title: Thick maximum intensity projections for the assessment of left ventricular function with 64-slice computed tomography.
abstract: OBJECTIVE
  The objective of this study was to assess the accuracy of thick maximum intensity projections (MIP) from computed tomography (CT) data sets mimicking projection images from biplane ventriculography for evaluation of left ventricular (LV) parameters.
  
  
  METHODS
  Fifty-eight patients underwent 64-slice CT. Multiphase images were reconstructed in 10% steps of the RR interval. MIP images (70-mm thickness) of the contrast-enhanced LV in fixed 30 degrees right anterior oblique (RAO)/60 degrees left anterior oblique (LAO) and in adapted short-/long-axis planes were reconstructed. LV parameters were calculated using the area-length method formula. Three-dimensional assessment with semiautomated software served as reference standard.
  
  
  RESULTS
  Use of thick MIP reconstructions had a high intermethod reliability (86-94%) compared with the 3-dimensional approach. Smaller measurement errors were found for thick MIP reconstructions in adapted short-/long-axis planes. A significant projection error (3.0%, P < 0.001) of thick MIP reconstructions was found using fixed 30 degrees RAO/60 degrees LAO compared with adapted short-/long-axis reconstructions.
  
  
  CONCLUSIONS
  Thick MIP reconstructions with adapted short-/long-axis planes allow an accurate assessment of LV parameters compared with the established 3-dimensional method.
authors.affiliation: Institute of Diagnostic Radiology, University of Zurich, Zurich, Switzerland.
authors.forename: Lars
authors.initials: L
authors.lastname: Husmann
authors.forename: Sebastian
authors.initials: S
authors.lastname: Leschka
authors.forename: Lotus
authors.initials: L
authors.lastname: Desbiolles
authors.forename: Tiziano
authors.initials: T
authors.lastname: Schepis
authors.forename: Pascal
authors.initials: P
authors.lastname: Koepfli
authors.forename: Oliver
authors.initials: O
authors.lastname: Gaemperli
authors.forename: Burkhardt
authors.initials: B
authors.lastname: Seifert
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Flohr
authors.forename: Thomas
authors.initials: T
authors.lastname: Frauenfelder
authors.forename: Borut
authors.initials: B
authors.lastname: Marincek
authors.forename: Philipp A
authors.initials: PA
authors.lastname: Kaufmann
authors.forename: Hatem
authors.initials: H
authors.lastname: Alkadhi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*