Worsening of steroid dependent asthma : A possible role of rifampicin.
A 40-year-old male patient with chronic steroid dependent asthma developed pulmonary tuberculosis. After administration of antituberculosis therapy with rifampicin, isoniazid and pyrazinamide his asthma worsened. Omission of rifampicin from the drug regimen successfully controlled bronchospasm.
Gupta
D
D
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh-160012, India.
Yadav
S
S
Behera
D
D
Jindal
S K
SK
D000328:Adult; D000904:Antibiotics, Antitubercular / Q000009:adverse effects* / Q000627:therapeutic use; D001249:Asthma / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy; D018450:Disease Progression; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D012293:Rifampin / Q000009:adverse effects* / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy*
D000904:Antibiotics, Antitubercular; D005938:Glucocorticoids; D012293:Rifampin