Skeletal diversity construction via a branching synthetic strategy.
A branching synthetic strategy was used to efficiently generate structurally diverse scaffolds, which span a broad area of chemical descriptor space, and their biological activity against MRSA was demonstrated.
Wyatt
Emma E
EE
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Fergus
Suzanne
S
Galloway
Warren R J D
WR
Bender
Andreas
A
Fox
David J
DJ
Plowright
Alleyn T
AT
Jessiman
Alan S
AS
Welch
Martin
M
Spring
David R
DR
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D016106:Methicillin Resistance; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents