[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed].
The European/Australasian stroke prevention in reversible ischaemia trial (ESPRIT) confirms that long-term administration of the combination acetylsalicylic acid and dipyridamole is more effective than acetylsalicylic acid in reducing the risk of vascular events after cerebral ischaemia of arterial origin. The results of this study in combination with the results of previous studies have provided sufficient evidence for the use of this therapy in clinical practice.
Luijckx
G J
GJ
Universitair Medisch Centrum Groningen, afd. Neurologie, Postbus 30.001, 9700 RB Groningen. g.j.luijckx@neuro.umcg.nl
De Keyser
J H A
JH
de Keyser
J H A
JH
D000925:Anticoagulants / Q000627:therapeutic use*; D001241:Aspirin / Q000008:administration & dosage*; D002544:Cerebral Infarction / Q000517:prevention & control*; D004176:Dipyridamole / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D002546:Ischemic Attack, Transient / Q000517:prevention & control*; D011315:Preventive Medicine; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000925:Anticoagulants; D014665:Vasodilator Agents; D004176:Dipyridamole; D001241:Aspirin