title: [Systemic inflammation after operations on the open heart: significance of a microbial factor].
abstract: The given review of the literature discusses, from the present standpoints, the pathogenetic, clinical, and diagnostic aspects of a systemic inflammatory reaction developing during cardiac surgery under extracorporeal circulation. There is evidence that endogenous infection is of importance in developing systemic inflammation during cardiosurgical interventions. Current approaches to the early diagnosis of systemic bacterial inflammation, by applying the procalcitonin test and the chromatographic mass-chromatographic technique are proposed. The prevention of systemic inflammation and its sequels is considered.
authors.forename: D A
authors.initials: DA
authors.lastname: Popov
authors.forename: N V
authors.initials: NV
authors.lastname: Beloborodova
authors.forename: M B
authors.initials: MB
authors.lastname: Iarustovskiĭ
mesh_terms: D015415:Biomarkers / Q000032:analysis; D002116:Calcitonin / Q000032:analysis; D015740:Calcitonin Gene-Related Peptide; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D016207:Cytokines / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D011498:Protein Precursors / Q000032:analysis; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control
chemical_list: D015415:Biomarkers; C000606589:CALCA protein, human; D016207:Cytokines; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide