title: Effect of Proview self-tonometry on pharmaceutical compliance.
abstract: OBJECTIVE
  To evaluate changes in patient compliance with medical treatment while using the Proview Eye Pressure Monitor.
  
  
  METHODS
  A crossover study design was used to compare the compliance of patients with established use of topical medication to lower intraocular pressure in the treatment of primary open-angle glaucoma. Thirty-two patients currently managed with latanoprost 0.005%, brimonidine 0.15%, travoprost 0.004% or bimatoprost 0.03% as monotherapy or in combination were randomly assigned to two study groups. Group 1 was instructed in the use of Proview Eye Pressure Monitor three times daily for 30 days as an adjunct to the glaucoma regimen. Group 2 was observed with no change in the patients' treatment regimen during this phase of study. A crossover occurred at 30 days. Compliance was monitored by assigning new bottles of topical medication during each phase of study. Bottles were weighed with a Mettler balance (Mettler Toledo Co.) at the initiation and completion of each phase. The changes in bottle-weight determined the amount of medication consumed by each patient for each phase of the study. The weights were analysed to estimate changes in compliance.
  
  
  RESULTS
  A paired samples Student t-test compared the consumed bottle weights with and without Proview Eye Pressure Monitor usage. No statistical significance or trend was identifiable (p = 0.98). Use of the Proview Eye Pressure Monitor did not significantly change compliance with adjunct eye drop medication.
  
  
  CONCLUSIONS
  The use of the Proview Eye Pressure Monitor use did not improve but appeared to hinder compliance with glaucoma treatment in this study.
authors.affiliation: Southern College of Optometry, Memphis, Tennessee, USA. clievens@sco.edu
authors.forename: Christopher W
authors.initials: CW
authors.lastname: Lievens
authors.forename: Pinakin
authors.initials: P
authors.lastname: Gunvant
authors.forename: James
authors.initials: J
authors.lastname: Newman
authors.forename: Michael
authors.initials: M
authors.lastname: Gerstner
authors.forename: Chad
authors.initials: C
authors.lastname: Simpson
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018592:Cross-Over Studies; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008875:Middle Aged; D009883:Ophthalmic Solutions; D010349:Patient Compliance; D011379:Prognosis; D011446:Prospective Studies; D014065:Tonometry, Ocular / Q000379:methods*
chemical_list: D000959:Antihypertensive Agents; D009883:Ophthalmic Solutions