Asymmetric aza-Diels-Alder reaction of Danishefsky's diene with imines in a chiral reaction medium.
The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky's diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid catalyst or organic solvent. Chiral ionic liquids are recycled while their efficiency is preserved.
Pégot
Bruce
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Laboratoire de Chimie des Procédés et Substances Naturelles, ICMMO, CNRS UMR 8182, Université Paris-Sud, 91405 Orsay Cedex, France. brucepeg@hotmail.com
Nguyen
Van Buu Olivier
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Gori
Didier
D
Vo-Thanh
Giang
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