title: Micropatterning of porous silicon films by direct laser writing.
abstract: In this study, we demonstrate that porous silicon films can be ablated by the pulsed nitrogen laser of a commercial MALDI mass spectrometer. The extent of laser-induced ablation was found to depend on the doping level and surface chemistry of the porous silicon film. Using direct laser writing with or without a mask, micropatterns were generated on the porous silicon surface. These micropatterns were subsequently used to guide the growth of mammalian cells including neuroblastoma. Excellent selectivity of cell growth toward the laser-ablated regions was established.
authors.affiliation: School of Chemistry, Physics and Earth Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001 Australia.
authors.forename: Yit-Lung
authors.initials: YL
authors.lastname: Khung
authors.forename: Sean D
authors.initials: SD
authors.lastname: Graney
authors.forename: Nicolas H
authors.initials: NH
authors.lastname: Voelcker
mesh_terms: D001709:Biotechnology / Q000379:methods*; D002448:Cell Adhesion; D018929:Cell Culture Techniques / Q000295:instrumentation* / Q000379:methods; D045744:Cell Line, Tumor; D002478:Cells, Cultured; D002616:Chemical Engineering; D006801:Humans; D007834:Lasers; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence; D049329:Nanostructures; D009584:Nitrogen / Q000737:chemistry*; D016062:Porosity; D012825:Silicon / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D009584:Nitrogen; D012825:Silicon