title: The correlations between Central Corneal Thickness and age, gender, intraocular pressure and refractive error of aged 12-60 years old in rural Thai community.
abstract: OBJECTIVE
  To study the normal Central Corneal Thickness (CCT) and investigate the correlation between CCT and age, gender intraocular pressure and refractive error
  
  
  METHODS
  Population of age 12-60 years old were interviewed with standard questionnaire. Refractive error was measured and graded according to spherical equivalent power. Then intraocular pressure and central cornea thickness were measured by applanation tonometer and ultrasonic pachymeter, respectively. The data were analyzed using T-test, correlation and multivariate linear regression to identify mean CCT and correlation between age, gender, intraocular pressure, and refractive error.
  
  
  RESULTS
  A total of 467 participants were enrolled into the study. One hundred and eighty-six (39.8%) were males and 281 (60.2%) were females. The average CCT was 535.2 +/- 29.9 microm. The mean CCT of right and left eyes were 535.3 +/- 30.4 microm, and 535.1 +/- 29.5 microm, respectively. The multivariate linear regression indicated that increasing in age would decrease the CCT 0.28 microm and an increasing of intraocular pressure would increase the CCT 1.4 microm statistically significance.
  
  
  CONCLUSIONS
  The CCT was independently related to the refractive error and gender Greater CCT was associated with higher intraocular pressure. Conversely, thinner cornea was correlated with older age group.
authors.affiliation: Department of Ophthalmology, Phramongkutklao Hospital, Bangkok Thailand. Lek_mana@hotmail.com
authors.forename: Manapon
authors.initials: M
authors.lastname: Lekskul
authors.forename: Pote
authors.initials: P
authors.lastname: Aimpun
authors.forename: Bandit
authors.initials: B
authors.lastname: Nawanopparatskul
authors.forename: Saran
authors.initials: S
authors.lastname: Bumrungsawat
authors.forename: Thosapon
authors.initials: T
authors.lastname: Trakulmungkijkarn
authors.forename: Jiradech
authors.initials: J
authors.lastname: Charoenvanichvisit
authors.forename: Thanun
authors.initials: T
authors.lastname: Herunpattarawong
authors.forename: Panthep
authors.initials: P
authors.lastname: Suksangthong
authors.forename: Teerapat
authors.initials: T
authors.lastname: Jaiprasat
authors.forename: Monsit
authors.initials: M
authors.lastname: Rattananantapat
authors.forename: Trin
authors.initials: T
authors.lastname: Sudprasert
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003315:Cornea / Q000473:pathology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012030:Refractive Errors / Q000473:pathology*; D012423:Rural Health; D012737:Sex Factors; D013785:Thailand