title: [Novel approaches to combination therapy of Hodgkin's disease].
abstract: Data on 668 patients receiving 4-8 cycles of chemotherapy were used to suggest the following approach to complex therapy of Hodgkin's disease: devise a simplified model for Hodgkin's disease, develop a new modality of chemotherapy, demonstrate feasibility of only four chemotherapy cycles in the poor prognosis group, partial response as the ultimate goal of chemotherapy as well as the importance of subtotal dosage under 26-36 Gy sufficient for irradiation of the entire lymphatic collector. Said measures will, in their totality, offer fresh opportunities in treatment of Hodgkin's disease.
authors.forename: V P
authors.initials: VP
authors.lastname: Kharchenko
authors.forename: G A
authors.initials: GA
authors.lastname: Pan'shin
authors.forename: P V
authors.initials: PV
authors.lastname: Datsenko
authors.forename: V M
authors.initials: VM
authors.lastname: Sotnikov
authors.forename: Iu D
authors.initials: IuD
authors.lastname: Mel'nik
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005240:Feasibility Studies; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome