title: Clinician validation of Poison Control Center (PCC) intentional exposure cases involving prescription opioids.
abstract: Poison Control Center (PCC) cases involving intentional ingestion, injection or inhalation of prescription opioids are a potentially valuable source of information on the abuse and misuse of these products. This study sought to validate PCC classifications of prescription opioid intentional exposure cases against clinical diagnostic criteria. 4,321 cases were reviewed. PCC-clinician concordance was good to excellent for Withdrawal, Abuse, and Suicide (kappa statistics: 0.73, 0.53, 0.48, respectively), but poor for Misuse and Intentional Unknown (Specific motive not known). Interrater reliability among clinicians was good (weighted kappa range: 0.56-0.68). Results demonstrate the degree of compatibility between PCC and standard nosologic classifications.
authors.affiliation: Purdue Pharma L.P., Stamford, Connecticut 06901-3431, USA. meredith.smith@pharma.com
authors.forename: Meredith Y
authors.initials: MY
authors.lastname: Smith
authors.forename: Richard
authors.initials: R
authors.lastname: Dart
authors.forename: Alice
authors.initials: A
authors.lastname: Hughes
authors.forename: Anne
authors.initials: A
authors.lastname: Geller
authors.forename: Edward
authors.initials: E
authors.lastname: Senay
authors.forename: George
authors.initials: G
authors.lastname: Woody
authors.forename: Salvatore
authors.initials: S
authors.lastname: Colucci
mesh_terms: D004353:Drug Evaluation, Preclinical; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D006801:Humans; D033182:Intention; D009294:Narcotics / Q000009:adverse effects; D015588:Observer Variation; D011039:Poison Control Centers / Q000706:statistics & numerical data*; D013375:Substance Withdrawal Syndrome / Q000453:epidemiology / Q000209:etiology; D019966:Substance-Related Disorders / Q000453:epidemiology*; D013405:Suicide / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires
chemical_list: D009294:Narcotics