Therapeutic tricyclic antidepressant drug monitoring in younger and older depressive patients.
The present study shows the evaluation of clinical state and serum level of tricyclic antidepressants in thirty-eight depressive younger and elderly patients during 8-week observation. We observed no statistically significant differences, neither in psychometric scale scores nor in drug serum levels in both groups of patients.
Radziwoń-Zaleska
Maria
M
Department of Psychiatry, Medical University of Warsaw, Nowowiejska 27, PL 00-665 Warszawa, Poland. maria.radziwon@psych.waw.pl
Matsumoto
Halina
H
Skalski
Michał
M
Wilkowska
Joanna
J
Januszko
Piotr
P
Matoszko
Daria
D
Dziklińska
Anna
A
Gmaj
Bartłomiej
B
Szelenberger
Waldemar
W
D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use; D003863:Depression / Q000097:blood / Q000188:drug therapy*; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D013997:Time Factors; D016896:Treatment Outcome
D000929:Antidepressive Agents, Tricyclic; D002997:Clomipramine; D007099:Imipramine