Phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis.
We studied the phenotype of peripheral blood lymphocytes and serum immunoglobulin concentration in patients with early rheumatoid arthritis and rheumatoid arthritis of more than 12 months duration. Subpopulations of CDIgM+, CD25+, and HLA-DR+ lymphocytes and IgA concentration differed in these groups of patients with rheumatoid arthritis. The count of lymphocytes carrying CDIgM+ and HLA-DR+ receptors correlated with activity of rheumatoid arthritis.
Timofeev
V T
VT
A I Nesterov Department of Faculty Therapy, Medical Faculty, Russian State Medical University, Russian Health Ministry, Moscow.
Shostak
N A
NA
Anichkov
D A
DA
Potanin
A Yu
AY
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011961:Receptors, Fc / Q000032:analysis*; D011971:Receptors, Immunologic / Q000032:analysis
D006684:HLA-DR Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D011961:Receptors, Fc; D011971:Receptors, Immunologic; C035311:immunoglobulin M receptor