title: Primary and secondary tumours occurring simultaneously in the brain of a dog.
abstract: Primary brain tumours of a single histological type and metastatic brain tumours are well described in dogs in the current veterinary literature. However, the concurrent presence of a primary and secondary tumour in the brain of a dog has never, to the authors' knowledge, been previously reported. The clinical and pathological features of a nine-year-old, female boxer with an oligodendroglioma and metastases from a mammary gland adenocarcinoma occurring simultaneously in the brain are described in this case report. Information in the veterinary literature on multiple malignancies affecting the central nervous system is very limited; therefore, a discussion about comparative situations in human medicine has been included.
authors.affiliation: Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro, PO Box 1013, 5001-911 Vila Real, Portugal.
authors.forename: A
authors.initials: A
authors.lastname: Alves
authors.forename: J
authors.initials: J
authors.lastname: Prada
authors.forename: J M
authors.initials: JM
authors.lastname: Almeida
authors.forename: I
authors.initials: I
authors.lastname: Pires
authors.forename: F
authors.initials: F
authors.lastname: Queiroga
authors.forename: S R
authors.initials: SR
authors.lastname: Platt
authors.forename: A S P
authors.initials: AS
authors.lastname: Varejão
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000473:pathology*; D009362:Neoplasm Metastasis; D009837:Oligodendroglioma / Q000556:secondary / Q000662:veterinary*