title: Laparoscopic splenectomy for isolated parenchymal splenic metastasis of ovarian cancer.
abstract: Metastatic carcinoma of the spleen occurs in a setting of widespread malignant disease. Solitary parenchymal splenic metastasis of ovarian carcinoma is rare. We report a case of a 59-year-old woman who presented with an elevated serum CA125 level due to a solitary splenic metastasis after a long disease-free period. She was treated with laparoscopic splenectomy followed by chemotherapy. The literature contains 16 cases of solitary parenchymal splenic metastasis of ovarian carcinoma. Our case is the third case that was treated with laparoscopic splenectomy. We review the literature, and we focus on the laparoscopic approach in managing these cases.
authors.affiliation: Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Otrock
authors.forename: M A
authors.initials: MA
authors.lastname: Seoud
authors.forename: M J
authors.initials: MJ
authors.lastname: Khalifeh
authors.forename: J A
authors.initials: JA
authors.lastname: Makarem
authors.forename: A I
authors.initials: AI
authors.lastname: Shamseddine
mesh_terms: D018394:CA-125 Antigen / Q000097:blood; D018284:Cystadenocarcinoma, Serous / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000628:therapy; D013154:Spleen / Q000473:pathology / Q000601:surgery; D013160:Splenic Neoplasms / Q000556:secondary* / Q000601:surgery
chemical_list: D018394:CA-125 Antigen