[Significance of some otologic function tests in diagnosis of Meniere's disease].
OBJECTIVE
To investigate the significance of vestibular function battery and electrocochleogram on diagnosis of Meniere's disease.


METHODS
Patients with Meniere's disease were given pure tone hearing threshold test, auditory brainstem responses (ABR), electrocochleogram (ECoG), vestibular bithermal caloric test and vestibular evoked myogenic potentials (VEMP) test.


RESULTS
(1) As for the bithermal caloric test, the percentage of the abnormal canal paresis (CP) at three durations, i.e. , 0 to approximately 5 years, 6 to approximately 10 years and over 11 years were 56.9%, 75.9% and 61.6% respectively. The total positive rate was 50.0%. CP and duration of Meniere's disease had low correlation (P < 0.05). (2) The percentage of the abnormal VEMP at three durations, i.e., 0-5 years,6-10 years and over 11 years were 57.4%, 60% and 57.1% respectively. The total positive rate was 58.0%. The duration of Meniere 's disease with normal and abnormal VEMP had no significant difference( P >0.05). (3) The percentage of the abnormal ECoG at three durations, i.e., 0-5 years, 6-10 years and over 11 years were 72.1%, 73.3% and 81.3% (49/68,22/30 and 13/16) respectively. The total positive rate was 76.9%. The duration of Meniere's disease with normal and abnormal ECoG had no significant difference (P >0.05).


CONCLUSIONS
Diagnosis of Meniere's disease is mainly based on the medical history. If it could combine with ECoG, bithermal caloric test and VEMP, the diagnosis would be earlier and more accurate.
Wu
Ziming
Z
Department of Otolaryngology-Head and Neck Surgery, General Hospital of Chinese PLA, The Otolaryngology Institute of Chinese PLA, Beijing, 100853, China. zimingwu@163.com
Zhang
Suzhen
S
Zhou
Na
N
Yi
Fei
F
Chen
Aiting
A
Xie
Sujiang
S
Yang
Weiyan
W
Han
Dongyi
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002150:Caloric Tests; D002648:Child; D004576:Electromyography; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged; D058585:Vestibular Evoked Myogenic Potentials; D014724:Vestibular Function Tests; D055815:Young Adult