Myocardial 15-epi-lipoxin A4 generation provides a new mechanism for the immunomodulatory effects of statins and thiazolidinediones.
Levy
Bruce D
BD
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D007155:Immunologic Factors / Q000494:pharmacology*; D044045:Lipoxins / Q000096:biosynthesis*; D008954:Models, Biological; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D045162:Thiazolidinediones / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007155:Immunologic Factors; D044045:Lipoxins; D045162:Thiazolidinediones; C040527:lipoxin A4