Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia.
OBJECTIVE
To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia.


METHODS
Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia.


METHODS
Private Infertility clinic.


METHODS
None, charts review.


METHODS
None, charts review.


METHODS
Clinical pregnancy rate (PR), implantation rate.


RESULTS
Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases.


CONCLUSIONS
In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
Dozortsev
Dmitri
D
Clínica e Centro de Pesquisa em Reprodução Humana Roger Abdelmassih, São Paulo, Brazil. dmitri@dozortsev.net
Neme
Rosa
R
Diamond
Michael P
MP
Abdelmassih
Soraya
S
Abdelmassih
Vicente
V
Oliveira
Flavio
F
Abdelmassih
Roger
R
D001938:Brazil / Q000453:epidemiology; D004622:Embryo, Mammalian / Q000473:pathology*; D004822:Epididymis / Q000473:pathology*; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology / Q000628:therapy; D008297:Male; D009845:Oligospermia / Q000453:epidemiology / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods / Q000706:statistics & numerical data; D013094:Spermatozoa / Q000473:pathology* / Q000637:transplantation*; D013737:Testis / Q000473:pathology*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology