Granular acute lymphoblastic leukemia in adults: report of a case and review of the literature.
The diagnosis of granular acute lymphoblastic leukemia (ALL) can be problematic as the cytoplasmic granules found in many blast cells may mimic those seen in acute myelogenous leukemia (AML). This rare variant of B-cell ALL is more commonly diagnosed in children, but may occur in adults. We report a case of granular B-ALL in a 56-year-old female and review the literature.
Fulcher
James W
JW
Department of Pathology and Laboratory Medicine, Medical College of Georgia, Augusta, GA 30912, USA. jfulcher@mcg.edu
Allred
Thomas J
TJ
Kulharya
Anita
A
Satya-Prakash
K L
KL
Seigler
Maree
M
Neibarger
Doris
D
Mazzella
Fermina M
FM
D001706:Biopsy; D001854:Bone Marrow Cells / Q000473:pathology*; D003594:Cytoplasmic Granules / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*