinated ones (780 +/- 45 g vs. 660 +/- 71 g). The present results indicate that that LI vaccination does not only prevent PPE, but might result in more resistance and tolerance against other infectious and management caused losses.
authors.affiliation: Bilkei Consulting, Dübendorf, Switzerland.
authors.forename: P K
authors.initials: PK
authors.lastname: Almond
authors.forename: G
authors.initials: G
authors.lastname: Bilkei
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001428:Bacterial Vaccines; D045824:Desulfovibrionaceae Infections / Q000401:mortality / Q000517:prevention & control / Q000662:veterinary*; D005260:Female; D020639:Lawsonia Bacteria / Q000276:immunology*; D008297:Male; D011897:Random Allocation; D013552:Swine; D013553:Swine Diseases / Q000401:mortality / Q000517:prevention & control*; D014611:Vaccination / Q000379:methods / Q000662:veterinary; D014613:Vaccines, Attenuated; D015430:Weight Gain
chemical_list: D001428:Bacterial Vaccines; D014613:Vaccines, Attenuated