Questioning INS VNTR role in obesity and diabetes: subclasses tag IGF2-INS-TH haplotypes; and -23HphI as a STEP (splicing and translational efficiency polymorphism).
Day
Ian N M
IN
Rodriguez
Santiago
S
Královicová
Jana
J
Wood
Peter J
PJ
Vorechovsky
Igor
I
Gaunt
Tom R
TR
D001786:Blood Glucose / Q000378:metabolism; D015252:Deoxyribonucleases, Type II Site-Specific; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics* / Q000378:metabolism; D006239:Haplotypes; D006801:Humans; D007328:Insulin / Q000235:genetics* / Q000378:metabolism; D007335:Insulin-Like Growth Factor II; D008297:Male; D018598:Minisatellite Repeats; D009765:Obesity / Q000235:genetics* / Q000378:metabolism; D011110:Polymorphism, Genetic; D014176:Protein Biosynthesis; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D012326:RNA Splicing; D014446:Tyrosine 3-Monooxygenase / Q000235:genetics
D001786:Blood Glucose; C035170:IGF2 protein, human; D007328:Insulin; D011506:Proteins; D007335:Insulin-Like Growth Factor II; D014446:Tyrosine 3-Monooxygenase; D015252:Deoxyribonucleases, Type II Site-Specific; C024412:GGTGA-specific type II deoxyribonucleases