title: Cotranslocational degradation: utilitarianism in the ER stress response.
abstract: Recently, a new layer of the unfolded protein response was discovered that supports the cotranslocational degradation of nascent chains stalled in endoplasmic reticulum translocons (Oyadomari et al., 2006).
authors.affiliation: Department of Biochemistry and Molecular Biology, Program in Molecular and Cellular Biology, University of Massachusetts, 710 North Pleasant Street, Amherst, Massachusetts 01003, USA.
authors.forename: Bradley R
authors.initials: BR
authors.lastname: Pearse
authors.forename: Daniel N
authors.initials: DN
authors.lastname: Hebert
mesh_terms: D000818:Animals; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D008954:Models, Biological; D014176:Protein Biosynthesis / Q000502:physiology*; D017510:Protein Folding; D011506:Proteins / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D008565:Membrane Proteins; D011506:Proteins