The high-resolution chest CT findings in an adult with Melnick-Needles syndrome.
Melnick-Needles syndrome is an X-linked dominant skeletal dysplasia in which patients often succumb at an early age to chronic pulmonary disease. Radiographic findings of Melnick-Needles syndrome consist of characteristic bony abnormalities and interstitial lung disease. We present the high-resolution computed tomographic (CT) findings in a 39-year-old survivor of Melnick-Needles syndrome. The clinical and physical exam findings also demonstrate an association between Melnick-Needles syndrome and obstructive sleep apnea.
Harper
Derrick
D
Department of Radiology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Bloom
David A
DA
Rowley
James A
JA
Soubani
Ayman
A
Smith
Wilbur L
WL
D000328:Adult; D005260:Female; D040181:Genetic Diseases, X-Linked / Q000175:diagnosis*; D006801:Humans; D010009:Osteochondrodysplasias / Q000150:complications / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic; D012129:Respiratory Function Tests; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed