[Psychopharmacological treatment of behavioral and psychological symptoms in dementia].
Behavioural and psychological symptoms of dementia (BPSD) are common and can dominate disease presentation. Antidepressions are commonly prescribed for depressive symptoms, but the evidence to support this practice is weak. The atypical antipsychotics risperidone and olanzepine have significant efficacy for the treatment of aggression and risperidone is also efficacious in the treatment of psychosis, but both with substantially increased risk of stroke. There are no newer studies of benzodiazepines in the treatment of anxiety and in old studies the efficacy are doubtful.
Lolk
Annette
A
Syddansk Universitet, Klinisk Institut, Forskningsenheden for Psykiatri, Psykiatrisk Afdeling P, Odense C. annette.lolk@ouh.fyns-amt.dk
Gulmann
Niels Christian
NC
D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000627:therapeutic use; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000009:adverse effects / Q000627:therapeutic use; D003704:Dementia / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D001523:Mental Disorders / Q000150:complications / Q000188:drug therapy*; D000077152:Olanzapine; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D016896:Treatment Outcome
D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine; D018967:Risperidone; D017367:Selective Serotonin Reuptake Inhibitors