Wernicke's encephalopathy: beyond alcoholism.
BACKGROUND
A 17-year-old pregnant woman presented to hospital at 19 weeks' gestation with an 8-week history of hyperemesis gravidarum, 16.8 kg of weight loss, and new-onset weakness, dizziness and blurred vision. Examination of the patient showed confusion, papilledema, ophthalmoparesis, nystagmus, reduced hearing and truncal ataxia.


METHODS
Physical examination, abdominal ultrasound, fetal ultrasound, brain MRI, magnetic resonance angiography, magnetic resonance venography and cerebrospinal-fluid analysis.


METHODS
Wernicke's encephalopathy, hyperemesis gravidarum and fetal loss.


RESULTS
Intravenous thiamine repletion and elimination of deficiency risk factors.
Wilson
Robin K
RK
Department of Neurology, Johns Hopkins University, Baltimore, MD 21287-7519, USA.
Kuncl
Ralph W
RW
Corse
Andrea M
AM
D000032:Abortion, Therapeutic; D000293:Adolescent; D005260:Female; D005313:Fetal Death / Q000000981:diagnostic imaging; D006801:Humans; D006939:Hyperemesis Gravidarum; D008279:Magnetic Resonance Imaging; D009460:Neurologic Examination; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000473:pathology; D013788:Thalamus / Q000473:pathology; D013831:Thiamine / Q000627:therapeutic use; D014463:Ultrasonography; D014815:Vitamins / Q000627:therapeutic use; D014899:Wernicke Encephalopathy / Q000150:complications / Q000175:diagnosis* / Q000473:pathology
D014815:Vitamins; D013831:Thiamine