Early cerebrovascular disease in a 2-year-old with extreme obesity and complete metabolic syndrome due to feeding of excessively high amounts of energy.
A 2-year-old morbidly obese boy presented with early manifestation of vascular disease associated with several obesity-related features of the metabolic syndrome due to massive overfeeding. Ultrasound of the carotid arteries showed significant thickening of the intima media, perfusion magnetic resonance spectroscopy indicated cerebral microcirculation disturbance, and echocardiography revealed left ventricular hypertrophy. Thorough assessment of morbidly obese children seems to be of importance from early childhood on. Studies evaluating the prevalence of obesity-related metabolic and vascular comorbidities in very young morbidly obese children are warranted.
Weghuber
Daniel
D
Division of Metabolism and Nutrition, Department of Pediatrics, Vienna Medical University, Vienna, Austria.
Zaknun
Daniela
D
Nasel
Christian
C
Willforth-Ehringer
Andrea
A
Müller
Thomas
T
Boriss-Riedl
Marion
M
Widhalm
Kurt
K
D017536:Carotid Artery, Common / Q000000981:diagnostic imaging / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000453:epidemiology*; D002675:Child, Preschool; D006801:Humans; D006963:Hyperphagia / Q000453:epidemiology*; D017379:Hypertrophy, Left Ventricular / Q000453:epidemiology; D008279:Magnetic Resonance Imaging; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D009767:Obesity, Morbid / Q000453:epidemiology*; D017539:Tunica Intima / Q000473:pathology; D017540:Tunica Media / Q000473:pathology; D014463:Ultrasonography