Radiotherapy-related typing in 842 patients in canton with nasopharyngeal carcinoma.
OBJECTIVE
The aim of this study was to propose the clinical radiotherapy-related typing and to summarize proportional distribution of radiotherapy-related types of nasopharyngeal carcinoma (NPC).


METHODS
A total of 842 cases of NPC were randomly selected. According to 5-year follow-up results after radiotherapy, NPC was subdivided into four types: Type I (no primary and regional recurrence and no distant metastasis), Type II (primary or regional recurrence and no distant metastasis), Type III (no primary and regional recurrence, and distant metastasis), and Type IV (primary or regional recurrence, and distant metastasis). Proportion of the four types and relationship between this typing and Zhi-guang Xie typing were analyzed.


RESULTS
Distribution of radiotherapy-related types of NPC were 50.6%, 23.2%, 20.7%, and 5.6% for Types I, II, III, and IV, respectively. For Types D and AD of Zhi-guang Xie typing system and Stage III and IV of the 1992 Fuzhou staging system, the proportion of Type III was greater than that of Type II; and for Type A and Stage I and II, there was a larger proportion of Type II than that of Type III.


CONCLUSIONS
Radiotherapy-related typing, as a new clinical subclassification, could be supplementary for previous clinical typing and staging.
Li
Zhi-qiang
ZQ
State Key Laboratory of Oncology in Southern China, Guangzhou, China.
Xia
Yun-fei
YF
Liu
Qing
Q
Yi
Wei
W
Liu
Xiu-fang
XF
Han
Fei
F
Luo
Wei
W
Lu
Tai-xiang
TX
D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000532:radiotherapy*; D009367:Neoplasm Staging / Q000379:methods* / Q000706:statistics & numerical data; D011379:Prognosis; D020266:Radiotherapy, Conformal / Q000379:methods* / Q000706:statistics & numerical data; D016896:Treatment Outcome