title: [Studies of the factors linked to the bacteriostatic ability of Lactobacillus in human vagina].
abstract: OBJECTIVE
  To study the factors linked to the bacteriostatic ability of Lactobacillus in human vagina, and the relationship between the Lactobacillus and the Candida albicans.
  
  
  METHODS
  The content of H2O2, in the upper culture mediums of Lactobacilli were detected at different incubation time. Selecting the strains with vary bacteriostatic ability by Oxford cup test, detecting pH of these strains cultured after different time. After co-cultivation of the Lactobacillus, which has the strongest bacteriostatic ability, Candida albicans and Staphylococci for different incubation time, quantities of these mixed cultures were investigated.
  
  
  RESULTS
  The date of pH and the size of the bacteriostatic ring are negative correlation. There is not obvious relationship between the ability of producing H2O2 and the bacteriostatic ability of Lactobacillus. The study of the relationship between bacteria shows that the quantity of Staphylococci is as this: Staphylococci alone > Staphylococci + Lactobacillus > Staphylococci + Lactobacillus + Candida albicans.
  
  
  CONCLUSIONS
  The bacteriostatic ability of Lactobacillus is positivly related to its acid producing ability, and is not obvious to H2O2 content. After 36 hours cultivation time, Candida albicans can boost up the bacteriostatic ability of Lactobacillus.
authors.affiliation: West China School of Public Health, Sichuan University, Chengdu 610041, China.
authors.forename: Qian-Ru
authors.initials: QR
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiang
authors.initials: X
authors.lastname: Liu
authors.forename: Jiu-Hong
authors.initials: JH
authors.lastname: He
mesh_terms: D000328:Adult; D000898:Antibiosis / Q000502:physiology*; D002176:Candida albicans / Q000254:growth & development; D003470:Culture Media; D005260:Female; D006801:Humans; D007778:Lactobacillus / Q000302:isolation & purification / Q000502:physiology*; D013210:Staphylococcus / Q000254:growth & development; D014621:Vagina / Q000382:microbiology*; D014626:Vaginal Smears
chemical_list: D003470:Culture Media