title: In-vivo effects of fluoridated antiplaque dentifrice and bonding material on enamel demineralization adjacent to orthodontic appliances.
abstract: BACKGROUND
  The effect of a fluoridated antiplaque dentifrice on the development of caries lesions adjacent to dental appliances bonded with ionomeric material is unknown.
  
  
  METHODS
  Fourteen orthodontic patients were randomly divided into 2 groups of 7. One group brushed 3 times a day with a fluoridated dentifrice, and the other used an experimental antiplaque fluoridated formulation. Bracket bases were randomly bonded with either resin-modified glass ionomer cement or composite resin to the buccal surfaces of either the maxillary left or right premolars in each subject. The teeth were banded, leaving a space on the buccal surface to allow dental plaque accumulation. After 28 days of dentifrice use, the teeth were extracted, and mineral loss in the enamel adjacent to the bonded material was assessed by cross-sectional microhardness.
  
  
  RESULTS
  Mineral loss in the enamel surrounding the bond with the resin-modified glass ionomer cement was lower (P <.05) than around the composite bond. Enamel demineralization was lower (P <.05) in subjects who used the experimental antiplaque fluoridated formulation than in those who used the fluoridated one.
  
  
  CONCLUSIONS
  The data suggest that an antiplaque fluoridated dentifrice is superior to one that is only fluoridated for reducing enamel demineralization adjacent to dental material bonded with composite, but the effect seems irrelevant when bonding is done with the ionomeric material.
authors.affiliation: Department of Pathology and Clinical Dentistry, Federal University of Piauí, Teresina, PI, Brazil. alexcoeli@uol.com.br
authors.forename: Marcoeli Silva
authors.initials: MS
authors.lastname: de Moura
authors.forename: Alexandre Henrique
authors.initials: AH
authors.lastname: de Melo Simplício
authors.forename: Jaime Aparecido
authors.initials: JA
authors.lastname: Cury
mesh_terms: D000180:Acrylic Resins; D000293:Adolescent; D000538:Aluminum Silicates; D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage; D017438:Bisphenol A-Glycidyl Methacrylate; D002327:Cariostatic Agents / Q000008:administration & dosage; D002648:Child; D001840:Dental Bonding / Q000379:methods*; D003773:Dental Plaque / Q000517:prevention & control*; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D011756:Diphosphates / Q000008:administration & dosage; D004338:Drug Combinations; D005899:Glass Ionomer Cements; D006244:Hardness; D006801:Humans; D008298:Maleates / Q000008:administration & dosage; D016910:Orthodontic Brackets / Q000009:adverse effects*; D011145:Polyvinyls / Q000008:administration & dosage; D019279:Resin Cements; D016037:Single-Blind Method; D012969:Sodium Fluoride / Q000008:administration & dosage; D017001:Tooth Demineralization / Q000209:etiology / Q000517:prevention & control*; D014260:Triclosan / Q000008:administration & dosage; D017967:Zinc Compounds / Q000008:administration & dosage
chemical_list: D000180:Acrylic Resins; D000538:Aluminum Silicates; D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D003802:Dentifrices; D011756:Diphosphates; D004338:Drug Combinations; C095451:Fuji Ortho LC; D005899:Glass Ionomer Cements; D008298:Maleates; D011145:Polyvinyls; D019279:Resin Cements; D017967:Zinc Compounds; C058026:polyvinylmethoxyethylene-maleic anhydride copolymer; D017438:Bisphenol A-Glycidyl Methacrylate; D014260:Triclosan; D012969:Sodium Fluoride