[Misinterpreted lymphadenopathy and thrombocytopenia as unrecognised initial symptoms of an HIV-infection].
In a 28-year-old woman and a 30-year-old man with lymphadenopathy, shown by histopathology to be follicular hyperplasia, and in a 40-year-old woman and a 40-year-old man with a thrombocytopenia, HIV-infection was not diagnosed until years later. Three of the four patients did not belong to a 'classical high-risk group' for HIV/AIDS. All patients, meanwhile, suffered from minor or major complications. Moreover, the number of CD4+ cells had decreased to < or = 200/microl before antiretroviral therapy was started. After treatment, all four patients were in reasonable to good condition. An HIV-infection should be considered in every case of reactive lymphadenopathy or thrombocytopenia.
Stek
C J
CJ
Medisch Spectrum Twente, afd. Interne Geneeskunde, Postbus 50.000, 7500 KA Enschede. cari_stek@hotmail.com
Kootstra
G J
GJ
ten Napel
Chr H H
CH
D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D013921:Thrombocytopenia / Q000175:diagnosis / Q000209:etiology*
D019380:Anti-HIV Agents; D018501:Antirheumatic Agents