title: The investigation and management of chronic neutropenia in children.
abstract: Unravelling the cause of a neutropenia poses a complex diagnostic challenge. The differential diagnosis ranges from life threatening disease to transient benign causes of little clinical significance. This review offers a practical guide to investigating the neutropenic child, and highlights features that merit specialist referral. Therapeutic options, the role of long term follow up, and the complications of severe chronic neutropenia are considered.
authors.affiliation: Epidemiology and Genetics Unit, Department of Health Sciences, University of York, UK.
authors.forename: R M
authors.initials: RM
authors.lastname: James
authors.forename: S E
authors.initials: SE
authors.lastname: Kinsey
mesh_terms: D002648:Child; D002908:Chronic Disease; D003937:Diagnosis, Differential; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D008134:Long-Term Care / Q000379:methods; D009503:Neutropenia / Q000209:etiology* / Q000628:therapy; D012017:Referral and Consultation
chemical_list: D016179:Granulocyte Colony-Stimulating Factor