title: Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism.
abstract: During conditions with experimental diabetes mellitus, it is evident that several alterations in renal oxygen metabolism occur, including increased mitochondrial respiration and increased lactate accumulation in the renal tissue. Consequently, these alterations will contribute to decrease the interstitial pO2, preferentially in the renal medulla of animals with sustained long-term hyperglycemia.
authors.affiliation: Department of Medical Cell Biology, Uppsala University, Biomedical Center, box 571, SE 751 23 Uppsala, Sweden.
authors.forename: Fredrik
authors.initials: F
authors.lastname: Palm
authors.forename: Per-Ola
authors.initials: PO
authors.lastname: Carlsson
authors.forename: Angelica
authors.initials: A
authors.lastname: Fasching
authors.forename: Peter
authors.initials: P
authors.lastname: Hansell
authors.forename: Per
authors.initials: P
authors.lastname: Liss
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000378:metabolism* / Q000503:physiopathology*; D006801:Humans; D007668:Kidney / Q000378:metabolism* / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology