[The role of some pituitary hormones in patients with non-insulin-dependent diabetes mellitus and diabetic retinopathy].
The level of somatotropin and thyreotropin hormones was measured in blood plasma of patients with non-insulin-dependent diabetes mellitus with and without diabetic retinopathy (DR). Fifty eight patients (26 males and 32 females) aged from 35 to 75 were examined. The patients were divided into two groups. First group included 29 patients (13 males and 16 females) with non-insulin-dependent diabetes mellitus without DR. Second group included the same number of patients with non-insulin-dependent diabetes mellitus complicated by DR. The concentration of somatotropin hormones was increased and thyreotropin was decreased in patients with non-insulin-dependent diabetes mellitus with DR. The results suggest that somatotropin and thyreotropin contributes to the development of diabetic retinopathy in humans.
Dundua
T T
TT
Sumbadze
Ts M
TsM
Dzhodzhua
T D
TD
Papava
M V
MV
D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003930:Diabetic Retinopathy / Q000209:etiology*; D005260:Female; D019382:Human Growth Hormone / Q000097:blood / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010907:Pituitary Hormones / Q000097:blood / Q000502:physiology; D013972:Thyrotropin / Q000097:blood / Q000502:physiology*
D015415:Biomarkers; D010907:Pituitary Hormones; D019382:Human Growth Hormone; D013972:Thyrotropin