title: Development and characterization of porous silver-incorporated hydroxyapatite ceramic for separation and elimination of microorganisms.
abstract: A novel filter material for separating and eliminating microorganisms in water and gas was fabricated by incorporating silver ions into porous hydroxyapatite (HA) ceramics prepared by a starch additive technique. The porous ceramics reveal a microstructure of both large and small pores. Microorganism separating and eliminating properties of the porous silver-incorporated HA ceramics (PHA-Ag) were investigated by bacterial and viral filtration tests. The PHA-Ag demonstrated excellent separating and antibacterial effects on Escherichia coli and the mechanisms were studied. Adsorption of bacterial cells to the HA and the barricading effect of small pores contribute to the separating property of PHA-Ag, while the Ag+ ions equip the ceramics with antibacterial property. Furthermore, the PHA-Ag exhibited an observable virus-eliminating property and its probable mechanism was also discussed.
authors.affiliation: State Key Laboratory of New Ceramics and Fine Processing, Department of Materials Science and Engineering, Tsinghua University, Beijing 100084, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Xiaoshan
authors.initials: X
authors.lastname: Ning
authors.forename: Qunfang
authors.initials: Q
authors.lastname: Xiao
authors.forename: Kexin
authors.initials: K
authors.lastname: Chen
authors.forename: Heping
authors.initials: H
authors.lastname: Zhou
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002516:Ceramics / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D004926:Escherichia coli / Q000302:isolation & purification; D005374:Filtration / Q000295:instrumentation; D006367:HeLa Cells; D006801:Humans; D008851:Micropore Filters / Q000382:microbiology* / Q000821:virology; D016062:Porosity; D012834:Silver / Q000737:chemistry*; D014780:Viruses / Q000302:isolation & purification
chemical_list: D001672:Biocompatible Materials; D012834:Silver; D017886:Durapatite