title: An unusual case of mediastinal mass due to Fonsecaea pedrosoi.
abstract: Phaeohyphomycosis is a disease caused by dematiaceous fungi. Here, the first culture-proven case of mediastinal mass due to Fonsecaea pedrosoi is reported. The patient was a 40-yr-old male who had presented with history of dyspnoea and dysphagia. Computed tomography of the chest disclosed a mediastinal mass. Cultures of a specimen from the mediastinum grew Fonsecaea pedrosoi. The patient received amphotericin B and itraconazole and showed a remarkable recovery. Repeat computed tomography revealed a reduction in the mediastinal mass. The case highlights the need for a high degree of clinical suspicion and appropriate histopathological and mycological examination of clinical specimens.
authors.affiliation: Dept of Pulmonary Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India. navneetchd@yahoo.com
authors.forename: N
authors.initials: N
authors.lastname: Singh
authors.forename: R
authors.initials: R
authors.lastname: Agarwal
authors.forename: D
authors.initials: D
authors.lastname: Gupta
authors.forename: M R
authors.initials: MR
authors.lastname: Shivaprakash
authors.forename: A
authors.initials: A
authors.lastname: Chakrabarti
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology*; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D009181:Mycoses / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B