[Treatment of influenza virus infection with anti-virals].
Dramatic advances have been made in the diagnosis and treatment of influenza in Japan in recent years. Most patients with influenza-like illness are now tested with rapid diagnostic tests, and if the results are positive, they are treated with neuraminidase inhibitors, mostly oseltamivir. However, we experienced emergence of resistant strains to oseltamivir and variable side effects. Zanamivir will be used widely in Japan, because it is characterized of lower rate of resistance. Stockpiling of those antivirals is essential for pandemic preparedness plan.
Sugaya
Norio
N
Department of Pediatrics, Keiyu Hospital.
D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy*; D009439:Neuraminidase / Q000037:antagonists & inhibitors
D000998:Antiviral Agents; D009439:Neuraminidase