title: [Histoplasma capsulatum with aberrant morphology isolated in Argentina].
abstract: For the first time in Argentina, we describe a strain of Histoplasma capsulatum var. capsulatum with an aberrant morphology that was isolated from a single patient with AIDS. Mycelial phase cultures on agar Sabouraud at 25-28 degrees C showed white, glabrous, umbilicated and centrally radiated colonies. Unusual microscopic findings were the absence of typical conidia, the presence of terminal/intercalary chlamydoconidia with a diameter of 4 pm and of thickened hyphae. Fungal identification was confirmed by the detection of bands H and M species specific antigens in mycelial culture supernatants and reversion to the typical yeast phase on agar brain-heart-cysteine at 37 degrees C. The genomic DNA profile obtained by RAPD-PCR with primers 1281-1283 coincided with the predominant profile of H. capsulatum among isolates from Argentine patients.
authors.affiliation: Departamento Micología, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Vélez Sarsfield 563 1281, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: M F
authors.initials: MF
authors.lastname: Zuiani
authors.forename: M C
authors.initials: MC
authors.lastname: Rivas
authors.forename: W
authors.initials: W
authors.lastname: Lee
authors.forename: L
authors.initials: L
authors.lastname: Guelfand
authors.forename: G
authors.initials: G
authors.lastname: Davel
authors.forename: C E
authors.initials: CE
authors.lastname: Canteros
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D001118:Argentina; D004271:DNA, Fungal / Q000032:analysis; D006658:Histoplasma / Q000166:cytology / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000382:microbiology*; D006801:Humans; D019105:Random Amplified Polymorphic DNA Technique
chemical_list: D004271:DNA, Fungal