Diphenylphosphinoyl chloride as a chlorinating agent--the selective double activation of 1,2-diols.
Treatment of 1,2-diols with diphenylphosphinoyl chloride in pyridine produces beta-chloroethyl phosphinates which react with complete control of stereochemistry to give epoxides and azido-alcohols, useful intermediates in cyclopropane synthesis.
Fox
David J
DJ
University Chemical Laboratory, Lensfield Road, Cambridge, UK. djf34@cam.ac.uk
Pedersen
Daniel Sejer
DS
Petersen
Asger B
AB
Warren
Stuart
S