Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups.
Kurosaki
Hiromasa
H
Department of Structure-function Physical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University Oe-honmachi 5-1, Kumamoto, Japan.
Yamaguchi
Yoshihiro
Y
Yasuzawa
Hisami
H
Jin
Wanchun
W
Yamagata
Yuriko
Y
Arakawa
Yoshichika
Y
D018360:Crystallography, X-Ray; D003619:Dansyl Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D007202:Indicators and Reagents; D008958:Models, Molecular; D012706:Serratia marcescens / Q000187:drug effects / Q000201:enzymology; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases / Q000737:chemistry*
D003619:Dansyl Compounds; D004791:Enzyme Inhibitors; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D013438:Sulfhydryl Compounds; D065093:beta-Lactamase Inhibitors; C409201:beta-lactamase IMP-1; D001618:beta-Lactamases