title: Symmetry breaking in C. elegans: another gift from the sperm.
abstract: Polarization of the C. elegans embryo depends on the sperm-contributed centrosome, which cues a retraction of the actomyosin cortex to the opposite end of the embryo by an unknown mechanism. New evidence reveals that the sperm donates a second polarizing cue that may locally relax the actomyosin cortex near the point of sperm entry.
authors.affiliation: Biology Department, The University of North Carolina at Chapel Hill, 27599, USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Marston
authors.forename: Bob
authors.initials: B
authors.lastname: Goldstein
mesh_terms: D000205:Actomyosin / Q000378:metabolism*; D000818:Animals; D019521:Body Patterning; D017173:Caenorhabditis elegans / Q000196:embryology* / Q000235:genetics; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism; D018385:Centrosome / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D015398:Signal Transduction; D013094:Spermatozoa / Q000502:physiology*
chemical_list: D029742:Caenorhabditis elegans Proteins; D000205:Actomyosin