title: Preoperative autologous blood donation by arthritis patients is associated with preoperative anemia and perioperative transfusion.
abstract: BACKGROUND
  Preoperative autologous blood donation (PAD) became a common practice in the 1990s in an attempt to reduce the risk of transmission of infectious agents from allogeneic blood. However, a potential risk of PAD is the development of preoperative anemia that may lead, in turn, to an enhanced need for transfusion. Furthermore, the ready availability of autologous blood may predispose to more liberal transfusion peri-/postoperatively.
  
  
  OBJECTIVE
  To examine these hypotheses, we retrospectively examined a cohort of knee and hip arthroplasty patients.
  
  
  METHODS
  Charts of patients of 2 orthopedic surgeons from the mid 1980s and 1990s were reviewed for transfusions needed and hematocrits before and after arthroplasties.
  
  
  RESULTS
  PAD proved to be a significant risk factor for the development of preoperative anemia and for peri-/postoperative blood transfusion even after adjusting for confounders.
  
  
  CONCLUSIONS
  These results suggest that PAD may lead to a self-defeating cycle of blood donation followed by blood transfusion. With the improved safety of the allogeneic blood supply, rheumatologists may want to play a more active role in considering PAD in patients in whom elective arthroplasty is planned.
authors.affiliation: Division of Rheumatology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA. ssule@jhmi.edu
authors.forename: Sangeeta D
authors.initials: SD
authors.lastname: Sule
authors.forename: Susan
authors.initials: S
authors.lastname: Bartlett
authors.forename: Antigone
authors.initials: A
authors.lastname: Parker
authors.forename: Michael
authors.initials: M
authors.lastname: Dorsi
authors.forename: Marilyn
authors.initials: M
authors.lastname: Towns
authors.forename: Joan
authors.initials: J
authors.lastname: Bathon