Predictors of early mortality in patients with ischemic stroke.
Accurate predictors of early outcome in stroke patients have a number of important applications, such as introducing secondary prevention strategies, supporting treatment decisions or designing randomized clinical trials. Surprisingly, a generally accepted, reliable and well-validated mortality-prediction model is still unavailable. This review outlines the most important predictors of in-hospital mortality that could be assessed at admission to hospital emergency room within 24 h of ischemic stroke onset. A number of factors are discussed such as nonmodifiable factors (e.g., age, gender and genetic factors); type of stroke and its severity - measured by different clinical score scales; predictive models; laboratory markers; special neuroradiological and neurophysiological tests; and comorbid conditions at admission and quality of hospital care.
Kazmierski
Radoslaw
R
Poznan University of Medical Sciences, Department of Neurology, ul. Przybyszewskiego 49, 60-355 Poznan, Poland. R.Kazmierski@am.poznan.pl
D002545:Brain Ischemia / Q000401:mortality*; D015897:Comorbidity; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015995:Prevalence; D011379:Prognosis; D016016:Proportional Hazards Models; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D020521:Stroke / Q000401:mortality*; D016019:Survival Analysis; D015996:Survival Rate