A single somatic activating Asp578His mutation of the luteinizing hormone receptor causes Leydig cell tumour in boys with gonadotropin-independent precocious puberty.
d'Alva
Catarina B
CB
Brito
Vinicius N
VN
Palhares
Heloisa M C
HM
Carvalho
Filomena M
FM
Arnhold
Ivo J P
IJ
Mendonca
Berenice B
BB
Latronico
Ana Claudia
AC
D002648:Child; D006801:Humans; D007984:Leydig Cell Tumor / Q000235:genetics*; D008297:Male; D017354:Point Mutation; D011629:Puberty, Precocious / Q000235:genetics*; D011974:Receptors, LH / Q000235:genetics*; D013736:Testicular Neoplasms / Q000235:genetics*
D011974:Receptors, LH