title: [Epidemiology of type 1 diabetes in children and adolescents aged less than 15 years in the provinces of Castilla y León].
abstract: BACKGROUND
  The incidence of type 1 diabetes shows wide geographical variability and heterogeneity. The aim of this study was to determine the incidence and prevalence of type 1 diabetes in children and adolescents ages less than 15 years in the different provinces of Castilla-León.
  
  
  METHODS
  To determine incidence, all new cases of type 1 diabetes with onset under 15 years of age in 2003-2004 were obtained. Incidence was expressed as the crude value with the corresponding confidence interval and as standardized incidence. The capture-recapture method was used to calculate the completeness of ascertainment. To determine prevalence, all cases of type 1 diabetes in persons ages less than 15 years at 31 December 2004 were obtained.
  
  
  RESULTS
  Incidence showed wide variability among the different provinces of Castilla-León. The highest values were found in Segovia (38.77/100,000/year), Valladolid (32.07/100,000/ year) and Avila (23.21/100,000/year) and the lowest in Zamora (8.14/100,000/year). Incidences were highest in the 5-9 years age group in all provinces except Burgos. Prevalence was highest in Segovia (1.54/1,000), Valladolid (1.41/1,000), Avila (1.38/1,000) and Zamora (1.32/1,000) and lowest in Burgos (0.91/1,000).
  
  
  CONCLUSIONS
  Castilla-León seems to have one of the highest incidences of type 1 diabetes in Spain; several of its provinces have values similar to those in Northern Europe.
authors.affiliation: Hospital Clínico Universitario de Valladolid, Spaña. pilarbahilloc@yahoo.es
authors.forename: Maria P
authors.initials: MP
authors.lastname: Bahíllo Curieses
authors.forename: F
authors.initials: F
authors.lastname: Hermoso López
authors.forename: J A
authors.initials: JA
authors.lastname: García Fernández
authors.forename: C
authors.initials: C
authors.lastname: Ochoa Sangrador
authors.forename: J
authors.initials: J
authors.lastname: Rodrigo Palacios
authors.forename: S I
authors.initials: SI
authors.lastname: de la Torre Santos
authors.forename: J M
authors.initials: JM
authors.lastname: Marugán de Miguelsanz
authors.forename: F
authors.initials: F
authors.lastname: Manzano Recio
authors.forename: J
authors.initials: J
authors.lastname: García Velázquez
authors.forename: T J
authors.initials: TJ
authors.lastname: Lema Garret
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D015995:Prevalence; D013030:Spain / Q000453:epidemiology