The hidden value of missing genotypes.
Robotic systems allow vast genetic data sets to be generated automatically with little manual input, raising questions about accuracy. To test whether errors occur randomly, I used the frequencies of missing genotypes in a large human data set to construct a population tree. Remarkably, the gaps appear to carry as strong a phylogenetic signal as the actual data themselves.
Amos
William
W
D003625:Data Collection; D030541:Databases, Genetic; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats; D010802:Phylogeny; D044382:Population Groups; D012107:Research Design