Myelodysplastic syndrome transformed into Acute Lymphoblastic Leukaemia (FAB:L3).
Myelodysplastic syndrome (MDS) is recognized as a preleukaemic disorder with a variable risk of transformation to acute myeloid leukaemia. Usually the blast cells in leukaemia are transformed after MDS displays a myeloid phenotype. Even though lymphoid progression had been reported previously, most displayed myeloid-lymphoid hybrid or early B phenotype. We report a case of an elderly man who had MDS transformed into Acute Lymphoblastic Leukaemia (ALL:L3) which is a rare lymphoid transformation.
Zainina
S
S
Department of Clinical Laboratory Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia. zainina@medic.upm.edu.my
Cheong
S K
SK
D000753:Anemia, Refractory / Q000473:pathology*; D001854:Bone Marrow Cells / Q000473:pathology; D002051:Burkitt Lymphoma / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged