title: Myocardial involvement in rocky mountain spotted fever: a case report and review.
abstract: Rocky Mountain Spotted Fever (RMSF), caused by Rickettia rickettsii, is a serious tickborne illness that is endemic in the southeastern United States. Although it is most commonly known as a cause of fever and rash, it can have systemic manifestations. The myocardium may rarely be involved, with symptoms that can mimic those of acute coronary syndromes. This report describes a case of serologically proven RMSF causing symptomatic myocarditis, manifested by chest pain, elevated cardiac enzyme levels, and decrease myocardial function. After treatment with antibiotics, the myocarditis resolved. Thus, although unusual, the clinician should be aware of myocardial disease in patients with appropriate exposure histories or other clinical signs of RMSF. Close monitoring and an aggressive approach are essential to reduce mortality rates.
authors.affiliation: Division of Infectious Diseases, Vanderbilt University Department of Medicine, Nashville, Tennessee, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Doyle
authors.forename: Karan S
authors.initials: KS
authors.lastname: Bhalla
authors.forename: James M
authors.initials: JM
authors.lastname: Jones
authors.forename: David M
authors.initials: DM
authors.lastname: Ennis
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009205:Myocarditis / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D012284:Rickettsia rickettsii; D012373:Rocky Mountain Spotted Fever / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents