title: Auditory brainstem implants: surgical aspects.
abstract: Patients with neurofibromatosis type 2 often develop bilateral life-threatening vestibular schwannoma necessitating tumor removal, which results in deafness. We developed the auditory brainstem implant (ABI) in order to be able to electrically stimulate the cochlear nucleus complex in patients with bilateral cochlear nerve injury from bilateral schwannoma. After tumor removal, the electrode array of the ABI is inserted into the lateral recess of the fourth ventricle and placed over the surface of the ventral and dorsal cochlear nuclei. The ABI is designed to stimulate auditory neural structures within the cochlear nucleus in order to convey salient cues about the frequency, amplitude, and temporal characteristics of sounds. To date, more than 200 patients have received an ABI device at our institution. Recently, penetrating ABIs were introduced, and preliminary results of penetrating ABIs are discussed in this paper. The surgical anatomy of the nucleus and surgical placement of the ABI in patients with neurofibromatosis type 2 are described, and surgical considerations in this group of challenging patients are detailed.
authors.affiliation: House Clinic, Los Angeles, Calif., USA.
authors.forename: Jose N
authors.initials: JN
authors.lastname: Fayad
authors.forename: Steven R
authors.initials: SR
authors.lastname: Otto
authors.forename: Derald E
authors.initials: DE
authors.lastname: Brackmann
mesh_terms: D038262:Auditory Brain Stem Implants; D017626:Cochlear Nucleus / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery*; D007758:Ear, Inner / Q000601:surgery; D034381:Hearing Loss / Q000209:etiology / Q000601:surgery*; D006801:Humans; D016518:Neurofibromatosis 2 / Q000150:complications / Q000503:physiopathology; D009464:Neuroma, Acoustic / Q000150:complications / Q000209:etiology; D018579:Patient Selection; D019736:Prostheses and Implants; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome