title: Bilateral renal metastases from osteosarcoma: A case report and review of the literature.
abstract: Improvements in multimodal therapy for osteosarcoma (OS) have increased event-free and overall survival. But have also led to a greater number of recurrences in uncommon sites. We report a young adult with OS who developed late bilateral renal relapse. Late recurrences to the kidneys have a more aggressive clinical behavior and poor prognosis documented by 15 cases of OS metastastic to the kidney in the literature. Two of those patients had a long survival after chemotherapy and surgery. This suggests that the disease can be controlled with early detection and treatment.
authors.affiliation: Department of Pediatric Oncology, Hospital do Câncer AC Camargo, São Paulo, Brazil. Isaka@terra.com.br
authors.forename: Luís Henrique Toshihiro
authors.initials: LH
authors.lastname: Sakamoto
authors.forename: Wellington
authors.initials: W
authors.lastname: Mendes
authors.forename: Marcela
authors.initials: M
authors.lastname: Pecora
authors.forename: Rodrigo Guimarães
authors.initials: RG
authors.lastname: Andrade
authors.forename: Maria Dirlei Ferreira
authors.initials: MD
authors.lastname: Begnani
authors.forename: Beatriz
authors.initials: B
authors.lastname: de Camargo
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary*; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D012516:Osteosarcoma / Q000556:secondary* / Q000628:therapy; D013977:Tibia / Q000473:pathology