title: Auxin signaling.
abstract: Auxin regulates a host of plant developmental and physiological processes, including embryogenesis, vascular differentiation, organogenesis, tropic growth, and root and shoot architecture. Genetic and biochemical studies carried out over the past decade have revealed that much of this regulation involves the SCF(TIR1/AFB)-mediated proteolysis of the Aux/IAA family of transcriptional regulators. With the recent finding that the TRANSPORT INHIBITOR RESPONSE1 (TIR1)/AUXIN SIGNALING F-BOX (AFB) proteins also function as auxin receptors, a potentially complete, and surprisingly simple, signaling pathway from perception to transcriptional response is now before us. However, understanding how this seemingly simple pathway controls the myriad of specific auxin responses remains a daunting challenge, and compelling evidence exists for SCF(TIR1/AFB)-independent auxin signaling pathways.
authors.affiliation: Department of Plant Biology, University of Minnesota - Twin Cities, St. Paul, Minnesota 55108, USA.
authors.forename: Marcel
authors.initials: M
authors.lastname: Quint
authors.forename: William M
authors.initials: WM
authors.lastname: Gray
mesh_terms: D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000378:metabolism*; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D044843:SKP Cullin F-Box Protein Ligases / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D007210:Indoleacetic Acids; D010937:Plant Growth Regulators; D010940:Plant Proteins; D011956:Receptors, Cell Surface; C046131:auxin receptor, plant; D044843:SKP Cullin F-Box Protein Ligases