title: Phytochemical and antimicrobial study of an antidiabetic plant: Scoparia dulcis L.
abstract: The antimicrobial and antifungal effects of different concentrations of chloroform/methanol fractions of Scoparia dulcis were investigated. The isolated fractions were tested against different bacteria like Salmonella typhii, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Proteus vulgaris and fungal strains such as Alternaria macrospora, Candida albicans, Aspergillus niger, and Fusarium oxysporum. The isolated fractions exhibited significant antimicrobial and antifungal activity against all the tested organisms compared with respective reference drugs. The isolated fractions of S. dulcis showed properties like antimicrobial and antifungal activities that will enable researchers in turn to look for application-oriented principles.
authors.affiliation: Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar, India.
authors.forename: M
authors.initials: M
authors.lastname: Latha
authors.forename: K M
authors.initials: KM
authors.lastname: Ramkumar
authors.forename: L
authors.initials: L
authors.lastname: Pari
authors.forename: P N
authors.initials: PN
authors.lastname: Damodaran
authors.forename: V
authors.initials: V
authors.lastname: Rajeshkannan
authors.forename: T
authors.initials: T
authors.lastname: Suresh
mesh_terms: D000528:Alternaria / Q000187:drug effects; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005670:Fusarium / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry*; D011514:Proteus vulgaris / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012485:Salmonella typhi / Q000187:drug effects; D036721:Scoparia / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts