Retinitis pigmentosa and hypogammaglobulinemia.
This report describes a family demonstrating an unusual association of retinitis pigmentosa and hypogammaglobulinemia. The proband in this family suffered from another rare illness, ie, Sertoli cell only syndrome. The incidence of retinitis pigmentosa is 1 in 5,000 and that of common variable immunodeficiency state is 1 in 100,000, making a chance association of these illnesses very unlikely.
Starr
John C
JC
Division of Allergy and Immunology, Department of Pathology, Scott and White, Scott, Sherwood, and Brindley Foundation, The Texas A&M University Health Sciences Center College of Medicine, College Station, TX, USA. jstarr@swmail.sw.org
Brasher
George W
GW
Dominguez
John
J
Rao
Arundhati
A
D000328:Adult; D000361:Agammaglobulinemia / Q000235:genetics*; D017074:Common Variable Immunodeficiency / Q000235:genetics*; D006801:Humans; D007239:Infections; D008223:Lymphoma / Q000473:pathology; D008297:Male; D009845:Oligospermia / Q000235:genetics; D012174:Retinitis Pigmentosa / Q000235:genetics*; D012708:Sertoli Cells; D013577:Syndrome; D013737:Testis / Q000166:cytology*