title: Primary malignant melanoma of the uterine cervix: case report and review of the literature.
abstract: BACKGROUND
  Malignant melanoma of the uterine cervix is a rare neoplasm with poor prognosis. Diagnosis is confirmed by immunohistochemical methods and by exclusion of other primary sites of melanoma.
  
  
  METHODS
  In this paper, we are reporting a case of a 38-year-old patient with a malignant melanoma of the uterine cervix. Diagnosis was made by histological and immunohistochemical method. The tumor was stage IB1 of the International Federation of Gynecology and Obstetrics classification. Chest x-ray and abdominopelvic computed tomography scanning were normal. A radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy was performed. After performing combined radical surgery and irradiation, complete remission of the tumor was achieved. The patient has been followed for 24 months. She is well without any symptoms or signs of recurrence.
  
  
  CONCLUSIONS
  Malignant melanoma is usually misdiagnosed specially in the chronic form. The immunohistochemical study is useful for definite diagnosis. Treatment is not well established, and the disease histogenesis has been controversial for a long time.
authors.affiliation: Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Azam S
authors.initials: AS
authors.lastname: Mousavi
authors.forename: Freshteh
authors.initials: F
authors.lastname: Fakor
authors.forename: Zeinab
authors.initials: Z
authors.lastname: Nazari
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Ghaemmaghami
authors.forename: Farnaz Amouzegar
authors.initials: FA
authors.lastname: Hashemi
authors.forename: Mansour
authors.initials: M
authors.lastname: Jamali
mesh_terms: D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008545:Melanoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery