The MM2-cortical form of sporadic Creutzfeldt-Jakob disease presenting with visual disturbance.
A subclass of sporadic Creutzfeldt-Jakob disease (sCJD) characterized by onset with visual symptoms (Heidenhain variant) has been reported to belong to the MM1 or MV1 type according to Parchi's classification. The authors report a 65-year-old woman with MM2-cortical sCJD with slowly progressive visual disturbance as the initial symptom. Diffusion-weighted MRIs revealed hyperintensity in both occipital cortices at an early stage.
Nozaki
I
I
Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan. ichi51@med.kanazawa-u.ac.jp
Hamaguchi
T
T
Noguchi-Shinohara
M
M
Ono
K
K
Shirasaki
H
H
Komai
K
K
Kitamoto
T
T
Yamada
M
M
D000368:Aged; D007562:Creutzfeldt-Jakob Syndrome / Q000145:classification / Q000150:complications* / Q000235:genetics; D004252:DNA Mutational Analysis; D005260:Female; D006801:Humans; D014786:Vision Disorders / Q000209:etiology*