title: Ovarian tissue cryopreservation and transplantation: a review.
abstract: The review covers current options for ovarian tissue cryopreservation and transplantation and provides a systematic review of the existing literature from the last 10 years, taking into account all previously published reviews on the subject. The different cryopreservation options available for fertility preservation in cancer patients are embryo cryopreservation, oocyte cryopreservation and ovarian tissue cryopreservation. The choice depends on various parameters: the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status. The different options and their results are discussed, as well as their putative indications and efficacy. The review concludes that advances in reproductive technology have made fertility preservation techniques a real possibility for patients whose gonadal function is threatened by premature menopause, or by treatments such as radiotherapy, chemotherapy or surgical castration.
authors.affiliation: Department of Gynecology, Université Catholique de Louvain, Brussels, Belgium. donnez@gyne.ucl.ac.be
authors.forename: Jacques
authors.initials: J
authors.lastname: Donnez
authors.forename: Belen
authors.initials: B
authors.lastname: Martinez-Madrid
authors.forename: Pascale
authors.initials: P
authors.lastname: Jadoul
authors.forename: Anne
authors.initials: A
authors.lastname: Van Langendonckt
authors.forename: Dominique
authors.initials: D
authors.lastname: Demylle
authors.forename: Marie-Madeleine
authors.initials: MM
authors.lastname: Dolmans
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D015925:Cryopreservation / Q000941:ethics / Q000592:standards; D004622:Embryo, Mammalian; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D009865:Oocytes; D006080:Ovarian Follicle; D010053:Ovary / Q000473:pathology / Q000637:transplantation; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents