Anastrozole-induced hepatotoxicity.
We present a case of hepatotoxicity induced by an aromatase-inhibiting hormonal antineoplastic drug (anastrazol) in an elderly woman. This is the first reported case in the literature.
Zapata
Eva
E
Gastroenterology and Hepatology Units, Mendaro Hospital, Mendaro, Gipúzkoa, Spain. ezapata@hmen.oskidetza.net
Zubiaurre
Leire
L
Bujanda
Luis
L
Piérola
Alberto
A
D000369:Aged, 80 and over; D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects* / Q000627:therapeutic use; D047072:Aromatase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D018275:Carcinoma, Lobular / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000150:complications; D008111:Liver Function Tests; D009325:Nausea / Q000139:chemically induced / Q000209:etiology; D009570:Nitriles / Q000009:adverse effects* / Q000627:therapeutic use; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use
D018931:Antineoplastic Agents, Hormonal; D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole