Preoperative evaluation of living related kidney donor: which kidney to donate?
OBJECTIVE
As the number of cadaveric donor is far beyond the demand of the waiting list, living related kidney transplantation is important for the worldwide organ shortage. Besides, living related transplantation has advantages compared with cadaveric transplantation in terms of graft function and survival. However, the remaining kidney function of the living donor needs to be evaluated.


METHODS
We collected 28 paired living kidney donations from March 2003 to March 2005. All patients underwent laparoscopic donor nephrectomy. The preoperative kidney evaluation included renal echography, renal nuclear scan, computed tomography angiography (CTA), and creatinine clearance (CCr). The renal function of the donor kidney was expressed as (donor kidney/both kidneys)%. The percentage renal function from renal echography, renal nuclear scan, and CTA were correlated with CCr.


RESULTS
The mean percentage of donor kidney function according to renal echo, nuclear scan, and CTA were 49.77%, 51.83%, and 50.70%, respectively. The correlation coefficients for renal echography, nuclear scan, and CTA to CCr were -0.316, -0.201, and 0.123, respectively. The correlation coefficients for renal echography, nuclear scan, and CTA to postoperative serum creatinine of donor were 0.426, 0.036, and -0.119, respectively.


CONCLUSIONS
From the viewpoint of donor postoperative residual renal function, preoperative renal sonography offered a better predictive value than nuclear scan or CTA.
Wu
C-T
CT
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu-Hsing Street, Kewishan Hsiang, Taoyuan 333, Taiwan.
Liu
K-L
KL
Chu
S-H
SH
Chiang
Y-J
YJ
D000328:Adult; D005190:Family; D005260:Female; D007839:Functional Laterality; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D007668:Kidney; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000502:physiology*; D010535:Laparoscopy; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011300:Preoperative Care; D012189:Retrospective Studies; D020858:Tissue and Organ Harvesting