title: Occipital condyle syndrome guiding diagnosis to metastatic prostate cancer.
abstract: Occipital condyle syndrome (OCS) results from a unilateral occipital pain associated with an ipsilateral paresis of the 12th cranial nerve (hypoglossal), and is typically caused by metastasis of the skull base. OCS diagnosis occurred, in all cases described in the published literature, when metastatic prostate cancer (MPC) was previously known. We present a case of a patient whose initial manifestation of MPC was OCS. The patient was treated with complete hormonal blockade and non-steroidal anti-inflammatory drugs as opposed to locoregional radiotherapy applied in other cases. After 18 month follow-up, the patient had a complete neurological and biochemical response.
authors.affiliation: Department of Urology, Hospiatal Gregorio Maranon, Madrid, Spain. msalam99@terra.es
authors.forename: Juan Ignacio Martinez
authors.initials: JI
authors.lastname: Salamanca
authors.forename: Concepcion
authors.initials: C
authors.lastname: Murrieta
authors.forename: Jose
authors.initials: J
authors.lastname: Jara
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Munoz-Blanco
authors.forename: Federico
authors.initials: F
authors.lastname: Alvarez
authors.forename: Juan Guzman
authors.initials: JG
authors.lastname: De Villoria
authors.forename: Carlos
authors.initials: C
authors.lastname: Hernandez
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D019160:Endosonography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009777:Occipital Bone; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013577:Syndrome; D014057:Tomography, X-Ray Computed