Effect of heavy ion irradiation on DNA DSB repair in Methanosarcina barkeri.
Archaea are expected to be highly repair proficient since they survived the vicious onslaught of radiation damage at the time of their early appearance. The DNA double strand break repairing ability of mesophilic archaea Methanosarcina barkeri (DSM 804) was studied using (7)Li, (12)C and (16)O heavy ions and compared with that of (60)Co gamma-rays. They can repair double strand breaks and, as in eukaryotes, the nature as well as extent of induction and its subsequent repair were dependent on the linear energy transfer of the radiation source.
Raychaudhuri
Shaon
S
Jadavpur University, Raja SC Mullick Road, Calcutta 700032, India.
Karmakar
Parimal
P
Choudhary
Dharamainder
D
Sarma
Asiti
A
Thakur
Ashoke Ranjan
AR