New approach to the total synthesis of (-)-zeylenone from shikimic acid.
The natural antitumor product (-)-zeylenone was prepared for the first time in a stereoselective synthesis from shikimic acid.
Zhang
Yi
Y
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu
An
A
Ye
Zu Guang
ZG
Lin
Jia
J
Xu
Li Zhen
LZ
Yang
Shi Lin
SL
D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000737:chemistry; D004146:Dioxanes / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D012765:Shikimic Acid / Q000737:chemistry*; D013237:Stereoisomerism
D003510:Cyclohexanes; D004146:Dioxanes; C516240:zeylenone; D012765:Shikimic Acid