title: Peroperative Gastrograffin bowel lavage in gastroschisis.
abstract: OBJECTIVE
  The aim of the study was to evaluate potential benefits in the use of peroperative bowel lavage with Gastrograffin in neonates with gastroschisis.
  
  
  METHODS
  A retrospective analysis of newborns with gastroschisis was performed over a 10-year period in 2 centers in the United Kingdom. Two groups were studied wherein one had peroperative bowel lavage with Gastrograffin and the other did not.
  
  
  RESULTS
  Data were collected on 116 patients of whom 93 were suitable for analysis. There were no statistically significant differences in primary closure rate, duration of ventilation, parenteral nutrition, or hospital stay. Intestinal obstruction occurred more frequently in the nonlavage group.
  
  
  CONCLUSIONS
  Gastrograffin lavage peroperatively in gastroschisis offers no potential advantage in reducing ventilatory requirements, parenteral nutrition, and hospital stay. It also does not achieve greater primary closure rates, but may reduce the incidence of intestinal obstruction.
authors.affiliation: Department of Paediatric Surgery, Queen's Medical Centre, Nottingham NG72UH, UK.
authors.forename: Abraham
authors.initials: A
authors.lastname: Cherian
authors.forename: Ruth M
authors.initials: RM
authors.lastname: Hallows
authors.forename: Shalinder J
authors.initials: SJ
authors.lastname: Singh
authors.forename: William A
authors.initials: WA
authors.lastname: McCallion
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Stewart
mesh_terms: D003974:Diatrizoate Meglumine / Q000627:therapeutic use*; D013505:Digestive System Surgical Procedures; D005260:Female; D020139:Gastroschisis / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007422:Intestines; D007902:Length of Stay; D008297:Male; D010288:Parenteral Nutrition; D011300:Preoperative Care; D012121:Respiration, Artificial; D012189:Retrospective Studies; D007507:Therapeutic Irrigation / Q000592:standards*
chemical_list: D003974:Diatrizoate Meglumine