Prenylated phenolics from Ganoderma fornicatum.
Three new prenylated phenolic compounds, fornicins A-C (1-3), were obtained from the fruiting bodies of Ganoderma fornicatum. The structure elucidation was achieved by interpretation of spectroscopic data. These compounds exhibited moderate cytotoxic activity with IC(50) values of 15 to 30 microg/mL in Hep-2 cells.
Niu
Xue-Mei
XM
School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Li
Sheng-Hong
SH
Sun
Han-Dong
HD
Che
Chun-Tao
CT
D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D004354:Drug Screening Assays, Antitumor; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032902:Ganoderma / Q000737:chemistry*; D006801:Humans; D020128:Inhibitory Concentration 50; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000970:Antineoplastic Agents; D005663:Furans; D010636:Phenols; C514410:fornicin A; C514411:fornicin B; C514412:fornicin C