title: Lanostane triterpenoids from the Sri Lankan basidiomycete Ganoderma applanatum.
abstract: Two new lanostane-type triterpenoids, 3alpha,16alpha-dihydroxylanosta-7,9(11),24-trien-21-oic acid (1) and 3alpha,16alpha,26-trihydroxylanosta-7,9(11),24-trien-21-oic acid (2), along with three known lanostanoids, 16alpha-hydroxy-3-oxolanosta-7,9(11),24-trien-21-oic acid (3), 3alpha-carboxyacetoxy-24-methylen-23-oxolanost-8-en-26-oic acid (4), and 3alpha-carboxyacetoxy-24-methyl-23-oxolanost-8-en-26-oic acid (5), have been isolated from the EtOAc extract of the fruiting body of Ganoderma applanatum. The structures of 1, 2, and 3 were determined directly by the interpretation of spectroscopic data, while the structures of 4 and 5 were assigned by comparison of spectroscopic data against literature values.
authors.affiliation: Department of Chemistry, University of Colombo, P.O. Box 1490, Colombo 3, Sri Lanka. dilip.desilva@canterbury.ac.nz
authors.forename: E Dilip
authors.initials: ED
authors.lastname: de Silva
authors.forename: Sonia A
authors.initials: SA
authors.lastname: van der Sar
authors.forename: R G Lalith
authors.initials: RG
authors.lastname: Santha
authors.forename: Ravi L C
authors.initials: RL
authors.lastname: Wijesundera
authors.forename: Anthony L J
authors.initials: AL
authors.lastname: Cole
authors.forename: John W
authors.initials: JW
authors.lastname: Blunt
authors.forename: Murray H G
authors.initials: MH
authors.lastname: Munro
mesh_terms: D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D032902:Ganoderma / Q000737:chemistry*; D007810:Lanosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D013188:Sri Lanka; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D014315:Triterpenes; D007810:Lanosterol