Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.
Small-molecule hormones govern every aspect of the biology of plants. Many processes, such as growth, are regulated in similar ways by multiple hormones, and recent studies have revealed extensive crosstalk among different hormonal signaling pathways. These results have led to the proposal that a common set of signaling components may integrate inputs from multiple hormones to regulate growth. In this study, we tested this proposal by asking whether different hormones converge on a common set of transcriptional targets in Arabidopsis seedlings. Using publicly available microarray data, we analyzed the transcriptional effects of seven hormones, including abscisic acid, gibberellin, auxin, ethylene, cytokinin, brassinosteroid, and jasmonate. A high-sensitivity analysis revealed a surprisingly low number of common target genes. Instead, different hormones appear to regulate distinct members of protein families. We conclude that there is not a core transcriptional growth-regulatory module in young Arabidopsis seedlings.
Nemhauser
Jennifer L
JL
Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Hong
Fangxin
F
Chory
Joanne
J
D000040:Abscisic Acid / Q000378:metabolism; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D003517:Cyclopentanes / Q000378:metabolism; D003583:Cytokinins / Q000378:metabolism; D005030:Ethylenes / Q000378:metabolism; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D005875:Gibberellins / Q000378:metabolism; D006133:Growth Substances / Q000235:genetics / Q000378:metabolism; D007210:Indoleacetic Acids / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D054883:Oxylipins; D010937:Plant Growth Regulators / Q000096:biosynthesis / Q000235:genetics*; D050436:Regulatory Elements, Transcriptional / Q000235:genetics; D036226:Seedlings / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics*; D014158:Transcription, Genetic / Q000235:genetics*
D029681:Arabidopsis Proteins; D015415:Biomarkers; D003517:Cyclopentanes; D003583:Cytokinins; D005030:Ethylenes; D005875:Gibberellins; D006133:Growth Substances; D007210:Indoleacetic Acids; D054883:Oxylipins; D010937:Plant Growth Regulators; C011006:jasmonic acid; D000040:Abscisic Acid; C036216:ethylene; C007842:gibberellic acid