title: Undifferentiated carcinoma of the submandibular salivary gland with fulminant clinical course: a case report.
abstract: Undifferentiated carcinoma of salivary glands is too poorly differentiated to be classified as any of the specific group of carcinomas. This is a rare disease, the incidence of which is rather low-to-very low in the Indian subcontinent. The tumor can assume an aggressive clinical behavior characterized by disseminated metastases. The prognosis is rated as dismal; as evidenced by this clinical report of a tumor in the submandibular salivary gland with synchronous metastases to the skull bones and in to the intracranial fossa. The putative relationship of the tumor to Epstein-Barr virus (EBV) infection is discussed.
authors.affiliation: Department of Oral Pathology, Govt. Dental College, Trivandrum, Kerala. rrajendran_r@yahoo.co.in
authors.forename: R
authors.initials: R
authors.lastname: Rajendran
authors.lastname: Vidyarani
authors.forename: P Bindu
authors.initials: PB
authors.lastname: Nair
authors.forename: Suresh C
authors.initials: SC
authors.lastname: Dutt
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary; D002277:Carcinoma / Q000209:etiology / Q000473:pathology* / Q000556:secondary; D020031:Epstein-Barr Virus Infections / Q000150:complications; D005260:Female; D006801:Humans; D012888:Skull Neoplasms / Q000556:secondary; D013365:Submandibular Gland Neoplasms / Q000209:etiology / Q000473:pathology*