[Pharmacological treatment of vascular cognitive impairment].
Vascular dementia is second most common cause of dementia. The paper highlights the most important trends in pharmacological treatment of vascular dementia. Result of a clinical trial of some agents appears to be promising. Pentoxifyline appears to be useful in multi-infarct vascular dementia. Nimodipine produced improvement in subcortical dementia. Some other agents like ginkgo biloba, acetylocholinesterase inhibitors, memantine and other also have shown mild benefit or at least were associated with some stabilization of dementia.
Bidzan
Leszek
L
Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego Akademii Medycznej w Gdańsku. kpsych@amg.gda.pl
D000818:Animals; D002561:Cerebrovascular Disorders / Q000188:drug therapy; D003072:Cognition Disorders / Q000188:drug therapy*; D015161:Dementia, Multi-Infarct / Q000188:drug therapy; D015140:Dementia, Vascular / Q000188:drug therapy*; D020441:Ginkgo biloba / Q000187:drug effects; D006801:Humans; D009553:Nimodipine / Q000627:therapeutic use*; D018697:Nootropic Agents / Q000627:therapeutic use*; D048448:Phenylcarbamates / Q000627:therapeutic use*; D014652:Vascular Diseases / Q000188:drug therapy*
D018697:Nootropic Agents; D048448:Phenylcarbamates; D009553:Nimodipine