title: Treatment results of pathological fractures of the long bones: a retrospective analysis of 88 patients.
abstract: Due to the advances in oncological therapy, the life expectancy of patients with malignant tumours and the incidence of pathological fractures have increased over the last decades. Pathological fractures of the long bones are common complications of metastatic disease; however, the outcome of different surgical techniques for the treatment of these fractures has not been clearly defined. The aim of this study was to evaluate differences in patient's survival and postoperative complications after the treatment of pathological fractures of the long bones. Eighty-eight patients with 96 pathological fractures of the long bones were analysed retrospectively. Seventy-five patients with 83 fractures received surgical treatment. The operative treatments used were intramedullary fixation, gliding screws, plate osteosynthesis or arthroplasty. Five patients were still alive at the end of data collection at a median time of 42.5 months, and 16.2% survived 1 year, 7% 2 years and 4% more than 3 years postoperatively. All surgically treated patients had a reduction of local pain and were able to walk after the operation. The overall rate of complications was 8%. Early palliative treatment of pathological fractures of the long bones is indicated in most patients in the advanced stage of metastatic disease. The low complication rate, reduction of local pain and early mobilisation justify the surgical stabilisation of fractures in this cohort of patients.
authors.affiliation: Department of Traumatology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria. kambiz.sarahrudi@meduniwien.ac.at
authors.forename: Kambiz
authors.initials: K
authors.lastname: Sarahrudi
authors.forename: Katherina
authors.initials: K
authors.lastname: Hora
authors.forename: Thomas
authors.initials: T
authors.lastname: Heinz
authors.forename: Steven
authors.initials: S
authors.lastname: Millington
authors.forename: Vilmos
authors.initials: V
authors.lastname: Vécsei
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D050280:Arm Bones / Q000293:injuries*; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary*; D005260:Female; D005592:Fracture Fixation / Q000009:adverse effects / Q000379:methods*; D005598:Fractures, Spontaneous / Q000601:surgery*; D006801:Humans; D007867:Leg Bones / Q000293:injuries*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D012189:Retrospective Studies; D016019:Survival Analysis