Occipital condyle syndrome guiding diagnosis to metastatic prostate cancer.
Occipital condyle syndrome (OCS) results from a unilateral occipital pain associated with an ipsilateral paresis of the 12th cranial nerve (hypoglossal), and is typically caused by metastasis of the skull base. OCS diagnosis occurred, in all cases described in the published literature, when metastatic prostate cancer (MPC) was previously known. We present a case of a patient whose initial manifestation of MPC was OCS. The patient was treated with complete hormonal blockade and non-steroidal anti-inflammatory drugs as opposed to locoregional radiotherapy applied in other cases. After 18 month follow-up, the patient had a complete neurological and biochemical response.
Salamanca
Juan Ignacio Martinez
JI
Department of Urology, Hospiatal Gregorio Maranon, Madrid, Spain. msalam99@terra.es
Murrieta
Concepcion
C
Jara
Jose
J
Munoz-Blanco
Jose Luis
JL
Alvarez
Federico
F
De Villoria
Juan Guzman
JG
Hernandez
Carlos
C
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D019160:Endosonography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009777:Occipital Bone; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013577:Syndrome; D014057:Tomography, X-Ray Computed