Dual diagnosis of pemphigus vulgaris and connective tissue disease.
This is a retrospective analysis of patients with pemphigus vulgaris and connective tissue disease (CTD) present as systemic lupus erythematosus, mixed CTD, or both. Pemphigus vulgaris was severe, difficult to treat, but eventually responded to therapy, resulting in a remission. In 6 patients, the CTD was stable and controlled with symptomatic therapy, and in 7 patients required systemic therapy. Life-threatening systemic involvement in systemic lupus erythematosus or mixed CTD-such as renal, cardiac, and neurologic-were absent in these patients on 8 years (range 3-18 years) of follow-up. There are two limitations to this study. First, it is a retrospective study. Second, no other disease control groups were used for comparison purposes.
Malik
Mohsin
M
Department of Medicine, New England Baptist Hospital, Boston, MA 02120, USA.
Ahmed
A Razzaque
AR
D000368:Aged; D003240:Connective Tissue Diseases / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000150:complications / Q000175:diagnosis*; D012189:Retrospective Studies