title: Representation of interaural time delay in the human auditory midbrain.
abstract: Interaural time difference (ITD) is a critical cue to sound-source localization. Traditional models assume that sounds leading at one ear, and perceived on that side, are processed in the opposite midbrain. Using functional magnetic resonance imaging we demonstrate that as the ITDs of sounds increase, midbrain activity can switch sides, even though perceived location remains on the same side. The data require a new model for human ITD processing.
authors.affiliation: Department of Physiology and UCL Ear Institute, University College London, 332 Gray's Inn Road, London WC1X 8EE, UK.
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Thompson
authors.forename: Katharina
authors.initials: K
authors.lastname: von Kriegstein
authors.forename: Adenike
authors.initials: A
authors.lastname: Deane-Pratt
authors.forename: Torsten
authors.initials: T
authors.lastname: Marquardt
authors.forename: Ralf
authors.initials: R
authors.lastname: Deichmann
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Griffiths
authors.forename: David
authors.initials: D
authors.lastname: McAlpine
mesh_terms: D000161:Acoustic Stimulation; D001306:Auditory Pathways / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D003463:Cues; D004423:Ear / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008636:Mesencephalon / Q000502:physiology*; D008959:Models, Neurological; D013017:Sound Localization / Q000502:physiology*; D013997:Time Factors