title: A sensitized europium complex generated by micromolar concentrations of copper(I): toward the detection of copper(I) in biology.
abstract: Formation of a luminescent device by the Huisgen 1,3-dipolar cycloaddition reaction between a Eu(III) complex and dansyl azide is reported. This reaction is catalyzed by a common biological copper(I) complex [GS--Cu(I)], and the resultant copper(I) catalytic sensor shows a 10-fold enhancement of europium luminescence emission.
authors.affiliation: School of Chemistry, The University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, United Kingdom.
authors.forename: Romain F H
authors.initials: RF
authors.lastname: Viguier
authors.forename: Alison N
authors.initials: AN
authors.lastname: Hulme
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002384:Catalysis; D003300:Copper / Q000032:analysis*; D019327:Copper Sulfate / Q000737:chemistry; D003619:Dansyl Compounds / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D005978:Glutathione / Q000737:chemistry; D008163:Luminescent Measurements; D008832:Microchemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D003619:Dansyl Compounds; D009942:Organometallic Compounds; C042514:cuprous ion; D005063:Europium; D003300:Copper; D005978:Glutathione; D019327:Copper Sulfate