title: Childhood growth and chronic disease: evidence from countries undergoing the nutrition transition.
abstract: Evidence is accumulating that the pattern of growth in childhood is associated with development of cardiovascular disease in adulthood, but such evidence comes mostly from developed countries. We conducted a review of studies from countries undergoing the nutrition transition. Five birth cohorts with measures of child growth and outcomes through adolescence were identified, from China, India, Guatemala, Brazil and the Philippines. Across studies there are major differences in data availability and in statistical approaches to modelling child growth and its effects. Nevertheless, generally consistent associations of growth failure in early childhood and development of overweight in later childhood with the risk of elevated blood pressure, glucose, and serum lipids in adulthood were observed. As these cohorts mature they will provide a wealth of critical information on the relation between early life factors and later disease risk, and efforts should be made to ensure ongoing follow-up using standardized approaches and more comprehensive assessments.
authors.affiliation: Department of Global Health, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA. aryeh.stein@emory.edu
authors.forename: Aryeh D
authors.initials: AD
authors.lastname: Stein
authors.forename: Angela M
authors.initials: AM
authors.lastname: Thompson
authors.forename: Ashley
authors.initials: A
authors.lastname: Waters
mesh_terms: D000293:Adolescent; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D002908:Chronic Disease; D015331:Cohort Studies; D003906:Developing Countries; D005500:Follow-Up Studies; D006128:Growth / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D044342:Malnutrition / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control; D009765:Obesity / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control; D011446:Prospective Studies; D011634:Public Health; D012307:Risk Factors