[Pharmacological effects of flavonoids from Scutellaria baicalensis].
Scutellaria baicalensis is a plant widely used in Chinese and Japanese herbal medicine. Dry roots of Scutellaria baicalensis are used, especially as alcohol extracts. Flavonoids isolated from Radix Scutellariae have beneficial effects in hepatitis. Flavonoids derived from Scutellaria baicalensis produce antioxidative, antineoplastic, cardiomiocyte-protective activity. They inhibit agregation of platelets, permeability of capillary vessels, have antibacterial and anty-angiogenic effects.
Kowalczyk
Edward
E
Zakład Fizjologii Człowieka i Biofizyki, Uniwersytetu Medycznego w łodzi. farmak@achilles.wam.lodz.pl
Krzesiński
Paweł
P
Kura
Marcin
M
Niedworok
Jan
J
Kowalski
Jan
J
Błaszczyk
Jan
J
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D031364:Scutellaria baicalensis / Q000737:chemistry* / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; D011451:Prostaglandin-Endoperoxide Synthases