title: Rhodococcus equi infection during treatment of a c-ANCA positive vasculitis: a case report.
abstract: Rhodococcus equi is a rare form of opportunistic infection in humans, more common in the immunocompromised. We present a case of pulmonary infection and subsequent cerebral abscess secondary to R. equi in a patient receiving immunosuppression for a c-ANCA positive vasculitis. Heightened awareness of R. equi infection is important when considering immunocompromised patients presenting with sepsis, especially those with cavitating pulmonary lesions and normal respiratory commensals on culture. Delays in diagnosis and treatment can cause increased patient morbidity and mortality.
authors.affiliation: Department of Renal Medicine, Doncaster Royal Infirmary, Thorne Road, Armthorpe Road, DN2 5LT, Doncaster, England.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Garthwaite
authors.forename: David J
authors.initials: DJ
authors.lastname: Border
authors.forename: Colin H
authors.initials: CH
authors.lastname: Jones
authors.forename: David P
authors.initials: DP
authors.lastname: Worth
mesh_terms: D000193:Actinomycetales Infections / Q000150:complications*; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001922:Brain Abscess / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications*; D016929:Rhodococcus equi / Q000472:pathogenicity*; D014657:Vasculitis / Q000188:drug therapy*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents