Laryngopharyngeal reflux finding scores correlate with gastroesophageal reflux disease and Helicobacter pylori expression.
CONCLUSIONS
The expression of Helicobacter pylori (HP) positivity and degree of gastroesophageal reflux disease (GERD) correlate with laryngopharyngeal reflux (LPR). HP positivity and degree of GERD were more adverse in patients with a reflux finding score (RFS) of 7 or more.


OBJECTIVE
We aimed to investigate the relationship between RFS and inflammation of the lower part of the esophagus as well as RFS and HP infection.


METHODS
Forty-five consecutive patients were analyzed prospectively. The degree of LPR was evaluated using the RFS method. The degree of GERD, lower esophageal mucosal inflammation, and antral HP positivity were evaluated using endoscopic surveys.


RESULTS
The mean RFS of the whole population was 11.5+/-4.4. The mean RFS of patients who had lower esophageal mucosal inflammation was 7+/-0.1, 8.1+/-1.3, 13.9+/-3.7, and 16.6+/-3.5, for grades A, B, C and D, respectively. The RFS of patients according to HP expression was as follows: 7.2+/-0.4, 9.3+/-3.07, 12.7+/-3.16, and 17.8+/-2.1, for normal (score 0), score I, score II, and score III, respectively.
Tezer
Mesut Sabri
MS
Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey. mtezer2000@yahoo.com
Kockar
M Cem
MC
Koçkar
Olga
O
Celik
Alper
A
D000293:Adolescent; D000328:Adult; D004941:Esophagitis / Q000382:microbiology / Q000473:pathology; D004945:Esophagoscopy; D005260:Female; D005764:Gastroesophageal Reflux / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007818:Laryngeal Diseases / Q000382:microbiology* / Q000473:pathology; D007820:Laryngeal Mucosa / Q000382:microbiology / Q000473:pathology; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000382:microbiology* / Q000473:pathology; D011446:Prospective Studies; D012720:Severity of Illness Index