Simultaneous determination of benzophenone-type UV filters in water and soil by gas chromatography-mass spectrometry.
A novel method has been developed to simultaneously determine and quantify seven organic UV filters employing liquid (solid)-liquid extraction, derivatization with N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) and gas chromatography with mass spectrometric detection in various environmental matrices. The UV filters determined were: benzophenone (BP), benzhydrol (BH), 4-hydroxybenzophenone (HBP), 2-hydroxy-4-methoxybenzophenone (HMB), 2,4-dihydroxybenzophenone (DHB), 2,2'-dihydroxy-4-methoxybenzophenone (DHMB) and 2,3,4-trihydroxylbenzophenone (THB). Under optimal conditions, the analysis required 23 min and good linearity over the range of 10-2,500 ng/L in water and 100-25,000 ng/kg in soil for each UV filter obtained. The high recovery (62-114% and 60-125% for water and soil samples, respectively) and the low RSD values (less than 13.9 and 17.2% for water and soil samples, respectively) indicated the high performance of this method. The method detection limits (MDLs) were relatively low, ranging from 5 to 100 ng/L or kg and quantification limits ranged between 25 and 500 ng/L or kg for all test compounds. This validated method was applied in the analysis of seven BP-type UV filters collecting water and soil samples in Korea, between April and May 2003. The overall concentration of UV filters in the soil sample (500-18,380 ng/kg) was highly distributed in water sample (27-204 ng/L). The established method was successfully applied to monitor the residue measurement of the BP-type UV filters in environmental water and soil samples.
Jeon
Hee-Kyung
HK
Toxicology Laboratory, Bioanalysis and Biotransformation Research Center, Korea Institute of Science & Technology P.O. Box 131, Chengryang, Seoul 130-650, South Korea.
Chung
Yong
Y
Ryu
Jae-Chun
JC
D000081:Acetamides; D001577:Benzophenones / Q000032:analysis* / Q000737:chemistry; D005374:Filtration; D005463:Fluoroacetates; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D005843:Geography; D007723:Korea; D015394:Molecular Structure; D012987:Soil / Q000032:analysis*; D013473:Sunscreening Agents / Q000032:analysis* / Q000737:chemistry; D014269:Trifluoroacetic Acid / Q000032:analysis / Q000737:chemistry; D014297:Trimethylsilyl Compounds / Q000032:analysis / Q000737:chemistry; D014466:Ultraviolet Rays; D014867:Water / Q000032:analysis* / Q000737:chemistry
D000081:Acetamides; D001577:Benzophenones; D005463:Fluoroacetates; D012987:Soil; D013473:Sunscreening Agents; D014297:Trimethylsilyl Compounds; D014867:Water; C086665:N-methyl-N-(trimethylsilyl)trifluoroacetamide; C047723:benzophenone; D014269:Trifluoroacetic Acid