Prevalence of age-related maculopathy in the adult population in China: the Beijing eye study.
OBJECTIVE
To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China.


METHODS
Population-based prevalence study.


METHODS
The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System.


RESULTS
Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, <20/60 and > or =20/400) or blindness (visual acuity <20/400) in one subject (0.023%).


CONCLUSIONS
Visual impairment due to ARM was relatively uncommon in the adult Chinese population in rural and urban regions.
Li
Yibin
Y
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital University of Medical Science, Beijing, China.
Xu
Liang
L
Jonas
Jost B
JB
Yang
Hua
H
Ma
Yingnan
Y
Li
Jianjun
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000706:statistics & numerical data; D001766:Blindness / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010781:Photography; D015995:Prevalence; D012424:Rural Population / Q000706:statistics & numerical data; D014505:Urban Population / Q000706:statistics & numerical data; D015354:Vision, Low / Q000453:epidemiology; D019987:Persons with Visual Disabilities / Q000706:statistics & numerical data