title: Cherubism: long-term follow-up of 2 patients in whom it regressed without treatment.
abstract: Cherubism is a rare hereditary, self-limiting fibrous dysplasia characterised by painless enlargement of the jaws in childhood. Although, it is accepted that the lesions of cherubism are eventually replaced by bone, there have been few long-term follow-up reports with clinicoradiographic documentation of spontaneous remission of the disease, without treatment. We report two cases of cherubic boys who were followed for 17 and 19 years. Clinicoradiographic examination during this period showed regression of the disease without surgical correction.
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. guilhermeccs@ufmg.br
authors.forename: Guilherme Costa Carvalho
authors.initials: GC
authors.lastname: Silva
authors.forename: Ricardo Santiago
authors.initials: RS
authors.lastname: Gomez
authors.forename: Tainah Couto
authors.initials: TC
authors.lastname: Vieira
authors.forename: Edgard Carvalho
authors.initials: EC
authors.lastname: Silva
mesh_terms: D002636:Cherubism / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011859:Radiography; D012075:Remission, Spontaneous