Unusual macular lesions in a patient with neurofibromatosis type-1.
BACKGROUND
Retinal involvement in neurofibromatosis type-1 (NF-1) is rare.


METHODS
We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity.


RESULTS
Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions.


CONCLUSIONS
Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.
McLoone
Eibhlín M
EM
Department of Ophthalmology, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. eibhlin_mcloone@hotmail.com
Buchanan
Trevor A S
TA
D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D019572:Retinal Neoplasms / Q000175:diagnosis*; D014792:Visual Acuity