title: Ciguatera: Australian perspectives on a global problem.
abstract: Ciguatera is a global disease caused by the consumption of certain warm-water fish that have accumulated orally effective levels of sodium channel activator toxins (ciguatoxins) through the marine food chain. Symptoms of ciguatera arising from the consumption of ciguateric fish include a range of gastrointestinal, neurological and cardiovascular disturbances. This review examines progress in our understanding of ciguatera from an Australian perspective, especially the laboratory-based research into the problem that was initiated by the late "Bob" Endean at the University of Queensland.
authors.affiliation: Institute for Molecular Biosciences, The University of Queensland, Qld. 4072, Australia. r.lewis@imb.uq.edu.au
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Lewis
mesh_terms: D000818:Animals; D001315:Australia; D036841:Ciguatera Poisoning / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D002922:Ciguatoxins / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology; D003937:Diagnosis, Differential; D004141:Dinoflagellida; D006801:Humans; D015222:Sodium Channels / Q000187:drug effects
chemical_list: D015222:Sodium Channels; D002922:Ciguatoxins