Overview of vaccine field studies: types of effects and designs.
Vaccination produces many different types of effects in individuals and in populations. The scientific and public health questions of interest determine the choice of measures of effect and study designs. Here we review some of the various measures and study designs for evaluating different effects of vaccination.
Halloran
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Program in Biostatistics and Biomathematics, Public Health Sciences, Fred Hutchinson Cancer Research Center, Department of Biostatistics, University of Washington, Seattle, USA. betz@u.washington.edu
D000818:Animals; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000706:statistics & numerical data; D012107:Research Design / Q000706:statistics & numerical data; D014611:Vaccination / Q000379:methods* / Q000706:statistics & numerical data; D014612:Vaccines / Q000009:adverse effects / Q000627:therapeutic use*
D014612:Vaccines