title: Microcalorimetric and chromatographic investigations of the binding of some pyridine derivatives to cyclodextrins.
abstract: The binding of some pyridine derivatives to alpha-, beta- and gamma-cyclodextrins has been investigated by microcalorimetry. The strongest binding is to beta-cyclodextrin, but the binding constants are of the order 10(2) M(-1). The binding to beta-cyclodextrin was also investigated by high performance liquid chromatography. The addition of beta-cyclodextrin to the mobile phase allowed separation of molecules with similar binding constants and of racemates in the case of tropicamide.
authors.affiliation: Department of Pharmacy University of Assiut, Assiut, Egypt.
authors.forename: S
authors.initials: S
authors.lastname: El Gezawi
authors.forename: N
authors.initials: N
authors.lastname: Omar
authors.forename: N
authors.initials: N
authors.lastname: El Rabbat
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: J H
authors.initials: JH
authors.lastname: Perrin