Olanzapine for recurrent excessive irritability and psychotic symptoms after mesial temporal lobectomy in a patient with temporal lobe epilepsy.
We report the case of a patient with temporal lobe epilepsy, nonresponsive to antiepileptic drugs, who became seizure-free, but developed recurrent excessive irritability and psychotic symptoms after successful mesial temporal lobectomy. This patient was refractory to various pharmacological treatments including antipsychotics, mood stabilizers, and benzodiazepines before being successfully treated with olanzapine.
das Neves
Maila de Castro Lourenço
MC
Department of Psychiatry, Raul Soares Institute, Belo Horizonte, Brazil.
Mendes
Mirian Fabíola Studart Gurgel
MF
de Oliveira
Andréa Julião
AJ
Viana
Erika Machado
EM
de Guadalupe
Aila
A
de Barros
Hélio Lauar
HL
Hallak
Jaime Eduardo Cecílio
JE
Siqueira
José Maurício
JM
Salgado
João Vinícius
JV
D000328:Adult; D038481:Anterior Temporal Lobectomy; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology; D000077152:Olanzapine; D011183:Postoperative Complications / Q000188:drug therapy*
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine