title: Tandem Diels-Alder cycloadditions of 2-pyrone-5-acrylates for the efficient synthesis of novel tetracyclolactones.
abstract: Readily prepared from the regioselective Pd-catalyzed coupling reactions of 3,5-dibromo-2-pyrone, 3-bromo-2-pyrone-5-carboxylates undergo tandem uninterrupted sequential Diels-Alder cycloaddition reactions with allyl vinyl ethers in a highly regio- and stereoselective fashion to provide a series of novel tetracyclolactones in good yields.
authors.affiliation: Department of Chemistry, Hanyang University, Seoul 131-791, Korea.
authors.forename: Soo-Im
authors.initials: SI
authors.lastname: Chung
authors.forename: Joobeom
authors.initials: J
authors.lastname: Seo
authors.forename: Cheon-Gyu
authors.initials: CG
authors.lastname: Cho