title: How does endothelin-1 cause a sustained increase in intracellular sodium and calcium which lead to hypertrophy?
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Murphy
authors.forename: David A
authors.initials: DA
authors.lastname: Eisner
mesh_terms: D000818:Animals; D006332:Cardiomegaly / Q000378:metabolism*; D019332:Endothelin-1 / Q000494:pharmacology*; D051381:Rats; D019831:Sodium-Calcium Exchanger / Q000378:metabolism*; D017923:Sodium-Hydrogen Exchangers / Q000378:metabolism*
chemical_list: D019332:Endothelin-1; D019831:Sodium-Calcium Exchanger; D017923:Sodium-Hydrogen Exchangers; C069139:growth factor-activatable Na-H exchanger NHE-1