Recent advances in capillary electrophoretic analysis of individual cells.
Because variability exists within populations of cells, single-cell analysis has become increasingly important for probing complex cellular environments. Capillary electrophoresis (CE) is an excellent technique for identifying and quantifying the contents of single cells owing to its small volume requirements and fast, efficient separations with highly sensitive detection. Recent progress in both whole-cell and subcellular sampling has allowed researchers to study cellular function in the areas of neuroscience, oncology, enzymology, immunology, and gene expression.
Arcibal
Imee G
IG
Department of Chemistry, Pennsylvania State University, University Park, PA, USA.
Santillo
Michael F
MF
Ewing
Andrew G
AG
D000818:Animals; D019075:Electrophoresis, Capillary / Q000379:methods* / Q000639:trends; D004798:Enzymes / Q000032:analysis / Q000378:metabolism; D005057:Eukaryotic Cells / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D007158:Immunologic Techniques; D008495:Medical Oncology / Q000379:methods; D009488:Neurosciences / Q000379:methods; D012333:RNA, Messenger / Q000032:analysis; D013347:Subcellular Fractions / Q000737:chemistry
D004798:Enzymes; D012333:RNA, Messenger