title: [Pathophysiology of irritable bowel syndrome].
abstract: Irritable bowel syndrome (IBS) is considered a biopsychosocial disorder resulting from a combination of 3 interacting mechanisms: psychosocial factors, altered motility and transit, which may reflect severity of bowel dysfunction, and increased sensitivity of the intestine or colon. In other words, mechanism in IBS is biopsychosocial disorders; psychosocial factors, altered motility, and heightened sensory function. Understanding the brain-gut axis is the key to the eventual development of effective therapies for IBS.
authors.affiliation: Department of Internal Medicine, The Jikei University School of Medicine.
authors.forename: Akira
authors.initials: A
authors.lastname: Torii
mesh_terms: D001921:Brain / Q000502:physiology; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000503:physiopathology*; D011584:Psychology