Phenolic glycosides with antioxidant activity from the stem bark of Populus davidiana.
Phytochemical study on the EtOAc-soluble fraction of the stem bark of Populus davidiana resulted in the isolation of 10 phenolic glycosides (1-10), which were identified on the basis of physicochemical and spectroscopic analyses. Among these, three new compounds, populosides A-C (1-3), were determined to be 2-coumaroylmethyl-4-hydroxyphenyl-beta-D-glucopyranoside, 2-coumaroylmethylphenyl-beta-D-glucopyranoside, and 2-feruoylmethylphenyl-beta-D-glucopyranoside, respectively. Compounds 1-10 were tested for their radical scavenging activity against an azo radical, ABTS*+. Of these, populosides A-C (1-3), populoside (4), grandidentatin (8), salireposide (9), and coumaroyl-beta-D-glucoside (10) exhibited antioxidant activity in this assay.
Zhang
Xinfeng
X
College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea, College of Pharmacy, Catholic University of Daegu, Gyeongbuk 712-702, Korea.
Thuong
Phuong Thien
PT
Min
Byung-Sun
BS
Ngoc
Tran Minh
TM
Hung
Tran Manh
TM
Lee
Ik Soo
IS
Na
MinKyun
M
Seong
Yeon-Hee
YH
Song
Kyung-Sik
KS
Bae
KiHwan
K
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005959:Glucosidases / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D007723:Korea; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D032107:Populus / Q000737:chemistry*; D027861:Prunus / Q000201:enzymology
D000975:Antioxidants; D006027:Glycosides; D010636:Phenols; D005959:Glucosidases