Cucurbitane glycosides from unripe fruits of Lo Han Kuo (Siraitia grosvenori).
From the unripe fruits of Lo Han Kuo (Siraitia grosvenori), a Chinese medicinal plant, two new cucurbitane triterpene glycosides, 20-hydroxy-11-oxomogroside IA(1) (1) and 11-oxomogroside IIE (2), were isolated along with five known cucurbitane glycosides, 11-oxomogroside IA(1) (3), mogroside IIE (4), mogroside III (5), mogroside IVA (6), and mogroside V (7), and two flavonoid glycosides, kaempferol 7-O-alpha-L-rhamnopyranoside (8) and kaempferol 3,7-di-O-alpha-L-rhamnopyranoside (9). Their structures were determined on the basis of detailed analyses of 1D, 2D-NMR spectroscopic methods and by comparing with literature values. This paper describes the first investigation of unripe bitter Lo Han Kuo fruits.
Li
Dianpeng
D
Faculty of Medical and Pharmaceutical Science, Kumamoto University, Kumamoto, Japan.
Ikeda
Tsuyoshi
T
Matsuoka
Nanae
N
Nohara
Toshihiro
T
Zhang
Hourui
H
Sakamoto
Tatsunori
T
Nonaka
Gen-Ichiro
G
D019662:Cucurbitaceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008968:Molecular Conformation; D012015:Reference Standards; D012680:Sensitivity and Specificity; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D004365:Drugs, Chinese Herbal; D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane