title: Antibiotic-impregnated PMMA hip spacers: Current status.
abstract: The infection rate after primary hip arthroplasty lies at 1-2%. In the past few years, a two-stage protocol with the implantation of an antibiotic-loaded spacer has become a popular procedure in the treatment of infected hip joint arthroplasties. In this review, we pay special attention to the elution characteristics of the spacers, their mechanical stability and the clinical response. We conclude that hip spacers are an effective method in the treatment of hip joint infections, with success rates of over 90%.
authors.affiliation: Klinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes. Homburg/Saar. Germany. konstantinos.anagnostakos@iniklinik-saarland.de
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Anagnostakos
authors.forename: Oliver
authors.initials: O
authors.lastname: Fürst
authors.forename: Jens
authors.initials: J
authors.lastname: Kelm
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001696:Biomechanical Phenomena; D001843:Bone Cements; D004338:Drug Combinations; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D019904:Polymethyl Methacrylate; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D004338:Drug Combinations; D019904:Polymethyl Methacrylate