title: [Clinical features and treatment in Cushing's disease. 18 cases].
abstract: We report a retrospective study about 18 Cushing's diseases in the department of endocrinology at Charles Nicolle hospital in 24 years. The mean age was 33.7 years with a male-female ratio of 4/14. Diagnosis was established on adrenocorticotropin hormone analysis and pituitary imaging. Transsphenoidal adenomectomy was released in 8 cases of Cushing's disease, it was successful in 5 patients (62.5%). Bilateral adrenalectomy was performed in three cases.
authors.affiliation: Service de Médecine Interne A, Endocrinlolgie, Diabétologie, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Héla
authors.initials: H
authors.lastname: Cheikhrouhou
authors.forename: Karima
authors.initials: K
authors.lastname: Khiari
authors.forename: Insaf
authors.initials: I
authors.lastname: Hadj Ali
authors.forename: Lotfi
authors.initials: L
authors.lastname: Chérif
authors.forename: Néjib
authors.initials: N
authors.lastname: Ben Abdallah
mesh_terms: D000236:Adenoma / Q000097:blood / Q000175:diagnosis / Q000601:surgery; D000293:Adolescent; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D047748:Pituitary ACTH Hypersecretion / Q000097:blood / Q000175:diagnosis* / Q000601:surgery*; D010902:Pituitary Gland / Q000000981:diagnostic imaging; D010911:Pituitary Neoplasms / Q000097:blood / Q000175:diagnosis / Q000601:surgery; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000324:Adrenocorticotropic Hormone