Comparative determination of xenobiotics adsorption.
Xenobiotic solutions of different concentrations were analyzed by TLC method before and after passing trough the column with adsorbent M and compared with adsorption on the active charcoal. The efficiency of adsorption on adsorbent M was higher, compared to active charcoal. The best adsorption, in the value 90 - 100%, have shown certain organochlorine and organophosphorus pesticides, that were dissolved in non-aqueous solvents. Efficiency of adsorbent M was also proven in vivo, when solutions of tested xenobiotics before adsorption have caused death of experimental animals, and after the adsorption on adsorbent M, all treated animals have survived and had just mild symptoms of poisoning.
Mijanović
Mirjana
M
Institute of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina.
Zaciragić
Asija
A
D000327:Adsorption; D000818:Animals; D002606:Charcoal; D002855:Chromatography, Thin Layer; D005260:Female; D008297:Male; D010575:Pesticides / Q000493:pharmacokinetics* / Q000633:toxicity; D015262:Xenobiotics / Q000493:pharmacokinetics* / Q000633:toxicity
D010575:Pesticides; D015262:Xenobiotics; D002606:Charcoal