title: Impact of polypropylene amount on functional outcome and quality of life after inguinal hernia repair by the TAPP procedure using pure, mixed, and titanium-coated meshes.
abstract: BACKGROUND
  Laparoscopic inguinal hernia repair requires the use of prosthetic material. This prospective, single-center study was intended to investigate the impact of the amount of polypropylene (PP) mesh used in hernia repair on functional results and quality of life.
  
  
  METHODS
  For this series, 672 consecutive patients with primary inguinal hernia undergoing transabdominal preperitoneal hernia repair (TAPP) using a heavyweight PP mesh (Prolene 10 x 15 cm, 1.5 g, group I, n = 232), a mixed PP- and Polyglactin mesh (Vypro II, 10 x 15 cm, 0.53 g, group II, n = 217), or a light-weight titanized PP mesh (Ti-Mesh, 10 x 15 cm, 0.24 g, group III, n = 223) were compared in terms of postoperative complications (seroma, wound healing disorders), quality of life score (pain development, physical condition, urologic disorders), and hernia recurrence.
  
  
  RESULTS
  During a 12-month follow-up there were no significant differences in the recurrence rate (1.3%-1.7%). Patients with a pure PP mesh (group I) showed significantly more postoperative seromas (12.1% versus 4.1%/1.8%), foreign body sensations (9.1% versus 5.5%/3.5%), and sensitivity to weather changes (5.6% versus 3.2%/2.2%) compared to groups II and III. In all groups, the quality of life score was improved postoperatively. However, among those patients in our series with few preoperative complaints, the postoperative quality of life was worsened when heavy-weight PP meshes (group I+II) were used but significantly improved when light-weight titanized PP meshes were used.
  
  
  CONCLUSIONS
  Comparable functional results, fewer postoperative complications, and improved quality of life can be achieved by reducing the amount of PP in meshes used for laparoscopic hernia repair by TAPP procedure.
authors.affiliation: Department of General Surgery, Herz-Jesu-Hospital Muenster-Hiltrup, Westfalenstr. 109, D-48165, Muenster, Germany. chirurgie@herz-jesu-kh-ms.de
authors.forename: Ruediger
authors.initials: R
authors.lastname: Horstmann
authors.forename: Matthias
authors.initials: M
authors.lastname: Hellwig
authors.forename: Claus
authors.initials: C
authors.lastname: Classen
authors.forename: Susanne
authors.initials: S
authors.lastname: Röttgermann
authors.forename: Daniel
authors.initials: D
authors.lastname: Palmes
mesh_terms: D000328:Adult; D004867:Equipment Design; D005260:Female; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011126:Polypropylenes; D011184:Postoperative Period; D011446:Prospective Studies; D019736:Prostheses and Implants; D011788:Quality of Life; D020127:Recovery of Function; D012008:Recurrence; D013526:Surgical Mesh; D014025:Titanium
chemical_list: D011126:Polypropylenes; D014025:Titanium