title: [Pancreatic transplant].
abstract: Diabetes mellitus is a health concern of the first order, given the high level of associated morbidity and mortality. The objective, in order to slow down the advance of its complications before they become irreversible, is based on correct metabolic control. The high rate of morbidity associated with the surgery of the vascularized pancreas transplant and the high index of rejection have for three decades formed an obstacle to this being considered a valid alternative in the treatment of these patients. Nowadays the pancreas transplant has come to occupy a key position, thanks to the new regimes of immunosuppression and to the perfection of surgical techniques. In this article we review the evolution of the pancreas transplant from its beginnings to its present state.
authors.affiliation: Departamento de Cirugía General, Clínica Universitaria de Navarra, 31008, Pamplona, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Montiel
authors.forename: F
authors.initials: F
authors.lastname: Pardo
authors.forename: F
authors.initials: F
authors.lastname: Rotellar
authors.forename: V
authors.initials: V
authors.lastname: Valentí
authors.forename: C
authors.initials: C
authors.lastname: Pastor
authors.forename: J
authors.initials: J
authors.lastname: Alvarez Cienfuegos
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D003929:Diabetic Neuropathies / Q000517:prevention & control; D003930:Diabetic Retinopathy / Q000517:prevention & control; D004739:England; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006084:Graft Rejection; D006085:Graft Survival; D049673:History, 20th Century; D006801:Humans; D016381:Islets of Langerhans Transplantation / Q000379:methods; D016030:Kidney Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects / Q000266:history / Q000379:methods / Q000401:mortality; D018579:Patient Selection; D011183:Postoperative Complications; D011446:Prospective Studies; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D013548:Sweden; D013997:Time Factors; D014019:Tissue Donors; D014481:United States