title: Single-versus multidetector-row CT: comparison of sedation rates, conventional angiograms and motion artefacts in young children following liver transplantation.
abstract: OBJECTIVE
  The aim of this study was to determine whether the use of multidetector computed tomography (MDCT) is associated with decreased sedation, frequency of motion artefacts and conventional angiograms compared with single-detector CT (SDCT).
  
  
  METHODS
  CT examinations performed in young children between January 1993 and June 2005 were reviewed retrospectively. Prior to September 2000, SDCT was used; after that period, MDCT was used. The examinations obtained during these two periods were compared for the frequency of sedation, motion artefacts, and conventional angiograms. Statistical comparison between the two groups was determined by using the chi(2) test.
  
  
  RESULTS
  A total of 126 infants and children younger than 6 years of age underwent 134 CT examinations. Eighty-eight were obtained with a SDCT (65%) (group 1) and 46 with a MDCT (35%) (group 2). Sedation was required in 31/88 (35%) CT examinations in group 1 and in 6/46 (13%) in group 2. Conventional angiography was performed in 20/88 (22%) cases in group 1 and in 6/46 (13%) in group 2. Motion artefacts were present in 8/88 (9%) CT examinations in group 1 and in 4/46 (8%) in group 2. There was significant statistical difference with regard to sedation and angiography rates between the two groups (p<0.001) whereas there was no significant difference with regard to motion artefacts (p>1).
  
  
  CONCLUSIONS
  MDCT can reduce the need for sedation and conventional angiography in children after liver transplantation. There is no effect on patient motion artefacts.
authors.affiliation: Department of Radiology, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F. Sforza 35, I-2012 Milan, Italy. alemos@sirm.org
authors.forename: A A
authors.initials: AA
authors.lastname: Lemos
authors.forename: M J
authors.initials: MJ
authors.lastname: Siegel
authors.forename: G
authors.initials: G
authors.lastname: Rossi
authors.forename: F
authors.initials: F
authors.lastname: Somalvico
authors.forename: U
authors.initials: U
authors.lastname: Cioffi
authors.forename: P R
authors.initials: PR
authors.lastname: Biondetti
mesh_terms: D000284:Administration, Oral; D000792:Angiography / Q000706:statistics & numerical data; D016477:Artifacts; D002648:Child; D002675:Child, Preschool; D002697:Chloral Hydrate / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000627:therapeutic use*; D007091:Image Processing, Computer-Assisted; D007223:Infant; D007275:Injections, Intravenous; D016031:Liver Transplantation / Q000000981:diagnostic imaging*; D008297:Male; D009038:Motion; D010424:Pentobarbital / Q000008:administration & dosage / Q000627:therapeutic use; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D006993:Hypnotics and Sedatives; D002697:Chloral Hydrate; D010424:Pentobarbital