Ultrastructural evaluation of explanted opacified Hydroview (H60M) intraocular lenses.
OBJECTIVE
To describe the ultrastructural appearance of explanted opacified Hydroview H60M intraocular lenses.


METHODS
14 explanted lenses were examined by scanning electron microscopy, and their appearance compared with a non-implanted H60M lens from the same time period. Wavelength-dispersive x ray spectroscopy (WDX) was performed on two opacified lenses.


RESULTS
Subsurface deposits were seen in all explanted opacified lenses. These deposits broke only onto the surface of more densely opacified lenses. WDX confirmed that the deposits contained both calcium and phosphorous, consistent with their being calcium apatite.


CONCLUSIONS
These findings challenge the widely accepted opinion that H60M intraocular lens opacification begins on the surface of the optic.
Knox Cartwright
Nathaniel E
NE
University of Bristol, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, UK.
Mayer
Eric J
EJ
McDonald
Brendan M
BM
Skinner
Andrew
A
Salter
Chris J
CJ
Tole
Derek M
DM
Sparrow
John M
JM
Dick
Andrew D
AD
Ferguson
David J P
DJ
D002118:Calcium / Q000032:analysis; D020878:Device Removal; D006801:Humans; D007910:Lenses, Intraocular; D008855:Microscopy, Electron, Scanning; D010758:Phosphorus / Q000032:analysis; D011475:Prosthesis Failure; D013499:Surface Properties
D010758:Phosphorus; D002118:Calcium