Effects of exercise and nutritional counseling in women with polycystic ovary syndrome.
This pilot study assessed the effects of exercise and nutritional counseling on hormonal, menstrual, and reproductive function in women with polycystic ovary syndrome (PCOS). Twelve females with a clinical, biochemical, and ultrasonographic diagnosis of PCOS were randomly assigned to endurance and resistance exercise plus nutritional counseling (EN) or nutritional counseling only (N) for a period of 12 weeks. Anthropometry, resting metabolic rate (RMR), selected hormones, and ovarian follicle population were measured pre and post-intervention. Following the 12 week intervention, greater decreases in sum of 2 skinfolds (p = 0.002) and a greater increase in estimated VO2 max (p = 0.017) occurred in the exercise group. Significant decreases in waist girth (p = 0.001) and insulin levels (p = 0.03) occurred in both groups. Hormonal changes were not statistically significant; however, a trend towards an improved hormonal profile, specifically sex-hormone binding globulin (EN, 39% increase; N, 8% increase) and lutenizing hormone : follicle-stimulating hormone (LH:FSH) (EN, 9% decrease; N, 27% decrease) occurred in the absence of weight loss. These findings suggest exercise and nutritional counseling may benefit the metabolic and reproductive abnormalities associated with PCOS.
Bruner
Brenda
B
University of Saskatchewan, College of Kinesiology, 87 Campus Drive, Saskatoon, SK S7N 5B2, Canada. brenda.bruner@usask.ca
Chad
Karen
K
Chizen
Donna
D
D000886:Anthropometry; D001481:Basal Metabolism; D015992:Body Mass Index; D003376:Counseling; D015444:Exercise; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D007986:Luteinizing Hormone / Q000097:blood; D009747:Nutritional Physiological Phenomena; D010807:Physical Endurance; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D012885:Skinfold Thickness; D014463:Ultrasonography
D007328:Insulin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone