Intrinsic macrolide resistance in rapidly growing mycobacteria.
This study reports the discovery of erm genes in seven species of rapidly growing mycobacteria (RGM): Mycobacterium boenickei, M. goodii, M. houstonense, M. mageritense, M. neworleansense, M. porcinum, and M. wolinskyi. This study further substantiates the role of erm genes in intrinsic macrolide resistance in RGM.
Nash
Kevin A
KA
Department of Pathology, University of Southern California, Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA. kanash@usc.edu
Andini
Nadya
N
Zhang
Yansheng
Y
Brown-Elliott
Barbara A
BA
Wallace
Richard J
RJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D024881:Drug Resistance, Bacterial; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*; D008780:Methyltransferases / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D009161:Mycobacterium / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D017422:Sequence Analysis, DNA
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D018942:Macrolides; D008780:Methyltransferases