title: Gold(I)-catalyzed intramolecular hydroamination of alkyne with trichloroacetimidates.
abstract: [reaction: see text] A study on the gold (I)-catalyzed intramolecular hydroamination of trichloroacetimidates derived from propargyl and homopropargyl alcohols is described. In the presence of 2-5 mol % of cationic Au(I) complex, a variety of trichloroacetimidates undergo efficient hydroamination under an exceptionally mild condition. An orthogonality of the current catalytic protocol with those using a stoichiometric electrophile as well as a preliminary synthetic application as a stable precursor of 2-acylamino-1,3-diene has been demonstrated.
authors.affiliation: Department of Chemistry, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Korea.
authors.forename: Ji-Eun
authors.initials: JE
authors.lastname: Kang
authors.forename: Hak-Beom
authors.initials: HB
authors.lastname: Kim
authors.forename: Jin-Woo
authors.initials: JW
authors.lastname: Lee
authors.forename: Seunghoon
authors.initials: S
authors.lastname: Shin