Aberrant expression of perilipins and 11-beta-HSD-1 as molecular signatures of metabolic syndrome X in south east Asians.
Metabolics syndrome is common in SE Asian. An hypothesis that aberrant expression of perilipins and 11-beta-hydroxysteroid dehydrogenase-1 (11-beta-HSD-1) enzyme plays a significant role in the development of metabolic syndrome X in Indians is proposed. Thus, methods designed to target perilipins and 11-beta-HSD-1 may form a novel approach in the prevention and management of metabolic syndrome X.
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UND Life Sciences, 13800 Fairhill Road, #321, Shaker Heights, OH 44120, USA.
D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1 / Q000378:metabolism*; D044466:Asian People; D002352:Carrier Proteins; D006801:Humans; D024821:Metabolic Syndrome / Q000378:metabolism*; D000070778:Perilipin-1; D010750:Phosphoproteins / Q000378:metabolism*
D002352:Carrier Proteins; D000070778:Perilipin-1; D010750:Phosphoproteins; D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1