title: Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics.
authors.affiliation: Department of Chemistry and Antiinfectives and Natural Products, Bayer HealthCare AG Pharmaceutical Research, AiCuris GmbH & Co. KG, Aprather Weg, 42096 Wuppertal, Germany.
authors.forename: Berthold
authors.initials: B
authors.lastname: Hinzen
authors.forename: Siegfried
authors.initials: S
authors.lastname: Raddatz
authors.forename: Holger
authors.initials: H
authors.lastname: Paulsen
authors.forename: Thomas
authors.initials: T
authors.lastname: Lampe
authors.forename: Andreas
authors.initials: A
authors.lastname: Schumacher
authors.forename: Dieter
authors.initials: D
authors.lastname: Häbich
authors.forename: Veronica
authors.initials: V
authors.lastname: Hellwig
authors.forename: Jordi
authors.initials: J
authors.lastname: Benet-Buchholz
authors.forename: Rainer
authors.initials: R
authors.lastname: Endermann
authors.forename: Harald
authors.initials: H
authors.lastname: Labischinski
authors.forename: Heike
authors.initials: H
authors.lastname: Brötz-Oesterhelt
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000648:ultrastructure; D002626:Chemistry, Pharmaceutical; D018360:Crystallography, X-Ray; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D047630:Depsipeptides
chemical_list: D000900:Anti-Bacterial Agents; D010456:Peptides, Cyclic; C585143:acyldepsipeptides; D047630:Depsipeptides