Recurrent respiratory papillomatosis.
Recurrent respiratory papillomatosis (RRP) is a benign, often multi-focal neoplasm. A potentially fatal manifestation of human papilloma virus infection, the condition is characterised by multiple warty excrescences on the mucosal surface of the respiratory tract. RRP is rare--incidence is estimated at 3.5 per million person-years, with a prevalence of 4 in 100,000 children. Affected children usually require multiple interventions; the impact on patients, their families, and the healthcare system is considerable. Treatment of RRP accounts for an estimated dollar 109 million annual expenditure in the USA.
Tasca
R A
RA
Leighton Hospital, Crewe, UK. r.tasca@btinternet.com
Clarke
R W
RW
D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D042241:Early Diagnosis; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000628:therapy; D010212:Papilloma / Q000175:diagnosis / Q000628:therapy; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000628:therapy; D012142:Respiratory Tract Neoplasms / Q000175:diagnosis / Q000628:therapy; D014140:Tracheotomy / Q000379:methods
D000998:Antiviral Agents