Cell signalling: changing shape changes the signal.
Recent experiments have revealed the existence of subcellular gradients of signalling molecules. A new modelling study shows that changes in cell shape or size allow gradient-controlled pathways to be turned on or off simply by altering the distance between the signal source and targets.
Howard
Martin
M
Department of Mathematics, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. mjhowa@imperial.ac.uk
D048430:Cell Shape / Q000502:physiology*; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology*