Functional imaging in CT.
Fast data acquisition imaging technologies such as modern computed tomography (CT) allow contrast agents to be used as tracers and nuclear medicine methodology may be used to derive a variety of functional/physiological information from dynamic CT. This article describes the theoretical basis and some practical applications of this idea including the measurement of perfusion, capillary permeability, vascular volumes, renal function and tumour responses to therapy.
Dawson
Peter
P
Department of Imaging, UCL Hospitals, Euston Road, London NW1 2BU, United Kingdom. Peter.Dawson@uclh.org <Peter.Dawson@uclh.org>
D019540:Area Under Curve; D003287:Contrast Media / Q000493:pharmacokinetics*; D006801:Humans; D017613:Iodine Compounds / Q000493:pharmacokinetics; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003287:Contrast Media; D017613:Iodine Compounds