[Application of real-time tissue elastography in diagnosis of breast cancer].
To investigate the clinical value of real-time tissue elastography (RTE) in the diagnosis of breast cancer.



One hundred and twenty patients with breast lumps (135 lesions) were examined with B-mode imaging, color Doppler flowing imaging (CDFI) and RTE. The elastogram was graded using 5-score evaluating method. The postoperative pathological diagnosis was used as gold standard, and the sensitivity, specificity and accuracy of RTE and two-dimensional ultrasonography combined with RTE in diagnosis of breast cancer were calculated.



When the score >4 was set for cut-off criteria of malignancy, the sensitivity, specificity and accuracy of RTE was 85.45%, 83.75% and 84.4%, respectively. While two-dimensional ultrasonography combined with RTE was used, the sensitivity, specificity and accuracy increased up to 100%, 95% and 97%, respectively.



RTE combined with two-dimensional ultrasonography can improve the validity in the diagnosis of malignant breast lesions.
Zhang
Xiu-fang
XF
Department of Ultrasonography, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Liu
Xue-ming
XM
Bao
Xiao-feng
XF
Peng
Xian-jing
XJ
Zhang
Wen
W
Xu
Jun
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D003199:Computer Systems; D003937:Diagnosis, Differential; D004548:Elasticity; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary / Q000295:instrumentation*