title: Acute fright induces onset of symptoms in vanishing white matter disease-case report.
abstract: Vanishing white matter disease is a newly recognised leukoencephalopathy of identified genetic background, characterised by cystic degeneration and progressive vanishing of white matter. The characteristic clinical symptoms are spasticity and ataxia with relatively preserved cognitive functions. A characteristic feature of the disease is the occurrence of the symptoms after a physical stress situation such as mild head trauma or febrile infection. We would like to present a case of a 6-year-old girl whose first symptoms of the disease occurred after being frightened by a horse.
authors.affiliation: Department of Neurology and Epileptology, The Children's Memorial Health Institute, Warsaw, Poland. magdalen_ka@tlen.pl
authors.forename: M
authors.initials: M
authors.lastname: Kaczorowska
authors.forename: D
authors.initials: D
authors.lastname: Kuczynski
authors.forename: E
authors.initials: E
authors.lastname: Jurkiewicz
authors.forename: G C
authors.initials: GC
authors.lastname: Scheper
authors.forename: M S
authors.initials: MS
authors.lastname: van der Knaap
authors.forename: S
authors.initials: S
authors.lastname: Jozwiak
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000235:genetics* / Q000473:pathology*; D002648:Child; D004247:DNA / Q000235:genetics; D005239:Fear / Q000502:physiology*; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology / Q000473:pathology; D006801:Humans; D009128:Muscle Spasticity / Q000209:etiology / Q000473:pathology; D009154:Mutation / Q000235:genetics
chemical_list: D004247:DNA