Estrogen therapy and cognition: a 6-year single-blind follow-up study in postmenopausal women.
The authors evaluated the effect of long-term hormone therapy (HT) on cognition in 60 postmenopausal women (aged 53 to 72 years) in a single-blind, 6-year follow-up study. The subjects were divided into three groups: non-HT users, continuous HT users, and irregular HT users. Measures of verbal and visuomotor skills, verbal and visual memory, and attention were used. All women had well-maintained cognitive performance. Long-term HT did not affect cognition, either for better or for worse.
Alhola
Paula
P
Department of Psychology, Sleep Research Unit, University of Turku, Turku, Finland. paula.alhola@utu.fi
Polo-Kantola
Päivi
P
Erkkola
Risto
R
Portin
Raija
R
D003071:Cognition / Q000187:drug effects*; D003072:Cognition Disorders / Q000453:epidemiology*; D018592:Cross-Over Studies; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D020249:Hormone Replacement Therapy / Q000706:statistics & numerical data*; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016037:Single-Blind Method
D004967:Estrogens