title: Oxocyclostylidol, an intramolecular cyclized oroidin derivative from the marine sponge Stylissa caribica.
abstract: Pyrrole-imidazole alkaloids are widely distributed in marine sponges of the orders Halichondrida and Agelasida. Chemical investigation of the Caribbean sponge Stylissa caribica has led to the isolation of the first brominated pyrrole-imidazole alkaloid containing an oxidized pyrrole moiety. The isolation and structure elucidation of oxocyclostylidol (1) are discussed in detail.
authors.affiliation: Alfred-Wegener-Institut für Polar- und Meeresforschung in der Helmholtz-Gemeinschaft, Am Handelshafen 12, D-27570 Bremerhaven, Germany.
authors.forename: Achim
authors.initials: A
authors.lastname: Grube
authors.forename: Matthias
authors.initials: M
authors.lastname: Köck
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D000818:Animals; D017691:Caribbean Region; D003500:Cyclization; D008386:Marine Biology; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D000470:Alkaloids; D011758:Pyrroles; C513772:oxocyclostylidol; C077209:oroidin