title: Immunosuppressive therapy protocols in kidney transplantation in adults.
abstract: In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient. A variety of methods are available however, the most frequently used ones have the disadvantage of being immunologicaly non specific. The consequence is a difficult balance between immunosuppression sufficient to prevent the tissue rejection and maintenance of immune system at the level of ability to adequately deal with an infection. The goal, not yet achieved, is to find a way of generating donor specific immunosuppression that leaves the immune machinery otherwise completely intact. The major approaches to immunosuppression are described below.
authors.affiliation: Institute of Clinical Immunology, Sarajevo University Clinics Centre, Sarajevo, Bosnia and Herzegovina.
authors.forename: Jasenko
authors.initials: J
authors.lastname: Karamehić
authors.forename: Marc
authors.initials: M
authors.lastname: Lorber
authors.forename: Richard
authors.initials: R
authors.lastname: Formica
authors.forename: Faris
authors.initials: F
authors.lastname: Gavrankapetanović
authors.forename: Bećir
authors.initials: B
authors.lastname: Heljić
authors.forename: Demo
authors.initials: D
authors.lastname: Subasić
authors.forename: Lamija
authors.initials: L
authors.lastname: Zecević
mesh_terms: D000328:Adult; D006084:Graft Rejection / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation
chemical_list: D007166:Immunosuppressive Agents