title: Nano DCPA-whisker composites with high strength and Ca and PO(4) release.
abstract: The main challenges facing composite restorations are secondary caries and bulk fracture. The objective of this study was to develop nano DCPA (dicalcium phosphate anhydrous)-whisker composites with high strength and Ca and PO(4) ion release to combat caries. Flexural strength for the nano DCPA-whisker composites at a nano DCPA:whisker mass ratio of 1:2 ranged from (148 +/- 9) MPa to (167 +/- 23) MPa, significantly higher than the (103 +/- 32) MPa of an inlay/onlay commercial control composite without Ca-PO(4) release. The nano DCPA-whisker composite released PO(4) to a concentration of (1.95 +/- 0.13) mmol/L and Ca of (0.68 +/- 0.05) mmol/L. Compared with previous conventional Ca- and PO(4)-releasing composites, the nano DCPA-whisker composites had strengths two-fold higher, and released comparable or higher levels of Ca and PO(4). In conclusion, combining nano-DCPA with whiskers yielded novel composites that released high levels of Ca and PO(4) requisite for remineralization. These high-strength composites may provide a unique combination of stress-bearing and caries-inhibiting capabilities.
authors.affiliation: Building 224, Room A-153, Stop 8546, Paffenbarger Research Center, American Dental Association Foundation, Gaithersburg, MD 20899-8546, USA.hockin.xu@nist.gov
authors.forename: H H K
authors.initials: HH
authors.lastname: Xu
authors.forename: L
authors.initials: L
authors.lastname: Sun
authors.forename: M D
authors.initials: MD
authors.lastname: Weir
authors.forename: J M
authors.initials: JM
authors.lastname: Antonucci
authors.forename: S
authors.initials: S
authors.lastname: Takagi
authors.forename: L C
authors.initials: LC
authors.lastname: Chow
authors.forename: M
authors.initials: M
authors.lastname: Peltz
mesh_terms: D000704:Analysis of Variance; D002118:Calcium / Q000032:analysis; D002130:Calcium Phosphates / Q000737:chemistry; D017554:Carbon Compounds, Inorganic / Q000737:chemistry; D002327:Cariostatic Agents / Q000032:analysis; D003188:Composite Resins / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods; D003799:Dental Stress Analysis; D008422:Materials Testing; D008689:Methacrylates; D049329:Nanostructures; D010710:Phosphates / Q000032:analysis; D018583:Pliability; D017655:Silicon Compounds / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; D017554:Carbon Compounds, Inorganic; D002327:Cariostatic Agents; D003188:Composite Resins; D008689:Methacrylates; D010710:Phosphates; D017655:Silicon Compounds; C005044:hydroxyethyl methacrylate; C485829:calcium phosphate, dibasic, anhydrous; D002118:Calcium; C022088:silicon carbide