Gastrointestinal tract involvement in Langerhans cell histiocytosis: case report and literature review.
Digestive tract involvement in Langerhans cell histiocytosis is exceedingly rare. We report a case of Langerhans cell histiocytosis in an otherwise thriving neonate presenting with hematochezia, anemia, and rash. We also review the few cases of Langerhans cell histiocytosis with gastrointestinal involvement reported in the English-language medical literature. Although gastrointestinal involvement can range in severity from mild to life-threatening, its presence may be indicative of multisystemic disease, and aggressive treatment should be considered.
Hait
Elizabeth
E
Children's Hospital Boston, Division of Gastroenterology and Nutrition, 300 Longwood Ave, Boston, MA 02115, USA.
Liang
Marilyn
M
Degar
Barbara
B
Glickman
Jonathan
J
Fox
Victor L
VL
D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D007223:Infant