Enecarbamates as imine surrogates: nucleophilic addition of 1,3-dicarbonyl compounds to enecarbamates.
[reaction: see text] Novel Mannich-type reactions of 1,3-dicarbonyl compounds with enecarbamates have been developed. Stable and storable enecarbamates work as surrogates of aliphatic aldehyde-derived imines, which are known to be difficult to isolate and store.
Kobayashi
Shu
S
Graduate School of Pharmaceutical Sciences, The University of Tokyo, The HFRE Division, ERATO, Japan Science and Technology Agency (JST), Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. skobayas@mol.f.u-tokyo.ac.jp
Gustafsson
Tomas
T
Shimizu
Yusuke
Y
Kiyohara
Hiroshi
H
Matsubara
Ryosuke
R