title: Stereoselective synthesis of functionalized pyrrolidines via a [3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-Bis(silyl)propenes.
abstract: An efficient protocol for stereoselective synthesis of densely functionalized pyrrolidines by a [3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-bis(silyl)propenes is described.
authors.affiliation: Organic Chemistry and Inorganic Chemistry, KTH Chemical Science and Engineering, 100 44 Stockholm, Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Restorp
authors.forename: Andreas
authors.initials: A
authors.lastname: Fischer
authors.forename: Peter
authors.initials: P
authors.lastname: Somfai
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D003500:Cyclization; D008968:Molecular Conformation; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000475:Alkenes; D000588:Amines; D011759:Pyrrolidines; D012821:Silanes; C013658:propylene