Insertion-deletion polymorphism in the angiotensin-converting enzyme (ACE) gene among Sudanese, Somalis, Emiratis, and Omanis.
The angiotensin-converting enzyme (ACE) gene in humans contains an insertion-deletion polymorphism in its intron 16. Because of its involvement with the renin-angiotensin system, the insertion-deletion polymorphism of the ACE gene has been widely investigated in different populations and in case-control studies. However, similar studies for Arab populations are limited in number. Therefore we have investigated the frequencies of the *I and *D alleles of the ACE gene among Sudanese, Somalis, and Arab nationals of the United Arab Emirates and Oman using previously described methods. Our data indicate a preponderance of the *D allele among the Arab and African populations studied (Sudanese, 0.64; Somalis, 0.73; Emiratis, 0.61; and Omanis, 0.71).
Bayoumi
Riad A
RA
Department of Biochemistry, Medicine and Physiology, College of Medicine, Sultan Qaboos University, Sultanate of Oman.
Simsek
M
M
Yahya
Taher M
TM
Bendict
Sheela
S
Al-Hinai
Ali
A
Al-Barwani
Hameeda
H
Hassan
M O
MO
D000351:Africa, Eastern; D000483:Alleles; D005828:Genetics, Population / Q000379:methods*; D006801:Humans; D008877:Middle East; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
D007703:Peptidyl-Dipeptidase A