title: Combined central retinal artery and vein occlusion secondary to systemic non-Hodgkin's lymphoma.
abstract: We report a rare case of low-grade systemic B-cell non-Hodgkin's lymphoma (NHL) causing central retinal artery and vein occlusion, which was the only manifestation of disease recurrence. A young man with resolved systemic NHL underwent fluorescein angiography, magnetic resonance imaging and computed tomography to investigate a severe unilateral visual loss. A combined vascular occlusion was observed in the right eye. Neuroimaging detected optic nerve infiltration; but no systemic/ central nervous system involvement was observed. The patient was treated with high-doses of corticosteroids and optic nerve irradiation. The optic neuropathy and vascular occlusion were resistant to treatment. The subsequent neovascular glaucoma was treated by panretinal photocoagulation, which relieved the pain, but vision was not recovered. No further recurrence was observed over the following year.
authors.affiliation: Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India. daksh@aravind.org
authors.forename: Dhananjay
authors.initials: D
authors.lastname: Shukla
authors.forename: Amit
authors.initials: A
authors.lastname: Arora
authors.forename: Khazaei M
authors.initials: KM
authors.lastname: Hadi
authors.forename: Mahesh
authors.initials: M
authors.lastname: Kumar
authors.forename: Satish
authors.initials: S
authors.lastname: Baddela
authors.forename: Ramasamy
authors.initials: R
authors.lastname: Kim
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D015356:Retinal Artery Occlusion / Q000175:diagnosis / Q000209:etiology*; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed