Synthesis of brominated directly fused diporphyrins through gold(III)-mediated oxidation.
Highly efficient synthesis of meso,meso-dibromo doubly and triply fused diporphyrins has been achieved through a powerful oxidative coupling mediated by AuCl3-AgOTf combination. In addition, palladium-catalyzed debromination of meso-bromoporphyrins has been developed. This debromination protocol enables employment of bromine as a protecting group for the reactive meso-position of porphyrins.
Sahoo
Akhila K
AK
Department of Chemistry, Graduate School of Science, Kyoto University and CREST, Japan Science and Technology Agency (JST), Kyoto University, Kyoto 606-8502, Japan.
Nakamura
Yasuyuki
Y
Aratani
Naoki
N
Kim
Kil Suk
KS
Noh
Su Bum
SB
Shinokubo
Hiroshi
H
Kim
Dongho
D
Osuka
Atsuhiro
A
D001966:Bromine / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011166:Porphyrins / Q000138:chemical synthesis*
D011166:Porphyrins; D006046:Gold; D001966:Bromine