One-pot carbanionic synthesis of P1,P2-diglycosyl, P1,P1,P2-triglycosyl, and P1,P1,P2,P2-tetraribosyl methylenediphosphonates.
Novel lithiated carbanions derived from ethyl glycosyl- and diglycosyl methylphosphonates were used in a direct and convenient synthesis of P1,P2-diglycosyl, P1,P1,P2-triglycosyl, and P1,P1,P2,P2-tetraribosyl methylenediphosphonates involving a one-pot methylidenediphosphonylation of sugars.
Grison
Claude
C
UMR 5032 CNRS-Université de Montpellier II-ERT 5, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex 5, France. cgrison@univ-montp2.fr
Chibli
Hicham
H
Barthès
Nicolas
N
Coutrot
Philippe
P
D063065:Organophosphonates / Q000138:chemical synthesis*
D063065:Organophosphonates