[Modification of a catalase by glutaraldehyde].
Polycondensation of a catalase (EC 1.11.1.6) with glutaraldehyde in order to stabilize the quaternary structure of an enzyme, maintain its activity, and protect it from thermal denaturation was studied. Synthesis showed a superequivalent utilization of the aldehyde groups relative to the catalase amine groups, as a result of the formation of glutaraldehyde oligomers linked to the enzyme.
Mishaeva
R N
RN
Gudkin
L R
LR
Kuznetsov
N P
NP
D000818:Animals; D002374:Catalase / Q000737:chemistry*; D002417:Cattle; D003432:Cross-Linking Reagents / Q000737:chemistry*; D005976:Glutaral / Q000737:chemistry*; D011489:Protein Denaturation; D020836:Protein Structure, Quaternary
D003432:Cross-Linking Reagents; D002374:Catalase; D005976:Glutaral