New nematicidal azaphilones from the aquatic fungus Pseudohalonectria adversaria YMF1.01019.
Two new azaphilone metabolites, named pseudohalonectrin A (1) and B (2), were isolated from the culture of the aquatic fungus Pseudohalonectria adversaria YMF1.01019, originally separated from submerged wood in Yunnan Province, China. Pseudohalonectrin A and B were assessed for their nematicidal activity against the pine wood nematode Bursaphelenchus xylophilus and their structures were defined after spectral analysis. This is the first report of secondary metabolites from any member of the genus Pseudohalonectria.
Dong
Jinyan
J
Key Laboratory for Conservation and Utilization of Bioresources, Yunnan University, Kunming, Yunnan, People's Republic of China.
Zhou
Yongping
Y
Li
Ru
R
Zhou
Wei
W
Li
Lei
L
Zhu
Yanhui
Y
Huang
Rong
R
Zhang
Keqin
K
D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D001578:Benzopyrans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008968:Molecular Conformation; D017187:Tylenchida / Q000187:drug effects
D000969:Antinematodal Agents; D001578:Benzopyrans; C515722:pseudohalonectrin A; C515723:pseudohalonectrin B