Eu(III) dithiocarbamate complex and N-p-tolylsulfonylphenylalanine as a novel chiral catalyst for the asymmetric synthesis of cyanohydrins.
The use of a new chiral lanthanide complex derived from a europium dithiocarbamate complex and a N-tosylated amino acid for the asymmetric synthesis of cyanohydrins is described. In some cases, high enantioselectivities were observed.
Vale
Juliana A
JA
Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50740-540 Recife/PE, Brazil. julianadqf@yahoo.com.br
Faustino
Wagner M
WM
Menezes
Paulo H
PH
de Sá
Gilberto F
GF
D002384:Catalysis; D005063:Europium; D009570:Nitriles / Q000138:chemical synthesis*; D010649:Phenylalanine / Q000737:chemistry; D013237:Stereoisomerism; D013859:Thiocarbamates / Q000737:chemistry
D009570:Nitriles; D013859:Thiocarbamates; C430593:cyanohydrin; D005063:Europium; D010649:Phenylalanine