title: [Relationship between activity of hydrolases in fungi isolated from vagina of pregnant women and selected symptoms].
abstract: Pregnancy is considered a factor of vulvovaginal mycosis. Secretion of hydrolases is an important determinant of Candida virulence. Thus, the aim of the study was to found the relationship between activity of 19 hydrolases in fungi isolated from vagina of pregnant women and symptoms of mycosis. 251 pregnant women were examined. Samples were collected from vagina and cultured on Sabouraud media. Activity of hydrolytic enzymes was evaluated using API ZYM (bioMerieux) test Fungi were found in 20.1% of vaginal samples. Symptoms were detected in 45.8% of women. Only 32.1% of women with discharge and 26.4% with pruritus had mycosis. Out of the 19 examined hydrolazes, 13 active enzymes were detected in fungal strains. We found for the first time the relationship between activity of fungal esterase lipase and the presence of vaginal discharge in pregnant women.
authors.affiliation: Klinika Medycyny Matczyno-Płodowej, Instytut Centrum Zdrowia Matki Polki, Rzgowska 281/289, 93-338 Lódź.
authors.forename: Dorota
authors.initials: D
authors.lastname: Nowakowska
authors.forename: Alicja
authors.initials: A
authors.lastname: Kurnatowska
authors.forename: Jan
authors.initials: J
authors.lastname: Wilczyński
mesh_terms: D002175:Candida / Q000201:enzymology* / Q000302:isolation & purification / Q000472:pathogenicity; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis* / Q000469:parasitology*; D005260:Female; D006801:Humans; D006867:Hydrolases / Q000378:metabolism*; D016533:Mycological Typing Techniques / Q000379:methods; D011044:Poland; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000469:parasitology*; D011539:Pruritus Vulvae / Q000175:diagnosis / Q000469:parasitology; D019522:Vaginal Discharge / Q000175:diagnosis / Q000469:parasitology
chemical_list: D006867:Hydrolases