title: Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein.
abstract: DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.
authors.affiliation: Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, AIST, Central 6, 1-1-1 Higashi, Tsukuba 305-8566, Japan.
authors.forename: Shu
authors.initials: S
authors.lastname: Taira
authors.forename: Yong-Zhong
authors.initials: YZ
authors.lastname: Du
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Hiratsuka
authors.forename: Kaoru
authors.initials: K
authors.lastname: Konishi
authors.forename: Tai
authors.initials: T
authors.lastname: Kubo
authors.forename: Taro Q P
authors.initials: TQ
authors.lastname: Uyeda
authors.forename: Noboru
authors.initials: N
authors.lastname: Yumoto
authors.forename: Masato
authors.initials: M
authors.lastname: Kodaka
mesh_terms: D000327:Adsorption; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry*; D001710:Biotin / Q000031:analogs & derivatives* / Q000737:chemistry; D004247:DNA / Q000302:isolation & purification*; D015342:DNA Probes; D016547:Kinesins / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D008869:Microtubule-Associated Proteins / Q000737:chemistry*; D013552:Swine
chemical_list: D001426:Bacterial Proteins; D015342:DNA Probes; D008869:Microtubule-Associated Proteins; C066114:biotin-streptavidin complex; D001710:Biotin; D004247:DNA; D016547:Kinesins