title: Canine ovarian serous papillary adenocarcinoma with neoplastic hypercalcemia.
abstract: A female golden retriever was referred to assess a history of a palpable abdominal mass. A serum chemistry analysis revealed elevated concentrations of blood urea nitrogen, creatinine, calcium, and parathyroid hormone-related protein (PTH-rP). Exploratory laparotomy revealed an ovoid mass within the right ovary. This mass was removed surgically by performing an ovariohysterectomy. The right ovarian mass was diagnosed as a serous papillary adenocarcinoma. Following surgery, the dog recovered, and the serum calcium and PTH-rP concentrations decreased. Therefore, concentrations of PTH-rP and calcium might be associated with serous papillary adenocarcinomas. Serial evaluation of the serum PTH-rP and calcium was useful for evaluating the prognosis.
authors.affiliation: Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan.
authors.forename: Yasutomo
authors.initials: Y
authors.lastname: Hori
authors.forename: Masami
authors.initials: M
authors.lastname: Uechi
authors.forename: Kayo
authors.initials: K
authors.lastname: Kanakubo
authors.forename: Tadashi
authors.initials: T
authors.lastname: Sano
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Oyamada
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000209:etiology*; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*