Endocytic recycling pathways: emerging regulators of cell migration.
The past five years have seen a steady accumulation of data reinforcing the view that Rab-regulated recycling pathways contribute to cell migration. In particular, detailed descriptions have emerged of the mechanisms that recruit integrins and growth factor receptors to Rab4- and Rab11-driven pathways. Recent work provides new insight into the importance of particular recycling events in cell migration within a variety of physiological contexts.
Jones
Matthew C
MC
Beatson Institute for Cancer Research, (Cancer Research UK), Garscube Estate, Switchback Rd, Glasgow, G61 1BD UK.
Caswell
Patrick T
PT
Norman
Jim C
JC
D020727:ADP-Ribosylation Factors / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D002465:Cell Movement / Q000502:physiology*; D004705:Endocytosis / Q000502:physiology*; D005089:Exocytosis / Q000502:physiology; D016023:Integrins / Q000378:metabolism; D019707:Receptors, Chemokine / Q000378:metabolism; D017978:Receptors, Growth Factor / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D020691:rab GTP-Binding Proteins / Q000378:metabolism
D016023:Integrins; D019707:Receptors, Chemokine; D017978:Receptors, Growth Factor; D020727:ADP-Ribosylation Factors; D020691:rab GTP-Binding Proteins