Use of genome browsers to locate your favorite genes.
The completion of whole-genome sequencing projects offers the opportunity of creating high-resolution maps of specific segments in a known genomic DNA sequence. For this purpose, several genome browsers have been created. They include the map-view (http://www.ncbi.nlm.nih.gov/mapview/), the Ensembl genome browser (http://www.ensembl.org/), and the genome browser at UCSC (http://genome.ucsc.edu/). For the beginners in the field, through a specific example, this chapter provides a step-by-step procedure for creating a map using the genome browser at UCSC. The example describes mapping, in the human genome, the promoter region of the NF-IL6 gene. The procedure is applicable to creating maps of the desired regions in genomes of other species available at the genome browser at UCSC.
Bina
Minou
M
Department of Chemistry, Purdue University, West Lafayette, IN, USA.
D002874:Chromosome Mapping / Q000379:methods*; D030541:Databases, Genetic; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D020407:Internet; D015141:Los Angeles; D012984:Software; D014495:Universities