Catalysis and rational engineering of trans-acting pH6DZ1, an RNA-cleaving and fluorescence-signaling deoxyribozyme with a four-way junction structure.
Shen
Yutu
Y
Department of Chemistry, McMaster University, 1280 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
Chiuman
William
W
Brennan
John D
JD
Li
Yingfu
Y
D000249:Adenosine Monophosphate / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry / Q000494:pharmacology; D000494:Allosteric Regulation; D001483:Base Sequence; D002384:Catalysis / Q000187:drug effects; D021881:DNA, Catalytic / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D019793:Fluorescein / Q000737:chemistry*; D005453:Fluorescence; D007700:Kinetics; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation / Q000187:drug effects; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D004124:p-Dimethylaminoazobenzene / Q000031:analogs & derivatives / Q000737:chemistry
D021881:DNA, Catalytic; D000249:Adenosine Monophosphate; C063127:4-(4-dimethylaminophenylazo)benzoic acid; D012313:RNA; D000255:Adenosine Triphosphate; D004124:p-Dimethylaminoazobenzene; D019793:Fluorescein