title: Giant angioleiomyoma in extremity: report of two cases.
abstract: Angioleiomyomas are smooth muscle tumors that occur most often in the extremities and are usually less than 2 cm in diameter. We present 2 case reports of giant angioleiomyoma. Case 1 was a 51-year-old woman with a 5-year history of a slowly growing mass 12x10 cm in diameter in the right posterior thigh. The tumor was larger than any previously reported. Case 2 was a 72-year-old man with an 8-year history of a slowly growing mass 6x6 cm in diameter in the left palm. The tumor was unique in that it grew to a giant size in the hand of the elderly patient. Magnetic resonance imaging of both cases confirmed the tumors' presence in the subcutis. T1-weighted images showed homogenous signal isointense to muscle. On T2-weighted images, areas of hyperintensity and hypointensity intermingled. Three-dimensional gadolinium-enhanced magnetic resonance angiography showed rapid initial enhancement followed by a gradual increase in enhancement, suggesting that the tumors were rich in vessels. Microscopic examination revealed numerous vascular channels embedded within a huge smooth muscle component.
authors.affiliation: Department of Radiology, Kurume University School of Medicine, Japan. sn4735@med.kurume-u.ac.jp
authors.forename: Shuji
authors.initials: S
authors.lastname: Nagata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nishimura
authors.forename: Masafumi
authors.initials: M
authors.lastname: Uchida
authors.forename: Naofumi
authors.initials: N
authors.lastname: Hayabuchi
authors.forename: Michihisa
authors.initials: M
authors.lastname: Zenmyou
authors.forename: Suguru
authors.initials: S
authors.lastname: Fukahori
mesh_terms: D000368:Aged; D018229:Angiomyoma / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006225:Hand / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013848:Thigh / Q000473:pathology*
chemical_list: D003287:Contrast Media