Ochratoxin a in maternal and foetal blood and in maternal milk.
Ochratoxin A (OA) levels were measured in blood serum of mothers foetuses and in mothers' milk. The mean concentration of OA in maternal serum was 1.14 ng/ml and in umbilical cord blood serum it was 1.96 ng/ml. The mean ratio of OA concentrations in maternal and foetal blood serum was 1.96. In maternal milk OA was found in 5 out of 13 studied samples. The mean intake of OA with mother's milk was not exceeding the tolerable daily intake for adults, nevertheless it was near 60% of TDI. The OA concentration ratio in maternal blood serum versus that in milk was 0.0058 on average. These results confirm the correlation between OA concentration maternal and foetal blood serum, and between OA concentration in maternal serum and milk.
Postupolski
Jacek
J
National Institute of Hygiene, Department of Food and Consumer Articles Research, Warsaw, Poland. jpostupolski@pzh.gov.pl
Karłowski
Kazimierz
K
Kubik
Paweł
P
D000328:Adult; D002273:Carcinogens / Q000032:analysis*; D002853:Chromatography, Liquid / Q000379:methods; D004784:Environmental Monitoring; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods; D006801:Humans; D008431:Maternal-Fetal Exchange; D008895:Milk, Human / Q000737:chemistry*; D009793:Ochratoxins / Q000032:analysis*; D011247:Pregnancy / Q000097:blood; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D002273:Carcinogens; D009793:Ochratoxins; C025589:ochratoxin A