Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
BACKGROUND
Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne.


OBJECTIVE
To compare the effects of 30% glycolic acid peels and Jessner's solution peels on sebum secretion in facial acne patients.


METHODS
Thirty-eight patients with mild to moderate facial acne were included. Twenty-seven patients were treated with 30% glycolic acid peels and 11 patients with Jessner's solution peels. Each peel was performed twice with an interval of 2 weeks. Before and 2 weeks after each peel, sebum levels of forehead, nose, chin and cheeks were measured by using a Sebumeter (SM810 Courage & Khazaka, Cologne, Germany).


RESULTS
The sebum levels were not significantly changed by two peels treatments of 30% glycolic acid peels or Jessner's solution peels on the facial skins of patients with facial acne.


CONCLUSIONS
The two types of peels, 30% glycolic acid peels and Jessner's solution peels, did not affect sebum secretion of the facial skins of patients with facial acne after the two peels treatments. The accumulative effects of more than two peels treatments using these modalities need further evaluation.
Lee
S H
SH
Department of Dermatology, Seoul National University College of Medicine, and Seoul National University Bundang Hospital, Korea.
Huh
C H
CH
Park
K C
KC
Youn
S W
SW
D000152:Acne Vulgaris / Q000503:physiopathology* / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D002615:Chemexfoliation / Q000379:methods; D004338:Drug Combinations; D000431:Ethanol / Q000008:administration & dosage; D005148:Facial Dermatoses / Q000503:physiopathology* / Q000628:therapy*; D005260:Female; D006016:Glycolates / Q000008:administration & dosage; D006801:Humans; D019344:Lactic Acid / Q000008:administration & dosage; D008297:Male; D012118:Resorcinols / Q000008:administration & dosage; D012459:Salicylates / Q000008:administration & dosage; D012629:Sebum / Q000378:metabolism*
D004338:Drug Combinations; D006016:Glycolates; C061170:Jessner's solution; D012118:Resorcinols; D012459:Salicylates; C031149:glycolic acid; D019344:Lactic Acid; D000431:Ethanol