title: Olanzapine for recurrent excessive irritability and psychotic symptoms after mesial temporal lobectomy in a patient with temporal lobe epilepsy.
abstract: We report the case of a patient with temporal lobe epilepsy, nonresponsive to antiepileptic drugs, who became seizure-free, but developed recurrent excessive irritability and psychotic symptoms after successful mesial temporal lobectomy. This patient was refractory to various pharmacological treatments including antipsychotics, mood stabilizers, and benzodiazepines before being successfully treated with olanzapine.
authors.affiliation: Department of Psychiatry, Raul Soares Institute, Belo Horizonte, Brazil.
authors.forename: Maila de Castro Lourenço
authors.initials: MC
authors.lastname: das Neves
authors.forename: Mirian Fabíola Studart Gurgel
authors.initials: MF
authors.lastname: Mendes
authors.forename: Andréa Julião
authors.initials: AJ
authors.lastname: de Oliveira
authors.forename: Erika Machado
authors.initials: EM
authors.lastname: Viana
authors.forename: Aila
authors.initials: A
authors.lastname: de Guadalupe
authors.forename: Hélio Lauar
authors.initials: HL
authors.lastname: de Barros
authors.forename: Jaime Eduardo Cecílio
authors.initials: JE
authors.lastname: Hallak
authors.forename: José Maurício
authors.initials: JM
authors.lastname: Siqueira
authors.forename: João Vinícius
authors.initials: JV
authors.lastname: Salgado
mesh_terms: D000328:Adult; D038481:Anterior Temporal Lobectomy; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology; D000077152:Olanzapine; D011183:Postoperative Complications / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine