[Activities of some enzymes and concentration of ammonia in serum of rats with fluoride hyperglycemia].
The study was done in 30 one-month-old Wistar FL rats divided into one control and two study groups of ten animals each. Hyperglycemia was induced with sodium fluoride in water at a concentration of 50 or 100 mg/L during four months. Control animals received distilled water. We observed significantly (p < 0.05) reduced activities of aspartate aminotransferase (by 22.8%) and malic dehydrogenase (by 10.9%) in the group exposed to 100 mg F(-)/L. No pathological changes were revealed in the pancreas of exposed animals.
Grucka-Mamczar
Ewa
E
Zakład Biochemii Ogólnej Katedry Biochemii w Zabrzu Slaskiej Akademii Medycznej w Katowicach ul. Jordana 19, 41-808 Zabrze.
Birkner
Ewa
E
Stawiarska-Pieta
Barbara
B
Duliban
Hanna
H
Polaniak
Renata
R
Chlubek
Dariusz
D
Samujło
Dorota
D
Cegłowska
Alicja
A
D000641:Ammonia / Q000097:blood*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D006943:Hyperglycemia / Q000097:blood* / Q000139:chemically induced* / Q000473:pathology; D008291:Malate Dehydrogenase / Q000097:blood*; D008297:Male; D010179:Pancreas / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D012969:Sodium Fluoride / Q000633:toxicity*
D000641:Ammonia; D012969:Sodium Fluoride; D008291:Malate Dehydrogenase; D001219:Aspartate Aminotransferases