High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.
An automatic data-collection system has been implemented and installed on seven insertion-device beamlines and a bending-magnet beamline at the ESRF (European Synchrotron Radiation Facility) as part of the SPINE (Structural Proteomics In Europe) development of an automated structure-determination pipeline. The system allows remote interaction with beamline-control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.
Beteva
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ESRF, 6 Rue Jules Horowitz, Grenoble, France.
Cipriani
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Cusack
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Delageniere
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Gabadinho
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Gordon
E J
EJ
Guijarro
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Hall
D R
DR
Larsen
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S
Launer
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L
Lavault
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CB
Leonard
G A
GA
Mairs
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McCarthy
A
A
McCarthy
J
J
Meyer
J
J
Mitchell
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E
Monaco
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Nurizzo
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Pernot
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P
Pieritz
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Ravelli
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RG
Rey
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Shepard
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W
Spruce
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D
Stuart
D I
DI
Svensson
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Theveneau
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Thibault
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Turkenburg
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Walsh
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McSweeney
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SM
D003625:Data Collection / Q000379:methods; D005796:Genes / Q000235:genetics*; D019451:Information Management; D015394:Molecular Structure; D011786:Quality Control; D012984:Software; D017356:Synchrotrons / Q000706:statistics & numerical data*