title: Cystic meningioangiomatosis.
abstract: A case of cerebral meningioangiomatosis with rare cyst formation is reported. A 14-year-old boy without any stigmata of neurofibromatosis type 2 presented intractable complex partial and generalized seizures since the age of 12 years. Neuroradiological studies showed an abnormal cystic mass with calcification in the left frontal lobe of the cerebrum. The tumor was located in the leptomeninges and cerebral cortex. The patient underwent surgical treatment because medical treatment with phenytoin and sodium valproate was not sufficient to control the seizures. An intraoperative electrocorticogram revealed that epileptic foci were recorded from the cortex, which was adjacent to the lesion. Histopathology showed specific features of meningioangiomatosis with meningioma-like nodules. The patient did not have any seizures with anticonvulsants after surgery. It is important to distinguish meningioangiomatosis from other possible cortical lesions and epileptic foci should be carefully considered before resection, because it is a benign and surgically manageable cause of seizures.
authors.affiliation: Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan. hiro-ko@med.hokudai.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Ishii
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Murata
authors.forename: Hisatoshi
authors.initials: H
authors.lastname: Saito
authors.forename: Kanako C
authors.initials: KC
authors.lastname: Kubota
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nagashima
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Iwasaki
mesh_terms: D000293:Adolescent; D000798:Angiomatosis / Q000175:diagnosis / Q000601:surgery*; D001927:Brain Diseases / Q000175:diagnosis / Q000601:surgery*; D002540:Cerebral Cortex / Q000601:surgery*; D004569:Electroencephalography; D006801:Humans; D008297:Male; D008578:Meninges / Q000601:surgery*; D012640:Seizures / Q000188:drug therapy / Q000209:etiology / Q000601:surgery