title: Unusually high prevalence of nosocomial Panton-Valentine leukocidin-positive Staphylococcus aureus isolates in Cape Verde Islands.
abstract: Characterization of nosocomial methicillin-susceptible Staphylococcus aureus isolates from Cape Verde showed that (i) Panton-Valentine leukocidin genes were present in 35% of the isolates and (ii) half of the collection had the same genetic background as methicillin-resistant pandemic clones. Introduction of the staphylococcal chromosome cassette mec (SCCmec) into virulent and epidemic isolates could pose serious threats to public health.
authors.affiliation: The Rockefeller University, 1230 York Ave., New York, NY 10021, USA.
authors.forename: M
authors.initials: M
authors.lastname: Aires-de-Sousa
authors.forename: T
authors.initials: T
authors.lastname: Conceição
authors.forename: H
authors.initials: H
authors.lastname: de Lencastre
mesh_terms: D000354:Africa, Western / Q000453:epidemiology; D001427:Bacterial Toxins / Q000235:genetics*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D005098:Exotoxins / Q000235:genetics*; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D016106:Methicillin Resistance; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics*
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin