Improved method for the determination of zinc pyrithione in environmental water samples incorporating on-line extraction and preconcentration coupled with liquid chromatography atmospheric pressure chemical ionisation mass spectrometry.
A method has been developed for the determination of zinc pyrithione (ZnPT) in environmental water samples using monolithic reversed-phase silica columns for rapid on-line large volume solid phase extraction in tandem with on-line matrix removal using sacrificial strong anion exchange (SAX) columns. This is coupled with reversed-phase liquid chromatography with atmospheric pressure chemical ionisation mass spectrometric detection. Limits of detection in spiked river water samples, using a 200 mL preconcentration volume, were determined as 18 ng L(-1), with a limit of quantitation of 62 ng L(-1). The percentage recovery from spiked river water was found to be 72+/-9 (n=3 extractions), whilst overall method precision, following 10 repeat complete analyses was found to be 27% RSD at 1 microg L(-1). Linearity was determined over the concentration range of 0.25-10 microg L(-1) and the calculated regression coefficient was R(2)=0.9802. The method was used to investigate the environmental fate of zinc pyrithione in waters and its partition coefficient between sediment and water phases.
Bones
Jonathan
J
National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.
Thomas
Kevin V
KV
Paull
Brett
B
D001274:Atmospheric Pressure; D002853:Chromatography, Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000032:analysis* / Q000737:chemistry; D011725:Pyridines / Q000032:analysis* / Q000737:chemistry; D015203:Reproducibility of Results; D014867:Water / Q000032:analysis* / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000737:chemistry
D009942:Organometallic Compounds; D011725:Pyridines; D014874:Water Pollutants, Chemical; D014867:Water; C010423:pyrithione zinc