title: Relevance of influenza a virus detection by PCR, shell vial assay, and tube cell culture to rapid reporting procedures.
abstract: Influenza A virus was detected at higher rates and for more extended time periods with real-time PCR than with cell cultures. We show here that, using the theranostic approach, rapid viral detection and reporting can provide for early implementation and assessment of available antiviral therapy.
authors.affiliation: Division of Clinical Microbiology, Mayo Clinic, 200 1st St., SW, Rochester, MN 55905, USA.
authors.forename: Nicole L
authors.initials: NL
authors.lastname: Zitterkopf
authors.forename: Surbhi
authors.initials: S
authors.lastname: Leekha
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Espy
authors.forename: Christina M
authors.initials: CM
authors.lastname: Wood
authors.forename: Priya
authors.initials: P
authors.lastname: Sampathkumar
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002460:Cell Line; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D009980:Influenza A virus / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology; D016133:Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D013997:Time Factors; D014776:Virus Cultivation / Q000295:instrumentation / Q000379:methods
chemical_list: D004279:DNA, Viral