title: Brain abscess due to Scedosporium apiospermum in a non immunocompromised child.
abstract: Scedosporium apiospermum is a filamentous fungi that commonly causes cutaneous infection. In certain circumstances, S. apiospermum can also cause invasive disease, which can involve the central nervous system (CNS). When the CNS becomes involved, treatment is difficult, therapeutic options are limited and the prognosis is poor. Early identification and treatment can decrease the mortality rate. Here we present a case of brain abscess with chronic suppurative otitis media, caused by S. apiospermum. This is the first such case report from Nepal. We could identify the organism only post mortem. We could not save the patient, probably due to delay in diagnosis.
authors.affiliation: Department of Clinical Microbiology, Pondicherry Institute of Medical Sciences, Pondicherry - 605 006, India.
authors.forename: A
authors.initials: A
authors.lastname: Acharya
authors.forename: A
authors.initials: A
authors.lastname: Ghimire
authors.forename: B
authors.initials: B
authors.lastname: Khanal
authors.forename: S
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: N
authors.initials: N
authors.lastname: Kumari
authors.forename: R
authors.initials: R
authors.lastname: Kanungo
mesh_terms: D000617:Aminoglycosides / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D002511:Cephalosporins / Q000627:therapeutic use; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D009390:Nepal; D010034:Otitis Media with Effusion / Q000175:diagnosis; D021681:Scedosporium / Q000302:isolation & purification*
chemical_list: D000617:Aminoglycosides; D000935:Antifungal Agents; D002511:Cephalosporins