[Chemoembolization of bilateral internal iliac arteries in Miles operation].
OBJECTIVE
To prospectively investigate the efficacy of chemoembolization of bilateral internal iliac arteries in patients underwent Miles operation.


METHODS
One hundred and thirteen patients with rectal cancer were randomly classified into 2 groups. The chemoembolization of bilateral internal iliac arteries with anticancer agents and gelatin sponge particles was applied during Miles operation in the treatment group (68 cases), while Miles operation was performed in the control group (45 cases). The amount of intraoperative bleeding, the operation time, the incidence of local recurrence, and the 5 year survival rate were analyzed and compared between the 2 groups.


RESULTS
The complications and the operation time had not significantly different in both groups (P > 0. 05); the amount of bleeding and the incidence of local pelvic recurrence were less, and the 5 year survival rate was higher in the treatment group than that in the control group (P <0.05).


CONCLUSIONS
In Miles operation of rectal cancer, the chemoembolization of bilateral internal iliac arteries is a safe and effective therapy, and it can improve the efficacy of rectal cancer both in the short and long run.
Hao
Sheng-hua
SH
Department of Surgery, Third Xiangya Hospital, Central South University, Changsha, China. haoshx31@yahoo.com.cn
Liu
Fei-long
FL
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016461:Chemoembolization, Therapeutic; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007083:Iliac Artery; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D015996:Survival Rate
D016685:Mitomycin; D005472:Fluorouracil