title: Bilophila wadsworthiain brain abscess: case report.
abstract: A case of a patient with a 20-year history of chronic otitis media complicated by cholesteatoma and brain abscess is described. A CT scan with contrast material showed three abscess cavities in the right cerebellar hemisphere. A culture from a specimen of the cholesteatoma yielded a significant amount of growth of Bilophila wadsworthia, Bacteroides fragilis and Prevotella oris and a moderate growth of alpha-streptococci and Staphylococcus simulans. From the pus of the brain abscess we also isolated numerous Bilophila wadsworthia, Bacteroides fragilis and Prevotella oris and some Prevotella buccae and Peptostreptococcus anaerobius. No aerobes were present. The patient underwent a craniotomy and the biggest abscess was removed together with the capsule. The antimicrobial therapy included penicillin plus metronidazole and later augmentin. The result of the treatment was a complete cure and total recovery of the patient. This is the first documentation of isolation of B. wadsworthia in chronic otitis media and in brain abscess.
authors.affiliation: Anaerobic Laboratory, National Center of Infectious and Parasitic Diseases, Department of Microbiology, Sofia, Bulgaria.
authors.forename: M
authors.initials: M
authors.lastname: Marina
authors.forename: K
authors.initials: K
authors.lastname: Ivanova
authors.forename: M
authors.initials: M
authors.lastname: Ficheva
authors.forename: G
authors.initials: G
authors.lastname: Fichev