title: Revisiting nucleophilic substitution reactions: microwave-assisted synthesis of azides, thiocyanates, and sulfones in an aqueous medium.
abstract: A practical, rapid, and efficient microwave (MW) promoted synthesis of various azides, thiocyanates, and sulfones is described in an aqueous medium. This general and expeditious MW-enhanced nucleophilic substitution approach uses easily accessible starting materials such as halides or tosylates in reaction with alkali azides, thiocyanates, or sulfinates in the absence of any phase-transfer catalyst, and a variety of reactive functional groups are tolerated.
authors.affiliation: Clean Processes Branch, Sustainable Technology Division, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA.
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Ju
authors.forename: Dalip
authors.initials: D
authors.lastname: Kumar
authors.forename: Rajender S
authors.initials: RS
authors.lastname: Varma