title: [Collagen injection for augmentation of periprosthetic leakage after tracheo-esophageal voice restoration].
abstract: After laryngectomy the majority of patients receive a vocal rehabilitation by tracheo-esophageal puncture and insertion of voice prosthesis. Periprosthetic leakage causing aspiration represents a well known complication and is frequently treated by temporary removal of the prosthesis with shrinkage of the shunt. Here we describe 10 patients with such a leakage treated by collagen injection for periprosthetic tissue augmentation. A mean of 1,6 injections were necessary for complete control of the leakage. The injection was well tolerated and was found effective for median period of 9,3 months. In our hands the periprosthetic collagen injection represents an effective and well tolerated procedure for temporary augmentation of tracheo-esophageal leakage in post-laryngectomy patients. However, alternative fillers without pre-testing necessity and longer augmentation intervals should be considered.
authors.affiliation: HNO-Universitätsklinikum, Düsseldorf.
authors.forename: T K
authors.initials: TK
authors.lastname: Hoffmann
authors.forename: P
authors.initials: P
authors.lastname: Sommer
authors.forename: H
authors.initials: H
authors.lastname: Bier
mesh_terms: D003094:Collagen / Q000008:administration & dosage*; D004947:Esophagus / Q000187:drug effects; D006801:Humans; D007267:Injections; D007825:Laryngectomy / Q000534:rehabilitation*; D007831:Larynx, Artificial; D011015:Pneumonia, Aspiration / Q000534:rehabilitation*; D011183:Postoperative Complications / Q000534:rehabilitation*; D011475:Prosthesis Failure; D017755:Prosthesis Fitting / Q000379:methods*; D014139:Tracheostomy / Q000534:rehabilitation*
chemical_list: D003094:Collagen