Tetrabenazine for hyperglycemic-induced hemichorea-hemiballismus.
We reported a 74-year-old woman with new-onset diabetes mellitus who presented with the sudden onset of mild left hemiparesis and marked left hemichorea-hemiballismus. Brain CT scan and MRI showed T1W, T2W, and DWI lesions in the right putamen and caudate, which have been previously reported in cases of hyperglycemic-induced hemichorea-hemiballismus (HIHH). The patient dramatically responded to tetrabenazine within a day. Subsequent dose reductions lead to a reemergence of symptoms. Tetrabenazine improves a variety of hyperkinetic movement disorders but, to our knowledge, its use has never been reported for HIHH.
Sitburana
Oraporn
O
Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USA.
Ondo
William G
WG
D000368:Aged; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use*; D002819:Chorea / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D020820:Dyskinesias / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D005260:Female; D007839:Functional Laterality / Q000187:drug effects; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D013747:Tetrabenazine / Q000627:therapeutic use*
D018726:Anti-Dyskinesia Agents; D013747:Tetrabenazine