title: [Magnetic resonance imaging and spectroscopic metabolites assessment in brain cryptococcosis].
abstract: Cryptococcus neoformans is the causative agent of cryptococcosis and cryptococcal meningitis, which are serious pathological conditions affecting up to 10% of patients with AIDS. In this paper we present results magnetic resonance imaging and spectroscopic metabolites (1H MR) in brain cryptococcosis. In 1 HMR spectroscopy we find decreased metabolic ratios to nonsaturated water (H2O) signal N-acetylaspartate (NA/H2O, creatine (Cr/H20), choline (Cho/H2O). We show increased mioinositol to H2O ratio. Spectroscopy results suggest about massive neuronal injury and accompanying gliosis in brain cryptococcosis.
authors.affiliation: Klinika Obserwacyjno - Zakaźna, 15 - 540 Białystok, ul Zurawia 14.
authors.forename: A
authors.initials: A
authors.lastname: Wiercińska-Drapało
authors.forename: E
authors.initials: E
authors.lastname: Tarasow
mesh_terms: D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism* / Q000382:microbiology; D001923:Brain Chemistry; D002552:Cerebral Ventricles / Q000473:pathology* / Q000503:physiopathology; D003287:Contrast Media / Q000737:chemistry; D003401:Creatine / Q000378:metabolism*; D003453:Cryptococcosis / Q000175:diagnosis* / Q000378:metabolism*; D005911:Gliosis / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D010725:Phosphocreatine / Q000032:analysis
chemical_list: D003287:Contrast Media; D010725:Phosphocreatine; D003401:Creatine