title: Field trials of low dose Bayluscide on snail hosts of schistosome and selected non-target organisms in sahelian Cameroon.
abstract: More than 85% of all cases of schistosomiasis in Cameroon occur in the northern sahelian half of the country representing 20% of the population. Several workers have advocated the integrated approach to schistosomiasis control, including snail control, but the death and decay of aquatic organisms, and fish kill that often follows Bayluscide application at the dose of 1 g/m3 decrease its acceptability. The present study was designed to assess the effect of lower Bayluscide doses on snail host and non-target fish, frog, the tadpole kill. Bayluscide was applied to study ponds at concentrations of 0, 0.25, 0.5, and 1 g/m3 (ppm). Pre and post application assessment of snails hosts of schistosomes, fish, frog, and tadpole kill were carried out. All 0.25, 0.5, and 1 g/m3 Bayluscide concentrations reduced snail population significantly. Bayluscide concentration of 0.50 g/m3 applied in two rounds of 0.25 g/m3 resulted in high snail mortality and low lethality to fish, frogs, and tadpoles. Further studies are needed to assess the cost-effectiveness of Bayluscide in the control of schistosomiasis following the simplified approach.
authors.affiliation: Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Cameroon. itakougang@yahoo.com
authors.forename: I
authors.initials: I
authors.lastname: Takougang
authors.forename: J
authors.initials: J
authors.lastname: Meli
authors.forename: F
authors.initials: F
authors.lastname: Angwafo
mesh_terms: D000818:Animals; D001001:Anura; D002033:Bulinus / Q000187:drug effects / Q000469:parasitology*; D002163:Cameroon; D004199:Disease Vectors; D004305:Dose-Response Relationship, Drug; D005399:Fishes; D007814:Larva / Q000187:drug effects; D008975:Molluscacides / Q000494:pharmacology*; D009534:Niclosamide / Q000494:pharmacology*; D012547:Schistosoma / Q000187:drug effects*
chemical_list: D008975:Molluscacides; D009534:Niclosamide