Activity of 11beta-hydroxysteroid dehydrogenase in tissues of hypertensive NISAG rats.
11beta-Hydroxysteroid dehydrogenase activity in the kidneys of NISAG rats (rat strain with hereditary stress-induced arterial hypertension) was 1.5-fold higher than in WAG rats. An inverse relationship was observed in the liver of these animals. After stress exposure 11beta-hydroxysteroid dehydrogenase activity remained unchanged in the kidneys of NISAG and WAG rats, but significantly increased in the liver of NISAG rats. Functional activity of 11beta-hydroxysteroid dehydrogenase probably reflects the hypertensive state of NISAG rats.
Cherkasova
O P
OP
Institute of Laser Physics, Siberian Division of the Russian Academy of Sciences, Novosibirsk. chrom@laser.nsc.ru
D042842:11-beta-Hydroxysteroid Dehydrogenases / Q000032:analysis*; D000818:Animals; D003345:Corticosterone / Q000097:blood; D006973:Hypertension / Q000175:diagnosis* / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D042842:11-beta-Hydroxysteroid Dehydrogenases; D003345:Corticosterone