title: GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks.
abstract: BACKGROUND
  Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community.
  
  
  RESULTS
  We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules.
  
  
  BACKGROUND
  The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca.
authors.affiliation: Structural Biology and Biochemistry Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
authors.forename: James
authors.initials: J
authors.lastname: Vlasblom
authors.forename: Samuel
authors.initials: S
authors.lastname: Wu
authors.forename: Shuye
authors.initials: S
authors.lastname: Pu
authors.forename: Mark
authors.initials: M
authors.lastname: Superina
authors.forename: Gina
authors.initials: G
authors.lastname: Liu
authors.forename: Chris
authors.initials: C
authors.lastname: Orsi
authors.forename: Shoshana J
authors.initials: SJ
authors.lastname: Wodak
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D003205:Computing Methodologies; D020869:Gene Expression Profiling / Q000379:methods; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D025941:Protein Interaction Mapping / Q000379:methods*; D020543:Proteome / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software; D014584:User-Computer Interface
chemical_list: D020543:Proteome