title: Surgery in advanced and metastatic renal cell carcinoma.
abstract: Curative surgery in more advanced renal cell carcinoma is limited to solitary metastases or regional disease. Response to systemic immunotherapy continues to be reported; however, most responses are limited and not durable. Only randomized, prospective clinical trials will prove the efficacy of systemic therapy.
authors.affiliation: James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
authors.forename: D Y
authors.initials: DY
authors.lastname: Chan
authors.forename: F F
authors.initials: FF
authors.lastname: Marshall