Necrotising, proliferative glomerulonephritis due to monoclonal cryoglobulinaemia.
Renal involvement is uncommon in the rare condition of Type I cryoglobulinaemia. On review of the literature most cases featured membranoproliferative glomerulonephritis on renal biopsy. In this case report, we describe a presentation of rapidly progressive glomerulonephritis that histologically demonstrated necrotising, proliferative glomerulonephritis. Treatment with a cytotoxic agent and corticosteroids has resulted in clinical stability.
Boudville
Neil
N
School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia. nboudvil@cyllene.uwa.edu.au
Walton
John
J
House
Andrew A
AA
D000368:Aged; D003449:Cryoglobulinemia / Q000150:complications* / Q000473:pathology / Q000628:therapy; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D006801:Humans