title: The association of venous developmental anomalies and cavernous malformations: pathophysiological, diagnostic, and surgical considerations.
abstract: Developmental venous anomalies (DVAs) are often associated with intracranial cavernous malformations (CMs). The frequency of this association and the observation of de novo CMs located near a known, preexisting DVA raise speculations as to the possible etiopathogenetic relationship between the two. In this article, the authors review the recent literature dealing with the potential etiopathogenetic, prognostic, and therapeutic implications of the association between DVAs and CMs.
authors.affiliation: Neurosurgical Department, University of Florence, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Perrini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lanzino
mesh_terms: D001932:Brain Neoplasms / Q000209:etiology* / Q000503:physiopathology* / Q000601:surgery; D020787:Central Nervous System Venous Angioma / Q000209:etiology* / Q000503:physiopathology* / Q000601:surgery; D002550:Cerebral Veins / Q000002:abnormalities* / Q000473:pathology / Q000503:physiopathology; D003937:Diagnosis, Differential; D020786:Hemangioma, Cavernous, Central Nervous System / Q000209:etiology* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000503:physiopathology; D019635:Neurosurgical Procedures / Q000379:methods / Q000592:standards / Q000639:trends; D010641:Phenotype; D014656:Vascular Surgical Procedures / Q000379:methods / Q000592:standards / Q000639:trends