title: Pulmonary benign metastasizing leiomyoma: a report of 2 cases with different outcomes.
abstract: BACKGROUND
  Benign metastasizing leiomyoma (BML) of the lung is a rare manifestation of metastasis from a uterine myoma, in which its benign characteristics are maintained. The majority of cases are asymptomatic.
  
  
  METHODS
  Case 1 responded to the classic treatment of oophorectomy, after which an improvement in symptoms was achieved. In case 2, however, symptoms appeared following oophorectomy and were treated with raloxifene.
  
  
  CONCLUSIONS
  These cases show the uncertainty that exists with respect to the evolution and treatment of symptomatic BML. Raloxifene is a therapeutic agent that has not been widely studied for this purpose but should be considered for inclusion in the arsenal of therapeutic options available.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas, Campinas, Brazil. crislag@sigmanet.com.br
authors.forename: Cristina Laguna
authors.initials: CL
authors.lastname: Benetti-Pinto
authors.forename: Patrícia Magda
authors.initials: PM
authors.lastname: Soares
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Petta
authors.forename: Liliana A L
authors.initials: LA
authors.lastname: De Angelo-Andrade
mesh_terms: D000328:Adult; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D018231:Leiomyomatosis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology*; D010052:Ovariectomy; D020849:Raloxifene Hydrochloride / Q000627:therapeutic use; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000473:pathology*
chemical_list: D004965:Estrogen Antagonists; D020849:Raloxifene Hydrochloride