Cancer-associated genodermatoses: a personal history.
Cancer-associated genodermatoses are a group of genetic disorders inherited in an autosomal-dominant fashion in which unique cutaneous findings are a reliable marker for the risk of developing internal malignancies. The historical, clinical and dermatopathological aspects of basal cell nevus syndrome, Muir-Torre syndrome, Cowden syndrome, Carney complex and Birt-Hogg-Dubé syndrome are reviewed in a personal and informal fashion. The latest advances in the molecular genetics of the disorders are also summarized.
Burgdorf
Walter H C
WH
Department of Dermatology, Ludwig Maximilian University, Munich, Germany. wburgdorf@gmx.de
D001478:Basal Cell Nevus Syndrome / Q000175:diagnosis / Q000503:physiopathology; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis* / Q000503:physiopathology; D012867:Skin / Q000473:pathology; D012873:Skin Diseases, Genetic / Q000175:diagnosis* / Q000503:physiopathology