Differences in mitotic activity may explain observed differences in HIF-1alpha response in cancers and stroma.
Mittal
Khush
K
D015687:Cell Hypoxia / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000378:metabolism*; D008938:Mitosis / Q000502:physiology*; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D017154:Stromal Cells / Q000378:metabolism*
D051795:Hypoxia-Inducible Factor 1, alpha Subunit