title: [Pronostic value of the immunohistochemical expression of cyclin D1 (DCS6) in epidermoid larynx carcinoma].
abstract: In this paper we carried out an immunohistochemical study of cyclin D1 (DCS6 ) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain) for a time of 5 years. In the cases with lymph node metastasis we also studied cyclin D1 expression at this level. Furthermore we have analysed the value of cyclin D1 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between cyclin D1 expression and other clinic and pathologic parameters.
authors.affiliation: Servicio ORL, Hospital "Gutiérrez Ortega", Valdepeñas, Ciudad Real. cjangela@castillalmancha.es
authors.forename: M C
authors.initials: MC
authors.lastname: García Lozano
authors.forename: J L
authors.initials: JL
authors.lastname: Orradre Romero
authors.forename: S
authors.initials: S
authors.lastname: Sánchez Carrión
authors.forename: M
authors.initials: M
authors.lastname: Caro Garcia
authors.forename: O
authors.initials: O
authors.lastname: Lasso Luis
authors.forename: M A
authors.initials: MA
authors.lastname: Piris Pinilla
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism*; D019938:Cyclin D1 / Q000096:biosynthesis*; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000378:metabolism*; D011379:Prognosis
chemical_list: D019938:Cyclin D1