Hypogonadotropism with elevated serum testosterone: reversible causes of secondary infertility.
BACKGROUND
A 33-year-old man presented with secondary infertility, increased libido, and extreme oligospermia. Testicular volumes were reduced, but no gynecomastia was apparent and androgen abuse was denied.


METHODS
Physical examination, semen-volume and sperm-density assessment, laboratory tests for serum levels of luteinizing hormone, follicle-stimulating hormone, testosterone, and dehydroepiandrosterone sulfate, karyotyping, testicular ultrasound, pelvic and abdominal CT, assessment for serum testicular tumor markers (alpha-fetoprotein and human chorionic gonadotropin), and histologic examination of testicular tissue.


METHODS
Benign Leydig-cell adenoma.


RESULTS
Left orchidectomy.
McLachlan
Robert I
RI
Prince Henry's Institute, Melbourne, Australia. rob.mclachlan@princehenrys.org
de Kretser
David M
DM
D000328:Adult; D006801:Humans; D007006:Hypogonadism / Q000097:blood* / Q000150:complications / Q000473:pathology; D007248:Infertility, Male / Q000097:blood* / Q000209:etiology / Q000473:pathology; D008297:Male; D013739:Testosterone / Q000097:blood*
D013739:Testosterone