Cardiac sarcoidosis with primary involvement of the tricuspid valve.
Sarcoid granulomas usually involve the myocardium with rare focal extensions into the pericardium and endocardium with resultant conduction defects, ventricular arrhythmias, and ventricular systolic and diastolic dysfunction. Primary involvement of valvular leaflets resulting in valvular regurgitation or stenosis is not known. We present a case of a wastewater consultant who developed tricuspid regurgitation and symptomatic atrioventricular block secondary to infiltration of tricuspid leaflets and conduction system from sarcoid granulomas. The patient later developed severe dilated cardiomyopathy as a result of extensive cardiac sarcoidosis necessitating cardiac transplantation. Valvular regurgitation should be included as one of the presenting manifestations of cardiac sarcoidosis.
Goyal
Sanjeev B
SB
Cardiac Electrophysiology, Department of Cardiology, Fallon Clinic, Worcester, Massachusetts 01608, USA. sangoy@pol.net
Aragam
Jayashri R
JR
D009202:Cardiomyopathies / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D006327:Heart Block / Q000473:pathology / Q000503:physiopathology; D006329:Heart Conduction System / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D014261:Tricuspid Valve / Q000473:pathology* / Q000503:physiopathology; D014262:Tricuspid Valve Insufficiency / Q000473:pathology / Q000503:physiopathology