title: A possible predisposition to dilated cardiomyopathy in Huntaway dogs.
abstract: OBJECTIVE
  To compare the prevalence of dilated cardiomyopathy (DCM) in New Zealand Huntaway dogs with the prevalence of DCM in other breeds of dog.
  
  
  METHODS
  The necropsy database at Massey University was used to identify cases of DCM diagnosed between January 1999 and March 2006. Dogs were considered to have DCM if echocardiographic, gross necropsy, or histological findings were consistent with this diagnosis. The prevalence in Huntaways was then compared with the prevalence observed in all breeds of dog, as well as the prevalence observed in large breeds of dog.
  
  
  RESULTS
  Twelve dogs were identified with DCM. One was diagnosed using echocardiography, while the other 11 were diagnosed by gross necropsy examination. The gross diagnosis of DCM was confirmed histologically in 6/11 dogs. The prevalence of DCM in Huntaways was significantly higher than the prevalence seen in all breeds of dog (p=0.008), and the prevalence in large breeds of dog (p=0.025). All four Huntaways diagnosed with DCM were male, and had an average age of 4 years. Three dogs presented with symptoms attributable to impaired heart function while one presented with symptoms of chronic renal failure. The duration of clinical symptoms prior to presentation ranged between 1 day and 3 weeks.
  
  
  CONCLUSIONS
  The results of this study suggest that Huntaways may be predisposed to the development of DCM. Although the increased prevalence in this breed was significant, only small numbers of affected Huntaways were identified, and additional cases are required to confirm these preliminary findings.
  
  
  CONCLUSIONS
  Huntaways are the most common working dog in New Zealand. The premature loss of a working dog is expected to have a significant economic impact on farmers. Further investigation of DCM in Huntaways may allow measures to reduce the prevalence in this breed.
authors.affiliation: Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand. J.Munday@massey.ac.nz
authors.forename: J S
authors.initials: JS
authors.lastname: Munday
authors.forename: C B
authors.initials: CB
authors.lastname: Dyer
authors.forename: A C
authors.initials: AC
authors.lastname: Hartman
authors.forename: G M B
authors.initials: GM
authors.lastname: Orbell
mesh_terms: D000818:Animals; D001947:Breeding; D002311:Cardiomyopathy, Dilated / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D004285:Dogs; D005260:Female; D020022:Genetic Predisposition to Disease; D008297:Male; D009520:New Zealand / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors