[Immunological indices in differential diagnosis of active and inactive chronic endocervicitis].
A total of 132 patients were examined for chronical endocervicitis by clinical, immunological and morphological methods. According to the results obtained the patients were subdivided into several groups. The first group covered 77 females with an active clinical somatic form of the disease. The second group included 55 patients with chronical inactive endocervicitis. Controls included 25 practically healthy females. No differences were found between immunological indices of peripheral blood in groups of patients with active and inactive forms of chronic endocervicitis. Immunological tests on cervical mucus in patients with chronic endocervicitis revealed differences in the total number of leukocytes, content of living cells, functional activity of neutrophils, concentration of immunoglobulins and proinflammatory cytokines. This study may contribute to the development of immunological criteria for diagnosis of inflammatory process activity as well as a diagnostic model.
Dolgushina
V F
VF
Telesheva
L F
LF
Gol'tsfarb
V M
VM
Evtushenko
V P
VP
Savochkina
A Iu
AIu
Tupikov
V A
VA
D002353:Carrier State / Q000175:diagnosis* / Q000276:immunology; D002582:Cervix Mucus / Q000276:immunology*; D002908:Chronic Disease; D016207:Cytokines / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology*; D008247:Lysosomes / Q000378:metabolism; D009113:Muramidase / Q000032:analysis / Q000378:metabolism; D009504:Neutrophils / Q000201:enzymology / Q000276:immunology; D002575:Uterine Cervicitis / Q000175:diagnosis* / Q000276:immunology
D016207:Cytokines; D007136:Immunoglobulins; D009113:Muramidase