[The effect of Medicago spp. on growth of Trichophyton mentagrophytes in microculture].
The study aimed at assessing effect of dried root and aerial parts of Medicago spp. on growth of Trichophryton mentagrophytes. Fungus strains were inoculated onto microcultures with Sabouraud agar supplemented each with 1 g of dried and pulverised roots or aerial parts of 3 species: Medicago arabica, M. sativa, and M. murex. The strongest inhibitory effect on T. mentagrophytes growth was that of aerial parts of M. arabica (median diameter 6 mm compared to 13 mm of control), followed by root of M. arabica (10 mm) and root of M. murex (10.5 mm)--in all cases p < 0.001. Slight inhibitory effect was also found in the case of aerial parts of M. murex (median diameter 12 mm, p = 0.03). In contrast, M. sativa has shown stimulating effect on growth of T. mentagrophytes (15 mm for root and 16.5 mm for aerial part, p<0.001).
Spiewak
R
R
Instytut Medycyny Wsi, ul. Jaczewskiego 2, 20-090 Lublin.
Szostak
W
W
Jurzysta
M
M
Biały
Z
Z
Maleszka
R
R
Rzepecka
B
B
Mazurek
M
M
D000935:Antifungal Agents / Q000494:pharmacology*; D029902:Medicago; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry / Q000633:toxicity; D012503:Saponins / Q000737:chemistry / Q000494:pharmacology*; D014249:Trichophyton / Q000145:classification / Q000187:drug effects* / Q000254:growth & development*
D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins