Biocompatibility of resin-based dental materials applied as liners in deep cavities prepared in human teeth.
BACKGROUND
Since only a few data have been published concerning the effects of resinous dental materials on the pulp-dentin complex, the aim of this study was to evaluate the biocompatibility of resin-based materials applied as liners in deep cavities prepared in human teeth.


METHODS
After preparing class V cavities, the following dental materials were applied on the axial walls: group 1, Vitrebond (VIT; 3M ESPE); group 2, Ultra-Blend Plus (UBP; Untradent); and group 3, Clearfil SE Bond (CSEB; Kuraray). In group 4 (control), the hard-setting calcium hydroxide cement Dycal (CH; Caulk/Dentsply) was used. The teeth extracted at 7 days or between 30 and 85 days after the clinical procedures were processed for histological evaluation.


RESULTS
For all the experimental and control groups, most of specimens exhibited no pulpal response or slight inflammatory reaction associated with slight tissue disorganization at 7-day period. Moderate inflammatory pulpal response occurred only in one tooth (RDT = 262 microm) of group 3 in which transdentinal diffusion of resin components was observed.


CONCLUSIONS
The resin-based dental cements VIT and UBP as well as the bonding agent CSEB presented acceptable biocompatibility when applied in deep cavities prepared in sound human teeth.
de Souza Costa
Carlos Alberto
CA
Araraquara School of Dentistry, University of São Paulo State-UNESP, Rua Humaitá, 1680 CEP: 14.801-903, CP: 331, Araraquara, São Paulo, Brazil. casouzac@foar.unesp.br
Teixeira
Hilcia Mezzalira
HM
Lopes do Nascimento
Alexandre Batista
AB
Hebling
Josimeri
J
D000293:Adolescent; D001672:Biocompatible Materials / Q000009:adverse effects*; D002648:Child; D003736:Dental Cavity Lining / Q000379:methods*; D003764:Dental Materials / Q000009:adverse effects*; D006801:Humans; D008422:Materials Testing; D019279:Resin Cements / Q000009:adverse effects*; D014070:Tooth / Q000166:cytology / Q000601:surgery
D001672:Biocompatible Materials; D003764:Dental Materials; D019279:Resin Cements