title: Synthesis of imidazoles through the copper-catalyzed cross-cycloaddition between two different isocyanides.
abstract: The copper-catalyzed reaction between two different isocyanides produces the corresponding heteroaromatization products, imidazoles, in good yields. The reaction proceeds most probably through the activation of the sp3 C-H bond in the isocyanides by a copper catalyst, followed by a [3 + 2] cycloaddition between the cuprioisocyanide intermediates and arylisocyanides.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
authors.forename: Chikashi
authors.initials: C
authors.lastname: Kanazawa
authors.forename: Shin
authors.initials: S
authors.lastname: Kamijo
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D003486:Cyanides; D007093:Imidazoles; D003300:Copper