[A case of pulmonary Mycobacterium shimoidei infection].
A 68 year-old male who was ex-smoker presented with fever and cough. Chest radiograph showed infiltrative shadows in both upper lung fields. A sputum smear for acid-fast bacilli was positive. But the isolate was not identified by polymerase chain reaction method. Acid-fast bacilli were cultured from sputum, but the identification was not done by DNA-DNA hybridization method. Mycobacterium shimoidei was identified by 16S ribosomal RNA sequencing with 98.42% matching. Rifampicin, ethambutol, clarithromycin, pyrazinamide, and ciprofloxacin were administered, and the symptom and abnormal shadows on chest radiography improved. And three months later from the initiation of treatment, sputum smear for acid-fast bacilli became negative. Chest CT scan four months after treatments showed decrease of infiltrative shadows. We had treated him for six months, and after that no recurrence occurred.
Takayama
Satoshi
S
Department of Medicine, Yokosuka Kyosai Hospital. tkymablackjack@yahoo.co.jp
Tominaga
Shinichiro
S
Tsukada
Yoshikazu
Y
Ohkochi
Minoru
M
Inase
Naohiko
N
D000368:Aged; D006801:Humans; D008297:Male; D009161:Mycobacterium / Q000302:isolation & purification; D009164:Mycobacterium Infections / Q000382:microbiology*; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*