title: Role for surgery as adjuvant therapy in optic nerve sheath meningioma.
abstract: OBJECTIVE
  To describe a role for optic nerve decompression as adjuvant surgical therapy in the management of optic nerve sheath meningioma in patients with severe, progressive visual loss and optic disc edema before or after radiation therapy.
  
  
  METHODS
  Interventional case report.
  
  
  RESULTS
  Two patients with unilateral optic nerve sheath meningioma had progressive visual loss (20/200 and no light perception) and disc edema. The first had previously undergone fractionated stereotactic radiotherapy and the second subsequently was treated with fractionated stereotactic radiotherapy after decompression surgery. After excision of a dural window and biopsy of the tumor from the nerve sheath, visual acuity improved to 20/25 and 20/200, respectively, both coinciding with resolution of disc edema.
  
  
  CONCLUSIONS
  In patients with optic nerve sheath meningioma with severe disc edema and rapid vision loss, surgery may serve an important but restricted, adjuvant role to radiation therapy under special conditions.
authors.affiliation: Institute of Ophthalmology and Visual Science, Department of Ophthalmology, UMDNJ - New Jersey Medical School, Newark, New Jersey 07103, USA. turbinre@umdnj.edu
authors.forename: Roger E
authors.initials: RE
authors.lastname: Turbin
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Wladis
authors.forename: Larry P
authors.initials: LP
authors.lastname: Frohman
authors.forename: Paul D
authors.initials: PD
authors.lastname: Langer
authors.forename: John S
authors.initials: JS
authors.lastname: Kennerdell
mesh_terms: D000328:Adult; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018317:Nerve Sheath Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D019574:Optic Nerve Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D010211:Papilledema / Q000175:diagnosis; D014786:Vision Disorders / Q000175:diagnosis