A novel skin cream containing a mixture of human growth factors and cytokines for the treatment of adverse events associated with photodynamic therapy.
OBJECTIVE
Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) is becoming a more popular dermatologic procedure. Newer protocols have virtually eliminated any associated untoward effects. Phototoxicity, although rare, can still occur and requires aggressive post-therapy care. Recently, a new biorestorative skin care cream, containing human growth factors and cytokines, was used to treat 2 severe cases of PDT-associated phototoxicity.


METHODS
This paper describes 2 case reports of severe phototoxicity following ALA-PDT treatments. The novel skin care cream was utilized in both cases phototoxicity.


RESULTS
Complete resolution of the phototoxic reaction was seen, leaving both patients with normal skin texture and tone.


CONCLUSIONS
This novel skin care cream may prove useful in wound healing following treatment with lasers and light sources or dermatologic surgery.
Gold
Michael H
MH
Gold Skin Care Center, Nashville, TN 37215, USA. goldskin@goldskincare.com
Biron
Julie
J
D000287:Administration, Topical; D000328:Adult; D000622:Aminolevulinic Acid / Q000009:adverse effects*; D016207:Cytokines / Q000008:administration & dosage*; D005260:Female; D006133:Growth Substances / Q000008:administration & dosage*; D006801:Humans; D009824:Ointments; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects*; D012871:Skin Diseases / Q000139:chemically induced / Q000188:drug therapy*
D016207:Cytokines; D006133:Growth Substances; D009824:Ointments; D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid