Molecular design and chemical synthesis of a highly potent epothilone.
Nicolaou
K C
KC
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu
Pratt
Benjamin A
BA
Arseniyadis
Stellios
S
Wartmann
Markus
M
O'Brate
Aurora
A
Giannakakou
Paraskevi
P
D034261:Epothilones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013329:Structure-Activity Relationship
D034261:Epothilones