title: Malvone A, a phytoalexin found in Malva sylvestris (family Malvaceae).
abstract: The isolation and structure of a phytoalexin, malvone A (2-methyl-3-methoxy-5,6-dihydroxy-1,4-naphthoquinone) is reported. Malvone A formation is induced in Malva sylvestris L. by the plant pathogen Verticillium dahliae. In a turbimetric assay for toxicity to V. dahliae, it had an ED50 value of 24 microg/ml. The structure of malvone A was determined by MS and NMR spectroscopy, and by X-ray crystallographic analysis. The X-ray analysis showed water molecules were located in channels that run along the a-axis.
authors.affiliation: A.S. Sadykov Institute of Bioorganic Chemistry, Academy of Science Uzbekistan, Tashkent, Uzbekistan.
authors.forename: Olga
authors.initials: O
authors.lastname: Veshkurova
authors.forename: Zamira
authors.initials: Z
authors.lastname: Golubenko
authors.forename: Egor
authors.initials: E
authors.lastname: Pshenichnov
authors.forename: Irina
authors.initials: I
authors.lastname: Arzanova
authors.forename: Vyacheslav
authors.initials: V
authors.lastname: Uzbekov
authors.forename: Elvira
authors.initials: E
authors.lastname: Sultanova
authors.forename: Shavkat
authors.initials: S
authors.lastname: Salikhov
authors.forename: Howard J
authors.initials: HJ
authors.lastname: Williams
authors.forename: Joseph H
authors.initials: JH
authors.lastname: Reibenspies
authors.forename: Lorraine S
authors.initials: LS
authors.lastname: Puckhaber
authors.forename: Robert D
authors.initials: RD
authors.lastname: Stipanovic
mesh_terms: D028501:Malva / Q000737:chemistry* / Q000145:classification / Q000382:microbiology; D015394:Molecular Structure; D009285:Naphthoquinones / Q000737:chemistry* / Q000302:isolation & purification*; D010935:Plant Diseases; D012717:Sesquiterpenes; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification*; D020172:Verticillium / Q000502:physiology; D000094162:Phytoalexins
chemical_list: D009285:Naphthoquinones; D012717:Sesquiterpenes; D013729:Terpenes; C516455:malvone A; D000094162:Phytoalexins