title: Treatment of pulmonary hypertension with sildenafil in a neonate with spondyloepiphyseal dysplasia congenita.
abstract: Persistent pulmonary hypertension of the newborn (PPHN) remains an important cause of mortality and morbidity in the term neonate. Preliminary but limited data suggest that there may be a role for sildenafil in the treatment of PPHN. We report the successful treatment of PPHN caused by pulmonary hypoplasia in a patient with spondyloepiphyseal dysplasia congenita.
authors.affiliation: Department of Neonatology, The Canberra Hospital, Garran, Australia. zsuzsoka.kecskes@act.gov.au
authors.forename: Zsuzsoka
authors.initials: Z
authors.lastname: Kecskes
authors.forename: Alison
authors.initials: A
authors.lastname: Kent
authors.forename: Graham
authors.initials: G
authors.lastname: Reynolds
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010009:Osteochondrodysplasias / Q000150:complications / Q000151:congenital; D010547:Persistent Fetal Circulation Syndrome / Q000188:drug therapy* / Q000209:etiology; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate