title: Deep morphea after vaccination in two young children.
abstract: A number of dermatoses have been reported to appear in close temporal or spatial relationship to the intramuscular injection of vaccines. We describe two young children who had morphea consistent with the deep morphea type (morphea profunda) that appeared at the site of a previous vaccination. Trauma has been implicated as an important trigger of morphea, both in children and in adults. Furthermore, vaccines might induce an immune response, which could lead to morphea in predisposed individuals.
authors.affiliation: Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain. atorrelo@aedv.es
authors.forename: Antonio
authors.initials: A
authors.lastname: Torrelo
authors.forename: José
authors.initials: J
authors.lastname: Suárez
authors.forename: Isabel
authors.initials: I
authors.lastname: Colmenero
authors.forename: Daniel
authors.initials: D
authors.lastname: Azorín
authors.forename: Antonio
authors.initials: A
authors.lastname: Perera
authors.forename: Antonio
authors.initials: A
authors.lastname: Zambrano
mesh_terms: D002675:Child, Preschool; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular / Q000009:adverse effects*; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage* / Q000009:adverse effects; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology; D014611:Vaccination / Q000009:adverse effects*
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D022542:Measles-Mumps-Rubella Vaccine