Etanercept therapy for silicone granuloma.
A patient developed a typical, painful, and debilitating reaction on the thighs following injection of ostensibly medical grade "silicone" to achieve alteration of body contours. The refractory silicone granuloma responded dramatically to treatment with etanercept.
Desai
Anupam M
AM
Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
Browning
John
J
Rosen
Theodore
T
D003357:Cosmetic Techniques / Q000009:adverse effects*; D003937:Diagnosis, Differential; D000068800:Etanercept; D015745:Granuloma, Foreign-Body / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use*; D020034:Silicone Gels / Q000008:administration & dosage / Q000009:adverse effects*; D013848:Thigh / Q000473:pathology; D014189:Transsexualism; D014409:Tumor Necrosis Factor-alpha
D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins; D020034:Silicone Gels; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept