Study of calix[4]resorcinarene-dopamine complexation in mixed phospholipid monolayers formed at the air-water interface.
We have studied the physical properties of monolayers formed by calix[4]resorcinarene and in mixtures with dipalmitoyl phosphatidylcholine (DPPC) in various molar ratios formed at the air-water interface and at presence of dopamine in water subphase by means of measurements of surface pressure and dipole potential. We showed that both calix[4]resorcinarene as well as its mixture with DPPC form stable monolayers at the water subphase. The presence of dopamine resulted in an increase of the mean molecular area and in a decrease of the compressibility modulus of the monolayers. For mixed monolayers at higher content of calix[4]resorcinarene (> 0.2 molar fraction) a deviation from ideal miscibility took place especially for monolayers in a solid state. This can be connected with formation of aggregates of calix[4] resorcinarene. Lowest miscibility and weakest interaction of dopamine with a monolayer was observed for calix[4]resorcinarene molar fraction of 0.33 in the monolayer.
Vitovic
P
P
Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Computer Sciences, Comenius University, 842 48 Bratislava, Slovakia.
Nikolelis
D P
DP
Hianik
T
T
D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry*; D000327:Adsorption; D000388:Air; D047250:Calixarenes / Q000737:chemistry*; D004298:Dopamine / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry; D013499:Surface Properties; D014867:Water / Q000737:chemistry*
D010636:Phenols; C121325:calix(4)arene; C466160:resorcinarene; D014867:Water; D047250:Calixarenes; D015060:1,2-Dipalmitoylphosphatidylcholine; D010649:Phenylalanine; D004298:Dopamine