title: [Basal insulin levels in a Zulia State population in Venezuela].
abstract: This study examines the basal insulin levels in a population from Zulia state (Venezuela). A total of 1703 subjects (1175 women and 528 men) from five different sanitary regions (Maracaibo, La Guajira, Perijá, Sur del Lago de Maracaibo, y Costa Oriental del Lago de Maracaibo) were studied. Weight, height, waist and hip circumferences, and blood pressure were determined. A blood sample was taken after a 12-h overnight fast to determine serum glucose, triglycerides, total cholesterol and HDL-C using enzymatic methods and insulin by radioimmunoassay. According to ATP III criteria two groups were established: a group without metabolic abnormalities (138 subjects) and a group with some metabolic abnormalities 84.8% of subjects of the non metabolic alteration groups and 80.4% of the group with some metabolic alteration were of mixed race. Non metabolic altered lean subjects (BMI <25 Kg/m2) had the lowest (p < 0.0001) basal insulin levels compared to the ones with overweight from the same group and the obese with metabolic abnormalities. This study proposes to consider a cutoff basal insulin levels of 13 microU/mL for women and 11 microU/mL for men, over 20 years of age, in the Zulia state region of Venezuela.
authors.affiliation: Instituto de Investigaciones Clínicas Dr. Américo Negrette, Facultad de Medicina, Universidad del Zulia, Apartado 23 Maracaibo, Venezuela. vfernandez@luz.edu.ve
authors.forename: Virginia
authors.initials: V
authors.lastname: Fernández
authors.forename: Emilio
authors.initials: E
authors.lastname: Clavell
authors.forename: José J
authors.initials: JJ
authors.lastname: Villasmil
authors.forename: Gustavo
authors.initials: G
authors.lastname: Calmón
authors.forename: Xiomara
authors.initials: X
authors.lastname: Raleigh
authors.forename: Luz Marina
authors.initials: LM
authors.lastname: Morales
authors.forename: Gilberto
authors.initials: G
authors.lastname: Campos
authors.forename: Elena
authors.initials: E
authors.lastname: Ryder
authors.forename: Eglee
authors.initials: E
authors.lastname: Silva
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005006:Ethnicity; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood; D050177:Overweight; D012016:Reference Values; D013851:Thinness / Q000097:blood; D014280:Triglycerides / Q000097:blood; D014687:Venezuela
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D007328:Insulin; D014280:Triglycerides; D002784:Cholesterol