Klippel-Trenaunay syndrome: a multisystem disorder possibly resulting from a pathogenic gene for vascular and tissue overgrowth.
Klippel-Trenaunay syndrome is characterized by a triad of varicose veins, cutaneous capillary malformation, and hypertrophy of bone and soft tissue. Appropriate evaluation and treatment of children displaying features of the disease may minimize morbidity. The clinical appearance, etiology, genetics, diagnostics, and treatment of Klippel-Trenaunay syndrome are herein explored.
Kihiczak
George G
GG
Dermatology and Pediatrics, New Jersey Medical School, Newark, NJ 07103-2714, USA.
Meine
Jon G
JG
Schwartz
Robert A
RA
Janniger
Camila K
CK
D042501:Angiogenic Proteins / Q000235:genetics*; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics* / Q000628:therapy
C482200:AGGF1 protein, human; D042501:Angiogenic Proteins