Fluorescence quenching immunoassay performed in an ionic liquid.
We describe the first example of immunoanalysis performed within an ionic liquid with minimal deleterious effect; our results bode well for the development of second-generation biosensors, particularly in applications involving poorly water soluble analytes including pesticides, phospholipids, and illicit drugs.
Baker
Sheila N
SN
Chemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. bakerga1@ornl.gov
Brauns
Eric B
EB
McCleskey
T Mark
TM
Burrell
Anthony K
AK
Baker
Gary A
GA
D015374:Biosensing Techniques / Q000379:methods*; D001896:Boron Compounds; D005453:Fluorescence; D007118:Immunoassay / Q000379:methods*
C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds