title: The 1H NMR method for the determination of the absolute configuration of 1,2,3-prim,sec,sec-triols.
abstract: The absolute configuration of 1,2,3-prim,sec,sec-triols can be assigned by comparison of the 1H NMR spectra of the tris-(R)- and the tris-(S)-MPA ester derivatives. An experimental demonstration of this correlation with 24 triols of known absolute configuration and a protocol using two parameters-Deltadelta(RS)(H3) and the difference between Deltadelta RS (H2) and Deltadelta RS (H3) = absolute value (Delta(Deltadelta RS))-for its application to the determination of the absolute configuration of other triols are presented.
authors.affiliation: Departamento de Química Organica and Unidad de RMN de Biomoléculas Asociada al CSIC, Universidad de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Lallana
authors.forename: Félix
authors.initials: F
authors.lastname: Freire
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Seco
authors.forename: Emilio
authors.initials: E
authors.lastname: Quiñoa
authors.forename: Ricardo
authors.initials: R
authors.lastname: Riguera
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure; D011522:Protons
chemical_list: D000438:Alcohols; D011522:Protons