[Study on the myoelectric activity of dilatation muscles of upper airway in patients with obstructive sleep apnea-hypopnea syndrome under asleep condition].
OBJECTIVE
To observe the changes of the electromyography(EMG) of the dilatation muscles of upper airway in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) under asleep condition and to explore their functions and significance.


METHODS
The myoelectronic activity of levator palatini muscle, tensor palatini muscle, genioglossus muscle was measured by ENG in patients with moderate to serious OSAHS before and after induction of sleep and was compared with normal control.


RESULTS
(1) The myoelectronic activity of dilation muscles of the upper airway in OSAHS patients were higher than that in control under awake condition (P < 0.01). (2) When the patients were asleep, the myoelectronic activity of these muscles dropped significantly (P < 0.01). (3) The decrease of myoelectronic activity of dilatation muscles of upper airway was more dramatic in patients with OSAHS than that in control when turned from awake condition to asleep condition (P < 0.01).


CONCLUSIONS
The compensative raise of myoelectronic activity of dilatation muscles of upper airway under awake condition and the decompensation when asleep in patients with OSAHS were important in the pathogenesis.
Ji
Junfeng
J
Department of Otolaryngology-Head and Neck Surgery, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China.
Zhou
Mei
M
Jiang
Manjie
M
Xue
Fei
F
Wang
Qiuping
Q
D000328:Adult; D000368:Aged; D000403:Airway Resistance; D045422:Continuous Positive Airway Pressure; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology*; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology*; D012894:Sleep Stages