title: Use of Avagard in pediatric urologic procedures.
abstract: OBJECTIVE
  To evaluate the use of Avagard compared with a hand-brush scrub preparation by the urologist in preparation for inpatient and outpatient pediatric urologic operations. Avagard (chlorhexidine gluconate 1% solution and ethyl alcohol 61% wt/wt) is a waterless, brushless, and scrubless hand antiseptic indicated as a replacement for traditional preoperative brush hand scrubbing.
  
  
  METHODS
  We evaluated the first 550 patients for whom we used Avagard as a preoperative hand antiseptic and compared them with the last 550 consecutive patients for whom we performed traditional antiseptic-impregnated hand-brush scrubbing. All patients underwent pediatric urologic procedures. Patients were monitored postoperatively for signs of wound infection, and patients and the surgeon were monitored for side effects. A cost analysis was performed to compare the use of Avagard as a preoperative hand preparation with that of an antiseptic-impregnated hand-brush.
  
  
  RESULTS
  The incidence of wound infection was one in the Avagard group and two in the hand-scrub group, not a statistically significant difference. All wound infections were successfully treated with a single course of oral antibiotics without any long-term sequelae. No side effects for the patients or surgeon were noted, including skin irritations or allergic reactions in either group. The use of Avagard was more time efficient and cost effective.
  
  
  CONCLUSIONS
  To our knowledge, this is the first study demonstrating that Avagard is a fast, effective, easy to apply, and safe surgical hand preparation for pediatric urologic surgery. Its use is cost effective, as well as time efficient, in relation to the traditional surgical scrub.
authors.affiliation: Division of Pediatric Urology, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. jeffrey.palmer@case.edu
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Palmer
mesh_terms: D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D002648:Child; D002710:Chlorhexidine / Q000031:analogs & derivatives*; D000431:Ethanol; D006235:Hand Disinfection / Q000592:standards*; D006801:Humans; D011300:Preoperative Care; D013520:Urologic Surgical Procedures / Q000592:standards*
chemical_list: D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D000431:Ethanol; C010882:chlorhexidine gluconate; D002710:Chlorhexidine