Folic acid and the treatment of depression.
Reduced plasma, serum, or red blood cell folate is commonly found in major depressive illnesses. Supplementing antidepressant medication with folic acid enhances the therapeutic effect. Although more work is required to confirm these beneficial results, it is suggested that, meanwhile, 2 mg of folic acid should be given during the acute, continuation, and maintenance treatment of depression.
Abou-Saleh
Mohammed T
MT
Coppen
Alec
A
D003865:Major Depressive Disorder / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology; D004334:Drug Administration Schedule; D005494:Folic Acid Deficiency / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood / Q000453:epidemiology