Changes of brachial flow-mediated vasodilation in different ischemic stroke subtypes.
The relationship between endothelial dysfunction and stroke subtypes is unclear. We prospectively measured brachial flow-mediated vasodilation (FMD) in 143 patients with acute ischemic stroke and 40 controls. The overall stroke patients had impaired FMD, but only lacunar infarction had significantly impaired FMD vs the controls. Impaired FMD was an independent predictor for lacunar infarction. Ischemic stroke is associated with endothelial dysfunction, which is more conspicuous in lacunar infarction.
Chen
P L
PL
Section of Neurology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung-Kang Rd., Taichung 407, Taiwan, ROC.
Wang
P Y
PY
Sheu
W H
WH
Chen
Y T
YT
Ho
Y P
YP
Hu
H H
HH
Hsu
H Y
HY
D000368:Aged; D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D020520:Brain Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology; D002318:Cardiovascular Diseases; D016022:Case-Control Studies; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012039:Regional Blood Flow / Q000502:physiology*; D012189:Retrospective Studies; D020521:Stroke / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D014463:Ultrasonography / Q000379:methods; D014664:Vasodilation / Q000502:physiology*