[Hyperhomocysteinemia in patients with atherosclerotic extracranial disease of the carotid artery].
Only few papers analyze the factors increasing the narrowing of the internal carotid artery (ICA), i.e. the factors associated with the progression of atherosclerosis and the subsequent cerebral circulatory disorder. The authors show a relationship between homocysteine, other risk factors, and the degree of ICA narrowing. The latter is shown to be directly related to the increment of homocysteine levels (odds ratio (OR) 19, 95% confidence interval) (CI) 11 to 60). The level of homocysteine is directly related to coronary heart disease (OR 9.2, 95% CI 2.3 to 21), stroke with major neurological deficit (OR 10.4, 95% CI 1.1 to 50), the level of creatinine (OR 4.6, 95 CI 1.1 to 10), and C-reactive protein (OR 3.2, 95% CI 0.9 to 15).
Sabaliauskene
Z
Z
Gaĭgaĭlaĭte
V
V
D000368:Aged; D001161:Arteriosclerosis / Q000097:blood* / Q000150:complications; D002097:C-Reactive Protein / Q000032:analysis; D017536:Carotid Artery, Common; D016893:Carotid Stenosis / Q000097:blood* / Q000150:complications; D003404:Creatinine / Q000097:blood; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D006710:Homocysteine; D002097:C-Reactive Protein; D003404:Creatinine