title: Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077 Göttingen, Germany. ltietze@gwdg.de
authors.forename: Lutz F
authors.initials: LF
authors.lastname: Tietze
authors.forename: Birgit
authors.initials: B
authors.lastname: Krewer
authors.forename: Holm
authors.initials: H
authors.lastname: Frauendorf
authors.forename: Felix
authors.initials: F
authors.lastname: Major
authors.forename: Ingrid
authors.initials: I
authors.lastname: Schuberth
mesh_terms: D000477:Alkylating Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D053938:DNA Fragmentation; D000080890:Duocarmycins; D004591:Electrophoresis, Polyacrylamide Gel; D007202:Indicators and Reagents; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011355:Prodrugs / Q000138:chemical synthesis; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000477:Alkylating Agents; D000080890:Duocarmycins; D007202:Indicators and Reagents; D007211:Indoles; D011355:Prodrugs; D011758:Pyrroles; C066098:duocarmycin SA; D004247:DNA