title: False-positive results of enzyme immunoassays for human immunodeficiency virus in patients with uncomplicated malaria.
abstract: Malaria may impact upon human immunodeficiency virus (HIV) test results. We evaluated two HIV enzyme immunoassays (EIAs) by testing 1,965 Ugandans with malaria. We found poor positive predictive values (53% and 76%), particularly with younger age. Combining EIAs eliminated false positives but missed 21% of true positives. Performance of HIV EIAs in malaria may be unsatisfactory.
authors.affiliation: Department of Medicine, Makerere University Medical School, Kampala, Uganda.
authors.forename: Anne F
authors.initials: AF
authors.lastname: Gasasira
authors.forename: Grant
authors.initials: G
authors.lastname: Dorsey
authors.forename: Moses R
authors.initials: MR
authors.lastname: Kamya
authors.forename: Diane
authors.initials: D
authors.lastname: Havlir
authors.forename: Moses
authors.initials: M
authors.lastname: Kiggundu
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenthal
authors.forename: Edwin D
authors.initials: ED
authors.lastname: Charlebois
mesh_terms: D015492:AIDS Serodiagnosis; D000367:Age Factors; D005189:False Positive Reactions; D015658:HIV Infections / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D008288:Malaria / Q000150:complications*; D011237:Predictive Value of Tests; D014454:Uganda