title: Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.
abstract: Clinical isolates of Trichomonas vaginalis were obtained from women consecutively enrolled in a study of partner notification. Testing of susceptibility to metronidazole and tinidazole was performed. Resistance to metronidazole and tinidazole was present in 17/178 (9.6%) and 1/178 (0.56%) strains, respectively. In vitro resistance was poorly correlated with clinical response to treatment.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, ZRB 239, 1530 3rd Ave. S., Birmingham, AL 35294-0007, USA. schwebke@uab.edu
authors.forename: Jane R
authors.initials: JR
authors.lastname: Schwebke
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Barrientes
mesh_terms: D000818:Animals; D000994:Antitrichomonal Agents / Q000494:pharmacology*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*; D015995:Prevalence; D014011:Tinidazole / Q000494:pharmacology*; D014246:Trichomonas vaginalis / Q000187:drug effects* / Q000302:isolation & purification*
chemical_list: D000994:Antitrichomonal Agents; D014011:Tinidazole; D008795:Metronidazole