title: Fixed exanthema from systemic tobramycin.
abstract: Eye drops contain several ophthalmic medications which can produce allergic reactions. We report the case of a patient with contact dermatitis from neomycin and a probable fixed exanthema after parenteral administration of tobramycin who tolerated topical tobramycin and other aminoglycosides.
authors.affiliation: Allergy Department, Hospital Clínico San Carlos, Madrid, Spain. igrubio@hotmail.com
authors.forename: I
authors.initials: I
authors.lastname: García-Rubio
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Cócera
authors.forename: T
authors.initials: T
authors.lastname: Robledo Echarren
authors.forename: S
authors.initials: S
authors.lastname: Vázquez Cortés
mesh_terms: D000368:Aged; D000617:Aminoglycosides / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D003429:Cross Reactions; D004342:Drug Hypersensitivity / Q000209:etiology / Q000276:immunology; D005076:Exanthema / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007159:Immunologic Tests; D009355:Neomycin / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D009883:Ophthalmic Solutions; D012882:Skin Tests; D014031:Tobramycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions; D009355:Neomycin; D014031:Tobramycin