title: Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men.
abstract: OBJECTIVE
  To clarify the effects of walking with a pedometer on metabolic parameters, including adiponectin (APN).
  
  
  METHODS
  We recruited 44 male Japanese volunteers (age, 37 +/- 9 yrs; body mass index (BMI), 24.2 +/- 2.9 kg/m2; fasting plasma glucose (FPG), 96 +/- 11 mg/dL; total cholesterol (TC) 190 +/- 26 mg/dL; triglycerides (TG) 119 +/- 80 mg/dL; HDL-C56 +/- 14 mg/dL). Subjects were instructed to walk with a pedometer and record the number of steps they walked every day for 50 days. Serum adiponectin (APN) levels were measured by enzyme immunoassay. Treatment effects were examined by Wilcoxon's rank test.
  
  
  RESULTS
  The average number of steps was 8211 +/- 2084 per day. There were significant reductions in BMI, sBP, TG and TNF-alpha levels after 50 days, but no changes in adiponectin levels. We then divided the subjects into 2 groups according to the steps walked per day, namely, more than 8000 steps (MT group, n = 22) and less than 8000 steps (LT group, n = 22) and found that the reduction in TG and BP was observed only in the MT group.
  
  
  CONCLUSIONS
  Walking with a pedometer is effective for improving metabolic parameters, such as TG and blood pressure, but is not sufficient to increase adiponectin levels in Japanese men.
authors.affiliation: Department of Lifestyle-related disease, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. junji@med.kanazawa-u.ac.jp
authors.forename: Junji
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Murase
authors.forename: Akimichi
authors.initials: A
authors.lastname: Asano
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nohara
authors.forename: Masa-aki
authors.initials: MA
authors.lastname: Kawashiri
authors.forename: Akihiro
authors.initials: A
authors.lastname: Inazu
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamagishi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mabuchi
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000273:Adipose Tissue; D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D015444:Exercise; D006801:Humans; D007564:Japan; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000378:metabolism; D016138:Walking
chemical_list: D052242:Adiponectin; D008055:Lipids; D014280:Triglycerides