title: Use of solid-phase microextraction to detect and quantify gas-phase dicarbonyls in indoor environments.
abstract: Solid-phase microextraction (SPME) was evaluated for the detection and quantification of the gas-phase dicarbonyls, glyoxal (GLY) and methylglyoxal (MGLY). Additionally, polydimethylsiloxane (PDMS), polydimethylsiloxane/divinylbenzene (PDMS/DVB), and carbowax/divinylbenzene (CW/DVB) fibers were tested to determine the optimum fiber for detection of these species. GLY and MGLY were derivatized with O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA), extracted with SPME from headspace or bag chamber and then analyzed by GC/MS. The PDMS/DVB SPME fiber for on-fiber derivatization and subsequent sampling for gas-phase methylglyoxal provided the optimum combination of analytical reproducibility and sensitivity. Linearity of the calibration curve was achieved across a range of 11-222 microg/m(3) (4-75 ppb).
authors.affiliation: Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA.
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Pacolay
authors.forename: Jason E
authors.initials: JE
authors.lastname: Ham
authors.forename: J R
authors.initials: JR
authors.lastname: Wells
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D016902:Air Pollution, Indoor / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006037:Glyoxal / Q000032:analysis*; D011765:Pyruvaldehyde / Q000032:analysis*; D015203:Reproducibility of Results; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D000393:Air Pollutants; D006037:Glyoxal; D011765:Pyruvaldehyde