Granulatoside A, a starfish steroid glycoside, enhances PC12 cell neuritogenesis induced by nerve growth factor through an activation of MAP kinase.
Qi
Jianhua
J
Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan.
Han
Chunguang
C
Sasayama
Yumi
Y
Nakahara
Hiroko
H
Shibata
Takahiro
T
Uchida
Koji
K
Ojika
Makoto
M
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology*; D020928:Mitogen-Activated Protein Kinases / Q000187:drug effects* / Q000378:metabolism*; D008968:Molecular Conformation; D009414:Nerve Growth Factors / Q000494:pharmacology*; D016501:Neurites / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D016716:PC12 Cells; D051381:Rats; D013215:Starfish / Q000737:chemistry*; D013237:Stereoisomerism; D013256:Steroids / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013997:Time Factors
D006027:Glycosides; D009414:Nerve Growth Factors; D013256:Steroids; C517959:granulatoside A; D020928:Mitogen-Activated Protein Kinases