title: Use of nonsteroidal anti-inflammatory drugs and risk of oral cancer: a cohort study.
abstract: Epidemiologic data regarding the chemopreventive potential of nonsteroidal anti-inflammatory drugs (NSAIDs) against oral cancer are sparse. We found a relative risk for oral cancer of 1.2 (95% CI, 1.0-1.6) among 169,589 Danish NSAID users (> or =2 prescriptions), with no apparent trends in subgroups. Our study provided no clear evidence that NSAIDs may protect against oral cancer.
authors.affiliation: Institute of Cancer Epidemiology, Department of Genetics and Medicine, Danish Cancer Society, DK-2100 Copenhagen, Denmark. friis@cancer.dk
authors.forename: S
authors.initials: S
authors.lastname: Friis
authors.forename: A
authors.initials: A
authors.lastname: Poulsen
authors.forename: L
authors.initials: L
authors.lastname: Pedersen
authors.forename: J A
authors.initials: JA
authors.lastname: Baron
authors.forename: H T
authors.initials: HT
authors.lastname: Sørensen
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000367:Age Factors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D005500:Follow-Up Studies; D005783:Gender Identity; D006801:Humans; D015994:Incidence; D009062:Mouth Neoplasms / Q000453:epidemiology* / Q000517:prevention & control; D012042:Registries; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal