title: [Image registration for radiation therapy: Practical aspects and quality control].
abstract: The development of conformal radiotherapy techniques (CRT) and intensity modulated CRT requires an accurate delineation of target structures and organs at risk. Thus, additional information provided by anatomical and/or functional imaging modalities can be used for volume of interest determination combined with traditionally used Computed Tomography imaging (CT): for instance, functional or morphological Magnetic Resonance Imaging (f MRI or m MRI) or Positron Emission Tomography (PET). A prerequisite to the simultaneous use of this information is image registration. Due to the differences between the images and the information they provide, a quality control of image registration process for radiotherapy is mandatory. The purpose of this article is to present the difficulties in implementing such controls and to show the necessity for a clinical validation on patient's images. The last part of this work presents the possible interest in using f MRI to help radio-oncologists in the treatment planning for gliomas associated to image coregistration and quality control considerations.
authors.affiliation: Service de physique médicale, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif, France. bonniaud@igr.fr
authors.forename: G
authors.initials: G
authors.lastname: Bonniaud
authors.forename: A
authors.initials: A
authors.lastname: Isambert
authors.forename: F
authors.initials: F
authors.lastname: Dhermain
authors.forename: A
authors.initials: A
authors.lastname: Beaudré
authors.forename: I
authors.initials: I
authors.lastname: Ferreira
authors.forename: M
authors.initials: M
authors.lastname: Ricard
authors.forename: D
authors.initials: D
authors.lastname: Lefkopoulos
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy; D003952:Diagnostic Imaging / Q000379:methods* / Q000592:standards; D005910:Glioma / Q000532:radiotherapy; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods* / Q000592:standards; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D011786:Quality Control; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods / Q000592:standards; D011881:Radiotherapy, Computer-Assisted / Q000379:methods / Q000592:standards; D020266:Radiotherapy, Conformal; D050397:Radiotherapy, Intensity-Modulated; D014057:Tomography, X-Ray Computed