Canine ovarian serous papillary adenocarcinoma with neoplastic hypercalcemia.
A female golden retriever was referred to assess a history of a palpable abdominal mass. A serum chemistry analysis revealed elevated concentrations of blood urea nitrogen, creatinine, calcium, and parathyroid hormone-related protein (PTH-rP). Exploratory laparotomy revealed an ovoid mass within the right ovary. This mass was removed surgically by performing an ovariohysterectomy. The right ovarian mass was diagnosed as a serous papillary adenocarcinoma. Following surgery, the dog recovered, and the serum calcium and PTH-rP concentrations decreased. Therefore, concentrations of PTH-rP and calcium might be associated with serous papillary adenocarcinomas. Serial evaluation of the serum PTH-rP and calcium was useful for evaluating the prognosis.
Hori
Yasutomo
Y
Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan.
Uechi
Masami
M
Kanakubo
Kayo
K
Sano
Tadashi
T
Oyamada
Toshifumi
T
D000231:Adenocarcinoma, Papillary / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000209:etiology*; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*