Asymptomatic circulation of HEV71 in Norway.
Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype C1. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5'UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence.
Witsø
Elisabet
E
Norwegian Institute of Public Health, Oslo, Norway.
Palacios
Gustavo
G
Rønningen
Kjersti S
KS
Cinek
Ondrej
O
Janowitz
Diana
D
Rewers
Marian
M
Grinde
Bjørn
B
Lipkin
W Ian
WI
D020121:5' Untranslated Regions / Q000235:genetics; D000595:Amino Acid Sequence; D002353:Carrier State / Q000453:epidemiology*; D015331:Cohort Studies; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D004770:Enterovirus / Q000145:classification / Q000235:genetics*; D004769:Enterovirus Infections / Q000453:epidemiology*; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009664:Norway / Q000453:epidemiology; D010802:Phylogeny; D011446:Prospective Studies; D016415:Sequence Alignment; D013045:Species Specificity; D014764:Viral Proteins / Q000235:genetics
D020121:5' Untranslated Regions; D014764:Viral Proteins; D012321:DNA-Directed RNA Polymerases