title: Counterfeit anti-infective drugs.
abstract: The production of counterfeit or substandard anti-infective drugs is a widespread and under-recognised problem that contributes to morbidity, mortality, and drug resistance, and leads to spurious reporting of resistance and toxicity and loss of confidence in health-care systems. Counterfeit drugs particularly affect the most disadvantaged people in poor countries. Although advances in forensic chemical analysis and simple field tests will enhance drug quality monitoring, improved access to inexpensive genuine medicines, support of drug regulatory authorities, more open reporting, vigorous law enforcement, and more international cooperation with determined political leadership will be essential to counter this threat.
authors.affiliation: Wellcome Trust--Mahosot Hospital--Oxford Tropical Medicine Research Collaboration, Microbiology Laboratory, Mahosot Hospital, Vientiane, Laos. paul@tropmedres.ac
authors.forename: Paul N
authors.initials: PN
authors.lastname: Newton
authors.forename: Michael D
authors.initials: MD
authors.lastname: Green
authors.forename: Facundo M
authors.initials: FM
authors.lastname: Fernández
authors.forename: Nicholas P J
authors.initials: NP
authors.lastname: Day
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: White
mesh_terms: D000890:Anti-Infective Agents / Q000592:standards*; D006801:Humans; D007880:Legislation, Drug / Q000592:standards*; D004364:Pharmaceutical Preparations / Q000592:standards*; D006113:United Kingdom; D014481:United States
chemical_list: D000890:Anti-Infective Agents; D004364:Pharmaceutical Preparations