title: [Seroprevalence of Anaplasma phagocytophilum infection in dogs in Germany].
abstract: To determine the prevalence of Anaplasma phagocytophilum in dogs in Germany serum samples from 1124 dogs that were under suspicion of having anaplasmosis were examined. The samples were tested by an indirect immunofluorescence test (OFT) for antibodies to A. phagocytophilum. The geographical origin of positive cases were analysed with an geographic information system. Antibodies to A. phagocytophilum were found in 563 (50.1%) of the tested dogs. 166 dogs came from Saarland, 161 from North Rhine-Westphalia, 134 from Baden-Wuerttemberg, 33 from Bavaria, 22 from Rhineland-Palatinate, 11 from Hamburg, 10 from Brandenburg, 9 from Lower Saxony, 8 from Hesse and Berlin respectively and 1 from Schleswig-Holstein. Clinical signs and laboratory findings of 26 seropositive dogs were analysed. Those dogs showed a low haematocrit, thrombocytopenia and leucocytoses as well as higher values for alkaline phosphatase, ALAT und bilirubin. The clinical signs were lameness in 13 dogs, lethargy in 5, and uveitis in 3 dogs. Rhinitis and lymphadenopathy was found in 2 dogs and retinal detachment with blindness in 1 dog.
authors.affiliation: Tierärztliche Labor Freiburg, Freiburg i.Br. barutzki@uni-freiburg.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Barutzki
authors.forename: Alberto
authors.initials: A
authors.lastname: De Nicola
authors.forename: Michela
authors.initials: M
authors.lastname: Zeziola
authors.forename: Markus
authors.initials: M
authors.lastname: Reule
mesh_terms: D041081:Anaplasma phagocytophilum / Q000276:immunology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D004283:Dog Diseases / Q000453:epidemiology*; D004285:Dogs; D016873:Ehrlichiosis / Q000453:epidemiology / Q000662:veterinary*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D005858:Germany / Q000453:epidemiology; D008297:Male; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial