Depression and suicidal ideation after predictive testing for Huntington's disease: a two-year follow-up study.
The present study reports a two-year follow-up of psychological effects of predictive testing for Huntington's disease. Questionnaires assessing depression, general health, well-being, self injurious behavior, life satisfaction, and lifestyle were completed by 35 carriers and 58 non-carriers before the predictive test, and 2, 6, 12, and 24 months afterwards. Both carriers and non-carriers showed high suicidal ideation before the predictive testing. Depression scores and frequency of suicidal thoughts increased for carriers, compared to non-carriers, over time. There were no differences regarding life satisfaction or life style between carriers and non-carriers. Predictive testing was beneficial in reducing overall ill-health symptoms and increasing well-being for those initially expressing concern about Huntington's disease. The importance of assessing suicidal ideation and of continuing to provide adequate support is emphasized.
Larsson
Maria U
MU
Neurotec Department, Karolinska Institutet, Stockholm, Sweden. Mia.Larsson@ki.se
Luszcz
Mary A
MA
Bui
The-Hung
TH
Wahlin
Tarja-Brita Robins
TB
D003863:Depression / Q000523:psychology*; D005500:Follow-Up Studies; D005820:Genetic Testing / Q000523:psychology*; D006801:Humans; D008019:Life Style; D017060:Patient Satisfaction; D013405:Suicide / Q000523:psychology*