title: Investigation of surface interactions in molecular recognition of phosphonate imprinted organosilicates and the role of water.
abstract: Surface interactions in molecular recognition of phosphonate imprinted organosilicates and the role of water have been studied. NMR and calorimetry studies have shown the changing nature of the surface water structure on silicate surfaces due to template directed molecular imprinting. Results indicate the interaction of an organophosphonate compound with the functionalized silica surfaces to be through surrounding water molecules. However, with nonfunctionalized surfaces, additional higher energy interactions were possible. Further, our results support the possible templating effect of water during the imprint process.
authors.affiliation: Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington, D.C. 20375, USA.
authors.forename: Shalini
authors.initials: S
authors.lastname: Jayasundera
authors.forename: Mazyar
authors.initials: M
authors.lastname: Zeinali
authors.forename: Joel B
authors.initials: JB
authors.lastname: Miller
authors.forename: Luminita M
authors.initials: LM
authors.lastname: Velea
authors.forename: Bruce P
authors.initials: BP
authors.lastname: Gaber
authors.forename: Michael A
authors.initials: MA
authors.lastname: Markowitz
mesh_terms: D000327:Adsorption; D002151:Calorimetry; D002627:Chemistry, Physical / Q000379:methods*; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D063065:Organophosphonates / Q000737:chemistry*; D011108:Polymers; D017640:Silicates / Q000737:chemistry*; D012822:Silicon Dioxide; D013499:Surface Properties; D013696:Temperature; D014867:Water / Q000737:chemistry*
chemical_list: D063065:Organophosphonates; D011108:Polymers; D017640:Silicates; D014867:Water; D012822:Silicon Dioxide