Possible magnetic multifunctional nanoplatforms in medicine.
Recently, magnetic nanoparticles have attracted attention because of their potential in biomedicine. They can be applied to special medical techniques, such as separation, immunoassay, magnetic resonance imaging (MRI), drug delivery, and hyperthermia, and so on. But these nanoparticles only have one or two kinds of functions and cannot realize multipurpose. Therefore, we propose that it is need to constitute magnetic multifunctional nanoplatforms, which not only have delivery property of gene vector and drug carrier, but also have heating property of thermseeds in the alternative magnetic field. Recent trials have proved that gene therapy combined with chemotherapy and hyperthermia achieves better results than single therapy strategy. But this is difficult in clinical practice. With the development of the magnetic multifunctional nanoplatforms, the combined treatment is feasible in clinical practice. This nanoplatforms is versatile, and can be applied to wide fields. The use of magnetic multifunctional nanoplatforms will further improve medical techniques.
Xiao
XuXian
X
School of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, PR China. xxxiaocsu@yahoo.com.cn
He
QiongQiong
Q
Huang
KeLong
K
D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008280:Magnetics; D053758:Nanoparticles