Nickel catalyzed stereoselective conjugate addition of dimethylzinc upon aldimines across 1,3-dien-8-ynes and 1,3-dien-9-ynes.
Ni(acac)2 catalyzes the five-component connection reaction of Me2Zn, alkynes, diene (of 1,3-dien-8-ynes and 1,3-dien-9-ynes), aldehydes and anisidine to furnish cyclic dienyl amines anti-2 with high remote 1,5-diastereoselectivity.
Kimura
Masanari
M
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki, 852-8521, Japan.
Mori
Masahiko
M
Mukai
Nahoko
N
Kojima
Keisuke
K
Tamaru
Yoshinao
Y