Occurrence of thioredoxin reductase in Deinococcus species, the UV resistant bacteria.
The occurrence of thioredoxin reductase (NAD(P)H: oxidized-thioredoxin reductase, EC 1.6.4.5, TrxR) in five mesophilic species of Deinococcus was investigated by PAGE. Each species possessed a unique TrxR pattern, for example, a single TrxR characterized D. radiopugnans while multiple forms of TrxR occurred in other Deinococcal spp. Most of TrxRs occurring in Deinococcus showed dual cofactor specificity, active with either NADH or NADPH, although the NADPH specific-TrxR was observed in D. radiophilus and D.proteolyticus.
Seo
Hee Jeong
HJ
Division of Life Sciences, Research Institute for Basic Research, Chungbuk National University, Cheongju, Chungbuk 361-763, Republic of Korea.
Lee
Young Nam
YN
D034301:Deinococcus / Q000145:classification / Q000201:enzymology*; D004591:Electrophoresis, Polyacrylamide Gel; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D018384:Oxidative Stress; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D013880:Thioredoxin-Disulfide Reductase / Q000737:chemistry / Q000378:metabolism*; D014466:Ultraviolet Rays
D012336:RNA, Ribosomal, 16S; D009243:NAD; D009249:NADP; D013880:Thioredoxin-Disulfide Reductase