Triglycerides and high-density lipoprotein cholesterol are associated with insulinemia in adolescents.
OBJECTIVE
The aim of this study was to evaluate the association between lipids and insulin concentration in adolescents.


METHODS
A cross-sectional study of 350 adolescents aged 14-19 years old from a public high school in Guadalajara, in the state of Jalisco, Mexico, was conducted. Fasting insulin concentration was determined using microparticle enzyme immunoassay; total cholesterol and triglycerides were detected by standard enzymatic procedures;and low- and high-density lipoproteins were found using standard precipitation methods. Statistical analysis included linear multivariate regression.


RESULTS
Serum triglycerides were associated positively with insulin fasting (beta = 0.003, p = 0.0001) and high-density lipoprotein cholesterol was negatively associated with insulin fasting in male adolescents 18-19 years old (beta = -0.03, p = 0.012).


CONCLUSIONS
The relationships between triglycerides and insulin and between high-density lipoprotein cholesterol and insulin are already present in adolescence.
Ramírez-López
Guadalupe
G
Unidad de Investigación Epidemiológica y en Servicios de Salud del Adolescente, Instituto Mexicano del Seguro Social, Guadalajara, Jal., México. maria.ramirezlo@imss.gob.mx
González-Villalpando
Clicerio
C
Salmerón
Jorge
J
González-Ortiz
Manuel
M
Valles-Sánchez
Victoria
V
D000293:Adolescent; D000328:Adult; D008076:Cholesterol, HDL / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood* / Q000453:epidemiology*; D014280:Triglycerides / Q000097:blood*
D008076:Cholesterol, HDL; D007328:Insulin; D014280:Triglycerides