title: Organocatalytic enantioselective conjugate additions to enones.
abstract: Conjugate addition reactions of a wide range of nucleophilic enol species with enones, catalyzed by a cinchona alkaloid derived thiourea organocatalyst, have been developed with attending good yields and high enantioselectivities under a mild reaction condition. The general method provides an efficient approach to the preparation of versatile building blocks possessing various functional groups.
authors.affiliation: Department of Chemistry, University of New Mexico, Albuquerque, NM 87131-0001, USA.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Liansuo
authors.initials: L
authors.lastname: Zu
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
authors.forename: Hexin
authors.initials: H
authors.lastname: Xie
authors.forename: Wenhu
authors.initials: W
authors.lastname: Duan
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D004952:Esters; D007659:Ketones; D009570:Nitriles