title: CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea.
abstract: In a nested-case control study of 100 cases of gastric cancer and 400 matched controls in relation to virulence factors of Helicobacter pylori in a Korean cohort, CagA seropositivity was significantly associated with a higher risk of gastric cancer among H. pylori-infected subjects (OR=3.57, 95% CI 1.05-12.14).
authors.affiliation: Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-799, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Gwack
authors.forename: A
authors.initials: A
authors.lastname: Shin
authors.forename: C-S
authors.initials: CS
authors.lastname: Kim
authors.forename: K-P
authors.initials: KP
authors.lastname: Ko
authors.forename: Y
authors.initials: Y
authors.lastname: Kim
authors.forename: J K
authors.initials: JK
authors.lastname: Jun
authors.forename: J
authors.initials: J
authors.lastname: Bae
authors.forename: S K
authors.initials: SK
authors.lastname: Park
authors.forename: Y-C
authors.initials: YC
authors.lastname: Hong
authors.forename: D
authors.initials: D
authors.lastname: Kang
authors.forename: S-H
authors.initials: SH
authors.lastname: Chang
authors.forename: H-R
authors.initials: HR
authors.lastname: Shin
authors.forename: K-Y
authors.initials: KY
authors.lastname: Yoo
mesh_terms: D000368:Aged; D000428:Alcohol Drinking; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D016022:Case-Control Studies; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000453:epidemiology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000382:microbiology*; D014774:Virulence
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C080866:cagA protein, Helicobacter pylori