title: Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi.
authors.affiliation: Wolfson Centre for Structure-Based Design of Molecular Diagnostics, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester M13 9PL, UK.
authors.forename: João
authors.initials: J
authors.lastname: Neres
authors.forename: Alejandro
authors.initials: A
authors.lastname: Buschiazzo
authors.forename: Pedro M
authors.initials: PM
authors.lastname: Alzari
authors.forename: Lindsey
authors.initials: L
authors.lastname: Walsh
authors.forename: Kenneth T
authors.initials: KT
authors.lastname: Douglas
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000032:analysis*; D005470:Fluorometry / Q000379:methods*; D006023:Glycoproteins / Q000037:antagonists & inhibitors*; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D014349:Trypanosoma cruzi / Q000201:enzymology*
chemical_list: D004791:Enzyme Inhibitors; D006023:Glycoproteins; C069715:trans-sialidase; D009439:Neuraminidase