title: [Small cell carcinoma of the prostate: a case report].
abstract: A 79-year-old man was admitted to our department with a chief complaint of urinary incontinence. The prostate was enlarged (145 cc), although the serum level of prostate specific antigen (PSA) was within the normal range (1.09 ng/ml). Digital rectal examination showed an enlarged, irregular prostate with stony hardness. We performed a prostate biopsy and histological examinations indicated poorly differentiated adenocarcinoma with a Gleason score of 5+5=10. A computed tomographic (CT) scan revealed a prostatic tumor invading the bladder, seminal vesicle and rectum. He was diagnosed with a stage T4N1M0 adenocarcinoma of the prostate. He was started-on hormonal therapy, but died one month from the start of treatment. Histological and immunohistological examinations were repeated; suggesting small cell neuroendocrine carcinoma of the prostate.
authors.affiliation: The Department of Urology, Yamagata Prefectural Central Hospital.
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Sasaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Kunio
authors.initials: K
authors.lastname: Ono
authors.forename: Osamu
authors.initials: O
authors.lastname: Sugano
authors.forename: Syunichi
authors.initials: S
authors.lastname: Sasao
authors.forename: Senji
authors.initials: S
authors.lastname: Hoshi
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D051517:Digital Rectal Examination; D006801:Humans; D008297:Male; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen