title: Secondary glaucoma associated with bilateral Aspergillus niger endophthalmitis in an HIV-positive patient: case report.
abstract: Aspergillus endophthalmitis is usually related to systemic or local dissemination in immunosuppressed subjects. The authors report a rare case of severe bilateral glaucoma secondary to an intraocular infection with Aspergillus niger, in the absence of any detectable focus of aspergillosis, in an HIV-infected patient. There were no confirming signs of injection drug use, and the agent was isolated after inoculation in experimental animals. This case shows that Aspergillus endophthalmitis should be considered in non-injecting drug users and HIV-infected patients even in the absence of systemic aspergillosis.
authors.affiliation: Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Av. Bandeirantes, 3900 Ribeirão Preto, SP, Brazil. jayterdepaula@yahoo.com.br
authors.forename: Jayter Silva
authors.initials: JS
authors.lastname: Paula
authors.forename: Agostinho
authors.initials: A
authors.lastname: Bryk
authors.forename: Argemiro
authors.initials: A
authors.lastname: Lauretti Filho
authors.forename: Erasmo
authors.initials: E
authors.lastname: Romão
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis / Q000382:microbiology*; D001234:Aspergillus niger / Q000302:isolation & purification*; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology*; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D012720:Severity of Illness Index