Inhibitory effects of selected Thai medicinal plants on Na+,K+-ATPase.
Extracts of ten Thai indigenous medicinal plants having ethnomedical application in the treatment of dysuria were tested for their Na(+),K(+)-ATPase inhibitory activity. The hexane extracts of Cyperus rotundus and Orthosiphon aristatus showed high potent inhibitory activity on crude enzyme Na(+),K(+)-ATPase from rat brain.
Ngamrojanavanich
Nattaya
N
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. nnattaya@chula.ac.th
Manakit
Srinual
S
Pornpakakul
Surachai
S
Petsom
Amorn
A
D000818:Animals; D001921:Brain / Q000201:enzymology*; D029786:Cyperus; D004232:Diuretics / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008519:Medicine, Traditional; D031342:Orthosiphon; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013785:Thailand
D004232:Diuretics; D010936:Plant Extracts; D000254:Sodium-Potassium-Exchanging ATPase