title: Determinants of early outcome in spontaneous lobar cerebral hemorrhage.
abstract: OBJECTIVE
  To identify determinants of early outcome in spontaneous lobar hemorrhage.
  
  
  METHODS
  From 2500 acute stroke patients included in a prospective hospital-based stroke registry over a 12-year period, 97 cases of lobar hematoma were selected. Determinants of in-hospital mortality were studied in multiple regression models.
  
  
  RESULTS
  Lobar hematomas accounted for 3.9% of all acute stroke patients and 35.9% of intracerebral hemorrhages. The presence of chronic obstructive pulmonary disease (COPD) was a significant predictive variable in the model based on demographic variables and vascular risk factors [odds ratio (OR): 17.18; 95% CI: 1.77-166.22] and in the model based on these variables plus clinical data (OR: 15.12; 95% CI: 1.27-179.59). Other predictive variables included altered consciousness, previous cerebral infarct and chronic liver disease.
  
  
  CONCLUSIONS
  COPD appeared as the most important predictor of death during hospitalization after lobar cerebral hemorrhage, a finding not generally acknowledged earlier.
authors.affiliation: Cerebrovascular Division, Department of Neurology, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain. aarboix@hscor.com
authors.forename: A
authors.initials: A
authors.lastname: Arboix
authors.forename: C
authors.initials: C
authors.lastname: Manzano
authors.forename: L
authors.initials: L
authors.lastname: García-Eroles
authors.forename: J
authors.initials: J
authors.lastname: Massons
authors.forename: M
authors.initials: M
authors.lastname: Oliveres
authors.forename: O
authors.initials: O
authors.lastname: Parra
authors.forename: C
authors.initials: C
authors.lastname: Targa
mesh_terms: D000368:Aged; D002543:Cerebral Hemorrhage / Q000150:complications / Q000175:diagnosis / Q000401:mortality*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D012042:Registries; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000175:diagnosis / Q000209:etiology / Q000401:mortality*; D015996:Survival Rate