title: Treatment of systemic mastocytosis.
abstract: It is an exciting time in the treatment of systemic mastocytosis. Major advances in the past 2 decades have helped to define the molecular abnormalities associated with this disease and to delineate pathways involved in its pathogenesis. This has directly translated into the development of novel targeted therapies. These therapies hold great promise to patients and health care providers that a "cure" for systemic mastocytosis may someday be obtainable.
authors.affiliation: Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11C205, 10 Center Drive, MSC 1881, Bethesda, MD 20892, USA.
authors.forename: Todd M
authors.initials: TM
authors.lastname: Wilson
authors.forename: Dean D
authors.initials: DD
authors.lastname: Metcalfe
authors.forename: Jamie
authors.initials: J
authors.lastname: Robyn
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D003376:Counseling; D006801:Humans; D018836:Inflammation Mediators / Q000276:immunology; D034721:Mastocytosis, Systemic / Q000628:therapy*; D010353:Patient Education as Topic
chemical_list: D000970:Antineoplastic Agents; D018836:Inflammation Mediators