title: [Laryngeal cancer risk factors].
abstract: Laryngeal cancer is the most common of head and neck cancers. Neoplasm used to develop basing on DNA mutation which leads to uncontrolled growth and cells' division. It is due to spontaneous mutations or influence of chemical, biological and physical factors. Laryngeal cancer generation is conditioned by many synergic factors. Some of them certainly participate in cancer genesis and this thesis is accepted by medical environment and other of them have been discussed giving different information. Definition of the risk factors role in laryngeal cancer etiology is very difficult especially regarding their contemporary occurrence in one person. Most common risk factors are environmental factors, gastroesophageal reflux, viral infections, diet, radiation, individual predisposition. Some of them, such as cigarette smoking and abuse alcohol are significantly oftener confirmed in patients with neoplasm diagnosis and others' role in developing of illness has been still researched. Thus the purpose of the study was to present so far achievements in laryngeal cancer etiology and to emphasize controversies relating to some factors' role in cancer genesis.
authors.affiliation: Wojskowy Instytut Medyczny w Warszawie, Klinika Otolaryngologii CSK MON. djurkiewicz@lekarz.net
authors.forename: Dariusz
authors.initials: D
authors.lastname: Jurkiewicz
authors.forename: Karolina
authors.initials: K
authors.lastname: Dzaman
authors.forename: Piotr
authors.initials: P
authors.lastname: Rapiejko
mesh_terms: D000428:Alcohol Drinking / Q000453:epidemiology*; D002277:Carcinoma / Q000453:epidemiology*; D015984:Causality; D015897:Comorbidity; D005764:Gastroesophageal Reflux / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D016273:Occupational Exposure / Q000706:statistics & numerical data; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*