title: [Clinical experience of the use of autologous mononuclear bone marrow cells in patients with ischemic heart disease and dilated cardiomyopathy].
abstract: Between March 2003 and February 2005 cell therapy with mononuclear bone marrow cells (MBMC) was used in 38 and 4 patients with ischemic heart disease and dilated cardiomyopathy, respectively. Intracardiac administration of MBMC (87+/-12 millions) was carried out during coronary artery bypass surgery and/or left ventricular aneurysm resection (n=25) or in cardiac catheterization laboratory (n=17). For verification of cells fixation they were labeled with "Ceretec" 99mTc-HMPAO. Accumulation of labeled cells after 24 hours was 1.6+/-0.001%. After 6 months parameters of intracardiac hemodynamics and transitory myocardial perfusion defects improved significantly in all patients with ischemic heart disease.
authors.forename: Sh D
authors.initials: ShD
authors.lastname: Akhmedov
authors.forename: V E
authors.initials: VE
authors.lastname: Babokin
authors.forename: V V
authors.initials: VV
authors.lastname: Riabov
authors.forename: T E
authors.initials: TE
authors.lastname: Suslova
authors.forename: V I
authors.initials: VI
authors.lastname: Chernov
authors.forename: S I
authors.initials: SI
authors.lastname: Sazonova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Rogovskaia
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Korkin
authors.forename: A P
authors.initials: AP
authors.lastname: Motreva
authors.forename: V M
authors.initials: VM
authors.lastname: Shipulin
authors.forename: R S
authors.initials: RS
authors.lastname: Karpov
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation / Q000379:methods*; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology / Q000628:therapy*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000637:transplantation; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000628:therapy*; D019690:Technetium Tc 99m Exametazime / Q000032:analysis; D016896:Treatment Outcome
chemical_list: D019690:Technetium Tc 99m Exametazime