[Hepatopulmonary syndrome in a patient with adenocarcinoma of the colon metastatic to the liver and no apparent chronic liver disease].
Hepatopulmonary syndrome consists of a clinical triad: arterial blood deoxygenation, intrapulmonary vasodilation, and liver disease. Both acute and chronic cases of this syndrome have been reported, and the most common cause is cirrhosis. The principle disease mechanism is dilation of the pulmonary blood vessels causing alterations in gas exchange. Increased pulmonary production of nitric acid has been implicated as the primary pathogenic mechanism of vasodilation although it has also been associated with imbalance between vasodilators and vasoconstrictors. We describe the case of a patient with hepatopulmonary syndrome and adenocarcinoma of the colon with metastases to a previously healthy liver.
Vila Auli
Brian
B
Servicio de Neumología, Hospital Clínico Universitario de Valencia, Valencia, España.
Pérez García
Diego
D
Fernández Rodríguez
Conrado
C
Bañuls Polo
Pilar
P
Marín Pardo
Julio
J
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary*; D003106:Colon / Q000000981:diagnostic imaging / Q000473:pathology; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D003113:Colonoscopy; D020065:Hepatopulmonary Syndrome / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed