title: The use of methylprednisolone versus diclofenac in the treatment of inflammation and trismus after surgical removal of lower third molars.
abstract: OBJECTIVE
  To compare the efficacy of methylprednisolone (corticoid) versus diclofenac (nonsteroidal anti-inflammatory--NSAID) in the treatment of inflammation and trismus after the surgical removal of lower third molars.
  
  
  METHODS
  Prospective study on 73 patients for the surgical removal of their lower third molars. These patients were separated in two groups at random: the diclofenac group and the methylprednisolone group. A record card was filled in with preoperative and postoperative epidemiological and clinic data about inflammation and trismus (three facial measures and mouth opening). In order to make a broad study of data, BMDP program was used for statistics.
  
  
  RESULTS
  24 hours after surgery, patients in the diclofenac group showed a more severe inflammation in one of the facial measurements (<0.05). Trismus was very similar in both groups.
  
  
  CONCLUSIONS
  There were no differences in trismus depending on the antiinflammatory used. Patients in the corticoid group showed less inflammation but the difference was not as important as to justify their use.
authors.affiliation: Universidad Europea. carmen.lopez@uem.es
authors.forename: Carmen
authors.initials: C
authors.lastname: López Carriches
authors.forename: José Ma
authors.initials: JM
authors.lastname: Martínez González
authors.forename: Manuel
authors.initials: M
authors.lastname: Donado Rodríguez
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D004008:Diclofenac / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D007249:Inflammation / Q000517:prevention & control; D008775:Methylprednisolone / Q000627:therapeutic use*; D008964:Molar, Third / Q000601:surgery; D009059:Mouth Diseases / Q000517:prevention & control; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D014081:Tooth Extraction / Q000009:adverse effects*; D014313:Trismus / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000893:Anti-Inflammatory Agents; D004008:Diclofenac; D008775:Methylprednisolone