title: An easy access to 2-Amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: the reaction under conventional and microwave conditions.
abstract: A new one-stage fast multicomponent synthesis of title compounds leads to products in 21-55% isolated yields under both conventional and microwave conditions. The primary amino group in the building blocks can be easily acylated by various usual electophilic agents that can be utilized in the synthesis of diverse heterocylic compounds libraries.
authors.affiliation: Department of Heterocyclic Compounds, State Scientific Institution,Institute for Single Crystals of National Academy of Sciences of Ukraine, Kharkiv, Ukraine. gorobets@isc.kharkov.com
authors.forename: Konstantin S
authors.initials: KS
authors.lastname: Ostras
authors.forename: Nikolay Yu
authors.initials: NY
authors.lastname: Gorobets
authors.forename: Sergey M
authors.initials: SM
authors.lastname: Desenko
authors.forename: Vladimir I
authors.initials: VI
authors.lastname: Musatov
mesh_terms: D020650:Combinatorial Chemistry Techniques; D006361:Heating; D008872:Microwaves; D015394:Molecular Structure; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011744:Pyrimidinones