[Immunoglobulin e and allergen-specific IgE antibodies in cosmonauts before and after long-duration missions on the International Space Station].
Immunoglobulins (IgG, IgA, IgM, IgE), specific IgE-antibodies, and interleukin-4 (IL-4) were investigated in blood serum of nine cosmonauts before and after 128- to 195-day ISS missions. It was shown that long-duration space flight does not change significantly the content of serum immunoglobulins, allergen-specific IgE-antibodies or IL-4. Analysis for probable ratios of the total IgE and IL-4 contents in the pre- and post-flight periods did not reveal any linear correlation of these parameters.
Rykova
M P
MP
Gertsik
Iu G
IuG
Antropova
E N
EN
Buravkova
L B
LB
D000222:Adaptation, Physiological / Q000502:physiology*; D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D018480:Astronauts; D015415:Biomarkers / Q000097:blood; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology*; D015847:Interleukin-4 / Q000097:blood; D007391:International Cooperation; D013026:Space Flight; D018531:Spacecraft; D013997:Time Factors
D000888:Antibodies, Anti-Idiotypic; D015415:Biomarkers; D015847:Interleukin-4; D007073:Immunoglobulin E