A comparative evaluation of newer sedatives in conscious sedation.
This double blind study was undertaken to determine the safety and efficacy of orally administered newer sedatives and analgesics for conscious sedation in 120 child patients. Patients were randomly assigned into: Midazolam (I), Ketamine (II), Zolpidem (III), Midazolam plus Ketamine (IV), Midazolam plus Tramadol (V) and Zolpidem plus Tramadol (VI) groups of 20 each. Onset of action, level of sedation, ease of treatment completion, recovery time, and post-operative amnesia were assessed for all and compared. Midazolam plus ketamine was found the most effective combination providing a fast and adequate analgo-sedation in anxious and uncooperative child patients.
Koirala
Bandana
B
Department of Pedodontics and Preventive Dentistry, College of Dental Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. drkbandu@yahoo.com
Pandey
R K
RK
Saksen
A K
AK
Kumar
Rakesh
R
Sharma
Shivalal
S
D000700:Analgesics; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods*; D016854:Dental Anxiety / Q000188:drug therapy*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D006801:Humans; D006993:Hypnotics and Sedatives; D007649:Ketamine; D008874:Midazolam; D011725:Pyridines; D014147:Tramadol; D000077334:Zolpidem
D000700:Analgesics; D006993:Hypnotics and Sedatives; D011725:Pyridines; D014147:Tramadol; D007649:Ketamine; D000077334:Zolpidem; D008874:Midazolam