Renovascular hypertension commencing during fetal life.
We report three infants with severe, early hypertension due to unilateral renovascular disease, whose cardiovascular changes, or polycythaemia, or both, indicated they had been affected as fetuses. All underwent unilateral nephrectomy, and had a similar histology, with patchy areas having relatively normal glomeruli but immature proximal tubules. This pattern may be a marker for renovascular disease in fetal life.
Hegde
Shivaram
S
Department of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, UK.
Wright
Christopher
C
Shenoy
Mohan
M
Moghal
Nadeem E
NE
Coulthard
Malcolm G
MG
D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000196:embryology* / Q000473:pathology / Q000601:surgery; D007231:Infant, Newborn; D007687:Kidney Tubules, Proximal / Q000473:pathology; D008297:Male; D009392:Nephrectomy