title: Genotypic diversity and antibiotic susceptibility of Acinetobacter baumannii isolates in a Bulgarian hospital.
abstract: A set of 18 Acinetobacter baumannii isolates, collected prospectively in a Bulgarian hospital during episodes of increased A. baumannii occurrence during 2000-2002, was investigated for genotypic diversity and antibiotic susceptibility. Four genotypes were identified by amplified fragment length polymorphism genomic fingerprinting, one of which (type 1) accounted for 13 isolates, indicating that a specific strain was predominant. The single isolate allocated to type 2 was identified to European clone I. All isolates were resistant to multiple antibiotics, but most retained susceptibility to tobramycin and colistin, and all except one were susceptible to imipenem.
authors.affiliation: Department of Clinical Microbiology, Military Medical Academy, Sophia, Bulgaria.
authors.forename: R
authors.initials: R
authors.lastname: Dobrewski
authors.forename: E
authors.initials: E
authors.lastname: Savov
authors.forename: A T
authors.initials: AT
authors.lastname: Bernards
authors.forename: M
authors.initials: M
authors.lastname: van den Barselaar
authors.forename: P
authors.initials: P
authors.lastname: Nordmann
authors.forename: P J
authors.initials: PJ
authors.lastname: van den Broek
authors.forename: L
authors.initials: L
authors.lastname: Dijkshoorn
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002031:Bulgaria; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D014644:Genetic Variation; D006772:Hospitals, Military; D006801:Humans; D008826:Microbial Sensitivity Tests; D012150:Polymorphism, Restriction Fragment Length; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial