Blood conservation in patients undergoing non-cardiac surgery.
Concerns about the safety, inventory, and cost of allogeneic blood have led to a renewed interest in blood conservation. Autologous blood collection techniques, including preoperative autologous donation, acute normovolemic hemodilution, and perioperative blood recovery are routinely used as alternatives to allogeneic transfusion. In the future, these techniques may be combined with pharmacological strategies, such as presurgical erythropoietin therapy or red cell substitutes, to reduce further the need for allogeneic blood.
Goodnough
L T
LT
Department of Medicine, Washington University School of Medicine, St Louis, MO 63110-1093, USA. goodnough@labmed.wustl.edu
Monk
T G
TG