title: [Clinical study on effects of tiepi fengdou granule/capsule combined with chemotherapy and/or radiotherapy in treating lung cancer with Qi-Yin asthenia syndrome].
abstract: OBJECTIVE
  To study the clinical efficaly and safety of Tiepi Fengdou Granule (TFG) and Capsule (TFC) combined with chemotherapy and/or radiotherapy in treating lung cancer patients with Qi-Yin asthenia syndrome (QYAS).
  
  
  METHODS
  Eighty patients were randomly assigned into 3 groups: the TFG group (32 cases), the TFC group (32 cases) and the Shengmai Capsule control group (16 cases). Changes of symptoms of QYAS, main symptoms of lung cancer, Karnofsky scoring as well as the blood routine test were observed.
  
  
  RESULTS
  The total effective rate of symptom improving in the TFG group and the TFC group was 81.2% and 93.3% respectively, showing insignificant difference between the 2 groups (P > 0.05), but both were higher than that in the Shengmai Capsule control group (50.0%, P < 0.05 and P < 0.01). Additionally, as compared with those before treatment, the neutrophil count increased and the lymphocytes count obviously decreased in the TFC group after treatment (all P < 0.05).
  
  
  CONCLUSIONS
  Both dose-forms of the remedies, TFC and TFG, have significant effects in treating lung cancer with QYAS, but with insignificant difference between them.
authors.affiliation: Zhejiang Cancer Hospital, Hangzhou. springcxp@yahoo.com.cn
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Chen
authors.forename: Yi-ping
authors.initials: YP
authors.lastname: Zhang
authors.forename: Xian-ru
authors.initials: XR
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage; D005260:Female; D006801:Humans; D017567:Karnofsky Performance Status; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D019413:Qi; D016710:Yin Deficiency / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal