title: Evaluation of the antimicrobial activity of each component in Grossman's sealer.
abstract: The antimicrobial activity of Grossman's sealer and its components was evaluated on 13 different strains using the double layer well-diffusion method. Results revealed that Grossman's sealer presented antimicrobial activity against all the tested strains. Among the components of the cement, sodium tetraborate presented the greatest antimicrobial activity, both in type and diameter of the halo and ring of inhibition. Sealer powder, rosin, and eugenol presented similar activity, with no effect on P. aeruginosa and C. albicans. Among these, only eugenol had an effect on E. coli. Zinc oxide was only active against S. sobrinus and E. coli. Barium sulfate and bismuth subcarbonate did not show any antimicrobial effect.
authors.affiliation: Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto.
authors.forename: Ricardo Novak
authors.initials: RN
authors.lastname: Savioli
authors.forename: Jesus Djalma
authors.initials: JD
authors.lastname: Pecora
authors.forename: Henis
authors.initials: H
authors.lastname: Mian
authors.forename: Izabel Yoko
authors.initials: IY
authors.lastname: Ito
mesh_terms: D000891:Anti-Infective Agents, Local / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D003786:Dental Pulp Cavity / Q000382:microbiology*; D006801:Humans; D008422:Materials Testing; D012387:Root Canal Filling Materials / Q000737:chemistry / Q000494:pharmacology*; D012389:Root Canal Obturation; D018915:Root Canal Preparation / Q000379:methods; D015035:Zinc Oxide-Eugenol Cement / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000891:Anti-Infective Agents, Local; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; C045432:Grossman's sealer