title: [Pseudoxanthoma elasticum: a report of 11 cases].
abstract: BACKGROUND
  Pseudoxanthoma elasticum (PXE) is an inherited disorder of elastic tissue with many systemic manifestations
  
  
  METHODS
  We performed a retrospective study from all the patients diagnosed with PXE at the department of dermatology of La Rabta hospital of Tunis, between 1986 and 2003.
  
  
  RESULTS
  During the observation period, we identified 11 patients with PXE, 5 males and 6 females with a mean age of 28 years (10-47 years). Family history was found in 5 patients. Exhibit yellowish, pigskin, and popular lesions on the sides of the neck were observed in all cases. Systematic ophthalmologic examination revealed angioïd streaks in 4 patients. No abnormalities were found in cardiovascular and metabolic explorations.
  
  
  CONCLUSIONS
  Diagnosis of PXE is based on clinical, histological and genetic criteria. Ocular and cardiovascular damage make all the gravity of the disease, from where interest of an ophthalmologic and cardiovascular examination systematic.
authors.affiliation: Service de Dermatologie, Hôpital La Rabta, Tunis, Tunisie.
authors.forename: Inès
authors.initials: I
authors.lastname: Zaraa
authors.forename: Faika
authors.initials: F
authors.lastname: Cherif
authors.forename: Fadoua
authors.initials: F
authors.lastname: Abdelmoula
authors.forename: Mourad
authors.initials: M
authors.lastname: Mokni
authors.forename: Naoufel
authors.initials: N
authors.lastname: Ben Tekaya
authors.forename: Slim
authors.initials: S
authors.lastname: Haouet
authors.forename: Dhahri Amel
authors.initials: DA
authors.lastname: Ben Osman
mesh_terms: D000328:Adult; D000793:Angioid Streaks / Q000175:diagnosis; D001706:Biopsy; D002114:Calcinosis / Q000473:pathology; D002648:Child; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D011561:Pseudoxanthoma Elasticum / Q000175:diagnosis* / Q000235:genetics; D012189:Retrospective Studies