title: Impact of Helicobacter pylori on the management of dyspepsia in primary care.
abstract: BACKGROUND
  It is unclear what impact Helicobacter pylori infection has had on the management of dyspepsia in primary care and to what extent published guidelines on H. pylori are implemented in routine clinical practice.
  
  
  OBJECTIVE
  To assess the impact of H. pylori infection on the management of dyspepsia in primary care.
  
  
  METHODS
  Patients referred by primary care doctors to an open-access 13-carbon urea breath test service over a 2-year period for their first urea breath test were included in the study. Individual breath results were linked with data on prescribing obtained from the General Medical Services prescription database.
  
  
  RESULTS
  Of 805 patients, 374 (47%) had a positive urea breath test and 431 (54%) a negative urea breath test. Of positive urea breath test patients, only 245 (64%) were prescribed eradication therapy in the 3 months after the breath test and only 43% were referred back for re-testing. In the year after the urea breath test, there was a significant fall in prescribing of antisecretory therapy which was greatest in the patients who received H. pylori therapy (P < 0.001).
  
  
  CONCLUSIONS
  There appears to be under and inappropriate treatment of H. pylori infection in primary care, and a low rate of re-testing after eradication, indicating that current guidelines are not well implemented in practice.
authors.affiliation: Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland. bennettk@tcd.ie
authors.forename: K
authors.initials: K
authors.lastname: Bennett
authors.forename: J
authors.initials: J
authors.lastname: Feely
authors.forename: O
authors.initials: O
authors.lastname: Thornton
authors.forename: M
authors.initials: M
authors.lastname: Dobson
authors.forename: C A
authors.initials: CA
authors.lastname: O'Morain
authors.forename: H J
authors.initials: HJ
authors.lastname: O'Connor
mesh_terms: D000328:Adult; D000863:Antacids / Q000627:therapeutic use*; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D004415:Dyspepsia / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D019983:Guideline Adherence; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D011320:Primary Health Care / Q000592:standards
chemical_list: D000863:Antacids