title: Mixed testicular germ cell tumor presenting as metastatic pure choriocarcinoma involving the maxillary gingiva.
abstract: Gingival metastases are infrequent and invariably associated with a widespread disease and a poor prognosis. Because of their unremarkable clinical appearance, they can be difficult to distinguish from more common gingival hyperplastic or reactive lesions, such as pyogenic granuloma, peripheral giant cell granuloma, and peripheral ossifying granuloma. We are reporting here an unusual case of a 36-year-old man with a mixed testicular germ cell tumor presenting as a metastatic pure choriocarcinoma involving the maxillary gingiva, extending from the first left premolar to the left second maxillary molar, mimicking a 'benign looking' gingival mass. Gingival metastases may be the first manifestation of a widespread metastatic disease and therefore particular attention must be paid to gingival lesions associated with atypical clinical symptoms and/or signs.
authors.affiliation: Division of Oral and Maxillofacial Surgery, University Hospital CHUV, Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Scolozzi
authors.forename: N
authors.initials: N
authors.lastname: Marret
authors.forename: H
authors.initials: H
authors.lastname: Bouzourene
authors.forename: F
authors.initials: F
authors.lastname: Luthi
authors.forename: J
authors.initials: J
authors.lastname: Bauer
authors.forename: B
authors.initials: B
authors.lastname: Jaques
authors.forename: T
authors.initials: T
authors.lastname: Lombardi
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary; D002822:Choriocarcinoma / Q000556:secondary*; D017809:Fatal Outcome; D005887:Gingival Neoplasms / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008437:Maxilla; D018198:Mixed Tumor, Malignant / Q000556:secondary*; D009373:Neoplasms, Germ Cell and Embryonal / Q000556:secondary*; D013736:Testicular Neoplasms