[The clinical course of microalbumiuria in 4 burn patients].
BACKGROUND
In burn patients, microvascular permeability is increased. It is difficult to decide the time to administer albumin because it may induce pulmonary edema in the re-filling period. One report shows that microalbuminuria is correlated with endothelial injury and systemic microvascular permeability.


METHODS
We measured urinary albumin/creatinine ratio (ACR) in 4 burn patients for 48 hours after injury.


RESULTS
In all patients, ACR was elevated in the early period after injury. Moreover, ACR in 2 severe burn patients with burn total body area of over 30% was above the normal range.


CONCLUSIONS
The present results show that ACR seems to be correlated with the level of microvascular permeability in 4 burn patients. We conclude that ACR may be a useful indicator to decide the time to administer albumin to a burn patient. However, further investigation is required to decide the threshold value of ACR in a severe burn patient whose ACR are kept above the normal range in the long-term.
Ando
Yuko
Y
Department of Anesthesia, Nagasaki Rousai Hospital, Sasebo 857-0134.
Terao
Yoshiaki
Y
Yamashita
Kazunori
K
Fujinaga
Arihiro
A
Tanabe
Takahiro
T
Fukusaki
Makoto
M
D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000652:urine*; D002056:Burns / Q000652:urine*; D002199:Capillary Permeability; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D003404:Creatinine