title: Summary of probiotic activities of Bifidobacterium lactis HN019.
abstract: The bacterium, Bifidobacterium lactis HN019, has been studied for a variety of traits important to its ability to function as a probiotic. Publications documenting identity, safety, antipathogenic effects, immune enhancement, and intestinal colonization are reviewed. Most studies documenting immune effects are short term in duration (< or =6 wk feeding periods), so longer term trials would be useful to determine to what extent effects are sustained. One year-long trial feeding both galacto-oligosaccharides and HN019 in children 1 to 3 years of age provided evidence for improved growth and reduction in infection incidence. HN019 is a well-characterized probiotic strain with documented probiotic effects of meaningful magnitude especially in the area of immune system modulation.
authors.affiliation: Dairy and Food Culture Technologies, 7119 S. Glencoe Ct, Centennial, CO 80122, USA. mes@mesanders.com
authors.forename: Mary Ellen
authors.initials: ME
authors.lastname: Sanders
mesh_terms: D000818:Animals; D001644:Bifidobacterium / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification; D019587:Dietary Supplements / Q000382:microbiology; D005767:Gastrointestinal Diseases / Q000276:immunology / Q000628:therapy*; D005772:Gastrointestinal Transit; D006801:Humans; D008892:Milk / Q000276:immunology; D019936:Probiotics / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use