title: Replicative helicases: a staircase with a twist.
abstract: The first crystal structure of a ring helicase encircling single-stranded DNA reveals a mechanism for ATP-dependent DNA translocation.
authors.affiliation: Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK. Mark.Dillingham@bristol.ac.uk
authors.forename: Mark S
authors.initials: MS
authors.lastname: Dillingham
mesh_terms: D000244:Adenosine Diphosphate / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000378:metabolism; D052688:Bovine papillomavirus 1 / Q000235:genetics*; D018360:Crystallography, X-Ray; D004265:DNA Helicases / Q000737:chemistry*; D004261:DNA Replication / Q000502:physiology*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D004268:DNA-Binding Proteins / Q000737:chemistry*; D008957:Models, Genetic; D008958:Models, Molecular; D014764:Viral Proteins / Q000737:chemistry*
chemical_list: D004277:DNA, Single-Stranded; D004268:DNA-Binding Proteins; C069814:E1 protein, Bovine papillomavirus; D014764:Viral Proteins; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D004265:DNA Helicases