title: Effect of prior exposure to hand-transmitted vibration on cold response of digital arteries.
abstract: OBJECTIVE
  To investigate whether prior exposure to hand-transmitted vibration on the day of a cold provocation test affects the cold response of digital arteries.
  
  
  METHODS
  Each of ten healthy men attended two experimental sessions in which their right hands were exposed for 60 min to either contact force alone (5 N) or a combination of contact force (5 N) and 125-Hz vertical vibration with an acceleration magnitude of 64 m s(-2) r.m.s. (unweighted). Finger systolic blood pressure (FSBP) during local cooling to 10 degrees C was measured in the second right finger (exposed hand) and the second left finger (unexposed hand) before exposure and at 30 and 70 min after the end of both exposure conditions.
  
  
  RESULTS
  Analysis of repeated measures of FSBP during local cooling by means of an autoregressive model revealed no significant difference in cold-induced vasoconstriction of the digital arteries between exposure to contact force alone and combined exposure to contact force and vibration. There were no significant changes in the cold response of digital arteries over time in either the right or the left hand after exposure of the right hand to either the contact force alone or the combined contact force and vibration.
  
  
  CONCLUSIONS
  The results of this experimental study of the influence of prior vibration exposure on the cold test results suggest that in healthy men recent exposure to contact force and moderate levels of hand-transmitted vibration does not affect the response of finger circulation to cold provocation. These findings may be of practical importance for the definition of test conditions in the field, especially the length of time required between the last occupational exposure to tool vibration and the commencement of objective vascular testing.
authors.affiliation: Unità Clinica Operativa di Medicina del Lavoro, Dipartimento di Scienze di Medicina Pubblica, Università degli Studi di Trieste, Centro Tumori, Via della Pietà, 19, 34129 Trieste, Italy. bovenzi@units.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Bovenzi
authors.forename: Alexandra J L
authors.initials: AJ
authors.lastname: Welsh
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Griffin
mesh_terms: D001158:Arteries / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology*; D003080:Cold Temperature / Q000009:adverse effects*; D004781:Environmental Exposure / Q000009:adverse effects*; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D008297:Male; D012039:Regional Blood Flow / Q000502:physiology; D014732:Vibration / Q000009:adverse effects*