title: A new model for translational regulation of specific mRNAs.
abstract: Recently, RNA helicase A (RHA) has been shown to facilitate translation of specific mRNAs by recognizing and binding to a complex structure at their 5' end known as the post-transcriptional control element. This implicates RHA, a member of the DEXD/H-box protein superfamily, in linking transcription and translation of a specific class of retroviral and cellular mRNAs. This exciting finding suggests a new mechanism for the regulation of the translation of specific transcripts.
authors.affiliation: Department of Biology and DBRI, McGill University, 1205 Avenue Dr. Penfield, Montréal, Québec H3A 1B1, Canada.
authors.forename: Gritta
authors.initials: G
authors.lastname: Tettweiler
authors.forename: Paul
authors.initials: P
authors.lastname: Lasko
mesh_terms: D008957:Models, Genetic; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics*
chemical_list: D012333:RNA, Messenger