A new streptomycete producing diphenyl sulfone antibiotic--S. sulfonensis.
About 359 actinomycetes were isolated from 8 different natural substrates collected from different parts of Andhra Pradesh. The isolates were screened on the basis of their inhibitory effect against test organisms. Finally one potent antibiotic producer was chosen having broad-spectrum activity against Gram-positive and Gram-negative bacteria and it was found to produce a diphenyl sulfone antibiotic. On the basis of morphological, cultural, physiological and biochemical characters, the diphenyl sulfone antibiotic producer was identified as a new species and was designated as S. sulfonensis.
Ellaiah
P
P
Pharmaceutical Biotechnology Division, Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530 003, India.
Rao
V S
VS
Rao
B V
BV
Srinivasulu
B
B
Ghani
T A
TA
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D002473:Cell Wall / Q000737:chemistry; D012965:Sodium Chloride / Q000494:pharmacology; D013302:Streptomyces / Q000378:metabolism*; D013450:Sulfones / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D013450:Sulfones; D012965:Sodium Chloride