[Alteration of active and passive Wistar rats adaptive behavior in water-immersion model of depression].
Animals with active and passive behavioral strategy were selected among male Wistar rats by testing them in the T-maze. Using the results of rats testing in T-maze index of behavioral activity and index of behavioral passivity were calculated. The development of post-stress psychopathology and ils correlation with initial behavioral strategy were studied under water-immersion stress conditions consiclering individual alteration of adaptive behavior. Two paradigms were used--one time trial (stress) and two times trial (stress-restress). It was found that active and passive rats being subjected to inescapable aversive exposure develop different types of post-stress depression and only passive animals show the signs of posttraumatic stress disorder.
Shaliapina
V G
VG
Vershinina
E A
EA
Rakitskaia
V V
VV
Ryzhova
L Iu
LIu
Semenova
M G
MG
SEmenova
O G
OG
D000223:Adaptation, Psychological; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D003863:Depression / Q000209:etiology* / Q000503:physiopathology*; D007101:Immersion; D008297:Male; D023421:Models, Animal; D051381:Rats; D017208:Rats, Wistar; D013315:Stress, Psychological / Q000150:complications*; D014867:Water
D014867:Water