title: Pyloric obstruction, duodenal dilatation, and extrahepatic cholestasis: a neonatal triad suggesting multiple intestinal atresias.
abstract: Whereas physiologic jaundice constitutes a common finding in neonates, a few cases present with cholestatic jaundice owing to various pathologic conditions, including extrahepatic biliary obstruction. We report the case of a 2-day-old female neonate presenting with neonatal cholestasis, nonbilious vomiting with pyloric obstruction, and multiple intestinal atresias. A pathognomonic clinicoradiologic triad is described, based on clinical data, plain abdominal x-ray, and ultrasound examination.
authors.affiliation: Pediatric Surgery Unit, Saint-Luc University Clinics, Université catholique de Louvain, B-1200 Brussels, Belgium.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Darwish
authors.forename: Christian
authors.initials: C
authors.lastname: Debauche
authors.forename: Philippe
authors.initials: P
authors.lastname: Clapuyt
authors.forename: Zephyrin
authors.initials: Z
authors.lastname: Feruzi
authors.forename: Jean
authors.initials: J
authors.lastname: de Ville de Goyet
authors.forename: Raymond
authors.initials: R
authors.lastname: Reding
mesh_terms: D001651:Cholestasis, Extrahepatic / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic; D004386:Duodenum / Q000503:physiopathology*; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011708:Pylorus; D011860:Radiography, Abdominal; D014463:Ultrasonography