[Idiopathic tumoral calcinosis: two cases and review of the literature].
Two black patients from Africa presented idiopathic tumoral calcinosis. This rare disease, defined by the presence of calcified deposits in peri-articular tissues remains poorly elucidated. Pathogenesis is still hypothetical. The diagnosis can be established with careful physical examination and appropriate complementary exams, allowing early complete surgical resection without biopsy. Pathology examination is required for formal differential diagnosis. The present tumors were particularly large, but did not produce signs of compression. In the first patient, the tumor developed after pregnancy in the zone of antibiotic injections. The second patient presented multiple bilateral symmetrical localizations with bone invasion. Histology confirmed the nature of the lesions and revealed bony metaplasie in the first patient, an element rarely described. Prognosis is excellent with early treatment. Recurrence is the rule in the event of incomplete resection. We discuss the appropriate diagnostic and therapeutic management.
Mathieu
G
G
Service d'Orthopédie et de Traumatologie, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75475 Paris Cedex 10. ghmat@wanadoo.fr
Lemonne
F
F
Flouzat-Lachaniette
C H
CH
Sedel
L
L
D000328:Adult; D002114:Calcinosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006621:Hip Joint; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D010489:Periarthritis / Q000175:diagnosis; D011379:Prognosis; D013997:Time Factors; D014057:Tomography, X-Ray Computed