[Unilateral swollen leg caused by a retroperitoneal ganglioneuroma].
METHODS
An 84-year-old man was admitted to our hospital because of a swollen left leg resembling deep venous thrombosis. Clinical conditions favoring thrombosis such as surgery, trauma, malignant tumor or immobilization were not evident. His medical and family history were non-contributory. He denied bowel or bladder dysfunction and did not complain of any back pain, discomfort or neurological symptoms. The enlargement of the leg was painless and unilateral. There were no deficits on physical examination. The neurological status of the patient was unremarkable.


METHODS
Ultrasonography was performed because deep vein thrombosis was suspected. Color-coded duplex revealed no thrombus in the veins of the left leg. Both femoral veins were compressible. The flow in the femoral vein was much less than in the other leg. Computed tomography demonstrated a solid lesion located in front of the spine displacing the inferior vena cava. CT-guided biopsy was performed. On histological examination it proved to be diagnostic of a ganglioneuroma.


METHODS
Initially low molecular weight heparin was administered. Surgical resection was recommended, but the patient opted not to undergo any further treatment at that time. Phenprocoumon was recommended to prevent deep vein thrombosis.


CONCLUSIONS
Ganglioneuroma is a rare, benign, well-differentiated, slow-growing tumor composed of sympathetic ganglion cells and mature stroma with a good prognosis. Its appearance in elderly persons is extremely rare and may imitate deep vein thrombosis caused by vessel compression. The appropriate treatment is surgical and complete excision is curative.
Brueck
M
M
Medizinische Klinik I, Klinikum Wetzlar. Martin.Brueck@hkw.med.uni-giessen.de
Bandorski
D
D
Rauber
K
K
Kramer
W
W
D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D004487:Edema / Q000000981:diagnostic imaging* / Q000209:etiology; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007866:Leg; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014463:Ultrasonography