[Cerebral vein thrombosis as a complication of a florid ulcerative colitis].
BACKGROUND
Thromboembolic episode, especially cerebral vein thrombosis, is a rare extraintestinal complication of ulcerative colitis. In world literature less than 100 cases are reported. Although the existence of coagulation alterations and fibrinolysis have been suggested, the exact mechanism of hypercoagulability in patients with ulcerative colitis is still unknown.


METHODS
The authors report of a 35-year-old female patient with ulcerative colitis, that has existed for several years. She developed strong cephalgias without further neurologic symptoms in an acute attack of her disease. Magnetic resonance imaging led to the diagnosis of an extensive acute cerebral vein thrombosis. Other possible reasons for a coagulopathy were excluded.


CONCLUSIONS
Cerebral vein thrombosis is a rare, but severe complication of ulcerative colitis. Thus, the presence of neurologic symptoms in a patient with known ulcerative colitis should lead to immediate diagnosis and treatment.
Palm
Hans-Georg
HG
Medizinische Klinik II, Krankenhaus Barmherzige Brüder, Regensburg.
Bauer
Andrea
A
Weinerth
Jutta
J
Wiedmann
Karl Hermann
KH
D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis; D003113:Colonoscopy; D003422:Critical Care; D004569:Electroencephalography; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D010314:Partial Thromboplastin Time; D010644:Phenprocoumon / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin; D010644:Phenprocoumon