The interaction between pathogens and the host coagulation system.
There is mounting evidence that the hemostatic system is critical in host responses to bacterial infection. Invasive bacteria have evolved virulence strategies to interact with host hemostatic factors such as plasminogen and fibrinogen for infection. Furthermore, genetic variations in host hemostatic factors also influence host response to bacterial infection.
Sun
Hongmin
H
Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. hongmin@umich.edu
D000818:Animals; D001424:Bacterial Infections / Q000503:physiopathology*; D001777:Blood Coagulation / Q000235:genetics / Q000502:physiology*; D017848:Blood-Borne Pathogens; D005340:Fibrinogen / Q000502:physiology; D014644:Genetic Variation; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D010958:Plasminogen / Q000502:physiology; D013927:Thrombosis / Q000503:physiopathology
D005340:Fibrinogen; D010958:Plasminogen