title: Fluorescence quenching immunoassay performed in an ionic liquid.
abstract: We describe the first example of immunoanalysis performed within an ionic liquid with minimal deleterious effect; our results bode well for the development of second-generation biosensors, particularly in applications involving poorly water soluble analytes including pesticides, phospholipids, and illicit drugs.
authors.affiliation: Chemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. bakerga1@ornl.gov
authors.forename: Sheila N
authors.initials: SN
authors.lastname: Baker
authors.forename: Eric B
authors.initials: EB
authors.lastname: Brauns
authors.forename: T Mark
authors.initials: TM
authors.lastname: McCleskey
authors.forename: Anthony K
authors.initials: AK
authors.lastname: Burrell
authors.forename: Gary A
authors.initials: GA
authors.lastname: Baker
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D001896:Boron Compounds; D005453:Fluorescence; D007118:Immunoassay / Q000379:methods*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds