title: Exclusive intrapulmonary lepidic growth of a malignant pleural mesothelioma presenting with pneumothorax and involving the peritoneum.
abstract: We report a rare case of malignant pleural mesothelioma presenting clinically with pneumothorax and histologically with an exclusive intrapulmonary lepidic growth. Neither intrathoracic nodules nor pleural thickening were found. The patient subsequently experienced acute abdominal pain with peritonitis and intestinal occlusion by peritoneal mesothelioma. The morphologic clues leading to the correct diagnosis of mesothelioma with prominent intrapulmonary growth are briefly discussed.
authors.affiliation: Section of Pathologic Anatomy, Azienda Policlinico, Modena, Italy. rossi.giulio@policlinico.mo.it
authors.forename: Giulio
authors.initials: G
authors.lastname: Rossi
authors.forename: Alberto
authors.initials: A
authors.lastname: Cavazza
authors.forename: Ercole
authors.initials: E
authors.lastname: Turrini
authors.forename: Matteo
authors.initials: M
authors.lastname: Costantini
authors.forename: Christian
authors.initials: C
authors.lastname: Casali
authors.forename: Uliano
authors.initials: U
authors.lastname: Morandi
authors.forename: Rossano
authors.initials: R
authors.lastname: Dallari
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007421:Intestine, Small / Q000473:pathology / Q000601:surgery; D008168:Lung / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000737:chemistry / Q000556:secondary*; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000556:secondary*; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000556:secondary*; D010997:Pleural Neoplasms / Q000737:chemistry / Q000473:pathology*; D011030:Pneumothorax / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor