Association of Hb Shelby with Hb S in the south of Brazil.
We, herein, report the first observation of compound heterozygosity for hemoglobin Shelby and hemoglobin S identified in the south of Brazil. The variant hemoglobin was identified by isoelectric focusing (IEF), high performance liquid chromatography (HPLC) and DNA sequence analysis.
Wagner
Sandrine Comparsi
SC
Pereira
Cristiane
C
Castro
Simone M
SM
D001938:Brazil; D004247:DNA / Q000097:blood / Q000737:chemistry; D006580:Genetic Carrier Screening; D014644:Genetic Variation; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D017384:Sequence Deletion
D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; C044398:hemoglobin Shelby; D004247:DNA