A chiral primary amine thiourea catalyst for the highly enantioselective direct conjugate addition of alpha,alpha-disubstituted aldehydes to nitroalkenes.
Lalonde
Mathieu P
MP
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Chen
Yonggang
Y
Jacobsen
Eric N
EN
D000447:Aldehydes / Q000737:chemistry* / Q000378:metabolism; D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D008956:Models, Chemical; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
D000447:Aldehydes; D000475:Alkenes; D000588:Amines; D009574:Nitro Compounds; D013890:Thiourea