title: Granadaene: proposed structure of the group B Streptococcus polyenic pigment.
abstract: The goal of this work was to determine the chemical nature of the red pigment produced by Streptococcus agalactiae, which has been thought to be a carotene. We extracted the pigment with 0.1 M KOH and purified it by column chromatography on Sephadex LH. Data from elemental analysis and mass and nuclear magnetic resonance spectra lead us to propose the structure to be that of a new ornithine rhamno-polyene with 12 conjugated double bonds, to which we have assigned the trivial name granadaene.
authors.affiliation: Servicio de Microbiología, Hospital Virgen de las Nieves, 18014 Granada, Spain. manuel.rosa.sspa@juntadeandalucia.es
authors.forename: Manuel
authors.initials: M
authors.lastname: Rosa-Fraile
authors.forename: Javier
authors.initials: J
authors.lastname: Rodríguez-Granger
authors.forename: Ali
authors.initials: A
authors.lastname: Haidour-Benamin
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Cuerva
authors.forename: Antonio
authors.initials: A
authors.lastname: Sampedro
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D009952:Ornithine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D010860:Pigments, Biological / Q000737:chemistry* / Q000302:isolation & purification; D011090:Polyenes / Q000737:chemistry* / Q000302:isolation & purification; D013292:Streptococcus agalactiae / Q000737:chemistry*
chemical_list: C578973:(12)-granadaene; D010860:Pigments, Biological; D011090:Polyenes; D009952:Ornithine