title: A chemical reporter strategy to probe glycoprotein fucosylation.
abstract: Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California, USA.
authors.forename: David
authors.initials: D
authors.lastname: Rabuka
authors.forename: Sarah C
authors.initials: SC
authors.lastname: Hubbard
authors.forename: Scott T
authors.initials: ST
authors.lastname: Laughlin
authors.forename: Sulabha P
authors.initials: SP
authors.lastname: Argade
authors.forename: Carolyn R
authors.initials: CR
authors.lastname: Bertozzi
mesh_terms: D001386:Azides / Q000737:chemistry / Q000378:metabolism; D005434:Flow Cytometry; D005643:Fucose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*; D006023:Glycoproteins / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D019169:Jurkat Cells; D008958:Models, Molecular; D011134:Polysaccharides / Q000737:chemistry / Q000378:metabolism
chemical_list: D001386:Azides; D006023:Glycoproteins; D011134:Polysaccharides; D005643:Fucose