title: Acellular dermal matrix as an adjunct in treatment of neuropathic pain at the wrist.
abstract: BACKGROUND
  Traumatic or surgical injury to superficial sensory nerves at the wrist can lead to significant morbidity. Multiple treatment modalities have been proposed, including the use of flap coverage to provide soft-tissue padding and decrease tactile irritation. In this report, acellular dermal matrix (AlloDerm) was used as an alternative to flap coverage, thereby avoiding the need for a donor site.
  
  
  METHODS
  Five patients with postsurgical and five patients with posttraumatic neuropathic pain at the wrist underwent neuroma excision and/or neurolysis followed by interposition of acellular dermal matrix allograft between skin and nerve.
  
  
  RESULTS
  Patients were followed from 12 to 25 months and demonstrated substantial improvement in pain. Eight previously employed patients returned to their prior occupations.
  
  
  CONCLUSIONS
  Dermal matrix allograft may provide cushioning and/or a gliding surface for the nerve and represents a simple alternative to flap coverage in the treatment of neuropathic pain at the wrist.
authors.affiliation: Hand Surgery Section, Department of Orthopedics and Rehabilitation, and Division of Plastic Surgery, University of Oklahoma Medical Center, Oklahoma City, Oklahoma, USA. steve.peterson@dhha.org
authors.forename: Steven L
authors.initials: SL
authors.lastname: Peterson
authors.forename: Mehdi N
authors.initials: MN
authors.lastname: Adham
mesh_terms: D000328:Adult; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods*; D017768:Skin, Artificial; D016896:Treatment Outcome; D014954:Wrist Injuries / Q000601:surgery*
chemical_list: C440568:Alloderm; D003094:Collagen