title: Stereoselective synthesis of 2-dienyl-substituted pyrrolidines using an eta4-dienetricarbonyliron complex as the stereodirecting element: Elaboration to the pyrrolizidine skeleton.
abstract: Primary amines react with keto-aldehyde functionality located in the side-chain of an eta4-dienetricarbonyliron complex to provide the corresponding pyrrolidines in excellent diastereoselectivity. Two of the pyrrolidine products, 1i and 1k, have been elaborated into pyrrolizidines using a 1,5-C-H insertion and radical cyclization strategy, respectively.
authors.affiliation: School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
authors.forename: Iwan
authors.initials: I
authors.lastname: Williams
authors.forename: Benson M
authors.initials: BM
authors.lastname: Kariuki
authors.forename: Keith
authors.initials: K
authors.lastname: Reeves
authors.forename: Liam R
authors.initials: LR
authors.lastname: Cox
mesh_terms: D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D011763:Pyrrolizidine Alkaloids / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011759:Pyrrolidines; D011763:Pyrrolizidine Alkaloids