Rhamnose and rhamnitol in dual sugar permeability tests.
Rhamnose is one of the sugars regularly used to conduct the dual sugar permeability test. For more than 30 years, it has been assumed that rhamnose is an inert sugar not metabolized by the human body and only fermented by some colonic bacteria into rhamnulose. While conducting an investigation on gut permeability in children undergoing cardiac surgery, increased concentrations of rhamnitol were found in the urine samples. The present report suggests that rhamnose is not an inert sugar and it is partially metabolized into rhamnitol by the human body.
Malagon
Ignacio
I
Department of Anaesthesia, Leiden University Medical Centre, The Netherlands. jmalagon@lumc.nl
Onkenhout
Willem
W
Klok
Margreet
M
van der Poel
Petrus F H
PF
Bovill
James G
JG
Hazekamp
Mark G
MG
D003938:Diagnostic Techniques, Digestive System; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000378:metabolism*; D010539:Permeability; D012210:Rhamnose / Q000031:analogs & derivatives / Q000378:metabolism* / Q000652:urine*
D012210:Rhamnose