title: Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B(1) in rats.
abstract: In this study, the modulation of aflatoxin B(1) (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.
authors.affiliation: Department of Clinical Nutrition, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland. silvia.gratz@uku.fi
authors.forename: S
authors.initials: S
authors.lastname: Gratz
authors.forename: M
authors.initials: M
authors.lastname: Täubel
authors.forename: R O
authors.initials: RO
authors.lastname: Juvonen
authors.forename: M
authors.initials: M
authors.lastname: Viluksela
authors.forename: P C
authors.initials: PC
authors.lastname: Turner
authors.forename: H
authors.initials: H
authors.lastname: Mykkänen
authors.forename: H
authors.initials: H
authors.lastname: El-Nezami
mesh_terms: D016604:Aflatoxin B1 / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D000818:Animals; D005243:Feces / Q000737:chemistry; D007408:Intestinal Absorption / Q000502:physiology*; D052201:Lacticaseibacillus rhamnosus; D019936:Probiotics / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D015430:Weight Gain
chemical_list: D016604:Aflatoxin B1