title: Treatment of palmoplantar warts with a diphencyprone and salicylic acid ointment.
abstract: We report on 50 consecutive suitable patients with one or more palmoplantar warts who were treated with a patient-applied ointment comprising 0.1% diphencyprone and 15% salicylic acid in white soft paraffin. All patients sensitized to diphencyprone were followed up clinically and assessed by patient questionnaire. The intention to treat success rate in this series was 88%. The time to wart clearance ranged from less than 4 weeks to 4 months. In our patient group, 90% rated their treatment as 'excellent' or 'good', whereas 10% stated that the reaction induced by diphencyprone was 'too severe'. Our results are compared with those previously published using diphencyprone in the treatment of palmoplantar warts.
authors.affiliation: Department of Dermatology, Royal Children's Hospital, Parkville, Victoria, Australia.
authors.forename: Katherine
authors.initials: K
authors.lastname: Armour
authors.forename: David
authors.initials: D
authors.lastname: Orchard
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003521:Cyclopropanes / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D005500:Follow-Up Studies; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage*; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D020156:Salicylic Acid / Q000008:administration & dosage*; D016896:Treatment Outcome; D014860:Warts / Q000188:drug therapy*
chemical_list: D003521:Cyclopropanes; D004338:Drug Combinations; D007641:Keratolytic Agents; C029402:diphenylcyclopropenone; D020156:Salicylic Acid