Squamous cell carcinoma of the rectum in ulcerative colitis: case report and review of the literature.
The majority of colorectal carcinomas diagnosed are adenocarcinomas. Squamous cell carcinomas (SCC) of the rectum are rare tumors, and were reported as rare complication of inflammatory bowel disease. Surgery is the most effective therapy; and adjuvant chemotherapy and radiotherapy should also be considered. We report two cases of ulcerative colitis-associated SCC of the rectum. The lesions were treated with chemoradiotherapy with complete response.
Pikarsky
Alon J
AJ
Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA.
Belin
Bruce
B
Efron
Jonathan
J
Woodhouse
Sherry
S
Weiss
Eric G
EG
Wexner
Steven D
SD
Nogueras
Juan J
JJ
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011878:Radiotherapy; D012004:Rectal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D012074:Remission Induction / Q000379:methods
D000970:Antineoplastic Agents