title: Paravertebral ropivacaine, 0.3%, and bupivacaine, 0.25%, provide similar pain relief after thoracotomy.
abstract: OBJECTIVE
  This study was designed to determine whether ropivacaine plus fentanyl was as effective as bupivacaine plus fentanyl in a continuous thoracic paravertebral block after posterolateral thoracotomy.
  
  
  METHODS
  Patients were randomly assigned in a blinded fashion to receive 1 of 2 solutions for paravertebral analgesia.
  
  
  METHODS
  Multi-institutional university hospital.
  
  
  METHODS
  Sixty patients undergoing elective thoracotomy.
  
  
  METHODS
  A continuous paravertebral infusion of 0.1 mL/kg/h of either 0.3% ropivacaine/fentanyl, 3 microg/mL, or 0.25% bupivacaine/fentanyl, 3 microg/mL, was started on admission to the intensive care unit.
  
  
  RESULTS
  Pain scores (rest, deep breathing, and coughing), spirometry, subcutaneous opioids, or nonsteroidal anti-inflammatory drug consumption and adverse events were assessed for 48 hours. Both techniques provided adequate pain relief for the first 2 days after posterolateral thoracotomy. There were no differences between groups in pain scores at rest, coughing, or movement. There was an improvement of spirometry values between the first and second day in both groups. There were no differences in the requirements for rescue analgesia and side effects between groups.
  
  
  CONCLUSIONS
  It is concluded that both bupivacaine, 0.25%, and ropivacaine, 0.3%, with fentanyl are equally effective for post-thoracotomy pain control when used via continuous paravertebral blockade.
authors.affiliation: Department of Anesthesiology, Gregorio Marañón General Hospital, Madrid, Spain. martagnavlet@hotmail.com <martagnavlet@hotmail.com>
authors.forename: Marta García
authors.initials: MG
authors.lastname: Navlet
authors.forename: Ignacio
authors.initials: I
authors.lastname: Garutti
authors.forename: Luis
authors.initials: L
authors.lastname: Olmedilla
authors.forename: Jose María
authors.initials: JM
authors.lastname: Pérez-Peña
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: San Joaquin
authors.forename: Gemma
authors.initials: G
authors.lastname: Martinez-Ragues
authors.forename: Leticia
authors.initials: L
authors.lastname: Gomez-Caro
mesh_terms: D000577:Amides / Q000008:administration & dosage*; D000698:Analgesia / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005541:Forced Expiratory Volume; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000503:physiopathology / Q000517:prevention & control*; D011182:Postoperative Care / Q000379:methods*; D011446:Prospective Studies; D000077212:Ropivacaine; D013127:Spinal Nerves; D013147:Spirometry; D013908:Thoracotomy; D016896:Treatment Outcome
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D002045:Bupivacaine