title: Prenatal diagnosis of a fibrosarcoma of the thigh: a case report.
abstract: We report a rare case of fibrosarcoma of the thigh suspected prenatally. At 27 weeks of gestation a voluminous, vascularised mass was discovered at ultrasound on the foetus' left leg, suggestive of haemangioma or a fibrosarcoma. There were no signs of heart failure. A rapid increase in the tumour mass was noted and a caesarean section was carried out at 39 weeks because of abnormal foetal heart rate. Postnatal ultrasound examination was comparable to that carried out prenatally; pathological examination of the mass biopsied and immunohistochemical investigation provided a diagnosis of congenital fibrosarcoma. After neoadjuvant chemotherapy and surgery the infant is now in complete remission without amputation.
authors.affiliation: Service de Gynécologie-Obstétrique et de Médecine de la Reproduction, Caen, France. luc.durin@libertysurf.fr
authors.forename: Luc
authors.initials: L
authors.lastname: Durin
authors.forename: Corinne
authors.initials: C
authors.lastname: Jeanne-Pasquier
authors.forename: Patrick
authors.initials: P
authors.lastname: Bailleul
authors.forename: Cyril
authors.initials: C
authors.lastname: Eboué
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Aicardi
authors.forename: Michel
authors.initials: M
authors.lastname: Herlicoviez
authors.forename: Michel
authors.initials: M
authors.lastname: Dreyfus
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D013848:Thigh; D016216:Ultrasonography, Prenatal