Increasing cortical activity in auditory areas through neurofeedback functional magnetic resonance imaging.
We report a functional magnetic resonance imaging method to deliver task-specific brain activities as biofeedback signals to guide individuals to increase cortical activity in auditory areas during sound stimulation. A total of 11 study participants underwent multiple functional magnetic resonance imaging scan sessions, while the changes in the activated cortical volume within the primary and secondary auditory areas were fed back to them between scan sessions. On the basis of the feedback information, participants attempted to increase the number of significant voxels during the subsequent trial sessions by adjusting their level of attention to the auditory stimuli. Results showed that the group of individuals who received the feedback were able to increase the activation volume and blood oxygenation level-dependent signal to a greater degree than the control group.
Yoo
Seung-Schik
SS
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. yoo@bwh.harvard.edu
O'Leary
Heather M
HM
Fairneny
Ty
T
Chen
Nan-Kuei
NK
Panych
Lawrence P
LP
Park
HyunWook
H
Jolesz
Ferenc A
FA
D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D001303:Auditory Cortex / Q000098:blood supply* / Q000502:physiology*; D001931:Brain Mapping; D005246:Feedback / Q000502:physiology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood
D010100:Oxygen