title: Doppler sonographic evaluation of effect of treatment with infliximab (Remicade) for rheumatoid arthritis.
abstract: Synovial vascularization in the knee joints of six patients with rheumatoid arthritis who were treated with infliximab was evaluated by Doppler sonography. Power Doppler sonography demonstrated a significant reduction of color flow signals (P < 0.05), and spectral Doppler sonography demonstrated a significant increase in vascular resistance (P < 0.05) at week 6 (after three injections) evaluation of the therapy. A significant decrease in the number of tender joints (P < 0.05) and C-reactive protein value (P < 0.05) was also observed in these patients.
authors.affiliation: Division of Rheumatology, Ohta Nishinouchi Hospital, 2-5-20 Nishinouchi, Koriyama, 963-8558, Japan. junior@fmu.ac.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Ai
authors.initials: A
authors.lastname: Sato
authors.forename: Yukio
authors.initials: Y
authors.lastname: Yamadera
authors.forename: Isao
authors.initials: I
authors.lastname: Takeda
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanno
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Ohguchi
authors.forename: Tomoe
authors.initials: T
authors.lastname: Nishimaki
authors.forename: Reiji
authors.initials: R
authors.lastname: Kasukawa