title: Real-time imaging of transscleral diode laser cyclophotocoagulation by optical coherence tomography.
abstract: OBJECTIVE
  To present optical coherence tomography (OCT) for real-time imaging of cyclophotocoagulation effects.
  
  
  METHODS
  In a pilot study, real-time transscleral OCT images were generated during diode laser cyclophotocoagulation in four eyes of four patients suffering from uncontrolled glaucoma using a specially designed contact applicator containing the OCT fiber, a focussing fiber optic and the fiber of the diode laser.
  
  
  RESULTS
  When the contact system was used, two layers could be differentiated: a superficial thick hyperreflective complex representing conjunctiva, Tenon's capsule, episclera and sclera, and a thinner hyporeflective layer representing the ciliary body. During cyclophotocoagulation, real-time OCT showed a clear and sudden thickening of the ciliary body in the treated area.
  
  
  CONCLUSIONS
  This new OCT device represents a first step towards visual, real-time imaging of cyclophotocoagulation. After further adaptation of the delivery system, further trials are needed to correlate OCT findings with aqueous production and intraocular pressure.
authors.affiliation: Department of Ophthalmology, Medical University Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany. hanshoerauf@yahoo.com
authors.forename: H
authors.initials: H
authors.lastname: Hoerauf
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: G
authors.initials: G
authors.lastname: Hüttmann
authors.forename: C
authors.initials: C
authors.lastname: Winter
authors.forename: T
authors.initials: T
authors.lastname: Schlote
mesh_terms: D002924:Ciliary Body / Q000473:pathology* / Q000601:surgery*; D003199:Computer Systems; D003941:Diagnostic Techniques, Ophthalmological; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D017075:Laser Coagulation / Q000379:methods*; D010865:Pilot Projects; D041623:Tomography, Optical Coherence