title: Incisional hernia after liver transplantation.
abstract: BACKGROUND
  Incisional hernia is a potential complication of orthotopic liver transplantation (OLT), with various options for repair.
  
  
  METHODS
  We conducted a retrospective review of a series of adult patients with incisional hernias after OLT to identify risk factors and to compare methods of repair.
  
  
  RESULTS
  Incisional hernia repair was performed in 44 of 959 patients (4.6%) who underwent OLT from 1999 to 2005. Mean age at time of OLT was 53 years, and 73% were men. One or more complications of OLT occurred in 33 patients (75%) and included reoperation for bile leak or hemoperitoneum (34%), pulmonary problems (27%), early acute rejection (7%), and severe ascites and retransplantation (5% each). Incisional hernia was diagnosed at 419 days (range 62 to 1,524 days) and repaired at 471 days (range 109 to 1,581 days) after OLT. Presentation included pain or discomfort (78%) and incarceration or strangulation (5%); 17% were asymptomatic. Herniorrhaphy techniques included fascial repair with onlay polypropylene mesh reinforcement (n=25, 57%); fascial repair only (n=15, 34%); or inlay mesh sewn to fascial edges (n=4, 9%). Complications of repair included recurrence in seven patients (16%) and wound infection and seroma in one patient each. Recurrence occurred in five patients with primary repair and two with mesh techniques (33% versus 6%, p=0.04).
  
  
  CONCLUSIONS
  Incisional hernia is a late complication of OLT for which male gender and early post-OLT complications are risk factors. Repair is safe when undertaken after acute problems have resolved and is best accomplished using mesh reinforcement of autologous tissue.
authors.affiliation: Division of Liver and Pancreas Transplantation, Department of Surgery, Dumont-UCLA Transplant Center, David Geffen School of Medicine at UCLA, 650 C.E. Young Drive South, Los Angeles, CA 90095, USA.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Vardanian
authors.forename: Douglas G
authors.initials: DG
authors.lastname: Farmer
authors.forename: Rafik M
authors.initials: RM
authors.lastname: Ghobrial
authors.forename: Ronald W
authors.initials: RW
authors.lastname: Busuttil
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Hiatt
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D046449:Hernia, Abdominal / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013396:Suction; D013524:Surgical Flaps; D013536:Suture Techniques; D013537:Sutures; D016896:Treatment Outcome