[Mantle-cell lymphoma of the ocular adnexa: a case report].
Ocular adnexal lymphoid tumors are slow-growing neoplasms that affect predominantly the elderly. The purpose of this study is to report a non-Hodgkin lymphoma from mantle zone cells, a rare ocular annexal B-cell lymphoma subtype.


METHODS
A 62-year-old male patient with superior eyelid, maxillary and oral tumours, had an initial diagnosis of Mikulics disease, developed lesion enlargement, despite immunosuppressant therapy. Left superior eyelid and bone marrow biopsy revealed non-Hodgkin lymphoma the mantle zone. In spite of dissemination (stage IV), chemotherapy and bone marrow transplant led to disease remission.
Despite the availability of advanced complementary diagnostic methods, like immunophenotyping and molecular genetic analysis, lymphoma represents, for physicians and pathologists, a challenge regarding diagnosis and prognosis.
de Albuquerque
Anna Paula Lemos
AP
Departamento de Plástica Ocular, Dr. Homero de Miranda Gomes Hospital Regional de São José, São José, SC, Brazil.
Aguni
Jonathan Seiji
JS
Correia
Renato José Bett
RJ
Vegini
Franciele
F
de Souza
André Dalsasso Borges
AD
D000971:Antineoplastic Combined Chemotherapy Protocols; D001706:Biopsy; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome