Human exposure to polychlorinated naphthalenes through the consumption of edible marine species.
The concentrations of polychlorinated naphthalenes (PCNs) were determined in samples of 14 edible marine species (sardine, tuna, anchovy, mackerel, swordfish, salmon, hake, red mullet, sole, cuttlefish, squid, clam, mussel and shrimp), which are widely consumed by the population of Catalonia, Spain. The daily intake of PCNs associated with this consumption was also determined. A total of 42 composite samples were analyzed by HRGC/HRMS. The highest PCN levels (ng/kg of fresh weight) were found in salmon (227) followed by mackerel (95) and red mullet (68), while the lowest levels of total PCNs corresponded to shrimp (4.9) and cuttlefish (2.7). With the exception of cephalopods and shellfish species, in which tetra-CN was the predominant homologue, penta-CN (60%) was the predominant contributor to total PCNs. For a standard male adult, PCN intake through the consumption of edible marine species was 1.53 ng/day. The highest contributions to this intake (ng/day) corresponded to salmon (0.41), sole (0.28) and tuna (0.24). Concerning health risks, species-specific TEFs such as those reported by WHO and NATO for PCDD/Fs and dioxin-like PCBs are not currently available for PCN congeners. Although in general terms the results of the present study do not seem to suggest specific risks derived from exposure to PCNs through fish and seafood consumption, to establish the contribution of individual PCN congeners to total TEQ is clearly necessary for the assessment of human health risks.
Llobet
Juan M
JM
Toxicology Unit, School of Pharmacy, University of Barcelona, Avgda. Diagonal, 08028 Barcelona, Spain.
Falcó
Gemma
G
Bocio
Ana
A
Domingo
José L
JL
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004781:Environmental Exposure; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D008297:Male; D009281:Naphthalenes / Q000032:analysis*; D017747:Seafood / Q000032:analysis*
D006843:Hydrocarbons, Chlorinated; D009281:Naphthalenes