Rhodium-catalysed addition of organotrialkoxysilanes to alpha-substituted acrylic esters.
The cationic rhodium complex [Rh(cod)2][BF4] effectively catalyses the 1,4-addition of organotrialkoxysilanes to alpha-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and alpha-amino acid derivatives.
Hargrave
Jonathan D
JD
Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Herbert
Jennifer
J
Bish
Gerwyn
G
Frost
Christopher G
CG
D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008670:Metals; D008958:Models, Molecular; D008968:Molecular Conformation; D053644:Naphthalimides / Q000737:chemistry; D009930:Organic Chemicals / Q000138:chemical synthesis*; D012238:Rhodium; D012821:Silanes / Q000737:chemistry*
D004952:Esters; D008670:Metals; D053644:Naphthalimides; D009930:Organic Chemicals; D012821:Silanes; D012238:Rhodium