title: [Retinal changes in patients with familial adenomatous polyposis].
abstract: OBJECTIVE
  The aim of study was to evaluate retinal changes in patients diagnosed with familial adenomatous polyposis (FAP) and in patients with family history of FAP.
  
  
  METHODS
  The study was conducted on 51 patients diagnosed with FAP and 35 subjects with family history of FAP.
  
  
  RESULTS
  In 44 patients diagnosed with FAP (86.2%), typical pigmentation of fundus lesions were observed, in 1 patient atypical fundus changes were evident. However, in the group of patients with family history of FAP, the presence of typical fundus lesions was observed in 9 patients (25.7%). In the period of at least 6 month observation, no changes in fundus lesions were present in both groups.
  
  
  CONCLUSIONS
  The occurrence of retinal changes typical for FAP, especially in patients with family history of the disease, should imply the higher risk of FAP.
authors.affiliation: Katedry i Kliniki Okulistyki Akademii Medycznej w Poznaniu.
authors.forename: Elibieta
authors.initials: E
authors.lastname: Cymerys
authors.forename: Krystyna
authors.initials: K
authors.lastname: Pecold
authors.forename: Jacek
authors.initials: J
authors.lastname: Paszkowski
authors.forename: Tomasz
authors.initials: T
authors.lastname: Banasiewicz
authors.forename: Piotr
authors.initials: P
authors.lastname: Krokowicz
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000235:genetics*; D012171:Retinal Vessels / Q000473:pathology