title: Migraine prophylaxis: who, why, and how.
abstract: If a patient has frequent, severely debilitating migraine headaches, prophylactic treatment may help. Beta-blockers, tricyclic antidepressants, and anticonvulsants have the best evidence of efficacy; calcium channel blockers and nonsteroidal anti-inflammatory drugs are also popular because they are well tolerated and inexpensive. We review migraine treatment with emphasis on prophylaxis.
authors.affiliation: Department of Medicine, Advocate Lutheran General Hospital, Park Ridge, IL 60068, USA.
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Loj
authors.forename: Glen D
authors.initials: GD
authors.lastname: Solomon
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D018890:Chemoprevention / Q000592:standards; D004876:Ergot Alkaloids / Q000627:therapeutic use; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control*; D013997:Time Factors; D014363:Tryptamines / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000927:Anticonvulsants; D000928:Antidepressive Agents; D004876:Ergot Alkaloids; D014363:Tryptamines