title: Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump.
abstract: We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). In five cardiac-arrested pigs, the outflow cannula of the CP was inserted into the ascending aorta, the inflow cannula in the right atrium. A 30-ml IABP was subsequently placed in the descending aorta. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg per minute by CP alone or by IABP/CP with pressure and flow measured in the right internal carotid artery. The IABP/CP combination converted the flow to pulsatile and increased pulse pressure significantly from 9.1 +/- 1.3 mm Hg to 54.9 +/- 6.1 mm Hg (p = 0.012). It also significantly increased the percent change from mean arterial pressure to EEP from 0.2 +/- 0.3% to 23.3 +/- 6.1% (p = 0.012) and SHE from 133.2 +/- 234.5 erg/cm to 20,219.8 +/- 5842.7 erg/cm3 (p = 0.012). However, no statistical difference was observed between CP and IABP/CP in terms of mean carotid artery pressure (p = NS). In a cardiac-arrested animal model, pulsatility generated by a IABP/CP combination may be effective in terms of energy equivalent pressure and surplus hemodynamic energy.
authors.affiliation: Anesthesiology and Pain Medicine, Korea University, Seoul, Korea.
authors.forename: Choon Hak
authors.initials: CH
authors.lastname: Lim
authors.forename: Ho Sung
authors.initials: HS
authors.lastname: Son
authors.forename: Yung Hu
authors.initials: YH
authors.lastname: Fang
authors.forename: Jung Joo
authors.initials: JJ
authors.lastname: Lee
authors.forename: Kwang Je
authors.initials: KJ
authors.lastname: Baik
authors.forename: Kyung Hyun
authors.initials: KH
authors.lastname: Kim
authors.forename: Bum Soo
authors.initials: BS
authors.lastname: Kim
authors.forename: Hye Won
authors.initials: HW
authors.lastname: Lee
authors.forename: Kyung
authors.initials: K
authors.lastname: Sun
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization / Q000379:methods; D002320:Cardiovascular Physiological Phenomena; D006353:Heart-Assist Devices; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D013552:Swine