title: Rapid regulatory effect of tri-iodothyronine (T3) on antioxidant enzyme activities in a fish Anabas testudineus (Bloch): short-term in vivo and in vitro study.
abstract: The short-term action of thyroid hormone tri-iodothyronine (T3) was studied in vivo and in vitro on antioxidant enzyme activities in a teleost Anabas testudineus (Bloch). T3 injection in vivo (200 ng) in normal fish decreased the lipid peroxidation products and increased superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx) activities after 30 min. T3 in vitro (10(-6) M) increased the antioxidant activities of catalase, glutathione reductase (GR), GPx and glutathione level after 15/30 min, except SOD, substantiating in vivo effects in normal fish. The results suggest a rapid regulatory effect of thyroid hormone in vivo and in vitro, in the removal of reactive oxygen species in A testudineus.
authors.affiliation: Department of Zoology, University of Kerala, Kariavattom, Thiruvananthapuram-695 581, Kerala, India.
authors.forename: P
authors.initials: P
authors.lastname: Sreejith
authors.forename: O V
authors.initials: OV
authors.lastname: Oommen
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism*; D004789:Enzyme Activation / Q000502:physiology; D005979:Glutathione Peroxidase / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism*; D010471:Perches / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*; D014284:Triiodothyronine / Q000502:physiology*
chemical_list: D000975:Antioxidants; D014284:Triiodothyronine; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase