Lethal brain abscess due to the fungus Scedosporium apiospermum (teleomorph Pseudallescheria boydii) after a near-drowning incident: case report and review of the literature.
A 39-year-old healthy man developed a brain abscess weeks after a near-drowning incident. Scedosporium apiospermum, the anamorph of Pseudallescheria boydii, was isolated from the abscess. The patient died 153 days after the accident despite antifungal therapy. We discuss the role of antifungals and review the literature for comparable cases.
Buzina
W
W
Medical Mycology, Institute of Hygiene, Medical University Graz, Universitaetsplatz, Graz, Austria. walter.buzina@meduni-graz.at
Feierl
G
G
Haas
D
D
Reinthaler
F F
FF
Holl
A
A
Kleinert
R
R
Reichenpfader
B
B
Roll
P
P
Marth
E
E
D000063:Accidents, Traffic; D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D001922:Brain Abscess / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D008271:Mycetoma / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D015701:Near Drowning / Q000150:complications*; D011541:Pseudallescheria / Q000302:isolation & purification; D011743:Pyrimidines / Q000494:pharmacology / Q000627:therapeutic use; D021681:Scedosporium / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D013687:Telencephalon / Q000382:microbiology; D014230:Triazoles / Q000494:pharmacology / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole