title: A route to regioselectively functionalized carbazoles, dibenzofurans, and dibenzothiophenes through anionic cyclization of benzyne-tethered aryllithiums.
abstract: The treatment of 2-fluorophenyl 2-iodophenylamines, ether, and thioether, easily prepared from commercially available products, with 3.3 equiv of t-BuLi and further reaction with selected electrophiles gives rise to functionalized carbazole, dibenzofuran, and dibenzothiophene derivatives in a direct and regioselective manner. The process involves an anionic cyclization on a benzyne-tethered aryllithium intermediate.
authors.affiliation: Departamento de Química, Area de Química Organica, Facultad de Ciencias, Universidad de Burgos, Pza. Misael Bañuelos s/n, 09001-Burgos, Spain. rsd@ubu.es
authors.forename: Roberto
authors.initials: R
authors.lastname: Sanz
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Fernandez
authors.forename: M Pilar
authors.initials: MP
authors.lastname: Castroviejo
authors.forename: Antonio
authors.initials: A
authors.lastname: Pérez
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Fañanas