Rapid growth in infancy: balancing the interests of the child.
Low birth weight is associated with a number of immediate adverse consequences, and it has been assumed that "catch-up" growth is a "good thing" because "better" nutritional status is associated with greater childhood health and survival. The same thinking applies to infants who suffer malnutrition and growth faltering during weaning. Recent studies suggest that the rapid postnatal growth of babies is associated with an enhanced risk for obesity, diabetes, hypertension, cardiovascular disease and osteopenia in later life. If this is true, it has implications for our recommendations for infant feeding. Insights from evolutionary biology, life cycle theory, animal husbandry, epidemiology and comparative zoology suggest that the energetic feeding of underweight infants should be considered in the context of the whole life cycle and balance the interests of the child with its likely fortunes in adulthood. Before we revise our current recommendations, we must consider the meaning of catch-up growth, what it involves in terms of tissues gained (fat, muscle and bone) and to what degree association represents causation. In the meantime, it will be prudent to balance the short- and long-term interests of the child by endeavoring to (1) optimize maternal nutrition and health, to avoid low birth weight, (2) breast-feed ideally, (3) consider birth weight, gestation and future "nutritional environment" when making decisions about infant feeding, (4) use appropriate growth charts, (5) avoid excessive postnatal weight gain, (6) think about the whole life span and (7) extrapolate from animal studies cautiously.
Weaver
Lawrence T
LT
Division of Developmental Medicine, University of Glasgow, and Royal Hospital for Sick Children, Glasgow, Scotland. lweaver@clinmed.gla.ac.uk
D001903:Bottle Feeding; D001942:Breast Feeding; D002657:Child Development / Q000502:physiology*; D006128:Growth / Q000502:physiology; D006801:Humans; D007223:Infant; D041943:Infant Formula; D007227:Infant Nutritional Physiological Phenomena / Q000502:physiology*; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D039382:Maternal Nutritional Physiological Phenomena; D009752:Nutritional Status; D009765:Obesity / Q000503:physiopathology; D015430:Weight Gain / Q000502:physiology*