title: Effects of oxcarbazepine on cognitive function in children and adolescents with partial seizures.
abstract: The authors investigated the effect of oxcarbazepine on cognitive function in children and adolescents (6 to younger than 17 years of age) with newly diagnosed partial seizures in an open-label comparison with standard antiepileptic drug therapy (carbamazepine and valproate). No differences in cognitive tests were observed between oxcarbazepine and carbamazepine/valproate over a 6-month treatment period.
authors.affiliation: Neurologie, Spitalzentrum Biel, University Hospital, Bern, Switzerland.
authors.forename: F
authors.initials: F
authors.lastname: Donati
authors.forename: G
authors.initials: G
authors.lastname: Gobbi
authors.forename: J
authors.initials: J
authors.lastname: Campistol
authors.forename: G
authors.initials: G
authors.lastname: Rapatz
authors.forename: M
authors.initials: M
authors.lastname: Daehler
authors.forename: Y
authors.initials: Y
authors.lastname: Sturm
authors.forename: A P
authors.initials: AP
authors.lastname: Aldenkamp
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage; D002220:Carbamazepine / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D002648:Child; D003071:Cognition / Q000187:drug effects*; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D004338:Drug Combinations; D004828:Epilepsies, Partial / Q000188:drug therapy* / Q000453:epidemiology*; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D000078330:Oxcarbazepine; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D016896:Treatment Outcome; D014635:Valproic Acid / Q000008:administration & dosage*
chemical_list: D000927:Anticonvulsants; D004338:Drug Combinations; D002220:Carbamazepine; D014635:Valproic Acid; D000078330:Oxcarbazepine