title: Selective agents for serotonin2C (5-HT2C) receptor.
abstract: The serotonin2C (5-HT2C) receptor has attracted a lot of attention owing to its role in appetite regulation, depression, obsessive-compulsive disorder (OCD), panic disorders, and substance abuse. This review summarizes non-patent and patent literature up to November 2005 that deals with the synthesis and characterization of selective 5-HT2C receptor agonists and antagonists. Highlights on structure-activity relationships have been included, when possible.
authors.affiliation: Università degli Studi di Bari, Dipartimento Farmaco-Chimico, via Orabona, 4, 70125, Bari, Italy.
authors.forename: Enza
authors.initials: E
authors.lastname: Lacivita
authors.forename: Marcello
authors.initials: M
authors.lastname: Leopoldo
mesh_terms: D000818:Animals; D006801:Humans; D015394:Molecular Structure; D058826:Serotonin 5-HT2 Receptor Agonists; D058830:Serotonin 5-HT2 Receptor Antagonists; D012702:Serotonin Antagonists / Q000737:chemistry / Q000494:pharmacology*; D017366:Serotonin Receptor Agonists / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D058826:Serotonin 5-HT2 Receptor Agonists; D058830:Serotonin 5-HT2 Receptor Antagonists; D012702:Serotonin Antagonists; D017366:Serotonin Receptor Agonists