title: Very late thrombosis of a drug-eluting stent deployed during primary angioplasty for ST-elevation myocardial infarction.
abstract: Drug-eluting stents, despite being very effective in reducing restenosis after percutaneous coronary interventions, are associated with a low but definite risk of late thrombotic occlusion with adverse clinical events. To date, the incidence and overall risk of late thrombosis of drug-eluting stents after primary percutaneous coronary interventions for ST-elevation myocardial infarction are not well defined because of the relative paucity of evidence-based data. We report the case of an angiographically confirmed paclitaxel-eluting stent thrombosis, occurring 20 months after successful primary percutaneous coronary intervention in a 41-year-old woman. To the best of our knowledge, this is the most delayed case of paclitaxel-eluting stent thrombosis described so far.
authors.affiliation: Cardiology Department, Sandro Pertini Hospital, ASL Roma B, Rome, Italy. stefanorigattieri@yahoo.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Rigattieri
authors.forename: Roberto
authors.initials: R
authors.lastname: Patrizi
authors.forename: Pasquale
authors.initials: P
authors.lastname: Silvestri
authors.forename: Cristian
authors.initials: C
authors.lastname: Di Russo
authors.forename: Carmine
authors.initials: C
authors.lastname: Musto
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ferraiuolo
authors.forename: Antonio
authors.initials: A
authors.lastname: Palamara
authors.forename: Paolo
authors.initials: P
authors.lastname: Loschiavo
mesh_terms: D000328:Adult; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects* / Q000379:methods; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D017239:Paclitaxel / Q000008:administration & dosage; D019233:Retreatment; D018570:Risk Assessment; D017131:Thrombectomy / Q000379:methods; D013997:Time Factors
chemical_list: D017239:Paclitaxel