Preliminary FMRI evidence of visual system dysfunction in Parkinson's disease patients with visual hallucinations.
Using functional magnetic resonance imaging (fMRI), the authors examined visual cortex function in Parkinson's disease patients who did and did not experience visual hallucinations. Patients with visual hallucinations demonstrated increased activation in the visual association cortex and deficits in the primary visual cortex, suggesting that visual hallucinations are associated with an abnormality of visual-cortex function.
Holroyd
Suzanne
S
Department of Psychiatric Medicine, University of Virginia Health System, Box 800623, Charlottesville, VA 22908, USA. sh4s@virginia.edu
Wooten
G Frederick
GF
D000368:Aged; D005260:Female; D006212:Hallucinations / Q000209:etiology* / Q000473:pathology* / Q000523:psychology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000473:pathology* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D014786:Vision Disorders / Q000209:etiology* / Q000473:pathology*; D014787:Vision Tests; D014793:Visual Cortex / Q000473:pathology