Effects of radiation damping on Z-spectra.
Radiation damping induced by the strong water magnetization in Z-spectroscopy experiments can be sufficient to perturb significantly the resultant Z-spectrum. With a probe tuned to exact electrical resonance the effects are relatively straightforward, narrowing the central feature of the Z-spectrum. Where, as is commonly the case, the probe is tuned sufficiently well to give optimum signal-to-noise ratio and radiofrequency field strength but is not at exact resonance, radiation damping introduces an unexpected asymmetry into the Z-spectrum. This has the potential to complicate the use of Z-spectrum asymmetry to study chemical exchange, for example in the estimation of pH in vivo.
Williamson
David C
DC
Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
Närväinen
Johanna
J
Hubbard
Penny L
PL
Kauppinen
Risto A
RA
Morris
Gareth A
GA
D016477:Artifacts; D003198:Computer Simulation; D004735:Energy Transfer; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008956:Models, Chemical; D008958:Models, Molecular; D011846:Radio Waves; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014867:Water / Q000032:analysis* / Q000737:chemistry*
D014867:Water