title: Novel conserved assembly factor of the bacterial flagellum.
abstract: TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.
authors.affiliation: Institute of Genetics, Forschungszentrum Karlsruhe, Box 3640, D-76021 Karlsruhe, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Titz
authors.forename: Seesandra V
authors.initials: SV
authors.lastname: Rajagopala
authors.forename: Claudia
authors.initials: C
authors.lastname: Ester
authors.forename: Roman
authors.initials: R
authors.lastname: Häuser
authors.forename: Peter
authors.initials: P
authors.lastname: Uetz
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics / Q000502:physiology; D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D016123:Campylobacter jejuni / Q000235:genetics / Q000502:physiology; D005407:Flagella / Q000235:genetics / Q000502:physiology*; D005408:Flagellin / Q000378:metabolism*; D009068:Movement; D014210:Treponema pallidum / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure
chemical_list: D001426:Bacterial Proteins; D005408:Flagellin