title: [Surveillance on pathogens of meningococcal meningitis in Beijing, 2005].
abstract: OBJECTIVE
  To study the pathogens of meningococcal meningitis (MM) in Beijing, 2005.
  
  
  METHODS
  Blood and cerebrospinal fluid specimens from MM patients were detected by polymerase chain reaction. Bacterial strains were analyzed by pulsed-field gel electrophoresis and multilocus sequence typing.
  
  
  RESULTS
  7 of the blood and 5 of cerebrospinal fluid specimens showed positive results. 105 of the Neisseria meningitides strains were isolated from the specimens of patients, close contacts and healthy carriers. Serogroup A and C Neisseria meningitides strains shared the same patterns of pulsed-fieldgel electrophoresis, respectively. The sequence type of serogroup A Neisseria meningitides belonged to ST7 while the sequence type of serogroup C Neisseria meningitides belonged to ST4821.
  
  
  CONCLUSIONS
  Patients suffered from meningococcal meningitis were caused by serogroup A (ST7) and C (ST4821) Neisseria meningitides in Beijing, 2005.
authors.affiliation: Institute of Immunization and Prevention of Beijing Center for Disease Prevention and Control, Beijing 100013, China.
authors.forename: Tie-gang
authors.initials: TG
authors.lastname: Zhang
authors.forename: Xiong
authors.initials: X
authors.lastname: He
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: Chen
authors.forename: Jing-guo
authors.initials: JG
authors.lastname: He
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
mesh_terms: D002681:China; D004269:DNA, Bacterial / Q000032:analysis; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008585:Meningitis, Meningococcal / Q000382:microbiology*; D038381:Neisseria meningitidis, Serogroup A / Q000235:genetics* / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial