title: High levels of human anti-human antibodies to adalimumab in a patient not responding to adalimumab treatment.
authors.forename: G M
authors.initials: GM
authors.lastname: Bartelds
authors.forename: G J
authors.initials: GJ
authors.lastname: Wolbink
authors.forename: S
authors.initials: S
authors.lastname: Stapel
authors.forename: L
authors.initials: L
authors.lastname: Aarden
authors.forename: W F
authors.initials: WF
authors.lastname: Lems
authors.forename: B A C
authors.initials: BA
authors.lastname: Dijkmans
authors.forename: M T
authors.initials: MT
authors.lastname: Nurmohamed
mesh_terms: D000068879:Adalimumab; D000368:Aged; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000276:immunology*; D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab