title: Nephropathy, polyneuropathy, and gastroenteritis in a child with Churg-Strauss syndrome.
abstract: Churg-Strauss syndrome (CSS) is a serious but rare pauci-immune vasculitis of small- and medium-sized blood vessels. It is commonly seen in association with bronchial asthma and/or allergic disorders. The syndrome is characterized by the presence of asthma, hypereosinophilia, and vasculitis in any part of the body. Vasculitis is often associated with significant distortion of normal functions. A rather severe case of CSS in an 8-year-old Nigerian girl with asthma and allergic rhinoconjunctivitis is reported. She presented with multiple morbidities, namely, vasculitic polyneuropathy and also nephritic-nephrotic syndrome that eventuated in acute renal failure after an onset of vasculitic gastroenteritis. Routine screening of all asthmatic patients for CSS is advocated.
authors.affiliation: Paediatric Nephrology and Hypertension Unit, Obafemi Awolowo University Teaching Hospitals Complex, PMB 5538, Ile-Ife, Osun State, Nigeria. yetundeolowu@yahoo.com
authors.forename: Wasiu A
authors.initials: WA
authors.lastname: Olowu
mesh_terms: D001249:Asthma / Q000150:complications*; D002648:Child; D015267:Churg-Strauss Syndrome / Q000150:complications*; D005260:Female; D005759:Gastroenteritis / Q000209:etiology*; D006801:Humans; D009404:Nephrotic Syndrome / Q000209:etiology*; D011115:Polyneuropathies / Q000209:etiology*