title: Illumina universal bead arrays.
abstract: This chapter describes an accurate, scalable, and flexible microarray technology. It includes a miniaturized array platform where each individual feature is quality controlled and a versatile assay that can be adapted for various genetic analyses, such as single nucleotide polymorphism genotyping, DNA methylation detection, and gene expression profiling. This chapter describes the concept of the BeadArray technology, two different Array of Arrays formats, the assay scheme and protocol, the performance of the system, and its use in large-scale genetic, epigenetic, and expression studies.
authors.affiliation: Illumina, Inc., San Diego, California, USA.
authors.forename: Jian-Bing
authors.initials: JB
authors.lastname: Fan
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Gunderson
authors.forename: Marina
authors.initials: M
authors.lastname: Bibikova
authors.forename: Joanne M
authors.initials: JM
authors.lastname: Yeakley
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.forename: Eliza
authors.initials: E
authors.lastname: Wickham Garcia
authors.forename: Lori L
authors.initials: LL
authors.lastname: Lebruska
authors.forename: Marc
authors.initials: M
authors.lastname: Laurent
authors.forename: Richard
authors.initials: R
authors.lastname: Shen
authors.forename: David
authors.initials: D
authors.lastname: Barker
mesh_terms: D000818:Animals; D006801:Humans; D008863:Microspheres; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods*