Nanoscale controlled self-assembled monolayers and quantum dots.
Self-assembled monolayer (SAM) and fluorescent quantum dots (QDs) share common ground as emerging tools for nanoscale observation of biological interactions. SAMs provide excellent means of controlling the surface characteristics through individually tailored and engineered building blocks. SAMs on various surfaces have demonstrated clear advantages over uncontrolled multilayer films in fabricating electrochemical sensor, optical sensor, chemical biosensor, and atomic force microscopy. Similarly, QDs have advantages over organic fluorophores in long-term and real-time optical imaging of biological specimens. QDs conjugated with various biomolecules have been successfully applied to bioimaging, biosensing and cell encoding.
Shin
Seung Koo
SK
Bio-Nanotechnology Center, Department of Chemistry, Pohang University of Science and Technology, San 31 Hyoja-Dong, Pohang, Korea.
Yoon
Hye-Joo
HJ
Jung
Yu Jin
YJ
Park
Joon Won
JW
D000818:Animals; D015374:Biosensing Techniques / Q000379:methods; D018625:Microscopy, Atomic Force; D036103:Nanotechnology / Q000379:methods*; D045663:Quantum Dots; D012680:Sensitivity and Specificity; D013499:Surface Properties