[Study on real-time control of extraction procedure of Furitus gardenia by near infrared spectroscopy].
A new approach to the real-time control of extraction procedures based on fiber optic near infrared spectroscopy (NIR) was described. Various extraction samples of gardenia were rapidly scanned by NIR, and the SIMCA monitoring model was developed. The model was applied to evaluate the extraction procedures of 26 unknown samples, and all the samples from abnormal procedures were successfully identified. It is suggested that near infrared spectroscopy, combined with SIMCA method, is a rapid, convenient and efficient tool for real-time procedure monitoring, which needs no quantitative determination and can effectively monitor whether the current procedure is in normal or not. The presented approach, therefore, offers a new way for the quality control in real-time of traditional Chinese medicine.
Yan
Shi-kai
SK
Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Luo
Guo-an
GA
Wang
Yi-ming
YM
Cheng
Yi-yu
YY
D005591:Chemical Fractionation / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D032062:Gardenia / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared
D004365:Drugs, Chinese Herbal