title: [Juvenile granulosa cell tumor of the ovary. A case report].
abstract: Juvenile granulosa cell tumors of the ovary (JGCTs) are a rare form of neoplasm that makes up less than 5% of ovarians tumors in childhood and adolescence. About 90% are diagnosed in stage I (FIGO) with a favorable prognosis, whereas those at higher stages have a less favorable outecome. The authors describe a juvenile granulosa cell tumor expressed by an early pseudopuberty occurring in a 6 year old child. Clinically, an endocrine syndrome was associated with a pelvic mass. Hyperoestrogenia and serum alphafoetoprotein level were biologically detected. Tumor was localized strictly to the ovary, so conservative surgery was applied and proved sufficient to remove all tumor tissue. Histological examination showed typical microscopic aspect of a juvenile granulosa cell tumor. The patient is well, 14 years after surgery with a normal growth and mental developpment.
authors.affiliation: Service de chirurgie carcinologique, Institut Salah Azaiez.
authors.forename: Moez
authors.initials: M
authors.lastname: Kdous
authors.forename: Rim
authors.initials: R
authors.lastname: Hachicha
authors.forename: Amor
authors.initials: A
authors.lastname: Gamoudi
authors.forename: Hamouda
authors.initials: H
authors.lastname: Boussen
authors.forename: Farouk
authors.initials: F
authors.lastname: Benna
authors.forename: Khaled
authors.initials: K
authors.lastname: Rahal
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D002648:Child; D004958:Estradiol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006106:Granulosa Cell Tumor / Q000175:diagnosis*; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D010052:Ovariectomy; D011629:Puberty, Precocious / Q000175:diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; D004958:Estradiol