title: [Diabetic vascular calcification and abnormal bone metabolism: the relation between bone and vascular].
abstract: High-frequency severe atherosclerosis/calcinosis is observed in diabetes mellitus and chronic dialysis, which leads to cardiovascular events. However, the effective treatment for suppressing the progression of vascular calcification has not been established. Here we review the mechanism of vascular calcification and present our findings that a first generation of bisphosphonate is useful in prevention of vascular calcification in diabetes and chronic renal failure.
authors.affiliation: University of Occupational and Environmental Health, First Department of Internal Medicine.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Okada
authors.forename: Keiko
authors.initials: K
authors.lastname: Nishida
authors.forename: Takahisa
authors.initials: T
authors.lastname: Tanikawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Hashimoto
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D001161:Arteriosclerosis / Q000473:pathology; D001842:Bone and Bones / Q000378:metabolism*; D002114:Calcinosis; D003925:Diabetic Angiopathies / Q000473:pathology*; D006801:Humans