Protein synthesis molecule by molecule.
Since the earliest days of molecular biology it has been known that even a seemingly uniform culture of bacteria is made up of cells very different from each other in terms of their levels of a given protein. This individuality has now finally been quantified at single-molecule resolution, as reported in two recent papers.
Golding
Ido
I
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. igolding@princeton.edu
Cox
Edward C
EC
D000818:Animals; D004023:Dictyostelium / Q000235:genetics / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D049452:Green Fluorescent Proteins / Q000032:analysis / Q000235:genetics; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D001616:beta-Galactosidase / Q000378:metabolism
D012333:RNA, Messenger; D049452:Green Fluorescent Proteins; D001616:beta-Galactosidase