title: Cerebral malaria in spite of peripheral parasite clearance in a patient treated with atovaquone/proguanil.
abstract: Cerebral malaria, the most frequent complication of falciparum malaria, is usually predicted by an increased count of asexual parasites in peripheral blood. We report a case of a female returnee from Ghana who developed cerebral malaria in spite of parasite clearance in peripheral blood after therapy with atovaquone/proguanil.
authors.affiliation: Clinics for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Koch
authors.forename: Klaus
authors.initials: K
authors.lastname: Göbels
authors.forename: Joachim
authors.initials: J
authors.lastname: Richter
authors.forename: Mark
authors.initials: M
authors.lastname: Oette
authors.forename: Dieter
authors.initials: D
authors.lastname: Häussinger
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D037621:Artemisinins / Q000627:therapeutic use; D000077332:Artesunate; D053626:Atovaquone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016779:Malaria, Cerebral / Q000188:drug therapy* / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000302:isolation & purification; D002727:Proguanil / Q000627:therapeutic use*; D011803:Quinine / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000627:therapeutic use
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D012717:Sesquiterpenes; D000077332:Artesunate; D011803:Quinine; D002727:Proguanil; D053626:Atovaquone