Competence-dependent bacteriocin production by Streptococcus gordonii DL1 (Challis).
The production of streptocins STH(1) and STH(2) by Streptococcus gordonii DL1 (Challis) is directly controlled by the competence regulon, which requires intact comR and comAB loci. The streptocin (sth) locus comprises two functional genes, sthA and sthB. Whereas STH(1) activity requires sthA alone, STH(2) activity depends on both genes.
Heng
Nicholas C K
NC
Department of Oral Sciences, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand. nicholas.heng@stonebow.otago.ac.nz
Tagg
John R
JR
Tompkins
Geoffrey R
GR
D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D001430:Bacteriocins / Q000096:biosynthesis* / Q000235:genetics; D004268:DNA-Binding Proteins / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006460:Hemolysin Proteins / Q000096:biosynthesis* / Q000235:genetics; D013291:Streptococcus / Q000235:genetics* / Q000378:metabolism*
D001426:Bacterial Proteins; D001430:Bacteriocins; C061262:ComA protein, Bacteria; D004268:DNA-Binding Proteins; D006460:Hemolysin Proteins