title: Application of potassium titanyl phosphate (KTP) laser delivered via bronchofiberscope in the treatment of endobronchial tuberculosis.
abstract: To explore the application of potassium titanyl phosphate (KTP) laser delivered via bronchofiberscope in the treatment of endobronchial tuberculosis. 36 patients with a diagnosis of endobronchial tuberculosis, with age ranging from 15 to 40 y were treated with KTP laser between Dec. 2002 and July 2004 (designated as treatment group). The other 36 patients diagnosed as having endobronchial tuberculosis (aged 18 to 42 y, with a mean age of 33. 5 y) without having received KTP laser treatment were included in a control group. Our results showed that the effective rates, in terms of recovery of bronchial lumen and cleanup of caseous necrotic mass were significantly higher in the treatment group 8 weeks after the treatment (P<0.01), and the healing rates of atelectasis and obstructive infection were also significantly higher in the treatment group (P<0.05 and P<0.01), but the incidence of complication after 8 weeks was no significant difference (P >0.05). No significant changes were found in SaO2 and HR before, during and after the operation in the treatment group (P>0.05). It is concluded that KTP laser is an effective therapy for endobronchial tuberculosis.
authors.affiliation: Department of General Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Caiping
authors.initials: C
authors.lastname: Li
authors.forename: Qiusheng
authors.initials: Q
authors.lastname: Jing
authors.forename: Weiwei
authors.initials: W
authors.lastname: Yu
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D001982:Bronchial Diseases / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods*; D008297:Male; D010710:Phosphates; D014025:Titanium; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000473:pathology / Q000601:surgery*
chemical_list: D010710:Phosphates; C064806:potassium titanylphosphate; D014025:Titanium