Tin-free radical alkylation of ketones via N-silyloxy enamines.
The radical alkylation of ketones is achieved by their conversion into corresponding N-silyloxy enamines, followed by a radical reaction with alkyl halides bearing electron-withdrawing groups.
Song
Hyun-Ji
HJ
Department of Chemistry and Center for Molecular Design and Synthesis, School of Molecular Science (BK-21), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
Lim
Che Jo
CJ
Lee
Sunggi
S
Kim
Sunggak
S