Palladium-catalyzed C-H homocoupling of bromothiophene derivatives and synthetic application to well-defined oligothiophenes.
Synthesis of oligothiophenes of well-defined structures that possess 2-8 thiophene units is performed with a new synthetic strategy involving C-H homocoupling of bromothiophenes and cross-coupling with organostannanes. Tolerance of the carbon-bromine bond to the palladium-catalyzed C-H homocoupling results in oligothiophenes bearing C-Br bonds at the terminal thiophene rings, which allow further transformation by the catalysis of a transition-metal complex.
Takahashi
Masabumi
M
Chemical Resources Laboratory, Tokyo Institute of Technology, R1-4 4259 Nagatsuta, Yokohama 226-8503, Japan.
Masui
Kentaro
K
Sekiguchi
Hiroki
H
Kobayashi
Nobuhiko
N
Mori
Atsunori
A
Funahashi
Masahiro
M
Tamaoki
Nobuyuki
N