title: Laboratory assessment of kidney function.
abstract: It is important to be able to accurately predict the function of the kidneys by estimating GFR. GFR is a strong predictor for the onset and complications of CKD and it also allows us to dose-adjust medications. It, unfortunately, cannot be measured directly, so we have to depend on surrogate markers such as creatinine to estimate it. With the development of newer predictive equations such as the MDRD equations, we can more accurately estimate GFR in certain populations.
authors.affiliation: London Health Sciences Centre, London, Ontario. Seadna.Ledger@lhsc.on.ca
authors.forename: Séadna
authors.initials: S
authors.lastname: Ledger
mesh_terms: D000328:Adult; D000367:Age Factors; D001806:Blood Urea Nitrogen; D001827:Body Height; D049628:Body Size; D002648:Child; D003404:Creatinine / Q000378:metabolism; D055316:Cystatin C; D015891:Cystatins / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism* / Q000503:physiopathology / Q000628:therapy; D007677:Kidney Function Tests / Q000379:methods* / Q000592:standards; D008297:Male; D008657:Metabolic Clearance Rate; D011507:Proteinuria / Q000209:etiology; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D012727:Sex Characteristics
chemical_list: C525030:CST3 protein, human; D055316:Cystatin C; D015891:Cystatins; D003404:Creatinine