Pediatric neurosurgery.
Randomized controlled trials of neurosurgical procedures involving children have been organized infrequently; as a consequence, the majority of pediatric neurosurgical practice is not supported by class I data. Furthermore, many trials that have been reported suffer from serious methodological shortcomings such as insufficient power and poor statistical analysis. Finally, several trials of neurosurgical techniques that are frequently performed on children have either excluded children from participation or include an insufficient number of children to draw strong conclusions. Despite these shortcomings, pediatric neurosurgery, like all fields in medicine, is gradually moving towards a more stringent evidence-based medicine standard. This chapter will attempt to summarize the recent progress that has been made in this area.
Maher
Cormac O
CO
Department of Neurosurgery, Children's Hospital Boston, Boston, Mass.,USA.
Cohen-Gadol
Aaron A
AA
Raffel
Corey
C
D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D019635:Neurosurgical Procedures; D010372:Pediatrics