title: Brief cognitive assessment of cancer patients: evaluation of the Mini-Mental State Examination (MMSE) psychometric properties.
abstract: OBJECTIVE
  The aim of the present study was to validate the Greek version of the MMSE in advanced-cancer patients attending a palliative care unit.
  
  
  METHODS
  The sample consisted of 103 advanced-cancer patients. The questionnaire was completed at baseline and three days later. Together with the MMSE, the patients also completed the EORTC QLQ-C30 Cognitive functioning scale, while researchers recorded data on demographic characteristics, disease status and treatment regimen.
  
  
  RESULTS
  MMSE had overall Cronbach alpha 0.890. Validity as performed using known-group analysis showed good results. MMSE discriminated well between subgroups of patients differing in disease severity as defined by ECOG performance status. Comparison between the MMSE and the EORTC Cognitive functioning scale was statistically significant (p<0.05).
  
  
  CONCLUSIONS
  These psychometric properties of the Greek version of the MMSE confirm it as a valid and reliable measure when administered to patients with advanced cancer.
authors.affiliation: Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, University of Athens, 27 Korinthias Street, 115 26 Athens, Greece. mistakidou@yahoo.com
authors.forename: Kyriaki
authors.initials: K
authors.lastname: Mystakidou
authors.forename: Eleni
authors.initials: E
authors.lastname: Tsilika
authors.forename: Efi
authors.initials: E
authors.lastname: Parpa
authors.forename: Antonis
authors.initials: A
authors.lastname: Galanos
authors.forename: Lambros
authors.initials: L
authors.lastname: Vlahos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000453:epidemiology*; D009483:Neuropsychological Tests; D011594:Psychometrics / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012720:Severity of Illness Index