High-grade hepatic mucosa-associated lymphoid tissue (MALT) lymphoma probably transformed from the low-grade gastric MALT lymphoma.
The Mucosa-associated lymphoid tissue (MALT) lymphoma, which was first described in 1983, is known to be caused by chronic Helicobacter pylori (HP) infection, which triggers lymphoid infiltration and formation of organized lymphoid tissue. In approximately two thirds of cases of MALT, the lymphoma has been observed to regress after treatment of H. pylori infection; this provides strong evidence of a causative role of HP in the etiology of MALT. We report a case of a 67-year-old female patient with a high-grade MALT lymphoma of the liver; this occurred six years after complete remission of a low-grade gastric MALT lymphoma and after complete eradication of H. pylori. there was no recurrence of the previous low-grade gastric MALT lymphoma. Based on radiological and pathologic findings, the high-grade MALT was considered to result from transformation of the low-grade gastric MALT lymphoma.
Chung
Yong Woo
YW
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Sohn
Joo Hyun
JH
Paik
Chang Hee
CH
Jeong
Jae Yoon
JY
Han
Dong Soo
DS
Jeon
Yong Cheol
YC
Oh
Young Ha
YH
D000368:Aged; D017809:Fatal Outcome; D005260:Female; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008113:Liver Neoplasms / Q000382:microbiology / Q000556:secondary*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000382:microbiology / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*