Clinical inquiries. Which vaccinations are indicated after splenectomy?
Immunization against encapsulated bacterial pathogens decreases the incidence of post-splenectomy sepsis. Pneumococcal, meningococcal, and Haemophilus influenzae (Hib) vaccinations are indicated for patients after splenectomy. These immunizations should be given at least 14 days before a scheduled splenectomy, or given after the fourteenth postoperative day (strength of recommendation [SOR]: A, based on systematic review of RCTs for the pneumococcal vaccine; SOR: B, based on systematic review of clinical trials for meningococcal and Hib vaccines).
Webb
Charles W
CW
University of North Carolina, Chapel Hill, NC, USA.
Crowell
Karen
K
Cravens
David
D
D001424:Bacterial Infections / Q000276:immunology / Q000517:prevention & control*; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D019317:Evidence-Based Medicine; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D013156:Splenectomy / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000276:immunology / Q000517:prevention & control*; D013997:Time Factors
D001428:Bacterial Vaccines