title: Goat paratuberculosis in Chile: first isolation and confirmation of Mycobacterium avium subspecies paratuberculosis infection in a dairy goat.
abstract: In October 2004, 41 goats > 2 years old from a Saanen dairy goat herd located in Purranque County, 10th Region, Chile, were sampled and tested for paratuberculosis. While collecting samples it was observed that several goats were thin and emaciated. One goat was sufficiently debilitated to warrant humane euthanasia. This animal was brought to the Veterinary School at the Universidad Austral de Chile for necropsy. The goat selected for necropsy was a 12-year-old doe. The animal showed classical clinical signs of caprine paratuberculosis: emaciation despite willingness to eat, dry and rough hair coat, and no evidence of diarrhea. Gross pathology and histopathology of the necropsied goat were consistent with paucibacillary paratuberculosis. Bacteriology, serology, and PCR confirmed the diagnosis. This is the first published report of goat paratuberculosis in Chile confirming a case of caprine paucibacillary paratuberculosis.
authors.affiliation: Instituto de Microbiologia, Facultad de Ciencias, Universidad Austral de Chile, Casilla 167, Valdivia, Chile. jkruze@uach.cl
authors.forename: Juan
authors.initials: J
authors.lastname: Kruze
authors.forename: Miguel
authors.initials: M
authors.lastname: Salgado
authors.forename: Enrique
authors.initials: E
authors.lastname: Paredes
authors.forename: Armin
authors.initials: A
authors.lastname: Mella
authors.forename: Michael T
authors.initials: MT
authors.lastname: Collins
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002677:Chile; D004251:DNA Transposable Elements / Q000235:genetics; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005243:Feces / Q000382:microbiology; D005260:Female; D015511:Goat Diseases / Q000382:microbiology* / Q000473:pathology; D006041:Goats; D007410:Intestinal Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D008892:Milk / Q000382:microbiology; D016927:Mycobacterium avium subsp. paratuberculosis / Q000235:genetics / Q000302:isolation & purification*; D010283:Paratuberculosis / Q000382:microbiology* / Q000473:pathology; D016133:Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D004251:DNA Transposable Elements; D004279:DNA, Viral