title: Multifocal biliary cystadenocarcinoma of the liver: CT and pathologic findings.
abstract: Biliary cystadenocarcinoma is a rare tumor that originates from the hepatobiliary epithelium. Although this tumor can affect any portion of the biliary tree, intrahepatic location is more common. It is usually a slow growing tumor and often asymptomatic until it reaches a considerable size. The lesion is most often solitary and large when discovered; multiple lesions or metastases within the liver are very rare. A 63-year-old man was referred to our institute for weight loss, abdominal discomfort, worsening bulky symptoms in the right upper abdominal quadrant, and an increase in serum aminotransferases that had been present for several months. Spiral CT of the abdomen demonstrated two lesions, a larger one and a distant intrahepatic lesion, with a multiloculated cystic aspect, a thin peripheral capsule, multiple solid peripheral portions, and irregular septa enhancing in the portal phase after intravenous administration of iodinated contrast medium. The diagnosis of multifocal cystadenocarcinoma of the liver was confirmed by surgical laparoscopy and biopsy of the lesion. The patient was treated with chemotherapy.
authors.affiliation: Sezione di Radiologia, DIBIMEL, Università degli Studi di Palermo, Palermo, Italy. sergio.salerno@unipa.it
authors.forename: Sergio
authors.initials: S
authors.lastname: Salerno
authors.forename: Ada Maria
authors.initials: AM
authors.lastname: Florena
authors.forename: Ida
authors.initials: I
authors.lastname: Romano
authors.forename: Laura
authors.initials: L
authors.lastname: Miceli
authors.forename: Antonio
authors.initials: A
authors.lastname: Lo Casto
mesh_terms: D001661:Biliary Tract Neoplasms / Q000000981:diagnostic imaging* / Q000201:enzymology / Q000473:pathology*; D001662:Biliary Tract Surgical Procedures / Q000379:methods; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003536:Cystadenocarcinoma / Q000000981:diagnostic imaging* / Q000201:enzymology / Q000473:pathology*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed; D000637:Transaminases / Q000097:blood
chemical_list: D000637:Transaminases