Antibiotic susceptibility and molecular diversity of Bacillus anthracis strains in Chad: detection of a new phylogenetic subgroup.
We genotyped 15 Bacillus anthracis isolates from Chad, Africa, using multiple-locus variable-number tandem repeat analysis and three additional direct-repeat markers. We identified two unique genotypes that represent a novel genetic lineage in the A cluster. Chadian isolates were susceptible to 11 antibiotics and free of 94 antibiotic resistance genes.
Maho
Angaya
A
Laboratoire de Recherches Vétérinaires et Zootechniques, BP433 Farcha, N'Djaména, Chad.
Rossano
Alexandra
A
Hächler
Herbert
H
Holzer
Anita
A
Schelling
Esther
E
Zinsstag
Jakob
J
Hassane
Mahamat H
MH
Toguebaye
Bhen S
BS
Akakpo
Ayayi J
AJ
Van Ert
Matthew
M
Keim
Paul
P
Kenefic
Leo
L
Frey
Joachim
J
Perreten
Vincent
V
D000881:Anthrax / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001408:Bacillus anthracis / Q000145:classification* / Q000187:drug effects* / Q000235:genetics; D002596:Chad; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests; D018598:Minisatellite Repeats / Q000235:genetics; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012091:Repetitive Sequences, Nucleic Acid
D000900:Anti-Bacterial Agents