title: A cost-effectiveness analysis of the intrapartum fetal pulse oximetry multicentre randomised controlled trial (the FOREMOST trial).
abstract: OBJECTIVE
  To report an economic analysis of the Australian intrapartum fetal pulse oximetry (FPO) multicentre randomised controlled trial (the FOREMOST trial), which examined whether adding FPO to conventional cardiotocographic (CTG) monitoring (intervention group) was cost-effective in reducing operative delivery rates for non-reassuring fetal status compared with the use of CTG alone (control group).
  
  
  METHODS
  Cost-effectiveness analysis of the FOREMOST trial.
  
  
  METHODS
  Four Australian maternity hospitals, each with more than 4000 births/year.
  
  
  METHODS
  Women in labour at > or =36 weeks of gestation, with a non-reassuring CTG.
  
  
  METHODS
  Costs were for treatment-related expenses, incorporating diagnosis-related grouping costs and direct costs (including fetal monitoring). Incremental cost-effectiveness ratio (ICER) and cost-effectiveness plane were calculated, and sensitivity analysis was conducted. The primary outcome was that of the clinical trial: operative delivery for non-reassuring fetal status avoided in the intervention group relative to that in the control group.
  
  
  METHODS
  The ICER.
  
  
  RESULTS
  The ICER demonstrated a saving of $A813 for each operative birth for non-reassuring fetal status averted by the addition of FPO to CTG monitoring compared with the use of CTG monitoring alone.
  
  
  CONCLUSIONS
  The addition of FPO to CTG monitoring represented a less costly and more effective use of resources to reduce operative delivery rates for non-reassuring fetal status than the use of conventional CTG monitoring alone.
authors.affiliation: Perinatal Research Centre, The University of Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. ceast@somc.uq.edu.au
authors.forename: C E
authors.initials: CE
authors.lastname: East
authors.forename: M B
authors.initials: MB
authors.lastname: Gascoigne
authors.forename: C M
authors.initials: CM
authors.lastname: Doran
authors.forename: S P
authors.initials: SP
authors.lastname: Brennecke
authors.forename: J F
authors.initials: JF
authors.lastname: King
authors.forename: P B
authors.initials: PB
authors.lastname: Colditz
mesh_terms: D000328:Adult; D015148:Cardiotocography / Q000191:economics; D002585:Cesarean Section / Q000191:economics; D003362:Cost-Benefit Analysis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000191:economics* / Q000503:physiopathology; D006331:Heart Diseases / Q000175:diagnosis / Q000191:economics* / Q000503:physiopathology; D006340:Heart Rate, Fetal; D006801:Humans; D010092:Oximetry / Q000191:economics*; D011247:Pregnancy; D012307:Risk Factors