[Characteristics of metastasis and recurrence following curative resection for colonic carcinoma].
OBJECTIVE
To investigate the characteristics of metastasis and recurrence following curative resection for colonic carcinoma,and analyze the prognosis.


METHODS
The clinicopathological and follow-up data of 310 patients with colon carcinoma undergoing curative resection were analyzed retrospectively.


RESULTS
The recurrence rate after curative resection was 23.2% (72/310). The 5-year survival rate was 64.6%. Hepatic metastasis accounted for 38.9% of the cases. Gross classification,histological type, differentiation, lymph node metastasis were correlated with metastasis/recurrence. Univariate analysis revealed that gross classification, histological type, differentiation, lymph node metastasis, blood vessel invasion, TNM Stage, postoperative chemotherapy, portal chemotherapy were prognostic factors. Cox regression analysis revealed that only gross classification, lymph node metastasis, postoperative chemotherapy, portal chemotherapy were independent prognostic factors.


CONCLUSIONS
Liver is the most common metastatic site after curative resection for colonic carcinoma. Gross classification, lymph node metastasis, postoperative chemotherapy, and portal chemotherapy are independent prognostic factors.
Zhao
Dong-bing
DB
Department of Abdominal Surgery, Cancer Hospital Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. dbzhao2003@sina.com
Gao
Ji-dong
JD
Shan
Yi
Y
Zhou
Zhi-xiang
ZX
Yuan
Xing-hua
XH
Wu
Jian-xiong
JX
Shao
Yong-fu
YF
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D009367:Neoplasm Staging; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies