title: Validation of a clinical finite element model of the human lumbosacral spine.
abstract: Very few finite element models on the lumbosacral spine have been reported because of its unique biomechanical characteristics. In addition, most of these lumbosacral spine models have been only validated with rotation at single moment values, ignoring the inherent nonlinear nature of the moment-rotation response of the spine. Because a majority of lumbar spine surgeries are performed between L4 and S1 levels, and the confidence in the stress analysis output depends on the model validation, the objective of the present study was to develop a unique finite element model of the lumbosacral junction. The clinically applicable model was validated throughout the entire nonlinear range. It was developed using computed tomography scans, subjected to flexion and extension, and left and right lateral bending loads, and quantitatively validated with cumulative variance analyses. Validation results for each loading mode and for each motion segment (L4-L5, L5-S1) and bisegment (L4-S1) are presented in the paper.
authors.affiliation: Department of Neurosurgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Yabo
authors.initials: Y
authors.lastname: Guan
authors.forename: Narayan
authors.initials: N
authors.lastname: Yoganandan
authors.forename: Jiangyue
authors.initials: J
authors.lastname: Zhang
authors.forename: Frank A
authors.initials: FA
authors.lastname: Pintar
authors.forename: Joesph F
authors.initials: JF
authors.lastname: Cusick
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Wolfla
authors.forename: Dennis J
authors.initials: DJ
authors.lastname: Maiman
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002102:Cadaver; D020342:Finite Element Analysis; D006801:Humans; D008159:Lumbar Vertebrae / Q000033:anatomy & histology / Q000502:physiology; D008954:Models, Biological; D009068:Movement / Q000502:physiology; D012399:Rotation; D012447:Sacrum / Q000033:anatomy & histology / Q000502:physiology; D013131:Spine / Q000033:anatomy & histology / Q000502:physiology*; D013314:Stress, Mechanical