Frailty.
Frailty is a common condition in older people. It now can be objectively defined by the Fried criteria. When recognized, early intervention should begin with the institution of endurance, resistance, and balance exercises. In men with testosterone deficiency a trial of testosterone replacement should be considered. Vitamin D deficiency needs to be recognized and treated. Appropriate treatment of underlying diseases, such as anemia, diabetes mellitus, and congestive heart failure, are a key management principle. In people who have frailty aggressive health promotion and disease prevention techniques can lead to an inhibition of the downward spiral to disability.
Morley
John E
JE
Division of Geriatric Medicine, Saint Louis University School of Medicine, 1402 South Grand Boulevard, M238, MO 63104, USA. morley@slu.edu
Haren
Matthew T
MT
Rolland
Yves
Y
Kim
Moon Jong
MJ
D000368:Aged; D015984:Causality; D002908:Chronic Disease / Q000145:classification* / Q000453:epidemiology / Q000628:therapy; D020934:Ciliary Neurotrophic Factor / Q000378:metabolism; D015897:Comorbidity; D015444:Exercise / Q000502:physiology; D005260:Female; D016330:Frail Elderly / Q000706:statistics & numerical data; D006133:Growth Substances / Q000378:metabolism; D006801:Humans; D008297:Male; D009046:Motor Neurons / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology; D012307:Risk Factors; D013739:Testosterone / Q000172:deficiency; D014808:Vitamin D Deficiency / Q000503:physiopathology
D020934:Ciliary Neurotrophic Factor; D006133:Growth Substances; D013739:Testosterone