title: Intramuscular bleeding as a complication of anticoagulation treatment in a patient with systemic lupus erythematosus and antiphospholipid syndrome.
abstract: Thrombotic events account for significant morbidity and mortality among patients with antiphospholipid syndrome. The cornerstone of management includes long-term anticoagulation. However, the benefit of long-term anticoagulation must be weighed against the risk of bleeding complications. This article presents the case of a patient with systemic lupus erythematosus and antiphospholipid syndrome who experienced severe intramuscular hemorrhage as a complication of warfarin anticoagulation. This case emphasizes the importance of careful monitoring of anticoagulation treatment, and of recognizing a new differential diagnosis when dealing with a painful, swollen calf in the setting of lupus and antiphospholipid syndrome.
authors.affiliation: Mount Sinai Services, Queens Hospital Center and Mount Sinai School of Medicine, Jamaica, New York 11432, USA. rkucinsky@hotmail.com
authors.forename: Rastislav
authors.initials: R
authors.lastname: Kucinsky
authors.forename: Irene J
authors.initials: IJ
authors.lastname: Tan
authors.forename: Fred
authors.initials: F
authors.lastname: Rosner