Design of highly efficient receptor sites by combination of cyclodextrin units and molecular cavity in TiO2 ultrathin layer.
A highly effective approach was developed for sensitive detection of organic substances in water. In order to achieve high sensitivity and selective detection for aromatic compounds, cyclodextrin (CD) hosts and imprinting effects were combined to fabricate binding sites within TiO(2) ultrathin layer. The electrode surface was modified with ultrathin TiO(2) gel film containing a 2:1 complex of beta-CD and bisphenol A (BPA), and then the BPA moiety was removed by washing. The resulting BPA-imprinted TiO(2)/beta-CD film showed specific and sensitive detection of BPA, as confirmed by quartz crystal microbalance (QCM) and cyclic surface-polarization impedance (cSPI) measurements. The high selectivity for BPA relative to structurally related guest molecules was estimated to be 1.6-3.4 at the guest concentration of 2x10(-7)M, and was considered to arise from the synergic effect of the binding site.
Yang
Do-Hyeon
DH
Graduate School of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino, Kitakyushu 808-0135, Japan.
Ju
Myung-Jong
MJ
Maeda
Aya
A
Hayashi
Kenshi
K
Toko
Kiyoshi
K
Lee
Seung-Woo
SW
Kunitake
Toyoki
T
D001559:Benzhydryl Compounds; D001665:Binding Sites; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008839:Microelectrodes; D010636:Phenols / Q000032:analysis*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D020099:Coated Materials, Biocompatible; D003505:Cyclodextrins; D010636:Phenols; D014025:Titanium; D014874:Water Pollutants, Chemical; C009495:titanium dioxide; C006780:bisphenol A; D000098826:Bisphenol A Compounds