title: Spironolactone with ACE inhibitor is effective in gross hematuria caused by nephroptosis.
abstract: Gross hematuria caused by nephroptosis is difficult to treat and sometimes requires surgical treatment. We experienced a case of a 64-year-old woman with gross hematuria due to nephroptosis and glomerular thin basement membrane that showed remission of hematuria with the blockade of the renin-angiotensin-aldosterone system with an angiotensin-converting enzyme inhibitor and spironolactone.
authors.affiliation: Division of Nephrology and Endocrinology, Department of Internal Medicine, University of Tokyo, Japan. tojyo-2im@h.u-tokyo.ac.jp
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tojo
authors.forename: Maristela Lika
authors.initials: ML
authors.lastname: Onozato
authors.forename: Kensuke
authors.initials: K
authors.lastname: Asaba
authors.forename: Toshiro
authors.initials: T
authors.lastname: Fujita
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006417:Hematuria / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use*; D013148:Spironolactone / Q000627:therapeutic use*
chemical_list: D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone