Intrasellar paraganglioma: a case report and review of the literature.
Intrasellar paragangliomas are very rare lesions with only six previous cases described in the literature. We present a further case of intrasellar paraganglioma. The patient was a 52 yr-old man who developed two transient ischemic attacks. A CT scan showed an intra- and supra-sellar expanding lesion, which was regarded as a possible non-functioning pituitary macro-adenoma. Removal of the lesion was accomplished by transsphenoidal surgery. Histological examination was diagnostic of a paraganglioma. We review the literature and discuss pathological features and possible pathogenesis of sellar and parasellar paragangliomas, underlining the necessity to consider paraganglioma in the differential diagnosis of sellar lesions.
Boari
N
N
Department of Neurosurgery, San Raffaele Scientific Institute, University Vita-Salute, Milan, Italy. boari.nicola@hsr.it
Losa
M
M
Mortini
P
P
Snider
S
S
Terreni
M R
MR
Giovanelli
M
M
D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000378:metabolism; D019635:Neurosurgical Procedures; D010235:Paraganglioma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D010902:Pituitary Gland / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D014408:Biomarkers, Tumor; D009419:Nerve Tissue Proteins