title: Integrons containing the VIM-2 metallo-beta-lactamase gene among imipenem-resistant Pseudomonas aeruginosa strains from different Chinese hospitals.
abstract: A total of 140 nonrepetitive strains of imipenem-resistant Pseudomonas aeruginosa were isolated from five different Chinese hospitals. Fourteen isolates were confirmed to contain the VIM-2 metallo-beta-lactamase gene. Twelve isolates harbored two kinds of class 1 integron, containing both VIM-2- and aminoglycoside-resistant genes.
authors.affiliation: Infectious Disease Department, The 1st Affiliated Hospital, Medical School, Zhejiang University, The Key Laboratory of the Infectious Diseases of Public Health Ministry, Hangzhou, Zhejiang, China.
authors.forename: Yun-Song
authors.initials: YS
authors.lastname: Yu
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Qu
authors.forename: Jian-Ying
authors.initials: JY
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Hong-Yang
authors.initials: HY
authors.lastname: Li
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Walsh
mesh_terms: D003227:Conjugation, Genetic; D004251:DNA Transposable Elements; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D015378:Imipenem / Q000494:pharmacology*; D032023:Integrons; D016133:Polymerase Chain Reaction; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D015378:Imipenem; C425108:beta-lactamase bla(vim-2); D001618:beta-Lactamases