Erythromycin alters the pharmacokinetics of bromocriptine by inhibition of organic anion transporting polypeptide C-mediated uptake.
Lu
Wen-Jen
WJ
Huang
Kelly
K
Lai
Ming-Liang
ML
Huang
Jin-Ding
JD
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000978:Antiparkinson Agents / Q000493:pharmacokinetics*; D001971:Bromocriptine / Q000493:pharmacokinetics*; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects / Q000378:metabolism; D018491:Dopamine Agonists / Q000493:pharmacokinetics; D004917:Erythromycin / Q000494:pharmacology*; D006801:Humans; D027381:Liver-Specific Organic Anion Transporter 1 / Q000187:drug effects* / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000978:Antiparkinson Agents; D018491:Dopamine Agonists; D027381:Liver-Specific Organic Anion Transporter 1; D001971:Bromocriptine; D004917:Erythromycin; D003577:Cytochrome P-450 Enzyme System; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human