title: Case studies: Use of salicylic acid (Avosil) and hydrogel (Avogel) in limiting scar formation.
abstract: OBJECTIVE
  The purpose of this report is to present the results of a preliminary treatment regimen for hypertrophic scars combining topical 2% salicylic acid cream (Avosil) with an overlay of hydrogel dressing (Avogel).
  
  
  METHODS
  The study group consisted of 3 patients with symptomatic hypertrophic scars: 2 presternal and 1 on the inner thigh. Scars were divided into 3 equal-size areas: (1) untreated control, (2) hydrogel alone, and (3) 2% salicylic acid with hydrogel cover. Treatments were applied every 8 to 12 hours and a Velcro appliance was employed to cover the area during treatment. The total length of treatment was 60 days.
  
  
  RESULTS
  At the end of the 60-day treatment protocol, the area treated with 2% salicylic acid and hydrogel was asymptomatic. In contrast, the hydrogel-treated and untreated control areas remained erythematous and symptomatic for burning pain and pruritus.
  
  
  CONCLUSIONS
  This small study suggests the efficacy of combined salicylic acid and hydrogel therapy in the treatment of hypertrophic scars. More extensive studies of scar treatment with salicylic acid and hydrogel are needed. These studies must be larger in scope to carefully document the spectrum of patient responses and should include methods for evaluating alterations in the levels of different inflammatory mediators.
authors.affiliation: St. Mary's Hospital, Hobart, IN, USA. drjohnrdanielson@yahoo.com
authors.forename: John R
authors.initials: JR
authors.lastname: Danielson
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Walter