title: Transient encephalopathy with reversible white matter lesions in children.
abstract: We report on two children with acute encephalopathy showing mild clinical manifestations and reversible white matter lesions. In both patients, MRI revealed high intensities on T (2)-weighted imaging and marked reductions of water diffusion in the white matter of the bilateral centrum semiovale and the corpus callosum. These abnormalities disappeared along with the neurological symptoms within a week in both patients. These children represent a characteristic group of patients among childhood acute encephalopathy.
authors.affiliation: Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan. okumura@med.nagoya-u.ac.jp
authors.forename: A
authors.initials: A
authors.lastname: Okumura
authors.forename: E
authors.initials: E
authors.lastname: Noda
authors.forename: T
authors.initials: T
authors.lastname: Ikuta
authors.forename: J
authors.initials: J
authors.lastname: Natsume
authors.forename: T
authors.initials: T
authors.lastname: Nagai
authors.forename: Y
authors.initials: Y
authors.lastname: Gotoh
authors.forename: T
authors.initials: T
authors.lastname: Ando
authors.forename: H
authors.initials: H
authors.lastname: Fukatsu
mesh_terms: D000208:Acute Disease; D001284:Atrophy; D001927:Brain Diseases / Q000188:drug therapy / Q000473:pathology*; D002648:Child; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009417:Nerve Tissue / Q000473:pathology
chemical_list: D016756:Immunoglobulins, Intravenous