title: Cerebrovascular disease.
abstract: OBJECTIVE
  Carotid endarterectomy remains the preferred surgical intervention for the prevention of stroke among patients with extracranial cerebrovascular disease. Subgroup analyses of the results of several multicentre trials have contributed substantially to our understanding of the appropriate selection of patients and the perioperative risk associated with this procedure.
  
  
  RESULTS
  This review describes recent advances in our understanding of the appropriate use of carotid endarterectomy, and outlines recent developments and strategies that are likely to influence the perioperative care of these patients.
  
  
  CONCLUSIONS
  As current clinical guidelines for the use of carotid endarterectomy unfold, anaesthesiologists can expect to care more frequently for older patients and those at increased risk of complications. The perioperative management of co-existing diseases, particularly the control of hypertension and the strategies aimed at reducing the risk of cardiac complications, will contribute substantially to reducing perioperative morbidity and mortality.
authors.affiliation: Department of Anesthesia and Perioperative Medicine, University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada. iherrick@uwo.ca
authors.forename: Ian A
authors.initials: IA
authors.lastname: Herrick