title: Restrictive mitral inflow pattern is a strong independent predictor of lack of viable myocardium after a first acute myocardial infarction.
abstract: In patients with acute myocardial infarction (AMI) a restrictive mitral inflow pattern successfully predicts clinical outcome. The impact of myocardial viability on the mitral inflow velocities, however, is unknown. One hundred and forty-one patients with a first AMI underwent two-dimensional, Doppler and dobutamine stress echocardiography (DSE). Patients were classified into two groups based on Doppler measurement of left ventricular filling: a restrictive group (18 patients), and a non-restrictive group (123 patients). In the non-restrictive group, myocardial viability at DSE was found in 56 patients, while in the restrictive group only three patients showed contractile reserve (46% vs. 16%, p<0.03). The multivariate logistic regression analysis demonstrated that restrictive mitral inflow pattern was a strong independent predictor of lack of viable myocardium (OR=12.45, p<0.001).
authors.affiliation: Division of Cardiology, Santo Spirito Hospital, Lungotevere in Sassia 1, Rome, Italy. sestil@libero.it
authors.forename: Augusto
authors.initials: A
authors.lastname: Sestili
authors.forename: Claudio
authors.initials: C
authors.lastname: Coletta
authors.forename: Valerio
authors.initials: V
authors.lastname: Manno
authors.forename: Silvia
authors.initials: S
authors.lastname: Perna
authors.forename: Marco
authors.initials: M
authors.lastname: Renzi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Romano
authors.forename: Roberto
authors.initials: R
authors.lastname: Ricci
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ceci
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D016009:Chi-Square Distribution; D004280:Dobutamine; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011379:Prognosis; D012680:Sensitivity and Specificity
chemical_list: D004280:Dobutamine