Homocysteine.
Elevated homocysteine levels are associated with a variety of vascular diseases. Specifically, hyperhomocysteinemia is a risk factor for coronary artery disease, cerebrovascular disease, and peripheral arterial disease. Laboratory-based strategies for its detection and quantification have evolved to meet the increasing need for accuracy in risk prediction. Although new technologies have been developed over the past 2 decades that have enhanced the precision of measurement, universal guidelines for circulating homocysteine determination remain lacking.
Maron
Bradley A
BA
Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Loscalzo
Joseph
J
D000818:Animals; D002318:Cardiovascular Diseases / Q000378:metabolism; D002561:Cerebrovascular Disorders / Q000378:metabolism; D002849:Chromatography, Gas / Q000592:standards; D002851:Chromatography, High Pressure Liquid / Q000592:standards; D006710:Homocysteine / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D007118:Immunoassay / Q000592:standards
D006710:Homocysteine