title: A convenient synthesis of an anti-Helicobacter pylori agent, dehydrodiconiferyl alcohol.
abstract: Potential anti-Helicobacter pylori agent dehydrodiconiferyl alcohol was synthesized in 44% overall yield, starting from vanillin which could be commercially available. Carbon extension of vanillin followed by the Horner-Wadsworth-Emmons reaction, a biomolecular radical coupling reaction and DIBAL-H reduction gave dehydrodiconiferyl alcohol.
authors.affiliation: College of Pharmacy, Kyung Hee University, Seoul 130-701, Korea.
authors.forename: Kun
authors.initials: K
authors.lastname: Hu
authors.forename: Jin-Hyun
authors.initials: JH
authors.lastname: Jeong
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001547:Benzaldehydes / Q000737:chemistry; D016480:Helicobacter pylori / Q000187:drug effects; D010084:Oxidation-Reduction; D010636:Phenols / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001547:Benzaldehydes; D010636:Phenols; C080686:dehydrodiconiferyl alcohol; C100058:vanillin