title: Epithelioid hemangioendothelioma derived from the spine region: case report and review of the literature.
abstract: Epithelioid hemangioendotheliomas (EHE) are rare vascular tumors which generally originate from soft tissues and visceral organs. Primary bone EHEs, especially those occurring in the spine region, are extremely rare. Our case is that of a 30-year-old man who was admitted to hospital with low back pain, difficulty in walking, post-voiding urinary incontinence and numbness in the caudal area. X-ray showed a lytic process affecting the vertebra L2 and collapse of L1. Vertebrectomy of L1 and gross total tumor resection were performed. Histopathological and immunohistochemical findings of the tumor tissue supported the diagnosis of EHE. The case, which to the best of our knowledge is only the fifth such reported case, is presented with its clinicopathological findings and a review of the literature.
authors.affiliation: Department of Pathology, Akdeniz University Faculty of Medicine, Antalya, Turkey. guzidegokhan@akdeniz.edu.tr
authors.forename: Guzide Ayse
authors.initials: GA
authors.lastname: Gokhan
authors.forename: Mahmut
authors.initials: M
authors.lastname: Akyuz
authors.forename: Inanc Elif
authors.initials: IE
authors.lastname: Gurer
authors.forename: Recai
authors.initials: R
authors.lastname: Tuncer
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis*; D006801:Humans; D008297:Male; D035583:Rare Diseases / Q000175:diagnosis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*; D013125:Spinal Neoplasms / Q000175:diagnosis*