Basal or bolus dose, which is the key factor in CSII?
OBJECTIVE
To observe the value of HbA(1)c level evaluating the total daily basal insulin dose by continuous subcutaneous insulin infusion (CSII) in 268 patients with type 2 diabetes mellitus.


METHODS
5-point capillary blood glucose was monitored in pre- and post-CSII and the insulin dose which could stabilize blood glucose was defined as the total daily dose of insulin, including basal and bolus total dose. Correlation between HbA(1)c level and total daily dose of insulin in patients with type 2 diabetes mellitus was analyzed. Correlation between HbA(1)c level and 5-point capillary blood glucose was also analyzed.


RESULTS
Obvious correlation was observed between HbA(1)c level and the basal total daily dose of insulin if HbA(1)c was more than 9.3% (r=0.635, P<0.05). The average of 5-point capillary blood glucose was best correlated with HbA(1)c and fasting blood glucose next best.


CONCLUSIONS
HbA(1)c level can forecast basal total daily dose of insulin in CSII.
Yang
Nai-long
NL
Department of Endocrinology, Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China. nailongy@163.com
Xue
Bing
B
Lin
Peng
P
D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin