Long-term safety of cardiac magnetic resonance imaging performed in the first few days after bare-metal stent implantation.
OBJECTIVE
To investigate the long-term safety of cardiac magnetic resonance imaging (CMR) performed one to seven days after coronary artery stent (bare metal) implantation.


METHODS
We analyzed 119 consecutive patients with acute myocardial infarction (MI) who underwent emergency coronary stent implantation with a bare-metal stent. CMR using a 1.5T scanner was performed on 51 patients (42.9%) at a mean of 2.7+/-3.1 days after stent implantation (CMR+ group), and the remaining 68 patients (57.1%) served as controls (CMR- group). The patients were followed up to six months for major adverse cardiac events.


RESULTS
The average stent size was 3.3+/-0.5x18.4+/-6.7 mm, and 86% of the stents were made of 316L stainless steel. There were no significant differences between the CMR+ and CMR- groups in terms of infarct features, angiographic findings, or stent characteristics. Over a mean follow-up of 4.4+/-2.1 months, 12 patients (10.1%) had 16 events (13.4%). Two patients had adverse events after early MRI scan (4.3%), a rate that is lower than the event rate in the patients who did not undergo MRI (16%, P=0.04), and one of the two events was clearly not MRI related.


CONCLUSIONS
CMR on a 1.5T scanner can be safely performed within one to seven days after coronary bare-metal stent implantation and is not associated with an increased risk of adverse clinical cardiac outcomes. In the light of accumulating data, the guidelines by stent manufacturers should be revised.
Syed
Mushabbar A
MA
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA.
Carlson
Karen
K
Murphy
Mandy
M
Ingkanisorn
W Patricia
WP
Rhoads
Kenneth L
KL
Arai
Andrew E
AE
D000368:Aged; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D023903:Coronary Restenosis / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000009:adverse effects*; D008297:Male; D008670:Metals; D008875:Middle Aged; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects*; D016896:Treatment Outcome
D008670:Metals