title: Layer guided-acoustic plate mode biosensors for monitoring MHC-peptide interactions.
abstract: The transduction signals from the immobilisation of a class I heavy chain, HLA-A2, on a layer guided acoustic plate mode device, followed by binding of beta(2)-microglobulin and subsequent selective binding of a target peptide are reported.
authors.affiliation: School of Biomedical and Natural Sciences, Nottingham Trent University, Clifton Lane, Nottingham, UK NG11 8NS.
authors.forename: S M
authors.initials: SM
authors.lastname: Stanley
authors.forename: I A
authors.initials: IA
authors.lastname: Dodi
authors.forename: C R
authors.initials: CR
authors.lastname: Evans
authors.forename: S J
authors.initials: SJ
authors.lastname: Paston
authors.forename: R C
authors.initials: RC
authors.lastname: Rees
authors.forename: C J
authors.initials: CJ
authors.lastname: Percival
authors.forename: G
authors.initials: G
authors.lastname: McHale
authors.forename: M I
authors.initials: MI
authors.lastname: Newton
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D015789:HLA-A2 Antigen / Q000378:metabolism*; D006801:Humans; D033401:Microscopy, Acoustic; D017510:Protein Folding; D025941:Protein Interaction Mapping; D019809:Streptavidin / Q000378:metabolism*; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D015789:HLA-A2 Antigen; D001613:beta 2-Microglobulin; D019809:Streptavidin