title: A putative Ariadne-like ubiquitin ligase is required for Dictyostelium discoideum development.
abstract: The Dictyostelium rbrA gene encodes a putative Ariadne ubiquitin ligase. rbrA(-) cells form defective slugs that cannot phototax. Prestalk cell numbers are reduced in rbrA(-) slugs, and these prestalk cells do not localize to the tip of slugs. Chimeric slugs containing wild-type cells could phototax and form fruiting bodies.
authors.affiliation: Department of Biological Sciences, Walla Walla College, 204 S. College Ave., College Place, WA 99324, USA.
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Whitney
authors.forename: Lacey J
authors.initials: LJ
authors.lastname: Pearson
authors.forename: Ryan
authors.initials: R
authors.lastname: Lunsford
authors.forename: Lisa
authors.initials: L
authors.lastname: McGill
authors.forename: Richard H
authors.initials: RH
authors.lastname: Gomer
authors.forename: David F
authors.initials: DF
authors.lastname: Lindsey
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004023:Dictyostelium / Q000166:cytology / Q000201:enzymology* / Q000254:growth & development*; D015870:Gene Expression; D017125:Genes, Protozoan / Q000235:genetics; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D013170:Spores / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011993:Recombinant Fusion Proteins; D044767:Ubiquitin-Protein Ligases