title: Impaired monocyte Toll-like receptor-4 signaling in trauma and sepsis: is SIGIRR the answer?
authors.forename: Jacob E
authors.initials: JE
authors.lastname: Wang
authors.forename: Maria K
authors.initials: MK
authors.lastname: Dahle
authors.forename: Angar O
authors.initials: AO
authors.lastname: Aasen
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism*; D006801:Humans; D009000:Monocytes / Q000378:metabolism*; D053594:Myeloid Differentiation Factor 88; D012333:RNA, Messenger / Q000378:metabolism; D017472:Receptors, Interleukin-1 / Q000378:metabolism*; D018805:Sepsis / Q000378:metabolism*; D015398:Signal Transduction; D051195:Toll-Like Receptor 2 / Q000235:genetics / Q000378:metabolism; D051197:Toll-Like Receptor 4 / Q000378:metabolism; D015854:Up-Regulation
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D053594:Myeloid Differentiation Factor 88; D012333:RNA, Messenger; D017472:Receptors, Interleukin-1; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; C507779:MYD88 protein, human; C507780:Myd88 protein, mouse; C495342:TLR2 protein, human; C495345:TLR4 protein, human; C484529:SIGIRR protein, mouse