Flavone c-glycosides from Trollius ledebouri reichb.
A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, 1H and 13C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on TPA-induced mice ear edema (in vivo).
Wu
X-A
XA
Laboratory of Phytochemistry, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Zhao
Y-M
YM
Yu
N-J
NJ
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D047309:Flavones / Q000737:chemistry* / Q000494:pharmacology*; D035264:Flowers / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D029626:Ranunculaceae / Q000737:chemistry*; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D000893:Anti-Inflammatory Agents; D047309:Flavones; D010936:Plant Extracts; D012997:Solvents