Adsorptive stripping voltammetric assay of folic acid in human serum.
Folic acid was voltammetrically measured after preconcentration by adsorption at the static mercury drop electrode. Phase selective AC voltammetry provided the most sensitive stripping signal. After previous analyte extraction, using liquid-solid extraction with a C-18 reversed phase cartridge, the method was suitable for folic acid measurement in human serum. The detection limit was 5.9 x 10(-9) M with an overall precision of 9.9% (R.S.D.; n = 7) at the concentration level of 1.0 x 10(-7) M with a mean recovery of 57%.
Fernandez Alvarez
J M
JM
Departamento de Química Física y Analítica, Universidad de Oviedo, 33071 Oviedo, Asturias, Spain.
Costa Garcia
A
A
Miranda Ordieres
A J
AJ
Tunón Blanco
P
P