title: Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature.
abstract: Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 year later a gastric recurrence of RCC treated 10 years ago with a resection and interleukin-2 (IL-2). Accumulating evidence indicates that metastatic involvement of the pancreas and stomach should be suspected in any patient with a history of RCC who presents with gastrointestinal symptoms even 10 years after RCC resection and immunotherapy.
authors.affiliation: Second Division of General and Vascular Surgery, Careggi Hospital, Florence, Italy. chiarariviello@libero.it
authors.forename: Chiara
authors.initials: C
authors.lastname: Riviello
authors.forename: Ilaria
authors.initials: I
authors.lastname: Tanini
authors.forename: Greta
authors.initials: G
authors.lastname: Cipriani
authors.forename: Pietro
authors.initials: P
authors.lastname: Pantaleo
authors.forename: Carlo
authors.initials: C
authors.lastname: Nozzoli
authors.forename: Alberto
authors.initials: A
authors.lastname: Poma
authors.forename: Viligiardi
authors.initials: V
authors.lastname: Riccardo
authors.forename: Andrea
authors.initials: A
authors.lastname: Valeri
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy; D007376:Interleukin-2 / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy*; D008297:Male; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000556:secondary; D012008:Recurrence; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000556:secondary
chemical_list: D007376:Interleukin-2