Phosphazene base-catalyzed condensation of trimethylsilylacetate with carbonyl compounds.
The t-Bu-P4 base was found to be an excellent catalyst for the condensation of trimethylsilylacetate or trimethylacetonitrile with carbonyl compounds to form functionalized alkenes and beta-enaminoesters were also synthesized by the condensation with formanilides.
Kobayashi
Koji
K
Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki Aza Aoba 6-3, Sendai, 980-8578, Japan.
Ueno
Masahiro
M
Kondo
Yoshinori
Y
D000097:Acetonitriles / Q000737:chemistry; D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D005559:Formamides / Q000737:chemistry; D017646:Organosilicon Compounds / Q000737:chemistry*; D010753:Phosphoranes / Q000494:pharmacology*
D000097:Acetonitriles; D000475:Alkenes; D004952:Esters; D005559:Formamides; D017646:Organosilicon Compounds; C510992:P1-tBU phosphazene; D010753:Phosphoranes; C045976:N-phenylformamide; D002244:Carbon; C032159:acetonitrile