Chromosome segregation: correcting improperly attached chromosomes.
Two new studies show that Aurora B kinase corrects improperly attached chromosomes by recruiting molecules necessary for eliminating the bad attachments and by regulating the turnover of the kinetochore fiber.
Zhang
Xin
X
Medical Sciences, Indiana University, 915 E. 3rd Street, Myers Hall 262, Bloomington, Indiana 47405, USA.
Walczak
Claire E
CE
D000818:Animals; D064127:Aurora Kinases; D020090:Chromosome Segregation / Q000502:physiology*; D018386:Kinetochores / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000502:physiology*
D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases