Some aspects of the application of internal pilot studies.
This is a discussion of the paper' Sample size recalculation in internal pilot study designs' by Tim Friede and Meinhard Kieser, appearing in this special issue on adaptive designs.
Lachenbruch
Peter A
PA
US Food and Drug Administration, USA. lachenbruchpa@aol.com
Wittes
Janet
J
D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D015233:Models, Statistical; D010865:Pilot Projects; D012107:Research Design / Q000706:statistics & numerical data*; D018401:Sample Size