title: The influence of diabetes mellitus on lumbar intervertebral disk herniation.
abstract: BACKGROUND
  It has recently been proven that smoking has a negative influence on lumbar disk herniation. This is probably due to microangiopathy. Our purpose was to find out if patients operated on for lumbar disk disease also have an increased incidence of diabetes mellitus. We have also examined if this increased incidence could be the result of diagnostic uncertainties (diabetic neuropathy operated as lumbar disk disease).
  
  
  METHODS
  This is a prospective study. One hundred two patients operated on in our department for lumbar disk herniation were compared with 98 patients of the same age who were admitted for elective surgery and did not take cortisone. History for diabetes mellitus, blood glucose, and glycated hemoglobin were examined. chi(2) test was used for statistical analysis. We have also compared the results of the diabetics and nondiabetic patients operated on for lumbar disk disease.
  
  
  RESULTS
  There was a statistically significant increased incidence of diabetes mellitus in patients operated on for lumbar disk disease. There was no difference in the results at 3 months of the 2 groups of patients operated on for lumbar disk disease.
  
  
  CONCLUSIONS
  Patients operated on for lumbar disk disease have a statistically significant increased incidence of diabetes mellitus compared with similar patients operated on for other reasons. This difference cannot be explained by diagnostic uncertainties because if patients with diabetic polyneuropathy were wrongly operated on for lumbar disk disease, their results would not be as good as those of the other patients operated on for lumbar disk disease. Diabetes mellitus must be a predisposing factor in patients operated on for lumbar disk disease.
authors.affiliation: Neurosurgical Department, KAT National Hospital, Athens 14561, Greece. nicksac2@hotmail.com
authors.forename: Nick
authors.initials: N
authors.lastname: Sakellaridis
mesh_terms: D016022:Case-Control Studies; D015984:Causality; D003920:Diabetes Mellitus / Q000453:epidemiology*; D003929:Diabetic Neuropathies / Q000175:diagnosis; D003951:Diagnostic Errors; D006801:Humans; D015994:Incidence; D007405:Intervertebral Disc Displacement / Q000175:diagnosis / Q000601:surgery*; D008159:Lumbar Vertebrae; D008875:Middle Aged; D011446:Prospective Studies