title: Local anesthesia during transrectal ultrasonography-guided prostate biopsy: does it have any effect on sexual function?
abstract: BACKGROUND
  TRUS (Trans Rectal Ultra Sonographic)-guided biopsy of the prostate is the procedure of choice for prostate cancer diagnosis in urological clinical practice. TRUS-guided biopsies are associated with pain and anxiety and may interfere with sexual function and potency. The aim of this study was to evaluate whether local anesthesia during TRUS-guided prostate biopsies has any effect on the sexual behavior of patients and to compare the periprostatic infiltration with lidocaine to simple sonographic gel application in a randomized prospective trial.
  
  
  METHODS
  A total of 62 consecutive patients were included in the study randomized in two groups; Group A (n = 30, control group) and Group B (n = 32, lidocaine infiltration group). Interviews regarding their sexual status were conducted at the time they were informed of the need for biopsy, at the time of biopsy and at two scheduled interviews following the biopsy.
  
  
  RESULTS
  Similar results of sexual dysfunction were observed between the two groups. About 6% of patients experienced some degree of dysfunction in anticipation of biopsy (P > 0.02 between the two groups) that was resolved by the end of the follow-up period. In total, only one Group B patient continued to show sexual dysfunction at the time of the last interview compared to two patients in Group A.
  
  
  CONCLUSIONS
  Local infiltration with lidocaine does not seem to play a role in sexual dysfunction following prostate biopsies. Psychological factors influence patients and the urologist should be ready to inform and reassure both the patient and his family.
authors.affiliation: Department of Urology, Athens University Medical School, Laiko General Hospital, 91 Irinis Stree, 153 41, Agia Paraskevi, Athens, Greece.
authors.forename: Konstantinos G
authors.initials: KG
authors.lastname: Stravodimos
authors.forename: Konstantinos N
authors.initials: KN
authors.lastname: Haritopoulos
authors.forename: Christos
authors.initials: C
authors.lastname: Alamanis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Anastasiou
authors.forename: Constantinos
authors.initials: C
authors.lastname: Constantinides
mesh_terms: D000779:Anesthetics, Local / Q000494:pharmacology*; D001707:Biopsy, Needle; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology*; D008297:Male; D010410:Penile Erection / Q000187:drug effects*; D011446:Prospective Studies; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine