Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada.
The dysregulation of specific cellular functions in adipocytes, muscle cells, beta cells, and the liver leads to changes in systemic metabolic processes and ultimately to the pathophysiological manifestations that cause type 2 diabetes. The underlying cellular mechanisms are complex. The two meetings summarized here aimed to highlight the recent advances in our understanding of the molecular basis of feeding and nutrient storage and on the molecular consequences of obesity in terms of promoting risk for type 2 diabetes and cardiovascular disease.
Corvera
Silvia
S
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. silvia.corvera@umassmed.edu
Burkart
Alison
A
Kim
Ja-Young
JY
Christianson
Jennifer
J
Wang
Zhao
Z
Scherer
Philipp E
PE
D050156:Adipogenesis; D000818:Animals; D003920:Diabetes Mellitus / Q000503:physiopathology*; D004734:Energy Metabolism; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D009765:Obesity / Q000503:physiopathology*; D015398:Signal Transduction