title: [Advances in the studies of Kallmann syndrome].
abstract: Kallmann syndrome (KS) is a rare hereditary disease. It is characterized by hypogonadotrophic hypogonadism in association with anosmia or hyposmia. At present, three modes of inheritance and genes related to KS have been identified. This review focuses on the clinical diagnosis and advances in the studies of the pathogenesis gene for Kallmann syndrome.
authors.affiliation: Laboratory of Reproduction and Genetics, Nanjing General Hospital, Nanjing command, PLA, Nanjing, Jiangsu 210002, China.
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Hao
authors.forename: Ying-xia
authors.initials: YX
authors.lastname: Cui
mesh_terms: D003937:Diagnosis, Differential; D016326:Extracellular Matrix Proteins / Q000235:genetics; D006801:Humans; D017436:Kallmann Syndrome / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D008297:Male; D009419:Nerve Tissue Proteins / Q000235:genetics; D035583:Rare Diseases; D051496:Receptor, Fibroblast Growth Factor, Type 1 / Q000235:genetics
chemical_list: C076266:ANOS1 protein, human; D016326:Extracellular Matrix Proteins; D009419:Nerve Tissue Proteins; D051496:Receptor, Fibroblast Growth Factor, Type 1