title: Assessment of hormonal and metabolic effects of dietary fiber in young Thai women.
abstract: OBJECTIVE
  To investigate whether daily dietary fiber intake at the reference level has any impact on studied hormones in a population of Thai women.
  
  
  METHODS
  Twenty-eight healthy Thai women (aged 18-20 years, BMI 18.5-25 kg/m2) with a history of regular menstrual cycles committed themselves to prepared food without changing the usual ratio of three major macronutrients. Dietary fiber from natural source at the amount of 8-10 g/day equal to their regular consumption was added to their daily diet for one menstrual cycle, then, increased to be 25-30 g/day for another 2 successive cycles. A single blood sample on midluteal day (day 18-23) was obtained in all three cycles. Plasma luteinizing hormone, follicle stimulating hormone, prolactin, estradiol, progesterone, cortisol, and insulin together with total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides were analyzed.
  
  
  RESULTS
  The measured hormones and lipids did not change significantly when compared between a control and two experimental cycles (p > 0.05).
  
  
  CONCLUSIONS
  Short-term consumption of 25-30 g/day fiber diet as recommended by the Reference Daily Intake (RDI) in a Thai population did not alter the studied hormones and lipids thus did not create any health problems.
authors.affiliation: Department of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. sisch@mahidol.ac.th
authors.forename: Supornpim
authors.initials: S
authors.lastname: Chearskul
authors.forename: Navaporn
authors.initials: N
authors.lastname: Supingklud
authors.forename: Anadi
authors.initials: A
authors.lastname: Nitithamyong
authors.forename: Prapaisri
authors.initials: P
authors.lastname: Sirichakwal
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D004043:Dietary Fiber / Q000008:administration & dosage*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008597:Menstrual Cycle / Q000502:physiology*; D011388:Prolactin; D018709:Statistics, Nonparametric; D013785:Thailand
chemical_list: D004043:Dietary Fiber; D006065:Gonadotropins, Pituitary; D007328:Insulin; D008055:Lipids; D011388:Prolactin; D006854:Hydrocortisone