title: Activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen scaffold.
abstract: We investigated the effect of gamma-irradiation on the activities of MC3T3-E1 cells cultured on gamma-irradiated salmon atelocollagen (SAC) scaffolds. SAC-cultured samples were irradiated at doses of 10, 15, and 25 kGy. Gamma-irradiation had a significant impact on the activities of MC3T3-E1 cells. The proliferation rates and alkaline phosphatase activities of MC3T3-E1 cells increased with gamma-irradiation dose.
authors.affiliation: Creative Research Initiative Sousei, Hokkaido University, N21-W10, Sapporo, Hokkaido 001-0021, Japan. nagai@cris.hokudai.ac.jp
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Nagai
authors.forename: Takafumi
authors.initials: T
authors.lastname: Anzawa
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Satoh
authors.forename: Takeshi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kenji
authors.initials: K
authors.lastname: Tajima
authors.forename: Masanobu
authors.initials: M
authors.lastname: Munekata
mesh_terms: D016475:3T3 Cells; D000818:Animals; D018929:Cell Culture Techniques / Q000379:methods*; D049109:Cell Proliferation / Q000528:radiation effects*; D002470:Cell Survival / Q000528:radiation effects*; D003094:Collagen / Q000378:metabolism* / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D051379:Mice; D011829:Radiation Dosage; D012474:Salmon / Q000378:metabolism*
chemical_list: C059821:atelocollagen; D003094:Collagen