[Dementia--genetic aspects].
Several prevalent, sporadic neurodegenerative disorders also occur as rare inherited variants. Mapping of the genes involved in rare variants of the disorders has contributed to elucidating pathogenetic pathways for several dementia disorders, and the increased knowledge creates a possibility for development of new molecular genetic methods for diagnostics and for the treatment of the different types of dementia. Although inherited dementia disorders are generally rare, a genetic basis should always be considered when facing a patient with a recently clinically diagnosed dementia disorder.
Lindquist
Suzanne Granhøj
SG
H:S Rigshospitalet, Neurocentret, Neurologisk Klinik, H:S Hukommelsesklinikken. granhojlindquist@gmail.com
Waldemar
Gunhild
G
Nielsen
Jørgen Erik
JE
D000544:Alzheimer Disease / Q000235:genetics; D003704:Dementia / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D006816:Huntington Disease / Q000235:genetics; D028361:Mitochondrial Diseases / Q000235:genetics; D025202:Molecular Diagnostic Techniques; D009154:Mutation