[Effect of combination of Chinese and Western medicines on sinus rhythm maintenance in patients with auricular fibrillation after conversion].
OBJECTIVE
To investigate the curative effects of irbesartan, amiodarone and Wenxin Granule (WG), applied alone or in combination, on sinus rhythm maintenance in patients with auricular fibrillation (AF) after conversion.


METHODS
Forty-one patients of persistent AF, after their fibrillation being converted, were divided into three groups randomly, and treated with amiodarone (group A, n=14), irbesartan and amiodarone (group B, n=15), and WG plus irbesartan and amiodarone (group C, n=12) respectively for 6 months.


RESULTS
Compared with that before treatment, the inner diameter of atria sinistrum reduced in group B and C, and the reduction in the latter was superior to that in the former (P < 0.05); the diameter of left ventricle also reduced in group C (P < 0.05); and the maintenance rate of sinus rhythm was higher in group C than that in group A (P < 0.05).


CONCLUSIONS
Combined therapy of Chinese and Western medicines shows synergistic effect of anti-arrhythmia.
Xie
Pei-yi
PY
Department of Cardiology, Tongde Hospital, Hangzhou. xiepiyi@163.com
Shen
Sheng-hui
SH
D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D001713:Biphenyl Compounds / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D000077405:Irbesartan; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D013777:Tetrazoles / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D013777:Tetrazoles; D000077405:Irbesartan; D000638:Amiodarone