title: Acute limb ischemia due to ergotism.
abstract: Acute ischemia of an extremity potentially threatens limb loss and occasionally the life of the patient. We are reporting two cases of extremity ischemia secondary to ergot poisoning. The first patient was a 60 years old woman, who presented with a 15 days history of ischemia of the left arm with gangrene of the fingers and pain in the resting right hand for one day. Right brachial artery catheterization showed severe spasm of the artery which was resolved by passage of the inflated balloon catheter. She underwent amputation for gangrene of the left hand. The second patient presented with bilateral symmetrical ischemia of the lower extremities which improved upon withdrawal of the ergot containing medicine. She responded to nifedipine.
authors.affiliation: Department of Surgery, Section of Vascular Surgery, Aga Khan University, Karachi, Pakistan.
authors.forename: Iram
authors.initials: I
authors.lastname: Naz
authors.forename: Ziad
authors.initials: Z
authors.lastname: Sophie
mesh_terms: D000208:Acute Disease; D000328:Adult; D000671:Amputation, Surgical; D004881:Ergotism / Q000150:complications* / Q000628:therapy; D005260:Female; D005734:Gangrene / Q000209:etiology / Q000628:therapy; D006225:Hand / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007511:Ischemia / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents; D009543:Nifedipine