Concepts in molecular dermatotoxicology.
In the recent years, molecular research has successfully elucidated some of the major mechanisms through which environmental noxae damage human skin. From this knowledge, novel concepts for skin protection have been developed. Here, we provide a brief overview of some of the most exciting and intriguing concepts in molecular dermatotoxicology.
Merk
Hans F
HF
Department of Dermatology and Allergology, RWTH Aachen, Aachen, Germany. Hans.Merk@post.rwth-aachen.de
Baron
Jens M
JM
Heise
Ruth
R
Fritsche
Ellen
E
Schroeder
Peter
P
Abel
Josef
J
Krutmann
Jean
J
D002462:Cell Membrane / Q000528:radiation effects; D004249:DNA Damage / Q000528:radiation effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D003885:Dermotoxins / Q000494:pharmacology; D004342:Drug Hypersensitivity / Q000209:etiology; D006801:Humans; D007259:Infrared Rays; D008563:Membrane Lipids / Q000528:radiation effects; D010655:Phenylenediamines / Q000494:pharmacology; D012867:Skin / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology; D014466:Ultraviolet Rays
D003885:Dermotoxins; D008563:Membrane Lipids; D010655:Phenylenediamines; C029728:4-phenylenediamine