title: Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.
authors.affiliation: Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8N 3Z5, Canada.
authors.forename: Nadine H
authors.initials: NH
authors.lastname: Elowe
authors.forename: Razvan
authors.initials: R
authors.lastname: Nutiu
authors.forename: Abdellah
authors.initials: A
authors.lastname: Allali-Hassani
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Cechetto
authors.forename: Donald W
authors.initials: DW
authors.lastname: Hughes
authors.forename: Yingfu
authors.initials: Y
authors.lastname: Li
authors.forename: Eric D
authors.initials: ED
authors.lastname: Brown
mesh_terms: D000243:Adenosine Deaminase / Q000737:chemistry; D058892:Adenosine Deaminase Inhibitors; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001665:Binding Sites; D015374:Biosensing Techniques / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D019793:Fluorescein / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D058892:Adenosine Deaminase Inhibitors; D052157:Aptamers, Nucleotide; D004791:Enzyme Inhibitors; D005456:Fluorescent Dyes; D000243:Adenosine Deaminase; D019793:Fluorescein