[Lacrimal film evaluation of patients with facial dystonia during botulinum toxin type A treatment].
OBJECTIVE
To determine the effect of botulinum toxin injection in the eyelid on lacrimal film in patients with facial dystonia.


METHODS
Twenty-four patients with essential blepharospasm and hemifacial spasm were submitted to botulinum toxin injection and lacrimal film tests were performed before the application and after seven and thirty days.


RESULTS
There was improvement in symptoms of dry eye and rose bengal test, however, the breakup time and Schirmer's test did not show significant variation between pretreatment and after 1 month of follow-up.


CONCLUSIONS
The dry eye symptoms in patients with facial dystonia may be attenuated by botulinum toxin due to its possible inhibitory effect on the orbicular muscle leading to a decrease in lacrimal pump.
Costa
Patricia Grativol
PG
Departamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. patriciagrativol@yahoo.com.br
Cardoso
Ivana Pereira
IP
Saraiva
Fabio Petersen
FP
Raiza
Ana Carolina Pasquini
AC
Tanaka
Lílian Keiko
LK
Matayoshi
Suzana
S
D000368:Aged; D000369:Aged, 80 and over; D001764:Blepharospasm / Q000150:complications / Q000188:drug therapy*; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D015352:Dry Eye Syndromes / Q000209:etiology*; D020821:Dystonic Disorders / Q000188:drug therapy; D005260:Female; D019569:Hemifacial Spasm / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D011446:Prospective Studies; D013666:Tears / Q000187:drug effects*; D013997:Time Factors
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A