Drug-induced systemic lupus erythematosus after 7 years of treatment with carbamazepine.
Aim of this work is to describe a late-onset of carbamazepine-induced systemic lupus erythematosus (SLE) in a 38-year-old female patient who had been treated with daily carbamazepine (CBZ) for 7 years because of a bipolar I disorder. When CBZ was discontinued, symptoms rapidly improved and antinuclear antibodies (ANA) disappeared. So far, only few cases have been reported of CBZ-induced SLE within months after the beginning of treatment. This is the second (first italian) case report in literature about CBZ-induced SLE with serological confirmation after years of treatment without previous side effects.
Pelizza
Lorenzo
L
Psychiatric Operative Unit n.25 of Casalmaggiore (Cremona), "Oglio Po" General Hospital, Italy. anolino@yahoo.it
De Luca
Pasquale
P
La Pesa
Maurizio
M
Minervino
Antonino
A
D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects*; D002220:Carbamazepine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D013997:Time Factors
D018692:Antimanic Agents; D002220:Carbamazepine