title: Impact of blood salvage during liver transplantation on reduction in transfusion requirements.
abstract: OBJECTIVE
  The aim of this study was to analyse the changes in transfusion requirements, in patients submitted to orthotopic liver transplantation from cadaveric donors, with the use of intraoperative red blood cell salvage (Cell Saver).
  
  
  METHODS
  Data from 41 transplants were analysed. Intraoperative blood loss was calculated from the cell salvage, suction and the swabs. The autologous and heterologous transfusions were recorded The red blood salvage was performed using the Cell Saver 5 System (Haemonetics). For analysis the patients were divided in two groups: one that used the Cell Saver and another that didn't.
  
  
  RESULTS
  The median age of the patients was 50 years and the main indication for liver transplantation was cirrhosis (35 cases-85.3%). The median blood loss was 8362+3994 ml (with the Cell Saver) and 10824+7002 ml (without the Cell Saver) and the median transfusion of heterologous packed red blood cells was 9.6+8 units (with the Cell Saver) compared to 22.3+21 units (without the Cell Saver).
  
  
  CONCLUSIONS
  The Cells Saver has the potential to reduce the need for heterologous blood transfusion reducing the risks of transmissible diseases.
authors.affiliation: Division of Gastroenterology, Department of Surgery and Anatomy, FMRP, USP, Brazil.
authors.forename: Ajith Kumar
authors.initials: AK
authors.lastname: Sankarankutty
authors.forename: Andreza Correa
authors.initials: AC
authors.lastname: Teixeira
authors.forename: Fernanda Fernandes
authors.initials: FF
authors.lastname: Souza
authors.forename: Enio David
authors.initials: ED
authors.lastname: Mente
authors.forename: Gustavo Ribeiro de
authors.initials: GR
authors.lastname: Oliveira
authors.forename: Rachel Cristina Camargo
authors.initials: RC
authors.lastname: Almeida
authors.forename: Camila Marques de
authors.initials: CM
authors.lastname: Andrade
authors.forename: Eliana Aparecida Lopes
authors.initials: EA
authors.lastname: Origuella
authors.forename: Orlando de Castro e
authors.initials: Ode C
authors.lastname: Silva
mesh_terms: D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006505:Hepatitis / Q000628:therapy; D006801:Humans; D007430:Intraoperative Care; D008104:Liver Cirrhosis, Alcoholic / Q000628:therapy; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians'; D012720:Severity of Illness Index; D065227:Transfusion Reaction; D016896:Treatment Outcome