title: Squamous cell carcinoma of the rectum in ulcerative colitis: case report and review of the literature.
abstract: The majority of colorectal carcinomas diagnosed are adenocarcinomas. Squamous cell carcinomas (SCC) of the rectum are rare tumors, and were reported as rare complication of inflammatory bowel disease. Surgery is the most effective therapy; and adjuvant chemotherapy and radiotherapy should also be considered. We report two cases of ulcerative colitis-associated SCC of the rectum. The lesions were treated with chemoradiotherapy with complete response.
authors.affiliation: Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA.
authors.forename: Alon J
authors.initials: AJ
authors.lastname: Pikarsky
authors.forename: Bruce
authors.initials: B
authors.lastname: Belin
authors.forename: Jonathan
authors.initials: J
authors.lastname: Efron
authors.forename: Sherry
authors.initials: S
authors.lastname: Woodhouse
authors.forename: Eric G
authors.initials: EG
authors.lastname: Weiss
authors.forename: Steven D
authors.initials: SD
authors.lastname: Wexner
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Nogueras
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011878:Radiotherapy; D012004:Rectal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D012074:Remission Induction / Q000379:methods
chemical_list: D000970:Antineoplastic Agents