[The evaluation of concentrations IL-5 and IL-6 in echinococcosis].
The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 24 patients (19 women and 5 men) aged 26-69 years infected with Echinococcus granulosus. The diagnosis was established basing on serological examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 40 healthy people (22 women and 18 men) aged 20-45 years. The concentration of IgE were assayed using a set of VIDAS (the ELFA method). The concentration of IL-5, IL-6 were assayed using a set of Quantikine human (R&D Systems). The study demonstrated that in echinococcosis the concentrations of IgE, IL-5 and IL-6 contents in blood serum was higher 10-, 2- and 3-times, respectively than in healthy controls.
Matowicka-Karna
Joanna
J
Zakład Laboratoryjnej Diagnostyki Klinicznej, Akademia Medyczna, Białystok. matowic@amb.edu.pl
Kemona
Halina
H
Panasiuk
Anatol
A
D000328:Adult; D000368:Aged; D000909:Antibodies, Helminth / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D004443:Echinococcosis / Q000276:immunology* / Q000469:parasitology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D015848:Interleukin-5 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values
D000909:Antibodies, Helminth; D015415:Biomarkers; D015848:Interleukin-5; D015850:Interleukin-6; D007073:Immunoglobulin E