title: Polymer-bound dirhodium tetracarboxylate films for fluorescent detection of nitric oxide.
abstract: A polymer-bound dirhodium complex, [{Rh2(O2CCH3)3(Ds-pip)}n(O2C-P)], was prepared via ligand exchange of [Rh2(O2CCH3)4] with the side chains of a methyl methacrylate/methacrylic acid copolymer (O2C-P) followed by axial coordination of the fluorophore, N-dansylpiperazine (Ds-pip). Emission from Ds-pip is quenched when coordinated to the dirhodium complex but can be restored upon displacement by analytes. Exposure of [{Rh2(O2CCH3)3(Ds-pip)}n(O2C-P)] films to aqueous nitric oxide (NO) evokes a 2.2-fold increase in integrated emission. The polymer matrix excludes potentially interfering analytes including reactive oxygen or nitrogen species, which cannot readily permeate the film.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
authors.forename: Rhett C
authors.initials: RC
authors.lastname: Smith
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Tennyson
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Lippard
mesh_terms: D002264:Carboxylic Acids; D005453:Fluorescence; D009569:Nitric Oxide / Q000032:analysis*; D011108:Polymers; D012238:Rhodium
chemical_list: D002264:Carboxylic Acids; D011108:Polymers; D009569:Nitric Oxide; D012238:Rhodium