New concepts in the diagnosis and management of optic nerve sheath meningioma.
Optic nerve sheath meningiomas are by far the most common tumors of the optic nerve sheath. The diagnosis can be suspected in most cases from clinical findings and supported by the results of neuroimaging, obviating tissue biopsy in the majority of cases. Observation may be appropriate in patients with mild or no visual deficit or in whom visual loss is not progressing, whereas stereotactic fractionated radiation therapy has been demonstrated to improve or stabilize vision in progressive or advanced cases. Attempts at surgical excision, and even biopsy, of optic nerve sheath meningiomas are associated with a high risk of blindness and should be reserved for the rare case of an anteriorly located, primarily exophytic tumor with focal involvement of the dural sheath.
Miller
Neil R
NR
Wilmer Eye Institute, the Johns Hopkins Hospital, Baltimore, Maryland, USA. nrmiller@jhmi.edu
D006801:Humans; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008579:Meningioma / Q000175:diagnosis* / Q000628:therapy*; D019574:Optic Nerve Neoplasms / Q000175:diagnosis* / Q000628:therapy*