title: Periodontal disease and systemic conditions: a bidirectional relationship.
abstract: For decades, physicians and dentists have paid close attention to their own respective fields, specializing in medicine pertaining to the body and the oral cavity, respectively. However, recent findings have strongly suggested that oral health may be indicative of systemic health. Currently, this gap between allopathic medicine and dental medicine is quickly closing, due to significant findings supporting the association between periodontal disease and systemic conditions such as cardiovascular disease, type 2 diabetes mellitus, adverse pregnancy outcomes, and osteoporosis. Significant effort has brought numerous advances in revealing the etiological and pathological links between this chronic inflammatory dental disease and these other conditions. Therefore, there is reason to hope that the strong evidence from these studies may guide researchers towards greatly improved treatment of periodontal infection that would also ameliorate these systemic illnesses. Hence, researchers must continue not only to uncover more information about the correlations between periodontal and systemic diseases but also to focus on positive associations that may result from treating periodontal disease as a means of ameliorating systemic diseases.
authors.affiliation: Boston University Goldman School of Dental Medicine, Department of Periodontology and Oral Biology, Boston, MA, USA.
authors.forename: Jemin
authors.initials: J
authors.lastname: Kim
authors.forename: Salomon
authors.initials: S
authors.lastname: Amar
mesh_terms: D002097:C-Reactive Protein / Q000502:physiology; D002318:Cardiovascular Diseases / Q000150:complications / Q000378:metabolism / Q000382:microbiology; D048909:Diabetes Complications / Q000378:metabolism / Q000382:microbiology; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D018836:Inflammation Mediators / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D010024:Osteoporosis / Q000150:complications / Q000378:metabolism; D010510:Periodontal Diseases / Q000150:complications* / Q000382:microbiology; D011247:Pregnancy; D047928:Premature Birth / Q000209:etiology / Q000382:microbiology
chemical_list: D018836:Inflammation Mediators; D009569:Nitric Oxide; D002097:C-Reactive Protein