ZnO as a new catalyst for N-formylation of amines under solvent-free conditions.
The treatment of amines with formic acid in the presence of ZnO under solvent-free conditions brings about highly and efficient N-formylation to give the corresponding formamides in excellent yields. The N-formylation reaction not only involves mild conditions, simple operation, and high yields but also high chemoselectivity.
Hosseini-Sarvari
Mona
M
Department of Chemistry, Faculty of Science, Shiraz University, Shiraz 71454, I.R., Iran. hossaini@susc.ac.ir
Sharghi
Hashem
H
D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D012997:Solvents; D015034:Zinc Oxide / Q000737:chemistry*
D000588:Amines; D000814:Aniline Compounds; D012997:Solvents; C023650:aniline; D015034:Zinc Oxide