Effects of dietary calcium intervention on adolescent mothers and newborns: A randomized controlled trial.
OBJECTIVE
To evaluate the effects of dietary calcium (Ca) intervention on adolescent pregnant mothers and their newborns.


METHODS
Seventy-two pregnant adolescent mothers were randomized into one of 3 groups: control, orange juice fortified with calcium, and dairy. The orange juice and dairy groups were required to take more than 1,200 mg Ca. Calcium tablets were added for those not able to meet required Ca. Maternal and infant weight, length, and blood pressure (BP) were recorded. Maternal dietary records were evaluated. Mother's blood was drawn for serum Ca, phosphate (P), magnesium (Mg), and vitamin 25-hydroxyvitamin D (D). Cord blood was collected for serum Ca and D. Newborn total body Ca was determined.


RESULTS
All mothers were similar in weight, height, and BP. Mothers in the orange juice plus calcium and dairy groups had higher intakes of Ca (1,472 mg and 1,771 mg) than controls (862 mg). One half of the mothers in the orange juice plus calcium group required Ca tablets. Mothers in the dairy group had higher intakes of P, D, and Mg, higher serum folate and D, and higher cord D levels. Mothers in the orange juice plus calcium group had higher serum P but lower serum folate and D. Infants (3,517+/-273 g) in the dairy group were heavier than infants in the control (3,277+/-177 g) and orange juice plus calcium (3,292+/-165 g) groups. Infants in the dairy group had higher total body calcium than control infants.


CONCLUSIONS
Calcium diet supplemented with dairy products during adolescent pregnancy resulted in higher maternal vitamin D and folate serum levels and higher newborn weight and bone mineralization compared with controls.
Chan
Gary M
GM
Division of Neonatology, Teen Mother and Child Program, University of Utah, Salt Lake City, Utah, USA. gchan@hsc.utah.edu
McElligott
Kathleen
K
McNaught
Teresa
T
Gill
Gurmail
G
D000293:Adolescent; D017195:Adolescent Nutritional Physiological Phenomena; D001628:Beverages; D001724:Birth Weight / Q000187:drug effects*; D002118:Calcium / Q000097:blood*; D002136:Calcium, Dietary / Q000008:administration & dosage* / Q000494:pharmacology; D032084:Citrus sinensis; D003611:Dairy Products; D019587:Dietary Supplements; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005527:Food, Fortified; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D008274:Magnesium / Q000097:blood; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D010710:Phosphates / Q000097:blood; D011247:Pregnancy / Q000097:blood*; D039401:Prenatal Nutritional Physiological Phenomena; D014807:Vitamin D / Q000031:analogs & derivatives / Q000097:blood
D002136:Calcium, Dietary; D010710:Phosphates; D014807:Vitamin D; C104450:25-hydroxyvitamin D; D008274:Magnesium; D002118:Calcium