title: Metabolic abnormalities and body fat redistribution in HIV-1 infected patients: the lipodystrophy syndrome.
abstract: A unique and unexpected syndrome consisting of metabolic abnormalities (hyperlipidaemia and insulin resistance) and body fat redistribution (central adiposity and peripheral fat wasting) has been reported with increasing frequency in HIV-1 infected patients, most of whom are receiving highly active antiretroviral therapies including HIV-1 protease inhibitors. This article reviews the clinical and laboratory characteristics, the pathogenesis, and the management of this syndrome.
authors.affiliation: Infectious Disease Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Martínez
authors.forename: J M
authors.initials: JM
authors.lastname: Gatell