Rubeosis and anterior segment ischemia associated with systemic cryoglobulinemia.
OBJECTIVE
To report two cases of iris neovascularization associated with systemic cryoglobulinemia.


METHODS
Retrospective case report.


METHODS
Patient chart review and review of literature.


RESULTS
Two patients with iris neovascularization in the absence of retinal ischemia were subsequently found to have systemic cryoglobulinemia. Successful treatment of one patient's underlying lymphoma led to stabilization and resolution of neovascularization.


CONCLUSIONS
Systemic cryoglobulinemia may be associated with anterior segment ischemia and neovascularization, and should be considered in the differential diagnosis of iris neovascularization in the absence of apparent retinal ischemia.
Telander
David G
DG
Ocular Inflammatory Disease Center, Jules Stein Eye Institute, and the Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Holland
Gary N
GN
Wax
Martin B
MB
Van Gelder
Russell N
RN
D000328:Adult; D000869:Anterior Eye Segment / Q000098:blood supply*; D001284:Atrophy; D003449:Cryoglobulinemia / Q000150:complications*; D015355:Glaucoma, Neovascular / Q000209:etiology; D006801:Humans; D007498:Iris / Q000098:blood supply* / Q000473:pathology; D007511:Ischemia / Q000209:etiology*; D009389:Neovascularization, Pathologic / Q000209:etiology*; D012189:Retrospective Studies