title: High-resolution CT of the chest in children and young adults who were born prematurely: findings in a population-based study.
abstract: OBJECTIVE
  The purpose of this study was to use a scoring system for high-resolution CT in the evaluation of radiologic findings in young people born extremely preterm and to examine the reproducibility of this scoring system.
  
  
  METHODS
  High-resolution CT of the lungs was assessed in 72 children born at a gestational age of < or = 28 weeks or with a birth weight of < or = 1,000 g within a defined region in western Norway in 1982-1985 (n = 40) or in 1991-1992 (n = 32). All images were analyzed by two pediatric radiologists using a scoring system in which a total of 14 features were assessed.
  
  
  RESULTS
  Sixty-three (88%) of the subjects had abnormal findings, the most common being linear opacities (n = 52), triangular opacities (n = 42), air trapping (n = 19), and mosaic perfusion (n = 10). Right and left lungs were equally affected. There were fewer abnormalities in the younger age group (born in 1991-1992). Intraobserver agreement and interobserver agreement were moderate (weighted kappa = 0.54 and kappa = 0.52, respectively). Fifty-six of the 72 children had a clinical diagnosis of bronchopulmonary dysplasia, and the median total score and the median scores of the four most common findings were higher in the bronchopulmonary dysplasia group; however, the differences were not statistically significant.
  
  
  CONCLUSIONS
  High-resolution CT in young people of preterm birth revealed abnormal radiologic findings in 81.3% of the patients at age 10 years and 92.5% at age 18 years. Linear, triangular, and subpleural opacities were the most common. The reproducibility of the applied scoring system was acceptable.
authors.affiliation: Department of Radiology, Section of Paediatrics, Haukeland University Hospital, 5021 Bergen, Norway. stein.magnus.aukland@helse-bergen.no
authors.forename: Stein Magnus
authors.initials: SM
authors.lastname: Aukland
authors.forename: Thomas
authors.initials: T
authors.lastname: Halvorsen
authors.forename: Kari Røine
authors.initials: KR
authors.lastname: Fosse
authors.forename: Anne Kjersti
authors.initials: AK
authors.lastname: Daltveit
authors.forename: Karen
authors.initials: K
authors.lastname: Rosendahl
mesh_terms: D000293:Adolescent; D001997:Bronchopulmonary Dysplasia / Q000150:complications / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D015588:Observer Variation; D011247:Pregnancy; D047928:Premature Birth; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed