title: Acquired alexia with agraphia syndrome in childhood.
abstract: The acquired alexia with agraphia syndrome is a conspicuous disorder of reading and writing in the absence of significant other language impairments that has mainly been recorded in adults. Pure cases are rare, with most patients displaying mild aphasic deficits. In children, acquired reading and writing disorders are generally reported as part of more encompassing aphasic syndromes affecting oral and written language equally, for example, Broca or Wernicke aphasia. Documented instances of predominant acquired reading and writing disorders in childhood are exceptional. We report an 11-year-old, right-handed boy who sustained a left temporoparieto-occipital hematoma following rupture of an arteriovenous malformation and who consecutively presented with the acquired alexia with agraphia syndrome associated with word-finding difficulties. Neuropsychologic and neurolinguistic data showed that there was no concomitant Gerstmann and/or angular gyrus syndrome. Th e recoveryfrom the anomia was quite favorable, but recovery of written language was more protracted and acted on the patient's further scholastic achievement. This case is reminiscent of a historical childhood case reported in 1939 and is consonant with adult cases in terms of lesion location and semiologic picture.
authors.affiliation: Department of Neurology, Erasme University Hospital ULB, Brussels, Belgium. ppaquier@ulb.ac.be
authors.forename: Philippe F
authors.initials: PF
authors.lastname: Paquier
authors.forename: Hyo Jung
authors.initials: HJ
authors.lastname: De Smet
authors.forename: Peter
authors.initials: P
authors.lastname: Mariën
authors.forename: Nathalie
authors.initials: N
authors.lastname: Poznanski
authors.forename: Patrick
authors.initials: P
authors.lastname: Van Bogaert
mesh_terms: D000381:Agraphia / Q000175:diagnosis* / Q000209:etiology; D001921:Brain / Q000473:pathology; D002648:Child; D004411:Dyslexia, Acquired / Q000175:diagnosis* / Q000209:etiology; D004621:Embolization, Therapeutic; D005500:Follow-Up Studies; D006406:Hematoma / Q000209:etiology; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D012422:Rupture, Spontaneous / Q000150:complications; D013577:Syndrome