title: Early outcomes of out-of-hospital cardiac arrest after early defibrillation: a 24 months retrospective analysis.
abstract: BACKGROUND
  Cardiovascular disease remains the most common cause of death in the United States and most other Western nations. Among these deaths, sudden, out-of-hospital cardiac arrest claims approximately 1000 lives each day in the United States alone. Most of these cardiac arrests are due to ventricular fibrillation. Though highly reversible with the rapid application of a defibrillator, ventricular fibrillation is otherwise fatal within minutes, even when cardiopulmonary resuscitation is provided immediately. The overall survival rate in the United States is estimated to be less than 5 percent. Recent developments in automated-external-defibrillator technology have provided a means of increasing the rate of prompt defibrillation after out-of-hospital cardiac arrest. After minimal training, nonmedical personnel (e.g., flight attendants and casino workers) are also able to use defibrillators in the workplace, with lifesaving effects. Nonetheless, such programs have involved designated personnel whose job description includes assisting persons who have had sudden cardiac arrest. Data are still lacking on the success of programs in which automated external defibrillators have been installed in public places to be used by persons who have no specific training or duty to act.
  
  
  METHODS
  All patients who had an out-of-hospital cardiac arrest between January 2003 and December 2004 and who received early defibrillation for ventricular fibrillation were included. We conducted a 24 months retrospective population-based analysis of the outcome in our population.
  
  
  RESULTS
  Over a 24 month period, 446 people had non-traumatic cardiac arrest, and in all of them it was observed to be ventricular fibrillation. In a very few cases, the defibrillator operators were good Samaritans, acting voluntarily. Eighty-nine patients (about 19%) with ventricular fibrillation were successfully resuscitated, including eighteen who regained consciousness before hospital admission.
  
  
  CONCLUSIONS
  Automated external defibrillators deployed in readily accessible, well-marked areas, are really very effective in assisting patients with cardiac arrest. However, it's quite true that, in the cases of survivors, most of our users had good prior training in the use of these devices.
authors.affiliation: Divisione e Cattedra di Cardiologia, Dipartimento di Medicina, Chirurgia e Odontoiatria dell'Universita degli Studi di Milano, Azienda Ospedaliera S. Paolo - Polo Universitario, Italy. terranovapaolo@hotmail.com
authors.forename: Paolo
authors.initials: P
authors.lastname: Terranova
authors.forename: Paolo
authors.initials: P
authors.lastname: Valli
authors.forename: Barbara
authors.initials: B
authors.lastname: Severgnini
authors.forename: Simonetta
authors.initials: S
authors.lastname: Dell'Orto
authors.forename: Greco
authors.initials: G
authors.lastname: Enrico Maria