[Predisposing risk factors that participate in neonatal sepsis mortality rate].
BACKGROUND
Neonatal sepsis is a frequent diagnosis in neonatal intensive care units and has been associated with a high mortality rate.


OBJECTIVE
To determine the possible association between various risk factors and neonatal sepsis mortality rate.


METHODS
Cohort case control.


METHODS
Two hundred medical records of newborns discharged from a neonatology unit, from January 1998 to June 2002, with a neonatal sepsis diagnosis were reviewed.


RESULTS
There was significance in birth weight of 1000 g or less, vein dissection for insertion of central venous catheter, gestational age of 30 weeks or less, and presence of mechanical ventilatory assistance (p < 0.01). Total parenteral nutrition also reached significance but as protective factor (OR: 0.15, CI 95% 0.07 - 0.31) (p < 0.001). The multivariate analysis displayed similar results, except birth weight (p < 0.01).


CONCLUSIONS
The above mentioned risk factors should be prevented in as much as possible. A factor to prevent mortality is total parenteral nutrition which should be always employed in cases where this is feasible.
Tapia-Rombo
Carlos Antonio
CA
Servicio de Neonatología, Unidad Mèdica de Alta Especialidad (UMAE), Dr. Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social Mexico DF, México. tapiachar@yahoo.com.mx
Cortés-Sauza
Jorge
J
Saucedo-Zavala
Victor Joel
VJ
Cuevas-Urióstegui
María Luisa
ML
D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D018805:Sepsis / Q000401:mortality*