title: Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination.
authors.affiliation: The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
authors.forename: Alexander G
authors.initials: AG
authors.lastname: Maier
authors.forename: Joanna A M
authors.initials: JA
authors.lastname: Braks
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Waters
authors.forename: Alan F
authors.initials: AF
authors.lastname: Cowman
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology; D043525:Cytosine Deaminase / Q000235:genetics*; D005437:Flucytosine / Q000494:pharmacology; D017353:Gene Deletion; D018390:Gene Targeting; D006801:Humans; D010430:Pentosyltransferases / Q000235:genetics*; D010963:Plasmodium falciparum / Q000187:drug effects / Q000235:genetics*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D012641:Selection, Genetic; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics; D014162:Transfection; D014227:Triazines / Q000494:pharmacology
chemical_list: D000962:Antimalarials; D011993:Recombinant Fusion Proteins; D014227:Triazines; C006201:BRL 6231; D005437:Flucytosine; D013762:Tetrahydrofolate Dehydrogenase; D010430:Pentosyltransferases; C023269:uracil phosphoribosyltransferase; D043525:Cytosine Deaminase