Pregnancy-induced pancytopenia with cellular bone marrow: distinctive hematologic features.
Three patients with pregnancy-induced pancytopenia also exhibited variable features of sideroblastic anemia and amegakaryocytic thrombocytopenia. Treatment with anti-thymocyte globulin proved highly effective in two cases and a spontaneous remission occurred in the third. This illness is distinct from the more commonly reported incidental association of pregnancy with classic aplastic anemia. Its differentiation from myelodysplasia is also emphasized.
Natelson
Ethan A
EA
Methodist Academic Medicine Associates, The Methodist Hospital, Houston, Texas 77030, USA. enatelson@tmh.tmc.edu
D000328:Adult; D000741:Anemia, Aplastic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D000756:Anemia, Sideroblastic / Q000188:drug therapy / Q000473:pathology; D000961:Antilymphocyte Serum / Q000008:administration & dosage*; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008533:Megakaryocytes / Q000473:pathology; D010198:Pancytopenia / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy* / Q000473:pathology
D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents