title: A case of 'hit-and-run' in Plasmodium genetics.
abstract: The ability to genetically manipulate species of the genus Plasmodium, some of which are causative organisms of malaria, has seen significant advances in the past 13 years. However, one major tool that has been lacking is the ability to undertake reverse genetics and 'hit-and-run' mutagenesis. This deficiency has been addressed in the Plasmodium berghei model.
authors.affiliation: Queensland Institute of Medical Research, Herston, 4006 Queensland, Australia.
authors.forename: Donald L
authors.initials: DL
authors.lastname: Gardiner
authors.forename: Michael F
authors.initials: MF
authors.lastname: Good
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D018390:Gene Targeting; D005819:Genetic Markers; D005822:Genetic Vectors; D006801:Humans; D008288:Malaria / Q000517:prevention & control; D009154:Mutation; D010962:Plasmodium berghei / Q000235:genetics* / Q000378:metabolism; D015800:Protozoan Proteins / Q000235:genetics; D011995:Recombination, Genetic; D013045:Species Specificity; D014170:Transformation, Genetic
chemical_list: D005819:Genetic Markers; D015800:Protozoan Proteins