title: [Preventive surgical treatment of ulcer disease].
abstract: The state of gastric secretion in ulcer disease patients was investigated. Acidity was estimated by a computed analysis of 24 hour acidogastromonitoring with apparatus AG-24 MP "Gastroscan-24". The examination of 739 patients with chronic duodenal ulcers included 139 (18.8%) patients with exacerbation, 306 (41.1%) with bleeding, 185 (25%) after suturing the perforation, 59 (8%) with stenosis + 50 healthy subjects. A correlation was found between the efficiency of antisecretory drugs and "malignancy" of the course of ulcer disease. An aggressive type of the course of ulcer disease was determined in 178 patients with indications for operation, but the operations were not performed, in 102 out of them long-term results were followed up. The long-term results of operative treatment of uncomplicated ulcer were followed up in 181 (59%) patients.
authors.forename: S A
authors.initials: SA
authors.lastname: Afendulov
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Zhuravlev
authors.forename: A D
authors.initials: AD
authors.lastname: Smirnov
authors.forename: N A
authors.initials: NA
authors.lastname: Krasnolutskiĭ
mesh_terms: D001285:Atropine; D013505:Digestive System Surgical Procedures / Q000379:methods; D018450:Disease Progression; D001330:Electronic Data Processing; D006801:Humans; D018727:Muscarinic Antagonists; D010437:Peptic Ulcer / Q000503:physiopathology / Q000517:prevention & control* / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality; D011788:Quality of Life; D012720:Severity of Illness Index; D013270:Stomach / Q000503:physiopathology; D011795:Surveys and Questionnaires; D014629:Vagotomy, Proximal Gastric / Q000379:methods
chemical_list: D018727:Muscarinic Antagonists; D001285:Atropine