title: Intracardiac thrombus and pulmonary embolism with cavitation and pneumomediastinum in a patient with protein S deficiency.
abstract: We present a case of intracardiac thrombus with pulmonary embolism and pulmonary infarction in a patient with protein S deficiency. Secondary infection of the pulmonary infarction resulted in pneumomediastinum. Thrombus in an unusual location in a young patient without known predisposing conditions is a characteristic feature of a hereditary thrombophilic disorder. Cavitation within a lesion adjacent to the mediastinal pleura can result in pneumomediastinum.
authors.affiliation: Department of Radiology, University Hospital, UMDNJ-NJ Medical School, Newark, NJ 07103-2406, USA. maldjipd@umdnj.edu
authors.forename: Pierre D
authors.initials: PD
authors.lastname: Maldjian
authors.forename: Jonelle M
authors.initials: JM
authors.lastname: Petscavage
mesh_terms: D000328:Adult; D003287:Contrast Media; D005260:Female; D006331:Heart Diseases / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D017380:Hypertrophy, Right Ventricular / Q000150:complications / Q000175:diagnosis; D008478:Mediastinal Emphysema / Q000150:complications* / Q000175:diagnosis; D017293:Protein S / Q000032:analysis; D018455:Protein S Deficiency / Q000150:complications* / Q000175:diagnosis; D011655:Pulmonary Embolism / Q000150:complications* / Q000175:diagnosis; D013927:Thrombosis / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D017293:Protein S