Activation of the MMP-1 promoter by cigarette smoke in human small airway epithelial cells requires ERK MAP kinase signaling: differential response of the 1G and 2G promoter sequences.
Mercer
Becky
B
Department of Medicine, Division of Molecular Medicine, Institute of Human Nutrition, Columbia University, College of Physicians & Surgeons, New York, NY 10032, USA.
Brinckerhoff
Constance
C
D'Armiento
Jeanine
J
D004247:DNA / Q000235:genetics*; D004789:Enzyme Activation / Q000235:genetics; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism*; D015870:Gene Expression; D020022:Genetic Predisposition to Disease; D006801:Humans; D020781:Matrix Metalloproteinase 1 / Q000235:genetics* / Q000378:metabolism; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics; D029424:Pulmonary Disease, Chronic Obstructive / Q000201:enzymology / Q000235:genetics; D020545:Respiratory Mucosa / Q000201:enzymology* / Q000473:pathology; D015398:Signal Transduction / Q000235:genetics*; D012907:Smoking / Q000235:genetics* / Q000378:metabolism / Q000473:pathology
D004247:DNA; D048049:Extracellular Signal-Regulated MAP Kinases; D020781:Matrix Metalloproteinase 1