title: Effects of exercise and nutritional counseling in women with polycystic ovary syndrome.
abstract: This pilot study assessed the effects of exercise and nutritional counseling on hormonal, menstrual, and reproductive function in women with polycystic ovary syndrome (PCOS). Twelve females with a clinical, biochemical, and ultrasonographic diagnosis of PCOS were randomly assigned to endurance and resistance exercise plus nutritional counseling (EN) or nutritional counseling only (N) for a period of 12 weeks. Anthropometry, resting metabolic rate (RMR), selected hormones, and ovarian follicle population were measured pre and post-intervention. Following the 12 week intervention, greater decreases in sum of 2 skinfolds (p = 0.002) and a greater increase in estimated VO2 max (p = 0.017) occurred in the exercise group. Significant decreases in waist girth (p = 0.001) and insulin levels (p = 0.03) occurred in both groups. Hormonal changes were not statistically significant; however, a trend towards an improved hormonal profile, specifically sex-hormone binding globulin (EN, 39% increase; N, 8% increase) and lutenizing hormone : follicle-stimulating hormone (LH:FSH) (EN, 9% decrease; N, 27% decrease) occurred in the absence of weight loss. These findings suggest exercise and nutritional counseling may benefit the metabolic and reproductive abnormalities associated with PCOS.
authors.affiliation: University of Saskatchewan, College of Kinesiology, 87 Campus Drive, Saskatoon, SK S7N 5B2, Canada. brenda.bruner@usask.ca
authors.forename: Brenda
authors.initials: B
authors.lastname: Bruner
authors.forename: Karen
authors.initials: K
authors.lastname: Chad
authors.forename: Donna
authors.initials: D
authors.lastname: Chizen
mesh_terms: D000886:Anthropometry; D001481:Basal Metabolism; D015992:Body Mass Index; D003376:Counseling; D015444:Exercise; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D007986:Luteinizing Hormone / Q000097:blood; D009747:Nutritional Physiological Phenomena; D010807:Physical Endurance; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D012885:Skinfold Thickness; D014463:Ultrasonography
chemical_list: D007328:Insulin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone