title: [Advance of study on pathological mechanism of paraquat poisoning].
abstract: Paraquat which is used widely as a potent herbicide is poisonous, and its pathological mechanism is unclear. Studies show that it is so a strong oxidant that it can oxidate lipid and some enzyme, also, it can damage DNA directly or induce necrosis or apoptosis, which is marked in pulmonary. To offer new directions for treatment and studies on paraquat poisoning, this paper reviewed the foreign studies on mechanism of it.
authors.affiliation: West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Wang
authors.forename: Bo
authors.initials: B
authors.lastname: Jin
authors.forename: Min
authors.initials: M
authors.lastname: Liu
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Liao
mesh_terms: D000818:Animals; D004249:DNA Damage; D006540:Herbicides / Q000506:poisoning*; D006801:Humans; D010269:Paraquat / Q000506:poisoning*; D011041:Poisoning / Q000201:enzymology / Q000235:genetics / Q000503:physiopathology
chemical_list: D006540:Herbicides; D010269:Paraquat