[Special ginkgo extract in cases of vertigo: a systematic review of randomised, double-blind, placebo controlled clinical examinations].
BACKGROUND
The concept for the medical treatment of vertigo has changed over the last 30 years due to recognition of the dependence of the vertiginous sensation on vestibular compensation and the dependence of vestibular compensation on the state of vigilance.


METHODS
In this systematic review, experimental studies of the influence of the special ginkgo extract EGb 761 on vestibular compensation in animals and randomized, double-blind clinical studies of EGb 761 in vestibular and non-vestibular vertigo are described and critically evaluated.


RESULTS
The beneficial effect of EGb 761 on vestibular compensation has been demonstrated in preclinical and clinical studies.


CONCLUSIONS
Evidence of the efficacy of EGb 761 for the treatment of vertiginous syndromes is presented in the available studies.
Hamann
K-F
KF
HNO-Klinik, Klinikum rechts der Isar, München. vertigo.hamann@lrz.tum.de
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004353:Drug Evaluation, Preclinical / Q000706:statistics & numerical data / Q000639:trends*; D020441:Ginkgo biloba; D006801:Humans; D017063:Outcome Assessment, Health Care; D015990:Placebo Effect; D010936:Plant Extracts / Q000008:administration & dosage*; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data / Q000639:trends*; D016896:Treatment Outcome; D014717:Vertigo / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology*; D014722:Vestibule, Labyrinth / Q000187:drug effects* / Q000503:physiopathology*; D000096983:Ginkgo Extract
D010936:Plant Extracts; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract