title: Sarcomatoid carcinoma and orbital apex syndrome.
abstract: OBJECTIVE
  To report a case of sarcomatoid carcinoma and orbital apex syndrome in a previously healthy adult.
  
  
  METHODS
  A previously healthy 45-year-old man presented with exophthalmos of the left eye and a mass visible through his left nostril. A biopsy was performed and immunohistochemistry was used to confirm the diagnosis of the tumor. The patient was treated with chemotherapy and radiotherapy.
  
  
  RESULTS
  After treatment, we observed a substantial reduction in the size of the mass, but side effects of treatment developed. The visual acuity of the left eye was no light perception. Eight months later, the patient presented with bone and liver metastases, and he died 4 months later.
  
  
  CONCLUSIONS
  Sarcomatoid carcinoma is an aggressive tumor that can produce compressive symptoms with very poor visual and survival prognoses. A cranio-orbital computed tomography scan should be performed when patients present with symptoms of conjunctivitis and orbital apex syndrome.
authors.affiliation: Department of Ophthalmology, University Clinic of Navarra, University of Navarra, Avda/Pio XII 36, 31008 Pamplona (Navarre), Spain. lmsadaba@unav.es
authors.forename: L M
authors.initials: LM
authors.lastname: Sadaba
authors.forename: A
authors.initials: A
authors.lastname: García-Layana
authors.forename: P J
authors.initials: PJ
authors.lastname: Garcia-Gomez
authors.forename: A
authors.initials: A
authors.lastname: Salinas-Alaman
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001859:Bone Neoplasms / Q000556:secondary; D002296:Carcinosarcoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009896:Optic Atrophy / Q000473:pathology*; D009916:Orbital Diseases / Q000473:pathology*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D013577:Syndrome; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor