Parry-Romberg syndrome associated with borreliosis: could photochemotherapy halt the progression of the disease?
Parry-Romberg syndrome (PRS) or progressive hemifacial atrophy is a rare entity characterized by unilateral atrophy of the skin, subcutaneous tissue and sometimes bone and cartilage. Although this syndrome has overlapping features of scleroderma 'en coup de sabre', it shows little or no sclerosis and may affect the entire distribution of the trigeminal nerve including the eye and tongue. As the pathogenesis is unknown, no effective therapy exists. We present here the third case of PRS associated with borreliosis and more interestingly two cases whose progressive course have been stabilized with gel PUVA therapy.
Baskan
Emel Bulbul
EB
Dermatology Department, Uludag University Medical Faculty, Bursa, Turkey. bbemel@uludag.edu.tr
Kaçar
Seval Doğruk
SD
Turan
Ayşegül
A
Saricaoglu
Hayriye
H
Tunali
Sukran
S
Adim
Saduman Balaban
SB
D000328:Adult; D001899:Borrelia Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D005150:Facial Hemiatrophy / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D011701:PUVA Therapy; D012535:Scalp / Q000473:pathology; D014059:Tongue / Q000473:pathology