Episulfonium ion-mediated cyclic peptide and triazine synthesis.
The product of an episulfonium ion-mediated cyclotrimerisation, previously reported as being a 15-membered ring trilactam, has now been shown to be a 1,3,5-triazine. Smaller medium-ring bilactams have, however, been synthesised from linear precursors using the sulfur-based methodology.
Fox
David J
DJ
University Chemical Laboratory, Lensfield Road, Cambridge, UK. djf34@cam.ac.uk
Morley
Thomas J
TJ
Warren
Stuart
S
D010456:Peptides, Cyclic / Q000138:chemical synthesis*; D013452:Sulfonium Compounds / Q000737:chemistry*; D014227:Triazines / Q000138:chemical synthesis*
D010456:Peptides, Cyclic; D013452:Sulfonium Compounds; D014227:Triazines