Tubulointerstitial nephritis and uveitis syndrome.
Tubulointerstitial nephritis and uveitis syndrome is likely underdiagnosed. A 13-year-old girl with no significant medical history had photophobia, ocular pain, and decreased visual acuity. Bilateral papilledema was present. Renal biopsy revealed interstitial nephritis. Immunosuppressive therapy was added (3 mg/kg/d of cyclosporine). One year later, visual acuity was 20/20 and findings were normal on ocular examination and laboratory tests.
Guerriero
Silvana
S
Dipartimento di Oftalmologia e Otorinolaringoiatria, Division of Ophthalmology, University of Bari, Bari, Italy.
Vischi
Antonio
A
Giancipoli
Giovanni
G
Leozappa
Marco
M
Ferrari
Tommaso Micelli
TM
D000293:Adolescent; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D009395:Nephritis, Interstitial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010211:Papilledema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D013577:Syndrome; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D008775:Methylprednisolone