title: [Rats of Krushinsky-Molodkina strain: studies of audiogenic epilepsy, vascular pathology, and behavior].
abstract: Physiological, biochemical and genetic studies of audiogenic epilepsy in Krushinsky-Molodkina (KM) rat strain are analyzed. In brief, the history of KM strain selection and its current state are reviewed. Physiological mechanisms of the typical audiogenic seizure development and the audiogenic myoclonus (audiogenic kindling phenomena) are considered. The EEG correlates of these phenomena are presented. Biochemical features of the strain (neurotransmitter and neuronal membrane biochemistry) are described.
authors.forename: A F
authors.initials: AF
authors.lastname: Semiokhina
authors.forename: I B
authors.initials: IB
authors.lastname: Fedotova
authors.forename: I I
authors.initials: II
authors.lastname: Poletaeva
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000098:blood supply* / Q000378:metabolism / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D004195:Disease Models, Animal; D004831:Epilepsies, Myoclonic / Q000209:etiology / Q000503:physiopathology; D020195:Epilepsy, Reflex / Q000209:etiology / Q000235:genetics / Q000503:physiopathology*; D049673:History, 20th Century; D007178:Inbreeding; D007696:Kindling, Neurologic; D008563:Membrane Lipids / Q000378:metabolism; D009207:Myoclonus / Q000209:etiology / Q000503:physiopathology; D018377:Neurotransmitter Agents / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000209:etiology / Q000503:physiopathology
chemical_list: D008563:Membrane Lipids; D018377:Neurotransmitter Agents