title: Multiresidue analysis of avermectins in cattle liver by liquid chromatography/tandem mass spectrometry.
abstract: A simple multiresidue analysis method was developed for the confirmation and quantification of eprinomectin, abamectin, doramectin, and ivermectin in cattle liver. The target analytes were extracted with acetonitrile and cleaned up with C18 and C8 solid-phase extraction cartridges before analysis by liquid chromatography combined with positive ion electrospray tandem mass spectrometry. The residue mean recoveries of the 4 drugs were 64.16-99.53%. The limit of detection was 2.5 ng/g for eprinomectin, abamectin, doramectin, and ivermectin.
authors.affiliation: China Agricultural University, College of Veterinary Medicine, Department of Pharmacology and Toxicology, Beijing 100094, People's Republic of China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Hou
authors.forename: Haiyang
authors.initials: H
authors.lastname: Jiang
authors.forename: Shuangyang
authors.initials: S
authors.lastname: Ding
authors.forename: Suxia
authors.initials: S
authors.lastname: Zhang
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Li
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Shen
mesh_terms: D000818:Animals; D002417:Cattle; D002623:Chemistry Techniques, Analytical / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods*; D007306:Insecticides / Q000032:analysis; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000032:analysis; D008099:Liver / Q000378:metabolism*; D013058:Mass Spectrometry / Q000379:methods*; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
chemical_list: D007306:Insecticides; C048324:abamectin; D007559:Ivermectin; C019264:avermectin; C101434:eprinomectin; C084101:doramectin