title: Mechanically mediated electron transfer in model metallo-enzyme interfaces.
abstract: In this paper, we develop a physical analysis of charge transfer in the model 'metallo-enzyme' complex which consists of a synthetic redox-addressed assembly (a 'reaction center') hybridized with a quantum dot (a gold nanoparticle) and attached via molecular bridge (a spacer) to the electrode. This artificial system allows us to model electronic transduction in experimental redox ezyme-gold nanoparticle hybrid structure recently reported by Xiao et al. [Xiao, Y., Patolsky, F., Katz, E., Hainfeid, J.F., Willner, I., 2003. Science 299, 1877-1881]. We consider a photosensitive spacer that allows us to control the conductivity of the bridge by light. In this paper we will focus on a special type of nanoelectro-mechanical processes in this system and investigate single electronic effects in there.
authors.affiliation: Department of Applied Physics, Chalmers University of Technology, 412 96 Göteborg, Sweden.
authors.forename: L Yu
authors.initials: LY
authors.lastname: Gorelik
authors.forename: M V
authors.initials: MV
authors.lastname: Voinova
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D017076:Computer-Aided Design; D003460:Crystallization / Q000379:methods; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004579:Electron Transport; D004798:Enzymes / Q000737:chemistry*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006046:Gold / Q000737:chemistry*; D019563:Mechanics; D008839:Microelectrodes; D008956:Models, Chemical; D008958:Models, Molecular; D045663:Quantum Dots; D013314:Stress, Mechanical; D013499:Surface Properties
chemical_list: D004798:Enzymes; D006046:Gold