title: Oxybutynin in detrusor overactivity.
abstract: Oxybutynin has been used for the management of detrusor overactivity for over 30 years and has withstood medical scrutiny and the test of time throughout the world. Although several agents in the class of bladder relaxants have only recently been studied, oxybutynin's effectiveness in reducing urinary frequency and urge urinary incontinence is unquestioned in the medical literature. Oxybutynin is extremely safe and effective in almost every population including children, the elderly, and those who have neurogenic bladder. With more preparations available and more dosing flexibility than any other anticholinergic medication on the market, oxybutynin remains the "gold standard" for first-line therapy for patients who have detrusor overactivity.
authors.affiliation: Department of Urology, William Beaumont Hospital, 3535 W. Thirteen Mile Road, Suite 438, Royal Oak, MI 48073, USA. adiokno@beaumont.edu
authors.forename: Ananias
authors.initials: A
authors.lastname: Diokno
authors.forename: Michael
authors.initials: M
authors.lastname: Ingber
mesh_terms: D006801:Humans; D008333:Mandelic Acids / Q000627:therapeutic use*; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
chemical_list: D008333:Mandelic Acids; D018727:Muscarinic Antagonists; C005419:oxybutynin