The phenomenon of apoptosis in the course of experimental trichinellosis in mice.
Mice infected with 200 Trichinella spiralis larvae were killed at 3-69 days post infection (dpi) and the jejunum and masseter muscles were sectioned in a cryostat and examined in the Tunell method with "In situ Cell Detected Kid POD" of Boehringer-Mannheim. Data concering the exact localization and dynamic of apoptic cells in both organs are presented. The authors conclude that apoptosis plays a important role in the pathogenesis of trichinellosis.
Karmańska
K
K
W Stefański Institute of Parasitology, Polish Academy Sciences, Wrocław.
Houszka
M
M
Piekarska
J
J
D000818:Animals; D017209:Apoptosis; D004195:Disease Models, Animal; D006790:Host-Parasite Interactions; D007150:Immunohistochemistry; D007411:Intestinal Diseases, Parasitic / Q000473:pathology*; D007583:Jejunum / Q000469:parasitology*; D008406:Masseter Muscle / Q000469:parasitology*; D051379:Mice; D008815:Mice, Inbred Strains; D017160:Trichinella spiralis / Q000166:cytology / Q000502:physiology; D014235:Trichinellosis / Q000473:pathology*