Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease.
The authors report an improvement in delusions and hallucinations after antidepressant treatment (Clomipramine) in a parkinsonian patient with psychosis and comorbid depression. Their findings, which support a previous case treated with Citalopram, highlight the possible effectiveness of antidepressant therapy on psychotic symptoms in parkinsonian patients.
Meco
Giuseppe
G
Dipartimento di Scienze Neurologiche, Università di Roma La Sapienza, Viale dell'Università 30, 00185 Roma, Italy. giuseppe.meco@uniroma1.it
Bernardi
Silvia
S
D000339:Affect / Q000187:drug effects; D000928:Antidepressive Agents / Q000627:therapeutic use*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002997:Clomipramine / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use; D003702:Delusions / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D006212:Hallucinations / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D010479:Pergolide / Q000627:therapeutic use; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications / Q000188:drug therapy* / Q000523:psychology
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D010479:Pergolide; D007980:Levodopa; D003024:Clozapine; D002997:Clomipramine