title: [Clinical observation on therapeutic effect of electroacupuncture at Sanyinjiao (SP 6) on peri-menopausal syndrome].
abstract: OBJECTIVE
  To objectively evaluate the effectiveness and safety of electroacupuncture (EA) at Sanyinjiao (SP 6) for treatment of peri-menopausal syndrome.
  
  
  METHODS
  All the patients enrolled were randomly divided into a treatment group and a control group. The treatment group were treated with EA at Sanyinjiao (SP 6) for 3 therapeutic courses, thrice each week, 30 min each time, one month constituting one course. The control group were treated with oral administration of nylestriol for 3 months, 2 mg each time, twice each month. For the menopausal patient, medroxyprogesterone was added from the third month of the treatment for 7 days, 6 mg each day. Changes of vasomotorial symptoms, mental symptoms and scores of Kupperman indexes before and after treatment for 1 month, 2 months and 3 months were investigated.
  
  
  RESULTS
  EA could significantly decrease the score of Kupperman indexes, improve vasomotorial symptoms and mental symptoms in the patient of peri-menopausal syndrome with no severe adverse effects. The control group in the score of Kupperman indexes was slightly higher than the treatment group with no significant difference between the two groups, but the treatment group in improvement of the vasomotorial symptoms was better than the control group and in improvement of mental symptoms was not as good as the control group.
  
  
  CONCLUSIONS
  EA at Sanyinjiao (SP 6) is effective and safe for treatment of peri-menopausal syndrome.
authors.affiliation: The First Affiliated Hospital of Anhui College of TCM, Hefei 230031, China. zhoujuntcm@sohu.com
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: Zheng-yu
authors.initials: ZY
authors.lastname: Qin
authors.forename: Wei-li
authors.initials: WL
authors.lastname: Li
authors.forename: Cui-ping
authors.initials: CP
authors.lastname: Zhang
authors.forename: Li-ying
authors.initials: LY
authors.lastname: Tian
authors.forename: Yi-juan
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Ling
authors.initials: L
authors.lastname: Hu
mesh_terms: D015669:Acupuncture Points; D015671:Electroacupuncture; D005260:Female; D006801:Humans; D008516:Medicine, Chinese Traditional; D008593:Menopause; D008875:Middle Aged; D013577:Syndrome