title: Fulminant septicaemia caused by multi-drug-resistant Streptococcus mitis following unrelated cord blood transplantation.
abstract: Streptococcus mitis (a common and usually harmless bacterium found in the nose, mouth and throat) can have an unusually high level of resistance to beta-lactam antibiotics. We report a patient who developed fatal Streptococcus mitis septicaemia following unrelated cord blood transplantation. Administration of vancomycin to patients with recurrent fever during allogeneic stem cell transplantation might be indicated.
authors.affiliation: Division of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Taiwan, Republic of China.
authors.forename: Shih-Hsiang
authors.initials: SH
authors.lastname: Chen
authors.forename: Chao-Ping
authors.initials: CP
authors.lastname: Yang
authors.forename: Cheng-Hsun
authors.initials: CH
authors.lastname: Chiu
authors.forename: Ju-Hsin
authors.initials: JH
authors.lastname: Chia
authors.forename: I-Anne
authors.initials: IA
authors.lastname: Huang
authors.forename: Tang-Her
authors.initials: TH
authors.lastname: Jaing
mesh_terms: D002648:Child; D024901:Drug Resistance, Multiple, Bacterial; D017809:Fatal Outcome; D005260:Female; D005312:Fetal Blood / Q000637:transplantation*; D006801:Humans; D018805:Sepsis / Q000209:etiology* / Q000382:microbiology; D013290:Streptococcal Infections / Q000209:etiology* / Q000382:microbiology; D034361:Streptococcus mitis / Q000187:drug effects* / Q000302:isolation & purification; D065227:Transfusion Reaction; D017086:beta-Thalassemia / Q000628:therapy