[Relationships among vitamin D receptor gene and calcium absorption, bone mass].
The association between vitamin D receptor gene polypmorphisms and bone mass is controversial. Many studies have found polymorphism of vitamin D receptor (VDR) gene be associated with bone mass. But some studies show no association between vitamin D receptor gene polymorphism and bone mass. The relationships among vitamin D receptor gene and calcium absorption, bone mass, drug treatment are reviewed in this article. The interaction between genetic, environmental factors to bone mass is also reviewed.
Tong
Zhi-Qin
ZQ
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Ma
Guan-Sheng
GS
D015519:Bone Density; D002118:Calcium / Q000493:pharmacokinetics*; D006801:Humans; D007408:Intestinal Absorption; D010024:Osteoporosis / Q000209:etiology / Q000235:genetics*; D011110:Polymorphism, Genetic; D018167:Receptors, Calcitriol / Q000235:genetics*
D018167:Receptors, Calcitriol; D002118:Calcium