title: The semi-permeability of silicone: a saline-filled breast implant with intraluminal and pericapsular Aspergillus flavus.
abstract: Fungal infection of breast implants is a rare complication. Growth of fungi within the lumen of saline-filled implants has previously been demonstrated in laboratory studies, however, clinical infections are rare. We report a case of Aspergillus flavus growth within and around a saline-filled breast implant that was inserted 18 months previously. This was successfully treated with implant removal and wound irrigation. Possible routes of microbial contamination as well as survival mechanisms of organisms within saline-filled implants are discussed. This case re-iterates that the silicone envelope of a saline-filled implant is selectively permeable and we believe this is instrumental in facilitating intraluminal microbial growth. This also emphasises the importance of stringent asepsis when dealing with saline-filled breast implants including avoiding contamination of the saline filling fluid.
authors.affiliation: Department of General Surgery, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK. p.k.wright@ncl.ac.uk
authors.forename: P K
authors.initials: PK
authors.lastname: Wright
authors.forename: C
authors.initials: C
authors.lastname: Raine
authors.forename: M
authors.initials: M
authors.lastname: Ragbir
authors.forename: S
authors.initials: S
authors.lastname: Macfarlane
authors.forename: J
authors.initials: J
authors.lastname: O'donoghue
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis*; D001231:Aspergillus flavus / Q000254:growth & development / Q000302:isolation & purification*; D018427:Breast Implants / Q000382:microbiology*; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects*; D010539:Permeability; D016459:Prosthesis-Related Infections / Q000175:diagnosis*; D020034:Silicone Gels; D012965:Sodium Chloride / Q000737:chemistry
chemical_list: D020034:Silicone Gels; D012965:Sodium Chloride