title: Aspergillus meningitis following spinal anaesthesia for caesarean section in Colombo, Sri Lanka.
abstract: We report six cases of Aspergillus meningitis after spinal anaesthesia for caesarean section administered in June and July 2005. Three patients died before a fungal infection was confirmed at the first post-mortem examination in August. Thereafter anti-fungal therapy was successful in saving the lives of the other three patients. Some syringes and spinal needles supplied to the hospitals concerned were found to be contaminated with Aspergillus fumigatus. Investigators found that medical supply storage facilities were substandard following the influx of donations after the tsunami of December 2004.
authors.affiliation: dayarod7@sltnet.lk
authors.forename: N
authors.initials: N
authors.lastname: Rodrigo
authors.forename: K N T
authors.initials: KN
authors.lastname: Perera
authors.forename: R
authors.initials: R
authors.lastname: Ranwala
authors.forename: S
authors.initials: S
authors.lastname: Jayasinghe
authors.forename: A
authors.initials: A
authors.lastname: Warnakulasuriya
authors.forename: S
authors.initials: S
authors.lastname: Hapuarachchi
mesh_terms: D020434:Abducens Nerve Diseases / Q000209:etiology; D000328:Adult; D000773:Anesthesia, Obstetrical / Q000009:adverse effects*; D000775:Anesthesia, Spinal / Q000009:adverse effects*; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000209:etiology* / Q000473:pathology; D001921:Brain / Q000382:microbiology / Q000473:pathology; D002585:Cesarean Section; D016640:Diabetes, Gestational / Q000503:physiopathology; D017809:Fatal Outcome; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D015600:Glasgow Coma Scale; D006801:Humans; D016921:Meningitis, Fungal / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D011743:Pyrimidines / Q000627:therapeutic use; D012121:Respiration, Artificial; D013188:Sri Lanka; D014057:Tomography, X-Ray Computed; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D015725:Fluconazole; D065819:Voriconazole