title: The value of magnetic resonance imaging in diagnosis and size assessment of in situ and small invasive breast carcinoma.
abstract: BACKGROUND
  The value of magnetic resonance imaging (MRI) in diagnosis and size assessment of ductal carcinoma-in-situ (DCIS) and DCIS with small (<10 mm) invasive carcinoma was evaluated.
  
  
  METHODS
  Fifty-four patients with DCIS and 12 patients with DCIS and small invasive carcinoma were included. Mammographic (N = 64) and MRI (N = 22) images were retrospectively reviewed. Correlation coefficients were calculated to assess differences in size between imaging and histopathologic examination.
  
  
  RESULTS
  Mammographic rate of detection for DCIS was 48/52 (92%) and for DCIS with small invasive carcinoma, 10/12 (83%). MRI revealed 1 false negative case and the rate of detection for DCIS was 16/17 (94%). Correlation of mammographic size with histopathologic size was r = .44 (P < .01) and r = 0.49 (P = .03) for MRI. Mammography underestimated lesion size by 5 mm or more in 47%, whereas with MRI size was adequately assessed in 43% and overestimated in 38%.
  
  
  CONCLUSIONS
  DCIS can be visualised on MRI with high sensitivity, although tumor size can be overestimated.
authors.affiliation: Department of Surgical Oncology, Radboud University Nijmegen Medical Centre, the Netherlands.
authors.forename: Arjan P
authors.initials: AP
authors.lastname: Schouten van der Velden
authors.forename: Carla
authors.initials: C
authors.lastname: Boetes
authors.forename: Peter
authors.initials: P
authors.lastname: Bult
authors.forename: Theo
authors.initials: T
authors.lastname: Wobbes
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000175:diagnosis*; D002278:Carcinoma in Situ / Q000175:diagnosis*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D009367:Neoplasm Staging; D015203:Reproducibility of Results; D012189:Retrospective Studies