A case report of oxidative stress in a patient with anorexia nervosa.
OBJECTIVE
Liver injury is well known as a complication of anorexia nervosa (AN), and steatosis of the liver has been thought to be the main cause of the injury. However, the precise mechanism for the liver injury is still unclear.


RESULTS
We had a chance to examine the histological change of the liver with AN, and found that not only fat deposit but also peroxidated lipid products and irons were recognized in hepatocytes.


CONCLUSIONS
Our present case demonstrates that oxidative stresses in hepatocytes, which might be associated with iron deposition, could be involved in the pathogenesis of liver injury in patients with AN.
Tajiri
Kazuto
K
Third Department of Internal Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan.
Shimizu
Yukihiro
Y
Tsuneyama
Koichi
K
Sugiyama
Toshiro
T
D000328:Adult; D000856:Anorexia Nervosa / Q000503:physiopathology*; D005234:Fatty Liver / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D006486:Hemosiderosis / Q000150:complications; D006801:Humans; D044342:Malnutrition / Q000150:complications; D018384:Oxidative Stress / Q000502:physiology*; D014057:Tomography, X-Ray Computed