title: Surface and biocidal activity of some synthesized metallo azobenzene isothiouronium salts.
abstract: A novel series of azobenzene isothiouronium salts of different alkyl chains (propyl, hexyl and dodecyl) were synthesized by reaction of 4-((4-methylphenyl)azo)phenol with 1,3-dibromopropane, 1,6-dibromohexane and 1,12-dibromododecane, respectively. These salts were reacted with copper (II) halide to give their corresponding metallo complexes. The surface tension measurements for the synthesized compounds show that the metallo complexes have adsorption and micellization better than that of the parent azobenzene isothiouronium salts. The pathogenic Gram-negative bacteria, Gram-positive bacteria, fungi and yeast were used to determine the biocidal activity of these compounds using gradient plate technique. The results indicate that the copper complexes of the synthesized azobenzene isothiouronium salts have a relatively better biocidal activity than the parent salts.
authors.affiliation: Egyptian Petroleum Research Institute, Applied Surfactants Laboratory, Petrochemicals Department, Cairo, Egypt.
authors.forename: A M
authors.initials: AM
authors.lastname: Badawi
authors.forename: E M S
authors.initials: EM
authors.lastname: Azzam
authors.forename: S M I
authors.initials: SM
authors.lastname: Morsy
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D003300:Copper / Q000737:chemistry*; D005658:Fungi / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007550:Isothiuronium / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008823:Micelles; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012492:Salts; D013500:Surface Tension
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001391:Azo Compounds; D008823:Micelles; D012492:Salts; D007550:Isothiuronium; D003300:Copper; C009850:azobenzene