[Effect of combined therapy of modified kangjia recipe combined with western medicine on hyperthyroidism].
OBJECTIVE
To observe the therapeutic effect of combined therapy of modified Kangjia Recipe (KR) and western medicine propylthiouracil (PTU) on hyperthyroidism and to assess its advantage.


METHODS
Ninety patients with hyperthyroidism were divided into the treatment group (TG) and the control group (CG). The 60 patients in TG treated with KR and PTU, and the 30 patients in CG treated with PTU alone. The treatment course of both groups was 3 months. The serum thyroid hormone (TH) level, clinical symptoms and signs, and adverse reaction were observed before and after treatment.


RESULTS
The serum TH level, clinical symptoms and signs were significantly improved after treatment in both groups (all P < 0.01). The total effective rate was 93.3% in TG, which was higher than that in CG (83.3%, P < 0.01); and the efficacy in improving palpitation, fidget, aversion to heat, sweating and insomnia was better in the TG than that in the CG respectively (P < 0.05). As for the incidence of adverse reaction, it that was lower in the TG than in the CG.


CONCLUSIONS
KD has good efficacy in treating hyperthyroidism, and the combined treatment of Chinese and Western medicine shows obvious advantages.
Zheng
Min
M
Department of Endocrinology, Yueyang Hospital of Integrative Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437.
Yang
Hong-jie
HJ
Fan
Jun
J
D000328:Adult; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011441:Propylthiouracil / Q000008:administration & dosage*
D004365:Drugs, Chinese Herbal; D011441:Propylthiouracil