title: Evaluation of palatal saliva flow rate and oral manifestations in patients with Sjögren's syndrome.
abstract: OBJECTIVE
  The purpose of this study was to describe the oral properties of Sjögren's syndrome (SS), including the determination of palatal saliva (PS) flow rate.
  
  
  METHODS
  Forty-nine SS patients and 43 healthy controls participated. Subjective symptoms were recorded and clinical assessments of the oral mucosal, dental and periodontal status were made. Unstimulated whole saliva (WS) and PS flow rates, the number of decayed, missing and filled teeth (DMF-T number), the gingival bleeding index (GBI) and the periodontal probing depth (PPD) were determined.
  
  
  RESULTS
  Despite the decrease in the flow rate of WS in SS patients, PS was not different from those of the controls (1.57 +/- 1.02 and 1.35 +/- 2.5 microl cm(-2) min(-1), respectively). GBI (20.0% vs. 10.5%, respectively), DMF-T (27.1 +/- 6.12 vs. 23.0 +/- 6.99, respectively) and PPD (2.28 +/- 1.09 mm vs. 1.82 +/- 0.73 mm, respectively) were higher in SS compared with the controls (P < 0.05). DMF-T and PPD showed a positive correlation with anti-SSA and/or anti-SSB antibody positivity in the serum (P < 0.05).
  
  
  CONCLUSIONS
  Data of the present study suggest that the subjective feeling of xerostomia in SS patients is the result of a decrease in the volume of the whole saliva, and not of the viscous PS. Correlation of DMF-T and PPD with autoantibody positivity reveals that the oral health status of SS patients may be associated with the general autoimmune process.
authors.affiliation: Department of Prosthodontics, Faculty of Dentistry, Semmelweis University, Budapest, Hungary. krisz@fok.usn.hu
authors.forename: K
authors.initials: K
authors.lastname: Márton
authors.forename: I
authors.initials: I
authors.lastname: Boros
authors.forename: G
authors.initials: G
authors.lastname: Varga
authors.forename: T
authors.initials: T
authors.lastname: Zelles
authors.forename: P
authors.initials: P
authors.lastname: Fejérdy
authors.forename: M
authors.initials: M
authors.lastname: Zeher
authors.forename: G
authors.initials: G
authors.lastname: Nagy
mesh_terms: D000328:Adult; D000368:Aged; D001324:Autoantigens / Q000032:analysis; D004245:DMF Index; D004812:Epidemiologic Methods; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology; D009909:Oral Health; D010159:Palate / Q000378:metabolism; D012261:Ribonucleoproteins / Q000032:analysis; D012469:Salivary Glands / Q000503:physiopathology; D012472:Salivation; D012859:Sjogren's Syndrome / Q000150:complications / Q000503:physiopathology*; D014987:Xerostomia / Q000209:etiology / Q000503:physiopathology; D000097585:SS-B Antigen; D000099207:SS-A Antigen
chemical_list: D001324:Autoantigens; D012261:Ribonucleoproteins; D000097585:SS-B Antigen; D000099207:SS-A Antigen