The effect of graded monetary reward on cognitive event-related potentials and behavior in young healthy adults.
Temporal correlates of the brain circuit underlying reward processing in healthy adults remain unclear. The current study investigated the P3 and contingent negative variation (CNV) as putative reward-related temporal markers. The effect of sustained monetary reward on these event-related potentials and on behavior was assessed using a warned reaction-time paradigm in 16 young healthy subjects. Monetary reward (0, 1 and 45 cents) varied across blocks of trials. While the CNV was unaffected by money, P3 amplitude was significantly larger for 45 than the 1 and 0 cent conditions. This effect corresponded to the monotonically positive subjective ratings of interest and excitement on the task (45>1>0). These findings suggest a difference between the P3 and CNV; the P3 is sensitive to the sustained effect of relative reward value, while the CNV does not vary with reward magnitude.
Goldstein
Rita Z
RZ
Brookhaven National Laboratory, Upton, NY 11973-5000, USA. rgoldstein@bnl.gov
Cottone
Lisa A
LA
Jia
Zhiru
Z
Maloney
Thomas
T
Volkow
Nora D
ND
Squires
Nancy K
NK
D000328:Adult; D001519:Behavior / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D003265:Contingent Negative Variation / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009042:Motivation; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012201:Reward