title: Lower extremity arterial thrombosis following sonographically guided thrombin injection of a femoral pseudoaneurysm.
abstract: Sonographically guided percutaneous thrombin injection is a minimally invasive and highly successful treatment of arterial pseudoaneurysms. Despite a very low complication rate, several severe arterial thrombotic events have been reported following thrombin injection of pseudoaneurysms. Native arterial thrombosis, though recognized as a severe complication of thrombin injection, has not been well described in the literature. We report a case of successful surgical management of arterial thrombosis after percutaneous thrombin injection of a femoral artery pseudoaneurysm in a 69-year-old woman. The pathophysiology, risk factors, diagnosis, and treatment options for this complication are discussed.
authors.affiliation: Department of Surgery, St. Luke's Hospital and Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA.
authors.forename: Stanislaw P
authors.initials: SP
authors.lastname: Stawicki
authors.forename: Brian A
authors.initials: BA
authors.lastname: Hoey
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000188:drug therapy; D003029:Coagulants / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007267:Injections; D007866:Leg / Q000098:blood supply*; D013917:Thrombin / Q000008:administration & dosage / Q000009:adverse effects*; D013927:Thrombosis / Q000139:chemically induced*; D018084:Ultrasonography, Interventional
chemical_list: D003029:Coagulants; D013917:Thrombin