title: Large genomic alterations in hMSH2 and hMLH1 in early-onset colorectal cancer: identification of a large complex de novo hMLH1 alteration.
authors.forename: L
authors.initials: L
authors.lastname: Smith
authors.forename: A
authors.initials: A
authors.lastname: Tesoriero
authors.forename: L
authors.initials: L
authors.lastname: Mead
authors.forename: S
authors.initials: S
authors.lastname: Royce
authors.forename: G
authors.initials: G
authors.lastname: Grubb
authors.forename: J
authors.initials: J
authors.lastname: Young
authors.forename: G
authors.initials: G
authors.lastname: Giles
authors.forename: M
authors.initials: M
authors.lastname: Jenkins
authors.forename: F
authors.initials: F
authors.lastname: Macrae
authors.forename: J L
authors.initials: JL
authors.lastname: Hopper
authors.forename: M C
authors.initials: MC
authors.lastname: Southey
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000328:Adult; D014408:Biomarkers, Tumor / Q000235:genetics*; D002352:Carrier Proteins / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics; D042241:Early Diagnosis; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D008297:Male; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D017384:Sequence Deletion
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D014408:Biomarkers, Tumor; D002352:Carrier Proteins; D005819:Genetic Markers; C501486:MLH1 protein, human; D009687:Nuclear Proteins; C497172:MSH2 protein, human; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein