title: Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers.
authors.affiliation: Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2100 Copenhagen, Denmark.
authors.forename: Christian A
authors.initials: CA
authors.lastname: Olsen
authors.forename: Ian R
authors.initials: IR
authors.lastname: Mellor
authors.forename: Petrine
authors.initials: P
authors.lastname: Wellendorph
authors.forename: Peter N R
authors.initials: PN
authors.lastname: Usherwood
authors.forename: Matthias
authors.initials: M
authors.lastname: Witt
authors.forename: Henrik
authors.initials: H
authors.lastname: Franzyk
authors.forename: Jerzy W
authors.initials: JW
authors.lastname: Jaroszewski
mesh_terms: D006801:Humans; D015640:Ion Channel Gating; D018733:Nicotinic Antagonists / Q000737:chemistry* / Q000633:toxicity*; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000633:toxicity; D011073:Polyamines / Q000737:chemistry* / Q000633:toxicity*; D011978:Receptors, Nicotinic / Q000187:drug effects*; D014862:Wasp Venoms / Q000737:chemistry*
chemical_list: D018733:Nicotinic Antagonists; D011073:Polyamines; D011978:Receptors, Nicotinic; D014862:Wasp Venoms; C028544:cyclohexylalanine; D010649:Phenylalanine; C034092:delta-philanthotoxin