title: Multiorgan resections for advanced colorectal cancer.
abstract: BACKGROUND
  A retrospective review is presented of a single institution's experience with multivisceral resections for locally-advanced colorectal cancer.
  
  
  METHODS
  Twenty-eight patients, who had undergone RO multiorgan resection, were identified from the database of a total of 1150 patients operated on for colorectal carcinoma in the years 1995-2005 at a single center. There were twelve total pelvic exenterations and 16 patients had undergone en bloc primary tumor resection with adherent organs, such as the spleen, diaphragm, pancreas, stomach, kidney, etc. The patients were followed-up according to a standard protocol.
  
  
  RESULTS
  The post-operative mortality was 7%, the average follow-up 21.6 months and the 5-year survival 45%.
  
  
  CONCLUSIONS
  Our results confirmed that, in the case of invasion of colorectal cancer to the adjacent intra-abdominal organs or structures, multiorgan resection 'offers the only chance of potentially-curative treatment.
authors.affiliation: Department of Surgery of the Thomayer's Teaching Hospital and First Faculty of Medicine, Charles University, Videnska 800, 140 59 Prague, Czech Republic. visokai@ftn.cz
authors.forename: Vladimir
authors.initials: V
authors.lastname: Visokai
authors.forename: Ludmila
authors.initials: L
authors.lastname: Lipska
authors.forename: Pavel
authors.initials: P
authors.lastname: Bergmann
authors.forename: Miroslav
authors.initials: M
authors.lastname: Levy
authors.forename: Miroslav
authors.initials: M
authors.lastname: Trubac
authors.forename: Vera
authors.initials: V
authors.lastname: Martinu
authors.forename: Sarka
authors.initials: S
authors.lastname: Svobodova
authors.forename: Stanislav
authors.initials: S
authors.lastname: Kormunda
mesh_terms: D003082:Colectomy; D015179:Colorectal Neoplasms / Q000601:surgery*; D006801:Humans; D010180:Pancreatectomy; D010385:Pelvic Exenteration; D015996:Survival Rate