title: [A case of pulmonary Mycobacterium fortuitum infection successfully treated with Kampo treatments].
abstract: A 72-year-old male was referred to our hospital in August 2001 for his pulmonary M. fortuitum infection. His symptoms were coughing, pyrexia, hemoptysis, general malaise, and insomnia. He had been suffering from these symptoms since 1982, though the intensive anti-mycobacterial chemotherapy such as three-drug (RFP, SM, and INH), twice two-drug (KM and SM and cycloserine and enviomycin) and four-drug (CAM, EB, RFP, and KM) regimens were administered for 26 months from July 1999. His symptoms tentatively improved after chemotherapy, but soon recurred with smear positive sputum. We decided to withdraw all antibacterial agents to treat him with decoction of Ninjinyoueito according to the diagnostics Kampo medical science in September 2001. After this prescription, his subjective symptoms gradually improved, and ten months later his sputum converted to smear negative. Because of recurrence of his general malaise in August 2002, we replaced the Ninjinyoueito by Seishoekkito, based on the Kampo diagnostics. His physical conditions remained good until 2005. In addition, the sputum smear examination maintain the level below +/-. We evaluate that Kampo (Chinese traditional medicine) treatment resulted in favorable response. Though it is not common to prescribe Kampo-medicine for intractable infectious diseases, we believe that Kampo-medicine is effective in some cases associated with host defense mechanisms.
authors.affiliation: Department of Japanese Oriental (Kampo) Medicine, Aso-Iizuka Hospital. t-nogami@qd5.so-net.ne.jp
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nogami
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Sekiya
authors.forename: Tadamichi
authors.initials: T
authors.lastname: Mitsuma
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D019907:Mycobacterium fortuitum; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal; C072867:ren-shen-yang-rong-tang