Heart and respiration rate changes in the neonate during electroencephalographic seizure.
An investigation of changes in the neonatal electrocardiogram (ECG) and respiration signals from labelled seizure data for five neonatal patient records is reported. A decrease during seizure of 5.70% in the mean RR-interval was found. The mean respiration rate per epoch was found to decrease by a mean 18.44% during seizure. No significant change in the RR-interval standard deviation or in the mean respiration amplitude during seizure was observed. These results raise the possibility of using ECG and respiration based methods instead of existing electrcoenceplogram (EEG) based methods, or in concert with EEG-based neonatal seizure detection methods to improve on previously reported seizure detection methods.
Greene
Barry R
BR
School of Electrical, Electronic and Mechanical Engineering, University College Dublin, Dublin, Ireland. barry.greene@ee.ucd.ie
de Chazal
Philip
P
Boylan
Geraldine
G
Reilly
Richard B
RB
O'Brien
Ciara
C
Connolly
Sean
S
D000704:Analysis of Variance; D004562:Electrocardiography; D004569:Electroencephalography; D001330:Electronic Data Processing; D020936:Epilepsy, Benign Neonatal / Q000175:diagnosis* / Q000503:physiopathology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D015656:Respiratory Mechanics; D012815:Signal Processing, Computer-Assisted