title: [Lethal mixed intoxication with propofol in a medical layman].
abstract: The authors report on a drug fatality of a 21-year-old man with a propofol (2,6-di-isopropylphenol) dependency. Propofol was detected in tissues and body fluids using SPME-GC/MS methods. The postmortem concentrations of propofol were 364 ng/ml in urine, 71 ng/ml in heart blood and 79 ng/ml in femoral blood. The drug addict had only an autodidactic medical knowledge, but had inserted himself a permanent cannula for intravenous injection of propofol several times a day. The injection material was bought via online auctions from eBay. The case illustrates how job-related drug dependencies become indistinct due to the free access to information and goods via the Internet.
authors.affiliation: Institut für Rechtsmedizin der Universität Bonn.
authors.forename: Marco
authors.initials: M
authors.lastname: Strehler
authors.forename: Johanna
authors.initials: J
authors.lastname: Preuss
authors.forename: Heike
authors.initials: H
authors.lastname: Wollersen
authors.forename: Burkhard
authors.initials: B
authors.lastname: Madea
mesh_terms: D000328:Adult; D018686:Anesthetics, Intravenous / Q000493:pharmacokinetics / Q000506:poisoning*; D001344:Autopsy / Q000331:legislation & jurisprudence*; D062787:Drug Overdose / Q000473:pathology*; D005858:Germany; D006801:Humans; D007262:Infusions, Intravenous / Q000295:instrumentation; D020407:Internet / Q000331:legislation & jurisprudence; D008297:Male; D009293:Opioid-Related Disorders / Q000473:pathology*; D015742:Propofol / Q000493:pharmacokinetics / Q000506:poisoning*; D015819:Substance Abuse, Intravenous / Q000473:pathology*; D014018:Tissue Distribution
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol