Differentiation of PC12 cells.
This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students. The background and details for performing the lab are provided along with suggestions for assessing student performance and understanding.
Adler
Elizabeth M
EM
American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA. eadler@aaas.org
Gough
Nancy R
NR
Blundon
Jay A
JA
D000818:Animals; D001695:Biology / Q000193:education*; D002454:Cell Differentiation; D007753:Laboratories; D009446:Neurobiology / Q000193:education; D016716:PC12 Cells; D051381:Rats; D013663:Teaching / Q000379:methods*; D014495:Universities