The identification and stereochemical study of tetracycline antibiotics by 1H nuclear magnetic resonance spectroscopy.
The 1H NMR spectra of seven tetracycline antibiotics of clinical importance are reported and assigned as solutes in DMSO-d6 and other solvents. The data are analysed in terms of analytical utility and the provision of evidence of solute stereochemistry.
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School of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
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