title: [A case of heparin induced thrombocytopenia treated with lepirudin infusion: case report].
abstract: Heparin induced thrombocytopenia (HIT) is a life-threatening complication that can be seen in the course of heparin treatment. The syndrome is much likely to be seen during treatment with standard heparin but it can also be seen due to low molecular weight heparins. In this article, we presented a case of HIT who was given low molecular weight heparin for prophylaxis that developed massive pulmonary thromboembolism. The patient was successfully treated with lepirudin infusion and no complications due to treatment was seen.
authors.affiliation: Department of Chest Diseases, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. sulesunmez@yahoo.com
authors.forename: Sule
authors.initials: S
authors.lastname: Sünmez
authors.forename: Gülfer
authors.initials: G
authors.lastname: Okumuş
authors.forename: Esen
authors.initials: E
authors.lastname: Kiyan
authors.forename: Turhan
authors.initials: T
authors.lastname: Ece
authors.forename: Orhan
authors.initials: O
authors.lastname: Arseven
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects*; D006629:Hirudins / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000139:chemically induced / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D011859:Radiography; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000139:chemically induced / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D006629:Hirudins; D011994:Recombinant Proteins; C083544:lepirudin