title: [Simultaneous determination of pesticides in agricultural products by LC/MS/MS using clean-up with ultrafiltration].
abstract: A method for simultaneous determination of multiple pesticide residues in agricultural products was developed by using a pretreatment with ultrafiltration, followed by liquid chromatography-tandem mass spectrometry (LC/MS/MS). The pretreatment process (extraction of pesticides from agricultural products with methanol, dilution of the extract with water, and ultrafiltration) gave recoveries in the range of 50-150% for 63 of 83 pesticides spiked at 0.25 microg/ g into 6 agricultural products. The detection limits of pesticides by LC/MS/MS were below 0.0005-0.05 micro/g. This method is useful for screening purposes and for multiresidue analysis of pesticides in agricultural products. Pesticide residues in 50 domestic crops were investigated by this method, and residues of 14 pesticides were detected in 30 crops.
authors.affiliation: Research Institute for Environmental Sciences and Public Health of Iwate Prefecture: 1-36-1, Iiokasinden, Morioka 020-0852, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Hatakeyama
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kajita
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Akira
authors.initials: A
authors.lastname: Sasaki
authors.forename: Satoru
authors.initials: S
authors.lastname: Takahashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Komukai
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D018556:Crops, Agricultural / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D014462:Ultrafiltration / Q000379:methods*
chemical_list: D010573:Pesticide Residues