[Diagnosis and therapy of auditory synaptopathy/neuropathy].
Pathological auditory brainstem responses (lack of responses, elevated thresholds and perturbed waveforms) in combination with present otoacoustic emissions are typical audiometric findings in patients with a hearing impairment that particularly affects speech comprehension or complete deafness. This heterogenous group of disorders first described as "auditory neuropathy" includes dysfunction of peripheral synaptic coding of sound by inner hair cells (synaptopathy) and/or of the generation and propagation of action potentials in the auditory nerve (neuropathy). This joint statement provides prevailing background information as well as recommendations on diagnosis and treatment. The statement focuses on the handling in the german language area but also refers to current international statements.
Moser
T
T
HNO-Universitätsklinik Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen. tmoser@gwdg.de
Strenzke
N
N
Meyer
A
A
Lesinski-Schiedat
A
A
Lenarz
T
T
Beutner
D
D
Foerst
A
A
Lang-Roth
R
R
von Wedel
H
H
Walger
M
M
Gross
M
M
Keilmann
A
A
Limberger
A
A
Steffens
T
T
Strutz
J
J
D001933:Brain Stem / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003056:Cochlear Nerve / Q000503:physiopathology; D003638:Deafness / Q000175:diagnosis / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D006199:Hair Cells, Auditory, Inner / Q000503:physiopathology; D006310:Hearing Aids; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000503:physiopathology / Q000534:rehabilitation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D013067:Speech Perception / Q000502:physiology; D013069:Speech Reception Threshold Test; D013136:Spiral Ganglion / Q000503:physiopathology; D013569:Synapses; D000160:Vestibulocochlear Nerve Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000534:rehabilitation