title: [Modification of a catalase by glutaraldehyde].
abstract: Polycondensation of a catalase (EC 1.11.1.6) with glutaraldehyde in order to stabilize the quaternary structure of an enzyme, maintain its activity, and protect it from thermal denaturation was studied. Synthesis showed a superequivalent utilization of the aldehyde groups relative to the catalase amine groups, as a result of the formation of glutaraldehyde oligomers linked to the enzyme.
authors.forename: R N
authors.initials: RN
authors.lastname: Mishaeva
authors.forename: L R
authors.initials: LR
authors.lastname: Gudkin
authors.forename: N P
authors.initials: NP
authors.lastname: Kuznetsov
mesh_terms: D000818:Animals; D002374:Catalase / Q000737:chemistry*; D002417:Cattle; D003432:Cross-Linking Reagents / Q000737:chemistry*; D005976:Glutaral / Q000737:chemistry*; D011489:Protein Denaturation; D020836:Protein Structure, Quaternary
chemical_list: D003432:Cross-Linking Reagents; D002374:Catalase; D005976:Glutaral