title: Ataxia-telangiectasia complicated by craniopharyngioma--a new observation.
abstract: Ataxia-telangiectasia is a rare autosomal recessive neurodegenerative disorder with high incidence of malignancy including leukemias, lymphomas, and solid tumors. Central nervous system tumors in ataxia telangiectasia include medulloblastomas and gliomas. We describe a 13-year-old girl with ataxia telangiectasia who developed craniopharyngioma and non-Hodgkin's lymphoma. To our knowledge, this is the first case of ataxia telangiectasia complicated by craniopharyngioma in the English literature.
authors.affiliation: Department of Pediatrics, Division of Child Neurology, Jordan University Hospital, Amman, Jordan. amasri@ju.edu.jo
authors.forename: Amira T
authors.initials: AT
authors.lastname: Masri
authors.forename: Faris G
authors.initials: FG
authors.lastname: Bakri
authors.forename: Azmy M
authors.initials: AM
authors.lastname: Al-Hadidy
authors.forename: Awni F
authors.initials: AF
authors.lastname: Musharbash
authors.forename: Maisa
authors.initials: M
authors.lastname: Al-Hussaini
mesh_terms: D000293:Adolescent; D001260:Ataxia Telangiectasia / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D001921:Brain / Q000473:pathology; D003241:Consanguinity; D003397:Craniopharyngioma / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis / Q000235:genetics; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000175:diagnosis / Q000235:genetics; D009460:Neurologic Examination; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000601:surgery