title: Pathophysiology, diagnosis, and management of urinary tract infection in horses.
abstract: Equine urinary tract infection (UTI) most commonly occurs as a sequela to structural or functional inhibition of normal urine flow. Although it is an infrequent diagnosis in equids, the incidence of UTI in human beings is high and has inspired great investigative effort. The resultant findings with potentially broad application as well as current equine studies are reviewed here. Recent developments in the understanding of host-agent interactions and renal defense mechanisms, emerging antimicrobial resistance, and novel therapeutic alternatives to prophylactic antibiotic use are emphasized.
authors.affiliation: Department of Clinical Sciences, Colorado State University Veterinary Medical Center, 300 West Drake, Fort Collins, CO 80526, USA. melinda.frye@colostate.edu
authors.forename: Melinda A
authors.initials: MA
authors.lastname: Frye
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001428:Bacterial Vaccines / Q000627:therapeutic use; D019468:Disease Management; D006734:Horse Diseases / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D006736:Horses; D006801:Humans; D007778:Lactobacillus / Q000502:physiology; D009393:Nephritis / Q000382:microbiology / Q000628:therapy / Q000662:veterinary; D014546:Urinary Catheterization / Q000009:adverse effects / Q000662:veterinary; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy / Q000662:veterinary*; D029799:Vaccinium macrocarpon / Q000502:physiology
chemical_list: D000890:Anti-Infective Agents; D001428:Bacterial Vaccines