title: Numerical simulations of phase contrast velocity mapping of complex flows in an anatomically realistic bypass graft geometry.
abstract: Combined in vitro experiments and numerical simulations were performed to study flow artifacts in phase contrast (PC) velocity mapping of steady flow through an anatomically realistic aortocoronary bypass graft model. The geometry was obtained through imaging and computational reconstruction of a left anterior descending (LAD) coronary artery of a porcine heart. Simulated images of through-plane velocity were obtained at selected slices of the geometry. These were then compared and contrasted with velocity images of corresponding sites that were obtained from in vitro experiments. The shift and distortion of the measured velocity profile was well predicted by the simulation, while trajectories obtained from particle tracking were shown to be useful in understanding the origins of the flow artifacts that were observed.
authors.affiliation: Department of Aeronautics, Imperial College London, South Kesington Campus, Prince Consort Road, London SW7 2BY United Kingdom. leek198@imperial.ac.uk
authors.forename: Kuan Loke
authors.initials: KL
authors.lastname: Lee
authors.forename: D J
authors.initials: DJ
authors.lastname: Doorly
authors.forename: D N
authors.initials: DN
authors.lastname: Firmin
mesh_terms: D000465:Algorithms; D000818:Animals; D001783:Blood Flow Velocity; D003198:Computer Simulation; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000473:pathology*; D006321:Heart / Q000000981:diagnostic imaging*; D007090:Image Interpretation, Computer-Assisted; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D011859:Radiography; D012984:Software; D013552:Swine