title: Ethnic differences in fasting glucose, insulin resistance and lipid profiles in obese adolescents.
abstract: Children and adolescents with obesity are increasingly referred to the pediatric endocrinology clinic at OU Children's Hospital for evaluation and initiation of preventive measures. During the summer of 2004 we conducted a retrospective review of cases to determine the prevalence of fasting insulin resistance and dyslipidemia; to study associations and differences due to ethnic background; and compare values with similar patients seen at four Indian Health Service clinics. We observed the highest prevalence of dyslipidemia in Caucasian youth. The prevalence of high fasting glucose and mean glucose values were higher in the obese Native American youth than in African Americans or Caucasians. The elevated glucose levels in young Native Americans may be associated with their increased risk for type 2 diabetes compared to other races; but Caucasians are more prone to dyslipidemia. Effective methods are needed to detect, prevent and treat diabetes and cardiovascular risk in children and adolescents.
authors.affiliation: Medical School, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. evan-moore@ouhsc.edu
authors.forename: Evan
authors.initials: E
authors.lastname: Moore
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Copeland
authors.forename: Don
authors.initials: D
authors.lastname: Parker
authors.forename: Christie
authors.initials: C
authors.lastname: Burgin
authors.forename: Piers R
authors.initials: PR
authors.lastname: Blackett
mesh_terms: D000293:Adolescent; D005006:Ethnicity; D006801:Humans; D007003:Hypoglycemia / Q000097:blood*; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood*; D009765:Obesity; D009825:Oklahoma; D012189:Retrospective Studies
chemical_list: D008055:Lipids