title: Treating itch in psoriasis.
abstract: Itch is an important, but underestimated symptom in psoriasis. Many therapies are available for pruritus; however, few are effective for psoriatic itch. Antipruritic therapies that are potentially effective in psoriasis include coal tar products, topical corticosteroids, topical salicylates, menthol and pramoxine, capsaicin, phototherapy, vitamin D analogs, topical immunomodulators, methotrexate, oral mirtazapine, and biologics. Using these therapies can benefit psoriasis patients in the outpatient clinical setting.
authors.affiliation: Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
authors.forename: Aerlyn
authors.initials: A
authors.lastname: Dawn
authors.forename: Gil
authors.initials: G
authors.lastname: Yosipovitch
mesh_terms: D000279:Administration, Cutaneous; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000982:Antipruritics / Q000627:therapeutic use; D002211:Capsaicin / Q000627:therapeutic use; D003033:Coal Tar / Q000627:therapeutic use; D004643:Emollients / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007641:Keratolytic Agents / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D008803:Mianserin / Q000031:analogs & derivatives / Q000627:therapeutic use; D000078785:Mirtazapine; D009025:Morpholines / Q000627:therapeutic use; D010789:Phototherapy; D011537:Pruritus / Q000209:etiology* / Q000523:psychology / Q000628:therapy*; D011565:Psoriasis / Q000150:complications*; D011788:Quality of Life; D012459:Salicylates / Q000627:therapeutic use; D017592:Skin Care / Q000379:methods; D014807:Vitamin D / Q000031:analogs & derivatives
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000982:Antipruritics; D004643:Emollients; D006634:Histamine H1 Antagonists; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D007641:Keratolytic Agents; D009025:Morpholines; D012459:Salicylates; C005548:pramoxine; D014807:Vitamin D; D008803:Mianserin; D003033:Coal Tar; D000078785:Mirtazapine; D002211:Capsaicin; D008727:Methotrexate