title: Enantioselective transfer aminoallylation: synthesis of optically active homoallylic primary amines.
abstract: A camphorquinone-derived chiral homoallylic amine was found to react with various aldehydes via imine formation and asymmetric 2-azonia-Cope rearrangement to give optically active homoallylic primary amines. A practical level of enantioselectivity with high functional group tolerance has been attained in this transformation.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Sugiura
authors.forename: Chieko
authors.initials: C
authors.lastname: Mori
authors.forename: Shu
authors.initials: S
authors.lastname: Kobayashi
mesh_terms: D000588:Amines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000588:Amines