title: Renovascular hypertension commencing during fetal life.
abstract: We report three infants with severe, early hypertension due to unilateral renovascular disease, whose cardiovascular changes, or polycythaemia, or both, indicated they had been affected as fetuses. All underwent unilateral nephrectomy, and had a similar histology, with patchy areas having relatively normal glomeruli but immature proximal tubules. This pattern may be a marker for renovascular disease in fetal life.
authors.affiliation: Department of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, UK.
authors.forename: Shivaram
authors.initials: S
authors.lastname: Hegde
authors.forename: Christopher
authors.initials: C
authors.lastname: Wright
authors.forename: Mohan
authors.initials: M
authors.lastname: Shenoy
authors.forename: Nadeem E
authors.initials: NE
authors.lastname: Moghal
authors.forename: Malcolm G
authors.initials: MG
authors.lastname: Coulthard
mesh_terms: D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000196:embryology* / Q000473:pathology / Q000601:surgery; D007231:Infant, Newborn; D007687:Kidney Tubules, Proximal / Q000473:pathology; D008297:Male; D009392:Nephrectomy