Eccrine porocarcinoma and Bowen's disease arising in a seborrhoeic keratosis.
An association between seborrhoeic keratosis (SK) and malignant tumours is considered to be rare. We observed a case of eccrine porocarcinoma and Bowen's disease (BD) occurring synchronously, forming one lesion in a SK on the abdomen. It is controversial whether malignant neoplasms arising in SK occur only by chance or if pre-existing SK plays a role in pathogenesis. This case suggests an implication of pre-existing SK in the subsequent development of both BD and eccrine porocarcinoma.
Hoshina
D
D
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Akiyama
M
M
Hata
H
H
Aoyagi
S
S
Sato-Matsumura
K C
KC
Shimizu
H
H
D000369:Aged, 80 and over; D001706:Biopsy; D001913:Bowen's Disease / Q000473:pathology*; D002277:Carcinoma / Q000473:pathology*; D004439:Eccrine Glands; D005260:Female; D006801:Humans; D017492:Keratosis, Seborrheic / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*