title: Pulmonary blastomycosis masquerading as metastatic disease in the lung: a case report.
abstract: We report a case of pulmonary blastomycosis appearing as metastatic laryngeal squamous cell carcinoma. Pulmonary blastomycosis was discovered as right lower lobe subpleural activity consistent with metastatic disease on a positron emission tomographic (PET) scan following total laryngectomy and bilateral neck dissection for locally invasive laryngeal squamous cell carcinoma. A computed tomographic (CT) scan of the chest showed a right lower lobe, subpleural pulmonary nodule. CT-guided fine-needle aspiration of the nodule revealed broad-based budding yeast consistent with blastomycosis. To our knowledge, this is the first case of a PET-positive pulmonary blastomycosis lesion mimicking pulmonary malignancy reported in the literature.
authors.affiliation: Thomas Jefferson University, Philadelphia, Pennsylvania, USA. bobbak.vahid@mail.tju.edu
authors.forename: Bobbak
authors.initials: B
authors.lastname: Vahid
authors.forename: Bernadette
authors.initials: B
authors.lastname: Wildemore
authors.forename: Christopher
authors.initials: C
authors.lastname: Nguyen
authors.forename: Niki
authors.initials: N
authors.lastname: Sistrun
authors.forename: Paul E
authors.initials: PE
authors.lastname: Marik
mesh_terms: D000368:Aged; D001759:Blastomycosis / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D008297:Male; D049268:Positron-Emission Tomography