title: 3D dynamical ultrasonic model of pulsating vessel walls.
abstract: The aim of this work is to introduce a novel 3-D model of pulsating vessels, through which the dynamic acoustic response of arterial regions can be predicted. Blood flow is numerically simulated by considering the fluid-dynamic displacements of the scatterers (erythrocytes), while a mechanical model calculates the wall displacement due to fluid pressure. The acoustic characteristics of each region are simulated through the FIELD software. Two numerical phantoms of a carotid artery surrounded by elastic tissue have been developed to illustrate the model. One of them includes a plaque involving a 50% stenosis. B-mode and M-mode images are produced and segmented to obtain the wall displacement profile. A cylindrical holed phantom made of cryogel mimicking material has been constructed for the model validation. In pulsatile flow conditions, fluid and wall displacements have been measured by Doppler ultrasound methods and quantitatively compared to simulated M-mode images, showing a fairly good agreement.
authors.affiliation: CREATIS, Université Claude Bernard Lyon 1, CNRS UMR 5515, INSERM U630, Lyon, France. balocco@creatis.insa-lyon.fr <balocco@creatis.insa-lyon.fr>
authors.forename: S
authors.initials: S
authors.lastname: Balocco
authors.forename: O
authors.initials: O
authors.lastname: Basset
authors.forename: G
authors.initials: G
authors.lastname: Courbebaisse
authors.forename: P
authors.initials: P
authors.lastname: Delachartre
authors.forename: P
authors.initials: P
authors.lastname: Tortoli
authors.forename: C
authors.initials: C
authors.lastname: Cachard
mesh_terms: D001158:Arteries / Q000000981:diagnostic imaging* / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D003198:Computer Simulation; D004548:Elasticity; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D011673:Pulsatile Flow / Q000502:physiology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D033081:Shear Strength; D013314:Stress, Mechanical; D014463:Ultrasonography / Q000379:methods*