title: Experimental training model of pancreas transplant.
abstract: Pancreas transplant (Ptx) is the gold standard for the treatment of type I diabetes, mainly when associated with renal failure. The number of Ptx is increasing worldwide, but in developing countries, such as Brazil, the number of centers is small and transplant surgeons need to practice the technique.
  
  
  METHODS
  For this model, 21 pancreas harvestings were performed in patient corpses after death from extra-abdominal causes, without pancreatic disease and peritoneal or systemic infection. The vessels of the grafts were prepared on the backtable according to the usual practice in humans. The pancreas was implanted in the inferior vena cava and aorta of mixed breed dogs, with 10 exocrine-bladder drainage and 11 duodenum-ileal anastomosis.
  
  
  RESULTS
  There were anastomotic strictures of the portal vein in dogs 1 and 2. There was no arterial stricture or large bleeding. None of the animals died until the revascularization of the graft. Dogs 2, 5, and 8 died during the exocrine anastomosis. The arterial flow was initially high, but at the end of the procedure there were thromboses of small arteries.
  
  
  CONCLUSIONS
  The experimental surgical technique model is feasible, repeating the stages of clinical pancreatic transplantation and allowing the training of surgeons.
authors.affiliation: Surgery Department, Santa Casa of São Paulo, São Paulo, Brazil. andredavid@medscape.com
authors.forename: A I
authors.initials: AI
authors.lastname: David
authors.forename: C G
authors.initials: CG
authors.lastname: Aquino
authors.forename: L R
authors.initials: LR
authors.lastname: Guidoni
authors.forename: A
authors.initials: A
authors.lastname: Moricz
authors.forename: E
authors.initials: E
authors.lastname: David-Neto
authors.forename: A M
authors.initials: AM
authors.lastname: Pacheco
authors.forename: L A
authors.initials: LA
authors.lastname: Szutan
mesh_terms: D000818:Animals; D002102:Cadaver; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D004285:Dogs; D006801:Humans; D023421:Models, Animal; D016035:Pancreas Transplantation / Q000193:education* / Q000379:methods; D020858:Tissue and Organ Harvesting / Q000193:education* / Q000379:methods