title: Selective substituent transfer from mixed zinc reagents in Ni-catalyzed anhydride alkylation.
abstract: The use of mixed zinc reagents in Ni-catalyzed anhydride alkylation results in preferential transfer of substituents (Ph > Me > Et >> iPr approximately TMSCH2) for the ligands bipy, dppe, and iPrPHOX. Utilization of such mixed species allows the use of 0.55 equiv of the diorganozinc reagent, effectively transferring both desired substituents when used in conjunction with a suitable second zinc reagent.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Johnson
authors.forename: Robert T
authors.initials: RT
authors.lastname: Yu
authors.forename: Paul
authors.initials: P
authors.lastname: Fink
authors.forename: Eric A
authors.initials: EA
authors.lastname: Bercot
authors.forename: Tomislav
authors.initials: T
authors.lastname: Rovis
mesh_terms: D000478:Alkylation; D000812:Anhydrides / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D000812:Anhydrides; D007202:Indicators and Reagents; D009532:Nickel; D015032:Zinc