title: Preload independence of isovolumic relaxation flow propagation velocity.
abstract: To evaluate whether isovolumic relaxation flow propagation velocity (IRFPV) is independent of preload alterations, 41 healthy subjects (35 +/- 7 years) were included for Doppler examinations at three different positions, i.e., supine, Trendelenburg, and reverse Trendelenburg. A positional difference was detected in the peak velocity of the transmitral early diastolic flow wave (P = 0.012) and the peak velocities of both early (P = 0.004) and late (P = 0.007) diastolic mitral annular velocity waves. In contrast, there was no positional difference in the early diastolic inflow propagation velocity or IRFPV. In conclusion, IRFPV is a preload-independent Doppler parameter.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. wcvoon@giga.net.tw
authors.forename: Wen-Chol
authors.initials: WC
authors.lastname: Voon
authors.forename: Ho-Ming
authors.initials: HM
authors.lastname: Su
authors.forename: Hsueh-Wei
authors.initials: HW
authors.lastname: Yen
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Lin
authors.forename: Wen-Ter
authors.initials: WT
authors.lastname: Lai
authors.forename: Sheng-Hsiung
authors.initials: SH
authors.lastname: Sheu
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D003971:Diastole / Q000502:physiology; D018618:Echocardiography, Doppler, Color; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D011187:Posture / Q000502:physiology; D012016:Reference Values; D016276:Ventricular Function