title: Insertion-deletion polymorphism in the angiotensin-converting enzyme (ACE) gene among Sudanese, Somalis, Emiratis, and Omanis.
abstract: The angiotensin-converting enzyme (ACE) gene in humans contains an insertion-deletion polymorphism in its intron 16. Because of its involvement with the renin-angiotensin system, the insertion-deletion polymorphism of the ACE gene has been widely investigated in different populations and in case-control studies. However, similar studies for Arab populations are limited in number. Therefore we have investigated the frequencies of the *I and *D alleles of the ACE gene among Sudanese, Somalis, and Arab nationals of the United Arab Emirates and Oman using previously described methods. Our data indicate a preponderance of the *D allele among the Arab and African populations studied (Sudanese, 0.64; Somalis, 0.73; Emiratis, 0.61; and Omanis, 0.71).
authors.affiliation: Department of Biochemistry, Medicine and Physiology, College of Medicine, Sultan Qaboos University, Sultanate of Oman.
authors.forename: Riad A
authors.initials: RA
authors.lastname: Bayoumi
authors.forename: M
authors.initials: M
authors.lastname: Simsek
authors.forename: Taher M
authors.initials: TM
authors.lastname: Yahya
authors.forename: Sheela
authors.initials: S
authors.lastname: Bendict
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Hinai
authors.forename: Hameeda
authors.initials: H
authors.lastname: Al-Barwani
authors.forename: M O
authors.initials: MO
authors.lastname: Hassan
mesh_terms: D000351:Africa, Eastern; D000483:Alleles; D005828:Genetics, Population / Q000379:methods*; D006801:Humans; D008877:Middle East; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D007703:Peptidyl-Dipeptidase A