title: [Arbovirus causing hemorrhagic fever at IMSS].
abstract: OBJECTIVE
  To know the arbovirus causing hemorrhagic fever in patients at the Mexican Institute of Social Security.
  
  
  METHODS
  A follow-up study was made in patients with probable diagnosis of hemorrhagic dengue. Blood samples were taken to look for dengue fever, yellow fever and San Luis, Tonate and Mayaro encephalitis viruses. Frequencies and proportions of the interest variables were analyzed.
  
  
  RESULTS
  35 patients were studied. Isolation and PCR results of the 13 samples were negative in 12 of them and positive to denguevirus-3 in one of them. The determination of IgM was positive for dengue fever in 25 cases; 2 were positive to Mayaro virus and 8 were negative to what was looked for. Hemorrhages and thrombocytopenia were more frequent in patients infected with dengue and Mayaro viruses; jaundice and encephalopathy were more frequent in the latter, and renal dysfunction, in patients with a negative result. Evolution was satisfactory in all cases, except for one (Mayaro), which presented hemorrhages, thrombocytopenia, jaundice and encephalopathy that lead to death.
  
  
  CONCLUSIONS
  The results show the risk of appearance and dissemination of several vector-born diseases in Mexico. Thus, they require intensive epidemiological surveillance to identify them and to know their real occurrence and specific clinical profile.
authors.affiliation: Coordinación de Prgramas Integrados de Salud, Instituto Mexicano del Seguro Social. joel.navarrete@imss.gob.mx
authors.forename: Joel
authors.initials: J
authors.lastname: Navarrete-Espinosa
authors.forename: Héctor
authors.initials: H
authors.lastname: Gómez-Dantés
mesh_terms: D001102:Arbovirus Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D008800:Mexico / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D019595:Severe Dengue / Q000453:epidemiology / Q000821:virology*
chemical_list: D007075:Immunoglobulin M