title: [Difficulties in differential diagnosis of Sjögren's syndrome and systemic lupus erythematosus].
abstract: Sjögren's Syndrome (SS) is the second most common autoimmune disorder after rheumatoid arthritis (RA). It can be found as a lone condition (primary Sjögren's Syndrome) or may accompany other autoimmune rheumatic diseases (secondary Sjögren's Syndrome). Despite such frequent occurrence, accurate diagnosis of Sjögren Syndrome is difficult. These difficulties result from highly variable symptoms of SS as well as from common presence of other autoimmune disorders. In the following article authors present current knowledge concerning clinical symptoms, diagnostic methods and latest clinical guidelines on the diagnosis of SS. Differential diagnosis of SS and systemic lupus erythematosus (SLE) is also discussed.
authors.affiliation: Małopolskie Centrum Reumatologii, Immunologii i Rehabilitacji Szpitala Specjalistycznego im. J. Dietla w Krakowie.
authors.forename: Piotr
authors.initials: P
authors.lastname: Krawiec
authors.forename: Bogdan
authors.initials: B
authors.lastname: Batko
authors.forename: Antoni
authors.initials: A
authors.lastname: Skura
authors.forename: Teresa
authors.initials: T
authors.lastname: Adamek-Guzik
authors.forename: Marta
authors.initials: M
authors.lastname: Cześnikiewicz-Guzik
authors.forename: Marcin
authors.initials: M
authors.lastname: Krzanowski
authors.forename: Iwona
authors.initials: I
authors.lastname: Rydz-Stryszowska
authors.forename: Natalia
authors.initials: N
authors.lastname: Ryszawa
authors.forename: Tomasz J
authors.initials: TJ
authors.lastname: Guzik
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D015415:Biomarkers; D003240:Connective Tissue Diseases / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D008947:Mixed Connective Tissue Disease / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; D015415:Biomarkers; D007070:Immunoglobulin A; D007074:Immunoglobulin G