title: [Integral estimate of endogenous intoxication and its correction with sodium hypochlorite in inflammatory diseases of small pelvic organs].
abstract: The parameters of endogenous intoxication (EI) were studied in patients with inflammatory small pelvic organs diseases complicated by organs pelviperitonitis and generalized peritonitis. The integral index of EI--endogenous intoxication coefficient (EIC) was developed, which included relative values (as to the normal values) of the total and effective concentration of albumin, medium molecular peptides and leukocytic intoxication index. The values multiplied together are EIC. In patients with inflammatory small pelvic organs diseases, the level of EI was shown to considerably increase. The use of EIC was ascertained to significantly increase the accuracy of diagnosis of early-stage EI, to perform detoxifying therapy, and monitor its efficiency, as confirmed by the use of sodium hypochlorite in the combined treatment of patients with inflammatory small pelvic organs diseases.
authors.forename: S B
authors.initials: SB
authors.lastname: Matveev
authors.forename: N I
authors.initials: NI
authors.lastname: Tikhomirova
authors.forename: O B
authors.initials: OB
authors.lastname: Shakhova
authors.forename: E V
authors.initials: EV
authors.lastname: Klychnikova
authors.forename: B V
authors.initials: BV
authors.lastname: Davydov
mesh_terms: D005260:Female; D006801:Humans; D007958:Leukocyte Count / Q000379:methods; D008297:Male; D008991:Monitoring, Physiologic; D016877:Oxidants / Q000494:pharmacology*; D000292:Pelvic Inflammatory Disease / Q000097:blood / Q000473:pathology / Q000628:therapy*; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D016060:Sorption Detoxification / Q000379:methods
chemical_list: D016877:Oxidants; D012973:Sodium Hypochlorite