title: Unusual macular lesions in a patient with neurofibromatosis type-1.
abstract: BACKGROUND
  Retinal involvement in neurofibromatosis type-1 (NF-1) is rare.
  
  
  METHODS
  We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity.
  
  
  RESULTS
  Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions.
  
  
  CONCLUSIONS
  Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.
authors.affiliation: Department of Ophthalmology, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. eibhlin_mcloone@hotmail.com
authors.forename: Eibhlín M
authors.initials: EM
authors.lastname: McLoone
authors.forename: Trevor A S
authors.initials: TA
authors.lastname: Buchanan
mesh_terms: D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D019572:Retinal Neoplasms / Q000175:diagnosis*; D014792:Visual Acuity