title: Klippel-Trenaunay syndrome: a multisystem disorder possibly resulting from a pathogenic gene for vascular and tissue overgrowth.
abstract: Klippel-Trenaunay syndrome is characterized by a triad of varicose veins, cutaneous capillary malformation, and hypertrophy of bone and soft tissue. Appropriate evaluation and treatment of children displaying features of the disease may minimize morbidity. The clinical appearance, etiology, genetics, diagnostics, and treatment of Klippel-Trenaunay syndrome are herein explored.
authors.affiliation: Dermatology and Pediatrics, New Jersey Medical School, Newark, NJ 07103-2714, USA.
authors.forename: George G
authors.initials: GG
authors.lastname: Kihiczak
authors.forename: Jon G
authors.initials: JG
authors.lastname: Meine
authors.forename: Robert A
authors.initials: RA
authors.lastname: Schwartz
authors.forename: Camila K
authors.initials: CK
authors.lastname: Janniger
mesh_terms: D042501:Angiogenic Proteins / Q000235:genetics*; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics* / Q000628:therapy
chemical_list: C482200:AGGF1 protein, human; D042501:Angiogenic Proteins