title: Use of the BIOMIC Video System to evaluate the susceptibility of clinical yeast isolates to fluconazole and voriconazole by a disk diffusion method.
abstract: The ARTEMIS Global Antifungal Susceptibility Program provides the collection of epidemiological data and the results of the fluconazole and voriconazole susceptibility testing of yeast isolates. Participating in this study, a total of 7318 clinical yeast isolates were tested from different geographical areas in Hungary in the period 2001 to 2003. The species isolated most frequently was C. albicans (68.8%), followed by C. glabrata (11.8%), C. tropicalis (5.7%) and C. krusei (4.6%). Isolates of C. albicans, C. kefyr, C. lusitaniae, C. tropicalis and C. parapsilosis were highly susceptible to fluconazole (78.9-100%). The rates of isolation of fluconazole-resistant C. glabrata and C. krusei were higher in our study than the global mean in 2001 (28.2% and 87.5% vs. 18.3% and 70.2%, respectively). Differences were detected in the distribution of fluconazole-susceptibility data of C. glabrata isolates in the different counties of Hungary: most of the resistant isolates were observed in the eastern part of the country.
authors.affiliation: Department of Clinical Microbiology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
authors.forename: Ilona
authors.initials: I
authors.lastname: Dóczi
authors.forename: Gy
authors.initials: G
authors.lastname: Mestyán
authors.forename: Erzsébet
authors.initials: E
authors.lastname: Puskás
authors.forename: Radka
authors.initials: R
authors.lastname: Nikolova
authors.forename: I
authors.initials: I
authors.lastname: Barcs
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Nagy
mesh_terms: D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology; D015725:Fluconazole / Q000494:pharmacology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008826:Microbial Sensitivity Tests / Q000379:methods*; D018715:Microscopy, Video / Q000379:methods; D011743:Pyrimidines / Q000494:pharmacology*; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
chemical_list: D011743:Pyrimidines; D014230:Triazoles; D015725:Fluconazole; D065819:Voriconazole