Levodopa can worsen tremor associated with dystonia.
A patient with tremor associated with spasmodic dysphonia developed a marked exacerbation of her upper limb tremor whilst on co-careldopa (Sinemet CR) that improved when the drug was withdrawn.
Hensman
Davina J
DJ
St. George's, University of London, United Kingdom.
Bain
Peter G
PG
D000368:Aged; D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002230:Carbidopa / Q000009:adverse effects* / Q000627:therapeutic use; D003951:Diagnostic Errors; D004338:Drug Combinations; D004421:Dystonia / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects* / Q000627:therapeutic use; D009460:Neurologic Examination; D020734:Parkinsonian Disorders / Q000175:diagnosis / Q000188:drug therapy*; D011597:Psychomotor Performance / Q000187:drug effects; D014202:Tremor / Q000139:chemically induced* / Q000175:diagnosis
D000978:Antiparkinson Agents; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa