title: Drug provocation test in patient with antituberculosis drug allergy.
abstract: Hypersensitivity reaction is an unexpected drug adverse effect which sometimes can lead to fatal condition. Confirmation of the suspected drugs that cause hypersensitivity reaction is sometimes difficult. Drug provocation test is still a gold standard to establish the diagnosis of hypersensitivity to certain drugs or agents. Drug provocation test is a controlled drug treatment which aims at making diagnosis of hypersensitivity reaction to drugs. We reported a demonstration case of a 47 year-old female patient with hypersensitivity to anti tuberculosis drugs (isoniazid, rifampicin, pyrazinamid and ethambutol). Drug provocation test is important in this case to confirm which drug had caused hypersensitivity reaction because anti tuberculosis drugs were the treatment of choice for her illness.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta.
authors.forename: Didi
authors.initials: D
authors.lastname: Kurniadhi
authors.forename: Andhika
authors.initials: A
authors.lastname: Rahman
authors.forename: Linda K
authors.initials: LK
authors.lastname: Wijaya
authors.forename: Nanang
authors.initials: N
authors.lastname: Sukmana
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D008875:Middle Aged; D014388:Tuberculosis, Lymph Node / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents