title: Chronic inflammatory demyelinating polyneuropathy associated with idiopathic hemochromatosis.
abstract: We describe a 50-year-old woman who developed chronic inflammatory demyelinating polyneuropathy (CIDP) one year after onset of hemochromatosis. Electrodiagnostic studies showed evidence of multifocal demyelination. Marked hypergammaglobulinemia with positive anti-nuclear and anti-DNA antibodies was found. Corticosteroid treatment resulted in a significant lessening of neurological symptoms. This is the first case of CIDP with hemochromatosis. The association may be coincidental, but the altered immune system by hemochromatosis was possibly related to the development of CIDP in this patient.
authors.affiliation: Department of Neurology, Chiba University School of Medicine, Chiba.
authors.forename: Sonoko
authors.initials: S
authors.lastname: Misawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kuwabara
authors.forename: Shinji
authors.initials: S
authors.lastname: Matsuda
authors.forename: Yumi
authors.initials: Y
authors.lastname: Sakakibara
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Jun
authors.initials: J
authors.lastname: Tashiro
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000032:analysis; D004568:Electrodiagnosis; D005260:Female; D006432:Hemochromatosis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis / Q000276:immunology; D007107:Immune System / Q000503:physiopathology; D008875:Middle Aged; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology
chemical_list: D000305:Adrenal Cortex Hormones; D000974:Antibodies, Antinuclear