Highly enantioselective transfer hydrogenation of alpha,beta-unsaturated ketones.
We describe an efficient and highly enantioselective conjugate transfer hydrogenation of alpha,beta-unsaturated ketones that is catalyzed by a salt made from tert-butyl valinate and a recently introduced powerful chiral phosphoric acid catalyst (TRIP).
Martin
Nolwenn J A
NJ
Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim an der Ruhr, Germany.
List
Benjamin
B