Paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma.
Epidermolysis bullosa acquisita is a rare acquired autoimmune subepidermal blistering disease that clinically resembles other vesiculobullous lesions such as pemphigus vulgaris and cicatricial pemphigoid. Multiple myeloma is the most common plasma cell malignant disorder characterized by a single clonal expansion and increased level of a single immunoglobulin. Epidermolysis bullosa acquisita has been reported with other systemic diseases such as lymphoma. In this case report, we present a patient with paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma.
Radfar
Lida
L
Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, USA. lradfar@buffalo.edu
Fatahzadeh
Mahnaz
M
Shahamat
Yasaman
Y
Sirois
David
D
D000368:Aged; D001485:Basement Membrane / Q000276:immunology; D003176:Complement C3 / Q000032:analysis; D016107:Epidermolysis Bullosa Acquisita / Q000209:etiology* / Q000276:immunology; D019085:Fluorescent Antibody Technique, Direct; D005891:Gingivitis / Q000209:etiology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D009101:Multiple Myeloma / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000276:immunology
D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G