title: Nanocompatible chemistry toward fabrication of target-specific gold nanoparticles.
abstract: Nanocompatible chemistry which utilizes a novel nontoxic phosphino amino acid as a reducing agent has resulted in the development of therapeutically useful gold nanoparticles under biologically benign media. Stabilization of gold nanoparticles by the edible gum arabic matrix has provided an effective pathway toward in vivo stable target-specific gold nanoparticles.
authors.affiliation: Department of Radiology, University of Missouri-Columbia, Columbia, Missouri 65212, USA. kannanr@health.missouri.edu
authors.forename: Raghuraman
authors.initials: R
authors.lastname: Kannan
authors.forename: Valerie
authors.initials: V
authors.lastname: Rahing
authors.forename: Cathy
authors.initials: C
authors.lastname: Cutler
authors.forename: Ravi
authors.initials: R
authors.lastname: Pandrapragada
authors.forename: Kavita K
authors.initials: KK
authors.lastname: Katti
authors.forename: Vijaya
authors.initials: V
authors.lastname: Kattumuri
authors.forename: J David
authors.initials: JD
authors.lastname: Robertson
authors.forename: Stan J
authors.initials: SJ
authors.lastname: Casteel
authors.forename: Silvia
authors.initials: S
authors.lastname: Jurisson
authors.forename: Charles
authors.initials: C
authors.lastname: Smith
authors.forename: Evan
authors.initials: E
authors.lastname: Boote
authors.forename: Kattesh V
authors.initials: KV
authors.lastname: Katti
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000493:pharmacokinetics; D004355:Drug Stability; D006046:Gold / Q000737:chemistry* / Q000493:pharmacokinetics; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D008815:Mice, Inbred Strains; D046529:Microscopy, Electron, Transmission; D050997:Nanomedicine; D010316:Particle Size; D013499:Surface Properties; D014018:Tissue Distribution
chemical_list: D001672:Biocompatible Materials; D006046:Gold