Environmental influences on family similarity in afternoon cortisol levels: twin and parent-offspring designs.
Modest genetic effects on morning, but not late-day, cortisol levels have been established. Environmental demands may influence basal cortisol levels later in the day. Thus, we anticipated that individuals in the same family would have similar afternoon cortisol levels to the extent that they share aspects of their environment. We examined afternoon basal cortisol levels measured across 3 consecutive days in mothers and fathers and in multiple offspring in two separate large and longitudinal studies. Study I involved 321 families with singletons while study II involved 233 families with twins. Modest family similarity was apparent for afternoon basal cortisol levels in both studies. Spouses' cortisol levels were also correlated. Data from study II demonstrated that family resemblance in afternoon cortisol was accounted for by underlying shared environmental factors, but not underlying genetic factors. Shared environment accounted for 62% of the variation in twin afternoon basal cortisol levels and 14% of the variation in parent afternoon basal cortisol levels. We used pooled data from the two studies to examine whether parental depression, socioeconomic status (SES), and offspring sex and age impacted cortisol levels. Female offspring had higher cortisol levels than males, and cortisol decreased with age until about 9 years of age, after which cortisol increased with age. Family similarity persisted after accounting for parental depression, SES, time of day, and offspring sex and age, which suggests that the shared family environment influences parent and offspring stress hormone levels throughout the childhood years.
Schreiber
Jane E
JE
Department of Psychology, University of Wisconsin-Madison, 1202 West Johnson Street, Madison, WI 53706, USA. jeschreiber@wisc.edu
Shirtcliff
Elizabeth
E
Van Hulle
Carol
C
Lemery-Chalfant
Kathryn
K
Klein
Marjorie H
MH
Kalin
Ned H
NH
Essex
Marilyn J
MJ
Goldsmith
H Hill
HH
D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm / Q000235:genetics* / Q000502:physiology*; D003863:Depression / Q000378:metabolism*; D004777:Environment; D005190:Family; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D010375:Pedigree; D012016:Reference Values; D012463:Saliva / Q000378:metabolism; D012737:Sex Factors; D013223:Statistics as Topic; D014429:Twins, Dizygotic / Q000378:metabolism; D014430:Twins, Monozygotic / Q000378:metabolism
D006854:Hydrocortisone