Synthesis and stereochemical confirmation of the secoiridoid glucosides nudiflosides D and A.
We describe herein an efficient access to the highly substituted cyclopentane unit present in the Nudifloside secoiridoid family via crotyl phosphonamide anion mediated conjugate addition to cyclopentenone.
Hanessian
Stephen
S
Department of Chemistry, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montréal, Québec H3C 3J7 Canada. stephen.hanessian@umontreal.ca
Mainetti
Emily
E
Lecomte
Fabien
F
D039823:Iridoids / Q000138:chemical synthesis*; D015394:Molecular Structure
D039823:Iridoids; C520909:nudifloside A; C520908:nudifloside D