title: UniPep--a database for human N-linked glycosites: a resource for biomarker discovery.
abstract: There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery.
authors.affiliation: Institute for Systems Biology, Seattle, WA 98103, USA. hzhang@systemsbiology.org
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Paul
authors.initials: P
authors.lastname: Loriaux
authors.forename: Jimmy
authors.initials: J
authors.lastname: Eng
authors.forename: David
authors.initials: D
authors.lastname: Campbell
authors.forename: Andrew
authors.initials: A
authors.lastname: Keller
authors.forename: Pat
authors.initials: P
authors.lastname: Moss
authors.forename: Richard
authors.initials: R
authors.lastname: Bonneau
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Bernd
authors.initials: B
authors.lastname: Wollscheid
authors.forename: Kelly
authors.initials: K
authors.lastname: Cooke
authors.forename: Eugene C
authors.initials: EC
authors.lastname: Yi
authors.forename: Hookeun
authors.initials: H
authors.lastname: Lee
authors.forename: Elaine R
authors.initials: ER
authors.lastname: Peskind
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Richard D
authors.initials: RD
authors.lastname: Smith
authors.forename: Ruedi
authors.initials: R
authors.lastname: Aebersold
mesh_terms: D019295:Computational Biology / Q000379:methods; D030541:Databases, Genetic; D005819:Genetic Markers / Q000235:genetics*; D006020:Glycopeptides / Q000097:blood* / Q000138:chemical synthesis* / Q000235:genetics*; D006801:Humans; D013058:Mass Spectrometry
chemical_list: D005819:Genetic Markers; D006020:Glycopeptides