title: Adenoendocrine cell carcinoma of the gallbladder: report of a case.
abstract: Adenoendocrine cell carcinoma of the gallbladder is an uncommon form of cancer. We treated a 36-year-old woman who came to us with a chief complaint of abdominal pain. The abnormality was diagnosed to be a tumor-like mass in the gallbladder, and adenomyomatosis of the gallbladder was strongly suspected. A laparoscopic cholecystectomy was successfully performed, and the histopathological finding was adenoendocrine cell carcinoma of the gallbladder. The tumor cells of the small round cell carcinoma partly stained positively for synaptophysin, neuron-specific enolase, and CD 56, while adenocarcinoma cells showed positive reactions to keratin, which was thus suggestive of adenoendocrine cell carcinoma. The patient is alive and doing well at 12 months after the treatment.
authors.affiliation: Division of Surgery, Jusendo General Hospital, 1-8-16 Ekimae, Koriyama 963-8585, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tsuchiya
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Endo
authors.forename: Takashi
authors.initials: T
authors.lastname: Yazawa
authors.forename: Atsuko
authors.initials: A
authors.lastname: Saito
authors.forename: Norio
authors.initials: N
authors.lastname: Inoue
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D018278:Carcinoma, Neuroendocrine / Q000473:pathology / Q000601:surgery*; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D016896:Treatment Outcome