Role of DNA polymerase IV in Escherichia coli SOS mutator activity.
Constitutive expression of the SOS regulon in Escherichia coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA polymerase V (umuDC gene product). Here we show that a significant fraction of this effect also requires DNA polymerase IV (dinB gene product).
Kuban
Wojciech
W
Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A, 02 106 Warsaw, Poland.
Banach-Orlowska
Magdalena
M
Schaaper
Roel M
RM
Jonczyk
Piotr
P
Fijalkowska
Iwona J
IJ
D019951:DNA Polymerase beta / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D016296:Mutagenesis; D013014:SOS Response, Genetics
D029968:Escherichia coli Proteins; D019951:DNA Polymerase beta