Concise total synthesis of the marine natural product ageladine A.
A total synthesis of ageladine A has been achieved by exploiting a Pictet-Spengler-type condensation between 2-aminohistamine and 4,5-dibromo-2-formylpyrrole as the key step.
Shengule
Sudhir R
SR
Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.
Karuso
Peter
P
D047230:Agelas / Q000737:chemistry; D000818:Animals; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis*
C482289:Ageladine A; D011758:Pyrroles