title: Dark immunofluorescence: correlation with serum immunoglobulin abnormalities.
abstract: Occasional serum samples (<0.5%) tested by indirect immunofluorescence showed less fluorescence than did negative-control serum. A retrospective review of these patients' serum immunoglobulins revealed a high percentage of abnormalities (71%, versus 22% of controls). We suggest that this observation should be reported when seen and that the clinician should be alerted to an association with immunoglobulin abnormalities.
authors.affiliation: Department of Haematology Immunology Section, Colchester General Hospital, Turner Road, Colchester, Essex CO4 5JL, United Kingdom. jenny.list@essexrivers.nhs.uk
authors.forename: J
authors.initials: J
authors.lastname: List
authors.forename: M S
authors.initials: MS
authors.lastname: Buckland
authors.forename: B
authors.initials: B
authors.lastname: Thobhani
authors.forename: C J
authors.initials: CJ
authors.lastname: Sheed
authors.forename: J C
authors.initials: JC
authors.lastname: Mann
authors.forename: M
authors.initials: M
authors.lastname: Claxton
authors.forename: B
authors.initials: B
authors.lastname: Heelan
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002460:Cell Line; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D000882:Haplorhini; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012377:Rodentia; D013194:Staining and Labeling
chemical_list: D007136:Immunoglobulins