title: Intense accumulation of gallium-67 citrate in pancreatic endocrine tumor.
abstract: We report intense accumulation of gallium-67 (Ga-67) citrate in a pancreatic endocrine tumor. A 69-year-old woman was admitted because of cough, fever, and weight loss. An abdominal enhanced computed tomography (CT) scan revealed a large tumor located between the liver and pancreas as well as swollen paraaortic lymph nodes. Whole-body scintigraphy with Ga-67 revealed intense accumulation in the upper abdomen corresponding to the mass, as well as in the midabdomen and the mediastinal lesion. Percutaneous needle biopsy was performed, and the diagnosis was adenocarcinoma of the pancreas. The patient's condition deteriorated, and she died 2 months after admission. The pathological examination at autopsy revealed a pancreatic endocrine tumor. No report has described findings of Ga-67 citrate scintigraphy of pancreatic endocrine tumors. Pancreatic endocrine tumor should be included in a differential diagnosis when such scintigraphic findings are encountered.
authors.affiliation: Department of Respiratory Medicine, Maebashi Red Cross Hospital, Maebashi, Gunma 371-0014, Japan. rwatanabe9952@yahoo.co.jp
authors.forename: Rieko
authors.initials: R
authors.lastname: Watanabe
authors.forename: Harunao
authors.initials: H
authors.lastname: Iizuka
authors.forename: Kyoichi
authors.initials: K
authors.lastname: Kaira
authors.forename: Takanori
authors.initials: T
authors.lastname: Mori
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takise
authors.forename: Jun
authors.initials: J
authors.lastname: Ito
authors.forename: Atsushi
authors.initials: A
authors.lastname: Motegi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Onozato
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishihara
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D001707:Biopsy, Needle; D002951:Citrates / Q000378:metabolism*; D017809:Fatal Outcome; D005260:Female; D005708:Gallium / Q000378:metabolism*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
chemical_list: D002951:Citrates; D019275:Radiopharmaceuticals; D005708:Gallium; C103850:gallium citrate