[Caenorhabditis elegans: in vivo study model of bacterial virulence].
The nematode Caenorhabditis elegans presents many advantages as a model system. The worm has recently emerged as a potentially useful tool for the study of host-pathogen interactions. This paper presents advantages and inconveniences of this model, the variety of bacterial pathogens studied, and its use to monitor virulence of Extraintestinal Escherichia coli strains.
Lavigne
J-P
JP
Laboratoire de bactériologie, virologie, parasitologie, CHU de Nîmes, groupe hospitalo-universitaire de Carémeau, place du Professeur-Robert-Debré, 30029 Nîmes cedex 09, France. jean-philippe.lavigne@univ-montp1.fr
Blanc-Potard
A-B
AB
Bourg
G
G
O'callaghan
D
D
Sotto
A
A
D000818:Animals; D001424:Bacterial Infections; D017173:Caenorhabditis elegans / Q000382:microbiology*; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000472:pathogenicity; D004927:Escherichia coli Infections; D006801:Humans; D015203:Reproducibility of Results; D014774:Virulence