title: Congenital osteofibrous dysplasia associated with pseudoarthrosis of the tibia and fibula.
abstract: The association between congenital pseudoarthrosis and osteofibrous dysplasia of the tibia and fibula is a rare entity that has been recently recognized. We report a male newborn who was found to have swelling and deformity of the left lower leg. Radiographs and magnetic resonance imaging showed an extensive destructive lesion of the tibial shaft, with dysplastic congenital pseudoarthrosis of the lower fibula. Histopathological examination confirmed the diagnosis of congenital pseudoarthrosis of the tibia and fibula with underlying osteofibrous dysplasia involving both bones. Immunohistochemical stains showed cytokeratin positivity.
authors.affiliation: Department of Diagnostic Imaging, KK Women's and Children's Hospital, 100 Bukit Timah Road, 229899 Singapore.
authors.forename: Harvey E L
authors.initials: HE
authors.lastname: Teo
authors.forename: Wilfred C G
authors.initials: WC
authors.lastname: Peh
authors.forename: M
authors.initials: M
authors.lastname: Akhilesh
authors.forename: S B
authors.initials: SB
authors.lastname: Tan
authors.forename: T
authors.initials: T
authors.lastname: Ishida
mesh_terms: D005357:Fibrous Dysplasia of Bone / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery; D005360:Fibula / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D011542:Pseudarthrosis / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery; D013977:Tibia / Q000002:abnormalities*