title: A knee-sparing distal femoral endoprosthesis using hydroxyapatite-coated extracortical plates. Preliminary results.
abstract: We used a knee-sparing distal femoral endoprosthesis in young patients with malignant bone tumours of the distal femur in whom it was possible to resect the tumour and to preserve the distal femoral condyles. The proximal shaft of the endoprosthesis had a coated hydroxyapatite collar, while the distal end had hydroxyapatite-coated extracortical plates to secure it to the small residual femoral condylar fragment. We reviewed the preliminary results of this endoprosthesis in eight patients with primary bone tumours of the distal femur. Their mean age at surgery was 17.years (14 to 21). The mean follow-up was 24 months (20 to 31). At final follow-up the mean flexion at the knee was 102 degrees (20 degrees to 120 degrees) and the mean Musculoskeletal Tumour Society score was 80% (57% to 96.7%). There was excellent osteointegration at the prosthesis-proximal bone interface with formation of new bone around the hydroxyapatite collar. The prosthesis allowed preservation of the knee and achieved a good functional result. Formation of new bone and remodelling at the interface make the implant more secure. Further follow-up is required to determine the long-term structural integrity of the prosthesis.
authors.affiliation: Department of Orthopaedic Oncology, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK. ajaygupta@hotmail.co.uk
authors.forename: A
authors.initials: A
authors.lastname: Gupta
authors.forename: R
authors.initials: R
authors.lastname: Pollock
authors.forename: S R
authors.initials: SR
authors.lastname: Cannon
authors.forename: T W R
authors.initials: TW
authors.lastname: Briggs
authors.forename: J
authors.initials: J
authors.lastname: Skinner
authors.forename: G
authors.initials: G
authors.lastname: Blunn
mesh_terms: D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials; D001860:Bone Plates; D017886:Durapatite; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery*; D005269:Femur / Q000601:surgery; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite