title: Cushing's paraneoplastic syndrome as first manifestation of an adenocarcinoma of unknown origin.
abstract: Small cell lung cancer is the most common cause of paraneoplastic Cushing's syndrome. The definitive treatment consists in surgical removal of the tumour, which is not possible in most of these cases (they are often diagnosed at advanced stages), and therefore it is frequently necessary adding the drug ketoconazol. We hereby present the case of a patient diagnosed with a metastatic carcinoma of unknown origin associated with two paraneoplastic syndromes: a Cushing's syndrome and a sensitive-motor axonal neuropathy, a very uncommon association.
authors.affiliation: Servicio de Oncología Médica, Hospital General Universitario de Elche, Alicante, Spain. mjmolinagarrido@hotmail.com
authors.forename: María José
authors.initials: MJ
authors.lastname: Molina Garrido
authors.forename: Carmen
authors.initials: C
authors.lastname: Guillén Ponce
authors.forename: Sonia
authors.initials: S
authors.lastname: Maciá Escalante
authors.forename: Vanesa
authors.initials: V
authors.lastname: Pons Sanz
authors.forename: Alfredo
authors.initials: A
authors.lastname: Carrato Mena
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000209:etiology*; D000230:Adenocarcinoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis*; D020364:Paraneoplastic Polyneuropathy / Q000209:etiology*