title: [Cellulite--the greatest skin problem in healthy people? An approach].
abstract: Cellulite or so called orange peel skin affects 80-90 % of all females. It is not considered as a pathological condition but as aesthetically disturbing dimpling of the skin seen most commonly on the thighs and buttocks. Despite its high prevalence, there have been only a few scientific investigations into the pathophysiology of cellulite reflected in the medical literature. A lack of knowledge regarding specific aetiopathogenetic factors and pathogenesis at large currently limits treatment options. The preferred hypotheses about the origin of cellulite include: gender specific dimorphic skin architecture, altered connective tissue septae, vascular changes and inflammatory processes. The most widely discussed management options include: attenuation of aggravating factors, physical procedures including laser therapy and application of topical incorporating actives. The latter approach has been evidence-based with respect to caffeine liposomal cream and retinol cream.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, Germany. Tatjana.Pavicic@med.uni-muenchen.de
authors.forename: Tatjana
authors.initials: T
authors.lastname: Pavicic
authors.forename: Claudia
authors.initials: C
authors.lastname: Borelli
authors.forename: Hans Christian
authors.initials: HC
authors.lastname: Korting
mesh_terms: D000273:Adipose Tissue / Q000166:cytology* / Q000187:drug effects* / Q000601:surgery; D003357:Cosmetic Techniques; D003879:Dermatologic Agents / Q000008:administration & dosage*; D062109:Dermatologic Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012016:Reference Values; D012867:Skin / Q000166:cytology* / Q000187:drug effects*; D013518:Surgery, Plastic / Q000379:methods*
chemical_list: D003879:Dermatologic Agents