title: Glucose tolerance and insulin sensitivity following an one-week volleyball competition.
abstract: The purpose of the study was to compare glucose tolerance and insulin sensitivity between trained (TR) and competition (CP) states, in relation to cortisol and testosterone levels. Sixteen highly trained volleyball players voluntarily participated in this study. The first testing session (TR state) occurred 1 week before the start of national level volleyball CP, and the second testing session (CP state) occurred next morning after the 1-week CP. Fasted serum sample was used for measuring cortisol and testosterone. Subjects were then orally challenged with 75 g of glucose solution for determinations of oral glucose tolerance test (OGTT) and insulin response. Under both fasted and glucose challenged conditions, glucose levels of CP were not different from TR state, whereas insulin levels of CP were significantly elevated above TR (50 min: from 78.8 +/- 8.7 to 96.6 +/- 8.1 microU/ml, P < 0.05; 80 min: from 62.8 +/- 7.0 to 82.0 +/- 7.3; P < 0.05). Muscle creatine kinase (CK) level in blood was significantly increased above TR, suggesting greater muscle damage by CP. Serum leptin level, percent fat mass, and body weight were not different between two states. CP significantly increased serum cortisol level without significantly change in testosterone level. The new finding of the study was that volleyball CP reduced the whole-body insulin sensitivity significantly compared to TR state. The greater level of insulin concentration under CP state appears to be associated with elevated serum cortisol level. Despites the benefit of increased physical activity on metabolic function is widely recognized, physiological stress associated with CP can result in attenuation of systemic insulin sensitivity compared TR state.
authors.affiliation: Laboratory of Exercise Biochemistry, Taipei Physical Education College, Taiwan, ROC.
authors.forename: Mao-Chuan
authors.initials: MC
authors.lastname: Kuo
authors.forename: Chia-Hau
authors.initials: CH
authors.lastname: Chou
authors.forename: Chung-Fong
authors.initials: CF
authors.lastname: Ho
authors.forename: Hsing-Hao
authors.initials: HH
authors.lastname: Lee
authors.forename: Wei-Hsiang
authors.initials: WH
authors.lastname: Chang
authors.forename: Tzi-Wen
authors.initials: TW
authors.lastname: Lin
authors.forename: Chien-Wen
authors.initials: CW
authors.lastname: Hou
authors.forename: Kuei-Yu
authors.initials: KY
authors.lastname: Chien
authors.forename: Te-Chih
authors.initials: TC
authors.lastname: Liu
authors.forename: Chia-Hua
authors.initials: CH
authors.lastname: Kuo
mesh_terms: D000293:Adolescent; D001823:Body Composition / Q000502:physiology; D003402:Creatine Kinase / Q000097:blood; D005951:Glucose Tolerance Test; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000502:physiology*; D013177:Sports / Q000502:physiology*; D013739:Testosterone / Q000097:blood
chemical_list: D007328:Insulin; D013739:Testosterone; D003402:Creatine Kinase; D006854:Hydrocortisone