title: [Pharmacological correction of energy metabolism disturbance in the inflammatory-dystrophic process in the periodontium].
abstract: The influence of lipoic acid on the energy homeostasis in rats with chronic generalized parodontitis has been investigated. Lipoic acid possesses the energy-saving activity, which is related to an increase in oxidative phosphorylation efficiency.
authors.forename: V D
authors.initials: VD
authors.lastname: Luk''ianchuk
authors.forename: O A
authors.initials: OA
authors.lastname: Shpulina
mesh_terms: D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000581:Amidohydrolases / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D004789:Enzyme Activation; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005260:Female; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D010085:Oxidative Phosphorylation; D010510:Periodontal Diseases / Q000188:drug therapy* / Q000378:metabolism; D051381:Rats; D008063:Thioctic Acid / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D008063:Thioctic Acid; D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase; D000581:Amidohydrolases; C019946:creatininase