Kawasaki disease: summary of the American Heart Association guidelines.
Kawasaki disease is an acute vasculitis of childhood that predominantly affects the coronary arteries. The etiology of Kawasaki disease remains unknown, although an infectious agent is strongly suspected based on clinical and epidemiologic features. A genetic predisposition is also likely, based on varying incidences among ethnic groups, with higher rates in Asians. Symptoms include fever, conjunctival injection, erythema of the lips and oral mucosa, rash, and cervical lymphadenopathy. Some children with Kawasaki disease develop coronary artery aneurysms or ectasia, ischemic heart disease, and sudden death. Kawasaki disease is the leading cause of acquired heart disease among children in developed countries. This article provides a summary of the diagnostic and treatment guidelines published by the American Heart Association.
Freeman
Alexandra F
AF
National Institutes of Health, Bethesda, Maryland, USA.
Shulman
Stanford T
ST
D002648:Child; D003323:Coronary Aneurysm / Q000209:etiology; D006801:Humans; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D009203:Myocardial Infarction / Q000209:etiology; D017410:Practice Guidelines as Topic; D018570:Risk Assessment