title: [Serious course of sepsis in diabetic patients].
abstract: The aim of the study was to evaluate the frequency and the course of sepsis in the patients treated in our ward. Retrospective evaluation was conducted on a group of 7418 patients hospitalized in 2001-2005. Serious sepsis was found in 15 patients (0.2%). Analysis was conducted on two groups of patients: diabetic (group A) and non-diabetic (group B). The majority of patients had community-acquired infection (93.3%). Critical course of sepsis was observed in 53.3% of patients. Mortality was higher in group A (83.3%) compared to B (33.3%). In group A other, pre-existing diseases were more frequent. The most frequent focus of infection was urinary tract, followed by respiratory system. In group A the focus of infection was in 33.3% each urinary tract, respiratory tract and diabetic foot. Only in 66.7% of patients pathogens were cultured from body fluid. Multiple pathogens were more frequent in group B. Co-existing fungal infections were more frequent in group A (16.6%) than in B (11.1%). The empirical therapy was ineffective in 75% of diabetic and 50% of non-diabetic patients.
  
  
  CONCLUSIONS
  1) In severe sepsis mortality is high, and in diabetic patients it amounts to 80%. 2) In > 30% patients bacteriological tests did not confirm the type of pathogen. 3) In diabetic patients fungal infections were more frequent. 4) Critical course of sepsis may result from co-existing morbidity.
authors.affiliation: I Oddział Chorób Wewnetrznych, Endokrynologii i Diabetologii, SPZOZ Wojewódzki Szpital Zespolony im. J. Sniadeckiego w Białymstoku.
authors.forename: Iwona
authors.initials: I
authors.lastname: Jakubowska
authors.forename: Dorota
authors.initials: D
authors.lastname: Lukasiewicz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D048909:Diabetes Complications / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records / Q000706:statistics & numerical data; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D018805:Sepsis / Q000453:epidemiology*; D012720:Severity of Illness Index