title: Positive selection in the ComC-ComD system of Streptococcal Species.
abstract: Competence-stimulating peptide (CSP) and ComD of the streptococcal species are a pheromone and its receptor, respectively, involved in the regulation of competence for natural genetic transformation. We show here that these molecules have undergone positive selection. This study is the first report of positive selection due to competition among bacterial populations.
authors.affiliation: Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan. ichihara@kuicr.kyoto-u.ac.jp
authors.forename: Hisako
authors.initials: H
authors.lastname: Ichihara
authors.forename: Kei-ichi
authors.initials: K
authors.lastname: Kuma
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Toh
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D010675:Pheromones / Q000235:genetics*; D012641:Selection, Genetic; D016415:Sequence Alignment; D013291:Streptococcus / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D010675:Pheromones; C423628:competence factor, Streptococcus