title: [Whether long-term use of oral contraceptives and hormone replacement therapy affects the pathology of mammary gland?].
abstract: The authors presented a retrospective analysis of the risk of using hormonal drugs in 162 women over a period of 5 years, which were operated for benign and malignant diseases of the mammary gland. For comparison we have used a control group of 100 women presenting with pathology of the mammary gland, without use of hormonal drugs, for the same period of time. The patients have been selected according to their age, parity, body weight, menarche, time of beginning of menopause, continuity of using and a daily dose of hormonal drug, history of gynecological operations, type of pathological changes in mammary gland and the range of surgical intervention for their treatment. It is proved by dispersion analysis the presence or the absence of statistical difference in the pathology of mammary gland between the studied and the control group in reference to the described risk factors.
authors.forename: Svetlozar
authors.initials: S
authors.lastname: Stoĭkov
authors.forename: Alkan
authors.initials: A
authors.lastname: Emin
authors.forename: Georgi
authors.initials: G
authors.lastname: Baĭchev
mesh_terms: D001943:Breast Neoplasms / Q000139:chemically induced* / Q000453:epidemiology / Q000473:pathology*; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000009:adverse effects*; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D003276:Contraceptives, Oral