title: Radiology quality assurance in a developing country setting: the 11-valent pneumococcal conjugate vaccine trial, Bohol, Philippines.
abstract: The endpoint used for a phase 3 pneumococcal conjugate vaccine (PCV) trial in Bohol, Philippines was radiographic consolidation. Only one (Bohol Regional Hospital, BRH) of the four surveillance hospitals had a quality control/quality assurance program (QC/QA) prior to the trial. QC/QA was initiated in the three private hospitals. Radiologists from BRH evaluated radiographs from all hospitals based on recommended standards. Four thousand nine hundred and eighty nine films were analyzed. In 2000, the proportion of good quality films was 65% and 29% in BRH and private hospitals, respectively. By 2004, these increased to 92% and 79%, respectively. Poor film quality was commonly due to absence of collimation and poor contrast. The regular QC/QA implementation was necessary to improve film quality and was particularly important in our PCV trial that used X-ray proven consolidation as an endpoint.
authors.affiliation: Bohol Regional Hospital, Tagbilaran City, Bohol, Philippines. ritmari@smartwifi.com.ph
authors.forename: Jose D
authors.initials: JD
authors.lastname: Arcay
authors.forename: Arnaldo F
authors.initials: AF
authors.lastname: Ocampo
authors.forename: Roger K
authors.initials: RK
authors.lastname: Solis
authors.forename: Isnardo B
authors.initials: IB
authors.lastname: Oncog
authors.forename: Alan D
authors.initials: AD
authors.lastname: Diaz
authors.forename: Agnes Corazon C
authors.initials: AC
authors.lastname: Epe
authors.forename: Rummel
authors.initials: R
authors.lastname: Cagadas
authors.forename: Susan
authors.initials: S
authors.lastname: Pabatang
authors.forename: Harald
authors.initials: H
authors.lastname: Ostensen
authors.forename: Marilla G
authors.initials: MG
authors.lastname: Lucero
mesh_terms: D002648:Child; D003906:Developing Countries; D006801:Humans; D010679:Philippines; D022242:Pneumococcal Vaccines / Q000627:therapeutic use*; D011018:Pneumonia, Pneumococcal / Q000000981:diagnostic imaging*; D011785:Quality Assurance, Health Care / Q000379:methods; D011859:Radiography; D011871:Radiology / Q000379:methods / Q000592:standards*
chemical_list: D022242:Pneumococcal Vaccines