title: Complications in mammalian microRNA target prediction.
abstract: In this chapter, we review evidence that at least three different types of microRNA (miRNA)-messenger RNA (mRNA) target interactions exist in mammals: short seeds, long seeds, and "perfect" hits (allowing G:U matches). Because new types of miRNAs are still being discovered, this list may not yet be complete.
authors.affiliation: Department of Psychiatry and UIC Psychiatric Institute, University of Illinois-Chicago, IL, USA.
authors.forename: Neil R
authors.initials: NR
authors.lastname: Smalheiser
authors.forename: Vetle I
authors.initials: VI
authors.lastname: Torvik
mesh_terms: D020413:3' Untranslated Regions; D000818:Animals; D030541:Databases, Genetic; D020224:Expressed Sequence Tags; D020084:Long Interspersed Nucleotide Elements; D008322:Mammals / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D035683:MicroRNAs / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D034622:RNA Interference; D012333:RNA, Messenger / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012984:Software
chemical_list: D020413:3' Untranslated Regions; D035683:MicroRNAs; D012333:RNA, Messenger