Direct, one-step synthesis of condensed heterocycles: a palladium-catalyzed coupling approach.
[reaction: see text] A palladium-catalyzed one-step synthesis of fused aromatic heterocycles from bifunctional bromoenoates or bromoalkyl indoles and iodoarenes is reported. This method provides an efficient route to a wide variety of substituted polycyclic aromatic and heteroaromatic compounds from readily accessible starting materials.
Jafarpour
Farnaz
F
Davenport Chemical Research Laboratories, Chemistry Department, University of Toronto, Toronto, Ontario, Canada M5S 3H6.
Lautens
Mark
M