[Effect of sildenafil on nocturnal penile tumescence].
OBJECTIVE
To evaluate the efficacy of sildenafil on nocturnal penile tumescence (NPT).


METHODS
Thirty-five patients with erectile dysfunction (ED), 28 cases of organic ED and 7 cases of psychogenic ED, were treated with sildenafil 100 mg before bedtime. The NPT of the patients was observed by using NEVA.


RESULTS
Erectile function significantly improved in the 28 cases of organic ED (P < 0.05), but not in the 7 cases of psychogenic ED (P > 0.05).


CONCLUSIONS
Sildenafil can improve NPT of organic ED patients without sexual stimulation.
Chen
Zhi-Yong
ZY
Department of Urology, Second Affiliated Hospital, Wenzhou Medical College, Wenzhou, Zhejiang 325027, China. chenzy96@sohu.com
Chen
Ying-He
YH
Zhu
Hai-Bo
HB
He
You-Hua
YH
Zhang
Lei
L
Yang
Shi-Kun
SK
D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010410:Penile Erection / Q000187:drug effects*; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology*; D010879:Piperazines / Q000494:pharmacology*; D011687:Purines / Q000494:pharmacology; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000494:pharmacology*
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate