Restrictive mitral inflow pattern is a strong independent predictor of lack of viable myocardium after a first acute myocardial infarction.
In patients with acute myocardial infarction (AMI) a restrictive mitral inflow pattern successfully predicts clinical outcome. The impact of myocardial viability on the mitral inflow velocities, however, is unknown. One hundred and forty-one patients with a first AMI underwent two-dimensional, Doppler and dobutamine stress echocardiography (DSE). Patients were classified into two groups based on Doppler measurement of left ventricular filling: a restrictive group (18 patients), and a non-restrictive group (123 patients). In the non-restrictive group, myocardial viability at DSE was found in 56 patients, while in the restrictive group only three patients showed contractile reserve (46% vs. 16%, p<0.03). The multivariate logistic regression analysis demonstrated that restrictive mitral inflow pattern was a strong independent predictor of lack of viable myocardium (OR=12.45, p<0.001).
Sestili
Augusto
A
Division of Cardiology, Santo Spirito Hospital, Lungotevere in Sassia 1, Rome, Italy. sestil@libero.it
Coletta
Claudio
C
Manno
Valerio
V
Perna
Silvia
S
Renzi
Marco
M
Romano
Patrizia
P
Ricci
Roberto
R
Ceci
Vincenzo
V
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D016009:Chi-Square Distribution; D004280:Dobutamine; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011379:Prognosis; D012680:Sensitivity and Specificity
D004280:Dobutamine