title: Sub-cutaneous phaeohyphomycosis caused by Cladophialophora devriesii in a United Kingdom resident.
abstract: An 83-year-old diabetic man receiving corticosteroids developed a forearm lesion. Histology confirmed the presence of a dematiaceous fungus, with associated granulomatous inflammation. Culture of a biopsy yielded fungal colonies with branching chains of single-celled, melanised, dry, sympodial conidia, which were identified as Cladophialophora devriesii on the basis of morphology and rDNA gene sequencing. To date, C. devriesii has been a relatively rare cause of human disease. To our knowledge, this is only the second case to be described, and the first report of infection in a UK resident.
authors.affiliation: Regional Mycology Laboratory, Hope Hospital, Manchester, UK. showard@fs1.ho.man.ac.uk
authors.forename: S J
authors.initials: SJ
authors.lastname: Howard
authors.forename: S L
authors.initials: SL
authors.lastname: Walker
authors.forename: S M
authors.initials: SM
authors.lastname: Andrew
authors.forename: A M
authors.initials: AM
authors.lastname: Borman
authors.forename: E M
authors.initials: EM
authors.lastname: Johnson
authors.forename: D W
authors.initials: DW
authors.lastname: Denning
mesh_terms: D000369:Aged, 80 and over; D001203:Ascomycota / Q000235:genetics / Q000302:isolation & purification*; D004275:DNA, Ribosomal / Q000032:analysis / Q000235:genetics; D003881:Dermatomycoses / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D006113:United Kingdom
chemical_list: D004275:DNA, Ribosomal