title: Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion.
abstract: The effect of beta-alanine (beta-Ala) alone or in combination with creatine monohydrate (Cr) on aerobic exercise performance is unknown. The purpose of this study was to examine the effects of 4 weeks of beta-Ala and Cr supplementation on indices of endurance performance. Fifty-five men (24.5 +/- 5.3 yrs) participated in a double-blind, placebo-controlled study and randomly assigned to one of 4 groups; placebo (PL, n = 13), creatine (Cr, n = 12), beta-alanine (beta-Ala, n = 14), or beta-alanine plus creatine (CrBA, n = 16). Prior to and following supplementation, participants performed a graded exercise test on a cycle ergometer to determine VO(2peak), time to exhaustion (TTE), and power output, VO(2), and percent VO(2peak) associated with VT and LT. No significant group effects were found. However, within groups, a significant time effect was observed for CrBa on 5 of the 8 parameters measured. These data suggest that CrBA may potentially enhance endurance performance.
authors.affiliation: Department of Exercise Science and Health Promotion, Florida Atlantic University, Davie, FL, USA. rzoeller@fau.edu
authors.forename: R F
authors.initials: RF
authors.lastname: Zoeller
authors.forename: J R
authors.initials: JR
authors.lastname: Stout
authors.forename: J A
authors.initials: JA
authors.lastname: O'kroy
authors.forename: D J
authors.initials: DJ
authors.lastname: Torok
authors.forename: M
authors.initials: M
authors.lastname: Mielke
mesh_terms: D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology*; D003401:Creatine / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D019587:Dietary Supplements; D004311:Double-Blind Method; D016552:Ergometry; D015444:Exercise; D005080:Exercise Test; D006801:Humans; D008297:Male; D018763:Muscle Fatigue; D010101:Oxygen Consumption; D010807:Physical Endurance / Q000187:drug effects*; D010919:Placebos; D013647:Task Performance and Analysis; D015091:beta-Alanine / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D010919:Placebos; D015091:beta-Alanine; D003401:Creatine