Role of the endothelium in pulmonary arterial hypertension.
Pulmonary hypertension represents a significant disease burden in both the developed and developing worlds. Certain forms of pulmonary hypertension are more common in some countries than others but people of all races, all ages and both sexes are affected. Treatment options are limited and expensive. The development of new therapies will be determined by improved understanding of endothelial cell biology.
Haworth
S G
SG
Department of Vascular Biology, Institute of Child Health, University College London, London, WC1N 1EH, UK. s.haworth@ich.ucl.ac.uk
D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure; D004730:Endothelium, Vascular / Q000503:physiopathology*; D014943:Global Health; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D015994:Incidence; D011651:Pulmonary Artery / Q000503:physiopathology*
D000959:Antihypertensive Agents