MicroRNA protocols. Perspectives.
The discoveries of microRNAs (miRNAs), a class of noncoding RNAs that can regulate gene expression by translational repression, have opened a new avenue on gene modulation in mammalian cells. Conceivably, this highly effective method of modulation of gene expression would be exploited for numerous prospectives, including human, therapeutics. This chapter offers some perspective, with emphasis on areas that can be further developed.
Ying
Shao-Yao
SY
Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Chang
Donald C
DC
Miller
Joseph D
JD
Lin
Shi-Lung
SL
D000818:Animals; D005544:Forecasting; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000502:physiology*; D012106:Research
D035683:MicroRNAs