Novel and efficient synthesis of iminocoumarins via copper-catalyzed multicomponent reaction.
A variety of substituted iminocoumarins are prepared in good to excellent yields via a copper-catalyzed multicomponenet reaction of sulfonyl azides, terminal alkynes, and salicylaldehydes or o-hydroxylacetophenones. The method is general, mild, versatile, and efficient. A plausible mechanism for the domino process is proposed.
Cui
Sun-Liang
SL
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
Lin
Xu-Feng
XF
Wang
Yan-Guang
YG
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D007097:Imines / Q000737:chemistry*; D008958:Models, Molecular
D003374:Coumarins; D007097:Imines; D003300:Copper