title: The experimental induction of hypophosphataemia in goats using anion exchange columns.
abstract: 1. Inorganic phosphate was selectively removed from the circulating blood of five anaesthetized goats by means of columns of anion-exchange resin. Concentrations of other ions were unaffected by the column.2. Rates of inorganic phosphate extraction in excess of 5 m-moles/hr caused a fall in plasma inorganic phosphate of up to 50% in 30 min.3. In four of the goats the calculated inorganic phosphate mobilization rate rose sharply to a maximum between 5.8 and 12.7 m-moles/hr and then fell progressively as more phosphate was removed.4. During the course of the experiments a fall in blood pressure occurred, accompanied by a rise in blood glucose. The reasons for this are discussed.
authors.forename: H W
authors.initials: HW
authors.lastname: Symonds
authors.forename: R J
authors.initials: RJ
authors.lastname: Treacher