The evidence for carotid stenting versus carotid endarterectomy in symptomatic patients.
Large randomized trials have demonstrated the value of surgical intervention for symptomatic carotid artery disease in stroke prevention. More recently trials have also demonstrated benefit in asymptomatic patients. However, the benefit of surgery comes with significant burden in terms of a risk of both stroke at the time of procedure and other complications. Less invasive endovascular techniques might reduce this complication rate whilst proving as effective as surgery. At the time of writing conclusive evidence is still being sought but a Cochrane meta-analysis has indicated that with the current knowledge based on randomised trials the neuro-embolic complication rate at 30 days is equivalent between the two therapies. Endovascular techniques have fewer non-neuroembolic complications.
Gaines
P A
PA
Sheffield Vascular Institute, Northern General Hospital, Sheffield, UK. P.A.Gaines@Sheffield.ac.uk
D001807:Blood Vessel Prosthesis / Q000706:statistics & numerical data*; D016893:Carotid Stenosis / Q000453:epidemiology* / Q000601:surgery*; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D016894:Endarterectomy, Carotid / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine / Q000706:statistics & numerical data; D006801:Humans; D010818:Practice Patterns, Physicians'; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D015607:Stents / Q000706:statistics & numerical data*; D016896:Treatment Outcome