[Metastatic renal failure].
A 52-year-old man, treated 15 months earlier for a poorly differentiated bronchial adenosquamous carcinoma, was admitted for oligoanuric renal failure preceded by macroscopic hematuria. Clinical and paraclinical investigations were unremarkable except ++proteinuria and mild echographic enlargement of both kidneys. Bilateral renal biopsy disclosed replacement of normal renal tissue by an adenocarcinomatous proliferation. Despite transient improvement and cessation of hemodialysis, the patient died one month later. Analysis of literature reveals that secondary kidney tumours -especially of bronchial origin- are more frequent than primary ones, but that cases of renal failure are uncommonly reported, probably because of underdiagnosis, poor prognosis and limited therapeutic issues. Features of previously published cases are listed in a synthetic table.
Cluzel
Pascal
P
Département de Médecine Interne, Néphrologie, Dialyse, Hôpital Pierre-Bérégovoy, 58000 Nevers, France. dr.cluzel@aura-auvergne.com
Enache
Ioana
I
Roche-Lachaise
Isabelle
I
Justrabo
Eve
E
D001706:Biopsy; D001984:Bronchial Neoplasms / Q000473:pathology*; D018196:Carcinoma, Adenosquamous / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D051437:Renal Insufficiency / Q000209:etiology*