title: Modeling of interaction between therapeutic ultrasound propagation and cavitation bubbles.
abstract: In medical applications of high intense focused ultrasound the mechanism of interaction between ultrasound waves and cavitation bubbles is responsible for several therapeutic effects as well as for undesired side effects. Based on a two-phase continuum approach for bubbly liquids, in this paper a numerical model is presented to simulate these interactions. The numerical results demonstrate the influence of the cavitation bubble cloud on ultrasound propagation. In the case of a lithotripter pulse an increased bubble density leads to significant changes in the tensile part of the pressure waveform. The calculations are verified by measurements with a fiber optical hydrophone and by experimental results of the bubble cloud dynamics.
authors.affiliation: Institut für Höchstfrequenztechnik und Elektronik/Akustik, Universität Karlsruhe, Kaiserstrasse 12, D-76128 Karlsruhe, Germany. marko.liebler@ihe.uka.de <marko.liebler@ihe.uka.de>
authors.forename: Marko
authors.initials: M
authors.lastname: Liebler
authors.forename: Thomas
authors.initials: T
authors.lastname: Dreyer
authors.forename: Rainer E
authors.initials: RE
authors.lastname: Riedlinger
mesh_terms: D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D008096:Lithotripsy / Q000379:methods*; D045423:Microbubbles; D008954:Models, Biological; D008956:Models, Chemical; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012542:Scattering, Radiation; D012996:Solutions; D014464:Ultrasonic Therapy / Q000379:methods*
chemical_list: D012996:Solutions