Current noise in transport of hydrophobic ions through lipid bilayer membranes including diffusion polarization in the aqueous phase.
An exact treatment of the current noise spectrum produced by transport of hydrophobic ions through membranes is presented, including the coupling of the diffusion processes through both the aqueous phase and the membrane. Both the equilibrium and the steady state noise spectra are computed. The theory contains previous results as limiting cases. The structure of the spectra is discussed with emphasis upon how noise measurements can be used to estimate kinetic parameters, especially the rate of desorption from the membrane. For this restricted model there is no low frequency divergence in the non-equilibrium current noise, i.e., for the model treated there is no 1/f noise.
Jordan
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PC
Fakultät für Biologie, Universität Konstanz, D-7750 Konstanz, G.F.R.