title: Remodeling of the thoracic aorta after stent grafting of type B dissection: a Swedish multicenter study.
abstract: OBJECTIVE
  Endovascular repair of complicated type B dissections has evolved as a promising alternative to open repair. Previous studies have indicated that continued false lumen flow is a predictor of continued aortic dilatation and risk of rupture during follow-up. This multicenter study was conducted to analyze the postoperative changes of the false lumen after endografting of complicated type B dissections.
  
  
  METHODS
  All patients treated with endovascular stent grafts for thoracic type B dissections at 5 major Vascular Centers in Sweden were identified through local databases. Review of charts and all available pre- and postoperative CT scans were performed to identify demographics, indications for repair as well as postoperative changes of the aorta and false lumen.
  
  
  RESULTS
  A total of 129 patients treated for type B dissections between 1994 and December 2005 were identified. Median radiological follow-up was 14 months. Fourteen patients died perioperatively leaving 115 patients available for analysis. Seventy-four of these had CT imaging of sufficient quality for morphological analysis. The vast majority of acute patients were treated for rupture or end-organ ischemia whereas most chronic patients were treated for asymptomatic aneurysms. In 80% of patients, the false lumen thrombosed along the stent graft but it remained perfused distal to the stent graft fixation in 50% of patients. Only 5% of patients presented with aortic enlargement of the stent grafted area when adequate proximal sealing was achieved. The distal, uncovered aorta displayed expansion in 16% of patients.
  
  
  CONCLUSIONS
  The stent grafted thoracic aorta after type B dissection appears to be stabilized by covering the primary entry site with a stent graft in the majority of both acute and chronic dissections. The uncovered portion of the aorta distal to the stent graft, however, remains at risk of continuous dilatation. Stent grafting for complicated type B thoracic dissections seems to be a treatment option with reasonable morbidity and mortality even though the incidence of severe complications is still significant.
authors.affiliation: Department of Vascular Diseases, Malmö University Hospital, Malmö, Sweden. timothyresch@gmail.com
authors.forename: T A
authors.initials: TA
authors.lastname: Resch
authors.forename: M
authors.initials: M
authors.lastname: Delle
authors.forename: M
authors.initials: M
authors.lastname: Falkenberg
authors.forename: K
authors.initials: K
authors.lastname: Ivancev
authors.forename: P
authors.initials: P
authors.lastname: Konrad
authors.forename: T
authors.initials: T
authors.lastname: Larzon
authors.forename: L
authors.initials: L
authors.lastname: Lönn
authors.forename: M
authors.initials: M
authors.lastname: Malina
authors.forename: R
authors.initials: R
authors.lastname: Nyman
authors.forename: B
authors.initials: B
authors.lastname: Sonesson
authors.forename: S
authors.initials: S
authors.lastname: Thelin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D012086:Reoperation; D012189:Retrospective Studies; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome