Translocation t(9;14)(p13;q32) in cases of splenic marginal zone lymphoma.
Translocation t(9;14)(p13;q32) involving PAX5 and IGH genes was first described in lymphoplasmacytic lymphoma. New data suggest that this translocation is not restricted to a specific morphologic subtype but occurs in other B-cell lymphomas. We present three cases with a diagnosis of splenic marginal zone lymphoma and t(9;14) confirmed by fluorescent in situ hybridization.
Baró
Cristina
C
Salido
Marta
M
Domingo
Alicia
A
Granada
Isabel
I
Colomo
Lluís
L
Serrano
Sergi
S
Solé
Francesc
F
D000368:Aged; D002883:Chromosomes, Human, Pair 14; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D018442:Lymphoma, B-Cell, Marginal Zone / Q000235:genetics*; D013160:Splenic Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic