title: Synthesis of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions.
abstract: Two types of quinoline scaffolds were constructed in a combinatorial format via the Ugi four-component reaction (U-4CR) and Pd-catalyzed intramolecular arylation reaction. The scope of this two-step synthetic sequence was examined from commercially available and synthetically accessible starting materials.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing, China 100871.
authors.forename: Zhibo
authors.initials: Z
authors.lastname: Ma
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xiang
authors.forename: Tuoping
authors.initials: T
authors.lastname: Luo
authors.forename: Kui
authors.initials: K
authors.lastname: Lu
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Xu
authors.forename: Jiahua
authors.initials: J
authors.lastname: Chen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D011804:Quinolines; D010165:Palladium