title: [Actinic keratosis].
abstract: Actinic keratosis is a precancerous lesion that is commonly seen in the elderly patient and requires treatment. It shows a predilection for areas of the skin that are exposed to the sun, and usually manifests as multiple skin-colored or discrete reddish scaly verrucous plaques. The diagnosis is usually based on the clinical appearance of the lesion. Therapeutic options include physical, immunological and chemical measures. The choice of treatment is determined by numerous factors, and can be adapted to the individual situation presenting.
authors.affiliation: Klinik und Poliklinik für Dermatologie, Universitätsklinikum Essen. joachimdissemond@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Dissemond
authors.forename: S
authors.initials: S
authors.lastname: Grabbe
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use; D000367:Age Factors; D000368:Aged; D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D017679:Cryotherapy; D003937:Diagnosis, Differential; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D000077271:Imiquimod; D007369:Interferon Inducers / Q000008:administration & dosage / Q000627:therapeutic use; D007642:Keratosis / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D053685:Laser Therapy; D008297:Male; D009824:Ointments; D010778:Photochemotherapy; D011230:Precancerous Conditions / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D012307:Risk Factors; D012878:Skin Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*
chemical_list: D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D007369:Interferon Inducers; D009824:Ointments; D000077271:Imiquimod; D005472:Fluorouracil