title: Rhabdomyolysis in the military: recognizing late-onset very long-chain acyl Co-A dehydrogenase deficiency.
abstract: Very long-chain acyl Co-A dehydrogenase deficiency, an inborn error of lipid metabolism, is commonly thought of as a disease of infancy or early childhood. However, several cases of late-onset very long-chain acyl Co-A dehydrogenase have been reported. This report of two military men who survived basic training before their disease presentation broadens the spectrum of late-onset disease, presents two previously unreported mutations, and demonstrates the fine line between athletic, active lifestyle and severe disease presentation.
authors.affiliation: Division of Genetics, Tufts-New England Medical Center, Boston, MA 02111, USA.
authors.forename: Jodi D
authors.initials: JD
authors.lastname: Hoffman
authors.forename: Robert D
authors.initials: RD
authors.lastname: Steiner
authors.forename: Lori
authors.initials: L
authors.lastname: Paradise
authors.forename: Carey O
authors.initials: CO
authors.lastname: Harding
authors.forename: Li
authors.initials: L
authors.lastname: Ding
authors.forename: Arnold W
authors.initials: AW
authors.lastname: Strauss
authors.forename: Paige
authors.initials: P
authors.lastname: Kaplan
mesh_terms: D044942:Acyl-CoA Dehydrogenase, Long-Chain / Q000172:deficiency*; D000328:Adult; D017668:Age of Onset; D006801:Humans; D008019:Life Style; D008297:Male; D008661:Metabolism, Inborn Errors / Q000150:complications / Q000175:diagnosis*; D008889:Military Personnel; D010809:Physical Fitness; D012206:Rhabdomyolysis / Q000175:diagnosis*
chemical_list: D044942:Acyl-CoA Dehydrogenase, Long-Chain