title: Acanthamoeba keratitis due to Acanthamoeba genotype T4 in a non-contact-lens wearer in Turkey.
abstract: An otherwise healthy 22-year-old man presented with Acanthamoeba keratitis (AK) in the right eye. He was not a contact lens wearer and had no history of corneal trauma. The Acanthamoeba strain isolated from a corneal scraping was identified as morphological group II and genotype T4. Three more Acanthamoeba strains isolated from sites of possible human contact with acanthamoebae in the same geographical region, including a lens storage case, tap water and soil, were subjected to morphological and molecular biological identification. Whereas the strain from tap water also exhibited genotype T4, the two other isolates were identified as morphological group I and genotype T9. To the best of our knowledge, this is the first study identifying an AK-causing Acanthamoeba strain in Turkey and the first isolation of genotype T9 in this country.
authors.affiliation: Department of Parasitology, Adnan Menderes University Medical Faculty, Aydin, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Ertabaklar
authors.forename: Meral
authors.initials: M
authors.lastname: Türk
authors.forename: Volkan
authors.initials: V
authors.lastname: Dayanir
authors.forename: Sema
authors.initials: S
authors.lastname: Ertuğ
authors.forename: Julia
authors.initials: J
authors.lastname: Walochnik
mesh_terms: D000048:Acanthamoeba / Q000145:classification* / Q000235:genetics*; D015823:Acanthamoeba Keratitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001550:Benzamidines / Q000627:therapeutic use; D001645:Biguanides / Q000627:therapeutic use; D003261:Contact Lenses; D004202:Disinfectants / Q000627:therapeutic use; D015725:Fluconazole / Q000627:therapeutic use; D005838:Genotype; D006801:Humans; D008297:Male; D009355:Neomycin / Q000627:therapeutic use; D012307:Risk Factors; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D001550:Benzamidines; D001645:Biguanides; D004202:Disinfectants; C031233:polihexanide; C046651:propamidine isethionate; D015725:Fluconazole; D009355:Neomycin