title: Influence of concomitant coronary artery bypass graft on outcome of surgery of the ascending aorta/arch.
abstract: BACKGROUND
  Surgery of the ascending aorta with or without arch is being performed in an increasingly elderly population with risks of coexisting coronary artery disease.
  
  
  OBJECTIVE
  To define specific groups requiring coronary artery bypass graft (CABG) and to analyse the influence of concomitant CABG on outcome.
  
  
  METHODS
  Over a 10-year period in a single institution, 296 consecutive procedures on the ascending aorta with or without arch were carried out in 291 patients. CABG was required in 42 (14.2%) procedures. In 24 (57%) patients, CABG was planned preoperatively and in 18 (43%) patients, on a salvage basis.
  
  
  RESULTS
  In-hospital mortality for patients undergoing concomitant CABG was higher (21.4% v 11%, p<0.06). Adjusting for baseline and operative characteristics, this was attributable to operative priority, and was not a consequence of concomitant CABG (adjusted OR 0.30, 95% CI 1.1 to 8.31; p = 0.48). However, in-hospital mortality was significantly higher when CABG was performed as salvage rather than as a planned procedure (38.9% v 8.9%, p = 0.025), and this difference remained after adjusting for confounding variables (adjusted OR 16.2, 95% CI 1.03 to >200; p = 0.047). The 3-year survival was significantly lower with concomitant CABG (59% v 81.9%, p<0.001).
  
  
  CONCLUSIONS
  In association with surgery of the ascending aorta with or without arch planned concomitant CABG did not entail any added operative risk. However, salvage CABG, which occurred almost exclusively in association with emergency cases, was associated with a higher early mortality. Patients needing concomitant CABG had worse survival at 3 years compared with those requiring isolated surgery of the ascending aorta with or without arch.
authors.affiliation: Bristol Heart Institute, Bristol Royal Infirmary, Bristol BS2 8HW, UK.
authors.forename: P
authors.initials: P
authors.lastname: Narayan
authors.forename: C A
authors.initials: CA
authors.lastname: Rogers
authors.forename: M
authors.initials: M
authors.lastname: Caputo
authors.forename: G D
authors.initials: GD
authors.lastname: Angelini
authors.forename: A J
authors.initials: AJ
authors.lastname: Bryan
mesh_terms: D000368:Aged; D001011:Aorta / Q000601:surgery*; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001015:Aortic Arch Syndromes / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001027:Aortography; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D016879:Salvage Therapy; D015996:Survival Rate; D016896:Treatment Outcome