title: BNArray: an R package for constructing gene regulatory networks from microarray data by using Bayesian network.
abstract: BNArray is a systemized tool developed in R. It facilitates the construction of gene regulatory networks from DNA microarray data by using Bayesian network. Significant sub-modules of regulatory networks with high confidence are reconstructed by using our extended sub-network mining algorithm of directed graphs. BNArray can handle microarray datasets with missing data. To evaluate the statistical features of generated Bayesian networks, re-sampling procedures are utilized to yield collections of candidate 1st-order network sets for mining dense coherent sub-networks.
  
  
  BACKGROUND
  The R package and the supplementary documentation are available at http://www.cls.zju.edu.cn/binfo/BNArray/.
authors.affiliation: Department of Bioinformatics Zhejiang University, Hangzhou 310058, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Chen
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Kaida
authors.initials: K
authors.lastname: Ning
mesh_terms: D000465:Algorithms; D001499:Bayes Theorem; D003198:Computer Simulation; D020869:Gene Expression Profiling / Q000379:methods*; D005786:Gene Expression Regulation / Q000502:physiology*; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011381:Programming Languages; D020543:Proteome / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D012984:Software
chemical_list: D020543:Proteome