Are placebo-controlled trials ethical in areas where current guidelines recommend therapy? Yes.
Cohen
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AT
Vascular Medicine Group, Vascular Department, King's College Hospital, London, UK. alexander.cohen@kcl.ac.uk
Maillardet
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LM
D000925:Anticoagulants / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D032984:Ethics, Research; D000077425:Fondaparinux; D017408:Guidelines as Topic; D006801:Humans; D010919:Placebos; D011134:Polysaccharides / Q000627:therapeutic use*; D012107:Research Design; D013923:Thromboembolism / Q000188:drug therapy*; D020246:Venous Thrombosis / Q000188:drug therapy*
D000925:Anticoagulants; D010919:Placebos; D011134:Polysaccharides; D000077425:Fondaparinux