[Pathophysiology of irritable bowel syndrome].
Irritable bowel syndrome (IBS) is considered a biopsychosocial disorder resulting from a combination of 3 interacting mechanisms: psychosocial factors, altered motility and transit, which may reflect severity of bowel dysfunction, and increased sensitivity of the intestine or colon. In other words, mechanism in IBS is biopsychosocial disorders; psychosocial factors, altered motility, and heightened sensory function. Understanding the brain-gut axis is the key to the eventual development of effective therapies for IBS.
Torii
Akira
A
Department of Internal Medicine, The Jikei University School of Medicine.
D001921:Brain / Q000502:physiology; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000503:physiopathology*; D011584:Psychology