Endemic mycoses: blastomycosis, histoplasmosis, and sporotrichosis.
The endemic mycoses are diverse group of fungi that share several characteristics. They are able to cause disease in healthy hosts, they each occupy a specific ecologic niche in the environment, and they exhibit temperature dimorphism, existing as molds in the environment at temperature of 25 degrees C to 30 degrees C, and as yeasts, or spherules in the case of coccidioidomycosis, at body temperatures. This article discusses histoplasmosis and blastomycosis. Sporotrichosis, which differs in that it is usually a localized lymphocutaneous infection, is included because it shares the characteristics of endemic mycoses.
Kauffman
Carol A
CA
University of Michigan Medical School, Ann Arbor, MI 48109, USA. ckauff@umich.edu
D000935:Antifungal Agents / Q000627:therapeutic use; D001759:Blastomycosis / Q000175:diagnosis* / Q000188:drug therapy; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D013174:Sporotrichosis / Q000175:diagnosis* / Q000188:drug therapy
D000935:Antifungal Agents