title: Fibroblast cell attachment and growth on nanoengineered sculptured thin films.
abstract: Nanoengineered parylene-C sculptured thin films (STFs) are deposited on glass and silicon substrates using a direct one-step growth technique. The deposited STFs support fibroblast cell attachment and proliferation in vitro, which is an early indication of biocompatibility and bioactivity of this emerging class of biomaterials. Surface modification of endoprostheses of the small joints of the hand, which heal with fibrous stabilization, may be greatly enhanced by such nanoengineered biomaterials.
authors.affiliation: College of Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, USA. mdemirel@engr.psu.edu
authors.forename: M C
authors.initials: MC
authors.lastname: Demirel
authors.forename: E
authors.initials: E
authors.lastname: So
authors.forename: T M
authors.initials: TM
authors.lastname: Ritty
authors.forename: S H
authors.initials: SH
authors.lastname: Naidu
authors.forename: A
authors.initials: A
authors.lastname: Lakhtakia
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology*; D019556:COS Cells; D002448:Cell Adhesion; D049109:Cell Proliferation; D002522:Chlorocebus aethiops; D005347:Fibroblasts / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D005898:Glass / Q000737:chemistry; D008422:Materials Testing; D036103:Nanotechnology; D011108:Polymers / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry; D014992:Xylenes / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D014992:Xylenes; C011055:parylene; D012825:Silicon