title: The relationship between the knee adduction moment and knee pain in middle-aged women without radiographic osteoarthritis.
abstract: OBJECTIVE
  . An abnormally high knee adduction moment increases the medial tibiofemoral compartment load at the knee during gait, and is an important biomechanical marker of joint pathology. This cross-sectional study examines the relationship between the knee adduction moment and knee pain in middle-aged women without radiographic knee osteoarthritis (OA).
  
  
  METHODS
  Three-dimensional Vicon gait analyses were performed on 20 women who had knee pain but no radiological evidence of joint pathology.
  
  
  RESULTS
  In multivariate analysis, the peak knee adduction moment during the late stance phase of gait was inversely associated with knee pain [beta: -10.1 (95% CI -17.6, -2.7), p = 0.01] after adjustment for body mass index (BMI) and age. This explained that the knee adduction moment during late stance contributed 32% of the variance in knee pain. The peak knee adduction moment during early stance was not significantly associated with knee pain prior to and after adjustment for BMI and age.
  
  
  CONCLUSIONS
  There is a significant inverse association between the peak knee adduction moment during late stance and the amount of knee pain experienced by women without radiographic evidence of joint pathology. This may represent a compensatory mechanism to reduce medial tibiofemoral joint load in the setting of knee pain.
authors.affiliation: Department of Epidemiology and Preventive Medicine, Alfred Hospital, Monash University, Melbourne, Victoria, Australia.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Teichtahl
authors.forename: Anita E
authors.initials: AE
authors.lastname: Wluka
authors.forename: Meg E
authors.initials: ME
authors.lastname: Morris
authors.forename: Susan R
authors.initials: SR
authors.lastname: Davis
authors.forename: Flavia M
authors.initials: FM
authors.lastname: Cicuttini
mesh_terms: D018771:Arthralgia / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology*; D008875:Middle Aged; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000503:physiopathology*; D020370:Osteoarthritis, Knee / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011859:Radiography; D016059:Range of Motion, Articular; D013223:Statistics as Topic; D019415:Torque