Diastereoselective synthesis of beta-Aryl-C-nucleosides from 1,2-anhydrosugars.
The cis opening of glycal epoxides with arylaluminum reagents provides strict stereocontrol in C-glycosylation. beta-Aryl-C-2-deoxynucleosides are obtained from known glycals by an epoxidation-glycosylation-deoxygenation sequence.
Singh
Ishwar
I
Humboldt-Universität zu Berlin, Institut für Chemie, Brook-Taylor-Strasse 2, D-12489 Berlin, Germany.
Seitz
Oliver
O
D002241:Carbohydrates / Q000737:chemistry*; D009705:Nucleosides / Q000138:chemical synthesis*; D013237:Stereoisomerism
D002241:Carbohydrates; D009705:Nucleosides