title: History of aldosterone on its 50th birthday.
abstract: The paper describes the impact of mineralocorticoid substances on water regulation from Theophrastus (IV century B.C.) to Thomas Addison (1849). It also opens to the missed discovery of aldosterone of I.A. Macchi.
authors.affiliation: Department of Medical and Surgical Sciences, University of Padua, Italy. cristina.fiore@unipd.it
authors.forename: Cristina
authors.initials: C
authors.lastname: Fiore
authors.forename: Lorenzo A
authors.initials: LA
authors.lastname: Calò
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Colombo
authors.forename: Clarence E
authors.initials: CE
authors.lastname: Grimm
authors.forename: Decio
authors.initials: D
authors.lastname: Armanini
mesh_terms: D000450:Aldosterone / Q000737:chemistry / Q000266:history* / Q000302:isolation & purification / Q000502:physiology; D001834:Body Water / Q000378:metabolism; D049672:History, 19th Century; D049673:History, 20th Century; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
chemical_list: D000450:Aldosterone; D012964:Sodium; D011188:Potassium