title: [Gastroduodenal complications associated with non-steroidal anti-inflammatory drugs in Slovak Republic: results of one-year prospective study].
abstract: The aim of the one-year prospective study was to estimate the prevalence of non-steroidal anti-inflammatory drugs using in patients with symptomatic gastroduodenal ulcers, the upper gastrointestinal bleeding and perforation (PUB--perforation, ulcer, bleeding). Among of 326 patients with PUB, prevalence of non-steroidal anti-inflammatory drugs using was 60%. In the group of 194 patients with non-steroidal antiinflammatory drugs induced PUB, 49% patients took aspirin, 38% non-aspirin non-steroidal anti-inflammatory drugs and 13% their combination. Low dosing aspirin (daily dosis < or =200 mg) was associated with PUB in 21% of patients. Age higher than 60 years and women had statisticaly signiticant higher prevalence of non-steroidal anti-inflammatory drugs induced PUB.
authors.affiliation: Katedra reumatológie Fakulty zdravotníctva a pecializacných stúdií Slovenskej zdravotníckej univerzity, Bratislava, Slovenskdá republika. rybar@nurch.sk
authors.forename: I
authors.initials: I
authors.lastname: Rybár
authors.forename: M
authors.initials: M
authors.lastname: Hlísta
authors.forename: P
authors.initials: P
authors.lastname: Masaryk
authors.forename: J
authors.initials: J
authors.lastname: Rovenský
authors.forename: R
authors.initials: R
authors.lastname: Hyrdel
authors.forename: M
authors.initials: M
authors.lastname: Kriska
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000139:chemically induced*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal