title: [Megavoltage cone-beam CT: Recent developments and clinical applications].
abstract: The Megavoltage cone-beam (MV CBCT) system consists of a new a-Si flat panel adapted for MV imaging and an integrated workflow application allowing the automatic acquisition of projection images, cone-beam CT image reconstruction, CT to CBCT image registration and couch position adjustment. This provides a 3D patient anatomy volume in the actual treatment position, relative to the treatment isocenter, moments before the dose delivery, that can be tightly aligned to the planning CT, allowing verification and correction of the patient position, detection of anatomical changes and dose calculation. In this paper, we present the main advantages and performance of this MV CBCT system and summarize the different clinical applications. Examples of the image-guided treatment process from the acquisition of the MV CBCT scan to the correction of the couch position and dose delivery will be presented for spinal and lung lesions and for head and neck, and prostate cancers.
authors.affiliation: Department of radiation oncology, university of California San Francisco, comprehensive cancer center, 1600 Divisadero street, Suite H1031, San Francisco, CA-94143, USA. pouliot@radonc17.ucsf.edu
authors.forename: J
authors.initials: J
authors.lastname: Pouliot
authors.forename: O
authors.initials: O
authors.lastname: Morin
authors.forename: M
authors.initials: M
authors.lastname: Aubin
authors.forename: J-F
authors.initials: JF
authors.lastname: Aubry
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: Speight
authors.forename: M
authors.initials: M
authors.lastname: Roach
mesh_terms: D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006622:Hip Prosthesis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008175:Lung Neoplasms / Q000532:radiotherapy; D008297:Male; D011187:Posture; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D011881:Radiotherapy, Computer-Assisted; D013125:Spinal Neoplasms / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed / Q000379:methods*