title: Myc in model organisms: a view from the flyroom.
abstract: The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in Myc's physiological roles. In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development.
authors.affiliation: Department of Genetics & Development, Columbia University Medical Center, New York, NY 10032, USA.
authors.forename: Claire
authors.initials: C
authors.lastname: de la Cova
authors.forename: Laura A
authors.initials: LA
authors.lastname: Johnston
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D029721:Drosophila Proteins / Q000502:physiology*; D004331:Drosophila melanogaster / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D016271:Proto-Oncogene Proteins c-myc / Q000502:physiology*; D015398:Signal Transduction; D015534:Trans-Activators
chemical_list: D029721:Drosophila Proteins; D016271:Proto-Oncogene Proteins c-myc; D015534:Trans-Activators