title: Synthesis of the G-C DNA base hybrid with a functional tail.
abstract: Molecules which possess the hydrogen bonding codes of both guanine and cytosine ("G-C DNA base hybrids") are known to organize in a hexagonal array both in solution and the solid state. Including an easily derivatizable functional group in the molecule allows the co-organization of virtually any species in the hexagonal periphery. Simple 5- and 6-step procedures are described for the synthesis of DNA base hybrids with tail groups which are terminated by electrophilic (primary bromide) and nucleophilic (primary alcohol) functions, respectively.
authors.affiliation: Department of Chemistry, University of California Davis, Davis, California 95616, USA. mascal@chem.ucdavis.edu
authors.forename: Mark
authors.initials: M
authors.lastname: Mascal
authors.forename: Steven C
authors.initials: SC
authors.lastname: Farmer
authors.forename: James R
authors.initials: JR
authors.lastname: Arnall-Culliford
mesh_terms: D003596:Cytosine / Q000138:chemical synthesis*; D006147:Guanine
chemical_list: D006147:Guanine; D003596:Cytosine