title: Deletion (21)(q21.2q22.12) as a sole clonal cytogenetic abnormality in a lobular capillary hemangioma of the nasal cavity.
abstract: A clonal deletion (21)(q21.2q22.12) was detected as a sole cytogenetic abnormality in a lobular capillary hemangioma (pyogenic granuloma) of the nasal cavity. This finding supports a neoplastic, rather than reactive, nature for this lesion. To our knowledge, these rare lesions have not previously been studied by cytogenetics.
authors.affiliation: Department of Pathology, Scott and White Memorial Hospital and Clinic and Scott, Sherwood and Brindley Foundation, The Texas A&M University System Health Science Center College of Medicine, Temple, 76508, USA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Truss
authors.forename: Sheila M
authors.initials: SM
authors.lastname: Dobin
authors.forename: Ludvik R
authors.initials: LR
authors.lastname: Donner
mesh_terms: D000328:Adult; D002872:Chromosome Deletion; D002891:Chromosomes, Human, Pair 21; D006258:Head and Neck Neoplasms / Q000235:genetics* / Q000473:pathology; D006391:Hemangioma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D009296:Nasal Cavity / Q000473:pathology*