Right-sided cardiac involvement in osteogenesis imperfecta.
Skeletal manifestations are the hallmark of the osteogenesis imperfecta group of disorders. Extraskeletal involvement may, however, contribute significantly to morbidity. Structural cardiovascular anomalies reported in osteogenesis imperfecta include aortic root dilatation and aortic and mitral valve dysfunction. Herein is reported the first case of involvement of the right side of the heart in osteogenesis imperfecta.
Khashu
Minesh
M
Neonatal Service, University Hospitals of Leicester, UK. mineshkhashu@gmail.com
Pelligra
Gustavo
G
Sandor
George G S
GG
Singh
Avash J
AJ
D045462:Endothelium-Dependent Relaxing Factors / Q000008:administration & dosage; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000503:physiopathology; D017380:Hypertrophy, Right Ventricular / Q000000981:diagnostic imaging / Q000473:pathology; D007231:Infant, Newborn; D007902:Length of Stay; D009569:Nitric Oxide / Q000008:administration & dosage; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000175:diagnosis; D010351:Patient Discharge; D010879:Piperazines / Q000008:administration & dosage; D011687:Purines; D013902:Radiography, Thoracic; D000068677:Sildenafil Citrate; D013450:Sulfones; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000002:abnormalities / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014665:Vasodilator Agents / Q000008:administration & dosage
D045462:Endothelium-Dependent Relaxing Factors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D009569:Nitric Oxide; D000068677:Sildenafil Citrate