Further investigation of the tolerance and mechanical adjustability of the *Acri.Tec AR-1 PC/IOL in rabbit eyes: an intraocular lens with reversibly adjustable optical power.
OBJECTIVE
To examine the tolerance and mechanical function of an adjustable intraocular lens (IOL) in rabbit eyes.


METHODS
Implantation of the *Acri.Tec AR-1 PC/IOL into 14 rabbit eyes. Manipulation of the lens 8 weeks after implantation in order to change the refractive power. Follow-up for up to 5 months. Histopathologic examination of the eyes.


RESULTS
Implantation and mechanical adjustment of the PC/IOL were possible. Eyes healed normally. No difference between eyes containing the *Acri.Tec AR-1 PC/IOL and eyes containing the control PC/IOL could be detected with respect to signs of inflammatory reaction, corneal transparency, intraocular pressure and histopathologic appearance. Histopathologic examination of the eyes showed that the *Acri.Tec AR-1 PC/IOL did not cause any damage in rabbit eyes.


CONCLUSIONS
The *Acri.Tec AR-1 PC/IOL is well tolerated in rabbit eyes for extended periods of time, suggesting that this PC/IOL should be well tolerated in the long run. Surgical adjustment of the adjusting element can be performed with little effort several weeks after implantation.
Jahn
Claus E
CE
Augenpraxisklinik Dr. Jahn, Kempten, Germany.
Fromberg
Ingeborg
I
Fesser
Nicole
N
Allgoewer
Ingrid
I
Jahn
Christoph H
CH
Wakili
Nina S
NS
Hofmann-Rummelt
Carmen R
CR
Holbach
Leonard M
LM
Kamppeter
Bernd A
BA
D000818:Animals; D001672:Biocompatible Materials; D007108:Immune Tolerance; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000601:surgery; D007910:Lenses, Intraocular; D055095:Optics and Photonics; D019904:Polymethyl Methacrylate; D011474:Prosthesis Design; D017755:Prosthesis Fitting; D011817:Rabbits
D001672:Biocompatible Materials; D019904:Polymethyl Methacrylate