Pitfalls in non-therapeutic research in children.
Research has brought significant medical advances in modern times benefiting virtually all people. Children as a class should not be excluded from research studies. However, non-therapeutic research is potentially problematic in children because they must be afforded special protection from harm and exploitation by care-givers, researchers, and institutional review boards. An article in this month's journal provides an opportunity for a systematic analysis using the methodology provided by the United States Code of Federal Regulations. The research design of this particular study does not appear to stand up to the requirements of the Code.
Mallory
George B
GB
Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030, USA. gbmallor@texaschildrenshospital.org
D001706:Biopsy / Q000941:ethics*; D001980:Bronchi / Q000473:pathology*; D001999:Bronchoscopy; D002648:Child; D003550:Cystic Fibrosis / Q000473:pathology*; D006801:Humans; D033281:Nontherapeutic Human Experimentation / Q000941:ethics* / Q000331:legislation & jurisprudence; D010372:Pediatrics; D018570:Risk Assessment