Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pretreatment.
The applicability of capillary zone electrophoresis (CZE) for analysis of cephalosporin antibiotics has been studied in bronchial secretion as highly viscous, thick and non-homogeneous samples. The lyophilization was found to be a simple but effective pretreatment of these samples to bring them into a form which is suitable for injection to CE capillary. The obtained good recovery data prove that the lyophilization/dissolution of bronchial secretion samples can be reproducibly performed.
Andrási
Melinda
M
Department of Inorganic and Analytical Chemistry, University of Debrecen, H-4010 Debrecen, POB 21, Hungary.
Gáspár
Attila
A
Klekner
Almos
A
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000032:analysis*; D001980:Bronchi / Q000378:metabolism*; D002511:Cephalosporins / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D002511:Cephalosporins