Synthesis of taiwaniaquinoids via Nazarov triflation.
A unified approach toward the taiwaniaquinoids that has yielded four natural products is described. A new variant of the Nazarov reaction with concomitant formation of an enol triflate serves as one of the key steps, considerably shortening the synthetic scheme and providing a general entry into this class of bioactive natural products.
Liang
Guangxin
G
Department of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, USA.
Xu
Yue
Y
Seiple
Ian B
IB
Trauner
Dirk
D
D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction
D004224:Diterpenes