title: Parry-Romberg syndrome with a clinically silent white matter lesion.
abstract: We performed a detailed neuroimaging study in a patient with Parry-Romberg syndrome. Proton MR spectroscopy demonstrated normal spectral patterns, though conventional MR imaging revealed high-intensity areas in the entire white matter in the left hemisphere. Single-photon emission tomography showed increased perfusion in the cortex of the affected hemisphere. Pyramidal tracts and optic radiations were preserved on diffusion tensor tractography. We will correlate these neuroimaging findings with normal psychomotor development in our patient.
authors.affiliation: Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan. okumura@med.nagoya-u.ac.jp
authors.forename: A
authors.initials: A
authors.lastname: Okumura
authors.forename: T
authors.initials: T
authors.lastname: Ikuta
authors.forename: T
authors.initials: T
authors.lastname: Tsuji
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: H
authors.initials: H
authors.lastname: Fukatsu
authors.forename: S
authors.initials: S
authors.lastname: Naganawa
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D002540:Cerebral Cortex / Q000473:pathology* / Q000503:physiopathology; D002675:Child, Preschool; D003952:Diagnostic Imaging; D038524:Diffusion Magnetic Resonance Imaging; D004292:Dominance, Cerebral / Q000502:physiology*; D005150:Facial Hemiatrophy / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000473:pathology / Q000502:physiology; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D009460:Neurologic Examination; D011597:Psychomotor Performance / Q000502:physiology; D012016:Reference Values; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed