Visualisation of enantiomers via insertion of a BIRD module in X-H correlation experiments in chiral liquid crystal solvent.
Several 13C-1H NMR techniques are derived simplifying the visualisation of enantiomers in chiral ordering solvents. They proceed through various heteronuclear 2D experiments where a bilinear rotation decoupling sequence (BIRD) is inserted in the middle of the t1 evolution period. In this way, the small couplings are refocused while the large couplings are preserved. The methods allow extracting precise values of one-bond carbon-proton residual dipolar couplings for each enantiomer out of unresolved proton-coupled 13C or carbon-coupled 1H spectra. Illustrative examples are analysed and discussed using various pulse sequences.
Ziani
L
L
Laboratoire de RMN en milieu orienté, Université Paris-Sud 11, ICMMO, UMR CNRS 8182, Bat. 410, 91405 Orsay cedex, France.
Courtieu
J
J
Merlet
D
D
D000465:Algorithms; D007536:Isomerism; D050866:Liquid Crystals / Q000032:analysis* / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D012997:Solvents / Q000737:chemistry*; D013223:Statistics as Topic
D012997:Solvents