The application of microarray analysis to pediatric diseases.
DNA microarrays are a tool for simultaneously assessing the expression levels of thousands of genes in a single experiment, making them well-suited to understanding the complex gene response patterns and the regulatory pathways involved in human disease. This article reviews the basics of array technology and analysis, and highlights its application to pediatric diseases.
Hessner
Martin J
MJ
The Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. mhessner@mcw.edu
Liang
Mingyu
M
Kwitek
Anne E
AE
D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000235:genetics; D002648:Child; D006402:Hematologic Diseases / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008659:Metabolic Diseases / Q000175:diagnosis* / Q000235:genetics; D046228:Microarray Analysis; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics; D010372:Pediatrics / Q000379:methods