title: Nano-dispensing by electrospray for biotechnology.
abstract: Liquid transport of minute amounts of biomaterials is of paramount importance in many biotechnological applications. One of the challenges is the transport of viscous liquids without heating. Electro hydro dynamic atomization or electrospray is a viable method for the controlled transport of nanoliter volume of viscous liquids as shown for PEG400. Experimental results and the design of a novel spraying configuration, which can be incorporated in an optical microscope, are reported.
authors.affiliation: Biophysical Structure Chemistry, Leiden Institute for Chemistry, Leiden, The Netherlands. m.kuil@chem.leidenuniv.nl
authors.forename: Maxim E
authors.initials: ME
authors.lastname: Kuil
authors.forename: Jan Pieter
authors.initials: JP
authors.lastname: Abrahams
authors.forename: Jan C M
authors.initials: JC
authors.lastname: Marijnissen
mesh_terms: D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D003460:Crystallization; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D008832:Microchemistry / Q000295:instrumentation / Q000379:methods; D046210:Microfluidic Analytical Techniques; D044085:Microfluidics; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D011506:Proteins / Q000737:chemistry
chemical_list: D011506:Proteins