Review article: should we treat symptoms or lesions in Crohn's disease? The case for treating symptoms.
Apart from treating symptoms, mucosal healing is a reasonable aim of therapy in Crohn's disease. In most patients, however, the disease takes a mild course and treating symptoms seems sufficient. Eliminating lesions may change the course of the disease long-term but this has not yet been proven. Thus far we need to treat symptoms efficiently and may attempt to restore bacterial epithelial interaction.
Schölmerich
J
J
Klinik und Poliklinik für Innere Medizin I, Klinikum der Universität Regensburg, Regensburg, Germany. juergen.schoelmerich@klinik.uni-r.de
D003424:Crohn Disease / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007413:Intestinal Mucosa / Q000187:drug effects*; D012907:Smoking / Q000009:adverse effects
D007166:Immunosuppressive Agents