[Normalisation of contralateral adrenal function after long-term mitotane therapy in a girl after surgical treatment of adrenocortical carcinoma].
The main method of treatment of adrenocortical tumours is surgery. The efficacy of the mitotane therapy is still controversial with many serious side effects of the therapy. Moreover, patients receiving mitotane should be carefully monitored for adrenal insufficiency and usually require long-term hormone replacement therapy. We present a rare case of normalisation of the contralateral adrenal function after long-term mitotane therapy as a post-surgical treatment of the adrenocortical tumour.
Lecka
Agnieszka
A
Klinika Pediatrii, Oddział Endokrynologii Instytutu "Pomnik--Centrum Zdrowia Dziecka" w Warszawie, Warszawa. alecka@amwaw.edu.pl
Ginalska-Malinowska
Maria
M
D000306:Adrenal Cortex Neoplasms / Q000188:drug therapy* / Q000601:surgery; D000311:Adrenal Glands / Q000503:physiopathology*; D018268:Adrenocortical Carcinoma / Q000188:drug therapy* / Q000601:surgery; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008939:Mitotane / Q000627:therapeutic use*; D020127:Recovery of Function; D013256:Steroids; D016896:Treatment Outcome
D018931:Antineoplastic Agents, Hormonal; D013256:Steroids; D008939:Mitotane; D006854:Hydrocortisone