title: Clinical presentation of intraocular lens schisis.
abstract: OBJECTIVE
  To analyze the clinical presentation and implications of cavity or schisis formation in the MemoryLens (CIBA Vision) intraocular lens (IOL) optic.
  
  
  METHODS
  Eye Department, Red Cross Hospital, Munich, Germany.
  
  
  METHODS
  This study was a retrospective chart review and slitlamp photography analysis of IOL schisis.
  
  
  RESULTS
  Four patients with IOL schisis were identified and their charts analyzed. Clinically, the schisis presented as a sharply demarcated round structure. The aspect was clear on coaxial illumination, but on tangential illumination the schisis area was opaque. Patients experienced glare, foggy vision, and deteriorated visual function or had no symptoms. One patient lost visual acuity, and the IOL was explanted.
  
  
  CONCLUSIONS
  Clinically, IOL schisis was easily differentiated from cases of IOL opacification due to calcification. The clinical implication was not uniform, ranging from no symptoms to great visual disturbance leading to explantation of the IOL. The cause of this complication remains unclear. A possible explanation is the impact of solvent-induced tensile stress on the IOL optic material during the manufacturing process.
authors.affiliation: University Eye Hospital Tuebingen, Tuebingen, Germany. irmingard.neuhann@med.uni-tuebingen.de
authors.forename: Irmingard M
authors.initials: IM
authors.lastname: Neuhann
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Neuhann
authors.forename: Guy
authors.initials: G
authors.lastname: Kleinmann
authors.forename: David J
authors.initials: DJ
authors.lastname: Apple
mesh_terms: D000368:Aged; D020878:Device Removal; D005260:Female; D019466:Glare; D006801:Humans; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D011475:Prosthesis Failure; D012086:Reoperation; D012189:Retrospective Studies; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity