title: Otogenic skull base osteomyelitis caused by invasive fungal infection. Case report and literature review.
abstract: Otogenic skull base osteomyelitis (SBO) of fungal etiology is a very rare but life-threatening complication of inflammatory processes of the ear. The authors present a case of otogenic SBO caused by Aspergillus flavus in a 65-year-old man with a fatal course. Because of the encountered difficulties with the proper diagnosis and treatment, the authors reviewed the literature on the subject.
authors.affiliation: Department of Otolaryngology, Medical University of Gdańsk, ul. Debinki 7, 80211 Gdańsk, Poland. dstodulski@amg.gda.pl
authors.forename: Dominik
authors.initials: D
authors.lastname: Stodulski
authors.forename: Bozena
authors.initials: B
authors.lastname: Kowalska
authors.forename: Czesław
authors.initials: C
authors.lastname: Stankiewicz
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002426:Cavernous Sinus / Q000382:microbiology / Q000473:pathology; D002558:Cerebrospinal Fluid Otorrhea / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D020953:Neuroaspergillosis / Q000150:complications* / Q000188:drug therapy; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D019152:Paracentesis; D019291:Skull Base / Q000382:microbiology* / Q000473:pathology*
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B