title: Guglielmi detachable coils versus matrix coils: a comparison of the immediate posttreatment results of the embolization of 364 cerebral aneurysms in 307 patients: a single-center, single-surgeon experience.
abstract: BACKGROUND
  Matrix coils are based on Gugliemi detachable coils (GDC) but are covered with polyglycolic/polylactic acid. We present our experience regarding the immediate posttreatment results of aneurysm embolization using the 2 coil systems.
  
  
  METHODS
  We embolized 219 aneurysms in 187 patients with the use of GDCs and 145 aneurysms in 120 patients with the use of Matrix coils. Age, sex distribution, unruptured aneurysm cases, and multiple aneurysm cases were similar in the 2 groups. The percentage of patients in severe clinical condition was significantly higher in the Matrix group. The mean aneurysm size was slightly larger in the GDC group but the mean neck size was larger in the Matrix group.
  
  
  RESULTS
  Satisfactory occlusion (at least 90%) was achieved in 95.9% of GDC-treated aneurysms and in 98.6% of Matrix-treated aneurysms. Procedure-related complications occurred in 19.6% of GDC procedures and in 15.6% of the Matrix ones resulting in procedure-related mortality and morbidity of 3.7% and 2.7% for the GDC group and 2.5% and 1.7% for the Matrix group. In the GDC group, outcome was good (modified Rankin Scale 0-2) in 92.6% of patients with unruptured aneurysms, in 82.6% of patients with Hunt and Hess grade I-III, and in 20.5% of those with Hunt and Hess grade of IV-V. The respective figures were 95%, 85.7%, and 22.7% in the Matrix group.
  
  
  CONCLUSIONS
  In our series, Matrix coils have yielded slightly better results regarding satisfactory occlusion rate and clinical outcome but these differences are not statistically significant and probably reflect our increased experience in aneurysm embolization during the period we used Matrix coils.
authors.affiliation: Neurosurgical Department, Papanikolaou General Hospital, Thessaloniki, Greece. vkats@iname.com
authors.forename: V
authors.initials: V
authors.lastname: Katsaridis
authors.forename: C
authors.initials: C
authors.lastname: Papagiannaki
authors.forename: C
authors.initials: C
authors.lastname: Violaris
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000628:therapy*; D020099:Coated Materials, Biocompatible; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage / Q000628:therapy
chemical_list: D020099:Coated Materials, Biocompatible; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid