In vitro inhibitory activity of boropinic acid against Helicobacter pylori.
In this study, we assessed in vitro minimum inhibitory concentration (MIC) values of some natural geranyloxycoumarins, geranyloxy- and isopentenyloxy acids against growth of Helicobacter pylori. Boropinic acid, active principle isolated from Boronia pinnata (Fam. Rutaceae), was seen to be the most effective compound with a MIC value of 1.62 microg/mL.
Epifano
Francesco
F
Dipartimento di Scienze del Farmaco, Via dei Vestini 31, 66013 Chieti Scalo (CH), Italy. fepifano@unich.it
Menghini
Luigi
L
Pagiotti
Rita
R
Angelini
Paola
P
Genovese
Salvatore
S
Curini
Massimo
M
D002264:Carboxylic Acids / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects*; D027821:Rutaceae
D002264:Carboxylic Acids