title: A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses.
abstract: The interaction of ERalpha and ERbeta with ERE constitutes the initial step in the canonical nuclear E2 signaling in which E2-ERbeta is a weaker transactivator than E2-ERalpha. This perspective summarizes recent findings to discuss potential mechanisms that contribute to ER subtype-specific transcriptional responses.
authors.affiliation: Department of Biochemistry and Biophysics, University of Rochester Medical School, Rochester, NY, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Huang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Qiao
authors.forename: Robert A
authors.initials: RA
authors.lastname: Bambara
authors.forename: Russell
authors.initials: R
authors.lastname: Hilf
authors.forename: Mesut
authors.initials: M
authors.lastname: Muyan