title: Mucosal T-cell responses to enteric infection.
abstract: Although immunologists typically examine immune responses in peripheral lymphoid tissues, mucosal surfaces are the first sites at which most antigens are encountered. The role of lymphocytes in the gut-associated lymphoid tissue (GALT) in the production of secretory IgA has been well characterized. Although T cells of the GALT are located in areas likely to have a key role in cell-mediated immunity at mucosal surfaces, the ways in which these cells help defend against mucosal infection are only beginning to be understood. This review examines mucosal T-cell responses to enteric infection with bacteria, viruses, and parasites.
authors.affiliation: Mucosal Immunology Laboratory, Combined Program in Pediatric G.I. and Nutrition, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA. shiha@helix.mgh.harvard.edu
authors.forename: H N
authors.initials: HN
authors.lastname: Shi
authors.forename: C
authors.initials: C
authors.lastname: Nagler-Anderson