Gastroesophageal reflux disease in Asian countries: disorder of nature or nurture?
Gastroesophageal reflux disease (GERD) is less prevalent in Asia than in the West, but there is now evidence to suggest that its frequency is rapidly rising in Asia. The different prevalence rates reported in various Asian studies may represent different points in the 'rising' phase of GERD. The cause for the lower but increasing prevalence of GERD in Asia is not known, but genetics and to some extent environmental factors, may have initially protected Asians against GERD. However, with the recent globalization of economies, the associated lifestyle changes in many developing Asian countries may have tipped the balance in favor of the development of GERD.
Ho
Khek Yu
KY
Department of Medicine, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. mdchoky@nus.edu.sg
Cheung
Ting Kin
TK
Wong
Benjamin Cy
BC
D001208:Asia / Q000453:epidemiology; D004041:Dietary Fats; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D016480:Helicobacter pylori; D006801:Humans; D009765:Obesity; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology; D014481:United States / Q000453:epidemiology
D004041:Dietary Fats