title: Radical trifluoromethylation of ketone silyl enol ethers by activation with dialkylzinc.
abstract: [reaction: see text] The radical trifluoromethylation of ketone silyl enol ethers gave alpha-CF(3) ketones in good yields with wide scope of the ketonic substrates including acyclic ketones and cyclopentanone. The use of dialkylzinc to activate the silyl enol ethers is the key to the efficient radical trifluoromethylation.
authors.affiliation: Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152-8552, Japan. kmikami@o.cc.titech.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Mikami
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tomita
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Amikura
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Itoh