title: Use of nonthermal blue (405- to 420-nm) and near-infrared light (850- to 900-nm) dual-wavelength system in combination with glycolic acid peels and topical vitamin C for skin photorejuvenation.
abstract: OBJECTIVE
  A major cause of skin aging is a chronic microinflammation created by environmental conditions and ultraviolet exposures. The hand-free application on the skin of a new intense light combining a narrowband blue-light (405- to 420-nm) antiinflammatory emission and a near-infrared (850- to 890-nm) emission inducing self-defense mechanisms provides a new component to photorejuvenation and antiaging treatment protocols.
  
  
  METHODS
  An innovative skin rejuvenation schedule is presented in this study. It includes skin exposure to the light, with concomitant glycolic peels and daily vitamin C cream regimen for group A and only topical vitamin C cream and glycolic peels for control group B.
  
  
  RESULTS
  Results show a significant improvement on pore size, rhytids, and radiance in group A. Conversely no improvement is noticed in group B except for a brief increase of skin radiance. Mechanisms of action of that specific light source are discussed.
  
  
  CONCLUSIONS
  The exposure to this device can clinically enhance conventional antiaging protocols in skin rejuvenation.
authors.affiliation: CLDP (Center Laser Dermatologie & Phlébologie), La Croisée, Clapiers, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Fournier
authors.forename: Klaus
authors.initials: K
authors.lastname: Fritz
authors.forename: Serge
authors.initials: S
authors.lastname: Mordon
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001205:Ascorbic Acid / Q000008:administration & dosage*; D005260:Female; D006016:Glycolates / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D017060:Patient Satisfaction; D010789:Phototherapy / Q000295:instrumentation*; D012060:Rejuvenation; D015595:Skin Aging; D011795:Surveys and Questionnaires; D013696:Temperature; D016896:Treatment Outcome; D014815:Vitamins / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D006016:Glycolates; D007641:Keratolytic Agents; D009824:Ointments; D014815:Vitamins; C031149:glycolic acid; D001205:Ascorbic Acid