title: [Synthesis and antibacterial activity of new polyfluoro-1,3,5-oxadiazines].
abstract: A number of polyfluro-3,6-dihydro-2H-1,3,5-oxadiazines and polyfluoro-4H-1,3,5-oxadiazines was designed. Relationship between their chemical structure and in vitro activity was investigated. The highest activity against grampositive microorganisms was shown by N1,N6-bis-[2,2,6,6-tetrakis(trifluoromethyl)-3,6-dihydro-2H-1,3,5-oxadiazine-4-yl]-1,6-hexane diamine.
authors.forename: S V
authors.initials: SV
authors.lastname: Sidorenko
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Kriukova
authors.forename: A B
authors.initials: AB
authors.lastname: Zhiganov
authors.forename: L N
authors.initials: LN
authors.lastname: Kriukov
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; C515380:N(1),N(6)-bis(2,2,6,6-tetrakis(trifluoromethyl)-3,6-dihydro-2H-1,3,5-oxadiazine-4-yl)-1,6-hexanediamine; D010078:Oxazines