title: Real-time quadrature projection complex conjugate resolved Fourier domain optical coherence tomography.
abstract: We present a novel algorithm for full-range imaging by suppression of the complex conjugate artifact in phase-shifting Fourier domain optical coherence tomography. This technique utilizes the projection of multiple phase-shifted interferograms onto an orthogonal basis set to reconstruct the complex interferogram. Full-range imaging with >30 dB suppression of the symmetric artifact is demonstrated using a 3 x 3 fiber coupler swept source OCT system, providing a depth range of 6.6mm with -8 dB roll-off in sensitivity at the depth boundaries relative to DC. Real-time display of full-range images of the anterior segment of the human eye acquired in vivo at a line rate of 6.67 kHz are presented.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. marunko.sarunic@duke.edu
authors.forename: Marinko V
authors.initials: MV
authors.lastname: Sarunic
authors.forename: Brian E
authors.initials: BE
authors.lastname: Applegate
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Izatt
mesh_terms: D000465:Algorithms; D003199:Computer Systems; D005583:Fourier Analysis; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D015203:Reproducibility of Results; D012160:Retina / Q000166:cytology; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*