title: [Dependence of acute opiate poisoning lethal outcome on the gender, age, and duration of addiction].
abstract: The article presents toxicological characteristics of 198 cases of acute parenteral poisoning with morphine and heroin in the range of concentrations of their metabolites in the blood and urine which occur in practice. Risk of death is quantified in the range of possible morphine concentrations in the blood in acute opiates intoxication with reference to gender and age. Assessment of the criteria of quantitative opiates toxicity was made according to the method of logit regression and dose-effect curve suitable for analysis of correlations between probability of death and blood concentrations of opiates metabolites. Conditional lethal doses in respect to gender and age are calculated.
authors.forename: S V
authors.initials: SV
authors.lastname: Shigeev
authors.forename: V V
authors.initials: VV
authors.lastname: Zharov
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D049429:Forensic Pathology; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009294:Narcotics / Q000097:blood / Q000506:poisoning*; D009293:Opioid-Related Disorders / Q000097:blood / Q000401:mortality*; D011336:Probability; D012737:Sex Factors; D013997:Time Factors
chemical_list: D009294:Narcotics