title: [The influence of psychosocial factors in developments of ischemic heart disease and arterial hypertension in persons with genetic predisposition].
abstract: The purpose of the work was to investigate the influence of psychosocial factors on the development of ischemic heart disease and arterial hypertension in persons with genetic predisposition to cardiovascular disease. Three groups of patients were investigated: 72 patients with AH, 175 patients with IHD (74 with angina pectoris and 101 with angina pectoris and myocardial infarction) and 164 patients with IHD and AH. In nearest relation of 283 (69/03%) patients from 410 were found the presence of high arterial hypertension, myocardial infarction, diabetes and obesity. In this persons reliable relationship were found between psychosocial and genetic factors (in persons with genetic predisposition to cardiovascular disease were found high rate of anxiety, frequent stressful situations at work and in family, psychoemotional overloads). On the basis of our investigations it may be concluded that the genetic and psychosocial factors together play important role in the development of IHD and AH, that perhaps caused from influence of genetic factors on capable of to overcome the stress.
authors.forename: N T
authors.initials: NT
authors.lastname: Kiknadze
authors.forename: G V
authors.initials: GV
authors.lastname: Kavtaradze
mesh_terms: D000328:Adult; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000235:genetics / Q000523:psychology*; D011379:Prognosis; D012307:Risk Factors; D013315:Stress, Psychological; D011795:Surveys and Questionnaires