title: Incidence of sepsis in hospitalized patients.
abstract: In recent years, several epidemiological studies have helped expand our knowledge of the incidence of sepsis at the intensive care unit (ICU) and population levels. However, more data are needed from developing countries. Overall, even with a lack of standardized definitions--particularly of sepsis-associated organ dysfunction, hypoperfusion or hypotension, and septic-induced cardiovascular failure despite adequate fluid resuscitation--the incidence of sepsis seems higher in Brazil, the United Kingdom, and Portugal. In the future, in order to better identify patients that need early ICU admission, aggressive care, and new therapies, we must develop and apply better instruments for definition and risk stratification, especially for evaluating the risk of progressing from sepsis to severe sepsis and septic shock.
authors.affiliation: Unidade de Cuidados Intensivos Polivalente, Hospital de Santo António dos Capuchos, Alameda de Santo António dos Capuchos, 1169-050 Lisboa, Portugal. r.moreno@mail.telepac.pt
authors.forename: Rui
authors.initials: R
authors.lastname: Moreno
authors.forename: Susana
authors.initials: S
authors.lastname: Afonso
authors.forename: Teresa
authors.initials: T
authors.lastname: Fevereiro