title: [Bilateral serous detachment of the neurosensory retina and retinal pigment epithelium with rip of the peripheral pigment epithelium].
abstract: METHODS
  A 52-year-old patient with atypical plasmocytoma presented with a bilateral serous detachment of the retina as well as a huge detachment of the pigment epithelium (PE) in the periphery. Shortly thereafter the PE ruptured. In the left eye this led to substantial central macular fibrosis.
  
  
  METHODS
  The clinically healthy patient showed a nephrotic syndrome; neither typical monoclonality was detectable nor was erythropoiesis or myelopoiesis reduced.
  
  
  METHODS
  To avoid further reduction of VA pars plana vitrectomy (ppV) with silicone oil tamponade and laser coagulation was performed. Clinical findings were reduced significantly and VA was stabilized for 2.5 years.
  
  
  CONCLUSIONS
  PE detachments and serous retinal detachments in patients with nephrotic syndrome are only mentioned in a few cases. However, a peripheral rupture of the PE to this extent seems to be very rare. Early ppV with silicone oil and laser coagulation may prevent further macular fibrosis.
authors.affiliation: Augenabteilung, Asklepios Klinik Nord, Campus Heidberg, Tangstedter Landstrasse 400, 22417 Hamburg. anhager@gmx.de
authors.forename: A
authors.initials: A
authors.lastname: Hager
authors.forename: W
authors.initials: W
authors.lastname: Wiegand
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D020256:Choroidal Neovascularization / Q000209:etiology / Q000601:surgery; D015897:Comorbidity; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy; D017075:Laser Coagulation; D007910:Lenses, Intraocular; D008558:Melphalan / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy; D009887:Ophthalmoscopy; D010954:Plasmacytoma / Q000188:drug therapy; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects; D012008:Recurrence; D051437:Renal Insufficiency / Q000188:drug therapy; D012086:Reoperation; D012163:Retinal Detachment / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery*; D012167:Retinal Perforations / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery*; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils; D011239:Prednisolone; D008558:Melphalan