Assessment of ovarian reserve by using the follicle-stimulating hormone isoform distribution pattern to predict the outcome of in vitro fertilization.
Changes in FSH isoforms occur at temporally specific times during the menstrual cycle and reproductive lifespan. Changes in ratio in FSH isoforms may provide a sensitive test of ovarian reserve before IVF.
Letterie
Gerard S
GS
Northwest Center for Reproductive Sciences, Seattle, Washington 98119, USA.. ivfdoc@nwreprosci.com
Lee
James S
JS
Padmanabhan
Vasantha
V
D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000175:diagnosis / Q000628:therapy*; D017063:Outcome Assessment, Health Care / Q000379:methods; D010053:Ovary / Q000378:metabolism*; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D020033:Protein Isoforms / Q000097:blood; D014018:Tissue Distribution; D016896:Treatment Outcome
D015415:Biomarkers; D020033:Protein Isoforms; D005640:Follicle Stimulating Hormone