title: Occluded infrainguinal bypass graft: potential source of limb-threatening emboli.
abstract: Surgical bypass represents one of the chief treatment modalities for peripheral arterial occlusive disease. Despite improving techniques, graft occlusion accounts for the majority of these bypass failures. Once occluded, however, these grafts are thought to rarely pose a threat for future ischemic events. This report describes two patients with previously thrombosed grafts who subsequently presented with limb-threatening ischemia owing to peripheral embolization from the graft. Two patients with occluded grafts presented with ipsilateral limb-threatening acute ischemia. Both of these patients developed severe acute limb-threatening ischemia weeks to months after known graft thrombosis. Arteriography revealed peripheral embolization in each case. Both patients were operated on for disconnection of the thrombosed graft from the native circulation and have been free of recurrent symptoms. The occluded graft, although generally innocuous, can be a source of peripheral emboli, resulting in peripheral embolization and acute limb ischemia. Both patients in this report developed limb-threatening ischemia owing to embolization from the cul-de-sac of occluded prosthetic grafts. Due to the rarity of the condition and its associated morbidity and mortality, awareness and recognition of this phenomenon are critical. Operative disconnection is recommended if the embolism occurs downstream of the graft and no other embolic source can be identified.
authors.affiliation: Section of Vascular and Endovascular Surgery, Department of Surgery, University of California, San Diego University of California, San Diego Medical Center, San Diego, CA, USA.
authors.forename: Ankur
authors.initials: A
authors.lastname: Chandra
authors.forename: Niren
authors.initials: N
authors.lastname: Angle
mesh_terms: D000208:Acute Disease; D000368:Aged; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004617:Embolism / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006083:Graft Occlusion, Vascular / Q000150:complications*; D006801:Humans; D007511:Ischemia / Q000601:surgery; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011859:Radiography