Are human CETP mutations and CETP-inhibiting drugs a good or a bad deal?
Luft
Friedrich C
FC
Franz Volhard Clinic, HELIOS Kliniken Berlin, Medical Faculty of the Charité, Humboldt University, Wiltbergstrasse 50, 13125 Berlin-Buch, Germany. luft@fvk-berlin.de
D000577:Amides; D000818:Animals; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D016632:Apolipoprotein A-I / Q000097:blood; D001692:Biological Transport; D002784:Cholesterol / Q000097:blood / Q000378:metabolism*; D053480:Cholesterol Ester Transfer Proteins / Q000037:antagonists & inhibitors / Q000235:genetics*; D008076:Cholesterol, HDL / Q000097:blood; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D004952:Esters; D006579:Heterozygote; D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood / Q000000981:diagnostic imaging / Q000235:genetics; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008099:Liver / Q000378:metabolism; D008875:Middle Aged; D009154:Mutation; D016032:Randomized Controlled Trials as Topic; D013438:Sulfhydryl Compounds / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D014280:Triglycerides / Q000097:blood
D000577:Amides; D000924:Anticholesteremic Agents; D016632:Apolipoprotein A-I; C506642:CETP protein, human; D053480:Cholesterol Ester Transfer Proteins; D008076:Cholesterol, HDL; D004952:Esters; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D013438:Sulfhydryl Compounds; D014280:Triglycerides; C411602:dalcetrapib; D002784:Cholesterol