[The part of the hormone-cyclase system in achieving the therapeutic effect of hydrochloric acid secretion inhibitors at the duodenal ulcer].
There was a study of changes in blood hormone levels (gastrin, insulin, cortisol) and cyclic nucleotides (cAMPh, cGMPh) in the treatment of 120 patients with duodenal ulcer with anti-secretion drugs of different mechanisms of action. Changes in hormone and cyclic nucleotide levels were discovered both directly after the administration of anti-secretion drugs and after a course of treatment with them. The data obtained increase the knowledge about the mechanisms of anti-secretion drugs action and their influence on the stomach secretion function at the duodenal ulcer.
Vahrushev
Ia M
IaM
Muravtseva
O V
OV
D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D006728:Hormones / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009712:Nucleotides, Cyclic / Q000097:blood*
D000897:Anti-Ulcer Agents; D006728:Hormones; D009712:Nucleotides, Cyclic