title: Curative resection for low rectal adenocarcinoma: abdomino-perineal vs anterior resection.
abstract: OBJECTIVE
  Local recurrence after abdomino-perineal excision of the rectum for tumours has been reported to occur in up to a third of patients in contrast to 4% after restorative anterior resection.
  
  
  METHODS
  Low rectal tumours were defined as tumours within 8 cm of the anal verge and were treated by either stapled low anterior resection (SLAR) or abdomino-perineal excision of the rectum (APER). One hundred and seventy-eight patients with tumours in the lower third of the rectum (30% of 591 rectal cancers) underwent surgical resection between 1980 and 2001. Data were collected prospectively; 68 (38%) had SLAR and 110 (62%) had APER with median follow up of approximately 12 years; 54 SLAR (79%) and 76 APER (69%) had curative procedures on clinical and pathological criteria.
  
  
  RESULTS
  Local and distant recurrence occurred in seven (13%) and eight (15%) patients in the SLAR group and six (8%) and 14 (18%) patients in the APER group, respectively. Overall 5-year survival was 63% and 60% in the SLAR and APER groups, respectively
  
  
  CONCLUSIONS
  For rectal cancers within 8 cm of the anal verge, both procedures achieved equivalent results measured by low local recurrence rates and overall survival.
authors.affiliation: Colorectal Unit, Royal Surrey County Hospital, Guildford, Surrey, UK.
authors.forename: A C
authors.initials: AC
authors.lastname: Okaro
authors.forename: T
authors.initials: T
authors.lastname: Worthington
authors.forename: J F
authors.initials: JF
authors.lastname: Stebbing
authors.forename: M
authors.initials: M
authors.lastname: Broughton
authors.forename: S
authors.initials: S
authors.lastname: Caffarey
authors.forename: C G
authors.initials: CG
authors.lastname: Marks
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D013505:Digestive System Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome