title: Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS).
abstract: Polymorphous hemangioendotheliomas (PH) are rare and borderline malignant tumors that are among the wide range of vascular tumors. We report here a 13-year-old male presenting with a history of weight loss, opportunistic infections, and lymphadenopathy. He was determined to be HIV positive and to have acquired immunodeficiency syndrome (AIDS). A biopsy of a femoral node was diagnostic of PH. His systemic lymphadenopathy appeared to resolve with anti-retroviral therapy. This tumor should be considered within the differential diagnoses of pediatric and immunocompromised patients.
authors.affiliation: Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania, USA. stephan.paul@tuhs.temple.edu
authors.forename: Stephan R
authors.initials: SR
authors.lastname: Paul
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Hurford
authors.forename: Markku M
authors.initials: MM
authors.lastname: Miettinen
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Aronoff
authors.forename: Michael
authors.initials: M
authors.lastname: Delvecchio
authors.forename: Harsh
authors.initials: H
authors.lastname: Grewal
authors.forename: Madalina
authors.initials: M
authors.lastname: Tuluc
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000209:etiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000293:Adolescent; D023241:Antiretroviral Therapy, Highly Active; D017963:Azithromycin / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D006390:Hemangioendothelioma / Q000209:etiology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D015431:Weight Loss
chemical_list: D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D017963:Azithromycin