Angeli-Rimini's reaction on solid support: a new approach to hydroxamic acids.
Angeli-Rimini's reaction has been performed for the first time on solid phase. A convenient one-step procedure for the synthesis of hydroxamic acids starting from aldehydes and solid-supported N-hydroxybenzenesulfonamide is reported. The hydroxamates are isolated in good to high yields and purities by simple evaporation of the volatile solvents, after treatment of the crude reaction mixture with sequestering agents.
Porcheddu
Andrea
A
Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy. anpo@uniss.it
Giacomelli
Giampaolo
G
D000447:Aldehydes / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006877:Hydroxamic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D012680:Sensitivity and Specificity
D000447:Aldehydes; D006877:Hydroxamic Acids