title: Age does not affect airway pH and ammonia as determined by exhaled breath measurements.
abstract: Measurement of airway pH has been used as a diagnostic and monitoring tool in a variety of pulmonary diseases in adults. These diseases occur across a wide age range. Few investigations have addressed the effects of aging on airway pH and ammonia. The aim of this study was to determine whether exhaled breath condensate (EBC) measurements of pH and ammonia differ in older and younger populations of normal subjects. Twenty-three normal younger individuals (median age-24 years) and 25 normal older participants (median age-72 years) were investigated by measuring EBC for pH and ammonia using recommended methodologies. EBC ammonia and pH values were not significantly different between younger and older individuals. Thus, we conclude that EBC ammonia and pH do not appear to be affected by age.
authors.affiliation: Department of Environmental and Occupational Health, College of Public Health, 13201 Bruce B. Downs Blvd., MDC 56, Tampa, FL 33612, USA. sbrooks@hsc.ust.edu
authors.forename: Stuart M
authors.initials: SM
authors.lastname: Brooks
authors.forename: Robert R
authors.initials: RR
authors.lastname: Haight
authors.forename: Robert L
authors.initials: RL
authors.lastname: Gordon
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000641:Ammonia / Q000032:analysis*; D001944:Breath Tests; D045853:Exhalation; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D012137:Respiratory System / Q000378:metabolism*
chemical_list: D000641:Ammonia