title: Mitogenic effect of Carthamus lanatus extracts, fractions and constituents.
abstract: Extracts, fractions and constituents of Carthamus lanatus were tested for their mitogenic effect on bone marrow cells in mice. Most of the studied samples inhibited cell proliferation and only the flavonoid glycoside rutin caused increasing of mitotic activity.
authors.affiliation: Institute of Zoology, Bulgarian Academy of Sciences, 1000 Sofia, Bulgaria. topashka.mn@lycos.com
authors.forename: Margarita N
authors.initials: MN
authors.lastname: Topashka-Ancheva
authors.forename: Rilka M
authors.initials: RM
authors.lastname: Taskova
authors.forename: Nedjalka V
authors.initials: NV
authors.lastname: Handjieva
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000187:drug effects; D031178:Carthamus; D002453:Cell Cycle / Q000187:drug effects*; D005260:Female; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008934:Mitogens / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D008934:Mitogens; D010936:Plant Extracts