[Study on the supercritical carbon dioxide extraction of Brucea Javanica oil].
The technics of supercritical carbon dioxide extraction of Brucea Javanica for injection oil was studied. The effects of the conditions of extraction and separation on extraction oil yield and quality were investigated and the effects of extraction pressure and separation pressure on acid number of the oil were discussed. So the optimal condition of this method was determined. With a quality evaluation, the Brucea Javanica oil extracted with supercritical CO2 agreed with the quality standard of refined Brucea Javanica oil for injection. This method shows sufficiently the advantages of supercritical CO2 extraction applied in the extraction of traditional Chinese medicine.
Ge
Fa-Huan
FH
National Engineering Research Center for Modernization of Extraction and Separation Process of TCM, Guangzhou 510204, China.
Lei
Hua-Ping
HP
D032269:Brucea / Q000737:chemistry*; D002245:Carbon Dioxide; D025924:Chromatography, Supercritical Fluid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification* / Q000592:standards; D005227:Fatty Acids / Q000032:analysis; D005638:Fruit / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D010938:Plant Oils / Q000302:isolation & purification* / Q000592:standards; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature
D004365:Drugs, Chinese Herbal; D005227:Fatty Acids; D010938:Plant Oils; D002245:Carbon Dioxide