Breaching the great wall: peptidoglycan and microbial interactions.
Once thought to be a process that occurred only in a few human pathogens, release of biologically active peptidoglycan fragments during growth by Gram-negative bacteria controls many types of bacterial interaction, including symbioses and interactions between microorganisms. This Perspective explores the role of peptidoglycan fragments in mediating a range of microbial-host interactions, and discusses the many systems in which peptidoglycan fragments released during bacterial growth might be active.
Cloud-Hansen
Karen A
KA
Department of Plant Pathology, University of Wisconsin, 1630 Linden Drive, Madison, Wisconsin 53706, USA.
Peterson
S Brook
SB
Stabb
Eric V
EV
Goldman
William E
WE
McFall-Ngai
Margaret J
MJ
Handelsman
Jo
J
D000818:Animals; D002473:Cell Wall / Q000737:chemistry / Q000378:metabolism*; D003603:Cytotoxins / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000378:metabolism* / Q000472:pathogenicity; D016905:Gram-Negative Bacterial Infections / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D010457:Peptidoglycan / Q000235:genetics / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology; D013559:Symbiosis
D003603:Cytotoxins; D010457:Peptidoglycan