title: Endogenous Candida endophthalmitis.
abstract: Intraocular Candida infections, although uncommon, represent an important clinical problem owing to the potential for visual loss, which can be bilateral. Candida chorioretinitis and endophthalmitis are complications of systemic candidiasis with extension of the fungal pathogens to the uvea and retina. Early diagnosis and prompt management significantly affect the visual prognosis for these patients. This review evaluates the current literature on Candida endophthalmitis and includes discussion on presentation, diagnosis and management strategies. New systemic and intravitreal antifungal agents are also reviewed in the context of the management of intraocular fungal infection.
authors.affiliation: Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, City Road, London EC1V 2PD, UK. ahmedsallam11@yahoo.com
authors.forename: Ahmed
authors.initials: A
authors.lastname: Sallam
authors.forename: William
authors.initials: W
authors.lastname: Lynn
authors.forename: Peter
authors.initials: P
authors.lastname: McCluskey
authors.forename: Sue
authors.initials: S
authors.lastname: Lightman
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy; D009877:Endophthalmitis / Q000175:diagnosis* / Q000188:drug therapy; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans
chemical_list: D000935:Antifungal Agents