[Effect of TCM formula for promoting blood circulation to remove blood stasis on brainstem auditory evoked potential and Transcranial Doppler parameters in patients with sudden deafness].
OBJECTIVE
To observe the therapeutic effect of Xuefu Zhuyu Decoction (XZD) on patients with sudden deafness (SD).


METHODS
Sixty patients with SD were treated with XZD, and the changes of brainstem auditory evoked potential (BAEP) and transcranial Doppler (TCD) parameters in them were detected before and after treatment and analyzed statistically.


RESULTS
I, III and V waveform and peak latency (PL) of BAEP, velocity of vertebral basilar arterial blood flow and parameters of cerebral blood flow in SD patients were all improved to different levels after treatment with XZD.


CONCLUSIONS
TCM formula for promoting blood circulation to remove blood stasis can improve BAEP and TCD parameters in SD patients; BAEP detection and TCD parameters can reflect nerve function and blood-supply state of internal ear and brain stem, and therefore are of great importance in guiding the clinical treatment and assessing the prognosis.
Zhu
Tian-min
TM
Rong-jiang Chengdu University of Traditional Chinese Medicine, Chengdu 610075. tmzhu@hotmail.com
Sun
Hong
H
Jin
Rong-jiang
RJ
D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects*; D005260:Female; D003639:Hearing Loss, Sudden / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008517:Phytotherapy; D017585:Ultrasonography, Doppler, Transcranial / Q000187:drug effects
D004365:Drugs, Chinese Herbal; C513826:Xue-Fu-Zhu-Yu decoction