[Keratomycosis due to Cylindrocarpon lichenicola].
Two independent males acquired keratomycosis at a few months interval. The culturally proven pathogen was Cylindrocarpon lichenicola (C. Massal) D. Hawksworth. For one patient Clematis plants were suspected of source of infection. Both patients did not remember traumata; they had no contact with each other, and their residences were far apart. One patient was treated with voriconazole locally and systemically for 12 weeks, the other patient with amphotericin B locally for 6 weeks. Both treatment regimens were successful. Cylindrocarpon lichenicola is characterised by keratinolytic properties. Following molecular-genetic studies the pathogen was recently reclassified as Fusarium lichenicola.
Kaben
Ursula
U
Institut für Medizinische Mikrobiologie, Virologie und Krankenhaushygiene der Universität Rostock, Germany. ursula.kaben@uni-rostock.de
Beck
Ria
R
Tintelnot
Kathrin
K
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D039324:Clematis / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D005670:Fusarium / Q000145:classification; D006801:Humans; D006999:Hypocreales / Q000145:classification / Q000187:drug effects / Q000472:pathogenicity*; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D011743:Pyrimidines / Q000627:therapeutic use; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D065819:Voriconazole