title: [Bone metastasis of gastric cancer].
abstract: We evaluated 19 patients with bone metastasis after surgery for gastric cancer. In a number of cases, the located in the tumor was U and M region, of macroscopic 3, and the histological type was poorly-differentiated adenocarcinoma with high-grade of lymphatic invasion. The major symptom was lumbago and back pain. The serum AFP level was high in 73.7% of the cases, and LDH was high in 47.7%. The metastatic lesion was predominantly seen in the bone with red pulp such as lumbar and thoracic vertebra and rib. The median survival time was 189 days (range: 24-509) with a poor prognosis. However, newly developed anticancer drugs were very effective for some cases, indicating that such chemotherapy should be tried for cases with bone metastasis.
authors.affiliation: 3rd Dept. of Surgery, Tokyo Medical University.
authors.forename: Hideo
authors.initials: H
authors.lastname: Sudo
authors.forename: Yu
authors.initials: Y
authors.lastname: Takagi
authors.forename: So
authors.initials: S
authors.lastname: Katayanagi
authors.forename: Sumito
authors.initials: S
authors.lastname: Hoshino
authors.forename: Takeshi
authors.initials: T
authors.lastname: Suda
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hibi
authors.forename: Kazushige
authors.initials: K
authors.lastname: Ito
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tsutida
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Aoki
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000556:secondary*; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate