Degradation of carbazole and its derivatives by a Pseudomonas sp.
Carbazole, carbazoles with monomethyl or dimethyls substituted on different positions (C(1)-carbazoles or C(2)-carbazoles), and benzocarbazoles, as toxic and mutagenic components of petroleum and creosote contamination, were biodegradable by an isolated bacterial strain Pseudomonas sp. XLDN4-9. C(1)-carbazoles were degraded in preference to carbazole and C(2)-carbazoles. The biodegradation of C(1)-carbazoles or C(2)-carbazoles was influenced by the positions of methyl substitutions. Among C(1)-carbazole isomers, 1-methyl carbazole was the most susceptible. C(2)-carbazole isomers with substitutions on the same benzo-nucleus were more susceptible at a concentration of less than 3.4 microg g(-1) petroleum, especially when harboring one substitution on position 1. In particular, 1,5-dimethyl carbazole was the most recalcitrant dimethyl isomer.
Li
Li
L
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People's Republic of China.
Li
Qinggang
Q
Li
Fuli
F
Shi
Quan
Q
Yu
Bo
B
Liu
Fengrui
F
Xu
Ping
P
D001673:Biodegradation, Environmental; D018533:Biomass; D002227:Carbazoles / Q000737:chemistry / Q000378:metabolism*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009876:Operon / Q000235:genetics; D011549:Pseudomonas / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D017422:Sequence Analysis, DNA; D012988:Soil Microbiology
D002227:Carbazoles; D004269:DNA, Bacterial