title: Proteolysis of SARS-associated coronavirus spike glycoprotein.
authors.affiliation: University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
authors.forename: Graham
authors.initials: G
authors.lastname: Simmons
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Rennekamp
authors.forename: Paul
authors.initials: P
authors.lastname: Bates
mesh_terms: D056668:Cathepsin L; D002403:Cathepsins / Q000494:pharmacology; D002460:Cell Line; D003546:Cysteine Endopeptidases / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D011992:Endosomes / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008562:Membrane Glycoproteins / Q000737:chemistry*; D011485:Protein Binding; D045473:Severe acute respiratory syndrome-related coronavirus / Q000737:chemistry / Q000378:metabolism*; D064370:Spike Glycoprotein, Coronavirus; D013696:Temperature; D014357:Trypsin / Q000494:pharmacology; D014759:Viral Envelope Proteins / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D008562:Membrane Glycoproteins; D064370:Spike Glycoprotein, Coronavirus; D014759:Viral Envelope Proteins; D002403:Cathepsins; D014357:Trypsin; D003546:Cysteine Endopeptidases; C534281:CTSL protein, human; D056668:Cathepsin L