[Anticarnosine activity of staphylococci as a criterion for assessment of their persistence potential].
The analysis on clinical material and the use of experimental models allowed to prove the role of anticarnosine activity of staphylococci in their persistence. Light and electronic microscopy revealed large destruction of ultrastructural eukaryote components and decreased proliferative activity in animals challenged with strains characterized by high anticarnosine activity. Adaptive mechanisms, providing dynamic equilibrium in "eukaryote--prokaryote" system, are described.
Kartashova
O L
OL
Kirgizova
S B
SB
Stadnikov
A A
AA
Shevliuk
N N
NN
Kovbyk
L V
LV
Chuenko
E A
EA
D000293:Adolescent; D000818:Animals; D001685:Biological Factors / Q000378:metabolism*; D002336:Carnosine / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D002648:Child; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology*; D006801:Humans; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D051381:Rats; D040141:Staphylococcaceae / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
D001685:Biological Factors; D002336:Carnosine