title: [The role of inflammation in the pathogenesis of late diabetic complications].
abstract: Chronic inflammation plays an important role in the development of diabetes and its late complications. Over nutrition, physical inactivity, stress, truncal obesity, dyslipidaemia, hypertension and smoking directly and indirectly activate the family of nuclear factor kappa B, the principal factor of inflammatory response. Hiperglycaemia and especially brittle diabetes affect not only metabolic abnormalities but also modulate cell and humoral immune response. There is good evidence that looking for novel risk factors for development and progression of late diabetic complications among inflammatory markers are needed. Progress in the study on etiopathogenesis of micro- and macro-angiopathy have clinical implications.
authors.affiliation: Klinika Chorób Wewnetrznych i Diabetologii Akademii Medycznej im. Karola Marcinkowskiego w Poznaniu. zozula@box43.pl
authors.forename: Dorota
authors.initials: D
authors.lastname: Zozulińska
mesh_terms: D000328:Adult; D000368:Aged; D015984:Causality; D015897:Comorbidity; D016207:Cytokines / Q000502:physiology; D048909:Diabetes Complications / Q000453:epidemiology / Q000503:physiopathology*; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007231:Infant, Newborn; D007249:Inflammation / Q000453:epidemiology*; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology; D009765:Obesity / Q000453:epidemiology; D012907:Smoking / Q000453:epidemiology
chemical_list: D016207:Cytokines