Oncogenic osteomalacia associated with an occult phosphaturic mesenchymal tumour: clinico-radiologico-pathological correlation and ultrastructural studies.
A middle-aged man presented with bone pain at multiple sites due to tumour-induced osteomalacia. The underlying occult phosphaturic mesenchymal tumour was identified by octreotide scan 5 years after presentation and confirmed by computed tomography. Tumour resection resulted in normalisation of blood chemistry and bone densitometry. Clinico-radiologico-pathological correlation and ultrastructural studies of the tumour threw light on the pathogenesis and pathophysiology of this rare disease.
Cheung
F M F
FM
Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong. fmfcheung@gmail.com
Ma
L
L
Wu
W C
WC
Siu
T H
TH
Choi
P T
PT
Tai
Y P
YP
D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D018204:Neoplasms, Connective and Soft Tissue / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D010018:Osteomalacia / Q000209:etiology*; D010710:Phosphates / Q000652:urine*; D011859:Radiography
D010710:Phosphates; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23