Coupling-isomerization-Claisen sequences - mechanistic dichotomies in hetero domino reactions.
A new coupling-isomerization-Claisen domino reaction starting from electron deficient halides and 1-(hetero)aryl propargyl trityl ethers dichotomizes in the concluding steps of the sequence and gives rise to the formation of tricyclo[3.2.1.0(2,7)]oct-3-enes, enones, 1H-isochromenes, or indans as a consequence of minute differences of substituent effects.
D'Souza
Daniel M
DM
Organisch-Chemisches Institut der Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, D-69120 Heidelberg, Germany.
Rominger
Frank
F
Müller
Thomas J J
TJ