title: [Nutritional condition in patients with Alzheimer-type dementia from the neurosciences' group, Medellín 2004].
abstract: BACKGROUND
  Patients suffering clinical dementia caused by Alzheimer's disease have a high risk of developing malnutrition caused by all the physiological, socio-economic and psychological changes related to the disease, together with the ageing process.
  
  
  OBJECTIVE
  To describe the nutritional condition of a group of patients with Alzheimer's dementia according to the degree of disease severity. Patients were selected from the University of Antioquia Neurosciences Group.
  
  
  METHODS
  Descriptive cross sectional study. Patients were assessed and information was collected about their body composition, food consumption behaviour, clinical, and psychosocial variables.
  
  
  RESULTS
  77 patients were studied; their mean age was 65, 5 +/- 12.8 years. 48 had a family history of Alzheimer's disease; 39 were diagnosed more than 60 months before the study started; the most frequently found degree of severity was moderate, the most common type of dementia was the early family form. 26 began the disease process before they were 50 years old. Significant differences for Body Mass Index, brachial adipose area and brachial lean area were found (p = 0.001, p = 0.000, p = 0.000, respectively) between patients with the different degrees of disease severity. These parameters measures were lowest in patients with severe disease. The intake of calcium and folate was the lowest amongst the nutrients studied.
  
  
  CONCLUSIONS
  The nutritional state is impaired in patients suffering Alzheimer's dementia from the early stages of the disease. The most important nutritional and clinical abnormalities found were depletion of the lean and fat stores, low intake of calcium and folate and clinical signs of the disease. Changes in these parameters worsen as the disease progresses.
authors.affiliation: Escuela de Nutrición y Dietética, Grupo de Investigación en Alimentación y Nutrición Humana, Universidad de Antioquia, Medellín, Colombia.
authors.forename: Angélica María
authors.initials: AM
authors.lastname: Muñoz
authors.forename: Gloria María
authors.initials: GM
authors.lastname: Agudelo
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Lopera
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology*; D001823:Body Composition; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D004435:Eating; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition; D008875:Middle Aged; D009488:Neurosciences; D015596:Nutrition Assessment; D009752:Nutritional Status; D011795:Surveys and Questionnaires