title: Projection-based bolus detection for computed tomographic angiography.
abstract: Computed tomographic (CT) angiography is important for imaging studies on cardiovascular structures, peripheral vessels, and solid organs. In practice, a CT angiography scan is triggered by the bolus arrival at a prespecified anatomical location, which is determined using CT fluoroscopy. In this article, we propose a projection-based method adapted from the Grangeat formula to detect the bolus arrival. Then, we evaluate our new method in numerical and animal studies. Our results indicate that this method allows significantly better temporal resolution and is computationally more efficient, as compared with the image-based methods.
authors.affiliation: CT/Micro-CT Laboratory, Department of Radiology, University of Iowa, Iowa City, IA, USA. donghuilu@ct.radiology.uiowa.edu
authors.forename: Donghui
authors.initials: D
authors.lastname: Lu
authors.forename: Erwei
authors.initials: E
authors.lastname: Bai
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.forename: Hengyong
authors.initials: H
authors.lastname: Yu
authors.forename: Yuchuan
authors.initials: Y
authors.lastname: Wei
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Cai
authors.forename: Melhem J
authors.initials: MJ
authors.lastname: Sharafuddin
authors.forename: Jafar
authors.initials: J
authors.lastname: Golzarian
authors.forename: Alan
authors.initials: A
authors.lastname: Stolpen
authors.forename: Osama
authors.initials: O
authors.lastname: Saba
authors.forename: Michael
authors.initials: M
authors.lastname: Vannier
authors.forename: Ge
authors.initials: G
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000379:methods; D000818:Animals; D003287:Contrast Media; D005471:Fluoroscopy / Q000379:methods; D008168:Lung / Q000000981:diagnostic imaging; D008962:Models, Theoretical; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012756:Sheep; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media