title: A patient with early syphilis complicated by fatty liver who showed an alleviation of hepatopathy accompanied by jaundice after receiving anti-syphilitic therapy.
abstract: A 42-year-old male with visceral obesity and a fatty liver presented with hepatopathy accompanied by jaundice and was diagnosed to have early syphilis based on the results of standard serologic tests and clinical findings. Both the subjective and objective findings including hepatopathy were rapidly alleviated by anti-syphilitic therapy. Severe hepatopathy accompanied by jaundice used to be considered a rare complication. However, due to contemporary unhealthy lifestyle patterns characterized by hypernutrition and a lack of exercise the occurrence of fatty liver is now dramatically increasing. Our findings suggest that the occurrence of fatty liver can exacerbate the damage to the hepatic parenchyma due to a Treponema pallidum infection.
authors.affiliation: Department of Internal Medicine, Miyoshi Prefectural Hospital.
authors.forename: Momoko
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Ichiro
authors.initials: I
authors.lastname: Shimizu
authors.forename: Kohzo
authors.initials: K
authors.lastname: Uehara
authors.forename: Soichiro
authors.initials: S
authors.lastname: Fujiwara
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Horie
authors.forename: Arata
authors.initials: A
authors.lastname: Iuchi
authors.forename: Susumu
authors.initials: S
authors.lastname: Ito
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005234:Fatty Liver / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007565:Jaundice / Q000209:etiology*; D008297:Male; D009765:Obesity / Q000150:complications; D013587:Syphilis / Q000150:complications* / Q000188:drug therapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin