title: [Mantle-cell lymphoma of the ocular adnexa: a case report].
abstract: Ocular adnexal lymphoid tumors are slow-growing neoplasms that affect predominantly the elderly. The purpose of this study is to report a non-Hodgkin lymphoma from mantle zone cells, a rare ocular annexal B-cell lymphoma subtype.
  
  
  METHODS
  A 62-year-old male patient with superior eyelid, maxillary and oral tumours, had an initial diagnosis of Mikulics disease, developed lesion enlargement, despite immunosuppressant therapy. Left superior eyelid and bone marrow biopsy revealed non-Hodgkin lymphoma the mantle zone. In spite of dissemination (stage IV), chemotherapy and bone marrow transplant led to disease remission.
  Despite the availability of advanced complementary diagnostic methods, like immunophenotyping and molecular genetic analysis, lymphoma represents, for physicians and pathologists, a challenge regarding diagnosis and prognosis.
authors.affiliation: Departamento de Plástica Ocular, Dr. Homero de Miranda Gomes Hospital Regional de São José, São José, SC, Brazil.
authors.forename: Anna Paula Lemos
authors.initials: AP
authors.lastname: de Albuquerque
authors.forename: Jonathan Seiji
authors.initials: JS
authors.lastname: Aguni
authors.forename: Renato José Bett
authors.initials: RJ
authors.lastname: Correia
authors.forename: Franciele
authors.initials: F
authors.lastname: Vegini
authors.forename: André Dalsasso Borges
authors.initials: AD
authors.lastname: de Souza
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D001706:Biopsy; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome