title: The protective effect of TiF4, SnF2 and NaF on erosion of enamel by hydrochloric acid in vitro measured by white light interferometry.
abstract: The purpose of this in vitro study was to compare the protective effect of TiF4, SnF2 and NaF (all 0.5 M F) on the development of erosion-like lesions in human dental enamel. Four enamel specimens from each of 6 extracted molars were polished and embedded in epoxy resin. The enamel surfaces of 3 specimens from each tooth were treated with the different fluoride solutions for 2 min. Following fluoride treatments, the specimens were immersed in 0.01 M HCl (pH 2.0), for 2, 4 and 6 min in order to mimic a gastric reflux situation. One specimen from each tooth was used as a control and was only exposed to acid. The etching depths (in micrometres) after 6 min were: TiF4 0.8 (SD 0.8), SnF2 3.5 (SD 0.7), NaF 5.3 (SD 0.4), and 7.0 (SD 0.3) for the control specimens. Compared to the control, TiF(4) protected the enamel surface from acid attack almost completely (88%), while SnF2 reduced the etch depth after 6 min by 50% and NaF by 25%.
authors.affiliation: Faculty of Dentistry,University of Oslo, Oslo, Norway. lenehh@odont.uio.no
authors.forename: L
authors.initials: L
authors.lastname: Hove
authors.forename: B
authors.initials: B
authors.lastname: Holme
authors.forename: B
authors.initials: B
authors.lastname: Øgaard
authors.forename: T
authors.initials: T
authors.lastname: Willumsen
authors.forename: A B
authors.initials: AB
authors.lastname: Tveit
mesh_terms: D000704:Analysis of Variance; D003743:Dental Enamel / Q000187:drug effects; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D006851:Hydrochloric Acid / Q000009:adverse effects; D007368:Interferometry; D008963:Molar; D012969:Sodium Fluoride / Q000627:therapeutic use*; D014002:Tin Fluorides / Q000627:therapeutic use*; D014025:Titanium / Q000627:therapeutic use*; D014077:Tooth Erosion / Q000517:prevention & control*
chemical_list: D014002:Tin Fluorides; D012969:Sodium Fluoride; D014025:Titanium; D005459:Fluorides; D006851:Hydrochloric Acid; C032240:titanium tetrafluoride