Organization in the descending tracts of the dorsolateral funiculus in the cat.
Organization of the fibers in the descending tracts of the dorsolateral funiculus of the cervical spinal cord was investigated in cats. The spinal cord was penetrated with microelectrodes at 400 mum intervals in the medio-lateral direction at the c5/c6 and c6/c7 segmental borders. Silicon substrate microelectrodes with a linear arrangement of activated iridium contacts were used. The stimulus consisted of a 20 ms train of charge balanced biphasic current pulses at 330 Hz. The evoked activities from selected forelimb muscles were acquired into computer. Only the data points with an activation threshold of less than 35 muA were considered in the analysis. Muscle contractions were mostly in the form of short twitches. In both spinal segments, an area of high threshold was found in the middle of the dorsolateral funiculus. Majority of the muscles studied had a dorsal or ventral concentration of activation points. The distal muscles were mostly activated in the ventro-lateral aspect of the funiculus, while the elbow muscle maps spread to both dorsal and ventral sides. These results show a functional organization in both cervical segments studied, with overlapping regions between the areas dedicated for each forelimb muscle.
Tie
Yanmei
Y
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Sahin
Mesut
M
Sundararajan
Nappinnai
N
D000818:Animals; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D001931:Brain Mapping; D002415:Cats; D004558:Electric Stimulation; D004576:Electromyography; D005121:Extremities / Q000294:innervation / Q000502:physiology; D008297:Male; D008839:Microelectrodes; D009044:Motor Cortex / Q000033:anatomy & histology / Q000502:physiology; D009068:Movement / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation* / Q000502:physiology; D011712:Pyramidal Tracts / Q000033:anatomy & histology* / Q000502:physiology*; D012012:Red Nucleus / Q000033:anatomy & histology / Q000502:physiology; D013045:Species Specificity; D013116:Spinal Cord / Q000033:anatomy & histology* / Q000502:physiology*