title: COPI-mediated transport.
abstract: COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.
authors.affiliation: Biochemie Zentrum, University of Heidelberg, Im Neuenheimer Feld 328, D-69120, Heidelberg, Germany. julien.bethune@bzh.uni-heidelberg.de
authors.forename: J
authors.initials: J
authors.lastname: Béthune
authors.forename: F
authors.initials: F
authors.lastname: Wieland
authors.forename: J
authors.initials: J
authors.lastname: Moelleken
mesh_terms: D000818:Animals; D001692:Biological Transport; D022181:COP-Coated Vesicles / Q000378:metabolism*; D022163:Clathrin-Coated Vesicles / Q000378:metabolism*; D020755:Coat Protein Complex I / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology
chemical_list: D020755:Coat Protein Complex I