title: Resistance training improves muscle function and body composition in patients with hyperthyroidism.
abstract: OBJECTIVE
  To evaluate the effect of resistance training on skeletal muscle performance and body composition in patients with medically treated hyperthyroidism.
  
  
  METHODS
  Nonrandomized controlled trial.
  
  
  METHODS
  Large public tertiary hospital.
  
  
  METHODS
  Sixteen sedentary patients with recent clinical diagnosis and laboratory confirmation of hyperthyroidism (7 men, 9 women; age, 38+/-11 y; weight, 58.4+/-2.6 kg; height, 1.6+/-0.3m) were assigned to the control group (medical therapy; n=9) or training group (medical therapy associated with resistance training; n=7). An age- and sex-matched healthy group served as controls (3 men, 5 women; age, 40+/-3 y; weight, 68.4+/-4.3 kg; height, 1.6+/-0.3m).
  
  
  METHODS
  Resistance training twice a week for 16 weeks.
  
  
  METHODS
  Peak muscular strength (by dynamometry and 1 repetition maximum method) and endurance (30% of peak force) for 7 movements and anthropometric measurements.
  
  
  RESULTS
  The hyperthyroid patients as a group had lower baseline overall strength values when compared with healthy subjects (200.3+/-16.0 kg vs 274.9+/-21.8 kg, respectively; P=.006). Overall absolute increases in strength (49 kg vs 91 kg, P<.05) and endurance (78.5x10(2)kg/s vs 176.9x10(2)kg/s, P<.05) were higher in the training group compared with the control group. Body weight increased in both groups, but the sum of muscular circumference increased only in the training group (training group, 92.6+/-3.3 cm vs 97.1+/-3.8 cm; control group, 94.6+/-2.2 cm vs 94.4+/-2.1cm; P<.05), with no change in the sum of skinfolds.
  
  
  CONCLUSIONS
  Resistance training accelerates the recovery of skeletal muscle function and promotes weight gain based on muscle mass improvement in patients with medically treated hyperthyroidism.
authors.affiliation: Department of Physiology and Pharmacology, Universidade Federal Fluminense, Niteroi, RJ, Brazil.
authors.forename: Kelb
authors.initials: K
authors.lastname: Bousquet-Santos
authors.forename: Mario
authors.initials: M
authors.lastname: Vaisman
authors.forename: Ney D
authors.initials: ND
authors.lastname: Barreto
authors.forename: Rubens A
authors.initials: RA
authors.lastname: Cruz-Filho
authors.forename: Bruno A
authors.initials: BA
authors.lastname: Salvador
authors.forename: Walter R
authors.initials: WR
authors.lastname: Frontera
authors.forename: Antonio C
authors.initials: AC
authors.lastname: Nobrega
mesh_terms: D000328:Adult; D001823:Body Composition; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000503:physiopathology / Q000534:rehabilitation*; D016014:Linear Models; D008297:Male; D018482:Muscle, Skeletal / Q000502:physiology; D010806:Physical Education and Training; D010807:Physical Endurance; D018709:Statistics, Nonparametric