Erythrokeratoderma variabilis successfully treated with topical tazarotene.
Erythrokeratoderma variabilis, also known as Mendes da Costa syndrome, is a genodermatosis belonging to the group of diseases known as the erythrokeratodermias. Erythrokeratoderma variabilis is characterized by two distinctive manifestations: well-demarcated, variable, transient, figurate patches of erythema, and localized or generalized hyperkeratotic plaques. Treatments include topical retinoic acid, salicylic acid, and alpha-hydroxy acid in petrolatum, but all have been reported to have limited, variable success rates. We report a child with erythrokeratoderma variabilis with no family history of this entity, successfully treated with topical tazarotene.
Yoo
Stephen
S
Department of Dermatology, University of Texas Southwestern, Dallas, Texas, USA.
Simzar
Soheil
S
Han
Karen
K
Takahashi
Stefani
S
Cotliar
Ronald
R
D002675:Child, Preschool; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004890:Erythema / Q000188:drug therapy*; D006801:Humans; D017488:Hyperkeratosis, Epidermolytic / Q000188:drug therapy*; D008297:Male; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome; D012176:Retinoids
D003879:Dermatologic Agents; D009539:Nicotinic Acids; C086827:tazarotene; D012176:Retinoids