Serum endostatin levels in gastric cancer patients: correlation with clinicopathological parameters.
OBJECTIVE
The aim of this study was to evaluate the predictive role of the circulating levels of endostatin in gastric cancer patients.


METHODS
This study is a retrospective case-control study. We measured serum endostatin levels of 30 patients aged between 34-83 years with gastric cancer and 30 patients without malignant pathology operated for benign pathologies with age ranging from 18 to 69.


RESULTS
Serum levels of endostatin were correlated with the Lauren classification. Significantly higher serum endostatin levels were obtained in Lauren intestinal type tumors than Lauren diffuse type tumors.


CONCLUSIONS
These data suggest that serum endostatin levels do not correlate with clinicopathological parameters, except tumor histopathology (according to Lauren classification), in gastric cancer patients.
Koç
Mahmut
M
Fifth Department of Surgery, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Göçmen
Erdal
E
Kiliç
Mehmet
M
Ozbay
Mete
M
Oktem
Murat
M
Tez
Mesut
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020533:Angiogenesis Inhibitors / Q000097:blood*; D016022:Case-Control Studies; D043169:Endostatins / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic; D013274:Stomach Neoplasms / Q000097:blood / Q000473:pathology*
D020533:Angiogenesis Inhibitors; D043169:Endostatins