Enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B.
An enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B was accomplished in line with our previously reported synthetic pathway for their (1R,5S)-enantiomer. The use of "EtSCeCl2" prepared from EtSLi and CeCl3, instead of previously employed EtSLi itself, for the formation of thiol ester intermediates prevented any undesirable epimerization occurring in the process.
Morita
Akira
A
Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Japan.
Kiyota
Hiromasa
H
Kuwahara
Shigefumi
S
D019380:Anti-HIV Agents / Q000138:chemical synthesis; D007202:Indicators and Reagents; D012717:Sesquiterpenes / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013463:Sulfuric Acid Esters
D019380:Anti-HIV Agents; D007202:Indicators and Reagents; D012717:Sesquiterpenes; D013463:Sulfuric Acid Esters; C516004:litseaverticillol A; C498385:litseaverticillol B