Pediatric reference intervals for uncommon bleeding and thrombotic disorders.
This study provides pediatric reference intervals and median values for factors II, V, VII, X, fibrinogen, alpha-2-antiplasmin (AP), antithrombin (AT), plasminogen, protein C (PC), and protein S (PS) for children 7 to 17 years of age. All analytes exhibited at least some age dependence in late childhood and adolescence either when compared against adult values or when medians for children were regressed against age.
Flanders
Michele M
MM
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.
Phansalkar
Amit R
AR
Crist
Ronda A
RA
Roberts
William L
WL
Rodgers
George M
GM
D000293:Adolescent; D000991:Antithrombins / Q000378:metabolism; D001778:Blood Coagulation Disorders / Q000378:metabolism* / Q000503:physiopathology*; D002648:Child; D005165:Factor V / Q000378:metabolism; D005167:Factor VII / Q000378:metabolism; D005170:Factor X / Q000378:metabolism; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D010372:Pediatrics / Q000379:methods* / Q000592:standards*; D010958:Plasminogen / Q000378:metabolism; D011486:Protein C / Q000378:metabolism; D017293:Protein S / Q000378:metabolism; D011516:Prothrombin / Q000378:metabolism; D012016:Reference Values; D020246:Venous Thrombosis / Q000378:metabolism* / Q000503:physiopathology*; D000979:alpha-2-Antiplasmin / Q000378:metabolism
D000991:Antithrombins; D011486:Protein C; D017293:Protein S; D000979:alpha-2-Antiplasmin; D005165:Factor V; D005167:Factor VII; D011516:Prothrombin; D005170:Factor X; D005340:Fibrinogen; D010958:Plasminogen