title: Sulfanyl radical promoted C4'-C5' bond scission of 5'-oxo-3',4'-didehydro-2',3'-dideoxynucleosides.
abstract: Treatment of C5'-aldehydes, under mildly basic conditions leads to the formation of 3',4'-didehydroaldehydes, and furfural. Sulfanyl radical addition eventually gives rise to the lactones, through C4'-C5' bond scission of the 1,2-dioxetane intermediates.
authors.affiliation: ISOF, Consiglio Nazionale delle Ricerche, Via P. Gobetti 101, 40129 Bologna, Italy.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Navacchia
authors.forename: Pier Carlo
authors.initials: PC
authors.lastname: Montevecchi
mesh_terms: D015224:Dideoxynucleosides / Q000737:chemistry*; D005609:Free Radicals; D012997:Solvents; D013696:Temperature; D013997:Time Factors
chemical_list: D015224:Dideoxynucleosides; D005609:Free Radicals; D012997:Solvents