Anomalous reflection of gold applicable for a practical protein-detecting chip platform.
A simple, convenient and label-free fiber optic detection system based on the characteristic property, 'anomalous reflection (AR)' of gold was developed and preliminary experiments showed that the AR signals were sensitive enough to monitor protein-peptide interactions on solid surfaces.
Watanabe
Sinya
S
The COE21 Program and Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
Usui
Kenji
K
Tomizaki
Kin-ya
KY
Kajikawa
Kotaro
K
Mihara
Hisakazu
H
D000595:Amino Acid Sequence; D015374:Biosensing Techniques; D017979:Gold Colloid / Q000737:chemistry*; D046208:Microchip Analytical Procedures; D008969:Molecular Sequence Data; D040081:Protein Array Analysis; D025941:Protein Interaction Mapping; D011506:Proteins / Q000737:chemistry; D020349:Surface Plasmon Resonance / Q000379:methods*
D017979:Gold Colloid; D011506:Proteins