title: Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials.
abstract: We present a simple method of fabricating highly potent dual action antibacterial composites consisting of a cationic polymer matrix and embedded silver bromide nanoparticles. A simple and novel technique of on-site precipitation of AgBr was used to synthesize the polymer/nanoparticle composites. The synthesized composites have potent antibacterial activity toward both gram-positive and gram-negative bacteria. The materials form good coatings on surfaces and kill both airborne and waterborne bacteria. Surfaces coated with these composites resist biofilm formation. These composites are different from other silver-containing antibacterial materials both in the ease of synthesis and in the use of a silver salt nanoparticle instead of elemental silver or complex silver compounds. We also demonstrate the ability to tune the release of biocidal Ag(+) ions from these composites by controlling the size of the embedded AgBr nanoparticles. These composites are potentially useful as antimicrobial coatings in a wide variety of biomedical and general use applications.
authors.affiliation: Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
authors.forename: Varun
authors.initials: V
authors.lastname: Sambhy
authors.forename: Megan M
authors.initials: MM
authors.lastname: MacBride
authors.forename: Blake R
authors.initials: BR
authors.lastname: Peterson
authors.forename: Ayusman
authors.initials: A
authors.lastname: Sen
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001965:Bromides / Q000737:chemistry*; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D018030:Silver Compounds / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D001965:Bromides; D011108:Polymers; D018030:Silver Compounds; C047751:silver bromide