title: Chronic osteomyelitis of clavicle as primary manifestation of SAPHO syndrome in adolescents: report of four cases and long-term evolution.
abstract: Four cases of chronic osteomyelitis of clavicle as primary manifestation of synovitis, acne, pustulosis, hyperostosis, osteomyelitis (SAPHO) are reported in adolescents. In all cases a typical radiographical evolution had been observed with progressive slow migration of sclerotic area from medial to lateral side of clavicle. Long-term evolution was alternation of remission and exacerbation but none of the patients healed.
authors.affiliation: Department of Orthopaedic Surgery, Saint-Luc University Hospital, Cliniques Saint-Luc, Universite Catholique de Louvain, 10, avenue Hippocrate, 1200 Brussels, Belgium. Pierre-Louis.Docquier@clin.ucl.ac.be
authors.forename: Pierre-Louis
authors.initials: PL
authors.lastname: Docquier
authors.forename: Jacques
authors.initials: J
authors.lastname: Malghem
authors.forename: Maryline
authors.initials: M
authors.lastname: Mousny
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Rombouts
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000150:complications* / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D002648:Child; D002908:Chronic Disease; D002968:Clavicle / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000209:etiology* / Q000473:pathology*; D012598:Sclerosis