False recognition of incidentally learned pictures and words in primary progressive aphasia.
Recognition memory was tested in patients with primary progressive aphasia (PPA), a language based dementia with relative preservation of memory for at least the first 2 years. The goal of the study was two-fold: (1) to compare true and false recognition rates for words versus pictures in patients with PPA and cognitively intact controls and (2) to determine if the semantic relatedness of distracters-to-targets influences recognition memory performance. Overall, performance of PPA patients was worse for words than pictures. PPA patients and healthy elderly controls showed similar recognition rates for studied items. However, the patients had significantly more false alarms than controls, particularly to semantically related items. This suggests that the aphasia in PPA patients contributes to their difficulty in selecting among items within a semantic class.
Rogalski
Emily
E
Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, IL, USA. e-rogalski@northwestern.edu
Blum
Diana
D
Rademaker
Alfred
A
Weintraub
Sandra
S
D000368:Aged; D018888:Aphasia, Primary Progressive / Q000523:psychology*; D005260:Female; D006801:Humans; D007858:Learning / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011578:Psycholinguistics; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D011932:Reading; D021641:Recognition, Psychology / Q000502:physiology*; D017603:Signal Detection, Psychological / Q000502:physiology; D014796:Visual Perception / Q000502:physiology