title: Comparison of the degenerative changes in weight-bearing joints following cementing or grafting techniques in giant cell tumour patients: medium-term results.
abstract: The aim of this retrospective study was to compare and assess the effect of bone grafting and cementing techniques--two common applications used in the treatment of subchondral giant cell tumours of bone (GCTs)--on the development of degenerative changes in the weight-bearing joints of the lower extremity. Eighty patients were included in this follow-up study, 44 of whom underwent curettage followed by bone grafting, and 36 who had curettage followed by cementation. At the 24-month post-operative examination, significantly less degenerative change was found in patients with bone cement than in those with bone grafting. At the 50-month and later (range: 50-148 months) post-operative examination, however, no significant differences were found between the two groups, indicating that there was a significant acceleration of degenerative changes in the cemented group after the 24-month follow-up.
authors.affiliation: Orthopaedic Clinic of Semmelweis University, Budapest, Hungary. krisztian.szalay@gmail.com
authors.forename: K
authors.initials: K
authors.lastname: Szalay
authors.forename: I
authors.initials: I
authors.lastname: Antal
authors.forename: J
authors.initials: J
authors.lastname: Kiss
authors.forename: M
authors.initials: M
authors.lastname: Szendroi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000534:rehabilitation / Q000601:surgery*; D016025:Bone Transplantation / Q000009:adverse effects*; D018572:Disease-Free Survival; D005269:Femur / Q000473:pathology; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000534:rehabilitation / Q000601:surgery*; D006801:Humans; D007596:Joints / Q000473:pathology*; D053208:Kaplan-Meier Estimate; D008875:Middle Aged; D011788:Quality of Life; D020127:Recovery of Function; D012189:Retrospective Studies; D013977:Tibia / Q000473:pathology; D016474:Weight-Bearing
chemical_list: D001843:Bone Cements