[Tall stature: some classical syndromes].
We describe the findings of XYY syndrome in the setting of encountering an individual with this particular condition in the endocrinology clinic. XYY syndrome is a relatively frequent if unfamiliar condition, which is characterized by taller than average height. The extra Y chromosome may play a role in determining the height of these individuals. From this case, a differential diagnosis of tall stature is outlined, in addition to a description of the principal syndromes associated with gigantism. These primarily include Klinefelter syndrome, Marfan syndrome, androgen resistance and growth hormone excess. These various entities are described from the point of view of their symptomatology, biology, pathophysiology and therapeutic characteristics.
Gusbin
N
N
ULg.
Verloes
A
A
Daly
A
A
Beckers
A
A
D013734:Androgen-Insensitivity Syndrome / Q000175:diagnosis / Q000628:therapy; D005877:Gigantism / Q000235:genetics* / Q000378:metabolism*; D019382:Human Growth Hormone / Q000378:metabolism; D006801:Humans; D007713:Klinefelter Syndrome / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D008297:Male; D008382:Marfan Syndrome / Q000175:diagnosis / Q000235:genetics / Q000628:therapy
D019382:Human Growth Hormone