title: Mutation of His-157 in the second pore loop drastically reduces the activity of the Synechocystis Ktr-type transporter.
abstract: Mutation of a conserved His-157 in the second pore loop of KtrB drastically reduced the activity of the K+ transporter from Synechocystis sp. strain PCC 6803. This result suggests that His-157 plays an essential role in the K+ transport activity of the transporter system.
authors.affiliation: Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Japan.
authors.forename: Lalu
authors.initials: L
authors.lastname: Zulkifli
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Uozumi
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D027682:Cation Transport Proteins / Q000235:genetics / Q000378:metabolism*; D002412:Cations / Q000378:metabolism; D006639:Histidine / Q000235:genetics / Q000502:physiology*; D008969:Molecular Sequence Data; D017354:Point Mutation; D011188:Potassium / Q000378:metabolism*; D016415:Sequence Alignment; D046939:Synechocystis / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D027682:Cation Transport Proteins; D002412:Cations; C113206:KtrB protein, Bacteria; D006639:Histidine; D011188:Potassium