title: Supercritical fluid extraction of limonoid glucosides from grapefruit molasses.
abstract: Limonoid glucosides (primarily limonin 17-beta-D-glucopyranoside, LG) were extracted from grapefruit molasses by supercritical fluid extraction using a supercritical carbon dioxide-ethanol (SC CO(2)-ethanol) system. Extraction conditions to maximize the yield of LG were determined by varying pressure, temperature, ethanol concentration, and extraction time. The highest yield of LG at 0.61 mg/g molasses was obtained at a pressure 48.3 MPa, a temperature of 50 degrees C, 10% ethanol (X(Eth) = 0.1), and 40 min of extraction time at a flow rate of 5.0 L/min. The results demonstrated that SC CO(2) extraction of limonoid glucosides from grapefruit molasses has practical significance for commercial production.
authors.affiliation: Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, College Station, 77845, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Yu
authors.forename: Deepak V
authors.initials: DV
authors.lastname: Dandekar
authors.forename: Romeo T
authors.initials: RT
authors.lastname: Toledo
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Singh
authors.forename: Bhimanagouda S
authors.initials: BS
authors.lastname: Patil
mesh_terms: D025924:Chromatography, Supercritical Fluid; D032083:Citrus paradisi / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D005960:Glucosides / Q000302:isolation & purification*; D036701:Limonins / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D005960:Glucosides; D036701:Limonins; D010936:Plant Extracts