SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry.
Huang
I-Chueh
IC
Harvard Medical School, Boston, Massachusetts 02115, USA.
Bosch
Berend Jan
BJ
Li
Wenhui
W
Farzan
Michael
M
Rottier
Peter M
PM
Choe
Hyeryun
H
D000085962:Angiotensin-Converting Enzyme 2; D056668:Cathepsin L; D002403:Cathepsins / Q000737:chemistry / Q000502:physiology*; D002460:Cell Line; D017934:Coronavirus / Q000472:pathogenicity*; D003546:Cysteine Endopeptidases / Q000737:chemistry; D006801:Humans; D008561:Membrane Fusion; D008562:Membrane Glycoproteins / Q000502:physiology*; D007703:Peptidyl-Dipeptidase A / Q000502:physiology; D045473:Severe acute respiratory syndrome-related coronavirus / Q000472:pathogenicity*; D064370:Spike Glycoprotein, Coronavirus; D014759:Viral Envelope Proteins / Q000737:chemistry / Q000502:physiology*
D008562:Membrane Glycoproteins; D064370:Spike Glycoprotein, Coronavirus; D014759:Viral Envelope Proteins; D002403:Cathepsins; D007703:Peptidyl-Dipeptidase A; C000705307:ACE2 protein, human; D000085962:Angiotensin-Converting Enzyme 2; D003546:Cysteine Endopeptidases; C534281:CTSL protein, human; D056668:Cathepsin L