title: Geometric comparison of aortic bifurcation prostheses to the normal and atherosclerotic human aorta, and clinical trial of a vertical seamed bifurcation prosthesis.
abstract: The 12 bifurcation prostheses generally available in the United States were compared. One was woven Teflon, two woven Dacron, and nine knitted Dacron. Ten were "seamless" in construction, and two were "seamed," but close examination revealed that all prostheses actually were seamed at the bifurication point. The grafts varied considerably in construction, porosity, and geometry. To compare the geometries, each prosthesis was preclotted in plasma, inflated to 120 mm. Hg, and quick frozen in alcohol and dry ice. Transverse and frontal bisections of the frozen specimens were photographed with a millimeter scale for sizing. For comparison, eight human aortofemoral bifurcations were distended and frozen similarly. The prostheses had far wider bifurcation shelves than did the normal aortas. The five normal human aortofemoral bifurcations had an average ratio of limb: body diameter of 0.61; the three atherosclerotic specimens averaged 0.49. The prostheses had an average limb:body diameter ratio of 0.48. or the "seamless" grafts, 0.48 for the circular transverse limb-seamed grafts, and 0.58 for the vertical-seamed grafts. Vertical-seamed aortic bifurcation grafts implanted in 102 patients between 1970 and 1976 (average follow-up, 29.5 months) have developed only a single limb closure, at 53 months.
authors.affiliation: Reconstructive Cardiovascular Research Center of Providence Medical Center, Wash 98122, USA.
authors.forename: L R
authors.initials: LR
authors.lastname: Sauvage
authors.forename: S B
authors.initials: SB
authors.lastname: Robel
authors.forename: S J
authors.initials: SJ
authors.lastname: Wood
authors.forename: S G
authors.initials: SG
authors.lastname: Yates
authors.forename: M A
authors.initials: MA
authors.lastname: O'Brien
authors.forename: J C
authors.initials: JC
authors.lastname: Smith
authors.forename: C C
authors.initials: CC
authors.lastname: Davis
authors.forename: D G
authors.initials: DG
authors.lastname: Hall
authors.forename: P B
authors.initials: PB
authors.lastname: Mansfield
mesh_terms: D001011:Aorta / Q000033:anatomy & histology / Q000601:surgery*; D001018:Aortic Diseases / Q000601:surgery*; D050197:Atherosclerosis / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D002986:Clinical Trials as Topic; D006801:Humans