Current and future options for the treatment of chemotherapy-induced anaemia.
Chemotherapy-induced anaemia (CIA) is a significant source of morbidity in patients receiving treatment for cancer. There are three products currently available for the treatment of CIA: epoetin alfa, epoetin beta and darbepoetin alfa. Several organisations have published recommendations for the use of these agents. Several randomised, controlled trials have been conducted comparing the most popular dosing regimens of epoetin alfa and darbepoetin alfa, with conflicting results. Information regarding survival and adverse event data related to these agents continues to create debate. This review considers four new agents that are under development for the treatment of CIA.
Ziegler
Jennifer A
JA
Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
Herrington
Jon D
JD
D000740:Anemia / Q000139:chemically induced* / Q000188:drug therapy* / Q000473:pathology; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004920:Erythropoiesis / Q000187:drug effects; D006801:Humans; D017410:Practice Guidelines as Topic; D015996:Survival Rate
D000970:Antineoplastic Agents