title: Intermittent hepatic vein balloon occlusion during radiofrequency ablation in the liver.
abstract: The purpose of the study was to assess the feasibility of intermittent hepatic vein balloon occlusion during percutaneous radiofrequency (RF) ablation. Eight non-anticoagulated patients who had primary (n = 2) and metastatic (n = 6) liver tumors with a mean diameter of 4.2 cm (range 2.4-6.5 cm) were treated, resulting in a mean ablation diameter of 6.3 cm (range 4.3-9.3 cm). Six of 9 (67%) of the balloon-occluded hepatic veins were patent. No clinical sequelae of thrombosis were noted. Mean length of follow-up with CT and/or MRI was 12 months. Local tumor control was achieved in 5 of 8 patients. Intermittent hepatic vein balloon occlusion could potentially be a low-risk adjunctive maneuver for thermal ablation therapy in the treatment of large tumors and tumors adjacent to large vessels.
authors.affiliation: Department of Radiology, National Institutes of Health, Warren G. Magnuson Clinical Center, Building 10, Room 1C660, Bethesda, MD 20892, USA.
authors.forename: Deepak
authors.initials: D
authors.lastname: Sudheendra
authors.forename: Ziv
authors.initials: Z
authors.lastname: Neeman
authors.forename: Anthony
authors.initials: A
authors.lastname: Kam
authors.forename: Julia
authors.initials: J
authors.lastname: Locklin
authors.forename: Steven K
authors.initials: SK
authors.lastname: Libutti
authors.forename: Bradford J
authors.initials: BJ
authors.lastname: Wood
mesh_terms: D000368:Aged; D021721:Balloon Occlusion / Q000379:methods; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006503:Hepatic Veins; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome