Neither LKB1 nor AMPK are the direct targets of metformin.
Hardie
David Grahame
DG
D055372:AMP-Activated Protein Kinases; D000818:Animals; D003920:Diabetes Mellitus / Q000201:enzymology / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D008687:Metformin / Q000494:pharmacology*; D051379:Mice; D009097:Multienzyme Complexes / Q000187:drug effects / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000187:drug effects / Q000378:metabolism*; D051381:Rats
D007004:Hypoglycemic Agents; D009097:Multienzyme Complexes; D008687:Metformin; D017346:Protein Serine-Threonine Kinases; D055372:AMP-Activated Protein Kinases