title: Reproductive outcome in patients treated by oral methotrexate or laparoscopic salpingotomy for the management of tubal ectopic pregnancy.
abstract: OBJECTIVE
  To determine the reproductive outcome of women who have received methotrexate or been treated by laparoscopic salpingotomy (LS) for ectopic tubal pregnancy.
  
  
  METHODS
  The study consisted of 123 participants, all women with tubal pregnancies, who had been treated either by methotrexate per os or by laparoscopic salpingotomy. The reproductive outcome of these women was estimated after a follow-up time-period of ten years.
  
  
  RESULTS
  In the methotrexate group, consisting of 34 women, the fertility rate was 82% with a mean interval time to conceive of 9.4 months after the treatment. In the group treated by LS, consisting of 89 women, the fertility rate was 82.6% and the mean interval time to conceive was 11.7 months.
  
  
  CONCLUSIONS
  The reproductive outcome of the women who received either per os treatment of methotrexate or LS for tubal pregnancy, remains high. Both therapeutic methods constitute reliable solutions for managing ectopic pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Endoscopy Unit, Medical School, University of Ioannina, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Dalkalitsis
authors.forename: T
authors.initials: T
authors.lastname: Stefos
authors.forename: A
authors.initials: A
authors.lastname: Kaponis
authors.forename: G
authors.initials: G
authors.lastname: Tsanadis
authors.forename: M
authors.initials: M
authors.lastname: Paschopoulos
authors.forename: V
authors.initials: V
authors.lastname: Dousias
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000284:Administration, Oral; D000328:Adult; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy; D008727:Methotrexate / Q000627:therapeutic use*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D011271:Pregnancy, Ectopic / Q000628:therapy*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate