title: A single somatic activating Asp578His mutation of the luteinizing hormone receptor causes Leydig cell tumour in boys with gonadotropin-independent precocious puberty.
authors.forename: Catarina B
authors.initials: CB
authors.lastname: d'Alva
authors.forename: Vinicius N
authors.initials: VN
authors.lastname: Brito
authors.forename: Heloisa M C
authors.initials: HM
authors.lastname: Palhares
authors.forename: Filomena M
authors.initials: FM
authors.lastname: Carvalho
authors.forename: Ivo J P
authors.initials: IJ
authors.lastname: Arnhold
authors.forename: Berenice B
authors.initials: BB
authors.lastname: Mendonca
authors.forename: Ana Claudia
authors.initials: AC
authors.lastname: Latronico
mesh_terms: D002648:Child; D006801:Humans; D007984:Leydig Cell Tumor / Q000235:genetics*; D008297:Male; D017354:Point Mutation; D011629:Puberty, Precocious / Q000235:genetics*; D011974:Receptors, LH / Q000235:genetics*; D013736:Testicular Neoplasms / Q000235:genetics*
chemical_list: D011974:Receptors, LH