title: Oxidative DNA damage levels and catalase activity in the clam Ruditapes decussatus as pollution biomarkers of Tunisian marine environment.
abstract: Levels of the oxidative DNA damage 7, 8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG) and catalase (CAT) activity were measured in the digestive gland and gills of clams Ruditapes decussatus, related to the presence of pollutants along Tunisian marine environment. Increased levels of CAT were observed in tissues of clams from all the sites studied, compared to control values, and elevated 8-oxodG levels were observed at specific sites. Results obtained in this work indicate that the measurement of 8-oxodG levels and CAT activity in tissues of R. decussatus is promising in pollution monitoring studies of the Tunisian marine environment.
authors.affiliation: Laboratoire de Biochimie et de Toxicologie Environnementale, Ecole Supérieure d'Horticulture et d'Elevage, Chott-Marièm, 4042, Tunisia. jebali.jamel@laposte.net
authors.forename: Jamel
authors.initials: J
authors.lastname: Jebali
authors.forename: Mohamed
authors.initials: M
authors.lastname: Banni
authors.forename: Eduardo Alves
authors.initials: EA
authors.lastname: de Almeida
authors.forename: Hamadi
authors.initials: H
authors.lastname: Boussetta
mesh_terms: D000080242:8-Hydroxy-2'-Deoxyguanosine; D000818:Animals; D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D049872:Bivalvia / Q000201:enzymology / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism*; D004249:DNA Damage; D003849:Deoxyguanosine / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D004064:Digestive System / Q000201:enzymology / Q000378:metabolism; D004784:Environmental Monitoring / Q000379:methods*; D005880:Gills / Q000201:enzymology / Q000378:metabolism; D018384:Oxidative Stress; D014416:Tunisia; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000633:toxicity
chemical_list: D015415:Biomarkers; D014874:Water Pollutants, Chemical; D000080242:8-Hydroxy-2'-Deoxyguanosine; D002374:Catalase; D003849:Deoxyguanosine