The value of ultrasonography alone in screening surveys of cystic echinococcosis in children in Turkey.
A total of 1,205 primary school children were examined for cystic echinococcosis in five villages of Manisa, Turkey, to evaluate the efficacy of diagnostic methods of this infection in community-based screening surveys. Six hundred and thirty children from three villages, examined by a portable ultrasound scanner, chest microfilm and serological methods (ELISA, indirect hemagglutination) in our previous study, were designated as Study Group 1; and 575 children, from two adjacent villages, examined by ultrasonography alone in the present study, were designated as Study Group 2. In Study Group 1, hepatic cystic echinococcosis was detected in two cases (0.3%) by ultrasonography, while 43 (8.9%) and 49 (10.1%) cases were found to be positive for cystic echinococcosis by ELISA and indirect hemagglutination, respectively. Three of 575 children (0.5%) were diagnosed with cystic echinococcosis (two hepatic and one renal involvement) by ultrasonography alone in Study Group 2; and lung lesions were later detected in both cases with liver involvement by chest radiography. Our results suggested that serological tests may be beneficial in suspected cases for confirmation and differential diagnosis, but have some drawbacks, such as discrepancy in results and high false seropositivity rates. Chest microfilm is not easy in field studies and exposure to X-ray is undesirable. As a reliable, simple, inexpensive and rapid technique, ultrasonography alone is recommended to be used in community-based screening surveys for cystic echinococcosis with confirmatory tests for suspected cases found during the screening program.
Kilimcioğlu
Ali A
AA
Department of Parasitology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey. ali.kilimcioglu@bayar.edu.tr
Ozkol
Mine
M
Bayindir
Petek
P
Girginkardeşler
Nogay
N
Ostan
Ipek
I
Ok
Ulgen Z
UZ
D000293:Adolescent; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D002648:Child; D004443:Echinococcosis / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D048209:Echinococcus granulosus / Q000302:isolation & purification*; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D011237:Predictive Value of Tests; D015995:Prevalence; D013902:Radiography, Thoracic / Q000191:economics / Q000379:methods; D012698:Serologic Tests / Q000191:economics / Q000379:methods; D014421:Turkey / Q000453:epidemiology; D014463:Ultrasonography
D000913:Antibodies, Protozoan