[Diagnosis and treatment of patients with cholangiocarcinoma].
OBJECTIVE
To explore the diagnosis and treatment of the cholangiocarcinoma.


METHODS
Forty one patients with cholangiocarcinoma who were enrolled in our hospital from January 1970 to January 2005 were retrospectively analyzed.


RESULTS
Among these 41 patients, the 1, 3, and 5-year survival rate was 82.3%, 45.8%, 45.8%, respectively, with radical operation, and was 11.0%, 0, 0 with non-radical operation (chi2 = 21.38, P < 0.01). The 1-year and 3-year survival rate was 11.0% and 0 in 9 patients treated with laparatomy, which was not significantly different from those treated with non-radical operation (chi2 = 0.02, P = 0.89). Four patients did not receive operation and all died within one year. Among 25 patients who did not experience lymph node metastasis, the 1, 3, and 5-year survival rate was 58.4%, 27.3%, and 27.3%. Among 16 patients who were found lymph node metastasis, the 1-year and 3-year survival rate was 61.8% and 0 (chi2 = 13.85, P < 0.01).


CONCLUSIONS
Operation is the most effective treatment for cholangiocarcinoma. Radical operation is the only curative treatment.
Wu
Jian-Xiong
JX
Department of General Surgical Oncology, Cancer Hospital, CAMS and PUMC, Beijing 100021, China. dr_wujianxiong@yahoo.com.cn
Hu
Shi-Jie
SJ
Rong
Wei-Qi
WQ
Wang
Li-Ming
LM
Shao
Yong-Fu
YF
D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male