Infection and inflammation in patients on dialysis: an underlying contributor to anemia and epoetin alfa hyporesponse.
Acute or chronic infections or inflammatory conditions can exacerbate anemia in patients on dialysis. The primary goal is to identify and treat the underlying disorder, while minimizing the impact on hemoglobin (Hb) levels. Nurses can be instrumental in minimizing the impact of these conditions by monitoring the longitudinal trends in Hb levels, proactively assessing patients for inflammatory or infectious conditions, and intervening to resolve causative conditions and minimize the impact on anemia.
Breiterman-White
Randee
R
Vanderbilt University Medical Center, Nashville, TN, USA.
D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D002097:C-Reactive Protein / Q000502:physiology; D003428:Cross Infection / Q000209:etiology* / Q000517:prevention & control; D016207:Cytokines / Q000502:physiology; D016903:Drug Monitoring / Q000451:nursing; D000068817:Epoetin Alfa; D004920:Erythropoiesis / Q000187:drug effects / Q000276:immunology; D004921:Erythropoietin / Q000172:deficiency / Q000502:physiology / Q000627:therapeutic use*; D005260:Female; D006397:Hematinics / Q000627:therapeutic use*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D017053:Infection Control; D007249:Inflammation; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D024802:Nurse's Role; D009730:Nursing Assessment / Q000379:methods; D010808:Physical Examination / Q000451:nursing; D011994:Recombinant Proteins; D006435:Renal Dialysis / Q000009:adverse effects* / Q000451:nursing; D012307:Risk Factors; D017749:Total Quality Management; D017211:Treatment Failure
D016207:Cytokines; D006397:Hematinics; D006454:Hemoglobins; D011994:Recombinant Proteins; D004921:Erythropoietin; D000068817:Epoetin Alfa; D002097:C-Reactive Protein