title: [A 32-year-old patient with diarrhoea and acute kidney failure].
abstract: A 32-year-old male patient presented in the emergency department of our hospital with acute vomiting and diarrhoea. He reported occasional non-severe diarrhoea over several years in the past. Furthermore, at the time of presentation the patient had had anuria for several days. A prerenal and postrenal origin of the renal failure was excluded. A renal biopsy was performed and histopathological examination displayed findings consistent with a haemolytic-uraemic syndrome but no signs of glomerulonephritis. MRI examination of the small bowel revealed inflammatory alterations typical for Crohn's disease, even without histological verification. We describe haemolytic-waemic syndrome as manifestation of Crohn's disease for the first time.
authors.affiliation: Medizinische Klinik und Poliklinik II, Universitätsklinikum Leipzig, Ph.-Rosenthal-Strasse 27, 04103, Leipzig, Germany. albrecht.hoffmeister@medizin.uni-leipzig.de
authors.forename: A
authors.initials: A
authors.lastname: Hoffmeister
authors.forename: H
authors.initials: H
authors.lastname: Wittenburg
authors.forename: N
authors.initials: N
authors.lastname: Teich
authors.forename: A
authors.initials: A
authors.lastname: Bachmann
authors.forename: G
authors.initials: G
authors.lastname: Borte
authors.forename: J
authors.initials: J
authors.lastname: Mössner
authors.forename: H
authors.initials: H
authors.lastname: Achenbach
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D001706:Biopsy; D003424:Crohn Disease / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology*; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis*; D006801:Humans; D007421:Intestine, Small / Q000473:pathology; D007668:Kidney / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D014839:Vomiting / Q000209:etiology