The elusive yeast interactome.
Simple eukaryotic cells such as yeast could contain around 800 protein complexes, as two new comprehensive studies show. But slightly different approaches resulted in surprising differences between the two datasets, showing that more work is required to get a complete picture of the yeast interactome.
Goll
Johannes
J
Institut für Genetik, Forschungszentrum Karlsruhe, Box 3640, 76021 Karlsruhe, Germany.
Uetz
Peter
P
D016681:Genome, Fungal; D006801:Humans; D008954:Models, Biological; D020543:Proteome / Q000302:isolation & purification / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D020798:Two-Hybrid System Techniques
D020543:Proteome; D029701:Saccharomyces cerevisiae Proteins