Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils.
Essential oils of Salvia macrochlamys and Salvia recognita were obtained by hydrodistillation of dried aerial parts and characterized by gas chromatography and gas chromatography-mass spectrometry. One hundred and twenty identified constituents representing 97.7% in S. macrochlamys and 96.4% in S. recognita were characterized, and 1,8-cineole, borneol, and camphor were identified as major components of the essential oils. The oils were evaluated for their antimalarial, antimicrobial, and antifungal activities. Antifungal activity of the essential oils from both Salvia species was nonselective at inhibiting growth and development of reproductive stroma of the plant pathogens Colletotrichum acutatum, Colletotrichum fragariae, and Colletotrichum gloeosporioides. S. macrochlamys oil had good antimycobacterial activity against Mycobacterium intracellulare; however, the oils showed no antimicrobial activity against human pathogenic bacteria or fungi up to a concentration of 200 microg/mL. S. recognita oil exhibited a weak antimalarial activity against Plasmodium falciparum.
Tabanca
Nurhayat
N
U.S. Department of Agriculture, ARS, NPUPU, The University of Mississippi, University, Mississippi 38677, USA.
Demirci
Betul
B
Baser
Kemal Husnu Can
KH
Aytac
Zeki
Z
Ekici
Murat
M
Khan
Shabana I
SI
Jacob
Melissa R
MR
Wedge
David E
DE
D000890:Anti-Infective Agents / Q000494:pharmacology; D000962:Antimalarials / Q000494:pharmacology; D001892:Camphanes / Q000032:analysis; D002164:Camphor / Q000032:analysis; D002849:Chromatography, Gas; D020231:Colletotrichum / Q000187:drug effects; D003511:Cyclohexanols / Q000032:analysis; D000077591:Eucalyptol; D005659:Fungicides, Industrial / Q000494:pharmacology*; D008401:Gas Chromatography-Mass Spectrometry; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D027544:Salvia / Q000737:chemistry*
D000890:Anti-Infective Agents; D000962:Antimalarials; D001892:Camphanes; D003511:Cyclohexanols; D005659:Fungicides, Industrial; D039821:Monoterpenes; D009822:Oils, Volatile; D002164:Camphor; C022871:isoborneol; D000077591:Eucalyptol