title: [Sinus histiocytosis with massive lymphadenopathy].
abstract: OBJECTIVE
  To explore the therapeutic strategy of sinus histiocytosis with massive lymphadenopathy (SHML).
  
  
  METHODS
  The six patients with SHML were treated with different therapeutic strategies.
  
  
  RESULTS
  Two of six patients were treated with radiation therapy and chemical therapy resulting in tumor lessened markedly. The tumor of other four cases disappeared after comprehensive treatment including operation, immunity and interferon therapy.
  
  
  CONCLUSIONS
  The comprehensive therapy, mainly including surgical treatment, is effective for SHML.
authors.affiliation: Department of Otorhinolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China. Liyouzhong196311@yahoo.com
authors.forename: Youzhong
authors.initials: Y
authors.lastname: Li
authors.forename: Yongde
authors.initials: Y
authors.lastname: Lu
authors.forename: Xinming
authors.initials: X
authors.lastname: Yang
authors.forename: Yici
authors.initials: Y
authors.lastname: Zeng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D007376:Interleukin-2 / Q000627:therapeutic use; D008206:Lymphatic Diseases / Q000150:complications / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D055815:Young Adult
chemical_list: D007376:Interleukin-2; D007372:Interferons