[The effect of prostaglandin E1 infusion on circulating system in patients undergoing surgical procedure because of abdominal aortic aneurysm].
OBJECTIVE
was to assess the effect of PGE1 infusion on cardiovascular system in patients undergoing reconstructive operation because of abdominal aortic aneurysm.


METHODS
The study group consisted of 54 patients divided into control group and examined group. Patients of the examined group were additionally receiving PGE1 (Prostavasin) in continous intravenous infusion in dose 0.02 mg/kg b.m./min. During surgical procedure the cardiovascular system was being monitored by the measurement the heart rate, systolic pressure and central venous pressure. The parameters were measured twice: at the begining of the operation and after anastomosis.


RESULTS
We have noticed that the heart rate and systolic pressure were significantly lower in patients from the examined group.


CONCLUSIONS
Thus it seems that administration of PGE1 during prosthetic restoration can favorably influence general condition of patients and diminish the perioperative risk.
Józefowicz
Agata
A
Uniwersytet Medyczny w Lodzi, Wojewódzki Specjalistyczny Szpital im M Pirogowa, Oddział Anestezjologii i Intensywnej Terapii.
Masierek
Andrzej
A
Brzezińska-Błaszczyk
Ewa
E
D000368:Aged; D000527:Alprostadil / Q000008:administration & dosage*; D017544:Aortic Aneurysm, Abdominal / Q000188:drug therapy* / Q000601:surgery*; D001794:Blood Pressure / Q000187:drug effects*; D002496:Central Venous Pressure / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative
D000527:Alprostadil