[Progress of research on Chinese material medica serum and hepatic stellate cells].
The activation and proliferation of hepatic stellate cells (HSCs) is the central link in the formation and progression of liver fibrosis. From the research of serum pharmacological method of Chinese material medica, we found Chinese material medica serum could interfere in the formation and progression of liver fibrosis. This paper reviewed the progress on Chinese material medica serum and HSCs. The authors pointed out Chinese material medica serum could effect on the activation, proliferation, contraction and apoptosis of HSCs, which probably is an effective therapy for liver fibrosis.
Yang
Chun
C
Department of Digestive System, Affiliated Hospital of Luzhou Medical College, Sichuan 646000. xiaoyang19777@yahoo.com.cn
Li
Chang-ping
CP
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D022781:Hepatocytes / Q000166:cytology* / Q000187:drug effects*; D006801:Humans; D008103:Liver Cirrhosis / Q000517:prevention & control; D044967:Serum
D004365:Drugs, Chinese Herbal