title: Assessing cortical functional connectivity by partial directed coherence: simulations and application to real data.
abstract: The aim of this paper is to test a technique called partial directed coherence (PDC) and its modification (squared PDC; sPDC) for the estimation of human cortical connectivity by means of simulation study, in which both PDC and sPDC were studied by analysis of variance. The statistical analysis performed returned that both PDC and sPDC are able to estimate correctly the imposed connectivity patterns when data exhibit a signal-to-noise ratio of at least 3 and a length of at least 27 s of nonconsecutive recordings at 250 Hz of sampling rate, equivalent, more generally, to 6750 data samples.
authors.affiliation: Dip Informatica e Sistemistica, Universita La Sapienza, Rome, Italy. laura.astolfi@uniromal.it
authors.forename: Laura
authors.initials: L
authors.lastname: Astolfi
authors.forename: Febo
authors.initials: F
authors.lastname: Cincotti
authors.forename: Donatella
authors.initials: D
authors.lastname: Mattia
authors.forename: M G
authors.initials: MG
authors.lastname: Marciani
authors.forename: Luis A
authors.initials: LA
authors.lastname: Baccalà
authors.forename: Fabrizio
authors.initials: F
authors.lastname: de Vico Fallani
authors.forename: Serenella
authors.initials: S
authors.lastname: Salinari
authors.forename: Mauro
authors.initials: M
authors.lastname: Ursino
authors.forename: Melissa
authors.initials: M
authors.lastname: Zavaglia
authors.forename: Fabio
authors.initials: F
authors.lastname: Babiloni
mesh_terms: D000465:Algorithms; D001931:Brain Mapping / Q000379:methods*; D002540:Cerebral Cortex / Q000502:physiology*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D019054:Evoked Potentials, Motor / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology