title: Comparing the regulatory behaviour of two cooperative, reversible enzyme mechanisms.
abstract: It is shown that both the reversible Hill equation and a generalised, reversible Monod-Wyman-Changeux equation can give analogous regulatory behaviour when embedded in a model metabolic pathway.
authors.affiliation: Triple-J Group for Molecular Cell Physiology, Department of Biochemistry, University of Stellenbosch, Stellenbosch 7600, South Africa. bgoli@sun.ac.za
authors.forename: B G
authors.initials: BG
authors.lastname: Olivier
authors.forename: J M
authors.initials: JM
authors.lastname: Rohwer
authors.forename: J L
authors.initials: JL
authors.lastname: Snoep
authors.forename: J H S
authors.initials: JH
authors.lastname: Hofmeyr
mesh_terms: D002384:Catalysis; D003067:Coenzymes / Q000737:chemistry*; D003198:Computer Simulation; D004789:Enzyme Activation; D005246:Feedback; D008956:Models, Chemical; D008958:Models, Molecular; D009097:Multienzyme Complexes / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D003067:Coenzymes; D009097:Multienzyme Complexes