[Estimation of effectiveness of the prevention of sudden cardiac death in patients with myocardial infarction].
On the basis of open, randomized, inspected trial during 1 year period, the effectiveness of inclusion in the standard treatment of beta blockers, metoprolol and Carvedilol for prophylaxis of sudden cardiac death has been investigated. 112 patients with a myocardial infarction in the age of from 45 till 70 years from the contingent of the IV hospital of Tbilisi were included in the trial. Absolute and relative risk reductions were defined. Statistical analysis was performed by chi2 (Pearson) criterion using SPSS 11.5. The relative risk of SCM in the group of patients who got the treatment by Carvedilol was 0,28 (95% CI: 0,12-0,62), relative risk reduction of SCM was 0,97 (95%CI: 0,59-0,99), absolute risk reduction - 0,30 (95%CI: 0,15-0,45).
Nakashidze
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NM
Machavariani
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PT
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D000077261:Carvedilol; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality*; D011412:Propanolamines / Q000627:therapeutic use*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol; D008790:Metoprolol