Direct observation of surface-mediated thioacetyl deprotection: covalent tethering of a thiol-terminated porphyrin to the Ag(100) surface.
Covalent tethering of macromolecules such as porphyrins to metal surfaces underpins bottom-up fabrication of systems intended for a variety of applications. Thiol linkages are especially useful but often need protection during macromolecule synthesis. By means of scanning tunneling microscopy, we directly observe the spontaneous deprotection of an acetyl-protected thioporphyrin upon contact with a silver surface, without the intervention of any solution-mediated chemistry.
Vaughan
Owain P H
OP
Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.
Turner
Mark
M
Williams
Federico J
FJ
Hille
Andreas
A
Sanders
Jeremy K M
JK
Lambert
Richard M
RM