title: Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia.
abstract: OBJECTIVE
  To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia.
  
  
  METHODS
  Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia.
  
  
  METHODS
  Private Infertility clinic.
  
  
  METHODS
  None, charts review.
  
  
  METHODS
  None, charts review.
  
  
  METHODS
  Clinical pregnancy rate (PR), implantation rate.
  
  
  RESULTS
  Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases.
  
  
  CONCLUSIONS
  In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
authors.affiliation: Clínica e Centro de Pesquisa em Reprodução Humana Roger Abdelmassih, São Paulo, Brazil. dmitri@dozortsev.net
authors.forename: Dmitri
authors.initials: D
authors.lastname: Dozortsev
authors.forename: Rosa
authors.initials: R
authors.lastname: Neme
authors.forename: Michael P
authors.initials: MP
authors.lastname: Diamond
authors.forename: Soraya
authors.initials: S
authors.lastname: Abdelmassih
authors.forename: Vicente
authors.initials: V
authors.lastname: Abdelmassih
authors.forename: Flavio
authors.initials: F
authors.lastname: Oliveira
authors.forename: Roger
authors.initials: R
authors.lastname: Abdelmassih
mesh_terms: D001938:Brazil / Q000453:epidemiology; D004622:Embryo, Mammalian / Q000473:pathology*; D004822:Epididymis / Q000473:pathology*; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology / Q000628:therapy; D008297:Male; D009845:Oligospermia / Q000453:epidemiology / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods / Q000706:statistics & numerical data; D013094:Spermatozoa / Q000473:pathology* / Q000637:transplantation*; D013737:Testis / Q000473:pathology*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology