title: [Surgical treatment of submacular hemorrhage combined with tissue plasminogen activator (a case report)].
abstract: Authors present the possibilities of extensive submacular hemorrhage surgery in a patient after serious eye injury with bleeding into the vitreous and underneath the retina. The combination of vitrectomy with tissue plasminogen activator application into the subretinal space allows better to dissolve the coagulated blood and facilitates its removal. This procedure with correct operation technique decreases the damage of the retinal tissue and consequently preserves the photoreceptors' function. In this report, a result of surgical treatment in a 22-year-old man is presented. In the presence of intravitreal bleeding and submacular hemorrhage, during the vitrectomy the tissue plasminogen activator was used, which during few minutes dissolved the already coagulated hemorrhage and facilitated its whole removal from the subretinal space.
authors.affiliation: Ocní klinika FN, Hradec Králové. kordav@lfhk.cuni.cz
authors.forename: V
authors.initials: V
authors.lastname: Korda
authors.forename: Z
authors.initials: Z
authors.lastname: Dúbravská
authors.forename: D
authors.initials: D
authors.lastname: Hejcmanová
authors.forename: P
authors.initials: P
authors.lastname: Rozsíval
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D015807:Eye Injuries, Penetrating / Q000150:complications*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D012166:Retinal Hemorrhage / Q000188:drug therapy / Q000601:surgery*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014821:Vitrectomy
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator