Signalling from parathyroid hormone.
PTH (parathyroid hormone), acting via type 1 PTH receptors, is a major regulator of plasma [Ca(2+)]. The G-protein, G(s), is an essential component of the sequence linking PTH to plasma Ca(2+) regulation, but the relative importance of intracellular signals, including Ca(2+) and cAMP, that lie downstream of G(s) is not resolved.
Tovey
S C
SC
Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
Dedos
S G
SG
Taylor
C W
CW
D000818:Animals; D002118:Calcium / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D010281:Parathyroid Hormone / Q000378:metabolism*; D018016:Receptors, Parathyroid Hormone / Q000378:metabolism; D015398:Signal Transduction
D010281:Parathyroid Hormone; D018016:Receptors, Parathyroid Hormone; D019204:GTP-Binding Proteins; D002118:Calcium