title: All-trans-retinoic acid-induced myositis in a child with acute promyelocytic leukemia.
abstract: Anthracyclin-based regimens and all-transretinoic acid (ATRA, tretinoin) as differentiating agent are commonly utilized for the treatment of acute promylelocytic leukemia (APL). There are many adverse effects that may be seen during the use of ATRA in patients with APL. Of these, ATRA-induced myositis is rarely described in adults and rare in the children with APL. Herein, we report an 11-year-old girl with APL who developed ATRA-induced myositis during induction treatment.
authors.affiliation: Losev-Losante, Ankara Foundation of Children with Leukemia, Hospital For the Children with Leukemia, Ankara, Turkey.
authors.forename: Funda Erkasar
authors.initials: FE
authors.lastname: Citak
authors.forename: Ustun
authors.initials: U
authors.lastname: Ezer
authors.forename: Emel
authors.initials: E
authors.lastname: Akkaya
authors.forename: Nilgun
authors.initials: N
authors.lastname: Ozbulbul
authors.forename: Muhterem
authors.initials: M
authors.lastname: Bahce
authors.forename: Ahmet Emin
authors.initials: AE
authors.lastname: Kurekci
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications* / Q000188:drug therapy; D009220:Myositis / Q000139:chemically induced*; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D014212:Tretinoin