Effects of oxcarbazepine on cognitive function in children and adolescents with partial seizures.
The authors investigated the effect of oxcarbazepine on cognitive function in children and adolescents (6 to younger than 17 years of age) with newly diagnosed partial seizures in an open-label comparison with standard antiepileptic drug therapy (carbamazepine and valproate). No differences in cognitive tests were observed between oxcarbazepine and carbamazepine/valproate over a 6-month treatment period.
Donati
F
F
Neurologie, Spitalzentrum Biel, University Hospital, Bern, Switzerland.
Gobbi
G
G
Campistol
J
J
Rapatz
G
G
Daehler
M
M
Sturm
Y
Y
Aldenkamp
A P
AP
D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage; D002220:Carbamazepine / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D002648:Child; D003071:Cognition / Q000187:drug effects*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D004338:Drug Combinations; D004828:Epilepsies, Partial / Q000188:drug therapy* / Q000453:epidemiology*; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D000078330:Oxcarbazepine; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D016896:Treatment Outcome; D014635:Valproic Acid / Q000008:administration & dosage*
D000927:Anticonvulsants; D004338:Drug Combinations; D002220:Carbamazepine; D014635:Valproic Acid; D000078330:Oxcarbazepine