Differences in resistance to Salmonella enterica serovar Gallinarum infection among indigenous local chicken ecotypes in Tanzania.
A study was conducted to evaluate the disease resistance potential in 105 chickens of six indigenous local chicken ecotypes in Tanzania by orally challenging 1-week-old chicks with 2.5 x 10(8) colony-forming units of virulent S. Gallinarum. For 14 days post infection, clinical signs, necropsy findings, antibody titres, packed cell volume, leukocyte population count, and viable bacterial cell counts in the liver and spleen were recorded. Clinical signs were recorded daily but other parameters were recorded on the day of infection, then on days 3, 6, 10 and 14 after infection. Clinical signs of fowl typhoid were evident in chickens from day 3 post infection and disappeared by day 9 post infection. Pathological lesions on sacrificed birds included enlargement of the liver and spleen with foci of necrosis on the liver, spleen and myocardium. The mean viable bacterial cell counts in the liver and spleen varied between ecotypes, although the differences were not statistically significant. There were significant differences in the leukocyte population in the peripheral blood, with one ecotype (Morogoro-medium) showing a consistent and significantly higher heterophil count compared with other ecotypes. It was concluded that there is a selectable resistance potential to S. Gallinarum among the local chicken ecotypes in Tanzania that may be attributable to non-specific host immune responses. Further studies are suggested.
Msoffe
P L M
PL
Department of Veterinary Medicine and Public Health, P.O. Box 3021, Morogoro, Tanzania. makeengamsoffe@yahoo.co.uk
Minga
U M
UM
Mtambo
M M A
MM
Gwakisa
P S
PS
Olsen
J E
JE
D000818:Animals; D002645:Chickens / Q000235:genetics* / Q000276:immunology; D020022:Genetic Predisposition to Disease; D011201:Poultry Diseases / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology / Q000382:microbiology; D012481:Salmonella Infections, Animal / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology / Q000382:microbiology; D019779:Salmonella enterica; D013636:Tanzania / Q000453:epidemiology; D013997:Time Factors