title: [Neurogliaform cells: neurochemistry, spatial arrangement, and their role in the neocortical inhibitory system].
abstract: The neurogliaform cells (NGFC) localized in area 4 of the human motor cortex were found to express choline acetyl transferase (ChAT), GABA, and calbindin. ChAT-positive neurons were located in cortical layer II. Their dendrites lay in a close proximity to those of pyramid cells, neighbouring neurogliaform cells, and bodies and dendrites of other cortical neurons. The NGFCs revealed by Golgi staining fell into two groups. Cells of the first group had locally (within cortical layer II) spreading axons, while those of the second group had axons extending into the adjacent layers. Neurochemical heterogeneity of NGFCs is discussed in the context of information processing in cortical modules and interaction of excitatory and inhibitory interneurons.
authors.forename: S G
authors.initials: SG
authors.lastname: Kalinichenko
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Dudina
authors.forename: P A
authors.initials: PA
authors.lastname: Motavkin
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D064026:Calbindins; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D006801:Humans; D019579:Neocortex / Q000166:cytology* / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009433:Neural Inhibition; D009448:Neurochemistry; D009457:Neuroglia / Q000166:cytology* / Q000378:metabolism; D064030:S100 Calcium Binding Protein G; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D015415:Biomarkers; D064026:Calbindins; D009419:Nerve Tissue Proteins; D064030:S100 Calcium Binding Protein G; D005680:gamma-Aminobutyric Acid; D002795:Choline O-Acetyltransferase