[Sepsis following transrectal prostate biopsy: a report of 2 cases and reviewed similar cases in Japan].
We report two cases of sepsis and disseminated intravascular coagulation (DIC), potentially fatal complications, following transrectal prostate biopsy. We also review similar cases reported in Japan. Case 1: A 63-year-old man received a cathartic and levofloxacin (LVFX) for prophylaxis. After transrectal prostate biopsy, he presented with fever and chills. Blood cultures grew Escherichia coli resistant to LVFX. Under a diagnosis of sepsis, he received intensive management that included endotoxin removal therapy. The patient was hospitalized for 27 days. Case 2: A 64-year-old man received a cathartic and cefazolin (CEZ) for prophylaxis. He presented with fever and chills after biopsy, and was admitted to hospital. Blood cultures grew E. coli resistant to CEZ. Under a diagnosis of sepsis, he received intravenous antibiotics, transfusion, and anti-DIC drugs. The patient was hospitalized for 11 days.
Hoshi
Akio
A
The Department of Urology, Division of Surgery, Tokai University School of Medicine.
Nitta
Masahiro
M
Hongoh
Sachiko
S
Hanai
Kazuya
K
Nishikawa
Zenkai
Z
Kobayashi
Yasuyuki
Y
Shima
Masanori
M
Hanai
Tadashi
T
Hyochi
Nobuhiko
N
Usui
Yukio
Y
Miyakita
Hideshi
H
Terachi
Toshiro
T
D001706:Biopsy / Q000009:adverse effects*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004927:Escherichia coli Infections / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D012007:Rectum; D018805:Sepsis / Q000209:etiology*