title: [Evaluation of functional state of blood platelets in patients infected with Echinococcus granulosus].
abstract: Blood platelets actively participate in defense mechanisms of the organism. eg. in antiparasitic immunology. The study involved 17 patients infected with Echinococcus granulosus. Blood for analysis was collected twice, before treatment (E1) and after it (E2). Control group consisted of 30 healthy people. The concentrations of beta-thromboglobulin and platelet factor 4 were assayed using a set of ASSERACHROM (Boehringer Mannheim) according to the immunoenzymatic method with labelled antibodies. The level of platelet factor 4 (before and after the antiparasitic treatment) indicates platelet activation by parasite.
authors.affiliation: Zakład Laboratoryjnej Diagnostyki Klinicznej, Akademia Medyczna, 15-274 Bialystok, J. Waszyngtona 15A.
authors.forename: J
authors.initials: J
authors.lastname: Matowicka-Karna
authors.forename: H
authors.initials: H
authors.lastname: Kemona
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use; D001792:Blood Platelets / Q000276:immunology*; D004443:Echinococcosis / Q000097:blood* / Q000188:drug therapy / Q000276:immunology*; D048209:Echinococcus granulosus; D006801:Humans; D008875:Middle Aged; D015539:Platelet Activation / Q000276:immunology; D010976:Platelet Count; D010978:Platelet Factor 4 / Q000378:metabolism; D001620:beta-Thromboglobulin / Q000378:metabolism
chemical_list: D000977:Antiparasitic Agents; D001620:beta-Thromboglobulin; D010978:Platelet Factor 4