Concurrent occurrence of three primary neoplasms with different hystotype in the same kidney, associated with an adenoma of the omolateral adrenal gland: first case report.
We present an unusual case of concurrent occurrence of three synchronous primary tumors in the same kidney (oncocytoma, chromophobe renal cell carcinoma, angiomyolipoma) associated to an adenoma of the omolateral adrenal gland in a patient with no evident clinical symptoms. The immunohistochemistry showed a positivity for KIT in oncocytoma and chromophobe cell carcinoma, and a weak positivity in the angiomyolipoma, only in the cells positive for HMB-45. This is the first report of this kind of presentation.
Morelli
Luca
L
Department of Anatomic Pathology, S. Maria del Carmine Hospital, Rovereto, Italy. luca.morelli@apss.tn.it
Pusiol
Teresa
T
Piscioli
Irene
I
Larosa
Michelangelo
M
Pozzoli
Gian Luigi
GL
Monica
Bruno
B
D000236:Adenoma / Q000473:pathology*; D018249:Adenoma, Oxyphilic / Q000473:pathology*; D000310:Adrenal Gland Neoplasms / Q000473:pathology*; D000368:Aged; D018207:Angiomyolipoma / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*