title: ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis.
abstract: Negative regulation of epr in Bacillus subtilis 168 is mediated jointly by both ScoC and SinR, which bind to their respective target sites 62 bp apart. Increasing the distance between the two sites abolishes repression, indicating that the two proteins interact, thereby suggesting a mechanism of corepression.
authors.affiliation: School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
authors.forename: Prashant
authors.initials: P
authors.lastname: Kodgire
authors.forename: Madhulika
authors.initials: M
authors.lastname: Dixit
authors.forename: K Krishnamurthy
authors.initials: KK
authors.lastname: Rao
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D015536:Down-Regulation; D015964:Gene Expression Regulation, Bacterial; D010447:Peptide Hydrolases / Q000235:genetics*; D012097:Repressor Proteins / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D012097:Repressor Proteins; C442131:ScoC protein, Bacillus subtilis; D014157:Transcription Factors; C076733:FlaD protein, Bacteria; D010447:Peptide Hydrolases