title: Eccrine porocarcinoma and Bowen's disease arising in a seborrhoeic keratosis.
abstract: An association between seborrhoeic keratosis (SK) and malignant tumours is considered to be rare. We observed a case of eccrine porocarcinoma and Bowen's disease (BD) occurring synchronously, forming one lesion in a SK on the abdomen. It is controversial whether malignant neoplasms arising in SK occur only by chance or if pre-existing SK plays a role in pathogenesis. This case suggests an implication of pre-existing SK in the subsequent development of both BD and eccrine porocarcinoma.
authors.affiliation: Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
authors.forename: D
authors.initials: D
authors.lastname: Hoshina
authors.forename: M
authors.initials: M
authors.lastname: Akiyama
authors.forename: H
authors.initials: H
authors.lastname: Hata
authors.forename: S
authors.initials: S
authors.lastname: Aoyagi
authors.forename: K C
authors.initials: KC
authors.lastname: Sato-Matsumura
authors.forename: H
authors.initials: H
authors.lastname: Shimizu
mesh_terms: D000369:Aged, 80 and over; D001706:Biopsy; D001913:Bowen's Disease / Q000473:pathology*; D002277:Carcinoma / Q000473:pathology*; D004439:Eccrine Glands; D005260:Female; D006801:Humans; D017492:Keratosis, Seborrheic / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*