title: Mechanisms ensuring optimal conditions of implantation and embryo development in the pig.
abstract: The paper summarizes results of a series of studies concerning luteolysis and early pregnancy in pigs. The involvement of the oxytocin (OT)/OT receptor system in the mechanism of corpus luteum (CL) protection during early pregnancy as well as the implication of luteinizing hormone (LH) in the endometrial prostaglandin (PG) release and synthesis are described. In addition, the role of leptin in the regulation of ovarian steroidogenesis and the expression of leptin and its receptor (OB-Rb) genes in hypothalamus, pituitary and reproductive tissues are reported. Moreover, a strong emphasis was placed on the mechanism of PGE2 participation in the local endocrine regulations of reproductive processes occurring in the utero-ovarian area as well as on the vascular endothelial growth factor (VEGF) ligand-receptor system in the ovary and uterus.
authors.affiliation: Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-718 Olsztyn, Poland. jadwigap@uwm.edu.pl
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Przała
authors.forename: Ewa L
authors.initials: EL
authors.lastname: Gregoraszczuk
authors.forename: Genowefa
authors.initials: G
authors.lastname: Kotwica
authors.forename: Stanisława
authors.initials: S
authors.lastname: Stefańczyk-Krzymowska
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Ziecik
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Blitek
authors.forename: Anna
authors.initials: A
authors.lastname: Ptak
authors.forename: Anna
authors.initials: A
authors.lastname: Rak
authors.forename: Anna
authors.initials: A
authors.lastname: Wójtowicz
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Kamiński
authors.forename: Gabriela
authors.initials: G
authors.lastname: Siawrys
authors.forename: Nina
authors.initials: N
authors.lastname: Smolińska
authors.forename: Anita
authors.initials: A
authors.lastname: Franczak
authors.forename: Beata
authors.initials: B
authors.lastname: Kurowicka
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Oponowicz
authors.forename: Barbara
authors.initials: B
authors.lastname: Wasowska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Chłopek
authors.forename: Anna E
authors.initials: AE
authors.lastname: Kowalczyk
authors.forename: Monika M
authors.initials: MM
authors.lastname: Kaczmarek
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Wacławik
mesh_terms: D000818:Animals; D003338:Corpus Luteum / Q000378:metabolism; D015237:Dinoprost / Q000378:metabolism; D015232:Dinoprostone / Q000378:metabolism; D010064:Embryo Implantation / Q000502:physiology*; D047108:Embryonic Development / Q000502:physiology*; D030762:Estrous Cycle / Q000378:metabolism; D005260:Female; D020738:Leptin / Q000378:metabolism / Q000502:physiology; D007986:Luteinizing Hormone / Q000502:physiology; D010053:Ovary / Q000378:metabolism; D011247:Pregnancy; D013552:Swine / Q000502:physiology*; D014599:Uterus / Q000378:metabolism
chemical_list: D020738:Leptin; D007986:Luteinizing Hormone; D015237:Dinoprost; D015232:Dinoprostone