title: [Side effects of specific immunotherapy in patients with hymenoptera venom allergy].
abstract: The aim of this study was to estimate safety of specific immunotherapy to insects' venom. The frequency of side effects was compared in two groups of patients: subjects with hypersensitivity to insects' venom only and patients with allergy to other allergens. In the examined group of 32 patients with Hymenoptera venoms allergy skin prick tests with common aeroallergens were performed in 30 subjects. In 18 patients (60%) at least one test was positive. In 23 patients (71.9%) immunotherapy with Hymenoptera venom was connected with side effects observed just after administration of vaccine. They were mainly local reactions (itching, redness and oedema). In 6 patients late reactions were observed. No correlation has been found between frequency of side effects of immunotherapy and positive results of skin prick tests. However systemic reactions were revealed only in the group of patients with at least one positive result of skin prick tests.
authors.affiliation: Klinika Alergologii Akademii Medycznej w Gdańsku. kubaama@poczta.onet.pl
authors.forename: Jakub
authors.initials: J
authors.lastname: Lata
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Specjalski
authors.forename: Magdalena
authors.initials: M
authors.lastname: Kołaczkowska
authors.forename: Marta
authors.initials: M
authors.lastname: Chełmińska
authors.forename: Marek
authors.initials: M
authors.lastname: Niedoszytko
authors.forename: Ewa
authors.initials: E
authors.lastname: Jassem
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001180:Arthropod Venoms / Q000008:administration & dosage / Q000276:immunology / Q000506:poisoning*; D005260:Female; D006801:Humans; D006927:Hymenoptera; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D007167:Immunotherapy / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D007299:Insect Bites and Stings / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012882:Skin Tests / Q000379:methods
chemical_list: D001180:Arthropod Venoms