title: [Lobular idiopathic granulomatos mastitis. About 10 cases].
abstract: Our retrospective study was performed on 10 cases of granulomatous mastitis registered in Obstetric Gynaecology Department and Pathology Department of CHU F. Hached, Sousse, during 8 years period. The mean age was 36.4 years (range 32-59). Among these 10 cases. 8 were observed in reproductive-age women and 2 were noted in menopausal women. Clinical findings showed unilateral breast nodule associated with inflammatory signs in 4 cases, mammelonary retraction in 2 cases and serous or sero-purulent mamelonnary flow in 4 cases. Mamnmographic examination suggested a malignant tumor in 5 patients. In all cases, the diagnosis is made by histopathology. Surgical treatment consisted in wide excision with drainage or radical mastectomy, eventually with combination with antibiotic therapy and non steroid anti-inflammatory drugs. Prognostic features showed a good cicatrization in 4 cases, local recurrence and cutaneous fistulization in one patient. Granulomatous mastitis aetiology is still unclear, auto-immune aetio-pathogenesis appears more interesting and should be clarified.
authors.affiliation: Laboratoire d'anatomie et de cytologie pathologiques, CHU Faizet Hached, Sousse, Tunisie.
authors.forename: Sihem
authors.initials: S
authors.lastname: Hmissa
authors.forename: Wassila
authors.initials: W
authors.lastname: Sahraoui
authors.forename: Nabiha
authors.initials: N
authors.lastname: Missaoui
authors.forename: Wided
authors.initials: W
authors.lastname: Stita
authors.forename: Moncef
authors.initials: M
authors.lastname: Mokni
authors.forename: Mohamed T
authors.initials: MT
authors.lastname: Yacoubi
authors.forename: Hedi
authors.initials: H
authors.lastname: Khairi
authors.forename: Sadok
authors.initials: S
authors.lastname: Korbi
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001940:Breast / Q000473:pathology; D003937:Diagnosis, Differential; D004322:Drainage; D005260:Female; D006801:Humans; D008327:Mammography; D015409:Mastectomy, Radical; D008413:Mastitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal