title: Uveal metastases from breast carcinoma in three male patients.
abstract: The authors present a case series of three male patients with uveal metastases originating from breast carcinoma. The mean age at discovery of uveal metastases and the mean interval from diagnosis of primary breast carcinoma were 49.7 and 2.3 years, respectively. The analogous data in women are 56 and 5.4 years, respectively. In this series, all three patients were affected bilaterally and four of six eyes (67%) had multifocal tumors. In women, metastases are bilateral in 38% and multifocal in 48%. Compared with women, metastases in men may occur sooner and with a higher incidence of bilateral and multifocal tumors.
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Lam
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D001918:Brachytherapy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D018567:Breast Neoplasms, Male / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D008297:Male; D015409:Mastectomy, Radical; D008875:Middle Aged; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents