title: Medicinal chemistry of hERG optimizations: Highlights and hang-ups.
authors.affiliation: Medicinal Chemistry, Organon Laboratories Ltd., Newhouse, Lanarkshire ML1 5SH, Scotland, UK.
authors.forename: Craig
authors.initials: C
authors.lastname: Jamieson
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Moir
authors.forename: Zoran
authors.initials: Z
authors.lastname: Rankovic
authors.forename: Grant
authors.initials: G
authors.lastname: Wishart
mesh_terms: D000818:Animals; D001665:Binding Sites; D002626:Chemistry, Pharmaceutical / Q000379:methods; D051638:Ether-A-Go-Go Potassium Channels / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000502:physiology; D006801:Humans; D015394:Molecular Structure; D026902:Potassium Channel Blockers / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D051638:Ether-A-Go-Go Potassium Channels; D026902:Potassium Channel Blockers