title: Synthesis of 2'-amino-LNA purine nucleosides.
abstract: The first reported synthesis of 2'-amino-LNA purine nucleosides via a transnucleosidation is accomplished enabling the preparation of oligonucleotides incorporating 2'-amino-LNA with all four natural bases.
authors.affiliation: Santaris Pharma A/S, Hørsholm, Denmark. jra@santaris.com
authors.forename: Jacob
authors.initials: J
authors.lastname: Ravn
authors.forename: Christoph
authors.initials: C
authors.lastname: Rosenbohm
authors.forename: Signe M
authors.initials: SM
authors.lastname: Christensen
authors.forename: Troels
authors.initials: T
authors.lastname: Koch
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis*; D006151:Guanosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D011684:Purine Nucleosides / Q000138:chemical synthesis*
chemical_list: D001952:Bridged-Ring Compounds; D011684:Purine Nucleosides; D006151:Guanosine; D000241:Adenosine