Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress.
The effects of spirulina supplementation on preventing skeletal muscle damage on untrained human beings were examined. Sixteen students volunteered to take Spirulina platensis in addition to their normal diet for 3-weeks. Blood samples were taken after finishing the Bruce incremental treadmill exercise before and after treatment. The results showed that plasma concentrations of malondialdehyde (MDA) were significantly decreased after supplementation with spirulina (P < 0.05). The activity of blood superoxide dismutase (SOD) was significantly raised after supplementation with spirulina or soy protein (P < 0.05). Both of the blood glutathione peroxidaes (GPx) and lactate dehydrogenase (LDH) levels were significantly different between spirulina and soy protein supplementation by an ANCOVA analysis (P < 0.05). In addition, the lactate (LA) concentration was higher and the time to exhaustion (TE) was significantly extended in the spirulina trail (P < 0.05). These results suggest that ingestion of S. platensis showed preventive effect of the skeletal muscle damage and that probably led to postponement of the time of exhaustion during the all-out exercise.
Lu
Hsueh-Kuan
HK
Sport Science Research Center, National Taiwan College of Physical Education, Taichung, Taiwan. hklu@ntcpe.edu.tw
Hsieh
Chin-Cheng
CC
Hsu
Jen-Jung
JJ
Yang
Yuh-Kuan
YK
Chou
Hong-Nong
HN
D000328:Adult; D000458:Cyanobacteria; D019587:Dietary Supplements; D004311:Double-Blind Method; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D018763:Muscle Fatigue; D018482:Muscle, Skeletal / Q000293:injuries* / Q000382:microbiology / Q000503:physiopathology*; D018384:Oxidative Stress; D019936:Probiotics / Q000627:therapeutic use*