Novel immobilization method of enzymes using a hydrophilic polymer support.
A novel immobilization of an enzyme with a hydrophilic polymer support in organic solvents has been developed utilizing the "polymer-incarcerated (PI) method", which has been used to immobilize metal catalysts; the kinetic resolution of secondary alcohols was found to proceed more smoothly using immobilized lipases (CALB) than free lipases.
Kobayashi
Juta
J
Graduate School of Pharmaceutical Sciences, The University of Tokyo, The HFRE Division, ERATO, Japan Science and Technology Agency, JST, Hongo, Tokyo, 113-0033, Japan.
Mori
Yuichiro
Y
Kobayashi
Shū
S
D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D004800:Enzymes, Immobilized / Q000737:chemistry*; D005656:Fungal Proteins; D008049:Lipase / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013379:Substrate Specificity; D014867:Water / Q000737:chemistry
D000438:Alcohols; D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D011108:Polymers; D014867:Water; D008049:Lipase; C431349:lipase B, Candida antarctica