title: The discovery of CCR5 receptor antagonists for the treatment of HIV infection: hit-to-lead studies.
authors.affiliation: Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK.
authors.forename: Duncan
authors.initials: D
authors.lastname: Armour
authors.forename: Marcel J
authors.initials: MJ
authors.lastname: de Groot
authors.forename: Martin
authors.initials: M
authors.lastname: Edwards
authors.forename: Manos
authors.initials: M
authors.lastname: Perros
authors.forename: David A
authors.initials: DA
authors.lastname: Price
authors.forename: Blanda L
authors.initials: BL
authors.lastname: Stammen
authors.forename: Anthony
authors.initials: A
authors.lastname: Wood
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D065100:CCR5 Receptor Antagonists; D003503:Cyclobutanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D020128:Inhibitory Concentration 50; D013329:Structure-Activity Relationship
chemical_list: D019380:Anti-HIV Agents; D001562:Benzimidazoles; D065100:CCR5 Receptor Antagonists; D003503:Cyclobutanes; C513586:UK-374503