title: 3-Hydroxypyrrolidines from epoxysulfonamides and dimethylsulfoxonium methylide.
abstract: N-Tosyl-protected 3-hydroxypyrrolidines are prepared by reaction of dimethylsulfoxonium methylide with readily available epoxysulfonamides.
authors.affiliation: Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UK OX1 3TA. david.hodgson@chem.ox.ac.uk
authors.forename: David M
authors.initials: DM
authors.lastname: Hodgson
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Fleming
authors.forename: Zhaoqing
authors.initials: Z
authors.lastname: Xu
authors.forename: Changxue
authors.initials: C
authors.lastname: Lin
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Stanway
mesh_terms: D000577:Amides / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000737:chemistry*; D006900:Hydroxylation; D000432:Methanol / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000737:chemistry*; D013454:Sulfoxides / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
chemical_list: D000577:Amides; D001388:Aziridines; D004852:Epoxy Compounds; D011759:Pyrrolidines; D013454:Sulfoxides; D013455:Sulfur; D000432:Methanol