title: Dengue infection: neurological manifestations and cerebrospinal fluid (CSF) analysis.
abstract: Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.
authors.affiliation: Neurology Service, HUAP/UFF (Hospital Universitário Antônio Pedro/Universidade Federal Fluminense), Niterói, RJ, Brazil. crist_nsoares@yahoo.com.br
authors.forename: C N
authors.initials: CN
authors.lastname: Soares
authors.forename: L C
authors.initials: LC
authors.lastname: Faria
authors.forename: J M
authors.initials: JM
authors.lastname: Peralta
authors.forename: M R G
authors.initials: MR
authors.lastname: de Freitas
authors.forename: M
authors.initials: M
authors.lastname: Puccioni-Sohler
mesh_terms: D000328:Adult; D000368:Aged; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis / Q000276:immunology*; D002648:Child; D003715:Dengue / Q000150:complications*; D003716:Dengue Virus / Q000276:immunology*; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D005260:Female; D020275:Guillain-Barre Syndrome / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009187:Myelitis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D011237:Predictive Value of Tests; D012703:Serotyping; D013116:Spinal Cord / Q000473:pathology / Q000503:physiopathology / Q000821:virology
chemical_list: D002556:Cerebrospinal Fluid Proteins; D007075:Immunoglobulin M