Invasive zygomycosis: update on pathogenesis, clinical manifestations, and management.
Zygomycosis is an increasingly common infection in immunocompromised patients. Advances in the understanding of Zygomycetes pathobiology and the introduction of new drugs with improved activity and tolerability for treatment of zygomycosis have improved the prospects of effectively controlling this devastating infection. Further reductions in mortality will require improved diagnostic and novel therapeutic approaches for this group of aggressive opportunistic molds.
Kontoyiannis
Dimitrios P
DP
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. dkontoyi@mdanderson.org
Lewis
Russell E
RE
D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D020096:Zygomycosis / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics / Q000382:microbiology*
D000935:Antifungal Agents