Lipoxidation-derived reactive carbonyl species as potential drug targets in preventing protein carbonylation and related cellular dysfunction.
Aldini
Giancarlo
G
Institute of Pharmaceutical and Toxicological Chemistry Pietro Pratesi, Faculty of Pharmacy, University of Milan, Viale Abruzzi 42, 20131, Milan, Italy.
Dalle-Donne
Isabella
I
Colombo
Roberto
R
Maffei Facino
Roberto
R
Milzani
Aldo
A
Carini
Marina
M
D000447:Aldehydes / Q000378:metabolism*; D000818:Animals; D016923:Cell Death / Q000187:drug effects; D016166:Free Radical Scavengers / Q000494:pharmacology; D017127:Glycation End Products, Advanced / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007659:Ketones / Q000378:metabolism*; D015227:Lipid Peroxidation; D015394:Molecular Structure; D050050:Protein Carbonylation / Q000187:drug effects; D017382:Reactive Oxygen Species / Q000378:metabolism
D000447:Aldehydes; D016166:Free Radical Scavengers; D017127:Glycation End Products, Advanced; D007659:Ketones; D017382:Reactive Oxygen Species