Long-term local control of recurrent adenoid cystic carcinoma in the parotid gland with radiotherapy and intraarterial infusion chemotherapy.
We report a case of postoperative recurrence of adenoid cystic carcinoma in the left parotid gland treated with radiotherapy and arterial infusion chemotherapy. A 52-year-old woman had a history of surgical resection for an adenoid cystic carcinoma arising from the left parotid gland 25 years before. Despite two reoperations for local recurrence after the initial surgery, she had a third local recurrence in the remnant of the left parotid gland. The patient was treated with a concurrent combination of radiotherapy (60 Gy/30F) and intraarterial infusion chemotherapy with carboplatin (750 mg/30 days) from which she obtained a complete response. The patient has remained free of local progression 54 months after treatment. Radiotherapy and arterial infusion chemotherapy is effective treatment for local recurrence of adenoid cystic carcinoma in the head and neck.
Terashima
Koutarou
K
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, Japan.
Shioyama
Yoshiyuki
Y
Nakamura
Katsumasa
K
Ohga
Saiji
S
Nomoto
Satoshi
S
Yamaguchi
Toshihiro
T
Toba
Takashi
T
Yoshitake
Tadamasa
T
Yabuuchi
Hidetake
H
Nakashima
Torahiko
T
Terashima
Hiromi
H
Honda
Hiroshi
H
D000970:Antineoplastic Agents / Q000008:administration & dosage; D016190:Carboplatin / Q000008:administration & dosage*; D003528:Carcinoma, Adenoid Cystic / Q000188:drug therapy* / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D010307:Parotid Neoplasms / Q000628:therapy*; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D016190:Carboplatin