title: Presumed eccrine carcinoma metastatic to the choroid.
abstract: The purpose of this article is to describe a patient with presumed choroidal metastasis from an eccrine adenocarcinoma of the scalp. A 45-year-old Caucasian woman presented with decreased visual acuity. Ophthalmologic examination was unremarkable. Her past medical history was significant for eccrine carcinoma of the scalp. The patient developed bilateral cervical lymph node metastases, and received chemotherapy and radiotherapy. She had recurrence of the scalp lesion and developed bone metastasis. The patient was again referred to an ophthalmologist owing to reduced visual acuity. Multiple choroidal metastases were detected in right eye, and one metastatic lesion in left eye. The patient passed away 2 months after choroidal metastases. This is the first report of choroidal metastases from an eccrine carcinoma. This is a rare aggressive neoplasm with poor outcome in most cases of metastatic disease, and in this case report, uveal metastasis was indicative of poor prognosis.
authors.affiliation: Department of Ophthalmology, Instituto Brasileiro de Oftalmologia, Rio de Janeiro, Brazil.
authors.forename: Letícia R
authors.initials: LR
authors.lastname: Moura
authors.forename: Bernadete
authors.initials: B
authors.lastname: Ayres
authors.forename: Luciana
authors.initials: L
authors.lastname: Feijóo
authors.forename: Sérgio
authors.initials: S
authors.lastname: Romano
authors.forename: Alexandre N
authors.initials: AN
authors.lastname: Odashiro
authors.forename: Miguel N
authors.initials: MN
authors.lastname: Burnier
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D002830:Choroid Neoplasms / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009333:Neck; D012535:Scalp; D012878:Skin Neoplasms / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*