title: Potential additional indicators for pacemaker requirement in isolated congenital atrioventricular block.
abstract: Low heart rate is the predominantly used indication for pacemaker intervention in patients with isolated congenital atrioventricular block (CAVB). The aim of this study was to compare the difference in heart rates recorded with ECG and Holter monitoring between paced (PM) and nonpaced (NPM) patients with isolated CAVB before pacemaker implantation to identify additional predictors for future PM need. Retrospective evaluation of atrial and ventricular rates (electrocardiography) and minimal and maximal (Holter) heart rates in 129 CAVB patients prior to PM implantation (n = 93) was performed, and results are expressed in V adjusted for age and sex. The average V score for the atrial rate was 0.51 (n = 50) in the PM group and 0.60 (n = 22) in the NPM group (not-significant). The average z score for the ventricular (average) rate was -0.91 (n = 83) in the PM group and -0.93 (n = 33) in the NPM group (not-significant). Minimal heart rate was -0.94 (n = 61) in the PM group and -0.86 (n = 25) in the NPM group (not significant). Maximal heart rate was -0.96 (n = 61) in the PM group and -0.95 (n = 26) in the NPM group (not significant). Initial recordings of the average heart rate and the minimal and maximal heart rate recorded during Holter monitoring do not seem to predict future pacemaker need in patients with CAVB. Studies with exercise stress tests are needed to confirm these findings.
authors.affiliation: Department of Obstetrics, University Medical Center, Utrecht, The Netherlands. hans_breur@hotmail.com
authors.forename: J M P J
authors.initials: JM
authors.lastname: Breur
authors.forename: F E A
authors.initials: FE
authors.lastname: Udink ten Cate
authors.forename: L
authors.initials: L
authors.lastname: Kapusta
authors.forename: N
authors.initials: N
authors.lastname: Boramanand
authors.forename: M I
authors.initials: MI
authors.lastname: Cohen
authors.forename: J E
authors.initials: JE
authors.lastname: Crosson
authors.forename: L J
authors.initials: LJ
authors.lastname: Lubbers
authors.forename: A H
authors.initials: AH
authors.lastname: Friedman
authors.forename: J I
authors.initials: JI
authors.lastname: Brenner
authors.forename: V L
authors.initials: VL
authors.lastname: Vetter
authors.forename: E J
authors.initials: EJ
authors.lastname: Meijboom
mesh_terms: D002304:Cardiac Pacing, Artificial / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D015716:Electrocardiography, Ambulatory; D005260:Female; D005500:Follow-Up Studies; D006327:Heart Block / Q000151:congenital / Q000503:physiopathology / Q000628:therapy; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010138:Pacemaker, Artificial; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome