title: [Dosimetric consequences of the application of a rectum hull-planning volume for treatment planning of intensity modulated radiotherapy of prostate cancer].
abstract: The present study evaluated a hull-volume definition strategy for the planning organ at risk volume (PRV) for the rectum in the planning of radiotherapy of prostate cancer. The bounding volumes of rectum contours of 1 to 5 CT scans were compared on the basis of the rectum coverage probabilities for 5 patients. In addition, IMRT treatment plans were optimized using the rectum hull PRV5 of 5 CTs and each of the conventional rectum contours PRV1. The plans were compared on the basis of the organ doses caused by the individual organ motion. PRV5 allowed to cover the rectum with a probability of nearly 90% (PRV1 67%). Rectal wall dose showed a great variability for PRV1, while planned and treatment dose agreed well for PRV5 due to the improved geometric information which resulted in a better rectal sparing. In conclusion, the rectum hull-volume PRV5 is a well suited PRV for planning of IMRT dose distributions allowing dose escalation as well as rectal sparing.
authors.affiliation: Medizinische Physik, Klinik für Strahlentherapie, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen. christoph.baum@gmx.de
authors.forename: Christoph
authors.initials: C
authors.lastname: Baum
authors.forename: Markus
authors.initials: M
authors.lastname: Alber
authors.forename: Fridtjof
authors.initials: F
authors.lastname: Nüsslin
mesh_terms: D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D010347:Patient Care Planning; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D012007:Rectum / Q000000981:diagnostic imaging; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed