title: Highly efficient Rh(I)-catalyzed asymmetric hydrogenation of enamines using monodente spiro phosphonite ligands.
abstract: A highly enantioselective hydrogenation of nonfunctionalized enamines has been developed by using rhodium complexes of chiral spiro phosphonite ligands, providing chiral tertiary amines in excellent enantioselectivities.
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Hou
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Xie
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Wang
authors.forename: Qi-Lin
authors.initials: QL
authors.lastname: Zhou
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry; D008024:Ligands; D063065:Organophosphonates / Q000737:chemistry*; D010084:Oxidation-Reduction; D011759:Pyrrolidines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000588:Amines; D001713:Biphenyl Compounds; D008024:Ligands; D063065:Organophosphonates; D011759:Pyrrolidines; D013141:Spiro Compounds; D006859:Hydrogen; D012238:Rhodium