Antibody nanoarrays with a pitch of approximately 20 nanometers.
We have developed a strategy for preparing antibody nanoarrays by DNA templating. In the resulting tetragonal antibody arrays, each spot is a similarly orientated, individual antibody molecule (IgG). The separation between two adjacent IgG molecules is only approximately 20 nm.
He
Yu
Y
Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA.
Tian
Ye
Y
Ribbe
Alexander E
AE
Mao
Chengde
C
D000906:Antibodies / Q000032:analysis / Q000737:chemistry* / Q000276:immunology; D000937:Antigen-Antibody Reactions; D000941:Antigens / Q000737:chemistry* / Q000276:immunology; D004247:DNA / Q000737:chemistry* / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes; D007074:Immunoglobulin G / Q000737:chemistry / Q000276:immunology; D018625:Microscopy, Atomic Force; D049329:Nanostructures / Q000737:chemistry*
D000906:Antibodies; D000941:Antigens; D000939:Epitopes; D007074:Immunoglobulin G; D004247:DNA