Longitudinal fMRI study for locomotor recovery in patients with stroke.
The authors investigated bihemispheric motor network reorganization supporting locomotor recovery after stroke over time. They determined longitudinal changes in locomotor function and fMRI in 10 stroke patients at the subacute stage and the chronic stage. The results suggest that the bihemispheric reorganization mechanism underlying locomotor recovery evolved from the ipsilateral (contralesional) primary sensorimotor cortex (SM1) activation at the subacute stage to the contralateral (ipsilesional) SM1 activation at the chronic stage.
Kim
Y H
YH
Department of Physical Medicine and Rehabilitation, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
You
S H
SH
Kwon
Y H
YH
Hallett
M
M
Kim
J H
JH
Jang
S H
SH
D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods; D005260:Female; D020233:Gait Disorders, Neurologic / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function / Q000502:physiology; D020521:Stroke / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*