Disseminated Langerhans cell histiocytosis-an interesting case report with concise review of literature.
A 2-year-old boy presented with fever, recurrent infections and multiple skin lesions. He had anemia, eczematous skin lesions, cervical lymph node enlargement, hepatomegaly and lytic lesions on skull x-ray. The skin infiltrates were CD 68, CD 1a positive and S100 positive. He was diagnosed as disseminated langerhans cell histiocytosis. The occurrence of histiocytosis is reviewed and possible treatment is discussed.
Chatterjee
T
T
Department of Hematology, AIIMS, New Delhi.
Naithani
Rahul
R
Agrawal
Neerja
N
Bhattacharya
Jina
J
Bhattacharya
Maitraii
M
Dutta
P
P
Pati
H P
HP
Mahapatra
M
M
Choudhary
V P
VP
D015703:Antigens, CD / Q000378:metabolism; D018949:Antigens, CD1 / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D002675:Child, Preschool; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009418:S100 Proteins / Q000378:metabolism; D000097382:CD68 Molecule
D015703:Antigens, CD; D018949:Antigens, CD1; D015214:Antigens, Differentiation, Myelomonocytic; D009418:S100 Proteins; C419393:CD1a antigen; C067980:CD68 antigen, human; D000097382:CD68 Molecule