Effect of anterior capsule polishing on the posterior capsule opacification-inhibiting properties of a sharp-edged, 3-piece, silicone intraocular lens: three- and 5-year results of a randomized trial.
OBJECTIVE
To evaluate the long-term effects of anterior capsule polishing on regeneratory posterior capsule opacification (PCO), anterior capsule opacification (ACO), and fibrotic PCO with a silicone intraocular lens (IOL) with sharp optic edges.


METHODS
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.


METHODS
This prospective bilateral randomized patient- and examiner-masked clinical trial comprised 130 eyes of 65 patients with bilateral age-related cataract. All eyes had implantation of a 3-piece silicone IOL with a truncated, sharp-edged optic (CeeOn Edge 911A, Advanced Medical Optics). In 1 eye, the anterior capsule was extensively polished using an aspiration curette after phacoemulsification and cortex aspiration. Regenerative PCO was quantified objectively, while ACO and fibrotic PCO were graded subjectively 1, 2, 3, and 5 years postoperatively.


RESULTS
The mean ACO score was significantly lower in the eyes in which the anterior capsule had been polished (1 year, P<.02; 2 years, P<.03; 3 years, P<.01; 5 years, P<.01). The mean difference in regeneratory PCO and fibrotic PCO scores between the 2 groups was not statistically significant.


CONCLUSIONS
Three years after cataract surgery, eyes in which the anterior capsule had been polished had significantly less ACO. However, polishing did not lower PCO intensity when a sharp-edged CeeOn 911A IOL was implanted in the bag. Although results indicate that anterior capsule polishing may enhance the development of regeneratory PCO, this trend did not reach statistical significance.
Bolz
Matthias
M
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Menapace
Rupert
R
Findl
Oliver
O
Sacu
Stefan
S
Buehl
Wolf
W
Wirtitsch
Matthias
M
Leydolt
Christina
C
Kriechbaum
Katharina
K
D002386:Cataract / Q000209:etiology*; D004311:Double-Blind Method; D004847:Epithelial Cells / Q000473:pathology; D005355:Fibrosis / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology* / Q000601:surgery*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D012826:Silicone Elastomers; D013396:Suction / Q000379:methods*
D012826:Silicone Elastomers