The multidimensionality of cell behaviors underlying morphogenesis: a case study in ascidians.
Databases where different types of information from different sources can be integrated, cross-referenced and interactively accessed are necessary for building a quantitative understanding of the molecular and cell biology intrinsic to the morphogenesis of an embryo. Tassy and colleagues recently reported the development of software tailor-made to perform such a task, along with the generation and integration of three-dimensional anatomical models of embryos. They convincingly illustrated the utility of their approach by applying it to the early ascidian embryo.
Di Gregorio
Anna
A
Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10021, USA.
Hadjantonakis
Anna-Katerina
AK
D000818:Animals; D005075:Biological Evolution; D002470:Cell Survival; D002938:Ciona intestinalis / Q000166:cytology* / Q000196:embryology*; D030541:Databases, Genetic; D004625:Embryo, Nonmammalian / Q000166:cytology* / Q000196:embryology*; D015870:Gene Expression; D009024:Morphogenesis