A ratiometric and non-enzymatic luminescence assay for uric acid: differential quenching of lanthanide excited states by anti-oxidants.
The excited states of Tb and Eu complexes of a common macrocyclic ligand are quenched preferentially by electron transfer from the urate anion, allowing the creation of a new assay to measure uric acid in biological fluids.
Poole
Robert A
RA
Department of Chemistry, Durham University, South Road, Durham, UK DH1 3LE.
Kielar
Filip
F
Richardson
Siobhan L
SL
Stenson
Philip A
PA
Parker
David
D