[The evaluations of concentrations IL-5 and IL-6 in toxoplasmosis].
The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 38 women aged 19-39 years infected with Toxoplasma gondii. The diagnosis was established basing on serologic examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 40 healthy women aged 18-46 years. The concentrations of IgM, IgG and IgE were assayed using a set of VIDAS (bioMerieux) according to the ELFA method. The concentrations of IL-5, IL-6 were assayed using a set of Quantikine human (R&D Systems) according to the immunoenzymatic methods with labeled antibodies. The present study revealed that in toxoplasmosis the concentration of IgE, IL-5 and IL-6 contents in blood serum was 2-times higher, than in healthy controls.
Matowicka-Karna
Joanna
J
Zakład Laboratoryjnej Diagnostyki Klinicznej, Białystok. matowic@amb.edu.pl
Kemona
Halina
H
Panasiuk
Anatol
A
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D015848:Interleukin-5 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D008875:Middle Aged; D012016:Reference Values; D014123:Toxoplasmosis / Q000276:immunology*
D015415:Biomarkers; D007074:Immunoglobulin G; D015848:Interleukin-5; D015850:Interleukin-6; D007073:Immunoglobulin E