Prenatally diagnosed sacrococcygeal teratoma: a prognostic classification.
OBJECTIVE
The objective of this study is to describe a prognostic classification for prenatally diagnosed sacrococcygeal teratoma (SCT).


METHODS
Charts from 44 fetuses were reviewed. Three groups were defined as follows: group A--tumor diameter less than 10 cm, absent or mild vascularity and slow growth; group B--diameter 10 cm or greater, pronounced vascularity or high-output cardiac failure and fast growth; group C--diameter 10 cm or greater, predominantly cystic lesion with absent or mild vascularity and slow growth.


RESULTS
Size at diagnosis, growth rate, and vascularity were higher in group B. Gestational age at delivery was lower in group B. Eleven of 21 died in the perinatal period in group B and none in groups A and C. In group C, drainage or shunting of the SCT has been performed in 6 of 10 cases.


CONCLUSIONS
Group A is associated to good maternal and perinatal outcome, as well as group C, although shunting or drainage of the SCT could be necessary. Large fast-growing SCT with rich vascularity is associated with a higher perinatal mortality and morbidity than smaller lesions with mild vascularity.
Benachi
Alexandra
A
Maternité, Hôpital Necker-Enfants Malades AP-HP-Université Paris V, 149 rue de Sèvres, 75743 Paris Cedex 15, France. alexandra.benachi@nck.ap-hop-paris.fr
Durin
Luc
L
Vasseur Maurer
Sabine
S
Aubry
Marie-Cécile
MC
Parat
Sophie
S
Herlicoviez
Michel
M
Nihoul-Fekete
Claire
C
Dumez
Yves
Y
Dommergues
Marc
M
D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D012445:Sacrococcygeal Region; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality / Q000601:surgery; D013724:Teratoma / Q000000981:diagnostic imaging* / Q000401:mortality / Q000601:surgery; D016216:Ultrasonography, Prenatal