Acquisition of Helicobacter pylori infection in rhesus macaques is most consistent with oral-oral transmission.
Socially housed rhesus monkeys rapidly acquired Helicobacter pylori infection, although the organism was rarely cultivated from saliva, feces, or the environment. Since the concentrations of H. pylori in vomit were compatible with what is known about the infectious dose, our results are most consistent with an oral-oral means of transmission.
Solnick
Jay V
JV
Center for Comparative Medicine, University of California, Davis, Davis, CA 95616, USA. jvsolnick@ucdavis.edu
Fong
Julie
J
Hansen
Lori M
LM
Chang
Kikuko
K
Canfield
Don R
DR
Parsonnet
Julie
J
D000818:Animals; D005243:Feces / Q000382:microbiology; D005260:Female; D050456:Fomites; D016481:Helicobacter Infections / Q000382:microbiology / Q000635:transmission*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006799:Housing, Animal; D008253:Macaca mulatta; D008297:Male