A practical method for the synthesis of indolylaryl- and bisindolylmaleimides.
[reaction: see text] Indolylaryl and indolylheteroarylmaleimides, including bisindolylmaleimides, are easily prepared by the reaction of N-methylindole-3-glyoxylamide with methyl aryl acetates in the presence of potassium tert-butoxide in THF.
Roy
Sudipta
S
Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.
Roy
Sujata
S
Gribble
Gordon W
GW
D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008301:Maleimides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D007211:Indoles; D008301:Maleimides; C088060:bisindolylmaleimide