title: Antimicrobial metabolites produced by an intertidal Acremonium furcatum.
abstract: In a screening for antimicrobial metabolites, amides of D-allo- and L-isoleucine derivatives were isolated from the culture of a marine strain of Acremonium furcatum. Structural elucidation of these compounds was performed by analysis of spectroscopic data and confirmed by synthesis. All of the compounds, natural and synthetic intermediates, were bioassayed against bacteria and phytopathogenic fungi, with many showing remarkable antifungal activities.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. II, 1428 Buenos Aires, Argentina.
authors.forename: Gabriela L
authors.initials: GL
authors.lastname: Gallardo
authors.forename: Matías
authors.initials: M
authors.lastname: Butler
authors.forename: Mariana L
authors.initials: ML
authors.lastname: Gallo
authors.forename: M Alejandra
authors.initials: MA
authors.lastname: Rodríguez
authors.forename: Marcos N
authors.initials: MN
authors.lastname: Eberlin
authors.forename: Gabriela M
authors.initials: GM
authors.lastname: Cabrera
mesh_terms: D000164:Acremonium / Q000737:chemistry* / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism; D001419:Bacteria / Q000187:drug effects; D015394:Molecular Structure
chemical_list: D000900:Anti-Bacterial Agents