title: Impact of bariatric surgery on cardiovascular and musculoskeletal morbidity.
abstract: BACKGROUND
  Obesity is currently recognized as a global epidemic. According to recent statistics, the prevalence of obesity increased from 13.8% of the Canadian population in 1978-1979 to 23.1% in 2004, and the prevalence of morbid obesity increased from .9% in 1978-1979 to 2.7% in 2004. Obesity is a known risk factor for highly prevalent chronic diseases, including cardiovascular and musculoskeletal disorders. The objective of the study was to assess the impact of bariatric surgery on cardiovascular and musculoskeletal morbidity.
  
  
  METHODS
  This was an observational study that compared a cohort of 1035 morbidly obese patients treated with bariatric surgery at the Centre for Bariatric Surgery, McGill University Health Centre with a matched cohort of 5746 morbidly obese nonsurgically treated controls. Data were obtained from the Quebec provincial health insurance database (Régie de l'Assurance Maladie du Québec). Morbidity indicators included diagnoses or treatment for cardiovascular or musculoskeletal disorders.
  
  
  RESULTS
  Patients who underwent bariatric surgery had a significant 62% mean reduction in excess weight and 32% mean reduction in body mass index (P < .001). Compared with the matched controls, patients who had undergone bariatric surgery had significantly lower rates of diagnoses and treatments related to cardiovascular and musculoskeletal conditions.
  
  
  CONCLUSIONS
  These results indicate that bariatric surgery is effective in reducing weight and significantly reduces the risk of cardiovascular and musculoskeletal morbidity.
authors.affiliation: Department of Surgery, McGill University Health Centre, Montreal, Quebec, Canada. jsampalis@jssresearch.com
authors.forename: John S
authors.initials: JS
authors.lastname: Sampalis
authors.forename: Fotini
authors.initials: F
authors.lastname: Sampalis
authors.forename: Nicolas
authors.initials: N
authors.lastname: Christou
mesh_terms: D050110:Bariatric Surgery; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009140:Musculoskeletal Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D009767:Obesity, Morbid / Q000150:complications* / Q000453:epidemiology / Q000601:surgery*; D015995:Prevalence; D011792:Quebec / Q000453:epidemiology; D012307:Risk Factors