[The peculiarities of immune status of patients with coronary heart disease in the predoperative period during the individual year].
The aim of the study was to evaluate the influence of the individual annual cycle (IAC), a period from one birthday to another, on the immune status of patients with coronary heart disease (CHD). The subjects, 146 male CHD patients, were hospitalized to undergo coronary bypass surgery (CBS). The preoperative period in patients who were operated on in the 4th IAC trimester was characterized by significant changes in cell immunity parameters, such as a decrease in the relative number of T-lymphocytes, T-helpers, and NK cells, which was associated with a significant increase in the frequency of pyoseptic complications after CBS. During the 1st IAC trimester there was an increase in the functional activity of polymorphonuclear leucocytes and monocyte level elevation, which corresponded with an increase in the number of coronarogenic complications. The data obtained demonstrate the dependence of the immune index dynamics of CHD patients on their IAC.
Fomina
N V
NV
Barbarash
O L
OL
Lazik
N I
NI
D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000276:immunology* / Q000601:surgery; D004562:Electrocardiography; D005080:Exercise Test; D005500:Follow-Up Studies; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000276:immunology; D011379:Prognosis; D012307:Risk Factors; D013601:T-Lymphocytes / Q000276:immunology*