title: [General reproductive toxicity assessment in mice exposed to low-level ozone].
abstract: OBJECTIVE
  To explore the general reproductive toxicity in mice exposed to low-level ozone.
  
  
  METHODS
  Low-level (0.09 approximately 0.18 mg/m3) ozone was created by 15 W ultraviolet light. The mice in 3 experimental groups and a control group were fed in low-level ozone environment or normal environment, respectively, and then the mating experiment was conducted. The pregnancy rate and the weight variations of the female mice were observed. The weight of the live fetuses was observed, and the appearance, bone and internal organs were checked for malformation.
  
  
  RESULTS
  There were no significant differences in any indexes between the experimental groups and the control group.
  
  
  CONCLUSIONS
  Low-level ozone created by 15 W ultraviolet light may not have reproductive toxicity in mice.
authors.affiliation: Department of Laboratory Animal, Central South University, Changsha, China.
authors.forename: Zhi-jun
authors.initials: ZJ
authors.lastname: Zhou
authors.forename: Zheng-shi
authors.initials: ZS
authors.lastname: Zhou
authors.forename: Bai-zheng
authors.initials: BZ
authors.lastname: Tang
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D005298:Fertility / Q000187:drug effects*; D019570:Inhalation Exposure / Q000009:adverse effects*; D008297:Male; D051379:Mice; D019055:No-Observed-Adverse-Effect Level; D010126:Ozone / Q000633:toxicity*; D011897:Random Allocation; D012098:Reproduction / Q000187:drug effects*; D014466:Ultraviolet Rays
chemical_list: D010126:Ozone