title: Adenoid Cystic Carcinoma of the lacrimal gland metastasising to the liver: report of a case.
abstract: BACKGROUND
  Adenoid Cystic Carcinoma of the lacrimal gland is a rare tumour. Their aggressive behaviour, with a high-risk of local recurrence, and late distant spread of the tumour even after aggressive management has been reported. Metastasis to the liver is rare and when it occurs, it is usually part of widespread metastasis, and therefore surgical treatment is seldom considered.
  
  
  METHODS
  We report a rare case of an isolated liver metastasis from a lacrimal gland adenoid cystic carcinoma 20 years after resection of the primary tumour. The patient presented with right upper quadrant pain radiating to the back and shortness of breath of 3 months duration. No local recurrence was detected during a 15 year follow-up with computerized tomography (CT) of the head. Abdominal CT scan demonstrated a solitary liver tumour with no other primary source, and the bone scan was normal. The patient was treated with an extended right hemihepatectomy. The histology revealed a predominantly cribriform tumour with focal areas of basaloid type metastatic lacrimal gland adenoid cystic carcinoma.
  
  
  CONCLUSIONS
  This case illustrates the unpredictable behaviour of adenoid cystic carcinoma and the need for a life long follow up for these patients after treatment. The possibility of surgical resection for liver metastasis from adenoid cystic carcinoma should always be considered.
authors.affiliation: Hepato Pancreatico Biliary Surgery Unit - Southampton General Hospital, Southampton, SO16 6YD, UK. bashar2000@yahoo.com
authors.forename: Bashar A
authors.initials: BA
authors.lastname: Zeidan
authors.forename: Mohammed
authors.initials: M
authors.lastname: Abu Hilal
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Gholmy
authors.forename: Hanan
authors.initials: H
authors.lastname: El-Mahallawi
authors.forename: Neil W
authors.initials: NW
authors.lastname: Pearce
authors.forename: John N
authors.initials: JN
authors.lastname: Primrose