Acute injury to the immature brain with hypoxia with or without hypoperfusion.
Hypoxia with or without hypoperfusion is a common mechanism of injury in the immature brain and can result in normal or minimally abnormal imaging studies in the first 12 hours. Often, injury progresses over time suggesting a central role for delayed cell death pathways. An awareness of the patterns of injury associated with different mechanisms of injury and the central role of delayed cell death pathways in injury evolution is important for the radiologist to understand the significance and potential outcome of these injuries.
Grant
P Ellen
PE
Division of Pediatric Radiology, Massachusetts General Hospital, Boston, MA 02114, USA. egrant2@partners.org
Yu
David
D