Infertility in a man with oligoasthenoteratozoospermia associated with nonrobertsonian translocation t(9;15)(p10;q10).
OBJECTIVE
To analyze an unusual nonrobertsonian translocation t(9;15)(p10;q10) found in an infertile man with oligoasthenoteratozoospermia who had a normal phenotype.


METHODS
Case report with a review of scientific literature.


METHODS
Academic research environment.


METHODS
Infertile man with oligoasthenoteratozoospermia but otherwise apparently healthy.


METHODS
Peripheral blood lymphocytes were obtained for karyotyping, and metaphases were studied by the GBG fluorescence in situ hybridization (FISH) procedure.


METHODS
Physical examination, semen analysis, GBG banding, and FISH procedure.


RESULTS
The semen analysis revealed oligoasthenoteratozoospermia. The lymphocytic karyotype detected a translocation t(9;15)(p10;q10), and FISH procedure showed that the derived chromosome had a chromosome 15 centromere.


CONCLUSIONS
The association of unusual translocation with male factor infertility was described. To our knowledge no such association has been described previously in men whose clinical manifestation is only infertility.
Aydos
Sena Erdoğan
SE
Medico-Social Center, Cebeci Hospital, Ankara University School of Medicine, Ankara, Turkey. saydos@gmail.com
Tükün
Ajlan
A
D000328:Adult; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics*; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics*; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007248:Infertility, Male / Q000235:genetics; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D013091:Spermatogenesis / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*