title: Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement.
abstract: Adult-onset copper deficiency with neurological manifestations is a newly recognised syndrome. Long-term oral copper replacement therapy has been the mainstay of treatment in the literature. A case of relapsing hypocupraemic myelopathy responsive to increased doses of copper replacement is reported. Standard doses of copper may not be sufficient for all patients.
authors.affiliation: Department of Neurology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA. calin-prodan@ouhsc.edu
authors.forename: C I
authors.initials: CI
authors.lastname: Prodan
authors.forename: S S
authors.initials: SS
authors.lastname: Bottomley
authors.forename: N R
authors.initials: NR
authors.lastname: Holland
authors.forename: S E
authors.initials: SE
authors.lastname: Lind
mesh_terms: D003300:Copper / Q000172:deficiency* / Q000627:therapeutic use*; D003677:Deficiency Diseases / Q000150:complications; D005260:Female; D006801:Humans; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000188:drug therapy* / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D003300:Copper