Physiological properties of conjugated linoleic acid and implications for human health.
Conjugated linoleic acid (CLA) refers to a mixture of positional and geometric dienoic isomers of linoleic acid found naturally in animal products of ruminant sources. Recent interest in CLA research stems from the well-documented anticarcinogenic, antiatherogenic, antidiabetic, and antiobesity properties of CLA in rodents. However, there has been very little published human research on CLA. This review discusses the physiologic properties of CLA and their potential implications for human health.
Badinga
Lokenga
L
Department of Animal Sciences, University of Florida, PO Box 110910, Gainesville, 32910-0910, USA. badinga@animal.ufl.edu
Greene
Elizabeth S
ES
D000818:Animals; D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D001823:Body Composition / Q000187:drug effects; D004195:Disease Models, Animal; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D007536:Isomerism; D044243:Linoleic Acids, Conjugated / Q000737:chemistry / Q000502:physiology / Q000627:therapeutic use; D050356:Lipid Metabolism / Q000187:drug effects
D019440:Anti-Obesity Agents; D016588:Anticarcinogenic Agents; D000960:Hypolipidemic Agents; D044243:Linoleic Acids, Conjugated