Molecular biology: silencing unlimited.
Heterochromatin domains are essential for normal chromosome functions. The Eri1 ribonuclease is a negative regulator of the RNA interference machinery; recent studies have shown that, in fission yeast lacking Eri1, heterochromatin formation is more promiscuous.
Almeida
Ricardo
R
Wellcome Trust Centre for Cell Biology, 6.34 Swann Building, King's Buildings, University of Edinburgh, Edinburgh EH9 3JR, UK.
Buscaino
Alessia
A
Allshire
Robin C
RC
D005095:Exoribonucleases / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D006570:Heterochromatin / Q000378:metabolism / Q000502:physiology*; D008954:Models, Biological; D034622:RNA Interference; D012568:Schizosaccharomyces
D006570:Heterochromatin; C511955:Eri1 protein, S pombe; D005095:Exoribonucleases