title: [Ghrelin - a novel appetite-stimulating hormone which also affects gastrointestinal functions].
abstract: Ghrelin, a novel gastrointestinal peptide with 28 amino acids, is secreted from the A-like cells of the gastric fundus. This peptide hormone does not only promote the release of growth hormone, but also stimulates food intake, gastric motility and cardiac output. Increased plasma ghrelin level has been reported in patients with upper gastrointestinal (GI) disease or in their disease animal model, suggesting its important role in the pathogenesis of upper GI disease.
authors.affiliation: Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. hsuzuki@sc.itc.keio.ac.jp
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Suzuki
authors.forename: Tatsuhiro
authors.initials: T
authors.lastname: Masaoka
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hibi
mesh_terms: D001066:Appetite / Q000502:physiology*; D003543:Cysteamine / Q000378:metabolism; D004415:Dyspepsia / Q000209:etiology; D004435:Eating; D005767:Gastrointestinal Diseases / Q000209:etiology*; D054439:Ghrelin / Q000502:physiology*; D006801:Humans; D010437:Peptic Ulcer / Q000209:etiology
chemical_list: D054439:Ghrelin; D003543:Cysteamine