title: [Necrobiosis lipoidica - 3 case reports].
abstract: Necrobiosis lipoidica is a rare degenerative disease mostly seen on the legs. The association to diabetes mellitus is usual. We report three patients with necrobiosis lipoidica located on the extremities, 2 of them were already treated for diabetes. Necrobiosis lipoidica has distinctive clinical and histological appearances. The lesions appear as well circumscribed, erythematous plaques, with a depressed centre. Some of these lesions may progress to ulcers. The legs are commonly involved. Angiopathy leading to thrombosis of the cutaneous vessels has been implicated in its pathogeny. There is no specific therapy for this disease Topical and/or intralesional corticosteroids are the most widely used treatment.
authors.affiliation: Service de Dermatologie, CHU H. Chaker, Sfax, Tunisie. madiha.mseddi@laposte.net
authors.forename: M
authors.initials: M
authors.lastname: Mseddi
authors.forename: S
authors.initials: S
authors.lastname: Marrekchi
authors.forename: S
authors.initials: S
authors.lastname: Bouassida
authors.forename: Th
authors.initials: T
authors.lastname: Meziou
authors.forename: S
authors.initials: S
authors.lastname: Boudaya
authors.forename: H
authors.initials: H
authors.lastname: Turki
authors.forename: A
authors.initials: A
authors.lastname: Zahaf
mesh_terms: D000293:Adolescent; D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications* / Q000473:pathology*