title: [Status of vitamin A, vitamin B2, iron and an-oxidantive activity in anemic pregnant women in China].
abstract: OBJECTIVE
  To investigate the status of vitamin A(VA), vitamin B2 (VB2), iron and anoxidative function in anemic and non-anemic pregnant women.
  
  
  METHODS
  426 anemic and 36 non-anemic pregnant women were included in the study. The survey of 24-hour's diet recall of pregnant women was made to evaluate intake of iron, VB2, folic acid, etc by the nutrition software provided by Beijing 301 hospital, iron and VA were measured by Radioimmunoassay (RIA) and by high-pressure liquid chromatography. VB2 status was detected using the assay for erythrocyte glutathione reductase (Egr; EC 1.6.4.2) activity. SOD and GSH-Px activities and MDA were determined using commercial kits. Peripheral blood erythrocyte membrane fluidity was detected by using 1,6-diphenyl-1,3,5-hexatriene as a probe, the degree of fluorescence polarization (P) at 25 degrees C of disrupted cells plasma membranes were compared for a variety of systems.
  
  
  RESULTS
  Median intakes of protein and vitamin C met the current Chinese RNIs for pregnancy, whereas intakes of(VA) and VB2 were well below the recommendations. Intake of iron were above 90%, but the main sources of iron are vegetables. Plasma VA (1.25 micromol/L) and iron (20.57 microg/L) were lower, BGRAC (1.79) was higher than that in non-anemia group (VA 1.57 micromol/L, SF 33.16 microg/L, BGRAC 1.52). The level of plasma SOD (77.1U/ml) and the activity of GSH-Px (61.9U) were lower than those in non-anemia group (92.2U/ml, 71.6U, P < 0.05), while MDA (4.58 nmol/ml) level and erythrocyte membrane (P = 0.2622, eta = 2.7465) fluidity were higher than those non-anemia group(MDA = 3.78 nmol/ ml, P = 0.2360, eta = 2.3658).
  
  
  CONCLUSIONS
  Plasam VA, VB2 and iron, antioxidantcapacity and erythrocyte membrane fluidity were decreased in the anemic pregnant women.
authors.affiliation: Department of Preventive Medicine, Liaocheng Professional College, Liaocheng 252000, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Ma
authors.forename: Xiu-Zhen
authors.initials: XZ
authors.lastname: Zhang
authors.forename: Dian-Chen
authors.initials: DC
authors.lastname: Jiang
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood*; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood*; D009752:Nutritional Status; D018384:Oxidative Stress / Q000502:physiology*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood*; D012256:Riboflavin / Q000097:blood*; D013482:Superoxide Dismutase / Q000378:metabolism; D014801:Vitamin A / Q000097:blood*; D055815:Young Adult
chemical_list: D014801:Vitamin A; D007501:Iron; D013482:Superoxide Dismutase; D012256:Riboflavin