title: The CarA/LitR-family transcriptional regulator: Its possible role as a photosensor and wide distribution in non-phototrophic bacteria.
abstract: LitR is a MerR-family regulator that controls light-induced carotenogenesis in Streptomyces coelicolor. The introduction of litR conferred photo-dependent transcription activities on Streptomyces griseus, which does not perform photo-responsive carotenogenesis. LitR discovers homologs encoded at illumination-related loci of various non-phototrophic bacterial genomes. Probably, LitR acts not only as a transcriptional regulator but also a photosensor.
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takano
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Beppu
authors.forename: Kenji
authors.initials: K
authors.lastname: Ueda
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D008027:Light; D008543:Melanins / Q000096:biosynthesis; D016296:Mutagenesis; D048372:Streptomyces coelicolor / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D013305:Streptomyces griseus / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D014169:Transformation, Bacterial
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; D008543:Melanins; C051124:MerR protein, Bacteria