title: Herpes simplex virus type 2 (HSV-2) infection in women attending an antenatal clinic in the South Pacific island nation of Vanuatu.
abstract: OBJECTIVE
  The objective of this study was to estimate the prevalence and correlates of herpes simplex virus type 2 infection in women in an antenatal clinic in the South Pacific island nation of Vanuatu.
  
  
  METHODS
  A prevalence survey of sexually transmitted infections of pregnant women attending an antenatal clinic at Vila Central Hospital was conducted in 1999-2000. Serum samples were tested for HSV-1 and HSV-2 antibodies by enzyme-linked immunosorbent assay. Results for other sexually transmitted infections and demographic and obstetric variables were analyzed for their association with HSV-2 serostatus.
  
  
  RESULTS
  HSV-2 serum antibody results were obtained on 535 women and HSV-1 results on 134. The seroprevalence of HSV-2 was 30% and HSV-1 was 100%. On multivariate analysis, the independent predictors of HSV-2 infection were age, marital status, and trichomoniasis.
  
  
  CONCLUSIONS
  HSV-2 was common in this sample of sexually active women in Vanuatu. This is the first study of HSV in Vanuatu and one of very few studies in the Pacific region.
authors.affiliation: Sexually Transmitted Infections Research Centre, Westmead, New South Wales, Australia.
authors.forename: Lewis J
authors.initials: LJ
authors.lastname: Haddow
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Sullivan
authors.forename: Janette
authors.initials: J
authors.lastname: Taylor
authors.forename: Myriam
authors.initials: M
authors.lastname: Abel
authors.forename: Anthony L
authors.initials: AL
authors.lastname: Cunningham
authors.forename: Sepehr
authors.initials: S
authors.lastname: Tabrizi
authors.forename: Adrian
authors.initials: A
authors.lastname: Mindel
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006561:Herpes Simplex / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D018259:Herpesvirus 1, Human / Q000276:immunology / Q000302:isolation & purification*; D018258:Herpesvirus 2, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D011295:Prenatal Care; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires; D009514:Vanuatu / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral