[Precocious puberty].
Precocious puberty is usually defined as the appearance of secondary sexual development before the age of 8 years in girls and 9 years in boys. Precocious puberty is a heterogenous condition generally divided into central and peripheral forms driven respectively by hypothalamic-pituitary axis or by excessive production of sex steroids. Taking into account the risk associated with the underlying disorder as well as the impact of precocious puberty on stature growth and development of reproductive and mental functions, this condition has important consequences for affected children and their families. In this paper, the pathophysiology, clinical presentation, laboratory and radiological features, and treatment of the disorders leading to precocious puberty are reviewed. Particular attention is devoted to the results of the recently published studies.
Krysiak
Robert
R
Slaska Akademia Medyczna w Katowicach, Katedra Farmakologii, Zakład Farmakologii Klinicznej. r.krysiak@pharmanet.com.pl
Okopień
Bogusław
B
Herman
Zbigniew Stanisław
ZS
D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011629:Puberty, Precocious / Q000175:diagnosis* / Q000628:therapy*