[Dendritic cells and transplantation immune tolerance--review].
Dendritic cells (DC) play an important roles in the maintenance of central immune tolerance and peripheral immune tolerance. DC can be involved in formation of autoimmune tolerance by many mechanisms and demonstrate strong plasticity, so that DC become hot issue in the research of transplantation tolerance recently. In this article the DC typing and its role, the indirect pathway of DC-inducing immune tolerance, the F1t3L and apoptotic cell role, the modified DC by genetic engineering and the immune inhibitors were summarized.
Zeng
Hui
H
Jiangsu Province Institute of Hematology, The First Affiliated Hospital, Suzhou Universily, Suzhou 215006, China.
He
Guang-Sheng
GS
Wu
De-Pei
DP
D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D023001:Transplantation Tolerance / Q000276:immunology*