title: [Acquired von Willebrand syndrome].
abstract: Acquired von Willebrand syndrome (aVWS) is a rare, but probably underestimated, bleeding disorder that mimics the congenital form of von Willebrand disease (VWD) in terms of laboratory findings and clinical presentation. However, unlike congenital VWD, it arises in individuals with no personal or family history of bleeding. AVWS occurs in association with a variety of underlying disorders, including lymphoproliferative disorders, myeloproliferative disorders and cardiovascular diseases. The main pathogenic, clinical, laboratory and therapeutic aspects of this syndrome are concisely reported in this review.
authors.affiliation: Servizio di Immunoematologia e Trasfusione, Centro Emofilia, Azienda Ospedaliera, Verona. mfranchini@univr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
mesh_terms: D006801:Humans; D013577:Syndrome; D014842:von Willebrand Diseases / Q000097:blood / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D014841:von Willebrand Factor / Q000378:metabolism*
chemical_list: D014841:von Willebrand Factor