title: Gastroesophageal reflux and laryngopharyngeal reflux in patients with sleep-disordered breathing.
abstract: OBJECTIVE
  To assess the relationship of gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) with obstructive sleep apnea (OSA).
  
  
  METHODS
  Thirty-seven sleep-disordered breathing (SDB) patients underwent polysomnography (PSG) and dual-channel pH probe testing. LPR was defined as greater than 6.9 proximal reflux episodes or reflux area index (RAI) greater than 6.3. GER was defined as greater than 4% of time below pH 4.0.
  
  
  RESULTS
  OSA was present in 28 patients. Twenty-three patients had LPR (66.7% of snorers, 60.7% of OSA patients). Twenty-one patients had GER (33.3% of snorers, 64.3% of OSA patients). Body mass index (BMI) correlated positively with respiratory disturbance index (RDI) (r = 0.67, P < 0.001). BMI did not correlate with pH probe parameters. OSA presence/severity did not correlate with LPR or GER. Supine LPR and GER events did not correlate with OSA presence/severity.
  
  
  CONCLUSIONS
  Gastric acid reflux is prevalent in SDB patients. Direct correlations between reflux and PSG parameters were not identified.
  
  
  METHODS
  B-2b.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Emory Clinic, 1365A Clifton Road NE, Atlanta, GA 30322, USA.
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Wise
authors.forename: Justin C
authors.initials: JC
authors.lastname: Wise
authors.forename: John M
authors.initials: JM
authors.lastname: DelGaudio
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015897:Comorbidity; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007013:Hypopharynx; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases; D012891:Sleep Apnea Syndromes / Q000453:epidemiology*; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology