title: Successful treatment of visceral leishmaniasis with liposomal amphotericin B.
abstract: We report a case of a 26-year-old female from Kenya who suffered from intermittent fever of unknown origin for one month. The major findings on admission were pancytopenia associated with considerable splenomegaly. The diagnosis was established by visualisation of amastigotes in bone marrow biopsy and by detection of antibodies to Leishmania spp. in blood. The infection was treated intravenously with liposomal amphotericin B for five days. The patient was afebrile after the first infusion. No relapse was reported.
authors.affiliation: Department of Internal Medicine I, Division of Infectious Diseases and Chemotherapy, Medical University of Vienna, Austria.
authors.forename: Heimo
authors.initials: H
authors.lastname: Lagler
authors.forename: Ulrich
authors.initials: U
authors.lastname: Matt
authors.forename: Christian
authors.initials: C
authors.lastname: Sillaber
authors.forename: Stefan
authors.initials: S
authors.lastname: Winkler
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Graninger
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001317:Austria; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D007630:Kenya / Q000208:ethnology; D007898:Leishmaniasis, Visceral / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008081:Liposomes; D012074:Remission Induction
chemical_list: D000981:Antiprotozoal Agents; D008081:Liposomes; C068538:liposomal amphotericin B; D000666:Amphotericin B