title: Genomic ancestry of a sample population from the state of São Paulo, Brazil.
abstract: Allelic frequencies of eight autosomal short-tandem repeat (STR) loci (TH01, TPOx, CSF1PO, vWA, FES/FPS, F13A1, F13B, and CD4) were determined in 400 individuals born in the State of São Paulo. No significant deviations from Hardy-Weinberg equilibrium were found in any loci analyzed. The Unweighted Pair-Group Method with Arithmetic Mean (UPGMA) tree constructed based on genetic distances revealed that the present population was grouped with Europeans, and separated from African and Amerindian populations. Estimates of admixture components based on the gene identity method revealed 79% European, 14% African, and 7% Amerindian contributions to this Brazilian population sample.
authors.affiliation: Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, 14049-900 Ribeirão Preto, São Paulo, Brazil.
authors.forename: Luzitano Brandão
authors.initials: LB
authors.lastname: Ferreira
authors.forename: Celso Teixeira
authors.initials: CT
authors.lastname: Mendes-Junior
authors.forename: Cláudia Emília Vieira
authors.initials: CE
authors.lastname: Wiezel
authors.forename: Marcelo Rizzatti
authors.initials: MR
authors.lastname: Luizon
authors.forename: Aguinaldo Luiz
authors.initials: AL
authors.lastname: Simões
mesh_terms: D001938:Brazil; D005260:Female; D005828:Genetics, Population / Q000379:methods; D006801:Humans; D008297:Male; D040641:Quantitative Trait Loci / Q000235:genetics*; D044469:Racial Groups / Q000235:genetics*; D020080:Tandem Repeat Sequences / Q000235:genetics*