title: Radiation-induced brain tumours in nevoid basal cell carcinoma syndrome: implications for treatment and surveillance.
abstract: BACKGROUND
  We report two cases of radiation-induced intracranial tumours after treatment for medulloblastoma presenting in children with nevoid basal cell carcinoma syndrome.
  
  
  CONCLUSIONS
  These cases illustrate the need for judicious use of post-operative radiotherapy as secondary tumors are commonly reported. This is particularly important as the initial tumour in this cohort is of the 'less aggressive' desmoplastic subtype.
authors.affiliation: Department of Neurosurgery, Royal Preston Hospital, Preston, Lancashire, PR2 9HT, UK. doctorqc2004@yahoo.co.uk
authors.forename: Q
authors.initials: Q
authors.lastname: Choudry
authors.forename: H C
authors.initials: HC
authors.lastname: Patel
authors.forename: N T
authors.initials: NT
authors.lastname: Gurusinghe
authors.forename: D G
authors.initials: DG
authors.lastname: Evans
mesh_terms: D000293:Adolescent; D000328:Adult; D001254:Astrocytoma / Q000209:etiology*; D001478:Basal Cell Nevus Syndrome / Q000150:complications / Q000235:genetics / Q000503:physiopathology; D001932:Brain Neoplasms / Q000209:etiology*; D002528:Cerebellar Neoplasms / Q000209:etiology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000209:etiology / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced; D011878:Radiotherapy / Q000009:adverse effects*