Characteristic length scale of electric transport properties of genomes.
A tight-binding model together with a statistical method are used to investigate the relation between the sequence-dependent electric transport properties and the sequences of protein-coding regions of complete genomes. A correlation parameter Omega is defined to analyze the relation. For some particular propagation length w max, the transport behaviors of the coding and noncoding sequences are very different and the correlation reaches its maximal value Omega max. w max and Omega max are characteristic values for each species. A possible reason for the difference between the features of transport properties in the coding and noncoding regions is the mechanism of DNA damage repair processes together with natural selection.
Shih
C T
CT
Department of Physics, Tunghai University, Taichung, Taiwan.
D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D004249:DNA Damage; D004260:DNA Repair; D004563:Electrochemistry / Q000379:methods*; D004579:Electron Transport; D016681:Genome, Fungal; D008956:Models, Chemical; D008958:Models, Molecular; D016366:Open Reading Frames; D017422:Sequence Analysis, DNA / Q000379:methods*
D004247:DNA