Relationship between spermatozoon movement velocity and expression of testicular isoform of angiotensin-converting enzyme on their surface.
The expression of testicular isoform of angiotensin-converting enzyme on the surface of human spermatozoa was evaluated by flow cytometry with monoclonal antibodies to epitopes of C-terminal domain of human angiotensin-converting enzyme and the mean path, mean curvilinear and straight-line velocities were determined by computer analysis of spermatozoon movement. A positive correlation between the expression of testicular isoform of angiotensin-converting enzyme on the cell surface and spermatozoon movement velocity was revealed.
Aleksinskaya
M A
MA
M V Lomonosov Moscow State University. almaran80@mail.ru
Nikolaeva
M A
MA
Danilov
S M
SM
Kuz'michyov
L N
LN
Levchuk
T N
TN
Yelistratova
O S
OS
Sukhikh
G T
GT
D002462:Cell Membrane / Q000201:enzymology; D005434:Flow Cytometry; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D013081:Sperm Motility / Q000502:physiology*; D013737:Testis / Q000201:enzymology
D007527:Isoenzymes; D007703:Peptidyl-Dipeptidase A