title: An efficient synthesis and biological activity of substituted p-benzoquinones.
abstract: An efficient synthesis of 2,5-diarylamino-3,6-dichloro-1,4-benzoquinone derivatives has been achieved by condensing mono substituted anilines with tetrachloro-p-benzoquinone in presence of fused sodium acetate as condensing agent under microwave irradiation without any solvent. All the synthesized compounds were tested for their antibacterial and antitumour activity using standard drugs.
authors.affiliation: Department of Pure and Applied Chemistry, Maharshi Dayanand Saraswati University, Ajmer 305 009, India. manojbatra05@rediffmail.com
authors.forename: Manoj
authors.initials: M
authors.lastname: Batra
authors.forename: Prashant
authors.initials: P
authors.lastname: Kriplani
authors.forename: Chhavi
authors.initials: C
authors.lastname: Batra
authors.forename: K G
authors.initials: KG
authors.lastname: Ojha
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D016227:Benzoquinones / Q000138:chemical synthesis* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000188:drug therapy*; D051379:Mice; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014407:Tumor Cells, Cultured
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D016227:Benzoquinones; C004532:quinone