[Expression of substance P in human laryngopharynx and gastrointestine in sudden erethistic death].
OBJECTIVE
To study the expression of substance P (SP) in human sudden erethistic death, and to seek objective morphological supports to diagnose sudden erethistic death for forensic medicine.


METHODS
The expression of SP was detected with immunohistochemical technique on 15 human laryngopharynx and gastrointestine of sudden erethistic death, and 20 sudden death of heart attack as control. The images of SP were analyzed by image analyzer, and the positive indexes (PI) were calculated.


RESULTS
SP expression in the experimental groups was significantly stronger than that in the control one (P < 0.001).


CONCLUSIONS
SP expression can offer an objective morphological reference support for forensic diagnosing sudden erethistic death.
Sun
Hong-Wei
HW
School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China. shwei2002nm@yahoo.com.cn
Gao
Cai-Rong
CR
Ren
Gang-Mu
GM
Sun
Jun-Hong
JH
Lu
Jian
J
Wang
Ying-Yuan
YY
D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000378:metabolism* / Q000473:pathology; D001344:Autopsy; D002648:Child; D003645:Death, Sudden; D016757:Death, Sudden, Cardiac / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000378:metabolism; D010614:Pharynx / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*; D055815:Young Adult
D013373:Substance P