Deep morphea after vaccination in two young children.
A number of dermatoses have been reported to appear in close temporal or spatial relationship to the intramuscular injection of vaccines. We describe two young children who had morphea consistent with the deep morphea type (morphea profunda) that appeared at the site of a previous vaccination. Trauma has been implicated as an important trigger of morphea, both in children and in adults. Furthermore, vaccines might induce an immune response, which could lead to morphea in predisposed individuals.
Torrelo
Antonio
A
Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain. atorrelo@aedv.es
Suárez
José
J
Colmenero
Isabel
I
Azorín
Daniel
D
Perera
Antonio
A
Zambrano
Antonio
A
D002675:Child, Preschool; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular / Q000009:adverse effects*; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage* / Q000009:adverse effects; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology; D014611:Vaccination / Q000009:adverse effects*
D015721:Diphtheria-Tetanus-Pertussis Vaccine; D022542:Measles-Mumps-Rubella Vaccine