Consideration of future requirements for Raman microbiology as an examplar for the ab initio development of informatics frameworks for emergent OMICS technologies.
Raman spectroscopy of single bacteria provides an OMIC-like view of the chemical status of individual cells, reporting on metabolism, cell stress and growth, and is likely to become a significant tool in environmental and medical microbiology. We advocate the early development of integrated data models and informatics frameworks, in parallel with the development of Raman hardware and experimental protocols, in order to maximize the benefits of this emerging OMIC technology to the research community.
Huang
Wei E
WE
Molecular Microbiology Ecology and Environmental Biotechnology Sections, Oxford, United Kingdom.
Spiers
Andrew J
AJ
D019295:Computational Biology / Q000379:methods / Q000592:standards*; D008828:Microbiological Techniques / Q000592:standards; D008829:Microbiology / Q000592:standards*; D013059:Spectrum Analysis, Raman / Q000592:standards*