Two-directional synthesis and stereochemical assignment toward a C2 symmetric oxasqualenoid (+)-intricatetraol.
The asymmetric synthesis of tetraol (+)-3, a degradation product derived from a C2 symmetric oxasqualenoid intricatetraol 1, has been achieved through the two-directional synthesis starting from diol 7, realizing the further additional assignment of the incomplete stereostructure of 1, the stereochemistry of which is difficult to determine otherwise.
Morimoto
Yoshiki
Y
Department of Chemistry, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan. morimoto@sci.osaka-cu.ac.jp
Takaishi
Mamoru
M
Adachi
Noriko
N
Okita
Tatsuya
T
Yata
Hiromi
H
D000438:Alcohols / Q000138:chemical synthesis / Q000737:chemistry; D004852:Epoxy Compounds / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D013185:Squalene / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
D000438:Alcohols; D004852:Epoxy Compounds; C523058:oxasqualenoid-intricatetraol; D013185:Squalene