[Pronostic value of the immunohistochemical expression of cyclin D1 (DCS6) in epidermoid larynx carcinoma].
In this paper we carried out an immunohistochemical study of cyclin D1 (DCS6 ) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain) for a time of 5 years. In the cases with lymph node metastasis we also studied cyclin D1 expression at this level. Furthermore we have analysed the value of cyclin D1 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between cyclin D1 expression and other clinic and pathologic parameters.
García Lozano
M C
MC
Servicio ORL, Hospital "Gutiérrez Ortega", Valdepeñas, Ciudad Real. cjangela@castillalmancha.es
Orradre Romero
J L
JL
Sánchez Carrión
S
S
Caro Garcia
M
M
Lasso Luis
O
O
Piris Pinilla
M A
MA
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism*; D019938:Cyclin D1 / Q000096:biosynthesis*; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000378:metabolism*; D011379:Prognosis
D019938:Cyclin D1