title: Concepts in molecular dermatotoxicology.
abstract: In the recent years, molecular research has successfully elucidated some of the major mechanisms through which environmental noxae damage human skin. From this knowledge, novel concepts for skin protection have been developed. Here, we provide a brief overview of some of the most exciting and intriguing concepts in molecular dermatotoxicology.
authors.affiliation: Department of Dermatology and Allergology, RWTH Aachen, Aachen, Germany. Hans.Merk@post.rwth-aachen.de
authors.forename: Hans F
authors.initials: HF
authors.lastname: Merk
authors.forename: Jens M
authors.initials: JM
authors.lastname: Baron
authors.forename: Ruth
authors.initials: R
authors.lastname: Heise
authors.forename: Ellen
authors.initials: E
authors.lastname: Fritsche
authors.forename: Peter
authors.initials: P
authors.lastname: Schroeder
authors.forename: Josef
authors.initials: J
authors.lastname: Abel
authors.forename: Jean
authors.initials: J
authors.lastname: Krutmann
mesh_terms: D002462:Cell Membrane / Q000528:radiation effects; D004249:DNA Damage / Q000528:radiation effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D003885:Dermotoxins / Q000494:pharmacology; D004342:Drug Hypersensitivity / Q000209:etiology; D006801:Humans; D007259:Infrared Rays; D008563:Membrane Lipids / Q000528:radiation effects; D010655:Phenylenediamines / Q000494:pharmacology; D012867:Skin / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology; D014466:Ultraviolet Rays
chemical_list: D003885:Dermotoxins; D008563:Membrane Lipids; D010655:Phenylenediamines; C029728:4-phenylenediamine