Prevalence of human papillomavirus (HPV) in oral cavity and oropharynx.
The prevalence of human papillomavirus (HPV) in the oral cavity and oropharynx has not yet been as well studied as its infection of the vaginal tract. However, new study are emerge after the development of molecular biology techniques. The objective of this study is to show the prevalence of HPV in the oral cavity and the oropharynx. An ample bibliographic review was done showing a prevalence of HPV 6, 11 in a normal oral mucous membrane (latent infection). In oral benign lesions associated with HPV, a prevalence of HPV 6 and 11 was observed in squamous cell papilloma (SCP) and condylomas acuminatum, while HPV 2 and 57 were more prevalent in verruca vulgaris lesions. As for focal epithelial hyperplasia (FEH) and oral cancer, especially squamous cell carcinoma (SCC), the prevalence was of HPV 13 and 32, and HPV 16, respectively. The last findings are, nonetheless, controversial. The last findings are, nonetheless, controversial. Showed also discrepancy result the prevalence of human papillomavirus (HPV) in normal oral mucous (latent infection) and in oral cancer, however evidenced confirmatory result in oral benign lesions associated with virus.
Castro
Therezita Peixoto Patury Galvão
TP
Department of Otorhinolaryngol, FCMSCSP, UNCISAL, UFAL, Brazil.
Bussoloti Filho
Ivo
I
D052685:Alphapapillomavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D015139:Blotting, Southern; D004279:DNA, Viral; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D009059:Mouth Diseases / Q000382:microbiology*; D009061:Mouth Mucosa / Q000382:microbiology; D009062:Mouth Neoplasms / Q000382:microbiology; D009960:Oropharynx / Q000382:microbiology; D030361:Papillomavirus Infections / Q000150:complications / Q000382:microbiology*; D010608:Pharyngeal Diseases / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D015995:Prevalence
D004279:DNA, Viral