Gefitinib concentrations in human glioblastoma tissue.
Hofer
Silvia
S
Medical Oncology, University Hospital Zürich, Rämistrasse 100, 8091, Zürich, Switzerland. silvia.hofer@usz.ch
Frei
Karl
K
D000970:Antineoplastic Agents / Q000493:pharmacokinetics*; D001682:Biological Availability; D001932:Brain Neoplasms / Q000188:drug therapy / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D066246:ErbB Receptors / Q000037:antagonists & inhibitors; D000077156:Gefitinib; D005909:Glioblastoma / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D011799:Quinazolines / Q000493:pharmacokinetics*
D000970:Antineoplastic Agents; D011799:Quinazolines; D003577:Cytochrome P-450 Enzyme System; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D066246:ErbB Receptors; D000077156:Gefitinib