[Low-risk differentiated thyroid carcinoma--literature review and management guidelines].
The trend of increasing thyroid cancer has been recognized in Brazil as well as all over the world for several decades. The large use of simple and effective diagnostic tools has significantly contributed to this trend. It is estimated that small carcinomas found at surgery for benign thyroid disorders and by ultrasonography will be identified at greater frequency in the further years. Part of these tumors occurs in low-risk patients that may benefit of less aggressive management strategies. However, the characterization of low-risk patient is still confusing and we lack adequate markers to tell apart patients that may present a troublesome progression of the disease. Furthermore, the use of new follow-up methods has recently changed some guidelines. A multidisciplinary team, including basic scientists, endocrinologists, nuclear medicine physicians, thyroid surgeons and endocrine pathologists reviewed the pertinent literature and, based on their experience, propose some management guidelines for Brazilian patients with low-risk thyroid carcinomas.
Ward
Laura S
LS
Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas/UNICAMP, 13081-970 Campinas, SP. ward@unicamp.br
Marrone
Marilia
M
Camargo
Rosalinda Y
RY
Watanabe
Tomoko
T
Tincani
Alfio J
AJ
Matos
Patricia S
PS
Assumpção
Ligia V M
LV
Tomimori
Eduardo
E
Kulcsar
Marco Aurélio
MA
Nunes
Maria Tereza
MT
Nogueira
Célia R
CR
Kimura
Edna T
ET
D002291:Carcinoma, Papillary / Q000628:therapy*; D018265:Carcinoma, Papillary, Follicular / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D011379:Prognosis; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000628:therapy*