title: Human development IV: the living cell has information-directed self-organisation.
abstract: In this paper, restricted to describe the ontogenesis of the cell, we discuss the processing of DNA through RNA to proteins and argue that this process is not able to transfer the information necessary to organize the proteins in the cell, but only to transfer the information necessary to form the shape of the proteins. We shortly describe the structure of the information carrying field recruited by the cells that we think is responsible for building the organelles and other cellular structures. We use the cells superior control of its cytoskeleton as an example of how the cell is using an informational field giving the positional information guiding all the local chemical processes behind the cell movement. We describe the information-directed self-organization in cells and argue that this can explain the ontogenesis of the cell. We also suggest the existence of an undiscovered phenomenon behind the information transmitting cell interactions. We conclude that during evolution the cell has developed into an information-guided self-organizing structure. The mystery we want to solve is: what is the mechanical cause and nature of biological information?
authors.affiliation: Quality of Life Research Center, Teglgårdstraede 4-8, DK-1452 Copenhagen K, Denmark. ventegodt@livskvalitet.org
authors.forename: Søren
authors.initials: S
authors.lastname: Ventegodt
authors.forename: Tyge Dahl
authors.initials: TD
authors.lastname: Hermansen
authors.forename: Trine
authors.initials: T
authors.lastname: Flensborg-Madsen
authors.forename: Maj Lyck
authors.initials: ML
authors.lastname: Nielsen
authors.forename: Birgitte
authors.initials: B
authors.lastname: Clausen
authors.forename: Joav
authors.initials: J
authors.lastname: Merrick
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism; D002465:Cell Movement; D002468:Cell Physiological Phenomena; D006803:Human Development; D006801:Humans; D015388:Organelles / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism
chemical_list: D011506:Proteins