title: Mammographically detected breast arterial calcifications: indicators for arteriosclerotic diseases?
abstract: OBJECTIVE
  To determine the prevalence of breast arterial calcifications (BAC) detected on mammography and search for conditions that may influence their existence.
  
  
  METHODS
  The mammograms of 6156 consecutive patients were reevaluated for the presence of BAC. Four hundred eighty-five women having BAC were enrolled in the patient group. Additionally, randomly selected 500 women, without BAC constituted the control group. Hospital records of the participants were reviewed for parity, menopausal status, oral contraceptive agent (OCA) usage, hormone replacement therapy (HRT) usage, presence of diabetes, hypertension, hyperlipidemia, albuminuria and history of myocardial infarction (MI).
  
  
  RESULTS
  Prevalence of BAC was 7.9% on mammograms. Ninety-four women were aged between 40 and 49 years, 165 were aged between 50 and 59 years and 226 were over 60 years among BAC positive 485 women. A significant relationship was found for the frequency of BAC versus age and HRT usage in all age groups (p<0.05). Similarly, significant relationships were also found for the frequency of BAC versus OCA usage, HRT usage, hyperlipidemia and diabetes in age group of 40-49 and in age group of 50-59, and for the frequency of BAC versus albuminuria in age group of 40-49, BAC versus history of myocardial infarction in age group of 59-59 and over 60 years (p<0.05). The correlations were not significant for the relationships of BAC with OCA usage, hyperlipidemia, diabetes and albuminuria in women over 60 years (p>0.05).
  
  
  CONCLUSIONS
  Most benign findings like BAC are not routinely reported during mammographic evaluation. Our study showed that, presence of BAC on mammography was strongly related to advancing age. However, these findings may signify a systemic risk and can be used as precautious indicators for undocumented systemic diseases, especially in premenopausal women.
authors.affiliation: Adnan Menderes University, Faculty of Medicine, Department of Radiology, 09100 Aydin, Turkey. fusuntaskin@yahoo.com
authors.forename: Füsun
authors.initials: F
authors.lastname: Taşkin
authors.forename: Alev
authors.initials: A
authors.lastname: Akdilli
authors.forename: Can
authors.initials: C
authors.lastname: Karaman
authors.forename: Alparslan
authors.initials: A
authors.lastname: Unsal
authors.forename: Kutsi
authors.initials: K
authors.lastname: Köseoğlu
authors.forename: Filiz
authors.initials: F
authors.lastname: Ergin
mesh_terms: D000328:Adult; D017677:Age Distribution; D000419:Albuminuria / Q000150:complications; D000704:Analysis of Variance; D001161:Arteriosclerosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology*; D001941:Breast Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology*; D002114:Calcinosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology*; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000009:adverse effects; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000000981:diagnostic imaging; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D008327:Mammography; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D017698:Postmenopause; D017697:Premenopause; D015995:Prevalence; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
chemical_list: D003276:Contraceptives, Oral