title: Gemcitabine and radiotherapy in the treatment of uterine cervical cancer patients at Phramongkutklao Hospital.
abstract: OBJECTIVE
  To determine response, complication and survival of uterine cervical cancer patients treated with concurrent gemcitabine radiotherapy.
  
  
  METHODS
  A retrospective review of medical records of 41 patients with uterine cervical cancer patients, stage IIB and above treated with concurrent gemcitabine radiotherapy from August 2000 to August 2003.
  
  
  RESULTS
  At 6 and 12 months of follow up, the complete response rate was 75.6% and 65.9%. The cumulative probability of survival at 6 and 12 months after treatment was 0.93 and 0.85. The main complications were mild hematologic and nonhematologic toxicities.
  
  
  CONCLUSIONS
  Concurrent gemcitabine radiotherapy provided a satisfactory response in patients with uterine cervical cancer with mild toxicity. Long term follow up data is necessary to determine the recurrent rate of this regimen.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Phramongkutklao Hospital, Bangkok, Thailand. phanidajw@yahoo.com
authors.forename: Phanida
authors.initials: P
authors.lastname: Jarruwale
authors.forename: Yawana
authors.initials: Y
authors.lastname: Tanapat
authors.forename: Pote
authors.initials: P
authors.lastname: Aimpun
mesh_terms: D000328:Adult; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013785:Thailand; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy*; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine