title: Synovial sarcoma of the tendon and tendon sheath in a dog.
abstract: A 19.5-year-old male mongrel dog developed a progressive lameness and swelling around the right carpus. A tumor (6 x 3 x 3 cm) was found in the caudal of distal antebrachium of the right forelimb, including tendons of the superficial digital flexor muscle and deep digital flexor muscle. No joint destruction was observed. The tumor consisted of round and spindle cells arranged in a compact sheet. There were occasional slit-like spaces or lumina, and areas rich in collagen fibers giving an appearance of tendon tissues. Neoplastic cells gave a positive immunoreaction to vimentin, but negative reactions to antibodies against S-100 protein, cytokeratin and myoglobin. Based on these findings, this tumor was diagnosed as a synovial sarcoma generating from the tendon and tendon sheath, which is very uncommon in dogs.
authors.affiliation: Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
authors.forename: Jyoji
authors.initials: J
authors.lastname: Yamate
authors.forename: Mami
authors.initials: M
authors.lastname: Aota
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kuwamura
authors.forename: Takao
authors.initials: T
authors.lastname: Kotani
authors.forename: Terumasa
authors.initials: T
authors.lastname: Shimada
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005552:Forelimb; D008297:Male; D013584:Sarcoma, Synovial / Q000473:pathology / Q000662:veterinary*; D013710:Tendons / Q000473:pathology*