title: [Image-guided radiotherapy by in-room CT-linear accelerator combination].
abstract: Target localization has become increasingly important in the advent of IMRT, as treatment margins are reduced and target doses are increased with high-dose gradients outside this target volume. The in-room CT on rails-LINAC system allows CT imaging while the patient remains immobilized in the treatment position just prior to treatment. The anatomic inter- and intra-fractional variations can be therefore quantified during a course of treatment. The position of the tumour can be checked and corrected before the fraction. In case of modification of tumour shape, a re-planning of the treatment is also feasible. However, several issues remain: the integration with routine clinical treatment due to a lack of software tools, the frequency of imaging, and the cost-efficiency ratio. The clinical experience is yet very limited but CT-image-guided radiotherapy appears promising for prostate, brain and spinal tumours.
authors.affiliation: Département de radiothérapie, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif, France.
authors.forename: R
authors.initials: R
authors.lastname: de Crevoisier
authors.forename: D
authors.initials: D
authors.lastname: Kuban
authors.forename: D
authors.initials: D
authors.lastname: Lefkopoulos
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated; D013125:Spinal Neoplasms / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed / Q000379:methods*