title: Cytokines and immunoglobulin-E in certain parasitic diseases.
abstract: Ninety Egyptian patients were classified into 7 groups, 6 with different parasitic infection and 10 normal controls. Forty patients with different schistosomiasis stages (1, 2 & 3) with compensated but the last one (stage 4) of decompansated schistosomiasis. Gs3 & 4 of mixed infections with schistosomiasis and HCV & HBV respectively. The last 3 patients groups were infected with toxoplasmosis, filariasis and hymenolepiasis nana. IL2, IL4 & Ig E levels were measured. The results showed significant increase in IL2 (P < 0.05), (P < 0.01), P < 0.01) & (P < 0.001) among stages (1, 2, 3 & 4) versus control respectively. In chronic schistosomiasis with HCV & HBV, significance was P = < 0.001 & P < 0.05 respectively, among toxoplasmosis, filariasis and hymenolepiasis patients, it was P = < 0.001, 0.05 & 0.01 respectively. The IL 4 level showed highly significant increase (P< 0.001) among stage 1, 2, Gs 2, 3 & 6. There was significant increase (P < 0.01) with stage 3 in Gs 4 & 5 but, without significance (P > 0.05) increased in decompensate schistosomiasis patients. IgE level and test of significance versus controls were given and results were discussed.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Mansoura University.
authors.forename: Atef M
authors.initials: AM
authors.lastname: Elshazly
authors.forename: Mohamed
authors.initials: M
authors.lastname: Soliman
authors.forename: Abdl-Hamid R
authors.initials: AH
authors.lastname: el-Adl
authors.forename: Mahmoud A H
authors.initials: MA
authors.lastname: Fouad
authors.forename: Wafah A S
authors.initials: WA
authors.lastname: Arafa
authors.forename: Tosson A
authors.initials: TA
authors.lastname: Morsy
mesh_terms: D016022:Case-Control Studies; D016207:Cytokines / Q000097:blood*; D005260:Female; D006505:Hepatitis / Q000097:blood / Q000150:complications / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007376:Interleukin-2 / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D008297:Male; D010272:Parasitic Diseases / Q000097:blood* / Q000276:immunology*; D012552:Schistosomiasis / Q000097:blood / Q000150:complications / Q000276:immunology
chemical_list: D016207:Cytokines; D007376:Interleukin-2; D015847:Interleukin-4; D007073:Immunoglobulin E