title: Venous gas embolism following hydrogen peroxide irrigation during debridement of chronic osteomyelitis lesion.
abstract: We report a case of a previously healthy 53-year-old man who developed an intra-operative catastrophic event occurring in association with the use of hydrogen peroxide for wound irrigation following surgical debridement of a chronic osteomyelitis lesion of the humerus. It is our intention to highlight this potentially fatal consequence of hydrogen peroxide irrigation as part of bone debridement procedure. This case will serve as a reminder to orthopaedic surgeons who frequently use hydrogen peroxide in their surgical practice.
authors.affiliation: Department of Orthopaedics, Traumatology & Rehabilitation, Kulliyyah of Medicine, International Islamic University of Malaysia, Kuantan, Pahang, Malaysia.
authors.forename: A
authors.initials: A
authors.lastname: Shukrimi
authors.forename: C A
authors.initials: CA
authors.lastname: Aminudin
authors.forename: M A
authors.initials: MA
authors.lastname: Azril
authors.forename: M R A
authors.initials: MR
authors.lastname: Hadi
mesh_terms: D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D001132:Arm / Q000473:pathology; D002908:Chronic Disease; D003646:Debridement / Q000009:adverse effects*; D004618:Embolism, Air / Q000139:chemically induced*; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000009:adverse effects*; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000601:surgery*; D007507:Therapeutic Irrigation / Q000009:adverse effects*
chemical_list: D000891:Anti-Infective Agents, Local; D006861:Hydrogen Peroxide