title: Small-cell lung carcinoma of recipient origin after bilateral lung transplantation for cystic fibrosis.
abstract: Bronchial carcinoma, usually of the non-small-cell type, is uncommon after lung transplantation and occurs predominantly in single-lung transplant ex-smoker recipients on their native lung. Bronchial carcinoma of donor origin is much rarer. We report the case of a small-cell lung carcinoma of recipient origin that occurred 12 months after a bilateral lung transplantation for cystic fibrosis in a 25-year-old woman who was a non-smoker. The tumor was of recipient origin, due to a gender mismatch between donor and recipient. This unusual observation corroborates the hypothesis of chimerism of the bronchial epithelium after lung transplantation.
authors.affiliation: Service pneumologie, Hôpital Foch, Suresnes, France.
authors.forename: Clément
authors.initials: C
authors.lastname: Picard
authors.forename: Dominique
authors.initials: D
authors.lastname: Grenet
authors.forename: Christiane
authors.initials: C
authors.lastname: Copie-Bergman
authors.forename: Nadine
authors.initials: N
authors.lastname: Martin
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Longchampt
authors.forename: Leila
authors.initials: L
authors.lastname: Zemoura
authors.forename: Marc
authors.initials: M
authors.lastname: Stern
mesh_terms: D000328:Adult; D018288:Carcinoma, Small Cell / Q000209:etiology* / Q000473:pathology; D003550:Cystic Fibrosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology; D016040:Lung Transplantation / Q000009:adverse effects*