Directed molecular recognition: design and synthesis of neutral receptors for biotin to bind both its functional groups.
The neutral receptors 1 and 2 are designed and synthesized for the recognition of biotin, a biologically significant molecule, in chloroform to bind completely both of its functional groups simultaneously, i.e., cyclic urea and the carboxyl groups. The truncated receptor 3 binds only the cyclic urea moiety.
Goswami
Shyamaprosad
S
Department of Chemistry, Bengal Engineering and Science University, Shibpur, Howrah-711 103, West Bengal, India. spgoswamical@yahoo.com
Dey
Swapan
S
D001665:Binding Sites; D001710:Biotin / Q000031:analogs & derivatives / Q000032:analysis / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008958:Models, Molecular; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
D011725:Pyridines; D001710:Biotin