Spongian diterpenes from Australian Nudibranchs: an anatomically guided chemical study of Glossodoris atromarginata.
An Australian population of the nudibranch mollusk Glossodoris atromarginata has been found to contain furanoditerpenes of the spongian series. Spongia-13(16),14-dien-3-one (1) and 3alpha-acetoxy-19-hydroxyspongia-13(16),14-dien-2-one [corrected] (2) were isolated for the first time from a natural source, along with a series of known diterpenes (3-7). Anatomical dissection of the animals revealed the relative distribution and chemical variation of secondary metabolites. Structural studies have provided a basis for chemical comparisons between populations from different geographic locations.
Somerville
Michael J
MJ
School of Molecular and Microbial Sciences, The University of Queensland, Brisbane QLD 4072, Australia.
Mollo
Ernesto
E
Cimino
Guido
G
Rungprom
Wimolpun
W
Garson
Mary J
MJ
D000818:Animals; D001315:Australia; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*
C513468:3beta-acetoxy-19-hydroxyspongia-13(16),14-dien-2-one; D004224:Diterpenes; C513467:spongia-13(16),14-dien-3-one