title: Increased risk of chronic suppurative lung disease after measles or pertussis in non-vaccinated children.
abstract: We retrospectively analysed 23 children originating from Campania--Southern Italy--with recurrent pneumonia and chest high-resolution computed tomography (HRCT) proven bronchiectasis. In six patients (26%) who had not undergone measles or pertussis vaccination, recurrent pneumonia started after an episode of lower respiratory tract infection complicating pertussis (n=2) or measles (n=4), contracted at a mean age of 3.6 years. Thirty-three percent (2/6) and 67% (4/6) of the patients had bilateral or monolobar disease, respectively, while in two subjects (33%) bronchiectasis were found in all lobes. These findings indicate an increased risk of developing bronchiectasis after measles or pertussis.
authors.forename: Silvia
authors.initials: S
authors.lastname: Montella
authors.forename: Sara
authors.initials: S
authors.lastname: De Stefano
authors.forename: Francesco
authors.initials: F
authors.lastname: Sperlì
authors.forename: Federico
authors.initials: F
authors.lastname: Barbarano
authors.forename: Francesca
authors.initials: F
authors.lastname: Santamaria
mesh_terms: D001987:Bronchiectasis / Q000453:epidemiology / Q000209:etiology; D002648:Child; D002908:Chronic Disease; D004196:Disease Outbreaks; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008171:Lung Diseases / Q000453:epidemiology / Q000209:etiology*; D008457:Measles / Q000150:complications* / Q000453:epidemiology; D011014:Pneumonia / Q000453:epidemiology / Q000209:etiology; D012306:Risk; D014611:Vaccination; D014917:Whooping Cough / Q000150:complications* / Q000453:epidemiology