title: Relationship between meconium staining, umbilical cord plasma motilin level and infantile colic.
abstract: OBJECTIVE
  To assess the effects of meconium-stained amniotic fluid and umbilical cord plasma motilin levels on the development of infantile colic.
  
  
  METHODS
  One hundred forty pregnant women referred to our department for labor care were enrolled in the study. All subjects were laboring women with singleton, vertex-presenting fetuses, with a gestational age of > or = 36 weeks. After each infant with meconium-stained amniotic fluid was born, the following 2 infants without meconium were selected as controls. Umbilical cord plasma motilin levels were measured in 47 infants with meconium-stained amniotic fluid and 93 infants with no meconium. At the end of the third month of the infants' lives, the development of infantile colic was evaluated. Umbilical cord serum specimens were collected from 45 infants with colic and 95 infants without colic. Statistics included Student's t, chi2 and Mann-Whitney U tests, as appropriate. Multivariate analysis was performed.
  
  
  RESULTS
  There was no correlation between the presence of meconium-stained amniotic fluid and the development of infantile colic. No association was found between umbilical cord plasma motilin levels and the development of infantile colic. Neonatal intensive care unit admission was found to be a significant risk factor for the development of infantile colic.
  
  
  CONCLUSIONS
  Meconium-stained amniotic fluid and umbilical cord plasma motilin levels do not affect the development of infantile colic.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Inonu University, 44069-Malatya, Turkey. mmeydanli@inonu.edu.tr
authors.forename: M Mutlu
authors.initials: MM
authors.lastname: Meydanli
authors.forename: Yaprak
authors.initials: Y
authors.lastname: Engin-Ustün
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Ustün
authors.forename: Denizhan
authors.initials: D
authors.lastname: Deniz
authors.forename: Ismail
authors.initials: I
authors.lastname: Temel
authors.forename: Serpil
authors.initials: S
authors.lastname: Firat
mesh_terms: D000653:Amniotic Fluid / Q000378:metabolism; D016022:Case-Control Studies; D003085:Colic / Q000209:etiology*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008470:Meconium; D009037:Motilin / Q000097:blood*; D011247:Pregnancy; D012307:Risk Factors
chemical_list: D009037:Motilin