title: Costs and benefits of resistance against antimalarial drugs.
abstract: Recent experiments have suggested that resistance to antimalarial drugs, in particular chloroquine, is associated with increased transmission. However, epidemiological patterns suggest the opposite: ie. that resistance should be associated with a transmission cost. Here, Jacob Koella reviews the evidence for either a cost or a benefit of chloroquine resistance and proposes ideas from population and evolutionary biology that might explain the apparent contradiction between experimental and epidemiological evidence.
authors.affiliation: Department of Zoology, University of Aarhus, Universitetsparken B135, DK-8000 Aarhus, Denmark.
authors.forename: J C
authors.initials: JC
authors.lastname: Koella