title: Rough set feature selection and rule induction for prediction of malignancy degree in brain glioma.
abstract: The degree of malignancy in brain glioma is assessed based on magnetic resonance imaging (MRI) findings and clinical data before operation. These data contain irrelevant features, while uncertainties and missing values also exist. Rough set theory can deal with vagueness and uncertainty in data analysis, and can efficiently remove redundant information. In this paper, a rough set method is applied to predict the degree of malignancy. As feature selection can improve the classification accuracy effectively, rough set feature selection algorithms are employed to select features. The selected feature subsets are used to generate decision rules for the classification task. A rough set attribute reduction algorithm that employs a search method based on particle swarm optimization (PSO) is proposed in this paper and compared with other rough set reduction algorithms. Experimental results show that reducts found by the proposed algorithm are more efficient and can generate decision rules with better classification performance. The rough set rule-based method can achieve higher classification accuracy than other intelligent analysis methods such as neural networks, decision trees and a fuzzy rule extraction algorithm based on Fuzzy Min-Max Neural Networks (FRE-FMMNN). Moreover, the decision rules induced by rough set rule induction algorithm can reveal regular and interpretable patterns of the relations between glioma MRI features and the degree of malignancy, which are helpful for medical experts.
authors.affiliation: Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240, China. wangxiangyang@sjtu.org
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Richard
authors.initials: R
authors.lastname: Jensen
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001932:Brain Neoplasms / Q000145:classification / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003658:Decision Making, Computer-Assisted; D005260:Female; D005910:Glioma / Q000145:classification / Q000473:pathology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests