[Lymphoma with initial renal involvement: four cases].
OBJECTIVE
To present a comprehensive description of the clinical features of patients with renal manifestations during lymphoma.


METHODS
Retrospective review of medical records from all patients diagnosed with lymphoma associated with kidney involvement in our hospital between 1996 to 2004. Four cases were identified and analysed.


RESULTS
Four patients presented a non-Hodgkin's lymphoma. One patient showed intravascular large B-cell lymphoma, revealed by proteinuria. Another patient had a nephrotic syndrome, and two had a renal mass. Renal histology allowed diagnosis of lymphoma in 3 cases.


CONCLUSIONS
The diagnosis of lymphoma associated with renal involvement is rather difficult, and more specifically in case of intravascular large B-cell lymphoma, or even primary renal lymphoma. We present here a comprehensive review of the literature and we discuss pathogenesis of these conditions.
Dauchy
F-A
FA
Médecine interne et maladies tropicales, hôpital Saint-André, CHU de Bordeaux, université Bordeaux-II, 1, rue Jean-Burguet, 33075 Bordeaux cedex, France. fadauchy@hotmail.com
Etienne
G
G
Deminière
C
C
Combe
C
C
Merville
P
P
Longy-Boursier
M
M
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D009404:Nephrotic Syndrome / Q000209:etiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000628:therapy