title: [Thrombocytopenia and other extrahepatic manifeststions of hepatitis C virus infection--case report].
abstract: Authors present a case of forty seven years old woman with thrombocytopenia in the course of hepatitis C virus infection. Thrombocytopenia might be related to immunological mechanisms or be an effect of hypersplenism. Moreover mixed cryoglobulinemia, lymphocytic autoimmune thyroiditis with hypothyroidism and other laboratory abnormalities (impaired rate of lymphocytes CD4 to CD8, increase of B cells and natural killer cells, hypocomplementemia, hypergammaglobulinemia, increase of immune complexes concentration) were revealed. Above-mentioned abnormalities might be an effect of hepatitis C virus infection.
authors.affiliation: Akademia Medyczna w Gdańsku, Klinika Chorób Wewnetrznych, Endokrynologii i Zaburzeń Hemostazy, Instytut Chorób Wewnetrznych. monika-berendt@wp.pl
authors.forename: Monika
authors.initials: M
authors.lastname: Berendt-Obołończyk
authors.forename: Ewa
authors.initials: E
authors.lastname: Kazimierska
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Sworczak
mesh_terms: D001327:Autoimmune Diseases / Q000276:immunology / Q000821:virology; D003449:Cryoglobulinemia / Q000276:immunology / Q000821:virology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D013921:Thrombocytopenia / Q000276:immunology / Q000821:virology*; D013967:Thyroiditis, Autoimmune / Q000276:immunology / Q000821:virology*