AngioJet experience from the multi-center STENT Registry.
OBJECTIVE
To explore the utilization and clinical outcomes of AngioJet Rheolytic thrombectomy from the Strategic Transcatheter Evaluation of New Therapies (STENT) multi-center prospective registry from May 2003 through December 2005.


METHODS
Prospective consent was sought for all consecutive percutaneous coronary intervention (PCI) patients at all institutions and achieved in 84% of all patients. Of these, clinical follow-up at 9 months was achieved in 94% of eligible patients at all institutions.


RESULTS
Of a total of 9,707 patients, AngioJet was utilized in 3-4% of all procedures, including 12-14% of all procedures with thrombolysis in myocardial infarction (TIMI) grade 3 thrombus or greater and 10-12% of acute evolving MI patients. Nine-month clinical outcomes showed similar mortality rates for patients treated with AngioJet (5.0%) versus those with no thrombectomy (6.5%) for patients with thrombus grade 3 or greater, despite the higher clinical risk profile of the AngioJet patient population due to a higher percentage of cardiogenic shock and larger thrombus.


CONCLUSIONS
The results of this larger, multi-center registry indicate that AngioJet thrombectomy, when selected in general clinical practice for high risk patients with thrombus, results in non-significant numerically lower rate of mortality with no indication of safety issues.
Simonton
Charles A
CA
Sanger Clinic, Carolinas Heart Institute, Charlotte, North Carolina 28203, USA. pcichuck@att.net
Brodie
Bruce R
BR
Wilson
Hadley
H
Haber
Robert
R
Kowalchuk
Glen
G
Rinaldi
Michael
M
Cedarholm
John
J
Humphrey
Angela
A
Laurent
Sherry
S
D000368:Aged; D006328:Cardiac Catheterization / Q000592:standards / Q000706:statistics & numerical data*; D003328:Coronary Thrombosis / Q000150:complications / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D012042:Registries; D012307:Risk Factors; D012770:Shock, Cardiogenic / Q000150:complications; D017131:Thrombectomy / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data*; D016896:Treatment Outcome