Pyrinadines B-G, new bis-pyridine alkaloids with an azoxy moiety from sponge Cribrochalina sp.
Six new cytotoxic bis-3-alkylpyridine alkaloids with an azoxy moiety, pyrinadines B-G (1-6), have been isolated from an Okinawan marine sponge Cribrochalina sp., and the structures were elucidated by spectroscopic data and chemical means.
Kariya
Yuuko
Y
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Kubota
Takaaki
T
Fromont
Jane
J
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D001391:Azo Compounds / Q000737:chemistry*; D006801:Humans; D007624:KB Cells / Q000187:drug effects; D007939:Leukemia L1210 / Q000188:drug therapy; D051379:Mice; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000470:Alkaloids; D000970:Antineoplastic Agents; D001391:Azo Compounds; D011725:Pyridines; C023666:pyridine