title: An approach to the inheritance of the sesquiterpene chemotypes within Petasites hybridus.
abstract: Sesquiterpene esters are the active principle in the medicinal plant Petasites hybridus. Two chemotypes, the petasin chemotype and the furanopetasin chemotype, are known, but only the first one is suitable for pharmaceutical purposes. Experimental crossings were performed within and between plants of both chemotypes to study the genetic basis of the occurrence of these sesquiterpenes. The chemotype was determined by TLC in extracts of a small piece of rhizome in the parent plants and the progenies. A model including the combined action of two genes is proposed to explain the inheritance of the chemotypes where the furanopetasin chemotype is under recessive genetic control.
authors.affiliation: Institute for Applied Botany and Pharmacognosy, Department of Veterinary Public Health, University of Veterinary Medicine, Veterinaerplatz 12, 1210 Vienna, Austria. Remigius.Chizzola@vu-wien.ac.at
authors.forename: Remigius
authors.initials: R
authors.lastname: Chizzola
authors.forename: Theodor
authors.initials: T
authors.lastname: Langer
authors.forename: Chlodwig
authors.initials: C
authors.lastname: Franz
mesh_terms: D003433:Crosses, Genetic; D004952:Esters / Q000737:chemistry / Q000145:classification; D017343:Genes, Plant; D040582:Inheritance Patterns; D008957:Models, Genetic; D036901:Petasites / Q000737:chemistry* / Q000235:genetics*; D010936:Plant Extracts / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry; D012717:Sesquiterpenes / Q000032:analysis* / Q000737:chemistry / Q000145:classification
chemical_list: D004952:Esters; D010936:Plant Extracts; D012717:Sesquiterpenes