[A 32-year-old patient with diarrhoea and acute kidney failure].
A 32-year-old male patient presented in the emergency department of our hospital with acute vomiting and diarrhoea. He reported occasional non-severe diarrhoea over several years in the past. Furthermore, at the time of presentation the patient had had anuria for several days. A prerenal and postrenal origin of the renal failure was excluded. A renal biopsy was performed and histopathological examination displayed findings consistent with a haemolytic-uraemic syndrome but no signs of glomerulonephritis. MRI examination of the small bowel revealed inflammatory alterations typical for Crohn's disease, even without histological verification. We describe haemolytic-waemic syndrome as manifestation of Crohn's disease for the first time.
Hoffmeister
A
A
Medizinische Klinik und Poliklinik II, Universitätsklinikum Leipzig, Ph.-Rosenthal-Strasse 27, 04103, Leipzig, Germany. albrecht.hoffmeister@medizin.uni-leipzig.de
Wittenburg
H
H
Teich
N
N
Bachmann
A
A
Borte
G
G
Mössner
J
J
Achenbach
H
H
D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D001706:Biopsy; D003424:Crohn Disease / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology*; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis*; D006801:Humans; D007421:Intestine, Small / Q000473:pathology; D007668:Kidney / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D014839:Vomiting / Q000209:etiology