Weakness is the primary contributor to finger impairment in chronic stroke.
OBJECTIVE
To assess the relative contributions of several neurologic and biomechanic impairment mechanisms to overall finger and hand impairment in chronic hemiparetic stroke survivors.


METHODS
Repeated-measures design.


METHODS
Clinical research laboratory.


METHODS
Thirty stroke survivors with chronic hemiparesis. Fifteen subjects had severe hand motor impairment and 15 had moderate impairment, as measured with the Chedoke-McMaster Stroke Assessment.


METHODS
Not applicable.


METHODS
The biomechanic factors stiffness and resting flexion torque, together with the neurologic factors spasticity, strength, and coactivation, were quantified by using a custom hand manipulator, a dynamometer, and electromyographic recordings. Both passive and active rotations of the metacarpophalangeal joints of the fingers were examined.


RESULTS
Although subjects in the severely impaired group exhibited statistically greater passive stiffness and resting flexion torque than their moderately impaired counterparts (P<.05), the overall effect of these biomechanic changes appeared small in relation to the deficits attributable to neurologic changes such as spasticity and, especially, weakness. In fact, weakness in grip strength and isometric extension accounted for the greatest portion of the variance between the 2 groups (eta(2)=.40 and eta(2)=.23, respectively).


CONCLUSIONS
Thus, deficits in hand motor control after stroke seem to derive mainly from weakness, which may be attributable to the loss of descending corticospinal pathway activation of motoneurons.
Kamper
Derek G
DG
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL 606011, USA. d-kamper@northwestern.edu
Fischer
Heidi C
HC
Cruz
Erik G
EG
Rymer
William Z
WZ
D001696:Biomechanical Phenomena; D002908:Chronic Disease; D004576:Electromyography; D005385:Fingers; D018737:Hand Strength; D006801:Humans; D008875:Middle Aged; D018908:Muscle Weakness / Q000145:classification / Q000209:etiology*; D012720:Severity of Illness Index; D020521:Stroke / Q000145:classification / Q000503:physiopathology*