title: [Merkel cell carcinoma].
abstract: Merkel cell carcinoma (Mcc) is a very rare, malignant, neuroendocrine tumour. Mcc has an aggressive behavior, local recurrence, and regional or distant metastasis generally develop within a short period of time. At the Oral Medicine Department 158,056 patients were treated between 1970 and 2004. A single case of Mcc was diagnosed, in a 79-year-old woman. The tumour was localized to the upper lip. After successful cryosurgery and a 7-year tumour-free period, a new tumour developed in her palatine tonsil. It was an anaplastic carcinoma with neuroendocrine features, raising the possibility of a late haematogenous metastasis, a second field tumour, or a second primary tumour. The clinical, histological, immunohistochemical and genetic findings suggested that the tumour of the palatine tonsil is a second field tumour.
authors.affiliation: Szegedi Tudományegyetem, Altalános Orvostudományi Kar, Fogászati és Szájsebészeti Klinika.
authors.forename: Judit
authors.initials: J
authors.lastname: Nagy
authors.forename: Béla
authors.initials: B
authors.lastname: Iványi
authors.forename: István
authors.initials: I
authors.lastname: Sonkodi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D003452:Cryosurgery; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008046:Lip; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D014067:Tonsillar Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery