title: Metastatic squamous cell carcinoma in a cat.
abstract: A 7-year-old, spayed female Persian cat was referred for evaluation of progressive paraplegia. The cat was thin, cachectic and paraplegic on presentation. The survey radiographs showed a left caudal pulmonary lesion and lytic skeletal lesions at the right iliac crest and left distal scapula. Due to a poor prognosis for complete recovery, the owner opted for euthanasia. Post-mortem examination revealed bilaterally small and irregular kidneys, lysis of the left iliac crest and left distal scapula and a dilated left ventricular lumen with a thin interventricular septum. Histologically, all the lesions were determined to be squamous cell carcinoma. It appears that the origin or the primary site of the malignancy in this case is pulmonary as cardiac and skeletal tissues are primarily mesenchymal in origin and are less likely to develop a primary epithelial malignancy. To the best of our knowledge, there is no description of cardiac or skeletal metastatic squamous cell carcinoma in a cat.
authors.affiliation: All Care Animal Referral Center, 18440 Amistad Street, Fountain Valley, CA 92708, USA. ravidvm@sbcglobal.net <ravidvm@sbcglobal.net>
authors.forename: Ravinder S
authors.initials: RS
authors.lastname: Dhaliwal
authors.forename: Eric
authors.initials: E
authors.lastname: Kufuor-Mensah
mesh_terms: D000818:Animals; D001344:Autopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary* / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D003937:Diagnosis, Differential; D005260:Female; D006338:Heart Neoplasms / Q000662:veterinary; D008175:Lung Neoplasms / Q000662:veterinary; D010264:Paraplegia / Q000662:veterinary