Iodine assisted modified Suzuki type reaction of bicyclic hydrazines: stereoselective synthesis of functionalized cyclopentenes.
Bicyclic hydrazines undergo a facile palladium/iodine mediated stereoselective ring opening on reaction with organoboronic acids affording trans-3,4-disubstituted hydrazino cyclopentenes in good to excellent yield.
John
Jubi
J
Organic Chemistry Section, Chemical Sciences and Technology Division, Regional Research Laboratory (CSIR), Trivandrum, 695 019, Kerala, India.
Sajisha
V S
VS
Mohanlal
Smitha
S
Radhakrishnan
K V
KV