title: Multiple reversible MR signal changes caused by Epstein-Barr virus encephalitis.
abstract: This report presents the imaging findings of an unusual case of Epstein-Barr virus (EBV) encephalitis. A young man presented with a short-lasting history of febrile infection, neuropsychologic deficits, ataxia, and seizures. MR imaging revealed fully reversible signal intensities (T2, diffusion-weighted imaging with a decreased apparent diffusion coefficient) in the splenium of the corpus callosum and both posterior hemispheres. EBV infection must be added to the list of differential diagnoses of (reversible) splenial lesions.
authors.affiliation: Department of Neurology, Friedrich-Schiller-University, Erlanger Allee 101, 07740 Jena, Germany. hagemann@med.uni-jena.de
authors.forename: G
authors.initials: G
authors.lastname: Hagemann
authors.forename: H-J
authors.initials: HJ
authors.lastname: Mentzel
authors.forename: H
authors.initials: H
authors.lastname: Weisser
authors.forename: A
authors.initials: A
authors.lastname: Kunze
authors.forename: C
authors.initials: C
authors.lastname: Terborg
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001259:Ataxia / Q000821:virology; D003337:Corpus Callosum / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis; D038524:Diffusion Magnetic Resonance Imaging; D018792:Encephalitis, Viral / Q000175:diagnosis*; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D005500:Follow-Up Studies; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral