title: Severe kyphoscoliosis associated with osteomalacia.
abstract: BACKGROUND
  Kyphoscoliosis is one of the most frequent complications of osteomalacia, which only rarely results in severe deformity requiring surgery. To the best of our knowledge, there has been only one previous report of a spinal deformity as a complication of osteomalacia that was sufficiently severe so as to require surgical treatment.
  
  
  OBJECTIVE
  To report here the case of a 27-year-old woman who experienced back pain of gradual onset accompanied by progressive scoliosis resulting in severe dyspnea.
  
  
  METHODS
  A case report.
  
  
  METHODS
  She was diagnosed with hypophosphatemic osteomalacia and secondary hyperparathyroidism. She underwent posterior surgical correction and fusion from Th4-L1 using the ISOLA spinal system.
  
  
  RESULTS
  At the last follow-up (3 year and 9 months postoperatively), her body balance was good and the dyspnea had disappeared. Plain radiographs demonstrated no loss of correction and also showed no evidence of instrumentation failure.
  
  
  CONCLUSIONS
  We present a unique instance of a young woman with severe kyphoscoliosis who underwent posterior surgical correction/fusion with spinal instrumentation.
authors.affiliation: Department of Orthopaedic Surgery, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama, 359-8513, Japan. tmotosuneya@yahoo.co.jp
authors.forename: Takao
authors.initials: T
authors.lastname: Motosuneya
authors.forename: Takashi
authors.initials: T
authors.lastname: Asazuma
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yasuoka
authors.forename: Takashi
authors.initials: T
authors.lastname: Tsuji
authors.forename: Kyosuke
authors.initials: K
authors.lastname: Fujikawa
mesh_terms: D000328:Adult; D004417:Dyspnea / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D010018:Osteomalacia / Q000150:complications / Q000473:pathology*; D012600:Scoliosis / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D013123:Spinal Fusion / Q000295:instrumentation