title: Prenylated phenolics from Ganoderma fornicatum.
abstract: Three new prenylated phenolic compounds, fornicins A-C (1-3), were obtained from the fruiting bodies of Ganoderma fornicatum. The structure elucidation was achieved by interpretation of spectroscopic data. These compounds exhibited moderate cytotoxic activity with IC(50) values of 15 to 30 microg/mL in Hep-2 cells.
authors.affiliation: School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Niu
authors.forename: Sheng-Hong
authors.initials: SH
authors.lastname: Li
authors.forename: Han-Dong
authors.initials: HD
authors.lastname: Sun
authors.forename: Chun-Tao
authors.initials: CT
authors.lastname: Che
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D004354:Drug Screening Assays, Antitumor; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032902:Ganoderma / Q000737:chemistry*; D006801:Humans; D020128:Inhibitory Concentration 50; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D005663:Furans; D010636:Phenols; C514410:fornicin A; C514411:fornicin B; C514412:fornicin C