title: 2-year Clinical evaluation of sodium hypochlorite treatment in the restoration of non-carious cervical lesions: a pilot study.
abstract: This pilot study evaluated the effect of removing acid-etch-exposed dentin collagen on the clinical performance of composite restorations of noncarious cervical lesions placed using 2 different adhesive systems. Fifty-six restorations were placed in 14 subjects, each subject receiving at least 4 restorations. No cavity preparation or mechanical retention form was used. The variables tested were: 1) dentin treatment prior to application of the adhesive (acid-etch only vs acid-etch and collagen removal) and 2) type of adhesive (acetone- vs ethanol-based). For the acid-etch only groups, enamel and dentin were etched with 37% phosphoric acid for 15 seconds, rinsed and blot dried. Prime & Bond 2.1 (Dentsply Caulk) or Single Bond (3M ESPE) was applied and light-cured according to the manufacturer's instructions. For the acid-etch and collagen removal groups, the enamel and dentin were etched and rinsed in the same manner and a 10% sodium hypochlorite (NaOCl) solution was applied for 60 seconds and rinsed before adhesive application. Filtek Z-250 (3M ESPE) was applied to all specimens and light-cured according to the manufacturer's instructions, and the restorations were finished and polished immediately. The restorations were evaluated for pre- and post-operative sensitivity, retention, marginal staining and secondary caries at baseline, 12 and 24 months after placement, using modified USPHS criteria. Data were analyzed using the Kruskal-Wallis and Wilcoxon statistical tests (p=0.05). At 24 months, the retention rates for Prime & Bond 2.1 with and without NaOCl pretreatment were 80% and 63%, respectively. The corresponding retention rates for Single Bond were 70% and 90%. Marginal staining was minimal. Statistical analyses revealed no significant differences at any time interval between groups for retention or marginal staining. No post-operative sensitivity or secondary caries was detected during the study.
authors.affiliation: School of Pharmacy, Dentistry and Nursing, Federal University of Ceard, Fortaleza, Brazil.
authors.forename: Vicente de Paulo Aragão
authors.initials: Vde P
authors.lastname: Saboia
authors.forename: Paulo César
authors.initials: PC
authors.lastname: Almeida
authors.forename: André V
authors.initials: AV
authors.lastname: Rittet
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Swift
authors.forename: Luiz André Freire
authors.initials: LA
authors.lastname: Pimenta
mesh_terms: D000096:Acetone / Q000737:chemistry; D000134:Acid Etching, Dental; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D003094:Collagen / Q000187:drug effects; D003116:Color; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding; D003743:Dental Enamel / Q000187:drug effects; D003793:Dental Restoration, Permanent / Q000379:methods*; D003804:Dentin / Q000187:drug effects; D017220:Dentin-Bonding Agents / Q000737:chemistry; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D016877:Oxidants / Q000627:therapeutic use*; D010756:Phosphoric Acids / Q000737:chemistry; D010865:Pilot Projects; D011109:Polymethacrylic Acids / Q000737:chemistry; D012973:Sodium Hypochlorite / Q000627:therapeutic use*; D013499:Surface Properties; D019237:Tooth Cervix / Q000187:drug effects*; D014076:Tooth Diseases / Q000628:therapy*
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; C444701:Filtek Z250; D016877:Oxidants; D010756:Phosphoric Acids; D011109:Polymethacrylic Acids; C444444:prime and bond 2.1; C115612:single bond; D000096:Acetone; D017438:Bisphenol A-Glycidyl Methacrylate; D003094:Collagen; D012973:Sodium Hypochlorite; C030242:phosphoric acid