title: Radiation dose in abdominal computed tomography: the role of patient size and the selection of tube current.
abstract: OBJECTIVE
  To develop an algorithm for selecting tube current for computed tomography (CT), based on patient weight, that produces abdominal CT images of consistent image quality.
  
  
  METHODS
  We recorded body weight and radiation exposure parameters for 37 patients undergoing abdominal CT. Two radiologists blind to the CT technique independently graded 11 measures of image quality, using a 5-point (5 = excellent, 4 = good, 3 = acceptable, 2 = poor, and 1 = unacceptable) scale. These scores were averaged to generate an overall image quality score. Using linear regression, we found a target image noise level that corresponded to an overall image quality score of 4.5. We measured CT image noise in 9 uniformly attenuating regions of interest in the liver and abdominal aorta. We used linear regression to assess the relation between tube current and image noise. A prediction equation was developed to set the tube current in different-sized patients to produce images at the target noise level. Finally, we calculated the dose savings that would have resulted with this tube-current selection technique.
  
  
  RESULTS
  Image noise was correlated with patient weight (r2 = 0.81). At an overall image quality score of 4.5, the noise was 16 HU. Using this target noise value, we determined the required tube current for each patient weight and found that the use of this technique would have reduced radiation exposure for all patients weighing less than 70 kg. The dose reduction for the smallest patient (35.4 kg) was 72%.
  
  
  CONCLUSIONS
  To produce CT scans of similar quality, a simple prediction equation can be developed for any scanner to optimize radiation dose for patients of all body weights.
authors.affiliation: Department of Radiology, University of British Columbia, Vancouver General Hospital, Vancouver, BC. john.aldrich@vch.ca
authors.forename: John E
authors.initials: JE
authors.lastname: Aldrich
authors.forename: Silvia D
authors.initials: SD
authors.lastname: Chang
authors.forename: Ana-Marie
authors.initials: AM
authors.lastname: Bilawich
authors.forename: John R
authors.initials: JR
authors.lastname: Mayo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001835:Body Weight; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011860:Radiography, Abdominal / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*