title: Parkinson's disease and genetics.
abstract: BACKGROUND
  Idiopathic Parkinson disease (IPD) is a condition of unknown cause. Several factors are believed to contribute to its onset, and many studies have been conducted in search of the possible etiology of Parkinson disease.
  
  
  RESULTS
  Genetic factors have become relevant when trying to explain the onset of Parkinson disease. The studies are divided into 2 categories: epidemiological and studies that analyze twins from families with members suffering from Parkinson disease, thus looking for the responsible genetic mutations. In this article we address this controversial topic, reviewing some of the most significant studies trying to provide evidence which relates genetics to Parkinson disease.
  
  
  CONCLUSIONS
  We present current epidemiological studies and the most important genetic factors related to Parkinson disease, including the latest information currently available on each issue.
authors.affiliation: Hospital de Clínicas José de San Martín, Huixquilucan, Estado de México, Mexico. jacobolester@hotmail.com
authors.forename: Jacobo
authors.initials: J
authors.lastname: Lester
authors.forename: Enrique
authors.initials: E
authors.lastname: Otero-Siliceo
mesh_terms: D006801:Humans; D040582:Inheritance Patterns / Q000235:genetics; D009154:Mutation / Q000235:genetics*; D010300:Parkinson Disease / Q000453:epidemiology* / Q000235:genetics*