Elevated CSF IL-6 in a patient with respiratory syncytial virus encephalopathy.
The patient was an 11-month-old boy who developed encephalopathy associated with respiratory syncytial virus bronchiolitis. Right hemispheric encephalopathy was indicated by left hemiparesis and a diffuse right hemispheric lesion detected with magnetic resonance imaging. Elevated levels of interleukin-6 in the cerebrospinal fluid during the acute phase suggested the involvement of increased production of one or more cytokines in the pathogenesis of viral related encephalopathy, similarly to that proposed for influenza encephalopathy.
Otake
Yuko
Y
Department of Pediatrics, Jichi Medical University, 3311-1 Yaksiji, Shimotsuke, Tochigi, Japan.
Yamagata
Takanori
T
Morimoto
Yasuko
Y
Imi
Mari
M
Mori
Masato
M
Aihara
Toshinori
T
Ichiyama
Takashi
T
Momoi
Mariko Y
MY
D001927:Brain Diseases / Q000821:virology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D007223:Infant; D015850:Interleukin-6 / Q000134:cerebrospinal fluid*; D008297:Male; D018357:Respiratory Syncytial Virus Infections / Q000134:cerebrospinal fluid*; D012136:Respiratory Syncytial Viruses; D013997:Time Factors
D015850:Interleukin-6