title: Commissioning of a conformal irradiation system for heavy-ion radiotherapy using a layer-stacking method.
abstract: The commissioning of conformal radiotherapy system using heavy-ion beams at the Heavy Ion Medical Accelerator in Chiba (HIMAC) is described in detail. The system at HIMAC was upgraded for a clinical trial using a new technique: large spot uniform scanning with conformal layer stacking. The system was developed to localize the irradiation dose to the target volume more effectively than with the old system. With the present passive irradiation method using a ridge filter, a scatterer, a pair of wobbler magnets, and a multileaf collimator, the width of the spread-out Bragg peak (SOBP) in the radiation field could not be changed. With dynamic control of the beam-modifying devices during irradiation, a more conformal radiotherapy could be achieved. In order to safely perform treatments with this conformal therapy, the moving devices should be watched during irradiation and the synchronousness among the devices should be verified. This system, which has to be safe for patient irradiations, was constructed and tested for safety and for the quality of the dose localization realized. Through these commissioning tests, we were successfully able to prepare the conformal technique using layer stacking for patients. Subsequent to commissioning the technique has been applied to patients in clinical trials.
authors.affiliation: Department of Medical Physics, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan. kanai@nirs.go.jp
authors.forename: Tatsuaki
authors.initials: T
authors.lastname: Kanai
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kanematsu
authors.forename: Shinichi
authors.initials: S
authors.lastname: Minohara
authors.forename: Masataka
authors.initials: M
authors.lastname: Komori
authors.forename: Masami
authors.initials: M
authors.lastname: Torikoshi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Asakura
authors.forename: Noritoshi
authors.initials: N
authors.lastname: Ikeda
authors.forename: Takayuki
authors.initials: T
authors.lastname: Uno
authors.forename: Yuka
authors.initials: Y
authors.lastname: Takei
mesh_terms: D002138:Calibration; D004867:Equipment Design; D019544:Equipment Failure Analysis; D063193:Heavy Ion Radiotherapy; D007564:Japan; D011785:Quality Assurance, Health Care / Q000379:methods* / Q000592:standards*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000379:methods / Q000592:standards*