From pore to kinetochore and back: regulating envelope assembly.
Reassembly of the nuclear envelope following mitosis is a fundamental process that remains only partially understood. Two recent reports by and in the September 5 issue of Current Biology identify a novel protein, MEL-28, that shuttles between the nuclear pore complex and kinetochore and is essential for envelope assembly in C. elegans early embryos.
Roux
Kyle J
KJ
Department of Anatomy and Cell Biology, The University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, 32606, USA.
Burke
Brian
B
D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology* / Q000378:metabolism; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism / Q000502:physiology*; D018386:Kinetochores / Q000378:metabolism*; D008938:Mitosis; D009685:Nuclear Envelope / Q000378:metabolism*; D022022:Nuclear Pore / Q000378:metabolism; D008941:Spindle Apparatus
D029742:Caenorhabditis elegans Proteins