title: Conventional and CT angiography in children: dosimetry and dose comparisons.
abstract: Tremendous advances have been made in imaging in children with both congenital and acquired heart disease. These include technical advances in cardiac catheterization and conventional angiography, especially with advancements in interventional procedures, as well as noninvasive imaging with MR and CT angiography. With rapid advances in multidetector CT (MDCT) technology, most recently 64-detector array systems (64-slice MDCT), have come a number of advantages over MR. However, both conventional and CT angiography impart radiation dose to children. Although the presence of radiation exposure to children has long been recognized, it is apparent that our ability to assess this dose, particularly in light of the rapid advancements, has been limited. Traditional methods of dosimetry for both conventional and CT angiography are somewhat cumbersome or involve a potential for substantial uncertainty. Recent developments in dosimetry, including metal oxide semiconductor field effect transistors (MOSFET) and the availability of anthropomorphic, tissue-equivalent phantoms have provided new opportunities for dosimetric assessments. Recent work with this technology in state-of-the-art cardiac angiography suites as well as with MDCT have offered direct comparisons of doses in infants and children undergoing diagnostic cardiac evaluation. It is with these dose data that assessment of risks, and ultimately the assessment of risk-benefit, can be better achieved.
authors.affiliation: Division of Pediatric Radiology, Department of Radiology, Duke University Medical Center, 1905 McGovern-Davison Children's Health Center, PO Box DUMC 3808, Durham 27710, NC, USA. frush943@mc.duke.edu
authors.forename: Donald P
authors.initials: DP
authors.lastname: Frush
authors.forename: Terry
authors.initials: T
authors.lastname: Yoshizumi
mesh_terms: D000792:Angiography / Q000009:adverse effects / Q000706:statistics & numerical data*; D001822:Body Burden; D002648:Child; D006801:Humans; D011835:Radiation Protection / Q000379:methods*; D015641:Radiography, Interventional / Q000009:adverse effects / Q000706:statistics & numerical data*; D011874:Radiometry / Q000379:methods* / Q000706:statistics & numerical data*; D012062:Relative Biological Effectiveness; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000706:statistics & numerical data*