Aminothiazole derivatives as neuropeptide Y5 receptor ligands: finding the balance between affinity and physicochemical properties.
Nettekoven
Matthias
M
F. Hoffmann-La Roche Ltd., Pharmaceutical Research Basel, Discovery Chemistry, 4070 Basel, Switzerland. matthias.nettekoven@roche.com
Guba
Wolfgang
W
Neidhart
Werner
W
Mattei
Patrizio
P
Pflieger
Philippe
P
Plancher
Jean-Marc
JM
Taylor
Sven
S
D008024:Ligands; D017476:Receptors, Neuropeptide Y / Q000187:drug effects*; D013844:Thiazoles / Q000737:chemistry / Q000494:pharmacology*
D008024:Ligands; D017476:Receptors, Neuropeptide Y; D013844:Thiazoles; C100568:neuropeptide Y5 receptor