[Small cell carcinoma of the prostate: a case report].
A 79-year-old man was admitted to our department with a chief complaint of urinary incontinence. The prostate was enlarged (145 cc), although the serum level of prostate specific antigen (PSA) was within the normal range (1.09 ng/ml). Digital rectal examination showed an enlarged, irregular prostate with stony hardness. We performed a prostate biopsy and histological examinations indicated poorly differentiated adenocarcinoma with a Gleason score of 5+5=10. A computed tomographic (CT) scan revealed a prostatic tumor invading the bladder, seminal vesicle and rectum. He was diagnosed with a stage T4N1M0 adenocarcinoma of the prostate. He was started-on hormonal therapy, but died one month from the start of treatment. Histological and immunohistological examinations were repeated; suggesting small cell neuroendocrine carcinoma of the prostate.
Sasaki
Mitsuharu
M
The Department of Urology, Yamagata Prefectural Central Hospital.
Kobayashi
Takashi
T
Ono
Kunio
K
Sugano
Osamu
O
Sasao
Syunichi
S
Hoshi
Senji
S
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D051517:Digital Rectal Examination; D006801:Humans; D008297:Male; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen