Fecal viral load and norovirus-associated gastroenteritis.
We report the median cDNA viral load of norovirus genogroup II is >100-fold higher than that of genogroup I in the fecal specimens of patients with norovirus-associated gastroenteritis. We speculate that increased cDNA viral load accounts for the higher transmissibility of genogroup II strains through the fecal-oral route.
Chan
Martin C W
MC
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, People's Republic of China.
Sung
Joseph J Y
JJ
Lam
Rebecca K Y
RK
Chan
Paul K S
PK
Lee
Nelson L S
NL
Lai
Raymond W M
RW
Leung
Wai K
WK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017250:Caliciviridae Infections / Q000821:virology; D002648:Child; D002675:Child, Preschool; D018076:DNA, Complementary / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D005243:Feces / Q000821:virology*; D005260:Female; D005759:Gastroenteritis / Q000821:virology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D019562:Viral Load
D018076:DNA, Complementary; D004279:DNA, Viral