Septic shock and multi-organ failure in HIV infection-'sepsis tuberculosa gravissima'.
A profoundly immunosuppressed HIV-infected man developed sepsis syndrome with multi-organ failure. A septic screen failed to identify a bacterial or fungal cause and despite empirical treatment for these pathogens the patient remained unwell. Investigations revealed disseminated tuberculosis. With specific anti-tuberculosis therapy the patient rapidly recovered. Although most cases of sepsis syndrome in HIV-infected patients are due to bacteria, tuberculosis should be added to the differential diagnosis of this presentation.
Ferrand
Rashida A
RA
University College Hospital, London NW1 2BU, UK.
Herman
Joanna
J
Elgalib
Ali
A
Cartledge
Jonathan
J
Miller
Robert F
RF
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D006678:HIV; D015658:HIV Infections / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000382:microbiology* / Q000821:virology*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D012772:Shock, Septic / Q000382:microbiology* / Q000821:virology*; D014397:Tuberculosis, Pulmonary / Q000382:microbiology / Q000821:virology*