Fibroepithelioma of pinkus.
An 88-year-old woman presented with an 8-year history of a slowly enlarging growth on the suprapubic area. A shave excision of this lesion demonstrated fibroepithelioma of Pinkus (FEP). Fibroepithelioma of Pinkus is an indolent growing tumor that traditionally has been classified as a variant of the basal cell carcinoma. More recent evidence favors the classification of FEP as a variant of trichoblastoma. In this case report, we identified a large FEP with benign histologic features suggestive of a follicular origin as demonstrated in part by CK 20 staining and the presence of scattered Merkel cells within the tumor. The pathogenesis of FEP remains enigmatic, and the genetic basis has yet to be fully elucidated. Complete surgical resection is considered curative.
Su
Michael W
MW
University of California Davis, Department of Dermatology, USA.
Fromer
Eric
E
Fung
Maxwell A
MA
D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018862:Merkel Cells / Q000473:pathology; D018225:Neoplasms, Fibroepithelial / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis*