title: A mariner with crippling arthritis and bleeding eyes.
abstract: A 41-year-old mariner developed acute arthritis affecting his legs more than his arms or hands during a violent storm on his return from the first of four voyages of discovery. He experienced repeated attacks of the arthritis over the ensuing 14 years, which on at least two occasions were accompanied by painful eyes "much affected with bleeding." He died shortly before his 55 birthday "quite paralyzed and bedridden." Who was he, and what was the likely etiology of his disorder?
authors.affiliation: Department of Medicine, University of Texas Medical School at Houston, Houston, Texas, USA.
authors.forename: Frank C
authors.initials: FC
authors.lastname: Arnett
authors.forename: Charles
authors.initials: C
authors.lastname: Merrill
authors.forename: Francesc
authors.initials: F
authors.lastname: Albardaner
authors.forename: Philip A
authors.initials: PA
authors.lastname: Mackowiak
mesh_terms: D016918:Arthritis, Reactive / Q000175:diagnosis* / Q000266:history*; D003231:Conjunctivitis / Q000175:diagnosis* / Q000266:history*; D003937:Diagnosis, Differential; D005197:Famous Persons; D015796:HLA-B27 Antigen / Q000235:genetics; D049668:History, 15th Century; D049669:History, 16th Century; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D015796:HLA-B27 Antigen