title: Increase in catheter insertion-site infections associated to the introduction of a substandard competitive antiseptic.
abstract: The introduction of low-cost competitive antiseptic products may offer savings, but, unfortunately, their quality control is poor in many developing countries. The use of a new brand of idopovidone solution, used routinely for catheter insertion-site cleaning, was associated with a 55% increase in catheter insertion-site infection per 100 active catheters, returning to usual after the product was recalled. The new brand of iodopovidone solution had less free iodine (.76%) and lower pH (2.7) than required by local standards (pH 3-6.5). Use of substandard antiseptics in developing countries, because of poor quality control, is a risk for patients and results in increased health services expenses and burden of work.
authors.affiliation: Instituto Nacional de Cancerología, México City, Mexico. volkow@perezpadilla-volkow.com.mx
authors.forename: Patricia
authors.initials: P
authors.lastname: Volkow
authors.forename: Silvia
authors.initials: S
authors.lastname: Sandoval
authors.forename: Angeles Martinéz
authors.initials: AM
authors.lastname: Campos
authors.forename: Margarita
authors.initials: M
authors.lastname: Gutiérrez
authors.forename: Cecilia
authors.initials: C
authors.lastname: de Romero
authors.forename: José Joaquín
authors.initials: JJ
authors.lastname: Viana Aguiluz
authors.forename: Jose Rogelio
authors.initials: JR
authors.lastname: Perez Padilla
mesh_terms: D000891:Anti-Infective Agents, Local / Q000592:standards; D002408:Catheters, Indwelling / Q000009:adverse effects* / Q000382:microbiology; D015331:Cohort Studies; D003428:Cross Infection / Q000209:etiology*; D006801:Humans; D017053:Infection Control / Q000379:methods; D011206:Povidone-Iodine / Q000592:standards
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine