Hypothyroidism in a breast-fed preterm infant resulting from maternal topical iodine exposure.
Hypothyroidism developed in a preterm infant, whose initial screening thyroid function test results were normal, at 2 weeks of life. The infant's mother was packing her Caesarian incision with iodine soaked gauze, resulting in a markedly increased breast milk iodine concentration. Treatment with oral L-thyroxine normalized thyroid function tests.
Smith
Vincent C
VC
Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. vsmith1@bidmc.harvard.edu
Svoren
Britta M
BM
Wolfsdorf
Joseph I
JI
D000287:Administration, Topical; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced*; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000139:chemically induced*; D007455:Iodine / Q000008:administration & dosage / Q000009:adverse effects* / Q000032:analysis; D008895:Milk, Human / Q000737:chemistry; D009035:Mothers
D007455:Iodine