title: Thirteen-year follow up of isolated foveal retinoschisis in a 24-year-old woman.
abstract: Foveal retinoschisis is rarely found in women. An 11-year-old girl, from non-consanguineous parents, presented with bilateral visual loss from isolated foveal retinoschisis as confirmed by a normal fluorescein angiogram and characteristic optical coherence tomogram. Psychophysical and electrophysiological studies demonstrated mild contrast sensitivity loss, dyschromatopsia and normal full field electroretinographic responses. Visual acuity, foveal retinoschisis, electroretinography, electro-oculography and visual evoked responses remained stable after 13 years but a reduction in pattern electroretinography amplitude was noted. No mutation was found in the coding regions of the RS1 gene. Isolated foveal retinoschisis may be a form of macular dystrophy. Longer-term follow up may contribute to our understanding of this rare disease.
authors.affiliation: Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia, Australia.
authors.forename: Fred K
authors.initials: FK
authors.lastname: Chen
authors.forename: Ian L
authors.initials: IL
authors.lastname: McAllister
authors.forename: Enid S
authors.initials: ES
authors.lastname: Chelva
mesh_terms: D000328:Adult; D004585:Electrooculography; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D041441:Retinoschisis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity