title: Is histone loss a common feature of DNA metabolism regulation?
abstract: Chromatin modifications play a crucial role in regulating DNA metabolism. Chromatin structures can be remodeled by covalently modifying histones, by shifting nucleosomes along the DNA, and by changing the histone composition of nucleosomes. Lately, nucleosome displacement has been extensively described within transcribed genes and DNA breaks. This review focuses on recently published work that describes the relationships between histone modification/exchange and nucleosome displacement.
authors.affiliation: CNRS CGM, 1, avenue de la terrasse, 91198 Gif/Yvette cedex, France. antonin.morillon@cgm.cnrs-gif.fr
authors.forename: Antonin
authors.initials: A
authors.lastname: Morillon
mesh_terms: D000818:Animals; D042002:Chromatin Assembly and Disassembly; D004247:DNA / Q000235:genetics / Q000378:metabolism*; D004249:DNA Damage; D006657:Histones / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008745:Methylation; D008957:Models, Genetic; D018832:Molecular Chaperones / Q000235:genetics; D009707:Nucleosomes / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D017027:Protein Tyrosine Phosphatases / Q000235:genetics; D054558:Protein Tyrosine Phosphatases, Non-Receptor; D014158:Transcription, Genetic
chemical_list: D006657:Histones; D018832:Molecular Chaperones; D009707:Nucleosomes; D004247:DNA; D017027:Protein Tyrosine Phosphatases; D054558:Protein Tyrosine Phosphatases, Non-Receptor; C475072:SBF2 protein, human