Probing enzyme phosphoester interactions by combining mutagenesis and chemical modification of phosphate ester oxygens.
Stivers
James T
JT
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA. jstivers@jhmi.edu
Nagarajan
Rajesh
R
D004798:Enzymes / Q000737:chemistry* / Q000235:genetics; D006860:Hydrogen Bonding; D008968:Molecular Conformation; D016296:Mutagenesis; D010755:Organophosphates / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D013379:Substrate Specificity
D004798:Enzymes; D010755:Organophosphates; D010100:Oxygen