title: Immunohistochemical analysis of an ectopic endometriosis in the uterine round ligament.
abstract: A rare case of the inguinal endometriosis was reported with immunohistochemical analysis. A 28-year-old woman had a thumb-sized tumor in the right groin for two years with a gradual increase in size and pain. An operation revealed an elastic hard tumor with an unclear margin and adhesion to the uterine round ligament. The histology showed irregular proliferation of the endometrial glands and stroma. The glandular epithelium stained weakly positive against CD125 antibody and the stromal matrix stained strongly positive against CD10 antibody. The nucleus in both the epithelial and stromal cells stained strongly positive against progesterone and estrogen receptor antibodies, and the cytoplasm in both types of cells stained moderately positive against COX-2 (cyclooxygenase-2) antibody. In conclusion, the combination of estrogen or progesterone receptor antibody for the nucleus and CD10 or COX-2 antibody for the cytoplasm could enhance the accuracy of diagnosis for ectopic endometriosis.
authors.affiliation: Division of Plastic Surgery, National Hospital Organization Disaster Medical Center, 3256 Midori-cho, Tachikawa-shi, Tokyo 190-0014, Japan. st911@10et.com
authors.forename: Shinichi
authors.initials: S
authors.lastname: Terada
authors.forename: Yachiyo
authors.initials: Y
authors.lastname: Miyata
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Higashimori
authors.forename: Takanari
authors.initials: T
authors.lastname: Arai
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Motohiro
authors.initials: M
authors.lastname: Nozaki