title: Orbital cysts lined with both stratified squamous and columnar epithelia: a late complication of silicone implants.
abstract: Two patients presented with orbital cysts 5 and 7 years after orbital blowout fracture repair with silicone plate implants. The orbital cysts caused significant exophthalmos and restriction in ocular motility. Surgical excision revealed thick-walled cysts that were displacing the globe and encapsulating the silicone implant. On histopathologic examination, the cysts were lined with both stratified squamous and ciliated columnar (respiratory) epithelia. We propose that squamous and respiratory epithelial cells may have been deposited during surgery from the conjunctival and sinus epithelia, respectively. This case series illustrates that although an uncommon complication, epithelium-lined inclusion cysts may develop several years after orbital fracture repair with a silicone implant. A transconjunctival surgical approach is a possible risk factor.
authors.affiliation: The Eye Institute at Tan Tock Seng Hospital, Singapore.
authors.forename: Colin S H
authors.initials: CS
authors.lastname: Tan
authors.forename: Leonard P K
authors.initials: LP
authors.lastname: Ang
authors.forename: Chai-Teck
authors.initials: CT
authors.lastname: Choo
authors.forename: Elizabeth S T
authors.initials: ES
authors.lastname: Cheah
authors.forename: Soon-Phaik
authors.initials: SP
authors.lastname: Chee
mesh_terms: D000328:Adult; D003560:Cysts / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D009917:Orbital Fractures / Q000601:surgery; D020273:Orbital Implants / Q000009:adverse effects*; D019919:Prosthesis Implantation / Q000295:instrumentation; D012826:Silicone Elastomers / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D012826:Silicone Elastomers