DNA functionalized single-walled carbon nanotubes for electrochemical detection.
Single-walled carbon nanotubes (SWNTs) were effectively dispersed and functionalized by wrapping with single-stranded DNA (ssDNA). The ssDNA-SWNTs attach strongly on glass substrate and easily form a uniform film, making it possible for electrochemical analysis and sensing. The film was fabricated into a working electrode, which exhibited good electrochemical voltammetric properties, such as flat and wide potential window, well-defined quasi-reversible voltammetric responses, and quick electron transfer for a Fe(CN)6(3-)/Fe(CN)6(4) system, indicating that the ssDNA-SWNTs film should be a good analytical electrode for electrochemical detection or sensing. This was demonstrated by highly selective and sensitive detection of a low concentration of dopamine in the presence of excess ascorbic acid.
Hu
Chenguo
C
Department of Applied Physics, Chongqing University, Chongqing 400044, China.
Zhang
Yiyi
Y
Bao
Gang
G
Zhang
Yuelan
Y
Liu
Meilin
M
Wang
Zhong Lin
ZL
D002244:Carbon; D004247:DNA / Q000032:analysis* / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D008958:Models, Molecular; D036103:Nanotechnology / Q000379:methods*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*
D009838:Oligodeoxyribonucleotides; D002244:Carbon; D004247:DNA