title: Management of goblet cell carcinoid.
abstract: OBJECTIVE
  Goblet cell carcinoid, a rare tumor of intermediate malignant potential, is known to account for a significant minority of appendiceal neoplasms. Sixteen new cases of gastrointestinal goblet cell carcinoid were reviewed to describe their presentation, treatment, and outcome.
  
  
  METHODS
  A review of 16 cases from a single institution.
  
  
  RESULTS
  Sixteen patients were diagnosed with goblet cell carcinoid between 1995 and 2005. Presenting diagnoses included appendicitis (n=8), abdominal or liver mass (n=5), uterine fibroids (n=1), ovarian mass (n=1), and Crohn's Disease exacerbation (n=1). Mean follow-up was 12 months with a mortality of 19% (n=3). Patients were divided into two groups: those where the diagnosis was an incidental finding at operation (Group 1) and those where the presentation was of an abdominal mass or metastatic disease (Group 2). Nine of ten patients in Group 1 initially received appendectomies. Group 2 included patients presenting with Krukenberg type lesions (n=2) and abdominal masses (n=4).
  
  
  CONCLUSIONS
  Goblet cell carcinoid is a rare malignant tumor largely affecting the appendix. In patients presenting with appendicitis, our series does not support the recommendation of right hemicolectomy based on pathologic diagnosis alone and surgical intervention must be customized to the individual patient.
authors.affiliation: Department of Surgery, Mount Sinai School of Medicine, New York, New York 10029, USA.
authors.forename: John C
authors.initials: JC
authors.lastname: Byrn
authors.forename: Ju-Lin
authors.initials: JL
authors.lastname: Wang
authors.forename: Celia M
authors.initials: CM
authors.lastname: Divino
authors.forename: Scott Q
authors.initials: SQ
authors.lastname: Nguyen
authors.forename: Richard R P
authors.initials: RR
authors.lastname: Warner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001062:Appendectomy; D001063:Appendiceal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D001064:Appendicitis / Q000150:complications / Q000601:surgery; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D003082:Colectomy; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D006801:Humans; D033162:Incidental Findings; D008113:Liver Neoplasms / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000175:diagnosis