title: Model-based classification of nonstationary vocal fold vibrations.
abstract: Classification of vocal fold vibrations is an essential task of the objective assessment of voice disorders. For historical reasons, the conventional clinical examination of vocal fold vibrations is done during stationary, sustained phonation. However, the conclusions drawn from a stationary phonation are restricted to the observed steady-state vocal fold vibrations and cannot be generalized to voice mechanisms during running speech. This study addresses the approach of classifying real-time recordings of vocal fold oscillations during a nonstationary phonation paradigm in the form of a pitch raise. The classification is based on asymmetry measures derived from a time-dependent biomechanical two-mass model of the vocal folds which is adapted to observed vocal fold motion curves with an optimization procedure. After verification of the algorithm performance the method was applied to clinical problems. Recordings of ten subjects with normal voice and ten dysphonic subjects have been evaluated during stationary as well as nonstationary phonation. In the case of nonstationary phonation the model-based classification into "normal" and "dysphonic" succeeds in all cases, while it fails in the case of sustained phonation. The nonstationary vocal fold vibrations contain additional information about vocal fold irregularities, which are needed for an objective interpretation and classification of voice disorders.
authors.affiliation: Department of Phoniatrics and Pediatric Audiology, University Hospital Erlangen, Medical School, Erlangen, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Wurzbacher
authors.forename: Raphael
authors.initials: R
authors.lastname: Schwarz
authors.forename: Michael
authors.initials: M
authors.lastname: Döllinger
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hoppe
authors.forename: Ulrich
authors.initials: U
authors.lastname: Eysholdt
authors.forename: Jörg
authors.initials: J
authors.lastname: Lohscheller
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008954:Models, Biological; D010699:Phonation / Q000502:physiology*; D010897:Pitch Discrimination / Q000502:physiology; D013997:Time Factors; D014732:Vibration; D014827:Vocal Cords / Q000502:physiology*; D014832:Voice Disorders / Q000503:physiopathology*