title: Isolated hepatic involvement of cat scratch disease in immunocompetent adults: Enhanced magnetic resonance imaging, pathological findings, and molecular analysis--two cases.
abstract: Visceral involvement in absence of lymphadenopathy is a rare manifestation in cat scratch disease; hepatic granulomas are rare, representing 0.3% of systemic manifestations of cat scratch disease, and gallbladder extension is a singular case. The present article refers to 2 rare cases of visceral cat scratch disease in immunocompetent adults with hepatic granulomatous inflammation, caused by Bartonella henselae infection, with gallbladder involvement in 1 case and no lymphadenopathy. Histological features demonstrated the presence of inflammatory necrotizing granulomatous nonneoplastic process. Molecular studies (polymerase chain reaction) were performed to confirm the infectious etiology.
authors.affiliation: Department of Pathology, Cardarelli Hospital, Naples, Italy. gmarinomars@tiscali.it
authors.forename: Giuseppina Marino
authors.initials: GM
authors.lastname: Marsilia
authors.forename: Anna
authors.initials: A
authors.lastname: La Mura
authors.forename: Roberta
authors.initials: R
authors.lastname: Galdiero
authors.forename: Emilia
authors.initials: E
authors.lastname: Galdiero
authors.forename: Giovanni
authors.initials: G
authors.lastname: Aloj
authors.forename: Alfonso
authors.initials: A
authors.lastname: Ragozzino
mesh_terms: D015703:Antigens, CD / Q000235:genetics / Q000378:metabolism; D018952:Antigens, CD34 / Q000235:genetics / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000235:genetics / Q000378:metabolism; D018416:Bartonella henselae / Q000235:genetics / Q000472:pathogenicity*; D002372:Cat-Scratch Disease / Q000150:complications* / Q000276:immunology / Q000473:pathology*; D004269:DNA, Bacterial / Q000235:genetics; D005260:Female; D006099:Granuloma / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007121:Immunocompetence; D008099:Liver / Q000378:metabolism / Q000382:microbiology / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D018952:Antigens, CD34; D015214:Antigens, Differentiation, Myelomonocytic; D004269:DNA, Bacterial; C067980:CD68 antigen, human; D000097382:CD68 Molecule