title: Palladium-catalyzed alkylation of sp2 and sp3 C-H bonds with methylboroxine and alkylboronic acids: two distinct C-H activation pathways.
abstract: Palladium-catalyzed alkylations of sp2 and sp3 C-H bonds with either methylboroxine or alkylboronic acids were developed. Ag2O or AgCO3 is used as a crucial oxidant and promoter for the transmetalation step. Ether, ester, alcohol, and alkene functional groups are tolerated. A new C-H activation pathway differing from the cyclometalation process is elucidated using methylboroxine as the coupling partner.
authors.affiliation: Department of Chemistry MS015, Brandeis University, Waltham, MA 02454-9110, USA.
authors.forename: Xiao
authors.initials: X
authors.lastname: Chen
authors.forename: Charles E
authors.initials: CE
authors.lastname: Goodhue
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu