title: Probing fast kinetics in complex fluids by combined rapid mixing and small-angle X-ray scattering.
abstract: Stopped-flow mixing coupled to small-angle X-ray scattering (SAXS) is an established technique for investigating structural kinetics in solution down to the millisecond range. More recently, the emphasis has shifted to the sub-millisecond range using continuous flow microfluidic mixing devices. The aim of this article is to review the present status and limitations when applying mixing techniques to a wide range of soft matter and biological systems. In the case of SAXS, special consideration of the mixing quality is necessary for a quantitative description of the scattered intensity. This is demonstrated through two representative examples involving protein refolding and micellar self-assembly.
authors.affiliation: European Synchrotron Radiation Facility, F-38043 Grenoble, France. panine@esrf.fr
authors.forename: P
authors.initials: P
authors.lastname: Panine
authors.forename: S
authors.initials: S
authors.lastname: Finet
authors.forename: T M
authors.initials: TM
authors.lastname: Weiss
authors.forename: T
authors.initials: T
authors.lastname: Narayanan