title: Research project: Charleston Bioengineered Kidney Project.
abstract: The goal of Charleston Bioengineered Kidney Project is to engineer a functional living human kidney suitable for surgical implantation using principles of directed tissue self-assembly and tissue fusion. This is a multidisciplinary project which incorporates multiple innovative bioengineering technologies and expertise from a broad spectrum of disciplines. The conceptual framework, engineering principles, design, potential cell source as well as the first preliminary data demonstrating the feasibility of the proposed Charleston Bioengineered Kidney Project are outlined. The potential challenges are described. Finally, the experts' opinion about the proposed project is also presented.
authors.affiliation: Bioprinting Research Center, Medical University of South Carolina, Charleston, SC, USA. mironovv@musc.edu
authors.forename: Vladimir
authors.initials: V
authors.lastname: Mironov
authors.forename: Christopher
authors.initials: C
authors.lastname: Drake
authors.forename: Xuejun
authors.initials: X
authors.lastname: Wen
mesh_terms: D000818:Animals; D021522:Bioartificial Organs; D001672:Biocompatible Materials; D001698:Biomedical Engineering / Q000379:methods; D001709:Biotechnology / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology* / Q000502:physiology*; D013234:Stem Cells / Q000166:cytology; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D001672:Biocompatible Materials