title: The MM2-cortical form of sporadic Creutzfeldt-Jakob disease presenting with visual disturbance.
abstract: A subclass of sporadic Creutzfeldt-Jakob disease (sCJD) characterized by onset with visual symptoms (Heidenhain variant) has been reported to belong to the MM1 or MV1 type according to Parchi's classification. The authors report a 65-year-old woman with MM2-cortical sCJD with slowly progressive visual disturbance as the initial symptom. Diffusion-weighted MRIs revealed hyperintensity in both occipital cortices at an early stage.
authors.affiliation: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan. ichi51@med.kanazawa-u.ac.jp
authors.forename: I
authors.initials: I
authors.lastname: Nozaki
authors.forename: T
authors.initials: T
authors.lastname: Hamaguchi
authors.forename: M
authors.initials: M
authors.lastname: Noguchi-Shinohara
authors.forename: K
authors.initials: K
authors.lastname: Ono
authors.forename: H
authors.initials: H
authors.lastname: Shirasaki
authors.forename: K
authors.initials: K
authors.lastname: Komai
authors.forename: T
authors.initials: T
authors.lastname: Kitamoto
authors.forename: M
authors.initials: M
authors.lastname: Yamada
mesh_terms: D000368:Aged; D007562:Creutzfeldt-Jakob Syndrome / Q000145:classification / Q000150:complications* / Q000235:genetics; D004252:DNA Mutational Analysis; D005260:Female; D006801:Humans; D014786:Vision Disorders / Q000209:etiology*