[The influence of stimulation dopaminergic D, i D2 receptors in lateral geniculate body on flash visual evoked potentials (FVEP) in rats].
OBJECTIVE
The topic of this paper is to define the influence of stimulation dopaminergic D1 i D2 receptors in lateral geniculate body by flash visual evoked potentials (FVEP).


METHODS
Wistar rats were examined. There were stereotaxically implanted with guide caniula into the lateral geniculate body to inject substances and with VEPs electrodes on the skull and on the surface of visual cortex. VEPs curve before and after injection into the lateral geniculate body: 0.9% NaCl, agonists of dopamine receptors D1 - SKF 38393, and D2 Quinpirole and also the same agonist after antagonists D1 - SCH 23390, i D2 Sulpiride were analyzed.


RESULTS
Stimulating receptors D1 in the lateral geniculate body cause amplitude increase and shortness of latency. Quinpirole, agonist of D2 receptor do not significant change FVEPs curve.


CONCLUSIONS
Stimulation of D1 receptors in the lateral geniculate body can improve visual transmission throught it and response in the occipital cortex.
Plech
Agata R
AR
Katedry i Oddziału Klinicznego Okulistyki w Bytomiu Slaskiej Akademii Medycznej w Katowicach.
Herba
Ewa
E
Pojda-Wilczek
Dorota
D
Makowiecka-Obidzińska
Katarzyna
K
Pojda
Stefan M
SM
Plech
Andrzej
A
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D018491:Dopamine Agonists / Q000494:pharmacology; D018492:Dopamine Antagonists / Q000494:pharmacology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005829:Geniculate Bodies / Q000502:physiology*; D008845:Microinjections; D009778:Occipital Lobe / Q000502:physiology; D010775:Photic Stimulation; D019257:Quinpirole / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D017447:Receptors, Dopamine D1 / Q000502:physiology*; D017448:Receptors, Dopamine D2 / Q000819:agonists / Q000502:physiology*; D013469:Sulpiride / Q000494:pharmacology
D018491:Dopamine Agonists; D018492:Dopamine Antagonists; D017447:Receptors, Dopamine D1; D017448:Receptors, Dopamine D2; D019257:Quinpirole; D013469:Sulpiride