title: [Necrotic myocarditis in acute eosinophilic lymphoblastic leukaemia].
abstract: BACKGROUND
  Hypereosinophilia can cause severe cardiac complications. The association between an acute lymphoblastic leukemia and hypereosinophilia was rare. We report a case of a 29-year-old man who presented a heart failure secondary to necrotic myocarditis related to an acute eosinophilic lymphoblastic leukaemia.
  
  
  METHODS
  The patient developed a heart failure and secondary a cardio-embolic stroke, due to a large mobile left ventricle thrombosis. His peripheral blood showed a total white count of 28,500 leucocytes/mm3 with 18,800 eosinophils/mm3. The myelogram cytology showed precursor B-cell acute lymphoblastic leukaemia with hypereosinophilia.
  
  
  CONCLUSIONS
  The possibility of the rapid emergence of cardiac lesions in hypereosinophilic syndromes warrants very close physician vigilance. An Echocardiography and MRI performed at the early stage and in the follow-up allow to detect and to manage these cardiac disorders.
authors.affiliation: Service de médecine interne, APHM, CHU Nord, chemin des Bourrely, 13326 Marseille cedex 20, France. karim.aissi@ap-hm.fr
authors.forename: K
authors.initials: K
authors.lastname: Aissi
authors.forename: P
authors.initials: P
authors.lastname: Rossi
authors.forename: T-B-V
authors.initials: TB
authors.lastname: Le
authors.forename: B
authors.initials: B
authors.lastname: Granel
authors.forename: D
authors.initials: D
authors.lastname: Bagnères
authors.forename: A-L
authors.initials: AL
authors.lastname: Demoux
authors.forename: S
authors.initials: S
authors.lastname: Bonin-Guillaume
authors.forename: R
authors.initials: R
authors.lastname: Costello
authors.forename: G
authors.initials: G
authors.lastname: Sebahoun
authors.forename: Y
authors.initials: Y
authors.lastname: Francès
mesh_terms: D000208:Acute Disease; D000328:Adult; D017809:Fatal Outcome; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D009205:Myocarditis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D009336:Necrosis; D020521:Stroke / Q000209:etiology