[Transient left ventricular apical ballooning syndrome or Takotsubo cardiomyopathy. About 11 cases].
Takotsubo cardiomyopathy is a clinical entity mimicking an ST elevation myocardial infarction recently identified. Are associated a chest pain, electrocardiographics abnormalities, minor elevation of enzyme biomarkers in patients who don't have any significant angiographic stenosis on the coronary angiography and where left ventricle angiography shows apical regional wallmotion abnormalities with a characteristic apical ballooning aspect. Between march 2003 and march 2005, we included 11 patients for whom this syndrom was suspected. Mean age was 70, 3 years old. Electrocardiogram was abnormal in all cases. Biological markers show for all patients an elevation of troponin I. All patients had a coronary angiography and coronary arteries were normal. Left ventricle angiography showed in all cases wall-motion abnormalities in the apex with a ballooning aspect. A psychological or physical inducing factor has been found for 8 patients. The evolution was simple for all patients with no complications noted and no recurrence with a mean follow up of 15 months. Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrom have a good long-term prognosis even if serious complications sometimes deathly can be seen. The cause of this syndrom is unknown but it must be considered as a possible diagnosis of ST elevation myocardial infarction with normal coronary arteries.
El Mahmoud
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Service de cardiologie, CHI Le-Raincy-Montfermeil, 10, rue du général-Leclerc, 93370 Montfermeil, France. emrami@yahoo.fr
Leyer
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Michaud
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Nallet
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Cattan
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D000368:Aged; D000369:Aged, 80 and over; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000473:pathology*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis; D013577:Syndrome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000473:pathology*