Enantioselective separation and determination of single nonylphenol isomers.
It has recently become clear that an isomer specific view of technical 4-nonylphenol (NP) is absolutely necessary for the evaluation of the biological behavior of NP, raising additional questions concerning enantiomer specific effects. For the first time, in this study enantioselective HPLC was applied to enantiomeric separation of chiral NP isomers. A semipreparative separation of two NP isomers could be achieved. A GC-MS method has been developed for the simultaneous detection of three chiral NP isomers in water samples. Investigation of influent and effluent samples from a wastewater treatment plant in Germany indicated that enantioselective degradation could occur in the environment. In one examined influent, an enantiomer ratio of 1.7 for two different isomers was determined.
Zhang
Haifeng
H
Institute of Environmental Research, University of Dortmund, Otto-Hahn-Str. 6, D-44227 Dortmund, Germany.
Zuehlke
Sebastian
S
Guenther
Klaus
K
Spiteller
Michael
M
D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D005858:Germany; D007536:Isomerism; D010636:Phenols / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D010636:Phenols; D014874:Water Pollutants, Chemical; C025256:nonylphenol