Cystic echinococcosis: progress and limits in epidemiology and immunodiagnosis.
This study discusses the epidemiology and immunodiagnosis of cystic echinococcosis (caused by Echinococcus granulosus). Despite the development of molecular methods to prepare antigens, nowadays there is no standard, highly sensitive, and specific test available for antibody detection in cystic echinococcosis. Furthermore, because serological tests can give only a limited support to clinical findings there is a clear need for new advances in immunodiagnosis of E. granulosus infection.
Siracusano
A
A
Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Roma, Italy.
Bruschi
F
F
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood* / Q000276:immunology; D000947:Antigens, Helminth / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000453:epidemiology; D004283:Dog Diseases / Q000175:diagnosis / Q000453:epidemiology; D004285:Dogs; D004443:Echinococcosis / Q000175:diagnosis / Q000453:epidemiology* / Q000662:veterinary; D048209:Echinococcus granulosus / Q000276:immunology* / Q000302:isolation & purification; D006023:Glycoproteins / Q000737:chemistry / Q000276:immunology; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D007558:Italy / Q000453:epidemiology; D007814:Larva; D008074:Lipoproteins / Q000737:chemistry / Q000276:immunology; D016036:Seroepidemiologic Studies; D012756:Sheep / Q000469:parasitology; D012757:Sheep Diseases / Q000175:diagnosis / Q000453:epidemiology; D015047:Zoonoses
D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D006023:Glycoproteins; D008074:Lipoproteins; C514021:antigen 5, Echinococcus granulosus; C514022:antigen B, Echinococcus granulosus