title: Primary orbital neuroblastoma in a neonate.
abstract: Neuroblastoma is an undifferentiated malignant tumor of the primitive neuroblasts. Orbital neuroblastoma is typically a metastatic tumor. We describe a two-days-old girl, who presented with a large tumor in her left orbit. Magnetic resonance imaging revealed that the tumor originated from the retrobulbar area, extending into the upper and lateral orbit. She was operated on the fifth day of life. A histopathologic diagnosis of neuroblastoma was made. Medical evaluation including chest roentgenogram, ultrasonography of the abdomen, whole body computerized tomogram and bone scintigraphy showed no evidence of systemic involvement or metastasis. Neuroblastoma should be considered in the differential diagnosis of neonatal orbital tumors.
authors.affiliation: Department of Neurosurgery, Celal Bayar University School of Medicine, Manisa, Turkey. hmirzai@yahoo.com
authors.forename: Hasan
authors.initials: H
authors.lastname: Mirzai
authors.forename: Esin F
authors.initials: EF
authors.lastname: Baser
authors.forename: Nermin
authors.initials: N
authors.lastname: Tansug
authors.forename: Nalan
authors.initials: N
authors.lastname: Nese
authors.forename: Aydin
authors.initials: A
authors.lastname: Isisag
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009447:Neuroblastoma / Q000175:diagnosis* / Q000601:surgery; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000601:surgery