title: A new sesquiterpene lactone glucoside with inhibitory effect on K562 cells from Ixeris sonchifolia (Bge) Hance.
abstract: A new minor sesquiterpene lactone glucoside, ixerin ZA (1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-[6'-(p-metheoxyphenylacetyl)]-beta-glucopyranoside on the basis of spectroscopic and chemical evidence. Compound 1 exhibited an inhibitory effect on K562 cells.
authors.affiliation: School of Pharmacy, Wenzhou Medical College, Wenzhou 325035, China.
authors.forename: W-F
authors.initials: WF
authors.lastname: He
authors.forename: B-B
authors.initials: BB
authors.lastname: Xu
authors.forename: J-C
authors.initials: JC
authors.lastname: Pan
authors.forename: J-C
authors.initials: JC
authors.lastname: Lu
authors.forename: S-J
authors.initials: SJ
authors.lastname: Song
authors.forename: S-X
authors.initials: SX
authors.lastname: Xu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D006868:Hydrolysis; D020014:K562 Cells; D007783:Lactones / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D007783:Lactones; D012717:Sesquiterpenes; C514639:ixerin ZA