title: Expedient synthesis of substituted (S)-N-(alpha-methylbenzyl)aziridines.
abstract: We report for the first time that after O-acylation the conjugate addition products of (S)-N-(alpha-methylbenzyl)hydroxylamine undergo an efficient diastereoselective 3-exo-tet ring-closure reaction affording 2- and 2,3-disubstituted-N-alkylaziridines in good to excellent yields.
authors.affiliation: School of Chemical Sciences & Pharmacy, University of East Anglia, Norwich, Norfolk, UK. s.bew@uea.ac.uk
authors.forename: Sean P
authors.initials: SP
authors.lastname: Bew
authors.forename: David L
authors.initials: DL
authors.lastname: Hughes
authors.forename: Vladimir
authors.initials: V
authors.lastname: Savic
authors.forename: Katy M
authors.initials: KM
authors.lastname: Soapi
authors.forename: Martin A
authors.initials: MA
authors.lastname: Wilson