In vitro prostate cancer cell growth inhibition by Brazilian plant extracts.
In the present study, 1220 plant extracts obtained from 352 plants belonging to 73 families that grow in the Amazon and Atlantic rain forests were screened for cytotoxicity against PC-3 prostate cancer cell lines. Extracts were tested in the single dose of 100 microg/mL. Activity was observed in 17 aqueous or organic extracts belonging to Annonaceae, Apocynaceae, Araceae, Capparaceae, Commelinaceae, Flacourtiaceae, Lecythidaceae, Leguminosae, Passifloraceae, Rutaceae, and Violaceae.
Suffredini
I B
IB
Laboratório de Extração, Universidade Paulista, São Paulo, SP, Brazil. extractlab@unip.br
Paciencia
M L B
ML
Varella
A D
AD
Younes
R N
RN
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001938:Brazil; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D011471:Prostatic Neoplasms / Q000188:drug therapy*
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts