title: [Acute toxoplasmic perimyocarditis in a 67-year-old HIV-negative woman--a case report].
abstract: Acquired toxoplasmosis is a widespread parasitic disease caused by an obligate intracellular protozoan, Toxoplasma gondii. Humans are infected by consuming undercooked or raw meat containing tissue cysts or by ingesting oocysts in food or water contaminated with feline faeces. Most cases of Toxoplasma gondii infections in immunocompetent individuals are asymptomatic. Although acquired toxoplasmosis is usually a mild infection, it may be life-threatening in immunocompromised patients. In this report we present a 67-year-old HIV-negative woman with acute toxoplasmic perimyocarditis, heart failure and with a history of ischemic heart disease, hypertension and dyslipidemia. The diagnosis was based on clinical characteristics, echocardiographic examinations, elevated inflammatory markers and the presence of IgM and IgG antibodies against Toxoplasma gondii. We conclude that Toxoplasma gondii infection should be considered in each case of perimyocarditis with concomitant, significant diagnostic and therapeutic problems, especially in immunocompromised patients. This paper also reviews differential diagnosis of elevated CA 125 serum levels in postmenopausal women.
authors.affiliation: Klinika Choroby Wieńcowej, Instytutu Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
authors.forename: Danuta
authors.initials: D
authors.lastname: Mroczek-Czernecka
authors.forename: Paweł
authors.initials: P
authors.lastname: Rostoff
authors.forename: Wiesława
authors.initials: W
authors.lastname: Piwowarska
mesh_terms: D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D015415:Biomarkers / Q000097:blood; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D006973:Hypertension / Q000150:complications; D016867:Immunocompromised Host; D017202:Myocardial Ischemia / Q000150:complications; D009205:Myocarditis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014123:Toxoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy
chemical_list: D000913:Antibodies, Protozoan; D015415:Biomarkers