title: Proton thrusters: overview of the structural and functional features of soluble tetrahaem cytochromes c3.
abstract: Tetrahaem cytochromes c (3) from sulfate-reducing bacteria have revealed exquisite complexity in their ligand binding properties and they couple the cooperative binding of two electrons with the binding of protons. In this review, the molecular mechanisms for these cooperative effects are described, and the functional consequences of these cooperativities are discussed in the context of the general mechanisms of biological energy transduction and the specific physiological metabolism of Desulfovibrio.
authors.affiliation: Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal. louro@itqb.unl.pt
authors.forename: Ricardo O
authors.initials: RO
authors.lastname: Louro
mesh_terms: D003574:Cytochrome c Group / Q000737:chemistry* / Q000502:physiology*; D003901:Desulfovibrio / Q000737:chemistry / Q000378:metabolism; D004579:Electron Transport; D004735:Energy Transfer; D008024:Ligands; D008954:Models, Biological; D010084:Oxidation-Reduction; D011487:Protein Conformation; D011522:Protons
chemical_list: D003574:Cytochrome c Group; D008024:Ligands; D011522:Protons; C017165:cytochrome c(3)