On-bead screening of a library to detect host-guest complexation by an aniline reporter.
We developed a new labeling reagent and a color assay system in water to detect binding between target molecules and library members on beads, which is free of label-induced artifacts that can cause misleading results.
Kubo
Miwa
M
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Nishimoto
Ryosuke
R
Doi
Masanori
M
Kodama
Mitsuaki
M
Hioki
Hideaki
H
D000814:Aniline Compounds / Q000737:chemistry*; D004396:Coloring Agents / Q000737:chemistry; D008863:Microspheres; D015394:Molecular Structure; D010316:Particle Size; D019151:Peptide Library; D010455:Peptides / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism; D013997:Time Factors
D000814:Aniline Compounds; D004396:Coloring Agents; D019151:Peptide Library; D010455:Peptides; C023650:aniline