[The effect of melatonin on prolactin, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) synthesis and secretion].
This paper reviews the data on the role of the pineal gland and melatonin in the regulation of hypothalamo-adenohypophysial system activity. The results of in vivo and in vitro experiments show that the effect of melatonin on prolactin, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) synthesis and secretion depends on the animal species, age, sex, the concentration of the hormone, and experimental conditions. Moreover, the melatonin-responsive pars tuberalis of the pituitary is an intermediary in the control of prolactin secretion, while the melatonin-binding sites of the mediobasal hypothalamus are involved in the gonadotropic response to melatonin.
Juszczak
Marlena
M
Zakład Patofizjologii i Neuroendokrynologii Doświadczalnej, Katedry Patologii Ogólnej i Doświadczalnej, Uniwersytetu Medycznego w Łodzi. marlenaj@bg.umed.lodz.pl
Michalska
Monika
M
D000818:Animals; D005640:Follicle Stimulating Hormone / Q000096:biosynthesis / Q000378:metabolism; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007986:Luteinizing Hormone / Q000096:biosynthesis / Q000378:metabolism; D008550:Melatonin / Q000378:metabolism*; D010870:Pineal Gland / Q000502:physiology*; D011388:Prolactin / Q000096:biosynthesis / Q000378:metabolism
D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D008550:Melatonin