title: Juvenile fibrocalculous pancreatopathy--a patient report.
abstract: Fibrocalculous pancreatopathy (FCPP) is a secondary form of diabetes mellitus (DM) with obscure etiology. Recently various gene mutations have been reported in patients with FCPP from the Indian subcontinent. Initially termed tropical pancreatic diabetes, FCPP is uncommon and is characterized by pancreatic calcifications. The diagnosis is made in the third decade of life in most patients with the onset of abdominal pain and DM. We report a female child with DM diagnosed at the age of 3 years who had been managed with insulin but was ketosis resistant. The diagnosis of FCPP was made 3 years later. There were no mutations at N34S and P55S in the SPINK1 gene.
authors.affiliation: Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir.
authors.forename: Mir Iftikhar
authors.initials: MI
authors.lastname: Bashir
authors.forename: Raiz Ahmad
authors.initials: RA
authors.lastname: Misgar
authors.forename: Arshad Iqbal
authors.initials: AI
authors.lastname: Wani
authors.forename: Vipen
authors.initials: V
authors.lastname: Gupta
authors.forename: Shariq Rashid
authors.initials: SR
authors.lastname: Masoodi
authors.forename: Giriraj Ratan
authors.initials: GR
authors.lastname: Chandak
authors.forename: Abdul Hamid
authors.initials: AH
authors.lastname: Zargar
mesh_terms: D002648:Child; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007194:India; D009154:Mutation; D010182:Pancreatic Diseases / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000235:genetics* / Q000378:metabolism
chemical_list: D014359:Trypsin Inhibitor, Kazal Pancreatic