title: [Cluster like headache in a patient with the Maffucci's syndrome].
abstract: Maffucci's syndrome is a rare congenital, nonhereditary mesodermal dysplasia characterized by soft tissue hemangiomas and multiple enchondromas. A 52 years old man was diagnosised as Maffucci's syndrome in his childhood. He complained of mild paraesthesia which gradually progressed to intolerable pain lasting one to two houres with rhinorrhea (cluster like headache). Magnetic resonance imaging showed a pituitary adenoma which invaded into right cavernous sinus. Serum hormone level was almost normal, therefore we diagnosed nonfunctional pituitary adenoma. The pharmacological preventive treatments for headache, such as loxoprofen, sumatriptan, lomerizine had no effect. On the other hand, verapamil showed moderate improvement of his headache, then the symptons was gradually getting better and finally he felt no pain. This case demonstrated occurence mechanism of cluster headache and preventive effect of verapamil associated with cavernous sinus.
authors.affiliation: Department of Neurology, Shizuoka Red Cross Hospital, 8-2 Otemachi, Aoi-ku, Shizuoka City 420-0853, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Kitamura
authors.forename: Noboru
authors.initials: N
authors.lastname: Imai
authors.forename: Takashi
authors.initials: T
authors.lastname: Konisi
authors.forename: Youji
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Serizawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Okabe
mesh_terms: D000236:Adenoma / Q000150:complications; D003027:Cluster Headache / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control; D004687:Enchondromatosis / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications; D014665:Vasodilator Agents / Q000627:therapeutic use*; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D014700:Verapamil