title: Methicillin-resistant Staphylococcus aureus in children, Taiwan.
abstract: Highly virulent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) is common worldwide. Using antimicrobial drug susceptibility testing, staphylococcal cassette chromosome mec typing, exotoxin profiling, and pulsed-field gel electrophoresis typing, we provide evidence that supports the relationship between nasal strains of PVL-positive MRSA and community-acquired disease.
authors.affiliation: Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheng-Kung Road Section 2, Nei-hu 114, Taipei, Taiwan, Republic of China.
authors.forename: Wen-Tsung
authors.initials: WT
authors.lastname: Lo
authors.forename: Wei-Jen
authors.initials: WJ
authors.lastname: Lin
authors.forename: Min-Hua
authors.initials: MH
authors.lastname: Tseng
authors.forename: Sheng-Ru
authors.initials: SR
authors.lastname: Wang
authors.forename: Mong-Ling
authors.initials: ML
authors.lastname: Chu
authors.forename: Chih-Chien
authors.initials: CC
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001427:Bacterial Toxins / Q000235:genetics / Q000378:metabolism*; D015373:Bacterial Typing Techniques; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D005098:Exotoxins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007956:Leukocidins; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D009296:Nasal Cavity / Q000382:microbiology; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects* / Q000235:genetics; D013624:Taiwan / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin