title: The switch on the RAPper's necklace...
abstract: The biosynthesis and export of LDL receptor-related proteins rely on specialized chaperones in the endoplasmic reticulum. Two recent papers in Molecular Cell by Fisher et al. (2006) and Lee et al. (2006) reveal a novel mechanism by which one of these chaperones, the receptor-associated protein RAP, accomplishes this task.
authors.affiliation: Department of Molecular Genetics, University of Texas Southwestern, Dallas, Texas 75390, USA. joachim.herz@utsouthwestern.edu
authors.forename: Joachim
authors.initials: J
authors.lastname: Herz
mesh_terms: D000818:Animals; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006639:Histidine / Q000737:chemistry; D026563:LDL-Receptor Related Protein-Associated Protein / Q000737:chemistry / Q000378:metabolism*; D026502:LDL-Receptor Related Proteins / Q000378:metabolism
chemical_list: D026563:LDL-Receptor Related Protein-Associated Protein; D026502:LDL-Receptor Related Proteins; D006639:Histidine