[Pancreatic hormones and hormonal regulation of insulin secretion].
Endocrine pancreas producing insulin, glucagon, somatostatin and pancreatic polypeptide is under the influence of different types of regulation; among them the regulatory role of enteropancreatic axis plays an important role. Incretin effect of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) is significantly involved in the insulin secretion which is modulated by many other hormones. Diabetes mellitus, similarly to disturbances of other hormones, can cause impaired regulation of insulin and other pancreatic hormones.
Skrha
J
J
III interní klinika 1 LF UK a VFN, Praha. jan.skrha@lf1.cuni.cz
D005749:Gastric Inhibitory Polypeptide / Q000502:physiology*; D052216:Glucagon-Like Peptide 1 / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D010187:Pancreatic Hormones / Q000502:physiology*
D007328:Insulin; D010187:Pancreatic Hormones; D005749:Gastric Inhibitory Polypeptide; D052216:Glucagon-Like Peptide 1