title: Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography.
abstract: A high-performance liquid chromatographic method permitted the quantitation of acetylsalicylic acid, phenylephrine, caffeine and phenacetin in tablets, and of the main impurities, salicylic acid and mono- and diacetyl derivatives of phenylephrine. A C8 reversed-phase column was used with a mobile phase containing methanol-1 M phosphoric acid-water 34:5:61 v/v/v.
authors.affiliation: Katholieke Universiteit Leuven, Instituut voor Farmaceutische Wetenschappen, Laboratorium voor Farmaceutische Chemie, Van Evenstraat 4, 3000 Leuven, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Wouters
authors.forename: E
authors.initials: E
authors.lastname: Roets
authors.forename: J
authors.initials: J
authors.lastname: Hoogmartens