Palladium(0)-catalyzed highly regio- and stereoselective addition of organoboronic acids with 1,2-allenylphosphonates forming tri- or tetrasubstituted 1(E)-alkenylphosphonates.
A highly regio- and stereoselective palladium(0)-catalyzed addition of organoboronic acids with 1,2-allenylphosphonates in the presence of HOAc forming tri- or tetrasubstituted 1(E)-alkenylphosphonates is reported in this paper. The stereoselectivity is much higher than the reported cases. The effects of different R(1), R(2), and R(3) were studied. A mechanism of this reaction is proposed on the basis of our previous study.
Ma
Shengming
S
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China. masm@mail.sioc.ac.cn
Guo
Hao
H
Yu
Fei
F