title: Solitary pulmonary metastasis arising thirteen years after liver transplantation for HBV-related hepatocellular carcinoma.
abstract: We described a 59-year-old male patient who underwent liver transplantation in 1989 for hepatocellular carcinoma (HCC) complicating hepatitis B virus (HBV) cirrhosis. In 2001 (12 years after liver transplantation), he developed a lung metastasis of HCC without intrahepatic recurrence and the resection was done. In July 2003, he was symptom free without any recurrence. HCC metastasis can develop even after a very long time of liver transplantation. Many HCCs grow slowly, and the growth rate of recurrent tumors in patients receiving immunosuppressive therapy is significantly greater than that of those who do not receive immunosuppressive therapy.
authors.affiliation: Service d'Hépatologie, INSERM CRB3, University of Paris VII, Hôpital, Beaujon, Clichy 92 110, France.
authors.forename: Chiara
authors.initials: C
authors.lastname: Viola
authors.forename: Tarik
authors.initials: T
authors.lastname: Asselah
authors.forename: Didier
authors.initials: D
authors.lastname: Samuel
authors.forename: François
authors.initials: F
authors.lastname: Durand
authors.forename: Hamza
authors.initials: H
authors.lastname: Boudjema
authors.forename: Dominique
authors.initials: D
authors.lastname: Valla
authors.forename: Patrick
authors.initials: P
authors.lastname: Marcellin
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000209:etiology / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D005355:Fibrosis / Q000150:complications / Q000209:etiology / Q000821:virology; D006509:Hepatitis B / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D006515:Hepatitis B virus / Q000378:metabolism; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D016031:Liver Transplantation; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012008:Recurrence