title: Principles of antimicrobial therapy.
abstract: The most compelling reason for practicing judicious antimicrobial use is to facilitate therapeutic success. The definition of therapeutic success has changed in recent years, however; not only does success include eradication of infection, but it must now include avoidance of resistance. If the goal of antimicrobial therapy is to achieve sufficient concentrations at the site of infection such that the infecting organism is killed, therapy should be successful.
authors.affiliation: Department of Anatomy, Physiology, and Pharmacology, 109 Greene Hall, College of Veterinary Medicine, Auburn University, AL 36849, USA. boothdm@auburn.edu
authors.forename: Dawn Merton
authors.initials: DM
authors.lastname: Boothe
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D024881:Drug Resistance, Bacterial; D008826:Microbial Sensitivity Tests / Q000662:veterinary*; D010818:Practice Patterns, Physicians'; D019155:Veterinary Drugs / Q000008:administration & dosage / Q000627:therapeutic use; D014730:Veterinary Medicine
chemical_list: D000900:Anti-Bacterial Agents; D019155:Veterinary Drugs