title: IgE-mediated hypersensitivity reaction to lignocaine - a case report.
abstract: We report a 7 year old girl who developed ipsilateral left facial swelling immediately after lignocaine injection. Skin prick test showed positive reaction to pure 2% lignocaine hydrochloride and to lignocaine oral dental gel. Specific Immunoglobulin E (Ig E) to lignocaine was detected. Lignocaine is a commonly used anaesthetic agent mainly as local anaesthesia. However type I hypersensitivity to lignocaine is rare and there have been very few cases reported in the literature.
authors.affiliation: Allergy & Immunology Research Centre, Institute for Medical Research, Kuala Lumpur.
authors.forename: A
authors.initials: A
authors.lastname: Noormalin
authors.forename: M
authors.initials: M
authors.lastname: Shahnaz
authors.forename: M
authors.initials: M
authors.lastname: Rosmilah
authors.forename: S H
authors.initials: SH
authors.lastname: Mujahid
authors.forename: B S
authors.initials: BS
authors.lastname: Gendeh
mesh_terms: D000766:Anesthesia, Dental / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000276:immunology; D002648:Child; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced* / Q000276:immunology; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008012:Lidocaine / Q000009:adverse effects* / Q000276:immunology; D012882:Skin Tests
chemical_list: D000779:Anesthetics, Local; D007073:Immunoglobulin E; D008012:Lidocaine