Retinal fibrovascular proliferation associated with Nocardia subretinal abscess.
OBJECTIVE
To report the development of extensive fibrovascular proliferation in association with Nocardia subretinal abscess.


METHODS
Case report.


RESULTS
Extensive retinal neovascularization with tractional retinal detachment developed soon after ocular involvement in a 61-year-old patient with systemic nocardiosis. Fundus fluorescein angiography showed extensive area of capillary nonperfusion and severe leakage from the neovascular complex. The Nocardia subretinal abscess responded to systemic antibiotics, and the retinal neovascularization and tractional retinal detachment stabilized after 3 months.


CONCLUSIONS
Retinal ischemia and severe retinal neovascularization may complicate intraocular nocardiosis. The authors propose secondary retinal vasculitis as a contributing factor towards the development of retinal ischemia in this setting.
Rafiei
N
N
The Wilmer Eye Institute, Johna Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD 21287, USA.
Tabandeh
H
H
Bhatti
M T
MT
Monshizadeh
R
R
D000038:Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D009616:Nocardia asteroides / Q000302:isolation & purification*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000276:immunology; D012163:Retinal Detachment / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015861:Retinal Neovascularization / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids