Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump.
We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). In five cardiac-arrested pigs, the outflow cannula of the CP was inserted into the ascending aorta, the inflow cannula in the right atrium. A 30-ml IABP was subsequently placed in the descending aorta. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg per minute by CP alone or by IABP/CP with pressure and flow measured in the right internal carotid artery. The IABP/CP combination converted the flow to pulsatile and increased pulse pressure significantly from 9.1 +/- 1.3 mm Hg to 54.9 +/- 6.1 mm Hg (p = 0.012). It also significantly increased the percent change from mean arterial pressure to EEP from 0.2 +/- 0.3% to 23.3 +/- 6.1% (p = 0.012) and SHE from 133.2 +/- 234.5 erg/cm to 20,219.8 +/- 5842.7 erg/cm3 (p = 0.012). However, no statistical difference was observed between CP and IABP/CP in terms of mean carotid artery pressure (p = NS). In a cardiac-arrested animal model, pulsatility generated by a IABP/CP combination may be effective in terms of energy equivalent pressure and surplus hemodynamic energy.
Lim
Choon Hak
CH
Anesthesiology and Pain Medicine, Korea University, Seoul, Korea.
Son
Ho Sung
HS
Fang
Yung Hu
YH
Lee
Jung Joo
JJ
Baik
Kwang Je
KJ
Kim
Kyung Hyun
KH
Kim
Bum Soo
BS
Lee
Hye Won
HW
Sun
Kyung
K
D000818:Animals; D006328:Cardiac Catheterization / Q000379:methods; D002320:Cardiovascular Physiological Phenomena; D006353:Heart-Assist Devices; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D013552:Swine