title: A case of candida albicans mediastinitis after heart transplantation successfully treated with caspofungin.
abstract: Reported here is a case of mediastinitis caused by candida albicans and Staphylococcus aureus following a heart transplantation that was successfully treated with caspofungin, antibiotics and mediastinal lavage. A review of the literature revealed that Candida albicans as a cause of mediastinitis has been rarely described. In the few existing reports, evolution was generally fatal, especially in immunocompromised patients, despite treatment with antifungal drugs and antibiotics.
authors.affiliation: Department of Cardiothoracic Surgery, CSK MSWiA, Poland. miroslaw.garlicki@cskmswia.pl
authors.forename: Mirosław
authors.initials: M
authors.lastname: Garlicki
authors.forename: Paweł
authors.initials: P
authors.lastname: Czub
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Filczak
authors.forename: Ryszard
authors.initials: R
authors.lastname: Wojdyga
authors.forename: Maciej
authors.initials: M
authors.lastname: Puchniewicz
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Labuś
authors.forename: Marek P
authors.initials: MP
authors.lastname: Ehrlich
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002176:Candida albicans; D002177:Candidiasis / Q000188:drug therapy*; D000077336:Caspofungin; D054714:Echinocandins; D016027:Heart Transplantation; D006801:Humans; D055666:Lipopeptides; D008297:Male; D008875:Middle Aged; D010456:Peptides, Cyclic / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D010456:Peptides, Cyclic; D000077336:Caspofungin