title: [Eye movement in patients with schizophrenia].
abstract: To clarify the cognitive function of schizophrenia, the exploratory eye movement was investigated using S-shaped figures in patients with schizophrenia and their relatives. As a result, the exploratory eye movement has been found to be a biological marker that reflects a specific and trait factor of schizophrenia. Using the exploratory eye movement combined with brain functional imaging, the pathology of schizophrenia that the neural network centering on thalamus was damaged is being clarified. Moreover, the disease gene of schizophrenia may be discovered especially on the chromosome 22 using the exploratory eye movement as an endophenotype. In addition, the exploratory eye movement can be given as a powerful candidate of diagnostic tool for schizophrenia.
authors.forename: Eisuke
authors.initials: E
authors.lastname: Matsushima
authors.forename: Takuya
authors.initials: T
authors.lastname: Kojima
mesh_terms: D000328:Adult; D015415:Biomarkers; D002892:Chromosomes, Human, Pair 22; D003071:Cognition; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D009415:Nerve Net / Q000473:pathology; D012559:Schizophrenia / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D012565:Schizophrenic Psychology; D013788:Thalamus / Q000473:pathology
chemical_list: D015415:Biomarkers