title: The enantioselective step in the nickel-catalyzed hydrocyanation of 1,3-cyclohexadiene.
abstract: On the basis of deuterium labeling experiments and an equal 1,2-/1,4-product distribution, the reductive elimination of the product has been established to be the enantioselective step in the nickel-catalyzed hydrocyanation of 1,3-cyclohexadiene. This could be achieved by successfully exploiting the rather unique features of this reaction: identical product formation for 1,2- and 1,4-addition, cis addition over the diene, and high enantiomeric excess.
authors.affiliation: Laboratory of Homogeneous Catalysis, Eindhoven University of Technology, Eindhoven, The Netherlands.
authors.forename: Jos
authors.initials: J
authors.lastname: Wilting
authors.forename: Michèle
authors.initials: M
authors.lastname: Janssen
authors.forename: Christian
authors.initials: C
authors.lastname: Müller
authors.forename: Dieter
authors.initials: D
authors.lastname: Vogt