title: Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review.
abstract: Vitamin E consists of a group of eight isomers, four tocopherols (alpha-, beta-, gamma-, delta-tocopherol) and four tocotrienols (alpha-, beta-, gamma-, delta-tocotrienol). While extensive literature has been published on the potential health benefits of alpha-tocopherol, little is known about gamma-tocopherol, the major form of vitamin E in food in the U.S. gamma-tocopherol has recently received more research attention based on findings from in vitro and animal studies indicating that it has potent anti-inflammatory and antioxidant properties. Based on these recent studies, it is important to investigate the possible health benefits of gamma-tocopherol in humans. In this article, we review publications on dietary gamma-tocopherol intake, plasma gamma-tocopherol levels, cardiovascular disease and cancer risk in humans.
authors.affiliation: Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Nutritional Epidemiology, Boston, MA 02111, USA. Marion.Dietrich@tufts.edu
authors.forename: Marion
authors.initials: M
authors.lastname: Dietrich
authors.forename: Maret G
authors.initials: MG
authors.lastname: Traber
authors.forename: Paul F
authors.initials: PF
authors.lastname: Jacques
authors.forename: Carroll E
authors.initials: CE
authors.lastname: Cross
authors.forename: Youqing
authors.initials: Y
authors.lastname: Hu
authors.forename: Gladys
authors.initials: G
authors.lastname: Block
mesh_terms: D004032:Diet; D006331:Heart Diseases / Q000097:blood / Q000517:prevention & control*; D006801:Humans; D009369:Neoplasms / Q000097:blood / Q000517:prevention & control*; D014815:Vitamins / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D024504:gamma-Tocopherol / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*
chemical_list: D014815:Vitamins; D024504:gamma-Tocopherol