Electrophilic allylations and benzylations of indoles in neutral aqueous or alcoholic solutions.
[reaction: see text] Indoles are allylated and benzylated in moderate to quantitative yield when stirred with allyl and benzyl halides in 80% aqueous acetone in the presence of NH(4)HCO(3) at room temperature.
Westermaier
Martin
M
Department Chemie und Biochemie, Ludwig Maximilians Universität München, Butenandtstr. 5-13 (Haus F), 81377 München, Germany.
Mayr
Herbert
H