Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature.
Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 year later a gastric recurrence of RCC treated 10 years ago with a resection and interleukin-2 (IL-2). Accumulating evidence indicates that metastatic involvement of the pancreas and stomach should be suspected in any patient with a history of RCC who presents with gastrointestinal symptoms even 10 years after RCC resection and immunotherapy.
Riviello
Chiara
C
Second Division of General and Vascular Surgery, Careggi Hospital, Florence, Italy. chiarariviello@libero.it
Tanini
Ilaria
I
Cipriani
Greta
G
Pantaleo
Pietro
P
Nozzoli
Carlo
C
Poma
Alberto
A
Riccardo
Viligiardi
V
Valeri
Andrea
A
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy; D007376:Interleukin-2 / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy*; D008297:Male; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000556:secondary; D012008:Recurrence; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000556:secondary
D007376:Interleukin-2