title: [Successful treatment with oral tacrolimus in a case of severe ulcerative colitis complicated with primary diabetes mellitus].
abstract: We report a case of severe ulcerative colitis complicated with primary diabetes mellitus that was effectively treated with oral tacrolimus. A 36-year-old man suffered his first attack of ulcerative colitis. Because it was difficult to control the patient's diabetes, we instituted tacrolimus and azathioprine without a corticosteroid regimen as the initial treatment. Within two weeks, the ulcerative colitis activity went into remission and the patient's diabetes did not worsen.
authors.affiliation: Department of Gastroenterology, Fukuoka University Chikushi Hospital.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yano
authors.forename: Fumihito
authors.initials: F
authors.lastname: Hirai
authors.forename: Yoko
authors.initials: Y
authors.lastname: Wada
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Matsui
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus