title: [Metabolic markers of bone--post-guideline].
abstract: Metabolic markers of bone are common clinical parameters for the evaluation of the pathophysiologic conditions and efficacy of the treatment, although they are not helpful for differential diagnosis of osteoporosis. The guideline published officially is helpful for practitioners and non-experts in the field. The distributions of urinary NTX and bone specific alkaline phosphatase are essentially same between primary osteoporotic postmenopausal women less than 70 years old and those over 70 years. No differences were found in the other metabolic markers between these groups. Although clinical evidence for patients over 85 years old is not enough, we do not have to think of age in the clinical application of metabolic markers of bone, if renal functions are within normal ranges.
authors.affiliation: Geriatric Medicine, Graduate School of Medicine, Osaka City University Medical School.
authors.forename: Takami
authors.initials: T
authors.lastname: Miki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000469:Alkaline Phosphatase / Q000032:analysis; D015415:Biomarkers / Q000032:analysis*; D001842:Bone and Bones / Q000378:metabolism*; D024042:Collagen Type I / Q000652:urine; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000378:metabolism*; D010455:Peptides / Q000652:urine
chemical_list: D015415:Biomarkers; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D000469:Alkaline Phosphatase