The discovery of CCR5 receptor antagonists for the treatment of HIV infection: hit-to-lead studies.
Armour
Duncan
D
Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK.
de Groot
Marcel J
MJ
Edwards
Martin
M
Perros
Manos
M
Price
David A
DA
Stammen
Blanda L
BL
Wood
Anthony
A
D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D065100:CCR5 Receptor Antagonists; D003503:Cyclobutanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D020128:Inhibitory Concentration 50; D013329:Structure-Activity Relationship
D019380:Anti-HIV Agents; D001562:Benzimidazoles; D065100:CCR5 Receptor Antagonists; D003503:Cyclobutanes; C513586:UK-374503