title: NIS/H2SO4-Silica: a mild and efficient reagent system for the hydrolysis of thioglycosides.
abstract: Chemoselective hydrolysis of a variety of thioglycosides in the presence of a wide range of protecting groups has been achieved by using N-iodosuccinimide and H(2)SO(4) immobilized on silica in good to excellent yields.
authors.affiliation: Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India.
authors.forename: Somnath
authors.initials: S
authors.lastname: Dasgupta
authors.forename: Bimalendu
authors.initials: B
authors.lastname: Roy
authors.forename: Balaram
authors.initials: B
authors.lastname: Mukhopadhyay
mesh_terms: D006868:Hydrolysis; D007202:Indicators and Reagents; D012822:Silicon Dioxide / Q000737:chemistry*; D013388:Succinimides / Q000737:chemistry*; D013464:Sulfuric Acids / Q000737:chemistry*; D013865:Thioglycosides / Q000737:chemistry*
chemical_list: D007202:Indicators and Reagents; D013388:Succinimides; D013464:Sulfuric Acids; D013865:Thioglycosides; C008155:N-iodosuccinimide; D012822:Silicon Dioxide; C033158:sulfuric acid