Synthesis of platinum(II) chiral tetraamine coordination complexes.
The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches were found to best afford the title compounds.
Nefzi
Adel
A
Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, California 92121, USA.
Hoesl
Cornelia E
CE
Pinilla
Clemencia
C
Kauffman
George B
GB
Maggiora
Gerald M
GM
Pasquale
Elena
E
Houghten
Richard A
RA
D020650:Combinatorial Chemistry Techniques; D017672:Nitrogen Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D017671:Platinum Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D013237:Stereoisomerism
D017672:Nitrogen Compounds; D017671:Platinum Compounds; D012996:Solutions; C086333:tetraammineplatinum(II)