Highly stereoselective oxidative esterification of aldehydes with beta-dicarbonyl compounds.
Copper-catalyzed oxidative esterification of aldehydes with beta-dicarbonyl compounds was developed using tert-butyl hydroperoxide as an oxidant. In general, the enol esters were synthesized in good yields (up to 87%) and high stereoselectivity under the optimized reaction conditions.
Yoo
Woo-Jin
WJ
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6, Canada.
Li
Chao-Jun
CJ
D000085:Acetates / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry*; D004951:Esterification; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000085:Acetates; D000447:Aldehydes; C116609:3-hydroxybutanal