Electrochemical sensing DNA damage with nano-titanium dioxide and repair with a medicinal herb species resveratrol.
We have developed a simple electrochemical method to detect DNA damage caused by the photovoltaic effect of nano-TiO(2). Meanwhile, we have found that resveratrol, a Chinese Traditional Medicinal Herb species, can have a repairing effect to the oxidized DNA, which can also be detected with the proposed technique in this paper.
Chen
Guifang
G
Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
Zhao
Jing
J
Liu
Xinjian
X
Gao
Ge
G
Huang
Junyi
J
Li
Genxi
G
D000975:Antioxidants / Q000737:chemistry; D015374:Biosensing Techniques / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D004249:DNA Damage; D004260:DNA Repair; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D004563:Electrochemistry; D015394:Molecular Structure; D036103:Nanotechnology; D017382:Reactive Oxygen Species / Q000737:chemistry; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry* / Q000528:radiation effects
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D017382:Reactive Oxygen Species; D013267:Stilbenes; C009495:titanium dioxide; D014025:Titanium; D000077185:Resveratrol