Concurrence of Sjögren's syndrome in a patient with Chlamydia-induced reactive arthritis; an unusual finding.
A 40-year-old Korean man presented with painful swelling and tenderness of both ankle joints as well as the plantar surfaces of both feet, along with inflammatory back pain, and a purulent discharge from the urethral orifice. The patient also complained of sicca-like symptoms including dry eyes and dry mouth. An immunological analysis revealed a high titer of rheumatoid factor, positive results for antinuclear antibody and anti-Ro antibody, and a positive result for HLA-B27. An antibody titer for Chlamydia was also significantly increased. Positive results of the Schirmer's test and for keratoconjunctivitis sicca were confirmed by an ophthalmologist. These clinical manifestations were compatible with Chlamydia-induced reactive arthritis (ReA) accompanied by Sjögren's syndrome (SS). This is the first report of the combination of these two distinct disease entities in the Korean population.
Chang
Hyun Kyu
HK
Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea.
Bang
Ki Tae
KT
Lee
Bo Han
BH
Kim
Jung Hyuk
JH
Bae
Kang Woo
KW
Kim
Myong Jin
MJ
Kim
Seong-Kyu
SK
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D016918:Arthritis, Reactive / Q000150:complications*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis; D006801:Humans; D008297:Male; D000091402:Prohibitins; D012859:Sjogren's Syndrome / Q000150:complications*
D000974:Antibodies, Antinuclear; C000717331:PHB2 protein, human; D000091402:Prohibitins