Augur--a computational pipeline for whole genome microbial surface protein prediction and classification.
The analysis of protein function is a challenge and a major bottleneck towards well-annotated and analysed microbial genomes. In particular, bacterial surface proteins present an opportunity for pharmacological intervention and vaccine development. We present Augur, an automatic prediction pipeline that integrates major surface prediction algorithms and enables comparative analysis, classification and visualization for gram-positive bacteria on a genomic scale.


BACKGROUND
http://bioinfo.mikrobio.med.uni-giessen.de/augur
Billion
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Institute of Medical Microbiology, Justus-Liebig-University Frankfurter Strasse 107, D-35392 Giessen, Germany. Andre.Billion@mikrobio.med.uni-giessen.de
Ghai
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Chakraborty
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Hain
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D000465:Algorithms; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D001330:Electronic Data Processing; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D008390:Markov Chains; D008565:Membrane Proteins / Q000737:chemistry*; D008954:Models, Biological; D011506:Proteins / Q000737:chemistry; D040901:Proteomics / Q000379:methods*; D020539:Sequence Analysis, Protein
D001426:Bacterial Proteins; D008565:Membrane Proteins; D011506:Proteins