title: Pyridostigmine in autonomic failure: can we treat postural hypotension and bladder dysfunction with one drug?
abstract: In a 66-year-old man with autonomic failure, pyridostigmine (180 mg/day orally) improved both postural hypotension and underactive detrusor bladder dysfunction. Acetylcholinesterase inhibition may be useful in the management of orthostatic hypotension and bladder dysfunction in autonomic failure patients.
authors.affiliation: Dept. of Neurology, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670, Japan. tatsuya-yamamoto@mbc.nifty.com
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sakakibara
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Uchiyama
authors.forename: Masato
authors.initials: M
authors.lastname: Asahina
authors.forename: Zhi
authors.initials: Z
authors.lastname: Liu
authors.forename: Takashi
authors.initials: T
authors.lastname: Ito
authors.forename: Yu
authors.initials: Y
authors.lastname: Koyama
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Awa
authors.forename: Kaori
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Mika
authors.initials: M
authors.lastname: Kinou
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000188:drug therapy*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D011729:Pyridostigmine Bromide / Q000627:therapeutic use*; D001745:Urinary Bladder Diseases / Q000188:drug therapy* / Q000209:etiology
chemical_list: D002800:Cholinesterase Inhibitors; D011729:Pyridostigmine Bromide