title: Successful joint arthroplasty after treatment of destructive MRSA arthritis of the knee using antibiotic-loaded hydroxyapatite blocks: a case report.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) septic arthritis is frequently associated with a poor clinical outcome. Joint reconstruction may be worth attempting in patients with a history of persistent MRSA infection. Here we report an unusual case of MRSA septic arthritis of the knee joint that was treated successfully by joint replacement after initial placement of antibiotic-loaded hydroxyapatite (HA) blocks.
authors.affiliation: Department of Orthopedic Surgery, Gifu University School of Medicine, 1-1 Yanagido, Gifu, Gifu City 501-1194, Japan. mkazuu@cc.gifu-u.ac.jp
authors.forename: Kazu
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Mansho
authors.initials: M
authors.lastname: Itokazu
authors.forename: Shuichi
authors.initials: S
authors.lastname: Uemura
authors.forename: Iori
authors.initials: I
authors.lastname: Takigami
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Naganawa
authors.forename: Katsuji
authors.initials: K
authors.lastname: Shimizu
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D001672:Biocompatible Materials / Q000627:therapeutic use*; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery; D016106:Methicillin Resistance; D011859:Radiography; D013203:Staphylococcal Infections / Q000188:drug therapy*; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D014640:Vancomycin; D017886:Durapatite