"Non-serotonergic" lateral superior olivary neurons of the neonatal mouse contain serotonin.
In mutant mice which have high serotonin (5-HT) levels perinatally, neurons in the lateral superior olive (LSO, which are not serotonergic), contain 5-HT transiently in the neonatal period of development. We determined that the same phenomenon occurs in non-genetically altered mice: LSO neurons were 5-HT-immunoreactive at postnatal days 1 and 8. These findings suggest accumulation of 5-HT in by LSO neurons during postnatal development.
Thompson
Ann M
AM
Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA. ann-thompson@ouhsc.edu
D000818:Animals; D000831:Animals, Newborn; D001306:Auditory Pathways / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D051379:Mice; D008809:Mice, Inbred C3H; D009474:Neurons / Q000378:metabolism*; D009847:Olivary Nucleus / Q000166:cytology / Q000254:growth & development / Q000378:metabolism*; D012701:Serotonin / Q000378:metabolism*; D014018:Tissue Distribution
D012701:Serotonin