title: Chapter 28: Studies to assess the long-term efficacy and effectiveness of HPV vaccination in developed and developing countries.
abstract: We review studies of the implementation of human papillomavirus (HPV) vaccination programmes in developed and developing countries. The review spans the period from establishment of long-term vaccine efficacy follow-up studies, operational research on issues of vaccine preparedness, and relevant predictive modelling studies during the pre-licensure phase to plans of phase IV effectiveness trials, forms of epidemiological surveillance, and further operational research in the post-licensure phase. Much of the research is already ongoing. Depending on the results of the planned immuno bridging studies among HIV-negative and HIV-positive women, further phase III and/or phase IV trials may be warranted.
authors.affiliation: National Public Health Institute, Department of Infectious Disease Epidemiology, KTL, Oulu, Finland. Matti.Lehtinen@uta.fi
authors.forename: Matti
authors.initials: M
authors.lastname: Lehtinen
authors.forename: Rolando
authors.initials: R
authors.lastname: Herrero
authors.forename: Philippe
authors.initials: P
authors.lastname: Mayaud
authors.forename: Ruanne
authors.initials: R
authors.lastname: Barnabas
authors.forename: Joakim
authors.initials: J
authors.lastname: Dillner
authors.forename: Jorma
authors.initials: J
authors.lastname: Paavonen
authors.forename: Peter G
authors.initials: PG
authors.lastname: Smith
mesh_terms: D019049:Developed Countries; D003906:Developing Countries; D006801:Humans; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000276:immunology*; D011358:Product Surveillance, Postmarketing; D012106:Research / Q000639:trends
chemical_list: D053918:Papillomavirus Vaccines