Short-term fasting differentially alters PACAP and VIP levels in the brains of rat and chicken.
The present article investigated the levels of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) in the brains of rats and chickens 12, 36, and 84 h after starvation. PACAP levels increased in both species, 12 h after food deprivation in rats, and with a 24-h delay in chickens. VIP levels showed a more complex pattern: a gradual increase in the hypothalamus and telencephalon, and a significant decrease in the brain stem of rats. In chickens, a decrease was observed in every brain area after 36 h of starvation. These data show that PACAP and VIP are differentially regulated and are involved in the regulatory processes under a food-restricted regimen, and are differentially altered in nocturnal and diurnal species.
Jozsa
Rita
R
Department of Anatomy, Neurohumoral Regulations Research Group of the Hungarian Academy of Sciences, University of Pécs, 7624 Pécs, Szigeti u 12. Hungary.
Nemeth
Jozsef
J
Tamas
Andrea
A
Hollosy
Tibor
T
Lubics
Andrea
A
Jakab
Balazs
B
Olah
Andras
A
Lengvari
Istvan
I
Arimura
Akira
A
Reglödi
Dora
D
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002645:Chickens; D005215:Fasting; D008297:Male; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
D051219:Pituitary Adenylate Cyclase-Activating Polypeptide; D014660:Vasoactive Intestinal Peptide