[Peripheral blood lymphocytes T gammadelta in children with acute acquired toxoplasmosis].
The aim of the study was to determine the percentage participation of lymphocytes CD3TCRgammadelta in peripheral blood of children with acute toxoplasmosis. The study compromised 30 children aged 2-14 years. Increase of the percentage of CD3TCR gammadelta cells was observed in the group of children with clinical symptoms of toxoplasmosis (mean value 5.7%) in relation to the comparative group (mean 4.4%), but in 12 children (40%) the mean value was 8.1%. Toxoplasma gondii infection produces a strong signal for activation of cells with gammadelta receptors. Examination of CD3TCRgammadelta cells may be helpful in the diagnosis of the acute phase of T. gondii infection.
Kmieć
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III Klinika Pediatrii ICZMP, 93-338 Lódź, ul. Rzgowska 281/289.
Woźniakowska-Gesicka
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D000208:Acute Disease; D000293:Adolescent; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis*; D012016:Reference Values; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000276:immunology*
D016692:Receptors, Antigen, T-Cell, gamma-delta