title: Pulmonary lymphoma of mucosa-associated lymphoid tissue type followed as a long-standing indeterminate lesion in immunoglobulin M-type paraproteinemia.
abstract: An 82-year-old woman with monoclonal immunoglobulin (Ig) M-type paraproteinemia had a large opacity in the right lung field. The abnormal shadow on roentgenogram had persisted for more than 6 years since the initial diagnosis of paraproteinemia, which had been diagnosed as Waldenström's macroglobulinemia (WM). Computed tomography revealed the lesion as a pulmonary tumor which was finally diagnosed as a marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) after surgical removal. MALT lymphoma constitutes the majority of primary pulmonary lymphomas and is often associated with monoclonal IgM-type paraproteinemia as well as WM, a distinctive lymphoproliferative disorder. Pulmonary MALT lymphoma should frequently be suspected in case of an indeterminate pulmonary tumor with IgM-type paraproteinemia.
authors.affiliation: Department of General Thoracic Surgery, Rinku General Medical Center, Izumisano, Osaka, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sakamaki
authors.forename: Hyung-Eun
authors.initials: HE
authors.lastname: Yoon
authors.forename: Naofumi
authors.initials: N
authors.lastname: Oda
authors.forename: Hisao
authors.initials: H
authors.lastname: Uejima
authors.forename: Masami
authors.initials: M
authors.lastname: Imakita
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D020775:Thoracic Surgery, Video-Assisted; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D008258:Waldenstrom Macroglobulinemia / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery