Pulmonary benign metastasizing leiomyoma: a report of 2 cases with different outcomes.
BACKGROUND
Benign metastasizing leiomyoma (BML) of the lung is a rare manifestation of metastasis from a uterine myoma, in which its benign characteristics are maintained. The majority of cases are asymptomatic.


METHODS
Case 1 responded to the classic treatment of oophorectomy, after which an improvement in symptoms was achieved. In case 2, however, symptoms appeared following oophorectomy and were treated with raloxifene.


CONCLUSIONS
These cases show the uncertainty that exists with respect to the evolution and treatment of symptomatic BML. Raloxifene is a therapeutic agent that has not been widely studied for this purpose but should be considered for inclusion in the arsenal of therapeutic options available.
Benetti-Pinto
Cristina Laguna
CL
Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas, Campinas, Brazil. crislag@sigmanet.com.br
Soares
Patrícia Magda
PM
Petta
Carlos Alberto
CA
De Angelo-Andrade
Liliana A L
LA
D000328:Adult; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D018231:Leiomyomatosis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology*; D010052:Ovariectomy; D020849:Raloxifene Hydrochloride / Q000627:therapeutic use; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000473:pathology*
D004965:Estrogen Antagonists; D020849:Raloxifene Hydrochloride