Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.
An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of molecular iodine (10 mol %) under solvent-free conditions at ambient temperature is presented.
Varala
Ravi
R
Indian Institute of Chemical Technology, Hyderabad-500 007, India.
Nuvula
Sreelatha
S
Adapa
Srinivas R
SR