title: Mean-average wall shear stress measurements in the common carotid artery.
abstract: In this study we determined mean-average wall shear stress values in the common carotid artery and assessed if there is a difference in mean-average WSS between: 1) patients with bilateral carotid bifurcation disease and 2) similar-aged volunteers with no evidence of disease. Sixteen patients with bilateral disease of the carotid bifurcation, and 8 volunteers were included in the study. Magnetic resonance phase velocity mapping was used to determine velocity, flow, vessel cross-sectional dimensions, and mean-average WSS in the common carotid artery in both the patients and volunteers. Mean-average WSS in the common carotid artery was 7.5 +/- 2.5 dynes/cm2 in patients and 8.0 +/- 4.1 dynes/cm2 in volunteers. There was no significant difference in mean-average WSS, average velocity, peak velocity, flowrate, or vessel diameter in the common carotid artery between patients and volunteers.
authors.affiliation: Frederik Philips MR Research Center, Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322, USA. jnoshin@emory.edu
authors.forename: John N
authors.initials: JN
authors.lastname: Oshinski
authors.forename: Jay L
authors.initials: JL
authors.lastname: Curtin
authors.forename: Francis
authors.initials: F
authors.lastname: Loth
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D001809:Blood Viscosity; D017536:Carotid Artery, Common / Q000473:pathology / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D016022:Case-Control Studies; D003971:Diastole; D005260:Female; D006339:Heart Rate; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011673:Pulsatile Flow; D012189:Retrospective Studies; D033081:Shear Strength; D013314:Stress, Mechanical; D013599:Systole; D014655:Vascular Resistance