title: Distachyasin: A new antioxidant metabolite from the leaves of Carex distachya.
abstract: A novel antioxidant prenylated stilbenoid, distachyasin, has been isolated from the leaves of Carex distachya. Its structure has been elucidated on the basis of the spectroscopic characteristics. Bidimensional NMR, and crystallographic data and computational calculations have furnished important data useful for the characterization and the stereochemistry of the molecule. The compound has a tetracyclic skeleton derived from carexane. The compound has been assayed, for the antioxidant activity, by measuring its capacity to scavenge the H(2)O(2), nitric oxide, superoxide radical and to inhibit formation of TBARS (thiobarbituric acid reactive species).
authors.affiliation: Dipartimento di Scienze della Vita, Seconda Università degli studi di Napoli, via Vivaldi 43, 81100 Caserta, Italy. antonio.fiorentino@unina2.it <antonio.fiorentino@unina2.it>
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiorentino
authors.forename: Brigida
authors.initials: B
authors.lastname: D'Abrosca
authors.forename: Severina
authors.initials: S
authors.lastname: Pacifico
authors.forename: Rosa
authors.initials: R
authors.lastname: Iacovino
authors.forename: Claudio
authors.initials: C
authors.lastname: Mastellone
authors.forename: Benedetto
authors.initials: B
authors.lastname: Di Blasio
authors.forename: Pietro
authors.initials: P
authors.lastname: Monaco
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000378:metabolism*; D031255:Carex Plant / Q000737:chemistry* / Q000378:metabolism*; D005609:Free Radicals / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D009573:Nitrites / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry / Q000378:metabolism; D011083:Polycyclic Compounds / Q000737:chemistry* / Q000378:metabolism*; D013267:Stilbenes / Q000737:chemistry* / Q000378:metabolism*; D013481:Superoxides / Q000737:chemistry; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D009573:Nitrites; D011083:Polycyclic Compounds; D013267:Stilbenes; D017392:Thiobarbituric Acid Reactive Substances; C515888:distachyasin; D013481:Superoxides; D006861:Hydrogen Peroxide