Chemoprevention of prostate cancer.
Prostate cancer is a common malignancy with multiple potential opportunities for cancer prevention. As the genetic basis of this malignancy is further understood, prevention strategies will be developed for individual patients based on specific risk factors and pathways of carcinogenesis. The PCPT has conclusively proven that prostate cancer prevention is possible. The results of the SELECT should be available within several years. An enormous challenge for the medical community will be the development of an efficient strategy to evaluate the substantial number of dietary, behavioral, and pharmacologic prevention opportunities. Ultimately, the goal of prostate can-cer prevention is to (1) identify men who are destined to develop clinically significant prostate cancer, and (2) provide individualized agents to prevent disease development.
Brand
Timothy C
TC
University of Texas Health Science Center, San Antonio, TX 78229, USA.
Canby-Hagino
Edith D
ED
Pratap Kumar
A
A
Ghosh
Rita
R
Leach
Robin J
RJ
Thompson
Ian M
IM
D016588:Anticarcinogenic Agents / Q000627:therapeutic use; D018890:Chemoprevention / Q000379:methods*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000517:prevention & control*; D018570:Risk Assessment; D016896:Treatment Outcome
D016588:Anticarcinogenic Agents