G-protein signaling: a new branch in an old pathway.
A recent study provides evidence for a new branch of the yeast mating pathway in which a G-protein alpha subunit directly activates phosphatidylinositol 3-kinase at endosomes.
Bardwell
Lee
L
Department of Developmental and Cell Biology, University of California, Irvine, California 92697-2300, USA. bardwell@uci.edu
D011992:Endosomes / Q000201:enzymology*; D004789:Enzyme Activation / Q000502:physiology; D005656:Fungal Proteins / Q000378:metabolism; D044385:GTP-Binding Protein alpha Subunits / Q000235:genetics / Q000502:physiology*; D008954:Models, Biological; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D015003:Yeasts / Q000201:enzymology* / Q000235:genetics / Q000378:metabolism
D005656:Fungal Proteins; D044385:GTP-Binding Protein alpha Subunits; D019869:Phosphatidylinositol 3-Kinases