title: Successful treatment of acquired amegakaryocytic thrombocytopenia with cyclosporine in adult onset Still's disease.
abstract: Acquired amegakaryocytic thrombocytopenia (AAT) is a rare disorder, characterized by severe thrombocytopenia and selective, marked decrease or absence of megakaryocytes in the bone marrow. We describe a 29-year-old female with adult onset Still's disease preceding a diagnosis of AAT and autoimmune hemolytic anemia, which was successfully treated with cyclosporine. This is the first case of AAT in a patient with adult onset Still's disease.
authors.affiliation: Division of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University, Seoul, 133-792, South Korea.
authors.forename: Min-Young
authors.initials: MY
authors.lastname: Her
authors.forename: Tae-Hwan
authors.initials: TH
authors.lastname: Kim
authors.forename: Hyun-Kyu
authors.initials: HK
authors.lastname: Chang
authors.forename: Woong-Soo
authors.initials: WS
authors.lastname: Lee
authors.forename: Dae-Hyun
authors.initials: DH
authors.lastname: Yoo
mesh_terms: D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000188:drug therapy*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008533:Megakaryocytes / Q000187:drug effects; D017713:Platelet Transfusion; D016706:Still's Disease, Adult-Onset / Q000150:complications / Q000188:drug therapy*; D013921:Thrombocytopenia / Q000150:complications / Q000188:drug therapy*
chemical_list: D018501:Antirheumatic Agents; D016572:Cyclosporine