UniPep--a database for human N-linked glycosites: a resource for biomarker discovery.
There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery.
Zhang
Hui
H
Institute for Systems Biology, Seattle, WA 98103, USA. hzhang@systemsbiology.org
Loriaux
Paul
P
Eng
Jimmy
J
Campbell
David
D
Keller
Andrew
A
Moss
Pat
P
Bonneau
Richard
R
Zhang
Ning
N
Zhou
Yong
Y
Wollscheid
Bernd
B
Cooke
Kelly
K
Yi
Eugene C
EC
Lee
Hookeun
H
Peskind
Elaine R
ER
Zhang
Jing
J
Smith
Richard D
RD
Aebersold
Ruedi
R
D019295:Computational Biology / Q000379:methods; D030541:Databases, Genetic; D005819:Genetic Markers / Q000235:genetics*; D006020:Glycopeptides / Q000097:blood* / Q000138:chemical synthesis* / Q000235:genetics*; D006801:Humans; D013058:Mass Spectrometry
D005819:Genetic Markers; D006020:Glycopeptides