An intradural extramedullary tuberculoma of the spinal cord in a non-HIV-infected patient: case report and review of the literature.
Spinal tuberculomas are extrapulmonary manifestations of tuberculosis involving the central nervous system. They are characterized as extradural, intradural extramedullary, or intradural, according to their location. Intradural extramedullary tuberculomas are extremely rare. There have been only 24 case reports found in English language literature. Our case is the only documented intradural extramedullary tuberculoma in a non-HIV-infected patient in North America. A literature review using a Medline search from 1966 to the present is performed to characterize the clinical spectrum of the three types of tuberculomas and review the diagnosis and management of this potentially curable disease. An analysis of the cases of intradural extramedullary tuberculomas published since 1984 is performed to highlight the unique characteristics of this rare disease.
Luo
Lan
L
Department of Internal Medicine, Coastal AHEC, University of North Carolina School of Medicine, 2131 South 17th Street, Wilmington, NC 28409, USA. lan.luo@coastalahec.org
Pino
Joseph
J
D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D013904:Thoracic Vertebrae; D014375:Tuberculoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D020306:Tuberculosis, Central Nervous System / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery
D000995:Antitubercular Agents