title: [Day-to day variability of cardiac pressure values in horses measured with right heart catheterization on 3 consecutive days].
abstract: In the present study, a right heart catheterisation was carried out on three consecutive days in 17 healthy horses to evaluate the day-to-day variability of cardiac pressure values. Cardiac pressure values were measured in the right atrium, the right ventricle, the pulmonary artery, and the pulmonary capillaries (pulmonary artery wedge pressure). Additionally it was examined wether the cardiac pressure variability was influenced by the heart rate and if there are differences between trained and untrained horses. Beside the coefficient of variances, statistical analysis with assessment of variance components were carried out. Therefore the variation between repeated measurements at one day and within one horse, and the variation between repeated measurements over three days and within the horses (day to day intraindividual variation) as well as the variation between the horses (interindividual variation) were taken into account. The absolute interindividual variance of the pressure values and the heart rate was between 0.4 and 19.6 at all day and for all horses. Between trained and untrained horses the variation of the pressure values and the heart rate was lower than in the trained horses. A significant difference between trained and untrained horses was seen in right atrial mean pressure (p < 0.001) and right atrial diastolic pressure (p < 0.005). The coefficient of variances of the mean heart rate was 11.8%. The coefficient of variances of the different pressure values ranged between 13.1 (mean pulmonary artery pressure) and 46.4% (right ventricular pressure). By splitting the variances, 54.4-78.9% of the variation was caused by the effect of days, 6.2-30.7% of the variation was caused by the effect of horses and 12.5-23% of the variation was caused by the repeated measurements at the different days. In sumary the results shows that nearly all of the pressure values had a low effect of days on the variation, thus cardiac pressure measurements at one day seem to be sufficient.
authors.affiliation: Klinik für Pferde, Stiftung Tierärztliche Hochschule Hannover. heidrun.gehlen@tiho-hannover.de
authors.forename: Heidrun
authors.initials: H
authors.lastname: Gehlen
authors.forename: Ursula
authors.initials: U
authors.lastname: Groner
authors.forename: Karl
authors.initials: K
authors.lastname: Rohn
authors.forename: Peter
authors.initials: P
authors.lastname: Stadler
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D006328:Cardiac Catheterization / Q000662:veterinary*; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006736:Horses / Q000502:physiology*; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D017725:Ventricular Pressure / Q000502:physiology