Characterization of different samples of quercetin in solid-state: indication of polymorphism occurrence.
The present work was designed to compare four commercial samples of quercetin, three of them presenting pharmaceutical grade (QPGa, QPGb and QPGc) and the other one pro-analysi grade (QPA) by means of different techniques. Physical and chromatographic characterization of these samples shows different properties following its origin, especially a clear evidence of polymorphism occurrence.
Borghetti
G S
GS
Programa de Pós-Graduação em Ciências Farmacêuticas, Departamento de Controle e Produção de Medicamentos, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Allegre, Brasil.
Costa
I M
IM
Petrovick
P R
PR
Pereira
V P
VP
Bassani
V L
VL
D002853:Chromatography, Liquid; D018360:Crystallography, X-Ray; D007536:Isomerism; D008855:Microscopy, Electron, Scanning; D011794:Quercetin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000737:chemistry; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D011794:Quercetin