The freshwater invertebrate Mysis relicta can eliminate chiral organochlorine compounds enantioselectively.
Accumulation and elimination of chiral polychlorinated biphenyls (PCBs) and organochlorine (OC) pesticides by the opossum shrimp, Mysis relicta, was investigated to determine if zooplankton can stereoselectively process chiral OC contaminants. Concentrations and enantiomer fractions were measured within mysids over a 10-day exposure followed by a 45-day depuration period. Rapid accumulation occurred within mysids exposed to sediment contaminated with racemic chiral OC compounds at microg/g levels. Enantiomer enrichment was observed within mysids for the second-eluting enantiomer and the (-)-enantiomer of PCB 95 and trans-chlordane, respectively, after 7 days of exposure to spiked sediment, and for the second-eluting enantiomers of PCBs 91 and 183 and (-)-PCB 149 over longer time periods. Enantiomer fractions decreased with time during the depuration phase of the experiment for these compounds, showing that their elimination from mysids was stereoselective. Oxychlordane was detected in nonracemic proportions after exposure, indicating that mysids can metabolize trans-chlordane enantioselectively. Minimum elimination rates calculated were higher than biotransformation rates calculated for fish in previous studies, which have been shown to metabolize OC contaminants. This study is the first to show stereoselective processing of chiral OC contaminants by aquatic invertebrates.
Warner
Nicholas A
NA
Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2 Canada.
Wong
Charles S
CS
D000818:Animals; D003445:Crustacea / Q000378:metabolism*; D005618:Fresh Water / Q000737:chemistry*; D019015:Geologic Sediments / Q000737:chemistry; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry / Q000378:metabolism*; D008968:Molecular Conformation; D010575:Pesticides / Q000737:chemistry / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000737:chemistry / Q000378:metabolism; D013237:Stereoisomerism; D014874:Water Pollutants, Chemical / Q000378:metabolism*; D015048:Zooplankton / Q000378:metabolism
D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls