4D imaging for target definition in stereotactic radiotherapy for lung cancer.
Stereotactic radiotherapy of Stage I lung tumors has been reported to result in high local control rates that are far superior to those obtained with conventional radiotherapy techniques, and which approach those achieved with primary surgery. Breathing-induced motion of tumor and target tissues is an important issue in this technique and careful attention should be paid to the contouring and the generation of individualized margins. We describe our experience with the use of 4DCT scanning for this group of patients, the use of post-processing tools and the potential benefits of respiratory gating.
Slotman
Ben J
BJ
Department of Radiation Oncology, VU University medical center, Amsterdam, The Netherlands. bj.slotman@vumc.nl
Lagerwaard
Frank J
FJ
Senan
Suresh
S
D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D011857:Radiographic Image Interpretation, Computer-Assisted; D013902:Radiography, Thoracic; D016634:Radiosurgery / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D012119:Respiration; D015656:Respiratory Mechanics; D014057:Tomography, X-Ray Computed / Q000379:methods*; D047368:Tumor Burden