[Non-corticosteroid drug-induced metabolic bone disease].
After osteoporotic fracture or low bone mineral density measurements, it is necessary to look for secondary causes of osteoporosis, such as drugs. Corticosteroids are the most common cause of drug-induced metabolic bone disease. Other drugs responsible for bone disease include: aromatase inhibitors, GnRH agonists, anticonvulsants, heparin, and L thyroxin at TSH-suppressive doses. Confirmation is required of data about neuroleptics and antivitamin K.
Briot
Karine
K
Service de rhumatologie, Université René Descartes Paris V, Hôpital Cochin, Paris (75). karine.briot@cch.aphp.fr
D000368:Aged; D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D047072:Aromatase Inhibitors / Q000009:adverse effects; D015519:Bone Density; D002648:Child; D003524:Cyclosporins / Q000009:adverse effects; D003720:Densitometry; D018450:Disease Progression; D004232:Diuretics / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D050723:Fractures, Bone / Q000209:etiology; D007987:Gonadotropin-Releasing Hormone / Q000187:drug effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007049:Iatrogenic Disease; D007166:Immunosuppressive Agents / Q000009:adverse effects; D018020:Lithium Compounds / Q000009:adverse effects; D008297:Male; D008593:Menopause; D008727:Methotrexate / Q000009:adverse effects; D008875:Middle Aged; D010018:Osteomalacia / Q000139:chemically induced* / Q000150:complications; D010024:Osteoporosis / Q000139:chemically induced* / Q000150:complications; D015663:Osteoporosis, Postmenopausal / Q000139:chemically induced / Q000150:complications; D010919:Placebos; D011446:Prospective Studies; D011480:Protease Inhibitors / Q000009:adverse effects; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D016559:Tacrolimus / Q000009:adverse effects; D013963:Thyroid Hormones / Q000009:adverse effects; D013997:Time Factors
D000925:Anticoagulants; D000927:Anticonvulsants; D014150:Antipsychotic Agents; D047072:Aromatase Inhibitors; D003524:Cyclosporins; D004232:Diuretics; D007004:Hypoglycemic Agents; D007166:Immunosuppressive Agents; D018020:Lithium Compounds; D010919:Placebos; D011480:Protease Inhibitors; D013963:Thyroid Hormones; D007987:Gonadotropin-Releasing Hormone; D016559:Tacrolimus; D008727:Methotrexate