title: [Interactions between dopamine, serotonin and other internal reinforcement factors].
abstract: The big volume of odd literature data (period 1960-2005) was investigated for analysis and estimation of interactions between dopamine (DA), serotonin (5-HT), reward factors and basic members of regulatory peptide (RP) families. Database, which includes information about physiological effect directions, doses and administration types of RP and biological active compounds, organism types, organ-tissues systems and receptor mechanisms was created. The complex cascade interactions between DA, 5-HT, reward factors and RP were investigated and systemized. Based on analysis of correlated functiong of DA and 5-HT-systems, the opponent-reciprocal interactions were established and their integrative characteristics were estimated.
authors.forename: S V
authors.initials: SV
authors.lastname: Koroleva
authors.forename: A A
authors.initials: AA
authors.lastname: Nikolaeva
authors.forename: I P
authors.initials: IP
authors.lastname: Ashmarin
mesh_terms: D000818:Animals; D016208:Databases, Factual; D004298:Dopamine / Q000502:physiology*; D015259:Dopamine Agents / Q000494:pharmacology; D006801:Humans; D010455:Peptides / Q000494:pharmacology / Q000502:physiology*; D012054:Reinforcement, Psychology; D012701:Serotonin / Q000502:physiology*; D015398:Signal Transduction
chemical_list: D015259:Dopamine Agents; D010455:Peptides; D012701:Serotonin; D004298:Dopamine