[Continuous subcutaneous infusion of apomorphine for the treatment of Parkinson's disease].
Apomorphine administered by subcutaneous infusion has been used efficiently in parkinsonian patients to treat severe motor fluctuations and levodopa-induced dyskinesias. Despite increasing evidence of its efficacy and its relative safety, apomorphine infusion therapy is still underused. This article reviews pharmacokinetic properties, efficacy, tolerability and indications of apomorphine infusion in Parkinson's disease.
Drapier
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Service de Neurologie, CHU de Rennes, Hôpital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes Cedex, France.
Vérin
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D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001058:Apomorphine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007263:Infusions, Parenteral; D010300:Parkinson Disease / Q000188:drug therapy*; D016896:Treatment Outcome
D000978:Antiparkinson Agents; D001058:Apomorphine