Single maxillary central incisor, holoprosencephaly, and holoprosencephaly-like phenotype.
Three patients--one with alobar holoprosencephaly and two with a holoprosencephaly-like phenotype--are reported with no identifiable mutations. In each case, one parent had a single maxillary central incisor (SMCI). We briefly review the holoprosencephaly-like phenotype and present a table of 25 conditions with SMCI.
Richieri-Costa
A
A
Serviço de Genética Clínica, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, São Paulo, Brazil. richieri@usp.br
Ribeiro
Lucilene Arilho
LA
D000328:Adult; D002648:Child; D002971:Cleft Lip / Q000473:pathology; D005260:Female; D016142:Holoprosencephaly / Q000235:genetics / Q000473:pathology*; D006801:Humans; D007180:Incisor / Q000002:abnormalities*; D007223:Infant; D008297:Male; D008437:Maxilla / Q000002:abnormalities; D010641:Phenotype; D014071:Tooth Abnormalities / Q000235:genetics / Q000473:pathology