[Retinal changes in patients with familial adenomatous polyposis].
OBJECTIVE
The aim of study was to evaluate retinal changes in patients diagnosed with familial adenomatous polyposis (FAP) and in patients with family history of FAP.


METHODS
The study was conducted on 51 patients diagnosed with FAP and 35 subjects with family history of FAP.


RESULTS
In 44 patients diagnosed with FAP (86.2%), typical pigmentation of fundus lesions were observed, in 1 patient atypical fundus changes were evident. However, in the group of patients with family history of FAP, the presence of typical fundus lesions was observed in 9 patients (25.7%). In the period of at least 6 month observation, no changes in fundus lesions were present in both groups.


CONCLUSIONS
The occurrence of retinal changes typical for FAP, especially in patients with family history of the disease, should imply the higher risk of FAP.
Cymerys
Elibieta
E
Katedry i Kliniki Okulistyki Akademii Medycznej w Poznaniu.
Pecold
Krystyna
K
Paszkowski
Jacek
J
Banasiewicz
Tomasz
T
Krokowicz
Piotr
P
D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000235:genetics*; D012171:Retinal Vessels / Q000473:pathology