title: Readily available phosphine-phosphoramidite ligands for highly efficient Rh-catalyzed enantioselective hydrogenations.
abstract: A new family of air- and moisture-stable phosphine-phosphoramidite ligands (PEAPhos) has been prepared from commercially available and inexpensive (S)-alpha-phenylethylamine through a two- or three-step transformation and successfully applied in the rhodium-catalyzed enantioselective hydrogenations of a variety of substrates, in which up to 99.9% ee was obtained for all of these kinds of substrates.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
authors.forename: Jia-Di
authors.initials: JD
authors.lastname: Huang
authors.forename: Xiang-Ping
authors.initials: XP
authors.lastname: Hu
authors.forename: Zheng-Chao
authors.initials: ZC
authors.lastname: Duan
authors.forename: Qing-Hen
authors.initials: QH
authors.lastname: Zeng
authors.forename: Sai-Bo
authors.initials: SB
authors.lastname: Yu
authors.forename: Jun
authors.initials: J
authors.lastname: Deng
authors.forename: Dao-Yong
authors.initials: DY
authors.lastname: Wang
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Zheng