title: Learning effect of short-wavelength automated perimetry in patients with ocular hypertension.
abstract: OBJECTIVE
  To evaluate the learning effect of short-wavelength automated perimetry (SWAP) on a group of patients with ocular hypertension experienced with standard automated perimetry (SAP).
  
  
  METHODS
  Thirty patients with ocular hypertension underwent 5 full-threshold SWAP tests at intervals of 7+/-2 days. The parameters investigated to detect a learning effect were duration, the perimetric indices, and the number of points with a P of <5% and 1% in the total and pattern deviation maps. Differences in learning effect were also evaluated by comparing the sensitivities of central, paracentral, and peripheral areas, hemifields and quadrants.
  
  
  RESULTS
  Learning effects were demonstrated for mean defect (P<0.0001, analysis of variance), duration (P=0.0001), the number of points with P<5% in the pattern deviation map (P=0.003), and short fluctuations (P=0.03). The effect was greater in the peripheral than in central areas (P=0.04). Mean defect was the most sensitive parameter, for which the learning effect was statistically significant between the first and the fifth test.
  
  
  CONCLUSIONS
  The results of this study demonstrate a significant learning effect at full-threshold SWAP. This may limit the efficacy of this kind of perimetry in detecting early glaucoma, and should therefore be carefully considered when creating normative databases for new SWAP strategies.
authors.affiliation: Eye Clinic, Department of Medicine, Surgery and Odontoiatry, University of Milan, San Paolo Hospital, Milan, Italy. lucamrossetti@libero.it
authors.forename: Luca
authors.initials: L
authors.lastname: Rossetti
authors.forename: Paolo
authors.initials: P
authors.lastname: Fogagnolo
authors.forename: Stefano
authors.initials: S
authors.lastname: Miglior
authors.forename: Marco
authors.initials: M
authors.lastname: Centofanti
authors.forename: Michele
authors.initials: M
authors.lastname: Vetrugno
authors.forename: Nicola
authors.initials: N
authors.lastname: Orzalesi
mesh_terms: D005260:Female; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D007858:Learning / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis*; D014786:Vision Disorders / Q000175:diagnosis*; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields