title: A preliminary study on the occurrence and behavior of sulfonamides, ofloxacin and chloramphenicol antimicrobials in wastewaters of two sewage treatment plants in Guangzhou, China.
abstract: Wastewater samples collected from two sewage treatment plants (STPs) in Guangzhou, China were acidified, solid-phase extracted (SPE) with Oasis HLB cartridges, followed by instrumental measurement by high performance liquid chromatography (HPLC) coupled with a diode array UV detector (DAD) and a fluorescence detector (FLD) for the occurrence and fate of antimicrobial compounds sulfadiazine (SDZ), sulfamethoxazole (SMX), ofloxacin (OFX) and chloramphenicol (CAP). Antimicrobials have been detected at 5.10-5.15, 5.45-7.91, 3.52-5.56 and 1.73-2.43 microg L(-1) for SDZ, SMX, OFX and CAP in the raw sewages of the two STPs, respectively. The concentrations of antimicrobials do not show substantial changes after preliminary mechanical sedimentation. No quantifiable sulfonamides and chloramphenicol have been identified, and >85% of ofloxacin has been removed in the effluents after activated sludge treatment in the two STPs, indicating that activated sludge treatment is effective and necessary to remove antimicrobial substances in municipal sewage.
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, PR China.
authors.forename: Xianzhi
authors.initials: X
authors.lastname: Peng
authors.forename: Zhendi
authors.initials: Z
authors.lastname: Wang
authors.forename: Wenxing
authors.initials: W
authors.lastname: Kuang
authors.forename: Jianhua
authors.initials: J
authors.lastname: Tan
authors.forename: Ken
authors.initials: K
authors.lastname: Li
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D002681:China; D002701:Chloramphenicol / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D015242:Ofloxacin / Q000032:analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012722:Sewage / Q000737:chemistry*; D013449:Sulfonamides / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification
chemical_list: D000900:Anti-Bacterial Agents; D012722:Sewage; D013449:Sulfonamides; D014874:Water Pollutants, Chemical; D002701:Chloramphenicol; D015242:Ofloxacin