title: Cognitive performance in Rett syndrome girls: a pilot study using eyetracking technology.
abstract: BACKGROUND
  Rett syndrome (RS) is a pervasive developmental disorder with cognitive and neuromotor impairments (including loss of handiness and loss of communicative skills).
  
  
  OBJECTIVE
  To verify whether girls with RS use their gaze intentionally, by observing their performance in three cognitive tasks: (1) verbal instruction condition (look at picture X), (2) recognition and matching of pictures (look at the one that is the same), and (3) categorization of pictures (look at the one that is similar).
  
  
  METHODS
  Seven girls diagnosed with RS according to DSM-IV criteria were studied. Eyegaze technology was used to record the girls' eye movements' responses to visual stimulation.
  
  
  RESULTS
  The comparison of fixation time on the alternatives revealed a higher percentage (62.4%) of correct alternatives (chi(2) = 76.31; P = 0.000). Of the seven children assessed, only one did not present predominance of fixations on the correct alternatives in any one of the tasks. One did well in all tasks. Six responded correctly to all verbal instructions.
  
  
  CONCLUSIONS
  The rate of correct answers suggests that there is measurable and intentional gaze in RS girls and it can be used as a path to explore their cognitive performance.
authors.affiliation: Development Disorders Program, Mackenzie Presbyterian University, São Paulo, Brazil. patriciamb@uol.com.br
authors.forename: P M
authors.initials: PM
authors.lastname: Baptista
authors.forename: M T
authors.initials: MT
authors.lastname: Mercadante
authors.forename: E C
authors.initials: EC
authors.lastname: Macedo
authors.forename: J S
authors.initials: JS
authors.lastname: Schwartzman
mesh_terms: D001938:Brazil; D002648:Child; D002675:Child, Preschool; D003071:Cognition; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D010775:Photic Stimulation / Q000379:methods; D010865:Pilot Projects; D021641:Recognition, Psychology / Q000502:physiology; D015518:Rett Syndrome / Q000523:psychology*; D013647:Task Performance and Analysis; D013997:Time Factors; D014706:Verbal Learning / Q000502:physiology