[Rheumatoid arthritis and cardiovascular complications].
Rheumatoid arthritis is associated with increased morbidity and mortality due to cardiovascular events. Elevated concentrations of acute-phase proteins and cytokines and endothelial dysfunction, demonstrated also by lack of traditional risk factors, play an important role in these complications. Antirheumatic drug treatment can modify the frequency and severity of cardiovascular events.
Seidel
W
W
Abteilung Rheumatologie, Medizinische Klinik IV, Universität Leipzig, Liebigstrasse 22, 04103 Leipzig, Deutschland. wolfram.seidel@medizin.uni-leipzig.de
Hecker
M
M
Wagner
U
U
Häntzschel
H
H
D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality; D002423:Cause of Death; D015897:Comorbidity; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011379:Prognosis; D012307:Risk Factors
D018501:Antirheumatic Agents; D005938:Glucocorticoids