title: T-cell costimulation--biology, therapeutic potential, and challenges.
authors.affiliation: Harvard Medical School, Boston, USA.
authors.forename: Arlene H
authors.initials: AH
authors.lastname: Sharpe
authors.forename: Abul K
authors.initials: AK
authors.lastname: Abbas
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000009:adverse effects; D061067:Antibodies, Monoclonal, Humanized; D000938:Antigen-Presenting Cells / Q000276:immunology; D018106:CD28 Antigens / Q000276:immunology*; D016207:Cytokines / Q000097:blood; D006801:Humans; D007108:Immune Tolerance; D008213:Lymphocyte Activation / Q000187:drug effects / Q000276:immunology*; D051379:Mice / Q000276:immunology; D023421:Models, Animal; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D018106:CD28 Antigens; D016207:Cytokines; C509303:TGN-1412