Novel approaches to the diagnosis of fetal alcohol spectrum disorder.
The diagnosis of fetal alcohol spectrum disorder is a difficult task, especially in cases where clear, physical markers of in utero alcohol exposure are not apparent. Reviewed in the following paper are some older tools for screening alcohol use in pregnancy and present novel approaches to the diagnosis of FASD, including ethanol biomarker development to behavioural phenotyping. Improving current FASD diagnostic methodology through more novel approaches may provide the possibility of earlier and wider diagnosis, allowing intervention and treatment at stages where the advanced effects of alcohol can still be mitigated.
Caprara
Daniela L
DL
Division of Clinical Pharmacology/Toxicology and Motherisk Program, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ont., Canada M5G 1X8.
Nash
Kelly
K
Greenbaum
Rachel
R
Rovet
Joanne
J
Koren
Gideon
G
D000438:Alcohols; D001526:Behavioral Symptoms; D015415:Biomarkers; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000175:diagnosis* / Q000503:physiopathology; D006197:Hair / Q000473:pathology; D006801:Humans; D008297:Male; D008470:Meconium / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000175:diagnosis* / Q000503:physiopathology; D011795:Surveys and Questionnaires
D000438:Alcohols; D015415:Biomarkers