title: Association of a single dose of gonadotropin-releasing hormone antagonist with nitric oxide and embryo quality in in vitro fertilization cycles.
abstract: The patients undertaking a single-dose protocol for GnRH antagonist were associated with elevated serum and follicular levels of nitric oxide (NO) and decreased embryo quality scores compared with those who underwent the long protocol for GnRH agonist. The relatively poor embryo quality may be NO related instead of Fas related.
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Tsung-Hsien
authors.initials: TH
authors.lastname: Lee
authors.forename: Ming-Yih
authors.initials: MY
authors.lastname: Wu
authors.forename: Hsin-Fu
authors.initials: HF
authors.lastname: Chen
authors.forename: Shee-Uan
authors.initials: SU
authors.lastname: Chen
authors.forename: Hong-Nerng
authors.initials: HN
authors.lastname: Ho
authors.forename: Yu-Shih
authors.initials: YS
authors.lastname: Yang
mesh_terms: D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006727:Hormone Antagonists / Q000008:administration & dosage*; D006801:Humans; D009569:Nitric Oxide / Q000097:blood*; D006080:Ovarian Follicle / Q000166:cytology / Q000187:drug effects / Q000378:metabolism
chemical_list: D006727:Hormone Antagonists; D009569:Nitric Oxide; D007987:Gonadotropin-Releasing Hormone