title: Topography of long- and middle-wavelength sensitive cone opsin gene expression in human and Old World monkey retina.
abstract: The topographical distributions of the relative ratio of long- (L) and middle- (M) wavelength sensitive cone opsin messenger RNA (mRNA) in human and baboon retinas were mapped using real-time polymerase chain reaction. The L:M mRNA ratio increased in a central-to-peripheral gradient in both species, being quite pronounced for humans.
authors.affiliation: Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. mneitz@mcw.edu
authors.forename: Maureen
authors.initials: M
authors.lastname: Neitz
authors.forename: Shawn D
authors.initials: SD
authors.lastname: Balding
authors.forename: Carrie
authors.initials: C
authors.lastname: McMahon
authors.forename: Stacy A
authors.initials: SA
authors.lastname: Sjoberg
authors.forename: Jay
authors.initials: J
authors.lastname: Neitz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D015870:Gene Expression / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D048530:Papio anubis; D012333:RNA, Messenger / Q000378:metabolism; D012160:Retina / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D017299:Rod Opsins / Q000235:genetics / Q000378:metabolism*; D012737:Sex Factors
chemical_list: D012333:RNA, Messenger; D017299:Rod Opsins; C095855:long-wavelength opsin; C095854:middle-wavelength opsin