title: Chemical constituents from the peels of Citrus sudachi.
abstract: A methanol extract of the peels of Citrus sudachi gave five new compounds (1-5) and 27 known compounds. The structures were elucidated on the basis of spectroscopic evidence. Several of these compounds were assayed for antimicrobial activity against methicillin-resistant Staphylococcus aureus and Helicobacter pylori, and sudachitin (6) and 3'-demethoxysudachitin (7) were the most active.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi, 1-78, Tokushima 770-8505, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Takaishi
authors.forename: Naonobu
authors.initials: N
authors.lastname: Tanaka
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Shibata
authors.forename: Tomihiko
authors.initials: T
authors.lastname: Higuti
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002957:Citrus / Q000737:chemistry*; D003373:Coumaric Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects; D007564:Japan; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016106:Methicillin Resistance / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D003373:Coumaric Acids; D005419:Flavonoids; D006027:Glycosides; D036701:Limonins; C513626:sudachitin; C004999:ferulic acid