title: Corrosive injury to upper gastrointestinal tract: Still a major surgical dilemma.
abstract: In the developed and developing countries, corrosive injury to the gastrointestinal system as a consequence of either accidental ingestion or as a result of self-harm has become a less common phenomenon compared to decades ago. This could partly be attributed to the tighter legislation imposed by the government in these countries on detergents and other corrosive products and general public awareness. Most busy upper gastrointestinal surgical units in these countries, especially in the developed countries will only encounter a small number of cases per year. Up to date knowledge on the best management approach is lacking. In this article, we present our experience of two contrasting cases of corrosive injury to the upper gastrointestinal tract in our thoracic unit in the last 2 years and an up-to-date Medline literature search has been carried out to highlight the areas of controversies in the management of corrosive injuries of the upper gastrointestinal tract. We concluded that the main principle in managing such patients requires a good understanding of the pathophysiology of corrosive injury in order to plan both acute and future management. Each patient must be evaluated individually as the clinical picture varies widely. Signs and symptoms alone are an unreliable guide to injury.
authors.affiliation: The Royal National Nose, Throat and Ear Hospital, London, WC1X 8DA, United Kingdom. lsm_keh@hotmail.com
authors.forename: Siew Min
authors.initials: SM
authors.lastname: Keh
authors.forename: Nzewi
authors.initials: N
authors.lastname: Onyekwelu
authors.forename: Kieran
authors.initials: K
authors.lastname: McManus
authors.forename: Jim
authors.initials: J
authors.lastname: McGuigan
mesh_terms: D000328:Adult; D002057:Burns, Chemical / Q000175:diagnosis* / Q000628:therapy; D002277:Carcinoma / Q000139:chemically induced; D002424:Caustics / Q000633:toxicity*; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000139:chemically induced; D004947:Esophagus / Q000187:drug effects*; D006801:Humans; D008297:Male; D013256:Steroids / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000139:chemically induced; D041742:Upper Gastrointestinal Tract / Q000187:drug effects* / Q000293:injuries* / Q000601:surgery*
chemical_list: D002424:Caustics; D013256:Steroids