title: Vaccine improves survival in monkey tests.
abstract: A vaccine tested at the U.S. NIAID clearly improved the survival of monkeys, a benefit not predicted by T-cell and viral load tests. It was predicted by measurements of memory T cells in the first few months of infection--giving important insights into how HIV disease develops, and how to test HIV vaccines early so that only the best candidates will go into large human trials.
authors.forename: John S
authors.initials: JS
authors.lastname: James
mesh_terms: D000818:Animals; D000882:Haplorhini; D007156:Immunologic Memory; D018655:Lymphocyte Count; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000628:therapy*; D015302:Simian Immunodeficiency Virus / Q000276:immunology; D015996:Survival Rate; D019562:Viral Load; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000276:immunology / Q000627:therapeutic use
chemical_list: D014765:Viral Vaccines