title: Internal jugular vein thrombosis associated with acute mastoiditis in a pediatric age.
abstract: OBJECTIVE
  To discuss the clinical aspects and management of internal jugular vein thrombosis associated with acute otitis media.
  
  
  METHODS
  Case reports and review of the literature.
  
  
  METHODS
  University hospital, tertiary referral center.
  
  
  METHODS
  The authors describe two cases of internal jugular vein thrombosis, without sigmoid sinus thrombosis, secondary to acute otomastoiditis.
  
  
  METHODS
  Jugular vein thrombosis was diagnosed in both cases by observation of filling defects of the involved jugular bulb on contrast-enhanced computed tomography and confirmed by conventional magnetic resonance and magnetic resonance venography.
  
  
  RESULTS
  Both patients recovered after recanalization of the vessel concomitant to anticoagulation and antibiotic treatment associated with a simple mastoidectomy.
  
  
  CONCLUSIONS
  Internal jugular vein thrombosis may be a complication of acute otitis media, without involvement of the sigmoid sinus and with a starting point in the jugular bulb. Anticoagulation associated with antibiotic therapy can be considered a safe and effective treatment. Surgery should only be performed to eliminate the source of infection from the middle ear and mastoid.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Brescia, Italy. redaelli@med.unibs.it
authors.forename: Luca Oscar
authors.initials: LO
authors.lastname: Redaelli de Zinis
authors.forename: Roberto
authors.initials: R
authors.lastname: Gasparotti
authors.forename: Chiara
authors.initials: C
authors.lastname: Campovecchi
authors.forename: Giacomo
authors.initials: G
authors.lastname: Annibale
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Barezzani
mesh_terms: D000208:Acute Disease; D000658:Amoxicillin / Q000627:therapeutic use; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007601:Jugular Veins / Q000473:pathology*; D008297:Male; D008417:Mastoiditis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010033:Otitis Media / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010690:Phlebography; D013407:Sulbactam / Q000627:therapeutic use; D013927:Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; C035444:sultamicillin; D000667:Ampicillin; D000658:Amoxicillin; D013407:Sulbactam