[Common neuroimmunological features of drug addiction, alcoholism, epilepsy, and neurogenic pain syndromes].
In this review the authors analyze neuroimmune aspects of the pathogenesis of such neuropsychic diseases as drug addiction, alcoholism, epilepsy, and pathologic pain. The role of pro-inflammatory cytokines in the development of pathological pain and epilepsy is discussed. The authors analyze their own data on the role of antibodies to neuromediators, such as catecholamines, serotonin, and glutamate, in the development of various forms of neuropathology, and outline the prospects of immunotherapy of the mentioned forms of neuroimmunopathology, including immunotherapy with conjugate on homological protein carrier.
Evseev
V A
VA
Davydova
T V
TV
Vetrilé
L A
LA
Trekova
N A
NA
Fomina
V G
VG
D000437:Alcoholism / Q000276:immunology*; D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D001921:Brain / Q000276:immunology*; D016207:Cytokines / Q000276:immunology*; D004827:Epilepsy / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy; D007375:Interleukin-1 / Q000276:immunology; D015850:Interleukin-6 / Q000276:immunology; D010146:Pain / Q000276:immunology*; D059408:Pain Management; D051381:Rats; D012701:Serotonin / Q000276:immunology; D019966:Substance-Related Disorders / Q000276:immunology*
D001323:Autoantibodies; D016207:Cytokines; D007375:Interleukin-1; D015850:Interleukin-6; D012701:Serotonin