Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi.
Neres
João
J
Wolfson Centre for Structure-Based Design of Molecular Diagnostics, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester M13 9PL, UK.
Buschiazzo
Alejandro
A
Alzari
Pedro M
PM
Walsh
Lindsey
L
Douglas
Kenneth T
KT
D000818:Animals; D004791:Enzyme Inhibitors / Q000032:analysis*; D005470:Fluorometry / Q000379:methods*; D006023:Glycoproteins / Q000037:antagonists & inhibitors*; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D014349:Trypanosoma cruzi / Q000201:enzymology*
D004791:Enzyme Inhibitors; D006023:Glycoproteins; C069715:trans-sialidase; D009439:Neuraminidase