title: A brief review on software developments for group sequential and adaptive designs.
abstract: In this paper the currently available software we know for group sequential and adaptive designs is briefly reviewed. Stand-alone packages as well as modules within software packages or programming languages exist. New software developments for adaptive designs enable the user to perform data dependent design adaptations while controlling the Type I error rate.
authors.affiliation: Institute for Medical Statistics, Informatics, and Epidemiology, University of Cologne, Joseph-Stelzmann-Str. 9, 50931 Cologne, Germany. gernot.wassmer@uni-koeln.de
authors.forename: Gernot
authors.initials: G
authors.lastname: Wassmer
authors.forename: Marc
authors.initials: M
authors.lastname: Vandemeulebroecke
mesh_terms: D001699:Biometry; D003627:Data Interpretation, Statistical; D015233:Models, Statistical; D012107:Research Design / Q000706:statistics & numerical data*; D018401:Sample Size; D012985:Software Design