title: Verification of pacemaker automatic mode switching for the detection of atrial fibrillation and atrial tachycardia with Holter recording.
abstract: OBJECTIVE
  Verification of the accuracy of onset, offset, and duration of automatic mode switching (AMS) of pacemakers compared with onset and end of atrial fibrillation (AF) or atrial tachycardia (AT). Correct pacemaker diagnosis of atrial tachyarrhythmias (AA) is indispensable for reliable automatic prevention and intervention algorithms of AA.
  
  
  RESULTS
  Comparison was made of the AMS registration of the pacemaker-stored electrograms (EGMs) and the number and cumulative duration of these episodes with continuous 7-day Holter monitoring. Atrial sensitivity was kept at 0.5 mV and far field R-wave recognition in the atrial channel was excluded by blanking of this signal. Lead types were confined to leads with short-ring tip spacing (10-13.8 mm). During Holter monitoring, 18 of 57 included patients with standard reason for pacemaker implantation showed episodes of AF or AT. Cumulative duration of AF and AT from Holter was correctly interpreted by the pacemaker in 99.9% of the patients. All episodes of AF, as seen on the Holter recording, were recognized by the pacemaker (correlation 99.9%). During AF, multiple episodes of undersensing were detected. The number of AMS episodes was influenced by undersensing during AF. The influence of these short episodes of undersensing on the total duration of AF was trivial (cumulative duration of AF was 99.9% correct). In patients with AT without AF on Holter (n=7) and in contrast to the AF episodes, the cumulative AT duration did not correlate well (63%) with the Holter recordings. The number of AMS episodes in the setting of AT was influenced by the atrial tachycardia detection rate setting and the duration of the post-ventricular atrial blanking interval.
  
  
  CONCLUSIONS
  The total duration of AF is correctly represented by the total duration of AMS and can be considered a reliable measure of total AF duration. AT duration was poorly correlated with AMS duration. The number of mode switches does not reflect the number of episodes of AF/AT. Increased memory capacity allowing the storing of all EGMs triggered by the initiation of AF/AT would be the ideal setting with which to optimize the diagnostic performance of pacemakers.
authors.affiliation: Department of Cardiology, St Lucas Andreas Hospital, J. Tooropstraat 164, 1061 AE Amsterdam, The Netherlands. w.g.devoogt@planet.nl
authors.forename: Willem G
authors.initials: WG
authors.lastname: de Voogt
authors.forename: Norbert M
authors.initials: NM
authors.lastname: van Hemel
authors.forename: Arjan A
authors.initials: AA
authors.lastname: van de Bos
authors.forename: Juhani
authors.initials: J
authors.lastname: Koïstinen
authors.forename: Jules H
authors.initials: JH
authors.lastname: Fast
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000628:therapy*; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013612:Tachycardia, Ectopic Atrial / Q000175:diagnosis* / Q000628:therapy*; D013813:Therapy, Computer-Assisted / Q000379:methods*