title: Humoral response in hamsters following vaccination with cDNA encoding acey-1 cysteine proteinase of Ancylostoma ceylanicum.
abstract: The humoral response in hamsters following vaccination against Ancylostoma ceylanicum infections with DNA construct was investigated. Groups of hamsters were injected intramuscularly with plasmid pcDNA 3.1. containing cDNA of ACEY-1 cysteine proteinase. Vaccination resulted in IgG antibody response to somatic extracts of adult A. ceylanicum. The highest level of antibodies was observed seven weeks after vaccination.
authors.affiliation: Parasitology Department, Warsaw Agricultural University, 03-849 Warszawa, Grochowska 272.
authors.forename: J
authors.initials: J
authors.lastname: Mieszczanek
authors.forename: M
authors.initials: M
authors.lastname: Swiderska
authors.forename: H
authors.initials: H
authors.lastname: Wedrychowicz
mesh_terms: D000722:Ancylostoma / Q000201:enzymology*; D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000917:Antibody Formation / Q000187:drug effects*; D000947:Antigens, Helminth / Q000302:isolation & purification; D006224:Cricetinae; D003546:Cysteine Endopeptidases / Q000008:administration & dosage* / Q000235:genetics / Q000276:immunology; D018076:DNA, Complementary / Q000008:administration & dosage*; D018509:DNA, Helminth / Q000008:administration & dosage*; D007114:Immunization / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood; D019444:Vaccines, DNA / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D018076:DNA, Complementary; D018509:DNA, Helminth; D007074:Immunoglobulin G; D019444:Vaccines, DNA; D003546:Cysteine Endopeptidases