[Prevention of osteoporosis by foods and dietary supplements. Vitamin K and bone metabolism].
Many reports have indicated the significant correlation between low vitamin K intakes and the increased prevalence of osteoporotic fractures. The role of vitamin K in bone metabolism is assumed to be mediated by carboxylation of vitamin-K-dependent proteins. In addition, recent researches suggest the novel action of vitamin K(2) via nuclear receptors. The role of vitamin K in the prevention as well as the treatment of osteoporosis should be more emphasized.
Hosoi
Takayuki
T
National Center for Geriatrics and Gerontology, Department of Advanced Medicine.
D001842:Bone and Bones / Q000378:metabolism*; D006801:Humans; D010024:Osteoporosis / Q000517:prevention & control; D014812:Vitamin K / Q000494:pharmacology*
D014812:Vitamin K