title: Effect of chitosan on the growth of human colonic bacteria.
abstract: Growth of 6 bacterial strains representing dominant members of the human colonic microflora was measured in the presence of 0.025, 0.05 and 0.5 % chitosan (from shrimp shells, with a 97 % final degree of deacetylation). The effect of chitosan was variable and dependent on bacterial species. The most susceptible to chitosan were bacteria belonging to genera Bacteroides and Clostridium (91-97% growth inhibition). On the other hand, Roseburia sp., Eubacterium sp. and Faecalibacterium sp. were more resistant (63-83 % inhibition of growth). Chitosan can thus be considered as one of the means for influencing the bacterial population in the human colon.
authors.affiliation: Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Prague, Czechia. simunek@iapg.cas.cz
authors.forename: J
authors.initials: J
authors.lastname: Simůnek
authors.forename: G
authors.initials: G
authors.lastname: Tishchenko
authors.forename: B
authors.initials: B
authors.lastname: Hodrová
authors.forename: H
authors.initials: H
authors.lastname: Bartonová
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification; D048271:Chitosan / Q000378:metabolism / Q000494:pharmacology*; D003106:Colon / Q000382:microbiology*; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D048271:Chitosan