Genetic characterization of the H9N2 influenza viruses circulated in the poultry population in Israel.
The partial nucleotide sequences of the hemagglutinin (HA) genes of 72 H9N2 influenza viruses isolated from chickens and turkeys in Israel during the period 2000-2005 were genetically analyzed. The isolates possessed the three types of amino acid motif -R-S-S-R/G-L-, -R-S-N-R/G-L-, and -R-S-K-R/G-L- at the cleavage site of HA. Phylogenetic analyses showed that all Israeli isolates belonged to the same group which further divided into three closely related sub-groups. The HA genes of these isolates were related to the HA gene of A/chicken/Germany/R45/98 isolated from chicken in Germany in 1998.
Perk
Shimon
S
Division of Avian and Aquatic Animals Diseases, Kimron Veterinary Institute, Beit Dagan, ZC 50250, Israel.
Banet-Noach
Caroline
C
Shihmanter
Ester
E
Pokamunski
Shimon
S
Pirak
Michael
M
Lipkind
Michael
M
Panshin
Alexander
A
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens; D004196:Disease Outbreaks / Q000662:veterinary*; D006386:Hemagglutination Tests; D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000235:genetics; D053127:Influenza A Virus, H9N2 Subtype / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D007557:Israel / Q000453:epidemiology; D008969:Molecular Sequence Data; D009439:Neuraminidase / Q000037:antagonists & inhibitors; D010802:Phylogeny; D011201:Poultry Diseases / Q000453:epidemiology / Q000821:virology*; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D016415:Sequence Alignment; D014422:Turkeys
D006389:Hemagglutinins, Viral; D012367:RNA, Viral; D009439:Neuraminidase