Gelastic seizures involving the right parietal lobe.
Gelastic seizures have been described in various epilepsies arising from the temporal or frontal lobes, although the most commonly encountered form is related to the presence of an hypothalamic hamartoma. We report a patient with gelastic seizures involving the right parietal lobe. Our patient, a 32-year-old man, underwent video-EEG monitoring, interictal and ictal brain SPECTs during gelastic seizures. Subtraction ictal SPECT co-registered to MRI (SISCOM), was performed to localize any ictal hyperperfusion during these gelastic seizures. The seizures consisted of brief staring followed by smiling and laughing. Electroencephalography during the gelastic seizures showed rhythmic sharp waves in the right parietal lobe. SISCOM showed ictal hyperperfusion in the right parietal lobe and medial portions of right cerebellum. Our findings suggest that the right parietal lobe may actively participate in the particular epileptogenic network generating gelastic seizures.
Shin
Hee-Young
HY
Department of Neurology, Samsung Medical center, Sungkyunkwan University School of Medicine, Korea.
Hong
Seung Bong
SB
Joo
Eun Yeon
EY
Tae
Woo Suk
WS
Han
Sun Jung
SJ
Cho
Jae Wook
JW
Seo
Dae Won
DW
Kim
Sun Hyung
SH
Lee
Jong-Min
JM
Kim
Sun I
SI
D000328:Adult; D000927:Anticonvulsants; D002529:Cerebellar Nuclei / Q000000981:diagnostic imaging / Q000473:pathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010296:Parietal Lobe / Q000000981:diagnostic imaging / Q000473:pathology*; D015899:Tomography, Emission-Computed, Single-Photon
D000927:Anticonvulsants