Mechanisms ensuring optimal conditions of implantation and embryo development in the pig.
The paper summarizes results of a series of studies concerning luteolysis and early pregnancy in pigs. The involvement of the oxytocin (OT)/OT receptor system in the mechanism of corpus luteum (CL) protection during early pregnancy as well as the implication of luteinizing hormone (LH) in the endometrial prostaglandin (PG) release and synthesis are described. In addition, the role of leptin in the regulation of ovarian steroidogenesis and the expression of leptin and its receptor (OB-Rb) genes in hypothalamus, pituitary and reproductive tissues are reported. Moreover, a strong emphasis was placed on the mechanism of PGE2 participation in the local endocrine regulations of reproductive processes occurring in the utero-ovarian area as well as on the vascular endothelial growth factor (VEGF) ligand-receptor system in the ovary and uterus.
Przała
Jadwiga
J
Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-718 Olsztyn, Poland. jadwigap@uwm.edu.pl
Gregoraszczuk
Ewa L
EL
Kotwica
Genowefa
G
Stefańczyk-Krzymowska
Stanisława
S
Ziecik
Adam J
AJ
Blitek
Agnieszka
A
Ptak
Anna
A
Rak
Anna
A
Wójtowicz
Anna
A
Kamiński
Tadeusz
T
Siawrys
Gabriela
G
Smolińska
Nina
N
Franczak
Anita
A
Kurowicka
Beata
B
Oponowicz
Agnieszka
A
Wasowska
Barbara
B
Chłopek
Jolanta
J
Kowalczyk
Anna E
AE
Kaczmarek
Monika M
MM
Wacławik
Agnieszka
A
D000818:Animals; D003338:Corpus Luteum / Q000378:metabolism; D015237:Dinoprost / Q000378:metabolism; D015232:Dinoprostone / Q000378:metabolism; D010064:Embryo Implantation / Q000502:physiology*; D047108:Embryonic Development / Q000502:physiology*; D030762:Estrous Cycle / Q000378:metabolism; D005260:Female; D020738:Leptin / Q000378:metabolism / Q000502:physiology; D007986:Luteinizing Hormone / Q000502:physiology; D010053:Ovary / Q000378:metabolism; D011247:Pregnancy; D013552:Swine / Q000502:physiology*; D014599:Uterus / Q000378:metabolism
D020738:Leptin; D007986:Luteinizing Hormone; D015237:Dinoprost; D015232:Dinoprostone