title: [Valve replacement for aortic regurgitation associated with rheumatoid arthritis: a series of 5 cases].
abstract: Between 30 and 50% of patients with rheumatoid arthritis (RA) have cardiac involvement but only 2 to 10% have clinical manifestations. The authors report the results of a retrospective study of 5 cases of aortic regurgitation (AR) requiring valve replacement. There were 4 women and 1 man with an average age of 48.4 years. The average duration of the RA was 19.6 years. All patients had cardiac failure. Aortic valve replacement was performed in all cases, with bioprostheses in 4 out of 5 patients. The histopathological examination of the valves showed a rheumatoid nodule in 3 cases and non-specific lesions in one case. In the fifth patient, rheumatoid serology was positive in the pericardial effusion. The average interval between the onset of symptoms and cardiac surgery was 3.6 months (range 1 to 6 months) There were 3 deaths at 3 days, 20 months and 10 years, two patients survive after 12 and 14 years. The characteristic rapid progression of this form of AR, which may be life-threatening, should be emphasised.
authors.affiliation: Départment de Cardiologie et Maladies Vasculaires, CHU Pontchaillou, Rennes.
authors.forename: M D
authors.initials: MD
authors.lastname: Baldé
authors.forename: J E
authors.initials: JE
authors.lastname: Ecke
authors.forename: L
authors.initials: L
authors.lastname: Ortega
authors.forename: L S
authors.initials: LS
authors.lastname: Caulet-Maugendre
authors.forename: C
authors.initials: C
authors.lastname: Chabanne
authors.forename: C
authors.initials: C
authors.lastname: Almange
authors.forename: J C
authors.initials: JC
authors.lastname: Daubert
authors.forename: A
authors.initials: A
authors.lastname: Leguerrier
authors.forename: M
authors.initials: M
authors.lastname: Laurent
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000150:complications / Q000401:mortality / Q000601:surgery*; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000401:mortality; D001705:Bioprosthesis; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies