title: Laterality in persons with intellectual disability II. Hand, foot, ear, and eye laterality in persons with Trisomy 21 and Williams-Beuren syndrome.
abstract: Laterality (hand, foot, ear, and eye) was assessed in participants with Trisomy 21 (62) and Williams-Beuren syndrome (WBS) (39). Handedness was also assessed in a card reaching task. The comparison group included 184 typically developing persons. Two independent age sub-groups were formed: 7 to 10 years old and 11 to 34 years old. We confirmed previous data: individuals with T21 were more frequently left- or mixed-handed than typically developing persons; individuals with WBS had intermediate scores. The two groups with genetic disorders had less right foot preference. Manual and foot inconsistencies characterized both groups with genetic disorders. Cross hand-foot preference was lower in the typically developing group. Differences in IQ levels did not correlate with differences in laterality scores. Overall laterality profiles were not the same in the two groups with genetic disorders: the greatest differences were observed between typically developing persons and persons with Trisomy 21.
authors.affiliation: Centre de Recherche PsyCLE EA3273, Aix Marseille 1, France. aude.gerard2@wanadoo.fr
authors.forename: Aude
authors.initials: A
authors.lastname: Gérard-Desplanches
authors.forename: Christine
authors.initials: C
authors.lastname: Deruelle
authors.forename: Silvia
authors.initials: S
authors.lastname: Stefanini
authors.forename: Catherine
authors.initials: C
authors.lastname: Ayoun
authors.forename: Virginia
authors.initials: V
authors.lastname: Volterra
authors.forename: Stefano
authors.initials: S
authors.lastname: Vicari
authors.forename: Gene
authors.initials: G
authors.lastname: Fisch
authors.forename: Michèle
authors.initials: M
authors.lastname: Carlier
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002755:Choice Behavior; D023882:Dominance, Ocular / Q000235:genetics*; D004314:Down Syndrome / Q000235:genetics* / Q000523:psychology; D005260:Female; D007839:Functional Laterality / Q000235:genetics*; D006801:Humans; D007360:Intelligence / Q000235:genetics; D008297:Male; D009483:Neuropsychological Tests; D011597:Psychomotor Performance; D012016:Reference Values; D018980:Williams Syndrome / Q000235:genetics* / Q000523:psychology