title: MicroRNA protocols. Perspectives.
abstract: The discoveries of microRNAs (miRNAs), a class of noncoding RNAs that can regulate gene expression by translational repression, have opened a new avenue on gene modulation in mammalian cells. Conceivably, this highly effective method of modulation of gene expression would be exploited for numerous prospectives, including human, therapeutics. This chapter offers some perspective, with emphasis on areas that can be further developed.
authors.affiliation: Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
authors.forename: Shao-Yao
authors.initials: SY
authors.lastname: Ying
authors.forename: Donald C
authors.initials: DC
authors.lastname: Chang
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Miller
authors.forename: Shi-Lung
authors.initials: SL
authors.lastname: Lin
mesh_terms: D000818:Animals; D005544:Forecasting; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000502:physiology*; D012106:Research
chemical_list: D035683:MicroRNAs