title: Effect of cigarette smoke on body weight, food intake and reproductive organs in adult albino rats.
abstract: One hour daily exposure to cigarette smoke for two months significantly decreased the body weight and food intake in male and female albino rats. The latency for conception increased significantly and the litter size decreased. Mortality rate per litter increased and grayish discoloration of the skin in the experimental group was the only congenital anomaly seen. Testes and ovaries showed a significant decrease in weight. The stroma of the ovaries were occupied by very few Graafian follicles. Testes showed disruption of the normal orderly progression of the spermatogonia. The tubules showed only one layer of spermatogonia and very few germinal cells. The number of sperms was less in the testes. The results show that exposure to cigarette smoke is detrimental to the reproductivity in both, male and female albino rats.
authors.affiliation: Department of Physiology, Goa Medical College, Bambolim Goa, 403 202, India. shamaudi@dataone.in
authors.forename: Sumedha S
authors.initials: SS
authors.lastname: Audi
authors.forename: Marjorie E
authors.initials: ME
authors.lastname: Abraham
authors.forename: Abhaya S
authors.initials: AS
authors.lastname: Borker
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D004435:Eating / Q000187:drug effects*; D030762:Estrous Cycle / Q000187:drug effects; D005260:Female; D005836:Genitalia, Female / Q000187:drug effects* / Q000473:pathology; D005837:Genitalia, Male / Q000187:drug effects* / Q000473:pathology; D008098:Litter Size; D008297:Male; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution