title: Spectrum of bone tumors in Chiang Mai University Hospital, Thailand according to WHO classification 2002: A study of 1,001 cases.
abstract: OBJECTIVE
  The aim of the present study was to determine the spectrum, frequency and demographics of bone tumors.
  
  
  METHODS
  A retrospective study of the 1,001 bone tumor specimens from the files at the Pathology Department of the Chiang Mai University Hospital, Thailand from 2000 to 2004.
  
  
  RESULTS
  From the study, 41 were non-neoplastic mass lesions, and 960 were neoplastic, with 856 (89%) as primary and 104 (11%) as metastatic tumors. In the primary tumor group, 654 (76%) cases were of hematologic origin, and 202 (24%) were non-hematologic. The most common benign bone tumors were giant cell tumor (n = 37), osteochondroma (n = 25), and chondroma (n = 15). The most common malignant bone tumors were lymphoma-leukemia (n = 583), metastatic malignancy (n = 104), plasma cell myeloma (n = 71), and osteosarcoma (n = 58).
  
  
  CONCLUSIONS
  The present study showed a higher frequency of osteosarcoma (68%), lower frequencies of chondrosarcoma (12%) and Ewing sarcoma (4%) among primary non-hematologic malignant bone tumors when compared with similar studies based on Western patients. Whether these differences reflect differences in the ethnic population or in practice patterns remains to be determined
authors.affiliation: Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. jsettako@mail.med.cmu.ac.th
authors.forename: Jongkolnee
authors.initials: J
authors.lastname: Settakorn
authors.forename: Suree
authors.initials: S
authors.lastname: Lekawanvijit
authors.forename: Olarn
authors.initials: O
authors.lastname: Arpornchayanon
authors.forename: Samreung
authors.initials: S
authors.lastname: Rangdaeng
authors.forename: Pramote
authors.initials: P
authors.lastname: Vanitanakom
authors.forename: Sarawut
authors.initials: S
authors.lastname: Kongkarnka
authors.forename: Ruangrong
authors.initials: R
authors.lastname: Cheepsattayakorn
authors.forename: Charin
authors.initials: C
authors.lastname: Ya-In
authors.forename: Paul S
authors.initials: PS
authors.lastname: Thorner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005870:Giant Cell Tumors / Q000175:diagnosis / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015831:Osteochondroma / Q000175:diagnosis / Q000453:epidemiology; D012516:Osteosarcoma / Q000175:diagnosis / Q000453:epidemiology; D012189:Retrospective Studies; D013785:Thailand / Q000453:epidemiology; D014944:World Health Organization