title: [Concentration of interleukine-8 in tears in patients with cystic fibrosis].
abstract: OBJECTIVE
  To evaluate IL-8 concentration in tears fluid in cystic fibrosis patients.
  
  
  METHODS
  Tears samples were collected from 18 CF Patients and 18 normal controls. Cytokine level was determined by ELISA.
  
  
  RESULTS
  A significant increase of IL-8 concentration in tears fluid was found in CF patients compared with controls.
  
  
  CONCLUSIONS
  Increase IL-8 concentration in tears fluid in CF patients suggests a role of immunologic processes in the pathogenesis of the ocular changes, and may be a marker of the inflammatory status in ocular surface in cystic fibrosis.
authors.affiliation: Kliniki Okulistyki Dzieciecej, Akademii Medycznej w Białymstoku.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mrugacz
authors.forename: Beata
authors.initials: B
authors.lastname: Zelazowska
authors.forename: Alina
authors.initials: A
authors.lastname: Bakunowicz-Lazarczyk
authors.forename: Alina
authors.initials: A
authors.lastname: Minarowska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Wysocka
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000032:analysis; D002648:Child; D003550:Cystic Fibrosis / Q000276:immunology / Q000378:metabolism*; D005123:Eye / Q000276:immunology; D005260:Female; D006801:Humans; D016209:Interleukin-8 / Q000032:analysis*; D008297:Male; D012016:Reference Values; D013666:Tears / Q000737:chemistry*
chemical_list: D015415:Biomarkers; D016209:Interleukin-8