A prospective study to determine the incidence of atopy in children undergoing adenotonsillectomy for obstructive sleep apnea.
OBJECTIVE
To investigate the relationship between adenotonsillar hypertrophy seen in pediatric obstructive sleep apnea and upper airway allergy to airborne allergens.


METHODS
A prospective study of Radioallergosorbent (RAST) tests to common airborne allergens in children (<16 years old) undergoing adenotonsillectomy for obstructive sleep apnea in a London Teaching Hospital.


RESULTS
20.9% of patients had a positive RAST result to house dust mite, 2.8% to cat hair, 0% to mixed feather, 7.8% to mixed grass pollen and 3.8% to dog hair.


CONCLUSIONS
This study does not support the hypothesis that the adenotonsillar hypertrophy seen in pediatric patients with obstructive sleep apnea is contributed to by allergy to airborne allergens. It is possible that there is a localized allergic reaction in the upper respiratory tract mucosa which is not apparent on an assay of systemic IgE.
Carr
E
E
Department of Ear, Nose & Throat Surgery, Royal Free Hospital, London, United Kingdom. esmond@doctors.org.uk
Obholzer
R
R
Caulfield
H
H
D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology; D000293:Adolescent; D000485:Allergens / Q000276:immunology*; D000818:Animals; D002415:Cats; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000453:epidemiology; D015994:Incidence; D007223:Infant; D008131:London / Q000453:epidemiology; D008297:Male; D008925:Mites / Q000276:immunology; D014066:Palatine Tonsil / Q000473:pathology; D011058:Pollen / Q000276:immunology; D011446:Prospective Studies; D011852:Radioallergosorbent Test; D012130:Respiratory Hypersensitivity / Q000453:epidemiology*; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology / Q000601:surgery*; D014068:Tonsillectomy
D000485:Allergens