title: Adherence to clinical guidance in the prescribing of oral antithrombotic medication in patients with atrial fibrillation.
abstract: BACKGROUND
  Atrial fibrillation is the commonest cardiac rhythm disturbance and is an independent risk factor for stroke; however, use of oral antithrombotic therapy is reported to be suboptimal in clinical practice.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the prescribing rates of oral antithrombotic therapy in patients with atrial fibrillation to determine if prescribing patterns reflected published clinical guidance.
  
  
  METHODS
  Patients with atrial fibrillation, admitted to hospital over a 12-week period were identified and their antithrombotic therapy regimen was analysed using statistical methods.
  
  
  RESULTS
  Although 87/100 patients identified were prescribed OAT, the regimen was suboptimal in 35 patients. Patients aged 75 years and older were more likelyto be receiving suboptimal oral antithrombotic treatment compared with younger patients
  
  
  CONCLUSIONS
  The benefits and suitability of oral antithrombotic therapy for patients of all ages need to be more comprehensively communicated to prescribers.
authors.affiliation: Dept of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St James's Hospital, Dublin.
authors.forename: M
authors.initials: M
authors.lastname: Savage
authors.forename: M
authors.initials: M
authors.lastname: Teeling
authors.forename: K
authors.initials: K
authors.lastname: Bennett
authors.forename: J
authors.initials: J
authors.lastname: Feely
mesh_terms: D000368:Aged; D000465:Algorithms; D001281:Atrial Fibrillation / Q000188:drug therapy*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D019983:Guideline Adherence; D006801:Humans; D007494:Ireland; D008297:Male; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012307:Risk Factors; D020521:Stroke / Q000517:prevention & control
chemical_list: D005343:Fibrinolytic Agents