Effect of residues remaining in the injection liner of a gas chromatograph on the quantification of polycyclic aromatic hydrocarbons by isotope dilution mass spectrometry using deuterium-labeled internal standards.
We have investigated the differences in response ratios of native polycyclic aromatic hydrocarbons (native PAHs)/13C-labeled PAHs (13C-PAHs) and of native PAHs/deuterium-labeled PAHs (PAHs-d) in a calibration solution containing at trace concentrations (< 1 microg mL(-1)) by gas chromatography-mass spectrometry. Only the ratios of native PAHs/PAHs-d decreased significantly (p < 0.05) accompanied with increase of residue amounts originated from immediately before injected solution. Since the analytical results using PAHs-d as internal standards were significantly lower than those using 13C-PAHs whatever solutions were injected immediately before (p < 0.05, 1.9-13.2%), 13C-PAHs gave more accurate results.
Itoh
Nobuyasu
N
National Metrology Institute of Japan (NMIJ), National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki 305-8563, Japan. nobuyasu-itoh@aist.go.jp
Numata
Masahiko
M
Aoyagi
Yoshie
Y
Yarita
Takashi
T
D016477:Artifacts; D002138:Calibration; D002247:Carbon Isotopes; D002849:Chromatography, Gas / Q000592:standards; D003903:Deuterium; D019015:Geologic Sediments / Q000737:chemistry; D007201:Indicator Dilution Techniques; D013058:Mass Spectrometry / Q000379:methods*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000737:chemistry; D012015:Reference Standards
D002247:Carbon Isotopes; D011084:Polycyclic Aromatic Hydrocarbons; D003903:Deuterium