title: Hepatic focal nodular hyperplasia developing in a Fanconi anemia patient: a case report and literature review.
abstract: Fanconi anemia, an autosomal recessive and X-linked disorder, is known to be associated with a variety of neoplasms. Liver tumors are one of the most frequently observed neoplasms but the association between the two disorders remains obscure. We present a case of a 27-year old female Fanconi anemia patient diagnosed with a mass on the right lobe of the liver measuring 90x75x60 mm. Histopathological examination of the mass after right hepatic lobectomy revealed focal nodular hyperplasia. This appears to be the first reported case of a hepatic focal nodular hyperplasia of such proportion associated with Fanconi anemia. Previously reported cases of liver tumors in association with Fanconi anemia in the English Literature were either hepatocellular carcinomas or hepatic adenomas.
authors.affiliation: Hacettepe University School Of Medicine, Department of General Surgery, Sihhiye, Ankara 06100 Turkey. Drnuamah@Yahoo.Com
authors.forename: Nabil M
authors.initials: NM
authors.lastname: Nuamah
authors.forename: Erhan
authors.initials: E
authors.lastname: Hamaloglu
authors.forename: Arif
authors.initials: A
authors.lastname: Ozdemir
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ozenc
authors.forename: Chava
authors.initials: C
authors.lastname: Sozseker
authors.forename: Cenk
authors.initials: C
authors.lastname: Sokmensuer
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000209:etiology / Q000601:surgery; D005199:Fanconi Anemia / Q000150:complications*; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000601:surgery; D012196:Review Literature as Topic