[A comparative study of the inducing effect of homoserine lactone and hexylresorcinol on phenotypic dissociation in bacteria].
It has been shown that the phenotypic dissociation of Bacillus subtilis SK1 and S. typhimurium TA100 is induced by hexylresorcinol, an exogenous non-species-specific autoregulator of pleiotropic action, which is genotoxic for both pro- and eukaryotes. Nongenotoxic homoserine lactone, a chemical analogue of cell-density-responsive species-specific regulators, does not induce bacterial dissociation. The phage resistance of the S- and R-type variants of S. typhimurium TA100 induced by hexylresorcinol has been found to be the same as that of the S- and R-type salmonella variants obtained by the routine subculturing method.
Margulis
A B
AB
Kolpakov
A I
AI
Il'inskaia
O N
ON
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D006604:Hexylresorcinol / Q000494:pharmacology*; D010641:Phenotype; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development
D003470:Culture Media; C088386:homoserine lactone; D015107:4-Butyrolactone; D006604:Hexylresorcinol