Health-related quality of life in narcolepsy.
OBJECTIVE
To describe health-related quality of life in Norwegian patients with narcolepsy compared with data from the general population.


METHODS
Seventy-seven patients with narcolepsy with cataplexy were included in the final analysis. Health-related quality of life was assessed by SF-36 questionnaire.


RESULTS
Men and women with narcolepsy had lower scores in all SF-36 domains, except vitality. Most profoundly affected were bodily pain (men: p = 0.0001, women: p = 0.0001), social function (men: p = 0.0001, women: p = 0.0001) and general health (men p = 0.04, women: p = 0.0001).


CONCLUSIONS
Narcolepsy has a clear negative effect on quality of life which is not sufficiently counteracted by medical treatment. We suggest that earlier diagnosis and treatment after onset of symptoms may be important in reducing the negative effects on quality of life. Special attention should be paid to the patients social functioning and general well-being.
Ervik
S
S
Norwegian Resource Centre for ADHD, Tourette Syndrome and Narcolepsy, Ullevål University Hospital, Oslo, Norway. solveig.n.ervik@nasjkomp.no
Abdelnoor
M
M
Heier
M S
MS
Ramberg
M
M
Strand
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009290:Narcolepsy / Q000150:complications* / Q000523:psychology* / Q000628:therapy; D009664:Norway; D011788:Quality of Life; D012959:Socioeconomic Factors