title: [Familial transmission of Helicobacter pylori infection in Podlasie Region].
abstract: The purpose of the study was to assess the incidence of Helicobacter pylori infection in members of families in the Podlasie Region. The study included members of 205 families in whom IgG antibodies against H. pylori were determined. The mean number of members examined in a family was 3.07. The mean age was 16.6 years; the mean level of specific IgG antibodies was 67.35 U/ml. Of the families examined 47 (22.0%) had all members with a positive titer of antibodies against H. pylori (> 24 U/ml); in 62 (30.2%) families, all members presented a negative result of IgG antibodies against H. pylori (< 24 U/ml). Of 97 mothers examined, a positive titer of IgG was found in 77.1%. Of 33 fathers (81.8%) were seropositive. In the families with a mother seropositive, the infection in at least one child examined was revealed in 48.6% of the families, whereas in the families with a mother seronegative, all her children were healthy in 63.6% of the families. In case of a father, a positive IgG in at least one child was found in 55.5% of the families, whereas no infection in children was estabilished in 44.4%.
authors.affiliation: Zakład Pielegniarstwa Pediatrycznego AM w Białymstoku.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Maciorkowska
authors.forename: Izabela
authors.initials: I
authors.lastname: Roszko
authors.forename: Maciej
authors.initials: M
authors.lastname: Kaczmarski
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018562:Disease Transmission, Infectious / Q000706:statistics & numerical data*; D004797:Enzyme-Linked Immunosorbent Assay; D005192:Family Health; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D010287:Parent-Child Relations; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D007074:Immunoglobulin G