title: [IOP diurnal fluctuations in patients presenting pseudoexfoliative syndrome].
abstract: OBJECTIVE
  To analyze the IOP diurnal fluctuations in patients presenting pseudoexfoliative syndrome (PEX) compared to those without PEX.
  
  
  METHODS
  A clinical observational prospective study, one year, on 2 groups of patients: group A (13 patients)--with pseudoexfoliative syndrome (PEX) and group B, control, (11 patients)--without PEX. The groups were homogeneous about the age and sex distribution. At each visit 4 IOP measurements were taken using Goldmann aplanotonometry.
  
  
  RESULTS
  In PEX patients the IOP had greater values during the study period compared to the control group. By comparing the two groups have been observed significant differences about the maximum IOP, the mean IOP and the diurnal fluctuations, also about the incidence of the complications.
  
  
  CONCLUSIONS
  The IOP diurnal fluctuations in PEX patients are significantly greater than the physiological ones and therefore influence the therapeutic attitude and the prognostic. The significant fluctuations in the IOP diurnal curve are an important predictive factor for the eyes that will develop secondary glaucoma. The pseudoexfoliative syndrome is an independent risk factor for glaucoma in patients with intraocular hypertension.
authors.affiliation: Clinica de Oftalmologie - Spitalul Clinic de Urgenta Militar Central, Sef de Clinica, Bucuresti.
authors.forename: A
authors.initials: A
authors.lastname: Nenciu
authors.forename: C
authors.initials: C
authors.lastname: Stefan
authors.forename: Diana
authors.initials: D
authors.lastname: Melinte
authors.forename: Cristina
authors.initials: C
authors.lastname: Malcea
authors.forename: Eliza
authors.initials: E
authors.lastname: Tebeanu
authors.forename: Irina
authors.initials: I
authors.lastname: Nae
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002940:Circadian Rhythm; D017889:Exfoliation Syndrome / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D011446:Prospective Studies; D014065:Tonometry, Ocular