title: Potential complications of ocular surgery in patients with coexistent keratoconus and Fuchs' endothelial dystrophy.
abstract: OBJECTIVE
  To describe the potential complications of cataract and refractive surgery in patients with Fuchs' endothelial dystrophy (FED) and keratoconus.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Eight patients with FED and keratoconus in a large university group practice.
  
  
  METHODS
  We reviewed the clinical and topographic findings of 8 patients (15 eyes) with FED and keratoconus. Clinical examination, corneal topography, specular microscopy were done, and sequential central corneal thickness (CCT) was obtained. Follow-up ranged from 1 month to 6 years.
  
  
  METHODS
  Findings of keratoconus and FED in preoperative evaluation.
  
  
  RESULTS
  Five patients had concomitant cataracts; 3 had refractive errors and sought surgical correction. Cataract surgery was performed on 3 of 5 patients (5 eyes). LASIK was performed on one eye of 3 patients. Of 5 eyes that underwent cataract extraction, 4 had blurry vision after surgery. The interval between the surgical procedure and onset of symptoms ranged from 1 month to 4 years. The causes of decreased vision after cataract surgery were corneal edema and/or corneal ectasia. The CCT readings ranged from 426 to 824 microm. One of 4 symptomatic eyes underwent penetrating keratoplasty. The CCTs of 3 patients (6 eyes) who presented with refractive error ranged from 507 to 565 microm. One eye had undergone an attempted LASIK procedure resulting in a lost cap. Corneal topography and specular microscopy showed the coexistence of keratoconus and FED, and the patients were advised against having LASIK surgery.
  
  
  CONCLUSIONS
  Corneal thinning caused by keratoconus and concurrent increase in corneal thickness caused by FED may combine to normalize the corneal pachymetry readings; disease severity may be underestimated, which may lead to unexpected postoperative visual outcomes. Routine use of preoperative topography and specular microscopy may help to avert potential surgical complications.
authors.affiliation: Cornea and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Ula
authors.initials: U
authors.lastname: Jurkunas
authors.forename: Dimitri T
authors.initials: DT
authors.lastname: Azar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications* / Q000628:therapy; D003315:Cornea / Q000000981:diagnostic imaging / Q000473:pathology; D019781:Corneal Topography; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000150:complications*; D006801:Humans; D007640:Keratoconus / Q000150:complications*; D020731:Keratomileusis, Laser In Situ; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications; D012030:Refractive Errors / Q000150:complications*; D054140:Refractive Surgical Procedures; D012189:Retrospective Studies; D014463:Ultrasonography; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity