Impact of prenatal urinomas in patients with posterior urethral valves and postnatal renal function.
OBJECTIVE
Posterior urethral valves (PUV) are a common cause of lower urinary tract obstruction. Renal failure occurs in approximately one third of the cases. It is debated whether urinoma formation is a protective mechanism to reduce pressure-related impairment of renal function. The aim of our study was to determine if urinoma formation is able to preserve renal function on the side of the urinoma.


METHODS
Five male patients diagnosed with posterior urethral valves and uni- or bilateral urinoma formation were reviewed. Renal function was assessed by serum creatinine level at days 4-7 and at two months, in addition to dimercaptosuccinylacid (DMSA) scintigraphy at 4-6 weeks postnatal age.


RESULTS
Impaired renal function occurred unilaterally in four patients, two had bilateral urinoma formation, and the other two boys presented with unilateral urinoma, one with preserved renal function ipsilateral to the urinoma and the other on the contralateral side. Urinary ascites was detected in three patients, all underwent antenatal centesis.


CONCLUSIONS
No association was found between renal function and urinoma formation in patients with PUV.
Kleppe
Stefanie
S
Department of Neonatology, University of Bonn, Bonn, Germany.
Schmitt
Joachim
J
Geipel
Annegret
A
Gembruch
Ullrich
U
Hansmann
Manfred
M
Bartmann
Peter
P
Franke
Ingo
I
Heep
Axel
A
D001201:Ascites / Q000503:physiopathology*; D005315:Fetal Diseases / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014521:Urethra / Q000002:abnormalities*; D053584:Urinoma / Q000000981:diagnostic imaging / Q000503:physiopathology*