title: Oncogenic osteomalacia associated with an occult phosphaturic mesenchymal tumour: clinico-radiologico-pathological correlation and ultrastructural studies.
abstract: A middle-aged man presented with bone pain at multiple sites due to tumour-induced osteomalacia. The underlying occult phosphaturic mesenchymal tumour was identified by octreotide scan 5 years after presentation and confirmed by computed tomography. Tumour resection resulted in normalisation of blood chemistry and bone densitometry. Clinico-radiologico-pathological correlation and ultrastructural studies of the tumour threw light on the pathogenesis and pathophysiology of this rare disease.
authors.affiliation: Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong. fmfcheung@gmail.com
authors.forename: F M F
authors.initials: FM
authors.lastname: Cheung
authors.forename: L
authors.initials: L
authors.lastname: Ma
authors.forename: W C
authors.initials: WC
authors.lastname: Wu
authors.forename: T H
authors.initials: TH
authors.lastname: Siu
authors.forename: P T
authors.initials: PT
authors.lastname: Choi
authors.forename: Y P
authors.initials: YP
authors.lastname: Tai
mesh_terms: D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D018204:Neoplasms, Connective and Soft Tissue / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D010018:Osteomalacia / Q000209:etiology*; D010710:Phosphates / Q000652:urine*; D011859:Radiography
chemical_list: D010710:Phosphates; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23