title: Suxamethonium-induced hyperkalaemia in a patient with a normal potassium level before rapid-sequence intubation.
abstract: The use of suxamethonium (succinylcholine) for rapid-sequence intubation may be limited by hyperkalaemia. Modest pre-induction hyperkalaemia is usually disregarded. We present a patient who underwent emergency surgery for a perforated peptic ulcer after being bedbound for 26 days because of a head injury. Serum potassium level was 4.0 mmol/L. The patient was intubated after injection of sedative and suxamethonium and, about 3 minutes later, developed ventricular arrhythmia. Blood tests during resuscitation showed a serum potassium level of 8.8 mmol/L. Immobilisation, denervation and intra-abdominal infection were risk factors for hyperkalaemia in this patient. This report reinforces the need to identify risk factors for hyperkalaemia before administration of suxamethonium, even when serum potassium levels are normal.
authors.affiliation: Department of Anesthesiology, National Cheng Kung University Medical College, Tainan, Taiwan.
authors.forename: Yu-Li
authors.initials: YL
authors.lastname: Pang
authors.forename: Fan-Ling
authors.initials: FL
authors.lastname: Tseng
authors.forename: Yu-Chuan
authors.initials: YC
authors.lastname: Tsai
authors.forename: Yen-Chin
authors.initials: YC
authors.lastname: Liu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006429:Hemiplegia / Q000150:complications; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced*; D020198:Intracranial Hemorrhage, Traumatic / Q000150:complications; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D008297:Male; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects*; D010439:Peptic Ulcer Perforation / Q000150:complications / Q000601:surgery; D012307:Risk Factors; D013390:Succinylcholine / Q000009:adverse effects*
chemical_list: D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine