title: Enantioselective conjugate radical addition to alpha'-hydroxy enones.
abstract: Enantioselective conjugate radical addition to alpha'-hydroxy alpha,beta-unsaturated ketones, compounds containing bidentate donors, has been investigated. It has been found that radical additions to alpha'-hydroxy alpha,beta-unsaturated ketones in the presence of Mg(NTf2)2 and bisoxazoline ligand 5a proceeded cleanly, yielding the addition products in high chemical yields and good enantiomeric excesses.
authors.affiliation: Center for Molecular Design & Synthesis and Department of Chemistry, School of Molecular Science (BK-21), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
authors.forename: Sunggi
authors.initials: S
authors.lastname: Lee
authors.forename: Chae Jo
authors.initials: CJ
authors.lastname: Lim
authors.forename: Sunggak
authors.initials: S
authors.lastname: Kim
authors.forename: Rajesh
authors.initials: R
authors.lastname: Subramaniam
authors.forename: Jake
authors.initials: J
authors.lastname: Zimmerman
authors.forename: Mukund P
authors.initials: MP
authors.lastname: Sibi
mesh_terms: D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007659:Ketones