title: Degenerative lumbar scoliosis.
abstract: In adults, symptomatic scoliosis is usually a de novo primary degenerative deformity that develops in the fifth or sixth decade or an unrecognized or untreated idiopathic deformity with superimposed degeneration. The evaluation and treatment of adult scoliosis must focus on addressing patient symptoms while limiting the consequences of the treatment. The presence of neurological deficits, the flexibility of the deformity, the coronal and sagittal balance, and status of spinal segments outside of the main deformity are all important considerations when planning surgery. The complication rate of deformity surgery in adults is potentially high; but excellent functional outcome and patient satisfaction can occur with thorough preoperative patient education and meticulous surgical technique.
authors.affiliation: Department of Neurological Surgery, University of Virginia, PO Box 800212, Charlottesville, VA 22902, USA.
authors.forename: Rod J
authors.initials: RJ
authors.lastname: Oskouian
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Shaffrey
mesh_terms: D000328:Adult; D001685:Biological Factors / Q000627:therapeutic use; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use; D006801:Humans; D016268:Internal Fixators; D007403:Intervertebral Disc; D008159:Lumbar Vertebrae; D019637:Orthopedic Procedures / Q000009:adverse effects / Q000379:methods*; D012600:Scoliosis / Q000145:classification / Q000209:etiology / Q000601:surgery*; D016212:Transforming Growth Factor beta / Q000627:therapeutic use
chemical_list: C525718:BMP2 protein, human; D001685:Biological Factors; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta