title: Life threatening exacerbation in idiopathic pulmonary hemosiderosis salvaged by cyclophosphamide infusion.
abstract: A seven-year-old girl presented with frequent fever, cough and shortness of breath of three months duration. On the basis of her clinical features, peripheral blood and sputum findings, she was diagnosed as a case of idiopathic pulmonary hemosiderosis. After initial stabilisation with steroids and chloroquine, she presented four years later with massive pulmonary hemorrhage and respiratory failure, which responded dramatically to cyclophosphamide infusion. The rare occurrence of pulmonary hemosiderosis and different treatment regimens is discussed.
authors.affiliation: Pulmonary and Critical Care Division, Kalawati Saran Children's Hospital and Lady Hardinge Medical College, New Delhi, India. dr_rahul6@hotmail.com
authors.forename: Rahul
authors.initials: R
authors.lastname: Naithani
authors.forename: Jagdish
authors.initials: J
authors.lastname: Chandra
authors.forename: Varinder
authors.initials: V
authors.lastname: Singh
authors.forename: Veerendra
authors.initials: V
authors.lastname: Kumar
authors.forename: N K
authors.initials: NK
authors.lastname: Dubey
mesh_terms: D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage*; D005260:Female; D006486:Hemosiderosis / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008171:Lung Diseases / Q000188:drug therapy*
chemical_list: D003520:Cyclophosphamide