Diffuse dermal angiomatosis.
Diffuse dermal angiomatosis (DDA) is an acquired, benign vascular proliferation characterized clinically by poorly circumscribed, violaceous, livedoid plaques with frequent ulceration. Histologically, a diffuse interstitial proliferation of CD31-positive endothelial cells is present within the papillary and reticular dermis. Endothelial atypia, atypical mitoses, and vasculitis are lacking. We describe a case of DDA in a 53-year-old man with peripheral vascular atherosclerosis that resolved following revascularization. Early correction of the associated ischemic peripheral vascular disease promotes resolution of this unusual clinicopathologic entity.
Draper
Bradley K
BK
Division of Dermatology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. draperclan@juno.com
Boyd
Alan S
AS
D000328:Adult; D000798:Angiomatosis / Q000209:etiology* / Q000473:pathology*; D050197:Atherosclerosis / Q000150:complications* / Q000601:surgery; D003251:Constriction, Pathologic; D003324:Coronary Artery Disease / Q000150:complications; D042783:Endothelial Cells / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000150:complications; D007083:Iliac Artery / Q000473:pathology / Q000601:surgery; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology*; D015607:Stents
D019408:Platelet Endothelial Cell Adhesion Molecule-1