title: Rhodium-catalysed addition of organotrialkoxysilanes to alpha-substituted acrylic esters.
abstract: The cationic rhodium complex [Rh(cod)2][BF4] effectively catalyses the 1,4-addition of organotrialkoxysilanes to alpha-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and alpha-amino acid derivatives.
authors.affiliation: Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Hargrave
authors.forename: Jennifer
authors.initials: J
authors.lastname: Herbert
authors.forename: Gerwyn
authors.initials: G
authors.lastname: Bish
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Frost
mesh_terms: D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008670:Metals; D008958:Models, Molecular; D008968:Molecular Conformation; D053644:Naphthalimides / Q000737:chemistry; D009930:Organic Chemicals / Q000138:chemical synthesis*; D012238:Rhodium; D012821:Silanes / Q000737:chemistry*
chemical_list: D004952:Esters; D008670:Metals; D053644:Naphthalimides; D009930:Organic Chemicals; D012821:Silanes; D012238:Rhodium