Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin.
Gilard
M
M
Arnaud
B
B
Le Gal
G
G
Abgrall
J F
JF
Boschat
J
J
D000368:Aged; D017130:Angioplasty / Q000009:adverse effects / Q000379:methods; D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D001241:Aspirin / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D000077144:Clopidogrel; D003327:Coronary Disease / Q000150:complications / Q000235:genetics / Q000378:metabolism* / Q000601:surgery; D065731:Cytochrome P-450 CYP2C19; D004336:Drug Antagonism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008840:Microfilament Proteins / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D009853:Omeprazole / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D010750:Phosphoproteins / Q000378:metabolism*; D010766:Phosphorylation / Q000187:drug effects; D015539:Platelet Activation / Q000187:drug effects* / Q000235:genetics; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D010979:Platelet Function Tests / Q000379:methods; D020641:Polymorphism, Single Nucleotide; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D013927:Thrombosis / Q000209:etiology / Q000235:genetics / Q000378:metabolism; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000098662:Vasodilator-Stimulated Phosphoprotein
D015815:Cell Adhesion Molecules; D004791:Enzyme Inhibitors; D008840:Microfilament Proteins; D010750:Phosphoproteins; D010975:Platelet Aggregation Inhibitors; D000098662:Vasodilator-Stimulated Phosphoprotein; D000077144:Clopidogrel; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D009853:Omeprazole; D013988:Ticlopidine; D001241:Aspirin