Cataract surgery practice and endophthalmitis prevention by Australian and New Zealand ophthalmologists.
OBJECTIVE
Our aim was to examine current cataract surgery practice and the methods of chemoprophylaxis used in Australia and New Zealand, and to determine if these factors were related to self-reported incidence rates of postoperative endophthalmitis.


METHODS
All Fellows and trainees of the Royal Australian and New Zealand College of Ophthalmologists were surveyed about their cataract surgery practices and methods of chemoprophylaxis for the prevention of postoperative endophthalmitis. Associations between self-reported incidence rates of endophthalmitis and clinical practice were examined using multivariate Poisson regression modelling.


RESULTS
There were 731 respondents (81.6% of 896 surveyed) to the survey. Respondents reported a total of 162,120 cataract operations and 92 cases of endophthalmitis in 2003, a cumulative incidence of 0.057%. The self-reported incidence of endophthalmitis varied from 0.034% in Victoria to 0.56% in the Northern Territory. Topical antibiotics were used preoperatively by 46.7% compared with 97.4% postoperatively; while only 44.1% used subconjunctival antibiotics. The routine use of subconjunctival antibiotic halved the self-reported incidence of postoperative endophthalmitis (incidence rate ratio 0.53, 95% confidence interval 0.30-0.92).


CONCLUSIONS
Subconjunctival antibiotics may be beneficial in the prevention of endophthalmitis after cataract surgery.
Rosha
Deepinder S
DS
School of Pharmacy, Curtin University of Technology, Bentley, and Department of Ophthalmology, Royal Perth Hospital, Western Australia, Australia.
Ng
Jonathon Q
JQ
Morlet
Nigel
N
Boekelaar
Michelle
M
Wilson
Shea
S
Hendrie
Delia
D
Semmens
James B
JB
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001315:Australia / Q000453:epidemiology; D002387:Cataract Extraction / Q000009:adverse effects / Q000706:statistics & numerical data*; D009877:Endophthalmitis / Q000453:epidemiology / Q000517:prevention & control*; D015818:Eye Infections, Bacterial / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009520:New Zealand / Q000453:epidemiology; D009885:Ophthalmology / Q000706:statistics & numerical data*; D011183:Postoperative Complications; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D012307:Risk Factors; D011795:Surveys and Questionnaires
D000900:Anti-Bacterial Agents