title: [Obstructive jaundice due to biliary cast syndrome followed by orthotopic liver transplantation].
abstract: Biliary complication occurs in 6-34% of all liver transplant patients. Although bile leaks and strictures are relatively common, other biliary complications such as T-tube leak, choledocholithiasis, and biliary cast syndrome can also be observed. The biliary cast syndrome describes the presence of casts causing obstruction with its resultant sequelae of biliary infection, hepatocyte damage secondary to bile stasis and ductal damage, all contributing to cholangiopathy. Because the exact timing of cast formation after orthotopic liver transplantation is not consistent, it is difficult to define the true incidence of biliary cast syndrome without long-term follow-up data. Proposed etiological mechanisms include acute cellular rejection, prolongation of cold ischemic time, infection, biliary drainage tubes, and biliary obstruction. The diagnosis of biliary cast syndrome is usually confirmed by endoscopic retrograde cholangiopancreatography. There have been few published articles about biliary casts in Korea. Herein, we report a case of biliary cast syndrome followed by orthotopic liver transplantation.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seongdong-gu, Seoul, Korea.
authors.forename: Sang Hyun
authors.initials: SH
authors.lastname: Bak
authors.forename: Ho Soon
authors.initials: HS
authors.lastname: Choi
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Yang
authors.forename: Dae Won
authors.initials: DW
authors.lastname: Jun
authors.forename: Sung Hee
authors.initials: SH
authors.lastname: Han
authors.forename: Hang Lak
authors.initials: HL
authors.lastname: Lee
authors.forename: Oh Young
authors.initials: OY
authors.lastname: Lee
authors.forename: Byung Chul
authors.initials: BC
authors.lastname: Yoon
authors.forename: Jun Soo
authors.initials: JS
authors.lastname: Hahm
authors.forename: Min Ho
authors.initials: MH
authors.lastname: Lee
authors.forename: Dong Hoo
authors.initials: DH
authors.lastname: Lee
authors.forename: Choon Suhk
authors.initials: CS
authors.lastname: Kee
mesh_terms: D000328:Adult; D001649:Bile Duct Diseases / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013577:Syndrome