Electrochemical analysis of some phenothiazine derivatives--I. Chlorpromazine HCl.
In this study the electrochemical behaviour of chlorpromazine hydrochloride in sulphuric acid solutions has been examined by cyclic and linear sweep voltammetry using oxidised and non-oxidised ruthenium wire electrodes. Although a stable and permanent RuO(2) coating on the electrode took a long time to prepare, the resulting curves were highly reproducible. It was possible to study solutions in a wide concentration range only by use of scan rates lower than 20 mVs(-1). The cyclic voltammograms of chlorpromazine hydrochloride in solutions of different concentrations of sulphuric acid and the behaviour of oxidised and non-oxidised ruthenium electrodes have been compared.
Bíryol
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I
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Ankara, Turkey.
Dermís
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S