Regulation of the NMDA receptor: implications for neuropsychological development.
Recent work has shown that zinc is involved in the developmental regulation of neurotrophins and N-methyl-D-aspartate (NMDA) receptors, controlling use of glutamate as a neurotransmitter in the central nervous system (CNS). This is particularly important in the hippocampus, a region of the brain involved in learning and memory, and is an intriguing link to the role of zinc in neuropsychological development.
Levenson
Cathy W
CW
Program in Neuroscience and Department of Nutrition, Food and Exercise Sciences, 237 Biomedical Research Facility, Florida State University, Tallahassee, FL 32306-4340, USA. levenson@neuro.fsu.edu
D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000378:metabolism; D002490:Central Nervous System / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D018698:Glutamic Acid / Q000378:metabolism; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008959:Models, Neurological; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism*; D015032:Zinc / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid; D015032:Zinc