title: [Clinical topographic findings in glioblastoma multiforme and the relation with motor impairment].
abstract: Glioblastoma multiforme (GBM) is the glial tumor with the highest grade of malignity. It mainly affects the cerebral hemispheres, presenting general or focal signs and symptoms, which depend on the size, the location of the lesion and rate of growth of the tumor.
  
  
  OBJECTIVE
  To analyze the relationship between motor impairment and GBM topography.
  
  
  METHODS
  We studied 43 cases of GBM, related to the age, gender, localization and motor impairment.
  
  
  RESULTS
  The occurrence of the tumor was preponderant in adults (mean age 55 years old), men (55.82%), and frontal lobe (approximately 40%). The principal motor impairment was hemiparesis, with the exception of 2 cases in the frontal lobe, 2 temporal, 1 parietal, 1 occipital and 1 frontotemporal.
  
  
  CONCLUSIONS
  The clinical-topographic findings lead to consider the infiltrative effects (broad lesions) are responsible for the motor impairment rather than compressive effects (located lesions).
authors.affiliation: Departamento de Patologia, Universidade Federal de Pernambuco, Avenida Hélio Falcão 505/601, 51021-070 Recife PE, Brazil. ricaglu@yahoo.com
authors.forename: Rita de Cássia G
authors.initials: Rde C
authors.lastname: Lucena
authors.forename: Roberto J V
authors.initials: RJ
authors.lastname: de Mello
authors.forename: José Ronaldo
authors.initials: JR
authors.lastname: Lessa
authors.forename: George M
authors.initials: GM
authors.lastname: Cavalcante
authors.forename: Marcelo
authors.initials: M
authors.lastname: Ribeiro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D005909:Glioblastoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000209:etiology*; D012189:Retrospective Studies; D014055:Tomography, Emission-Computed