title: [Clinical analysis of bladder cancer].
abstract: OBJECTIVE
  We report our clinical experiences of treatment for bladder cancer.
  
  
  METHODS
  Clinical analysis was performed about 282 primary bladder cancer patients who performed first time treatment in our hospital from January 1991 to December 2002.
  
  
  RESULTS
  As to T classification, 127 patients were in Ta, 89 in T1, 27 in T2,18 in T3, eight in T4 and 13 in Tis, respectively and among those, there were seven patients with a metastasis. Most patients of superficial cancer were treated by combined use of TUR and instillation therapy. There were few patients of total cystectomy performed as a first time treatment in the case of invasive cancer in our clinic and comparatively many preservation therapies by TUR, systemic chemotherapy and radiotherapy combined use were performed. Cancer recurred to 90 cases in 275 patients, and 18 patients died owing to cancer progression. Five and ten-years-recurrence free rate in the whole were 59.5 and 44.3%, five and ten-years-disease specific survival rate were 92.9 and 85.9%. Furthermore, 5-years-disease specific survival rate classified by T stage were 100, 100, 71.2, 46.7 (3-years-survival), 53.6, 83.3% in Ta, T1, T2, T3, T4, Tis, respectively and the significant difference was observed. The disease specific five-years survival rate of the whole local invasive carcinoma (T2-4N0M0) was 57.5% and 70.2% in the case of preservation therapy performed by TUR, chemotherapy and radiotherapy combined use.
  
  
  CONCLUSIONS
  An appropriate treatment according to the each case is needed for bladder cancer.
authors.affiliation: Department of Urology, Osaka Police Hospital.
authors.forename: Masahito
authors.initials: M
authors.lastname: Honda
authors.forename: Mototaka
authors.initials: M
authors.lastname: Satoh
authors.forename: Keiji
authors.initials: K
authors.lastname: Hasebe
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tujimoto
authors.forename: Tuyoshi
authors.initials: T
authors.lastname: Takada
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujioka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*