title: [A case of gastric endocrine cell carcinoma with liver metastasis showing rapid growth during pregnancy and marked reduction by systemic chemotherapy after delivery].
abstract: A 28-year-old woman was given a diagnosis of gastric endocrine cell carcinoma with multiple liver metastases in 1997. Chemotherapy was administered for treatment after a distal gastrectomy and hepatic tumor resection, and she had shown no sign of relapse after 2002. In February 2004, she was in the third month of pregnancy, and experienced recurrent liver metastasis. Although the tumor grew rapidly from 3cm to 10cm during her pregnancy, its size was significantly reduced with systemic chemotherapy after delivery. This is a rare case in which a liver metastasis of a gastric endocrine cell carcinoma grew during the course of pregnancy.
authors.affiliation: Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki.
authors.forename: Akemi
authors.initials: A
authors.lastname: Shirado
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Uto
authors.forename: Kazunori
authors.initials: K
authors.lastname: Kusumoto
authors.forename: Joji
authors.initials: J
authors.lastname: Kurogi
authors.forename: Hidemori
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Satoru
authors.initials: S
authors.lastname: Hasuike
authors.forename: Kenji
authors.initials: K
authors.lastname: Nagata
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Hayashi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Iwamitsu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hori
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ibusuki
authors.forename: Akio
authors.initials: A
authors.lastname: Ido
authors.forename: Hirohito
authors.initials: H
authors.lastname: Tsubouchi
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D036861:Delivery, Obstetric; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006498:Hepatectomy; D006801:Humans; D007262:Infusions, Intravenous; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D002945:Cisplatin; D005472:Fluorouracil