title: Update on drugs used to treat endocrine diseases in small animals.
abstract: Drug therapy for the endocrine system is implemented to replace a hormone deficiency or to prevent or reduce the formation or effects of excess hormone. Treatment of endocrine disorders covers diseases of the pituitary, adrenal, parathyroid, and thyroid glands as well as the endocrine pancreas. This article focuses on new therapies currently available for specific diseases. Administration of trilostane for treatment of hyperadrenocorticism and use of insulin glargine, protamine zinc insulin (PZI), and porcine Lente insulin for diabetes mellitus are discussed. In addition, transdermal methimazole therapy for treatment of feline hyperthyroidism and administration of progestins for pituitary dwarfism are considered.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA. behreen@vetmed.auburn.edu
authors.forename: Ellen N
authors.initials: EN
authors.lastname: Behrend
mesh_terms: D000308:Adrenocortical Hyperfunction / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D013956:Antithyroid Agents / Q000627:therapeutic use; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000662:veterinary*; D013196:Dihydrotestosterone / Q000031:analogs & derivatives / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006980:Hyperthyroidism / Q000188:drug therapy / Q000662:veterinary*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D049528:Insulin, Long-Acting / Q000627:therapeutic use; D008713:Methimazole / Q000627:therapeutic use
chemical_list: D013956:Antithyroid Agents; D004791:Enzyme Inhibitors; D007004:Hypoglycemic Agents; D049528:Insulin, Long-Acting; D013196:Dihydrotestosterone; D008713:Methimazole; C009954:trilostane