title: Occupational peri-ocular contact dermatitis due to sensitization against black rubber components of a microscope.
abstract: A 24-year-old female working in the Department of Pathology of a University Hospital developed an acute peri-ocular eczema clearly being related to her daily work at the microscope. Patch testing revealed delayed type hypersensitivity against the black rubber mix, N-isopropyl-N'-phenyl paraphenylenediamine, N-cyclohexyl-N'-phenyl paraphenylenediamine and the rubber ring situated on the ocular of the respective microscope. This is the first report, to our knowledge, on peri-orbital allergic contact eczema because of sensitization with rubber components of a microscope.
authors.affiliation: Department of Dermatology, University Hospital Maastricht, Masstricht, the Netherlands. dku@sder.azm.nl
authors.forename: D I M
authors.initials: DI
authors.lastname: Kuijpers
authors.forename: F
authors.initials: F
authors.lastname: Hillen
authors.forename: J A
authors.initials: JA
authors.lastname: Frank
mesh_terms: D000328:Adult; D009783:Dermatitis, Occupational / Q000209:etiology*; D019557:Dermatitis, Perioral / Q000209:etiology*; D005123:Eye; D005148:Facial Dermatoses / Q000209:etiology; D005260:Female; D006801:Humans; D008853:Microscopy / Q000295:instrumentation*; D010655:Phenylenediamines / Q000009:adverse effects / Q000032:analysis; D012408:Rubber / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D010655:Phenylenediamines; D012408:Rubber; C014627:N-isopropyl-N-phenyl-4-phenylenediamine; C514096:N-cyclohexyl-N'-phenyl-p-phenylenediamine