title: In vitro prostate cancer cell growth inhibition by Brazilian plant extracts.
abstract: In the present study, 1220 plant extracts obtained from 352 plants belonging to 73 families that grow in the Amazon and Atlantic rain forests were screened for cytotoxicity against PC-3 prostate cancer cell lines. Extracts were tested in the single dose of 100 microg/mL. Activity was observed in 17 aqueous or organic extracts belonging to Annonaceae, Apocynaceae, Araceae, Capparaceae, Commelinaceae, Flacourtiaceae, Lecythidaceae, Leguminosae, Passifloraceae, Rutaceae, and Violaceae.
authors.affiliation: Laboratório de Extração, Universidade Paulista, São Paulo, SP, Brazil. extractlab@unip.br
authors.forename: I B
authors.initials: IB
authors.lastname: Suffredini
authors.forename: M L B
authors.initials: ML
authors.lastname: Paciencia
authors.forename: A D
authors.initials: AD
authors.lastname: Varella
authors.forename: R N
authors.initials: RN
authors.lastname: Younes
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001938:Brazil; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D011471:Prostatic Neoplasms / Q000188:drug therapy*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts