Residual fatigue is independent of antecedent events and disease severity in Guillain-Barré syndrome.
The occurrence of severe fatigue after Guillain-Barré syndrome (GBS), and its relation with disease course, clinical characteristics, and antecedent infections was studied in 100 GBS patients. Severe fatigue, expressed as a mean Fatigue Severity Scale (FSS) score of 5.0 or more, was present in 60% of all patients. It was more frequently present in females and in patients over 50 years (p < 0.01). There was no significant relationship between fatigue severity and the level of functional disability at nadir, antecedent events or infections, clinical variables, and time to follow-up after GBS.
Garssen
M P J
MP
Department of Neurology, Erasmus University Medical Center Rotterdam, PO BOX 1738, 3000 Rotterdam, DR, The Netherlands. m.garssen@erasmusmc.nl
Van Koningsveld
R
R
Van Doorn
P A
PA
D000328:Adult; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D018450:Disease Progression; D005221:Fatigue / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012720:Severity of Illness Index; D013997:Time Factors