The role of pulse pressure in the hemodynamic control of hypertension: exploring the link to cardiovascular remodeling.
OBJECTIVE
To correlate the values in the basic blood pressure groups presented in the JNC 7th with the computed values of the Noninvasive Hemodynamic Analyzer (NHA) and to demonstrate the pathophysiological alterations by three proportional hypertensive models.


METHODS
Hemodynamic values of each of the blood pressure groups presented in the JNC 7th are tabulated for men between 20 and 50 years of age with particular interest in Pulse Pressure.


METHODS
Idealized patients were used in the three groups of the proportional hypertensive models.


RESULTS
Previous studies demonstrated that the Bias, Precision, and Accuracy of Cardiac Output measurement, compared to Thermodilution technique, resulted in statistically acceptable clinical values.


CONCLUSIONS
This research has successfully demonstrated, with the use of the NHA, the leading role of Pulse Pressure in normal and hypertensive patients. We are convinced that this technique can be used as an economical and time-saving alternative screening tool in clinical medicine.
Kabal
John
J
Reston Noninvasive Hemodynamic Center, 1712 Clubhouse Road, Suite 103, Reston, VA 20190, USA. cardiopuls@msn.com
Lagerman
Bruce K
BK
D001794:Blood Pressure; D006973:Hypertension; D008954:Models, Biological