title: Kilovoltage CT using a linac-CT scanner combination.
abstract: Modern radiotherapy techniques such as intensity modulation are capable of generating complex dose distributions whose high dose areas tightly conform to the tumour target volume, sparing critical organs even when they are located in close proximity. This potential can only be exploited to its full extent when the accumulated dose actually delivered over the complete treatment course is sufficiently close to the dose computed on the initial CT scan used for treatment planning. Exact patient repositioning is mandatory, but also other sources of error, e.g. changes of the patient's anatomy under therapy, should be taken into account. At the German Cancer Research Center, we use a combination of a linear accelerator and a CT scanner installed in one room and sharing the same couch. It allows the quantification and correction of interfractional variations between planning and treatment delivery. In this paper, we describe treatments of prostate, paraspinal and head and neck tumours. All patients were immobilized by customized fixation devices and treated in a stereotactic setup. For each patient, frequent CT scans were taken during the treatment course. Each scan was compared with the original planning CT using manual checks and automatic rigid matching algorithms. Depending on the individual case, the adaptation to variations was carried out offline after several fractions or in real-time between the CT scan and linac irradiation. We discuss the techniques for detecting and correcting interfractional errors and outline the procedural steps of a linac-CT scanner-supported radiation treatment course.
authors.affiliation: Department of Radiation Oncology, University Hospital of Heidelberg and German Cancer Research Center, Heidelberg.
authors.forename: C
authors.initials: C
authors.lastname: Thieke
authors.forename: U
authors.initials: U
authors.lastname: Malsch
authors.forename: W
authors.initials: W
authors.lastname: Schlegel
authors.forename: J
authors.initials: J
authors.lastname: Debus
authors.forename: P
authors.initials: P
authors.lastname: Huber
authors.forename: R
authors.initials: R
authors.lastname: Bendl
authors.forename: C
authors.initials: C
authors.lastname: Thilmann
mesh_terms: D006801:Humans; D008433:Mathematics; D009369:Neoplasms / Q000532:radiotherapy*; D019047:Phantoms, Imaging; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation / Q000379:methods; D015898:Tomography Scanners, X-Ray Computed; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*