An efficient synthesis and biological activity of substituted p-benzoquinones.
An efficient synthesis of 2,5-diarylamino-3,6-dichloro-1,4-benzoquinone derivatives has been achieved by condensing mono substituted anilines with tetrachloro-p-benzoquinone in presence of fused sodium acetate as condensing agent under microwave irradiation without any solvent. All the synthesized compounds were tested for their antibacterial and antitumour activity using standard drugs.
Batra
Manoj
M
Department of Pure and Applied Chemistry, Maharshi Dayanand Saraswati University, Ajmer 305 009, India. manojbatra05@rediffmail.com
Kriplani
Prashant
P
Batra
Chhavi
C
Ojha
K G
KG
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D016227:Benzoquinones / Q000138:chemical synthesis* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000188:drug therapy*; D051379:Mice; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014407:Tumor Cells, Cultured
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D016227:Benzoquinones; C004532:quinone