Juvenile fibrocalculous pancreatopathy--a patient report.
Fibrocalculous pancreatopathy (FCPP) is a secondary form of diabetes mellitus (DM) with obscure etiology. Recently various gene mutations have been reported in patients with FCPP from the Indian subcontinent. Initially termed tropical pancreatic diabetes, FCPP is uncommon and is characterized by pancreatic calcifications. The diagnosis is made in the third decade of life in most patients with the onset of abdominal pain and DM. We report a female child with DM diagnosed at the age of 3 years who had been managed with insulin but was ketosis resistant. The diagnosis of FCPP was made 3 years later. There were no mutations at N34S and P55S in the SPINK1 gene.
Bashir
Mir Iftikhar
MI
Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir.
Misgar
Raiz Ahmad
RA
Wani
Arshad Iqbal
AI
Gupta
Vipen
V
Masoodi
Shariq Rashid
SR
Chandak
Giriraj Ratan
GR
Zargar
Abdul Hamid
AH
D002648:Child; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007194:India; D009154:Mutation; D010182:Pancreatic Diseases / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000235:genetics* / Q000378:metabolism
D014359:Trypsin Inhibitor, Kazal Pancreatic