Layer guided-acoustic plate mode biosensors for monitoring MHC-peptide interactions.
The transduction signals from the immobilisation of a class I heavy chain, HLA-A2, on a layer guided acoustic plate mode device, followed by binding of beta(2)-microglobulin and subsequent selective binding of a target peptide are reported.
Stanley
S M
SM
School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Nottingham, UK NG11 8NS.
Dodi
I A
IA
Evans
C R
CR
Paston
S J
SJ
Rees
R C
RC
Percival
C J
CJ
McHale
G
G
Newton
M I
MI
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D015789:HLA-A2 Antigen / Q000378:metabolism*; D006801:Humans; D033401:Microscopy, Acoustic; D017510:Protein Folding; D025941:Protein Interaction Mapping; D019809:Streptavidin / Q000378:metabolism*; D001613:beta 2-Microglobulin / Q000378:metabolism
D015789:HLA-A2 Antigen; D001613:beta 2-Microglobulin; D019809:Streptavidin