title: Etanercept therapy for silicone granuloma.
abstract: A patient developed a typical, painful, and debilitating reaction on the thighs following injection of ostensibly medical grade "silicone" to achieve alteration of body contours. The refractory silicone granuloma responded dramatically to treatment with etanercept.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Anupam M
authors.initials: AM
authors.lastname: Desai
authors.forename: John
authors.initials: J
authors.lastname: Browning
authors.forename: Theodore
authors.initials: T
authors.lastname: Rosen
mesh_terms: D003357:Cosmetic Techniques / Q000009:adverse effects*; D003937:Diagnosis, Differential; D000068800:Etanercept; D015745:Granuloma, Foreign-Body / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use*; D020034:Silicone Gels / Q000008:administration & dosage / Q000009:adverse effects*; D013848:Thigh / Q000473:pathology; D014189:Transsexualism; D014409:Tumor Necrosis Factor-alpha
chemical_list: D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins; D020034:Silicone Gels; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept