title: Concurrence of Sjögren's syndrome in a patient with Chlamydia-induced reactive arthritis; an unusual finding.
abstract: A 40-year-old Korean man presented with painful swelling and tenderness of both ankle joints as well as the plantar surfaces of both feet, along with inflammatory back pain, and a purulent discharge from the urethral orifice. The patient also complained of sicca-like symptoms including dry eyes and dry mouth. An immunological analysis revealed a high titer of rheumatoid factor, positive results for antinuclear antibody and anti-Ro antibody, and a positive result for HLA-B27. An antibody titer for Chlamydia was also significantly increased. Positive results of the Schirmer's test and for keratoconjunctivitis sicca were confirmed by an ophthalmologist. These clinical manifestations were compatible with Chlamydia-induced reactive arthritis (ReA) accompanied by Sjögren's syndrome (SS). This is the first report of the combination of these two distinct disease entities in the Korean population.
authors.affiliation: Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea.
authors.forename: Hyun Kyu
authors.initials: HK
authors.lastname: Chang
authors.forename: Ki Tae
authors.initials: KT
authors.lastname: Bang
authors.forename: Bo Han
authors.initials: BH
authors.lastname: Lee
authors.forename: Jung Hyuk
authors.initials: JH
authors.lastname: Kim
authors.forename: Kang Woo
authors.initials: KW
authors.lastname: Bae
authors.forename: Myong Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Seong-Kyu
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D016918:Arthritis, Reactive / Q000150:complications*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis; D006801:Humans; D008297:Male; D000091402:Prohibitins; D012859:Sjogren's Syndrome / Q000150:complications*
chemical_list: D000974:Antibodies, Antinuclear; C000717331:PHB2 protein, human; D000091402:Prohibitins