Unexpected multifunctional effects of methylated cyclodextrins in a palladium charcoal-catalyzed Suzuki-Miyaura reaction.
[reaction: see text] Native and modified cyclodextrins (CDs) have shown polyvalent properties in a biphasic Pd/C-catalyzed Suzuki-Miyaura reaction. In addition to their mass transfer ability, the CDs favored the dispersion of the catalyst in water. With the randomly methylated CDs (RaMe-beta-CD), the gains of initial activities were multiplied by factors between 3.8 and 343 depending on the nature of the substrates. The reusability of the system was also demonstrated.
Cassez
Andy
A
Laboratoire de Physico-Chimie des Interfaces et Applications, FRE CNRS 2485, Fédération Chevreul FR CNRS 2638, Faculté des Sciences Jean Perrin, Université d'Artois, rue Jean Souvraz, S.P.18-62307 LENS Cédex, France.
Ponchel
Anne
A
Hapiot
Frédéric
F
Monflier
Eric
E
D002384:Catalysis; D003505:Cyclodextrins / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D003505:Cyclodextrins; D010165:Palladium