Novel transparent poly(silazane) derived solvent-resistant, bio-compatible microchannels and substrates: application in microsystem technology.
In this report we have described fabrication of preceramic polymer-derived transparent, solvent-resistant, thermally stable and bio-compatible microchannels and substrates using soft-lithography methods such as micromolding in capillary (MIMIC) and micromolding. The micromolding technique was preferred in the current work to fabricate channels by thermal and photo crosslinking of a commercially available poly(vinyl silazane) (VL 20, KION Corporation, USA). Both thermal and photo cured preceramic polymer channels were found to possess unique glass-like characteristics, such as transparency and chemical inertness. However, their surfaces were identified to be hydrophobic with a contact angle of 101 degrees . To have an insight on the nature of the surface groups present on the surface of the cured preceramic polymer, ATR-IR was carried out. The hydrophobic nature of the cured polymer was best utilized for direct patterning of protein by nonspecific binding.
Asthana
Amit
A
Department of Fine Chemical Engineering and Chemistry, College of Engineering, Chungnam National University, Yoseong Gu, Daejeon 305-764, Republic of Korea.
Asthana
Yamini
Y
Sung
In-Kyung
IK
Kim
Dong-Pyo
DP
D000818:Animals; D001593:Benzyl Compounds / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry*; D002021:Buffers; D002417:Cattle; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D049452:Green Fluorescent Proteins / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D046210:Microfluidic Analytical Techniques; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence; D011108:Polymers / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry; D012828:Silicones / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013696:Temperature; D013997:Time Factors
D001593:Benzyl Compounds; D001672:Biocompatible Materials; D002021:Buffers; D004129:Dimethylpolysiloxanes; D005456:Fluorescent Dyes; D011108:Polymers; D012828:Silicones; D012997:Solvents; D049452:Green Fluorescent Proteins; D012710:Serum Albumin, Bovine; C013830:baysilon; D016650:Fluorescein-5-isothiocyanate; C037517:dicumyl peroxide