title: Versatile, fragrant, convertible isonitriles.
abstract: The metalation of oxazoles leads to ring opening to the isocyanoenolate that can be O-acylated to give the unsaturated isonitriles. These substances undergo conventional multicomponent reactions. The products of their reactions are readily converted to acyl substitution products by treatment with acid and a nucleophile. These unsaturated isonitriles are notable by their simple preparations and, unusually, their nonoffensive odors.
authors.affiliation: Department of Chemistry, University of California, Riverside, California 92521, USA. michael.pirrung@ucr.edu
authors.forename: Michael C
authors.initials: MC
authors.lastname: Pirrung
authors.forename: Subir
authors.initials: S
authors.lastname: Ghorai