title: The relationships among clinician delay of diagnosis of breast cancer and tumor size, nodal status, and stage.
abstract: BACKGROUND
  The objective of this study was to determine the impact of delay of diagnosis by clinicians on breast cancer prognostic factors and survival.
  
  
  METHODS
  The medical records of patients whose breast cancer diagnosis was delayed by clinicians were reviewed. Data collected included primary tumor diameter, number of positive lymph nodes, tumor grade, pathologic stage, length of diagnostic delay, and follow-up status. Data were analyzed for correlations between prognostic factors and length of delay. The Fisher exact test was used to correlate delay and stage with survival.
  
  
  RESULTS
  Forty patients had delays from 3 to 36 months. There were no significant correlations between delay and natural log of primary tumor diameter (r = -.16, P = .33), number of positive lymph nodes (r = .22, P = .90), tumor grade (R = -.16, P = .36), or pathologic stage (R = -.09, P = .59). A higher stage correlated with decreased survival (P = .03), but delay did not.
  
  
  CONCLUSIONS
  Clinician diagnostic delays of up to 36 months did not correlate with worsening prognostic factors or with survival rates.
authors.affiliation: Division of Surgical Oncology, Department of General Surgery, Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd., L223A, Portland, OR 97201, USA.
authors.forename: Chelsea
authors.initials: C
authors.lastname: Hardin
authors.forename: Suellen
authors.initials: S
authors.lastname: Pommier
authors.forename: Rodney F
authors.initials: RF
authors.lastname: Pommier
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D003951:Diagnostic Errors / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors