title: Quantum dot encapsulation in viral capsids.
abstract: Incorporation of CdSe/ZnS semiconductor quantum dots (QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly(ethylene glycol) (PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.
authors.forename: Suraj K
authors.initials: SK
authors.lastname: Dixit
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Goicochea
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Daniel
authors.forename: Ayaluru
authors.initials: A
authors.lastname: Murali
authors.forename: Lyudmila
authors.initials: L
authors.lastname: Bronstein
authors.forename: Mrinmoy
authors.initials: M
authors.lastname: De
authors.forename: Barry
authors.initials: B
authors.lastname: Stein
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Rotello
authors.forename: C Cheng
authors.initials: CC
authors.lastname: Kao
authors.forename: Bogdan
authors.initials: B
authors.lastname: Dragnea
mesh_terms: D002213:Capsid / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D015336:Molecular Probe Techniques; D036103:Nanotechnology / Q000379:methods*; D045663:Quantum Dots; D019065:Virus Assembly
chemical_list: D020099:Coated Materials, Biocompatible