title: [Case of toxic shock-like syndrome affecting the neck].
abstract: Toxic shock-like syndrome (TSLS) is a form of rapidly progressing septic shock that can lead to multiple organ failure and has a high mortality rate of 30%. We report a rare case of TSLS affecting the head and neck. A 40-year-old man complained of redness and swelling of the neck with vomiting and diarrhea. His blood pressure dropped, and multiple organ failure occurred. Streptcoccus pyogenes, Group A, was identified in a blood culture, and he was diagnosed as having TSLS. He was treated with high-dose carbapenem, clindamysin, and gamma globulin. Continuous hemodiafiltration (CHDF) and PMX-DHP was applied to prevent sepsis and multiple organ failure. Debridement of the neck was performed on day 16. He recovered gradually and was discharged from hospital on day 45. A total resection is required to treat TSLS, but such a procedure is difficult to perform in the head and neck region. Our case improved without resection but after debridement and general control. TSLS should be first treated by medication and then by surgery, consisting of either debridement or resection.
authors.affiliation: Department of Otolaryngology, Takarazuka Municipal Hospital, Hyogo.
authors.forename: Naoki
authors.initials: N
authors.lastname: Saka
authors.forename: Toru
authors.initials: T
authors.lastname: Seo
authors.forename: Keiko
authors.initials: K
authors.lastname: Kashiba
authors.forename: Takaya
authors.initials: T
authors.lastname: Nishida
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination; D005914:Globins / Q000008:administration & dosage; D017583:Hemodiafiltration; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology / Q000517:prevention & control; D009333:Neck; D012772:Shock, Septic / Q000150:complications / Q000628:therapy*; D013290:Streptococcal Infections; D013297:Streptococcus pyogenes
chemical_list: D000900:Anti-Bacterial Agents; D005914:Globins