title: Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pretreatment.
abstract: The applicability of capillary zone electrophoresis (CZE) for analysis of cephalosporin antibiotics has been studied in bronchial secretion as highly viscous, thick and non-homogeneous samples. The lyophilization was found to be a simple but effective pretreatment of these samples to bring them into a form which is suitable for injection to CE capillary. The obtained good recovery data prove that the lyophilization/dissolution of bronchial secretion samples can be reproducibly performed.
authors.affiliation: Department of Inorganic and Analytical Chemistry, University of Debrecen, H-4010 Debrecen, POB 21, Hungary.
authors.forename: Melinda
authors.initials: M
authors.lastname: Andrási
authors.forename: Attila
authors.initials: A
authors.lastname: Gáspár
authors.forename: Almos
authors.initials: A
authors.lastname: Klekner
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000032:analysis*; D001980:Bronchi / Q000378:metabolism*; D002511:Cephalosporins / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins