title: Fast 1H spectroscopic imaging using steady state free precession and spectral-spatial RF pulses.
abstract: Recently, new methods for fast (1)H spectroscopic imaging based on the condition of steady state free precession (SSFP) were introduced to achieve a high signal-to-noise ratio at short minimum measurement times. In this work, a major improvement is presented to overcome a crucial drawback in some of the former sequences: the lack of spatial selectivity. Good spectral selectivity at very high sampling efficiency can be achieved by using spectral-spatial RF pulses, and combined with localised shimming. Results are shown from both phantom experiments and in vivo studies on the rat brain acquired at 4.7 T.
authors.affiliation: Universitä Bremen, FB 2, Chemie, Leobener Street NW2/C, 28334, Bremen, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Geppert
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Dreher
authors.forename: Matthias
authors.initials: M
authors.lastname: Althaus
authors.forename: Dieter
authors.initials: D
authors.lastname: Leibfritz
mesh_terms: D000818:Animals; D016477:Artifacts; D001921:Brain / Q000473:pathology*; D003198:Computer Simulation; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D009682:Magnetic Resonance Spectroscopy; D019047:Phantoms, Imaging; D017785:Photons; D051381:Rats; D012815:Signal Processing, Computer-Assisted; D013053:Spectrophotometry / Q000295:instrumentation / Q000379:methods*; D013997:Time Factors