title: The key to left-right asymmetry.
abstract: Establishment of left-right asymmetry in vertebrates involves cilia as essential components in the breaking of symmetry, an asymmetric signaling cascade, and a midline barrier that helps to maintain asymmetry. A new study suggests that a reaction-diffusion mechanism also plays a key role.
authors.affiliation: Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. tabin@genetics.med.harvard.edu
authors.forename: Clifford J
authors.initials: CJ
authors.lastname: Tabin
mesh_terms: D000818:Animals; D019521:Body Patterning; D002923:Cilia / Q000378:metabolism; D009024:Morphogenesis; D015398:Signal Transduction / Q000502:physiology*