Expression of the trxC gene of Rhodobacter capsulatus: response to cellular redox status is mediated by the transcriptional regulator OxyR.
Despite the importance of thioredoxins in cellular functions, little is known about the regulation of trx genes. To understand the molecular mechanisms involved in the regulation of the Rhodobacter capsulatus trxC gene, the expression of this gene was investigated. We describe OxyR-dependent redox regulation of the trxC gene that adjusts the levels of thioredoxins in the cell.
Zeller
Tanja
T
Institut für Mikrobiologie und Molekularbiologie, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.
Li
Kuanyu
K
Klug
Gabriele
G
D000222:Adaptation, Physiological; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D017930:Genes, Reporter; D008969:Molecular Sequence Data; D016877:Oxidants / Q000494:pharmacology; D010084:Oxidation-Reduction; D011401:Promoter Regions, Genetic; D016354:Rhodobacter capsulatus / Q000235:genetics* / Q000378:metabolism*; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D013879:Thioredoxins / Q000096:biosynthesis*; D001616:beta-Galactosidase / Q000032:analysis / Q000235:genetics
D004268:DNA-Binding Proteins; D016877:Oxidants; D013439:Sulfhydryl Reagents; D013879:Thioredoxins; D001616:beta-Galactosidase