Neuroimaging of pain perception in Dutch veterans with and without posttraumatic stress disorder: preliminary results.
This article presents initial data on the application of a pain protocol in posttraumatic stress disorder (PTSD) to assess the neural circuitry that is involved in the disorder, with a special interest in the role of the anterior cingulate cortex (ACC). Preliminary analysis demonstrated a specific and differentiated role for the ACC. Fixed affects analysis demonstrated that stimuli subjectively perceived as more painful resulted in increased activation of the caudal ACC, whereas less painful stimuli resulted in increased activation of the rostral ACC in both groups.
Geuze
Elbert
E
Department of Military Psychiatry, Central Military Hospital, Heidelberglaan, 100 3584, CX, Utrecht, The Netherlands.
Vermetten
Eric
E
Jochims
Anja
A
Bohus
Martin
M
Schmahl
Christian
C
Westenberg
Herman
H
D000328:Adult; D002540:Cerebral Cortex / Q000473:pathology; D006225:Hand; D006358:Hot Temperature; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D009426:Netherlands; D010146:Pain / Q000473:pathology* / Q000523:psychology*; D010147:Pain Measurement; D011569:Psychiatric Status Rating Scales; D013313:Stress Disorders, Post-Traumatic / Q000473:pathology* / Q000523:psychology*; D014728:Veterans / Q000523:psychology*