The subcellular localization of the mammalian proteome comes  a fraction closer.
Another step along the road towards determining the subcellular localization of a complete mammalian proteome has been taken with a study using cellular fractionation and protein correlation profiling to identify and localize organellar proteins. Here we discuss this new work in the context of other strategies for large-scale subcellular localization.
Simpson
Jeremy C
JC
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. simpson@embl.de
Pepperkok
Rainer
R
D000818:Animals; D019295:Computational Biology; D005786:Gene Expression Regulation; D006801:Humans; D013058:Mass Spectrometry; D051379:Mice; D016366:Open Reading Frames; D020543:Proteome / Q000032:analysis*; D013347:Subcellular Fractions / Q000737:chemistry
D020543:Proteome