title: Right-sided cardiac involvement in osteogenesis imperfecta.
abstract: Skeletal manifestations are the hallmark of the osteogenesis imperfecta group of disorders. Extraskeletal involvement may, however, contribute significantly to morbidity. Structural cardiovascular anomalies reported in osteogenesis imperfecta include aortic root dilatation and aortic and mitral valve dysfunction. Herein is reported the first case of involvement of the right side of the heart in osteogenesis imperfecta.
authors.affiliation: Neonatal Service, University Hospitals of Leicester, UK. mineshkhashu@gmail.com
authors.forename: Minesh
authors.initials: M
authors.lastname: Khashu
authors.forename: Gustavo
authors.initials: G
authors.lastname: Pelligra
authors.forename: George G S
authors.initials: GG
authors.lastname: Sandor
authors.forename: Avash J
authors.initials: AJ
authors.lastname: Singh
mesh_terms: D045462:Endothelium-Dependent Relaxing Factors / Q000008:administration & dosage; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000503:physiopathology; D017380:Hypertrophy, Right Ventricular / Q000000981:diagnostic imaging / Q000473:pathology; D007231:Infant, Newborn; D007902:Length of Stay; D009569:Nitric Oxide / Q000008:administration & dosage; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000175:diagnosis; D010351:Patient Discharge; D010879:Piperazines / Q000008:administration & dosage; D011687:Purines; D013902:Radiography, Thoracic; D000068677:Sildenafil Citrate; D013450:Sulfones; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000002:abnormalities / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D045462:Endothelium-Dependent Relaxing Factors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D009569:Nitric Oxide; D000068677:Sildenafil Citrate