title: Accelerated fracture healing.
abstract: Acceleration of the fracture healing process would have far-reaching benefits for both civilians and military personnel. Decreasing the time to return to complete function would reduce medical costs, enhance quality of life by decreasing pain and increasing mobility, accelerate the return of professional athletes to their sport, and decrease the time for military recruits to enter active duty after injuries incurred in basic training. Moreover, augmenting the healing process may prevent the long-term disability caused by fracture nonunion. Currently available pharmaceutical agents may allow us to realize this goal. However, these agents need to be tested in prospective randomized clinical trials.
authors.affiliation: Department of Orthopaedics, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA.
authors.forename: J Edward
authors.initials: JE
authors.lastname: Puzas
authors.forename: Jeff
authors.initials: J
authors.lastname: Houck
authors.forename: Susan V
authors.initials: SV
authors.lastname: Bukata
mesh_terms: D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D017102:Fracture Healing; D050723:Fractures, Bone / Q000628:therapy*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D010281:Parathyroid Hormone / Q000627:therapeutic use
chemical_list: D050071:Bone Density Conservation Agents; D010281:Parathyroid Hormone