title: [Clinical and neurophysiological aspects of severe forms of autism in children].
abstract: The aim of the study was to elucidate fundamentals for the phenomenon of universality of childhood autism by comparison of clinical and neurophysiological features of its severest forms--children endogenous autism (CEA) and Rett's syndrome (RS). Each group included 20 patients. Both groups were similar by age-at-disease-onset, clinical appearances during the disease course and dynamics of psychopathological syndromes. The theta-rhythm is common for CEA and RS at the disease stage with marked signs of disease acuity, autism, regress and, therefore, may be regarded as a marker of severity and development delay. The universality of autism phenomenon in its severe forms was confirmed both at the clinical and neurophysiological levels.
authors.forename: N V
authors.initials: NV
authors.lastname: Simashkova
authors.forename: L P
authors.initials: LP
authors.lastname: Iakupova
authors.forename: V M
authors.initials: VM
authors.lastname: Bashina
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013826:Theta Rhythm