title: [Avascular necrosis of the bone in patients with HIV infection: an emergent problem].
abstract: Since avascular necrosis of the bone was first described in a HIV infected patient in 1990, its incidence has increased, especially in recent years. The hip is most commonly involved and often bilaterally. We report a series of 5 cases of avascular necrosis of the bone in patients with HIV infection. Both hips were involved in 4 of the cases. All of them were receiving highly active antiretroviral treatment when avascular necrosis of the bone was diagnosed, and 4 of them presented at least one risk factor. The risk factors found in our series were: hyperlipidemia, use of corticosteroids and alcoholism. We cannot rule out antiretroviral treatment as a risk factor for avascular necrosis of the bone. Case-control studies published have not identified antiretroviral treatment as a risk factor probably due to small size of the samples.
authors.affiliation: Unidad VIH, Hospital Universitario Doce de Octubre, Madrid, Spain. vjmorenocuerda@yahoo.es
authors.forename: V J
authors.initials: VJ
authors.lastname: Moreno-Cuerda
authors.forename: M
authors.initials: M
authors.lastname: Morales
authors.forename: L
authors.initials: L
authors.lastname: Tamargo
authors.forename: R
authors.initials: R
authors.lastname: Rubio
authors.forename: F
authors.initials: F
authors.lastname: Pulido
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010020:Osteonecrosis / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D015995:Prevalence