Clinical features associated with impulse control disorders in Parkinson disease.
In patients with Parkinson disease (PD), impulse control disorders (ICDs) such as hypersexuality and pathologic gambling and shopping can be devastating complications of antiparkinsonian treatment. To improve their detection, we investigated clinical features associated with ICDs. Subjects were participants in a longitudinal study of PD. ICDs were associated with use of dopamine agonists and depressed mood, disinhibition, irritability, and appetite disturbance.
Pontone
Gregory
G
Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Williams
James R
JR
Bassett
Susan Spear
SS
Marsh
Laur
L
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002986:Clinical Trials as Topic; D015897:Comorbidity; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis* / Q000453:epidemiology*; D018491:Dopamine Agonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000453:epidemiology*; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology
D018491:Dopamine Agonists