title: Left ventricular myocardal activation under ventricular paced beats in chickens Gallus gallus domesticus.
abstract: The aim of the study was to advance our knowledge regarding the activation process of the ventricular myocardium in birds in which Purkinje fibres penetrate into the ventricular wall to reach the epicardium. A depolarization pattern of the left ventricular free wall was studied in chickens (Gallus gallus) during ventricular paced beats. Duration of the activation process of the left ventricular free wall is significantly increased during ventricular ectopic excitation as compared with sinus rhythm. Its lowest increase occurs during subendocardial pacing of the middle part of the left ventricle, but its greatest increase is observed during subepicardial pacing of the left ventricular base. Multifocality and mosaicity of depolarization of the left ventricular free wall myocardium in chicken are expressed in a considerably less degree during ventricular paced beats in comparison with sinus rhythm. During ventricular paced beats, excitation of the left ventricular free wall is mostly due to the successive spreading of the depolarization wave from pacing sites.
authors.affiliation: Laboratory of Cardiac Physiology, Institute of Physiology, Komi Science Centre, Ural Branch of the Russian Academy of Sciences, 50 Pervomayskaya st., 167000, Syktyvkar, Komi Republic, Russia. s.kharin@physiol.komisc.ru
authors.forename: Sergey
authors.initials: S
authors.lastname: Kharin
authors.forename: Nadezhda
authors.initials: N
authors.lastname: Antonova
authors.forename: Dmitry
authors.initials: D
authors.lastname: Shmakov
mesh_terms: D000818:Animals; D002304:Cardiac Pacing, Artificial; D002645:Chickens / Q000502:physiology*; D004562:Electrocardiography; D005260:Female; D016276:Ventricular Function; D016277:Ventricular Function, Left / Q000502:physiology*