Hearing loss in workers exposed to toluene and noise.
In this study we investigated the risk of hearing loss among workers exposed to both toluene and noise. We recruited 58 workers at an adhesive materials manufacturing plant who were exposured to both toluene and noise [78.6-87.1 A-weighted decibels; dB(A)], 58 workers exposed to noise only [83.5-90.1 dB(A)], and 58 administrative clerks [67.9-72.6 dB(A)] at the same company. We interviewed participants to obtain sociodemographic and employment information and performed physical examinations, including pure-tone audiometry tests between 0.5 and 6 kHz. A contracted laboratory certified by the Council of Labor in Taiwan conducted on-site toluene and noise exposure measurements. The prevalence of hearing loss of >or=25 dB in the toluene plus noise group (86.2%) was much greater than that in the noise-only group (44.8%) and the administrative clerks (5.0%) (p<0.001). The prevalence rates were 67.2, 32.8, and 8.3% (p<0.001), respectively, when 0.5 kHz was excluded from the estimation. Multivariate logistic regression analysis showed that the toluene plus noise group had an estimated risk for hearing loss>or=25 dB, 10.9 times higher than that of the noise-only group. The risk ratio dropped to 5.8 when 0.5 kHz was excluded from the risk estimation. Hearing impairment was greater for the pure-tone frequency of 1 kHz than for that of 2 kHz. However, the mean hearing threshold was the poorest for 6 kHz, and the least effect was observed for 2 kHz. Our results suggest that toluene exacerbates hearing loss in a noisy environment, with the main impact on the lower frequencies.
Chang
Shu-Ju
SJ
Department of Industrial Management, Aletheia University, Taipei, Taiwan.
Chen
Chiou-Jong
CJ
Lien
Chih-Hui
CH
Sung
Fung-Chang
FC
D000269:Adhesives; D000328:Adult; D001299:Audiometry; D001309:Auditory Threshold / Q000502:physiology; D003625:Data Collection; D004305:Dose-Response Relationship, Drug; D005260:Female; D034381:Hearing Loss / Q000139:chemically induced / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007221:Industry; D008297:Male; D008875:Middle Aged; D009622:Noise / Q000009:adverse effects*; D016273:Occupational Exposure / Q000009:adverse effects*; D012044:Regression Analysis; D012959:Socioeconomic Factors; D012997:Solvents / Q000009:adverse effects*; D014050:Toluene / Q000009:adverse effects*
D000269:Adhesives; D012997:Solvents; D014050:Toluene