Evaluation of two new immunochromatographic assays (Rapid U Legionella antigen test and SD Bioline Legionella antigen test) for detection of Legionella pneumophila serogroup 1 antigen in urine.
We evaluated two new immunochromatographic assays for their abilities to detect Legionella pneumophila serogroup 1 antigen in urine. The results were compared with those obtained by the Binax NOW urinary antigen test. The sensitivities and specificities were estimated to be 71.2% and 96.6%, respectively, for the Rapid U test; 31.5% and 98.9%, respectively, for the SD Bioline test; and 91.8% and 100%, respectively, for the Binax NOW test.
Diederen
Bram M W
BM
Laboratory of Medical Microbiology and Immunology, St Elisabeth Hospital, P.O. Box 747, 5000 AS Tilburg, The Netherlands. b.diederen@elisabeth.nl
Peeters
Marcel F
MF
D000942:Antigens, Bacterial / Q000652:urine*; D002846:Chromatography, Affinity / Q000379:methods*; D006801:Humans; D016952:Legionella pneumophila / Q000276:immunology / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D014556:Urine / Q000382:microbiology*
D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic