Measurement of microbicide acceptability among U.S. adolescent girls.
OBJECTIVE
Topical microbicides will only be effective if they are acceptable to potential users. The purpose of this study is to develop a scale to evaluate characteristics and aspects of topical microbicides that are important to adolescent girls.


METHODS
Girls (n = 207) completed a questionnaire on perceptions of microbicide-like products.


RESULTS
A principal components factor analysis with a varimax rotation produced a 6-factor solution. The mean factor scores suggested that girls saw the products positively. Age was positively correlated with "comparison to condoms" and "comfort while using" factor scores and inversely correlated with "negative impact on interpersonal relationships" factor score. Sexually transmitted infection (STI) history was related to higher scores on the "health benefits" and "pleasure" factors. Age, race/ethnicity, and STI history were not related to the other factor scores.


CONCLUSIONS
The current scale shows promise in assessment of microbicide acceptability, and in general, girls expressed positive views about microbicides.
Short
Mary B
MB
University of Houston - Clear Lake, Houston, Texas, USA.
Perfect
Michelle M
MM
Auslander
Beth A
BA
Devellis
Robert F
RF
Rosenthal
Susan L
SL
D000282:Administration, Intravaginal; D000293:Adolescent; D016497:Adolescent Health Services; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005990:Glycerol / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008055:Lipids / Q000008:administration & dosage / Q000627:therapeutic use; D010342:Patient Acceptance of Health Care; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000627:therapeutic use; D012749:Sexually Transmitted Diseases / Q000517:prevention & control*; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage / Q000627:therapeutic use
D000890:Anti-Infective Agents; D004338:Drug Combinations; D008055:Lipids; C085472:Replens; D014622:Vaginal Creams, Foams, and Jellies; C052495:lubrin; D011092:Polyethylene Glycols; D005990:Glycerol