Multishot diffusion-weighted PROPELLER magnetic resonance imaging of the abdomen.
OBJECTIVE
The objective of this study was to evaluate the feasibility of using multishot PROPELLER for diffusion-weighted imaging (DWI) of the abdomen.


METHODS
Diffusion-weighted abdominal imaging was performed in 9 healthy volunteers and 3 patients using both single-shot DW-SE-EPI and multishot DW-PROPELLER (BLADE sequence). We compared ADC measurements in phantoms, liver and pancreatic tissues and performed qualitative comparisons of the diffusion-weighted images and ADC maps provided by these 2 techniques.


RESULTS
DW-PROPELLER significantly improved image quality (P < 0.05) with reduced geometric distortion and artifact. The ADC values of phantoms and abdominal organs measured by DW-PROPELLER were generally greater than those measured by single-shot DW-SE-EPI. The ADC values measured by both DWI techniques were significantly different for liver tissues but not for pancreatic tissues (P < 0.05). Preliminary patient studies demonstrated clearly distinguished lesion areas from surrounding normal liver tissues in the DW-PROPELLER images. DW-PROPELLER offers the potential for high-resolution DWI of the abdomen.


CONCLUSIONS
The multishot DW-PROPELLER sequence is a promising technique for DWI of abdominal organs. Future clinical studies will evaluate the use of DW-PROPELLER technique for abdominal oncologic imaging applications.
Deng
Jie
J
Department of Radiology, Northwestern University, Chicago, Illinois 60611, USA.
Miller
Frank H
FH
Salem
Riad
R
Omary
Reed A
RA
Larson
Andrew C
AC
D000005:Abdomen / Q000473:pathology*; D000465:Algorithms; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008113:Liver Neoplasms / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity