Genotypic diversity and antibiotic susceptibility of Acinetobacter baumannii isolates in a Bulgarian hospital.
A set of 18 Acinetobacter baumannii isolates, collected prospectively in a Bulgarian hospital during episodes of increased A. baumannii occurrence during 2000-2002, was investigated for genotypic diversity and antibiotic susceptibility. Four genotypes were identified by amplified fragment length polymorphism genomic fingerprinting, one of which (type 1) accounted for 13 isolates, indicating that a specific strain was predominant. The single isolate allocated to type 2 was identified to European clone I. All isolates were resistant to multiple antibiotics, but most retained susceptibility to tobramycin and colistin, and all except one were susceptible to imipenem.
Dobrewski
R
R
Department of Clinical Microbiology, Military Medical Academy, Sophia, Bulgaria.
Savov
E
E
Bernards
A T
AT
van den Barselaar
M
M
Nordmann
P
P
van den Broek
P J
PJ
Dijkshoorn
L
L
D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002031:Bulgaria; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D014644:Genetic Variation; D006772:Hospitals, Military; D006801:Humans; D008826:Microbial Sensitivity Tests; D012150:Polymorphism, Restriction Fragment Length; D011446:Prospective Studies
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial