title: Spongian diterpenes from Australian Nudibranchs: an anatomically guided chemical study of Glossodoris atromarginata.
abstract: An Australian population of the nudibranch mollusk Glossodoris atromarginata has been found to contain furanoditerpenes of the spongian series. Spongia-13(16),14-dien-3-one (1) and 3alpha-acetoxy-19-hydroxyspongia-13(16),14-dien-2-one [corrected] (2) were isolated for the first time from a natural source, along with a series of known diterpenes (3-7). Anatomical dissection of the animals revealed the relative distribution and chemical variation of secondary metabolites. Structural studies have provided a basis for chemical comparisons between populations from different geographic locations.
authors.affiliation: School of Molecular and Microbial Sciences, The University of Queensland, Brisbane QLD 4072, Australia.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Somerville
authors.forename: Ernesto
authors.initials: E
authors.lastname: Mollo
authors.forename: Guido
authors.initials: G
authors.lastname: Cimino
authors.forename: Wimolpun
authors.initials: W
authors.lastname: Rungprom
authors.forename: Mary J
authors.initials: MJ
authors.lastname: Garson
mesh_terms: D000818:Animals; D001315:Australia; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*
chemical_list: C513468:3beta-acetoxy-19-hydroxyspongia-13(16),14-dien-2-one; D004224:Diterpenes; C513467:spongia-13(16),14-dien-3-one