Effects of hypomagnetic field on noradrenergic activities in the brainstem of golden hamster.
Previous studies found that elimination of the geomagnetic field (GMF) interferes with the normal brain functions, but the underlying mechanism remains unknown. The present study examined the effects of long-term exposures to a near-zero magnetic environment on the noradrenergic activities in the brainstem of golden hamsters. Both the content of norepinephrine (NE) and the density of NE-immunopositive neurons in the tissue decreased significantly after the treatment, and the effects could be progressive with time. These variations may substantially contribute to behavioral and mood disorders reported in other studies when animals are shielded from the GMF.
Zhang
Xu
X
State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Li
Jun-Feng
JF
Wu
Qi-Jiu
QJ
Li
Bing
B
Jiang
Jin-Chang
JC
D000818:Animals; D001933:Brain Stem / Q000378:metabolism* / Q000528:radiation effects; D006224:Cricetinae; D055593:Geological Phenomena; D005844:Geology; D008280:Magnetics; D008647:Mesocricetus; D009638:Norepinephrine / Q000378:metabolism* / Q000528:radiation effects
D009638:Norepinephrine