Functionalization of solid surfaces with thermoresponsive protein-resistant films.
Pulsed plasma polymerization of N-isopropylacrylamide leads to the deposition of thermoresponsive films. The reversible (switching) behavior of these poly(N-isopropylacrylamide) surfaces has been exemplified by screening the adsorption of fibrinogen and fluorescein isothiocyanate labeled bovine serum albumin proteins by surface plasmon resonance (SPR) and fluorescence microscopy at low and elevated temperatures.
Teare
D O H
DO
Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, England, UK.
Barwick
D C
DC
Schofield
W C E
WC
Garrod
R P
RP
Beeby
A
A
Badyal
J P S
JP
D000180:Acrylic Resins / Q000138:chemical synthesis / Q000737:chemistry*; D000327:Adsorption; D000818:Animals; D008567:Membranes, Artificial; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D013499:Surface Properties; D013696:Temperature
D000180:Acrylic Resins; D008567:Membranes, Artificial; C052970:poly-N-isopropylacrylamide; D012710:Serum Albumin, Bovine