title: The glomerular filter: Biologic and genetic complexity.
abstract: The list of known genes that, when altered, cause proteinuric renal disease continues to increase. Recent mouse and human genetic studies, including that by Hasselbacher et al., are refocusing our attention on glomerular basement membrane components as critical to the barrier to protein filtration.
authors.affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: S V
authors.initials: SV
authors.lastname: Dandapani
authors.forename: M R
authors.initials: MR
authors.lastname: Pollak
mesh_terms: D002675:Child, Preschool; D005808:Genes, Recessive; D050533:Glomerular Basement Membrane / Q000737:chemistry; D006720:Homozygote; D006801:Humans; D007678:Kidney Glomerulus / Q000502:physiology*; D007797:Laminin / Q000737:chemistry / Q000235:genetics*; D020125:Mutation, Missense; D009404:Nephrotic Syndrome / Q000235:genetics* / Q000473:pathology*; D020161:Physical Chromosome Mapping
chemical_list: D007797:Laminin; C058783:laminin beta2