title: Obsessive-compulsive disorder due to neuroacanthocytosis treated with citalopram. A case report.
abstract: Neuroacanthocytois is a rare hereditary disease, which causes a degeneration of the striatum. Patients develop a choreatic movement disorder and also complex psychiatric symptoms, such as psychosis or Tourette's syndrome. We report a case of obsessive-compulsive disorder due to neuroacanthocytosis. The striatum plays an important role in the pathophysiology of obsessive-compulsive disorder. In Huntington's disease we also find obsessive-compulsive disorders, due to impairment of the fronto-striatal loop. Encouraged by similar pathophysiology and promising reports of selective serotonin reuptake inhibitors in this disease, we started a treatment with citalopram to which the patient responded very well.
authors.forename: B
authors.initials: B
authors.lastname: Habermeyer
authors.forename: P
authors.initials: P
authors.lastname: Fuhr
authors.forename: B
authors.initials: B
authors.lastname: Hiss
authors.forename: C
authors.initials: C
authors.lastname: Alber
authors.forename: F
authors.initials: F
authors.lastname: Müller-Spahn
mesh_terms: D000328:Adult; D002819:Chorea / Q000150:complications*; D015283:Citalopram / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000209:etiology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors