Total synthesis of (-)-spongidepsin.
[structure: see text] A convergent and rapid stereoselective synthesis of (-)-spongidepsin has been achieved from the Roche ester in 14 steps with an overall yield of 13%.
Ferrié
Laurent
L
ESPCI, Laboratoire de Chimie Organique, 10 Rue Vauquelin, 75231 Paris Cedex 05, France.
Reymond
Sébastien
S
Capdevielle
Patrice
P
Cossy
Janine
J
D000818:Animals; D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry; D013237:Stereoisomerism
D047630:Depsipeptides; C498389:spongidepsin