title: Sarcomatoid renal cell carcinoma in a young adult.
abstract: Sarcomatoid renal cell carcinoma (SRCC) is an uncommon, aggressive renal cell carcinoma (RCC) accounting for 1.2% to 12.3% of renal cell carcinomas. SRCC may arise from any RCC subtype as it probably results from the de-differentiation of any renal epithelial malignancy. SRCC is characterised by a rapid progression and high metastatic rate. Currently there is no specific effective treatment for it. We report a new case of a 32-year-old man presented with two months backache. Ultrasound revealed a 7.5 cm heterogeneous mass at the inferior pole of the left kidney. A nephrectomy was performed. Histological study diagnosed a sarcomatoid renal cell carcinoma. The patient was doing well 6 months after initial surgery and then was lost to follow-up.
authors.affiliation: Service d'Anatomie et de Cytologie Pathologiques, Hôpital "Charles Nicolle", Tunis, Tunisie. nadia.kourda@rns.tn
authors.forename: N
authors.initials: N
authors.lastname: Kourda
authors.forename: A
authors.initials: A
authors.lastname: Zeddini
authors.forename: M R
authors.initials: MR
authors.lastname: Zaafrani
authors.forename: R
authors.initials: R
authors.lastname: Zermani
authors.forename: L
authors.initials: L
authors.lastname: Ferchichi
authors.forename: M
authors.initials: M
authors.lastname: Ayed
authors.forename: S Baltagi-Ben
authors.initials: SB
authors.lastname: Jilani
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis*; D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000473:pathology*; D049109:Cell Proliferation; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology*; D008297:Male; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D014746:Vimentin; D007633:Keratins