title: Cognitive and psychiatric predictors of medical treatment adherence among older adults in primary care clinics.
abstract: OBJECTIVE
  Medical treatment non-adherence among older adults is common and represents a significant public health care concern. Treatment non-adherence has been associated with a number of factors in older adults; however few studies have delineated the role of cognition and psychiatric status.
  
  
  METHODS
  Data were collected from 212 ethnically diverse older primary care patients as part of a larger study.
  
  
  METHODS
  Cognitive status was evaluated with the Mattis Dementia Rating scale (DRS). Psychiatric status was evaluated using the Geriatric Depression Scale (GDS) and the Beck Anxiety Inventory (BAI). Treatment adherence was assessed by the total number of missed healthcare appointments and by physician and patient ratings. Physician ratings of patients' understanding of medical instructions were also obtained.
  
  
  METHODS
  A series of multiple regression analyses were conducted to determine cognitive and psychiatric predictors for each measure of treatment adherence.
  
  
  RESULTS
  GDS and DRS memory scores were both independent predictors of the total number of missed medical appointments, F(7,55) = 2.34, p = 0.038. GDS score was also shown to be a significant predictor of physician ratings of patients' understanding of medical instructions, F(7,33) = 0.89, p = 0.031. Neither cognitive performance nor psychiatric status was associated with patient or physician ratings of treatment adherence.
  
  
  CONCLUSIONS
  Measures of cognitive functioning and depression severity were supported as predictors of objective measures of treatment adherence but they were not associated with physician or patient ratings of adherence. Patient depression may influence physician ratings of patients' comprehension of medical instructions.
authors.affiliation: Department of Psychiatry, University of California, San Francisco, CA 94143-0984, USA. scottm@lppi.ucsf.edu
authors.forename: R Scott
authors.initials: RS
authors.lastname: Mackin
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Areán
mesh_terms: D000368:Aged; D001071:Appointments and Schedules; D003072:Cognition Disorders / Q000523:psychology; D003866:Depressive Disorder / Q000523:psychology; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000523:psychology*; D008875:Middle Aged; D010349:Patient Compliance; D011320:Primary Health Care; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors