Two new 15-deoxycimigenol-type and three new 24-epi-cimigenol-type glycosides from Cimicifuga Rhizome.
Two new 15-deoxycimigenol-type (1, 2) and three new 24-epi-cimigenol-type glycosides (3-5) were isolated from Cimicifuga Rhizome, and the structures were elucidated on the basis of spectroscopic data including 2D NMR spectra and chemical evidence. The two new 15-deoxycimigenol-type glycosides were the first cimigenol-type glycosides lacking a hydroxyl group at C-15.
Yoshimitsu
Hitoshi
H
Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 862-0082, Japan. hyoshimi@ph.sojo-u.ac.jp
Nishida
Makiko
M
Sakaguchi
Masahide
M
Nohara
Toshihiro
T
D031885:Cimicifuga / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008968:Molecular Conformation; D012015:Reference Standards; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
C514036:15-deoxycimigenol; C514035:24-epi-cimigenol; D006027:Glycosides