Human microsporidioses.
Recent developments in microsporidiosis research include the increased utilization of molecular techniques for the investigation of clinical specimens as well as for epidemiological and phylogenetic studies. Special attention is given to studies reporting severe disseminated microsporidioses involving most organs in AIDS patients, and the increased number of HIV-seronegative and immunocompetent individuals with microsporidiosis. The potential efficacy of fumagillin (Sanofi Recherche, Gentilly, France) in infections caused by Enterocytozoon bieneusi, and the remission of intestinal microsporidiosis in HIV infected patients with antiretroviral therapy are also highlighted.
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Unité INSERM 313, CHU Pitié-Salpêtrière, 91 boulevard de l'Hôpital, 75013, Paris, France.