title: Hypoglycaemia secondary to the secretion of pro-insulin like growth factor II by a metastatic neuroendocrine tumour with sarcomatous differentiation.
abstract: A patient presented with frequent episodes of spontaneous hypoglycaemia due to a disseminated neuroendocrine tumour with sarcomatous differentiation, secreting incompletely processed pro-insulin-like growth factor II (pro-IGF-II). Although the combination of GH and glucocorticoid therapy initially controlled the hypoglycaemia, there was a later escape necessitating frequent re-admissions to hospital. The patient deceased two weeks following her latest admission.
authors.affiliation: Department of Endocrinology, St Bartholomew's Hospital, London EC1A 7BE, UK.
authors.forename: Mia
authors.initials: M
authors.lastname: Morgan
authors.forename: Alexandra
authors.initials: A
authors.lastname: Nanzer
authors.forename: Cecilia
authors.initials: C
authors.lastname: Camacho-Hubner
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Kaltsas
authors.forename: John P
authors.initials: JP
authors.lastname: Monson