[Epidermal growth factor receptor inhibitors side effects].
Epidermal growth factor receptor (EGFR) inhibitors are a new group of drugs used in the treatment of several malignancies. Three molecules are approved at the moment: gefitinib and erlotinib for the treatment of non-small-cell lung cancer, and cetuximab for colorectal cancer. These drugs originate cutaneous side effects with a high frequency: acneiform rashes, paronychia and generalized xerodermia. In this paper we review these common side effects and how to manage them.
Guhl
Guillermo
G
Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, España. guhl@aedv.es
González-de Arriba
Ana
A
Daudén
Esteban
E
D017486:Acneiform Eruptions / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D066246:ErbB Receptors / Q000037:antagonists & inhibitors*; D006801:Humans
D066246:ErbB Receptors