Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature.
1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90 degrees C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90 degrees C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90 degrees C for at least two weeks.
Yoshida
Yayoi
Y
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Kimura
Yukitaka
Y
Kadota
Megumi
M
Tsuno
Takuo
T
Adachi
Shuji
S
D019149:Bioreactors; D003373:Coumaric Acids / Q000737:chemistry / Q000378:metabolism*; D004800:Enzymes, Immobilized / Q000378:metabolism*; D005656:Fungal Proteins; D019850:Heptanol / Q000737:chemistry; D000441:Hexanols / Q000737:chemistry; D008049:Lipase / Q000378:metabolism*; D000439:Pentanols / Q000737:chemistry; D012995:Solubility
D003373:Coumaric Acids; D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D000441:Hexanols; D000439:Pentanols; C036260:1-hexanol; D019850:Heptanol; C004999:ferulic acid; D008049:Lipase; C431349:lipase B, Candida antarctica; C024999:n-pentanol