Evaluation of adhesive properties of Candida albicans isolated from the oral cavity in HIV positive patients.
The aim of the work was to compare adhesive properties of Candida albicans strains isolated from the oral cavity in HIV+ vs. HIV- persons. The materials were Candida albicans strains and buccal epithelial cells isolated from both HIV+ and HIV- persons. We applied the in vitro adherence test, primarily described by Kimura and Pearsall and modified by Macura. The strongest adherence was found between both fungi and epithelial cells isolated from a HIV+ person. The adherence of C. albicans isolated from HIV+ patients was significantly stronger to epithelium collected from HIV+ than HIV- persons.
Macura
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Zakład Mykologii Katedry Mikrobiologii Collegium Medicum U.J, 31-121 Kraków, ul. Czysta 18.
Bort
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D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000293:Adolescent; D000328:Adult; D002176:Candida albicans / Q000302:isolation & purification / Q000472:pathogenicity / Q000502:physiology*; D002180:Candidiasis, Oral / Q000382:microbiology* / Q000503:physiopathology*; D002448:Cell Adhesion / Q000502:physiology*; D002478:Cells, Cultured / Q000378:metabolism / Q000382:microbiology; D004848:Epithelium / Q000378:metabolism / Q000382:microbiology; D005260:Female; D018023:HIV Seronegativity / Q000502:physiology; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000382:microbiology*