title: [Treatment of malignant ovarian tumours in Georgia in 1990-2000].
abstract: The adequate treatment of ovary tumor and the issue of improvement of subsequent results still remain the urgent question of oncology. In 60-80% of diseased the pathology appears at the final--the third and the forth i.e. later stages, while the prolongation of life for the five years period is quite rare--13-47%. Our aim is to study the effectiveness of treatment of malignant ovary tumor based on the data of 1990-2000 provided by A. Gvamichava National Oncological Centre, to develop optimal methods of treatment and select the right tactics in order to improve subsequent results for patients with malignant ovary tumor. The research revealed that the epithelial neoplasm (malignant ovary tumor) is 5.2 times more spread than nonepithelial (malignant ovary tumor). In our clinic the preference is given to the operational method combined with further chemotherapy (ch/t) for treatment of malignant ovary tumor. The advantage is given to the radical surgery (59.4%), amputation of uterine appendages and omentum resection (79.3%). In the case of less radical surgery (23%)--amputation of uterine appendages (63.8%), while for non-radical surgery (17.5%)--ovariectomy, omentum resection (60%). The number of radical surgery of epithelial neoplasm 3 times exceeds less radical surgery and 12 times--non-radical surgery, while in the case of non epithelial neoplasm the number of radical surgery is two times more than less radical surgery and 3 times more than that non radical. In 1990-2000 in the National Oncological Centre ch/t without platinum and audrioblastin (44.8%) had been most frequently used for treatment of ovary tumor. The main schemes were: cyclophosphan + phtoruracyle and cyclophosphan + phtoruracyle +metotrexat.
authors.forename: T A
authors.initials: TA
authors.lastname: Zurabiani
authors.forename: L I
authors.initials: LI
authors.lastname: Charkviani
authors.forename: G K
authors.initials: GK
authors.lastname: Gersamia
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D002277:Carcinoma / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005846:Georgia (Republic); D006801:Humans; D007044:Hysterectomy; D008727:Methotrexate / Q000008:administration & dosage; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery*; D010052:Ovariectomy; D016896:Treatment Outcome
chemical_list: D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate