title: [Related factors and prognosis of hepatic metastasis and peritoneal dissemination in gastric cancer].
abstract: OBJECTIVE
  To investigate the related factors and prognosis of peritoneal dissemination and hepatic metastasis in gastric cancer, and the impact of palliative surgery on the prognosis.
  
  
  METHODS
  The clinicopathologic and follow-up data of the patients with gastric carcinoma treated in our hospital from Aug. 1994 to Jul. 2005 were analyzed retrospectively.
  
  
  RESULTS
  The clinicopathologic factors correlated with peritoneal dissemination included serosal penetration, whole stomach cancer, undifferentiated type, female and hepatic metastasis, while those correlated with hepatic metastasis included Borrmann IV, lymph node metastasis and peritoneal dissemination (P< 0.05). The postoperative one-year survival rate of the patients with hepatic metastasis (H group) were lower than that of the patients with peritoneal dissemination (P group)(P< 0.05). The one- year survival rate of the patients with peritoneal dissemination undergoing palliative resection was significantly higher than that of the patients undergoing by-pass operation or feeding neostomy, and exploratory laparotomy (P< 0.05), while there was no significant difference among the three groups of the patients with hepatic metastasis.
  
  
  CONCLUSIONS
  The short-term prognosis of the patients with hepatic metastasis is poorer than that of the patients with peritoneal dissemination. Palliative resection could improve the short-term survival rate of the patients with peritoneal dissemination, while it had no significant impact on the survival rate of the patients with hepatic metastasis.
authors.affiliation: Department of Gastrointes tinopancreatic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Wang
authors.forename: Wen-hua
authors.initials: WH
authors.lastname: Zhan
authors.forename: Yu-long
authors.initials: YL
authors.lastname: He
authors.forename: Shi-rong
authors.initials: SR
authors.lastname: Cai
authors.forename: Jun-sheng
authors.initials: JS
authors.lastname: Peng
authors.forename: Chuang-qi
authors.initials: CQ
authors.lastname: Chen
authors.forename: Jin-ping
authors.initials: JP
authors.lastname: Ma
authors.forename: Zhang-qing
authors.initials: ZQ
authors.lastname: Zheng
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010534:Peritoneal Neoplasms / Q000401:mortality / Q000556:secondary*; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology*; D015996:Survival Rate