Pregnancy with uterine vascular malformations associated with hemorrhagic hereditary telangiectasia: a case report.
BACKGROUND
Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant condition. It is rarely seen in pregnancy and even more rarely has uterine manifestations.


METHODS
A 29-year-old primigravid woman with HHT was noted to have vascular manifestations of her disease in the lower uterus, distal rectum, pelvis, and bladder before pregnancy. Prior to delivery, a case conference was held, involving representatives of the departments of vascular surgery, hematology, radiology, anaesthesiology, maternal-fetal medicine, neonatology, and laboratory medicine, and other appropriate health professionals. A successful elective Caesarean section was performed at term, with a good outcome for both mother and child.


CONCLUSIONS
regnancies in women with HHT and associated uterine vascular manifestations have been rarely reported, and published information is minimal. We present a case of a successful operative delivery following careful multidisciplinary antepartum care.
Dahlgren
Leanne S
LS
Department of Obstetrics and Gynaecology, University of British Columbia, Children's and Women's Hospital of British Columbia, Vancouver BC.
Effer
Sidney B
SB
Department of Obstetrics and Gynaecology, University of British Columbia, Children's and Women's Hospital of British Columbia, Vancouver BC.
McGillivray
Barbara C
BC
Department of Medical Genetics, University of British Columbia, Children's and Women's Hospital of British Columbia, Vancouver BC.
Pugash
Denise J
DJ
Department of Radiology and Ultrasound, University of British Columbia, Children's and Women's Hospital of British Columbia, Vancouver BC.
D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000235:genetics*; D011256:Pregnancy Outcome; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*; D014599:Uterus / Q000098:blood supply*