title: Clinical characteristics of patients with segmental renal infarction.
abstract: BACKGROUND
  Renal infarction is usually an underestimated disease due to its rare and non-specific presentations; the renal survival of these patients is not well studied. The aim of the present analysis is to study the clinical features and outcome in patients who had documented renal infarction.
  
  
  METHODS
  Twenty-two patients (12 men and 10 women, mean age of 57.7 +/- 3.44 years (28.4-83.3 years)) with image-confirmed segmental renal infarction in the past 15 years were enrolled. All patients were followed up at outpatient department with a median of 4 years (1-14 years). Initial and follow-up clinical characteristics and laboratory results were recorded.
  
  
  RESULTS
  The most common underlying disease was cardiovascular disease. Renal infarction often presented with non-specific symptoms, including flank pain (55%), vague abdominal pain (50%), nausea/vomiting (46%) and fever (27%). The levels of leucocytes, lactate dehydrogenase, blood urea nitrogen and serum creatinine were all elevated at admission. The early diagnosis group (12/22) had more obvious flank pain, nausea/vomiting (P < 0.001) and higher alanine transaminase (P = 0.02). It also predisposed to undergo antiplatelet or anticoagulant therapy (all P < 0.04). During follow up, there was no recurrence in the whole study group, and a trend of better recovery of renal function was noted in the early diagnosis group.
  
  
  CONCLUSIONS
  The serum creatinine level correlates with longer hospitalization length (P < 0.05). As regards long-term prognosis, no definite factor or treatment was found to have significant effect in segmental renal infarction patients. However, early diagnosis and early initiation of treatment seems to have a positive effect on future renal outcome.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan.
authors.forename: Pei-Lun
authors.initials: PL
authors.lastname: Chu
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Wei
authors.forename: Jenq-Wen
authors.initials: JW
authors.lastname: Huang
authors.forename: Shih-I
authors.initials: SI
authors.lastname: Chen
authors.forename: Tzong-Shinn
authors.initials: TS
authors.lastname: Chu
authors.forename: Kwan-Dun
authors.initials: KD
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007238:Infarction / Q000150:complications / Q000175:diagnosis*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies