title: A randomized controlled trial of cognitive behavior therapy for borderline personality disorder: rationale for trial, method, and description of sample.
abstract: This paper describes the rationale for a randomized controlled trial, comparing cognitive behavior therapy in addition to treatment as usual with treatment as usual alone, for borderline personality disorder. Previous pioneering randomized controlled trials of psychotherapies have suffered from methodological weaknesses and have not always been reported clearly to allow adequate evaluation of either the individual study or comparisons across studies to be undertaken. We report on the recruitment and randomization, design, and conduct of an ongoing randomized controlled trial of one hundred and six patients with borderline personality disorder. Primary and secondary hypotheses and their planned analyses are stated. The baseline characteristics of 106 patients meeting diagnostic criteria for borderline personality disorder are described.
authors.affiliation: Psychological Medicine, University of Glasgow. k.davidson@clinmed.gla.ac.uk
authors.forename: Kate
authors.initials: K
authors.lastname: Davidson
authors.forename: Peter
authors.initials: P
authors.lastname: Tyrer
authors.forename: Andrew
authors.initials: A
authors.lastname: Gumley
authors.forename: Philip
authors.initials: P
authors.lastname: Tata
authors.forename: John
authors.initials: J
authors.lastname: Norrie
authors.forename: Stephen
authors.initials: S
authors.lastname: Palmer
authors.forename: Humera
authors.initials: H
authors.lastname: Millar
authors.forename: Leigh
authors.initials: L
authors.lastname: Drummond
authors.forename: Helen
authors.initials: H
authors.lastname: Seivewright
authors.forename: Heather
authors.initials: H
authors.lastname: Murray
authors.forename: Fiona
authors.initials: F
authors.lastname: Macaulay
mesh_terms: D000328:Adult; D000368:Aged; D001883:Borderline Personality Disorder / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011369:Professional-Patient Relations; D011569:Psychiatric Status Rating Scales; D012107:Research Design; D016896:Treatment Outcome