title: [Influence of carbachol and atropine on the motor cortex neurons in cat operant reflex].
abstract: Effects of carbachol and atropine on the caused and background impulse neurons activity during operant reflex were studied on twenty motor cortex neurons. Motor cortex neurons in dependence of changes impulse neurons activity after carbachol administration have been divided into two groups; the first group includes neurons with a long influence on impulse activity and the second--with short. Carbachol applied by ionophoresis to motor cortex promoted authentic increase of background impulse activity and duration of the caused reaction in both groups. Abministration of atropine, an antagonist of m-cholinergic receptors significantly reduced parameters of background impulse activity and duration of the caused reaction. It was suggested that acetylcholine released by terminals of the cholinergic fibers in natural conditions takes part in maintenance of motor cortex neuron background activity and provides sufficient intensity of the motor commands generated by these cells; the given effects mediated by m-cholinergic receptors.
authors.forename: O O
authors.initials: OO
authors.lastname: Shchihlo
mesh_terms: D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D002217:Carbachol / Q000494:pharmacology*; D002415:Cats; D003216:Conditioning, Operant / Q000187:drug effects*; D005071:Evoked Potentials / Q000187:drug effects; D009044:Motor Cortex / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D018727:Muscarinic Antagonists / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D011976:Receptors, Muscarinic / Q000378:metabolism
chemical_list: D018727:Muscarinic Antagonists; D011976:Receptors, Muscarinic; D001285:Atropine; D002217:Carbachol