title: Radical cystectomy with ultrasound-guided partial prostatectomy for bladder cancer: a complication-preventing concept.
abstract: OBJECTIVE
  Radical cystectomy has been the reference standard for the treatment of muscle-invasive bladder cancer. However, this kind of therapy does have an impact on the patient's quality of life. For this reason, we performed prostate-sparing surgery during radical cystectomy without compromising the oncologic outcome.
  
  
  METHODS
  From December 2003 to August 2005, 31 patients with a mean age of 63.6 +/- 8 years (range 48 to 79) underwent apex-sparing radical cystoprostatectomy for invasive bladder cancer. All patients underwent transurethral biopsy in the prostatic urethra to exclude urothelial tumor and transrectal ultrasound-guided biopsy of the prostate to diagnose concomitant prostate cancer. Patients with a prostate-specific antigen level greater than 4 ng/mL were excluded from prostate-sparing cystectomy. The mean follow-up period was 12 months.
  
  
  RESULTS
  The postoperative pathologic stage was pTis in 2 patients, pTa in 1, pT1 in 3, pT2 in 20, pT3 in 5, and pN+ in 4 patients. We found no prostate cancer on histopathologic evaluation. Except for 4 patients, no patient had deterioration of sexual function. Except for 2 patients, all patients were fully continent.
  
  
  CONCLUSIONS
  Radical cystectomy with prostate-sparing surgery in patients with invasive bladder cancer resulted in improved continence and improved erectile function. Additionally, with apex-sparing radical cystoprostatectomy, we were able to create a wide neovesicourethral anastomosis to prevent strictures, urinary retention, and mucous retention. It is absolutely necessary that this procedure be restricted to highly selected patients.
authors.affiliation: Department of Urology, Friedrich-Schiller-University, Jena, Germany. heiko.wunderlich@med.uni-jena.de
authors.forename: Heiko
authors.initials: H
authors.lastname: Wunderlich
authors.forename: Marco
authors.initials: M
authors.lastname: Wolf
authors.forename: Olaf
authors.initials: O
authors.lastname: Reichelt
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Fröber
authors.forename: Jörg
authors.initials: J
authors.lastname: Schubert
mesh_terms: D000368:Aged; D015653:Cystectomy / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods*; D014463:Ultrasonography; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*