title: Impact of laboratory cross-contamination on molecular epidemiology studies of tuberculosis.
abstract: Laboratory cross-contamination by Mycobacterium tuberculosis is known to be responsible for the misdiagnosis of tuberculosis, but its impact on other contexts has not been analyzed. We present the findings of a molecular epidemiology analysis in which the recent transmission events identified by a genotyping reference center were overestimated as a result of unnoticed laboratory cross-contamination in the original diagnostic laboratories.
authors.affiliation: Complejo Hospitalario Torrecárdenas, Almería, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Martínez
authors.forename: Darío
authors.initials: D
authors.lastname: García de Viedma
authors.forename: María
authors.initials: M
authors.lastname: Alonso
authors.forename: Sandra
authors.initials: S
authors.lastname: Andrés
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
authors.forename: Teresa
authors.initials: T
authors.lastname: Cabezas
authors.forename: Isabel
authors.initials: I
authors.lastname: Cabeza
authors.forename: Armando
authors.initials: A
authors.lastname: Reyes
authors.forename: Waldo
authors.initials: W
authors.lastname: Sánchez-Yebra
authors.forename: Manuel
authors.initials: M
authors.lastname: Rodríguez
authors.forename: M Isabel
authors.initials: MI
authors.lastname: Sánchez
authors.forename: M Cruz
authors.initials: MC
authors.lastname: Rogado
authors.forename: Rosa
authors.initials: R
authors.lastname: Fernández
authors.forename: Teresa
authors.initials: T
authors.lastname: Peñafiel
authors.forename: Juan
authors.initials: J
authors.lastname: Martínez
authors.forename: Pilar
authors.initials: P
authors.lastname: Barroso
authors.forename: M Angeles
authors.initials: MA
authors.lastname: Lucerna
authors.forename: L Felipe
authors.initials: LF
authors.lastname: Diez
authors.forename: Carmelo
authors.initials: C
authors.lastname: Gutiérrez
mesh_terms: D015373:Bacterial Typing Techniques; D003951:Diagnostic Errors; D004866:Equipment Contamination; D006801:Humans; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification*; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology*