title: Olefination of ketones using a gold(III)-catalyzed Meyer-Schuster rearrangement.
abstract: An atom-economical and efficient olefination strategy for ketones is described. Ethoxyacetylide addition followed by a gold-catalyzed Meyer-Schuster rearrangement affords alpha,beta-unsaturated esters, generally in excellent overall yield from the starting ketones. The alkynophilicity of Au3+ promotes an interaction with the electron-rich acetylenes that catalyzes the Meyer-Schuster rearrangement selectively over other conceivable pathways.
authors.affiliation: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Engel
authors.forename: Gregory B
authors.initials: GB
authors.lastname: Dudley