Cobalt-catalyzed aziridination with diphenylphosphoryl azide (DPPA): direct synthesis of N-phosphorus-substituted aziridines from alkenes.
A new catalytic aziridination system that consists of cobalt(II) tetraphenylporphyrin [Co(TPP)] as the catalyst and diphenylphosphoryl azide (DPPA) as the nitrene source has been developed. The cobalt-based catalytic system allows direct synthesis of N-phosphorus-substituted aziridines from alkenes with dinitrogen as the byproduct. Cobalt ion seems essential to the catalytic aziridination with DPPA as no or only trace amounts of the desired products were observed with other metal complexes of tetraphenylporphyrin.
Gao
Guang-Yao
GY
Department of Chemistry, University of Tennessee, Knoxville, Tennessee 37996-1600, USA.
Jones
Jess E
JE
Vyas
Renu
R
Harden
Jeremiah D
JD
Zhang
X Peter
XP