title: The contribution of accommodation and the ocular surface to the microfluctuations of wavefront aberrations of the eye.
abstract: We have used videokeratoscopy and wavefront sensing to investigate the contribution of the ocular surface and the effect of stimulus vergence on the microfluctuations of the wavefront aberrations of the eye. The fluctuations of the wavefront aberrations were quantified by their variations around the mean and by using power spectrum analysis. Integrated power was determined in two regions: 0.1-0.7 Hz (low frequencies) and 0.8-1.8 Hz (high frequencies). Changes in the ocular surface topography were measured using high-speed videokeratoscopy and variations in the ocular wavefront aberrations were measured with a wavefront sensor. The microfluctuations of wavefront aberrations of the ocular surface were found to be considerably smaller than the microfluctuations of the wavefront aberrations of the total eye. The fluctuations in defocus while viewing a closer target at 2 or 4 D were found to be significantly greater than fluctuations in defocus when viewing a far target. This increase in defocus fluctuations (p < or = 0.001) occurred in both the low- and high-frequency regions of the power spectra.
authors.affiliation: Contact Lens and Visual Optics Laboratory, School of Optometry, Queensland University of Technology, Victoria Park Road, Kelvin Grove 4059, Queensland, Australia. zhum@upmc.edu
authors.forename: Mingxia
authors.initials: M
authors.lastname: Zhu
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Collins
authors.forename: D Robert
authors.initials: DR
authors.lastname: Iskander
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000328:Adult; D001251:Astigmatism / Q000503:physiopathology; D003290:Convergence, Ocular / Q000502:physiology; D019781:Corneal Topography / Q000379:methods; D003941:Diagnostic Techniques, Ophthalmological; D005123:Eye / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D012029:Refraction, Ocular / Q000502:physiology; D012030:Refractive Errors / Q000473:pathology / Q000503:physiopathology*; D013997:Time Factors