CoBr2(Bpy): an efficient catalyst for the direct conjugate addition of aryl halides or triflates onto activated olefins.
An efficient cobalt-catalyzed method devoted to the direct conjugate addition of functionalized aryl compounds onto Michael acceptors is described. The CoBr2(2,2'-bipyridine) complex appears to be an extremely suitable catalyst for the activation of a variety of aromatic reagents ranging from halides to triflates functionalized by reactive groups. This procedure allows for the synthesis of compounds resulting from 1,4-addition in good to excellent yields. The versatility of this original process represents a simple alternative to most known methods using organometallic reagents.
Amatore
Muriel
M
Laboratoire d'Electrochimie, Catalyse et Synthèse Organique, UMR 7582, Université Paris 12-C.N.R.S. 2, rue Henri Dunant, 94320 Thiais, France.
Gosmini
Corinne
C
Périchon
Jacques
J