title: Predictors of long-term survival with pulmonary metastasectomy for osteosarcomas and soft tissue sarcomas.
abstract: OBJECTIVE
  The control of pulmonary metastases is important for long-term survival of the patients with osteosarcomas and soft tissue sarcomas.
  
  
  METHODS
  To evaluate the efficacy of aggressive pulmonary metastasectomy for those patients, we reviewed 105 cases (44 osteosarcomas, and 61 soft tissue sarcomas) treated in our hospital.
  
  
  RESULTS
  The number of metastases was only the significant risk factor for the curability of the metastasectomy (logistic regression analysis, P=0.0274). The 5-year and 10-year survival rate were 43.6% and 32%. The curability was only independent prognostic factor on multivariate analysis (P=0.0008).
  
  
  CONCLUSIONS
  Early detection of pulmonary metastasis, multimodal perioperative treatment, and design for minimizing the volume of resected lung tissues will enable complete and repeat resections for the achievement of long-term survival.
authors.affiliation: Division of Thoracic Diseases, Chiba Cancer Center, Chiba, Japan. smakoto@faculty.chiba-u.jp
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Iwata
authors.forename: S
authors.initials: S
authors.lastname: Ando
authors.forename: T
authors.initials: T
authors.lastname: Iida
authors.forename: T
authors.initials: T
authors.lastname: Nakajima
authors.forename: T
authors.initials: T
authors.lastname: Ishii
authors.forename: T
authors.initials: T
authors.lastname: Yonemoto
authors.forename: S
authors.initials: S
authors.lastname: Tatezaki
authors.forename: T
authors.initials: T
authors.lastname: Fujisawa
authors.forename: H
authors.initials: H
authors.lastname: Kimura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000401:mortality / Q000556:secondary / Q000601:surgery; D011013:Pneumonectomy / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D012509:Sarcoma / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D015996:Survival Rate; D013997:Time Factors