title: A case of voltage-gated potassium channel antibody-related limbic encephalitis.
abstract: BACKGROUND
  A 56-year-old man presented to hospital with a 6-month history of recurrent episodes of altered behavior and 'odd' episodes. He had become apathetic and uninterested in his family. He had no relevant past medical or family history. General and physical neurological examinations were unremarkable, as was bedside cognitive testing.
  
  
  METHODS
  Brain MRI scan, 24-h electroencephalogram, serum and cerebrospinal fluid testing for voltage-gated potassium channel antibodies, blood screening for tumors, CT scans of the chest, abdomen and pelvis, whole-body PET scan, neuropsychological examination, brain 18F-fluorodeoxyglucose-PET scan.
  
  
  METHODS
  Voltage-gated potassium channel antibody-related limbic encephalitis.
  
  
  RESULTS
  Antiepileptic drugs, immunomodulatory therapy, oral steroids, plasma exchange.
authors.affiliation: Addenbrooke's Hospital, Cambridge, UK. timothy.harrower@addenbrookes.nhs.uk
authors.forename: Tim
authors.initials: T
authors.lastname: Harrower
authors.forename: Tom
authors.initials: T
authors.lastname: Foltynie
authors.forename: Luke
authors.initials: L
authors.lastname: Kartsounis
authors.forename: Rajith N
authors.initials: RN
authors.lastname: De Silva
authors.forename: John R
authors.initials: JR
authors.lastname: Hodges
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology*; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D020363:Limbic Encephalitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D024642:Potassium Channels, Voltage-Gated / Q000276:immunology*; D012964:Sodium / Q000097:blood; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D001323:Autoantibodies; D007155:Immunologic Factors; D024642:Potassium Channels, Voltage-Gated; D013256:Steroids; D012964:Sodium