title: Rapid long-distance hole transfer through consecutive adenine sequence.
abstract: Long-distance hole transfer via A-hopping over a long A sequence in DNA has been studied by time-resolved transient absorption measurements. DNA modified with naphthalimide (NI) and phenothiazine (PTZ), in which two molecules are separated by a consecutive A sequence, was synthesized to investigate the hole transfer process via A-hopping. After the laser-pulse excitation of NI, an NI radical anion and PTZ radical cation were produced within the laser pulse duration (8 ns) even in the case of an A30 sequence. Hole transfer efficiency from A adjacent to NI to PTZ was weakly distance dependent, showing that the hole transfer process through a consecutive A sequence proceeds via a multistep mechanism. These results clearly suggest that the hole transfer via A-hopping in DNA takes place efficiently and rapidly.
authors.affiliation: The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Mihogaoka 8-1, Ibaraki, Osaka, Japan.
authors.forename: Tadao
authors.initials: T
authors.lastname: Takada
authors.forename: Kiyohiko
authors.initials: K
authors.lastname: Kawai
authors.forename: Mamoru
authors.initials: M
authors.lastname: Fujitsuka
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Majima
mesh_terms: D000225:Adenine / Q000737:chemistry*; D001483:Base Sequence; D004247:DNA / Q000737:chemistry
chemical_list: D004247:DNA; D000225:Adenine