[Clinical study on Dan Shao Tang in treating diabetic nephropathy of deficiency of Yin with damp-heat symptom].
OBJECTIVE
To explore the effect of Dan Shao Tang (DST) in treating diabetic nephropathy (DN) of deficiency of Yin with damp-heat symptom.


METHODS
The 72 patients with DN of deficieny of Yin with damp-heat symptom were randomly divided into two groups. Among them, the 42 patients in treatment group were treated with DST and western medicine and the 30 patients in control group were treated only with western medicine. Before and after treatment, the effect and indexes change including blood glucose, renal function, proteinuria, microproteins, lipid metabolism and hyperviscosity were observed.


RESULTS
After three months treatment, the general effective rate in treatment group was 76.19%, which was markedly higher than that in control group (50.00%, P < 0.01). Moreover, treatment group was obviously better than control group on decreasing blood glucose proteinuria and microproteins, improving renal function, ameliorating lipuid metabolism and hyperviscosity (P < 0.01 or P < 0.05).


CONCLUSIONS
DST is effective ton treatment on DN of deficiency of Yin with damp-heat symptom.
Wu
Xin-Lin
XL
Department of Traditional Chinese Medicine, First Affiliated Hospital of Sun Yet-sen University, Guangzhou 510080, China.
Li
Jun-Biao
JB
Ao
Qin-Xing
QX
Zhang
Wei-Jun
WJ
Liu
Ben-Liu
BL
Shen
Wei-Zeng
WZ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000187:drug effects; D001809:Blood Viscosity; D003928:Diabetic Nephropathies / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D016710:Yin Deficiency / Q000188:drug therapy*
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal