title: Systemic mastocytosis: a rare entity.
abstract: An 18 year old female presented with generalized maculopapular rash and headaches. The skin and bone marrow biopsy revealed numerous mast cells which stained metachromatically with giemsa and toludine blue stains and showed positivity with CD68 and CD117 on immunohistochemistry. Her clinical presentation and laboratory findings were consistent with the diagnosis of indolent systemic mastocytosis. Because of the benign course of the disease, patient was offered only anti-histamine drugs that were quite successful in alleviating her symptoms.
authors.affiliation: Section of Haematology, Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi.
authors.forename: Naveen Naz
authors.initials: NN
authors.lastname: Syed
authors.forename: Bushra
authors.initials: B
authors.lastname: Moiz
mesh_terms: D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D034721:Mastocytosis, Systemic / Q000175:diagnosis* / Q000188:drug therapy; D014582:Urticaria Pigmentosa
chemical_list: D006633:Histamine Antagonists