title: [Unique structures of Alzheimer's gamma-secretase].
authors.affiliation: Laboratory for Alzheimer's and Parkinson's Disease Research, Department of Biochemistry, Adolf-Butenandt-Institute, Ludwig-Maximilians-University, Schillerstr., 44, D-80336 Munich, Germany.
authors.forename: Keiro
authors.initials: K
authors.lastname: Shirotani
mesh_terms: D000544:Alzheimer Disease / Q000209:etiology*; D053829:Amyloid Precursor Protein Secretases; D016229:Amyloid beta-Peptides / Q000378:metabolism; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D016282:Aspartic Acid Endopeptidases; D010450:Endopeptidases / Q000737:chemistry* / Q000502:physiology*; D006801:Humans; D008563:Membrane Lipids; D008565:Membrane Proteins / Q000235:genetics; D046912:Multiprotein Complexes; D009154:Mutation; D053764:Presenilin-1; D013379:Substrate Specificity
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D008563:Membrane Lipids; D008565:Membrane Proteins; D046912:Multiprotein Complexes; C508853:PSEN1 protein, human; D053764:Presenilin-1; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human