title: A new diphenyl ether from marine-derived fungus Aspergillus sp. B-F-2.
abstract: A new diphenyl ether dimethyl 2,3'-dimethylosoate (1) together with three known compounds monomethylsulochrin (2), emodin (3), and questin (4) were isolated through bioassay-guided fractionations from the culture of a marine-derived fungus Aspergillus sp. B-F-2. The structures of these compounds were determined by spectroscopic methods. Cytotoxicities of compounds 1 and 2 against K562 cell line were preliminarily evaluated by the MTT method and flow cytometry.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, Qingdao.
authors.forename: Rui
authors.initials: R
authors.lastname: Liu
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
authors.forename: Yapeng
authors.initials: Y
authors.lastname: Zhang
authors.forename: Tianjiao
authors.initials: T
authors.lastname: Zhu
authors.forename: Hongbing
authors.initials: H
authors.lastname: Liu
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Fang
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D001230:Aspergillus / Q000378:metabolism*; D006801:Humans; D020014:K562 Cells; D010647:Phenyl Ethers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014871:Water Microbiology
chemical_list: D000903:Antibiotics, Antineoplastic; D010647:Phenyl Ethers; C031538:phenyl ether