Kinetic-spectrophotometric method for the assay of copper(II) in human serum by catalytic oxidation of salicylic acid.
A very sensitive kinetic spectrophotometric method for the determination of copper(II) concentrations as low as 0.07 ng ml(-1) is described. This method is based on the oxidation of salicylic acid by hydrogen peroxide in ammoniacal medium, catalysed by copper(II) ion. The figures of merit of the procedure and the results of a study of interferences are given. The method is applied to the assay of copper in human blood serum.
Casassas
E
E
Department of Analytical Chemistry, Universitat de Barcelona, Av. Diagonal 647, 08028 Barcelona, Spain.
Puignou
L
L
Izquierdo-Ridorsa
A
A
Pedrola
M
M