Genetic polymorphisms of adhesion molecules in children with severe RSV-associated diseases.
Adhesion molecules are involved in the pathophysiology of respiratory syncytial virus (RSV)-associated diseases. By testing polymorphisms within ICAM-1, VCAM-1 and E-selectin, we found no evidence for association of any polymorphism with severe RSV infections. Thus, we conclude that these genes do not predispose to severe RSV-associated diseases.
Krueger
M
M
University Children's Hospital, University of Freiburg, Mathildenstrasse 1, D-79106 Freiburg, Germany.
Puthothu
B
B
Heinze
J
J
Forster
J
J
Heinzmann
A
A
D001988:Bronchiolitis / Q000235:genetics / Q000503:physiopathology; D016022:Case-Control Studies; D015815:Cell Adhesion Molecules / Q000235:genetics*; D019040:E-Selectin; D005858:Germany; D006239:Haplotypes; D006801:Humans; D007223:Infant; D018799:Intercellular Adhesion Molecule-1 / Q000235:genetics; D015810:Linkage Disequilibrium; D011110:Polymorphism, Genetic; D018357:Respiratory Syncytial Virus Infections / Q000235:genetics* / Q000276:immunology / Q000503:physiopathology*; D012136:Respiratory Syncytial Viruses / Q000235:genetics / Q000276:immunology; D019010:Vascular Cell Adhesion Molecule-1 / Q000235:genetics
D015815:Cell Adhesion Molecules; D019040:E-Selectin; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1