title: FDG positron emission tomography/computerized tomography features of bleomycin-induced pneumonitis.
abstract: Bleomycin is a widely used chemotherapeutic that has been shown to induce life-threatening interstitial lung disease in a small subset of patients. We report a case of bleomycin-induced pneumonitis in a patient treated for Hodgkin lymphoma with severe clinical respiratory symptoms, a marked restrictive pattern on pulmonary function tests, and FDG avid lymphadenopathy and diffuse increased uptake involving both lungs on imaging. To our knowledge, the in-line computed tomography/18F-fluorodeoxyglucose positron emission tomography of bleomycin induced pneumonitis has not been previously reported in the literature.
authors.affiliation: The Cleveland Clinic Foundation, 9500 Euclid Avenue/Hb6, Cleveland, OH 44195, USA. kirschj@ccf.org
authors.forename: Jacobo
authors.initials: J
authors.lastname: Kirsch
authors.forename: Andrea V
authors.initials: AV
authors.lastname: Arrossi
authors.forename: John K
authors.initials: JK
authors.lastname: Yoon
authors.forename: Guiyun
authors.initials: G
authors.lastname: Wu
authors.forename: Donald R
authors.initials: DR
authors.lastname: Neumann
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D006689:Hodgkin Disease / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D000903:Antibiotics, Antineoplastic; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D001761:Bleomycin