Raltitrexed and pemetrexed studies in mesothelioma have not shown improved quality of life nor prolonged survival compared with effective pleurodesis with thoracoscopic talc poudrage.
Aelony
Yossef
Y
D002945:Cisplatin / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005971:Glutamates / Q000627:therapeutic use*; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008654:Mesothelioma / Q000150:complications* / Q000188:drug therapy*; D000068437:Pemetrexed; D010997:Pleural Neoplasms / Q000150:complications* / Q000188:drug therapy*; D018700:Pleurodesis / Q000379:methods*; D011788:Quality of Life; D011799:Quinazolines / Q000627:therapeutic use*; D013627:Talc; D013876:Thiophenes / Q000627:therapeutic use*; D016896:Treatment Outcome
D005971:Glutamates; D011799:Quinazolines; D013876:Thiophenes; D000068437:Pemetrexed; D013627:Talc; D006147:Guanine; C068874:raltitrexed; D002945:Cisplatin