Presence of PACAP and VIP in embryonic chicken brain.
The aim of the present article was to investigate the occurrence and temporary changes of pituitary adenylate cyclase-activating polypeptide (PACAP)-38 and vasoactive intestinal peptide (VIP) in various brain areas of chicken embryos by means of radioimmunoassay. The highest concentrations of PACAP-38 were measured in the brain stem followed by the hypothalamus, cerebellum, and telencephalon. PACAP-38 levels were significantly higher than those of VIP in all examined brain areas. The levels of both PACAP-38 and VIP showed a tendency to decrease until hatching during embryonic development of the chicken.
Jozsa
Rita
R
Department of Anatomy, University of Pécs, 7624 Pécs, Szigeti u 12. Hungary. rita.jozsa@aok.pte.hu
Hollosy
Tibor
T
Nemeth
Jozsef
J
Tamás
Andrea
A
Lubics
Andrea
A
Jakab
Balazs
B
Olah
Andras
A
Arimura
Akira
A
Reglödi
Dora
D
D000818:Animals; D001921:Brain / Q000196:embryology* / Q000378:metabolism*; D002642:Chick Embryo; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide / Q000378:metabolism*; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
D051219:Pituitary Adenylate Cyclase-Activating Polypeptide; D014660:Vasoactive Intestinal Peptide