title: [18F]fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease.
abstract: Takayasu's arteritis (TA) is a rare disease that can be difficult to diagnose in its early stage. A young woman with a fever and neck pain was thought to have TA, although computed tomographic angiography did not show any specific changes of the arteries. [(18)F]fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) was performed to detect the source of the inflammation. Specific accumulation of [(18)F]FDG-6-phosphate in the thoracic aorta and its direct branches was observed, leading to a diagnosis of TA. [(18)F]FDG-PET is therefore considered to be useful for the diagnosis of early-stage TA.
authors.affiliation: Department of Internal Medicine, Rheumatology, Infectious Disease and Laboratory Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-0012, Japan.
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Umekita
authors.forename: Ichiro
authors.initials: I
authors.lastname: Takajo
authors.forename: Syunichi
authors.initials: S
authors.lastname: Miyauchi
authors.forename: Katoko
authors.initials: K
authors.lastname: Tsurumura
authors.forename: Siro
authors.initials: S
authors.lastname: Ueno
authors.forename: Norio
authors.initials: N
authors.lastname: Kusumoto
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Kai
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kuroki
authors.forename: Takashi
authors.initials: T
authors.lastname: Sasaki
authors.forename: Akihiko
authors.initials: A
authors.lastname: Okayama
mesh_terms: D000293:Adolescent; D017023:Coronary Angiography; D042241:Early Diagnosis; D005260:Female; D005335:Fever of Unknown Origin / Q000000981:diagnostic imaging / Q000503:physiopathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D012720:Severity of Illness Index; D013348:Subclavian Artery / Q000000981:diagnostic imaging; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18