title: Characterization of severe small airway disease in a puppy using computed tomography.
abstract: A young Golden Retriever dog developed severe respiratory distress following an initial clinical diagnosis of infectious tracheobronchitis. Severe expiratory flow limitation, associated with exertional respiratory distress and hypoxemia was present. Thoracic images obtained with conventional radiography were characterized by hyperinflation and abnormal bronchial and alveolar patterns. Computed tomography was performed and in conjunction with pulmonary functional changes was diagnostic of small airway disease. The dog was treated with a variety of antibiotics, anti-inflammatory agents, and antitussives, but the clinical signs worsened and the puppy was euthanized. Pathologic examination confirmed severe small airway disease, with emphysema and bronchiolitis.
authors.affiliation: Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA 01536, USA.
authors.forename: Kimberly B
authors.initials: KB
authors.lastname: Winters
authors.forename: Amy S
authors.initials: AS
authors.lastname: Tidwell
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Rozanski
authors.forename: Richard
authors.initials: R
authors.lastname: Jakowski
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Hoffman
mesh_terms: D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000151:congenital / Q000000981:diagnostic imaging*; D004285:Dogs; D008297:Male; D010375:Pedigree; D014057:Tomography, X-Ray Computed / Q000662:veterinary