title: [Fetal ischaemic brain injury in the second trimester of pregnancy].
abstract: Based on clinical, epidemiologic, and experimental studies, the aetiology of white matter damage, specially periventricular leukomalacia (PVL), is multifactorial and involves pre- and perinatal factors. Each of these factors is supposed to be a major precursor for neurological and intellectual impairment, and cerebral palsy (CP) in later life. Antenatal rather than intrapartum factors are now emerging as the major determinants of cerebral palsy. In this case report maternal trauma, benign tumour, severe anaemia and fetal cerebral vascular malformation are supposed as causative factors in intrauterine periventricular leukomalacia resulting from hypoxic-ischaemic injury.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar, I Szülészeti és Nogyógyászati Klinika, Budapest. gavai@noi1.sote.hu
authors.forename: Márta
authors.initials: M
authors.lastname: Gávai
authors.forename: Valéria
authors.initials: V
authors.lastname: Váradi
authors.forename: Zorán
authors.initials: Z
authors.lastname: Belics
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Papp
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000150:complications* / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D002532:Intracranial Aneurysm / Q000209:etiology; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal