[Ghrelin - a novel appetite-stimulating hormone which also affects gastrointestinal functions].
Ghrelin, a novel gastrointestinal peptide with 28 amino acids, is secreted from the A-like cells of the gastric fundus. This peptide hormone does not only promote the release of growth hormone, but also stimulates food intake, gastric motility and cardiac output. Increased plasma ghrelin level has been reported in patients with upper gastrointestinal (GI) disease or in their disease animal model, suggesting its important role in the pathogenesis of upper GI disease.
Suzuki
Hidekazu
H
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. hsuzuki@sc.itc.keio.ac.jp
Masaoka
Tatsuhiro
T
Hibi
Toshifumi
T
D001066:Appetite / Q000502:physiology*; D003543:Cysteamine / Q000378:metabolism; D004415:Dyspepsia / Q000209:etiology; D004435:Eating; D005767:Gastrointestinal Diseases / Q000209:etiology*; D054439:Ghrelin / Q000502:physiology*; D006801:Humans; D010437:Peptic Ulcer / Q000209:etiology
D054439:Ghrelin; D003543:Cysteamine