The responses of growing pigs to a chronic-intermittent stress treatment.
Many of the stressor treatments used in animal models of depression have parallels in the normal experiences of domestic pigs. The experiment described here aimed to assess whether a chronic-intermittent stress regime caused behavioural or physiological changes, indicative of depression, in domestic pigs. Ten juvenile male pigs were exposed to a social and environmental stress regime. Over the stressor period, weight gain was significantly lower in test pigs than in control pigs. Stress treatment had a significant effect on salivary cortisol levels, with test pigs having a higher salivary cortisol concentration than control pigs after the stress treatment but not before. Test pigs showed less ventral lying than control pigs in the post-stress observation. A detrended fluctuation analysis (DFA) of postural behavioural organisation showed that test pigs had a more structured pattern of activity than controls in the post-stress observation and a tendency towards a more structured pattern in the pre-stress observation. There were no major behavioural differences between the two groups during three repeated open field tests. The results suggest that the stressor treatment did create a mild chronic stress, as indicated by the hypercortisolaemia and lower weight gain in the test pigs. However, no unambiguous behavioural indicators of depression were seen. The behavioural analysis did show that fractal techniques, such as DFA, could be applied to pig behaviour and that they can reveal extra novel information about the structure of an individual's behavioural organisation and how it changes in response to complex environmental stressors.
Rutherford
Kenneth M D
KM
Welfare Biology Group, Roslin Institute (Edinburgh), Roslin, Midlothian, EH25 9PS, Scotland, United Kingdom. kenny.rutherford@sas.ac.uk
Haskell
Marie J
MJ
Glasbey
Chris
C
Lawrence
Alistair B
AB
D000308:Adrenocortical Hyperfunction / Q000209:etiology; D000704:Analysis of Variance; D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal / Q000502:physiology*; D001835:Body Weight / Q000502:physiology; D005106:Exploratory Behavior / Q000502:physiology; D006854:Hydrocortisone / Q000378:metabolism; D008297:Male; D012463:Saliva / Q000737:chemistry; D013315:Stress, Psychological / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology*; D013552:Swine; D013997:Time Factors
D006854:Hydrocortisone