Highly efficient oxidative amidation of aldehydes with amine hydrochloride salts.
A mild and efficient copper-catalyzed oxidative amidation of aldehydes was developed using amine HCl salts and tert-butyl hydroperoxide as an oxidant.
Yoo
Woo-Jin
WJ
Department of Chemistry, McGill University, Montreal, Quebec, Canada H3A 2K6.
Li
Chao-Jun
CJ
D000447:Aldehydes / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D007454:Iodides / Q000737:chemistry; D010084:Oxidation-Reduction
D000447:Aldehydes; D000577:Amides; D000588:Amines; D007454:Iodides; D003300:Copper; C073870:cuprous iodide