title: Asymmetric hydrogenation with antibody-achiral rhodium complex.
abstract: Monoclonal antibodies have been elicited against an achiral rhodium complex and this complex was used in the presence of a resultant antibody, 1G8, for the catalytic hydrogenation of 2-acetamidoacrylic acid to produce N-acetyl-L-alanine in high (>98%) enantiomeric excess.
authors.affiliation: Department of Macromolecular Science, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: Tohko
authors.initials: T
authors.lastname: Hirano
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kiminami
authors.forename: Daisuke
authors.initials: D
authors.lastname: Taura
authors.forename: Akira
authors.initials: A
authors.lastname: Harada
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000906:Antibodies / Q000737:chemistry*; D002384:Catalysis; D006241:Haptens / Q000737:chemistry; D006865:Hydrogenation; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D000906:Antibodies; D006241:Haptens; D012238:Rhodium