title: The effect of high temperature intraoperative molding on bioabsorbable PLLA-PGA craniofacial fixation.
abstract: Bioabsorbable internal fixation has become an established part of the surgeons' armamentarium. There are several unique aspects of bioabsorbable polymers that can enhance their versatility. One of these is the application of heat to adapt the implant. Hot-tip cautery has been used for years to cut and otherwise customize bioabsorbable implants intraoperatively. As the tips of these devices can reach temperatures of over 1,000 degrees C, there is the potential that such practice can modify the degradation properties of these polymers. This study was performed to better understand the extent to which this potential exists. Screw heads of an 82:18 poly-L-lactic acid and poly-glycolic acid copolymer were modified by repeated passage of a hot-tip cautery wire, deforming the hex geometry to that of a ball. There was no significant difference between the glass transition temperature (approximately 59 degrees C) and inherent viscosity (approximately 1.45 dL/g) of treated and untreated screw heads, indicating no overall change in these properties throughout the mass of the screw head. Additionally, these properties were measured and comparisons made between the treated screw heads and untreated plates made of the same polymer during 28-day exposure to an in vitro bath (pH 7.4, 37 degrees C). The glass transition temperature and inherent viscosity exhibited declines during this period, with no significant differences between the two groups. Collectively, these results suggest that hot-tip cautery results in no substantial changes in the degradation characteristics of this polymer.
authors.affiliation: Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA. billsp@uic.edu
authors.forename: William S
authors.initials: WS
authors.lastname: Pietrzak
authors.forename: Barry L
authors.initials: BL
authors.lastname: Eppley
mesh_terms: D020341:Absorbable Implants; D001863:Bone Screws; D002425:Cautery / Q000009:adverse effects*; D006358:Hot Temperature / Q000009:adverse effects*; D019344:Lactic Acid / Q000737:chemistry*; D011091:Polyesters; D011100:Polyglycolic Acid / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D011091:Polyesters; D011108:Polymers; D011100:Polyglycolic Acid; D019344:Lactic Acid; C033616:poly(lactide)