Carbon dioxide absorption: toxicity from sevoflurane and desflurane.
The degradation of volatile anaesthetics by desiccated carbon dioxide absorbents can result in adverse outcomes. Desiccated carbon dioxide absorbent reacting with desflurane can cause potentially life-threatening intraoperative carbon monoxide exposure; the reaction with sevoflurane can cause the formation of several toxic breakdown products, e.g. compound A. Compound A-related renal toxicity in humans is still a matter of controversy.
Bremerich
D H
DH
Klinik für Anesthesiologie, Intensivmedizin und Schmerztherapie, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany.
Dudziak
R
R
Behne
M
M