title: Use of the Amplatzer vascular plug as an anchoring scaffold for coil-mediated parent vessel occlusion: technical case report.
abstract: OBJECTIVE
  Parent vessel sacrifice is a useful treatment strategy for fusiform intracranial aneurysms. Originally performed using the detachable silicone balloon, endovascular arterial occlusion is currently achieved using coils, a process which can be limited by coil mass migration.
  
  
  METHODS
  We demonstrate the use of the Amplatzer vascular plug as a fixed anchor within the target parent vessel to facilitate coil-mediated occlusion, especially in vascular segments not encased by a bony canal. The technique was used successfully in two patients: a 90-year-old woman presenting with IIIrd and VIth cranial nerve palsy from a fusiform left cavernous internal carotid aneurysm and a 44-year-old man with distal thromboemboli from a fusiform dissecting-type right vertebral artery involving the origin of the posterior inferior cerebellar artery.
  
  
  RESULTS
  Both patients were treated successfully with proximal parent vessel occlusion using coils after deployment of an Amplatzer vascular plug proximal to the target lesion. With the Amplatzer device acting as a fixed anchor in the parent vessel, coils were deployed proximally in a compact configuration. After deployment of the vascular plugs and coils, hermetic occlusion of the parent vessel was documented angiographically.
  
  
  CONCLUSIONS
  The Amplatzer vascular plug can facilitate coil occlusion of large cervical vessels by acting as a focal coil and embolic material immobilizer, which can prevent coil mass migration and lead to improved packing density.
authors.affiliation: Department of Neurosurgery, Cerebrovascular and Endovascular Division, Tufts-New England Medical Center, Boston, Massachusetts 02111, USA.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Hoit
authors.forename: Clemens M
authors.initials: CM
authors.lastname: Schirmer
authors.forename: Adel M
authors.initials: AM
authors.lastname: Malek
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D020215:Carotid Artery, Internal, Dissection / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D002533:Cerebral Angiography; D003389:Cranial Nerve Diseases / Q000209:etiology / Q000503:physiopathology; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D007431:Intraoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D008297:Male; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D019736:Prostheses and Implants / Q000592:standards / Q000639:trends*; D016896:Treatment Outcome; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D020217:Vertebral Artery Dissection / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy
chemical_list: D000925:Anticoagulants