PACAP receptor (PAC1-R) expression in rat and rhesus monkey thymus.
The expression of PACAP receptor (PAC1-R) was investigated in the thymus of rats and rhesus monkeys. In the rat thymus, PAC1-R positive cells were found in the intermediate type of thymic epithelial cells of the medulla. PAC1-R-positive cells were also seen in the thymic medulla of the rhesus monkey. The thymus showed unusual structures in some rhesus monkey dams (F0) and offspring (F1) exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Additionally, in these rhesus monkeys, PAC1-R expression was different from that in the control thymus.
Tokuda
N
N
Department of Anatomy, Department of Human Science, Yamaguchi University School of Medicine, Ube 755-8505, Japan. toku@yamaguchi-u.ac.jp
Arudchelvan
Y
Y
Sawada
T
T
Adachi
Y
Y
Fukumoto
T
T
Yasuda
M
M
Sumida
H
H
Shioda
S
S
Fukuda
T
T
Arima
A
A
Kubota
S
S
D000818:Animals; D007150:Immunohistochemistry; D008253:Macaca mulatta; D051381:Rats; D051237:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I / Q000378:metabolism*; D013950:Thymus Gland / Q000378:metabolism
D051237:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I