[Genetics in rheumatoid arthritis (RA)].
Rheumatoid arthritis (RA) is a chronic autoimmune disease. Genetic and environmental factors are implicated in the pathogenesis of RA. In this study we describe numerous genetic phenomena that may be implicated in the etiopathogenesis of RA i.e. antigens of major histocompatibility complex, genetic linkage analysis results of whole genome scan and polymorphism of several genes coding receptors, adhesion molecules and cytokines. Genetic background plays an important role in this disorder and is connected with multiple genes.
Skretkowicz
Jadwiga
J
Uniwersytet Medyczny w Lodzi, Zakład Farmakogenetyki. jskretkowicz@pharm.am.lodz.pl
Skretkowicz-Szarmach
K
K
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000235:genetics*; D015815:Cell Adhesion Molecules / Q000235:genetics; D016207:Cytokines / Q000235:genetics; D008040:Genetic Linkage; D006801:Humans; D008285:Major Histocompatibility Complex / Q000235:genetics; D011110:Polymorphism, Genetic
D015815:Cell Adhesion Molecules; D016207:Cytokines