Genetic architecture of the dog: sexual size dimorphism and functional morphology.
Purebred dogs are a valuable resource for genetic analysis of quantitative traits. Quantitative traits are complex, controlled by many genes that are contained within regions of the genome known as quantitative trait loci (QTL). The genetic architecture of quantitative traits is defined by the characteristics of these genes: their number, the magnitude of their effects, their positions in the genome and their interactions with each other. QTL analysis is a valuable tool for exploring genetic architecture, and highlighting regions of the genome that contribute to the variation of a trait within a population.
Lark
Karl G
KG
Department of Biology, University of Utah, Salt Lake City, UT 84112-0840, USA. lark@bioscience.utah.edu
Chase
Kevin
K
Sutter
Nathan B
NB
D000818:Animals; D001947:Breeding; D002874:Chromosome Mapping; D004285:Dogs / Q000033:anatomy & histology / Q000235:genetics*; D005260:Female; D014644:Genetic Variation; D015810:Linkage Disequilibrium; D008297:Male; D010641:Phenotype; D040641:Quantitative Trait Loci; D012727:Sex Characteristics