title: Relief of acute migraine headache with intravenous oxytocin: report of two cases.
abstract: We present 2 cases, one adult and one pediatric, of acute migraine headache promptly relieved by intravenous oxytocin. Both cases were typical flares of a chronic intermittent headache pattern with classic vascular symptoms. Pain relief in both cases was rapid and temporally related to oxytocin administration. Vascular headache pathophysiology and possible oxytocin mechanisms of action are discussed.
authors.affiliation: Department of Emergency Medicine, University of Mississippi Medical Center, 2500 North State St, Jackson, MS 39216, USA. wphillips@emergmed.umsmed.edu
authors.forename: William J
authors.initials: WJ
authors.lastname: Phillips
authors.forename: Olga
authors.initials: O
authors.lastname: Ostrovsky
authors.forename: Robert L
authors.initials: RL
authors.lastname: Galli
authors.forename: Sharon
authors.initials: S
authors.lastname: Dickey
mesh_terms: D000208:Acute Disease; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D007276:Injections, Intraventricular; D008297:Male; D008881:Migraine Disorders / Q000188:drug therapy*; D010121:Oxytocin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000700:Analgesics; D010121:Oxytocin