title: Alveolar bone graft for patients with cleft lip/palate using bone particles and titanium mesh: A quantitative study.
abstract: OBJECTIVE
  This study evaluated the bone volume, height, and width that can be obtained in alveolar ridge augmentation using titanium mesh and autogenous bone particles in patients with cleft lip/palate.
  
  
  METHODS
  Subjects were 15 patients with cleft lip/palate requiring tertiary bone graft for implant therapy. Computed tomography (CT) scans were taken before removing the mesh, from 1 to 21 months after bone grafting. Forty-three reconstructed images corresponding to the positions for implant placement were selected for this study. The percent defect filled with bone (%BONE), defined as the percentage of newly formed bone in the space created by the mesh, was measured for image analyses. In linear analyses, 4 parameters were used: increased bone height (IBH), percent increased bone height (%IBH), increased bone width (IBW), and percent increased bone width (%IBW). Factors influencing the quantitative data and the clinical courses of placed implants were also explored.
  
  
  RESULTS
  The average %BONE was 91.1%. IBH averaged 4.4 mm, whereas %IBH averaged 88.5%. IBW averaged 4.6 mm, whereas %IBW averaged 86.4%. Little correlation was present between the quantitative data and patient age, or time interval. A significant correlation was identified between the data for span of the grafted area and %BONE (correlation coefficient value = -0.36). However, the diminishing rate was very low. No implants were lost postoperatively.
  
  
  CONCLUSIONS
  Alveolar ridge augmentation with titanium mesh and autogenous bone particles from the anterior iliac crest has very high predictability as a preimplant procedure in patients with cleft lip/palate.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan. ymatsui@yokohama-cu.ac.jp
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Matsui
authors.forename: Mizuho
authors.initials: M
authors.lastname: Ohta
authors.forename: Kohsuke
authors.initials: K
authors.lastname: Ohno
authors.forename: Masao
authors.initials: M
authors.lastname: Nagumo
mesh_terms: D000293:Adolescent; D000328:Adult; D000539:Alveolar Process / Q000000981:diagnostic imaging; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D002971:Cleft Lip / Q000534:rehabilitation; D002972:Cleft Palate / Q000534:rehabilitation*; D003758:Dental Implantation, Endosseous; D019094:Dental Prosthesis, Implant-Supported; D006801:Humans; D007085:Ilium / Q000601:surgery; D008875:Middle Aged; D013526:Surgical Mesh; D014025:Titanium; D014057:Tomography, X-Ray Computed
chemical_list: D014025:Titanium