title: Large mesenteric gastrointestinal stromal tumor in a patient with familial adenomatous polyposis syndrome.
abstract: We report a case of a 30-year-old man who presented with severe debilitation, anemia and diarrhea over two months. Colonoscopy revealed many (>100) polyps (familial adenomatous polyposis syndrome). Abdominal CT scan showed a large mass at the left upper abdomen in conjunction with the splenic flexure. Total colectomy with mesenteric mass and adjacent small bowel removal and ileoanal pouch was performed. Examination of the resected mesenteric mass showed a gastrointestinal stromal tumor (GIST) with scarce mitosis and infiltration of the adjacent small bowel. We describe for the first time in medical literature the coexistence of familial adenomatous polyposis syndrome and GIST in a 30-year-old man.
authors.affiliation: Department of Gastroenterology, Theagenion Hospital, Thessaloniki, Greece.
authors.forename: John
authors.initials: J
authors.lastname: Moschos
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Tzilves
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Paikos
authors.forename: Georgios
authors.initials: G
authors.lastname: Tagarakis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Pilpilidis
authors.forename: Zissis
authors.initials: Z
authors.lastname: Antonopoulos
authors.forename: Savvas
authors.initials: S
authors.lastname: Kadis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Katsos
authors.forename: Anestis
authors.initials: A
authors.lastname: Tarpagos
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000175:diagnosis*; D000328:Adult; D046152:Gastrointestinal Stromal Tumors / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008643:Mesentery / Q000473:pathology*; D035583:Rare Diseases / Q000175:diagnosis; D013577:Syndrome