title: Chemoprevention of prostate cancer.
abstract: Prostate cancer is a common malignancy with multiple potential opportunities for cancer prevention. As the genetic basis of this malignancy is further understood, prevention strategies will be developed for individual patients based on specific risk factors and pathways of carcinogenesis. The PCPT has conclusively proven that prostate cancer prevention is possible. The results of the SELECT should be available within several years. An enormous challenge for the medical community will be the development of an efficient strategy to evaluate the substantial number of dietary, behavioral, and pharmacologic prevention opportunities. Ultimately, the goal of prostate can-cer prevention is to (1) identify men who are destined to develop clinically significant prostate cancer, and (2) provide individualized agents to prevent disease development.
authors.affiliation: University of Texas Health Science Center, San Antonio, TX 78229, USA.
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Brand
authors.forename: Edith D
authors.initials: ED
authors.lastname: Canby-Hagino
authors.forename: A
authors.initials: A
authors.lastname: Pratap Kumar
authors.forename: Rita
authors.initials: R
authors.lastname: Ghosh
authors.forename: Robin J
authors.initials: RJ
authors.lastname: Leach
authors.forename: Ian M
authors.initials: IM
authors.lastname: Thompson
mesh_terms: D016588:Anticarcinogenic Agents / Q000627:therapeutic use; D018890:Chemoprevention / Q000379:methods*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000517:prevention & control*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D016588:Anticarcinogenic Agents