The effect on creatinine kinase activity of freezing plasma from healthy foals.
OBJECTIVE
To assess the stability of creatine kinase (CK) activity in plasma collected from healthy foals and frozen at -20 degrees C for up to 12 weeks.


METHODS
Samples of venous blood drawn from 25 foals were analysed for CK activity soon after collection, and again after 1 and 12 weeks of freezing at -20 degrees C.


RESULTS
CK activity decreased (p<0.001) between Week 0 and Week 1 and between Week 0 and Week 12.


CONCLUSIONS
Decreases in CK activity were statistically significant but clinically insignificant.
Forsyth
S F
SF
Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand. S.F.Forsyth@massey.ac.nz
Lopez-Villalobos
N
N
Rogers
C W
CW
D000818:Animals; D000831:Animals, Newborn; D003402:Creatine Kinase / Q000378:metabolism*; D005615:Freezing; D006736:Horses / Q000378:metabolism*; D010949:Plasma / Q000201:enzymology*; D013048:Specimen Handling / Q000379:methods / Q000662:veterinary; D013997:Time Factors
D003402:Creatine Kinase