Comparing the regulatory behaviour of two cooperative, reversible enzyme mechanisms.
It is shown that both the reversible Hill equation and a generalised, reversible Monod-Wyman-Changeux equation can give analogous regulatory behaviour when embedded in a model metabolic pathway.
Olivier
B G
BG
Triple-J Group for Molecular Cell Physiology, Department of Biochemistry, University of Stellenbosch, Stellenbosch 7600, South Africa. bgoli@sun.ac.za
Rohwer
J M
JM
Snoep
J L
JL
Hofmeyr
J H S
JH
D002384:Catalysis; D003067:Coenzymes / Q000737:chemistry*; D003198:Computer Simulation; D004789:Enzyme Activation; D005246:Feedback; D008956:Models, Chemical; D008958:Models, Molecular; D009097:Multienzyme Complexes / Q000737:chemistry*; D013379:Substrate Specificity
D003067:Coenzymes; D009097:Multienzyme Complexes