title: Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjects.
abstract: The correlation between scores on the Barratt Impulsiveness Scale (BIS) and activation measured by functional magnetic resonance imaging in a dorsolateral prefrontal cortical (DLPFC) activating task was examined in 15 MDMA-using subjects and 19 controls. A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA. ivaldes@hal-pc.org
authors.forename: Ignacio H
authors.initials: IH
authors.lastname: Valdes
authors.forename: Joel L
authors.initials: JL
authors.lastname: Steinberg
authors.forename: Ponnada A
authors.initials: PA
authors.lastname: Narayana
authors.forename: Larry A
authors.initials: LA
authors.lastname: Kramer
authors.forename: Donald M
authors.initials: DM
authors.lastname: Dougherty
authors.forename: Alan C
authors.initials: AC
authors.lastname: Swann
authors.forename: Ernest S
authors.initials: ES
authors.lastname: Barratt
authors.forename: Frederick Gerard
authors.initials: FG
authors.lastname: Moeller
mesh_terms: D000328:Adult; D001921:Brain / Q000378:metabolism*; D006213:Hallucinogens; D006304:Health Status; D006801:Humans; D007175:Impulsive Behavior / Q000453:epidemiology* / Q000523:psychology*; D008279:Magnetic Resonance Imaging; D018817:N-Methyl-3,4-methylenedioxyamphetamine; D017397:Prefrontal Cortex / Q000378:metabolism; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000378:metabolism*
chemical_list: D006213:Hallucinogens; D018817:N-Methyl-3,4-methylenedioxyamphetamine