title: Stereoselective synthesis of highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans by tandem debenzylative cyclization of glycal derived 2,3-epoxy alcohols.
abstract: A new and highly efficient methodology for the construction of synthetically important highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans with three contiguous stereocenters is reported.
authors.affiliation: Division of Medicinal and Process Chemistry, Central Drug Research Institute (CDRI), Lucknow 226001, India.
authors.forename: L Vijaya Raghava
authors.initials: LV
authors.lastname: Reddy
authors.forename: Abhijeet Deb
authors.initials: AD
authors.lastname: Roy
authors.forename: Raja
authors.initials: R
authors.lastname: Roy
authors.forename: Arun K
authors.initials: AK
authors.lastname: Shaw
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D003500:Cyclization; D004852:Epoxy Compounds / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D004852:Epoxy Compounds; D005663:Furans