Chemotherapy-induced neuropathy.
Increasingly, surgeons are becoming aware of the successful treatment of symptomatic peripheral neuropathy by surgical decompression of peripheral nerves. Armed with the knowledge that patients can have underlying neuropathy with overlying anatomic compressions, surgeons have affected improvement in diabetes-induced neuropathy, neuropathy of unknown etiology, and chemotherapy-induced neuropathy. This article details the most well-known culprits in chemotherapy-induced neuropathy and discusses the putative mechanisms of action, medical management, and surgical data.
Rosson
Gedge D
GD
Division of Plastic Surgery, JHOC 8th Floor, McElderry 8152-A, 601 North Caroline Street, Baltimore, MD 21287, USA. gedge@jhmi.edu
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D019299:Decompression, Surgical; D006801:Humans; D009408:Nerve Compression Syndromes / Q000139:chemically induced / Q000601:surgery; D010525:Peripheral Nerves / Q000601:surgery; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000601:surgery; D051381:Rats
D000970:Antineoplastic Agents