title: Endometrial thickness and volume by three-dimensional ultrasound one week after embryo transfer to detect pregnancy.
abstract: OBJECTIVE
  Determine if the evaluation of endometrium one week after embryo transfer can predict pregnancy.
  
  
  METHODS
  Endometrial volume and thickness were evaluated by three-dimensional ultrasound in 40 patients one week after embryo transfer. These results were compared to serum pregnancy test performed one week later.
  
  
  RESULTS
  Twenty two patients have achieved pregnancy. A significant difference was found for endometrial volume: 6.49+/-1.97 mL vs. 3.40+/-1.11 mL (pregnant vs. not pregnant); and thickness: 11.15+/-2.75 mm vs. 9.77+/-1.85 mm. The ROC curve was used to detect the best cutoff values: endometrial volume of 3.48 mL (sensitivity-100%, specificity-68.2%) and endometrial thickness of 10.3 mm (sensitivity-72.2%, specificity-77.3%). The area under curve was significant higher for endometrial volume (0.909 vs. 0.745, P=0.027). No pregnancy was achieved in women who had an endometrial volume <3.8 mL (15 patients) or thickness < 7.9 mm (3 patients).
  
  
  CONCLUSIONS
  The endometrial volume and thickness were significant higher in pregnant women and this difference was more prominent for endometrial volume.
authors.affiliation: Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brasil. wpmartins@gmail.com
authors.forename: Wellington
authors.initials: W
authors.lastname: de Paula Martins
authors.forename: Rui Alberto
authors.initials: RA
authors.lastname: Ferriani
authors.forename: Rosana Maria
authors.initials: RM
authors.lastname: dos Reis
authors.forename: Carolina Oliveira
authors.initials: CO
authors.lastname: Nastri
authors.forename: Francisco Mauad
authors.initials: FM
authors.lastname: Filho
mesh_terms: D000328:Adult; D001938:Brazil; D004624:Embryo Transfer; D004717:Endometrium / Q000000981:diagnostic imaging*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D011247:Pregnancy; D011258:Pregnancy Tests / Q000379:methods*; D012372:ROC Curve; D014463:Ultrasonography