title: Excitation UNFOLD (XUNFOLD) to improve the temporal resolution of multishot tailored RF pulses.
abstract: An extension of the "UNaliasing by Fourier encoding the Overlaps using the temporaL Dimension" (UNFOLD) method to the excitation domain (XUNFOLD) is presented to improve the temporal resolution of multishot tailored RF (TRF) pulses. Multishot three-dimensional TRF pulses were designed to produce a time series of images with periodically aliased excitation profiles. The XUNFOLD method is shown to remove the excitation profile aliasing from the dynamic imaging data by filtering in the temporal frequency dimension. The technique is demonstrated to improve the temporal resolution of simulated functional MRI (fMRI) activation in a time series of brain images.
authors.affiliation: Department of Medicine, University of Hawaii, Honolulu, Hawaii 96813, USA. stenger@hawaii.com
authors.forename: V Andrew
authors.initials: VA
authors.lastname: Stenger
authors.forename: Marius S
authors.initials: MS
authors.lastname: Giurgi
authors.forename: Fernando E
authors.initials: FE
authors.lastname: Boada
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Noll
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted