Left and right ventricular function is impaired in Behçet's disease.
OBJECTIVE
Subclinical cardiac involvement may occur in patients with Behçet's disease (BD). The purpose of our study was to assess the noninvasive parameters of biventricular function derived from Doppler tissue imaging (DTI) of the tricuspid and mitral annular motion in BD.


METHODS
Twenty-one patients with BD and 20 control subjects were enrolled in this study. All subjects were selected to exclude those with cardiovascular risk factors. Standard echocardiography and pulsed DTI were obtained in every patient.


RESULTS
Peak systolic (13.71 +/- 2.09 vs 20.01 +/- 1.57, P < 0.001), peak early diastolic (11.26 +/- 2.52 vs 15.35 +/- 2.06, P < 0.001) tricuspid annular velocities were significantly lower in patients than controls. Peak systolic (8.68 +/- 1.4 vs 12.25 +/- 1.7, P < 0.001), peak early diastolic (7.89 +/- 1.07 vs 9.94 +/- 1.12, P < 0.001), and peak end diastolic (8.30 +/- 1.32 vs 9.23 +/- 0.91, P = 0.013) lateral mitral annular velocities were significantly lower in patients than controls.


CONCLUSIONS
We demonstrated that myocardial velocities, were affected in patients with BD. Therefore, we conclude that right and left ventricular function is impaired in patients with BD.
Yavuz
Bunyamin
B
Faculty of Medicine, Department of Cardiology, Hacettepe University, Cinnah caddesi No. 11/6, Ankara, Turkey. byavuz.md@yahoo.com
Sahiner
Levent
L
Akdogan
Ali
A
Abali
Gulcan
G
Aytemir
Kudret
K
Tokgozoglu
Lale
L
Kalyoncu
Umut
U
Karadag
Omer
O
Kiraz
Sedat
S
Ertenli
Ihsan
I
Calguneri
Meral
M
Nazli
Nasih
N
D000328:Adult; D000704:Analysis of Variance; D001528:Behcet Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D009200:Myocardial Contraction; D012107:Research Design; D013318:Stroke Volume; D014261:Tricuspid Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D014421:Turkey; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000503:physiopathology*; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right