title: Synthesis of 3-fluoroazetidines.
abstract: N-(Alkylidene or 1-arylmethylidene)-2-propenylamines were regiospecifically functionalized to novel N-(alkylidene or 1-arylmethylidene)-3-bromo-2-fluoropropylamines, which were proven to be excellent precursors for 3-fluoroazetidines.
authors.affiliation: Department of Organic Chemistry, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, B-9000 Ghent, Belgium.
authors.forename: Willem
authors.initials: W
authors.lastname: Van Brabandt
authors.forename: Guido
authors.initials: G
authors.lastname: Verniest
authors.forename: Dirk
authors.initials: D
authors.lastname: De Smaele
authors.forename: Guillaume
authors.initials: G
authors.lastname: Duvey
authors.forename: Norbert
authors.initials: N
authors.lastname: De Kimpe
mesh_terms: D001384:Azetidines / Q000138:chemical synthesis* / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D017611:Fluorine Compounds / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001384:Azetidines; D017611:Fluorine Compounds