[Studies on extraction process optimization of Panax notogingseng saponins].
OBJECTIVE
To optimize the conditions for the extraction of panax notogingseng saponins (PNS).


METHODS
After selected extraction solvent and suitable particle, we employed orthogonal experimental design to examine the conditions for the extraction by determination of PNS.


RESULTS
Significant effect was observed only in extraction times.


CONCLUSIONS
The optimum condition for extraction of PNS was to extract panax notogingseng (Burk.) F. H. Chen with 10 times 70% ethanol for 1.5 hours for 3 times.
Qu
Lin-hai
LH
Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
Zheng
Ming
M
Lou
Yi-jia
YJ
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000008:administration & dosage; D005894:Panax / Q000737:chemistry*; D010316:Particle Size; D010598:Pharmacognosy; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000032:analysis / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013995:Time
D004365:Drugs, Chinese Herbal; D012503:Saponins; D000431:Ethanol