Gold-catalyzed highly efficient access to 3(2H)-furanones from 2-oxo-3-butynoates and related compounds.
[reaction: see text] The gold-catalyzed cyclization reactions of 2-oxo-3-butynoic esters or disubstituted-1,2-diones with a variety of nucleophiles are described, which offer an efficient and straightforward route to substituted 3(2H)-furanones under mild reaction conditions. The Au(III) catalysts are also highly effective in the hydration of these activated alkynes.
Liu
Yuanhong
Y
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, People's Republic of China. yhliu@mail.sioc.ac.cn
Liu
Meina
M
Guo
Shenghai
S
Tu
Huamin
H
Zhou
Yebing
Y
Gao
Hongjun
H