Diffuse lung cysts in lymphoid interstitial pneumonia: high-resolution CT and pathologic findings.
Lymphoid interstitial pneumonia is part of a spectrum of pulmonary lymphoproliferative disorders that range from benign, small, and airway-centered cellular infiltrates (follicular bronchiolitis, nodular lymphoid hyperplasia) to low-grade malignant lymphoma. Most of the cases occur in patients with underlying autoimmune disease or immunodeficiency. The characteristic high-resolution computed tomography findings consist of diffuse ground-glass opacities, ill-defined centrilobular nodules, bronchovascular thickening, interlobular septal thickening, and scattered thin-walled cysts. The cysts may be seen in up to 80% of the patients and are typically few in number and measure less than 3 cm in diameter. This case illustrates extensive cysts as the predominant high-resolution computed tomography finding of idiopathic lymphoid interstitial pneumonia in a 64-year-old man who underwent unilateral lung transplant. Such extensive cystic disease and lung transplantation treatment has not been previously described.
Silva
C Isabela S
CI
Department of Radiology, Vancouver General Hospital, University of British Columbia 899 West 12th Avenue, Vancouver, BC, Canada. isabela.silva@vch.ca
Flint
Julia D
JD
Levy
Robert D
RD
Müller
Nestor L
NL
D003560:Cysts / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D016040:Lung Transplantation; D008221:Lymphoid Tissue / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications / Q000473:pathology*; D014057:Tomography, X-Ray Computed