title: Guaianolides from Salvia nubicola (Lamiaceae).
abstract: A new sesquiterpene-lactone (nubenolide) belonging to the guaianolide class along with its acetate (nubenolide acetate) and a dimer (bisnubenolide) have been isolated from Salvia nubicola collected from Quetta, Pakistan. Structures of all three new metabolites were elucidated with the aid of spectroscopic techniques including 2D-NMR. However, the structure of nubenolide was finally confirmed via single-crystal X-ray diffraction method.
authors.affiliation: H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan. shaiq303@hotmail.com
authors.forename: Muhammad Shaiq
authors.initials: MS
authors.lastname: Ali
authors.forename: Waqar
authors.initials: W
authors.lastname: Ahmed
authors.forename: Andrea Florence
authors.initials: AF
authors.lastname: Armstrong
authors.forename: Syed Amir
authors.initials: SA
authors.lastname: Ibrahim
authors.forename: Shakeel
authors.initials: S
authors.lastname: Ahmed
authors.forename: Masood
authors.initials: M
authors.lastname: Parvez
mesh_terms: D003508:Cycloheptanes / Q000737:chemistry* / Q000145:classification / Q000302:isolation & purification; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D008968:Molecular Conformation; D027544:Salvia / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D045789:Sesquiterpenes, Guaiane / Q000737:chemistry* / Q000145:classification / Q000302:isolation & purification; D013045:Species Specificity; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D003508:Cycloheptanes; D007783:Lactones; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C514028:bisnubenolide; C421026:guaiane; C514027:nubenolide