title: Effects of formalin feeding or administering into the crops of white leghorn cockerels on hematological and biochemical parameters.
abstract: Formalin administered (15 and 20 mL) into the crops of White Leghorn cockerels resulted in behavioral alterations, included depression, dullness, staggering, somnolence, anorexia, and decreased frequency of crowing. A significant decrease was observed in red blood cell counts, hemoglobin concentration, packed cell volume, and leukocyte counts in birds fed higher levels of formalin. Decreasing and increasing trends in concentrations of serum proteins and enzymes, respectively, were observed with increases in formalin doses. Significantly lower blood glucose and testosterone levels and significantly (P < 0.05) higher blood urea and creatinine concentrations were observed in birds fed higher formalin levels. No gross or microscopic lesions were observed in the birds fed different levels of formalin mixed in feed. These changes suggested that the formalin mixed in feed might have evaporated, and, hence, the amount ingested might have been too low to induce pathological changes. It was concluded from the present study that formalin mixed up to 5 mL/kg of feed, corresponding to 10 mL/bird of 3% formalin in drinking water by crop tube had no adverse effects on the health of White Leghorn cockerels.
authors.affiliation: Department of Veterinary Pathology, University of Agriculture, Faisalabad-38040, Pakistan. ahrar1122@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Khan
authors.forename: S M
authors.initials: SM
authors.lastname: Hussain
authors.forename: M Z
authors.initials: MZ
authors.lastname: Khan
mesh_terms: D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D002645:Chickens / Q000097:blood*; D003426:Crop, Avian / Q000187:drug effects*; D004202:Disinfectants / Q000008:administration & dosage* / Q000009:adverse effects* / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D005557:Formaldehyde / Q000008:administration & dosage* / Q000009:adverse effects* / Q000633:toxicity; D008297:Male
chemical_list: D004202:Disinfectants; D005557:Formaldehyde