title: Primary treatment of the anterior vocal commissure squamous carcinoma.
abstract: Squamous cell carcinoma may involve the anterior commissure (AC) area of the laryngeal glottis, and can be grouped morphologically into four groups; (1) tumor confined to the AC, (2) tumor involving one cord and the AC, (3) tumor involving the AC and a portion of both vocal cords, and (4) tumor involving a greater part of one cord and crossing over to involve a variable length of the other cord. Some of these patients when evaluated by imaging, either CT and/or MRI, may demonstrate thyroid cartilage erosion or involvement, thereby upstaging a T1a, T1b into a T3 or a T4 glottic cancer. The majority of patients treated by radiotherapy have only been staged clinically, and hence a failure or recurrence rate of 15%. In patients treated surgically by endoscopic or external surgery, the local recurrence rates are similar at 15%. Therefore, future reporting of patients treated with AC involvement should be staged radiologically, to include CT or MRI, and documentation of the treatment results be reported in subgroups, according to whether there is no cartilage involvement, inner-table cartilage erosion, or through-and-through cartilage invasion. Should endoscopic cordectomy be used, then the type of surgery performed should be based on the classification as suggested by the European Laryngological Society. The use of the above recommendations would allow for more meaningful results to be reported and for cause specific analysis of failure of treatment techniques applied.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Queens Medical Centre, Nottingham, UK.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Bradley
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rinaldo
authors.forename: Carlos
authors.initials: C
authors.lastname: Suárez
authors.forename: Ashok R
authors.initials: AR
authors.lastname: Shaha
authors.forename: C René
authors.initials: CR
authors.lastname: Leemans
authors.forename: Johannes A
authors.initials: JA
authors.lastname: Langendijk
authors.forename: Snehal G
authors.initials: SG
authors.lastname: Patel
authors.forename: Alfio
authors.initials: A
authors.lastname: Ferlito
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy*; D005931:Glottis / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D007828:Laryngoscopy; D014827:Vocal Cords / Q000473:pathology*