title: Effect of AC II, a herbal formulation on radiation-induced immunosuppression in mice.
abstract: A single dose of 6 Gy irradiation significantly reduced the total WBC count while in herbal formulation (AC II) treated groups it was found to be significantly increased. Similarly bone marrow cellularity and alpha-esterase positive cells, which were lowered by radiation, were partly restored in AC II treated groups. The data indicate that AC II can overcome the immunosuppression produced by irradiation.
authors.affiliation: Amala Ayurvedic Hospital, Amala Nagar, Thrissur, India.
authors.forename: Sheeja T
authors.initials: ST
authors.lastname: Tharakan
authors.forename: Girija
authors.initials: G
authors.lastname: Kuttan
authors.forename: Ramadasan
authors.initials: R
authors.lastname: Kuttan
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use*; D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000528:radiation effects; D001835:Body Weight / Q000187:drug effects / Q000528:radiation effects; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects; D004950:Esterases / Q000378:metabolism; D005720:Gamma Rays; D006462:Hemolytic Plaque Technique; D007108:Immune Tolerance / Q000187:drug effects / Q000528:radiation effects; D008515:Medicine, Ayurvedic; D051379:Mice; D008807:Mice, Inbred BALB C; D028321:Plant Preparations / Q000008:administration & dosage / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000276:immunology; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects
chemical_list: C514509:AC II herbal formulation; D000276:Adjuvants, Immunologic; D028321:Plant Preparations; D004950:Esterases