Hydrocephalus associated with Guillain-Barre syndrome.
A 68-year-old man developed progressive four-limb weakness and areflexia 17 days after an influenza vaccination. He was diagnosed with Guillain-Barre syndrome (GBS), and remained ventilator dependent and bed-bound for 3 months, despite plasmapheresis and immunoglobulin infusion. However, cognitive impairment, excessive daytime sleepiness, and motor disability were still present, even when he was no longer ventilator dependent. Brain computerized tomography scan and isotope cisternography was consistent with normal pressure hydrocephalus. His motor control and cognitive function recovered almost completely after insertion of a ventriculoperitoneal shunt. Although hydrocephalus is not frequently associated with GBS, our case report indicates that brain imaging is necessary in GBS patients whose cognitive functions deteriorates after disease onset.
Liu
Chih-Yang
CY
Neurological Institute, Taipei Veterans General Hospital, Peitou District, Taipei, Taiwan.
Kao
Chuen-Der
CD
Chen
Jen-Tse
JT
Yeh
Yu-Shu
YS
Wu
Zin-An
ZA
Liao
Kwong-Kum
KK
D000368:Aged; D000465:Algorithms; D003072:Cognition Disorders / Q000209:etiology; D020275:Guillain-Barre Syndrome / Q000150:complications*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D007252:Influenza Vaccines / Q000009:adverse effects; D008297:Male; D011011:Pneumoencephalography; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt
D007252:Influenza Vaccines