title: Improved method for the determination of zinc pyrithione in environmental water samples incorporating on-line extraction and preconcentration coupled with liquid chromatography atmospheric pressure chemical ionisation mass spectrometry.
abstract: A method has been developed for the determination of zinc pyrithione (ZnPT) in environmental water samples using monolithic reversed-phase silica columns for rapid on-line large volume solid phase extraction in tandem with on-line matrix removal using sacrificial strong anion exchange (SAX) columns. This is coupled with reversed-phase liquid chromatography with atmospheric pressure chemical ionisation mass spectrometric detection. Limits of detection in spiked river water samples, using a 200 mL preconcentration volume, were determined as 18 ng L(-1), with a limit of quantitation of 62 ng L(-1). The percentage recovery from spiked river water was found to be 72+/-9 (n=3 extractions), whilst overall method precision, following 10 repeat complete analyses was found to be 27% RSD at 1 microg L(-1). Linearity was determined over the concentration range of 0.25-10 microg L(-1) and the calculated regression coefficient was R(2)=0.9802. The method was used to investigate the environmental fate of zinc pyrithione in waters and its partition coefficient between sediment and water phases.
authors.affiliation: National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Bones
authors.forename: Kevin V
authors.initials: KV
authors.lastname: Thomas
authors.forename: Brett
authors.initials: B
authors.lastname: Paull
mesh_terms: D001274:Atmospheric Pressure; D002853:Chromatography, Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000032:analysis* / Q000737:chemistry; D011725:Pyridines / Q000032:analysis* / Q000737:chemistry; D015203:Reproducibility of Results; D014867:Water / Q000032:analysis* / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000737:chemistry
chemical_list: D009942:Organometallic Compounds; D011725:Pyridines; D014874:Water Pollutants, Chemical; D014867:Water; C010423:pyrithione zinc