title: Glycosylated foldamers to probe the carbohydrate-carbohydrate interaction.
abstract: The synthesis of a triglycosylated helical foldamer based on a combination of cyclopentyl- and pyrrolidinyl-based amino acids is described. This structure is stable in water, maintaining as it does a series of carbohydrate units in proximity to one another, and represents the basis of a new approach to the study of carbohydrate-carbohydrate interactions.
authors.affiliation: School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
authors.forename: Graham L
authors.initials: GL
authors.lastname: Simpson
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Gordon
authors.forename: David M
authors.initials: DM
authors.lastname: Lindsay
authors.forename: Netnepa
authors.initials: N
authors.lastname: Promsawan
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Crump
authors.forename: Keith
authors.initials: K
authors.lastname: Mulholland
authors.forename: Barry R
authors.initials: BR
authors.lastname: Hayter
authors.forename: Timothy
authors.initials: T
authors.lastname: Gallagher
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D006031:Glycosylation; D008958:Models, Molecular; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry*; D017510:Protein Folding
chemical_list: D002241:Carbohydrates; D010455:Peptides