Primary Epstein-Barr virus infection with pneumonia transmitted by allogeneic bone marrow after transplantation.
We report a case of primary Epstein-Barr virus infection with lung involvement occurring 1 month after bone marrow transplantation. The transplant recipient had serological test results that were negative for Epstein-Barr virus before transplantation. The virus must have been transmitted by the donor's bone marrow, which was positive for Epstein-Barr virus. The patient recovered after rituximab and corticosteroid therapy.
Teira
Pierre
P
Service d'Hématologie-Allogreffe, Hôpital Saint Louis, Assistance Publique Hôpitaux de Paris, Paris, France.
Agbalika
Felix
F
Bergeron
Anne
A
Bernaudin
Françoise
F
Carmagnat
Maryvonnick
M
Peffault de Latour
Régis
R
Rocha
Vanderson
V
Devergie
Agnès
A
Rabian
Claire
C
Gluckman
Eliane
E
Ribaud
Patricia
P
Socié
Gérard
G
Robin
Marie
M
D001853:Bone Marrow; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D020031:Epstein-Barr Virus Infections / Q000209:etiology*; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D009894:Opportunistic Infections / Q000209:etiology; D011014:Pneumonia / Q000209:etiology*; D014184:Transplantation, Homologous / Q000009:adverse effects*