title: [Effects of afobazole on the BDNF content in brain structures of inbred mice with different phenotypes of emotional stress reaction].
abstract: Changes in the BDNF content in brain structures--hippocampus, hypothalamus, striatum, and frontal cortex--were determined in mice of different emotional-stress reaction phenotypes, which were subjected to emotional stress and treated by the selective anxiolytic afobazole. The changes were different in BALB/c and C57BL/6 mice. Afobazole exhibited a significant protector action against a decrease in the brain BDNF level caused by emotional stress in BALB/c mice.
authors.forename: S B
authors.initials: SB
authors.lastname: Seredin
authors.forename: D S
authors.initials: DS
authors.lastname: Melkumian
authors.forename: E A
authors.initials: EA
authors.lastname: Val'dman
authors.forename: M A
authors.initials: MA
authors.lastname: Iarkova
authors.forename: T C
authors.initials: TC
authors.lastname: Seredina
authors.forename: M V
authors.initials: MV
authors.lastname: Voronin
authors.forename: A S
authors.initials: AS
authors.lastname: Lapitskaia
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001562:Benzimidazoles / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects*; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009025:Morpholines / Q000494:pharmacology*; D010641:Phenotype; D013315:Stress, Psychological / Q000378:metabolism*
chemical_list: C410924:2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole; D001562:Benzimidazoles; D019208:Brain-Derived Neurotrophic Factor; D009025:Morpholines