SPEED: a molecular-evolution-based database of mammalian orthologous groups.
BACKGROUND
The abundance of nucleotide sequence information available has expanded horizons of inquiry for molecular evolution; however, the full potential of whole-genome analysis has not been realized because of inadequate tools. Here, we present one of the first toolkits to aid multidisciplinary high-throughput analysis.


CONCLUSIONS
SPEED was created to integrate molecular evolutionary data with existing genetic resources and provide a straightforward user interface to 17,352 orthologous gene groups, containing representatives from eight mammalian species and an avian outgroup.


BACKGROUND
See http://bioinfobase.umkc.edu/speed/ for access.
Vallender
Eric J
EJ
Department of Human Genetics and Committee on Genetics, Howard Hughes Medical Institute, University of Chicago 920 East 58th Street, Chicago, IL 60637, USA.
Paschall
Justin E
JE
Malcom
Christine M
CM
Lahn
Bruce T
BT
Wyckoff
Gerald J
GJ
D000465:Algorithms; D000818:Animals; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D030562:Databases, Protein; D019143:Evolution, Molecular; D016678:Genome; D006801:Humans; D010802:Phylogeny; D016415:Sequence Alignment; D012984:Software