title: Monostotic fibrous dysplasia of the proximal femur and liposclerosing myxofibrous tumor: which one is which?
abstract: Clinical, histological, and genetic studies of two cases of isolated fibro-osseous lesions of the femur in adults show the overlap between monostotic fibrous dysplasia (MFD) of the proximal femur and the so-called liposclerosing myxofibrous tumor. The two cases highlight how the incomplete understanding of the natural history of MFD may result in diagnostic pitfalls or incorrect classification of individual lesions.
authors.affiliation: Dipartimento de Medicina Sperimentale e Patologia, Università La Sapienza, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Corsi
authors.forename: Fernando
authors.initials: F
authors.lastname: De Maio
authors.forename: Ernesto
authors.initials: E
authors.lastname: Ippolito
authors.forename: Natasha
authors.initials: N
authors.lastname: Cherman
authors.forename: Pamela
authors.initials: P
authors.lastname: Gehron Robey
authors.forename: Mara
authors.initials: M
authors.lastname: Riminucci
authors.forename: Paolo
authors.initials: P
authors.lastname: Bianco
mesh_terms: D000328:Adult; D002864:Chromogranins; D003937:Diagnosis, Differential; D005260:Female; D005266:Femoral Neoplasms / Q000145:classification / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D005272:Femur Neck / Q000473:pathology / Q000601:surgery; D005350:Fibroma / Q000145:classification / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D005358:Fibrous Dysplasia, Monostotic / Q000145:classification / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D019205:GTP-Binding Protein alpha Subunits, Gs / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D012150:Polymorphism, Restriction Fragment Length; D012598:Sclerosis
chemical_list: D002864:Chromogranins; C406732:GNAS protein, human; D019205:GTP-Binding Protein alpha Subunits, Gs