Transitional cell carcinoma of the endometrium: a case report and review of the literature.
We report a case of primary transitional cell carcinoma of the endometrium and review the literature which reveals only 12 cases described to date. The patient presented with postmenopausal bleeding, and there were no distinctive clinical features. An endometrial sample taken at hysteroscopy was reported as a poorly differentiated, papillary, nonserous carcinoma with probable squamous metaplasia. The tumor removed at hysterectomy and bilateral salpingo-oophorectomy was almost all transitional cell with small areas of endometrioid, glandular differentiation. Immunohistochemistry demonstrated a similar immunoprofile to endometrioid carcinoma of the endometrium and different from reported cases of transitional cell carcinoma of the ovary and of the urinary tract.
Ahluwalia
Monica
M
Department of Cellular Pathology, Good Hope Hospital, Sutton Coldfield, West Midlands, B75 7RR, UK.
Light
Anton Michael
AM
Surampudi
K
K
Finn
Catherine B
CB
D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D016130:Immunophenotyping; D010052:Ovariectomy; D017698:Postmenopause; D011960:Receptors, Estrogen / Q000032:analysis; D014592:Uterine Hemorrhage; D014746:Vimentin / Q000032:analysis
D002272:Carcinoembryonic Antigen; D011960:Receptors, Estrogen; D014746:Vimentin