Feasibility study concerning the use of expert systems for the development of procedures in pharmaceutical analysis.
The feasibility of using expert systems for the development of analytical procedures is investigated. A system for the computer generation of procedures to determine active drug substances in commercial formulations is proposed. It is shown that in nearly 85% of the cases investigated the present system immediately yields a correct procedure or conclusion. It is concluded that selecting methods and developing procedures with the use of expert systems is difficult but feasible.
Detaevernier
M R
MR
Pharmaceutical Institute, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.
Michotte
Y
Y
Buydens
L
L
Derde
M P
MP
Desmet
M
M
Kaufman
L
L
Musch
G
G
Smeyers-Verbeke
J
J
Thielemans
A
A
Dryon
L
L
Massart
D L
DL