The prevalence of sight-threatening uveitis in Scotland.
OBJECTIVE
To identify and quantify the prevalence of patients with uveitis receiving systemic immunosuppression in Scotland.


METHODS
Anonymised data were prospectively collected on all patients with uveitis requiring systemic immunosuppression. Seven health boards participated over a 4-month period between 1 August 2005 and 30 November 2005.


RESULTS
373 patients were identified, of whom 205 (55%) were female. The mean age was 46.4 (range 7-97 years). Using the data from the seven participating health boards, an estimated Scottish prevalence of 9 per 100 000 was calculated. Prevalence varied between 2 and 59 per 100 000. In National Health Service Grampian, all patients with uveitis, whether sight-threatening or not, are followed up at a specialist clinic. Extrapolating this figure to Scotland gives a prevalence of 25 per 100 000.


CONCLUSIONS
The data from National Health Service Grampian suggest that there is a significant shortfall in the number of patients identified by survey. If the "missing population" exists, then where are they? Some might be receiving appropriate treatment at non-specialist clinics, although simple under-reporting may play a part. Greater concern is for those patients receiving inappropriate treatment for their uveitis, or for those within the community who are either oblivious to or in self denial of their condition.
Williams
G J
GJ
Grampian University Hospitals NHS Trust, Department of Ophthalmic Medicine, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZD, Scotland.
Brannan
S
S
Forrester
J V
JV
Gavin
M P
MP
Paterson-Brown
S P
SP
Purdie
A T
AT
Virdi
M
M
Olson
J A
JA
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness / Q000209:etiology; D002648:Child; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012606:Scotland / Q000453:epidemiology; D017678:Sex Distribution; D014605:Uveitis / Q000150:complications / Q000453:epidemiology* / Q000276:immunology