Metabolic syndrome and gender differences in postprandial lipaemia.
BACKGROUND
Postprandial hyperlipidaemia may be a predictor of vascular risk.


METHODS
We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).


METHODS
Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.


RESULTS
Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.


CONCLUSIONS
Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.
Kolovou
Genovefa D
GD
First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. genkolovou@nail.gr
Anagnostopoulou
Katherine K
KK
Pavlidis
Antonis N
AN
Salpea
Klelia D
KD
Iraklianou
Stella A
SA
Hoursalas
Ioannis S
IS
Mikhailidis
Dimitri P
DP
Cokkinos
Dennis V
DV
D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006115:Greece / Q000453:epidemiology; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications*; D008875:Middle Aged; D019518:Postprandial Period / Q000502:physiology*; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides