title: Correlation of biological activity with active site binding modes of geminal disulfone HIV-1 integrase inhibitors.
authors.affiliation: Department of Chemistry, University of California, Davis, CA 95616, USA.
authors.forename: D Christopher
authors.initials: DC
authors.lastname: Meadows
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Tantillo
authors.forename: Jacquelyn
authors.initials: J
authors.lastname: Gervay-Hague
mesh_terms: D000818:Animals; D001665:Binding Sites; D002384:Catalysis; D019427:HIV Integrase / Q000737:chemistry / Q000378:metabolism*; D019428:HIV Integrase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology*; D006801:Humans; D006860:Hydrogen Bonding; D008958:Models, Molecular; D013450:Sulfones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D019428:HIV Integrase Inhibitors; D013450:Sulfones; D019427:HIV Integrase