title: Approaches for calculating power for case-cohort studies.
abstract: An approach for determining the power of a case-cohort study for a single binary exposure variable and a low failure rate was recently proposed by Cai and Zeng (2004, Biometrics 60, 1015-1024). In this article, we show that computing power for a case-cohort study using a standard case-control method yields nearly identical levels of power. An advantage of the case-control approach is that existing sample size software can be used for the calculations. We also propose an additional formula for computing the power of a case-cohort study for the situation when the event is not rare.
authors.affiliation: Division of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA. mikim@aecom.yu.edu
authors.forename: Mimi Y
authors.initials: MY
authors.lastname: Kim
authors.forename: Xiaonan
authors.initials: X
authors.lastname: Xue
authors.forename: Yunling
authors.initials: Y
authors.lastname: Du
mesh_terms: D001699:Biometry / Q000379:methods*; D016022:Case-Control Studies; D015331:Cohort Studies; D016021:Epidemiologic Studies; D006801:Humans; D015233:Models, Statistical; D018401:Sample Size