title: Antibacterial activity of a new endodontic sealer against Enterococcus faecalis.
abstract: OBJECTIVE
  The purpose of this study was to test a new root canal sealer (Epiphany) and 5 other root canal sealers (Diaket, Endomethasone, AH 26, Sealapex, Sultan) for their antimicrobial effect on Enterococcus faecalis.
  
  
  METHODS
  The antimicrobial effect of 6 root canal sealers was tested by the agar diffusion method. The freshly mixed sealers were placed in prepared wells of agar plates inoculated with E. faecalis. All plates were incubated for 72 hours at 37 degrees C under aerobic conditions, and zones of inhibition were measured at 24, 48 and 72 hours.
  
  
  RESULTS
  All of the sealers caused bacterial growth inhibition. Their effectiveness, in descending order of antimicrobial activity, was as follows: Endomethasone, Sultan, Sealapex, Diaket, Epiphany and AH 26. Epiphany sealer had little effect on the tested microorganism. The effectiveness of the root canal sealers decreased marginally with greater duration of incubation.
  
  
  CONCLUSIONS
  The Epiphany root canal sealer offered no antibacterial advantage over the other sealers tested.
authors.affiliation: Conservative Dentistry and Endodontics Department, Faculty of Dentistry, Ondokuz Mayis University, 55139 Kurupelit-Samsun/Turkey. bodrumlu@omu.edu.tr
authors.forename: Emre
authors.initials: E
authors.lastname: Bodrumlu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Semiz
mesh_terms: D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects*; D005779:Immunodiffusion; D008422:Materials Testing; D012387:Root Canal Filling Materials / Q000494:pharmacology*
chemical_list: D000891:Anti-Infective Agents, Local; D012387:Root Canal Filling Materials; C486893:epiphany sealer