title: Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients.
abstract: OBJECTIVE
  To analyze the relationship between visceral obesity and urinary albumin excretion rate (UAER).
  
  
  METHODS
  A cross-sectional study of 73 normoalbuminuric (urinary albumin excretion rate < 20 microg/min) type 2 patients was performed. Patients were divided into two groups according to the median of UAER (7.5 microg/min). Office auscultatory blood pressure was measured in sitting position after a 10-min rest.
  
  
  RESULTS
  Waist to hip ratio was higher in the group with UAER > 7.0 microg/min (0.98 +/- 0.08), when compared to the other group (0.93 +/- 0.08, p= 0.01). Waist to hip ratio significantly correlated with UAER (r = 0.28; p= 0.018). In multiple linear regression analysis, only waist to hip ratio was associated with UAER (r = 0.29; p = 0.04). A1c, DM duration and systolic BP levels were excluded from the model.
  
  
  CONCLUSIONS
  Type 2 normoalbuminuric diabetic patients with higher levels of UAER could represent a group with an elevated risk for the development of cardiovascular diseases.
authors.affiliation: Endocrinology Division, Hospital Independência, Universidade Luterana do Brasil, Av. Taquara 386/401, 90460-210 Porto Alegre, RS. mpecis@terra.com.br
authors.forename: Miriam
authors.initials: M
authors.lastname: Pecis
authors.forename: Lérida M A
authors.initials: LM
authors.lastname: Zaslavsky
authors.forename: Fabrício B
authors.initials: FB
authors.lastname: Mallmann
authors.forename: Larissa
authors.initials: L
authors.lastname: Pante
authors.forename: Ana L D
authors.initials: AL
authors.lastname: Krahe
authors.forename: Fernanda F
authors.initials: FF
authors.lastname: Stringhari
authors.forename: Luis H
authors.initials: LH
authors.lastname: Canani
mesh_terms: D000418:Albumins / Q000378:metabolism*; D000419:Albuminuria / Q000652:urine*; D002318:Cardiovascular Diseases / Q000209:etiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000209:etiology; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat; D008297:Male; D009765:Obesity / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D018709:Statistics, Nonparametric; D049629:Waist-Hip Ratio
chemical_list: D000418:Albumins