Frequency-domain wide-field laser Doppler in vivo imaging.
We present a new instrument, based on a low-frame-rate (8 Hz) CCD camera used in a heterodyne optical-mixing configuration, that can create wide-field laser Doppler maps. As an illustration, we show results obtained in a mouse brain, in vivo, showing the Doppler signature of blood flow. The instrument is based on a frequency-shifting digital holography scheme.
Atlan
M
M
Laboratoire Kastler-Brossel, UMR 8552, Ecole Normale Supérieure, Paris Cedex, France. atlan@lkb.ens.fr
Gross
M
M
Forget
B C
BC
Vitalis
T
T
Rancillac
A
A
Dunn
A K
AK
D000818:Animals; D017078:Laser-Doppler Flowmetry; D007834:Lasers; D051379:Mice; D008810:Mice, Inbred C57BL; D012039:Regional Blood Flow; D012542:Scattering, Radiation; D012886:Skull / Q000098:blood supply*