title: [Genetics in rheumatoid arthritis (RA)].
abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease. Genetic and environmental factors are implicated in the pathogenesis of RA. In this study we describe numerous genetic phenomena that may be implicated in the etiopathogenesis of RA i.e. antigens of major histocompatibility complex, genetic linkage analysis results of whole genome scan and polymorphism of several genes coding receptors, adhesion molecules and cytokines. Genetic background plays an important role in this disorder and is connected with multiple genes.
authors.affiliation: Uniwersytet Medyczny w Lodzi, Zakład Farmakogenetyki. jskretkowicz@pharm.am.lodz.pl
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Skretkowicz
authors.forename: K
authors.initials: K
authors.lastname: Skretkowicz-Szarmach
mesh_terms: D000818:Animals; D001172:Arthritis, Rheumatoid / Q000235:genetics*; D015815:Cell Adhesion Molecules / Q000235:genetics; D016207:Cytokines / Q000235:genetics; D008040:Genetic Linkage; D006801:Humans; D008285:Major Histocompatibility Complex / Q000235:genetics; D011110:Polymorphism, Genetic
chemical_list: D015815:Cell Adhesion Molecules; D016207:Cytokines