Core/shell quantum-dot-photosensitized nano-TiO2 films: fabrication and application to the damage of cells and DNA.
Through the use of monodisperse core/shell quantum dots (QDs) as photosensitizers for the first time, a novel strategy for the fabrication of QD-photosensitized nano-TiO2 films was demonstrated. Core/shell QDs were self-assembled on nano-TiO2 films through carboxyls as anchoring groups to metal oxides. Atomic force microscopy and some other experiments showed the fabrication strategy is successful. Reactive oxygen species detection experiments indicated that such films have photosensitization ability. The results of bactericidal and DNA damage experiments demonstrate that such films have excellent photoactivity.
Lu
Zhe-Xue
ZX
College of Chemistry and Molecular Sciences and State Key Laboratory of Virology, Wuhan University, Wuhan 430072, People's Republic of China.
Zhang
Zhi-Ling
ZL
Zhang
Ming-Xi
MX
Xie
Hai-Yan
HY
Tian
Zhi-Quan
ZQ
Chen
Ping
P
Huang
Hua
H
Pang
Dai-Wen
DW
D004247:DNA / Q000737:chemistry* / Q000187:drug effects; D004249:DNA Damage; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000254:growth & development; D008567:Membranes, Artificial; D049329:Nanostructures / Q000737:chemistry*; D010777:Photochemistry; D045663:Quantum Dots; D017382:Reactive Oxygen Species / Q000032:analysis / Q000737:chemistry; D012680:Sensitivity and Specificity; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology
D008567:Membranes, Artificial; D017382:Reactive Oxygen Species; C009495:titanium dioxide; D004247:DNA; D014025:Titanium