title: Transient global left ventricular dysfunction in a localized myocardial infarction related to occlusion of the distal left anterior descending artery.
abstract: In some patients with acute myocardial infarction (MI), wall motion in the noninfarcted area declines globally despite localized myocardial damage. In most, an infarct-related lesion is the proximal part of the left anterior descending artery (LAD). Previous studies have reported that hypokinesis of remote myocardium may be related to multivessel disease, impaired coronary flow, or coronary flow reserve in nonculprit arteries. This report describes the case of a 53-year-old man who presented with severe global left ventricular (LV) dysfunction after an acute MI associated with distal LAD occlusion. Follow-up echocardiographic examination revealed nearly normalized LV function 5 days after the episode. We discuss a plausible mechanism of dysfunction of noninfarcted myocardium.
authors.affiliation: Cardiology Division, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
authors.forename: Seong Bo
authors.initials: SB
authors.lastname: Yoon
authors.forename: Sang Hak
authors.initials: SH
authors.lastname: Lee
authors.forename: Seonghoon
authors.initials: S
authors.lastname: Choi
authors.forename: Jae-Hun
authors.initials: JH
authors.lastname: Jung
authors.forename: Namho
authors.initials: N
authors.lastname: Lee
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001783:Blood Flow Velocity; D017023:Coronary Angiography; D003326:Coronary Circulation; D023921:Coronary Stenosis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D004452:Echocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy