title: Liver abscess: a clinicopathological analysis of 82 cases.
abstract: Liver abscesses are a common pathology in India, but a strategy for effective treatment has not been established. Eighty-two patients with liver abscess were studied over a 4-year period. Clinical features, ultrasound findings, laboratory studies, and outcome of therapy were evaluated. Treatment options were antibiotics alone, needle aspiration, catheter drainage, or open surgical drainage; 51.2% of all abscesses were amebic, 23.2% were pyogenic, and 25.6% had unknown causes. A total of 75.6% of the abscesses were solitary, with 62.2% confined to the right lobe. Pyogenic abscesses were more likely to have anemia, leukocytosis, and deranged liver function. Amebic abscesses tended to have a larger volume. Patients undergoing catheter drainage showed a more rapid reduction in initial abscess volume, whereas resolution of the abscess cavity took longer with antibiotic therapy alone. Ultrasound-guided needle aspiration and catheter drainage are safe and effective in the management of liver abscess. Drug therapy alone may be useful only in select cases.
authors.affiliation: Department of Surgery, Lady Hardinge Medical College and Associated Sucheta Kriplani Hospital, New Delhi, India.
authors.forename: Shalabh
authors.initials: S
authors.lastname: Mohan
authors.forename: Nikhil
authors.initials: N
authors.lastname: Talwar
authors.forename: Abhideep
authors.initials: A
authors.lastname: Chaudhary
authors.forename: Manoj
authors.initials: M
authors.lastname: Andley
authors.forename: Bina
authors.initials: B
authors.lastname: Ravi
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar
mesh_terms: D000328:Adult; D000368:Aged; D000563:Amebicides / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004322:Drainage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008101:Liver Abscess, Amebic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D000563:Amebicides; D000900:Anti-Bacterial Agents; D007074:Immunoglobulin G