title: The dose-area product, a new parameter for the dosimetry of narrow photon beams.
abstract: In the dosimetry of narrow photon fields with side lengths of the order of 1 cm, the traditional parametrisation via the absolute dose on the beam axis and the relative lateral dose distribution has to deal with the difficulty to find sufficiently small detectors and to adjust them accurately on the narrow-beam axis. This can be avoided by reconsidering the parametrisation, using as normalization factor the surface integral of the dose in the plane perpendicular to the beam axis, abbreviated as the "dose-area product" (DAP). We investigated and confirmed the ability of a large-area parallel-plate ionisation chamber, with a sensitive volume shaped as a flat cylinder of 81.6 mm diameter and 2 mm thickness, to perform the integration over the full lateral dose profile of narrow photon beams with side lengths up to 5 cm. The lateral adjustment of this large-area detector relative to a narrow photon beam is not critical. The large-area ionisation chamber was calibrated in terms of the DAP by reference to a 0.3 cm3 ionisation chamber. A field-size dependent "modified output factor" was defined as the ratio of the DAP measured at 5 cm phantom depth for 100 cm SSD, and the monitor reading. A prominent phenomenon of narrow photon fields is the field-size and source-distance independence of the relative axial profile of the DAP as function of the thickness of a pre-absorber or of the depth in a phantom. For narrow-beam treatment planning in IMRT, the DAP is combined with the energy- and field size-dependent relative lateral dose distribution which is represented, for example, by a Gaussian convolution kernel. Another useful feature of the DAP is the possibility of its direct control during patient irradiation by means of an on-line monitor with spatial resolution, arranged in the accessory holder.
authors.affiliation: Pius-Hospital, Clinic of Radiotherapy and Oncology, Oldenburg. armand.f.djouguela.ouentcheu@mail.uni-oldenburg.de
authors.forename: Armand
authors.initials: A
authors.lastname: Djouguela
authors.forename: Dietrich
authors.initials: D
authors.lastname: Harder
authors.forename: Ralf
authors.initials: R
authors.lastname: Kollhoff
authors.forename: Antje
authors.initials: A
authors.lastname: Rühmann
authors.forename: Kay C
authors.initials: KC
authors.lastname: Willborn
authors.forename: Björn
authors.initials: B
authors.lastname: Poppe
mesh_terms: D002138:Calibration; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D017785:Photons; D011881:Radiotherapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods*