Summary of probiotic activities of Bifidobacterium lactis HN019.
The bacterium, Bifidobacterium lactis HN019, has been studied for a variety of traits important to its ability to function as a probiotic. Publications documenting identity, safety, antipathogenic effects, immune enhancement, and intestinal colonization are reviewed. Most studies documenting immune effects are short term in duration (< or =6 wk feeding periods), so longer term trials would be useful to determine to what extent effects are sustained. One year-long trial feeding both galacto-oligosaccharides and HN019 in children 1 to 3 years of age provided evidence for improved growth and reduction in infection incidence. HN019 is a well-characterized probiotic strain with documented probiotic effects of meaningful magnitude especially in the area of immune system modulation.
Sanders
Mary Ellen
ME
Dairy and Food Culture Technologies, 7119 S. Glencoe Ct, Centennial, CO 80122, USA. mes@mesanders.com
D000818:Animals; D001644:Bifidobacterium / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification; D019587:Dietary Supplements / Q000382:microbiology; D005767:Gastrointestinal Diseases / Q000276:immunology / Q000628:therapy*; D005772:Gastrointestinal Transit; D006801:Humans; D008892:Milk / Q000276:immunology; D019936:Probiotics / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use