title: Anetoderma occurring after hepatitis B vaccination.
abstract: Anetoderma is an elastolytic disorder of unknown origin. To our knowledge, anetoderma secondary to hepatitis B immunization has been described only once in the literature, in two siblings vaccinated at the same time. We describe, what we believe to be an additional case of such a rare disorder in a 21-year-old man. He presented with white spots and papules on his neck, upper limbs and trunk, that had developed gradually within the last 6 years without any symptoms. The initial lesions were red macules, which gradually enlarged in size and number, becoming pale. Biopsy of a sack-like lesion revealed normal epidermis and a discrete mononuclear infiltrate throughout the dermis. Association of anetoderma with hepatitis B vaccination is speculated here, as suggested by history of vaccination two weeks prior to the onset of skin eruption and ruling out other possible causes of anetoderma.
authors.affiliation: Department of Dermatology, Hospital Geral de Santo Antonio, Porto, Portugal. martamotateixeira@mail.telepac.pt
authors.forename: Marta
authors.initials: M
authors.lastname: Teixeira
authors.forename: Rosario
authors.initials: R
authors.lastname: Alves
authors.forename: Aurea
authors.initials: A
authors.lastname: Canelhas
authors.forename: Manuela
authors.initials: M
authors.lastname: Selores
mesh_terms: D000328:Adult; D002465:Cell Movement / Q000276:immunology; D003238:Connective Tissue / Q000276:immunology / Q000473:pathology*; D004547:Elastic Tissue / Q000276:immunology / Q000473:pathology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000473:pathology; D008297:Male; D012871:Skin Diseases / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology*
chemical_list: D017325:Hepatitis B Vaccines