title: Predictors of outcome in children with hydrocarbon poisoning receiving intensive care.
abstract: The retrospective study included 48 children between 8.5 months--10 years, admitted to the PICU of an urban, tertiary care, teaching hospital in northern India from January 1995 to December 2001. Eighteen (38%) patients were hypoxemic on arrival, of which 8 (45%) required mechanical ventilation. Compared to the non-hypoxemic children, the hypoxemic patients were more likely to have received gastric lavage before arrival to our center (Odds Ratio 23.2, 95% CI 2.4 - 560.7) and had higher frequency of severe respiratory distress and leucocytosis (Odds Ratio 8.0, 95% CI 1.79 -38.6). On multiple regression analysis, we could not identify any particular variable that could predict hypoxemia. Secondary pneumonia developed in 16 (33.3%), with the duration of PICU stay being longer in these patients as against those who did not (144 hours vs 72 hours, p <0.05). Two (4.2%) children died and one suffered hypoxic sequelae. Prior lavage, hypoxemia at admission, need for ventilation, secondary sepsis and ventilator related complications were associated with poor outcome.
authors.affiliation: Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India. medinst@pgi.chd.nic.in
authors.forename: M
authors.initials: M
authors.lastname: Jayashree
authors.forename: S
authors.initials: S
authors.lastname: Singhi
authors.forename: A
authors.initials: A
authors.lastname: Gupta
mesh_terms: D002648:Child; D002675:Child, Preschool; D003422:Critical Care; D005260:Female; D005751:Gastric Lavage / Q000706:statistics & numerical data; D006801:Humans; D006838:Hydrocarbons / Q000506:poisoning*; D000860:Hypoxia / Q000139:chemically induced / Q000150:complications / Q000628:therapy*; D007223:Infant; D015278:Intensive Care Units, Pediatric / Q000706:statistics & numerical data*; D008297:Male; D010102:Oxygen Inhalation Therapy / Q000706:statistics & numerical data; D012121:Respiration, Artificial; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014505:Urban Population
chemical_list: D006838:Hydrocarbons