title: Preparation of aryl-alkylamines via electrophilic amination of functionalized arylazo tosylates with alkylzinc reagents.
abstract: [reaction: see text] A new electrophilic amination reaction of functionalized arylazo tosylates with alkylzinc halides or dialkylzinc reagents in THF leads to the corresponding hydrazines. A facile cleavage of the N-N bond is achieved using Raney nickel in refluxing ethanol, leading to substituted secondary aryl-alkylamines in 45-79% yield.
authors.affiliation: Department Chemie und Biochemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377 München, Germany.
authors.forename: Pradipta
authors.initials: P
authors.lastname: Sinha
authors.forename: Christiane C
authors.initials: CC
authors.lastname: Kofink
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel