Diagnosis of leprosy: serological aspects.
The most convenient way of diagnosing an infectious disease is by serological methods. To improve the quality of diagnosis in leprosy, simple tests in addition to diagnosis by clinical signs, are necessary. Here, PGL-I based methods for detection of multibacillary and paucibacillary leprosy, have been revisited and newer methods are discussed.
Maeda
Yumi
Y
Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan. yumi@nih.go.jp
D000942:Antigens, Bacterial / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006017:Glycolipids / Q000276:immunology; D006801:Humans; D007918:Leprosy / Q000175:diagnosis* / Q000382:microbiology; D008565:Membrane Proteins / Q000276:immunology; D009166:Mycobacterium leprae / Q000276:immunology; D012698:Serologic Tests / Q000379:methods*
D000942:Antigens, Bacterial; D006017:Glycolipids; D008565:Membrane Proteins; C500901:major membrane protein II, Mycobacterium leprae; C045169:phenolic glycolipid I, Mycobacterium leprae