title: [Activity of acid aspartic proteinase Candida strains isolated from palatine tonsils].
abstract: We have evalueated the activity of acidous asparagine protease in 48 strains of Candida isolated from homogenates of palatine tonsils from 116 patients after tonsilectomy. Strains most frequently isolated were C. albicans (66.7 +/- 6.8%) and C. tropicalis (14.6 +/- 5.09%). The range of proteolysis zone for Candida strains was 4.6 to 12.5 mm. Over 60% of the studied strains showed high and very high proteolytic activity (>6.6 mm) and the remaining strains showed moderate activity (4.6-6.5). There were no strains with low medium activity (to 4.5 mm zone). The range of the number of rosettes E formed by lymphocytes obtained from the studied tonsils was 0-268.3. Lymphocytes isolated from 70 % of tonsils infected with Candida formed only 0-130 rosettes E; in the remaining cases the number ranged between 131 and 220. The number of lymphocytes T forming rosettes E isolated from palatine tonsils from patients not infected with fungi was 2.5 times higher. There was no correlation between the size of proteolysis zone and the number of rosettes E.
authors.affiliation: Katedra Biologii i Parazytologii Lekarskiej AM, 90-436 Lódź, ul. Al. Kościuszki 85.
authors.forename: A
authors.initials: A
authors.lastname: Rózga
authors.forename: A
authors.initials: A
authors.lastname: Jaskółowska
authors.forename: P
authors.initials: P
authors.lastname: Kurnatowski
mesh_terms: D016282:Aspartic Acid Endopeptidases / Q000378:metabolism*; D002175:Candida / Q000201:enzymology* / Q000302:isolation & purification*; D002177:Candidiasis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D014066:Palatine Tonsil / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D014774:Virulence
chemical_list: D016282:Aspartic Acid Endopeptidases