Malignant hyperthermia: advances in diagnostics and management.
Real-time monitoring of end-tidal carbon dioxide during anaesthesia aids in the early detection of malignant hyperthermia and the occurrence of a rapid increase in end-tidal carbon dioxide, associated with unexplained persistent tachycardia, well before the core temperature begins to rise. Should malignant hyperthermia occur, however, dantrolene permits the dependable reversal of skeletal muscle hypermetabolism.
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Service d'Accueil et d'Urgence, Hôpital R. Salengro, CHRU Lille, 59037 Lille Cedex, France. p-adnet@chru-lille.fr
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