[A case of liver cysts with Em18-WB was useful for differential diagnosis].
A 72-year-old woman with multilocular liver cysts was admitted. This lesions seemed to be an alveolar hydatid disease. Two methods of Western blotting were used for serologic diagnosis. One method recognizes antigens of crude extracts of Echinococcus multilocularis (EM). The other method recognizes a purified antigen (Em18) of EM. Her serum only reacted with the former method and never reacted with Em18 antigen. Eighteen months after first admission, she had an operation. The resected specimen was diagnosed with simple cysts. Western blotting using Em18 antigen could greatly facilitate the differential diagnosis of simple liver cyst and alveolar hydatid disease.
Aoki
Takanori
T
Second Department of Surgery, Asahikawa Medical College.
Kino
Shuichi
S
Yamazaki
Hirotaka
H
Obara
Mitsuhiro
M
Kasai
Shinichi
S
Yamasaki
Hiroshi
H
Ito
Akira
A
D000368:Aged; D000947:Antigens, Helminth / Q000032:analysis*; D003560:Cysts / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000175:diagnosis; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*
D000947:Antigens, Helminth; C117889:Em18 antigen