title: A short enantioselective total synthesis of the phytotoxic lactone herbarumin III.
abstract: The phytotoxic lactone herbarumin III has been synthesized in 11% overall yield. The approach applied uses Keck's asymmetric allylation and Sharpless epoxidation to build the key fragment. Esterification with 5-hexenoic acid and a ring closing metathesis was used to arrive at the target.
authors.affiliation: Natural Products Chemistry Division, Regional Research Laboratory (CSIR), Jorhat, 785 006, Assam, India.
authors.forename: Joshodeep
authors.initials: J
authors.lastname: Boruwa
authors.forename: Naminita
authors.initials: N
authors.lastname: Gogoi
authors.forename: Nabin C
authors.initials: NC
authors.lastname: Barua
mesh_terms: D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007783:Lactones; C477617:herbarumin III