Adding spironolactone to conventional antihypertensives reduces albuminuria in patients with diabetic nephropathy.
Epstein
Murray
M
University of Miami School of Medicine, Miami, FL, USA. murraye@gate.net
D000328:Adult; D000450:Aldosterone / Q000097:blood; D018592:Cross-Over Studies; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D000451:Mineralocorticoid Receptor Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D013148:Spironolactone / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D000450:Aldosterone