[Polymorphism of the locus HUMHUU in the Polish population--a preliminary report].
The paper presents the results of a population study on the locus HUMHUU, which is a non-coding fragment of human DNA built of four nucleotide repeats (CTTT)n, localized on the 16th chromosome. The studies, carried out on a group of 200 non-related individuals, showed the presence of 14 different alleles, from 150 to 200 bp in length. Biostatistical calculations demonstrated that the expected heterozygosity was 0,830301 +/- 0,018768, PD - 0,949156, PIC - 0,806888, PE - 0,662444, PE for motherless cases - 0,491305, and the average paternity index - 2,946389. The results obtained during the studies of the locus HUMHUU allow for recognizing it as a marker of personal identification useful for the needs of both criminalistics and disputed paternity testing.
Konarzewska
Magdalena
M
Wydziału Biologii Centralnego Laboratorium Kryminalistycznego Komendy Glównej Policji.
Spólnicka
Magdalena
M
Sołtyszewski
Ireneusz
I
Berent
Jarosław
J
D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D016172:DNA Fingerprinting / Q000379:methods*; D005819:Genetic Markers; D005820:Genetic Testing / Q000379:methods; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D011044:Poland; D011110:Polymorphism, Genetic; D015203:Reproducibility of Results; D012463:Saliva; D012680:Sensitivity and Specificity; D017422:Sequence Analysis, DNA / Q000379:methods*; D020080:Tandem Repeat Sequences / Q000235:genetics*
D005819:Genetic Markers