Use of proteomics in analysis of autoimmune diseases.
Autoimmune diseases are common by diseases characterized by disorders of immune responses and autoimmune impairment involving multiple tissues, organs and systems. The autoantigens (Ags)/autoantibodies (Abs) are not only hallmarks but also involved in pathogenesis of autoimmune diseases. In recent years, proteomics technologies have been used and demonstrated effective in searching new Ags/Abs as well as disease biomarkers in autoimmune diseases.
Xiang
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Y
Department of Bioregulation and Proteomics, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
Kato
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T
D000818:Animals; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001324:Autoantigens / Q000032:analysis / Q000276:immunology; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D040901:Proteomics / Q000379:methods*
D001323:Autoantibodies; D001324:Autoantigens