Arthropathy and cutaneous manifestations in a 28-year-old patient with cystic fibrosis.
We report on a 28-year-old man with known cystic fibrosis who presented with pain and cutaneous nodules in the elbow joints. His symptoms had appeared episodically in the previous months, they were always self-limiting, and independent of pulmonary exacerbations. A radiograph of the joints was unremarkable. These findings fit well with a special form of CF-related arthritis. As in the case of classical CF arthritis, the treatment to be considered is, in particular, symptomatic administration of non-steroidal anti-inflammatory drugs and possibly glucocorticoids. Also under discussion as a further possibility is the use of antibiotics. Our patient has always refused medication. The condition again proved to be self-limiting. In contrast to the classical form of CF arthritis, the special form is not associated with either joint swelling or local warmth. In the presence of arthritic symptoms in CF patients, consideration must always be given to a hypertrophic pulmonary osteoarthropathy. The latter, however, shows typical radiological changes and is exacerbated by lung infections. The presence of arthritic pathologies in a patient with CF further underscores the fact that CF is a multiorgan morbid condition.
Lampert
S
S
Medical Department 1, University of Erlangen-Nuremberg, Ulmenweg 18, D- 91054 Erlangen, Germany. Sabine.Lampert@med1.imed.uni-erlangen.de
Schahin
S Pour
SP
Wiest
G H
GH
Hahn
E G
EG
Ficker
J H
JH
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003550:Cystic Fibrosis / Q000150:complications* / Q000473:pathology; D004551:Elbow Joint; D006801:Humans; D007592:Joint Diseases / Q000150:complications* / Q000473:pathology; D008297:Male; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D010146:Pain; D012867:Skin / Q000473:pathology*