title: Observations on the management of Coats' disease: less is more.
abstract: BACKGROUND
  In this article we share our experience of treating various severities of Coats' disease and focus on optimal therapy for advanced disease.
  
  
  METHODS
  Retrospective chart review of 10 patients treated with varied techniques including intraocular surgery, cryopexy and/or laser photocoagulation.
  
  
  RESULTS
  Nine patients were male. At presentation the average age was 4.6 years (range 21 months-7 years), the average number of retinal quadrants involved with telangiectasia was 2.7 (range 1-4, median 3), eight of the 10 patients had retinal detachment, six of these being total, and all patients had macular involvement with either exudate or fibrosis. Average follow-up was 2.3 years (range 1-4.5 years). The best visual outcomes were observed in patients who presented with less severe disease. For example, the only four patients to maintain ambulatory vision all presented without total retinal detachment, two or fewer quadrants of retinal telangiectasia and a visual acuity better than light perception. No patient developed secondary angle closure glaucoma, and all patients have kept a cosmetically acceptable eye.
  
  
  CONCLUSIONS
  In this limited series, visual outcomes in the setting of advanced Coats' disease are largely dependent on disease severity and visual status at the time of presentation. Minimally invasive surgery with vitreous infusion through the pars plana, combined with external drainage of subretinal fluid together with cryotherapy and/or laser photocoagulation is sufficient to effect retinal re-attachment and prevent loss of the eye.
authors.affiliation: Department of Ophthalmology, McMaster University, 41-1967 Main St. W. Hamilton, Ontario, Canada L8S 4P4. robertsauladam@yahoo.ca
authors.forename: Robert S
authors.initials: RS
authors.lastname: Adam
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Kertes
authors.forename: Wai-Ching
authors.initials: WC
authors.lastname: Lam
mesh_terms: D002648:Child; D002675:Child, Preschool; D003452:Cryosurgery; D005122:Exudates and Transudates; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D017075:Laser Coagulation; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009887:Ophthalmoscopy; D012163:Retinal Detachment / Q000503:physiopathology / Q000601:surgery*; D012171:Retinal Vessels / Q000601:surgery*; D012189:Retrospective Studies; D013684:Telangiectasis / Q000503:physiopathology / Q000601:surgery*; D014792:Visual Acuity