[Research advances in the controlled release of growth factor related to blood vessel tissue engineering].
Growth factors play an important role in cell adhesion and proliferation as well as in tissue regeneration. By incorporating growth factors into polymer scaffolds, controlled release of them can be performed. The release mechanism is varied with the incorporation methods. In this paper, the latest advances in the controlled release of growth factors by blending, hydrogel, microsphere embedding and chemical bonding are reviewed. The potential application of ultrafine fibric embedding in growth factor delivery is described as well.
Wu
Lili
L
School of Material Science and Engineering, Tianjin University, Tianjin 300072, China.
Yuan
Xiaoyan
X
Yao
Kangde
K
D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis; D016503:Drug Delivery Systems / Q000379:methods*; D006133:Growth Substances / Q000493:pharmacokinetics; D020100:Hydrogels; D008863:Microspheres; D023822:Tissue Engineering / Q000379:methods*
D001672:Biocompatible Materials; D006133:Growth Substances; D020100:Hydrogels