title: Infrared and DNA-binding on ultraviolet and fluorescence spectra of new copper and zinc complexes with a naringenin Schiff-base ligand.
abstract: A naringenin Schiff-base ligand (H(3)L) and its copper(II) and zinc(II) complexes have been synthesized and characterized by elemental analyses, molar conductivities, (1)H NMR, IR spectra, UV spectra and thermal analyses. The DNA-binding properties of the Cu(II) and Zn(II) complexes have been investigated by fluorescence spectroscopy, ultraviolet spectroscopy and by viscosity measurements. The results indicate that complexes and ligand may bind to DNA by intercalation modes, but the binding affinity of the complexes is much higher than that of the ligand.
authors.affiliation: College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Yan-hua
authors.initials: YH
authors.lastname: Li
authors.forename: Bao-dui
authors.initials: BD
authors.lastname: Wang
authors.forename: Zheng-yin
authors.initials: ZY
authors.lastname: Yang
mesh_terms: D003300:Copper / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry; D006835:Hydrazones / Q000737:chemistry; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014783:Viscosity; D015032:Zinc / Q000737:chemistry
chemical_list: C522617:(4',5,7-trihydroxyflavanone benzoyl hydrazone)copper(II); C522618:(4',5,7-trihydroxyflavanone benzoyl hydrazone)zinc(II); C522616:4',5,7-trihydroxyflavanone benzoyl hydrazone; D044950:Flavanones; D006835:Hydrazones; D008024:Ligands; D009942:Organometallic Compounds; D012545:Schiff Bases; D003300:Copper; D004247:DNA; C005273:naringenin; D015032:Zinc