A simulation method for the firing sequences of motor units.
The firing sequences of motoneurons contain important information with regard to the underlying neural processes. Several methods have been proposed in the literature to simulate these sequences, however, one of the limitations is that they are not capable of simulating the complex neural dynamics of motor neurons, especially those of concurrently active ones, such as motor unit synchrony and motor unit common drive. In this paper, a novel model based on the Hodgkin-Huxley (HH) system is proposed, which has the ability to simulate the complex neurodynamics of the firing sequences of motor neurons. The model is presented at the cellular level and network level, and some simulation results from a simple 3-neuron network are presented to demonstrate its applications.
Jiang
Ning
N
Department of Electrical and Computer Engineering, Institute of Biomedical Engineering, University of New Brunswick, Fredericton, NB, Canada E3B 5A3. ning.jiang@unb.ca
Englehart
Kevin B
KB
Parker
Philip A
PA
D000200:Action Potentials / Q000502:physiology*; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D005246:Feedback / Q000502:physiology; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*