title: New acylated triterpene saponins from Polygala tenuifolia willd.
abstract: Two new acylated presenegenin glycosides E-onjisaponin H (5) and Z-onjisaponin (6) together with seven known saponins were isolated from the roots of Polygala tenuifolia Willd. Compounds 5 and 6 were obtained as a pair of isomers due to trans and cis-p-methoxycinnamoyl. Their structures were elucidated mainly by 2D-NMR techniques including 1H-1HCOSY, TOCSY, HSQC, HMBC as 3-O-(beta-D-glucopyranosyl) presenegenin 28-[O-beta-D-apiofuranosyl-(1 --> 3)-O-[beta-D-xylopyranosyl-(1 --> 4)]-O-alpha-L-rhamnopyranosyl-(1 --> 2)-O-[alpha-L-rhamnopyranosyl-(1 --> 3)]-4-O-[(E)-p-methoxycinnamoyl]-beta-D-fucopyranosyl] ester (5) and its (Z)-isomer (6).
authors.affiliation: Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, China.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Jiang
authors.forename: P-F
authors.initials: PF
authors.lastname: Tu
mesh_terms: D000215:Acylation; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D031801:Polygala / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: C514646:E-onjisaponin H; D012503:Saponins; D014315:Triterpenes; C514645:Z-onjisaponin