[Chronic inflammation increases the risk of cardiovascular disease in patients with rheumatoid arthritis].
Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality due to atherosclerosis. This cannot be explained by an increased presence of traditional risk factors but seems to depend on inflammatory mechanisms. The association of inflammatory pathways with atherosclerosis is complex, and more research is required to optimise preventative measures against cardiovascular complications in inflammatory rheumatic diseases.
Troelsen
Lone N
LN
H:S Rigshospitalet, Finsencentret, Reumatologisk Klinik 4242, København Ø. lone.troelsen@mail.dk
Jacobsen
Søren
S
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D050197:Atherosclerosis / Q000150:complications / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D016207:Cytokines / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D018836:Inflammation Mediators / Q000276:immunology; D012307:Risk Factors
D000893:Anti-Inflammatory Agents; D000924:Anticholesteremic Agents; D016207:Cytokines; D007166:Immunosuppressive Agents; D018836:Inflammation Mediators