title: Centrosome duplication: is asymmetry the clue?
abstract: The structure of the yeast Sfi1-centrin complex, and its asymmetric position within the yeast centrosome, suggest a model for the initiation of centrosome duplication and provides a target for licensing this event.
authors.affiliation: MCD Biology, University of Colorado - Boulder, 347 UCB, Boulder, Colorado 80309-0347, USA.
authors.forename: Michele H
authors.initials: MH
authors.lastname: Jones
authors.forename: Mark
authors.initials: M
authors.lastname: Winey
mesh_terms: D018797:Cell Cycle Proteins / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D002455:Cell Division / Q000502:physiology*; D018385:Centrosome / Q000502:physiology*; D008954:Models, Biological; D020449:Repetitive Sequences, Amino Acid; D012097:Repressor Proteins / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D008941:Spindle Apparatus / Q000502:physiology*
chemical_list: D018797:Cell Cycle Proteins; D012097:Repressor Proteins; C121820:SFI1 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins