title: Metastatic gastrointestinal stromal tumor and hypercalcemia in a patient with ulcerative colitis.
abstract: A 45-year-old man suffering from intermittent rectal bleeding was diagnosed with ulcerative colitis involving the descending colon and rectum. After 2 years on ulcerative colitis treatment, he presented with metastatic gastrointestinal tumor, liver and peritoneal spread, and a pelvic mass. Interestingly, he was found to have significant hypercalcemia. He was treated with Imatinib with significant symptomatic and clinical response.
authors.affiliation: Department of Medicine, College of Medicine, Sultan Qaboos University, PO Box 35, Muscat 123, Oman. mansours@squ.edu.om
authors.forename: Mansour S
authors.initials: MS
authors.lastname: Al-Moundhri
authors.forename: Khaled
authors.initials: K
authors.lastname: Al-Thahli
authors.forename: Said
authors.initials: S
authors.lastname: Al-Kindy
authors.forename: Jamal
authors.initials: J
authors.lastname: Salam
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Rao
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001549:Benzamides; D003093:Colitis, Ulcerative / Q000150:complications* / Q000473:pathology; D046152:Gastrointestinal Stromal Tumors / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000150:complications* / Q000175:diagnosis; D000068877:Imatinib Mesylate; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary; D010879:Piperazines / Q000627:therapeutic use*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D012007:Rectum / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000068877:Imatinib Mesylate