title: Paediatric central nervous system tumours in a New Zealand population: a 10-year experience of epidemiology, management strategies and outcomes.
abstract: We analysed 166 cases of paediatric central nervous system tumour presenting to Auckland City and Starship Children's Hospital, New Zealand, between 1995 and 2004. The purpose of this study was to perform an audit of paediatric neurosurgical practice in the upper North Island of New Zealand with the objective of assessing patient presentation, demographics, and modality and efficacy of therapy. The overall incidence of central nervous system tumours was 3.42/100,000/year. The incidence rate of medulloblastoma for Maori was over double that for European New Zealanders. Tumour clearance was attempted in 81.3% of patients. Some type of adjunct therapy was received by 45.2% of patients. Overall, 60.8% of patients had satisfactory or good results. Survival rates for pilocytic astrocytoma and ependymoma were consistent with previous studies. Survival data for medulloblastoma demonstrate improved outcomes with complete resection of tumour and with a specialist paediatric neurosurgeon compared with general neurosurgeons. Recent management changes have led to improved outcomes.
authors.affiliation: Department of Neurosurgery, Auckland City Hospital and Starship Children's Hospital, The University of Auckland, Park Road, Grafton, Private Bag 92024, Auckland, New Zealand. smonty@ihug.co.nz
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Monteith
authors.forename: Peter A
authors.initials: PA
authors.lastname: Heppner
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Woodfield
authors.forename: Andrew J J
authors.initials: AJ
authors.lastname: Law
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D016543:Central Nervous System Neoplasms / Q000453:epidemiology* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005006:Ethnicity; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009520:New Zealand / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D010372:Pediatrics; D012189:Retrospective Studies; D017678:Sex Distribution