title: Iridoid glycosides from Harpagophytum procumbens D.C. (devil's claw).
abstract: Iridoid glycosides, harprocumbide A (6''-O-alpha-D-galactopyranosylharpagoside, 1) and harprocumbide B (6''-O-(cis-p-coumaroyl)-procumbide, 2) were isolated from the tubers of Harpagophytum prucumbens D.C., along with nine known iridoid glycosides 6-O-alpha-D-galactopyranosylharpagoside (3), and harpagoside (4), harpagide (5), 8-cinnamoylmyoporoside (6), 8-O-feruloylhapagide (7), procumbide (8), 6''-O-(p-coumaroyl)-procumbide (9), 8-O-(p-coumaroyl)-harpagide (10) and 8-O-(cis-p-coumaroyl)-harpagide (11). Compound 10 showed marginal inhibition activity against macrophages respiratory burst.
authors.affiliation: Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing 210009, PR China.
authors.forename: Jin
authors.initials: J
authors.lastname: Qi
authors.forename: Ji-Jun
authors.initials: JJ
authors.lastname: Chen
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Cheng
authors.forename: Jia-Hong
authors.initials: JH
authors.lastname: Zhou
authors.forename: Bo-Yang
authors.initials: BY
authors.lastname: Yu
authors.forename: Samuel X
authors.initials: SX
authors.lastname: Qiu
mesh_terms: D000818:Animals; D002460:Cell Line; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031684:Harpagophytum / Q000737:chemistry*; D039823:Iridoids / Q000737:chemistry*; D008264:Macrophages / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure
chemical_list: D006027:Glycosides; D039823:Iridoids