Influence of implant surface topography on early osseointegration: a histological study in human jaws.
The purpose of this study was to evaluate the influence of the oxidized surface on bone-to-implant contact (BIC%), the bone density in the threaded area (BA%), as well as the bone density outside the threaded area (BD%) in human jaws after 2 months of unloaded healing. Thirteen subjects (mean age 42.61 +/- 6.15 years) received two microimplants (2.5 mm diameter and 6 mm length) each, during conventional mandible or maxilla implant surgery. The microimplants with commercially pure titanium surfaces (machined) and oxidized surfaces served as the control and test surfaces, respectively. After 2 months, the microimplants and the surrounding tissue were removed and prepared for histomorphometric analysis. All microimplants, except two machined and one oxidized microimplant surfaces, were found to be clinically stable after the healing period. Histometric evaluation indicated that the mean BIC% was (21.71 +/- 13.11)% and (39.04 +/- 15.75)% for machined and oxidized microimplant surfaces, respectively. The BD% was higher for the oxidized surface, although there was no difference for maxilla and mandible. The oxidized surface impacted the BA% for the type-IV bone. Data suggest that the oxidized surface presented a higher bone-to-implant contact rate compared with machined surfaces under unloaded conditions, after a healing period of 2 months.
Shibli
Jamil Awad
JA
Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, Sao Paulo, Brazil. jshibli@ung.br
Grassi
Sauro
S
de Figueiredo
Luciene Cristina
LC
Feres
Magda
M
Marcantonio
Elcio
E
Iezzi
Giovanna
G
Piattelli
Adriano
A
D000328:Adult; D015519:Bone Density; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000033:anatomy & histology / Q000601:surgery; D008422:Materials Testing; D008437:Maxilla / Q000033:anatomy & histology / Q000601:surgery; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D016348:Osseointegration; D010084:Oxidation-Reduction; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium
D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium