title: Combined IV-intra-arterial thrombolysis: a color-coded duplex pilot study.
abstract: The authors compared the transcranial color-coded duplex pattern of the middle cerebral arteries (MCAs) before and after IV and combined IV-intra-arterial (IV-IA) thrombolysis in consecutive first-ever stroke patients. Patients receiving combined IV-IA thrombolysis showed greater improvement in flow signal and higher incidence of complete MCA recanalization vs those receiving IV thrombolysis, especially when the MCA was occluded or had only minimal flow.
authors.affiliation: Department of Neurology, University Hospital and Medical School of Geneva, Geneva, Switzerland. fabienne.perren@hcuge.ch
authors.forename: F
authors.initials: F
authors.lastname: Perren
authors.forename: J
authors.initials: J
authors.lastname: Loulidi
authors.forename: R
authors.initials: R
authors.lastname: Graves
authors.forename: H
authors.initials: H
authors.lastname: Yilmaz
authors.forename: D
authors.initials: D
authors.lastname: Rüfenacht
authors.forename: T
authors.initials: T
authors.lastname: Landis
authors.forename: R
authors.initials: R
authors.lastname: Sztajzel
mesh_terms: D000368:Aged; D018618:Echocardiography, Doppler, Color / Q000379:methods*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D008297:Male; D010865:Pilot Projects; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents