title: Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis.
abstract: Tbx2 belongs to the T-box transcription factor gene family and is expressed in a variety of tissues and structures throughout development, although not all expression domains have been thoroughly described. Two areas of segmented expression along the rostral-caudal axis of E10.5-11.5 embryos were identified as inter-somitic vessels and dorsal root ganglia. In addition, Tbx2 expression is observed during somitogenesis beginning at E9.5, both in the posterior half of prospective somites and in a progressively restricted pattern in recently formed somites.
authors.affiliation: Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, New York, USA.
authors.forename: Zachary
authors.initials: Z
authors.lastname: Harrelson
authors.forename: Virginia E
authors.initials: VE
authors.lastname: Papaioannou
mesh_terms: D000818:Animals; D047108:Embryonic Development / Q000235:genetics; D051379:Mice; D008813:Mice, Inbred ICR; D019170:Somites / Q000737:chemistry / Q000378:metabolism*; D020825:T-Box Domain Proteins / Q000032:analysis / Q000378:metabolism*; D014157:Transcription Factors / Q000032:analysis / Q000378:metabolism*
chemical_list: C097348:T-Box Domain Protein 2; D020825:T-Box Domain Proteins; D014157:Transcription Factors