title: [Treatment of pediatric malaria in Africa: act at issue].
abstract: Artemisinin-based combination therapies (ACT) have been proposed as alternatives to currently used antimalarials and are poised large-scale deployment in Africa. These combinations are particularly attractive for managing malaria in children. Expected benefits of ACT include enhanced efficacy, rapid action, stabilized antimalarial resistance growth and lower malaria transmission. This article discusses what can be reasonably expected of ACT in an African setting with emphasis on patient comfort.
authors.affiliation: Service des maladies infectieuses et tropicales, CHU de Besançon, France. jjfaucher@chu-besancon.fr
authors.forename: J F
authors.initials: JF
authors.lastname: Faucher
authors.forename: M A
authors.initials: MA
authors.lastname: Missinou
authors.forename: P
authors.initials: P
authors.lastname: Brasseur
mesh_terms: D000962:Antimalarials / Q000627:therapeutic use*; D037621:Artemisinins / Q000627:therapeutic use*; D002675:Child, Preschool; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D008288:Malaria / Q000188:drug therapy* / Q000635:transmission; D017060:Patient Satisfaction
chemical_list: D000962:Antimalarials; D037621:Artemisinins