[Thrombocytopenia and other extrahepatic manifeststions of hepatitis C virus infection--case report].
Authors present a case of forty seven years old woman with thrombocytopenia in the course of hepatitis C virus infection. Thrombocytopenia might be related to immunological mechanisms or be an effect of hypersplenism. Moreover mixed cryoglobulinemia, lymphocytic autoimmune thyroiditis with hypothyroidism and other laboratory abnormalities (impaired rate of lymphocytes CD4 to CD8, increase of B cells and natural killer cells, hypocomplementemia, hypergammaglobulinemia, increase of immune complexes concentration) were revealed. Above-mentioned abnormalities might be an effect of hepatitis C virus infection.
Berendt-Obołończyk
Monika
M
Akademia Medyczna w Gdańsku, Klinika Chorób Wewnetrznych, Endokrynologii i Zaburzeń Hemostazy, Instytut Chorób Wewnetrznych. monika-berendt@wp.pl
Kazimierska
Ewa
E
Sworczak
Krzysztof
K
D001327:Autoimmune Diseases / Q000276:immunology / Q000821:virology; D003449:Cryoglobulinemia / Q000276:immunology / Q000821:virology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D013921:Thrombocytopenia / Q000276:immunology / Q000821:virology*; D013967:Thyroiditis, Autoimmune / Q000276:immunology / Q000821:virology*