title: Highly diastereoselective preparation of anti-1,2-diols by catalytic addition of alkynylsilanes to alpha-silyloxyaldehydes.
abstract: The catalytic, diastereoselective coupling of alpha-silyloxy aldehydes and alkynylsilanes catalyzed by a nickel(0) N-heterocyclic carbene complex provides an effective entry to anti-1,2-diols. The scope of couplings and extent of diastereoselection are excellent across a range of substrates.
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors.forename: Kanicha
authors.initials: K
authors.lastname: Sa-ei
authors.forename: John
authors.initials: J
authors.lastname: Montgomery
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D012821:Silanes