Fat-soluble vitamin deficiency in pregnancy: a case report and review of abetalipoproteinemia.
BACKGROUND
Abetalipoproteinemia (ABL) is a metabolic disorder resulting in poor absorption of fat-soluble vitamins.


METHODS
Two pregnancies in a woman with ABL are reported, contrasting outcomes with subtherapeutic and normal vitamin levels.


CONCLUSIONS
Fat-soluble vitamin levels in pregnancy are critical for many aspects of fetal development. This report details a congenital ophthalmologic finding that may be associated with vitamin A deficiency.
Gaudet
Laura M
LM
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Kingston General Hospital, Queen's University, Kingston ON.
MacKenzie
Jennifer
J
Department of Medical Genetics, Kingston General Hospital, Queen's University, Kingston ON.
Smith
Graeme N
GN
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Kingston General Hospital, Queen's University, Kingston ON.
D000012:Abetalipoproteinemia / Q000150:complications*; D000328:Adult; D001361:Avitaminosis / Q000150:complications* / Q000209:etiology*; D003103:Coloboma / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D047109:Fetal Development / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009751:Nutritional Requirements; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011256:Pregnancy Outcome; D014802:Vitamin A Deficiency / Q000150:complications / Q000209:etiology; D014811:Vitamin E Deficiency / Q000150:complications / Q000209:etiology