title: Plasmodium falciparum malaria associated with mefloquine failure in Gambia.
abstract: A 25-year-old Caucasian man developed Plasmodium falciparum malaria after traveling to Gambia, despite having received chemoprophylaxis with mefloquine. The patient was hospitalized after returning to the United States. He received a 3-day course of atovaquone-proguanil and made a complete recovery. This case illustrates the potential role of pharmacists in the pharmaceutical care of travelers and underscores the importance of using current recommendations for preventing and treating malaria.
authors.affiliation: Department of Pharmacy Practice, College of Pharmacy, Southwestern Oklahoma State University, Weatherford, Oklahoma 73103, USA.
authors.forename: Erin C
authors.initials: EC
authors.lastname: Callen
authors.forename: Chelsea O
authors.initials: CO
authors.lastname: Church
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D053626:Atovaquone / Q000627:therapeutic use; D018890:Chemoprevention; D005714:Gambia; D006801:Humans; D008288:Malaria / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D015767:Mefloquine / Q000494:pharmacology / Q000627:therapeutic use*; D010963:Plasmodium falciparum; D002727:Proguanil / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors; D014195:Travel; D017211:Treatment Failure; D014481:United States
chemical_list: D000962:Antimalarials; D002727:Proguanil; D015767:Mefloquine; D053626:Atovaquone