A severe case of neonatal toxic shock syndrome-like exanthematous disease with superantigen-induced high T cell response.
Most newborn patients with a neonatal type of toxic shock syndrome (TSS), called neonatal TSS-like exanthematous disease (NTED), exhibit mild clinical symptoms. We present the case of a patient with NTED who exhibited exceptionally severe clinical symptoms and an adult-type T cell response to the causative toxin TSS toxin-1.
Miki
Mizuka
M
Department of Pediatrics, Matsue Red Cross Hospital, Tokyo Women's Medical University, Tokyo, Japan.
Uchiyama
Takehiko
T
Kato
Hidehito
H
Nishida
Hiroshi
H
Takahashi
Naoto
N
D001427:Bacterial Toxins / Q000276:immunology*; D004768:Enterotoxins / Q000276:immunology*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007231:Infant, Newborn; D012772:Shock, Septic / Q000276:immunology* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000276:immunology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D018089:Superantigens / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal