Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS).
Polymorphous hemangioendotheliomas (PH) are rare and borderline malignant tumors that are among the wide range of vascular tumors. We report here a 13-year-old male presenting with a history of weight loss, opportunistic infections, and lymphadenopathy. He was determined to be HIV positive and to have acquired immunodeficiency syndrome (AIDS). A biopsy of a femoral node was diagnostic of PH. His systemic lymphadenopathy appeared to resolve with anti-retroviral therapy. This tumor should be considered within the differential diagnoses of pediatric and immunocompromised patients.
Paul
Stephan R
SR
Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania, USA. stephan.paul@tuhs.temple.edu
Hurford
Matthew T
MT
Miettinen
Markku M
MM
Aronoff
Stephen C
SC
Delvecchio
Michael
M
Grewal
Harsh
H
Tuluc
Madalina
M
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000209:etiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000293:Adolescent; D023241:Antiretroviral Therapy, Highly Active; D017963:Azithromycin / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D006390:Hemangioendothelioma / Q000209:etiology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D015431:Weight Loss
D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D017963:Azithromycin