Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.
Clinical isolates of Trichomonas vaginalis were obtained from women consecutively enrolled in a study of partner notification. Testing of susceptibility to metronidazole and tinidazole was performed. Resistance to metronidazole and tinidazole was present in 17/178 (9.6%) and 1/178 (0.56%) strains, respectively. In vitro resistance was poorly correlated with clinical response to treatment.
Schwebke
Jane R
JR
Department of Medicine, University of Alabama at Birmingham, ZRB 239, 1530 3rd Ave. S., Birmingham, AL 35294-0007, USA. schwebke@uab.edu
Barrientes
Frank J
FJ
D000818:Animals; D000994:Antitrichomonal Agents / Q000494:pharmacology*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*; D015995:Prevalence; D014011:Tinidazole / Q000494:pharmacology*; D014246:Trichomonas vaginalis / Q000187:drug effects* / Q000302:isolation & purification*
D000994:Antitrichomonal Agents; D014011:Tinidazole; D008795:Metronidazole