title: [Harmine induces apoptosis in human SGC-7901 cells].
abstract: OBJECTIVE
  [corrected] To investigate the effect of apoptosis induced in human SGC-7901 cells by Harmine.
  
  
  METHODS
  The effect of Harmine on human SGC-7901 cell survival and apoptosis was determined by MTT assay, light microscopy and flow cytometry. Cell genomic DNA was detected by agarose electrophoresis.
  
  
  RESULTS
  The survival of human SGC-7901 cells decreased; Apoptotic cells were observed by fluorescent microscope; FCM analysis showed that the peak of apoptosis increased. Typical DNA Ladder were detected in DNA agarose gel electrophoresis.
  
  
  CONCLUSIONS
  HM can induce apoptosis in human SGC-7901 cells.
authors.affiliation: Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Zhen-ya
authors.initials: ZY
authors.lastname: Song
authors.forename: Ji-ren
authors.initials: JR
authors.lastname: Liu
authors.forename: Xin-liang
authors.initials: XL
authors.lastname: Lu
authors.forename: Liang-jing
authors.initials: LJ
authors.lastname: Wang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor; D002470:Cell Survival; D005434:Flow Cytometry; D006247:Harmine / Q000494:pharmacology*; D006801:Humans; D032443:Peganum / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013274:Stomach Neoplasms / Q000473:pathology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D006247:Harmine