Topography of long- and middle-wavelength sensitive cone opsin gene expression in human and Old World monkey retina.
The topographical distributions of the relative ratio of long- (L) and middle- (M) wavelength sensitive cone opsin messenger RNA (mRNA) in human and baboon retinas were mapped using real-time polymerase chain reaction. The L:M mRNA ratio increased in a central-to-peripheral gradient in both species, being quite pronounced for humans.
Neitz
Maureen
M
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. mneitz@mcw.edu
Balding
Shawn D
SD
McMahon
Carrie
C
Sjoberg
Stacy A
SA
Neitz
Jay
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D015870:Gene Expression / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D048530:Papio anubis; D012333:RNA, Messenger / Q000378:metabolism; D012160:Retina / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D017299:Rod Opsins / Q000235:genetics / Q000378:metabolism*; D012737:Sex Factors
D012333:RNA, Messenger; D017299:Rod Opsins; C095855:long-wavelength opsin; C095854:middle-wavelength opsin