Quantum dot encapsulation in viral capsids.
Incorporation of CdSe/ZnS semiconductor quantum dots (QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly(ethylene glycol) (PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation.
Dixit
Suraj K
SK
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.
Goicochea
Nancy L
NL
Daniel
Marie-Christine
MC
Murali
Ayaluru
A
Bronstein
Lyudmila
L
De
Mrinmoy
M
Stein
Barry
B
Rotello
Vincent M
VM
Kao
C Cheng
CC
Dragnea
Bogdan
B
D002213:Capsid / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D015336:Molecular Probe Techniques; D036103:Nanotechnology / Q000379:methods*; D045663:Quantum Dots; D019065:Virus Assembly
D020099:Coated Materials, Biocompatible