Inherited myopathy in a young Great Dane.
A 3-year-old, male Great Dane was evaluated for an 18-month history of progressive weakness. Histologic evaluation of muscle biopsies revealed distinct cytoarchitectural changes that were indistinguishable from the central "core-like" structures previously described as central core myopathy in this breed. Clinical features of this inherited myopathy are described.
McMillan
Chantal J
CJ
Small Animal Clinical Sciences, Western College of Veterinary Medicine, Saskatoon, Saskatchewan. mcmillan@usask.ca
Taylor
Susan M
SM
Shelton
G Diane
GD
D000818:Animals; D001706:Biopsy / Q000662:veterinary; D004283:Dog Diseases / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology; D004285:Dogs; D020022:Genetic Predisposition to Disease; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D020512:Myopathy, Central Core / Q000151:congenital / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*