title: [Giant condyloma with malignant degeneration: a case report].
abstract: We report a case of giant condyloma with malignant degeneration. A 56-year-old male was referred to our hospital due to a penile infection that was resistant to antibiotic therapy for more than a year. The swelling appeared to be a penile cancer. We suspected malignancy and performed penile biopsies twice; however, the histopathological diagnosis was condyloma acuminatum and malignant findings were absent. We continued the antibiotic therapy for 3 months; however, no improvement was achieved. Therefore, total penectomy and urinary diversion were performed. The pathological diagnosis of the resected tissues was not only condyloma but also squamous cell carcinoma, and cancer cells appeared on the cut surface of the specimens. We added radiation therapy. There was no evidence of recurrence or metastasis at 18 months after surgery.
authors.affiliation: The Department of Urology, Komaki City Hospital.
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Funahashi
authors.forename: Osamu
authors.initials: O
authors.lastname: Kamihira
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Fukatsu
authors.forename: Kyousuke
authors.initials: K
authors.lastname: Kimura
authors.forename: Naoto
authors.initials: N
authors.lastname: Sassa
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsuura
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D003218:Condylomata Acuminata / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000209:etiology* / Q000473:pathology