A case of subcutaneous phaeohyphomycosis caused by Chaetomium globosum and the sequences analysis of C. globosum.
A 14-year-old boy developed painful erythema and necrosis on his face with petechia on his upper extremities. Microscopically, necrotic tissue treated with potassium hydroxide showed branched, dematiaceous, septate hyphae. Chaetomium globosum was isolated repeatedly from the necrotic tissues. Morphology and thermotolerance test of the pathogen were also studied. The internal transcribed spacer region in rRNA gene was amplified and sequenced. The sequence of this patient matched well with that of C. globosum in GenBank and from other patients and environment.
Yu
Jin
J
Department of Dermatology and Venereology/Research Center for Medical Mycology, Peking University First Hospital, Beijing, PR, China. cindyyu676@hotmail.com
Yang
Shuxia
S
Zhao
Yi
Y
Li
Ruoyu
R
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D002597:Chaetomium / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D021903:DNA, Ribosomal Spacer / Q000032:analysis*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D017422:Sequence Analysis, DNA
D000935:Antifungal Agents; D021903:DNA, Ribosomal Spacer