Effects of dietary diacylglycerol on the energy metabolism.
In the present study, we characterized diacylglycerol (DAG) oil in terms of energy metabolism by comparing oxygen consumption and respiratory quotient (RQ), as well as blood parameters, in rats after administration of emulsions containing either DAG or triacylglycerol (TAG) with similar fatty acid composition. Twelve male Wistar rats (250-280 g) were acclimatized, and then catheterized into the stomach, and held individually in Bollman restraining cages. After 24 hours fasting, each emulsion containing either DAG or TAG (10 g/kg body weight) was infused. Oxygen consumption and fat oxidation in the DAG group gradually increased after administration of the DAG emulsion and became significantly higher than those of the TAG group. RQ in both groups dropped after administration of emulsion, but the values of the DAG group were significantly lower than that of the TAG group. The postprandial serum triglyceride level was significantly increased from 60 minutes after administration in the TAG group, and 240 minutes in the DAG group, compared to the preprandial level. The serum triglyceride level tended to be lower in the DAG group than in the TAG group at 60 minutes and thereafter, and the statistical difference between the TAG and DAG groups was significant at 300 minutes after administration. These results suggest that DAG oil infusion might lead to higher energy expenditure and lipids oxidation compared to TAG oil with a similar fatty acid composition.
Kimura
Shuichi
S
Graduate School, Course of Human Life Science, Showa Women's University, Setagaya-ku, Tokyo, Japan.
Tsuchiya
Hitomi
H
Inage
Hiroko
H
Meguro
Shinichi
S
Matsuo
Noboru
N
Tokimitsu
Ichiro
I
D000818:Animals; D004041:Dietary Fats / Q000378:metabolism*; D004075:Diglycerides / Q000494:pharmacology*; D004655:Emulsions / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012119:Respiration; D014280:Triglycerides / Q000097:blood / Q000378:metabolism*
D004041:Dietary Fats; D004075:Diglycerides; D004655:Emulsions; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides