title: [Resistance of infectious agents involved in low respiratory tract infections in France].
abstract: This review concerning the major lower respiratory tract pathogens in France has for aim to describe the epidemiology of resistance to beta-lactams, macrolides, ketolides, and fluoroquinolones especially in Streptococcus pneumoniae and Haemophilus influenzae. It should also provide new insights on the mechanisms of acquired resistance and the level of resistance conferred, highlighting the related ecological impact. In the context of this XVth consensus conference, this review should contribute to the elaboration of guidelines for the treatment of lower respiratory tract infections in adults.
authors.affiliation: Laboratoire de microbiologie, centre national de référence des pneumocoques, APHP, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75908 Paris cedex 15, France. emmanuelle.varon@hop.egp.ap-hop-paris.fr
authors.forename: E
authors.initials: E
authors.lastname: Varon
authors.forename: S
authors.initials: S
authors.lastname: Houssaye
mesh_terms: D000900:Anti-Bacterial Agents / Q000145:classification / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005602:France; D006192:Haemophilus Infections / Q000188:drug therapy; D006801:Humans; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents