Postural control, gait, and dopamine functions in parkinsonian movement disorders.
Balance impairments and falls, which are common in patients who have parkinsonian movement disorders, are a serious threat to the health of these individuals. However, the underlying mechanisms cannot be fully explained by presynaptic dopaminergic denervation, because balance impairment is at least responsive to L-dopa therapy. This article reviews the latest clinically relevant literature relating postural control, gait, and dopamine in patients who have parkinsonian movement disorders.
Bohnen
Nicolaas I
NI
Department of Radiology and Neurology, University of Michigan, 24 Frank Lloyd Wright Drive, Box 362, Ann Arbor, MI 48106, USA. nbohnen@umich.edu
Cham
Rakié
R
D004298:Dopamine / Q000502:physiology*; D015259:Dopamine Agents / Q000627:therapeutic use; D020233:Gait Disorders, Neurologic / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D004856:Postural Balance / Q000502:physiology*; D012678:Sensation Disorders / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
D015259:Dopamine Agents; D004298:Dopamine