title: HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL.
abstract: HIV-1 genotypic resistance test results were obtained on clinical samples from 116 patients with plasma HIV-1 RNA levels of less than 75 copies/mL. Genotype validity was confirmed in 49 of 50 patients with a previous or follow-up genotype. The belief that genotypic resistance testing is unreliable in samples with low-level viremia should be reassessed.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Stanford University, Stanford 94305, and Kaiser-Permanente Medical Care Program-Northern California, Oakland, CA, USA.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Mitsuya
authors.forename: Mark A
authors.initials: MA
authors.lastname: Winters
authors.forename: W Jeffrey
authors.initials: WJ
authors.lastname: Fessel
authors.forename: Soo-Yon
authors.initials: SY
authors.lastname: Rhee
authors.forename: Sally
authors.initials: S
authors.lastname: Slome
authors.forename: Jason
authors.initials: J
authors.lastname: Flamm
authors.forename: Michael
authors.initials: M
authors.lastname: Horberg
authors.forename: Leo
authors.initials: L
authors.lastname: Hurley
authors.forename: Daniel
authors.initials: D
authors.lastname: Klein
authors.forename: Robert W
authors.initials: RW
authors.lastname: Shafer
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D024882:Drug Resistance, Viral; D005838:Genotype; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology*; D015497:HIV-1 / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D010802:Phylogeny; D012367:RNA, Viral / Q000097:blood* / Q000235:genetics* / Q000302:isolation & purification; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents; D012367:RNA, Viral