New drugs for neuraxial blockade.
Recent years have seen a dramatic increase in the number of agents used for neuraxial blockade. Together with the developments in local anaesthetics and opioids, completely new categories of agents have been investigated for intrathecal and epidural use. A review of the recent literature reveals the potential for improvement in achieving balanced anaesthesia and analgesia, in particular combining agents to reduce adverse effects.
Schug
S A
SA
Section of Anaesthetics, Department of Pharmacology, University of Auckland, Auckland, New Zealand. s.schug@auckland.ac.nz
Buerkle
H
H
Moharib
M
M
Cardwell
H M
HM