Changes in plasma catecholamine concentration during salinity manipulation and anaesthesia in the hagfish Eptatretus cirrhatus.
Plasma catecholamines were measured following surgery under anaesthesia and after exposing hagfish to 90 and 110% sea water (SW). Plasma noradrenaline (NA) concentration increased from a resting value of 7 to 818 nM l(-1) on anaesthesia. Plasma adrenaline (AD) did not change. NA concentrations also increased during volume depletion (110% SW), but to much lower values (26 nM l(-1 )at 100 min). AD concentrations were increased at 20 min, then fell. During volume loading (90% SW) NA fell, and AD increased to a maximum concentration of 511 nM l(-1) at 40 min (resting concentration 24 nM l(-1)). The data are consistent with a vasoconstrictory role for NA on central veins when venous pressures fall and a vasodilatory role for AD on volume expansion.
Foster
J M
JM
School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch 8020, New Zealand.
Forster
M E
ME
D000758:Anesthesia / Q000662:veterinary; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D001566:Benzocaine / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D001810:Blood Volume / Q000187:drug effects / Q000502:physiology; D003243:Consciousness / Q000187:drug effects / Q000502:physiology; D004837:Epinephrine / Q000097:blood*; D006196:Hagfishes / Q000097:blood*; D006400:Hematocrit; D009638:Norepinephrine / Q000097:blood*; D009994:Osmolar Concentration; D012623:Seawater / Q000737:chemistry; D012965:Sodium Chloride / Q000032:analysis; D014661:Vasoconstriction; D014882:Water-Electrolyte Balance / Q000502:physiology
D000779:Anesthetics, Local; D012965:Sodium Chloride; D001566:Benzocaine; D009638:Norepinephrine; D004837:Epinephrine