title: The high-resolution chest CT findings in an adult with Melnick-Needles syndrome.
abstract: Melnick-Needles syndrome is an X-linked dominant skeletal dysplasia in which patients often succumb at an early age to chronic pulmonary disease. Radiographic findings of Melnick-Needles syndrome consist of characteristic bony abnormalities and interstitial lung disease. We present the high-resolution computed tomographic (CT) findings in a 39-year-old survivor of Melnick-Needles syndrome. The clinical and physical exam findings also demonstrate an association between Melnick-Needles syndrome and obstructive sleep apnea.
authors.affiliation: Department of Radiology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
authors.forename: Derrick
authors.initials: D
authors.lastname: Harper
authors.forename: David A
authors.initials: DA
authors.lastname: Bloom
authors.forename: James A
authors.initials: JA
authors.lastname: Rowley
authors.forename: Ayman
authors.initials: A
authors.lastname: Soubani
authors.forename: Wilbur L
authors.initials: WL
authors.lastname: Smith
mesh_terms: D000328:Adult; D005260:Female; D040181:Genetic Diseases, X-Linked / Q000175:diagnosis*; D006801:Humans; D010009:Osteochondrodysplasias / Q000150:complications / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic; D012129:Respiratory Function Tests; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed