title: Perioperative management of a heterozygous carrier of Glanzmann's thrombasthenia submitted to coronary artery bypass grafting with cardiopulmonary bypass.
abstract: Glanzmann's thrombasthenia is a congenital hemorrhagic disorder transmitted as an autosomal recessive trait and characterized by altered production and/or assembly of the platelet membrane glycoprotein IIb/IIIa receptor. We describe the perioperative management of a heterozygous carrier of Glanzmann's thrombasthenia submitted to cardiac surgery with cardiopulmonary bypass and the case was complicated by early excessive postoperative bleeding.
authors.affiliation: Division of Cardiovascular Anesthesia and Intensive Care, Policlinico di Monza, via Amati 111, Monza (20052), Italy. valter.casati@policlinicodimonza.it
authors.forename: Valter
authors.initials: V
authors.lastname: Casati
authors.forename: Armando
authors.initials: A
authors.lastname: D'Angelo
authors.forename: Luciano
authors.initials: L
authors.lastname: Barbato
authors.forename: Edoardo
authors.initials: E
authors.lastname: Rossi
authors.forename: Maria Antonietta
authors.initials: MA
authors.lastname: Grasso
authors.forename: Salvatore
authors.initials: S
authors.lastname: Spagnolo
authors.forename: Ezio
authors.initials: E
authors.lastname: Panzeri
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D006579:Heterozygote; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000209:etiology; D013915:Thrombasthenia / Q000150:complications*; D014148:Tranexamic Acid / Q000627:therapeutic use
chemical_list: D014148:Tranexamic Acid