title: Phytochemical studies and antibacterial activity of Centaurium pulchellum Druce.
abstract: Two isocoumarin derivatives, one new, erythricin (1) and a known erythrocentaurin (2) were isolated from the whole plant of Centaurium pulchellum Druce. The 13C-NMR data of compound 2 are described. The structures of compounds 1, 2 were elucidated on the basis of spectral analysis including 2D-NMR experiments. Antibacterial and brine shrimp lethality assays are also described on the fractions of the plant extract.
authors.affiliation: Department of Chemistry, Gomal University, Dera Ismail Khan, Pakistan.
authors.forename: Hafsa
authors.initials: H
authors.lastname: Bibi
authors.forename: Irshad
authors.initials: I
authors.lastname: Ali
authors.forename: S K
authors.initials: SK
authors.lastname: Sadozai
authors.lastname: Atta-Ur-Rahman
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects; D029966:Centaurium / Q000737:chemistry*; D049934:Isocoumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
chemical_list: D000900:Anti-Bacterial Agents; D049934:Isocoumarins; D010936:Plant Extracts