Endometrial thickness and volume by three-dimensional ultrasound one week after embryo transfer to detect pregnancy.
OBJECTIVE
Determine if the evaluation of endometrium one week after embryo transfer can predict pregnancy.


METHODS
Endometrial volume and thickness were evaluated by three-dimensional ultrasound in 40 patients one week after embryo transfer. These results were compared to serum pregnancy test performed one week later.


RESULTS
Twenty two patients have achieved pregnancy. A significant difference was found for endometrial volume: 6.49+/-1.97 mL vs. 3.40+/-1.11 mL (pregnant vs. not pregnant); and thickness: 11.15+/-2.75 mm vs. 9.77+/-1.85 mm. The ROC curve was used to detect the best cutoff values: endometrial volume of 3.48 mL (sensitivity-100%, specificity-68.2%) and endometrial thickness of 10.3 mm (sensitivity-72.2%, specificity-77.3%). The area under curve was significant higher for endometrial volume (0.909 vs. 0.745, P=0.027). No pregnancy was achieved in women who had an endometrial volume <3.8 mL (15 patients) or thickness < 7.9 mm (3 patients).


CONCLUSIONS
The endometrial volume and thickness were significant higher in pregnant women and this difference was more prominent for endometrial volume.
de Paula Martins
Wellington
W
Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brasil. wpmartins@gmail.com
Ferriani
Rui Alberto
RA
dos Reis
Rosana Maria
RM
Nastri
Carolina Oliveira
CO
Filho
Francisco Mauad
FM
D000328:Adult; D001938:Brazil; D004624:Embryo Transfer; D004717:Endometrium / Q000000981:diagnostic imaging*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D011247:Pregnancy; D011258:Pregnancy Tests / Q000379:methods*; D012372:ROC Curve; D014463:Ultrasonography