title: Properties of novel and widely studied Y-STR loci in three South African populations.
abstract: The objective of the present study was to examine the properties of a set of single-copy Y-STR loci to assess their suitability for forensic casework in three South African populations. Three criteria were used to select markers for assessment. Firstly, the single-copy markers of the minimal haplotype were selected based on their established use in forensic studies. Secondly, 8 markers were selected on the basis of high gene diversity values reported for several population studies, and thirdly 19 markers were chosen from a survey of Y-chromosome sequence with selections made primarily on the basis of the number of repeated elements present. Samples were typed from 101 English-speaking Caucasians, 88 Xhosa individuals and 77 Asian Indians. Gene diversity values, the number of alleles identified and the average stutter was determined for each locus.
authors.affiliation: Biotechnology Department, University of the Western Cape, Private Bag X17, Bellville, 7535 Cape Town, South Africa. nleat@uwc.ac.za
authors.forename: Neil
authors.initials: N
authors.lastname: Leat
authors.forename: Liezle
authors.initials: L
authors.lastname: Ehrenreich
authors.forename: Mongi
authors.initials: M
authors.lastname: Benjeddou
authors.forename: Kevin
authors.initials: K
authors.lastname: Cloete
authors.forename: Sean
authors.initials: S
authors.lastname: Davison
mesh_terms: D044466:Asian People / Q000235:genetics*; D044383:Black People / Q000235:genetics*; D041322:Chromosomes, Human, Y / Q000235:genetics*; D053803:Forensic Genetics / Q000379:methods; D005787:Gene Frequency / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D013019:South Africa; D044465:White People / Q000235:genetics*
chemical_list: D005819:Genetic Markers