title: [MRI-guided biopsy of suspicious abnormalities in the breast].
abstract: In a 55-year-old woman, an echographically occult breast tumour was only visible in one direction on mammography. MRI-guided needle localisation of the lesion followed by surgical excision biopsy were then carried out for diagnostic purposes. In a second woman, 61 years of age, mammographic needle localisation of a deep, echographically occult, lesion was unsuccessful. She then also underwent MRI-guided needle localisation followed by surgical excision biopsy. A third woman, also 61 years of age, with known carcinoma underwent an MRI staging study. This revealed a second, mammographically and echographically occult, lesion for which MRI-guided large-core needle biopsy was done. MRI of the breast has a high sensitivity for the detection of invasive breast carcinoma. MRI of the breast reveals suspicious lesions that cannot be seen on the conventional mammogram or by echography in 15-25% of the cases. In order to obtain tissue from these lesions for histopathology, MRI-guided biopsy techniques have been developed. The most commonly used methods are MRI-guided needle localisation followed by surgical excision biopsy and MRI-guided large-core needle biopsy. The demand for MRI-guided breast interventions is growing because of the increasing use of MRI of the breast in clinical practice.
authors.affiliation: Afd. Radiologie, Universitair Medisch Centrum Utrecht, Heidelberglaan 100, 3584 CX Utrecht.
authors.forename: C
authors.initials: C
authors.lastname: Meeuwis
authors.forename: M A A J
authors.initials: MA
authors.lastname: van den Bosch
authors.forename: K A F
authors.initials: KA
authors.lastname: Houwert
authors.forename: A M
authors.initials: AM
authors.lastname: Fernandez-Gallardo
authors.forename: R
authors.initials: R
authors.lastname: van Hillegersberg
authors.forename: W P Th M
authors.initials: WP
authors.lastname: Mali
mesh_terms: D044963:Biopsy, Fine-Needle / Q000295:instrumentation* / Q000379:methods*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D009367:Neoplasm Staging