Endoscopic therapy of benign pyloric stenosis and gastric outlet obstruction.
OBJECTIVE
To examine the short and long-term success rates of balloon dilation of pyloric stenosis.


RESULTS
Several large studies have demonstrated high rates of success for the relief of symptoms from pyloric stenosis using through-the-scope balloons. These dilating balloons readily increase the diameter of the stenotic pylorus on average from 6 to 16 mm. Patients who require more than two dilations are at high risk of endoscopic failure and the need for surgical intervention. Rapid re-stenosis rates are observed in patients with malignant pyloric obstruction. Since many patients with benign pyloric stenosis have underlying ulcer disease, helicobacter infection is a relatively common finding. Eradication of this infection at the time of balloon dilation will ensure higher long-term success rates.


CONCLUSIONS
In summary, benign pyloric stenosis can be readily treated with endoscopic balloon dilation and should be the first-line therapy.
Yusuf
Tony E
TE
GI Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Brugge
William R
WR
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002404:Catheterization; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D016481:Helicobacter Infections / Q000150:complications / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000150:complications / Q000382:microbiology; D011707:Pyloric Stenosis / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome