title: Recent advances in capillary electrophoretic analysis of individual cells.
abstract: Because variability exists within populations of cells, single-cell analysis has become increasingly important for probing complex cellular environments. Capillary electrophoresis (CE) is an excellent technique for identifying and quantifying the contents of single cells owing to its small volume requirements and fast, efficient separations with highly sensitive detection. Recent progress in both whole-cell and subcellular sampling has allowed researchers to study cellular function in the areas of neuroscience, oncology, enzymology, immunology, and gene expression.
authors.affiliation: Department of Chemistry, Pennsylvania State University, University Park, PA, USA.
authors.forename: Imee G
authors.initials: IG
authors.lastname: Arcibal
authors.forename: Michael F
authors.initials: MF
authors.lastname: Santillo
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Ewing
mesh_terms: D000818:Animals; D019075:Electrophoresis, Capillary / Q000379:methods* / Q000639:trends; D004798:Enzymes / Q000032:analysis / Q000378:metabolism; D005057:Eukaryotic Cells / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D007158:Immunologic Techniques; D008495:Medical Oncology / Q000379:methods; D009488:Neurosciences / Q000379:methods; D012333:RNA, Messenger / Q000032:analysis; D013347:Subcellular Fractions / Q000737:chemistry
chemical_list: D004798:Enzymes; D012333:RNA, Messenger