Principles of antimicrobial therapy.
The most compelling reason for practicing judicious antimicrobial use is to facilitate therapeutic success. The definition of therapeutic success has changed in recent years, however; not only does success include eradication of infection, but it must now include avoidance of resistance. If the goal of antimicrobial therapy is to achieve sufficient concentrations at the site of infection such that the infecting organism is killed, therapy should be successful.
Boothe
Dawn Merton
DM
Department of Anatomy, Physiology, and Pharmacology, 109 Greene Hall, College of Veterinary Medicine, Auburn University, AL 36849, USA. boothdm@auburn.edu
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D024881:Drug Resistance, Bacterial; D008826:Microbial Sensitivity Tests / Q000662:veterinary*; D010818:Practice Patterns, Physicians'; D019155:Veterinary Drugs / Q000008:administration & dosage / Q000627:therapeutic use; D014730:Veterinary Medicine
D000900:Anti-Bacterial Agents; D019155:Veterinary Drugs