Nuclear import of spliceosomal snRNPs.
Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are the building units of the spliceosome. These RNA and protein complexes assemble in the cytoplasm. After proper assembly and RNA maturation, mature U snRNPs are imported into the cell nucleus, where they take part in the splicing process. In this paper we review the current knowledge of how U snRNPs enter the nucleus.
Rollenhagen
Christiane
C
Department of Zoology, University of British Columbia, Vancouver, Canada.
Panté
Nelly
N
D021581:Active Transport, Cell Nucleus; D000818:Animals; D006151:Guanosine / Q000031:analogs & derivatives* / Q000378:metabolism; D008854:Microscopy, Electron; D019913:Nuclear Localization Signals / Q000378:metabolism; D022022:Nuclear Pore / Q000378:metabolism; D009865:Oocytes / Q000378:metabolism; D017411:Ribonucleoproteins, Small Nuclear / Q000378:metabolism*; D014981:Xenopus
D019913:Nuclear Localization Signals; D017411:Ribonucleoproteins, Small Nuclear; D006151:Guanosine; C017778:N(2),N(2),7-trimethylguanosine