title: [New study evaluating online haemodiafiltration for the reduction of cardiovascular morbidity and mortality in patients undergoing chronic haemodialysis].
abstract: Removal of uraemic toxins can be increased by online haemodiafiltration. At present, it is unclear whether online haemodia-filtration ultimately improves clinical outcomes in chronic haemodialysis patients. The Dutch 'Convective transport study' (CONTRAST) is an ongoing trial comparing standard haemodialysis with online haemodiafiltration. This randomised controlled trial will provide substantial clinical evidence on the effects of haemodiafiltration on fatal and non-fatal cardiovascular events and all-cause mortality, compared with standard haemodialysis.
authors.affiliation: Universitair Medisch Centrum Utrecht, Postbus 85.500, 3508 GA Utrecht.
authors.forename: E L
authors.initials: EL
authors.lastname: Penne
authors.forename: P J
authors.initials: PJ
authors.lastname: Blankestijn
authors.forename: M L
authors.initials: ML
authors.lastname: Bots
authors.forename: M A
authors.initials: MA
authors.lastname: van den Dorpel
authors.forename: M P C
authors.initials: MP
authors.lastname: Grooteman
authors.forename: M J
authors.initials: MJ
authors.lastname: Nubé
authors.forename: P M
authors.initials: PM
authors.lastname: ter Wee
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality* / Q000517:prevention & control; D002986:Clinical Trials as Topic; D017583:Hemodiafiltration / Q000379:methods*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D009862:Online Systems; D016896:Treatment Outcome