title: Adult-to-adult right lobe living donor liver transplantation: comparison of endoscopic retrograde cholangiography with standard T2-weighted magnetic resonance cholangiography for evaluation of donor biliary anatomy.
abstract: OBJECTIVE
  To compare the value of endoscopic retrograde cholangiography (ERC) and standard T2-weighted magnetic resonance cholangiography (MRC) in the evaluation process as adult-to-adult right lobe living donor liver transplantation (LDLTx) demands a successful outcome, and exact knowledge of the biliary tree is implicated to avoid biliary complications, postoperatively.
  
  
  METHODS
  After starting the LDLTx program, 18 liver transplant candidates were selected for LDLTx by a stepwise evaluation process. ERC and standard T2-weighted MRC were performed to evaluate the biliary system of the donor liver. The anatomical findings of ERC and MRC mapping were compared using the Ohkubo classification.
  
  
  RESULTS
  ERC allowed mapping of the whole biliary system in 15/15 (100%) cases, including 14/15 (93.3%) with biliary variants while routine MRC was only accurate in 2/13 (15.4%) cases. MRC was limited in depicting the biliary system proximal of the hepatic bifurcation. Postoperative biliary complications occurred in 2 donors and 8 recipients. Biliary complications were associated with Ohkubo type C, E or G in 6/8 recipients, and 2/3 recipients with biliary leak received a graft with multiple (>=2) bile ducts.
  
  
  CONCLUSIONS
  Pretransplant ERC is safe and superior over standard MRC for detection of biliary variations that occur with a high frequency. However, precise knowledge of biliary variants did not reduce the incidence of postoperative biliary complications.
authors.affiliation: HC Klinik fur Gastroenterologie und Endokrinologie, Innere Medizin, Georg-August-Universitat, Robert-Koch-Strasse 40, D-37075 Gottingen, Germany. gramado@med.uni-goettingen.de
authors.forename: Perdita
authors.initials: P
authors.lastname: Wietzke-Braun
authors.forename: Felix
authors.initials: F
authors.lastname: Braun
authors.forename: Dieter
authors.initials: D
authors.lastname: Muller
authors.forename: Thomas
authors.initials: T
authors.lastname: Lorf
authors.forename: Burckhardt
authors.initials: B
authors.lastname: Ringe
authors.forename: Giuliano
authors.initials: G
authors.lastname: Ramadori
mesh_terms: D000328:Adult; D001659:Biliary Tract / Q000002:abnormalities / Q000033:anatomy & histology*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D046148:Donor Selection; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control