title: Lower brainstem dysfunction in an infant with persistent primitive trigeminal artery.
abstract: A 6-month-old boy with persistent primitive trigeminal artery (PPTA) presented with stridor, dysphagia, delayed motor development and postural neck and shoulder dystonia. Magnetic resonance imaging/angiography and ultrasonography revealed PPTA, with flow from the dilated basilar artery to the right internal carotid artery, lower brainstem compression by the dilated basilar artery, and cerebellar vermis hypoplasia. Evoked potentials showed lower pons and medulla oblongata functional disruption. These lesions may be related to vascular etiology in the lower brainstem or to congenital malformation syndrome involving infratentorial structures. The relationship of this condition to Möbius syndrome is discussed.
authors.affiliation: Division of Child Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonogo 683-8504, Japan.
authors.forename: Tohru
authors.initials: T
authors.lastname: Okanishi
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Saito
authors.forename: Shiho
authors.initials: S
authors.lastname: Miki
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Nagaishi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hanaki
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tomita
authors.forename: Chisako
authors.initials: C
authors.lastname: Fukuda
authors.forename: Shinya
authors.initials: S
authors.lastname: Fujii
authors.forename: Kazunori
authors.initials: K
authors.lastname: Fujiwara
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kawamoto
authors.forename: Fumiko
authors.initials: F
authors.lastname: Hata
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Maegaki
authors.forename: Kousaku
authors.initials: K
authors.lastname: Ohno
mesh_terms: D000015:Abnormalities, Multiple / Q000503:physiopathology; D001927:Brain Diseases / Q000209:etiology* / Q000503:physiopathology*; D001933:Brain Stem / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D002536:Cerebral Arteries / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D006801:Humans; D007223:Infant; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D014463:Ultrasonography