Exclusive intrapulmonary lepidic growth of a malignant pleural mesothelioma presenting with pneumothorax and involving the peritoneum.
We report a rare case of malignant pleural mesothelioma presenting clinically with pneumothorax and histologically with an exclusive intrapulmonary lepidic growth. Neither intrathoracic nodules nor pleural thickening were found. The patient subsequently experienced acute abdominal pain with peritonitis and intestinal occlusion by peritoneal mesothelioma. The morphologic clues leading to the correct diagnosis of mesothelioma with prominent intrapulmonary growth are briefly discussed.
Rossi
Giulio
G
Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy. rossi.giulio@policlinico.mo.it
Cavazza
Alberto
A
Turrini
Ercole
E
Costantini
Matteo
M
Casali
Christian
C
Morandi
Uliano
U
Dallari
Rossano
R
D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007421:Intestine, Small / Q000473:pathology / Q000601:surgery; D008168:Lung / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000737:chemistry / Q000556:secondary*; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000556:secondary*; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000556:secondary*; D010997:Pleural Neoplasms / Q000737:chemistry / Q000473:pathology*; D011030:Pneumothorax / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor