Spinal fibrous hamartoma of infancy: case report.
OBJECTIVE
Fibrous hamartoma of infancy (FHI) in the spinal cord is very rare. It is characterized histopathologically by three elements: fibrous, adipose, and myxoid mesenchymal tissues.


METHODS
A 10-month-old boy presented with paraparesis. Magnetic resonance imaging showed a large intradural mass that occupied the space between the T10 and L4 levels.


METHODS
We performed partial removal of the mass. Histopathological examination of the lesion revealed that it was composed of collagen bundles and fibrous tissue interspersed with adipose tissue, mesenchymal tissue, and glial tissue, and it was diagnosed as FHI.


CONCLUSIONS
FHI in the central nervous system, especially in the spine, is very rare, and the presence of glial tissue admixed with particular components of FHI is quite exceptional.
Yano
Shunsuke
S
Department of Neurosurgery, University of Hokkaido, Graduate School of Medicine, Sapporo, Japan. syano@med.hokudai.ac.jp
Hida
Kazutoshi
K
Nagashima
Kazuo
K
Iwasaki
Yoshinobu
Y
D000273:Adipose Tissue / Q000473:pathology; D003094:Collagen; D003937:Diagnosis, Differential; D006222:Hamartoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008648:Mesoderm / Q000473:pathology; D009457:Neuroglia / Q000473:pathology; D020335:Paraparesis / Q000209:etiology; D013118:Spinal Cord Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D013355:Subdural Space; D013904:Thoracic Vertebrae
D003094:Collagen