Fulminant septicaemia caused by multi-drug-resistant Streptococcus mitis following unrelated cord blood transplantation.
Streptococcus mitis (a common and usually harmless bacterium found in the nose, mouth and throat) can have an unusually high level of resistance to beta-lactam antibiotics. We report a patient who developed fatal Streptococcus mitis septicaemia following unrelated cord blood transplantation. Administration of vancomycin to patients with recurrent fever during allogeneic stem cell transplantation might be indicated.
Chen
Shih-Hsiang
SH
Division of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Taiwan, Republic of China.
Yang
Chao-Ping
CP
Chiu
Cheng-Hsun
CH
Chia
Ju-Hsin
JH
Huang
I-Anne
IA
Jaing
Tang-Her
TH
D002648:Child; D024901:Drug Resistance, Multiple, Bacterial; D017809:Fatal Outcome; D005260:Female; D005312:Fetal Blood / Q000637:transplantation*; D006801:Humans; D018805:Sepsis / Q000209:etiology* / Q000382:microbiology; D013290:Streptococcal Infections / Q000209:etiology* / Q000382:microbiology; D034361:Streptococcus mitis / Q000187:drug effects* / Q000302:isolation & purification; D065227:Transfusion Reaction; D017086:beta-Thalassemia / Q000628:therapy