Antitumor agents: development of highly potent glycosidic duocarmycin analogues for selective cancer therapy.
Tietze
Lutz F
LF
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077 Göttingen, Germany. ltietze@gwdg.de
Major
Felix
F
Schuberth
Ingrid
I
D000477:Alkylating Agents / Q000138:chemical synthesis* / Q000627:therapeutic use*; D000906:Antibodies / Q000627:therapeutic use; D045744:Cell Line, Tumor; D016503:Drug Delivery Systems; D000080890:Duocarmycins; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*; D011355:Prodrugs / Q000627:therapeutic use; D011758:Pyrroles / Q000138:chemical synthesis / Q000627:therapeutic use; D013302:Streptomyces / Q000737:chemistry; D014410:Tumor Stem Cell Assay
D000477:Alkylating Agents; D000906:Antibodies; D000080890:Duocarmycins; D007211:Indoles; D011355:Prodrugs; D011758:Pyrroles; C066098:duocarmycin SA