Modulating the rate of a native ligation coupling between tripyrrole derivatives by using specific dsDNA sequences.
The intrinsic recognition code associated with dsDNA allows either accelerating or retarding of a native chemical ligation reaction between tripyrrole ligands. The rate changes most probably stem from the sequence-dependent characteristics of the dsDNA-ligand complexes.
Dodero
Verónica I
VI
Departamento de Química Organica, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Mosquera
Manuel
M
Blanco
Juan B
JB
Castedo
Luis
L
Mascareñas
José L
JL
D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000737:chemistry*; D008024:Ligands; D011758:Pyrroles / Q000737:chemistry*
D008024:Ligands; D011758:Pyrroles; D004247:DNA