Cytokines and invertebrates: TGF-beta and PDGF.
The review outlines the presence and function of TGF-beta and PDGF family members in invertebrates. TGF-beta and PDGF play an important role in development, in immune and neuroendocrine responses and in the wound repair by activating the classical transduction pathways. Generally speaking, these cytokines appear very early in evolution and conserve their functions.
Franchini
A
A
Department of Animal Biology, University of Modena and R. Emilia, Modena, Italy.
Malagoli
D
D
Ottaviani
E
E
D000818:Animals; D006801:Humans; D007448:Invertebrates / Q000502:physiology*; D010982:Platelet-Derived Growth Factor / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D016212:Transforming Growth Factor beta / Q000502:physiology*
D010982:Platelet-Derived Growth Factor; D016212:Transforming Growth Factor beta