[Enteropathy-type T-cell lymphoma with CD8 and CD56 expression].
A 54-year-old male presented at a previous hospital with abdominal pain, where the patient was diagnosed as having abdominal and retroperitoneal lymphadenopathies by CT scan, then, he was referred to our hospital for further examination. Upper gastrointestinal endoscopy showed a tumor formation in the second portion of the duodenum, and there were medium sized atypical lymphocytes in biopsy specimens of the tumor. Since the atypical lymphocytes in the biopsy specimens were positive for CD3, CD8, CD56 and CD103 by immunostain, and had a rearrangement of the T-cell receptor 7-chain, the patient was diagnosed as having enteropathy-type T-cell lymphoma (ETL). Although ETL usually occurs as a complication of celiac disease, malabsorption and anti-gliadin antibodies, which are normally present in celiac disease, were not observed in this patient.
Sato
Tsutomu
T
Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine.
Matsunaga
Takuya
T
Iyama
Satoshi
S
Sakai
Toshiro
T
Murase
Kazuyuki
K
Sato
Yasushi
Y
Kobune
Masayoshi
M
Takimoto
Rishu
R
Kato
Junji
J
Niitsu
Yoshiro
Y
D017252:CD3 Complex / Q000096:biosynthesis; D019002:CD56 Antigen / Q000096:biosynthesis*; D016827:CD8 Antigens / Q000096:biosynthesis*; D004379:Duodenal Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D016099:Endoscopy, Gastrointestinal; D015334:Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; D006801:Humans; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000378:metabolism; D008297:Male; D008875:Middle Aged
D017252:CD3 Complex; D019002:CD56 Antigen; D016827:CD8 Antigens