title: Surface treatments of titanium dental implants for rapid osseointegration.
abstract: The osseointegration rate of titanium dental implants is related to their composition and surface roughness. Rough-surfaced implants favor both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. The different methods used for increasing surface roughness or applying osteoconductive coatings to titanium dental implants are reviewed. Surface treatments, such as titanium plasma-spraying, grit-blasting, acid-etching, anodization or calcium phosphate coatings, and their corresponding surface morphologies and properties are described. Most of these surfaces are commercially available and have proven clinical efficacy (>95% over 5 years). The precise role of surface chemistry and topography on the early events in dental implant osseointegration remain poorly understood. In addition, comparative clinical studies with different implant surfaces are rarely performed. The future of dental implantology should aim to develop surfaces with controlled and standardized topography or chemistry. This approach will be the only way to understand the interactions between proteins, cells and tissues, and implant surfaces. The local release of bone stimulating or resorptive drugs in the peri-implant region may also respond to difficult clinical situations with poor bone quality and quantity. These therapeutic strategies should ultimately enhance the osseointegration process of dental implants for their immediate loading and long-term success.
authors.affiliation: Inserm U791, LIOAD, Osteoarticular and Dental Tissue Engineering, Faculty of Dental Surgery, 1 Place Alexis Ricordeau, 44042 Nantes cedex 1, France.
authors.forename: L
authors.initials: L
authors.lastname: Le Guéhennec
authors.forename: A
authors.initials: A
authors.lastname: Soueidan
authors.forename: P
authors.initials: P
authors.lastname: Layrolle
authors.forename: Y
authors.initials: Y
authors.lastname: Amouriq
mesh_terms: D040761:Biomimetic Materials; D019485:Bone Morphogenetic Proteins; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D045662:Dental Etching; D015921:Dental Implants; D049329:Nanostructures; D016348:Osseointegration; D013499:Surface Properties; D014025:Titanium
chemical_list: D019485:Bone Morphogenetic Proteins; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; C020243:calcium phosphate; D014025:Titanium