title: Infective endocarditis of native valve after anterior nasal packing.
abstract: We present a case report of a patient who was previously treated for spontaneous epistaxis with a petroleum jelly gauze (0.5 in x 72 in) anterior nasal packing filled with an antibiotic ointment, along with prophylactic oral clindamycin. The patient presented with fever and hypotension 3 days after the nasal packing. Her blood cultures grew methicillin-resistant Staphylococcus aureus and the transesophageal echocardiography showed vegetation on the atrial surface of the posterior mitral valve leaflet, confirming the diagnosis of bacterial endocarditis attributable to nasal packing. Several case reports discuss toxic shock syndrome after nasal packing, but none describe endocarditis of the native heart valves subsequent to anterior nasal packing. Current guidelines on endocarditis prophylaxis produced by the American Heart Association, European Cardiac Society, and British Cardiac Society together with published evidence do not recommend endocarditis prophylaxis for patients with native heart valves undergoing anterior nasal packing.
authors.affiliation: Department of Medicine, Coney Island Hospital, Maimonides Medical Center, Brooklyn, NY 11235, USA. suriyakbrsj@yahoo.com
authors.forename: Suriya
authors.initials: S
authors.lastname: Jayawardena
authors.forename: Jacob
authors.initials: J
authors.lastname: Eisdorfer
authors.forename: Shalaka
authors.initials: S
authors.lastname: Indulkar
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zarkaria
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001458:Bandages / Q000009:adverse effects*; D004697:Endocarditis, Bacterial / Q000209:etiology* / Q000382:microbiology*; D004844:Epistaxis / Q000150:complications* / Q000628:therapy*; D005260:Female; D006349:Heart Valve Diseases / Q000209:etiology* / Q000382:microbiology*; D006801:Humans; D016106:Methicillin Resistance; D009296:Nasal Cavity; D013203:Staphylococcal Infections / Q000209:etiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin