title: Leiomyosarcoma of the uterus with intravascular tumor extension and pulmonary tumor embolism.
abstract: We report the case of a 48-year-old woman presenting with recurrent uterine leiomyosarcoma (LMS) associated with right iliac vein and inferior vena cava (IVC) invasion and left lower lobe pulmonary tumor embolus. Because the prognosis and treatment differ from that of thrombotic pulmonary emboli, the differentiating imaging characteristics of intravascular tumor embolism are reviewed. To our knowledge, only two other cases of intravenous uterine leiomyosarcomatosis have been described in the existing literature, and this is the first reported case of the entity with associated intravascular tumor embolism.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Douglas K
authors.initials: DK
authors.lastname: McDonald
authors.forename: Sanjeeva P
authors.initials: SP
authors.lastname: Kalva
authors.forename: Chieh-Min
authors.initials: CM
authors.lastname: Fan
authors.forename: Aleksandr
authors.initials: A
authors.lastname: Vasilyev
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007084:Iliac Vein / Q000000981:diagnostic imaging; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000150:complications* / Q000175:diagnosis; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology*; D035583:Rare Diseases; D014057:Tomography, X-Ray Computed / Q000379:methods; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology*; D019043:Vascular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000556:secondary; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging