title: [Sepsis following transrectal prostate biopsy: a report of 2 cases and reviewed similar cases in Japan].
abstract: We report two cases of sepsis and disseminated intravascular coagulation (DIC), potentially fatal complications, following transrectal prostate biopsy. We also review similar cases reported in Japan. Case 1: A 63-year-old man received a cathartic and levofloxacin (LVFX) for prophylaxis. After transrectal prostate biopsy, he presented with fever and chills. Blood cultures grew Escherichia coli resistant to LVFX. Under a diagnosis of sepsis, he received intensive management that included endotoxin removal therapy. The patient was hospitalized for 27 days. Case 2: A 64-year-old man received a cathartic and cefazolin (CEZ) for prophylaxis. He presented with fever and chills after biopsy, and was admitted to hospital. Blood cultures grew E. coli resistant to CEZ. Under a diagnosis of sepsis, he received intravenous antibiotics, transfusion, and anti-DIC drugs. The patient was hospitalized for 11 days.
authors.affiliation: The Department of Urology, Division of Surgery, Tokai University School of Medicine.
authors.forename: Akio
authors.initials: A
authors.lastname: Hoshi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nitta
authors.forename: Sachiko
authors.initials: S
authors.lastname: Hongoh
authors.forename: Kazuya
authors.initials: K
authors.lastname: Hanai
authors.forename: Zenkai
authors.initials: Z
authors.lastname: Nishikawa
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Masanori
authors.initials: M
authors.lastname: Shima
authors.forename: Tadashi
authors.initials: T
authors.lastname: Hanai
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Hyochi
authors.forename: Yukio
authors.initials: Y
authors.lastname: Usui
authors.forename: Hideshi
authors.initials: H
authors.lastname: Miyakita
authors.forename: Toshiro
authors.initials: T
authors.lastname: Terachi
mesh_terms: D001706:Biopsy / Q000009:adverse effects*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004927:Escherichia coli Infections / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D012007:Rectum; D018805:Sepsis / Q000209:etiology*