title: [Sinonasal haemangiopericytoma of the nasal septum removed under endoscopic guidance].
abstract: Haemangiopericytomas originate in extravascular cells (pericytes). They are well-differentiated tumours with low potential for local recurrence or metastasis. The most common presenting symptoms are nasal obstruction and recurrent epistaxis. Differential diagnosis requires immunohistochemical staining. Treatment consists in wide surgical excision. Case report a 44-years old male turned up with symptoms of right-sided nasal obstruction and epistaxis. A reddish, tough tumour 10 mm in diameter was diagnosed, covered with unchanged mucous membrane with small ulceration 3 mm in diameter, growing in the nasal septum. The tumour was dissected from unchanged septal cartilage and removed under endoscopic guidance. Histopathological examination disclosed prolonged, multiangular cells, with no mitotic activity. Focal faint expression of actin was confirmed, while the tumour cells were negative for CD34, CD31, GFAP, EMA, CK and S-100. Endothelial cells were positive for CD31 and CD34. Epithelial cells were positive for EMA and CK. The results of differential diagnosis were consistent with the diagnosis of sinonasal haemongiopericytoma. The patient has been asymptomatic for 6 months. Conclusion. Transnasal endoscopic approach to the discussed sinonasal haemangiopericytoma located on the nasal septum allowed its optimal visualisation and removal with macroscopically sufficient margins.
authors.affiliation: Specjalistyczne Centrum Diagnostyczno-Zabiegowe Medicina, Kraków, Oddział Otolaryngologiczny. olafzag@poczta.onet.pl
authors.forename: Olaf
authors.initials: O
authors.lastname: Zagólski
authors.forename: Jan
authors.initials: J
authors.lastname: Kulisiewicz
authors.forename: Jerzy
authors.initials: J
authors.lastname: Kekuś
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Czajecki
mesh_terms: D000328:Adult; D004724:Endoscopy / Q000379:methods*; D006393:Hemangiopericytoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D009300:Nasal Septum / Q000601:surgery*; D009669:Nose Neoplasms / Q000473:pathology / Q000601:surgery*