title: Blood pressure changes during the initial week after different subtypes of ischemic stroke.
abstract: OBJECTIVE
  The purpose of this study was to clarify the differences in the acute blood pressure course among different ischemic stroke subtypes.
  
  
  METHODS
  We divided 588 consecutive patients with acute brain infarction into four clinical subgroups to study the blood pressure levels during the initial 6 hospital days.
  
  
  RESULTS
  During the 6 days, systolic blood pressure of lacunar and atherothrombotic patients was higher (P=0.0001) and diastolic blood pressure of lacunar patients was higher (P=0.0371) than of patients with the other subtypes. Preexisting hypertension was associated with elevated acute systolic blood pressure in all patients and in each subtype and with elevated acute diastolic blood pressure in all patients, cardioembolic patients, and patients with stroke of other etiology. After adjustment by preexisting hypertension, diabetes mellitus with a hemoglobin A1c >7.0% was associated with elevated systolic blood pressure in all, lacunar, and cardioembolic patients and with diastolic blood pressure in all patients.
  
  
  CONCLUSIONS
  Blood pressure course of patients sustaining acute stroke varied widely according to stroke subtypes. Poorly controlled diabetes mellitus, as well as preexisting hypertension, appeared to influence blood pressure during the initial week of stroke.
authors.affiliation: Department of Cerebrovascular Disease and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan. toyoda@hsp.ncvc.go.jp
authors.forename: Kazunori
authors.initials: K
authors.lastname: Toyoda
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Okada
authors.forename: Shigeru
authors.initials: S
authors.lastname: Fujimoto
authors.forename: Noriko
authors.initials: N
authors.lastname: Hagiwara
authors.forename: Koh
authors.initials: K
authors.lastname: Nakachi
authors.forename: Takanari
authors.initials: T
authors.lastname: Kitazono
authors.forename: Setsuro
authors.initials: S
authors.lastname: Ibayashi
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Iida
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D020520:Brain Infarction / Q000145:classification / Q000150:complications / Q000503:physiopathology*; D002545:Brain Ischemia / Q000145:classification / Q000150:complications / Q000503:physiopathology*; D048909:Diabetes Complications / Q000503:physiopathology; D003971:Diastole; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology; D002537:Intracranial Arteriosclerosis / Q000150:complications / Q000503:physiopathology; D020766:Intracranial Embolism / Q000150:complications / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000145:classification / Q000150:complications / Q000503:physiopathology*; D013997:Time Factors