title: MRI planimetry for diagnosis and follow-up of valve area in mitral stenosis treated with valvuloplasty.
abstract: OBJECTIVE
  We sought to determine whether noninvasive planimetry by magnetic resonance imaging (MRI) is suitably sensitive and reliable for visualizing the mitral valve area (MVA) and for detecting increases in the MVA after percutaneous balloon mitral valvuloplasty (PBMV).
  
  
  METHODS
  In 8 patients with mitral valve stenosis, planimetry of the MVA was performed before and after PBMV with a 1.5 T MR scanner using a breath-hold balanced gradient echo sequence (True FISP). The data was compared to the echocardiographically determined MVA (ECHO-MVA) as well as to the invasively calculated MVA by the Gorlin formula at catheterization (CATH-MVA).
  
  
  RESULTS
  PBMV was associated with an increase of 0.79 +/- 0.30 cm (2) in the MVA (Delta MRI-MVA). The correlation between Delta MRI-MVA and Delta CATH-MVA was 0.92 (p < 0.03) and that between Delta MRI-MVA and Delta ECHO-MVA was 0.90 (p < 0.04). The overall correlation between MRI-MVA and CATH-MVA was 0.95 (p < 0.0001) and that between MRI-MVA and ECHO-MVA was 0.98 (p < 0.0001). MRI-MVA slightly overestimated CATH-MVA by 8.0 % (1.64 +/- 0.45 vs. 1.51 +/- 0.49 cm (2), p < 0.01) and ECHO-MVA by 1.8 % (1.64 +/- 0.45 vs. 1.61 +/- 0.43 cm (2), n. s.).
  
  
  CONCLUSIONS
  Magnetic resonance planimetry of the mitral valve orifice is a sensitive and reliable method for the noninvasive quantification of mitral stenosis and visualization of small relative changes in the MVA. This new method is therefore capable of diagnosing as well as following the course of mitral stenosis. It must be taken into consideration that planimetry by MRI slightly overestimates the MVA as compared to cardiac catheterization.
authors.affiliation: Institut für Röntgendiagnostik, Universitätsklinikum Regensburg, Regensburg. behrus.djavidani@klinik.uni-regensburg.de
authors.forename: B
authors.initials: B
authors.lastname: Djavidani
authors.forename: K
authors.initials: K
authors.lastname: Debl
authors.forename: S
authors.initials: S
authors.lastname: Buchner
authors.forename: C
authors.initials: C
authors.lastname: Lipke
authors.forename: W
authors.initials: W
authors.lastname: Nitz
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
authors.forename: G
authors.initials: G
authors.lastname: Riegger
authors.forename: A
authors.initials: A
authors.lastname: Luchner
mesh_terms: D019412:Anatomy, Cross-Sectional / Q000379:methods*; D002404:Catheterization / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology*; D008946:Mitral Valve Stenosis / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome