Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett's esophagus.
OBJECTIVE
To report the endoscopic treatment of large hyperplastic polyps of the esophagus and esophago-gastric junction (EGJ) associated with Barrett's esophagus (BE) with low-grade dysplasia (LGD), by endoscopic mucosal resection (EMR).


METHODS
Cap fitted EMR (EMR-C) was performed in 3 patients with hyperplastic-inflammatory polyps (HIPs) and BE.


RESULTS
The polyps were successfully removed in the 3 patients. In two patients, with short segment BE (SSBE) (<= 3 cm), the metaplastic tissue was completely excised. A 2 cm circumferential EMR was performed in one patient with a polyp involving the whole EGJ. A simultaneous EMR-C of a BE-associated polypoid dysplastic lesion measuring 1 cm multiply 10 cm, was also carried out. In the two patients, histologic assessment detected LGD in BE. No complications occurred. Complete neosquamous re-epithelialization occurred in the two patients with SSBE. An esophageal recurrence occurred in the remaining one and was successfully retreated by EMR.


CONCLUSIONS
EMR-C appears to be a safe and effective method for treating benign esophageal mucosal lesions, allowing also the complete removal of SSBE.
De Ceglie
Antonella
A
Corso Garibaldi 187, Sanremo (IM) 3 18038, Italy. mxconio@tin.it
Lapertosa
Gabriella
G
Blanchi
Sabrina
S
Di Muzio
Marcello
M
Picasso
Massimo
M
Filiberti
Rosangela
R
Scotto
Francesco
F
Conio
Massimo
M
D000368:Aged; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004935:Esophageal Diseases / Q000473:pathology* / Q000601:surgery*; D004943:Esophagogastric Junction / Q000473:pathology / Q000601:surgery; D004947:Esophagus / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009092:Mucous Membrane / Q000473:pathology / Q000601:surgery; D011127:Polyps / Q000209:etiology / Q000473:pathology* / Q000601:surgery*