Acanthosis nigricans following single lung transplantation: a case report.
Acanthosis nigricans was observed 3 months after single lung transplantation in a 51-year-old African American woman with idiopathic pulmonary fibrosis. The patient had no endocrinological abnormalities and was not taking any medications known to cause acanthosis nigricans; extensive investigation did not reveal an underlying malignant process. Because acanthosis nigricans may occur as a paraneoplastic phenomenon, it is important to rule out an underlying malignancy. This is especially important in solid-organ transplant recipients receiving chronic immunosuppressive therapy.
Pandya
Chirag
C
Huron Hospital/Cleveland Clinic Health System, Cleveland, Ohio, USA.
Blazey
Holli
H
Budev
Marie M
MM
Mehta
Atul C
AC
Minai
Omar A
OA
D000052:Acanthosis Nigricans / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D001741:Black or African American / Q000706:statistics & numerical data; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016040:Lung Transplantation / Q000009:adverse effects* / Q000276:immunology; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology; D011658:Pulmonary Fibrosis / Q000601:surgery; D012307:Risk Factors
D007166:Immunosuppressive Agents