title: Methylazacalix[4]pyridine: en route to Zn2+-specific fluoresence sensors.
abstract: [structure: see text] Owing to the electronic nature of the bridging nitrogen atoms which can adopt different hybridizations and form various conjugations with the adjacent pyridine(s), methylazacalix[4]pyridine underwent conformation and cavity preorganization to highly selectively bind the Zn(2+) ion. Rigidification and coplanarity of the macrocyclic ring led to a great enhancement of fluorescence of the intrinsic fluorescent host molecule.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Laboratory of Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.
authors.forename: Han-Yuan
authors.initials: HY
authors.lastname: Gong
authors.forename: Qi-Yu
authors.initials: QY
authors.lastname: Zheng
authors.forename: Xiao-Hang
authors.initials: XH
authors.lastname: Zhang
authors.forename: De-Xian
authors.initials: DX
authors.lastname: Wang
authors.forename: Mei-Xiang
authors.initials: MX
authors.lastname: Wang
mesh_terms: D005453:Fluorescence; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D011725:Pyridines; D015032:Zinc