title: Combined 633-nm and 830-nm led treatment of photoaging skin.
abstract: OBJECTIVE
  To evaluate the clinical efficacy and ultrastructural changes in photodamaged skin after combined 633-nm and 830-nm light-emitting diode (LED) treatments.
  
  
  METHODS
  Thirty-six subjects received 9 LED treatments over the course of 5 weeks and were subsequently evaluated for final clinical improvement 12 weeks after treatment. Five subjects were also biopsied to determine the ultrastuctural posttreatment changes in collagen fibers.
  
  
  RESULTS
  A statistically significant improvement in wrinkles was seen after profilometric analysis. The majority of subjects reported improvements in softness, smoothness, and firmness at all time points. Electron microscopic analysis showed evidence of post-LED treatment of thicker collagen fibers.
  
  
  CONCLUSIONS
  633-nm and 830-nm LED treatments play a role in the treatment of photodamaged skin. LED treatments can be used as either a primary or adjunctive treatment modality.
authors.affiliation: Skin Laser and Surgery Specialists of NY/NJ, New York, NY 10022, USA. drdavidgoldberg@skinandlasers.com
authors.forename: David J
authors.initials: DJ
authors.lastname: Goldberg
authors.forename: Snehal
authors.initials: S
authors.lastname: Amin
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Russell
authors.forename: Robert
authors.initials: R
authors.lastname: Phelps
authors.forename: Norma
authors.initials: N
authors.lastname: Kellett
authors.forename: Laurence A
authors.initials: LA
authors.lastname: Reilly
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010789:Phototherapy / Q000379:methods*; D015595:Skin Aging; D012871:Skin Diseases / Q000473:pathology / Q000628:therapy*