title: Early recovery from post-traumatic acute respiratory distress syndrome.
abstract: BACKGROUND
  To present and discuss the rationale and possible benefits of timely alveolar recruitment in early post-traumatic acute respiratory distress syndrome.
  
  
  METHODS
  A 17-year-old patient who had sustained blunt thoracic trauma presented with severe hypoxaemia on admission and whole body computed tomography showed pulmonary contusion and substantial bilateral atelectasis. Oxygenation and lung mechanics did not improve with low tidal volume ventilation using high positive end-expiratory pressures (PEEPs). Therefore we applied an alveolar recruitment manoeuvre 7 h after admission. After alveolar recruitment, PEEP was titrated to the lowest level which prevented alveolar derecruitment.
  
  
  RESULTS
  Oxygenation and lung compliance improved rapidly and aeration of the entire lung was confirmed by computed tomography 27 h after the recruitment manoeuvre. The patient recovered completely and was discharged after 17 days.
  
  
  CONCLUSIONS
  Although robust evidence is still lacking, several lines of evidence suggest potential benefits of timely alveolar recruitment. Patients with early post-traumatic respiratory failure seem to most readily respond to alveolar recruitment manoeuvres and could thus benefit from the gain in functional lung volume and oxygenation. Moreover the probability of ventilator associated complications may be reduced.
authors.affiliation: Department of Anaesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany. andreas.reske@medizin.uni-leipzig.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Reske
authors.forename: Matthias
authors.initials: M
authors.lastname: Seiwerts
authors.forename: Alexander
authors.initials: A
authors.lastname: Reske
authors.forename: Udo
authors.initials: U
authors.lastname: Gottschaldt
authors.forename: Dierk
authors.initials: D
authors.lastname: Schreiter
mesh_terms: D000293:Adolescent; D001929:Brain Edema / Q000209:etiology; D003288:Contusions / Q000150:complications; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008170:Lung Compliance; D055370:Lung Injury; D008297:Male; D010100:Oxygen / Q000032:analysis; D011175:Positive-Pressure Respiration; D001261:Pulmonary Atelectasis / Q000150:complications; D020127:Recovery of Function; D012128:Respiratory Distress Syndrome / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D013990:Tidal Volume; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000503:physiopathology
chemical_list: D010100:Oxygen