Clinical trial of a novel filler material for soft tissue augmentation of the face containing synthetic calcium hydroxylapatite microspheres.
BACKGROUND
The ideal injectable filler should yield great, long-lasting results, be biocompatible, reliable, safe, easy to use, and inexpensive. Radiesse (Bioform Inc., Franksville, WI) is a synthetic calcium hydroxylaptic filler that has all of the above qualities. OBJECTIVE To evaluate the effectiveness of Radiese as an injectable filler.


METHODS
Eighty-two patients who underwent facial soft tissue augmentation using Radiese from April 2003 to 2004 were enrolled in this study. Pre-filled sterile syringes were used to inject the material into the soft tissues of the face. At the 3 month and six month visits, the physicians and the patients were asked to evaluate the result.


RESULTS
Eighty-two patients were injected with Radiesse. The most common area of injection was the melolabial folds. All patients were evaluated during the 3 month follow up visit. There was an overwhelmingly positive response to the look and feel of the implant, averaging 4.6 on a grading scale from 1 to 5, for the patients as well as the injecting physicians. Similar responses were found at the 6 month follow up visit.


CONCLUSIONS
Preliminary data indicate that Radiesse is easy to use and effective with little or no associated morbidity.
Roy
Deborshi
D
Department of Otolaryngology, Lenox Hill Hospital, New York, New York, USA. droymd@sadickdermatology.com
Sadick
Neil
N
Mangat
Devinder
D
D001672:Biocompatible Materials / Q000008:administration & dosage*; D003357:Cosmetic Techniques; D017886:Durapatite / Q000008:administration & dosage*; D005145:Face; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008863:Microspheres; D017060:Patient Satisfaction; D012060:Rejuvenation; D012189:Retrospective Studies; D016896:Treatment Outcome
D001672:Biocompatible Materials; D017886:Durapatite