New surprises in genetic coding and how an ingenious experiment was almost scooped, by evolution.
In 1962, one of the most creative and cogent experiments on the protein coding problem was published. Now it has been discovered that archaebacteria had been doing a related kind of "experiment" all along. Both involve a trick: changing an amino acid that is already attached to a "correct" transfer RNA.
Pederson
Thoru
T
Department of Biochemistry and Molecular Pharmacology, Program in Cell Dynamics, University of Massachusetts Medical School, 377 Plantation St., Worcester, MA 01605, USA. thoru.pederson@umassmed.edu
D001105:Archaea / Q000235:genetics; D019143:Evolution, Molecular; D005815:Genetic Code; D019642:RNA, Archaeal / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D012345:RNA, Transfer, Amino Acid-Specific / Q000235:genetics
D019642:RNA, Archaeal; D012345:RNA, Transfer, Amino Acid-Specific; D012343:RNA, Transfer