Highly efficient Rh(I)-catalyzed asymmetric hydrogenation of enamines using monodente spiro phosphonite ligands.
A highly enantioselective hydrogenation of nonfunctionalized enamines has been developed by using rhodium complexes of chiral spiro phosphonite ligands, providing chiral tertiary amines in excellent enantioselectivities.
Hou
Guo-Hua
GH
State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
Xie
Jian-Hua
JH
Wang
Li-Xin
LX
Zhou
Qi-Lin
QL
D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry; D008024:Ligands; D063065:Organophosphonates / Q000737:chemistry*; D010084:Oxidation-Reduction; D011759:Pyrrolidines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000588:Amines; D001713:Biphenyl Compounds; D008024:Ligands; D063065:Organophosphonates; D011759:Pyrrolidines; D013141:Spiro Compounds; D006859:Hydrogen; D012238:Rhodium