title: Computed tomography scans of intra-abdominal fat, anthropometric measurements, and 3 nonobese metabolic risk factors.
abstract: The present cross-sectional study of 46 adult Danish white men and women aimed to evaluate association between intra-abdominal obesity, 4 anthropometric measurements of obesity, and combinations of 3 nonobese metabolic risk factors: systolic blood pressure of 130 mm Hg or higher, serum triglyceride concentration of more than 1.7 mmol/L, and fasting capillary blood glucose concentration of 5.6 mmol/L or more. For 80% of the subjects, intra-abdominal fat on a computed tomography scan of the abdomen using a cutoff limit of more than 144 cm(2) gave a correct classification of combinations of at least 2 of the 3 metabolic risk factors. Body mass index and waist circumference were better markers of intra-abdominal obesity than waist-to-hip ratio in receiver operating characteristic analyses (P = .0035). Body mass index of more than 26 kg/m(2) and waist circumference of more than 0.92 m classified 76% and 74% of the subjects correctly regarding combinations of the 3 nonobese metabolic risk factors. Intra-abdominal obesity was significantly stronger associated with the combinations than a raised waist-to-hip ratio (P = .016). Both body mass index and waist circumference may be used as markers of intra-abdominal obesity, whereas waist-to-hip ratio was significantly inferior. Correspondingly, both body mass index and waist circumference were better than waist-to-hip ratio to indicate combinations of the 3 nonobese metabolic risk factors.
authors.affiliation: Department of Internal Medicine, Herning Hospital, DK-7400 Herning, Denmark. feve@post5.tele.dk
authors.forename: Finn E
authors.initials: FE
authors.lastname: von Eyben
authors.forename: Ejvind
authors.initials: E
authors.lastname: Mouritsen
authors.forename: Jan
authors.initials: J
authors.lastname: Holm
authors.forename: Georg
authors.initials: G
authors.lastname: Dimcevski
authors.forename: Paulius
authors.initials: P
authors.lastname: Montvilas
authors.forename: Gabriel
authors.initials: G
authors.lastname: Suciu
mesh_terms: D050153:Abdominal Fat / Q000000981:diagnostic imaging*; D000328:Adult; D000886:Anthropometry; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D016022:Case-Control Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000000981:diagnostic imaging* / Q000453:epidemiology; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood; D012372:ROC Curve; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio
chemical_list: D001786:Blood Glucose; D017395:Plasminogen Activator Inhibitor 1; D014280:Triglycerides; D005340:Fibrinogen