Canine renal failure syndrome in three dogs.
Three dead dogs were brought to the College of Veterinary Medicine, Kyungpook National University for study. Clinically, all the dogs showed emaciation, anorexia, depression, hemorrhagic vomiting and diarrhea for 7-10 days before death. All the clinical signs were first noted for about one month after feeding the dogs with commercial diets. At necropsy, all 3 dogs had severe renal damage with the same green-yellowish colored nephroliths in the renal pelvis. They also showed systemic hemorrhage and calcification of several organs, which might have been induced by uremia. Microscopically, necrosis, calcification and calculi were detected in the renal tubules, and especially in the proximal convoluted tubules and collecting ducts of the kidney. These findings were supportive of a mycotoxic effect, and especially on their kidneys. However, the precise cause of the toxic effect in these cases of canine renal failure could not be determined.
Jeong
Won Il
WI
Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea.
Do
Sun Hee
SH
Jeong
Da Hee
DH
Chung
Jae Yong
JY
Yang
Hai Jie
HJ
Yuan
Dong Wei
DW
Hong
Il Hwa
IH
Park
Jin Kyu
JK
Goo
Moon Jung
MJ
Jeong
Kyu Shik
KS
D058186:Acute Kidney Injury / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000382:microbiology / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D008297:Male; D015651:Mycotoxicosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*