title: [Development of a nitric oxide inhaling equipment cooperated with the ventilator synchronously].
abstract: A nitric oxide inhaling equipment cooperated with the ventilator synchronously, is introduced in this paper. This equipment monitors the inspiratory flow of the ventilator by a gas flow meter, and works out the flow value of NO on the therapeutic condition using the formula of gas dilution. Then its mass flow controller controls the flow of NO and delivers it to the respiratory circuit. At the same time, the concentrations of NO and NO2 are detected by the electrochemical NO/NO2 sensors before the therapeutic gas enters into the patient. The experimental result shows that this equipment can work with the ventilator in-phase periodically, the volume of E/(I+E) NO be saved, and the output of NO2 < or = 0.7 x 10(-6). Thus the equipment not only has realized the intellectual monitoring and gas-dispensing, but also has improved the precision of inhaled NO concentration with a better reliability and security during the therapy.
authors.affiliation: General Hospital of Guangzhou Unit of the PLA.
authors.forename: Hong-tao
authors.initials: HT
authors.lastname: Zhang
authors.forename: Zhong-min
authors.initials: ZM
authors.lastname: Liu
authors.forename: Xue-feng
authors.initials: XF
authors.lastname: Zhu
mesh_terms: D004867:Equipment Design; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D008991:Monitoring, Physiologic / Q000379:methods; D009569:Nitric Oxide / Q000008:administration & dosage* / Q000032:analysis; D009585:Nitrogen Dioxide / Q000008:administration & dosage / Q000032:analysis; D012138:Respiratory Therapy / Q000295:instrumentation* / Q000379:methods; D012122:Ventilators, Mechanical
chemical_list: D009569:Nitric Oxide; D009585:Nitrogen Dioxide