title: Statin use before by-pass surgery decreases the incidence and shortens the duration of postoperative atrial fibrillation.
abstract: BACKGROUND
  The aim of the present observational study is to search the incidence of postoperative atrial fibrillation (AF) in patients with or without preoperative statin treatment.
  
  
  RESULTS
  The population consisted of 362 consecutive patients (267 on and 95 not on statin). Diabetes mellitus was more frequent in statin group (p = 0.03). Other demographic and procedural variables were similar in the both groups (All p > 0.05). Postoperative AF was less frequent and its duration was shorter in statin group compared to non-statin group (p = 0.03 and 0.0001, respectively). The Kaplan-Meier analysis showed the protective effect of statins against the risk of developing AF (p = 0.01).
  
  
  CONCLUSIONS
  Statin treatment before the by-pass surgery decreases the incidence and shortens the duration of postoperative AF.
authors.affiliation: Departments of Cardiology and Cardiovascular Surgery, Suleyman Demirel University Medical School, Isparta, Turkey. mehmetozaydin@hotmail.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozaydin
authors.forename: Abdullah
authors.initials: A
authors.lastname: Dogan
authors.forename: Ercan
authors.initials: E
authors.lastname: Varol
authors.forename: Sahin
authors.initials: S
authors.lastname: Kapan
authors.forename: Nurullah
authors.initials: N
authors.lastname: Tuzun
authors.forename: Oktay
authors.initials: O
authors.lastname: Peker
authors.forename: Suleyman M
authors.initials: SM
authors.lastname: Aslan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Altinbas
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ocal
authors.forename: Erdogan
authors.initials: E
authors.lastname: Ibrisim
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015994:Incidence; D007249:Inflammation; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012306:Risk
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors