Punding and dyskinesias.
The presence of punding in Parkinson's disease (PD) has been associated with inappropriate excessive use of dopaminergic medication but its relation to the severity of dyskinesias is not known. Through the use of clinical examination and medical chart review, the presence of punding and the severity of interdose dyskinesias were evaluated by two different observers. Punding was associated with more frequent interventions to reduce dyskinesias and with greater dyskinesia severity. We suggest the neural systems mediating the expression of dyskinesias and punding might overlap and that punding should be looked for systematically in PD patients presenting with disabling severe dyskinesias.
Silveira-Moriyama
Laura
L
Reta Lila Weston Institute of Neurological Studies, University College London, London, United Kingdom.
Evans
Andrew H
AH
Katzenschlager
Regina
R
Lees
Andrew J
AJ
D000368:Aged; D000369:Aged, 80 and over; D003710:Demography; D018491:Dopamine Agonists / Q000009:adverse effects; D004409:Dyskinesia, Drug-Induced / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy; D012720:Severity of Illness Index; D013239:Stereotyped Behavior / Q000502:physiology*
D018491:Dopamine Agonists; D007980:Levodopa