title: Prognostic factor analysis and proposed prognostic model for conventional treatment of high-grade primary gastric lymphoma.
abstract: OBJECTIVE
  We conducted a clinical risk factors analysis to define a prognostic model for high-grade primary gastric lymphoma (HG-PGL).
  
  
  RESULTS
  The median event-free survival and overall survival of 214 HG-PGL patients were 54 and 104.5 months, respectively, after a median follow-up duration of 60 months. According to the prognostic factor analysis, survival, advanced age, male gender, higher LDH levels and the presence of ascites were identified as independent prognostic factors for HG-PGL. We identified four groups at different risk: group 1, no adverse effect; group 2, one factor; group 3, two factors; group 4, three or four factors. The new prognostic model showed excellent prognostic capacity to differentiate subgroups according to their risk stratification.
  
  
  CONCLUSIONS
  The proposed new prognostic model for HG-PGL demonstrated a balanced distribution of patients into four groups with good prognostic capacity.
authors.affiliation: Department of Hematology-Oncology, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea.
authors.forename: Yeon H
authors.initials: YH
authors.lastname: Park
authors.forename: Won S
authors.initials: WS
authors.lastname: Kim
authors.forename: Soo M
authors.initials: SM
authors.lastname: Bang
authors.forename: Soon I
authors.initials: SI
authors.lastname: Lee
authors.forename: Ji E
authors.initials: JE
authors.lastname: Uhm
authors.forename: Hye J
authors.initials: HJ
authors.lastname: Kang
authors.forename: Im I
authors.initials: II
authors.lastname: Na
authors.forename: Sung H
authors.initials: SH
authors.lastname: Yang
authors.forename: Seung-Sook
authors.initials: SS
authors.lastname: Lee
authors.forename: Kihyun
authors.initials: K
authors.lastname: Kim
authors.forename: Chul W
authors.initials: CW
authors.lastname: Jung
authors.forename: Keunchil
authors.initials: K
authors.lastname: Park
authors.forename: Young H
authors.initials: YH
authors.lastname: Ko
authors.forename: Baek-Yeol
authors.initials: BY
authors.lastname: Ryoo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011379:Prognosis; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*