Molecular evolution of the H-NS protein: interaction with Hha-like proteins is restricted to enterobacteriaceae.
We show here that chromosomal hha-like genes are restricted to the Enterobacteriaceae. The H-NS N-terminal domain of members of this family includes an unaltered seven-amino-acid sequence located between helixes 1 and 2, termed the Hha signature, that contains key residues for H-NS-Hha interaction.
Madrid
Cristina
C
Department of Microbiology, University of Barcelona, Avda. Diagonal 645, 08028 Barcelona, Spain.
García
Jesús
J
Pons
Miquel
M
Juárez
Antonio
A
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D004755:Enterobacteriaceae / Q000235:genetics*; D029968:Escherichia coli Proteins / Q000378:metabolism; D019143:Evolution, Molecular; D008969:Molecular Sequence Data; D010802:Phylogeny; D016415:Sequence Alignment; D013045:Species Specificity
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C031908:H-NS protein, bacteria; C079209:hha protein, E coli