Huntington disease as a dual diagnosis disorder: data from the National Research Roster for Huntington disease patients and families.
Although an extensive literature characterizes a linkage between primary mental illnesses and substance use disorders, a paucity of research exists concerning dual diagnosis phenomena in Huntington disease (HD). Data from the National Research Roster on HD suggest that higher levels of alcohol and cigarette use are associated with greater ratings of psychiatric symptoms and a younger age of HD symptom onset, and that progressive alcohol use after HD symptom onset is linked with worsening psychiatric symptom progression. These findings suggest HD entails dual diagnosis phenomena similar to that identified in patients with primary psychiatric disorders.
Ehret
Jason C
JC
Department of Psychiatry, Indiana University School of Medicine, IPR, 791 Union Drive, Indinapolis, IN 46202, United States.
Day
Patricia S
PS
Wiegand
Ryan
R
Wojcieszek
Joanne
J
Chambers
R Andrew
RA
D000369:Aged, 80 and over; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000453:epidemiology*; D008297:Male; D009313:National Health Programs; D012042:Registries; D019966:Substance-Related Disorders / Q000453:epidemiology*; D014481:United States