title: Biological tooth replacement.
abstract: Teeth develop from a series of reciprocal interactions that take place between epithelium and mesenchyme during development of the mouth that begin early in mammalian embryogenesis. The molecular control of key processes in tooth development such as initiation, morphogenesis and cytodifferentiation are being increasingly better understood, to the point where this information can be used as the basis for approaches to produce biological replacement teeth (BioTeeth). This review outlines the current approaches, ideas and progress towards the production of BioTeeth that could form an alternative method for replacing lost or damaged teeth.
authors.affiliation: Department of Craniofacial Development, Dental Institute, Kings College London, Floor 28 Guy's Hospital, London SE1 9RT, UK.
authors.forename: Rachel
authors.initials: R
authors.lastname: Sartaj
authors.forename: Paul
authors.initials: P
authors.lastname: Sharpe
mesh_terms: D001672:Biocompatible Materials; D006801:Humans; D008648:Mesoderm / Q000502:physiology; D009805:Odontogenesis / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*; D014070:Tooth; D014182:Transplantation, Autologous
chemical_list: D001672:Biocompatible Materials