No association between synapsin III gene promoter polymorphisms and multiple sclerosis in German patients.
We investigated whether the polymorphisms rs133946 and rs133945 in the promoter region of the synapsin III (SYN3) gene are associated with multiple sclerosis in German patients. Association of the SYN3 variations and haplotypes with MS is not evident in German MS patients - in contrast to a MS cohort from Italy, as reported previously.
Akkad
Denis A
DA
Gödde
René
R
Epplen
Jörg T
JT
D000483:Alleles; D005787:Gene Frequency; D005838:Genotype; D005858:Germany / Q000453:epidemiology; D006801:Humans; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D016704:Synapsins / Q000235:genetics*
D016704:Synapsins