A novel HLA-B*2730 allele found in a Slovene patient affected with IgA nephropathy.
A novel allele HLA-B*2730 and the haplotype HLA-A*03-B*2730-Cw*02-DRB1*16-DRB5 have been found in a Slovene patient and his mother. The exon 2 sequence is identical to that of HLA-B*2702, and the exon 3 sequence is identical to that of HLA-B*2719. A possible mechanism for the generation of B*2730 is a gene conversion event.
Vidan-Jeras
B
B
Tissue Typing Centre, Blood Transfusion Centre of Slovenia, Slajmerjeva, Ljubljana. Slovenia. blanka.vidan-jeras@ztm.si
Kunilo
S
S
Fae
I
I
Kandus
A
A
Fischer
G F
GF
D000328:Adult; D000483:Alleles; D000595:Amino Acid Sequence; D005260:Female; D005922:Glomerulonephritis, IGA / Q000235:genetics* / Q000601:surgery; D015235:HLA-B Antigens / Q000235:genetics*; D015796:HLA-B27 Antigen; D006239:Haplotypes; D006650:Histocompatibility Testing; D006720:Homozygote; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D014181:Transplantation Immunology; D014850:Waiting Lists
D015235:HLA-B Antigens; C515025:HLA-B*27:30 antigen; D015796:HLA-B27 Antigen