title: Modern agrochemical research: a missed opportunity for drug discovery?
abstract: The word "agrochemical" has often taken on a pejorative character in the public mind. Some of the negative tone might have coloured the perception of the industry by pharma, together with views on the chemical nature of agrochemicals that seem to be based on older pesticides that date back to the 1950s and 1960s. In this review, we try to address some of these concerns, draw out the similarities between agrochemical and pharmaceutical research and highlight opportunities for drug discovery that are offered by pesticide-related compounds, particularly with regard to herbicides and compounds with leadlike physical properties.
authors.affiliation: Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK. john.delaney@syngenta.com
authors.forename: John
authors.initials: J
authors.lastname: Delaney
authors.forename: Eric
authors.initials: E
authors.lastname: Clarke
authors.forename: David
authors.initials: D
authors.lastname: Hughes
authors.forename: Martin
authors.initials: M
authors.lastname: Rice
mesh_terms: D016573:Agrochemicals; D000818:Animals; D002622:Chemistry, Agricultural; D002626:Chemistry, Pharmaceutical; D006801:Humans; D010575:Pesticides; D004364:Pharmaceutical Preparations; D012106:Research
chemical_list: D016573:Agrochemicals; D010575:Pesticides; D004364:Pharmaceutical Preparations