Macromolecular assemblies based on coupled inclusion complex and electrostatic interactions.
Macromolecular assemblies are elaborated by mixing beta-cyclodextrin-containing polymer (polybetaCD), dextran sulfate polyanion (NaDxS), and cationic amphiphiles which are adamantane derivatives (Ada1 or Ada2) in aqueous medium. These components are assembled via coupled inclusion complex interactions (adamantyl group with cyclodextrin cavity) and electrostatic attractive interactions (positive charges of Ada with negative charge of NaDxS). The structural properties are studied by viscometry and small angle neutron scattering. Ternary aggregates with larger size and lower compacities are observed as the cation concentration is increased, until phase separation occurs. The results are in good agreement with a core-shell association mechanism, the core being made of one polybetaCD chain, the shell of NaDxS chains, and the Ada amphiphiles being distributed more or less homogeneously inside the cyclodextrin cavities. The nature of the Ada counterions has a strong influence on the association as Ada1 with I(-) counterions give smaller and less compact aggregates than Ada2 with Br(-) counterions.
Burckbuchler
Virginie
V
Laboratoire de Recherche sur les Polymères, LRP, C.N.R.S. UMR 7581, 2-8 rue Henri Dunant, 94320 Thiais, France.
Boutant
Valérie
V
Wintgens
Véronique
V
Amiel
Catherine
C
D001667:Binding, Competitive; D001709:Biotechnology / Q000379:methods*; D003505:Cyclodextrins / Q000737:chemistry; D016264:Dextran Sulfate / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods*; D007477:Ions; D007700:Kinetics; D046911:Macromolecular Substances; D008856:Microscopy, Fluorescence; D008956:Models, Chemical; D009502:Neutrons; D011108:Polymers / Q000737:chemistry; D012542:Scattering, Radiation; D055672:Static Electricity; D047392:beta-Cyclodextrins / Q000737:chemistry
D003505:Cyclodextrins; D007477:Ions; D046911:Macromolecular Substances; D011108:Polymers; D047392:beta-Cyclodextrins; D016264:Dextran Sulfate; C031215:betadex