title: Managing the complexity of a dynamic biofilm.
abstract: BACKGROUND
  This article provides an overview of the history of oral microbiology, a discussion of dental plaque as both a microbial community and a biofilm, and a review of the measures available to control the oral microflora.
  
  
  METHODS
  The authors reviewed the literature related to oral microbiology and associated infectious diseases. They also examined articles that detailed the structure and physiology of biofilms, including dental plaque biofilms.
  
  
  CONCLUSIONS
  Biofilms cannot be eliminated. The pathogenic nature of the dental plaque biofilm can be diminished in the oral cavity by reducing the bioburden and effectively maintaining a normal oral flora via oral hygiene procedures that include daily toothbrushing, flossing and rinsing with an antimicrobial mouthrinse. An oral hygiene regimen that includes rinsing with an antimicrobial mouthrinse is a practical approach to the prevention and management of periodontal diseases. This strategy may have wider benefits when the link between periodontal disease and certain systemic diseases is considered.
  
  
  CONCLUSIONS
  An effective oral hygiene regimen can help control dental plaque biofilm and associated periodontal diseases.
authors.affiliation: Department of Pathology, West Virginia University, School of Medicine, Morgantown, USA. jthomas@hsc.wvu.edu
authors.forename: John G
authors.initials: JG
authors.lastname: Thomas
authors.forename: Lindsay A
authors.initials: LA
authors.lastname: Nakaishi
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D003773:Dental Plaque / Q000150:complications / Q000628:therapy*; D006801:Humans; D009055:Mouth / Q000382:microbiology*; D009910:Oral Hygiene