title: Perinatal hepatitis C virus infection: diagnosis and management.
abstract: Hepatitis C virus (HCV) infection in children is becoming an increasing challenge to health professionals. As our understanding of the disease evolves, so must our diagnostic and management strategies. In the 1990s, when HCV testing became available, children identified with HCV infection in the UK were mostly those who had required blood products, particularly those with haematological disorders. Acquiring knowledge of the natural history of HCV infection was confounded by the co-morbidity of iron overload, viral co-infection, and chemotherapy.
authors.affiliation: Children's Liver and GI Unit, St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK. Suzanne.davison@leedsth.nhs.uk
authors.forename: S M
authors.initials: SM
authors.lastname: Davison
authors.forename: G
authors.initials: G
authors.lastname: Mieli-Vergani
authors.forename: J
authors.initials: J
authors.lastname: Sira
authors.forename: D A
authors.initials: DA
authors.lastname: Kelly
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D006526:Hepatitis C / Q000175:diagnosis* / Q000188:drug therapy / Q000635:transmission; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical
chemical_list: D000998:Antiviral Agents