Found in translation: A new player in EMT.
Epithelial mesenchymal transition (EMT) is a complex process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. Screening for genes mediating EMT and cancer metastasis, Waerner, Alacakaptan, and colleagues identified ILEI, a cytokine-like protein that plays an essential role in EMT, tumor growth, and late steps of metastasis.
Mackenzie
Natalia C
NC
Germ Cell Development, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen 37070, Germany.
Raz
Erez
E
D000818:Animals; D002461:Cell Line, Transformed; D002471:Cell Transformation, Neoplastic; D004847:Epithelial Cells / Q000166:cytology*; D006801:Humans; D007378:Interleukins / Q000096:biosynthesis* / Q000378:metabolism; D008648:Mesoderm / Q000166:cytology*; D051379:Mice; D008819:Mice, Nude; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000209:etiology / Q000503:physiopathology
D007378:Interleukins