Fast atom bombardment mass spectrometry in the pharmaceutical analysis of drugs.
The principles, techniques and value of fast atom bombardment mass spectrometry are summarized in this revïew. Applications of the method in such areas as molecular weight determination, standard and metabolic studies, and peptide sequencing, as well as direct quantitative analysis, are surveyed, with examples from several classes of compounds with pharmacological activity.
Bélanger
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Agriculture Canada, Centre de Recherches Alimentaires de Saint-Hyacinthe, Saint-Hyacinthe, QC, Canada J2S 4Z4.
Paré
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