[Sinus histiocytosis with massive lymphadenopathy].
OBJECTIVE
To explore the therapeutic strategy of sinus histiocytosis with massive lymphadenopathy (SHML).


METHODS
The six patients with SHML were treated with different therapeutic strategies.


RESULTS
Two of six patients were treated with radiation therapy and chemical therapy resulting in tumor lessened markedly. The tumor of other four cases disappeared after comprehensive treatment including operation, immunity and interferon therapy.


CONCLUSIONS
The comprehensive therapy, mainly including surgical treatment, is effective for SHML.
Li
Youzhong
Y
Department of Otorhinolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China. Liyouzhong196311@yahoo.com
Lu
Yongde
Y
Yang
Xinming
X
Zeng
Yici
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D007376:Interleukin-2 / Q000627:therapeutic use; D008206:Lymphatic Diseases / Q000150:complications / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D055815:Young Adult
D007376:Interleukin-2; D007372:Interferons