Addiction and arousal: alternative roles of hypothalamic peptides.
The importance of the lateral hypothalamus in the regulation of reward and motivation has long been recognized. However, the neuronal network involved in such a hypothalamic regulation of reward remains essentially unknown. Recently, hypocretin-containing neurons, a group of hypothalamic neurons known to be associated with the stability of arousal, have emerged as important structures in the control of brain reward function. This review summarizes a Mini-Symposium presented at the 2006 Annual Meeting of the Society for Neuroscience.
de Lecea
Luis
L
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA. llecea@stanford.edu
Jones
Barbara E
BE
Boutrel
Benjamin
B
Borgland
Stephanie L
SL
Nishino
Seiji
S
Bubser
Michael
M
DiLeone
Ralph
R
D000818:Animals; D001143:Arousal / Q000502:physiology*; D016739:Behavior, Addictive / Q000378:metabolism*; D006801:Humans; D007026:Hypothalamic Area, Lateral / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*
D009479:Neuropeptides