Primary immunodeficiencies and susceptibility to parasitic infections.
Primary immunodeficiencies are important disorders because they typically cause severe illness in affected patients. In addition, these diseases provide a unique glimpse at the underpinnings of the immune system in humans. Susceptibility to infections, including those caused by parasites, is a hallmark of these immune defects. Understanding the association between primary immunodeficiencies and parasitic infections will likely improve our grasp on the mechanisms of defense against these pathogens.
Subauste
C S
CS
Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0560, USA. carlos.subauste@uc.edu
D004198:Disease Susceptibility / Q000276:immunology*; D020022:Genetic Predisposition to Disease; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D007153:Immunologic Deficiency Syndromes / Q000145:classification / Q000175:diagnosis / Q000276:immunology*; D010272:Parasitic Diseases / Q000453:epidemiology / Q000276:immunology* / Q000469:parasitology