Can cognitive behavioral therapy reduce relapse rates of depression after ECT? a preliminary study.
OBJECTIVE
The goal of this study was to explore the potential of providing cognitive behavioral therapy (CBT) after an index course of electroconvulsive therapy (ECT) for depression to improve long-term outcome.


METHODS
The Beck Depression Inventory (BDI) and Clinical Global Impression (CGI) scale were used to assess depression and treatment outcome for 6 patients who received 12 weeks of CBT after an index course and concurrent with a continuation course of ECT.


RESULTS
Patients either maintained their response or showed decreased depressive symptoms at the 6-month post-index ECT evaluation. At the 9-month follow-up, 5 of 6 patients had BDI scores below their post-index ECT scores. The CGIs were rated "much improved" or "very much improved" by 5 patients at the termination of CBT. All 6 patients maintained or improved their CGIs at the 6-month follow-up.


CONCLUSIONS
These results provide preliminary evidence that CBT after ECT is feasible and may extend the antidepressant effects ofECT.
Fenton
Lisa
L
Yale Depression Research Program, Yale University School of Medicine, New Haven, CT 06511, USA.
Fasula
Madonna
M
Ostroff
Robert
R
Sanacora
Gerard
G
D000368:Aged; D015928:Cognitive Behavioral Therapy; D003865:Major Depressive Disorder / Q000517:prevention & control* / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005240:Feasibility Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D055502:Secondary Prevention; D016896:Treatment Outcome