Cerebral malaria in spite of peripheral parasite clearance in a patient treated with atovaquone/proguanil.
Cerebral malaria, the most frequent complication of falciparum malaria, is usually predicted by an increased count of asexual parasites in peripheral blood. We report a case of a female returnee from Ghana who developed cerebral malaria in spite of parasite clearance in peripheral blood after therapy with atovaquone/proguanil.
Koch
Stefanie
S
Clinics for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Göbels
Klaus
K
Richter
Joachim
J
Oette
Mark
M
Häussinger
Dieter
D
D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D037621:Artemisinins / Q000627:therapeutic use; D000077332:Artesunate; D053626:Atovaquone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016779:Malaria, Cerebral / Q000188:drug therapy* / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000302:isolation & purification; D002727:Proguanil / Q000627:therapeutic use*; D011803:Quinine / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000627:therapeutic use
D000962:Antimalarials; D037621:Artemisinins; D012717:Sesquiterpenes; D000077332:Artesunate; D011803:Quinine; D002727:Proguanil; D053626:Atovaquone