title: The diagnostic efficacy of FDG-PET in the local recurrence of hilar bile duct cancer.
abstract: OBJECTIVE
  It is frequently difficult to make an accurate diagnosis of the local recurrence of hilar bile duct cancer (HBC). We assessed the efficacy of fluorodeoxyglucose-positron emission tomography (FDG-PET) in diagnosing the local recurrence of HBC.
  
  
  METHODS
  Among 18 patients who had previously undergone resection of HBC, 5 were suspected of having a recurrence. These 5 patients were examined for recurrence by computed tomography (CT) and FDG-PET. A definitive diagnosis was determined either by pathological studies or by clinical follow-up.
  
  
  RESULTS
  Whereas CT showed a recurrent mass in only 1 patient, FDG-PET revealed the high uptake of FDG in all patients. Histopathological and/or cytological examinations confirmed the local recurrence of HBC in 4 patients. One false-positive result occurred in a patient with reflux cholangitis. One patient with a recurrent tumor was followed by FDG-PET after irradiation therapy. The high level of FDG uptake, which had been seen in that patient before irradiation, completely disappeared after treatment.
  
  
  CONCLUSIONS
  When used in combination with other modalities, FDG-PET offered useful information for the diagnosis of a local recurrence of HBC. This highly sensitive imaging approach also appeared to be useful for follow-up examination after irradiation therapy.
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Chikamoto
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Tsuji
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takamori
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Kanemitsu
authors.forename: Hideaki
authors.initials: H
authors.lastname: Uozumi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Hideo
authors.initials: H
authors.lastname: Baba
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D002761:Cholangitis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006500:Hepatic Duct, Common; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18