title: [Acute necrotizing pancreatitis: therapeutic alternatives].
abstract: The management of acute necrotizing pancreatitis has changed significantly over the last few years. Currently, most patients survive the early phases of the disease due to improvements in intensive care unit management. The most important risk factor for morbidity and mortality is infection of the pancreatic necrosis. Ideally, surgery should be delayed until 4 weeks after the onset of symptoms of pancreatitis, as it is at this time that the necrosis is most clearly demarcated. Advances in diagnostic imaging and minimally invasive techniques in surgery and radiology have revolutionized the surgical management of this disease. However, minimally invasive techniques should be limited to critically-ill patients unfit for conventional surgery.
authors.affiliation: Institut Clínic de Malalties Digestives, Departamento de Cirugía, Hospital Clínic i Provincial de Barcelona, Universidad de Barcelona, Barcelona, España. lfcruz@clinic.ub.es
authors.forename: Laureano
authors.initials: L
authors.lastname: Fernández-Cruz
authors.forename: Rubén R
authors.initials: RR
authors.lastname: Lozano-Salazar
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Olvera
authors.forename: Olivia
authors.initials: O
authors.lastname: Higueras
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: López-Boado
authors.forename: Emiliano
authors.initials: E
authors.lastname: Astudillo
authors.forename: Salvador
authors.initials: S
authors.lastname: Navarro
mesh_terms: D000465:Algorithms; D013505:Digestive System Surgical Procedures / Q000379:methods; D006801:Humans; D019283:Pancreatitis, Acute Necrotizing / Q000601:surgery / Q000628:therapy*