title: Metastatic atypical choroid plexus papilloma: a case report.
abstract: Choroid plexus papillomas (CPPs) are rare adult tumours and metastatic disease is even less common, more typically associated with choroid plexus carcinoma. We present the case of a 32-year-old patient with multiple metastases arising along the length of the neuraxis 3 years after resection of an atypical fourth ventricular CPP. Metastatic deposits were found from the mid-brain to the lumbar cistern and the patient underwent repeat excision of the fourth ventricular tumour, partial resection of a cervico-thoracic deposit and craniospinal radiotherapy. Possible explanations for the rarity of atypical CPP include unclear diagnostic criteria leading to under-representation in reported cases. We review the current literature on metastatic CPP and discuss the role of surgery and adjuvant therapy in relation to both typical and atypical disease.
authors.affiliation: Department of Neurosurgery, Royal Free Hospital, Hampstead, London, UK. chrisuff@hotmail.com
authors.forename: Christopher E G
authors.initials: CE
authors.lastname: Uff
authors.forename: Malcolm
authors.initials: M
authors.lastname: Galloway
authors.forename: Robert
authors.initials: R
authors.lastname: Bradford
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D020546:Fourth Ventricle / Q000473:pathology; D005910:Glioma / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D020288:Papilloma, Choroid Plexus / Q000473:pathology* / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000556:secondary* / Q000601:surgery