Outbreak of colonization and infection with vancomycin-resistant Enterococcus faecium in a French university hospital.
An outbreak of infection with vancomycin-resistant Enterococcus faecium occurred at Hotel-Dieu Hospital (Clermont-Ferrand, France). A case-control study was performed in the infectious diseases and hematology units of the hospital. Urinary catheter use (odds ratio [OR], 12 [95% confidence interval {CI}, 1.5-90]; P<.02), prior exposure to a third-generation cephalosporin (OR, 22 [95% CI, 3-152]; P=.002), and prior exposure to antianaerobials (OR, 11 [95% CI, 1.5-88]; P<.02) were independently predictive of vancomycin-resistant Enterococcus faecium carriage.
Lesens
Olivier
O
Service des Maladies Infectieuses et Tropicales, Clermont-Ferrand, France. olesens@chu-clermontferrand.fr
Mihaila
L
L
Robin
F
F
Baud
O
O
Romaszko
J P
JP
Tourniac
O
O
Constantin
J M
JM
Souweine
B
B
Bonnet
R
R
Bouvet
A
A
Beytout
J
J
Traore
O
O
Laurichesse
H
H
D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D016984:Enterococcus faecium / Q000302:isolation & purification / Q000472:pathogenicity*; D005260:Female; D005602:France / Q000453:epidemiology; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology*; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D020713:Vancomycin Resistance