[Study on primary hepatocellular carcinoma associated with hypersplenism treated by partial splenic embolization combined with hepatic arterial chemoembolization].
OBJECTIVE
70-90% of patients of primary hepatocellular carcinoma (PHC) are associated with liver cirrhosis, portal hypertension and hypersplenism. The treatment of PHC is usually hampered by low or slow recovery of blood cell counts. This study was to investigate the effect of partial splenic embolization (PSE) combined with transcatheter hepatic arterial chemoembolization (TACE) for the treatment of PHC with portal hypertension and hypersplenism.


METHODS
Efficacy of 26 patients with PSE combined with TACE and 26 patients with single TACE was observed.


RESULTS
Satisfactory effects were achieved in PSE combined with TACE group in terms of correction of blood cell counts compared with cases treated with TACE alone.


CONCLUSIONS
PSE associated with TACE is safe and effective for the treatment of patients with PHC associated with liver cirrhosis, portal hypertension and hypersplenism.
Huang
Jin-Hua
JH
Department of Imaging and Interventional Radiology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China. huangjhmd@yahoo.com
Wu
Pei-Hong
PH
Gu
Yang-Kui
YK
Zhang
Fu-Jun
FJ
Li
Chuan-Xing
CX
Gao
Fei
F
Zhang
Liang
L
Fan
Wei-Jun
WJ
Li
Chang-Jiang
CJ
D000328:Adult; D001772:Blood Cell Count; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000098:blood supply / Q000150:complications / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D006971:Hypersplenism / Q000097:blood / Q000150:complications / Q000628:therapy*; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000097:blood / Q000098:blood supply / Q000150:complications / Q000628:therapy*; D008297:Male; D013157:Splenic Artery
D007459:Iodized Oil