title: Antiphospholipid syndrome: an overview.
abstract: This paper reviews antiphospholipid syndrome (APS), also known as Hughes syndrome, which is a potentially life-threatening autoimmune disorder where the body produces antibodies directed toward phospholipids and phospholipid-binding proteins. Diagnosis of this syndrome relies on both clinical and laboratory criteria. Laboratory testing used for diagnosing APS includes coagulation assays for the detection of lupus anticoagulant (LA) and enzyme-linked immunosorbent assay (ELISA) for antiphospholipid antibody (APL) detection.
authors.affiliation: USAF BSC, Air Force Institute of Technology, Civilian Institution Programs, USA. angieandken@verizon.net
authors.forename: Angelica
authors.initials: A
authors.lastname: Black
mesh_terms: D016736:Antiphospholipid Syndrome / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D015415:Biomarkers; D001780:Blood Coagulation Tests; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D011379:Prognosis
chemical_list: D015415:Biomarkers; D007136:Immunoglobulins