title: Acquired C1 esterase inhibitor deficiency: An atypical first presentation intra-operatively.
abstract: We report a case of airway difficulties encountered as a result of blistering, oedema and bleeding from the oropharyngeal mucosa of an 85-year-old female undergoing an elective excision of a submandibular neck lump. This led to a delay in extubation by several hours. The patient was subsequently found to have an acquired form of C1 esterase inhibitor deficiency considered to be consequent of haematological malignancy.
authors.affiliation: Department of Anaesthesia, The Ulster Hospital, Belfast, UK. davidhendron@doctors.org.uk
authors.forename: D
authors.initials: D
authors.lastname: Hendron
authors.forename: M
authors.initials: M
authors.lastname: Reid
mesh_terms: D000369:Aged, 80 and over; D000768:Anesthesia, General / Q000379:methods*; D001768:Blister / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency*; D004487:Edema / Q000150:complications; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D009061:Mouth Mucosa / Q000473:pathology; D006472:Oral Hemorrhage / Q000150:complications; D009960:Oropharynx; D014059:Tongue / Q000473:pathology
chemical_list: D003174:Complement C1 Inactivator Proteins