title: Meta-analysis of the efficacy and safety of intradiscal electrothermal therapy (IDET).
abstract: OBJECTIVE
  The objective of this study was to determine the representative outcomes of the intradiscal electrothermal therapy (IDET) procedure in terms of pain relief, reduction of disability, and risk of complications.
  
  
  METHODS
  Meta-analysis, using a random-effects model. A Medline literature search was conducted using search terms associated with the IDET procedure including IDET, intradiscal electrothermal therapy, intervertebral disk, and annuloplasty.
  
  
  METHODS
  The outcomes analyzed were the visual analog scale (VAS) assessment of pain, the bodily pain, and physical functioning subscales of the SF-36 health survey, and the Oswestry disability index.
  
  
  RESULTS
  From 1998 to March 2005, 62 peer-reviewed articles were identified regarding the IDET procedure. Forty-five articles were excluded, leaving a total of 17 unique published reports included in this review. The overall mean improvement in pain intensity was 2.9 points as measured by the VAS. The overall mean improvement in physical function was 21.1 points as measured by the SF-36. The overall mean improvement in bodily pain was 18.0 points as measured by the SF-36. The overall mean improvement in disability was 7.0 points as measured by the Oswestry disability index. The overall incidence of complications was 0.8%.
  
  
  CONCLUSIONS
  Although variation exists in the reported outcomes among the various studies of the IDET procedure, the pooled results of the published studies provide compelling evidence of the relative efficacy and safety of the IDET procedure.
authors.affiliation: Smith & Nephew, Endoscopy, Biostatistics, Andover, Massachusetts, USA. david.appleby@smith-nephew.com
authors.forename: David
authors.initials: D
authors.lastname: Appleby
authors.forename: Gunnar
authors.initials: G
authors.lastname: Andersson
authors.forename: Michael
authors.initials: M
authors.lastname: Totta
mesh_terms: D001416:Back Pain / Q000453:epidemiology* / Q000517:prevention & control*; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D015897:Comorbidity; D004599:Electric Stimulation Therapy / Q000706:statistics & numerical data*; D006801:Humans; D006979:Hyperthermia, Induced / Q000706:statistics & numerical data*; D007405:Intervertebral Disc Displacement / Q000453:epidemiology* / Q000628:therapy*; D016016:Proportional Hazards Models; D020127:Recovery of Function; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016896:Treatment Outcome