Ultrasonographic evaluation of gallbladder functions in patients with irritable bowel syndrome.
BACKGROUND
The aim of the present study was to evaluate gallbladder function in irritable bowel syndrome (IBS) patients.


METHODS
The functions of gallbladder were investigated every 30 min for 4 h. In addition, ejection fraction of the gallbladder was calculated from the fasting and post-prandial volumes.


RESULTS
In IBS patients and healthy controls, fasting gallbladder volumes were 19.64 +/- 3.09 mL and 20.04 +/- 1.82 mL, and residual volumes after 3 h were 3.36 +/- 6.82 mL and 9.74 +/- 1.50 mL. Except for the residual volume after 3 h, all these results were not statistically significant. Residual volume after 3 h was statistically significantly lower in the IBS patients than in the controls (P < 0.001). Ejection fraction of the gallbladder was significantly higher in the IBS patients than in the controls (84% vs 55%, P < 0.001).


CONCLUSIONS
Gallbladder contraction in patients with IBS was not different from that of a control group at post-prandial second hour but was signigicantly more pronounced at the end of 3 h when compared with controls. Ejection fraction of the gallbladder was higher in IBS patients when compared with controls.
Güçlü
Mustafa
M
Department of Gastroenterology, Faculty of Medicine, Baskent University, Ankara, Turkey. mgbaskent@hotmail.com
Pourbagher
Ali
A
Serin
Ender
E
Kul
Kemal
K
Ozer
Birol
B
Cosar
Arif
A
Içer
M Okan
MO
Gür
Gürden
G
Boyacioglu
Sedat
S
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016473:Gallbladder Emptying / Q000502:physiology*; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D019518:Postprandial Period; D014463:Ultrasonography