title: Synthesis of the DEF-bis-spiroacetal of spirastrellolide A exploiting a double asymmetric dihydroxylation/spiroacetalisation strategy.
abstract: An efficient synthesis of the C(26)-C(40) tricyclic [5,6,6]-bis-spiroacetal segment of the marine macrolide spirastrellolide A has been developed, exploiting a novel double Sharpless asymmetric dihydroxylation/spiroacetalisation sequence.
authors.affiliation: University Chemical Laboratory, Lensfield Road, Cambridge, UK CB2 1EW. ip100@cam.ac.uk
authors.forename: Ian
authors.initials: I
authors.lastname: Paterson
authors.forename: Edward A
authors.initials: EA
authors.lastname: Anderson
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Dalby
authors.forename: Jong Ho
authors.initials: JH
authors.lastname: Lim
authors.forename: Philip
authors.initials: P
authors.lastname: Maltas
authors.forename: Christian
authors.initials: C
authors.lastname: Moessner