title: Subjective cognitive function and decline among older adults with psychometrically defined amnestic MCI.
abstract: OBJECTIVE
  To examine the relationship between subjective cognitive function and subsequent cognitive decline among individuals with psychometrically defined amnestic mild cognitive impairment (MCI), and to determine whether the presence of depressive symptoms modifies this relationship.
  
  
  METHODS
  Fifty-five individuals met psychometric criteria for amnestic mild cognitive impairment (MCI). Cognitive decline was measured using the Mini-Mental State Examination (MMSE), which was administered at baseline and at follow-up two years later. Subjective cognitive function was examined using two different one-item memory complaints, as well as a scale focused on current level of cognitive function relative to past function and a scale focused on forgetting in specific everyday situations.
  
  
  RESULTS
  In multiple regression analyses, the one-item complaint of change in memory at baseline predicted future cognitive decline. There was a significant interaction effect whereby this association was stronger in participants who endorsed fewer symptoms of depression.
  
  
  CONCLUSIONS
  Individuals showing memory deficits consistent with amnestic MCI have at least some insight regarding cognitive decline and the extent to which subjective cognitive function is useful in predicting future decline may depend on what particular questions are asked as well as presence of depressive symptoms.
authors.affiliation: Department of Psychology, University of Alabama at Birmingham, AL 35294, USA. mgcrowe@uab.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Crowe
authors.forename: Ross
authors.initials: R
authors.lastname: Andel
authors.forename: Virginia
authors.initials: V
authors.lastname: Wadley
authors.forename: Sarah
authors.initials: S
authors.lastname: Cook
authors.forename: Frederick
authors.initials: F
authors.lastname: Unverzagt
authors.forename: Michael
authors.initials: M
authors.lastname: Marsiske
authors.forename: Karlene
authors.initials: K
authors.lastname: Ball
mesh_terms: D000368:Aged; D000647:Amnesia / Q000523:psychology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology*; D003863:Depression / Q000523:psychology; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics