title: [Aphakia in a German Holstein calf].
abstract: Aphakia and further malformations of both eyes were diagnosed in a female German Holstein calf. Besides aphakia of the left eye, the calf exhibited microphthalmia, glaucoma and a hypoplastic uveoscleral tissue. Additional findings in the right eye were buphthalmus and glaucoma. Instead of aphakia, pathohistological and investigations revealed a very small (microphakia) and luxated lens. Neither the clinical nor the pathological examination revealed further malformations of other organs. A BVD infection could be excluded as cause for the ocular malformations observed. A deficiency or excess of vitamine A was unlikely because this would have also applied to all other calves born at the same time on the farm. An inbreeding coefficient of 3.168% for the malformed calf and the exclusion of environmental causes for these malformations of the eyes let us suppose a hereditary problem.
authors.affiliation: Institut für Tierzucht und Vererbungsforschung, Stiftung Tierärztliche Hochschule Hannover.
authors.forename: U
authors.initials: U
authors.lastname: Schulze
authors.forename: H
authors.initials: H
authors.lastname: Kuiper
authors.forename: S
authors.initials: S
authors.lastname: Schmidtbauer
authors.forename: P
authors.initials: P
authors.lastname: Wohlsein
authors.forename: A
authors.initials: A
authors.lastname: Krause
authors.forename: L
authors.initials: L
authors.lastname: Haas
authors.forename: O
authors.initials: O
authors.lastname: Distl
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001035:Aphakia / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D005260:Female; D007178:Inbreeding; D010375:Pedigree