Radiation-induced brain tumours in nevoid basal cell carcinoma syndrome: implications for treatment and surveillance.
BACKGROUND
We report two cases of radiation-induced intracranial tumours after treatment for medulloblastoma presenting in children with nevoid basal cell carcinoma syndrome.


CONCLUSIONS
These cases illustrate the need for judicious use of post-operative radiotherapy as secondary tumors are commonly reported. This is particularly important as the initial tumour in this cohort is of the 'less aggressive' desmoplastic subtype.
Choudry
Q
Q
Department of Neurosurgery, Royal Preston Hospital, Preston, Lancashire, PR2 9HT, UK. doctorqc2004@yahoo.co.uk
Patel
H C
HC
Gurusinghe
N T
NT
Evans
D G
DG
D000293:Adolescent; D000328:Adult; D001254:Astrocytoma / Q000209:etiology*; D001478:Basal Cell Nevus Syndrome / Q000150:complications / Q000235:genetics / Q000503:physiopathology; D001932:Brain Neoplasms / Q000209:etiology*; D002528:Cerebellar Neoplasms / Q000209:etiology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000209:etiology / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced; D011878:Radiotherapy / Q000009:adverse effects*