[Protein microarray biosensor based on imaging ellipsometry and its biomedical applications].
A protein microarray biosensor based on imaging ellipsometry has been developed as a high-throughput and fast technique for protein analysis. As an automatic technique, it has advanced properties such as label-free, multi-protein simultaneous detection, static or kinetic analysis for protein interaction, and qualitative or quantitative analysis. It has been used for the biomedical applications including tumor markers detection, hepatitis B test, protein competitive adsorption and kinetic visualization for protein interactions. It have demonstrated promising potential for further applications in biomedicine.
Chen
Yan-Yan
YY
National Microgravity Laboratory, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, China.
Jin
Gang
G
D015374:Biosensing Techniques / Q000379:methods* / Q000639:trends*; D006801:Humans; D040081:Protein Array Analysis / Q000379:methods* / Q000639:trends*