[Functional insufficiency of the venous valve apparatus and venous return from the lower extremities in humans during the standing test].
The studies were performed with participation of 16 normal subjects with the US Doppler evidence of functional insufficiency of the deep vein valves in a lower extremity. Valve insufficiency was of the latent clinical form without symptoms of chronic venous insufficiency. Functioning of the contralateral leg venous valves was normal in all subjects. Linear velocities of blood flow in the femoral vein in both extremities in the horizontal and vertical position were compared. In the horizontal position, outflow from the deep vein with valve disfunction was 1.5 times (p<0.01) higher comparing with the other leg as the control. In vertical subjects, outflow from the compromised vein was, on the contrary, reduced almost by half as compared with the healthy leg. These features of local phlebohemodynamics at the outlet of insufficient vein appear to determine the intensity of passive mechanic blood redistribution driven by the gravity.
Modin
A Iu
AIu
D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D005080:Exercise Test; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D011187:Posture / Q000502:physiology*; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology*