title: [Multifunctional sphingolipid, sphingosine (long-chain base) 1-phosphate: physiological role, metabolism, and intracellular dynamics].
authors.affiliation: Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Kihara
mesh_terms: D000818:Animals; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D015195:Drug Design; D000068876:Fingolimod Hydrochloride; D006801:Humans; D007107:Immune System; D007166:Immunosuppressive Agents; D008246:Lysophospholipids / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology; D018919:Neovascularization, Physiologic; D010744:Phosphoric Monoester Hydrolases / Q000502:physiology; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000502:physiology; D011409:Propylene Glycols; D049349:Receptors, Lysosphingolipid / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000502:physiology; D015398:Signal Transduction; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D000099157:Sphingosine Kinase
chemical_list: D000068876:Fingolimod Hydrochloride; D007166:Immunosuppressive Agents; D008246:Lysophospholipids; D008565:Membrane Proteins; D010744:Phosphoric Monoester Hydrolases; D017853:Phosphotransferases (Alcohol Group Acceptor); D011409:Propylene Glycols; D049349:Receptors, Lysosphingolipid; D029701:Saccharomyces cerevisiae Proteins; D013110:Sphingosine; D000099157:Sphingosine Kinase; C060506:sphingosine 1-phosphate; C113962:LCB4 protein, S cerevisiae; C401298:sphingosine-1-phosphate phosphatase