Optimization of the dopant for the trace determination of polycyclic aromatic hydrocarbons by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry.
The composition of the dopant for the analysis of polycyclic aromatic hydrocarbons (PAHs) by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry under reversed-phase conditions was optimized to enhance the ionization efficiency for PAHs. The most suitable dopant was a toluene/anisole mixture (99.5:0.5, v/v) and it could improve limit of detections (LODs) to 0.79-168 ng mL(-1) (signal-to-noise (S/N)=3) for 16 common PAHs. The LODs are 3.8-40 times lower than those obtained with toluene alone and are comparable to those obtained using gas chromatography/mass spectrometry.
Itoh
Nobuyasu
N
National Metrology Institute of Japan, NMIJ, National Institute of Advanced Industrial Science and Technology, AIST, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8563, Japan. nobuyasu-itoh@aist.go.jp
Aoyagi
Yoshie
Y
Yarita
Takashi
T
D001274:Atmospheric Pressure; D002853:Chromatography, Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000737:chemistry / Q000145:classification; D015203:Reproducibility of Results
D011084:Polycyclic Aromatic Hydrocarbons