title: Coexistence of psoriasis and pemphigoid--only a coincidence?
abstract: It has previously been reported that pemphigoid coexists with psoriasis more frequently than it could be predicted on the basis of random distribution in the general population. In this study we present three psoriatic patients who developed tense blisters, which most likely were not provoked by anti-psoriatic treatment. Diagnosis of bullous pemphigoid in these cases was established by an overlay antigen mapping technique by laser confocal microscopy, immunoblotting and ELISA. In the context of these cases and the literature, we also discuss possible reasons for the coexistence of psoriasis and pemphigoid as well as selected aspects of diagnosis and therapy of patients simultaneously suffering from these two diseases.
authors.affiliation: Department of Dermatology, Medical University of Warsaw, 02-008 Warsaw, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Lazarczyk
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Wozniak
authors.forename: Norito
authors.initials: N
authors.lastname: Ishii
authors.forename: Anna
authors.initials: A
authors.lastname: Gorkiewicz-Petkov
authors.forename: Takashi
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Robert
authors.initials: R
authors.lastname: Schwarz
authors.forename: Cezary
authors.initials: C
authors.lastname: Kowalewski
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000097:blood; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000276:immunology / Q000473:pathology; D011565:Psoriasis / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D001323:Autoantibodies