title: Clinical evaluation of an ointment with 10% metronidazole and 2% lidocaine in the treatment of alveolitis.
abstract: OBJECTIVE
  In this study, the authors evaluate the use of a 10% metronidazole and 2% lidocaine ointment, using a lanolin base and mint as flavoring, to treat alveolitis in humans.
  
  
  METHODS
  Twenty-five patients, with a diagnosis of alveolitis, were treated in the following way: locoregional anesthesia; surgical cleaning of the socket with alveolar curettes; saline solution irrigation with a 20 ml disposable syringe; and complete filling of the socket with the ointment.
  
  
  RESULTS
  The analysis of the results showed that the painful symptoms were severe before and on the day of the treatment in 17 (68%) of the 25 patients treated. Post-treatment analysis presented 2 patients (18%) with severe painful symptoms after 24 h of the treatment and complete remission of painful symptoms after 48 h of the treatment with the ointment.
  
  
  CONCLUSIONS
  Based on the results, it is possible to conclude that the 10% metronidazole and 2% lidocaine ointment, with mint flavoring and lanolin as a base, can be used to treat alveolitis.
authors.affiliation: Dentistry Post-Graduate Course, Department of Surgery and Integrated Clinic Discipline, Faculty of Dentistry, UNESP, São Paulo State University Araçatuba, Brazil.
authors.forename: L J
authors.initials: LJ
authors.lastname: Silva
authors.forename: W R
authors.initials: WR
authors.lastname: Poi
authors.forename: S R
authors.initials: SR
authors.lastname: Panzarini
authors.forename: T S
authors.initials: TS
authors.lastname: Rodrigues
authors.forename: L E
authors.initials: LE
authors.lastname: Simonato
mesh_terms: D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D004338:Drug Combinations; D004368:Dry Socket / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage*; D008875:Middle Aged; D009824:Ointments
chemical_list: D000779:Anesthetics, Local; D000890:Anti-Infective Agents; D004338:Drug Combinations; D009824:Ointments; D008795:Metronidazole; D008012:Lidocaine