A randomized controlled trial of cognitive behavior therapy for borderline personality disorder: rationale for trial, method, and description of sample.
This paper describes the rationale for a randomized controlled trial, comparing cognitive behavior therapy in addition to treatment as usual with treatment as usual alone, for borderline personality disorder. Previous pioneering randomized controlled trials of psychotherapies have suffered from methodological weaknesses and have not always been reported clearly to allow adequate evaluation of either the individual study or comparisons across studies to be undertaken. We report on the recruitment and randomization, design, and conduct of an ongoing randomized controlled trial of one hundred and six patients with borderline personality disorder. Primary and secondary hypotheses and their planned analyses are stated. The baseline characteristics of 106 patients meeting diagnostic criteria for borderline personality disorder are described.
Davidson
Kate
K
Psychological Medicine, University of Glasgow. k.davidson@clinmed.gla.ac.uk
Tyrer
Peter
P
Gumley
Andrew
A
Tata
Philip
P
Norrie
John
J
Palmer
Stephen
S
Millar
Humera
H
Drummond
Leigh
L
Seivewright
Helen
H
Murray
Heather
H
Macaulay
Fiona
F
D000328:Adult; D000368:Aged; D001883:Borderline Personality Disorder / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011369:Professional-Patient Relations; D011569:Psychiatric Status Rating Scales; D012107:Research Design; D016896:Treatment Outcome