MK-0518 and GS-9137: two promising integrase inhibitors in the pipeline.
Possibly the most exciting news to come out of the 13th Conference on Retroviruses and Opportunistic Infections, held in Denver last February, concerned clinical trials of two experimental drugs in a new class: integrase inhibitors. If successful in further trials, integrase inhibitors could revitalize the treatment regimens of people living with multidrug-resistant HIV.
O'Neal
Reilly
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D024882:Drug Resistance, Viral; D019428:HIV Integrase Inhibitors / Q000627:therapeutic use*; D009930:Organic Chemicals / Q000627:therapeutic use*; D011760:Pyrrolidinones; D015363:Quinolones / Q000627:therapeutic use*; D000068898:Raltegravir Potassium; D019562:Viral Load
D019428:HIV Integrase Inhibitors; D009930:Organic Chemicals; D011760:Pyrrolidinones; D015363:Quinolones; D000068898:Raltegravir Potassium; C509700:elvitegravir