title: Direct C-H arylation of (hetero)arenes with aryl iodides via rhodium catalysis.
abstract: A new method for the catalytic C-H arylation of heteroarenes and arenes that manifests high activity paired with reasonably broad scope was developed. Under the catalytic influence of RhCl(CO){P[OCH(CF3)2]3}2 and Ag2CO3, the direct C-H arylation of heteroarenes/arenes with aryl/heteroaryl iodides took place to afford a range of biaryls in good to excellent yields with high regioselectivity. Thiophenes, furans, pyrroles, indoles, and alkoxybenzenes are applicable in this arylation protocol.
authors.affiliation: Department of Chemistry and Research Center for Materials Science, Nagoya University, Nagoya 464-8602, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yanagisawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Sudo
authors.forename: Ryoji
authors.initials: R
authors.lastname: Noyori
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis*; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry; D006573:Heterocyclic Compounds, 1-Ring / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry; D012238:Rhodium; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D005663:Furans; D006573:Heterocyclic Compounds, 1-Ring; D007462:Iodobenzenes; D011758:Pyrroles; D013876:Thiophenes; D012238:Rhodium