Cholesterol gallstones.
Cholesterol cholelithiasis is common in Western populations and represents a consequence of altered cholesterol homeostasis. Gallstones form because of a complex and incompletely understood series of metabolic and physicochemical events that promote cholesterol crystallization in bile. In the context of current paradigms, this article reviews recent progress in research on biliary lipid metabolism and the pathogenesis of cholesterol gallstones.
Hyogo
Hideyuki
H
Department of Medicine, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Tazuma
Susumu
S
Cohen
David E
DE