Sigmoid colonic carcinoma associated with deposited ova of Schistosoma japonicum: a case report.
We report a case of sigmoid colonic carcinoma associated with deposited ova of Schistosoma japonicum. A 57-year old woman presented with a 10-mo history of left lower quadrant abdominal pain and a 2-mo history of bloody stools. She had a significant past medical history of asymptomatic schistosomiasis japonica and constipation. A colonoscopy showed an exophytic fragile neoplasm with an ulcerating surface in the sigmoid colon. During the radical operative procedure, we noted the partially encircling tumor was located in the distal sigmoid colon, and extended into the serosa. Succeeding pathological analysis demonstrated the diagnosis of sigmoid colonic ulcerative tubular adenocarcinoma, and showed deposited ova of Schistosoma japonicum in both tumor lesions and mesenteric lymph nodes. Three days after surgery the patient returned to the normal bowel function with one defecation per day. These findings reveal that deposited schistosome ova play a possible role in the carcinogenesis of colorectal cancer.
Li
Wen-Chang
WC
Department of General Practice, Zhongshan Hospital, Fudan University, Shanghai 200032, China. wenchangli@gmail.com
Pan
Zhi-Gang
ZG
Sun
Yi-Hong
YH
D000230:Adenocarcinoma / Q000469:parasitology* / Q000473:pathology / Q000601:surgery; D000818:Animals; D005260:Female; D006801:Humans; D008875:Middle Aged; D010063:Ovum; D012549:Schistosoma japonicum / Q000472:pathogenicity*; D012554:Schistosomiasis japonica / Q000150:complications* / Q000473:pathology; D012811:Sigmoid Neoplasms / Q000469:parasitology* / Q000473:pathology / Q000601:surgery