Effects of diacylglycerol oil on adiposity in obese children: initial communication.
Several studies have shown that diacylglycerol (DAG) oil may suppress accumulation of body fat in adults compared to triacylglycerol (TAG) oil. In this study, we investigated the effect of DAG oil as part of dietetic therapy in obese children. The participants were 11 male and female obese children who were under treatment at the outpatient clinic (four boys, seven girls, age: 7-17 years old). Daily-use cooking oil was changed to DAG oil, and the effects on abdominal fat areas, adipocytokines, and serum lipids were investigated. The total and subcutaneous fat areas significantly decreased in the 5th month after ingestion of DAG oil. Leptin was significantly lower than the initial level after ingestion of DAG oil. The ingestion of DAG oil decreased both the abdominal fat area and leptin in obese children, suggesting that DAG oil prevents obesity in children as well as in adults.
Matsuyama
Takeshi
T
Department of Pediatrics, Fussa Hospital, Tokyo, Japan.
Shoji
Kentaro
K
Watanabe
Hiroyuki
H
Shimizu
Mariko
M
Saotome
Yumiko
Y
Nagao
Tomonori
T
Matsuo
Noboru
N
Hase
Tadashi
T
Tokimitsu
Ichiro
I
Nakaya
Noriaki
N
D050153:Abdominal Fat; D017667:Adipocytes / Q000378:metabolism; D050154:Adiposity; D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D016207:Cytokines / Q000097:blood; D004075:Diglycerides / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D050152:Intra-Abdominal Fat; D007657:Ketone Bodies / Q000097:blood; D020738:Leptin / Q000378:metabolism; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000178:diet therapy*; D013223:Statistics as Topic
D001786:Blood Glucose; D016207:Cytokines; D004075:Diglycerides; D007328:Insulin; D007657:Ketone Bodies; D020738:Leptin; D008055:Lipids