Langerhans cell histiocytosis on the penis: a case report.
BACKGROUND
Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs. A few cases of Langerhans cell histiocytosis on the penis have been reported in the literature. We present a case of Langerhans cell histiocytosis on the penis and review the similar cases in the literature.


METHODS
The patient was a 13-year-old boy who had a history of lymph node, femur bone, and pituitary-thalmic axis lesions from Langerhans cell histiocytosis who noticed a painful nodule on the prepuce of his penis. The histological and immunohistochemical examination fulfilled the criteria of Langerhans cell histiocytosis.


CONCLUSIONS
We herein describe the case reported of Langerhans cell histiocytosis on the penis.
Hagiuda
Jun
J
Department of Urology, Saitama Medical University, Saitama, Japan. junhagi@hotmail.com
Ueno
Munehisa
M
Ashimine
Satoshi
S
Kuroda
Isao
I
Ishizawa
Keisuke
K
Deguchi
Nobuhiro
N
D000293:Adolescent; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D010409:Penile Diseases / Q000473:pathology*