title: [Setup a model for study the interfere between chemokine and immunocyte].
abstract: OBJECTIVE
  To investigated the effect of chemoattractant of rhTNF-alpha on TB-LCL. Set up a model for study the interaction between cytokine and B cells.
  
  
  METHODS
  PTC were transfected with Epstein Barr virus, to get tonsil B lymphoblastic cell line(TB-LCL).
  
  
  RESULTS
  It was found rhTNF-alpha can chemotactic TB-LCL, in a dose-dependent manner and this chemotactic effect can be blocked by the neutralizing antibody E6 against TNF.
  
  
  CONCLUSIONS
  This is an useful model in study the interfere between chemokine and immunocyte.
authors.affiliation: Department of Otolaryngology, No. 117 Hospital of PLA, Hangzhou 310004, China. meek@263.net
authors.forename: Mike
authors.initials: M
authors.lastname: Min
authors.forename: Chaowu
authors.initials: C
authors.lastname: Ma
authors.forename: Yuqin
authors.initials: Y
authors.lastname: Zhan
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Xu
authors.forename: Hao
authors.initials: H
authors.lastname: Sun
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology* / Q000821:virology; D002461:Cell Line, Transformed; D002633:Chemotaxis; D006801:Humans; D014066:Palatine Tonsil / Q000276:immunology*; D011994:Recombinant Proteins / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
chemical_list: D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha