title: Perforation of the colon: a rare complication of hepatocellular carcinoma.
abstract: Direct infiltration of the colon by hepatocellular carcinoma (HCC) is a rare condition. Only a few reports can be found in the literature. Here we present a case of direct infiltration of the ascending colon by an exophytic growing HCC of the right posterior liver lobe, in which treatment with transarterial chemoembolization (TACE) had been performed. Tumor invasion became evident by abdominal pain and lower gastrointestinal bleeding. Diagnosis was established by contrast-enhanced multidetector computed tomography (CE-MDCT), demonstrating the direct tumor invasion with concomitant perforation of the infiltrated colon segment. Based on these findings, rapid and effective surgical treatment could be achieved.
authors.affiliation: Institute of Clinical Radiology, Department of Gastroenterology, Munich University Hospitals - Grosshadern, Munich, Germany. Christoph.Zech@med.uni-muenchen.de
authors.forename: C J
authors.initials: CJ
authors.lastname: Zech
authors.forename: M
authors.initials: M
authors.lastname: Bilzer
authors.forename: U G
authors.initials: UG
authors.lastname: Mueller-Lisse
authors.forename: H O
authors.initials: HO
authors.lastname: Steitz
authors.forename: S
authors.initials: S
authors.lastname: Haraida
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D044682:Colon, Ascending / Q000473:pathology*; D003108:Colonic Diseases / Q000209:etiology*; D003287:Contrast Media; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007416:Intestinal Perforation / Q000209:etiology*; D008113:Liver Neoplasms / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media