title: [Motor neuron disease and ubiquitin-proteasome system dysfunction].
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Niwa
authors.forename: Gen
authors.initials: G
authors.lastname: Sobue
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000209:etiology / Q000473:pathology; D000818:Animals; D006801:Humans; D045586:Intranuclear Inclusion Bodies / Q000378:metabolism / Q000473:pathology; D016472:Motor Neuron Disease / Q000209:etiology*; D009046:Motor Neurons / Q000473:pathology; D017354:Point Mutation; D046988:Proteasome Endopeptidase Complex / Q000502:physiology*; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D000072105:Superoxide Dismutase-1; D025801:Ubiquitin / Q000378:metabolism / Q000502:physiology*; D044767:Ubiquitin-Protein Ligases / Q000502:physiology
chemical_list: C000606290:SOD1 protein, human; D025801:Ubiquitin; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1; D044767:Ubiquitin-Protein Ligases; D046988:Proteasome Endopeptidase Complex