Photoadaptation: a path toward rational phototherapy protocols.
Photoadaptation is defined as the diminished future response to equivalent doses of irradiation. It is most often estimated in vivo by looking at changes in the minimal erythema dose with subsequent doses of UV radiation. Although photoadaptation's mechanism of action is poorly understood, Palmer et al. help clarify the clinical significance of photoadaptation for the dosimetry of UV-based phototherapy.
Hamzavi
Iltefat
I
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan 48202, USA. iham2av1@hfhs.org
D000222:Adaptation, Physiological; D006801:Humans; D011565:Psoriasis / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012867:Skin / Q000187:drug effects*; D014467:Ultraviolet Therapy / Q000592:standards*