title: Disseminated mucormycosis in haematological patients: CT and MRI findings with pathological correlation.
abstract: Disseminated mucormycosis is a rare, mostly fatal infectious complication in immunocompromised haematological patients. The purpose of our study was to describe the multiorgan manifestations of disseminated mucormycosis documented at CT and MRI in four patients and correlate these with the pathological findings and patient outcome. Irrespective of the site of infection, infarction or haemorrhage are the constant features of invasive mycosis. Identification of one or both of these two major imaging findings in immunocompromised patients should be regarded as an indicator of possible infection by angiotropic fungi, including the genre Mucorales.
authors.affiliation: Department of Diagnostic Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076 Tübingen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Horger
authors.forename: H
authors.initials: H
authors.lastname: Hebart
authors.forename: H
authors.initials: H
authors.lastname: Schimmel
authors.forename: M
authors.initials: M
authors.lastname: Vogel
authors.forename: H
authors.initials: H
authors.lastname: Brodoefel
authors.forename: K
authors.initials: K
authors.lastname: Oechsle
authors.forename: U
authors.initials: U
authors.lastname: Hahn
authors.forename: M
authors.initials: M
authors.lastname: Mittelbronn
authors.forename: W
authors.initials: W
authors.lastname: Bethge
authors.forename: C D
authors.initials: CD
authors.lastname: Claussen
mesh_terms: D000328:Adult; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D009101:Multiple Myeloma / Q000601:surgery; D009894:Opportunistic Infections / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000601:surgery; D014057:Tomography, X-Ray Computed