title: Primary hypertrophic osteoarthropathy (pachydermoperiostosis): a case report.
abstract: Hypertrophic osteoarthropathy is characterized by digital clubbing and periosteal reaction of long bones. Most cases are associated with malignancy or other conditions such as congenital heart disease, liver cirrhosis, pulmonary fibrosis, biliary atresia, and gastrointestinal polyps. We report a 19-year-old man presenting with arthritis, broadening of the fingers and clubbing of the fingers and toes for the previous 3 years. The ankles and knees were swollen. X-rays showed periosteal apposition. The search for a secondary cause remained negative. In cases of arthralgia/arthritis together with clubbed fingers, consideration must be given to hypertrophic osteoarthropathy. The primary or idiopathic form is rare and has a good prognosis.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Medical Faculty, Karadeniz Technical University, 61080, Trabzon, Turkey. muratkarkucak@yahoo.com
authors.forename: Murat
authors.initials: M
authors.lastname: Karkucak
authors.forename: Engin
authors.initials: E
authors.lastname: Erturk
authors.forename: Erhan
authors.initials: E
authors.lastname: Capkin
authors.forename: Hikmet
authors.initials: H
authors.lastname: Akyazi
authors.forename: Gonca
authors.initials: G
authors.lastname: Ozden
authors.forename: Mehmet
authors.initials: M
authors.lastname: Tosun
mesh_terms: D000328:Adult; D003078:Colchicine / Q000627:therapeutic use; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000175:diagnosis* / Q000188:drug therapy; D010522:Periostitis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011859:Radiography
chemical_list: D006074:Gout Suppressants; D003078:Colchicine