title: Thyroid eye disease presenting after cosmetic botulinum toxin injections.
abstract: A 53-year-old woman with left periorbital swelling 4 days after botulinum toxin injection in the lateral canthal area presented after noticing left eye prominence. Physical examination demonstrated proptosis and eyelid retraction. Computed tomography of the orbits confirmed extraocular muscle enlargement consistent with thyroid eye disease. In this case, the patient had development of proptosis after receiving botulinum toxin injections. Although the proptosis may represent progression of the patients' thyroid eye disease, it is worthwhile to consider incitation by botulinum toxin as a possible cause given its widespread use.
authors.affiliation: Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA. aharrison@umn.edu
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Harrison
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Erickson
mesh_terms: D018726:Anti-Dyskinesia Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000009:adverse effects*; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D049970:Graves Ophthalmopathy / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D007267:Injections; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins