NIS/H2SO4-Silica: a mild and efficient reagent system for the hydrolysis of thioglycosides.
Chemoselective hydrolysis of a variety of thioglycosides in the presence of a wide range of protecting groups has been achieved by using N-iodosuccinimide and H(2)SO(4) immobilized on silica in good to excellent yields.
Dasgupta
Somnath
S
Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India.
Roy
Bimalendu
B
Mukhopadhyay
Balaram
B
D006868:Hydrolysis; D007202:Indicators and Reagents; D012822:Silicon Dioxide / Q000737:chemistry*; D013388:Succinimides / Q000737:chemistry*; D013464:Sulfuric Acids / Q000737:chemistry*; D013865:Thioglycosides / Q000737:chemistry*
D007202:Indicators and Reagents; D013388:Succinimides; D013464:Sulfuric Acids; D013865:Thioglycosides; C008155:N-iodosuccinimide; D012822:Silicon Dioxide; C033158:sulfuric acid