Metastatic atypical choroid plexus papilloma: a case report.
Choroid plexus papillomas (CPPs) are rare adult tumours and metastatic disease is even less common, more typically associated with choroid plexus carcinoma. We present the case of a 32-year-old patient with multiple metastases arising along the length of the neuraxis 3 years after resection of an atypical fourth ventricular CPP. Metastatic deposits were found from the mid-brain to the lumbar cistern and the patient underwent repeat excision of the fourth ventricular tumour, partial resection of a cervico-thoracic deposit and craniospinal radiotherapy. Possible explanations for the rarity of atypical CPP include unclear diagnostic criteria leading to under-representation in reported cases. We review the current literature on metastatic CPP and discuss the role of surgery and adjuvant therapy in relation to both typical and atypical disease.
Uff
Christopher E G
CE
Department of Neurosurgery, Royal Free Hospital, Hampstead, London, UK. chrisuff@hotmail.com
Galloway
Malcolm
M
Bradford
Robert
R
D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D020546:Fourth Ventricle / Q000473:pathology; D005910:Glioma / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D020288:Papilloma, Choroid Plexus / Q000473:pathology* / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000556:secondary* / Q000601:surgery