title: Pacemaker infection due to Mycobacterium fortuitum: the role of universal 16S rRNA gene PCR and sequencing.
abstract: Rapidly growing mycobacteria are a rare cause of pacemaker infection. A low index of suspicion and conventional diagnostic methods may delay diagnosis. We present a review of the literature and report a case of pacemaker infection due to Mycobacterium fortuitum rapidly detected by universal 16S rRNA gene polymerase chain reaction and sequencing.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
authors.forename: Maddalena
authors.initials: M
authors.lastname: Giannella
authors.forename: Maricela
authors.initials: M
authors.lastname: Valerio
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Franco
authors.forename: Mercedes
authors.initials: M
authors.lastname: Marin
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
authors.forename: Patricia
authors.initials: P
authors.lastname: Muñoz
mesh_terms: D000369:Aged, 80 and over; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D005260:Female; D006801:Humans; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000235:genetics*; D019907:Mycobacterium fortuitum / Q000235:genetics* / Q000472:pathogenicity*; D010138:Pacemaker, Artificial / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000145:classification*; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S