title: [A case of tuberculous lymphadenitis found as an abdominal mass penetrating the duodenum].
abstract: A 42-year-old woman who complained of epigastralgia was referred to our hospital because of an abdominal mass found by ultrasonography. CT and MRI scans revealed that the abdominal mass, 4 cm in diameter, located on the left side of the right kidney. Gastroduodenoscopy detected a deep ulcerative lesion covered with a yellowish coat in the second portion of duodenum. A sonolucent area at the bottom of the ulcerative lesion seemed to expand to the abdominal mass on ultrasonic endoscopy. Tuberculosis was one possible differential diagnosis. Pathological examination including Ziehl-Neelsen staining using biopsy specimens taken from the bottom of the ulcerative lesion did not show tuberculosis infection. However, polymerase chain reaction analysis using the biopsy specimens revealed that gene expression of tuberculosis was positive. We determined that tuberculous lymphadenitis penetrated the duodenum forming an ulcerative lesion in the duodenum. The administration of anti-tubercular medicine for 6 months male the abdominal mass disappeared and the duodenal ulcerative lesion formed an ulcer scar. We report here a case of tuberculous lymphadenitis penetrating the duodenum which was successfully treated by conservative therapy without surgical treatment.
authors.affiliation: Department of Gastroenterology, Tokai University School of Medicine.
authors.forename: Kayoko
authors.initials: K
authors.lastname: Tokiwa
authors.forename: Shigenari
authors.initials: S
authors.lastname: Hozawa
authors.forename: Seiichirou
authors.initials: S
authors.lastname: Kojima
authors.forename: Keinji
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Watanabe
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mine
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kijima
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imai
authors.forename: Hayato
authors.initials: H
authors.lastname: Miyachi
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006801:Humans; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000995:Antitubercular Agents