Duchenne's cardiomyopathy: two case reports.
We describe two cases of Duchenne's cardiomyopathy with severe cardiac dysfunction, sporadic episodes of myoglobinuria induced by effort and increased levels of serum creatine kinase. Very mild signs of skeletal myopathy were clinically evident. Left ventriculography showed diffuse severe hypokinesia. Skeletal muscle biopsy demonstrated a dystrophic process. The patients had no familial background of the disease. These 2 patients might have a sporadic inheritance pattern with severe cardiac involvement.
Guo
Hangyuan
H
Department of Cardiology, Shaoxing People's Hospital, First Affiliated Hospital of Medical College, Shaoxing University, Shaoxing, Zhejiang, China. ghangyuan@hotmail.com
Shen
Jianyao
J
Lee
Jong-Dae
JD
D000293:Adolescent; D000328:Adult; D009202:Cardiomyopathies / Q000097:blood / Q000150:complications / Q000473:pathology* / Q000652:urine; D006801:Humans; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000097:blood / Q000150:complications / Q000473:pathology* / Q000652:urine