title: Water percolation governs polymorphic transitions and conductivity of DNA.
abstract: We report on the first computer simulation studies of the percolation transition of water at the surface of the DNA double helix. With increased hydration, the ensemble of small clusters merges into a spanning water network via a quasi-two-dimensional percolation transition. This transition occurs strikingly close to the hydration level where the B form of DNA becomes stable in experiment. Formation of spanning water networks results in sigmoidlike acceleration of long-range ion transport in good agreement with experiment.
authors.affiliation: Physical Chemistry, Dortmund University, Otto-Hahn-Strasse 6, Dortmund, D-44227, Germany. brov@heineken.chemie.uni-dortmund.de
authors.forename: Ivan
authors.initials: I
authors.lastname: Brovchenko
authors.forename: Aliaksei
authors.initials: A
authors.lastname: Krukau
authors.forename: Alla
authors.initials: A
authors.lastname: Oleinikova
authors.forename: Alexey K
authors.initials: AK
authors.lastname: Mazur
mesh_terms: D001703:Biophysics / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D017136:Ion Transport; D007477:Ions; D009690:Nucleic Acid Conformation; D011336:Probability; D012964:Sodium / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D007477:Ions; D014867:Water; D004247:DNA; D012964:Sodium