Desmoplastic infantile ganglioglioma with calcification.
Desmoplastic infantile gangliogliomas (DIGs) are rare intracranial, cystic tumors, usually detected within the first 2 years of life. Histologically, these tumors are characterized by intense desmoplasia and a divergent astrocytic and neuronal differentiation. Less than 60 well-documented cases of this extremely rare tumor are reported in the literature. We present the case of a 10-month-old male child presenting with a large, cystic, intracranial lesion and having the characteristic histological features of a DIG. In addition, the lesion also showed focal areas of calcification within the tumor, not usually considered a feature of this entity. The present case extends the reported spectrum of this rare entity and describes the unusual occurrence of calcification within the lesion.
Bhardwaj
Minakshi
M
Department of Pathology, Dr Ram Manohar Lohia Hospital, New Delhi, India. minakshi58@yahoo.co.in
Sharma
Alok
A
Pal
Hillol K
HK
D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D002114:Calcinosis / Q000473:pathology*; D019299:Decompression, Surgical; D003937:Diagnosis, Differential; D018303:Ganglioglioma / Q000473:pathology* / Q000601:surgery; D005910:Glioma / Q000473:pathology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures