title: Lewis acid mediated regioselective ring opening of benzylglycidol with dibenzyl phosphate: Short and attractive synthesis of dihydroxyacetone phosphate.
abstract: A novel, mild, and efficient method was described to introduce a dibenzyl phosphate by ring opening of benzylglycidol mediated by Lewis acids. This methodology was used as a key step for synthesizing the dihydroxyacetone phosphate (DHAP) in only three steps with an overall yield of 74% from the commercially available racemic benzylglycidol.
authors.affiliation: Université Louis Pasteur, CNR LC3-UMR 7177, Institut Le Bel, 4 rue Blaise Pascal, 67070 Strasbourg Cedex, France.
authors.forename: Odile
authors.initials: O
authors.lastname: Meyer
authors.forename: Sarah
authors.initials: S
authors.lastname: Ponaire
authors.forename: Michel
authors.initials: M
authors.lastname: Rohmer
authors.forename: Catherine
authors.initials: C
authors.lastname: Grosdemange-Billiard