title: [Expression of substance P in human laryngopharynx and gastrointestine in sudden erethistic death].
abstract: OBJECTIVE
  To study the expression of substance P (SP) in human sudden erethistic death, and to seek objective morphological supports to diagnose sudden erethistic death for forensic medicine.
  
  
  METHODS
  The expression of SP was detected with immunohistochemical technique on 15 human laryngopharynx and gastrointestine of sudden erethistic death, and 20 sudden death of heart attack as control. The images of SP were analyzed by image analyzer, and the positive indexes (PI) were calculated.
  
  
  RESULTS
  SP expression in the experimental groups was significantly stronger than that in the control one (P < 0.001).
  
  
  CONCLUSIONS
  SP expression can offer an objective morphological reference support for forensic diagnosing sudden erethistic death.
authors.affiliation: School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China. shwei2002nm@yahoo.com.cn
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Sun
authors.forename: Cai-Rong
authors.initials: CR
authors.lastname: Gao
authors.forename: Gang-Mu
authors.initials: GM
authors.lastname: Ren
authors.forename: Jun-Hong
authors.initials: JH
authors.lastname: Sun
authors.forename: Jian
authors.initials: J
authors.lastname: Lu
authors.forename: Ying-Yuan
authors.initials: YY
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000378:metabolism* / Q000473:pathology; D001344:Autopsy; D002648:Child; D003645:Death, Sudden; D016757:Death, Sudden, Cardiac / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000378:metabolism; D010614:Pharynx / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*; D055815:Young Adult
chemical_list: D013373:Substance P