Detection and study of the products of photooxidation of N-retinylidene-N-retinylethanolamine (A2E), the fluorophore of lipofuscin granules from retinal pigment epithelium of human donor eyes.
Yakovleva
M A
MA
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow 119991, Russia.
Sakina
N L
NL
Kononikhin
A S
AS
Feldman
T B
TB
Nikolaev
E N
EN
Dontsov
A E
AE
Ostrovsky
M A
MA
D003624:Darkness; D006801:Humans; D008027:Light; D008062:Lipofuscin / Q000032:analysis / Q000378:metabolism*; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D010777:Photochemistry; D010857:Pigment Epithelium of Eye / Q000737:chemistry / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000737:chemistry; D012176:Retinoids / Q000737:chemistry*; D013481:Superoxides / Q000737:chemistry; D014019:Tissue Donors
C112040:A2-E (N-retinylidene-N-retinylethanolamine); D008062:Lipofuscin; D017382:Reactive Oxygen Species; D012176:Retinoids; D013481:Superoxides; C039316:potassium superoxide