title: Long-term outcome of implanted cardioverter defibrillators in survivors of out-of-hospital cardiac arrest of cardiac origin.
abstract: BACKGROUND
  Little is known about the long-term outcome of implantable cardioverter defibrillator (ICD) therapy in survivors of out-of-hospital cardiac arrest (OHCA).
  
  
  RESULTS
  The frequency of lethal ventricular arrhythmias and whether ICD implantation can prevent recurrence of cardiac arrest were examined. Long-term (24.4+/-11.9 months) outcome was examined in 23 patients with OHCA who were treated with an ICD (OHCA group) and 35 patients without OHCA (non-OHCA group) who were treated with an ICD. Patients in both groups had same clinical backgrounds; however, those in the OHCA group showed a significantly lower incidence of induced ventricular arrhythmias (71%) than the non-OHCA group (96%). In the follow-up period, patients in the OHCA group had almost the same incidence of ICD discharge (30%) as patients in the non-OHCA group (40%). The rate of recurrence of ventricular fibrillation in the OHCA patients was 13%, and it was difficult to estimate the rate by induced ventricular arrhythmia.
  
  
  CONCLUSIONS
  The results suggest that ICD implantation for survivors of OHCA with favorable neurological recovery might be effective for preventing recurrence of cardiac arrest.
authors.affiliation: Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan.
authors.forename: Daigo
authors.initials: D
authors.lastname: Nagahara
authors.forename: Mamoru
authors.initials: M
authors.lastname: Hase
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Tsuchihashi
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Kokubu
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sakurai
authors.forename: Takuji
authors.initials: T
authors.lastname: Yoshioka
authors.forename: Kimio
authors.initials: K
authors.lastname: Nishizato
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Fujii
authors.forename: Kikuya
authors.initials: K
authors.lastname: Uno
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Miura
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ura
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Asai
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Shimamoto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000401:mortality / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D017147:Defibrillators, Implantable; D005260:Female; D005500:Follow-Up Studies; D006323:Heart Arrest / Q000401:mortality* / Q000628:therapy; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000401:mortality / Q000628:therapy