title: Diagnosis of thoracic splenosis by ferumoxides-enhanced magnetic resonance imaging.
abstract: We report on a 56-year-old woman with a history of splenectomy and surgery of the left hemidiaphragm, who presented with multiple pleural and mediastinal mass lesions. On the basis of the patient's history of splenectomy and missing Howell-Jolly bodies in peripheral blood smears, splenosis was suspected. To confirm the presumptive diagnosis, ferumoxides-enhanced magnetic resonance was performed. As all lesions showed a pronounced signal loss on T2* sequences, the diagnosis of splenosis was made and was further confirmed by scintigraphy. The reported case illustrates that ferumoxides-enhanced magnetic resonance imaging may be a helpful tool for the evaluation of suspected splenosis.
authors.affiliation: Department of Radiology, Otto Wagner Hospital, Vienna, Austria.
authors.forename: Helmut
authors.initials: H
authors.lastname: Prosch
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Oschatz
authors.forename: Esther
authors.initials: E
authors.lastname: Pertusini
authors.forename: Gerhard
authors.initials: G
authors.lastname: Mostbeck
mesh_terms: D003287:Contrast Media; D003911:Dextrans; D005260:Female; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles; D008875:Middle Aged; D010087:Oxides; D011856:Radiographic Image Enhancement; D011877:Radionuclide Imaging; D017890:Splenosis / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide