An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones.
An efficient one-pot, three-component method for the preparation of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and various multi-substituted quinoline-3-carbonitrile derivatives has been developed through the Michael addition to enaminones, which was achieved by both microwave irradiation and conventional heating.
Tu
Shu-Jiang
SJ
Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant Xuzhou, Jiangsu, 211116, PR China. laotu@xznu.edu.cn
Jiang
Bo
B
Jia
Run-Hong
RH
Zhang
Jun-Yong
JY
Zhang
Yan
Y
Yao
Chang-Sheng
CS
Shi
Feng
F
D000166:Acridines / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
D000166:Acridines; D006576:Heterocyclic Compounds, 4 or More Rings; D009570:Nitriles; D011804:Quinolines; C037219:quinoline