title: [Insulin therapy in patients with severe hypertriglyceridemia].
abstract: A series of seven patients with severe hypertriglyceridemia (triglyceride levels > 1000 mg/dL) is presented. Four of the patients were diabetics, two of them were in treatment with anti-retroviral drugs, and three of them presented acute pancreatitis. In all patients intravenous infusion of insulin was initiated at a rate of 0.05-2 U/kg/day. Two and a half days after this treatment, the serum triglyceride level remained lower than 400 mg/dL. There were no complications during the treatment. The long treatment included basal insulin, fibrates and avoidance of pharmacotherapy. Insulin therapy for diabetic and non-diabetic patients with severe hypertriglyceridemia is an effective and safe treatment.
authors.affiliation: Departamento de Endocrinología, Divisíon de Medicina Interna, Hospital de Especialidades 25, Instituto Mexicano del Seguor Social, Monterray, Nuevo Léon. hectoreloytamez@aol.com
authors.forename: Héctor Eloy
authors.initials: HE
authors.lastname: Tamez-Pérez
authors.forename: Ramón
authors.initials: R
authors.lastname: Sáenz-Gallegos
authors.forename: Karina
authors.initials: K
authors.lastname: Hernández-Rodríguez
authors.forename: Gerardo
authors.initials: G
authors.lastname: Forsbach-Sánchez
authors.forename: María Dolores
authors.initials: MD
authors.lastname: Gómez-de Ossio
authors.forename: Nancy
authors.initials: N
authors.lastname: Fernández-Garza
authors.forename: Eduardo
authors.initials: E
authors.lastname: Zapata-de la Garza
authors.forename: Alejandra Lorena
authors.initials: AL
authors.lastname: Tamez-Peña
mesh_terms: D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000188:drug therapy*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
chemical_list: D007328:Insulin