title: Review of 86 patients with myelodysplasia and neurogenic bladder who underwent sigmoidocolocystoplasty and were followed more than 10 years.
abstract: OBJECTIVE
  We reviewed the long-term outcome of sigmoidocolocystoplasty.
  
  
  METHODS
  The records of 86 patients who underwent sigmoidocolocystoplasty with a followup of more than 10 years were reviewed, focusing on histopathology, renal function, vesicoureteral reflux, bladder stones and urinary continence. We developed a urinary continence evaluation score, calculated as the postoperative minus the preoperative urinary continence score, including 0-incontinence, 1-severe leakage, 2-moderate leakage, 3-mild leakage, 4-almost dry and 5-dry, for patient self-assessment of urinary continence. A score of 2 or more meant improvement and a score of less than 2 meant no improvement.
  
  
  RESULTS
  Mean followup was 13.1 years (range 10 to 21). Histopathology showed inflammation in all cases, hyperplasia in 9 and metaplasia in 4. In 80 of 86 cases creatinine clearance was normal. Ureteral reimplantation had been performed before sigmoidocolocystoplasty in 9 cases (13 kidneys) for grades III to V vesicoureteral reflux, which recurred as grade I in 1 (1 kidney). Ureteral reimplantation was performed during sigmoidocolocystoplasty in 31 cases (58 kidneys) and grades I to II vesicoureteral recurred in 5 (6 kidneys). Of the remaining 44 sigmoidocolocystoplasty cases there were 2 (2 kidneys) of grade I vesicoureteral reflux. On (99m)technetium-dimercapto-succinic acid scintigraphy there was increased renal scarring in 8 cases. Bladder stones were identified in 18 of 86 cases during followup but they were absent at review. The urinary continence evaluation score showed improvement in 61 cases and no improvement in 25.
  
  
  CONCLUSIONS
  Our results suggest that sigmoidocolocystoplasty is safe and effective in the long term.
authors.affiliation: Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Yamataka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kaneyama
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kato
authors.forename: Geoffrey J
authors.initials: GJ
authors.lastname: Lane
authors.forename: Takeshi
authors.initials: T
authors.lastname: Miyano
mesh_terms: D000293:Adolescent; D000328:Adult; D000714:Anastomosis, Surgical; D002648:Child; D002675:Child, Preschool; D012809:Colon, Sigmoid / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008297:Male; D009436:Neural Tube Defects / Q000150:complications*; D012008:Recurrence; D001743:Urinary Bladder / Q000601:surgery*; D001744:Urinary Bladder Calculi / Q000150:complications; D001750:Urinary Bladder, Neurogenic / Q000150:complications / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D014554:Urination; D014563:Urodynamics; D014718:Vesico-Ureteral Reflux / Q000150:complications