Mucormycosis resulting in gastric perforation in a patient with acute myelogenous leukemia: report of a case.
Mucormycosis is an uncommon opportunistic fungal infection that may develop in immunocompromised patients with conditions such as diabetes mellitus, leukemia, lymphoma, or human immunodeficiency virus (HIV), or after transplantation with immunosupperessive therapy. We report a case of gastric perforation caused by a mucormycosis infection in a patient with acute myelogenous leukemia (AML). The patient was treated successfully with gastrectomy and the aggressive use of intravenous amphotericin B. He is still alive 1 year after his operation.
Song
Kyo Young
KY
Department of Surgery, The Catholic University of Korea, Seoul, Korea.
Kang
Won Kyung
WK
Park
Chong Won
CW
Choi
Yeong Jin
YJ
Rha
Sung Eun
SE
Park
Cho Hyun
CH
D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D016867:Immunocompromised Host; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications*; D013270:Stomach / Q000293:injuries* / Q000382:microbiology; D016896:Treatment Outcome
D000935:Antifungal Agents; D000666:Amphotericin B