title: Cavitary Legionella pneumonia in a patient with immunodeficiency due to Hyper-IgE syndrome.
abstract: We report about a 35-year-old man with a cavitary legionella pneumonia who had a history of chronic eczematoid lesions since infancy, recurrent skin and lung infections and a very high total IgE level. We carried out further investigations and made a diagnosis of a primary immunodeficiency classified in the Hyper-IgE syndromes. Cavitation of legionella pneumonia may become fairly common in immunocompromised patients, while is found rarely among immunocompetent hosts.
authors.affiliation: Department of Internal Medicine, Respiratory Medicine Unit, Immunology and Allergology Unit, University G. d'Annunzio, Chieti, Italy. f.distefano@aliceposta.it <f.distefano@aliceposta.it>
authors.forename: Fabio
authors.initials: F
authors.lastname: Di Stefano
authors.forename: Nicola
authors.initials: N
authors.lastname: Verna
authors.forename: Mario
authors.initials: M
authors.lastname: Di Gioacchino
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004485:Eczema; D006801:Humans; D007589:Job Syndrome / Q000150:complications*; D016952:Legionella pneumophila / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D011859:Radiography
chemical_list: D000900:Anti-Bacterial Agents