title: A case of recurrent episodes of Candida parapsilosis fungemia.
abstract: Candida species is the fourth most commonly isolated organism in blood stream infections in the hospital setting. Patients with candidemia frequently succumb to this infection. For those that survive an initial candidemia, an increasing number of cases of breakthrough or recurrent candidemias have been reported in the literature. We report three episodes of C. parapsilosis fungemia in a cancer patient. Molecular testing was performed and confirmed that all these episodes occurring within an eight-month period were caused by the same organism. The incidence of recurrent candidemia is likely to increase in the near future. Studies and therapeutic interventions for patients at risk for recurrent candidemias are warranted.
authors.affiliation: Division of Infectious Diseases and Environmental Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA. dionissios.neofytos@mail.tju.edu
authors.forename: Dionissios
authors.initials: D
authors.lastname: Neofytos
authors.forename: Michael A
authors.initials: MA
authors.lastname: Pfaller
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Diekema
authors.forename: David
authors.initials: D
authors.lastname: Horn
mesh_terms: D000230:Adenocarcinoma / Q000382:microbiology*; D002175:Candida / Q000254:growth & development*; D002177:Candidiasis / Q000382:microbiology*; D003110:Colonic Neoplasms / Q000382:microbiology*; D003428:Cross Infection / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence