Enantioselective nitroaldol (Henry) reaction using copper(II) complexes of (-)-sparteine.
The dichloro[(-)-sparteine-N,N']copper(II) complex provides Henry adducts with high enantioselectivities (73-97% ee) in Henry reaction between nitromethane and various aldehydes.
Maheswaran
H
H
IPC Division, Indian Institute of Chemical Technology, Hyderabad, India. maheswaran_dr@yahoo.com
Prasanth
K Leon
KL
Krishna
G Gopi
GG
Ravikumar
K
K
Sridhar
B
B
Kantam
M Lakshmi
ML
D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008958:Models, Molecular; D009595:Nitroparaffins / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013034:Sparteine / Q000031:analogs & derivatives*; D013237:Stereoisomerism
D001547:Benzaldehydes; D009595:Nitroparaffins; D009942:Organometallic Compounds; D012997:Solvents; D013034:Sparteine; C029915:4-nitrobenzaldehyde; D003300:Copper; D008697:Methane; C008640:nitromethane