[A 54-year-old man with a large subcutaneous skull erosion and focal epileptic seizures].
BACKGROUND
Extracranial metastases from meningioma are rare, and are reported to occur in less than 1 per 1000.


METHODS
We report a 54-year-old man, who presented with a parasagittal meningioma with skull erosion and overlying soft tissue invasion. Tumour invading the superior sagittal sinus was not removed, and postoperative radiation was therefore delivered to the excision site. Histology was consistent with an atypical meningioma. The patient had a re-operation of a recurrence 3.5 years later, and after another year six tumours were detected close to pleura and in the lungs. A biopsy from the largest one demonstrated a metastasis having the same histology as the primary tumour.


CONCLUSIONS
Risk factors for metastasis of cerebral meningiomas have been suggested to be histological malignancy grade, venous sinus invasion, and local recurrences after previous craniotomy.
Vik
Anne
A
Nevrokirurgisk avdeling, St. Olavs Hospital, 7006 Trondheim. anne.vik@ntnu.no
Kvikstad
Anne
A
Unsgård
Geirmund
G
Jørgensen
Jan Valentin
JV
Torp
Sverre Helge
SH
D004828:Epilepsies, Partial / Q000175:diagnosis / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary / Q000601:surgery; D008579:Meningioma / Q000150:complications / Q000473:pathology / Q000556:secondary / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010997:Pleural Neoplasms / Q000473:pathology / Q000556:secondary; D012888:Skull Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary / Q000601:surgery; D014057:Tomography, X-Ray Computed