Discovering innate immunity genes using differential display: a story of RNA helicases.
In this review we discuss the current literature for RNA helicases in response to RNA virus infection. We show the use of Differential Display Reverse Transcription PCR methodology (DD) to analyze virus-host interactions and we present current findings in dengue virus-induced gene expression of RNA helicases.
Ramirez-Ortiz
Zaida G
ZG
Center for Infectious Disease and Vaccine Research, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Warke
Rajas V
RV
Pacheco
Laura
L
Xhaja
Kris
K
Sarkar
Devanand
D
Fisher
Paul B
PB
Shaw
Sunil K
SK
Martin
Katherine J
KJ
Bosch
Irene
I
D002460:Cell Line; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases / Q000235:genetics / Q000378:metabolism*; D003715:Dengue / Q000276:immunology; D003716:Dengue Virus / Q000235:genetics / Q000276:immunology; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics* / Q000502:physiology; D000072640:Interferon-Induced Helicase, IFIH1; D007372:Interferons / Q000378:metabolism; D011971:Receptors, Immunologic
D011971:Receptors, Immunologic; D007372:Interferons; C452820:RIGI protein, human; C452815:IFIH1 protein, human; D000071457:DEAD Box Protein 58; D053487:DEAD-box RNA Helicases; D000072640:Interferon-Induced Helicase, IFIH1