title: Ginkgo nut intoxication in a 2-year-old male.
abstract: This report describes a case of ginkgo nut intoxication in a 2-year-old male. The patient presented with vomiting and afebrile convulsion 4 hours after eating a large number of roasted gingko nuts. There was a large volume of ginkgo nuts in his vomited matter, and on admission the concentrations of 4-O-methoxypyridoxine in his serum and urine were elevated. The patient was diagnosed as having ginkgo nut intoxication, and diazepam and pyridoxal phosphate were administered intravenously. After the treatment, his symptoms were resolved. The neurotoxicity of ginkgo nuts should be recognized by pediatricians and parents who have infants.
authors.affiliation: Department of Allergy, Yamaguchi University, School of Medicine, and Department of Hospital Pharmacy, Niigata City General Hospital, Japan.
authors.forename: Shunji
authors.initials: S
authors.lastname: Hasegawa
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Oda
authors.forename: Takashi
authors.initials: T
authors.lastname: Ichiyama
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Hori
authors.forename: Susumu
authors.initials: S
authors.lastname: Furukawa
mesh_terms: D002675:Child, Preschool; D003975:Diazepam / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D005500:Follow-Up Studies; D005517:Foodborne Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D020441:Ginkgo biloba / Q000506:poisoning*; D006801:Humans; D007262:Infusions, Intravenous; D007564:Japan; D008297:Male; D009754:Nuts / Q000506:poisoning*; D017286:Polysomnography; D011732:Pyridoxal Phosphate / Q000008:administration & dosage; D011736:Pyridoxine / Q000031:analogs & derivatives / Q000097:blood / Q000506:poisoning
chemical_list: C001737:4-methoxymethylpyridoxine; D011732:Pyridoxal Phosphate; D011736:Pyridoxine; D003975:Diazepam