title: Complete DNA sequence, comparative genomics, and prevalence of an IncHI2 plasmid occurring among extraintestinal pathogenic Escherichia coli isolates.
abstract: We have sequenced a large plasmid that occurs among avian pathogenic Escherichia coli isolates. This plasmid, pAPEC-O1-R, is a 241,387-bp IncHI2 plasmid which is cotransmissible via bacterial conjugation with a ColBM virulence plasmid, encodes resistance to eight antimicrobial agents, and appears to occur at low rates among extraintestinal E. coli isolates.
authors.affiliation: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, 1802 Elwood Drive, VMRI 2, Iowa State University, Ames, IA 50011, USA.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Johnson
authors.forename: Yvonne M
authors.initials: YM
authors.lastname: Wannemeuhler
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Scaccianoce
authors.forename: Sara J
authors.initials: SJ
authors.lastname: Johnson
authors.forename: Lisa K
authors.initials: LK
authors.lastname: Nolan
mesh_terms: D000818:Animals; D001483:Base Sequence; D002645:Chickens; D004269:DNA, Bacterial / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D004927:Escherichia coli Infections / Q000382:microbiology*; D023281:Genomics; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D004269:DNA, Bacterial