Hereditary neuropathy with liability to pressure palsy combined with schwannomas of the median and medial plantar nerves.
A 42-year-old woman was surgically treated for carpal tunnel syndrome, revealing schwannoma of the median nerve. A year later, she developed a tarsal tunnel syndrome. At time of this diagnosis, hereditary neuropathy with liability to pressure palsies (HNPP) was diagnosed genetically and a schwannoma of the medial plantar nerve was treated surgically. The occurrence of HNPP and schwannomas in the same patient might be purely coincidental, but it is tempting to speculate that they share a common genetic basis.
Heckmann
Josef G
JG
Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, D-91054 Erlangen, Germany. josef.heckmann@neuro.imed.uni-erlangen.de
Dütsch
Matthias
M
Buslei
Ralf
R
D000328:Adult; D002349:Carpal Tunnel Syndrome / Q000150:complications / Q000235:genetics / Q000503:physiopathology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D015417:Hereditary Sensory and Motor Neuropathy / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D006801:Humans; D008475:Median Nerve / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D020423:Median Neuropathy / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D009408:Nerve Compression Syndromes / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D009442:Neurilemmoma / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D013641:Tarsal Tunnel Syndrome / Q000150:complications / Q000235:genetics / Q000503:physiopathology; D013979:Tibial Nerve / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D020429:Tibial Neuropathy / Q000150:complications* / Q000235:genetics / Q000503:physiopathology