Amination of CF3-enones with nosyloxycarbamates.
CF3-enones showed a different reactivity in amination reactions with nosyloxycarbamates. 4-Oxazolines or vinyl carbamates were obtained as unique products depending on the nature of double-bond substituents and on the choice of carbamates and bases. Starting from trans-trifluoroacetyl olefins carrying a heterocyclic residue or the p-methoxyphenyl group on the double bond, a rare loss of CF3CO was observed when the aminations were performed under heterogeneous conditions using CaO as the base.
Colantoni
Daniele
D
Dipartimento di Chimica, Università degli Studi "La Sapienza", P.le Aldo Moro 2, I-00185 Roma, Italy.
Fioravanti
Stefania
S
Pellacani
Lucio
L
Tardella
Paolo A
PA