The role of peptide modules in protein evolution.
Protein evolution shows interesting strategies to be used in protein design. During evolution the creation of new proteins has been accomplished by combining different peptide modules, i.e. evolutionary successful stable folding units. Thereby, the evolution of proteins has been greatly enhanced. Today this mechanism of recombining optimized building blocks to design new proteins has been introduced into applied molecular evolution.
Fuchs
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Max-Planck-Institute for Biophysical Chemistry, D-37077 Göttingen, Germany.
Buta
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