title: Anaphylaxis to cefazolin during labor secondary to prophylaxis for group B Streptococcus: a case report.
abstract: BACKGROUND
  Anaphylaxis is an uncommon event during pregnancy, but if it does arise, it can lead to serious fetal consequences even if there are no serious long-term maternal complications.
  
  
  METHODS
  A parturient developed anaphylaxis in the labor unit shortly after intravenous cefazolin chemoprophylaxis had begun for perinatal group B streptococcal disease. Prompt treatment for anaphylaxis commenced, involving the administration of epinephrine and glucocorticoids, and an emergency cesarean section spared the mother serious morbidity, with a favorable perinatal outcome for the fetus.
  
  
  CONCLUSIONS
  To the best of our knowledge, this case is the first reported one of anaphylaxis to cefazolin in pregnancy secondary to prophylaxis against for B Streptococcus. The case demonstrates that a life-threatening anaphylactic reaction can occur at any time during pregnancy and that all staff in a maternal unit should be familiar with the management of perinatal anaphylaxis.
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, 5, Fu-Shin Street, Kwei-Shan, Tao-Yuan, 333 Taiwan, ROC.
authors.forename: Mei-Shan
authors.initials: MS
authors.lastname: Jao
authors.forename: Po-Jen
authors.initials: PJ
authors.lastname: Cheng
authors.forename: Sheng-Wen
authors.initials: SW
authors.lastname: Shaw
authors.forename: Yung-Kuei
authors.initials: YK
authors.lastname: Soong
mesh_terms: D000328:Adult; D000707:Anaphylaxis; D000900:Anti-Bacterial Agents / Q000276:immunology* / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D002437:Cefazolin / Q000276:immunology* / Q000627:therapeutic use; D002585:Cesarean Section; D004630:Emergencies; D005260:Female; D006801:Humans; D007744:Obstetric Labor Complications / Q000139:chemically induced* / Q000276:immunology; D011247:Pregnancy; D011256:Pregnancy Outcome; D013290:Streptococcal Infections / Q000188:drug therapy / Q000517:prevention & control*; D013292:Streptococcus agalactiae
chemical_list: D000900:Anti-Bacterial Agents; D002437:Cefazolin