title: Characterization strategies for the functional assessment of the cutaneous lesion.
abstract: Assessment of wound healing is a complex task, especially when the lesion is associated to significant (full thickness) loss of the skin. The clinical observation, essentially subjective and highly dependent on the observer's experience, creates difficulties in the comparison of results. Scoring scales were introduced in the clinical practice to create comparable semi-quantitative data and promote better management of resources, but its usefulness in a clinical perspective is still limited. New non-invasive biometric methodologies, although infrequently used, have opened new possibilities. While complementing the clinical observation and contributing to therapeutic decisions and prognosis, they may also help to look further into the pathophysiological mechanisms of scarring drugs rehabilitation. Following previous work in this arena, the authors review, the state-of-the-art of cutaneous wound healing clinical and biometric follow up, proposing a diagnosis correlation for the most relevant descriptors found in both strategies in order to fully characterise the different stages of the healing process.
authors.affiliation: Cutaneous Biology Laboratory (UCTF), Faculdade de Farmácia da Universidade de Lisboa, Av. das Forças Armadas, 1649-019 Lisbon, Portugal. monteirorodrigues@mail.telepac.pt
authors.forename: Luís Monteiro
authors.initials: LM
authors.lastname: Rodrigues
authors.forename: Maria Angélica
authors.initials: MA
authors.lastname: Roberto
mesh_terms: D001699:Biometry / Q000379:methods; D002056:Burns / Q000473:pathology / Q000503:physiopathology*; D002245:Carbon Dioxide / Q000097:blood; D002921:Cicatrix / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D012867:Skin / Q000098:blood supply / Q000737:chemistry / Q000293:injuries*; D014945:Wound Healing / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen