title: Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop.
abstract: The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.
authors.affiliation: Food Standards Agency, Aviation House, London WC2B 6NH, UK. mamta.singh@foodstandards.gsi.gov.uk
authors.forename: Mamta
authors.initials: M
authors.lastname: Singh
authors.forename: Margaret
authors.initials: M
authors.lastname: Ashwell
authors.forename: Peter
authors.initials: P
authors.lastname: Sanderson
authors.forename: Janet
authors.initials: J
authors.lastname: Cade
authors.forename: Jennifer
authors.initials: J
authors.lastname: Moreton
authors.forename: Susan
authors.initials: S
authors.lastname: Fairweather-Tait
authors.forename: Mark
authors.initials: M
authors.lastname: Roe
authors.forename: Joannes J M
authors.initials: JJ
authors.lastname: Marx
authors.forename: Mark
authors.initials: M
authors.lastname: Worwood
authors.forename: James D
authors.initials: JD
authors.lastname: Cook
mesh_terms: D050197:Atherosclerosis / Q000209:etiology; D004032:Diet; D020022:Genetic Predisposition to Disease; D006432:Hemochromatosis / Q000235:genetics; D000071020:Hemochromatosis Protein; D006579:Heterozygote; D015395:Histocompatibility Antigens Class I / Q000235:genetics; D006801:Humans; D019190:Iron Overload / Q000150:complications / Q000235:genetics*; D019266:Iron, Dietary / Q000493:pharmacokinetics; D008565:Membrane Proteins / Q000235:genetics; D009154:Mutation
chemical_list: C103673:HFE protein, human; D000071020:Hemochromatosis Protein; D015395:Histocompatibility Antigens Class I; D019266:Iron, Dietary; D008565:Membrane Proteins