Formation of peroxisomes: present and past.
Eukaryotic cells contain functionally distinct, membrane enclosed compartments called organelles. Here we like to address two questions concerning this architectural lay out. How did this membrane complexity arise during evolution and how is this collection of organelles maintained in multiplying cells to ensure that new cells retain a complete set of them. We will try to address these questions with peroxisomes as a focal point of interest.
Tabak
H F
HF
Department of Cellular Protein Chemistry, University of Utrecht, Padualaan 8, NL-3548 CH Utrecht, The Netherlands. h.tabak@chem.uu.nl
Hoepfner
D
D
Zand
A v d
Av
Geuze
H J
HJ
Braakman
I
I
Huynen
M A
MA
D000818:Animals; D005075:Biological Evolution; D004721:Endoplasmic Reticulum / Q000502:physiology; D006801:Humans; D020675:Peroxisomes / Q000502:physiology*; D010802:Phylogeny