Primary intracranial leiomyoma: a case report and literature review.
We report a case of primary intracranial leiomyoma in 29-year-old woman presented with severe headache. The radiology diagnosis was consistent with meningioma. However, histologically, the tumor had the characteristic appearance of benign smooth muscle. This was confirmed by immunohistochemistry and electron microscopy. Benign metastasizing leiomyoma was excluded by thorough imaging. Although rare, leiomyoma should be considered in the differential diagnosis of well-circumscribed intracranial lesion.
Ali
Abdullah E
AE
Department of Pathology, Sunnybrook Health Science Centre, 2075 Bayview Avenue, Room E-419, Toronto, ON, M4N 3M5, Canada. Juan.Bilbao@sunnybrook.ca
Fazl
Mahmood
M
Bilbao
Juan M
JM
D000328:Adult; D014408:Biomarkers, Tumor; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D002148:Calmodulin-Binding Proteins / Q000032:analysis; D022162:Cytoplasmic Vesicles / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007382:Intermediate Filaments / Q000648:ultrastructure; D007889:Leiomyoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging
D014408:Biomarkers, Tumor; D002148:Calmodulin-Binding Proteins