title: Outcomes of antipsychotic drug use in community-dwelling elders with dementia.
abstract: This study used administrative data from a large health care insurer in the southeast United States to describe the utilization pattern and health care outcomes of antipsychotic drug use in community-dwelling elders with dementia. Claims data from 959 unique cases were analyzed to address research aims. Overall, 27% of the sample was dispensed antipsychotic drugs, with the most prevalent type being atypical antipsychotic drugs. Individuals on any type of antipsychotic drug experienced more delirium, depression, hip fracture, falls, and syncope than those not on these drugs, even after controlling for age, sex, comorbidity, and number of other drugs prescribed. Implications for practice are discussed.
authors.affiliation: School of Nursing, The Pennsylvania State University, 201 Health and Human Development Bldg., University Park, PA 16802, USA. amk20@psu.edu
authors.forename: Ann
authors.initials: A
authors.lastname: Kolanowski
authors.forename: Donna
authors.initials: D
authors.lastname: Fick
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Waller
authors.forename: Frank
authors.initials: F
authors.lastname: Ahern
mesh_terms: D000058:Accidental Falls / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D016009:Chi-Square Distribution; D003693:Delirium / Q000139:chemically induced; D003704:Dementia / Q000188:drug therapy*; D003863:Depression / Q000139:chemically induced; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D004363:Drug Utilization / Q000706:statistics & numerical data*; D005260:Female; D006302:Health Services Research; D006620:Hip Fractures / Q000139:chemically induced; D006801:Humans; D007344:Insurance Claim Reporting / Q000706:statistics & numerical data; D016015:Logistic Models; D008297:Male; D017063:Outcome Assessment, Health Care; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data; D011568:Psychiatric Nursing; D012111:Residence Characteristics; D012189:Retrospective Studies; D015144:Southeastern United States; D013575:Syncope / Q000139:chemically induced
chemical_list: D014150:Antipsychotic Agents