title: Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis.
abstract: Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis (LPE) were investigated through a retrospective study. Using case records, 48 dogs diagnosed with LPE were classified as survivors (n = 32) or non-survivors (n = 16), and the clinical and clinicopathological parameters were reviewed between the 2 groups by using univariate and multivariate prognostic analysis. Compared to the hospital population, non-survivors had an overrepresentation of the Shiba breed. Results of univariate analysis indicated that anorexia, severe weight loss, packed cell volume, and total protein were significantly associated with survival for 6 months after diagnosis. In multivariate analysis, anorexia and hypoproteinemia were significantly associated with survival. Furthermore, initial response to treatment was strongly associated with poor prognosis. Based on these clinical and laboratory parameters such as anorexia, hypoproteinemia and initial response to treatment, it may be possible to predict poor prognosis in canine LPE.
authors.affiliation: Department of Veterinary Internal Medicine Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Ohno
authors.forename: Satoka
authors.initials: S
authors.lastname: Konishi
authors.forename: Saku
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Ko
authors.initials: K
authors.lastname: Nakashima
authors.forename: Asuka
authors.initials: A
authors.lastname: Setoguchi
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Fujino
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayama
authors.forename: Hajime
authors.initials: H
authors.lastname: Tsujimoto
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000401:mortality*; D004285:Dogs; D004751:Enteritis / Q000175:diagnosis / Q000401:mortality / Q000662:veterinary*; D008214:Lymphocytes / Q000473:pathology*; D015999:Multivariate Analysis; D011379:Prognosis; D016019:Survival Analysis