GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks.
BACKGROUND
Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community.


RESULTS
We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules.


BACKGROUND
The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca.
Vlasblom
James
J
Structural Biology and Biochemistry Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Wu
Samuel
S
Pu
Shuye
S
Superina
Mark
M
Liu
Gina
G
Orsi
Chris
C
Wodak
Shoshana J
SJ
D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D003205:Computing Methodologies; D020869:Gene Expression Profiling / Q000379:methods; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D025941:Protein Interaction Mapping / Q000379:methods*; D020543:Proteome / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D014584:User-Computer Interface
D020543:Proteome