title: [Comparison in hydrophobic selectivity for two types of reversed-phase high performance liquid chromatography packing material].
abstract: Two types of novel reversed-phase packing materials were made by adding TiO2/ SiO2 (or ZrO2/SiO2) and octadecyltrichlorosilane into toluene with stirring and refluxing for 36 h. TiO2/SiO2 and ZrO2/SiO2 particles were prepared by a layer-by-layer self-assemble technique and consist of micrometer-sized silica spheres as cores and nanometer-sized zirconia or titania as surface coating. The carbon loading of C18-bonded TiO2/SiO2 was 11.51% and that of C18-bonded ZrO2/SiO2 was 9.62%. The hydrophobic selectivity and sensitivity were studied respectively and compared in details; the results showed that the packing supports both acted as true reversed chromatographic stationary phase with similar hydrophobic selectivity. The chromatographic behaviors of the two types of novel reversed-phase packing material were evaluated with nine aromatic compounds. The chromatographic studies showed that either of the packing materials would be a good choice to separate aromatic compounds, however, the selectivity of C18-bonded TiO2/SiO2 was a little better than that of C18-bonded ZrO2/SiO2.
authors.affiliation: Lanzhou Institute of Chemical Physics, the Chinese Academy of Sciences, Lanzhou 730000, China. gejin2003@126.com
authors.forename: Jin
authors.initials: J
authors.lastname: Ge
authors.forename: Hongli
authors.initials: H
authors.lastname: Zhang
authors.forename: Xiujuan
authors.initials: X
authors.lastname: Li
authors.forename: Shijun
authors.initials: S
authors.lastname: Shao
authors.forename: Yongmin
authors.initials: Y
authors.lastname: Li
authors.forename: Liren
authors.initials: L
authors.lastname: Chen