[Characteristics of phenotypic specific and intraspecific features of fungal strains isolated from the organ ontocenoses in patients after renal transplantation].
Characteristics of phenotypic specific and intraspecific features of fungal strains isolated from the organ ontocenoses in patients after renal transplantation. The aim of present study was to describe 60 specific and intraspecific features of fungal strains isolated from the organ ontocenoses: oral cavity, rectum and genital organs in 32 patients undergoing permanent immunosupression after renal transplantation. Fungal strains identified using API 20 C and API 20 C AUX (bioMérieux). The activity of 19 hydrolases was investigated using API ZYM. Among 41 strains of fungi the following were found: Candida albicans (31 strains), C. glabrata (5), C. guilliermondii (2), C. krusei (2) and Saccharomyces cerevisiae (1). The number of fungal strains isolated from the oral cavity was the highest (21), less numerous from rectum (12) and the least from the genital organs (8). The enzymograms were described for all strains and the highest activity was noted in case of: e6 - leucine arylamidase, e11 - phosphatase acid, e3 - esterase (C4), e12 - naphtol-AS-BI-phosphohydrolase. The activity of these enzymes is connected with higher pathogenicity of C. albicans strains.
Kurnatowska
Alicja
A
Katedra Biologii i Parazytologii Lekarskiej, Uniwersytet Medyczny, al. Kokciuszki 85, 90-436 Lódź. katbiol@poczta.onet.pl
Kurnatowska
Ilona
I
Kacprzyk
Feliks
F
Chrzanowski
Witold
W
D000328:Adult; D002175:Candida / Q000145:classification / Q000302:isolation & purification; D005260:Female; D005658:Fungi / Q000145:classification* / Q000302:isolation & purification; D005835:Genitalia / Q000382:microbiology*; D006801:Humans; D006867:Hydrolases / Q000145:classification / Q000378:metabolism; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D016533:Mycological Typing Techniques; D009181:Mycoses / Q000453:epidemiology / Q000469:parasitology*; D012007:Rectum / Q000382:microbiology*; D013045:Species Specificity
D007166:Immunosuppressive Agents; D006867:Hydrolases