title: Superior longitudinal fasciculus subserves vestibular network in humans.
abstract: Vestibular function is known to be represented in a large-scale network within the brain. Although much is known about the topography of this cortical network, the subcortical anatomo-functional connectivity has received less attention. We present three patients operated on while conscious for cerebral low-grade gliomas, in which we elicited vestibular symptoms during subcortical stimulation. Anatomo-functional correlations between postoperative imaging and intraoperative findings suggest the involvement of the superior longitudinal fasciculus in the spreading of the vestibular symptoms. We argue that this fasciculus plays a major role in the functional connectivity of the areas involved in the complex multimodal network that controls vestibular function.
authors.affiliation: Department of Neurosurgery, University of Genova, San Martino Hospital, San Martino, Genova, Italy.
authors.forename: Giannantonio
authors.initials: G
authors.lastname: Spena
authors.forename: Peggy
authors.initials: P
authors.lastname: Gatignol
authors.forename: Laurent
authors.initials: L
authors.lastname: Capelle
authors.forename: Hugues
authors.initials: H
authors.lastname: Duffau
mesh_terms: D001306:Auditory Pathways / Q000473:pathology / Q000503:physiopathology*; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000473:pathology* / Q000503:physiopathology*; D005910:Glioma / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D013687:Telencephalon / Q000473:pathology*; D014724:Vestibular Function Tests / Q000379:methods