24-hour heart rate variability in patients with gastroesophageal reflux disease.
The GERD pathogenesis may be associated with disturbances of the autonomic nervous system (ANS), which can be revealed using heart rate variability studies (HRV). The aim of presented study was to estimate the circadian ANS activity in 24-hour HRV recordings in GERD patients, both in non-erosive form (NERD), and with erosive, inflammatory changes in the esophagus (ERD patients). Our results demonstrated disturbances in the parasympathetic ANS part, but they also delivered the proofs for possible sympathetic disorder. That is why the autonomic neuropathy in GERD patients may have mixed character.
Dobrek
Lukasz
L
Katedra Patofizjologii, Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
Nowakowski
Michał
M
Syguła
Anna
A
Lipczyński
Artur
A
Barylak
Halina
H
Herman
Roman Maria
RM
Thor
Piotr Jan
PJ
D000328:Adult; D000704:Analysis of Variance; D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D001341:Autonomic Nervous System / Q000503:physiopathology; D001342:Autonomic Nervous System Diseases / Q000150:complications; D002940:Circadian Rhythm; D015716:Electrocardiography, Ambulatory; D050782:Esophageal pH Monitoring; D005260:Female; D005764:Gastroesophageal Reflux / Q000145:classification / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged