Cell shape in proliferating epithelia: a multifaceted problem.
A specific and unexpected distribution pattern of polygonal cell shapes in proliferating epithelia is revealed in a recent study that combines mathematical modeling with experimental data (Gibson et. al., 2006). This pattern is conserved in epithelia from diverse species, suggesting that this distribution is a fundamental property of proliferating epithelial sheets.
Axelrod
Jeffrey D
JD
Department of Pathology, Stanford University School of Medicine, CA 94305, USA. jaxelrod@stanford.edu
D000818:Animals; D049109:Cell Proliferation; D048430:Cell Shape; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000196:embryology; D004847:Epithelial Cells / Q000166:cytology* / Q000378:metabolism; D008433:Mathematics; D008962:Models, Theoretical