title: [Depression and the risk of Alzheimer's disease].
abstract: A population based cohort study consisting of 3346 participants aged 65-84 years was examined at baseline (1992-94) and after two and five years. The purpose was to examine whether a history of depression increased the risk of Alzheimer's disease (AD). History of depression was based on self-report and AD was diagnosed according to NINCDS-ADRDA. Logistic regression was used to calculate the odds ratio (OR (95% confidence interval)). Subjects with a history of depression had an increased risk of AD: Baseline (OR = 1,7 (1,0-2,7)); after two years (1,9 (1,0-3,3)); after five years (1,6 (0,9-2,7)).
authors.affiliation: Odense Universitetshospital, Psykiatrisk Afdeling P, DemensKlinik OUH. kjeld.andersen@dadlnet.dk
authors.forename: Kjeld
authors.initials: K
authors.lastname: Andersen
authors.forename: Annette
authors.initials: A
authors.lastname: Lolk
authors.forename: Per
authors.initials: P
authors.lastname: Kragh-Sørensen
authors.forename: Niels Erik
authors.initials: NE
authors.lastname: Petersen
authors.forename: Anders
authors.initials: A
authors.lastname: Green