Validation of a model for predicting drug-induced torsades de pointes: the risky business of assessing arrhythmogenic potential.
Yamada
Kathryn A
KA
Nerbonne
Jeanne M
JM
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D010477:Perfusion; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000503:physiopathology*; D016277:Ventricular Function, Left / Q000187:drug effects*