title: Acute pulmonary aspergillosis in immunocompetent subjects after exposure to bark chippings.
abstract: We describe 2 cases of immunocompetent males with acute community-acquired invasive pulmonary aspergillosis developing shortly after spreading bark chippings. One patient with a fatal outcome was initially diagnosed as allergic alveolitis rather than infection and received steroid treatment illustrating the obvious challenges in the differential diagnosis between these disease entities.
authors.affiliation: Unit of Mycology and Parasitology, Statens Serum Institute, Copenhagen, Denmark. mad@ssi.dk
authors.forename: Maiken Cavling
authors.initials: MC
authors.lastname: Arendrup
authors.forename: B Ronan
authors.initials: BR
authors.lastname: O'driscoll
authors.forename: Eskild
authors.initials: E
authors.lastname: Petersen
authors.forename: David W
authors.initials: DW
authors.lastname: Denning
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000627:therapeutic use; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D024301:Plant Bark / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D017964:Itraconazole; D000666:Amphotericin B