HIV and skin cancer.
AIDS produces profound alterations in normal immunity. Impaired cellular immunity permits new tumor formation as evidenced by the solid-organ transplant literature. The weakened cellular immune system of HIV-infected patients resembles in some ways the iatrogenic immunosuppression in solid-organ transplant recipients. This article summarizes what is known about skin cancer in the solid-organ transplant population and compares the immunodysregulation of HIV infection with the iatrogenic immunosuppression following solid-organ transplantation.
Honda
Kord S
KS
Division of Dermatology, Box 356524, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA. kordhnda@u.washington.edu
D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance; D012878:Skin Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy