The first high-resolution DNA "methylome".
Cytosine methylation plays a crucial role in the regulation of gene expression and the control of genome stability in higher eukaryotes. Despite its importance for normal development, the degree and genome-wide distribution of DNA methylation has remained largely unknown. In this issue of Cell, fill this gap by presenting a high-resolution map of DNA methylation in the genome of the flowering plant Arabidopsis.
Schöb
Hanspeter
H
Institute of Plant Biology and Zürich-Basel Plant Science Center, University of Zürich, Zollikerstrasse 107, CH-8008 Zürich, Switzerland. hampe@botinst.unizh.ch <hampe@botinst.unizh.ch>
Grossniklaus
Ueli
U
D000818:Animals; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D043171:Chromosomal Instability / Q000235:genetics; D002874:Chromosome Mapping / Q000379:methods; D019175:DNA Methylation; D018744:DNA, Plant / Q000235:genetics*; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D018745:Genome, Plant / Q000235:genetics*; D006801:Humans; D009154:Mutation / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis
D018744:DNA, Plant