title: Recovery of cognitive function in neuropsychiatric Langerhan's cell histiocytosis.
abstract: Langerhan's cell histiocytosis (LCH) has been described as a progressive neurological disorder marked by neurological and cognitive decline. The authors here report a case of a childhood LCH sufferer who made a significant recovery of neuropsychological function in the absence of motor recovery in late adolescence. This differential recovery of motor and cognitive functioning may relate to the interaction between LCH and childhood and adolescent neurodevelopmental processes.
authors.affiliation: Neuropsychiatry Unit, Melbourne Neuropsychiatry Center, Royal Melbourne Hospital, Melbourne, Australia.
authors.forename: Philip
authors.initials: P
authors.lastname: Ryan
authors.forename: Mark
authors.initials: M
authors.lastname: Walterfang
authors.forename: Amelia
authors.initials: A
authors.lastname: Scholes
authors.forename: John
authors.initials: J
authors.lastname: O'Donovan
authors.forename: Bruce
authors.initials: B
authors.lastname: Tomlinson
authors.forename: Dennis
authors.initials: D
authors.lastname: Velakoulis
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D003071:Cognition / Q000502:physiology*; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology / Q000523:psychology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology; D014888:Wechsler Scales