Renal medullary carcinoma. Case report and review of the literature.
Young patients with sickle cell trait or disease present a higher risk for renal medullary carcinoma, an aggressive renal tumor, with dismal prognosis, with a median survival of 4 months from the time of diagnosis. We report a 26-year-old patient with a 2-month history of bone pain at the right iliac crest, loss of weight, recurrent macroscopic hematuria and abdominal mass. Imaging studies demonstrated a 10-cm mass in the right kidney. Pathological evaluation revealed a medullary carcinoma and the patient died after 4 months, despite adjuvant treatment. Whenever a patient with sickle cell trait or disease presents with hematuria and/or flank pain, the possibility of a renal medullary carcinoma should always be kept in mind, with thorough investigation and expeditious treatment.
Leitão
Victor Augusto
VA
Division of Urology, Universidade Estadual de Campinas, Campinas, Brazil. victorleitao@uol.com.br
da Silva
Walter
W
Ferreira
Ubirajara
U
Denardi
Fernandes
F
Billis
Athanase
A
Rodrigues Netto
Nelson
N
D000328:Adult; D018276:Carcinoma, Medullary / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery; D008297:Male