Radical and superoxide scavenging activities of matairesinol and oxidized matairesinol.
The radical and superoxide scavenging activities of oxidized matairesinols were examined. It could be assumed that the free benzylic position was important for higher radical scavenging activity. The different level of activity was observed between 7'-oxomatairesinol (Mat 2) and 7-oxomatairesinol (Mat 3). The activity of 8-hydroxymatairesinol was lower than that of matairesinol (Mat 1). The superoxide scavenging activity of the oxidized matairesinols was also demonstrated for the first time. It is assumed that the pKa value of phenol in the oxidized matairesinols affected this activity.
Yamauchi
Satoshi
S
Faculty of Agriculture, Ehime University, Japan. syamauch@agr.ehime-u.ac.jp
Sugahara
Takuya
T
Nakashima
Yuki
Y
Okada
Akihiro
A
Akiyama
Koichi
K
Kishida
Taro
T
Maruyama
Masashi
M
Masuda
Toshiya
T
D016166:Free Radical Scavengers / Q000737:chemistry*; D005663:Furans / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry*; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013481:Superoxides / Q000737:chemistry*
D016166:Free Radical Scavengers; D005663:Furans; D017705:Lignans; D013481:Superoxides; C068935:matairesinol