Perioperative management of a heterozygous carrier of Glanzmann's thrombasthenia submitted to coronary artery bypass grafting with cardiopulmonary bypass.
Glanzmann's thrombasthenia is a congenital hemorrhagic disorder transmitted as an autosomal recessive trait and characterized by altered production and/or assembly of the platelet membrane glycoprotein IIb/IIIa receptor. We describe the perioperative management of a heterozygous carrier of Glanzmann's thrombasthenia submitted to cardiac surgery with cardiopulmonary bypass and the case was complicated by early excessive postoperative bleeding.
Casati
Valter
V
Division of Cardiovascular Anesthesia and Intensive Care, Policlinico di Monza, via Amati 111, Monza (20052), Italy. valter.casati@policlinicodimonza.it
D'Angelo
Armando
A
Barbato
Luciano
L
Rossi
Edoardo
E
Grasso
Maria Antonietta
MA
Spagnolo
Salvatore
S
Panzeri
Ezio
E
D000368:Aged; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D006579:Heterozygote; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000209:etiology; D013915:Thrombasthenia / Q000150:complications*; D014148:Tranexamic Acid / Q000627:therapeutic use
D014148:Tranexamic Acid