Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics.
Hinzen
Berthold
B
Department of Chemistry and Antiinfectives and Natural Products, Bayer HealthCare AG Pharmaceutical Research, AiCuris GmbH & Co. KG, Aprather Weg, 42096 Wuppertal, Germany.
Raddatz
Siegfried
S
Paulsen
Holger
H
Lampe
Thomas
T
Schumacher
Andreas
A
Häbich
Dieter
D
Hellwig
Veronica
V
Benet-Buchholz
Jordi
J
Endermann
Rainer
R
Labischinski
Harald
H
Brötz-Oesterhelt
Heike
H
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000648:ultrastructure; D002626:Chemistry, Pharmaceutical; D018360:Crystallography, X-Ray; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D047630:Depsipeptides
D000900:Anti-Bacterial Agents; D010456:Peptides, Cyclic; C585143:acyldepsipeptides; D047630:Depsipeptides