Presacral cystic neuroblastoma: case report and review of the literature.
Cystic neuroblastoma (CN) is highly unusual; since 2005 only 55 cases have been reported in the medical literature. The authors report a case of pelvic (presacral) CN in a 2-month-old boy. Computed tomography scan confirmed a cystic, septated, and encapsulated mass. Complete tumor excision was achieved. Histopathology diagnosed a stroma-poor and undifferentiated neuroblastoma with multiple calcifications. meta-iodobenzylguanidine scan, radionuclide bone, and a bone marrow aspiration were normal. N-myc amplification was absent. The infant was classified stage I neuroblastoma and received no further therapy (4 y of follow-up). To the authors' knowledge, this is the first report of a CN in a pelvic-presacral location.
D'Alessio
Antonio
A
Department of Pediatric Surgery, Azienda Ospedaliera di Legnano, Legnano, Italy. chirurgia.pediatrica@aolegnano.it
Piro
Eugenia
E
Beretta
Fabio
F
Abati
Laura
L
Brugnoni
Marta
M
Assi
Agnese
A
Luksch
Roberto
R
D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010386:Pelvic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D012445:Sacrococcygeal Region / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome